BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv2070c
Length=244
Score E
Sequences producing significant alignments: (Bits) Value
gi|15609207|ref|NP_216586.1| cobalt-precorrin-6x reductase [Myco... 479 1e-133
gi|340627081|ref|YP_004745533.1| putative precorrin-6X reductase... 478 3e-133
gi|254232238|ref|ZP_04925565.1| precorrin-6x reductase cobK [Myc... 451 6e-125
gi|31793253|ref|NP_855746.1| cobalt-precorrin-6x reductase [Myco... 445 3e-123
gi|183983053|ref|YP_001851344.1| precorrin-6x reductase, CobK [M... 369 2e-100
gi|118617812|ref|YP_906144.1| cobalt-precorrin-6x reductase [Myc... 365 4e-99
gi|296165163|ref|ZP_06847711.1| precorrin-6x reductase [Mycobact... 357 9e-97
gi|240172459|ref|ZP_04751118.1| cobalt-precorrin-6x reductase [M... 347 1e-93
gi|118471787|ref|YP_888167.1| cobalt-precorrin-6x reductase [Myc... 335 3e-90
gi|118466900|ref|YP_881622.1| cobalt-precorrin-6x reductase [Myc... 335 3e-90
gi|254775090|ref|ZP_05216606.1| cobalt-precorrin-6x reductase [M... 335 3e-90
gi|41407913|ref|NP_960749.1| cobalt-precorrin-6x reductase [Myco... 333 9e-90
gi|254819627|ref|ZP_05224628.1| cobalt-precorrin-6x reductase [M... 332 4e-89
gi|342859786|ref|ZP_08716439.1| precorrin-4 C11-methyltransferas... 331 7e-89
gi|126435106|ref|YP_001070797.1| cobalt-precorrin-6x reductase [... 303 1e-80
gi|108799452|ref|YP_639649.1| cobalt-precorrin-6x reductase [Myc... 300 1e-79
gi|169629283|ref|YP_001702932.1| cobalt-precorrin-6x reductase [... 272 3e-71
gi|289443574|ref|ZP_06433318.1| precorrin-6x reductase CbiJ/CobK... 270 2e-70
gi|343927922|ref|ZP_08767388.1| precorrin-6X reductase [Gordonia... 236 2e-60
gi|289754180|ref|ZP_06513558.1| precorrin-6x reductase cobK [Myc... 233 2e-59
gi|326382297|ref|ZP_08203989.1| precorrin-6x reductase [Gordonia... 224 1e-56
gi|325676809|ref|ZP_08156482.1| precorrin-6x reductase [Rhodococ... 221 8e-56
gi|312139740|ref|YP_004007076.1| cobalt-precorrin-6a reductase c... 217 1e-54
gi|289570180|ref|ZP_06450407.1| precorrin-6x reductase cobK [Myc... 213 2e-53
gi|331696832|ref|YP_004333071.1| precorrin-6x reductase [Pseudon... 209 2e-52
gi|262202404|ref|YP_003273612.1| precorrin-6x reductase [Gordoni... 208 5e-52
gi|302529239|ref|ZP_07281581.1| precorrin-6x reductase CbiJ/CobK... 207 8e-52
gi|3287761|sp|Q53139.1|COBK_RHOER RecName: Full=Precorrin-6A red... 205 4e-51
gi|111017845|ref|YP_700817.1| precorrin-6A reductase [Rhodococcu... 205 4e-51
gi|134102397|ref|YP_001108058.1| precorrin-6A reductase [Sacchar... 204 1e-50
gi|322437631|ref|YP_004219721.1| precorrin-6x reductase [Acidoba... 203 2e-50
gi|291004218|ref|ZP_06562191.1| precorrin-6A reductase [Saccharo... 201 8e-50
gi|299138935|ref|ZP_07032112.1| precorrin-6x reductase [Acidobac... 201 1e-49
gi|284033032|ref|YP_003382963.1| precorrin-6x reductase [Kribbel... 198 6e-49
gi|345011367|ref|YP_004813721.1| precorrin-6x reductase [Strepto... 198 7e-49
gi|297194616|ref|ZP_06912014.1| cobalt-precorrin-6x reductase [S... 196 2e-48
gi|296139886|ref|YP_003647129.1| precorrin-6x reductase [Tsukamu... 195 6e-48
gi|333919696|ref|YP_004493277.1| Precorrin-6x reductase CbiJ/Cob... 195 6e-48
gi|294813431|ref|ZP_06772074.1| cobalt-precorrin-6x reductase [S... 192 3e-47
gi|323136566|ref|ZP_08071647.1| precorrin-6x reductase [Methyloc... 192 3e-47
gi|226306645|ref|YP_002766605.1| precorrin-6X reductase [Rhodoco... 191 7e-47
gi|305681128|ref|ZP_07403935.1| precorrin-6A reductase [Coryneba... 191 1e-46
gi|336177248|ref|YP_004582623.1| precorrin-6x reductase [Frankia... 189 3e-46
gi|38233822|ref|NP_939589.1| cobalt-precorrin-6x reductase [Cory... 189 3e-46
gi|337290706|ref|YP_004629727.1| Precorrin-6x reductase [Coryneb... 189 3e-46
gi|334696819|gb|AEG81616.1| Precorrin-6x reductase [Corynebacter... 189 4e-46
gi|300858444|ref|YP_003783427.1| precorrin-6x reductase [Coryneb... 188 7e-46
gi|226359978|ref|YP_002777756.1| precorrin-6X reductase [Rhodoco... 187 9e-46
gi|317123948|ref|YP_004098060.1| precorrin-6A reductase [Intrasp... 187 9e-46
gi|336115957|ref|YP_004570723.1| precorrin-6X reductase [Microlu... 185 4e-45
>gi|15609207|ref|NP_216586.1| cobalt-precorrin-6x reductase [Mycobacterium tuberculosis H37Rv]
gi|15841559|ref|NP_336596.1| cobalt-precorrin-6x reductase [Mycobacterium tuberculosis CDC1551]
gi|148661884|ref|YP_001283407.1| cobalt-precorrin-6x reductase [Mycobacterium tuberculosis H37Ra]
56 more sequence titles
Length=244
Score = 479 bits (1234), Expect = 1e-133, Method: Compositional matrix adjust.
Identities = 243/244 (99%), Positives = 244/244 (100%), Gaps = 0/244 (0%)
Query 1 VTRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
+TRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR
Sbjct 1 MTRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVA 120
EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVA
Sbjct 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVA 120
Query 121 EQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFAL 180
EQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFAL
Sbjct 121 EQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFAL 180
Query 181 LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAG 240
LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAG
Sbjct 181 LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAG 240
Query 241 LPSR 244
LPSR
Sbjct 241 LPSR 244
>gi|340627081|ref|YP_004745533.1| putative precorrin-6X reductase CobK [Mycobacterium canettii
CIPT 140010059]
gi|340005271|emb|CCC44425.1| putative precorrin-6X reductase CobK [Mycobacterium canettii
CIPT 140010059]
Length=244
Score = 478 bits (1230), Expect = 3e-133, Method: Compositional matrix adjust.
Identities = 242/244 (99%), Positives = 244/244 (100%), Gaps = 0/244 (0%)
Query 1 VTRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
+TRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR
Sbjct 1 MTRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVA 120
EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVA
Sbjct 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVA 120
Query 121 EQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFAL 180
EQGYSRVFLTTGRSGIAAFANSDAWFLIR+VTAPDGTALPRRHKLVLSRGPYGYHDEFAL
Sbjct 121 EQGYSRVFLTTGRSGIAAFANSDAWFLIRLVTAPDGTALPRRHKLVLSRGPYGYHDEFAL 180
Query 181 LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAG 240
LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAG
Sbjct 181 LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAG 240
Query 241 LPSR 244
LPSR
Sbjct 241 LPSR 244
>gi|254232238|ref|ZP_04925565.1| precorrin-6x reductase cobK [Mycobacterium tuberculosis C]
gi|124601297|gb|EAY60307.1| precorrin-6x reductase cobK [Mycobacterium tuberculosis C]
Length=247
Score = 451 bits (1159), Expect = 6e-125, Method: Compositional matrix adjust.
Identities = 228/228 (100%), Positives = 228/228 (100%), Gaps = 0/228 (0%)
Query 17 AKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHPFAV 76
AKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHPFAV
Sbjct 20 AKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHPFAV 79
Query 77 TITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGRSGI 136
TITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGRSGI
Sbjct 80 TITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGRSGI 139
Query 137 AAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRIDALVTKNSGG 196
AAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRIDALVTKNSGG
Sbjct 140 AAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRIDALVTKNSGG 199
Query 197 KMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR 244
KMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR
Sbjct 200 KMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR 247
>gi|31793253|ref|NP_855746.1| cobalt-precorrin-6x reductase [Mycobacterium bovis AF2122/97]
gi|121637955|ref|YP_978179.1| cobalt-precorrin-6x reductase [Mycobacterium bovis BCG str. Pasteur
1173P2]
gi|224990449|ref|YP_002645136.1| cobalt-precorrin-6x reductase [Mycobacterium bovis BCG str. Tokyo
172]
8 more sequence titles
Length=231
Score = 445 bits (1144), Expect = 3e-123, Method: Compositional matrix adjust.
Identities = 224/227 (99%), Positives = 225/227 (99%), Gaps = 0/227 (0%)
Query 18 KELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHPFAVT 77
K +PHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHPFAVT
Sbjct 5 KSCNPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERIDAVVDATHPFAVT 64
Query 78 ITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGRSGIA 137
ITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGRSGIA
Sbjct 65 ITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQGYSRVFLTTGRSGIA 124
Query 138 AFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRIDALVTKNSGGK 197
AFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRIDALVTKNSGGK
Sbjct 125 AFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRIDALVTKNSGGK 184
Query 198 MTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR 244
MTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR
Sbjct 185 MTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR 231
>gi|183983053|ref|YP_001851344.1| precorrin-6x reductase, CobK [Mycobacterium marinum M]
gi|183176379|gb|ACC41489.1| precorrin-6x reductase, CobK [Mycobacterium marinum M]
Length=242
Score = 369 bits (947), Expect = 2e-100, Method: Compositional matrix adjust.
Identities = 183/241 (76%), Positives = 209/241 (87%), Gaps = 0/241 (0%)
Query 1 VTRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
+TR+LLLGGT+EGRALA LHP V++VSSLAGRVP+PALP+GPVRIGGFGGV+GLR WL
Sbjct 1 MTRLLLLGGTSEGRALAARLHPQVDLVSSLAGRVPDPALPVGPVRIGGFGGVDGLRRWLV 60
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVA 120
+ERIDAVVDATHPFA T+TAHAAQVC EL LP++VLARPPWDPG A++ SDIEAA+ VA
Sbjct 61 DERIDAVVDATHPFAATMTAHAAQVCAELALPHIVLARPPWDPGAALVVRSDIEAAESVA 120
Query 121 EQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFAL 180
+Q +SR+FLTTGRSG AAF +SDAWFLIR VTAPDG +LPRRH+LVLSRGPY Y DE L
Sbjct 121 QQRFSRIFLTTGRSGTAAFIDSDAWFLIRAVTAPDGASLPRRHQLVLSRGPYHYDDEVRL 180
Query 181 LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAG 240
LRE RIDALVTKNSGG MTRAKLDAA AL + VVM+ARP LPAGV++V +V AA WVA
Sbjct 181 LREHRIDALVTKNSGGAMTRAKLDAAGALDVPVVMVARPRLPAGVSSVGTVEEAAAWVAL 240
Query 241 L 241
L
Sbjct 241 L 241
>gi|118617812|ref|YP_906144.1| cobalt-precorrin-6x reductase [Mycobacterium ulcerans Agy99]
gi|118569922|gb|ABL04673.1| precorrin-6x reductase, CobK [Mycobacterium ulcerans Agy99]
Length=242
Score = 365 bits (936), Expect = 4e-99, Method: Compositional matrix adjust.
Identities = 181/241 (76%), Positives = 207/241 (86%), Gaps = 0/241 (0%)
Query 1 VTRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
+TR+LLLGGT+EGRALA LHP V++VSSLAGRVP+PALP+GPVRIG FGGV+GLR WL
Sbjct 1 MTRLLLLGGTSEGRALAARLHPQVDLVSSLAGRVPDPALPVGPVRIGRFGGVDGLRRWLV 60
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVA 120
+ERIDAVVDATHPFA T+TAHAAQVC EL LP++VLARPPWDPG A++ SDIEA + VA
Sbjct 61 DERIDAVVDATHPFAATMTAHAAQVCAELALPHIVLARPPWDPGAALVVRSDIEAVESVA 120
Query 121 EQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFAL 180
+Q +SR+FLTTGRSG AAF +SDAWFLIR VTAPDG +LPRRH+LVLSRGPY Y DE L
Sbjct 121 QQRFSRIFLTTGRSGTAAFIDSDAWFLIRAVTAPDGASLPRRHQLVLSRGPYHYDDEVRL 180
Query 181 LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAG 240
LRE RIDALVTKNSGG MTRAKLDAA AL + VVM+ARP LPAGV++V +V AA WVA
Sbjct 181 LREHRIDALVTKNSGGAMTRAKLDAAGALDVPVVMVARPRLPAGVSSVGTVEEAAAWVAR 240
Query 241 L 241
L
Sbjct 241 L 241
>gi|296165163|ref|ZP_06847711.1| precorrin-6x reductase [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295899471|gb|EFG78929.1| precorrin-6x reductase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=242
Score = 357 bits (916), Expect = 9e-97, Method: Compositional matrix adjust.
Identities = 178/236 (76%), Positives = 203/236 (87%), Gaps = 0/236 (0%)
Query 3 RVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREE 62
RVLLLGGTAEGRALA+ LHP V+IVSSLAGRVP+PALP+GPVR+GGFGGV+GLR WL EE
Sbjct 2 RVLLLGGTAEGRALAQALHPRVDIVSSLAGRVPDPALPVGPVRVGGFGGVDGLRRWLLEE 61
Query 63 RIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQ 122
I AV+DATHPFA T+TAHAAQVCGELG+P+LVLARP WDPG+AI+ SD +AA++VAEQ
Sbjct 62 NIGAVIDATHPFAATMTAHAAQVCGELGIPHLVLARPAWDPGSAIVVESDSKAAEIVAEQ 121
Query 123 GYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLR 182
G+SRVFLTTGRSG AFA+SDAWFLIR VT PD ALPR H++VLSRGPY Y E ALLR
Sbjct 122 GFSRVFLTTGRSGTKAFADSDAWFLIRAVTRPDAAALPRHHRVVLSRGPYRYDGELALLR 181
Query 183 EQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWV 238
E RIDALVTKNSGG++TRAKLDAAAAL I V+M+ARP LPA V +V SV A W+
Sbjct 182 EHRIDALVTKNSGGELTRAKLDAAAALSIPVLMVARPPLPAAVTSVGSVDEAVEWL 237
>gi|240172459|ref|ZP_04751118.1| cobalt-precorrin-6x reductase [Mycobacterium kansasii ATCC 12478]
Length=242
Score = 347 bits (889), Expect = 1e-93, Method: Compositional matrix adjust.
Identities = 185/241 (77%), Positives = 202/241 (84%), Gaps = 0/241 (0%)
Query 1 VTRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
+TR+LLLGGTAEGRALA LHPHV+IVSSLAGRVP+PALP+GPVRIGGFGGV+GLR WL
Sbjct 1 MTRLLLLGGTAEGRALAARLHPHVDIVSSLAGRVPDPALPVGPVRIGGFGGVDGLRRWLV 60
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVA 120
+E IDAVVDATHPFA TITAHAAQVCGEL PYLVLARPPWDPG AI+ SD +AA+ V
Sbjct 61 DEHIDAVVDATHPFAATITAHAAQVCGELNKPYLVLARPPWDPGDAIVVASDTQAAEAVE 120
Query 121 EQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFAL 180
Q + R+FLTTGRSG+ AFA S AWFLIR VTAPD T LPRRH+LVLSRGPY Y DE L
Sbjct 121 HQHFRRIFLTTGRSGVKAFAGSAAWFLIRAVTAPDDTVLPRRHQLVLSRGPYRYDDELGL 180
Query 181 LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAG 240
LRE I ALVTKNSGG MTRAKLDAAAAL I VVM+ARP LPAG+A V +V AA WVAG
Sbjct 181 LREHDIGALVTKNSGGDMTRAKLDAAAALDIPVVMVARPPLPAGIATVGTVAEAAAWVAG 240
Query 241 L 241
L
Sbjct 241 L 241
>gi|118471787|ref|YP_888167.1| cobalt-precorrin-6x reductase [Mycobacterium smegmatis str. MC2
155]
gi|118173074|gb|ABK73970.1| precorrin-6x reductase [Mycobacterium smegmatis str. MC2 155]
Length=251
Score = 335 bits (860), Expect = 3e-90, Method: Compositional matrix adjust.
Identities = 169/242 (70%), Positives = 195/242 (81%), Gaps = 3/242 (1%)
Query 3 RVLLLGGTAEGRALAKELHP---HVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWL 59
RVLLLGGT E RALA LHP +E++SSLAGRVP+PALP+G VRIGGFGGVEG+R WL
Sbjct 8 RVLLLGGTGEARALAAALHPLQPEIEVISSLAGRVPDPALPVGQVRIGGFGGVEGMRRWL 67
Query 60 REERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVV 119
R+E IDAVVDATHPFA TIT HAAQVC ELGLP+LVLARP W PG AI+ SD EAA+VV
Sbjct 68 RDEGIDAVVDATHPFAETITTHAAQVCAELGLPHLVLARPAWSPGDAIVVASDTEAAEVV 127
Query 120 AEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFA 179
A++G+SRVFLTTGRSG +AF DAWFLIR VT PD LP RH+L+LSRGPY Y E A
Sbjct 128 AQRGFSRVFLTTGRSGTSAFRGVDAWFLIRAVTEPDAGTLPARHELLLSRGPYDYEGELA 187
Query 180 LLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVA 239
LLR+ RIDALVTKNSGG MT+ KLDAAA G++V+M+ RP LPAGV +V +V +A WV+
Sbjct 188 LLRDHRIDALVTKNSGGDMTQPKLDAAATAGVAVIMVDRPPLPAGVHSVTTVEQARDWVS 247
Query 240 GL 241
L
Sbjct 248 SL 249
>gi|118466900|ref|YP_881622.1| cobalt-precorrin-6x reductase [Mycobacterium avium 104]
gi|118168187|gb|ABK69084.1| precorrin-6x reductase [Mycobacterium avium 104]
Length=244
Score = 335 bits (860), Expect = 3e-90, Method: Compositional matrix adjust.
Identities = 175/228 (77%), Positives = 195/228 (86%), Gaps = 0/228 (0%)
Query 3 RVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREE 62
R+LLLGGT E RALAK LHP ++I+SSLAGRVP+PALP+GPVRIGGFGGV+GLR WLR+E
Sbjct 2 RLLLLGGTGEARALAKALHPRIDIISSLAGRVPDPALPVGPVRIGGFGGVDGLRRWLRDE 61
Query 63 RIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQ 122
IDAVVDATHPFA T+TAHAAQ C ELG+P+LVLARP WDPG A + SD AA+ VAEQ
Sbjct 62 HIDAVVDATHPFASTMTAHAAQACAELGVPHLVLARPAWDPGAATVVDSDTRAAETVAEQ 121
Query 123 GYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLR 182
GYSRVFLTTGRSG AF +SDAWFLIR VT PD T LPRRH++VLSRGPY Y DE A+L
Sbjct 122 GYSRVFLTTGRSGARAFKDSDAWFLIRAVTEPDATTLPRRHRVVLSRGPYRYDDELAMLG 181
Query 183 EQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDS 230
E RIDALVTKNSGG+MTRAKLDAAAAL I VVM+ARP LPAGV+AV S
Sbjct 182 EHRIDALVTKNSGGQMTRAKLDAAAALDIPVVMVARPALPAGVSAVGS 229
>gi|254775090|ref|ZP_05216606.1| cobalt-precorrin-6x reductase [Mycobacterium avium subsp. avium
ATCC 25291]
Length=244
Score = 335 bits (859), Expect = 3e-90, Method: Compositional matrix adjust.
Identities = 176/228 (78%), Positives = 194/228 (86%), Gaps = 0/228 (0%)
Query 3 RVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREE 62
R+LLLGGT E RALAK LHP ++I+SSLAGRVP+PALP+GPVRIGGFGGV+GLR WLR+E
Sbjct 2 RLLLLGGTGEARALAKALHPRIDIISSLAGRVPDPALPVGPVRIGGFGGVDGLRRWLRDE 61
Query 63 RIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQ 122
IDAVVDATHPFA T+TAHAAQ C ELGLP+LVLARP WDPG A + SD AA+ VAEQ
Sbjct 62 HIDAVVDATHPFASTMTAHAAQACAELGLPHLVLARPAWDPGAATVVDSDTRAAETVAEQ 121
Query 123 GYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLR 182
GYSRVFLTTGRSG AF +SDAWFLIR VT PD T LPRRH++VLSRGPY Y DE ALL
Sbjct 122 GYSRVFLTTGRSGARAFKDSDAWFLIRAVTEPDATTLPRRHRVVLSRGPYRYDDELALLG 181
Query 183 EQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDS 230
E RIDALVTKNSGG+MTRAKLDAAAAL I VVM+ARP LPA V+AV S
Sbjct 182 EHRIDALVTKNSGGQMTRAKLDAAAALDIPVVMVARPALPASVSAVGS 229
>gi|41407913|ref|NP_960749.1| cobalt-precorrin-6x reductase [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41396267|gb|AAS04132.1| CobK [Mycobacterium avium subsp. paratuberculosis K-10]
gi|336462052|gb|EGO40898.1| precorrin-6x reductase [Mycobacterium avium subsp. paratuberculosis
S397]
Length=244
Score = 333 bits (855), Expect = 9e-90, Method: Compositional matrix adjust.
Identities = 176/228 (78%), Positives = 194/228 (86%), Gaps = 0/228 (0%)
Query 3 RVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREE 62
R+LLLGGT E RALAK LHP ++I+SSLAGRVP+PALP+GPVRIGGFGGV+GLR WLR+E
Sbjct 2 RLLLLGGTGEARALAKALHPRIDIISSLAGRVPDPALPVGPVRIGGFGGVDGLRRWLRDE 61
Query 63 RIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQ 122
I AVVDATHPFA T+TAHAAQ C ELGLP+LVLARP WDPG A + SD AA+ VAEQ
Sbjct 62 HIGAVVDATHPFASTMTAHAAQACAELGLPHLVLARPAWDPGAATVVDSDTHAAEAVAEQ 121
Query 123 GYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLR 182
GYSRVFLTTGRSG AF +SDAWFLIR VT PD T LPRRH++VLSRGPY Y DE ALL
Sbjct 122 GYSRVFLTTGRSGARAFKDSDAWFLIRAVTEPDATTLPRRHRVVLSRGPYRYDDELALLG 181
Query 183 EQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDS 230
E RIDALVTKNSGG+MTRAKLDAAAAL I VVM+ARP LPAGV+AV S
Sbjct 182 EHRIDALVTKNSGGQMTRAKLDAAAALDIPVVMVARPALPAGVSAVGS 229
>gi|254819627|ref|ZP_05224628.1| cobalt-precorrin-6x reductase [Mycobacterium intracellulare ATCC
13950]
Length=242
Score = 332 bits (850), Expect = 4e-89, Method: Compositional matrix adjust.
Identities = 174/239 (73%), Positives = 197/239 (83%), Gaps = 0/239 (0%)
Query 3 RVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREE 62
RVLLLGGT E RALAK LHP V+++SSLAGRVP+PALP+GPVRIGGFGGV+GLR WLR+E
Sbjct 2 RVLLLGGTGEARALAKTLHPRVDVISSLAGRVPDPALPVGPVRIGGFGGVDGLRRWLRDE 61
Query 63 RIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQ 122
IDAVVDATHPFA T+TAHAA CG+L +P+L+LARP WDPG A++ SD AA VA Q
Sbjct 62 GIDAVVDATHPFAATMTAHAATACGQLRIPHLILARPAWDPGEALVVGSDRHAAQTVARQ 121
Query 123 GYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLR 182
GYSR+FLTTGRSG+ AFA SDAWFLIR VT PD +LPR H+LVLSRGPY Y +E ALLR
Sbjct 122 GYSRIFLTTGRSGVHAFAGSDAWFLIRAVTEPDSASLPRHHRLVLSRGPYRYDEEVALLR 181
Query 183 EQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGL 241
E RIDALVTKNSGG+MTRAKLDAAAAL + VVM+ARP LP GV V +V AA WV L
Sbjct 182 EHRIDALVTKNSGGQMTRAKLDAAAALEVPVVMVARPPLPEGVTTVGTVADAAEWVGAL 240
>gi|342859786|ref|ZP_08716439.1| precorrin-4 C11-methyltransferase [Mycobacterium colombiense
CECT 3035]
gi|342132918|gb|EGT86138.1| precorrin-4 C11-methyltransferase [Mycobacterium colombiense
CECT 3035]
Length=499
Score = 331 bits (848), Expect = 7e-89, Method: Compositional matrix adjust.
Identities = 179/241 (75%), Positives = 202/241 (84%), Gaps = 0/241 (0%)
Query 1 VTRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
+ RVLLLGGT E RALAK LHP V++VSSLAGRVP+PALP+GPVRIGGFGGV+GLR WL+
Sbjct 257 LMRVLLLGGTGEARALAKTLHPRVDVVSSLAGRVPDPALPVGPVRIGGFGGVDGLRRWLQ 316
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVA 120
+ERIDAVVDATHPFA T+TAHAA C E +P+L+LARP WDPG AI+ SD +AA+ VA
Sbjct 317 DERIDAVVDATHPFAATMTAHAAVACAESRIPHLILARPAWDPGGAIVVDSDADAAETVA 376
Query 121 EQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFAL 180
QGYSRVFLTTGRSG+ AFA SDAWFLIR VT PD +ALPR H+++LSRGPYGY DEFAL
Sbjct 377 RQGYSRVFLTTGRSGVRAFAGSDAWFLIRAVTDPDASALPRHHRVLLSRGPYGYDDEFAL 436
Query 181 LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAG 240
LRE RID LVTKNSGG MTRAKLDAAAAL ++VVM+ARP LPAGV V SV AA WV
Sbjct 437 LREHRIDVLVTKNSGGDMTRAKLDAAAALDVAVVMVARPPLPAGVLTVGSVAEAAEWVGA 496
Query 241 L 241
L
Sbjct 497 L 497
>gi|126435106|ref|YP_001070797.1| cobalt-precorrin-6x reductase [Mycobacterium sp. JLS]
gi|126234906|gb|ABN98306.1| precorrin-6A reductase [Mycobacterium sp. JLS]
Length=242
Score = 303 bits (777), Expect = 1e-80, Method: Compositional matrix adjust.
Identities = 161/239 (68%), Positives = 185/239 (78%), Gaps = 0/239 (0%)
Query 3 RVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREE 62
R+LLLGGT E RALA LHP VE++SSLAGRVP+PALP+G VRIGGFGGV+GLR WL +
Sbjct 2 RILLLGGTGEARALAAALHPDVEVISSLAGRVPDPALPVGQVRIGGFGGVDGLRRWLTDT 61
Query 63 RIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQ 122
+DAVVDATHPFA TITA AA VC +LGLP+L+LARP W G AI+ SD EAA VA +
Sbjct 62 PVDAVVDATHPFAATITATAAAVCADLGLPHLLLARPAWSAGDAILVSSDREAATTVAAK 121
Query 123 GYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLR 182
G+SR+FLTTGR+G+ AF +SDAWFLIR VT PD LPR H+L+LSRGPY Y DE A LR
Sbjct 122 GFSRIFLTTGRTGVDAFRDSDAWFLIRAVTPPDAEVLPRHHELLLSRGPYRYDDELAALR 181
Query 183 EQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGL 241
RI+ALVTKNSGG MTR KLDAAA LGI VVM+ RP +P GV V +V A WV L
Sbjct 182 THRIEALVTKNSGGDMTRPKLDAAATLGIPVVMVDRPPVPPGVRTVGTVPEAVAWVRSL 240
>gi|108799452|ref|YP_639649.1| cobalt-precorrin-6x reductase [Mycobacterium sp. MCS]
gi|119868565|ref|YP_938517.1| cobalt-precorrin-6x reductase [Mycobacterium sp. KMS]
gi|108769871|gb|ABG08593.1| precorrin-6A reductase [Mycobacterium sp. MCS]
gi|119694654|gb|ABL91727.1| precorrin-6A reductase [Mycobacterium sp. KMS]
Length=242
Score = 300 bits (767), Expect = 1e-79, Method: Compositional matrix adjust.
Identities = 161/239 (68%), Positives = 184/239 (77%), Gaps = 0/239 (0%)
Query 3 RVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREE 62
R+LLLGGT E RALA LHP VE++SSLAGRVP+PALP+G VRIGGFGGV+GLR WL E
Sbjct 2 RILLLGGTGEARALAAALHPDVEVISSLAGRVPDPALPVGQVRIGGFGGVDGLRRWLTET 61
Query 63 RIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQ 122
+ AVVDATHPFA TITA AA VC +LGLP+L+LARP W G AI+ SD EAA VA +
Sbjct 62 PVHAVVDATHPFAATITATAAAVCVDLGLPHLLLARPAWSAGDAILVSSDREAATTVAAK 121
Query 123 GYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLR 182
G+SR+FLTTGR+G+ AF +SDAWFLIR VT P LPR H+L+LSRGPY Y DE A+LR
Sbjct 122 GFSRIFLTTGRTGVDAFRDSDAWFLIRAVTPPGADVLPRHHELLLSRGPYRYDDELAVLR 181
Query 183 EQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGL 241
RIDALVTKNSGG MTR KLDAAA LGI VVM+ RP +P GV V +V A WV L
Sbjct 182 THRIDALVTKNSGGDMTRPKLDAAATLGIPVVMVDRPPVPPGVRTVGTVPEAVAWVRSL 240
>gi|169629283|ref|YP_001702932.1| cobalt-precorrin-6x reductase [Mycobacterium abscessus ATCC 19977]
gi|169241250|emb|CAM62278.1| Probable precorrin-6X reductase CobK [Mycobacterium abscessus]
Length=242
Score = 272 bits (696), Expect = 3e-71, Method: Compositional matrix adjust.
Identities = 138/234 (59%), Positives = 165/234 (71%), Gaps = 0/234 (0%)
Query 5 LLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREERI 64
++LGG+AE R LA+ L P ++ +SLAGRV NPA+P G +RIGGFGG GLR WL + I
Sbjct 1 MILGGSAEARELAERLAPRFDVTTSLAGRVNNPAVPAGALRIGGFGGEVGLRKWLLDNAI 60
Query 65 DAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADVVAEQGY 124
DAVVDATHPFA TIT +AA C LG+P+L++ RPPW G A + S EA D V QG+
Sbjct 61 DAVVDATHPFAATITENAAAACARLGIPHLIVRRPPWPAGDATVVSSAAEAKDAVVAQGF 120
Query 125 SRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQ 184
SRVFLT+GRS + AF SDAWFLIRVV LP RH L+LSRGPY +E L+R+
Sbjct 121 SRVFLTSGRSSVGAFLFSDAWFLIRVVEPMSADELPERHHLLLSRGPYTVAEETELMRQY 180
Query 185 RIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWV 238
I+ LVTKNSGG MT AKL+AAAALGI VVMI RP LP V+ V +V A WV
Sbjct 181 EIEVLVTKNSGGTMTSAKLEAAAALGIPVVMIDRPALPENVSTVSTVDAAQQWV 234
>gi|289443574|ref|ZP_06433318.1| precorrin-6x reductase CbiJ/CobK [Mycobacterium tuberculosis
T46]
gi|289416493|gb|EFD13733.1| precorrin-6x reductase CbiJ/CobK [Mycobacterium tuberculosis
T46]
Length=143
Score = 270 bits (689), Expect = 2e-70, Method: Compositional matrix adjust.
Identities = 136/137 (99%), Positives = 137/137 (100%), Gaps = 0/137 (0%)
Query 108 IAVSDIEAADVVAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVL 167
+AVSDIEAADVVAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVL
Sbjct 7 LAVSDIEAADVVAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVL 66
Query 168 SRGPYGYHDEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAA 227
SRGPYGYHDEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAA
Sbjct 67 SRGPYGYHDEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAA 126
Query 228 VDSVHRAAMWVAGLPSR 244
VDSVHRAAMWVAGLPSR
Sbjct 127 VDSVHRAAMWVAGLPSR 143
>gi|343927922|ref|ZP_08767388.1| precorrin-6X reductase [Gordonia alkanivorans NBRC 16433]
gi|343762145|dbj|GAA14314.1| precorrin-6X reductase [Gordonia alkanivorans NBRC 16433]
Length=247
Score = 236 bits (602), Expect = 2e-60, Method: Compositional matrix adjust.
Identities = 138/244 (57%), Positives = 163/244 (67%), Gaps = 8/244 (3%)
Query 3 RVLLLGGTAEGRALAKEL-HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
++L+LGGT E RALA L ++SSLAGRV NP LP+GPVRIGGFGGV+GLR WL
Sbjct 5 QILILGGTGEARALAASLTETGRSVISSLAGRVDNPRLPVGPVRIGGFGGVDGLREWLLS 64
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTA--IIAVSDI-EAADV 118
RI AV+DATHPFA TIT +AAQ E G+P L L R PW P A I V D+ AAD
Sbjct 65 NRIQAVIDATHPFAATITRNAAQAASEAGVPLLRLRREPWVPSDADRWIRVPDLATAADE 124
Query 119 VAEQGYSRVFLTTGRSGIAAFAN-SDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDE 177
V +G +RV LTTGR + FA D WFLIRVV P LP H+++ SRGPY Y E
Sbjct 125 VRHRG-NRVLLTTGRQDVGEFAGIDDVWFLIRVVDPPTAE-LPAHHEILRSRGPYDYDSE 182
Query 178 FALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMW 237
ALLRE RID LVTKNSGG +T+AKLDAAA +GI V+++ RP+ P V AV V A W
Sbjct 183 LALLRENRIDLLVTKNSGGSLTKAKLDAAATMGIDVIVVDRPIEP-DVPAVSEVAAAQAW 241
Query 238 VAGL 241
+ L
Sbjct 242 LERL 245
>gi|289754180|ref|ZP_06513558.1| precorrin-6x reductase cobK [Mycobacterium tuberculosis EAS054]
gi|289694767|gb|EFD62196.1| precorrin-6x reductase cobK [Mycobacterium tuberculosis EAS054]
Length=118
Score = 233 bits (595), Expect = 2e-59, Method: Compositional matrix adjust.
Identities = 117/118 (99%), Positives = 118/118 (100%), Gaps = 0/118 (0%)
Query 127 VFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRI 186
+FLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRI
Sbjct 1 MFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFALLREQRI 60
Query 187 DALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR 244
DALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR
Sbjct 61 DALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWVAGLPSR 118
>gi|326382297|ref|ZP_08203989.1| precorrin-6x reductase [Gordonia neofelifaecis NRRL B-59395]
gi|326199027|gb|EGD56209.1| precorrin-6x reductase [Gordonia neofelifaecis NRRL B-59395]
Length=255
Score = 224 bits (571), Expect = 1e-56, Method: Compositional matrix adjust.
Identities = 133/228 (59%), Positives = 157/228 (69%), Gaps = 7/228 (3%)
Query 3 RVLLLGGTAEGRALAKELHPH-VEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
RVL+LGGT E RA+A+ L V+ V+SLAGRV NP LP+G VR+GGFGGV+GL W+
Sbjct 9 RVLILGGTGEARAVARLLDDAGVDFVTSLAGRVANPRLPVGEVRVGGFGGVDGLADWIAA 68
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAI--IAVSDIEAA-DV 118
I V+DATHPFA IT +A G+ YL LARPPW P A VSDI AA
Sbjct 69 NGITTVLDATHPFATRITPNAVAAATRAGVRYLRLARPPWTPAAADRWAVVSDIRAAAGA 128
Query 119 VAEQGYSRVFLTTGRSGIAAFAN-SDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDE 177
VA++G R+FLTTGR +AAFA+ SDAWFLIRVV PDG LP R +++ SRGPY E
Sbjct 129 VADRG-GRIFLTTGRQDVAAFADVSDAWFLIRVVDEPDGP-LPPRSRVLRSRGPYDIAGE 186
Query 178 FALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGV 225
ALLRE ID LVTKNSGG+MT AKL AAA LGI VV++ RP P G+
Sbjct 187 RALLREHAIDVLVTKNSGGEMTSAKLRAAAELGIEVVVVERPAEPEGI 234
>gi|325676809|ref|ZP_08156482.1| precorrin-6x reductase [Rhodococcus equi ATCC 33707]
gi|325552357|gb|EGD22046.1| precorrin-6x reductase [Rhodococcus equi ATCC 33707]
Length=250
Score = 221 bits (562), Expect = 8e-56, Method: Compositional matrix adjust.
Identities = 133/242 (55%), Positives = 165/242 (69%), Gaps = 7/242 (2%)
Query 3 RVLLLGGTAEGRALAKELH--PHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
RVL+LGGT E R LA L P VE++SSLAGRV P LP+G VR+GGFGGV+GL WLR
Sbjct 3 RVLVLGGTGEARMLAARLADAPSVEVISSLAGRVREPVLPVGQVRVGGFGGVDGLTHWLR 62
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAII--AVSDIEA-AD 117
+ IDAVVDATHPFA ITA+AA +G+P LVL R W PG V D+ A A+
Sbjct 63 DNEIDAVVDATHPFAAQITANAAAATARVGVPLLVLRRREWAPGPGDDWHVVRDLAAGAE 122
Query 118 VVAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDE 177
VA G RVFLT GR G+ AFA+ D WFLIR + P+ LP + +L+L+RGP+ DE
Sbjct 123 AVAGLG-ERVFLTIGRQGVDAFADGDGWFLIRAIDPPE-VRLPEKSELLLARGPFTVGDE 180
Query 178 FALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMW 237
ALLRE+RID +VTKNSGG +T AKL+AA +G+ VVM+AR +P G+A+ + AA W
Sbjct 181 VALLRERRIDVVVTKNSGGALTSAKLEAARKVGVPVVMVARTPIPEGIASTSDLDVAAAW 240
Query 238 VA 239
A
Sbjct 241 AA 242
>gi|312139740|ref|YP_004007076.1| cobalt-precorrin-6a reductase cobk [Rhodococcus equi 103S]
gi|311889079|emb|CBH48392.1| cobalt-precorrin-6A reductase CobK [Rhodococcus equi 103S]
Length=250
Score = 217 bits (553), Expect = 1e-54, Method: Compositional matrix adjust.
Identities = 128/241 (54%), Positives = 159/241 (66%), Gaps = 5/241 (2%)
Query 3 RVLLLGGTAEGRALAKELH--PHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
RVL+LGGT E R LA L P VE++SSLAGRV P LP+G VR+GGFGGV+GL WLR
Sbjct 3 RVLVLGGTGEARMLAARLADAPSVEVISSLAGRVREPVLPVGQVRVGGFGGVDGLTHWLR 62
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAII--AVSDIEAADV 118
+ IDAVVDATHPFA ITA+A +G+P LVL R W PG V D+ A
Sbjct 63 DNEIDAVVDATHPFAAQITANATAATARVGVPLLVLRRREWAPGPGDDWHVVRDVAAGAE 122
Query 119 VAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
RVFLT GR G+ AFA+ D WFLIR + P+ LP + +L+L+RGP+ DE
Sbjct 123 AVAGLGERVFLTIGRQGVDAFADGDGWFLIRAIDPPE-VRLPEKAELLLARGPFTVGDEV 181
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWV 238
ALLRE+RID +VTKNSGG +T AKL+AA +G+ VVM+AR +P G+A+ + AA W
Sbjct 182 ALLRERRIDVVVTKNSGGALTSAKLEAARKVGVPVVMVARTPIPEGIASTSDLDVAAAWA 241
Query 239 A 239
A
Sbjct 242 A 242
>gi|289570180|ref|ZP_06450407.1| precorrin-6x reductase cobK [Mycobacterium tuberculosis T17]
gi|289750664|ref|ZP_06510042.1| precorrin-6x reductase cobK [Mycobacterium tuberculosis T92]
gi|289754181|ref|ZP_06513559.1| precorrin-6x reductase cobK [Mycobacterium tuberculosis EAS054]
gi|289543934|gb|EFD47582.1| precorrin-6x reductase cobK [Mycobacterium tuberculosis T17]
gi|289691251|gb|EFD58680.1| precorrin-6x reductase cobK [Mycobacterium tuberculosis T92]
gi|289694768|gb|EFD62197.1| precorrin-6x reductase cobK [Mycobacterium tuberculosis EAS054]
Length=127
Score = 213 bits (542), Expect = 2e-53, Method: Compositional matrix adjust.
Identities = 105/106 (99%), Positives = 106/106 (100%), Gaps = 0/106 (0%)
Query 1 VTRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
+TRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR
Sbjct 1 MTRVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTA 106
EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTA
Sbjct 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTA 106
>gi|331696832|ref|YP_004333071.1| precorrin-6x reductase [Pseudonocardia dioxanivorans CB1190]
gi|326951521|gb|AEA25218.1| precorrin-6x reductase [Pseudonocardia dioxanivorans CB1190]
Length=256
Score = 209 bits (533), Expect = 2e-52, Method: Compositional matrix adjust.
Identities = 127/247 (52%), Positives = 154/247 (63%), Gaps = 7/247 (2%)
Query 1 VTRVLLLGGTAEGRALAKEL--HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGW 58
++ VLLLGGT E R LA L P + +VSSLAGRV P+LP G VRIGGFGG GL W
Sbjct 8 LSTVLLLGGTGEARRLAGALAGTPGLRVVSSLAGRVKAPSLPAGEVRIGGFGGTTGLVQW 67
Query 59 LREERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWD--PGTAIIAVSDIEAA 116
LR+ R+DAVVDATHPFA ITAHA + C G P LVL+RP W PG V ++AA
Sbjct 68 LRDNRVDAVVDATHPFAARITAHAVRACAATGTPLLVLSRPGWTAGPGDRWHWVPSLDAA 127
Query 117 DVVAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHD 176
+ + RVFLTTGR +A FA+ D WFL+R V P+ +PR +++L+RGP+
Sbjct 128 ARLLPELGGRVFLTTGRQDLAVFADLDLWFLVRTVDPPE-PPVPRHAEVLLARGPFTVDG 186
Query 177 EFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPA--GVAAVDSVHRA 234
E LL RID +VTK+SGG MT AKL AA GI VV+ RP LP GV +SV A
Sbjct 187 ERDLLERHRIDVVVTKDSGGIMTAAKLIAARDAGIPVVVQRRPPLPTGPGVERAESVEDA 246
Query 235 AMWVAGL 241
W L
Sbjct 247 VTWTQNL 253
>gi|262202404|ref|YP_003273612.1| precorrin-6x reductase [Gordonia bronchialis DSM 43247]
gi|262085751|gb|ACY21719.1| precorrin-6x reductase [Gordonia bronchialis DSM 43247]
Length=244
Score = 208 bits (530), Expect = 5e-52, Method: Compositional matrix adjust.
Identities = 123/240 (52%), Positives = 153/240 (64%), Gaps = 5/240 (2%)
Query 3 RVLLLGGTAEGRALAKELHPH-VEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
RVL+LGGT E R LA ++++SSLAGRV +P LP+G VRIGGFGGV+GLR W+ +
Sbjct 4 RVLILGGTGEARDLAARAQAAGMDVISSLAGRVRDPRLPVGEVRIGGFGGVDGLRTWIGD 63
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPW--DPGTAIIAVSDIEAADVV 119
I AVVDATHPFA IT +A +P+L L RPPW DP V DI AA
Sbjct 64 NMIHAVVDATHPFATRITGNAVAATSATDVPFLRLRRPPWTPDPADDWSCVPDIAAAADE 123
Query 120 AEQGYSRVFLTTGRSGIAAFANSD-AWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
+RV LTTGR + AFA D AWFLIRVV P+ + LP H+++ SRGPY DE
Sbjct 124 IAGRRARVLLTTGRQDVGAFAGIDSAWFLIRVVDPPEAS-LPPHHQILRSRGPYHLDDER 182
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWV 238
LLR+ RID LVTKNSGG +T +KL AA LG+ V+M+ RP P G+ V + +A W+
Sbjct 183 NLLRDNRIDVLVTKNSGGGLTHSKLVAARELGVEVIMVERPPEPPGIRVVSNAAQAMSWL 242
>gi|302529239|ref|ZP_07281581.1| precorrin-6x reductase CbiJ/CobK [Streptomyces sp. AA4]
gi|302438134|gb|EFL09950.1| precorrin-6x reductase CbiJ/CobK [Streptomyces sp. AA4]
Length=242
Score = 207 bits (528), Expect = 8e-52, Method: Compositional matrix adjust.
Identities = 129/239 (54%), Positives = 151/239 (64%), Gaps = 6/239 (2%)
Query 4 VLLLGGTAEGRALAKELHPH-VEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREE 62
VL+LGGTAE R LA +LH V +VSSLAGRV P LP+G VRIGGFGGVEGL WLRE
Sbjct 3 VLILGGTAEARDLAAQLHERAVPVVSSLAGRVTRPRLPVGEVRIGGFGGVEGLTAWLREN 62
Query 63 RIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTA--IIAVSDIEAADVVA 120
+ AVVDATHPFA I A+A G+P L LARP W P D+E A +
Sbjct 63 GVRAVVDATHPFAERIGANAFHATQAAGIPLLRLARPGWQPSADDRWHWADDLEEAAALL 122
Query 121 EQGYSRVFLTTGRSGIAAFANSDA-WFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFA 179
+RVFLT+GR G+AAFA+ D WFLIR V P G LPR H++VL RGP+ E A
Sbjct 123 PGLGTRVFLTSGRQGLAAFADLDPLWFLIRCVDPP-GQPLPRAHEVVLDRGPHRVDGERA 181
Query 180 LLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWV 238
L+ E ID LVTK+SGG MT AKL AA LG+ VV++ RP P+ D V A WV
Sbjct 182 LMTEHDIDVLVTKDSGGAMTAAKLTAARELGLPVVIVRRPPRPSTTETAD-VAAAVEWV 239
>gi|3287761|sp|Q53139.1|COBK_RHOER RecName: Full=Precorrin-6A reductase; AltName: Full=Precorrin-6X
reductase
gi|347173|gb|AAC37131.1| precorrin-6x reductase [Rhodococcus erythropolis]
Length=248
Score = 205 bits (522), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 132/249 (54%), Positives = 158/249 (64%), Gaps = 6/249 (2%)
Query 1 VTRVLLLGGTAEGRALAKELH--PHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGW 58
+TR+L+LGGT E RALA L P VE VSSLAGRV +P LP+G VRIGGFGG +GL
Sbjct 1 MTRILILGGTGEARALAAALADVPGVEAVSSLAGRVRDPRLPVGDVRIGGFGGADGLAEC 60
Query 59 LREERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDP--GTAIIAVSDIEAA 116
+R +DA+VDATHPFA IT +AA G+P +VL RP W P G +D+ A
Sbjct 61 VRAHPVDAIVDATHPFAAQITRNAADAAHRRGIPLVVLRRPEWSPRPGEHWHGAADLADA 120
Query 117 DVVAEQGYSRVFLTTGRSGIAAFANSDA-WFLIRVVTAPDGTALPRRHKLVLSRGPYGYH 175
+ +R+FLT GR G+ AFA+ A WFLIR + PD A+P L+L+RGP+
Sbjct 121 AELLPDLGTRIFLTIGRQGVDAFADLQALWFLIRAIDPPD-VAMPPHSTLLLARGPFAVA 179
Query 176 DEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAA 235
DE AL+RE RID LVTKNSGG T AKLDAA ALGI V+MI RP LP VD V A
Sbjct 180 DETALMREHRIDVLVTKNSGGGQTDAKLDAARALGIPVLMIRRPPLPPATETVDDVAGAI 239
Query 236 MWVAGLPSR 244
WV L R
Sbjct 240 AWVGTLTRR 248
>gi|111017845|ref|YP_700817.1| precorrin-6A reductase [Rhodococcus jostii RHA1]
gi|110817375|gb|ABG92659.1| precorrin-6A reductase [Rhodococcus jostii RHA1]
Length=247
Score = 205 bits (522), Expect = 4e-51, Method: Compositional matrix adjust.
Identities = 128/243 (53%), Positives = 157/243 (65%), Gaps = 6/243 (2%)
Query 1 VTRVLLLGGTAEGRALAKELH--PHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGW 58
+ R+L+LGGT E RALA L P V+ VSSLAGRV +P LP+G VRIGGFGG +GL W
Sbjct 1 MARILILGGTGEARALAAALADVPGVDTVSSLAGRVRDPRLPVGDVRIGGFGGADGLDEW 60
Query 59 LREERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDP--GTAIIAVSDIEAA 116
LR +DA+VDATHPFA IT++AA G+P++VL RP W P G +D+ A
Sbjct 61 LRAHPVDAIVDATHPFAAQITSNAADAAHRRGIPHVVLRRPEWSPRPGERWHRAADLADA 120
Query 117 DVVAEQGYSRVFLTTGRSGIAAFANSDA-WFLIRVVTAPDGTALPRRHKLVLSRGPYGYH 175
+ +RVFLT GR G+ AFA A WFLIR + PD A P R L+L+RGP+
Sbjct 121 AALLPDLGTRVFLTIGRQGVDAFAGLHALWFLIRAIDPPD-VATPPRSTLLLARGPFAVT 179
Query 176 DEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAA 235
DE AL+RE RI LVTKNSGG T AKLDAA ALG+ V+MI+RP P+ VD V A
Sbjct 180 DEIALMREHRIAVLVTKNSGGGQTDAKLDAARALGVPVLMISRPPSPSETVTVDDVAGAV 239
Query 236 MWV 238
W+
Sbjct 240 EWI 242
>gi|134102397|ref|YP_001108058.1| precorrin-6A reductase [Saccharopolyspora erythraea NRRL 2338]
gi|133915020|emb|CAM05133.1| precorrin-6A reductase [Saccharopolyspora erythraea NRRL 2338]
Length=257
Score = 204 bits (519), Expect = 1e-50, Method: Compositional matrix adjust.
Identities = 122/241 (51%), Positives = 153/241 (64%), Gaps = 8/241 (3%)
Query 3 RVLLLGGTAEGRALAKEL--HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
RVL+LGGT E R LA+ L + + SLAGRV P P+G VR+GGFGG +GL WLR
Sbjct 3 RVLVLGGTGEARGLAERLAADSRLHVTYSLAGRVREPRTPVGEVRVGGFGGPDGLADWLR 62
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAII---AVSDIEAAD 117
E+++AVVDATHPFA ITA+A + G G+P L+L RP W PG S EAA
Sbjct 63 REQVEAVVDATHPFAGGITANAVEAAGRTGVPVLLLRRPGWQPGPGDDWHHVASLPEAAA 122
Query 118 VVAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDE 177
++ G +RVFLTTGR G++ FA D WFL+R V P+ LP +L+RGP+ DE
Sbjct 123 LLPGLG-NRVFLTTGRQGLSHFAALDLWFLVRTVDPPE-PPLPAHTTTLLARGPFAVEDE 180
Query 178 FALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMW 237
ALLRE RID +VTK+SGG MT AKL AA LG+ VV++ RP P A D+V A W
Sbjct 181 LALLREHRIDVVVTKDSGGTMTAAKLTAARELGLPVVVVRRPEPPTAPTA-DTVDDAVRW 239
Query 238 V 238
+
Sbjct 240 L 240
>gi|322437631|ref|YP_004219721.1| precorrin-6x reductase [Acidobacterium sp. MP5ACTX9]
gi|321165524|gb|ADW71227.1| precorrin-6x reductase [Acidobacterium sp. MP5ACTX9]
Length=258
Score = 203 bits (517), Expect = 2e-50, Method: Compositional matrix adjust.
Identities = 111/226 (50%), Positives = 144/226 (64%), Gaps = 7/226 (3%)
Query 4 VLLLGGTAEGRALAKEL--HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
VLLLGGT+E A+A L HP ++++SSLAGRV +P LP G RIGGFGGVEGL +L++
Sbjct 12 VLLLGGTSEAGAIASHLATHPDLKLISSLAGRVAHPKLPTGQTRIGGFGGVEGLITYLQQ 71
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDP--GTAIIAVSDIEAADVV 119
E+I V+DATHPFA I+ +AA C LG+P + RPPW P G V D+EAA +
Sbjct 72 EKIQIVIDATHPFAANISRNAAAACQRLGIPLISYVRPPWTPQQGDHWQDVPDLEAAAAL 131
Query 120 AEQGYSRVFLTTGRSGIAAFANS-DAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
+ Y R+FL GR +A FA WFLIR + PD LP KL+L+RGP+ DE
Sbjct 132 T-RSYHRIFLAIGRQELAPFATCIHPWFLIRTIDQPD-VPLPPNAKLILARGPFHLADEL 189
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAG 224
LL+ ID +++KNSGG T KL+AA LG+ V+M+ RP P
Sbjct 190 RLLKAHAIDCIISKNSGGPATYDKLEAARILGLPVIMVDRPTPPTN 235
>gi|291004218|ref|ZP_06562191.1| precorrin-6A reductase [Saccharopolyspora erythraea NRRL 2338]
Length=254
Score = 201 bits (511), Expect = 8e-50, Method: Compositional matrix adjust.
Identities = 120/240 (50%), Positives = 152/240 (64%), Gaps = 8/240 (3%)
Query 4 VLLLGGTAEGRALAKEL--HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
+L+LGGT E R LA+ L + + SLAGRV P P+G VR+GGFGG +GL WLR
Sbjct 1 MLVLGGTGEARGLAERLAADSRLHVTYSLAGRVREPRTPVGEVRVGGFGGPDGLADWLRR 60
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAII---AVSDIEAADV 118
E+++AVVDATHPFA ITA+A + G G+P L+L RP W PG S EAA +
Sbjct 61 EQVEAVVDATHPFAGGITANAVEAAGRTGVPVLLLRRPGWQPGPGDDWHHVASLPEAAAL 120
Query 119 VAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
+ G +RVFLTTGR G++ FA D WFL+R V P+ LP +L+RGP+ DE
Sbjct 121 LPGLG-NRVFLTTGRQGLSHFAALDLWFLVRTVDPPE-PPLPAHTTTLLARGPFAVEDEL 178
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWV 238
ALLRE RID +VTK+SGG MT AKL AA LG+ VV++ RP P A D+V A W+
Sbjct 179 ALLREHRIDVVVTKDSGGTMTAAKLTAARELGLPVVVVRRPEPPTAPTA-DTVDDAVRWL 237
>gi|299138935|ref|ZP_07032112.1| precorrin-6x reductase [Acidobacterium sp. MP5ACTX8]
gi|298599089|gb|EFI55250.1| precorrin-6x reductase [Acidobacterium sp. MP5ACTX8]
Length=269
Score = 201 bits (510), Expect = 1e-49, Method: Compositional matrix adjust.
Identities = 115/237 (49%), Positives = 146/237 (62%), Gaps = 7/237 (2%)
Query 3 RVLLLGGTAEGRALAKELHPHVE--IVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
RVL+LGGT EG LA L + ++SSLAGR+ P LP G VR+GGFGG++ L +L
Sbjct 15 RVLILGGTGEGAQLAARLAERTDFIVISSLAGRIGEPKLPQGLVRVGGFGGLDALASYLV 74
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDP--GTAIIAVSDIEAADV 118
+E I AV+DATHPFA I+ +AA C GLP + L RPPW G V D ++A
Sbjct 75 KEEIKAVIDATHPFAAKISHNAAIACSRTGLPLIALRRPPWGKIDGDLWHEVDDFQSAAS 134
Query 119 VAEQGYSRVFLTTGRSGIAAFANS-DAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDE 177
E +RVFL+ GR + AF+ DAWFLIR + P G LP H+++L RGP+ DE
Sbjct 135 FVEAKKARVFLSIGRQEVGAFSGCRDAWFLIRAIEMP-GEGLPPHHEVILQRGPFALEDE 193
Query 178 FALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRA 234
LLR+ ID LV+KNSGG T K++AA L I VVMI RPL P+ V V +V A
Sbjct 194 LHLLRKYSIDYLVSKNSGGSATYTKIEAARFLKIPVVMINRPLKPS-VPCVGTVEEA 249
>gi|284033032|ref|YP_003382963.1| precorrin-6x reductase [Kribbella flavida DSM 17836]
gi|283812325|gb|ADB34164.1| precorrin-6x reductase [Kribbella flavida DSM 17836]
Length=243
Score = 198 bits (503), Expect = 6e-49, Method: Compositional matrix adjust.
Identities = 123/240 (52%), Positives = 144/240 (60%), Gaps = 6/240 (2%)
Query 3 RVLLLGGTAEGRALAKEL--HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
+VLLLGGT E R LA+ L +E+VSSLAGR LP G VR GGFGG +GL WLR
Sbjct 2 KVLLLGGTGEARQLAEVLVAEQGLELVSSLAGRTTGARLPAGAVRQGGFGGTDGLVAWLR 61
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPW--DPGTAIIAVSDIEAADV 118
+E +DAVVDATHPFA T+T HA +G+P LVL RP W PG V A
Sbjct 62 DETVDAVVDATHPFAATMTQHAVDAARTVGVPLLVLRRPGWTASPGDDWHWVPTAAEAAA 121
Query 119 VAEQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
+ SR FLT GR G+ AFA W L R V P+ P +LVL RGPY E
Sbjct 122 LLPAIGSRAFLTIGRQGLGAFAAVGVWMLARCVDPPEPP--PDWCELVLDRGPYHLAGEI 179
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWV 238
LLR++RID LVTK+SGG MT AKL AA LG+ VV+I RP LPAGV SV + W+
Sbjct 180 DLLRDRRIDVLVTKDSGGNMTSAKLVAARQLGVPVVVIRRPPLPAGVDTAGSVDQVVGWL 239
>gi|345011367|ref|YP_004813721.1| precorrin-6x reductase [Streptomyces violaceusniger Tu 4113]
gi|344037716|gb|AEM83441.1| precorrin-6x reductase [Streptomyces violaceusniger Tu 4113]
Length=253
Score = 198 bits (503), Expect = 7e-49, Method: Compositional matrix adjust.
Identities = 118/240 (50%), Positives = 151/240 (63%), Gaps = 6/240 (2%)
Query 4 VLLLGGTAEGRALAKEL--HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
VL+LGGT E R LA EL P + + SSLAGRV P LP+G VRIGGFGG EG+ WLRE
Sbjct 10 VLILGGTTEARRLAGELADDPALRVTSSLAGRVAAPRLPVGQVRIGGFGGAEGMARWLRE 69
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAIIAVSDIEAADV--V 119
++DA++DATHPFA TI++HAA+ ++ +P L L RP W PG S AD +
Sbjct 70 HQVDALIDATHPFADTISSHAARAAADVHVPLLALRRPGWVPGPGDRWHSAGSLADAARL 129
Query 120 AEQGYSRVFLTTGRSGIAAFAN-SDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
A R+FLTTGR G+A FA+ ++ WFL+R V AP+ +P R +++L RGP+ E
Sbjct 130 APALGERIFLTTGRMGLATFAHLTEPWFLVRSVDAPE-PPVPPRMEVILDRGPFTLDGEA 188
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWV 238
LLR R+ LVTK+SG T KL AA A GI VV+I RP P GV + AA W+
Sbjct 189 ELLRRHRVQVLVTKDSGAHATAPKLTAARAAGIPVVVIRRPPAPQGVPMAQTPADAAAWL 248
>gi|297194616|ref|ZP_06912014.1| cobalt-precorrin-6x reductase [Streptomyces pristinaespiralis
ATCC 25486]
gi|297152354|gb|EFH31689.1| cobalt-precorrin-6x reductase [Streptomyces pristinaespiralis
ATCC 25486]
Length=246
Score = 196 bits (499), Expect = 2e-48, Method: Compositional matrix adjust.
Identities = 127/241 (53%), Positives = 152/241 (64%), Gaps = 8/241 (3%)
Query 4 VLLLGGTAEGRALAKELHPH--VEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
VL+LGGT EGR LA+ LH V + SSLAGRV P +P G VRIGGFGG EG+ WLRE
Sbjct 3 VLILGGTTEGRRLAETLHADATVRVTSSLAGRVATPRMPPGEVRIGGFGGAEGMARWLRE 62
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDP--GTAIIAVSDI-EAADV 118
+ AV+DATHPFA TI+ +AA E +P L L RP W P G V + EAAD
Sbjct 63 HDVGAVIDATHPFAGTISFNAALAAAEAHVPLLALRRPGWAPADGDDWHPVGSLEEAADR 122
Query 119 VAEQGYSRVFLTTGRSGIAAFAN-SDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDE 177
A G SRVFLTTGR G+A+FA+ DAWFL+R V AP+G A P R ++L RGP+ E
Sbjct 123 AAALG-SRVFLTTGRMGLASFAHIRDAWFLVRSVDAPEG-ACPPRMDVLLDRGPFTLDGE 180
Query 178 FALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMW 237
LLR RID LVTK+SGG T KL AA G+ VV++ RP +P GV AA W
Sbjct 181 RELLRRHRIDVLVTKDSGGAATAPKLTAAREAGVPVVIVHRPPVPDGVPVAGGPEEAAAW 240
Query 238 V 238
+
Sbjct 241 L 241
>gi|296139886|ref|YP_003647129.1| precorrin-6x reductase [Tsukamurella paurometabola DSM 20162]
gi|296028020|gb|ADG78790.1| precorrin-6x reductase [Tsukamurella paurometabola DSM 20162]
Length=248
Score = 195 bits (495), Expect = 6e-48, Method: Compositional matrix adjust.
Identities = 120/227 (53%), Positives = 145/227 (64%), Gaps = 11/227 (4%)
Query 3 RVLLLGGTAEGRALAKELHPHVE--IVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
RVL+LGGTAE R LA+ L + ++SSLAGRV NP LP+G RIGGFGGV+GL +L
Sbjct 7 RVLILGGTAEARELAQLLDEDDDFAVLSSLAGRVANPRLPVGQTRIGGFGGVDGLTAFL- 65
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWD--PGTAIIAVSDIEAA-- 116
ID +VDATHPFA TI+ HAA G P + RP W PG V + AA
Sbjct 66 -SGIDVLVDATHPFAATISRHAAAAAQRTGTPVFAVVRPQWSAAPGDRWTRVPTVAAAAT 124
Query 117 DVVAEQGYSRVFLTTGRSGIAAFANSDAW-FLIRVVTAPDGTALPRRHKLVLSRGPYGYH 175
++ A +G + FLTTGR + AFA DAW FLIRVV P G+ LP+RH L+ RGPY
Sbjct 125 ELSARRGGT-AFLTTGRQDVHAFAALDAWRFLIRVVDTPAGS-LPKRHTLIHDRGPYLIG 182
Query 176 DEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLP 222
E ALLRE +D LVTKNSGG + AKL+AA LG+ VVM+ RP P
Sbjct 183 AETALLRENAVDVLVTKNSGGDLVSAKLEAARMLGVEVVMVDRPPRP 229
>gi|333919696|ref|YP_004493277.1| Precorrin-6x reductase CbiJ/CobK [Amycolicicoccus subflavus DQS3-9A1]
gi|333481917|gb|AEF40477.1| Precorrin-6x reductase CbiJ/CobK [Amycolicicoccus subflavus DQS3-9A1]
Length=245
Score = 195 bits (495), Expect = 6e-48, Method: Compositional matrix adjust.
Identities = 119/238 (50%), Positives = 142/238 (60%), Gaps = 4/238 (1%)
Query 3 RVLLLGGTAEGRALAKELHPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREE 62
RVL+LGGT E RALA+ L E+VSSLAGR+ +P LP G VRIGGFGG EGL WLRE+
Sbjct 2 RVLILGGTGESRALARRLQEEYEVVSSLAGRLADPVLPDGRVRIGGFGGAEGLTAWLREQ 61
Query 63 RIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPGTAII--AVSDIEAADVVA 120
RI AV+DATHPFA IT +A P LV+ RPPW PG A ++ A A
Sbjct 62 RIGAVLDATHPFAQGITTNAVAAARAARTPLLVVHRPPWLPGREDTWEAADSMDDACARA 121
Query 121 EQGYSRVFLTTGRSGIAAFANSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFAL 180
+ VFLT GR + +F + ++ V P G LP L+ RGP+ DE +L
Sbjct 122 ARFGQPVFLTIGRQEMRSFTALRS--VVARVIDPPGWDLPGGWHLITQRGPFRASDERSL 179
Query 181 LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMWV 238
+ RI LVTKNSGG+ T AKL AA LGI VVM+ RP LP G AAV S A WV
Sbjct 180 MEHFRIGVLVTKNSGGEQTYAKLAAARELGIPVVMVRRPALPLGTAAVSSTRAAVRWV 237
>gi|294813431|ref|ZP_06772074.1| cobalt-precorrin-6x reductase [Streptomyces clavuligerus ATCC
27064]
gi|326441857|ref|ZP_08216591.1| precorrin-6X reductase [Streptomyces clavuligerus ATCC 27064]
gi|294326030|gb|EFG07673.1| cobalt-precorrin-6x reductase [Streptomyces clavuligerus ATCC
27064]
Length=258
Score = 192 bits (489), Expect = 3e-47, Method: Compositional matrix adjust.
Identities = 116/239 (49%), Positives = 147/239 (62%), Gaps = 6/239 (2%)
Query 4 VLLLGGTAEGRALAKELH--PHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
+++LGGT E R LA+ LH P + + SSLAGRV P LP G VR+GGFGG EGL WLR
Sbjct 3 IVILGGTTEARRLAELLHDTPDLRLTSSLAGRVAAPRLPPGEVRVGGFGGAEGLAAWLRA 62
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPW--DPGTAIIAVSDIEAADVV 119
+D ++DATHPFA T++ HAA+ +P L L RP W +PG V + A +
Sbjct 63 HAVDLLIDATHPFARTMSLHAARAAAATRVPLLALRRPGWVREPGDDWHPVDSLAEASAL 122
Query 120 AEQGYSRVFLTTGRSGIAAFANSDA-WFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
RVFLTTGR+G+AAFA D WFL+R V P+G +P R +++L RGPYG E
Sbjct 123 LPSLGRRVFLTTGRTGLAAFAPGDGLWFLVRSVDPPEGP-VPERCEVLLDRGPYGLDGER 181
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMW 237
LL RID +VTK+SGG T KL AA G+ VV++ RP LP GV +V AA W
Sbjct 182 ELLARHRIDVVVTKDSGGAATAPKLRAAREAGLPVVVVRRPPLPPGVVSVPDPESAAAW 240
>gi|323136566|ref|ZP_08071647.1| precorrin-6x reductase [Methylocystis sp. ATCC 49242]
gi|322397883|gb|EFY00404.1| precorrin-6x reductase [Methylocystis sp. ATCC 49242]
Length=261
Score = 192 bits (488), Expect = 3e-47, Method: Compositional matrix adjust.
Identities = 116/243 (48%), Positives = 150/243 (62%), Gaps = 8/243 (3%)
Query 3 RVLLLGGTAEGRALAKEL--HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLR 60
RVLLLGGT+EGRALA + P E V+SLAGR P P R+GGFGG EGL +L
Sbjct 20 RVLLLGGTSEGRALAGRIAADPRYEGVASLAGRTSAPMTLALPTRVGGFGGAEGLMRYLA 79
Query 61 EERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDP--GTAIIAVSDIEAADV 118
EER++ V+DATHPFA I+ +A C LG+P LV AR PW P G I V D AA
Sbjct 80 EERVERVIDATHPFAAQISENARMACEALGIPLLVYAREPWRPEQGDRWIEVEDNAAAAR 139
Query 119 VAEQGYSRVFLTTGRSGIAAFANSDAW--FLIRVVTAPDGTALPRRHKLVLSRGPYGYHD 176
+ RVFLT GR G A F + W +L+RV+ P LP + ++ +RGP+ +
Sbjct 140 ALGETPRRVFLTIGRQGAADF-RAAPWHDYLLRVIEPPRAEELPPKCEVTFARGPFTREE 198
Query 177 EFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAM 236
E AL+RE+RID +V+KNSGG +T AK++AA LG++VVMI P P GVA + A
Sbjct 199 EIALMRERRIDLVVSKNSGGALTHAKIEAARELGLTVVMIRPPERP-GVAIAHDLDAAMA 257
Query 237 WVA 239
++A
Sbjct 258 FLA 260
>gi|226306645|ref|YP_002766605.1| precorrin-6X reductase [Rhodococcus erythropolis PR4]
gi|226185762|dbj|BAH33866.1| precorrin-6X reductase [Rhodococcus erythropolis PR4]
Length=248
Score = 191 bits (485), Expect = 7e-47, Method: Compositional matrix adjust.
Identities = 114/246 (47%), Positives = 149/246 (61%), Gaps = 8/246 (3%)
Query 4 VLLLGGTAEGRALAKEL--HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
+LLLGGT EGR +A L +E+V+SLAGRV +P P G VRIGGFGG EGL WL
Sbjct 1 MLLLGGTGEGRVIASRLADSADLEVVTSLAGRVRDPRWPEGEVRIGGFGGAEGLSEWLSN 60
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPW--DPGTAIIAVSDIE-AADV 118
I AV+DATHPFA IT +A C +PY + RPPW PG + V +++ AA++
Sbjct 61 NDIRAVLDATHPFAARITKNAFDACRANSVPYAMYRRPPWREQPGDTWLPVRNLDHAAEL 120
Query 119 VAEQGYSRVFLTTGRSGIAAFAN-SDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDE 177
V G SR FLT GR G++AF D FL+R + P GT LP +L+L+RGP+ E
Sbjct 121 VPTVG-SRAFLTIGRQGVSAFDRVKDVSFLVRSIDPPSGT-LPPHSQLLLARGPFDVEAE 178
Query 178 FALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMW 237
L+R ID ++TKNSGG+ T AK+ AA L I V+++ RP +PA A D+ A W
Sbjct 179 VDLMRTHGIDVVITKNSGGEQTYAKIAAARKLSIPVIVVERPPIPATAPAFDTEAGAVDW 238
Query 238 VAGLPS 243
+ S
Sbjct 239 LTAFGS 244
>gi|305681128|ref|ZP_07403935.1| precorrin-6A reductase [Corynebacterium matruchotii ATCC 14266]
gi|305659333|gb|EFM48833.1| precorrin-6A reductase [Corynebacterium matruchotii ATCC 14266]
Length=244
Score = 191 bits (484), Expect = 1e-46, Method: Compositional matrix adjust.
Identities = 107/222 (49%), Positives = 142/222 (64%), Gaps = 5/222 (2%)
Query 5 LLLGGTAEGRALAKEL-HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLREER 63
L+LGGT EGR LA+ L + SSLAGRV P LP+G VR+GGFGG GL WL +
Sbjct 4 LILGGTHEGRELARLLVDAGWYVTSSLAGRVAAPRLPVGEVRVGGFGGPAGLTRWLMGSQ 63
Query 64 IDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPW--DPGTAIIAVSDIEAADVVAE 121
ID ++DATHPFA I+ AA+ G+P + L RP W +P I V + A +A
Sbjct 64 IDVIIDATHPFAERISYSAAEAANATGVPLIALHRPAWTPEPRDKWILVQSMAEAARIAA 123
Query 122 QGYSRVFLTTGRSGIAAFANS-DAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEFAL 180
Q + VFLT GR +A FA+ ++IR V P LP+R++++LSRGP+ DE L
Sbjct 124 QQFHHVFLTIGRQQLAPFADDPHNLYVIRAVEPPQ-VVLPKRNRVILSRGPFTVADEKKL 182
Query 181 LREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLP 222
+R+ +ID +VTKNSGG++TRAKL AA LGI+V+M+ RP LP
Sbjct 183 MRDNQIDCVVTKNSGGELTRAKLVAARELGITVIMVQRPQLP 224
>gi|336177248|ref|YP_004582623.1| precorrin-6x reductase [Frankia symbiont of Datisca glomerata]
gi|334858228|gb|AEH08702.1| precorrin-6x reductase [Frankia symbiont of Datisca glomerata]
Length=257
Score = 189 bits (481), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 122/245 (50%), Positives = 153/245 (63%), Gaps = 7/245 (2%)
Query 3 RVLLLGGTAEGRALAKELH--PHVEIVSSLAGRVPNPALPIG-PVRIGGFGGVEGLRGWL 59
RVL+LGGTAEGR L ++L P VE+V S+AGRV PALP +R+GGFGGV+GL +L
Sbjct 4 RVLVLGGTAEGRRLTEKLAELPGVEVVYSIAGRVAAPALPTAAQIRVGGFGGVDGLTSYL 63
Query 60 REERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPW--DPGTAIIAVSDIEAAD 117
R+ I AV+DATHP+A +T+ A +P LV+ RP W G V + AA
Sbjct 64 RDAGIAAVIDATHPYAALMTSAAITGSKAAAVPLLVVRRPGWPETDGDDWHRVPSLAAAA 123
Query 118 VVAEQGYSRVFLTTGRSGIAAFANSDA-WFLIRVVTAPDGTALPRRHKLVLSRGPYGYHD 176
RVFLTTGRSGIAAFA SD WFL+R + AP +P R ++L RGP+
Sbjct 124 AALGGFGERVFLTTGRSGIAAFAGSDRHWFLLRSIEAPS-PPMPARMDVLLERGPFTVEG 182
Query 177 EFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAM 236
E AL+R RID +VTKNSGG +T AKL AA LG+ V+M+ RP LP G AV +V A
Sbjct 183 ETALMRGHRIDVVVTKNSGGLLTAAKLVAARHLGLPVLMVDRPPLPPGTPAVATVEDAVA 242
Query 237 WVAGL 241
W+ L
Sbjct 243 WLTRL 247
>gi|38233822|ref|NP_939589.1| cobalt-precorrin-6x reductase [Corynebacterium diphtheriae NCTC
13129]
gi|38200083|emb|CAE49763.1| precorrin-6X reductase [Corynebacterium diphtheriae]
Length=243
Score = 189 bits (481), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 110/224 (50%), Positives = 143/224 (64%), Gaps = 5/224 (2%)
Query 3 RVLLLGGTAEGRALAKELH-PHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
R L+LGGT EGR +A LH + SSLAGRV NP LP+G VRIGGFGG GL WL
Sbjct 2 RALILGGTGEGRDVAAILHVAGWRVTSSLAGRVSNPKLPVGEVRIGGFGGPAGLTQWLLR 61
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDPG--TAIIAVSDIEAADVV 119
E ++ ++DATHPFA I+A AA+ G+P + L RP W P I V+ ++ A
Sbjct 62 EGVEVIIDATHPFAERISASAAEASRATGIPLIALHRPEWKPRPRDRWIPVTSMQEAADK 121
Query 120 AEQGYSRVFLTTGRSGIAAFA-NSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
A + Y +FLT GR +A FA ++ +++R V P ALP+RH+L+LSRGP+ E
Sbjct 122 AARDYHHIFLTIGRQQLAPFAHDAHNLYVVRAVEPPQ-VALPQRHRLILSRGPFTLESEK 180
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLP 222
L+ + +ID +VTKNSGG +T AKLDAA LGI VVM+ RP LP
Sbjct 181 KLMIDNQIDCVVTKNSGGPLTHAKLDAARDLGIDVVMVQRPQLP 224
>gi|337290706|ref|YP_004629727.1| Precorrin-6x reductase [Corynebacterium ulcerans BR-AD22]
gi|334699012|gb|AEG83808.1| Precorrin-6x reductase [Corynebacterium ulcerans BR-AD22]
Length=243
Score = 189 bits (480), Expect = 3e-46, Method: Compositional matrix adjust.
Identities = 107/224 (48%), Positives = 142/224 (64%), Gaps = 5/224 (2%)
Query 3 RVLLLGGTAEGRALAKELHPH-VEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
R L+LGGT E R +A+ L+ + SSLAGRV NP LP+G VRIGGFGG GL WL +
Sbjct 2 RALILGGTGEAREVAQLLYDAGWHVTSSLAGRVANPKLPVGEVRIGGFGGPMGLTQWLIK 61
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPW--DPGTAIIAVSDIEAADVV 119
E ++ V+DATHPFA I+ AA+ G+P + L RP W P VS + A +
Sbjct 62 EGVEVVIDATHPFAERISISAAEATRATGIPLIALHRPAWVAGPRDRWRPVSSMAEAARL 121
Query 120 AEQGYSRVFLTTGRSGIAAFA-NSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
A + Y +FLT GR +A FA + ++IR V P LP+RH+L++SRGP+ DE
Sbjct 122 AARDYHHIFLTIGRQQLAPFAEDPHNLYVIRTVEPPQ-VILPQRHRLIMSRGPFTVADEK 180
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLP 222
L+ + +ID +VTKNSGG +T AKLDAA LGI V+M+ RP+LP
Sbjct 181 KLMVDNQIDCVVTKNSGGPLTSAKLDAARELGIDVIMVQRPVLP 224
>gi|334696819|gb|AEG81616.1| Precorrin-6x reductase [Corynebacterium ulcerans 809]
Length=243
Score = 189 bits (479), Expect = 4e-46, Method: Compositional matrix adjust.
Identities = 106/224 (48%), Positives = 142/224 (64%), Gaps = 5/224 (2%)
Query 3 RVLLLGGTAEGRALAKELHPH-VEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
R L+LGGT E R +A+ L+ + SSLAGRV NP LP+G VRIGGFGG GL WL +
Sbjct 2 RALILGGTGEAREVAQLLYDAGWHVTSSLAGRVANPKLPVGEVRIGGFGGPMGLTQWLIK 61
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPW--DPGTAIIAVSDIEAADVV 119
E ++ V+DATHPFA I+ AA+ G+P + L RP W P VS + A +
Sbjct 62 EGVEVVIDATHPFAERISISAAEATRATGIPLIALHRPAWVAGPRDRWRPVSSMAEAARL 121
Query 120 AEQGYSRVFLTTGRSGIAAFA-NSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
A + Y +FLT GR +A FA + +++R V P LP+RH+L++SRGP+ DE
Sbjct 122 AARDYHHIFLTIGRQQLAPFAEDPHNLYVVRTVEPPQ-VPLPQRHRLIMSRGPFTVADEK 180
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLP 222
L+ + +ID +VTKNSGG +T AKLDAA LGI V+M+ RP+LP
Sbjct 181 KLMVDNQIDCVVTKNSGGPLTSAKLDAARELGIDVIMVQRPVLP 224
>gi|300858444|ref|YP_003783427.1| precorrin-6x reductase [Corynebacterium pseudotuberculosis FRC41]
gi|300685898|gb|ADK28820.1| Precorrin-6x reductase [Corynebacterium pseudotuberculosis FRC41]
gi|308276397|gb|ADO26296.1| cobalt-precorrin-6x reductase [Corynebacterium pseudotuberculosis
I19]
Length=243
Score = 188 bits (477), Expect = 7e-46, Method: Compositional matrix adjust.
Identities = 105/224 (47%), Positives = 140/224 (63%), Gaps = 5/224 (2%)
Query 3 RVLLLGGTAEGRALAKELHPH-VEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
R L+LGGT E R +A+ L+ + SSLAGRV NP LP+G VRIGGFGG GL WL +
Sbjct 2 RALILGGTGEAREVAQMLYDAGWHVTSSLAGRVANPKLPVGEVRIGGFGGPMGLTQWLIK 61
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWD--PGTAIIAVSDIEAADVV 119
E ++ V+DATHPFA I+ A + G+P + L RP W P VS + A +
Sbjct 62 EGVEVVIDATHPFAERISISAVEATRATGIPLIALHRPAWTAAPRDRWRTVSSVAQAASL 121
Query 120 AEQGYSRVFLTTGRSGIAAFA-NSDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDEF 178
A + Y +FLT GR +A FA + +++R V P LP RH+L++SRGP+ DE
Sbjct 122 AARDYHHIFLTIGRQQLAPFAEDPHNLYVVRTVEPPQ-VPLPPRHRLIMSRGPFTVTDEK 180
Query 179 ALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLP 222
L+ + +ID +VTKNSGG +T AKLDAA LG+ V+MI RP+LP
Sbjct 181 KLMVDNQIDCVVTKNSGGPLTSAKLDAARELGVDVIMIQRPVLP 224
>gi|226359978|ref|YP_002777756.1| precorrin-6X reductase [Rhodococcus opacus B4]
gi|226238463|dbj|BAH48811.1| precorrin-6X reductase [Rhodococcus opacus B4]
Length=246
Score = 187 bits (476), Expect = 9e-46, Method: Compositional matrix adjust.
Identities = 132/247 (54%), Positives = 158/247 (64%), Gaps = 8/247 (3%)
Query 1 VTRVLLLGGTAEGRALAKELH--PHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGW 58
++R+L+LGGT E RALA L P VE VSSLAGRV +P LP G VRIGGFGG GL W
Sbjct 1 MSRILILGGTGEARALAAALADVPGVEAVSSLAGRVRDPRLPAGEVRIGGFGGAAGLAEW 60
Query 59 LREERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPW--DPGTAIIAVSDI-EA 115
L +DA+VDATHPFA IT +AA G+P +VL RP W PG D+ A
Sbjct 61 LCAHPVDAIVDATHPFAAQITRNAADAAHRRGIPLVVLRRPEWAPRPGEHWHTAPDLARA 120
Query 116 ADVVAEQGYSRVFLTTGRSGIAAFANSDA-WFLIRVVTAPDGTALPRRHKLVLSRGPYGY 174
AD++ G +R+FLT GR G+ FA A WFLIR + PD A+P + L+L+RGP+
Sbjct 121 ADLLPGLG-TRIFLTIGRQGVDVFAGLHALWFLIRAIDPPD-VAMPPQSTLLLARGPFAV 178
Query 175 HDEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRA 234
E AL+RE RID LVTKNSGG T AKLDAA ALGI V+MI RP LP+ A VD V A
Sbjct 179 AGETALMREHRIDVLVTKNSGGGQTDAKLDAARALGIPVLMIRRPPLPSATATVDDVAGA 238
Query 235 AMWVAGL 241
W+ L
Sbjct 239 VAWIGAL 245
>gi|317123948|ref|YP_004098060.1| precorrin-6A reductase [Intrasporangium calvum DSM 43043]
gi|315588036|gb|ADU47333.1| precorrin-6A reductase [Intrasporangium calvum DSM 43043]
Length=245
Score = 187 bits (476), Expect = 9e-46, Method: Compositional matrix adjust.
Identities = 119/244 (49%), Positives = 158/244 (65%), Gaps = 6/244 (2%)
Query 3 RVLLLGGTAEGRALAKEL-HPHVEIVSSLAGRVPNPALPIGPVRIGGFGGVEGLRGWLRE 61
R+LLLGGT E R LA L ++VSSLAGRV PALP+G VR GGFGGV+GL G LR+
Sbjct 2 RILLLGGTGEARTLAARLVDAGHDVVSSLAGRVSRPALPVGSVRTGGFGGVDGLVGHLRD 61
Query 62 ERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDP---GTAIIAVSDIEAADV 118
+ AVVDATHPFA ITA+AA+ C GLP L L RP W+ V D+E+A
Sbjct 62 GGVGAVVDATHPFAEQITANAAEACAVTGLPLLRLQRPGWERHRLAERFHWVDDVESARP 121
Query 119 VAEQGYSRVFLTTGRSGIAAFAN-SDAWFLIRVVTAPDGTALPRRHKLVLSRGPYGYHDE 177
AE R F+TTGR + FA +D + L+RVV P+ + +P +++ +RGPY Y E
Sbjct 122 AAEGLGVRPFVTTGRQQLETFAAWTDRYVLVRVVDPPEWS-VPHTWEVLRARGPYTYAAE 180
Query 178 FALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPLLPAGVAAVDSVHRAAMW 237
AL+ ++R+D ++TK+SGG +T AKL+AA ALG+ VV++ RP LP G+ V++ A W
Sbjct 181 LALMEDRRVDVVLTKDSGGALTEAKLEAATALGVPVVVVRRPPLPGGLGVVEAPDAALAW 240
Query 238 VAGL 241
V L
Sbjct 241 VRSL 244
>gi|336115957|ref|YP_004570723.1| precorrin-6X reductase [Microlunatus phosphovorus NM-1]
gi|334683735|dbj|BAK33320.1| precorrin-6X reductase [Microlunatus phosphovorus NM-1]
Length=261
Score = 185 bits (470), Expect = 4e-45, Method: Compositional matrix adjust.
Identities = 118/228 (52%), Positives = 142/228 (63%), Gaps = 13/228 (5%)
Query 4 VLLLGGTAEGRALAKELHPH-VEIVSSLAGRVPNPALPIGPVRIGGFG-----GVEGLRG 57
VL+LGGTAE R+LA EL +VSSLAGRV +PALP+G VR+GGF GV GL
Sbjct 13 VLILGGTAEARSLASELMAAGRNVVSSLAGRVRDPALPVGEVRVGGFSIGKLDGVTGLAA 72
Query 58 WLREERIDAVVDATHPFAVTITAHAAQVCGELGLPYLVLARPPWDP---GTAIIAVSDIE 114
+L + +I AVVDATHPFA TI+A+A C G P L L RP W + V IE
Sbjct 73 FLVDHQITAVVDATHPFAATISANAVAACARTGTPLLRLERPGWRTHPDADRWLWVDSIE 132
Query 115 AADVVAEQGYSRVFLTTGRSGIAAFAN--SDAWFLIRVVTAPDGTALPRRHKLVLSRGPY 172
V A Y+R FLTTGR +A FA +D RVV P+ T LP R +L+ SRGPY
Sbjct 133 QT-VQAGAAYARPFLTTGRQSLAVFAEGWADKQVTTRVVDPPECT-LPARWQLIRSRGPY 190
Query 173 GYHDEFALLREQRIDALVTKNSGGKMTRAKLDAAAALGISVVMIARPL 220
Y DE AL+ + D LVTK+SGG T AKLDAA LGI V++IARP+
Sbjct 191 AYADEHALMSKAGTDLLVTKDSGGTHTAAKLDAARDLGIQVLVIARPV 238
Lambda K H
0.321 0.138 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 340053351120
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40