BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2129c Length=293 Score E Sequences producing significant alignments: (Bits) Value gi|15609266|ref|NP_216645.1| short chain dehydrogenase [Mycobact... 592 2e-167 gi|15841620|ref|NP_336657.1| short chain dehydrogenase [Mycobact... 591 6e-167 gi|253798808|ref|YP_003031809.1| oxidoreductase [Mycobacterium t... 590 7e-167 gi|254551163|ref|ZP_05141610.1| short chain dehydrogenase [Mycob... 590 1e-166 gi|306776377|ref|ZP_07414714.1| oxidoreductase [Mycobacterium tu... 588 2e-166 gi|289570242|ref|ZP_06450469.1| oxidoreductase [Mycobacterium tu... 506 2e-141 gi|240171406|ref|ZP_04750065.1| short chain dehydrogenase [Mycob... 483 2e-134 gi|183983108|ref|YP_001851399.1| dehydrogenase [Mycobacterium ma... 481 8e-134 gi|118617862|ref|YP_906194.1| short chain dehydrogenase [Mycobac... 476 1e-132 gi|296165215|ref|ZP_06847762.1| short-chain dehydrogenase/reduct... 448 4e-124 gi|342859831|ref|ZP_08716484.1| short chain dehydrogenase [Mycob... 436 2e-120 gi|254775047|ref|ZP_05216563.1| short chain dehydrogenase [Mycob... 424 7e-117 gi|118463268|ref|YP_881577.1| short chain dehydrogenase [Mycobac... 424 7e-117 gi|336462013|gb|EGO40862.1| short-chain alcohol dehydrogenase [M... 424 8e-117 gi|41407959|ref|NP_960795.1| short chain dehydrogenase [Mycobact... 424 1e-116 gi|254819670|ref|ZP_05224671.1| short chain dehydrogenase [Mycob... 412 2e-113 gi|333990413|ref|YP_004523027.1| dehydrogenase [Mycobacterium sp... 409 3e-112 gi|108800118|ref|YP_640315.1| short chain dehydrogenase [Mycobac... 398 7e-109 gi|126435743|ref|YP_001071434.1| short chain dehydrogenase [Myco... 397 9e-109 gi|118472164|ref|YP_888467.1| short chain dehydrogenase [Mycobac... 368 7e-100 gi|145223637|ref|YP_001134315.1| short chain dehydrogenase [Myco... 363 1e-98 gi|120404449|ref|YP_954278.1| short chain dehydrogenase [Mycobac... 362 3e-98 gi|169629203|ref|YP_001702852.1| short chain dehydrogenase [Myco... 357 2e-96 gi|226362057|ref|YP_002779835.1| short chain dehydrogenase [Rhod... 346 2e-93 gi|111019909|ref|YP_702881.1| short chain dehydrogenase [Rhodoco... 339 4e-91 gi|134097771|ref|YP_001103432.1| short chain dehydrogenase [Sacc... 286 2e-75 gi|289745402|ref|ZP_06504780.1| hypothetical oxidoreductase [Myc... 271 1e-70 gi|315506284|ref|YP_004085171.1| short-chain dehydrogenase/reduc... 243 2e-62 gi|302867310|ref|YP_003835947.1| short-chain dehydrogenase/reduc... 243 2e-62 gi|333921848|ref|YP_004495429.1| oxidoreductase, short-chain deh... 242 5e-62 gi|311742026|ref|ZP_07715836.1| short-chain dehydrogenase/reduct... 220 2e-55 gi|297204820|ref|ZP_06922217.1| 2-hydroxycyclohexanecarboxyl-CoA... 218 1e-54 gi|72162101|ref|YP_289758.1| short chain dehydrogenase [Thermobi... 207 2e-51 gi|337766161|emb|CCB74872.1| Short chain dehydrogenase [Streptom... 203 3e-50 gi|297200302|ref|ZP_06917699.1| 2-hydroxycyclohexanecarboxyl-CoA... 201 1e-49 gi|291439112|ref|ZP_06578502.1| short chain dehydrogenase [Strep... 200 2e-49 gi|297193887|ref|ZP_06911285.1| short chain dehydrogenase [Strep... 199 3e-49 gi|289771101|ref|ZP_06530479.1| short chain dehydrogenase [Strep... 198 9e-49 gi|21221607|ref|NP_627386.1| short chain dehydrogenase [Streptom... 198 1e-48 gi|294629845|ref|ZP_06708405.1| 3-oxoacyl-[acyl carrier protein]... 197 1e-48 gi|257057765|ref|YP_003135597.1| short-chain alcohol dehydrogena... 197 2e-48 gi|254388841|ref|ZP_05004073.1| short chain dehydrogenase [Strep... 196 3e-48 gi|320010287|gb|ADW05137.1| short-chain dehydrogenase/reductase ... 196 3e-48 gi|345000203|ref|YP_004803057.1| short-chain dehydrogenase/reduc... 195 8e-48 gi|300790913|ref|YP_003771204.1| short-chain dehydrogenase [Amyc... 194 2e-47 gi|291453531|ref|ZP_06592921.1| short chain dehydrogenase [Strep... 194 2e-47 gi|311899614|dbj|BAJ32022.1| putative oxidoreductase [Kitasatosp... 193 3e-47 gi|295838285|ref|ZP_06825218.1| short-chain dehydrogenase/reduct... 192 4e-47 gi|302531114|ref|ZP_07283456.1| 2-hydroxycyclohexanecarboxyl-CoA... 191 9e-47 gi|302560177|ref|ZP_07312519.1| 3-oxoacyl-[acyl carrier protein]... 191 1e-46 >gi|15609266|ref|NP_216645.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|31793309|ref|NP_855802.1| short chain dehydrogenase [Mycobacterium bovis AF2122/97] gi|121638011|ref|YP_978235.1| short chain dehydrogenase [Mycobacterium bovis BCG str. Pasteur 1173P2] 59 more sequence titles Length=293 Score = 592 bits (1526), Expect = 2e-167, Method: Compositional matrix adjust. Identities = 293/293 (100%), Positives = 293/293 (100%), Gaps = 0/293 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV Sbjct 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT Sbjct 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS Sbjct 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG Sbjct 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS Sbjct 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 >gi|15841620|ref|NP_336657.1| short chain dehydrogenase [Mycobacterium tuberculosis CDC1551] gi|13881871|gb|AAK46471.1| oxidoreductase, short-chain dehydrogenase/reductase family [Mycobacterium tuberculosis CDC1551] Length=310 Score = 591 bits (1523), Expect = 6e-167, Method: Compositional matrix adjust. Identities = 293/293 (100%), Positives = 293/293 (100%), Gaps = 0/293 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV Sbjct 18 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 77 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT Sbjct 78 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 137 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS Sbjct 138 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 197 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG Sbjct 198 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 257 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS Sbjct 258 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 310 >gi|253798808|ref|YP_003031809.1| oxidoreductase [Mycobacterium tuberculosis KZN 1435] gi|289554085|ref|ZP_06443295.1| oxidoreductase [Mycobacterium tuberculosis KZN 605] gi|297634715|ref|ZP_06952495.1| short chain dehydrogenase [Mycobacterium tuberculosis KZN 4207] gi|297731704|ref|ZP_06960822.1| short chain dehydrogenase [Mycobacterium tuberculosis KZN R506] gi|313659039|ref|ZP_07815919.1| short chain dehydrogenase [Mycobacterium tuberculosis KZN V2475] gi|253320311|gb|ACT24914.1| oxidoreductase [Mycobacterium tuberculosis KZN 1435] gi|289438717|gb|EFD21210.1| oxidoreductase [Mycobacterium tuberculosis KZN 605] gi|328458570|gb|AEB03993.1| oxidoreductase [Mycobacterium tuberculosis KZN 4207] Length=293 Score = 590 bits (1522), Expect = 7e-167, Method: Compositional matrix adjust. Identities = 292/293 (99%), Positives = 293/293 (100%), Gaps = 0/293 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV Sbjct 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT Sbjct 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS Sbjct 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSV+KCAAAFVNGIEGRKDRVYCPG Sbjct 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVSKCAAAFVNGIEGRKDRVYCPG 240 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS Sbjct 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 >gi|254551163|ref|ZP_05141610.1| short chain dehydrogenase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=293 Score = 590 bits (1520), Expect = 1e-166, Method: Compositional matrix adjust. Identities = 292/293 (99%), Positives = 292/293 (99%), Gaps = 0/293 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV Sbjct 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT Sbjct 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRL VAHLGVSVGS Sbjct 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLAVAHLGVSVGS 180 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG Sbjct 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS Sbjct 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 >gi|306776377|ref|ZP_07414714.1| oxidoreductase [Mycobacterium tuberculosis SUMu001] gi|306972489|ref|ZP_07485150.1| oxidoreductase [Mycobacterium tuberculosis SUMu010] gi|307080199|ref|ZP_07489369.1| oxidoreductase [Mycobacterium tuberculosis SUMu011] gi|308215166|gb|EFO74565.1| oxidoreductase [Mycobacterium tuberculosis SUMu001] gi|308358044|gb|EFP46895.1| oxidoreductase [Mycobacterium tuberculosis SUMu010] gi|308361984|gb|EFP50835.1| oxidoreductase [Mycobacterium tuberculosis SUMu011] Length=293 Score = 588 bits (1517), Expect = 2e-166, Method: Compositional matrix adjust. Identities = 292/293 (99%), Positives = 292/293 (99%), Gaps = 0/293 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV Sbjct 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT Sbjct 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS Sbjct 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRV CPG Sbjct 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVSCPG 240 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS Sbjct 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 >gi|289570242|ref|ZP_06450469.1| oxidoreductase [Mycobacterium tuberculosis T17] gi|289543996|gb|EFD47644.1| oxidoreductase [Mycobacterium tuberculosis T17] Length=249 Score = 506 bits (1302), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 248/249 (99%), Positives = 249/249 (100%), Gaps = 0/249 (0%) Query 45 VMGAELGGDDRLLTVVADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQ 104 +MGAELGGDDRLLTVVADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQ Sbjct 1 MMGAELGGDDRLLTVVADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQ 60 Query 105 AFRRVLDVNLLGNFHTVRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFA 164 AFRRVLDVNLLGNFHTVRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFA Sbjct 61 AFRRVLDVNLLGNFHTVRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFA 120 Query 165 NALRLEVAHLGVSVGSAHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAA 224 NALRLEVAHLGVSVGSAHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAA Sbjct 121 NALRLEVAHLGVSVGSAHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAA 180 Query 225 FVNGIEGRKDRVYCPGWVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFAS 284 FVNGIEGRKDRVYCPGWVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFAS Sbjct 181 FVNGIEGRKDRVYCPGWVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFAS 240 Query 285 AYTESLENS 293 AYTESLENS Sbjct 241 AYTESLENS 249 >gi|240171406|ref|ZP_04750065.1| short chain dehydrogenase [Mycobacterium kansasii ATCC 12478] Length=297 Score = 483 bits (1242), Expect = 2e-134, Method: Compositional matrix adjust. Identities = 235/293 (81%), Positives = 262/293 (90%), Gaps = 0/293 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTS+Q KVVFITG ARGIGAEVARRLHNKGAKLVLTD+ +EL + AELGGD R+LTVV Sbjct 1 MTSVQDKVVFITGGARGIGAEVARRLHNKGAKLVLTDIGTAELTTIAAELGGDGRVLTVV 60 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDL AMQAAA+ A+E+FGGIDVV+ANAGIASYGSVL+VDP+AF+RVLDVN+LG FHT Sbjct 61 ADVRDLSAMQAAADLAIEKFGGIDVVIANAGIASYGSVLQVDPEAFKRVLDVNVLGVFHT 120 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPA+I+RRGYVLIVSSLAAFAA PG+APYN +KAG E FANALRLEVAH GVSVGS Sbjct 121 VRATLPAVIERRGYVLIVSSLAAFAASPGLAPYNATKAGVEIFANALRLEVAHHGVSVGS 180 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDTALVRDTKADLPAF ELL RLPWPLN TTSVNKCAAAFV GIEGRK R++CP Sbjct 181 AHMSWIDTALVRDTKADLPAFDELLRRLPWPLNLTTSVNKCAAAFVKGIEGRKTRIFCPR 240 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 WV LFRWLKP+LST VG+RPIR A+L+P+MDAE AALGR SAYT +L+N+ Sbjct 241 WVGLFRWLKPVLSTSVGERPIRKITAELLPRMDAEAAALGRSTSAYTHALDNA 293 >gi|183983108|ref|YP_001851399.1| dehydrogenase [Mycobacterium marinum M] gi|183176434|gb|ACC41544.1| dehydrogenase [Mycobacterium marinum M] Length=293 Score = 481 bits (1237), Expect = 8e-134, Method: Compositional matrix adjust. Identities = 233/292 (80%), Positives = 262/292 (90%), Gaps = 0/292 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTS+Q KVVFITG ARGIGAEVARRLHN GAKLVL DLS++ELA + AELGGDDR+LTVV Sbjct 1 MTSVQDKVVFITGGARGIGAEVARRLHNMGAKLVLADLSEAELATIAAELGGDDRVLTVV 60 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDLPAM+AAA+ AVE+FGGID+V+ANAGIASYGSVL+VDP+AF+RVLDVN++G FHT Sbjct 61 ADVRDLPAMEAAADQAVEKFGGIDIVMANAGIASYGSVLQVDPEAFKRVLDVNVMGVFHT 120 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPA+I+RRGYVLIVSSLAA+AA PG+APYN SKA E FANALRLEVA GVSVGS Sbjct 121 VRATLPAVIERRGYVLIVSSLAAYAASPGLAPYNASKAAVEIFANALRLEVADRGVSVGS 180 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDTALVRDTK DLPAFAELL+RLPWPLNKTTSVNKCAAAFV GIEGRK R+YCP Sbjct 181 AHMSWIDTALVRDTKGDLPAFAELLSRLPWPLNKTTSVNKCAAAFVKGIEGRKTRIYCPD 240 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 WV LFRWLKP+LST +G+ P+R A+L+P+MDAEVAALGR SAY + LE Sbjct 241 WVGLFRWLKPVLSTPLGELPVRKATAELLPKMDAEVAALGRSTSAYNQGLEK 292 >gi|118617862|ref|YP_906194.1| short chain dehydrogenase [Mycobacterium ulcerans Agy99] gi|118569972|gb|ABL04723.1| dehydrogenase [Mycobacterium ulcerans Agy99] Length=293 Score = 476 bits (1226), Expect = 1e-132, Method: Compositional matrix adjust. Identities = 231/292 (80%), Positives = 261/292 (90%), Gaps = 0/292 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTS+Q KVVFITG ARGIGAEVARRLHN GAKLVLTDLS++ELA + AELG DDR+LTVV Sbjct 1 MTSVQDKVVFITGGARGIGAEVARRLHNMGAKLVLTDLSEAELATIAAELGRDDRVLTVV 60 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDLPAM+AAA+ AVE+FGGID+V+ANAGIASYGSVL+VDP+AF+RVLDVN++G FHT Sbjct 61 ADVRDLPAMEAAADQAVEKFGGIDIVMANAGIASYGSVLQVDPEAFKRVLDVNVMGVFHT 120 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPA+I+RRGYVLIVSSLAA+AA PG+APYN SKA E FANALRLEVA GVSVGS Sbjct 121 VRATLPAVIERRGYVLIVSSLAAYAASPGLAPYNASKAAVEIFANALRLEVADRGVSVGS 180 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDTALVRDTK DLPAFAELL+RLPWPLNKTTSVNKCAAAF+ GIEGRK R+YCP Sbjct 181 AHMSWIDTALVRDTKGDLPAFAELLSRLPWPLNKTTSVNKCAAAFIKGIEGRKTRIYCPD 240 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 WV LFRWLKP LST +G+ P+R A+L+P+MDAE+AALGR SAY + LE Sbjct 241 WVGLFRWLKPALSTPLGELPVRKATAELLPKMDAEMAALGRATSAYNQGLEK 292 >gi|296165215|ref|ZP_06847762.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899404|gb|EFG78863.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=293 Score = 448 bits (1153), Expect = 4e-124, Method: Compositional matrix adjust. Identities = 221/290 (77%), Positives = 253/290 (88%), Gaps = 1/290 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSLQ +VVFITG ARGIGAEVARRL KGAKLVLTDL+ +EL + AELG +D +LT V Sbjct 1 MTSLQDQVVFITGGARGIGAEVARRLRKKGAKLVLTDLNDAELTALAAELG-EDHVLTAV 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDLPAMQAAA AVERFGGIDVVVANAGIASYGSVL+VDP+AF+RVLD+NLLG F+T Sbjct 60 ADVRDLPAMQAAATRAVERFGGIDVVVANAGIASYGSVLQVDPEAFKRVLDINLLGVFNT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPA+I+RRGYVLIVSSLAA+AA PG+APYN SKAG E ANALRLEVAH GV+VGS Sbjct 120 VRATLPAVIERRGYVLIVSSLAAYAACPGLAPYNASKAGVEILANALRLEVAHRGVTVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 +HMSWIDTALVRD++ADLPAF +LL+ PWPLNKTT+V KCA AFV GIEGR+ RVYCPG Sbjct 180 SHMSWIDTALVRDSEADLPAFGKLLSSFPWPLNKTTTVAKCADAFVKGIEGRRSRVYCPG 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESL 290 WVALFRW+KP+LST VG+ P+ A+L+PQ+DA+VAALGR SAY + L Sbjct 240 WVALFRWIKPVLSTPVGELPLHKPTAELLPQLDAQVAALGRSTSAYNQDL 289 >gi|342859831|ref|ZP_08716484.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] gi|342132963|gb|EGT86183.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] Length=292 Score = 436 bits (1121), Expect = 2e-120, Method: Compositional matrix adjust. Identities = 217/293 (75%), Positives = 252/293 (87%), Gaps = 1/293 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSL+ KVVFITG ARGIGAE ARRL KGAKLVLTDL++++L + AELG ++R+LTVV Sbjct 1 MTSLRDKVVFITGGARGIGAETARRLSAKGAKLVLTDLNEADLKALAAELG-EERVLTVV 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDL AM+AAA AVERFGGIDVVVANAGIASYGSVL+VDP AF+RVLD+N+LG FHT Sbjct 60 ADVRDLSAMEAAAGRAVERFGGIDVVVANAGIASYGSVLQVDPDAFKRVLDINVLGVFHT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPALI+RRGYVLIVSSLAA+ A PG+APYN SKAG E ANALRLEVAH GV+VGS Sbjct 120 VRATLPALIERRGYVLIVSSLAAYTACPGLAPYNASKAGVELLANALRLEVAHRGVTVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWI+TALVRDT++DLPAF LLA PWPL+KTT+V+KCAAAFV GIE R+ RVYCP Sbjct 180 AHMSWINTALVRDTQSDLPAFNALLASFPWPLSKTTTVDKCAAAFVKGIERRRTRVYCPR 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 WVALFRW+KP+LS+ VG+ P+ + A+L+PQ+DA+VAALGR SAY L S Sbjct 240 WVALFRWVKPVLSSPVGEMPLHKSTAELLPQLDAQVAALGRSTSAYNRDLGTS 292 >gi|254775047|ref|ZP_05216563.1| short chain dehydrogenase [Mycobacterium avium subsp. avium ATCC 25291] Length=299 Score = 424 bits (1091), Expect = 7e-117, Method: Compositional matrix adjust. Identities = 212/285 (75%), Positives = 247/285 (87%), Gaps = 1/285 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSL+ KVVFITG ARGIGAEVARRL+ KGA+LVLTDL+ +EL + AELG ++R+LT V Sbjct 1 MTSLRDKVVFITGGARGIGAEVARRLNAKGARLVLTDLNDAELTSLAAELG-EERVLTAV 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDL AMQAAA+ AVERFGGIDVV+ANAGIASYGSV +VDP AFRRVLD+N+LG FHT Sbjct 60 ADVRDLSAMQAAADRAVERFGGIDVVLANAGIASYGSVAQVDPDAFRRVLDINVLGVFHT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPA+I+RRGYVLIVSSLAA+AA PG+APYN SKAG E ANALRLEVA GV VGS Sbjct 120 VRATLPAVIERRGYVLIVSSLAAYAACPGLAPYNASKAGVEMLANALRLEVARHGVKVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWI+TALVRDT+ DLPAF LLA LPWPLNKTT+V+KCAAAFV GI+ R+ R+YCP Sbjct 180 AHMSWINTALVRDTQNDLPAFDRLLASLPWPLNKTTTVDKCAAAFVKGIQRRRTRIYCPR 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASA 285 WVALFRW KP+LS+R+G+ P+ + A+L+P +DA+VAALGR SA Sbjct 240 WVALFRWAKPVLSSRLGEMPLHSPTAELLPALDAQVAALGRSMSA 284 >gi|118463268|ref|YP_881577.1| short chain dehydrogenase [Mycobacterium avium 104] gi|118164555|gb|ABK65452.1| short chain dehydrogenase [Mycobacterium avium 104] Length=299 Score = 424 bits (1090), Expect = 7e-117, Method: Compositional matrix adjust. Identities = 212/285 (75%), Positives = 247/285 (87%), Gaps = 1/285 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSL+ KVVFITG ARGIGAEVARRL+ KGA+LVLTDL+ +EL + AELG ++R+LT V Sbjct 1 MTSLRDKVVFITGGARGIGAEVARRLNAKGARLVLTDLNDAELTSLAAELG-EERVLTAV 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDL AMQAAA+ AVERFGGIDVV+ANAGIASYGSV +VDP AFRRVLD+N+LG FHT Sbjct 60 ADVRDLSAMQAAADRAVERFGGIDVVLANAGIASYGSVAQVDPDAFRRVLDINVLGVFHT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPA+I+RRGYVLIVSSLAA+AA PG+APYN SKAG E ANALRLEVA GV VGS Sbjct 120 VRATLPAVIERRGYVLIVSSLAAYAACPGLAPYNASKAGVEMLANALRLEVARHGVKVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWI+TALVRDT+ DLPAF LLA LPWPLNKTT+V+KCAAAFV GI+ R+ R+YCP Sbjct 180 AHMSWINTALVRDTQNDLPAFDRLLASLPWPLNKTTTVDKCAAAFVKGIQRRRTRIYCPR 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASA 285 WVALFRW KP+LS+R+G+ P+ + A+L+P +DA+VAALGR SA Sbjct 240 WVALFRWAKPVLSSRLGEMPLHSPTAELLPALDAQVAALGRSMSA 284 >gi|336462013|gb|EGO40862.1| short-chain alcohol dehydrogenase [Mycobacterium avium subsp. paratuberculosis S397] Length=299 Score = 424 bits (1090), Expect = 8e-117, Method: Compositional matrix adjust. Identities = 212/285 (75%), Positives = 247/285 (87%), Gaps = 1/285 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSL+ KVVFITG ARGIGAEVARRL+ KGA+LVLTDL+ +EL + AELG ++R+LT V Sbjct 1 MTSLRDKVVFITGGARGIGAEVARRLNAKGARLVLTDLNDAELTSLAAELG-EERVLTAV 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDL AMQAAA+ AVERFGGIDVV+ANAGIASYGSV +VDP AFRRVLD+N+LG FHT Sbjct 60 ADVRDLSAMQAAADRAVERFGGIDVVLANAGIASYGSVAQVDPDAFRRVLDINVLGVFHT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPA+I+RRGYVLIVSSLAA+AA PG+APYN SKAG E ANALRLEVA GV VGS Sbjct 120 VRATLPAVIERRGYVLIVSSLAAYAACPGLAPYNASKAGVEMLANALRLEVARHGVKVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWI+TALVRDT+ DLPAF LLA LPWPLNKTT+V+KCAAAFV GI+ R+ R+YCP Sbjct 180 AHMSWINTALVRDTQNDLPAFDRLLASLPWPLNKTTTVDKCAAAFVKGIQRRRARIYCPR 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASA 285 WVALFRW KP+LS+R+G+ P+ + A+L+P +DA+VAALGR SA Sbjct 240 WVALFRWAKPVLSSRLGEMPLHSPTAELLPALDAQVAALGRSMSA 284 >gi|41407959|ref|NP_960795.1| short chain dehydrogenase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396313|gb|AAS04178.1| hypothetical protein MAP_1861c [Mycobacterium avium subsp. paratuberculosis K-10] Length=299 Score = 424 bits (1089), Expect = 1e-116, Method: Compositional matrix adjust. Identities = 212/285 (75%), Positives = 246/285 (87%), Gaps = 1/285 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSL+ KVVFITG ARGIGAEVARRL KGA+LVLTDL+ +EL + AELG ++R+LT V Sbjct 1 MTSLRDKVVFITGGARGIGAEVARRLKAKGARLVLTDLNDAELTSLAAELG-EERVLTAV 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDL AMQAAA+ AVERFGGIDVV+ANAGIASYGSV +VDP AFRRVLD+N+LG FHT Sbjct 60 ADVRDLSAMQAAADRAVERFGGIDVVLANAGIASYGSVAQVDPDAFRRVLDINVLGVFHT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPA+I+RRGYVLIVSSLAA+AA PG+APYN SKAG E ANALRLEVA GV VGS Sbjct 120 VRATLPAVIERRGYVLIVSSLAAYAACPGLAPYNASKAGVEMLANALRLEVARHGVKVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWI+TALVRDT+ DLPAF LLA LPWPLNKTT+V+KCAAAFV GI+ R+ R+YCP Sbjct 180 AHMSWINTALVRDTQNDLPAFDRLLASLPWPLNKTTTVDKCAAAFVKGIQRRRARIYCPR 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASA 285 WVALFRW KP+LS+R+G+ P+ + A+L+P +DA+VAALGR SA Sbjct 240 WVALFRWAKPVLSSRLGEMPLHSPTAELLPALDAQVAALGRSMSA 284 >gi|254819670|ref|ZP_05224671.1| short chain dehydrogenase [Mycobacterium intracellulare ATCC 13950] Length=292 Score = 412 bits (1060), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 212/293 (73%), Positives = 245/293 (84%), Gaps = 1/293 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSL+ +VVFITG ARGIGAEVARRL KGAKLVLTDL++++L + ELG +DR+LT V Sbjct 1 MTSLRDQVVFITGGARGIGAEVARRLAAKGAKLVLTDLNEADLTALADELG-EDRVLTAV 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDL AMQAAA AVERFGGIDVVVANAGI SYGSV +VDP+AF+RVLD+N+LG FHT Sbjct 60 ADVRDLSAMQAAAARAVERFGGIDVVVANAGIMSYGSVTQVDPEAFKRVLDINVLGVFHT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRA LPAL +RRGYVLIVSSLAA+ A PG+APYN SKA E FANALRLEVA GV VGS Sbjct 120 VRAALPALTERRGYVLIVSSLAAYTACPGLAPYNASKAAVEMFANALRLEVARHGVRVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDTALVRDT+ DL AF +LLA PWPLNKTT+V+KCAAAFV GI R+ RVYCP Sbjct 180 AHMSWIDTALVRDTQTDLSAFNQLLASFPWPLNKTTTVDKCAAAFVKGIRRRRTRVYCPR 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLENS 293 WVALFRW+KP+LS+ VG+ P+ + A+L+PQ+DA+VAALGR SAY + L S Sbjct 240 WVALFRWVKPVLSSAVGEAPLHKSTAELLPQLDAQVAALGRSTSAYNQGLGKS 292 >gi|333990413|ref|YP_004523027.1| dehydrogenase [Mycobacterium sp. JDM601] gi|333486381|gb|AEF35773.1| dehydrogenase [Mycobacterium sp. JDM601] Length=291 Score = 409 bits (1050), Expect = 3e-112, Method: Compositional matrix adjust. Identities = 210/292 (72%), Positives = 244/292 (84%), Gaps = 1/292 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 M ++ +V+FITG A GIGA+ ARRLH +GAKLVLTDL +++L ELGGD R+LTV Sbjct 1 MVAIHSQVIFITGGAHGIGADTARRLHAQGAKLVLTDLDQAQLTAFADELGGD-RVLTVA 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDL AMQAAA+ AVERFG ID VVANAGIASYGS+L VDP+AFRRV+DVNL+G F+T Sbjct 60 ADVRDLDAMQAAADAAVERFGRIDTVVANAGIASYGSLLAVDPEAFRRVIDVNLVGVFNT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLPA+++RRGYVLIVSSLAAFAA PGM PY+ SKAG EH ANALRLEVAHLGV+VGS Sbjct 120 VRATLPAIVERRGYVLIVSSLAAFAAAPGMIPYDASKAGVEHLANALRLEVAHLGVTVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDTALVRDTK+DL F ELLA+LPWPLNKTTSV +C AFV+GIE R+ RVYCP Sbjct 180 AHMSWIDTALVRDTKSDLSTFGELLAKLPWPLNKTTSVAECVDAFVDGIENRRTRVYCPR 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 WV LFRWLKPLLS+ V + I A+++P+MDAEVAALGR SAY E++E Sbjct 240 WVGLFRWLKPLLSSGVAEGQIGKVAAEMLPRMDAEVAALGRSTSAYNEAIEK 291 >gi|108800118|ref|YP_640315.1| short chain dehydrogenase [Mycobacterium sp. MCS] gi|119869246|ref|YP_939198.1| short chain dehydrogenase [Mycobacterium sp. KMS] gi|108770537|gb|ABG09259.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. MCS] gi|119695335|gb|ABL92408.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. KMS] Length=294 Score = 398 bits (1022), Expect = 7e-109, Method: Compositional matrix adjust. Identities = 199/292 (69%), Positives = 235/292 (81%), Gaps = 1/292 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTS+ GKVV ITG ARG+G E+ARRLH KGAKLVLTDL L+ + A+LG + R+LTVV Sbjct 4 MTSVHGKVVLITGGARGVGEELARRLHAKGAKLVLTDLDDGPLSALAADLGAE-RVLTVV 62 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADV DL MQ+AAE AV RFGGID+V+ANAGIASYGSVL VDP AFRRVLDVN++G F+T Sbjct 63 ADVCDLETMQSAAEQAVSRFGGIDIVIANAGIASYGSVLVVDPDAFRRVLDVNVVGVFNT 122 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRA LP++I+R+GY+L+VSSLAAFAA PGMAPY+ SKAG EHFANALRLEVAH GV+VG Sbjct 123 VRAALPSVIERKGYILVVSSLAAFAAAPGMAPYDASKAGVEHFANALRLEVAHHGVTVGC 182 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDT LV+DTKADLP+F +L LP PL+KTTSV KC FV GIE R++R+YCPG Sbjct 183 AHMSWIDTPLVQDTKADLPSFRTMLDSLPGPLSKTTSVQKCGEVFVKGIERRRERIYCPG 242 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 WV L RW KP+L+TR+GQ + T K++PQMDAEV AL R A T L+ Sbjct 243 WVGLIRWAKPILTTRIGQASVLKTAPKVLPQMDAEVTALKRSLGARTHGLKK 294 >gi|126435743|ref|YP_001071434.1| short chain dehydrogenase [Mycobacterium sp. JLS] gi|126235543|gb|ABN98943.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. JLS] Length=291 Score = 397 bits (1021), Expect = 9e-109, Method: Compositional matrix adjust. Identities = 199/292 (69%), Positives = 235/292 (81%), Gaps = 1/292 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTS+ GKVV ITG ARG+G E+ARRLH KGAKLVLTDL L+ + A+LG + R+LTVV Sbjct 1 MTSVHGKVVLITGGARGVGEELARRLHAKGAKLVLTDLDDGPLSALAADLGAE-RVLTVV 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADV DL MQ+AAE AV RFGGID+V+ANAGIASYGSVL VDP AFRRVLDVN++G F+T Sbjct 60 ADVCDLETMQSAAEQAVSRFGGIDIVIANAGIASYGSVLVVDPDAFRRVLDVNVVGVFNT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRA LP++I+R+GY+L+VSSLAAFAA PGMAPY+ SKAG EHFANALRLEVAH GV+VG Sbjct 120 VRAALPSVIERKGYILVVSSLAAFAAAPGMAPYDASKAGVEHFANALRLEVAHHGVTVGC 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDT LV+DTKADLP+F +L LP PL+KTTSV KC FV GIE R++R+YCPG Sbjct 180 AHMSWIDTPLVQDTKADLPSFRTMLDSLPGPLSKTTSVQKCGEVFVKGIERRRERIYCPG 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 WV L RW KP+L+TR+GQ + T K++PQMDAEV AL R A T L+ Sbjct 240 WVGLIRWAKPILTTRIGQASVLKTAPKVLPQMDAEVTALKRSLGARTHGLKK 291 >gi|118472164|ref|YP_888467.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] gi|118173451|gb|ABK74347.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] Length=295 Score = 368 bits (944), Expect = 7e-100, Method: Compositional matrix adjust. Identities = 197/290 (68%), Positives = 234/290 (81%), Gaps = 2/290 (0%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 SL GKVVFITG G+GAEV+RRL+ KGAKL+L D+ L LG D + T VAD Sbjct 7 SLGGKVVFITGGGAGVGAEVSRRLYRKGAKLMLVDVDADALKAHADTLGED--VATAVAD 64 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 VRDL AM+AAA+ AVERFGGIDVVVANAG+ASYGSV +VDP+AF+R+LD+N+LG FHTVR Sbjct 65 VRDLAAMKAAADAAVERFGGIDVVVANAGVASYGSVQQVDPEAFKRLLDINVLGVFHTVR 124 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 ATLP++I+RRGYVLIVSSLAA+AA PG+APYN SKA E FANALRLEVAH GV VGSAH Sbjct 125 ATLPSVIERRGYVLIVSSLAAYAASPGLAPYNASKAAVEQFANALRLEVAHRGVDVGSAH 184 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 MSWIDTA+V D+KADL F E+L++LP PL+ TTSV+ C AFV GIE R R+ CPGWV Sbjct 185 MSWIDTAMVNDSKADLSTFGEMLSKLPPPLSSTTSVSACGEAFVKGIERRARRINCPGWV 244 Query 243 ALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 FRWLKP+LSTR+G+ P+ V L+P+MDAEVAALGR +SA+TES+E Sbjct 245 EAFRWLKPILSTRLGELPVLRFVPDLLPRMDAEVAALGRSSSAHTESIEK 294 >gi|145223637|ref|YP_001134315.1| short chain dehydrogenase [Mycobacterium gilvum PYR-GCK] gi|315443964|ref|YP_004076843.1| short-chain alcohol dehydrogenase [Mycobacterium sp. Spyr1] gi|145216123|gb|ABP45527.1| short-chain dehydrogenase/reductase SDR [Mycobacterium gilvum PYR-GCK] gi|315262267|gb|ADT99008.1| short-chain alcohol dehydrogenase [Mycobacterium sp. Spyr1] Length=295 Score = 363 bits (933), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 195/290 (68%), Positives = 236/290 (82%), Gaps = 1/290 (0%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 S+ GK VFITG ARG+G EVARRLH +GA+LVLTDL + LA + LG + R+ TV AD Sbjct 6 SIDGKTVFITGGARGVGEEVARRLHARGARLVLTDLDEPPLAALRDRLGAE-RVHTVTAD 64 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 VRDL AM+AAA A++RFGGIDVV+ANAGIASYGSVL+VDPQAFR ++DVN+LG FHTVR Sbjct 65 VRDLSAMEAAAAGAIDRFGGIDVVMANAGIASYGSVLQVDPQAFRTLMDVNVLGVFHTVR 124 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 ATLP++++RRGYVLIVSSLAA+AA PG+APYN +KA EHFANALRLEV + GV VGSAH Sbjct 125 ATLPSVLERRGYVLIVSSLAAYAAAPGLAPYNATKAAVEHFANALRLEVGYRGVDVGSAH 184 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 MSWIDT LVRDT+ADLP F E+++RLP+PLN+TTSV C AAFV+GIE R ++ PGWV Sbjct 185 MSWIDTPLVRDTRADLPTFTEMISRLPFPLNRTTSVEACGAAFVSGIEKRNRQINSPGWV 244 Query 243 ALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 L RWLKP+LST +G+ P+ V L+P+MDAEVAALGR T+ LE+ Sbjct 245 GLMRWLKPVLSTPIGETPVLKFVPDLLPRMDAEVAALGRSMGTRTKDLED 294 >gi|120404449|ref|YP_954278.1| short chain dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119957267|gb|ABM14272.1| short-chain dehydrogenase/reductase SDR [Mycobacterium vanbaalenii PYR-1] Length=292 Score = 362 bits (930), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 195/292 (67%), Positives = 239/292 (82%), Gaps = 1/292 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 M ++ GK VFITG ARG+GAEVARRLH KGA+LVLTDL ++ L + LG DR+ T+V Sbjct 1 MGAVAGKTVFITGGARGVGAEVARRLHAKGARLVLTDLDEAPLTELRDSLG-PDRVHTIV 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVR+L AM+AAA +AV+RFGGID+V+ANAGIA+YGSVL+VDP+AFR ++DVN++G FHT Sbjct 60 ADVRELTAMEAAAASAVDRFGGIDIVMANAGIATYGSVLQVDPEAFRTLMDVNVMGVFHT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRATLP++++RRGYVLIVSSLAA+AA PG+APYN +KA EHFANALRLEV GV+VGS Sbjct 120 VRATLPSVLERRGYVLIVSSLAAYAAAPGLAPYNAAKAAVEHFANALRLEVGFRGVAVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDT LVRDTKADLP FAE+L+RLP+PLN+TTSV C AFV GIE RK ++ CPG Sbjct 180 AHMSWIDTPLVRDTKADLPTFAEMLSRLPFPLNQTTSVEACGEAFVTGIEQRKRQINCPG 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 WV + RWLK LLST +G++ + V L+P+MDAEVAALGR T+ LE Sbjct 240 WVGVLRWLKSLLSTPIGEQQVLKFVPDLLPRMDAEVAALGRSMGTRTQRLEE 291 >gi|169629203|ref|YP_001702852.1| short chain dehydrogenase [Mycobacterium abscessus ATCC 19977] gi|169241170|emb|CAM62198.1| Hypothetical short-chain dehydrogenase/reductase [Mycobacterium abscessus] Length=293 Score = 357 bits (915), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 175/283 (62%), Positives = 218/283 (78%), Gaps = 1/283 (0%) Query 6 GKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADVRD 65 GK V ITG A GIG EVA RL+ KGA +VLTDL +++LA + ELGGD R+L VADV D Sbjct 10 GKTVMITGGAGGIGVEVAHRLYAKGANVVLTDLDEAKLAAIADELGGD-RVLVAVADVCD 68 Query 66 LPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRATL 125 L AM+ A AV+RFGGIDVVVANAG+ ++GSVL++DP F++++DVN+LG FHTVRA L Sbjct 69 LTAMEKVAAQAVQRFGGIDVVVANAGLLTFGSVLQIDPATFKKLIDVNVLGVFHTVRAAL 128 Query 126 PALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHMSW 185 P++I+RRGYVL+VSSLAA+AA P + YN SKA EHFANALRLEVAH GV VGSAHMSW Sbjct 129 PSVIERRGYVLVVSSLAAYAASPAVTAYNASKAAVEHFANALRLEVAHRGVDVGSAHMSW 188 Query 186 IDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVALF 245 IDT++V D K++L AF+E+L RLP PL TSV C AFV GIE R R+ CPGWV + Sbjct 189 IDTSMVNDQKSNLSAFSEMLTRLPPPLRTVTSVQACGRAFVKGIERRSRRINCPGWVGIT 248 Query 246 RWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTE 288 RWLKP+LSTR+G+ P+R + +++P++DAEVA L R A E Sbjct 249 RWLKPVLSTRLGEIPVRGMIPEILPRIDAEVAELQRAARDAIE 291 >gi|226362057|ref|YP_002779835.1| short chain dehydrogenase [Rhodococcus opacus B4] gi|226240542|dbj|BAH50890.1| putative oxidoreductase [Rhodococcus opacus B4] Length=297 Score = 346 bits (888), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 175/292 (60%), Positives = 217/292 (75%), Gaps = 1/292 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 M +L+ KV +TGAARGIGA +R L KG KL+L DL L + AELG D L V Sbjct 1 MPTLRNKVALVTGAARGIGAATSRALARKGVKLILIDLDAGPLKALAAELGAD-VALDVA 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADV DL A+Q A + V +FGGID+VVANAGIASYGSV++VDP F+RV+D+N+LG FHT Sbjct 60 ADVCDLAAVQKAVDAGVAKFGGIDLVVANAGIASYGSVMQVDPATFKRVIDINILGVFHT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRA LP++I+R+GY+L+VSSLAAFA PG+A YN SKAG EHFAN LRLEVAH GV+VGS Sbjct 120 VRAALPSVIERKGYILVVSSLAAFAPAPGLAAYNTSKAGIEHFANTLRLEVAHHGVAVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDT LV+D KADL AF +LLA LP PL KTTSV+ C AFV+ + GRK RVY P Sbjct 180 AHMSWIDTPLVQDAKADLTAFNQLLAVLPGPLGKTTSVDACVDAFVDALAGRKRRVYVPR 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 WV L WLK ++++ +G R + V +++P+MD EVA LGR SA +L++ Sbjct 240 WVELVSWLKAVVTSPIGDRSLLPHVPEILPRMDEEVAKLGRSTSARNVALDD 291 >gi|111019909|ref|YP_702881.1| short chain dehydrogenase [Rhodococcus jostii RHA1] gi|110819439|gb|ABG94723.1| probable carveol dehydrogenase [Rhodococcus jostii RHA1] Length=297 Score = 339 bits (869), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 171/292 (59%), Positives = 212/292 (73%), Gaps = 1/292 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 M +L+ KV +TGAARGIGAE +R L KG KLVL DL L + AELG DD + Sbjct 1 MPTLRNKVALVTGAARGIGAETSRALARKGVKLVLIDLDAEPLNALAAELG-DDVAIAAT 59 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADV DL A+Q A + + +FGGID+V+ANAGIAS+GSVL VDP F+RV+D+N+LG FHT Sbjct 60 ADVCDLAAVQKAVDAGIAKFGGIDLVLANAGIASFGSVLHVDPATFKRVIDINILGVFHT 119 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 VRA LP++I+R+GY+L+VSSLAAFA G+ YN SKAG EHFANALRLEVAH GV+VGS Sbjct 120 VRAALPSVIERKGYILVVSSLAAFAPVAGLTAYNASKAGIEHFANALRLEVAHHGVTVGS 179 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AHMSWIDT LV+D KADL AF + LA LP PL KTTSV C AFV+ + RK RVY P Sbjct 180 AHMSWIDTPLVQDAKADLTAFNQFLASLPGPLGKTTSVGSCVDAFVDALAKRKRRVYVPR 239 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 WV +F WLK ++++R+G R + V +++P MD E A LGR SA +L + Sbjct 240 WVGIFAWLKAVVTSRIGDRTLLPPVPRILPLMDEEAAKLGRCTSARNVALGD 291 >gi|134097771|ref|YP_001103432.1| short chain dehydrogenase [Saccharopolyspora erythraea NRRL 2338] gi|291005593|ref|ZP_06563566.1| short chain dehydrogenase [Saccharopolyspora erythraea NRRL 2338] gi|133910394|emb|CAM00507.1| oxidoreductase, short-chain dehydrogenase/reductase family [Saccharopolyspora erythraea NRRL 2338] Length=293 Score = 286 bits (733), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 154/292 (53%), Positives = 197/292 (68%), Gaps = 2/292 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 M + GKVV ITGAARGIGAE AR L +GA+L L L EL + AELG D Sbjct 1 MPKMSGKVVLITGAARGIGAETARHLARRGAQLSLVGLEPEELRAVAAELG--DGHTWFE 58 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADV D ++ AA E V GGIDVV+ANAGIA +G+V D +AF + +DVNL G FHT Sbjct 59 ADVTDPDSIGAAVEHTVAELGGIDVVIANAGIAPFGTVRDHDTRAFTKTIDVNLNGVFHT 118 Query 121 VRATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGS 180 +A LP +IDRRGYVL+VSSL+AFA GMA Y SKAG E A+AL EVAHLGV+VGS Sbjct 119 AKAALPHVIDRRGYVLVVSSLSAFAPVGGMAAYTASKAGAEALASALHSEVAHLGVAVGS 178 Query 181 AHMSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPG 240 AH SWIDT LVRD ADL +F + LPWP++ TTSV KCA AF +G+E R R+Y P Sbjct 179 AHPSWIDTDLVRDASADLASFRRMRELLPWPMHATTSVEKCARAFADGVERRARRIYVPR 238 Query 241 WVALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 + L W++ + ++R+ R +R ++ +++PQM+ EVA LGR SA + +++ Sbjct 239 AIMLMHWIRNVPASRLVGRLMRPSLRRIVPQMEREVAELGRSFSARNDRIQS 290 >gi|289745402|ref|ZP_06504780.1| hypothetical oxidoreductase [Mycobacterium tuberculosis 02_1987] gi|289685930|gb|EFD53418.1| hypothetical oxidoreductase [Mycobacterium tuberculosis 02_1987] Length=199 Score = 271 bits (692), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 138/138 (100%), Positives = 138/138 (100%), Gaps = 0/138 (0%) Query 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV Sbjct 1 MTSLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVV 60 Query 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT Sbjct 61 ADVRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHT 120 Query 121 VRATLPALIDRRGYVLIV 138 VRATLPALIDRRGYVLIV Sbjct 121 VRATLPALIDRRGYVLIV 138 >gi|315506284|ref|YP_004085171.1| short-chain dehydrogenase/reductase sdr [Micromonospora sp. L5] gi|315412903|gb|ADU11020.1| short-chain dehydrogenase/reductase SDR [Micromonospora sp. L5] Length=297 Score = 243 bits (621), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 143/284 (51%), Positives = 184/284 (65%), Gaps = 2/284 (0%) Query 4 LQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADV 63 L GKVV +TGAARGIG AR +GA+L L L LA + AELG ADV Sbjct 11 LAGKVVLVTGAARGIGEHTARLAAARGARLSLVGLEPDRLAALAAELGPGHAWFA--ADV 68 Query 64 RDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRA 123 D A+ AA + + GGID VVANAG+A+ G++ D +A R ++VNL+G T A Sbjct 69 TDQDALAAAVDGTLATLGGIDAVVANAGVANRGTIAVGDVEALVRTVEVNLIGVMRTAAA 128 Query 124 TLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHM 183 T+PAL+DR GY+LIVSS AAFAA PGMA Y SKAG E F NA+RLE+AH GV+VG+AH Sbjct 129 TVPALVDRGGYLLIVSSAAAFAALPGMAAYCASKAGVEQFGNAVRLELAHRGVAVGTAHP 188 Query 184 SWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVA 243 SW+DT LVR+ +ADLPAF+ LA+LPWPL +TT+V +CA AFV IE R RVY P VA Sbjct 189 SWVDTDLVREARADLPAFSTALAKLPWPLRRTTTVTECAEAFVRAIERRSRRVYVPRAVA 248 Query 244 LFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYT 287 + ++ +L + + R + T +P ++ + ALGR A T Sbjct 249 GVQAMRSVLVSPLADRLVGRTARATVPLIEEQSRALGRGFGAST 292 >gi|302867310|ref|YP_003835947.1| short-chain dehydrogenase/reductase SDR [Micromonospora aurantiaca ATCC 27029] gi|302570169|gb|ADL46371.1| short-chain dehydrogenase/reductase SDR [Micromonospora aurantiaca ATCC 27029] Length=297 Score = 243 bits (621), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 143/284 (51%), Positives = 184/284 (65%), Gaps = 2/284 (0%) Query 4 LQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADV 63 L GKVV +TGAARGIG AR +GA+L L L LA + AELG ADV Sbjct 11 LAGKVVLVTGAARGIGEHTARLAAARGARLSLVGLEPDRLAALAAELGPGHAWFA--ADV 68 Query 64 RDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRA 123 D A+ AA + + GGID VVANAG+A+ G++ D +A R ++VNL+G T A Sbjct 69 TDQNALAAAVDGTLATLGGIDAVVANAGVANRGTIAVGDVEALVRTVEVNLIGVMRTAAA 128 Query 124 TLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHM 183 T+PAL+DR GY+LIVSS AAFAA PGMA Y SKAG E F NA+RLE+AH GV+VG+AH Sbjct 129 TVPALVDRGGYLLIVSSAAAFAALPGMAAYCASKAGVEQFGNAVRLELAHRGVAVGTAHP 188 Query 184 SWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVA 243 SW+DT LVR+ +ADLPAF+ LA+LPWPL +TT+V +CA AFV IE R RVY P VA Sbjct 189 SWVDTDLVREARADLPAFSTALAKLPWPLRRTTTVTECAEAFVRAIERRSRRVYVPRAVA 248 Query 244 LFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYT 287 + ++ +L + + R + T +P ++ + ALGR A T Sbjct 249 GVQAMRSVLVSPLADRLVGRTARATVPLIEEQSRALGRGFGAST 292 >gi|333921848|ref|YP_004495429.1| oxidoreductase, short-chain dehydrogenase/reductase family [Amycolicicoccus subflavus DQS3-9A1] gi|333484069|gb|AEF42629.1| Oxidoreductase, short-chain dehydrogenase/reductase family [Amycolicicoccus subflavus DQS3-9A1] Length=287 Score = 242 bits (618), Expect = 5e-62, Method: Compositional matrix adjust. Identities = 135/285 (48%), Positives = 183/285 (65%), Gaps = 2/285 (0%) Query 6 GKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADVRD 65 GK +TGA+RGIGA VA+ L +G + LT + ELA + E+G + + VADV Sbjct 4 GKTALLTGASRGIGAAVAQELAARGWNVALTGIEPEELAWIAREIGPN--AASFVADVTS 61 Query 66 LPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRATL 125 ++AA AVERFGGID V+ANAGIAS+G+V DP+AF R +D+NL G F TVRA L Sbjct 62 QEQLEAAVADAVERFGGIDAVIANAGIASFGTVRVTDPEAFARTIDINLTGAFRTVRAAL 121 Query 126 PALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHMSW 185 PA+I+RRGYVL+++S+A+FA G+A Y SKAG E F++AL EV LGV VG AH SW Sbjct 122 PAIIERRGYVLVIASVASFAPIAGLAAYAASKAGAEAFSSALATEVDGLGVRVGCAHPSW 181 Query 186 IDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVALF 245 IDT +VRD ++DL +F ++ LPWPL+ TT++ CA +GIE R+ R+Y PG V + Sbjct 182 IDTDMVRDAESDLSSFQQMRQVLPWPLHSTTTLEACAKMIADGIENRRRRIYVPGSVRVV 241 Query 246 RWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESL 290 W++ LL + G ++ ++ EV LGR S E L Sbjct 242 YWMRALLQSGPGLALASKFARPMISLIEEEVHQLGRSVSERVERL 286 >gi|311742026|ref|ZP_07715836.1| short-chain dehydrogenase/reductase family oxidoreductase [Aeromicrobium marinum DSM 15272] gi|311314519|gb|EFQ84426.1| short-chain dehydrogenase/reductase family oxidoreductase [Aeromicrobium marinum DSM 15272] Length=295 Score = 220 bits (560), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 129/289 (45%), Positives = 171/289 (60%), Gaps = 2/289 (0%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 GKV+ +TGAARGIGA VAR +G K+ L L L + AELG D AD Sbjct 4 KFNGKVLLVTGAARGIGAGVARGYVARGGKVALLGLEPDLLGALAAELG--DAAAWWEAD 61 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 RD M AA + A FG ID V+ANAGIASYG+V ++D +F RV+D+N+ G + T+ Sbjct 62 ARDGAQMTAAIDAAAAHFGRIDHVLANAGIASYGTVRQIDEASFERVIDINVTGVYRTLH 121 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 +P L++ +G+ L+V+SLA+F+ G+A YN SKAG E A A EVAHLGV VG H Sbjct 122 PAIPHLVETKGHALVVASLASFSNLAGLAAYNASKAGAESLALATAQEVAHLGVKVGVVH 181 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 WIDT +VR +ADLP F + +LP+P N TT++ C + G RK RVY P V Sbjct 182 PGWIDTDIVRGAEADLPTFKVIRGKLPYPANSTTNLADCVDGILRGFARRKTRVYVPRGV 241 Query 243 ALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLE 291 L W KPLL++ I+ + +P ++ EV ALGRF A+ E Sbjct 242 VLANWTKPLLNSPPVLMIIKRIARRHVPDLEREVDALGRFQHAHVPLTE 290 >gi|297204820|ref|ZP_06922217.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces sviceus ATCC 29083] gi|197712535|gb|EDY56569.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces sviceus ATCC 29083] Length=298 Score = 218 bits (555), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 122/278 (44%), Positives = 173/278 (63%), Gaps = 2/278 (0%) Query 4 LQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADV 63 L + + +TGAARGIG +VAR ++GA++ + L L + +LG ADV Sbjct 5 LLDRRLIVTGAARGIGEKVARLAASRGARVTVIGLEPDRLHALADDLGPGASWKE--ADV 62 Query 64 RDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRA 123 RD A+++A + A E GG+D+VVANAG+ YG+V + D +F+RVLD+N+ G F T++ Sbjct 63 RDGAALRSAIDEAAEAMGGVDLVVANAGVVGYGTVRQTDEASFQRVLDINVNGVFRTLKY 122 Query 124 TLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHM 183 P L RG+VL+V+S +F PGMA Y SKAG E A R EVAHLG++VG H Sbjct 123 VTPHLERSRGHVLVVASALSFMPFPGMASYGASKAGTELLALTYRQEVAHLGITVGLVHP 182 Query 184 SWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVA 243 SWI+T LVR +AD+P+FA +LP+P N TTS ++ A A VNG+ R+ RVY P V Sbjct 183 SWINTDLVRGGEADIPSFAAFREKLPYPGNVTTSADRAADAIVNGLVRRRSRVYIPRAVV 242 Query 244 LFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVAALGR 281 + W K +L++ + R A+ +P ++ EVAALGR Sbjct 243 VVNWAKAVLNSPLAWPWARRFAARAVPSLEREVAALGR 280 >gi|72162101|ref|YP_289758.1| short chain dehydrogenase [Thermobifida fusca YX] gi|71915833|gb|AAZ55735.1| probable 3-oxoacyl-(acyl carrier protein) reductase [Thermobifida fusca YX] Length=301 Score = 207 bits (526), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 131/273 (48%), Positives = 166/273 (61%), Gaps = 10/273 (3%) Query 5 QGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADVR 64 G V +TGAARG+GA +ARRL GA++ L L ELA A G + V DV Sbjct 8 DGTVAVVTGAARGVGALLARRLAACGARVALVGLEPEELATTAAACGPESSFWEV--DVT 65 Query 65 DLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRAT 124 D A+ AAA +R+G ID+VVANAGIA G L DP F RV++VNLLG+ T RA Sbjct 66 DRAALAAAAREIEDRYGRIDIVVANAGIAVGGPFLDSDPVFFDRVIEVNLLGSVATARAF 125 Query 125 LPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHMS 184 LPAL+ RGY+L ++SLAA P M+ Y SK+G E FA A+R+EVAH GV VG A++S Sbjct 126 LPALLRHRGYLLQIASLAALTPAPMMSAYCASKSGVEAFAQAVRIEVAHRGVDVGVAYLS 185 Query 185 WIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV-- 242 W DT +VR AD A EL +RLPWPLN+T + + A V GI R RVY W+ Sbjct 186 WTDTDMVRGADADT-ALRELRSRLPWPLNRTYPLPRTVDALVAGIVRRAPRVYGQRWLPA 244 Query 243 -ALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDA 274 L R + P L TR+G R VA+L P+++A Sbjct 245 MQLVRGILPPLLTRLGSR----EVARLEPKLNA 273 >gi|337766161|emb|CCB74872.1| Short chain dehydrogenase [Streptomyces cattleya NRRL 8057] Length=299 Score = 203 bits (517), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 125/264 (48%), Positives = 154/264 (59%), Gaps = 8/264 (3%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 +L G+V +TGAARG+GA +AR L +GA+L L L ELA + EL D T AD Sbjct 4 TLHGQVAVVTGAARGVGALLARHLRRRGAQLALVGLEPDELAKVADEL--DAGYWT--AD 59 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D AM AE +R+G IDVVVANAGIA+ G DP AF RV++VNLLG+ T R Sbjct 60 VTDGAAMTRVAEEIADRYGRIDVVVANAGIATGGPFTDADPAAFDRVIEVNLLGSVATAR 119 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 A LPALI RGY L ++SLAA P MA Y SKAG E FA++LR EV H GV VG A+ Sbjct 120 AFLPALIRSRGYYLQIASLAALTPAPMMAAYCASKAGVEAFAHSLRAEVGHRGVKVGVAY 179 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +SW DT +VR D EL +RLPWP N+T + A +G++ R VY W+ Sbjct 180 LSWTDTDMVRGADQD-DVLRELRSRLPWPANRTYPLEPAVARIADGVQRRSAHVYAQWWL 238 Query 243 ---ALFRWLKPLLSTRVGQRPIRN 263 R P L VG R +R Sbjct 239 RGMQAVRGYLPSLIGVVGPREVRR 262 >gi|297200302|ref|ZP_06917699.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces sviceus ATCC 29083] gi|197709416|gb|EDY53450.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces sviceus ATCC 29083] Length=294 Score = 201 bits (511), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 117/268 (44%), Positives = 156/268 (59%), Gaps = 6/268 (2%) Query 4 LQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADV 63 L+G+V +TGAARG+G +AR+L +GAK+ L L L + L GD ADV Sbjct 6 LEGQVAVVTGAARGVGELLARKLSARGAKVALVGLEPDALKQLSGRLHGDSDHW--YADV 63 Query 64 RDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRA 123 D AM A+ RFG +D+VVANAG+A+ G + DP+A+RRV++VNL+G+ T RA Sbjct 64 TDHAAMARVAQEVKARFGKVDIVVANAGVATGGPFVDSDPEAWRRVIEVNLIGSAVTARA 123 Query 124 TLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHM 183 LP L++ RGY+L ++SLAA P M Y SK+G E FA++LR EV H GV VG ++ Sbjct 124 FLPVLMESRGYLLQIASLAAITPAPMMTAYCASKSGVEAFAHSLRAEVGHRGVRVGVGYL 183 Query 184 SWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVA 243 SW DT +VR D EL RLPWP NKT + V GIE R VY GW+ Sbjct 184 SWTDTDMVRGADQD-AVMRELRQRLPWPANKTYPLGPAVERIVAGIERRSSHVYGQGWLR 242 Query 244 LFRWLK---PLLSTRVGQRPIRNTVAKL 268 + ++ P L VGQR +R +L Sbjct 243 GMQGMRGYLPGLIGTVGQREMRRFGQRL 270 >gi|291439112|ref|ZP_06578502.1| short chain dehydrogenase [Streptomyces ghanaensis ATCC 14672] gi|291342007|gb|EFE68963.1| short chain dehydrogenase [Streptomyces ghanaensis ATCC 14672] Length=294 Score = 200 bits (508), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 118/269 (44%), Positives = 158/269 (59%), Gaps = 6/269 (2%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 SL+G+V ITGAARG+G +AR+L +GAK+ L L L + A L GD AD Sbjct 5 SLEGQVAVITGAARGVGELLARKLSARGAKVALVGLEPDALKQVSARLHGDSEHWH--AD 62 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D AM A ERFG +D+VVANAG+A+ G + DP+++RRV++VNL+G+ T R Sbjct 63 VTDHEAMARVAREVGERFGRVDIVVANAGVATGGPFVDSDPESWRRVIEVNLIGSAVTGR 122 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 A LP L++ RGY+L ++SLAA P M Y SK+G E +A++LR EV H GV VG + Sbjct 123 AFLPLLVESRGYLLQIASLAALTPAPMMTAYCASKSGVEAYAHSLRAEVGHRGVRVGVGY 182 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +SW DT +VR D EL RLPWP NKT + V+GIE R VY W+ Sbjct 183 LSWTDTDMVRGADQD-EVMRELRQRLPWPTNKTYPLGPAVDRLVDGIERRAAHVYGQWWL 241 Query 243 ALFRWLK---PLLSTRVGQRPIRNTVAKL 268 + ++ P L VGQR +R +L Sbjct 242 RGMQGVRGHLPGLIGTVGQREMRRFADRL 270 >gi|297193887|ref|ZP_06911285.1| short chain dehydrogenase [Streptomyces pristinaespiralis ATCC 25486] gi|197720249|gb|EDY64157.1| short chain dehydrogenase [Streptomyces pristinaespiralis ATCC 25486] Length=293 Score = 199 bits (507), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 119/274 (44%), Positives = 159/274 (59%), Gaps = 10/274 (3%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 SL+G+V +TGAARG+G +AR+L +GAK+ L L EL + L + AD Sbjct 5 SLEGQVAVVTGAARGVGELLARKLSARGAKVALVGLEPDELKKVSERLHSESDHWH--AD 62 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D AM A+ ERFG ID+VVANAG+AS G L DP A+RRV++VNL+G+ T R Sbjct 63 VTDHEAMARVAQEVKERFGKIDIVVANAGVASGGPFLHSDPVAWRRVIEVNLIGSAVTGR 122 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 A LP L++ RGY L ++SLAA P M+ Y SK+G E FA++LR EV H GV VG + Sbjct 123 AFLPVLLESRGYFLQIASLAAITPAPMMSAYCASKSGVEAFAHSLRAEVGHRGVRVGVGY 182 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +SW DT +VR D EL RLPWP N+T + V GIE R VY W+ Sbjct 183 LSWTDTDMVRGADQD-DVMRELRQRLPWPSNRTYPLGPAVDRIVAGIERRSSHVYAQWWL 241 Query 243 ALFRWLK---PLLSTRVGQRPIRNTVAKLMPQMD 273 + ++ P + VGQR +R + P++D Sbjct 242 RGMQSIRGYLPAVIGTVGQREMR----RFEPRLD 271 >gi|289771101|ref|ZP_06530479.1| short chain dehydrogenase [Streptomyces lividans TK24] gi|289701300|gb|EFD68729.1| short chain dehydrogenase [Streptomyces lividans TK24] Length=297 Score = 198 bits (503), Expect = 9e-49, Method: Compositional matrix adjust. Identities = 113/264 (43%), Positives = 157/264 (60%), Gaps = 6/264 (2%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 SL+G+V +TGAARG+G +AR+L +G K+ L L EL + A L D AD Sbjct 5 SLEGRVAVVTGAARGVGELMARKLSARGVKVALVGLEPDELKQVSARLHSDSDHWH--AD 62 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D AM A+ +RFG +D+VVANAG+A+ G + DP+++RRV++VNL+G+ T R Sbjct 63 VTDHEAMARVAKEVKDRFGKVDIVVANAGVATGGPFVDSDPESWRRVIEVNLIGSAVTAR 122 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 A LPAL++ RGY+L ++SLAA P M+ Y SK+G E +A++LR EV H GV VG + Sbjct 123 AFLPALLESRGYLLQIASLAALTPAPMMSAYCASKSGVEAYAHSLRGEVGHRGVKVGVGY 182 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +SW DT +VR D EL RLPWP N+T + V G+E R VY W+ Sbjct 183 LSWTDTDMVRGADQD-DVMRELRQRLPWPTNRTYPLGPAVDRLVEGVERRSAHVYGQWWL 241 Query 243 ALFRWLK---PLLSTRVGQRPIRN 263 + ++ P L VGQR +R Sbjct 242 RGMQGVRGYLPALVGTVGQREMRR 265 >gi|21221607|ref|NP_627386.1| short chain dehydrogenase [Streptomyces coelicolor A3(2)] gi|6138855|emb|CAB59666.1| probable 3-oxoacyl-[acyl carrier protein] reductase [Streptomyces coelicolor A3(2)] Length=297 Score = 198 bits (503), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 113/264 (43%), Positives = 157/264 (60%), Gaps = 6/264 (2%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 SL+G+V +TGAARG+G +AR+L +G K+ L L EL + A L D AD Sbjct 5 SLEGRVAVVTGAARGVGELMARKLSARGVKVALVGLEPDELKQVSARLHSDSDHWH--AD 62 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D AM A+ +RFG +D+VVANAG+A+ G + DP+++RRV++VNL+G+ T R Sbjct 63 VTDHEAMARVAKEVKDRFGKVDIVVANAGVATGGPFVDSDPESWRRVIEVNLIGSAVTAR 122 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 A LPAL++ RGY+L ++SLAA P M+ Y SK+G E +A++LR EV H GV VG + Sbjct 123 AFLPALLESRGYLLQIASLAALTPAPMMSAYCASKSGVEAYAHSLRGEVGHRGVKVGVGY 182 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +SW DT +VR D EL RLPWP N+T + V G+E R VY W+ Sbjct 183 LSWTDTDMVRGADQD-DVMRELRQRLPWPTNRTYPLGPAVDRLVEGVERRSAHVYGQWWL 241 Query 243 ALFRWLK---PLLSTRVGQRPIRN 263 + ++ P L VGQR +R Sbjct 242 RGMQGVRGYLPALVGTVGQREMRR 265 >gi|294629845|ref|ZP_06708405.1| 3-oxoacyl-[acyl carrier protein] reductase [Streptomyces sp. e14] gi|292833178|gb|EFF91527.1| 3-oxoacyl-[acyl carrier protein] reductase [Streptomyces sp. e14] Length=297 Score = 197 bits (501), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 117/269 (44%), Positives = 158/269 (59%), Gaps = 6/269 (2%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 SL+G+V +TGAARG+G +AR+L +G K+ L L L + L + AD Sbjct 5 SLEGQVAVVTGAARGVGELLARKLSARGVKVALVGLEPDALKQVSERLHTESAHWH--AD 62 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D AM A ERFG +D+VVANAG+A+ G ++ DPQA+RRV++VNL+G+ T R Sbjct 63 VTDHEAMARVATEVKERFGRVDIVVANAGVATGGPFVESDPQAWRRVIEVNLIGSAVTGR 122 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 A LPAL + RGY+L V+SLAA P M+ Y SK+G E +A++LR EV H GV VG A+ Sbjct 123 AFLPALTESRGYLLQVASLAAMTPAPMMSAYCASKSGVEAYAHSLRAEVGHQGVRVGVAY 182 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +SW DT +VR D EL RLPWP NKT + V+GIE R VY W+ Sbjct 183 LSWTDTDMVRGADQD-DVMRELRQRLPWPSNKTYPLGPAVDRIVDGIERRSSHVYGQWWL 241 Query 243 ALFRWLK---PLLSTRVGQRPIRNTVAKL 268 + ++ P + VGQR +R +L Sbjct 242 RGMQSVRGYLPAVIGTVGQREMRRFADRL 270 >gi|257057765|ref|YP_003135597.1| short-chain alcohol dehydrogenase [Saccharomonospora viridis DSM 43017] gi|256587637|gb|ACU98770.1| short-chain alcohol dehydrogenase [Saccharomonospora viridis DSM 43017] Length=305 Score = 197 bits (501), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 126/299 (43%), Positives = 166/299 (56%), Gaps = 22/299 (7%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 +++ KVV ITGAARGIGA +A RL GAK+ L + E + +G + + AD Sbjct 12 TVRNKVVLITGAARGIGAGLAERLAADGAKVALVGIEADEQRKVADRIGPAAK--SWEAD 69 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D A++ A V+ FGGID+VVANAGIA+ G V VDP AF RV +V+LLG + T R Sbjct 70 VTDWEALEKAVAGVVDHFGGIDIVVANAGIATTGFVRSVDPVAFERVFEVDLLGVWRTFR 129 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 TLP +I R+GY+L +SS AA PGMA Y +KAG E F N+LR EVAHLGV VG AH Sbjct 130 VTLPHVIARKGYLLAISSFAAVVHAPGMANYASAKAGVEAFCNSLRAEVAHLGVKVGVAH 189 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +WI T LV A P F +L + +P PL KT ++ +GI R ++ P WV Sbjct 190 PTWIKTDLVESADAH-PVFGKLRSSVPGPLGKTYPLDVALDQLHDGIRRRARTIHIPRWV 248 Query 243 ALFRWLKPLLSTRVGQRPIRNTVAKL-MPQMDA------------EVAALGRFASAYTE 288 + ++ L P V++L +P+ D E A GR A TE Sbjct 249 GAMKLIRAFLP------PFVEAVSRLRVPRADKAALEDIARRGAREAAITGRSGRAATE 301 >gi|254388841|ref|ZP_05004073.1| short chain dehydrogenase [Streptomyces clavuligerus ATCC 27064] gi|294813135|ref|ZP_06771778.1| Short chain dehydrogenase [Streptomyces clavuligerus ATCC 27064] gi|326441566|ref|ZP_08216300.1| short chain dehydrogenase [Streptomyces clavuligerus ATCC 27064] gi|197702560|gb|EDY48372.1| short chain dehydrogenase [Streptomyces clavuligerus ATCC 27064] gi|294325734|gb|EFG07377.1| Short chain dehydrogenase [Streptomyces clavuligerus ATCC 27064] Length=296 Score = 196 bits (499), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 120/268 (45%), Positives = 155/268 (58%), Gaps = 6/268 (2%) Query 4 LQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADV 63 L G+VV +TGAARG+G +AR+L +GA+L L L EL + A L GD ADV Sbjct 6 LDGQVVVVTGAARGLGELMARKLSARGARLALVGLEADELKRVAARLHGDAEWWH--ADV 63 Query 64 RDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRA 123 D M A ERFG +D VVANAG+A+ G+ DP A+RRV++VNL+G+ T RA Sbjct 64 TDHEVMTRVAAEVKERFGKVDTVVANAGVATGGAFAGSDPVAWRRVIEVNLIGSAVTARA 123 Query 124 TLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHM 183 LPAL RGY+L ++SLAA ++ P M Y SK+G E FA+ LR EV H GV VG A++ Sbjct 124 FLPALTASRGYLLQIASLAAISSMPLMTAYCASKSGVEAFAHGLRAEVGHQGVRVGVAYL 183 Query 184 SWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVA 243 SW DT +VR AEL RLPWP+ +T + V GIE R VY WV Sbjct 184 SWTDTDMVRGVDQH-AVLAELRRRLPWPIGRTYPIGPTTDRLVAGIERRAAHVYGQPWVR 242 Query 244 LFRWLK---PLLSTRVGQRPIRNTVAKL 268 + L+ P L R +R +R+ KL Sbjct 243 AMQPLRGAVPGLVARASRREMRSFAPKL 270 >gi|320010287|gb|ADW05137.1| short-chain dehydrogenase/reductase SDR [Streptomyces flavogriseus ATCC 33331] Length=294 Score = 196 bits (499), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 118/275 (43%), Positives = 158/275 (58%), Gaps = 10/275 (3%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 SL+G+VV +TGAARG+G +AR+L +GA L L L EL + L + AD Sbjct 6 SLEGQVVVVTGAARGVGELLARKLSARGATLALVGLEPDELKKVSERLHSESDHWH--AD 63 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D AM AE RFG +DVVVANAG+A+ G ++ DP+A+RRV++VNL+G T R Sbjct 64 VTDHVAMSRVAEEVKARFGKVDVVVANAGVATGGPLVDSDPEAWRRVIEVNLIGGAVTAR 123 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 A LP L++ RGY L ++SLAA P M+ Y SK+G E FA+ LR EV H GV VG + Sbjct 124 AFLPVLMESRGYFLQIASLAAITPAPMMSAYCASKSGVEAFAHCLRGEVGHRGVKVGVGY 183 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +SW DT +VR D EL RLPWP N+T + V GIE R VY W+ Sbjct 184 LSWTDTDMVRGADED-DVMRELRQRLPWPTNRTYPLGPAVDRIVAGIERRSAHVYAQWWL 242 Query 243 ALFRWLKPLLST---RVGQRPIRNTVAKLMPQMDA 274 + ++ L T VGQR ++ + P++D Sbjct 243 RGMQSIRGYLPTVIGAVGQREMK----RFGPRLDG 273 >gi|345000203|ref|YP_004803057.1| short-chain dehydrogenase/reductase SDR [Streptomyces sp. SirexAA-E] gi|344315829|gb|AEN10517.1| short-chain dehydrogenase/reductase SDR [Streptomyces sp. SirexAA-E] Length=294 Score = 195 bits (495), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 118/269 (44%), Positives = 156/269 (58%), Gaps = 6/269 (2%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 SL+G+VV +TGAARG+G +AR+L +GAKL L L EL + L D AD Sbjct 6 SLEGQVVVVTGAARGVGELLARKLSARGAKLALVGLEPDELKKVSERLHSDSDHW--FAD 63 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D AM A ERFG IDVVVANAG+A+ G ++ DP A+RRV++VNL+G T R Sbjct 64 VTDHEAMAQVAREVKERFGKIDVVVANAGVATGGPLVDSDPVAWRRVIEVNLIGGAVTAR 123 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 A LP +++ RGY L ++SLAA P M+ Y SK+G E FA++LR EV + GV VG + Sbjct 124 AFLPVVMESRGYFLQIASLAALTPAPMMSAYCASKSGVEAFAHSLRAEVGYRGVKVGVGY 183 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +SW DT +VR D EL RLPWP N+T + V GIE R VY W+ Sbjct 184 LSWTDTDMVRGADED-DVMRELRQRLPWPTNRTYPLGPAVDRIVAGIERRSAHVYGQWWL 242 Query 243 ALFRWLKPLLSTR---VGQRPIRNTVAKL 268 + ++ L T VGQR ++ +L Sbjct 243 RGMQSVRGALPTVIGIVGQREMQRFGTRL 271 >gi|300790913|ref|YP_003771204.1| short-chain dehydrogenase [Amycolatopsis mediterranei U32] gi|299800427|gb|ADJ50802.1| short-chain dehydrogenase [Amycolatopsis mediterranei U32] gi|340532607|gb|AEK47812.1| short-chain dehydrogenase [Amycolatopsis mediterranei S699] Length=303 Score = 194 bits (492), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 125/290 (44%), Positives = 165/290 (57%), Gaps = 16/290 (5%) Query 4 LQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADV 63 + GKVV ITGAARGIGA +A RL +GAK+ L L E + +G + + + ADV Sbjct 14 VDGKVVLITGAARGIGAGLAERLAARGAKVALVGLEAEEQRKVADRIGPNAK--SWEADV 71 Query 64 RDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRA 123 A++ A V FGGIDVV+ANAGIA+ G V VD AF +V++V+LLG + T R Sbjct 72 TSWAALERATAGVVAHFGGIDVVIANAGIATAGFVRSVDRAAFEKVIEVDLLGVWRTFRV 131 Query 124 TLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHM 183 TLP +I+R+GY+L +SSLAA PGMA Y +KAG E F+N+LR EVAHLGV VG AH Sbjct 132 TLPHVIERKGYLLAISSLAAITHAPGMANYAAAKAGVEAFSNSLRAEVAHLGVKVGVAHP 191 Query 184 SWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVA 243 +WI T LV A P F +L A +P + KT ++ GI R ++ P WV Sbjct 192 TWIRTDLVESADAH-PVFGKLRASMPGLIGKTYPLDVALDDLEAGILKRARTIHVPRWVG 250 Query 244 LFRWLKPLLS--TRVGQRPIRNTVAKLMPQMD----AEVAALGRFASAYT 287 + L+ L +G R +P D A++ A G F SA T Sbjct 251 GLKLLRAFLPPIIEIGSR-------SRVPSADKAALADIEARGAFESAVT 293 >gi|291453531|ref|ZP_06592921.1| short chain dehydrogenase [Streptomyces albus J1074] gi|291356480|gb|EFE83382.1| short chain dehydrogenase [Streptomyces albus J1074] Length=291 Score = 194 bits (492), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 115/269 (43%), Positives = 155/269 (58%), Gaps = 6/269 (2%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 SL+G+V +TGAARG+G +AR+L +GAK+ L L EL + L D AD Sbjct 5 SLEGQVAVVTGAARGVGELLARKLSERGAKVALVGLEPDELKAVAGRLPSDADWW--YAD 62 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D A+ A RFG ID+VVANAG+A+ G + DP A+RRV++VNL+G+ T R Sbjct 63 VTDHEALAQVAREVKTRFGKIDIVVANAGVAAGGPFEESDPVAWRRVIEVNLVGSAVTAR 122 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 A LP L + RGY+L ++SLAA P M+ Y SK+G E +AN LR EVA+ GV VG + Sbjct 123 AFLPVLKESRGYLLQIASLAAITPAPMMSAYCASKSGVEAYANCLRAEVAYHGVKVGVGY 182 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +SW DT +VR D EL RLPWP NKT + V GIE R +VY W+ Sbjct 183 LSWTDTDMVRGADQD-DVMRELRQRLPWPANKTYPLPPAVDRIVTGIERRSAKVYAQPWL 241 Query 243 ALFRWLK---PLLSTRVGQRPIRNTVAKL 268 + ++ P + VG+R I+ +L Sbjct 242 RGMQSIRGYLPGIIATVGKREIKRFAPRL 270 >gi|311899614|dbj|BAJ32022.1| putative oxidoreductase [Kitasatospora setae KM-6054] Length=296 Score = 193 bits (490), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 123/277 (45%), Positives = 157/277 (57%), Gaps = 10/277 (3%) Query 4 LQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADV 63 L +VV ITGAARG+GA +AR+L +GAK+ L L +EL + A+ G D ADV Sbjct 5 LSSQVVVITGAARGLGALMARKLAERGAKVALVGLEPAELKAVAAQCG--DHASAWEADV 62 Query 64 RDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRA 123 DL A+ A +R+G ID VVANAGIA G V D + + RV++VNLLG+ T RA Sbjct 63 TDLDALTEVAGRIKDRYGRIDAVVANAGIALGGPVQDSDHRTWSRVVEVNLLGSVATARA 122 Query 124 TLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHM 183 LPAL + RGY+L ++SLAA P M+ Y SKAG E FA+ALR EVAH GV VG ++ Sbjct 123 FLPALAESRGYLLQIASLAALTPAPLMSAYCASKAGVESFAHALRAEVAHQGVKVGVGYL 182 Query 184 SWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV- 242 SW DT +VR D + A+LPWP NKT + V G+ R VY W+ Sbjct 183 SWTDTDMVRGADQD-AVLRRMRAKLPWPANKTYPIGPAVDRLVAGLARRSAHVYAQAWLR 241 Query 243 --ALFRWLKPLLSTRVGQRPIRNTVAKLMPQMDAEVA 277 R P L VG R VA+L P++ A A Sbjct 242 GMQPVRGFLPGLIALVGSR----DVARLAPELKATAA 274 >gi|295838285|ref|ZP_06825218.1| short-chain dehydrogenase/reductase family oxidoreductase [Streptomyces sp. SPB74] gi|197699647|gb|EDY46580.1| short-chain dehydrogenase/reductase family oxidoreductase [Streptomyces sp. SPB74] Length=288 Score = 192 bits (489), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 112/254 (45%), Positives = 149/254 (59%), Gaps = 3/254 (1%) Query 4 LQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVADV 63 ++G+V +TGAARG+G +AR+L G ++ L L L + L D ADV Sbjct 1 MEGQVAVVTGAARGVGELLARKLSAHGVRVALVGLEPEALKDLSTRLYADSDHWH--ADV 58 Query 64 RDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVRA 123 D AM A ERFG +D+VVANAG+AS G + DP ++RRV++VNLLG T RA Sbjct 59 TDQAAMTRVAAEVKERFGKVDIVVANAGVASGGPFMDSDPDSWRRVIEVNLLGAAATARA 118 Query 124 TLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAHM 183 LP L + RGY+L V+SLAA P M+ Y SK+G E +A+ LR EVAHLGV VG A++ Sbjct 119 FLPLLAESRGYLLQVASLAAVTPAPMMSAYCASKSGVEAYAHCLRAEVAHLGVKVGVAYL 178 Query 184 SWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWVA 243 SW DT +VR D EL ARLPWP NKT ++ ++GIE R VY W+ Sbjct 179 SWTDTDMVRGADTD-DVMRELRARLPWPANKTYPLSPAVDRLLHGIERRSAHVYGQWWLR 237 Query 244 LFRWLKPLLSTRVG 257 + ++ L T +G Sbjct 238 HMQSVRGALPTLIG 251 >gi|302531114|ref|ZP_07283456.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces sp. AA4] gi|302440009|gb|EFL11825.1| 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase [Streptomyces sp. AA4] Length=296 Score = 191 bits (486), Expect = 9e-47, Method: Compositional matrix adjust. Identities = 114/250 (46%), Positives = 148/250 (60%), Gaps = 3/250 (1%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 + GKVV ITGAARGIGA +A RL +GAK+ L L E + +G + + AD Sbjct 5 QVDGKVVLITGAARGIGAGLAERLAARGAKVALVGLEADEQEAVAKRIGPSAK--SWEAD 62 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V ++ VE+FGGID+V+ANAGIA+ G V VD AF RV++V+LLG + T R Sbjct 63 VTSWDDLERVTAGVVEQFGGIDIVIANAGIATAGFVRSVDRAAFERVIEVDLLGVWRTFR 122 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 T+P +I+RRGY+L +SSLAA PGMA Y +KAG E F N+LR EVAHLGV VG AH Sbjct 123 VTMPHVIERRGYLLGISSLAAITHAPGMANYAAAKAGVEAFCNSLRAEVAHLGVKVGVAH 182 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +WI T LV A P F +L A +P L KT ++ GI R ++ P WV Sbjct 183 PTWIRTDLVESADAH-PVFGKLRAGMPGLLGKTYPLDVALDDLEAGILRRARTIHVPRWV 241 Query 243 ALFRWLKPLL 252 + L+ L Sbjct 242 GGLKLLRSFL 251 >gi|302560177|ref|ZP_07312519.1| 3-oxoacyl-[acyl carrier protein] reductase [Streptomyces griseoflavus Tu4000] gi|302477795|gb|EFL40888.1| 3-oxoacyl-[acyl carrier protein] reductase [Streptomyces griseoflavus Tu4000] Length=294 Score = 191 bits (485), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 118/293 (41%), Positives = 160/293 (55%), Gaps = 6/293 (2%) Query 3 SLQGKVVFITGAARGIGAEVARRLHNKGAKLVLTDLSKSELAVMGAELGGDDRLLTVVAD 62 L+GKV +TGAARG+G +AR+L +G ++ L L L + A L D AD Sbjct 5 DLEGKVAVVTGAARGVGELMARKLSARGVRVALVGLEPDALKDVCARLHSDSDHWH--AD 62 Query 63 VRDLPAMQAAAETAVERFGGIDVVVANAGIASYGSVLKVDPQAFRRVLDVNLLGNFHTVR 122 V D AM AE ERFG +D+VVANAG+A+ G DP+++RRV++VNL+G+ T R Sbjct 63 VTDHEAMARVAEEVRERFGRVDIVVANAGVATGGPFADSDPESWRRVIEVNLVGSAVTAR 122 Query 123 ATLPALIDRRGYVLIVSSLAAFAAPPGMAPYNMSKAGNEHFANALRLEVAHLGVSVGSAH 182 A LP L + RGY+L ++SLAA P M Y SK+G E +A+ALR EV H GV VG + Sbjct 123 AFLPLLTESRGYLLQIASLAALTPAPMMTAYCASKSGVEAYAHALRAEVGHRGVKVGVGY 182 Query 183 MSWIDTALVRDTKADLPAFAELLARLPWPLNKTTSVNKCAAAFVNGIEGRKDRVYCPGWV 242 +SW DT +VR D EL RLPWP NKT + V G+E R VY W+ Sbjct 183 LSWTDTDMVRGADQD-DVMRELRQRLPWPSNKTYPLGPAVDRLVAGVERRASHVYGQWWL 241 Query 243 ALFRWLK---PLLSTRVGQRPIRNTVAKLMPQMDAEVAALGRFASAYTESLEN 292 + ++ P + VGQR +R +L V A G + ++ N Sbjct 242 RGMQGVRGALPGIIGTVGQREMRRFGDRLTGLRTGLVGAGGNADEQHRNTVRN 294 Lambda K H 0.321 0.134 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 483318443120 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40