BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2130c Length=414 Score E Sequences producing significant alignments: (Bits) Value gi|15609267|ref|NP_216646.1| cysteinyl-tRNA synthetase [Mycobact... 838 0.0 gi|340627139|ref|YP_004745591.1| putative cysteinyl-tRNA synthet... 835 0.0 gi|15841621|ref|NP_336658.1| cysteinyl-tRNA synthetase [Mycobact... 757 0.0 gi|183983109|ref|YP_001851400.1| cysteinyl-tRNA synthetase, MshC... 716 0.0 gi|118617863|ref|YP_906195.1| cysteinyl-tRNA synthetase [Mycobac... 712 0.0 gi|342859845|ref|ZP_08716498.1| cysteinyl-tRNA synthetase [Mycob... 711 0.0 gi|296165216|ref|ZP_06847763.1| cysteine--tRNA ligase [Mycobacte... 703 0.0 gi|13432247|sp|Q49784.3|MSHC_MYCLE RecName: Full=L-cysteine:1D-m... 692 0.0 gi|254823397|ref|ZP_05228398.1| cysteinyl-tRNA synthetase [Mycob... 692 0.0 gi|41407974|ref|NP_960810.1| cysteinyl-tRNA synthetase [Mycobact... 689 0.0 gi|336462026|gb|EGO40875.1| cysteine--1-D-myo-inosityl 2-amino-2... 688 0.0 gi|118472573|ref|YP_888468.1| cysteinyl-tRNA synthetase [Mycobac... 686 0.0 gi|219109269|pdb|3C8Z|A Chain A, The 1.6 A Crystal Structure Of ... 686 0.0 gi|120404450|ref|YP_954279.1| cysteinyl-tRNA synthetase [Mycobac... 674 0.0 gi|240171407|ref|ZP_04750066.1| cysteinyl-tRNA synthetase [Mycob... 671 0.0 gi|108800119|ref|YP_640316.1| cysteinyl-tRNA synthetase [Mycobac... 667 0.0 gi|15827673|ref|NP_301936.1| cysteinyl-tRNA synthetase [Mycobact... 665 0.0 gi|333990412|ref|YP_004523026.1| cysteinyl-tRNA synthetase MshC ... 662 0.0 gi|315443963|ref|YP_004076842.1| cysteinyl-tRNA synthetase [Myco... 654 0.0 gi|145223636|ref|YP_001134314.1| cysteinyl-tRNA synthetase [Myco... 654 0.0 gi|254775033|ref|ZP_05216549.1| cysteinyl-tRNA synthetase [Mycob... 645 0.0 gi|118465539|ref|YP_881564.1| cysteinyl-tRNA synthetase [Mycobac... 645 0.0 gi|169629202|ref|YP_001702851.1| cysteinyl-tRNA synthetase [Myco... 625 4e-177 gi|312139693|ref|YP_004007029.1| mycothiol ligase mshc [Rhodococ... 607 1e-171 gi|226306683|ref|YP_002766643.1| cysteine--1D-myo-inosityl 2-ami... 607 1e-171 gi|229494883|ref|ZP_04388636.1| cysteine--1-D-myo-inosityl 2-ami... 606 2e-171 gi|111017896|ref|YP_700868.1| cysteinyl-tRNA synthetase [Rhodoco... 603 1e-170 gi|226360027|ref|YP_002777805.1| cysteinyl-tRNA synthetase [Rhod... 600 2e-169 gi|54024903|ref|YP_119145.1| cysteinyl-tRNA synthetase [Nocardia... 587 1e-165 gi|343927961|ref|ZP_08767427.1| cysteine--1D-myo-inosityl 2-amin... 574 1e-161 gi|296139847|ref|YP_003647090.1| cysteine/1-D-myo-inosityl 2-ami... 566 2e-159 gi|262202368|ref|YP_003273576.1| cysteine/1-D-myo-inosityl 2-ami... 555 5e-156 gi|296393640|ref|YP_003658524.1| cysteine/1-D-myo-inosityl 2-ami... 554 1e-155 gi|289447749|ref|ZP_06437493.1| cysteinyl-tRNA synthetase [Mycob... 548 9e-154 gi|333919628|ref|YP_004493209.1| L-cysteine:1D-myo-inositol 2-am... 543 2e-152 gi|257056227|ref|YP_003134059.1| cysteinyl-tRNA synthetase [Sacc... 541 7e-152 gi|256376329|ref|YP_003099989.1| cysteine/1-D-myo-inosityl 2-ami... 527 1e-147 gi|326382269|ref|ZP_08203961.1| cysteinyl-tRNA synthetase [Gordo... 526 3e-147 gi|324997324|ref|ZP_08118436.1| cysteinyl-tRNA synthetase [Pseud... 522 6e-146 gi|302527180|ref|ZP_07279522.1| cysteine-1-D-myo-inosityl 2-amin... 521 1e-145 gi|134098795|ref|YP_001104456.1| cysteinyl-tRNA synthetase [Sacc... 520 2e-145 gi|300786807|ref|YP_003767098.1| cysteinyl-tRNA synthetase [Amyc... 520 3e-145 gi|331697134|ref|YP_004333373.1| cysteine/1-D-myo-inosityl 2-ami... 511 9e-143 gi|291005851|ref|ZP_06563824.1| cysteinyl-tRNA synthetase [Sacch... 510 1e-142 gi|317506755|ref|ZP_07964536.1| cysteine-1-D-myo-inosityl 2-amin... 496 2e-138 gi|258652959|ref|YP_003202115.1| cysteine/1-D-myo-inosityl 2-ami... 490 2e-136 gi|296117896|ref|ZP_06836479.1| cysteine--1-D-myo-inosityl 2-ami... 486 2e-135 gi|255325703|ref|ZP_05366800.1| cysteine--1-D-myo-inosityl 2-ami... 486 3e-135 gi|311739444|ref|ZP_07713279.1| cysteine--tRNA ligase [Corynebac... 484 1e-134 gi|306836112|ref|ZP_07469098.1| cysteine--tRNA ligase [Corynebac... 482 5e-134 >gi|15609267|ref|NP_216646.1| cysteinyl-tRNA synthetase [Mycobacterium tuberculosis H37Rv] gi|31793310|ref|NP_855803.1| cysteinyl-tRNA synthetase [Mycobacterium bovis AF2122/97] gi|121638012|ref|YP_978236.1| cysteinyl-tRNA synthetase [Mycobacterium bovis BCG str. Pasteur 1173P2] 83 more sequence titles Length=414 Score = 838 bits (2164), Expect = 0.0, Method: Compositional matrix adjust. Identities = 414/414 (100%), Positives = 414/414 (100%), Gaps = 0/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV Sbjct 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV Sbjct 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR Sbjct 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR Sbjct 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV Sbjct 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL Sbjct 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 >gi|340627139|ref|YP_004745591.1| putative cysteinyl-tRNA synthetase CysS2 [Mycobacterium canettii CIPT 140010059] gi|340005329|emb|CCC44486.1| putative cysteinyl-tRNA synthetase CysS2 [Mycobacterium canettii CIPT 140010059] Length=414 Score = 835 bits (2158), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/414 (99%), Positives = 413/414 (99%), Gaps = 0/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV Sbjct 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV Sbjct 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR Sbjct 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR Sbjct 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWR+ATALPAGPAA DV Sbjct 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRSATALPAGPAATDV 360 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL Sbjct 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 >gi|15841621|ref|NP_336658.1| cysteinyl-tRNA synthetase [Mycobacterium tuberculosis CDC1551] gi|13881872|gb|AAK46472.1| cysteinyl-tRNA synthetase [Mycobacterium tuberculosis CDC1551] Length=375 Score = 757 bits (1955), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/375 (100%), Positives = 375/375 (100%), Gaps = 0/375 (0%) Query 40 MYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVD 99 MYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVD Sbjct 1 MYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVD 60 Query 100 WRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEY 159 WRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEY Sbjct 61 WRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEY 120 Query 160 QDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWP 219 QDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWP Sbjct 121 QDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWP 180 Query 220 SPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHY 279 SPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHY Sbjct 181 SPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHY 240 Query 280 VHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEAT 339 VHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEAT Sbjct 241 VHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEAT 300 Query 340 ARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAP 399 ARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAP Sbjct 301 ARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAP 360 Query 400 KLVATAIDALLGVDL 414 KLVATAIDALLGVDL Sbjct 361 KLVATAIDALLGVDL 375 >gi|183983109|ref|YP_001851400.1| cysteinyl-tRNA synthetase, MshC [Mycobacterium marinum M] gi|310947198|sp|B2HFY1.1|MSHC_MYCMM RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|183176435|gb|ACC41545.1| cysteinyl-tRNA synthetase, MshC [Mycobacterium marinum M] Length=411 Score = 716 bits (1849), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/414 (84%), Positives = 379/414 (92%), Gaps = 3/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW PVP++PGRGP+LRLYD+ADRQVRPVAPG+ ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSSAPVPIVPGRGPELRLYDTADRQVRPVAPGNTATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDLIHRLWLDLGHE+ YVQN+TD+DDPLFERADRDGVDWRDLA EVALF EDMAALRV Sbjct 61 AFDLIHRLWLDLGHEVRYVQNVTDVDDPLFERADRDGVDWRDLAAQEVALFREDMAALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 L P DYVGATEA+AE++EL+EK+LA GAAYV+D GE+ D+Y+R+DATLQFGYESGYDR Sbjct 121 LSPHDYVGATEAVAEIIELVEKLLASGAAYVLD---GEHPDVYYRSDATLQFGYESGYDR 177 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 DTML L E+RGGDP RPGK+D LDALLWRAARPGEPSWPSPFGPGRPGWH+ECAAIALSR Sbjct 178 DTMLGLFEQRGGDPGRPGKNDALDALLWRAARPGEPSWPSPFGPGRPGWHIECAAIALSR 237 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +GSGLD+QGGGSDLIFPHHEFTAAHAECV+GERRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 238 VGSGLDVQGGGSDLIFPHHEFTAAHAECVTGERRFARHYVHAGMIGWDGHKMSKSRGNLV 297 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LRA+ V P+AVRLGLLAGHYRADRFWSQQVLDEA RL RWR AT LPAGP A V Sbjct 298 LVSGLRAEGVNPAAVRLGLLAGHYRADRFWSQQVLDEAVGRLQRWRAATTLPAGPDAAAV 357 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VARVR+YLADDL+TPKAIAALDGW TDA++YGGHD AP+LVA+ IDALLGVDL Sbjct 358 VARVRQYLADDLNTPKAIAALDGWATDALDYGGHDEVAPRLVASTIDALLGVDL 411 >gi|118617863|ref|YP_906195.1| cysteinyl-tRNA synthetase [Mycobacterium ulcerans Agy99] gi|310947204|sp|A0PQV5.1|MSHC_MYCUA RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|118569973|gb|ABL04724.1| cysteinyl-tRNA synthetase, MshC [Mycobacterium ulcerans Agy99] Length=411 Score = 712 bits (1837), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/414 (84%), Positives = 378/414 (92%), Gaps = 3/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW PVP++PGR P+LRLYD+ADRQVRPVAPG+ ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSSAPVPIVPGREPELRLYDTADRQVRPVAPGNTATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDLIHRLWLDLGHE+ YVQN+TD+DDPLFERADRDGVDWRDLA EVALF EDMAALRV Sbjct 61 AFDLIHRLWLDLGHEVRYVQNVTDVDDPLFERADRDGVDWRDLAAQEVALFREDMAALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 L P DYVGATEA+AE++EL+EK+LA GAAYV+D GE+ D+Y+R+DATLQFGYESGYDR Sbjct 121 LSPHDYVGATEAVAEIIELVEKLLASGAAYVLD---GEHPDVYYRSDATLQFGYESGYDR 177 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 DTML L E+RGGDP RPGK+D LDALLWRAARPGEPSWPSPFGPGRPGWH+ECAAIALSR Sbjct 178 DTMLGLFEQRGGDPGRPGKNDALDALLWRAARPGEPSWPSPFGPGRPGWHIECAAIALSR 237 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +GSGLD+QGGGSDLIFPHHEFTAAHAECV+GE+RFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 238 VGSGLDVQGGGSDLIFPHHEFTAAHAECVTGEQRFARHYVHAGMIGWDGHKMSKSRGNLV 297 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LRA+ V P+AVRLGLLAGHYRADRFWSQQVLDEA RL RWR AT LPAGP A V Sbjct 298 LVSGLRAEGVNPAAVRLGLLAGHYRADRFWSQQVLDEAVGRLQRWRAATTLPAGPDAAAV 357 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VARVR+YLADDL+TPKAIAALDGW TDA++YGGHD AP+LVA+ IDALLGVDL Sbjct 358 VARVRQYLADDLNTPKAIAALDGWATDALDYGGHDEVAPRLVASTIDALLGVDL 411 >gi|342859845|ref|ZP_08716498.1| cysteinyl-tRNA synthetase [Mycobacterium colombiense CECT 3035] gi|342132977|gb|EGT86197.1| cysteinyl-tRNA synthetase [Mycobacterium colombiense CECT 3035] Length=411 Score = 711 bits (1834), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/414 (84%), Positives = 380/414 (92%), Gaps = 3/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW P VPVL GRGP+LRLYD++DRQVRPVA GS ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSSPQVPVLSGRGPELRLYDTSDRQVRPVAAGSTATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDLI+R WLDLGH++HYVQN+TD+DDPL ERA+RDG+DWR+LA+ EV+L+ EDMAALR+ Sbjct 61 AFDLIYRQWLDLGHDVHYVQNVTDVDDPLLERAERDGIDWRELAEREVSLYREDMAALRI 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP++YVGATEAIAE+VEL+EKMLA GAAYV+D GEY DIY+RADAT QFGYESGYDR Sbjct 121 LPPREYVGATEAIAEVVELVEKMLASGAAYVVD---GEYPDIYYRADATPQFGYESGYDR 177 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 DTMLRL ERGGDP+RPGK+D+LDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR Sbjct 178 DTMLRLFAERGGDPQRPGKTDQLDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 237 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IGSGLDIQGGG+DLIFPHHEFTAAHAECV GERRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 238 IGSGLDIQGGGTDLIFPHHEFTAAHAECVRGERRFARHYVHAGMIGWDGHKMSKSRGNLV 297 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LRA+ VEP+A+RLGLLAGHYR DR+WS QVLDEA ARLHRWR+A ALPAGP A DV Sbjct 298 LVSQLRARGVEPAAIRLGLLAGHYRGDRYWSDQVLDEAVARLHRWRSAAALPAGPDAADV 357 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 +ARVR+YLADDL+TPKA+AALDGW TDA+EYGGHDA AP L A AIDALLGV L Sbjct 358 IARVRQYLADDLNTPKALAALDGWATDALEYGGHDAEAPTLAANAIDALLGVAL 411 >gi|296165216|ref|ZP_06847763.1| cysteine--tRNA ligase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295899405|gb|EFG78864.1| cysteine--tRNA ligase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=411 Score = 703 bits (1814), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/414 (83%), Positives = 377/414 (92%), Gaps = 3/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW PPVPV+PGRGP+LRLYD++DRQVRPVAPGS ATMYVCGITPYD+THLGHAATY+ Sbjct 1 MQSWDSPPVPVVPGRGPELRLYDTSDRQVRPVAPGSTATMYVCGITPYDSTHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL++R WLDLGH++HYVQN+TD+DDPLFERA+RDGVDWR+L EVA F EDMAALRV Sbjct 61 TFDLVYRQWLDLGHDVHYVQNVTDVDDPLFERAERDGVDWRELGDREVARFREDMAALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP++YV AT+AI E+VEL+EKMLA G AYVID G+Y D+Y+RADAT QFGYESGYDR Sbjct 121 LPPREYVAATQAIPEVVELVEKMLASGGAYVID---GDYPDVYYRADATPQFGYESGYDR 177 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TMLRL ERGGDP R GK+DELDALLWRAARPGEPSWPSPFG GRPGWHVECAAIA SR Sbjct 178 ETMLRLFGERGGDPERAGKTDELDALLWRAARPGEPSWPSPFGDGRPGWHVECAAIASSR 237 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IGSGLDIQGGGSDLIFPHHEFTAAHAECV GERRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 238 IGSGLDIQGGGSDLIFPHHEFTAAHAECVRGERRFARHYVHAGMIGWDGHKMSKSRGNLV 297 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LRAQ VEP+A+RLGLL+GHYRADRFWS QVL+EA RL RWR+AT LPAGP A DV Sbjct 298 LVSTLRAQGVEPAAIRLGLLSGHYRADRFWSPQVLEEANTRLGRWRSATGLPAGPDAADV 357 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 +ARVR+YLADDL+TPKA+AALDGW TDA+EYGGHD AP+LVATAIDALLGV+L Sbjct 358 IARVRQYLADDLNTPKALAALDGWATDALEYGGHDTDAPRLVATAIDALLGVEL 411 >gi|13432247|sp|Q49784.3|MSHC_MYCLE RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase Length=412 Score = 692 bits (1787), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/405 (85%), Positives = 366/405 (91%), Gaps = 7/405 (1%) Query 14 GRGPQLRLYDSADRQVRPV----APGSKATMYVCGITPYDATHLGHAATYVTFDLIHRLW 69 GRGP+LRLYD++DRQVRPV AP KATMYVCGITPYDATHLGHAATY+ FDLIHRLW Sbjct 11 GRGPELRLYDTSDRQVRPVSAAVAPTCKATMYVCGITPYDATHLGHAATYLAFDLIHRLW 70 Query 70 LDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRVLPPQDYVGA 129 LDLGHE+HYVQN+TD+DDPLFERADR+GVDWRDLA+ EVALF +DMA+LR+LPP DYV A Sbjct 71 LDLGHEVHYVQNVTDVDDPLFERADRNGVDWRDLAEREVALFRDDMASLRILPPHDYVAA 130 Query 130 TEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEE 189 TE I E+VEL++KML GAAYVID EY DIYFRADATLQFGYESGYDRDTMLRL E+ Sbjct 131 TETIVEIVELVDKMLVSGAAYVID---DEYPDIYFRADATLQFGYESGYDRDTMLRLYEQ 187 Query 190 RGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQG 249 GGDPRRPGK+ ELDALLWRAARPGEPSW SPFGPGRPGWHVECAAIALSRIG GLDIQG Sbjct 188 SGGDPRRPGKNGELDALLWRAARPGEPSWSSPFGPGRPGWHVECAAIALSRIGIGLDIQG 247 Query 250 GGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQD 309 GGSDLIFPHHEFTAAHAECV GERRFARHYVHAGMIGWD HKMSKSRGNLVLVS LRAQ Sbjct 248 GGSDLIFPHHEFTAAHAECVRGERRFARHYVHAGMIGWDEHKMSKSRGNLVLVSTLRAQG 307 Query 310 VEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLA 369 PSA+RLGLLAGHYRADRFWS Q+LD+A ARLHRWRTA ++PAGP DV+ARVR YLA Sbjct 308 APPSAIRLGLLAGHYRADRFWSSQLLDDAIARLHRWRTAASMPAGPDVADVIARVRGYLA 367 Query 370 DDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 DDLDTPKAIAALDGWVTDA+EYGGHDA APKL+ATAIDALLGVDL Sbjct 368 DDLDTPKAIAALDGWVTDALEYGGHDAAAPKLLATAIDALLGVDL 412 >gi|254823397|ref|ZP_05228398.1| cysteinyl-tRNA synthetase [Mycobacterium intracellulare ATCC 13950] Length=400 Score = 692 bits (1787), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/403 (84%), Positives = 371/403 (93%), Gaps = 3/403 (0%) Query 12 LPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYVTFDLIHRLWLD 71 + GRGP+LRLYD++DRQVRPVA GS ATMYVCGITPYDATHLGHAATY+ FDLI+R WLD Sbjct 1 MAGRGPELRLYDTSDRQVRPVASGSTATMYVCGITPYDATHLGHAATYLAFDLIYRQWLD 60 Query 72 LGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRVLPPQDYVGATE 131 LGH++HYVQN+TD+DDPL ERA+RDG+DWR+LAQ EV+LF EDM ALR+L P++YVGATE Sbjct 61 LGHDVHYVQNVTDVDDPLLERAERDGIDWRELAQREVSLFREDMTALRMLAPREYVGATE 120 Query 132 AIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEERG 191 AIAE+VEL+EKMLA GAAYV++ GEY DIY+RADAT QFGYESGYDR+TMLRL ERG Sbjct 121 AIAEVVELVEKMLASGAAYVVE---GEYPDIYYRADATPQFGYESGYDRETMLRLFSERG 177 Query 192 GDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGG 251 GDP+RPGK+D+LDALLWRAARPGEPSWPSPFG GRPGWHVECAAIALSRIGSGLDIQGGG Sbjct 178 GDPQRPGKTDQLDALLWRAARPGEPSWPSPFGDGRPGWHVECAAIALSRIGSGLDIQGGG 237 Query 252 SDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVE 311 SDLIFPHHEFTAAHAECV GERRFARHYVHAGMIGWDGHKMSKSRGNLVLVS LRAQ VE Sbjct 238 SDLIFPHHEFTAAHAECVRGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSTLRAQGVE 297 Query 312 PSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLADD 371 +A+RLGLLAGHYR DR+WSQQVLDEA ARL RWRTATALP GP A DV+ARVR+YLADD Sbjct 298 AAAIRLGLLAGHYRGDRYWSQQVLDEAVARLQRWRTATALPTGPDAADVIARVRQYLADD 357 Query 372 LDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 LDTPKA+AALDGW TDA+EYGGHDA AP+LVATA+DALLGV L Sbjct 358 LDTPKALAALDGWSTDALEYGGHDAEAPRLVATAVDALLGVAL 400 >gi|41407974|ref|NP_960810.1| cysteinyl-tRNA synthetase [Mycobacterium avium subsp. paratuberculosis K-10] gi|61216571|sp|Q73YS9.1|MSHC_MYCPA RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|41396328|gb|AAS04193.1| CysS2 [Mycobacterium avium subsp. paratuberculosis K-10] Length=415 Score = 689 bits (1779), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/418 (82%), Positives = 377/418 (91%), Gaps = 7/418 (1%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKA----TMYVCGITPYDATHLGHA 56 M+SW P VP LPGRGP+LRLYD++DRQVRPVA G+ TMYVCGITPYDATHLGHA Sbjct 1 MRSWSSPQVPQLPGRGPELRLYDTSDRQVRPVAAGAGPGSAATMYVCGITPYDATHLGHA 60 Query 57 ATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMA 116 ATY+ FDLI+R WLDLGH++HYVQN+TD+DDPL ERA RDGVDWR LA+ EV+LF EDMA Sbjct 61 ATYLAFDLIYRQWLDLGHDVHYVQNVTDVDDPLLERAARDGVDWRALAEREVSLFREDMA 120 Query 117 ALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYES 176 ALR+L P+DYVGATEAIA++VEL+EKMLA GAAYV+D GE+ DIY+RADATLQFGYES Sbjct 121 ALRILAPRDYVGATEAIADVVELVEKMLASGAAYVVD---GEFPDIYYRADATLQFGYES 177 Query 177 GYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAI 236 GYDR+TMLRL ERGGDP+RPGK+D LDALLWRAARPGEPSWPSPFG GRPGWHVECAAI Sbjct 178 GYDRETMLRLFAERGGDPQRPGKTDALDALLWRAARPGEPSWPSPFGNGRPGWHVECAAI 237 Query 237 ALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSR 296 ALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECV GERRFARHYVHAGMIGWDGHKMSKSR Sbjct 238 ALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVRGERRFARHYVHAGMIGWDGHKMSKSR 297 Query 297 GNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPA 356 GNLVLVS LR + VEP+A+RLGLLAGHYR DR+WS QVLDEATARL RWRTATALPAGP Sbjct 298 GNLVLVSQLRGRGVEPAAIRLGLLAGHYRGDRYWSDQVLDEATARLRRWRTATALPAGPD 357 Query 357 AVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 A DV+ARVR+YLADDL+TPKA+AALDGW TDA++YGGHD AP+LVA+A+DALLGV L Sbjct 358 ATDVIARVRQYLADDLNTPKALAALDGWTTDALDYGGHDTAAPRLVASAVDALLGVAL 415 >gi|336462026|gb|EGO40875.1| cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Mycobacterium avium subsp. paratuberculosis S397] Length=415 Score = 688 bits (1776), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/418 (82%), Positives = 377/418 (91%), Gaps = 7/418 (1%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKA----TMYVCGITPYDATHLGHA 56 M+SW P VP LPGRGP+LRLYD++DRQVRPVA G+ TMYVCGITPYDATHLGHA Sbjct 1 MRSWSSPQVPQLPGRGPELRLYDTSDRQVRPVAAGAGPGSAATMYVCGITPYDATHLGHA 60 Query 57 ATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMA 116 ATY+ FDLI+R WLDLGH++HYVQN+TD+DDPL ERA RDGVDWR LA+ EV+LF EDMA Sbjct 61 ATYLAFDLIYRQWLDLGHDVHYVQNVTDVDDPLLERAARDGVDWRALAEREVSLFREDMA 120 Query 117 ALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYES 176 ALR+L P+DYVGATEAIA++VEL+EKMLA GAAYV+D GE+ DIY+RADATLQFGYES Sbjct 121 ALRILAPRDYVGATEAIADVVELVEKMLASGAAYVVD---GEFPDIYYRADATLQFGYES 177 Query 177 GYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAI 236 GYDR+TMLRL ERGGDP+RPGK+D LDALLW+AARPGEPSWPSPFG GRPGWHVECAAI Sbjct 178 GYDRETMLRLFAERGGDPQRPGKTDALDALLWQAARPGEPSWPSPFGNGRPGWHVECAAI 237 Query 237 ALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSR 296 ALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECV GERRFARHYVHAGMIGWDGHKMSKSR Sbjct 238 ALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVRGERRFARHYVHAGMIGWDGHKMSKSR 297 Query 297 GNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPA 356 GNLVLVS LR + VEP+A+RLGLLAGHYR DR+WS QVLDEATARL RWRTATALPAGP Sbjct 298 GNLVLVSQLRGRGVEPAAIRLGLLAGHYRGDRYWSDQVLDEATARLRRWRTATALPAGPD 357 Query 357 AVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 A DV+ARVR+YLADDL+TPKA+AALDGW TDA++YGGHD AP+LVA+A+DALLGV L Sbjct 358 ATDVIARVRQYLADDLNTPKALAALDGWTTDALDYGGHDTAAPRLVASAVDALLGVAL 415 >gi|118472573|ref|YP_888468.1| cysteinyl-tRNA synthetase [Mycobacterium smegmatis str. MC2 155] gi|308197104|sp|A0QZY0.1|MSHC_MYCS2 RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|118173860|gb|ABK74756.1| cysteinyl-tRNA synthetase [Mycobacterium smegmatis str. MC2 155] Length=412 Score = 686 bits (1770), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/414 (79%), Positives = 364/414 (88%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW P +PV+PGRGP LRL+DSADRQVRPV PG ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSAPAIPVVPGRGPALRLFDSADRQVRPVTPGPTATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL+HRLWLD GH + YVQN+TD+DDPLFERA+RDG+DWR L E LF EDMAALRV Sbjct 61 TFDLVHRLWLDAGHTVQYVQNVTDVDDPLFERAERDGIDWRTLGDRETQLFREDMAALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP DYV AT+AIAE+VE++EK+LA GAAY++ E EY D+YFRADAT QFGYESGYDR Sbjct 121 LPPHDYVAATDAIAEVVEMVEKLLASGAAYIV--EDAEYPDVYFRADATAQFGYESGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 DTML L ERGGDP RPGKSD+LDALLWRA RPGEPSWPSPFG GRPGWHVEC+AIAL+R Sbjct 179 DTMLTLFAERGGDPDRPGKSDQLDALLWRAERPGEPSWPSPFGRGRPGWHVECSAIALTR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IG+GLDIQGGGSDLIFPHHE++AAHAE V+GERRFARHYVH GMIGWDGHKMSKSRGNLV Sbjct 239 IGTGLDIQGGGSDLIFPHHEYSAAHAESVTGERRFARHYVHTGMIGWDGHKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LRAQ V+PSA+RLGL +GHYR DRFWS +VLDEA ARL RWR+ATALP P A DV Sbjct 299 LVSQLRAQGVDPSAIRLGLFSGHYREDRFWSNEVLDEANARLARWRSATALPEAPDATDV 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 +ARVR+YLADDLDTPKA+AALDGW TDA+ YGGHD +P+LVAT +DALLGVDL Sbjct 359 IARVRQYLADDLDTPKALAALDGWCTDALSYGGHDTESPRLVATTVDALLGVDL 412 >gi|219109269|pdb|3C8Z|A Chain A, The 1.6 A Crystal Structure Of Mshc: The Rate Limiting Enzyme In The Mycothiol Biosynthetic Pathway gi|219109270|pdb|3C8Z|B Chain B, The 1.6 A Crystal Structure Of Mshc: The Rate Limiting Enzyme In The Mycothiol Biosynthetic Pathway Length=414 Score = 686 bits (1769), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/414 (79%), Positives = 364/414 (88%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW P +PV+PGRGP LRL+DSADRQVRPV PG ATMYVCGITPYDATHLGHAATY+ Sbjct 3 MQSWSAPAIPVVPGRGPALRLFDSADRQVRPVTPGPTATMYVCGITPYDATHLGHAATYL 62 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL+HRLWLD GH + YVQN+TD+DDPLFERA+RDG+DWR L E LF EDMAALRV Sbjct 63 TFDLVHRLWLDAGHTVQYVQNVTDVDDPLFERAERDGIDWRTLGDRETQLFREDMAALRV 122 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP DYV AT+AIAE+VE++EK+LA GAAY++ E EY D+YFRADAT QFGYESGYDR Sbjct 123 LPPHDYVAATDAIAEVVEMVEKLLASGAAYIV--EDAEYPDVYFRADATAQFGYESGYDR 180 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 DTML L ERGGDP RPGKSD+LDALLWRA RPGEPSWPSPFG GRPGWHVEC+AIAL+R Sbjct 181 DTMLTLFAERGGDPDRPGKSDQLDALLWRAERPGEPSWPSPFGRGRPGWHVECSAIALTR 240 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IG+GLDIQGGGSDLIFPHHE++AAHAE V+GERRFARHYVH GMIGWDGHKMSKSRGNLV Sbjct 241 IGTGLDIQGGGSDLIFPHHEYSAAHAESVTGERRFARHYVHTGMIGWDGHKMSKSRGNLV 300 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LRAQ V+PSA+RLGL +GHYR DRFWS +VLDEA ARL RWR+ATALP P A DV Sbjct 301 LVSQLRAQGVDPSAIRLGLFSGHYREDRFWSNEVLDEANARLARWRSATALPEAPDATDV 360 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 +ARVR+YLADDLDTPKA+AALDGW TDA+ YGGHD +P+LVAT +DALLGVDL Sbjct 361 IARVRQYLADDLDTPKALAALDGWCTDALSYGGHDTESPRLVATTVDALLGVDL 414 >gi|120404450|ref|YP_954279.1| cysteinyl-tRNA synthetase [Mycobacterium vanbaalenii PYR-1] gi|310947205|sp|A1TAS3.1|MSHC_MYCVP RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|119957268|gb|ABM14273.1| cysteinyl-tRNA synthetase [Mycobacterium vanbaalenii PYR-1] Length=429 Score = 674 bits (1739), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/414 (82%), Positives = 363/414 (88%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 M SW P VP LPGRGPQLRLYDSADRQVRPVAPG+ ATMYVCGITPYDATHLGHAATY+ Sbjct 18 MHSWSAPNVPALPGRGPQLRLYDSADRQVRPVAPGATATMYVCGITPYDATHLGHAATYL 77 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL+HRLW D GH++HYVQNITD+DDPLFERA RDG+ WR+L E LF EDMAALRV Sbjct 78 TFDLVHRLWRDSGHDVHYVQNITDVDDPLFERAQRDGIGWRELGDRETELFREDMAALRV 137 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP+DYV ATEAIAE+VEL+EKMLA GAAYV+D +Y D+YFRADAT+QFGYESGYDR Sbjct 138 LPPRDYVAATEAIAEVVELVEKMLAAGAAYVVDDP--QYPDVYFRADATVQFGYESGYDR 195 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 DTML L ERGGDP RPGKSD LDALLW A RPGEPSWPSPFGPGRPGWHVECAAIALSR Sbjct 196 DTMLALFAERGGDPDRPGKSDPLDALLWLAERPGEPSWPSPFGPGRPGWHVECAAIALSR 255 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IG+GLDIQGGGSDLIFPHHEF+AAHAECV+GERRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 256 IGTGLDIQGGGSDLIFPHHEFSAAHAECVTGERRFARHYVHAGMIGWDGHKMSKSRGNLV 315 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LR V+P+A+RLGL AGHYR DRFWS VLDEA ARLHRWR+ATAL P A DV Sbjct 316 LVSQLRRDGVDPAAIRLGLFAGHYRDDRFWSPAVLDEALARLHRWRSATALAGAPDATDV 375 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VARVRRYLADDLDTPKA+AALDGW TDA+ YGGHDA A VATA+DALLG+ L Sbjct 376 VARVRRYLADDLDTPKALAALDGWATDALTYGGHDATAGTTVATAVDALLGIAL 429 >gi|240171407|ref|ZP_04750066.1| cysteinyl-tRNA synthetase [Mycobacterium kansasii ATCC 12478] Length=383 Score = 671 bits (1730), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/383 (86%), Positives = 347/383 (91%), Gaps = 0/383 (0%) Query 32 VAPGSKATMYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFE 91 + PG KATMYVCGITPYDATHLGHAATY+ FDLIHRLWLDLGH++ YVQN+TD+DDPLFE Sbjct 1 MTPGPKATMYVCGITPYDATHLGHAATYLAFDLIHRLWLDLGHDVQYVQNVTDVDDPLFE 60 Query 92 RADRDGVDWRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYV 151 RADRDGVDWR+LA EV LF DM ALRVLPP DYV ATEA+AEMVELIEKMLA GAAY Sbjct 61 RADRDGVDWRELADREVKLFRADMEALRVLPPHDYVAATEAVAEMVELIEKMLASGAAYT 120 Query 152 IDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAA 211 +D E+G+Y DIY+RADAT+QFGYESG DRDTML L E+RGGDP RPGK+D+LDALLWRAA Sbjct 121 VDPEIGDYPDIYYRADATVQFGYESGCDRDTMLTLFEQRGGDPSRPGKTDQLDALLWRAA 180 Query 212 RPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSG 271 R GEPSWPSPFGPGRPGWHVECAAIALSRI SGLDIQGGGSDLIFPHHEFTAAHAECV+G Sbjct 181 RAGEPSWPSPFGPGRPGWHVECAAIALSRINSGLDIQGGGSDLIFPHHEFTAAHAECVTG 240 Query 272 ERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWS 331 ERRFARHYVHAGMIGWDGHKMSKSRGNLVLVS LRAQ VEPSAVRLGLLAGHYR DRFW+ Sbjct 241 ERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSTLRAQGVEPSAVRLGLLAGHYREDRFWT 300 Query 332 QQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEY 391 QVLDEA RL RWRTATALPAGP A DV+ARVRRYLADDLDTPKAIAALDGW TDA+EY Sbjct 301 HQVLDEAAGRLQRWRTATALPAGPDAADVIARVRRYLADDLDTPKAIAALDGWATDALEY 360 Query 392 GGHDAGAPKLVATAIDALLGVDL 414 GGHD AP VATAIDALLGVDL Sbjct 361 GGHDESAPTSVATAIDALLGVDL 383 >gi|108800119|ref|YP_640316.1| cysteinyl-tRNA synthetase [Mycobacterium sp. MCS] gi|119869247|ref|YP_939199.1| cysteinyl-tRNA synthetase [Mycobacterium sp. KMS] gi|126435744|ref|YP_001071435.1| cysteinyl-tRNA synthetase [Mycobacterium sp. JLS] 6 more sequence titles Length=415 Score = 667 bits (1722), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/414 (79%), Positives = 358/414 (87%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 M+SW P VP LPGRGPQLRLYDSADRQVRPV+ G ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MESWSAPEVPALPGRGPQLRLYDSADRQVRPVSAGDTATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL+HRLWLD GH +HYVQNITD+DDPLFERA RDG+DWRDL E+ LF EDMAALRV Sbjct 61 AFDLVHRLWLDAGHRVHYVQNITDVDDPLFERAARDGIDWRDLGAREIQLFREDMAALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP DYV AT+AIAE++EL+EKMLA GAAYV+D E+ D+Y+RADAT+QFGYES YD Sbjct 121 LPPHDYVAATDAIAEVIELVEKMLASGAAYVVDDP--EFPDVYYRADATVQFGYESNYDH 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TML L ERGGDP R GK+DELDALLWRA RPGEPSWPSPFGPGRPGWHVECAAIALSR Sbjct 179 ETMLTLFAERGGDPDRAGKADELDALLWRAERPGEPSWPSPFGPGRPGWHVECAAIALSR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IG+GLDIQGGGSDLIFPHHEF+AAHAE V+GERRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 239 IGTGLDIQGGGSDLIFPHHEFSAAHAESVTGERRFARHYVHAGMIGWDGHKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LRA+ V+PSA+RLGLLAGHYR DRFWS VL +A RL RWR AT+LP GP A DV Sbjct 299 LVSRLRAEGVDPSAIRLGLLAGHYREDRFWSDDVLSDAQTRLQRWRRATSLPTGPDATDV 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 +ARVR YLADDLDTPKA+ ALD W T+A++ GG D APK VATA+DALLGV L Sbjct 359 LARVRTYLADDLDTPKALIALDAWCTEALDGGGSDVTAPKTVATAVDALLGVAL 412 >gi|15827673|ref|NP_301936.1| cysteinyl-tRNA synthetase [Mycobacterium leprae TN] gi|221230150|ref|YP_002503566.1| cysteinyl-tRNA synthetase [Mycobacterium leprae Br4923] gi|310947197|sp|B8ZRD9.1|MSHC_MYCLB RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|13093224|emb|CAC31683.1| cysteinyl-tRNA synthase [Mycobacterium leprae] gi|219933257|emb|CAR71397.1| cysteinyl-tRNA synthase [Mycobacterium leprae Br4923] Length=384 Score = 665 bits (1715), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/383 (86%), Positives = 348/383 (91%), Gaps = 3/383 (0%) Query 32 VAPGSKATMYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFE 91 VAP KATMYVCGITPYDATHLGHAATY+ FDLIHRLWLDLGHE+HYVQN+TD+DDPLFE Sbjct 5 VAPTCKATMYVCGITPYDATHLGHAATYLAFDLIHRLWLDLGHEVHYVQNVTDVDDPLFE 64 Query 92 RADRDGVDWRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYV 151 RADR+GVDWRDLA+ EVALF +DMA+LR+LPP DYV ATE I E+VEL++KML GAAYV Sbjct 65 RADRNGVDWRDLAEREVALFRDDMASLRILPPHDYVAATETIVEIVELVDKMLVSGAAYV 124 Query 152 IDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAA 211 ID EY DIYFRADATLQFGYESGYDRDTMLRL E+ GGDPRRPGK+ ELDALLWRAA Sbjct 125 ID---DEYPDIYFRADATLQFGYESGYDRDTMLRLYEQSGGDPRRPGKNGELDALLWRAA 181 Query 212 RPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSG 271 RPGEPSW SPFGPGRPGWHVECAAIALSRIG GLDIQGGGSDLIFPHHEFTAAHAECV G Sbjct 182 RPGEPSWSSPFGPGRPGWHVECAAIALSRIGIGLDIQGGGSDLIFPHHEFTAAHAECVRG 241 Query 272 ERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWS 331 ERRFARHYVHAGMIGWD HKMSKSRGNLVLVS LRAQ PSA+RLGLLAGHYRADRFWS Sbjct 242 ERRFARHYVHAGMIGWDEHKMSKSRGNLVLVSTLRAQGAPPSAIRLGLLAGHYRADRFWS 301 Query 332 QQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEY 391 Q+LD+A ARLHRWRTA ++PAGP DV+ARVR YLADDLDTPKAIAALDGWVTDA+EY Sbjct 302 SQLLDDAIARLHRWRTAASMPAGPDVADVIARVRGYLADDLDTPKAIAALDGWVTDALEY 361 Query 392 GGHDAGAPKLVATAIDALLGVDL 414 GGHDA APKL+ATAIDALLGVDL Sbjct 362 GGHDAAAPKLLATAIDALLGVDL 384 >gi|333990412|ref|YP_004523026.1| cysteinyl-tRNA synthetase MshC [Mycobacterium sp. JDM601] gi|333486380|gb|AEF35772.1| cysteinyl-tRNA synthetase MshC [Mycobacterium sp. JDM601] Length=411 Score = 662 bits (1707), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/414 (79%), Positives = 355/414 (86%), Gaps = 3/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW P VP LPG GP LRLYD+ADRQVRPV+PG ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSAPAVPALPGHGPALRLYDTADRQVRPVSPGPTATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDLIHRLWLD GH + YVQN+TD+DDPL ERADRDGVDW+ LA +V LF DM ALRV Sbjct 61 VFDLIHRLWLDAGHRVDYVQNVTDVDDPLLERADRDGVDWQRLAAGQVELFAADMTALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPPQ YV A+EAI E+VE++EKMLA G+AYV+D GE+ DIYFRADAT QFGYESG DR Sbjct 121 LPPQHYVAASEAIDEVVEVVEKMLASGSAYVVD---GEHPDIYFRADATDQFGYESGLDR 177 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TML L ERGGDP R GK+D LDALLWRAARP EPSWP+PFG GRPGWHVECAAIALSR Sbjct 178 ATMLELFGERGGDPDRAGKTDPLDALLWRAARPDEPSWPAPFGAGRPGWHVECAAIALSR 237 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IGSG+DIQGGGSDLIFPHHEF+AAHAE ++GERRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 238 IGSGIDIQGGGSDLIFPHHEFSAAHAESLTGERRFARHYVHAGMIGWDGHKMSKSRGNLV 297 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LRAQ VEP+A+RLGLLAGHYR+DRFW +L EA ARL RWR AT LPAGPAA DV Sbjct 298 LVSKLRAQGVEPAAIRLGLLAGHYRSDRFWDDAILQEAQARLARWRAATTLPAGPAADDV 357 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 +AR+RRYLADDLDT KA+AALD W TDA+EYGGHD P LVATA+DALLGV L Sbjct 358 IARLRRYLADDLDTVKALAALDAWATDALEYGGHDTATPGLVATAVDALLGVAL 411 >gi|315443963|ref|YP_004076842.1| cysteinyl-tRNA synthetase [Mycobacterium sp. Spyr1] gi|315262266|gb|ADT99007.1| cysteinyl-tRNA synthetase [Mycobacterium sp. Spyr1] Length=412 Score = 654 bits (1687), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/414 (77%), Positives = 355/414 (86%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW P VP LPGRGPQLRL+DSADRQ+RPV+PG+ ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSAPSVPALPGRGPQLRLFDSADRQIRPVSPGATATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL++R+W D GH++HYVQNITD+DDPLFERA RDG+ WR+L E LF EDMAALRV Sbjct 61 TFDLVNRVWRDSGHDVHYVQNITDVDDPLFERAARDGIGWRELGDRETDLFREDMAALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 +PP+DYV ATEAIAE++E++EK+LA GAAYV+D +Y D+YF A AT+QFGYESGYDR Sbjct 121 VPPRDYVAATEAIAEVIEVVEKLLASGAAYVVDD--AQYPDVYFHAGATVQFGYESGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TML L ERGGDP RPGKSD LDALLWRA RP EPSWPSPFGPGRPGWHVECAAIA++R Sbjct 179 ETMLALFAERGGDPDRPGKSDPLDALLWRAERPEEPSWPSPFGPGRPGWHVECAAIAMTR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IG+ LDIQGGGSDLIFPHHEF++AHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 239 IGNVLDIQGGGSDLIFPHHEFSSAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LR V+P A+RLGL AGHYR DR+WS VLDEA RLHRWR+ATAL P A DV Sbjct 299 LVSQLRRDGVDPGAIRLGLFAGHYRQDRYWSPAVLDEAQQRLHRWRSATALDGAPDATDV 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VARVRRYLADDLDTPKA+AA+DGW D + YGGHD A V+ A+DALLGV L Sbjct 359 VARVRRYLADDLDTPKALAAIDGWAEDTLSYGGHDRTAGPTVSAAVDALLGVAL 412 >gi|145223636|ref|YP_001134314.1| cysteinyl-tRNA synthetase [Mycobacterium gilvum PYR-GCK] gi|310947196|sp|A4TB85.1|MSHC_MYCGI RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|145216122|gb|ABP45526.1| cysteinyl-tRNA synthetase [Mycobacterium gilvum PYR-GCK] Length=444 Score = 654 bits (1686), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/414 (77%), Positives = 355/414 (86%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW P VP LPGRGPQLRL+DSADRQ+RPV+PG+ ATMYVCGITPYDATHLGHAATY+ Sbjct 33 MQSWSAPSVPALPGRGPQLRLFDSADRQIRPVSPGATATMYVCGITPYDATHLGHAATYL 92 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL++R+W D GH++HYVQNITD+DDPLFERA RDG+ WR+L E LF EDMAALRV Sbjct 93 TFDLVNRVWRDSGHDVHYVQNITDVDDPLFERAARDGIGWRELGDRETDLFREDMAALRV 152 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 +PP+DYV ATEAIAE++E++EK+LA GAAYV+D +Y D+YF A AT+QFGYESGYDR Sbjct 153 VPPRDYVAATEAIAEVIEVVEKLLASGAAYVVDD--AQYPDVYFHAGATVQFGYESGYDR 210 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TML L ERGGDP RPGKSD LDALLWRA RP EPSWPSPFGPGRPGWHVECAAIA++R Sbjct 211 ETMLALFAERGGDPDRPGKSDPLDALLWRAERPEEPSWPSPFGPGRPGWHVECAAIAMTR 270 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IG+ LDIQGGGSDLIFPHHEF++AHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 271 IGNVLDIQGGGSDLIFPHHEFSSAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 330 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LR V+P A+RLGL AGHYR DR+WS VLDEA RLHRWR+ATAL P A DV Sbjct 331 LVSQLRRDGVDPGAIRLGLFAGHYRQDRYWSPAVLDEAQQRLHRWRSATALDGAPDATDV 390 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VARVRRYLADDLDTPKA+AA+DGW D + YGGHD A V+ A+DALLGV L Sbjct 391 VARVRRYLADDLDTPKALAAIDGWAEDTLSYGGHDRTAGPTVSAAVDALLGVAL 444 >gi|254775033|ref|ZP_05216549.1| cysteinyl-tRNA synthetase [Mycobacterium avium subsp. avium ATCC 25291] Length=384 Score = 645 bits (1664), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/376 (84%), Positives = 346/376 (93%), Gaps = 3/376 (0%) Query 39 TMYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGV 98 TMYVCGITPYDATHLGHAATY+ FDLI+R WLDLGH++HYVQN+TD+DDPL ERA RDG+ Sbjct 12 TMYVCGITPYDATHLGHAATYLAFDLIYRQWLDLGHDVHYVQNVTDVDDPLLERAARDGI 71 Query 99 DWRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGE 158 DWR LA+ EV+LF EDMAALR+L P+DYVGATEAIA++VEL+EKMLA GAAYV+D GE Sbjct 72 DWRALAEREVSLFREDMAALRILAPRDYVGATEAIADVVELVEKMLASGAAYVVD---GE 128 Query 159 YQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSW 218 + DIY+RADATLQFGYESGYDR+TMLRL ERGGDP+RPGK+D LDALLWRAARPGEPSW Sbjct 129 FPDIYYRADATLQFGYESGYDRETMLRLFAERGGDPQRPGKTDALDALLWRAARPGEPSW 188 Query 219 PSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARH 278 PSPFG GRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECV GERRFARH Sbjct 189 PSPFGNGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVRGERRFARH 248 Query 279 YVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEA 338 YVHAGMIGWDGHKMSKSRGNLVLVS LR + VEP+A+RLGLLAGHYR DR+WS QVLDEA Sbjct 249 YVHAGMIGWDGHKMSKSRGNLVLVSQLRGRGVEPAAIRLGLLAGHYRGDRYWSDQVLDEA 308 Query 339 TARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGA 398 TARL RWRTATALPAGP A DV+ARVR+YLADDL+TPKA+AALDGW TDA++YGGHD A Sbjct 309 TARLRRWRTATALPAGPDATDVIARVRQYLADDLNTPKALAALDGWTTDALDYGGHDTAA 368 Query 399 PKLVATAIDALLGVDL 414 P+LVA+A+DALLGV L Sbjct 369 PRLVASAVDALLGVAL 384 >gi|118465539|ref|YP_881564.1| cysteinyl-tRNA synthetase [Mycobacterium avium 104] gi|310947192|sp|A0QF76.1|MSHC_MYCA1 RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|118166826|gb|ABK67723.1| cysteinyl-tRNA synthetase [Mycobacterium avium 104] Length=384 Score = 645 bits (1663), Expect = 0.0, Method: Compositional matrix adjust. Identities = 313/376 (84%), Positives = 346/376 (93%), Gaps = 3/376 (0%) Query 39 TMYVCGITPYDATHLGHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGV 98 TMYVCGITPYDATHLGHAATY+ FDLI+R WLDLGH++HYVQN+TD+DDPL ERA RDG+ Sbjct 12 TMYVCGITPYDATHLGHAATYLAFDLIYRQWLDLGHDVHYVQNVTDVDDPLLERAARDGI 71 Query 99 DWRDLAQAEVALFCEDMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGE 158 DWR LA+ EV+LF EDMAALR+L P+DYVGATEAIA++VEL+EKMLA GAAYV+D GE Sbjct 72 DWRALAEREVSLFREDMAALRILAPRDYVGATEAIADVVELVEKMLASGAAYVVD---GE 128 Query 159 YQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSW 218 + DIY+RADATLQFGYESGYDR+TMLRL ERGGDP+RPGK+D LDALLWRAARPGEPSW Sbjct 129 FPDIYYRADATLQFGYESGYDRETMLRLFAERGGDPQRPGKTDALDALLWRAARPGEPSW 188 Query 219 PSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARH 278 PSPFG GRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECV GERRFARH Sbjct 189 PSPFGNGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVRGERRFARH 248 Query 279 YVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEA 338 YVHAGMIGWDGHKMSKSRGNLVLVS LR + VEP+A+RLGLLAGH+R DR+WS QVLDEA Sbjct 249 YVHAGMIGWDGHKMSKSRGNLVLVSQLRGRGVEPAAIRLGLLAGHFRGDRYWSDQVLDEA 308 Query 339 TARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGA 398 TARL RWRTATALPAGP A DV+ARVR+YLADDL+TPKA+AALDGW TDA++YGGHD A Sbjct 309 TARLRRWRTATALPAGPDATDVIARVRQYLADDLNTPKALAALDGWTTDALDYGGHDTAA 368 Query 399 PKLVATAIDALLGVDL 414 P+LVATA+DALLGV L Sbjct 369 PRLVATAVDALLGVAL 384 >gi|169629202|ref|YP_001702851.1| cysteinyl-tRNA synthetase [Mycobacterium abscessus ATCC 19977] gi|310947193|sp|B1MPE6.1|MSHC_MYCA9 RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|169241169|emb|CAM62197.1| Cysteinyl-tRNA synthetase (CysS) [Mycobacterium abscessus] Length=412 Score = 625 bits (1612), Expect = 4e-177, Method: Compositional matrix adjust. Identities = 310/414 (75%), Positives = 345/414 (84%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW PVP L G GPQLRLYD+ADRQVRPV G ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWASAPVPELDGGGPQLRLYDTADRQVRPVTTGPTATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDLI+R WLD G ++HYVQN+TDIDDPLFERADRDG+DWR+L E LF DM ALRV Sbjct 61 TFDLIYRQWLDAGLDVHYVQNVTDIDDPLFERADRDGIDWRELGDRETELFRGDMTALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP++YV ATE+IA ++EL+EKMLA GAAYV+D EY D+YFR DAT QFGYESGYD Sbjct 121 LPPREYVRATESIACIIELVEKMLASGAAYVVDDP--EYPDVYFRVDATEQFGYESGYDI 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TM RL ERGGDP RPGK++ELDALLWRAARPGEPSW + FGPGRPGWHVEC+AI L Sbjct 179 ETMSRLFAERGGDPGRPGKANELDALLWRAARPGEPSWEASFGPGRPGWHVECSAIVLRE 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G+G+DIQGGGSDLIFPHHE++AAHAE V+ +RRFARHYVHAGMIGWDGHKMSKSRGNLV Sbjct 239 LGAGIDIQGGGSDLIFPHHEYSAAHAEAVTAQRRFARHYVHAGMIGWDGHKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS L AQ V+P+AVRLGLLAGHYRADR WS VL +A RL RWR A AL A P+A DV Sbjct 299 KVSGLTAQGVDPAAVRLGLLAGHYRADRSWSDAVLADAQGRLARWRHAVALSAAPSARDV 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VARVRRYLADDLDTP A+AALD WVTDA+ YGGHDA A V A+DALLGV L Sbjct 359 VARVRRYLADDLDTPNALAALDNWVTDALAYGGHDAAAGAQVRDAVDALLGVQL 412 >gi|312139693|ref|YP_004007029.1| mycothiol ligase mshc [Rhodococcus equi 103S] gi|325676858|ref|ZP_08156531.1| cysteine--tRNA ligase [Rhodococcus equi ATCC 33707] gi|311889032|emb|CBH48345.1| mycothiol ligase MshC [Rhodococcus equi 103S] gi|325552406|gb|EGD22095.1| cysteine--tRNA ligase [Rhodococcus equi ATCC 33707] Length=413 Score = 607 bits (1565), Expect = 1e-171, Method: Compositional matrix adjust. Identities = 297/414 (72%), Positives = 337/414 (82%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW VP +PG+GP LRLYD+ADRQVRPV PG+ A MYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSDTAVPSVPGQGPALRLYDTADRQVRPVTPGATAKMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL++R+ D GH +HYVQN+TD+DDPLFERADRDG DW L E ALF EDM ALRV Sbjct 61 TFDLVNRVLRDAGHAVHYVQNVTDVDDPLFERADRDGEDWVVLGMRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPPQDY+GA E+I E+VEL+EK +A GAAYV+D EY D+YFRADAT QFGYESGYDR Sbjct 121 LPPQDYIGAVESIGEVVELVEKFVASGAAYVVDDP--EYPDVYFRADATAQFGYESGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TM ERGGDP RPGK D LDAL+WRA RPGEPSWPSPFGPGRPGWH+ECAAIAL+R Sbjct 179 ATMDHFFAERGGDPNRPGKRDPLDALVWRAQRPGEPSWPSPFGPGRPGWHIECAAIALNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IGSG DIQGGGSDLIFPHHEF+AAHAE +G RFARHYVH GMIG DG KMSKSRGNLV Sbjct 239 IGSGFDIQGGGSDLIFPHHEFSAAHAESATGTDRFARHYVHTGMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR + V+P+A+RLGLL+GHYR DR W+ QVL +A RL WR A AL + P+A D Sbjct 299 FVSKLRGEGVDPAAIRLGLLSGHYRVDRPWTDQVLADAQERLALWRKAAALESAPSAEDT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VAR+R++LADDLDTPKA+ ALDGW AV++GG DAGAP A A+DALLGV+L Sbjct 359 VARLRQHLADDLDTPKALDALDGWARRAVDHGGPDAGAPGAFADAVDALLGVEL 412 >gi|226306683|ref|YP_002766643.1| cysteine--1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC [Rhodococcus erythropolis PR4] gi|310947210|sp|C0ZZW9.1|MSHC_RHOE4 RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|226185800|dbj|BAH33904.1| probable cysteine--1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC [Rhodococcus erythropolis PR4] Length=413 Score = 607 bits (1565), Expect = 1e-171, Method: Compositional matrix adjust. Identities = 289/414 (70%), Positives = 340/414 (83%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW +P +PG+GP LRLYD+ADRQVRPV PG KATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSDTALPSVPGQGPPLRLYDTADRQVRPVTPGKKATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL++R+W D GH++HYVQN+TD+DDPLFERA+RDG DW L E ALF EDM ALRV Sbjct 61 TFDLVNRIWRDAGHDVHYVQNVTDVDDPLFERANRDGEDWIVLGIRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP+DY+GA E++ E+VEL+EK +A GAAY++D E+ D+YFRADAT QFGYESGYDR Sbjct 121 LPPKDYIGAVESVNEVVELVEKFVASGAAYIVDD--AEFPDVYFRADATEQFGYESGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TM + ERGGDP R GK + LDAL+WRA RPGEPSWPSPFGPGRPGWH+ECAAIAL+R Sbjct 179 ATMEKFFAERGGDPDRVGKRNPLDALVWRAERPGEPSWPSPFGPGRPGWHIECAAIALNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IGSG D+QGGGSDLIFPHHEF+AAHAE +G+RRFARHYVH GMIG DG KMSKSRGNLV Sbjct 239 IGSGFDVQGGGSDLIFPHHEFSAAHAESATGDRRFARHYVHTGMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR + V+P+A+RLGLL+GHYR DR W+ QVL++A +RL WR A AL + P+A D Sbjct 299 FVSKLRGEGVDPAAIRLGLLSGHYRQDRAWTDQVLEDAQSRLKVWREAAALDSAPSATDT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VAR+R++LADDLDTPKA+ ALDGW A+E GG D AP A A+DALLG+ L Sbjct 359 VARLRQHLADDLDTPKALDALDGWARRAIEGGGSDTQAPGEFADAVDALLGISL 412 >gi|229494883|ref|ZP_04388636.1| cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Rhodococcus erythropolis SK121] gi|229318241|gb|EEN84109.1| cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Rhodococcus erythropolis SK121] Length=413 Score = 606 bits (1562), Expect = 2e-171, Method: Compositional matrix adjust. Identities = 289/414 (70%), Positives = 339/414 (82%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW +P +PG+GP LRLYD+ADRQVRPV PG KATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSDTALPSVPGQGPPLRLYDTADRQVRPVTPGEKATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL++R+W D GH++HYVQN+TD+DDPLFERA+RDG DW L E ALF EDM ALRV Sbjct 61 TFDLVNRIWRDAGHDVHYVQNVTDVDDPLFERANRDGEDWIVLGMRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP+DY+GA E++ E+VEL+EK +A GAAY++D E+ D+YFRADAT QFGYESGYDR Sbjct 121 LPPKDYIGAVESVNEVVELVEKFVASGAAYIVDD--AEFPDVYFRADATEQFGYESGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TM + ERGGDP R GK + LDAL+WRA RPGEPSWPSPFGPGRPGWH+ECAAIAL+R Sbjct 179 ATMEKFFAERGGDPDRVGKRNPLDALVWRAERPGEPSWPSPFGPGRPGWHIECAAIALNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IGSG D+QGGGSDLIFPHHEF+AAHAE +G+RRFARHYVH GMIG DG KMSKSRGNLV Sbjct 239 IGSGFDVQGGGSDLIFPHHEFSAAHAESATGDRRFARHYVHTGMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR + V+P+A+RLGLL+GHYR DR W+ QVL +A +RL WR A AL + P+A D Sbjct 299 FVSKLRGEGVDPAAIRLGLLSGHYRQDRAWTDQVLADAQSRLKVWREAAALGSAPSATDT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VAR+R++LADDLDTPKA+ ALDGW A+E GG D AP A A+DALLG+ L Sbjct 359 VARLRQHLADDLDTPKALDALDGWARRAIEGGGSDTQAPGEFADAVDALLGISL 412 >gi|111017896|ref|YP_700868.1| cysteinyl-tRNA synthetase [Rhodococcus jostii RHA1] gi|122956108|sp|Q0SIC6.1|MSHC_RHOSR RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|110817426|gb|ABG92710.1| cysteine--tRNA ligase [Rhodococcus jostii RHA1] Length=415 Score = 603 bits (1556), Expect = 1e-170, Method: Compositional matrix adjust. Identities = 284/414 (69%), Positives = 341/414 (83%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW VP +PG+GP LRL+D+ADRQVRPV PG ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSETAVPSVPGQGPPLRLFDTADRQVRPVTPGRTATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL++R+W D GH++HYVQN+TD+DDPLFERA+RDG DW L E ALF EDM ALRV Sbjct 61 TFDLVNRIWRDAGHDVHYVQNVTDVDDPLFERANRDGEDWVVLGMRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP+DY+GA E+I E++E++EK +A GAAYV+D E+ D+YFRA+AT QFGYESGYDR Sbjct 121 LPPRDYIGAVESIGEVIEMVEKFVASGAAYVVDDP--EFPDVYFRANATEQFGYESGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TM + ERGGDP RPGK D LDAL+WRA RPGEPSWPSPFGPGRPGWH+EC+AIAL+R Sbjct 179 ETMDKFFAERGGDPDRPGKEDPLDALVWRAVRPGEPSWPSPFGPGRPGWHIECSAIALNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IGSG D+QGGGSDLIFPHHE++AAHAE +G+RRFARHYVH GMIG DG KMSKSRGNLV Sbjct 239 IGSGFDVQGGGSDLIFPHHEYSAAHAESATGDRRFARHYVHTGMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR + V+P+A+RLGLL+GHYR DR W++Q+L +A RL W+ A AL + P+A D Sbjct 299 FVSKLRGEGVDPAAIRLGLLSGHYRQDRPWTEQLLADAHTRLQLWKDAAALESAPSATDT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 +AR+R++LADDLDTPKA+ ALDGW A+++GG D AP A A+DALLGV L Sbjct 359 IARLRQHLADDLDTPKALDALDGWARRALDHGGSDTNAPSEFAAAVDALLGVRL 412 >gi|226360027|ref|YP_002777805.1| cysteinyl-tRNA synthetase [Rhodococcus opacus B4] gi|310947211|sp|C1ASS8.1|MSHC_RHOOB RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|226238512|dbj|BAH48860.1| cysteine--1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC [Rhodococcus opacus B4] Length=415 Score = 600 bits (1546), Expect = 2e-169, Method: Compositional matrix adjust. Identities = 285/414 (69%), Positives = 338/414 (82%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW VP +PG+GP LRL+D+ADRQVRPV PG ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSETAVPSVPGQGPPLRLFDTADRQVRPVTPGRTATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL++R+W D GH++HYVQN+TD+DDPLFERA+RDG DW L E ALF EDM ALRV Sbjct 61 TFDLVNRIWRDAGHDVHYVQNVTDVDDPLFERANRDGEDWVVLGMRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP+DY+GA E+I E++E++EK +A GAAYV+D E+ D+YFRADAT QFGYESGYDR Sbjct 121 LPPRDYIGAVESIGEVIEMVEKFVASGAAYVVDDP--EFPDVYFRADATEQFGYESGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TM ERGGDP RPGK + LDAL+WRAARPGEPSWPSPFGPGRPGWH+EC+AIAL+R Sbjct 179 ATMDTFFAERGGDPDRPGKQNPLDALVWRAARPGEPSWPSPFGPGRPGWHIECSAIALNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IGSG D+QGGGSDLIFPHHE++AAHAE +G+RRFARHYVH GMIG DG KMSKSRGNLV Sbjct 239 IGSGFDVQGGGSDLIFPHHEYSAAHAESATGDRRFARHYVHTGMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR + V+P+A+RLGLL+GHYR DR W++QVL +A RL W+ A AL + +A D Sbjct 299 FVSKLRGEGVDPAAIRLGLLSGHYRQDRPWTEQVLADAHTRLQLWKDAAALESAQSATDT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 +AR+R++LADDLDTPKA+ ALDGW A++ GG D AP A A+DALLGV L Sbjct 359 IARLRQHLADDLDTPKALDALDGWARRALDNGGSDTNAPTEFAAAVDALLGVRL 412 >gi|54024903|ref|YP_119145.1| cysteinyl-tRNA synthetase [Nocardia farcinica IFM 10152] gi|61216443|sp|Q5YVL0.1|MSHC_NOCFA RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|54016411|dbj|BAD57781.1| putative ATP-dependent L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Nocardia farcinica IFM 10152] Length=412 Score = 587 bits (1513), Expect = 1e-165, Method: Compositional matrix adjust. Identities = 294/414 (72%), Positives = 347/414 (84%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW +P +PG GP LRLYD+ADRQVRPVAPG+ ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWSDTALPTVPGAGPPLRLYDTADRQVRPVAPGATATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDL++R+ D GH++HYVQN+TD+DDPLFERA RDGVDWR+L E+ LF DMAALRV Sbjct 61 TFDLVNRVLRDGGHDVHYVQNVTDVDDPLFERAARDGVDWRELGSREIELFRTDMAALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP++YVGA E++ E+VE ++K+LA GAAYV+D ++ DIYFR DAT QFGYESGYDR Sbjct 121 LPPREYVGAVESVEEVVEFVQKLLANGAAYVVDDP--DFPDIYFRTDATEQFGYESGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TM RL ERGGDP RPGK D LDALLWRAARPGEPSWP+PFG GRPGWH+EC+AIAL+R Sbjct 179 ATMERLFAERGGDPDRPGKRDPLDALLWRAARPGEPSWPAPFGAGRPGWHIECSAIALNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G DIQGGGSDLI+PHHE++AAHAE V RRFARHYVHAG+IG DG KMSKSRGNLV Sbjct 239 LGPEFDIQGGGSDLIYPHHEYSAAHAESVVAGRRFARHYVHAGLIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LR V+P+A+RLGLL GHYR DR W+ VL+ A ARL RWR+ATAL AGPAA D Sbjct 299 LVSTLRKDGVDPAAIRLGLLDGHYRQDRMWTDAVLEAALARLARWRSATALSAGPAAHDT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 +AR+R++LADDLD+PKA+AA+D WVT+A++YGG D+GAP +A A+DALLGV L Sbjct 359 IARLRQHLADDLDSPKALAAVDNWVTEALDYGGSDSGAPAAIAEAVDALLGVRL 412 >gi|343927961|ref|ZP_08767427.1| cysteine--1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC [Gordonia alkanivorans NBRC 16433] gi|343762184|dbj|GAA14353.1| cysteine--1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC [Gordonia alkanivorans NBRC 16433] Length=419 Score = 574 bits (1479), Expect = 1e-161, Method: Compositional matrix adjust. Identities = 281/412 (69%), Positives = 326/412 (80%), Gaps = 2/412 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW +P +PG GP LRLYD+ADR VRPV PG ATMYVCGITPYDATHLGHAATY+ Sbjct 4 MQSWPDVELPEVPGEGPALRLYDTADRAVRPVTPGRTATMYVCGITPYDATHLGHAATYL 63 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFD ++R+ D GH++HYVQN+TD+DDPLFERADRDGVDWRDL E LF +DM ALRV Sbjct 64 TFDQVNRVLRDQGHDVHYVQNVTDVDDPLFERADRDGVDWRDLGARETQLFRDDMTALRV 123 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP+DY+GA E+I E++E++EK+LA GAAY +D EY D+YFR DAT QFGYESGYDR Sbjct 124 LPPRDYIGAVESIGEVIEVVEKLLASGAAYTVDD--AEYPDVYFRTDATEQFGYESGYDR 181 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TM R ERGGDP R GK D LDALLWRA R GEPSW SPFGPGRPGWH+EC+AIAL+R Sbjct 182 ETMARFFAERGGDPDRAGKRDPLDALLWRAKREGEPSWDSPFGPGRPGWHIECSAIALNR 241 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G DIQGGG+DLIFPHHEF+AAH E ++ RRFARHYVH GM+G DG KMSKSRGNLV Sbjct 242 LGIEFDIQGGGNDLIFPHHEFSAAHGEALTDSRRFARHYVHTGMVGLDGEKMSKSRGNLV 301 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR + V+P+A+RL LLA HYR DR W+Q VLD A RL RWRTA A P GP A DV Sbjct 302 FVSVLRREGVDPAAIRLALLADHYRGDRMWTQSVLDTAVERLDRWRTAFAAPTGPDAADV 361 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGV 412 +ARVR++LADDLDTPKA+AA+D W D G A AP +A A+DALLG+ Sbjct 362 IARVRQHLADDLDTPKALAAVDAWCADVRSGIGSSAAAPATLAAAVDALLGI 413 >gi|296139847|ref|YP_003647090.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase [Tsukamurella paurometabola DSM 20162] gi|310947226|sp|D5UPJ5.1|MSHC_TSUPD RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|296027981|gb|ADG78751.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase [Tsukamurella paurometabola DSM 20162] Length=414 Score = 566 bits (1460), Expect = 2e-159, Method: Compositional matrix adjust. Identities = 278/412 (68%), Positives = 319/412 (78%), Gaps = 2/412 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 M+SW P VP L G LRLYD++D+ VR V PG+ + MYVCGITPYDATHLGHAATY+ Sbjct 1 MRSWPSPAVPTLSGPSVPLRLYDTSDQAVRSVNPGAVSGMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDLI+R+ GHE+HYVQN+TD+DDPLFERA RDG+DWRDL E LFCEDM ALRV Sbjct 61 TFDLINRVLRANGHEVHYVQNVTDVDDPLFERAARDGIDWRDLGARETDLFCEDMQALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 L PQDY+GA E+I E++ L+ ++L GAAY++D E+ D+Y+R DAT QFGYESGYDR Sbjct 121 LAPQDYIGAVESIDEVIALVGRLLENGAAYIVDDP--EFPDVYYRTDATEQFGYESGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TM R ERGGDP RPGK D LDALLWRAARPGEPSWPSP GPGRPGWH+ECAAIA +R Sbjct 179 ATMERFFAERGGDPDRPGKRDPLDALLWRAARPGEPSWPSPQGPGRPGWHIECAAIAQNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G G DIQGGGSDLIFPHHEF+AAH E +GERRFARHYVHA MIG DG KMSKSRGNLV Sbjct 239 LGVGFDIQGGGSDLIFPHHEFSAAHVEADTGERRFARHYVHAAMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR V+P+A+RLGL GHYR DR WS +VL A ARL WR A A + P ++ Sbjct 299 FVSTLRRAGVDPAAIRLGLFEGHYRTDRAWSDEVLARAQARLDLWRNAFAAASSPDGAEL 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGV 412 V R+RRYLADDLDTPKA++ALD W AV GG D P VATA+DALLGV Sbjct 359 VGRLRRYLADDLDTPKALSALDAWAHRAVTSGGPDPDGPSTVATAVDALLGV 410 >gi|262202368|ref|YP_003273576.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase [Gordonia bronchialis DSM 43247] gi|310947185|sp|D0LDR0.1|MSHC_GORB4 RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|262085715|gb|ACY21683.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase [Gordonia bronchialis DSM 43247] Length=413 Score = 555 bits (1430), Expect = 5e-156, Method: Compositional matrix adjust. Identities = 277/412 (68%), Positives = 323/412 (79%), Gaps = 2/412 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW P VP L G P LRLYD+ADR VRPVAPG AT+YVCGITPYDATHLGHAATYV Sbjct 1 MQSWPDPEVPKLSGDSPALRLYDTADRAVRPVAPGPTATLYVCGITPYDATHLGHAATYV 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFD ++R+ D GH++HYVQNITD+DDPLFERA+RDGVDWR+L ++ LF +DM ALRV Sbjct 61 TFDQVNRVLRDQGHDVHYVQNITDVDDPLFERAERDGVDWRELGSEQIQLFRDDMTALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP+DY+GA E++ E++E +EK+LA GAAYV+D EY D+YFR DAT QFGYESGYDR Sbjct 121 LPPRDYIGAMESVDEVIEAVEKLLASGAAYVVDDP--EYPDVYFRTDATEQFGYESGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TM R ERGGDP R GK D LDA+LWRAAR GEPSW +PFGPGRPGWH+EC+AIAL+R Sbjct 179 ATMARFFAERGGDPDRAGKRDPLDAVLWRAARDGEPSWEAPFGPGRPGWHIECSAIALNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G DIQGGG+DLIFPHHEF+AAH E ++ RRFARHYVH GM+G DG KMSKSRGNLV Sbjct 239 LGIEFDIQGGGNDLIFPHHEFSAAHGEALTDSRRFARHYVHTGMVGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR V+P+A+RL LLA HYR+DR W+ VL A RL RWRTA A PAGP A Sbjct 299 FVSVLRRDGVDPAAIRLALLADHYRSDRMWTDDVLATAVDRLQRWRTAAAAPAGPDAAPT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGV 412 VAR+R++LADDLDTPKA+ A+D W D G D AP +A A+DALLGV Sbjct 359 VARLRQHLADDLDTPKALDAVDAWCADVRTGIGSDPAAPAQIARAVDALLGV 410 >gi|296393640|ref|YP_003658524.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase [Segniliparus rotundus DSM 44985] gi|310947218|sp|D6ZFG9.1|MSHC_SEGRD RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|296180787|gb|ADG97693.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase [Segniliparus rotundus DSM 44985] Length=420 Score = 554 bits (1427), Expect = 1e-155, Method: Compositional matrix adjust. Identities = 282/420 (68%), Positives = 328/420 (79%), Gaps = 8/420 (1%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 M+SW P VP L G GP+LRL+DSADR +RPV PG ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MRSWLAPSVPKLAGAGPRLRLWDSADRIIRPVTPGRTATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL+HRLWLD GH++ Y QNITD+DDPL ERADRD DW++LA ++ LF DM+ALRV Sbjct 61 AFDLVHRLWLDAGHQVAYAQNITDVDDPLLERADRDHRDWQELAAEQIELFRTDMSALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP +YVG TE++ +V ++EK+LA +AYV+ GEY D+Y R AT FGY SGY R Sbjct 121 LPPHEYVGVTESVGLVVAMVEKLLANQSAYVVAE--GEYPDVYHRIAATEDFGYVSGYGR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 + M ++ ERGGDP RPGK+D LDALLWRAARPGEPSWPSPFGPGRPGWHVEC+AIAL R Sbjct 179 EEMAQVFRERGGDPDRPGKADPLDALLWRAARPGEPSWPSPFGPGRPGWHVECSAIALDR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSG------ERRFARHYVHAGMIGWDGHKMSK 294 IG G D+QGGGSDL+FPHHEF+AAHA+ G RRFAR+YVHAGMIG DG KMSK Sbjct 239 IGFGFDVQGGGSDLVFPHHEFSAAHAQAQHGAGAADEHRRFARNYVHAGMIGLDGEKMSK 298 Query 295 SRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAG 354 S GNLV VSALR + V+PSA+RL L AGHYRADR W Q +L EA RL RWR A +L +G Sbjct 299 SLGNLVFVSALRERGVDPSAIRLALFAGHYRADRSWDQGLLREAQERLARWRHAASLASG 358 Query 355 PAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 PAA DVVAR+R +LA+DLDTPKA+AALD W +A +GG D AP LVA A DALLGV L Sbjct 359 PAAHDVVARMREHLANDLDTPKALAALDSWSLEAAAHGGGDQEAPALVARAADALLGVQL 418 >gi|289447749|ref|ZP_06437493.1| cysteinyl-tRNA synthetase [Mycobacterium tuberculosis CPHL_A] gi|289420707|gb|EFD17908.1| cysteinyl-tRNA synthetase [Mycobacterium tuberculosis CPHL_A] Length=272 Score = 548 bits (1411), Expect = 9e-154, Method: Compositional matrix adjust. Identities = 272/272 (100%), Positives = 272/272 (100%), Gaps = 0/272 (0%) Query 143 MLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDE 202 MLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDE Sbjct 1 MLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCEERGGDPRRPGKSDE 60 Query 203 LDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFT 262 LDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFT Sbjct 61 LDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQGGGSDLIFPHHEFT 120 Query 263 AAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAG 322 AAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAG Sbjct 121 AAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQDVEPSAVRLGLLAG 180 Query 323 HYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALD 382 HYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALD Sbjct 181 HYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYLADDLDTPKAIAALD 240 Query 383 GWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 GWVTDAVEYGGHDAGAPKLVATAIDALLGVDL Sbjct 241 GWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 272 >gi|333919628|ref|YP_004493209.1| L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Amycolicicoccus subflavus DQS3-9A1] gi|333481849|gb|AEF40409.1| L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Amycolicicoccus subflavus DQS3-9A1] Length=423 Score = 543 bits (1399), Expect = 2e-152, Method: Compositional matrix adjust. Identities = 275/421 (66%), Positives = 325/421 (78%), Gaps = 9/421 (2%) Query 1 MQSWYCPPVPV---LPG----RGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHL 53 M SW P +P LPG GP LRLYD+ADR +RPV PG ATMYVCGITPYDATHL Sbjct 4 MLSWSAPELPSVGDLPGGLRESGPVLRLYDTADRAIRPVNPGQTATMYVCGITPYDATHL 63 Query 54 GHAATYVTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCE 113 GHAATY+TFD+I+R+ GH++HYVQN+TD+DDPLFERA+RDG DW L E ALF E Sbjct 64 GHAATYLTFDVINRILRAQGHDVHYVQNVTDVDDPLFERANRDGEDWVVLGMRETALFRE 123 Query 114 DMAALRVLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFG 173 DM ALRVLPP+DY+GA E++ E++E++EK++A GAAYV+D ++ D+YF DAT+QFG Sbjct 124 DMEALRVLPPRDYIGAVESMGEVIEMVEKLMASGAAYVVDDP--DFPDVYFPIDATVQFG 181 Query 174 YESGYDRDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVEC 233 YESGYD TM + ERGGDP RPGK LDAL+WRAAR GEPSW SPFG GRPGWH+EC Sbjct 182 YESGYDDVTMRKFFAERGGDPDRPGKRHPLDALIWRAAREGEPSWESPFGAGRPGWHIEC 241 Query 234 AAIALSRIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMS 293 +AIAL+RIG+G DIQGGGSDLIFPHHEF+AAHAE +G R ARHY+H GMIG DG KMS Sbjct 242 SAIALNRIGTGFDIQGGGSDLIFPHHEFSAAHAEAATGSERMARHYIHTGMIGLDGAKMS 301 Query 294 KSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPA 353 KSRGNLV VS LR + V P+A+RL LL GHYRADR W+ ++L +A RL WR A A P+ Sbjct 302 KSRGNLVFVSKLRGEGVNPAAIRLALLDGHYRADRSWTAELLHQAERRLALWRAAAARPS 361 Query 354 GPAAVDVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVD 413 GP A DV+ARVR++LADDLDTPKAIAALD W +AV GG AP+ VA DALLG+ Sbjct 362 GPPADDVLARVRQHLADDLDTPKAIAALDFWADEAVARGGSSRSAPRDVALITDALLGIS 421 Query 414 L 414 L Sbjct 422 L 422 >gi|257056227|ref|YP_003134059.1| cysteinyl-tRNA synthetase [Saccharomonospora viridis DSM 43017] gi|310947214|sp|C7MWX8.1|MSHC_SACVD RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|256586099|gb|ACU97232.1| cysteinyl-tRNA synthetase [Saccharomonospora viridis DSM 43017] Length=415 Score = 541 bits (1394), Expect = 7e-152, Method: Compositional matrix adjust. Identities = 269/417 (65%), Positives = 317/417 (77%), Gaps = 5/417 (1%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQ+W VP +PG LRLYD+A Q+RP APG A MYVCGITPYDATHLGHAATY+ Sbjct 1 MQTWSSVAVPRVPGTSRPLRLYDTATGQIRPTAPGRVAKMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL+HRLWLD GHE+HYVQN+TDIDDPL ERA+RD DW L E ALF EDM ALRV Sbjct 61 AFDLVHRLWLDAGHEVHYVQNVTDIDDPLLERAERDSEDWVVLGLRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP+D+VGA E+I E+VE+IEK+LA GAAY +D EY D+YF T +FGYES YD Sbjct 121 LPPRDFVGAVESIPEVVEMIEKLLASGAAYRVDDP--EYPDVYFDRSFTGRFGYESNYDD 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TM + ERGGDP RPGK D LDALLWR RPGEP+W S G GRPGWH+EC+AIAL Sbjct 179 ETMRAIFPERGGDPDRPGKRDPLDALLWRVERPGEPAWDSSLGRGRPGWHIECSAIALKH 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G G D+QGGGSDL+FPHHEF+AAHAE ++GE FARHYVHAGMIG DG KMSKS+GNLV Sbjct 239 LGIGFDVQGGGSDLVFPHHEFSAAHAEAMTGEHPFARHYVHAGMIGLDGEKMSKSKGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LRA DV+PSA+RL L AGHYR DR W+ ++L +A +RL RWR A +LP+GP A Sbjct 299 FVSRLRADDVDPSAIRLALFAGHYRDDREWTDELLKQANSRLARWREAVSLPSGPDAEAT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAG---APKLVATAIDALLGVDL 414 V R+R +LADDLDTPKA+AA+D WV +A+ + G AP LV A+D+LLGV L Sbjct 359 VDRLRDHLADDLDTPKALAAVDAWVDEALRHRSGTVGSESAPALVRAAVDSLLGVVL 415 >gi|256376329|ref|YP_003099989.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase [Actinosynnema mirum DSM 43827] gi|310947170|sp|C6WIA0.1|MSHC_ACTMD RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|255920632|gb|ACU36143.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase [Actinosynnema mirum DSM 43827] Length=412 Score = 527 bits (1357), Expect = 1e-147, Method: Compositional matrix adjust. Identities = 260/414 (63%), Positives = 313/414 (76%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQ+W P VP L G LRL+D+A +VRP APG A +YVCGITPYDATHLGHAATY+ Sbjct 1 MQTWSSPSVPKLRGAPRPLRLHDTATGEVRPTAPGDTARLYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL+ R+WLD GH++HYVQN+TD+DDPL ERA RD DW LA E ALF EDM ALRV Sbjct 61 AFDLVQRVWLDNGHDVHYVQNVTDVDDPLLERAARDQDDWVVLAMRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 L P++YVGA E+I +V++IEK+LA GAAY +D + EY D+YF DAT FGYES YDR Sbjct 121 LAPREYVGAVESIPGIVDMIEKLLASGAAYRLDDD--EYPDVYFPHDATPNFGYESNYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TMLRL ERGGDP RPGK D LDALLWR ARPGEPSW + G GRPGWH+EC+ IAL+ Sbjct 179 ETMLRLFAERGGDPDRPGKRDPLDALLWRMARPGEPSWETSIGTGRPGWHIECSHIALAN 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 + + D+QGGGSDL+FPHHE++AAHAE ++G+ FARHY HAGMIG DG KMSKSRGNLV Sbjct 239 LDTPFDLQGGGSDLVFPHHEYSAAHAEALTGQHPFARHYAHAGMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR+ V+P +RL L AGHYR DR W+ ++ EA RL WR+A L +GP+ DV Sbjct 299 FVSKLRSTGVDPGVIRLALFAGHYREDRPWTDELFAEAGTRLALWRSAADLESGPSVDDV 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VARVR +L +DLDTPKA+AALD W +A + GG D AP + TA+DALLG+ L Sbjct 359 VARVREHLGNDLDTPKALAALDAWAREAWDRGGPDTEAPGVFRTAVDALLGIAL 412 >gi|326382269|ref|ZP_08203961.1| cysteinyl-tRNA synthetase [Gordonia neofelifaecis NRRL B-59395] gi|326198999|gb|EGD56181.1| cysteinyl-tRNA synthetase [Gordonia neofelifaecis NRRL B-59395] Length=416 Score = 526 bits (1354), Expect = 3e-147, Method: Compositional matrix adjust. Identities = 267/414 (65%), Positives = 318/414 (77%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 M SW P +P +PG LRLYD++D QV+PV+PG ATMYVCGITPYDATHLGHAATYV Sbjct 1 MHSWPSPQIPSVPGPAVPLRLYDTSDAQVKPVSPGEVATMYVCGITPYDATHLGHAATYV 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 TFDLI+R+ D GH++HYVQNITD+DDPLFERA+RDGVDWRDL E+ LF DM ALRV Sbjct 61 TFDLINRVLRDGGHDVHYVQNITDVDDPLFERAERDGVDWRDLGAREIDLFRADMTALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 L P+DY+GA E+I E+++ + K+LA G+AYV+D E+ D+YF DAT QFGYESGYD Sbjct 121 LAPRDYIGAVESIDEVIDAVGKLLANGSAYVVDDP--EFPDVYFSVDATPQFGYESGYDG 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TM + ERGGDP R GK + LDAL+WRAAR GEPSW SP GPGRPGWH+EC+AIAL+R Sbjct 179 ETMAKFFAERGGDPDRAGKRNPLDALVWRAARDGEPSWESPMGPGRPGWHIECSAIALNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G DIQGGGSDLIFPHHEF+AAH E ++GERRFARHYVH GMIG DG KMSKS GNLV Sbjct 239 LGMAFDIQGGGSDLIFPHHEFSAAHGEALTGERRFARHYVHTGMIGLDGEKMSKSLGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 LVS LRA V+ AVRLGL++ HYRADR W+ +L + RL WR A GP A Sbjct 299 LVSKLRAAGVDAGAVRLGLMSQHYRADRMWTDDILTDGERRLATWRRAAKHATGPDATAT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VAR+R++L+DDLDT KAIAA+D W DA+ G AP L+ A+DALLGVD+ Sbjct 359 VARLRQHLSDDLDTAKAIAAVDAWAADAILGIGSSETAPALIIDAVDALLGVDI 412 >gi|324997324|ref|ZP_08118436.1| cysteinyl-tRNA synthetase [Pseudonocardia sp. P1] Length=412 Score = 522 bits (1344), Expect = 6e-146, Method: Compositional matrix adjust. Identities = 260/414 (63%), Positives = 311/414 (76%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 M++W VP L G GP LRL+D+A +VRP APG ATMYVCGITPYDATHLGHAATY+ Sbjct 1 METWAPTDVPALEGSGPPLRLHDTATGRVRPTAPGPVATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL++RLW DLGHE+HYVQN+TDID+PL ERA+RD DW L E ALF EDM ALRV Sbjct 61 AFDLVNRLWRDLGHEVHYVQNVTDIDEPLLERAERDQDDWVVLGLRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP+ +VGA EAI E+ EL+EK++A GAAY +D EY D+Y AT +FGYES YD Sbjct 121 LPPRQFVGAVEAIPEIAELVEKLVASGAAYRLDDP--EYPDVYHDVSATGRFGYESNYDL 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TML+ ERGGDP RPGK + LD LLWR ARPGEP+W S G GRPGWHVECAAI L+R Sbjct 179 ETMLQFSRERGGDPDRPGKRNPLDPLLWRMARPGEPAWESGLGRGRPGWHVECAAIGLNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G +D+ GGGSDLIFPHHE A HAE ++GE FARHYVH GMIG DG KMSKS+GNLV Sbjct 239 LGQQIDLNGGGSDLIFPHHECGALHAESLTGEHPFARHYVHTGMIGLDGEKMSKSKGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR+ V+P+ VR+ LL GHYR DR W+ +V + R+ RWR A L AGP A ++ Sbjct 299 FVSKLRSSGVDPNVVRVALLDGHYRDDRSWTDEVHAKGEGRVARWREAVELDAGPDAAEL 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VA++R +LADDLDTP A+AA+D W +A+ G DAGAP+L TA+DALLGV L Sbjct 359 VAKLRTHLADDLDTPGALAAVDAWADEALTRRGTDAGAPQLARTALDALLGVRL 412 >gi|302527180|ref|ZP_07279522.1| cysteine-1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Streptomyces sp. AA4] gi|302436075|gb|EFL07891.1| cysteine-1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Streptomyces sp. AA4] Length=412 Score = 521 bits (1341), Expect = 1e-145, Method: Compositional matrix adjust. Identities = 265/414 (65%), Positives = 315/414 (77%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQ+W VP LPG LRL+D+A QVRP APG+ A MYVCGITPYDATHLGHAATY+ Sbjct 1 MQTWSSVAVPRLPGTPRPLRLHDTATGQVRPTAPGAAARMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL++R+W D GHE+HYVQN+TDID+PL ERA+RD DW L E ALF EDM ALRV Sbjct 61 AFDLVNRIWRDNGHEVHYVQNVTDIDEPLLERAERDSDDWIVLGMRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPP+ +VGA EAI E+VE+I K+LA G+AY D E+ D+YF +AT +FGYES YD Sbjct 121 LPPRQFVGAVEAIPEIVEVIAKLLADGSAYRADD--AEFPDVYFDHNATGRFGYESSYDA 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TM + ERGGDP RPGK LDALLWR AR GEPSW S G GRPGWH+EC+AIA++R Sbjct 179 ETMAKFFAERGGDPDRPGKRHPLDALLWRVAREGEPSWESELGAGRPGWHIECSAIAVNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G G D+QGGGSDLIFPHHE++AAHAE V+ + FARHYVHAGMIG DG KMSKSRGNLV Sbjct 239 LGLGFDVQGGGSDLIFPHHEYSAAHAEAVAADHPFARHYVHAGMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LRA V+P+A+RL L AGHYR DR W+ Q+L +A RL RWR A ALPAGP A D Sbjct 299 FVSRLRADGVDPAAIRLALFAGHYREDRAWTDQLLVDAQERLARWREAVALPAGPDAEDT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VAR+R +L+DDL+TPKA+ A+D WVT A+ G D AP L+ A+DALLG+ L Sbjct 359 VARLRDHLSDDLNTPKALTAIDAWVTSALRRDGTDQAAPGLIKEAVDALLGIVL 412 >gi|134098795|ref|YP_001104456.1| cysteinyl-tRNA synthetase [Saccharopolyspora erythraea NRRL 2338] gi|310947213|sp|A4FBV6.1|MSHC_SACEN RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|133911418|emb|CAM01531.1| cysteinyl-tRNA synthetase [Saccharopolyspora erythraea NRRL 2338] Length=412 Score = 520 bits (1339), Expect = 2e-145, Method: Compositional matrix adjust. Identities = 259/414 (63%), Positives = 307/414 (75%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQ W PVP +PG LRL+D+A +VRPV G A MYVCGITPYDATHLGHAATY+ Sbjct 1 MQPWSSVPVPKVPGTARPLRLFDTAAGEVRPVTAGRTARMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL+HR+WLD GH++HYVQN+TDIDDPL ERA+RD DW LA E ALF EDM ALRV Sbjct 61 AFDLVHRIWLDNGHDVHYVQNVTDIDDPLLERANRDNEDWVVLAMRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 +PP D++GA E+I E+ E + K+LA GAAY +D + EY D+YFR AT +FGYES YD Sbjct 121 VPPTDFIGAVESIPEIEEAVGKLLASGAAYRVDDD--EYPDVYFRHSATGRFGYESNYDE 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TML L ERGGDP R GK LDALLWR AR GEPSW S GPGRPGWH+EC+ IAL+R Sbjct 179 ATMLDLSAERGGDPDRKGKEHPLDALLWRMARDGEPSWESELGPGRPGWHLECSVIALNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G G D+QGGGSDL FPHHEF+AAHAE ++G+ FARHY HAGMIG DG KMSKS+GNLV Sbjct 239 LGMGFDVQGGGSDLAFPHHEFSAAHAEALAGDHPFARHYCHAGMIGLDGEKMSKSKGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LR V+P A+RL LL GHYR+DR W+ L + +ARL RWR A AL AGP+A V Sbjct 299 FVSRLRGDRVDPMAIRLALLDGHYRSDRSWTADALTKGSARLARWREAVALEAGPSAEPV 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 V R+R L+DDLDT +A+ A+D WV +A+ G DA AP + A+D LLGV L Sbjct 359 VERLRDRLSDDLDTERALLAVDAWVDEALCRRGGDAEAPAAIRDAVDGLLGVQL 412 >gi|300786807|ref|YP_003767098.1| cysteinyl-tRNA synthetase [Amycolatopsis mediterranei U32] gi|299796321|gb|ADJ46696.1| cysteinyl-tRNA synthetase [Amycolatopsis mediterranei U32] gi|340528292|gb|AEK43497.1| cysteinyl-tRNA synthetase [Amycolatopsis mediterranei S699] Length=412 Score = 520 bits (1338), Expect = 3e-145, Method: Compositional matrix adjust. Identities = 257/414 (63%), Positives = 310/414 (75%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQ+W VP +PG LRL+D+A Q+RP APG+ A MYVCGITPYDATHLGHAATY+ Sbjct 1 MQTWSSVDVPRIPGTPRPLRLHDTATGQIRPTAPGATARMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL++R+W D GH++HYVQN+TDID+PL ERA RD DW L E ALF EDM ALRV Sbjct 61 AFDLVNRIWRDNGHDVHYVQNVTDIDEPLLERAARDQGDWVVLGMRETALFREDMTALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 +PP+ +VGA E+I E+VE+I K+LA G+AY E+ DIYF AT +FGYES YD Sbjct 121 IPPRQFVGAVESIPEIVEVIAKLLANGSAYRAGDP--EFPDIYFDHTATGRFGYESNYDA 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 +TM + ERGGDP R GK LDALLWR AR GEPSW S GPGRPGWH+EC+AIA++R Sbjct 179 ETMAKFFAERGGDPGRAGKRHPLDALLWRVAREGEPSWESELGPGRPGWHIECSAIAVNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G G D+QGGGSDLIFPHHE++AAHAE V+ + RFARHYVHAGMIG DG KMSKSRGNLV Sbjct 239 LGLGFDLQGGGSDLIFPHHEYSAAHAEAVAKDGRFARHYVHAGMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LRA V+P A+RL L AGHYR DR W+ ++L +A RL RWR A AL GPAA D Sbjct 299 FVSRLRADQVDPGAIRLALFAGHYRDDRPWTDRLLTDAETRLARWREAVALATGPAAEDT 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 V R+R +L+D+LDTPKA+AA+D W +A+ G D AP L+ A+DALLG+ L Sbjct 359 VTRLRDHLSDNLDTPKALAAIDAWANEALRRDGTDPTAPGLIRDAVDALLGIAL 412 >gi|331697134|ref|YP_004333373.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Pseudonocardia dioxanivorans CB1190] gi|326951823|gb|AEA25520.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Pseudonocardia dioxanivorans CB1190] Length=412 Score = 511 bits (1316), Expect = 9e-143, Method: Compositional matrix adjust. Identities = 263/414 (64%), Positives = 307/414 (75%), Gaps = 2/414 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQ W VP L G GP LRL+D++ +VRP APG +ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQPWAPVDVPRLEGSGPPLRLHDTSTGRVRPTAPGPEATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL++R W DLGH++HYVQN+TDIDDPL ERA RD DW L E ALF EDM ALRV Sbjct 61 AFDLVNRYWRDLGHDVHYVQNVTDIDDPLLERAARDQDDWVVLGMRETALFREDMEALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 +PP+ Y+GA EA+ E+ E + K+LA G+AY ID E+ D+YF + A+ FGYES YD Sbjct 121 VPPRHYIGAVEAMGEIAEFVGKLLAGGSAYRIDDP--EFPDVYFDSTASGHFGYESNYDE 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TM+ L ERGGDP RPGK DALLWR AR GEPSW S G GRPGWHVECAAIAL+R Sbjct 179 QTMIALSRERGGDPDRPGKRHPADALLWRMAREGEPSWESDLGAGRPGWHVECAAIALNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 +G +D+ GGGSDLIFPHHEF AAHAE +G FARHYVH GMIG DG KMSKSRGNLV Sbjct 239 LGDQIDLNGGGSDLIFPHHEFGAAHAEAHTGVHPFARHYVHTGMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS LRA DV+P+AVRL LL+GHYR DR W+ +L+ A RL RWR A L AGP A + Sbjct 299 FVSKLRADDVDPNAVRLALLSGHYRTDRAWTDDLLEAAQQRLARWREAVTLDAGPDATET 358 Query 361 VARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 VA +R +LADDLDTP+A+AA+D W A+E G DA AP + TA+DALLGV L Sbjct 359 VANLRAHLADDLDTPRALAAVDAWAGAALERRGTDAAAPATIRTAVDALLGVKL 412 >gi|291005851|ref|ZP_06563824.1| cysteinyl-tRNA synthetase [Saccharopolyspora erythraea NRRL 2338] Length=404 Score = 510 bits (1314), Expect = 1e-142, Method: Compositional matrix adjust. Identities = 254/406 (63%), Positives = 303/406 (75%), Gaps = 2/406 (0%) Query 9 VPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYVTFDLIHRL 68 +P +PG LRL+D+A +VRPV G A MYVCGITPYDATHLGHAATY+ FDL+HR+ Sbjct 1 MPKVPGTARPLRLFDTAAGEVRPVTAGRTARMYVCGITPYDATHLGHAATYLAFDLVHRI 60 Query 69 WLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRVLPPQDYVG 128 WLD GH++HYVQN+TDIDDPL ERA+RD DW LA E ALF EDM ALRV+PP D++G Sbjct 61 WLDNGHDVHYVQNVTDIDDPLLERANRDNEDWVVLAMRETALFREDMEALRVVPPTDFIG 120 Query 129 ATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDRDTMLRLCE 188 A E+I E+ E + K+LA GAAY +D + EY D+YFR AT +FGYES YD TML L Sbjct 121 AVESIPEIEEAVGKLLASGAAYRVDDD--EYPDVYFRHSATGRFGYESNYDEATMLDLSA 178 Query 189 ERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSRIGSGLDIQ 248 ERGGDP R GK LDALLWR AR GEPSW S GPGRPGWH+EC+ IAL+R+G G D+Q Sbjct 179 ERGGDPDRKGKEHPLDALLWRMARDGEPSWESELGPGRPGWHLECSVIALNRLGMGFDVQ 238 Query 249 GGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLVLVSALRAQ 308 GGGSDL FPHHEF+AAHAE ++G+ FARHY HAGMIG DG KMSKS+GNLV VS LR Sbjct 239 GGGSDLAFPHHEFSAAHAEALAGDHPFARHYCHAGMIGLDGEKMSKSKGNLVFVSRLRGD 298 Query 309 DVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDVVARVRRYL 368 V+P A+RL LL GHYR+DR W+ L + +ARL RWR A AL AGP+A VV R+R L Sbjct 299 RVDPMAIRLALLDGHYRSDRSWTADALTKGSARLARWREAVALEAGPSAEPVVERLRDRL 358 Query 369 ADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGVDL 414 +DDLDT +A+ A+D WV +A+ G DA AP + A+D LLGV L Sbjct 359 SDDLDTERALLAVDAWVDEALCRRGGDAEAPAAIRDAVDGLLGVQL 404 >gi|317506755|ref|ZP_07964536.1| cysteine-1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Segniliparus rugosus ATCC BAA-974] gi|316254954|gb|EFV14243.1| cysteine-1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Segniliparus rugosus ATCC BAA-974] Length=354 Score = 496 bits (1278), Expect = 2e-138, Method: Compositional matrix adjust. Identities = 247/355 (70%), Positives = 278/355 (79%), Gaps = 11/355 (3%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 M+SW P VP L G GPQLRL+DSADR +RPVAPG KA MYVCGITPYDATHLGHAATY+ Sbjct 1 MRSWPTPLVPKLEGVGPQLRLWDSADRLLRPVAPGRKAGMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL+ RLWLD GHE+HY QNITD+DDPL ERA+RD DWR LA ++ LF DMAALRV Sbjct 61 AFDLVCRLWLDAGHEVHYTQNITDVDDPLLERAERDDRDWRALAAEQIELFRTDMAALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 LPPQDYVG TE+I +V ++EK+LA +AYV+ GEY D+Y R AT FGY SGYDR Sbjct 121 LPPQDYVGVTESIDLVVAMVEKLLANQSAYVVAE--GEYPDVYHRVGATEDFGYVSGYDR 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 D M R+ ERGGDP RPGK+D LDALLWRAARPGEPSWPSPFGPGRPGWHVEC+AIAL R Sbjct 179 DEMTRVFRERGGDPDRPGKADPLDALLWRAARPGEPSWPSPFGPGRPGWHVECSAIALDR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAEC---------VSGERRFARHYVHAGMIGWDGHK 291 IG G D+QGGG+DL+FPHHEF+AAHA+ G RFAR+YVHAGMIG DG K Sbjct 239 IGFGFDVQGGGADLVFPHHEFSAAHAQAQVGGCSVPGADGRGRFARNYVHAGMIGLDGEK 298 Query 292 MSKSRGNLVLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWR 346 MSKS GNLV VS LRA V+PSA+RL L AGHYRADR W Q +L +A ARL RWR Sbjct 299 MSKSLGNLVFVSKLRAAGVDPSAIRLALFAGHYRADRSWDQNLLAQAQARLSRWR 353 >gi|258652959|ref|YP_003202115.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase [Nakamurella multipartita DSM 44233] gi|310947206|sp|C8X8S1.1|MSHC_NAKMY RecName: Full=L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Short=L-Cys:GlcN-Ins ligase; AltName: Full=Mycothiol ligase; Short=MSH ligase gi|258556184|gb|ACV79126.1| cysteine/1-D-myo-inosityl 2-amino-2-deoxy-alpha- D-glucopyranoside ligase [Nakamurella multipartita DSM 44233] Length=405 Score = 490 bits (1262), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 254/387 (66%), Positives = 287/387 (75%), Gaps = 3/387 (0%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPVAPGSKATMYVCGITPYDATHLGHAATYV 60 MQSW PPVP +PG G LRLYDSA +VRP PG ATMYVCGITPYDATHLGHAATY+ Sbjct 1 MQSWPSPPVPGIPGTGRPLRLYDSATGEVRPTDPGPVATMYVCGITPYDATHLGHAATYL 60 Query 61 TFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALRV 120 FDL+HR+WLD GH++HYVQNITDIDDPL ERA RDGV WR LA E+ LF +DM ALRV Sbjct 61 AFDLVHRMWLDAGHQVHYVQNITDIDDPLLERAQRDGVSWRKLADREIGLFRDDMTALRV 120 Query 121 LPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYDR 180 +PP DY+GA EA+ E+ +++++ GAAY + E +Y D+YF A+ QFGYES YD Sbjct 121 IPPADYIGAVEAMDEVTAAVQELIDAGAAYRVPDE--QYPDVYFDVTASGQFGYESRYDE 178 Query 181 DTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALSR 240 TMLRL ERGGDP RPGK LD LLWR RP EPSW SP GPGRPGWH+ECA IA +R Sbjct 179 ATMLRLSAERGGDPDRPGKRQRLDPLLWRVERPQEPSWSSPMGPGRPGWHIECAVIAGNR 238 Query 241 IGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNLV 300 IG +D+QGGGSDLIFPHHE +AAHAE +SG+R FARHY HAGMIG DG KMSKSRGNLV Sbjct 239 IGPVIDLQGGGSDLIFPHHECSAAHAEVLSGKRPFARHYTHAGMIGLDGEKMSKSRGNLV 298 Query 301 LVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVDV 360 VS L Q V+P A+RLGLLAGHYR DR WS +VL A ARL R A A G A V Sbjct 299 FVSRLLHQGVDPMAMRLGLLAGHYRQDRAWSDEVLTAAEARLAR-WRAAAARTGVDADSV 357 Query 361 VARVRRYLADDLDTPKAIAALDGWVTD 387 V +R LADDLDTP I ALD W D Sbjct 358 VQAIRDGLADDLDTPTVIEALDAWAAD 384 >gi|296117896|ref|ZP_06836479.1| cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Corynebacterium ammoniagenes DSM 20306] gi|295969127|gb|EFG82369.1| cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Corynebacterium ammoniagenes DSM 20306] Length=420 Score = 486 bits (1252), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 249/424 (59%), Positives = 295/424 (70%), Gaps = 19/424 (4%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPV-APGSKATMYVCGITPYDATHLGHAATY 59 M+SW P VP +PG L+LYDSAD +++PV G ATMYVCGITPYD+THLGHAATY Sbjct 1 MKSWPIPSVPSVPGSAASLKLYDSADEKIKPVRVEGDTATMYVCGITPYDSTHLGHAATY 60 Query 60 VTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALR 119 VTFD+I+R+ D GH++HYVQNITD+DDPLFERA+RDGVDWR+L +++V LF DM L Sbjct 61 VTFDVIYRMLQDQGHKVHYVQNITDVDDPLFERAERDGVDWRELGESQVDLFRSDMEQLG 120 Query 120 VLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYD 179 V PPQDY+GA E+I E+++L +K+L GAAY +D +Y D+Y DAT QFGYES YD Sbjct 121 VYPPQDYIGAIESIDEVIDLTQKLLDNGAAYAVDD--AKYPDVYASVDATSQFGYESNYD 178 Query 180 RDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALS 239 R+TM + ERGGDP R GK D LDALLWRAAR GEPSW SPFG GRPGWHVEC+AIA + Sbjct 179 RETMEKFFAERGGDPDREGKKDPLDALLWRAAREGEPSWESPFGAGRPGWHVECSAIATN 238 Query 240 RIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNL 299 R+GS IQGGGSDL +PHHE++AAHAE G R A YVHAGMIG DG KMSKS GNL Sbjct 239 RLGSSFLIQGGGSDLKYPHHEYSAAHAEAGLGVDRMAEFYVHAGMIGLDGTKMSKSLGNL 298 Query 300 VLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAV- 358 V V L Q E SA+RLGL A HYR DR WS +VL A RL+ WRTA A A Sbjct 299 VFVHKLVEQGAEASAIRLGLYAHHYRGDRDWSDEVLSTAVERLNTWRTAVAETDDADASI 358 Query 359 ----------DVVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDA 408 + V +R YLA+DLDT A+ +D W A A +VATA+D Sbjct 359 DAAAAQQAAEETVQALREYLANDLDTVGALNVIDEWAKKPTT-----AEAAGVVATAVDG 413 Query 409 LLGV 412 LLGV Sbjct 414 LLGV 417 >gi|255325703|ref|ZP_05366800.1| cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Corynebacterium tuberculostearicum SK141] gi|255297313|gb|EET76633.1| cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [Corynebacterium tuberculostearicum SK141] Length=415 Score = 486 bits (1251), Expect = 3e-135, Method: Compositional matrix adjust. Identities = 245/414 (60%), Positives = 299/414 (73%), Gaps = 6/414 (1%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPV-APGSKATMYVCGITPYDATHLGHAATY 59 M SW P +PG QLRLYDSA++ + PV G ATMYVCGITPYD+THLGHAATY Sbjct 4 MHSWPTPSFRPVPGDAAQLRLYDSANQTIAPVEVAGDTATMYVCGITPYDSTHLGHAATY 63 Query 60 VTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALR 119 +TFDLI+R +LD G ++HYVQNITD+DDPLFERA+RDGVDWR+L +++ LF DM L Sbjct 64 LTFDLIYRAFLDAGKKVHYVQNITDVDDPLFERAERDGVDWRELGTSQIDLFRSDMELLS 123 Query 120 VLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYD 179 V PPQDY+GA EA+ E+VE+++K+L GAAYV+D E+ DIY +AT +FGYES Y Sbjct 124 VFPPQDYIGAMEAVDEIVEMVQKLLDAGAAYVVDDP--EHPDIYASIEATERFGYESNYS 181 Query 180 RDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALS 239 + M ERGGDP RPGK + LDAL+WRA R GEP+W SPFGPGRPGWH+EC+AIA + Sbjct 182 AEEMRTFFAERGGDPDRPGKKNPLDALIWRAHREGEPAWDSPFGPGRPGWHIECSAIATN 241 Query 240 RIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNL 299 R+GS DIQGGGSDL FPHHEF+AAHAE R A+ YVH GMIG DG KMSKS GNL Sbjct 242 RLGSTFDIQGGGSDLKFPHHEFSAAHAEAALNVERMAQFYVHTGMIGLDGVKMSKSLGNL 301 Query 300 VLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVD 359 V V L +PSA+RLG+ AGHYR +R WS +VLD A RL WR A A P A + Sbjct 302 VFVHKLVGAGEDPSAIRLGVFAGHYRDERDWSDEVLDAAKRRLAAWREALAQPGSMAGAE 361 Query 360 -VVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGV 412 VVA++R +A+DLDTP A+AA+D W + G + GA LV TA+++LLGV Sbjct 362 GVVAKLRAAIANDLDTPAALAAVDEWAE--ADRGTDEDGAADLVRTALNSLLGV 413 >gi|311739444|ref|ZP_07713279.1| cysteine--tRNA ligase [Corynebacterium pseudogenitalium ATCC 33035] gi|311305260|gb|EFQ81328.1| cysteine--tRNA ligase [Corynebacterium pseudogenitalium ATCC 33035] Length=415 Score = 484 bits (1246), Expect = 1e-134, Method: Compositional matrix adjust. Identities = 244/414 (59%), Positives = 298/414 (72%), Gaps = 6/414 (1%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPV-APGSKATMYVCGITPYDATHLGHAATY 59 M SW P +PG QLRLYDSA++ + PV G ATMYVCGITPYD+THLGHAATY Sbjct 4 MHSWPTPSFRPVPGDAAQLRLYDSANQTIAPVEVAGDTATMYVCGITPYDSTHLGHAATY 63 Query 60 VTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALR 119 +TFDLI+R +LD G ++HYVQNITD+DDPLFERA+RDGVDWR+L +++ LF DM L Sbjct 64 LTFDLIYRAFLDAGKKVHYVQNITDVDDPLFERAERDGVDWRELGTSQIDLFRSDMELLS 123 Query 120 VLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYD 179 V PPQDY+GA EA+ E+VE+++K+L GAAYV+D E+ DIY +AT +FGYES Y Sbjct 124 VFPPQDYIGAMEAVDEVVEMVQKLLDAGAAYVVDDP--EHPDIYASIEATERFGYESNYS 181 Query 180 RDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALS 239 + M ERGGDP RPGK + LDAL+WRA R GEP+W SPFGPGRPGWH+EC+AIA + Sbjct 182 AEEMRTFFAERGGDPDRPGKKNPLDALIWRAHREGEPAWDSPFGPGRPGWHIECSAIATN 241 Query 240 RIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNL 299 R+GS DIQGGGSDL FPHHEF+AAHAE R A+ YVH GMIG DG KMSKS GNL Sbjct 242 RLGSTFDIQGGGSDLKFPHHEFSAAHAEAALNVERMAQFYVHTGMIGLDGVKMSKSLGNL 301 Query 300 VLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVD 359 V V L +PSA+RLG+ AGHYR +R WS + LD A RL WR A A P A + Sbjct 302 VFVHKLVGAGEDPSAIRLGVFAGHYRDERDWSDEALDAAKRRLAAWREALAQPGSMAGAE 361 Query 360 -VVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGV 412 VVA++R +A+DLDTP A+AA+D W + G + GA LV TA+++LLGV Sbjct 362 GVVAKLRAAIANDLDTPAALAAVDEWAE--ADRGTDEDGAADLVRTALNSLLGV 413 >gi|306836112|ref|ZP_07469098.1| cysteine--tRNA ligase [Corynebacterium accolens ATCC 49726] gi|304567962|gb|EFM43541.1| cysteine--tRNA ligase [Corynebacterium accolens ATCC 49726] Length=412 Score = 482 bits (1241), Expect = 5e-134, Method: Compositional matrix adjust. Identities = 242/414 (59%), Positives = 299/414 (73%), Gaps = 6/414 (1%) Query 1 MQSWYCPPVPVLPGRGPQLRLYDSADRQVRPV-APGSKATMYVCGITPYDATHLGHAATY 59 M SW P +PG QL LYDSA++ PV G ATMYVCGITPYD+THLGHAATY Sbjct 1 MHSWPTPSYSRVPGDAAQLYLYDSANQTKAPVQVKGDTATMYVCGITPYDSTHLGHAATY 60 Query 60 VTFDLIHRLWLDLGHELHYVQNITDIDDPLFERADRDGVDWRDLAQAEVALFCEDMAALR 119 +TFDLI+R +LD G +++Y QNITD+DDPLFERA+RDGVDWR+L +++ LF DM L Sbjct 61 LTFDLIYRQFLDAGKKVNYAQNITDVDDPLFERAERDGVDWRELGTSQIDLFRSDMELLS 120 Query 120 VLPPQDYVGATEAIAEMVELIEKMLACGAAYVIDREMGEYQDIYFRADATLQFGYESGYD 179 V+PPQ ++GA EA+ E+V++++K+L GAAYV+D EY D+Y DAT +FGYES Y Sbjct 121 VIPPQHFIGAMEAVDEIVDMVQKLLDNGAAYVVDDP--EYPDVYASIDATEEFGYESNYS 178 Query 180 RDTMLRLCEERGGDPRRPGKSDELDALLWRAARPGEPSWPSPFGPGRPGWHVECAAIALS 239 + M ERGGDP RPGK +DAL+WRA R GEP+W SPFGPGRPGWH+EC+AIA + Sbjct 179 MEQMREFFAERGGDPDRPGKKHPMDALIWRAHREGEPAWKSPFGPGRPGWHIECSAIATN 238 Query 240 RIGSGLDIQGGGSDLIFPHHEFTAAHAECVSGERRFARHYVHAGMIGWDGHKMSKSRGNL 299 +GS DIQGGGSDL FPHHEF+AAHAE G R A+ YVH GMIG DG KMSKS GNL Sbjct 239 YLGSTFDIQGGGSDLKFPHHEFSAAHAEAALGVDRMAQFYVHTGMIGLDGVKMSKSLGNL 298 Query 300 VLVSALRAQDVEPSAVRLGLLAGHYRADRFWSQQVLDEATARLHRWRTATALPAGPAAVD 359 V V L Q +PSA+RLG+ +GHYRA+R WS +VLD+A ARL WRTA P +A + Sbjct 299 VFVHKLVEQGEDPSAIRLGVFSGHYRAERDWSDEVLDQAKARLATWRTALEAPGSLSAAE 358 Query 360 -VVARVRRYLADDLDTPKAIAALDGWVTDAVEYGGHDAGAPKLVATAIDALLGV 412 VA +R+ LADDLDTP A+ A+D W + G + GA +LV TA+D+LLGV Sbjct 359 GAVAGLRQALADDLDTPTALRAIDDWA--GSDRGEDEEGAAQLVRTALDSLLGV 410 Lambda K H 0.322 0.138 0.442 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 831576415104 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40