BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2132

Length=76
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15841623|ref|NP_336660.1|  CopG family DNA-binding protein [My...   154    5e-36
gi|15609269|ref|NP_216648.1|  hypothetical protein Rv2132 [Mycoba...   154    6e-36
gi|289447758|ref|ZP_06437502.1|  CopG family DNA-binding protein ...   119    2e-25
gi|229822545|ref|YP_002884071.1|  CopG family DNA-binding protein...  81.6    4e-14
gi|297623634|ref|YP_003705068.1|  hypothetical protein Trad_1403 ...  47.0    0.001
gi|289745379|ref|ZP_06504757.1|  conserved hypothetical protein [...  47.0    0.001
gi|333991904|ref|YP_004524518.1|  CopG family transcriptional reg...  46.6    0.001
gi|15609241|ref|NP_216620.1|  hypothetical protein Rv2104c [Mycob...  45.8    0.002
gi|116624724|ref|YP_826880.1|  hypothetical protein Acid_5648 [Ca...  45.1    0.004
gi|240170676|ref|ZP_04749335.1|  CopG family DNA-binding protein ...  44.3    0.007
gi|333990438|ref|YP_004523052.1|  hypothetical protein JDM601_179...  42.4    0.023
gi|145221523|ref|YP_001132201.1|  CopG/DNA-binding domain-contain...  42.4    0.026
gi|88810688|ref|ZP_01125945.1|  hypothetical protein NB231_16448 ...  41.6    0.038
gi|320105316|ref|YP_004180906.1|  hypothetical protein AciPR4_007...  41.6    0.041
gi|322435686|ref|YP_004217898.1|  hypothetical protein AciX9_2073...  38.5    0.34 
gi|300780205|ref|ZP_07090061.1|  toxin-antitoxin system [Coryneba...  38.1    0.43 
gi|317967918|ref|ZP_07969308.1|  hypothetical protein SCB02_00122...  35.8    2.2  
gi|336177809|ref|YP_004583184.1|  CopG/DNA-binding domain-contain...  35.8    2.3  
gi|298529362|ref|ZP_07016765.1|  conserved hypothetical protein [...  35.4    3.1  
gi|89074857|ref|ZP_01161311.1|  AcrB/AcrD/AcrF family protein [Ph...  33.9    8.7  


>gi|15841623|ref|NP_336660.1| CopG family DNA-binding protein [Mycobacterium tuberculosis CDC1551]
 gi|308232042|ref|ZP_07663980.1| hypothetical protein TMAG_00318 [Mycobacterium tuberculosis SUMu001]
 gi|308372148|ref|ZP_07667308.1| hypothetical protein TMDG_00609 [Mycobacterium tuberculosis SUMu004]
 11 more sequence titles
 Length=82

 Score =  154 bits (388),  Expect = 5e-36, Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%), Gaps = 0/76 (0%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGIDY  60
           MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGIDY
Sbjct  7   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGIDY  66

Query  61  SNIGDAIETLDGPASG  76
           SNIGDAIETLDGPASG
Sbjct  67  SNIGDAIETLDGPASG  82


>gi|15609269|ref|NP_216648.1| hypothetical protein Rv2132 [Mycobacterium tuberculosis H37Rv]
 gi|31793312|ref|NP_855805.1| hypothetical protein Mb2156 [Mycobacterium bovis AF2122/97]
 gi|121638014|ref|YP_978238.1| hypothetical protein BCG_2149 [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 58 more sequence titles
 Length=76

 Score =  154 bits (388),  Expect = 6e-36, Method: Compositional matrix adjust.
 Identities = 76/76 (100%), Positives = 76/76 (100%), Gaps = 0/76 (0%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGIDY  60
           MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGIDY
Sbjct  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGIDY  60

Query  61  SNIGDAIETLDGPASG  76
           SNIGDAIETLDGPASG
Sbjct  61  SNIGDAIETLDGPASG  76


>gi|289447758|ref|ZP_06437502.1| CopG family DNA-binding protein [Mycobacterium tuberculosis CPHL_A]
 gi|289420716|gb|EFD17917.1| CopG family DNA-binding protein [Mycobacterium tuberculosis CPHL_A]
Length=59

 Score =  119 bits (297),  Expect = 2e-25, Method: Compositional matrix adjust.
 Identities = 59/59 (100%), Positives = 59/59 (100%), Gaps = 0/59 (0%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGID  59
           MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGID
Sbjct  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGID  59


>gi|229822545|ref|YP_002884071.1| CopG family DNA-binding protein [Beutenbergia cavernae DSM 12333]
 gi|229568458|gb|ACQ82309.1| CopG family DNA-binding protein [Beutenbergia cavernae DSM 12333]
Length=80

 Score = 81.6 bits (200),  Expect = 4e-14, Method: Compositional matrix adjust.
 Identities = 43/72 (60%), Positives = 54/72 (75%), Gaps = 1/72 (1%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVAN-RFQQQTYDMGEGID  59
           MRTT+ L DDVAAA +RLR+ER IGL EAVNEL RAGL +   A  R++Q+T D+G  ID
Sbjct  1   MRTTIRLDDDVAAAAERLRRERHIGLGEAVNELARAGLHRGAPAERRYRQRTADLGLRID  60

Query  60  YSNIGDAIETLD  71
            SN+ +A+E LD
Sbjct  61  VSNVAEALELLD  72


>gi|297623634|ref|YP_003705068.1| hypothetical protein Trad_1403 [Truepera radiovictrix DSM 17093]
 gi|297164814|gb|ADI14525.1| conserved hypothetical protein [Truepera radiovictrix DSM 17093]
Length=80

 Score = 47.0 bits (110),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 27/80 (34%), Positives = 44/80 (55%), Gaps = 4/80 (5%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLT---KRQVANRFQQQTYDMGEG  57
           MRTT++L DDV   ++RL+KER       VN  +R GL    + +  + F+ QT  +G  
Sbjct  1   MRTTLTLDDDVEKRLRRLQKERGESFKSLVNRALREGLVALEQPRATDAFRTQTVSLGRA  60

Query  58  -IDYSNIGDAIETLDGPASG  76
            ++  ++ DA+E  +G   G
Sbjct  61  LVNLDSVADALEVAEGAHHG  80


>gi|289745379|ref|ZP_06504757.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289685907|gb|EFD53395.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
Length=84

 Score = 47.0 bits (110),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 24/55 (44%), Positives = 33/55 (60%), Gaps = 0/55 (0%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMG  55
           MRTTVSL DDV   V+R   ER +   +A+N+ IR G + R   + F  +T D+G
Sbjct  1   MRTTVSLDDDVEQLVRRRMAERQVSFKKALNDAIRDGASGRPAPSHFSTRTADLG  55


>gi|333991904|ref|YP_004524518.1| CopG family transcriptional regulator [Mycobacterium sp. JDM601]
 gi|333487872|gb|AEF37264.1| CopG family DNA-binding protein [Mycobacterium sp. JDM601]
Length=75

 Score = 46.6 bits (109),  Expect = 0.001, Method: Compositional matrix adjust.
 Identities = 28/65 (44%), Positives = 41/65 (64%), Gaps = 3/65 (4%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVA--NRFQQQTYDMGEGI  58
           MRTTV +  DVAA V RLR +  +G+SEA+N L R G+  +  A   R++ +T  +G  +
Sbjct  1   MRTTVVIDSDVAAEVTRLRGQ-GMGVSEALNLLARRGMAAQTSAPGTRYRHRTAHIGLKV  59

Query  59  DYSNI  63
           D SN+
Sbjct  60  DVSNV  64


>gi|15609241|ref|NP_216620.1| hypothetical protein Rv2104c [Mycobacterium tuberculosis H37Rv]
 gi|15841595|ref|NP_336632.1| hypothetical protein MT2164 [Mycobacterium tuberculosis CDC1551]
 gi|31793286|ref|NP_855779.1| hypothetical protein Mb2130c [Mycobacterium bovis AF2122/97]
 73 more sequence titles
 Length=84

 Score = 45.8 bits (107),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 23/55 (42%), Positives = 33/55 (60%), Gaps = 0/55 (0%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMG  55
           MRTTV+L DDV   V+R   ER +   +A+N+ IR G + R   + F  +T D+G
Sbjct  1   MRTTVTLDDDVEQLVRRRMAERQVSFKKALNDAIRDGASGRPAPSHFSTRTADLG  55


>gi|116624724|ref|YP_826880.1| hypothetical protein Acid_5648 [Candidatus Solibacter usitatus 
Ellin6076]
 gi|116227886|gb|ABJ86595.1| conserved hypothetical protein [Candidatus Solibacter usitatus 
Ellin6076]
Length=87

 Score = 45.1 bits (105),  Expect = 0.004, Method: Compositional matrix adjust.
 Identities = 28/75 (38%), Positives = 41/75 (55%), Gaps = 7/75 (9%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTK--RQVANRFQQQTYDMGEGI  58
           MRTTV+L  DV  A++   + R +   +A+N+ IR GL K   +   RF Q+TY +G   
Sbjct  1   MRTTVTLDPDVERALKATMRTRGVSFKQALNDAIRTGLLKPGSKTRRRFVQKTYSLGAEQ  60

Query  59  DYS-----NIGDAIE  68
           ++       I DAIE
Sbjct  61  NFRWEKALAIADAIE  75


>gi|240170676|ref|ZP_04749335.1| CopG family DNA-binding protein [Mycobacterium kansasii ATCC 
12478]
Length=91

 Score = 44.3 bits (103),  Expect = 0.007, Method: Compositional matrix adjust.
 Identities = 25/65 (39%), Positives = 41/65 (64%), Gaps = 3/65 (4%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANR--FQQQTYDMGEGI  58
           +RTTV +  DVA  ++RLR+E  +GLSEA+N L R G+T+        ++ +T  +G  +
Sbjct  17  VRTTVVIDSDVAGEIERLRRE-GMGLSEALNLLARRGMTRGAPPKSVVYKHRTSRIGLKV  75

Query  59  DYSNI  63
           D +N+
Sbjct  76  DVTNV  80


>gi|333990438|ref|YP_004523052.1| hypothetical protein JDM601_1798 [Mycobacterium sp. JDM601]
 gi|333486406|gb|AEF35798.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=83

 Score = 42.4 bits (98),  Expect = 0.023, Method: Compositional matrix adjust.
 Identities = 24/55 (44%), Positives = 32/55 (59%), Gaps = 1/55 (1%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMG  55
           MRTTV+L DDV   ++R   ER +   +A+NE IR G   R     FQ +T D+G
Sbjct  1   MRTTVTLDDDVEQLIRRRMAERQLSFKQALNEAIRDGSAGRATPQ-FQTRTADLG  54


>gi|145221523|ref|YP_001132201.1| CopG/DNA-binding domain-containing protein [Mycobacterium gilvum 
PYR-GCK]
 gi|145214009|gb|ABP43413.1| CopG domain protein DNA-binding domain protein [Mycobacterium 
gilvum PYR-GCK]
Length=84

 Score = 42.4 bits (98),  Expect = 0.026, Method: Compositional matrix adjust.
 Identities = 22/55 (40%), Positives = 30/55 (55%), Gaps = 0/55 (0%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMG  55
           MRTTV+L DD  A ++R   E+ I   EA+N  IR G  +R     F  +  D+G
Sbjct  1   MRTTVTLDDDTVALIRRRMAEQGISFKEALNNAIRDGAAQRPAPAAFSTRVADLG  55


>gi|88810688|ref|ZP_01125945.1| hypothetical protein NB231_16448 [Nitrococcus mobilis Nb-231]
 gi|88792318|gb|EAR23428.1| hypothetical protein NB231_16448 [Nitrococcus mobilis Nb-231]
Length=92

 Score = 41.6 bits (96),  Expect = 0.038, Method: Compositional matrix adjust.
 Identities = 26/76 (35%), Positives = 40/76 (53%), Gaps = 5/76 (6%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANR---FQQQTYDMG--  55
           MRTTV+L  DVAA ++ L   R     E +N+++R GLT +  A R   F  + +  G  
Sbjct  5   MRTTVTLEPDVAAKLKELAHRRRASFKETLNDVLRKGLTSQAKAGRSEPFVVKPHSGGFR  64

Query  56  EGIDYSNIGDAIETLD  71
            GID   +   ++ L+
Sbjct  65  PGIDPDKLNQLLDQLE  80


>gi|320105316|ref|YP_004180906.1| hypothetical protein AciPR4_0071 [Terriglobus saanensis SP1PR4]
 gi|319923837|gb|ADV80912.1| hypothetical protein AciPR4_0071 [Terriglobus saanensis SP1PR4]
Length=80

 Score = 41.6 bits (96),  Expect = 0.041, Method: Compositional matrix adjust.
 Identities = 23/75 (31%), Positives = 43/75 (58%), Gaps = 4/75 (5%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKR--QVANRFQQQTYDMG--E  56
           MRTT+++ DDVAA ++R  +     + +A+N  +R  L  +  + A +F+ Q+  +G   
Sbjct  1   MRTTLTIDDDVAALLKREMRRSGEPMKQAINRCLRTALAVKSTEPAPKFKVQSRKLGLLP  60

Query  57  GIDYSNIGDAIETLD  71
           G+ Y N+   ++ LD
Sbjct  61  GMSYDNLEAVLDQLD  75


>gi|322435686|ref|YP_004217898.1| hypothetical protein AciX9_2073 [Acidobacterium sp. MP5ACTX9]
 gi|321163413|gb|ADW69118.1| hypothetical protein AciX9_2073 [Acidobacterium sp. MP5ACTX9]
Length=81

 Score = 38.5 bits (88),  Expect = 0.34, Method: Compositional matrix adjust.
 Identities = 21/65 (33%), Positives = 38/65 (59%), Gaps = 3/65 (4%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANR---FQQQTYDMGEG  57
           MRTT+++ DDVAA +Q+  +     L +AVN L+RAGL +     +   F+ + +D    
Sbjct  1   MRTTLTIDDDVAALLQKELRRSGEPLKQAVNRLLRAGLYQAATPMKSKPFKVRPFDASLP  60

Query  58  IDYSN  62
            ++++
Sbjct  61  TEWTS  65


>gi|300780205|ref|ZP_07090061.1| toxin-antitoxin system [Corynebacterium genitalium ATCC 33030]
 gi|300534315|gb|EFK55374.1| toxin-antitoxin system [Corynebacterium genitalium ATCC 33030]
Length=80

 Score = 38.1 bits (87),  Expect = 0.43, Method: Compositional matrix adjust.
 Identities = 21/71 (30%), Positives = 38/71 (54%), Gaps = 0/71 (0%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGIDY  60
           MR T+ L ++V  A + +  E+   + EAVN+L RAGL +R  A  +   +  MG  ++ 
Sbjct  1   MRLTIRLDEEVYTAARAIAAEKGTSVGEAVNDLARAGLPRRDSAVDYIPMSQPMGMKVEC  60

Query  61  SNIGDAIETLD  71
             + + ++  D
Sbjct  61  IKVSEILDLED  71


>gi|317967918|ref|ZP_07969308.1| hypothetical protein SCB02_00122 [Synechococcus sp. CB0205]
Length=86

 Score = 35.8 bits (81),  Expect = 2.2, Method: Compositional matrix adjust.
 Identities = 21/46 (46%), Positives = 29/46 (64%), Gaps = 3/46 (6%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANR  46
           MRTT+SL DDV AA + L ++R   +   ++EL R GL +   ANR
Sbjct  8   MRTTLSLDDDVLAAAKVLARQRKQPIGSVISELARQGLAQ---ANR  50


>gi|336177809|ref|YP_004583184.1| CopG/DNA-binding domain-containing protein [Frankia symbiont 
of Datisca glomerata]
 gi|334858789|gb|AEH09263.1| CopG/DNA-binding domain-containing protein [Frankia symbiont 
of Datisca glomerata]
Length=82

 Score = 35.8 bits (81),  Expect = 2.3, Method: Compositional matrix adjust.
 Identities = 17/38 (45%), Positives = 27/38 (72%), Gaps = 0/38 (0%)

Query  5   VSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQ  42
           ++L  DVAAA+Q+  +E+ +   EA+N L+RAGL  R+
Sbjct  1   MTLDPDVAAALQKEVREQGMSFEEALNTLVRAGLANRR  38


>gi|298529362|ref|ZP_07016765.1| conserved hypothetical protein [Desulfonatronospira thiodismutans 
ASO3-1]
 gi|298510798|gb|EFI34701.1| conserved hypothetical protein [Desulfonatronospira thiodismutans 
ASO3-1]
Length=81

 Score = 35.4 bits (80),  Expect = 3.1, Method: Compositional matrix adjust.
 Identities = 26/79 (33%), Positives = 40/79 (51%), Gaps = 9/79 (11%)

Query  1   MRTTVSLADDVAAAVQRLRKERSIGLSEAVNELIRAGLTKRQVANRFQQQTY-----DMG  55
           MRTT+++ +DV    + L   R I     +NE +RAGL  R+V     QQ Y      MG
Sbjct  1   MRTTLAIDNDVLEKARALAARRKIPFKTVINEALRAGL--REVEKPALQQDYTTMPQPMG  58

Query  56  --EGIDYSNIGDAIETLDG  72
             +G +  NI + +  ++G
Sbjct  59  LKQGRNLDNIQELLAQVEG  77


>gi|89074857|ref|ZP_01161311.1| AcrB/AcrD/AcrF family protein [Photobacterium sp. SKA34]
 gi|89049432|gb|EAR54994.1| AcrB/AcrD/AcrF family protein [Photobacterium sp. SKA34]
Length=1040

 Score = 33.9 bits (76),  Expect = 8.7, Method: Compositional matrix adjust.
 Identities = 22/52 (43%), Positives = 31/52 (60%), Gaps = 2/52 (3%)

Query  21   ERSIGLSEAVNELIRAGLTKRQVANRFQQQTYDMGEGIDYSNIGDAIETLDG  72
            E +IG+SE  N L + GLT  QVAN  QQ++ D+  GI  +  GD +   +G
Sbjct  182  EIAIGVSE--NALRKYGLTFEQVANVVQQRSIDLPGGIIKAKDGDLLVRTNG  231



Lambda     K      H
   0.314    0.130    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 130617491818


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40