BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2152c Length=494 Score E Sequences producing significant alignments: (Bits) Value gi|15609289|ref|NP_216668.1| UDP-N-acetylmuramate--L-alanine lig... 978 0.0 gi|289443657|ref|ZP_06433401.1| UDP-N-acetylMuramate-alanine lig... 976 0.0 gi|340627160|ref|YP_004745612.1| putative UDP-N-acetylmuramate-a... 976 0.0 gi|289447780|ref|ZP_06437524.1| UDP-N-acetylmuramate-alanine lig... 975 0.0 gi|298525647|ref|ZP_07013056.1| UDP-N-acetylmuramate-alanine lig... 975 0.0 gi|289570268|ref|ZP_06450495.1| UDP-N-acetylmuramate-alanine lig... 952 0.0 gi|289554061|ref|ZP_06443271.1| UDP-N-acetylmuramate-alanine lig... 871 0.0 gi|289762314|ref|ZP_06521692.1| UDP-N-acetylmuramate-alanine lig... 863 0.0 gi|289574835|ref|ZP_06455062.1| LOW QUALITY PROTEIN: cell divisi... 818 0.0 gi|254821552|ref|ZP_05226553.1| UDP-N-acetylmuramate--L-alanine ... 780 0.0 gi|342859868|ref|ZP_08716521.1| UDP-N-acetylmuramate--L-alanine ... 778 0.0 gi|336461942|gb|EGO40794.1| UDP-N-acetylmuramate--alanine ligase... 777 0.0 gi|41407994|ref|NP_960830.1| UDP-N-acetylmuramate--L-alanine lig... 776 0.0 gi|296166019|ref|ZP_06848471.1| UDP-N-acetylmuramate--L-alanine ... 759 0.0 gi|240168216|ref|ZP_04746875.1| UDP-N-acetylmuramate--L-alanine ... 755 0.0 gi|118463520|ref|YP_881541.1| UDP-N-acetylmuramate--L-alanine li... 755 0.0 gi|254775010|ref|ZP_05216526.1| UDP-N-acetylmuramate--L-alanine ... 752 0.0 gi|183983182|ref|YP_001851473.1| UDP-N-acetylmuramate-alanine li... 731 0.0 gi|118618794|ref|YP_907126.1| UDP-N-acetylmuramate--L-alanine li... 723 0.0 gi|15827435|ref|NP_301698.1| UDP-N-acetylmuramate--L-alanine lig... 710 0.0 gi|108800221|ref|YP_640418.1| UDP-N-acetylmuramate--L-alanine li... 702 0.0 gi|118469061|ref|YP_888503.1| UDP-N-acetylmuramate--L-alanine li... 702 0.0 gi|333990384|ref|YP_004522998.1| UDP-N-acetylmuramate-alanine li... 699 0.0 gi|315443923|ref|YP_004076802.1| UDP-N-acetylmuramate--L-alanine... 646 0.0 gi|145223576|ref|YP_001134254.1| UDP-N-acetylmuramate--L-alanine... 642 0.0 gi|169629094|ref|YP_001702743.1| UDP-N-acetylmuramate--L-alanine... 635 4e-180 gi|120404494|ref|YP_954323.1| UDP-N-acetylmuramate--L-alanine li... 634 1e-179 gi|312140141|ref|YP_004007477.1| UDP-N-acetylmuramate-l-alanine ... 607 1e-171 gi|111018100|ref|YP_701072.1| UDP-N-acetylmuramate--L-alanine li... 591 7e-167 gi|54023735|ref|YP_117977.1| UDP-N-acetylmuramate--L-alanine lig... 589 4e-166 gi|226307038|ref|YP_002766998.1| UDP-N-acetylmuramate--L-alanine... 588 5e-166 gi|226360229|ref|YP_002778007.1| UDP-N-acetylmuramate--L-alanine... 588 7e-166 gi|333918999|ref|YP_004492580.1| UDP-N-acetylmuramate--L-alanine... 586 3e-165 gi|296140341|ref|YP_003647584.1| UDP-N-acetylmuramate/alanine li... 578 7e-163 gi|229490346|ref|ZP_04384187.1| UDP-N-acetylmuramate--alanine li... 572 4e-161 gi|262202909|ref|YP_003274117.1| UDP-N-acetylmuramate/alanine li... 553 3e-155 gi|296394963|ref|YP_003659847.1| UDP-N-acetylmuramate/alanine li... 545 6e-153 gi|326382560|ref|ZP_08204251.1| UDP-N-acetylmuramate--L-alanine ... 540 2e-151 gi|343924211|ref|ZP_08763774.1| UDP-N-acetylmuramate--L-alanine ... 515 8e-144 gi|334697230|gb|AEG82027.1| UDP-N-acetylmuramate--alanine ligase... 490 2e-136 gi|337291119|ref|YP_004630140.1| UDP-N-acetylmuramate--alanine l... 489 5e-136 gi|302206518|gb|ADL10860.1| UDP-N-acetyl muramate--L-alanine lig... 483 3e-134 gi|344044827|gb|EGV40502.1| UDP-N-acetylmuramate--L-alanine liga... 483 3e-134 gi|172040884|ref|YP_001800598.1| UDP-N-acetylmuramate--L-alanine... 482 5e-134 gi|256379761|ref|YP_003103421.1| UDP-N-acetylmuramate--L-alanine... 482 5e-134 gi|145296119|ref|YP_001138940.1| UDP-N-acetylmuramate--L-alanine... 482 6e-134 gi|300858813|ref|YP_003783796.1| UDP-N-acetylmuramate--alanine l... 482 8e-134 gi|29337227|sp|P94335.5|MURC_CORGL RecName: Full=UDP-N-acetylmur... 481 9e-134 gi|300788096|ref|YP_003768387.1| UDP-N-acetylmuramate--alanine l... 480 2e-133 gi|19553357|ref|NP_601359.1| UDP-N-acetylmuramate--L-alanine lig... 480 2e-133 >gi|15609289|ref|NP_216668.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium tuberculosis H37Rv] gi|15841644|ref|NP_336681.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium tuberculosis CDC1551] gi|31793332|ref|NP_855825.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium bovis AF2122/97] 65 more sequence titles Length=494 Score = 978 bits (2528), Expect = 0.0, Method: Compositional matrix adjust. Identities = 493/494 (99%), Positives = 494/494 (100%), Gaps = 0/494 (0%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 +STEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI Sbjct 1 MSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV Sbjct 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ Sbjct 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE Sbjct 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 Query 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL Sbjct 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 Query 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS Sbjct 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL Sbjct 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV Sbjct 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 Query 481 RANRSAPGRPGVLG 494 RANRSAPGRPGVLG Sbjct 481 RANRSAPGRPGVLG 494 >gi|289443657|ref|ZP_06433401.1| UDP-N-acetylMuramate-alanine ligase [Mycobacterium tuberculosis T46] gi|289416576|gb|EFD13816.1| UDP-N-acetylMuramate-alanine ligase [Mycobacterium tuberculosis T46] Length=494 Score = 976 bits (2522), Expect = 0.0, Method: Compositional matrix adjust. Identities = 492/494 (99%), Positives = 494/494 (100%), Gaps = 0/494 (0%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 +STEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI Sbjct 1 MSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGGATAVVTT+AAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV Sbjct 61 GHDASSLDLLPGGATAVVTTYAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ Sbjct 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE Sbjct 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 Query 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL Sbjct 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 Query 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS Sbjct 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL Sbjct 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV Sbjct 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 Query 481 RANRSAPGRPGVLG 494 RANRSAPGRPGVLG Sbjct 481 RANRSAPGRPGVLG 494 >gi|340627160|ref|YP_004745612.1| putative UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium canettii CIPT 140010059] gi|340005350|emb|CCC44508.1| putative UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium canettii CIPT 140010059] Length=494 Score = 976 bits (2522), Expect = 0.0, Method: Compositional matrix adjust. Identities = 492/494 (99%), Positives = 493/494 (99%), Gaps = 0/494 (0%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 +STEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI Sbjct 1 MSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV Sbjct 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ Sbjct 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE Sbjct 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 Query 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL Sbjct 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 Query 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS Sbjct 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 ATLAAARMVLEQ DGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL Sbjct 361 ATLAAARMVLEQDDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV Sbjct 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 Query 481 RANRSAPGRPGVLG 494 RANRSAPGRPGVLG Sbjct 481 RANRSAPGRPGVLG 494 >gi|289447780|ref|ZP_06437524.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium tuberculosis CPHL_A] gi|289420738|gb|EFD17939.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium tuberculosis CPHL_A] Length=494 Score = 975 bits (2520), Expect = 0.0, Method: Compositional matrix adjust. Identities = 492/494 (99%), Positives = 493/494 (99%), Gaps = 0/494 (0%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 +STEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI Sbjct 1 MSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV Sbjct 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ Sbjct 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIV GGALVVCTDDPGGAALAQRATE Sbjct 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVSGGALVVCTDDPGGAALAQRATE 240 Query 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL Sbjct 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 Query 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS Sbjct 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL Sbjct 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV Sbjct 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 Query 481 RANRSAPGRPGVLG 494 RANRSAPGRPGVLG Sbjct 481 RANRSAPGRPGVLG 494 >gi|298525647|ref|ZP_07013056.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium tuberculosis 94_M4241A] gi|298495441|gb|EFI30735.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium tuberculosis 94_M4241A] Length=494 Score = 975 bits (2520), Expect = 0.0, Method: Compositional matrix adjust. Identities = 492/494 (99%), Positives = 493/494 (99%), Gaps = 0/494 (0%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 +STEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI Sbjct 1 MSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLR AVLAKLMAGRTTLMV Sbjct 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRSAVLAKLMAGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ Sbjct 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE Sbjct 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 Query 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL Sbjct 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 Query 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS Sbjct 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL Sbjct 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV Sbjct 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 Query 481 RANRSAPGRPGVLG 494 RANRSAPGRPGVLG Sbjct 481 RANRSAPGRPGVLG 494 >gi|289570268|ref|ZP_06450495.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium tuberculosis T17] gi|289544022|gb|EFD47670.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium tuberculosis T17] Length=482 Score = 952 bits (2461), Expect = 0.0, Method: Compositional matrix adjust. Identities = 481/482 (99%), Positives = 482/482 (100%), Gaps = 0/482 (0%) Query 13 VHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLDLLPG 72 +HMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLDLLPG Sbjct 1 MHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLDLLPG 60 Query 73 GATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTTTTSM 132 GATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTTTTSM Sbjct 61 GATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTTTTSM 120 Query 133 LIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVITNIE 192 LIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVITNIE Sbjct 121 LIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVITNIE 180 Query 193 SDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRYGSVP 252 SDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRYGSVP Sbjct 181 SDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRYGSVP 240 Query 253 GETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALGALLAAVQI 312 GETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALGALLAAVQI Sbjct 241 GETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALGALLAAVQI 300 Query 313 GAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLAAARMVLEQ 372 GAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLAAARMVLEQ Sbjct 301 GAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLAAARMVLEQ 360 Query 373 GDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVSGASVAEHV 432 GDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVSGASVAEHV Sbjct 361 GDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVSGASVAEHV 420 Query 433 TVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRANRSAPGRPGV 492 TVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRANRSAPGRPGV Sbjct 421 TVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRANRSAPGRPGV 480 Query 493 LG 494 LG Sbjct 481 LG 482 >gi|289554061|ref|ZP_06443271.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium tuberculosis KZN 605] gi|289438693|gb|EFD21186.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium tuberculosis KZN 605] Length=438 Score = 871 bits (2250), Expect = 0.0, Method: Compositional matrix adjust. Identities = 437/438 (99%), Positives = 438/438 (100%), Gaps = 0/438 (0%) Query 57 LIRIGHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRT 116 +IRIGHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRT Sbjct 1 MIRIGHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRT 60 Query 117 TLMVTGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDG 176 TLMVTGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDG Sbjct 61 TLMVTGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDG 120 Query 177 SLLQYTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQ 236 SLLQYTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQ Sbjct 121 SLLQYTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQ 180 Query 237 RATELGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGR 296 RATELGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGR Sbjct 181 RATELGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGR 240 Query 297 HMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHP 356 HMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHP Sbjct 241 HMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHP 300 Query 357 TEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAR 416 TEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAR Sbjct 301 TEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAR 360 Query 417 EQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILT 476 EQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILT Sbjct 361 EQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILT 420 Query 477 ALRVRANRSAPGRPGVLG 494 ALRVRANRSAPGRPGVLG Sbjct 421 ALRVRANRSAPGRPGVLG 438 >gi|289762314|ref|ZP_06521692.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium tuberculosis GM 1503] gi|289709820|gb|EFD73836.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium tuberculosis GM 1503] Length=495 Score = 863 bits (2229), Expect = 0.0, Method: Compositional matrix adjust. Identities = 477/497 (96%), Positives = 480/497 (97%), Gaps = 5/497 (1%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 +STEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI Sbjct 1 MSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRG---IPVVLRPAVLAKLMAGRTT 117 GHDAS LDLLPGGAT VVTTHAAIPKT P + R+RG P VLAKLMAGRTT Sbjct 61 GHDASPLDLLPGGATGVVTTHAAIPKTKPRV--RRKRGAAAFPWCCGRPVLAKLMAGRTT 118 Query 118 LMVTGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGS 177 LMVTGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGS Sbjct 119 LMVTGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGS 178 Query 178 LLQYTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQR 237 LLQYTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQR Sbjct 179 LLQYTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQR 238 Query 238 ATELGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRH 297 ATELGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRH Sbjct 239 ATELGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRH 298 Query 298 MALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPT 357 MALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPT Sbjct 299 MALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPT 358 Query 358 EISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGARE 417 EISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGARE Sbjct 359 EISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGARE 418 Query 418 QPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTA 477 QPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTA Sbjct 419 QPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTA 478 Query 478 LRVRANRSAPGRPGVLG 494 LRVRANRSAPGRPGVLG Sbjct 479 LRVRANRSAPGRPGVLG 495 >gi|289574835|ref|ZP_06455062.1| LOW QUALITY PROTEIN: cell division protein ftsQ [Mycobacterium tuberculosis K85] gi|289539266|gb|EFD43844.1| LOW QUALITY PROTEIN: cell division protein ftsQ [Mycobacterium tuberculosis K85] Length=437 Score = 818 bits (2114), Expect = 0.0, Method: Compositional matrix adjust. Identities = 410/410 (100%), Positives = 410/410 (100%), Gaps = 0/410 (0%) Query 85 PKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTTTTSMLIVALQHCGLDP 144 PKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTTTTSMLIVALQHCGLDP Sbjct 28 PKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTTTTSMLIVALQHCGLDP 87 Query 145 SFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVITNIESDHLDFYGSVEA 204 SFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVITNIESDHLDFYGSVEA Sbjct 88 SFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVITNIESDHLDFYGSVEA 147 Query 205 YVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRYGSVPGETMAATLVSWQ 264 YVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRYGSVPGETMAATLVSWQ Sbjct 148 YVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRYGSVPGETMAATLVSWQ 207 Query 265 QQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALGALLAAVQIGAPADEVLDGLA 324 QQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALGALLAAVQIGAPADEVLDGLA Sbjct 208 QQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALGALLAAVQIGAPADEVLDGLA 267 Query 325 GFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLAAARMVLEQGDGGRCMVVFQP 384 GFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLAAARMVLEQGDGGRCMVVFQP Sbjct 268 GFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLAAARMVLEQGDGGRCMVVFQP 327 Query 385 HLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSA 444 HLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSA Sbjct 328 HLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSA 387 Query 445 VAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRANRSAPGRPGVLG 494 VAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRANRSAPGRPGVLG Sbjct 388 VAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRANRSAPGRPGVLG 437 >gi|254821552|ref|ZP_05226553.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium intracellulare ATCC 13950] Length=492 Score = 780 bits (2014), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/491 (84%), Positives = 446/491 (91%), Gaps = 4/491 (0%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++TEQLPP+L+RVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRG+HALRARGA I I Sbjct 1 MTTEQLPPELQRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGIHALRARGAQINI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGGATAV+TTHAAIPKTNPELVEARRRGIPV+LRPAVLAKLM GRTTLMV Sbjct 61 GHDASSLDLLPGGATAVITTHAAIPKTNPELVEARRRGIPVILRPAVLAKLMDGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCG DPSFAVGGE+GEAGTNAHHGSGDCFVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMLIVALQHCGRDPSFAVGGEMGEAGTNAHHGSGDCFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTP+VAV+TNIE+DHLDFYGS AYV VFD+FV+R+ PGGALVVC DDPG AALA+R E Sbjct 181 YTPNVAVVTNIETDHLDFYGSAGAYVDVFDAFVDRLAPGGALVVCVDDPGAAALARRTAE 240 Query 241 LGIRVLRYG---SVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRH 297 LGIRVLRYG S+PGE +AATL+SWQQQG AVA I+LA +L Q PRVMRLSVPGRH Sbjct 241 LGIRVLRYGSGASLPGEPLAATLLSWQQQGTEAVAQIQLAPDLDPEQRPRVMRLSVPGRH 300 Query 298 MALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPT 357 MALNA+GALLAA++IGAP D VLDGLAGFEGVRRRFELVGT G G+ VRVFDDYAHHPT Sbjct 301 MALNAMGALLAALEIGAPVDAVLDGLAGFEGVRRRFELVGTAGNGQ-PVRVFDDYAHHPT 359 Query 358 EISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGARE 417 EI ATLAA R +LEQ GR + VFQPHLYSRTKAFA EFG AL+AADEVFVLDVYGARE Sbjct 360 EIVATLAAVRTLLEQSGDGRSIAVFQPHLYSRTKAFAEEFGHALDAADEVFVLDVYGARE 419 Query 418 QPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTA 477 QPLAGVSGASVAEHV+VP+RY+P+FSA A+QVAA A PGDVIVTMGAGDVTLLGPEI+TA Sbjct 420 QPLAGVSGASVAEHVSVPVRYLPNFSAAAEQVAAVAGPGDVIVTMGAGDVTLLGPEIVTA 479 Query 478 LRVRANRSAPG 488 LR RANR APG Sbjct 480 LRARANRGAPG 490 >gi|342859868|ref|ZP_08716521.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium colombiense CECT 3035] gi|342133000|gb|EGT86220.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium colombiense CECT 3035] Length=488 Score = 778 bits (2008), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/489 (85%), Positives = 446/489 (92%), Gaps = 5/489 (1%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++TEQLPP+L+RVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRG+HALRARGA I I Sbjct 1 MTTEQLPPELQRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGIHALRARGAQINI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDA+SLDLLPGGATAV+TTHAAIPKTNPELVEARRRGIPV+LRPAVLAKLM GRTTLMV Sbjct 61 GHDAASLDLLPGGATAVITTHAAIPKTNPELVEARRRGIPVILRPAVLAKLMNGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCG DPSFAVGGE+GEAGTNAHHGSGDCFVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMLIVALQHCGRDPSFAVGGEMGEAGTNAHHGSGDCFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTP+VAV+TNIE+DHLDFYGS +AYVAVFD+FVER+ PGGALVVC DDPG ALA+R E Sbjct 181 YTPNVAVVTNIETDHLDFYGSADAYVAVFDAFVERLAPGGALVVCVDDPGAEALARRTAE 240 Query 241 LGIRVLRYGSV-PGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMA 299 LGIRVLRYGS G+ +AATL+SW+QQG AVA IRLA EL AQ P VMRLSVPGRHMA Sbjct 241 LGIRVLRYGSPRSGDELAATLLSWEQQGTEAVAQIRLAPELDPAQHPLVMRLSVPGRHMA 300 Query 300 LNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEI 359 LNA+GALLAA++IGAP D VLDGLAGFEGVRRRFELVG+ ASVRVFDDYAHHPTEI Sbjct 301 LNAMGALLAALEIGAPIDAVLDGLAGFEGVRRRFELVGSA----ASVRVFDDYAHHPTEI 356 Query 360 SATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQP 419 ATLAA R +LEQ GR + VFQPHLYSRTKAFA EFG AL+AADEVFVLDVYGAREQP Sbjct 357 VATLAAVRTLLEQSGAGRSIAVFQPHLYSRTKAFAEEFGHALDAADEVFVLDVYGAREQP 416 Query 420 LAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALR 479 LAGVSGASVAEHV+VP+RY+P F+A A+QVAAAA PGDVIVTMGAGDVTLLGPEI+TALR Sbjct 417 LAGVSGASVAEHVSVPVRYLPHFAAAAEQVAAAAGPGDVIVTMGAGDVTLLGPEIVTALR 476 Query 480 VRANRSAPG 488 VRANRSAPG Sbjct 477 VRANRSAPG 485 >gi|336461942|gb|EGO40794.1| UDP-N-acetylmuramate--alanine ligase [Mycobacterium avium subsp. paratuberculosis S397] Length=496 Score = 777 bits (2006), Expect = 0.0, Method: Compositional matrix adjust. Identities = 415/496 (84%), Positives = 447/496 (91%), Gaps = 11/496 (2%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++T+QLP +L RVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRG+HALRARGA IRI Sbjct 1 MTTDQLPAELERVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGIHALRARGAQIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGG TAV+TTHAAIPKTNPELVEARRRGIPV+LRPAVLAKLM GRTTLMV Sbjct 61 GHDASSLDLLPGGPTAVITTHAAIPKTNPELVEARRRGIPVILRPAVLAKLMDGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCG DPSFAVGGE+GEAGTNAHHGSGDCFVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMLIVALQHCGRDPSFAVGGEMGEAGTNAHHGSGDCFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTP VAV+TNIE+DHLDFYGS +AYVAVFD+FVER+ PGGALVVC DDPG AALA+R E Sbjct 181 YTPDVAVVTNIETDHLDFYGSADAYVAVFDAFVERLAPGGALVVCVDDPGAAALARRTAE 240 Query 241 LGIRVLRYGS------VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVP 294 LGIRVLRYGS GE +AATLVSWQQQG AVA IRLA E Q P VMRLSVP Sbjct 241 LGIRVLRYGSGSHGQAPSGEPLAATLVSWQQQGTEAVAQIRLAGE---QQHPLVMRLSVP 297 Query 295 GRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCG--VGKASVRVFDDY 352 GRHMALNA+GALLAA++IGAP + VLDGLAGFEGVRRRFELVGT G ++VRVFDDY Sbjct 298 GRHMALNAMGALLAAIEIGAPTEAVLDGLAGFEGVRRRFELVGTAGGPAPSSTVRVFDDY 357 Query 353 AHHPTEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDV 412 AHHPTEI+ATLAA R +LEQ GGR + VFQPHLYSRTKAFA EFGRAL+AADEVFVLDV Sbjct 358 AHHPTEIAATLAAVRTLLEQSGGGRSIAVFQPHLYSRTKAFAEEFGRALDAADEVFVLDV 417 Query 413 YGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGP 472 YGAREQPLAGVSGASVAEHV+VP+RY+PDFSA A+QVAAAA+PGDVIVTMGAGDVTLLGP Sbjct 418 YGAREQPLAGVSGASVAEHVSVPVRYLPDFSAAAEQVAAAAAPGDVIVTMGAGDVTLLGP 477 Query 473 EILTALRVRANRSAPG 488 EI+TALRVRANR APG Sbjct 478 EIVTALRVRANRGAPG 493 >gi|41407994|ref|NP_960830.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium avium subsp. paratuberculosis K-10] gi|48428301|sp|P61681.1|MURC_MYCPA RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|41396348|gb|AAS04213.1| MurC [Mycobacterium avium subsp. paratuberculosis K-10] Length=496 Score = 776 bits (2003), Expect = 0.0, Method: Compositional matrix adjust. Identities = 414/496 (84%), Positives = 447/496 (91%), Gaps = 11/496 (2%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++T+QLP +L RVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRG+HALRARGA IRI Sbjct 1 MTTDQLPAELERVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGIHALRARGAQIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGG TAV+TTHAAIPKTNPELVEARRRGIPV+LRPAVLAKLM GRTTLMV Sbjct 61 GHDASSLDLLPGGPTAVITTHAAIPKTNPELVEARRRGIPVILRPAVLAKLMDGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCG DPSFAVGGE+GEAGTNAHHGSGDCFVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMLIVALQHCGRDPSFAVGGEMGEAGTNAHHGSGDCFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTP VAV+TNIE+DHLDFYGS +AYVAVFD+FVER+ PGGALVVC DDPG AALA+R E Sbjct 181 YTPDVAVVTNIETDHLDFYGSADAYVAVFDAFVERLAPGGALVVCVDDPGAAALARRTAE 240 Query 241 LGIRVLRYGS------VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVP 294 LGIRVLRYGS G+ +AATLVSWQQQG AVA IRLA E Q P VMRLSVP Sbjct 241 LGIRVLRYGSGSHGQAPSGQPLAATLVSWQQQGTEAVAQIRLAGE---QQHPLVMRLSVP 297 Query 295 GRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCG--VGKASVRVFDDY 352 GRHMALNA+GALLAA++IGAP + VLDGLAGFEGVRRRFELVGT G ++VRVFDDY Sbjct 298 GRHMALNAMGALLAAIEIGAPTEAVLDGLAGFEGVRRRFELVGTAGGPAPSSTVRVFDDY 357 Query 353 AHHPTEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDV 412 AHHPTEI+ATLAA R +LEQ GGR + VFQPHLYSRTKAFA EFGRAL+AADEVFVLDV Sbjct 358 AHHPTEIAATLAAVRTLLEQSGGGRSIAVFQPHLYSRTKAFAEEFGRALDAADEVFVLDV 417 Query 413 YGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGP 472 YGAREQPLAGVSGASVAEHV+VP+RY+PDFSA A+QVAAAA+PGDVIVTMGAGDVTLLGP Sbjct 418 YGAREQPLAGVSGASVAEHVSVPVRYLPDFSAAAEQVAAAAAPGDVIVTMGAGDVTLLGP 477 Query 473 EILTALRVRANRSAPG 488 EI+TALRVRANR APG Sbjct 478 EIVTALRVRANRGAPG 493 >gi|296166019|ref|ZP_06848471.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898640|gb|EFG78194.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=486 Score = 759 bits (1960), Expect = 0.0, Method: Compositional matrix adjust. Identities = 418/493 (85%), Positives = 445/493 (91%), Gaps = 8/493 (1%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++ EQLPP+L RVHMVGIGGAGMSGIARILLDRG LVSGSDAKESRGVHALRARGA IRI Sbjct 1 MNPEQLPPELHRVHMVGIGGAGMSGIARILLDRGALVSGSDAKESRGVHALRARGASIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGG TAV+TTHAAIPKTNPELVEARRRGIPV+LRPAVLA+LM GRTTLMV Sbjct 61 GHDASSLDLLPGGPTAVITTHAAIPKTNPELVEARRRGIPVILRPAVLARLMEGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCG DPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMLIVALQHCGRDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTP+VAV+TNIE+DHLDFYGS +AYV VFD+FVER+ PGGALVVC DDPG AALA+R E Sbjct 181 YTPNVAVVTNIETDHLDFYGSADAYVGVFDAFVERLAPGGALVVCVDDPGAAALAERTAE 240 Query 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 LGIRVLRYGS PG AATL+SW+QQG AVAHI+LA E PRVMRLSVPGRHMAL Sbjct 241 LGIRVLRYGSGPGGDHAATLLSWEQQGTEAVAHIQLAGE----SHPRVMRLSVPGRHMAL 296 Query 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 NALGALLAAV+IGA D VLDGLAGFEGVRRRFELVG G SVRVFDDYAHHPTEIS Sbjct 297 NALGALLAAVEIGASVDAVLDGLAGFEGVRRRFELVGNAG----SVRVFDDYAHHPTEIS 352 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 ATLAA R VLEQ GGR +VVFQPHLYSRTK FA FGRAL+AADEVFVLDVYGAREQPL Sbjct 353 ATLAAVRTVLEQSGGGRSLVVFQPHLYSRTKEFAELFGRALDAADEVFVLDVYGAREQPL 412 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 AGVSGASVAEHV+VP+RY+P+FSAVA+QVAAAA PGDVIVTMGAGDVTLL PEI+T LR+ Sbjct 413 AGVSGASVAEHVSVPVRYLPNFSAVAEQVAAAAGPGDVIVTMGAGDVTLLAPEIVTELRI 472 Query 481 RANRSAPGRPGVL 493 R NRSAPGRPGVL Sbjct 473 RDNRSAPGRPGVL 485 >gi|240168216|ref|ZP_04746875.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium kansasii ATCC 12478] Length=488 Score = 755 bits (1950), Expect = 0.0, Method: Compositional matrix adjust. Identities = 417/495 (85%), Positives = 449/495 (91%), Gaps = 10/495 (2%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++TEQLPP+L+RVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRG+HALRARGALIRI Sbjct 1 MNTEQLPPELQRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGLHALRARGALIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDA+SLDLLPGG TAV+TT AAIPKTNPELVEARRRGIPV+LRP VLAKLMAGRTTLMV Sbjct 61 GHDAASLDLLPGGVTAVITTRAAIPKTNPELVEARRRGIPVLLRPVVLAKLMAGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCG DPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMLIVALQHCGRDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTP VAV+TNIESDHLDFYGS EAYV VFDSFVER+ PGGALVVCTDDPG A LA+R+ E Sbjct 181 YTPDVAVVTNIESDHLDFYGSTEAYVGVFDSFVERLAPGGALVVCTDDPGAAELARRSAE 240 Query 241 LGIRVLRYGSV--PGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHM 298 LGIRVLRYGS G +AATL+SW+Q+G AVAH+RLA E + PRVMRL+VPGRHM Sbjct 241 LGIRVLRYGSAEPEGAPLAATLLSWEQRGTEAVAHLRLAGE----RHPRVMRLAVPGRHM 296 Query 299 ALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTE 358 ALNALGALLAA+++ A DEVLDGLAGFEGVRRRFELVG G SVRVFDDYAHHPTE Sbjct 297 ALNALGALLAAIEVDAAIDEVLDGLAGFEGVRRRFELVGAVG----SVRVFDDYAHHPTE 352 Query 359 ISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQ 418 I ATLAA R VL+ G GR +VVFQPHLYSRTKAFAAEFGRAL+AAD VFVLDVYGAREQ Sbjct 353 IGATLAAVRSVLQHGGTGRLLVVFQPHLYSRTKAFAAEFGRALSAADAVFVLDVYGAREQ 412 Query 419 PLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTAL 478 PLAGVSGASVA HV+VP+RY+PDFSAVA +VAAAA PGDVIVTMGAGDVTLLGPEI+TAL Sbjct 413 PLAGVSGASVAGHVSVPVRYLPDFSAVAGEVAAAAGPGDVIVTMGAGDVTLLGPEIVTAL 472 Query 479 RVRANRSAPGRPGVL 493 RV+ANR APGRPGVL Sbjct 473 RVQANRGAPGRPGVL 487 >gi|118463520|ref|YP_881541.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium avium 104] gi|166224703|sp|A0QF53.1|MURC_MYCA1 RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|118164807|gb|ABK65704.1| UDP-N-acetylmuramate--alanine ligase [Mycobacterium avium 104] Length=496 Score = 755 bits (1949), Expect = 0.0, Method: Compositional matrix adjust. Identities = 416/496 (84%), Positives = 447/496 (91%), Gaps = 11/496 (2%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++T+QLP +L RVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRG+HALRARGA IRI Sbjct 1 MTTDQLPAELERVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGIHALRARGAQIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGG TAV+TTHAAIPKTNPELVEARRRGIPV+LRPAVLAKLM GRTTLMV Sbjct 61 GHDASSLDLLPGGPTAVITTHAAIPKTNPELVEARRRGIPVILRPAVLAKLMDGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCG DPSFAVGGE+GEAGTNAHHGSGDCFVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMLIVALQHCGRDPSFAVGGEMGEAGTNAHHGSGDCFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTP VAV+TNIE+DHLDFYGS +AYVAVFD+FVER+ PGGALVVC DDPG AALA+R E Sbjct 181 YTPDVAVVTNIETDHLDFYGSADAYVAVFDAFVERLAPGGALVVCVDDPGAAALARRTAE 240 Query 241 LGIRVLRYGSVP------GETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVP 294 LGIRVLRYGS P GE +AATLVSWQQQG AVA IRLA E Q P VMRLSVP Sbjct 241 LGIRVLRYGSGPHGQAPSGEPLAATLVSWQQQGTEAVAQIRLAGE---QQHPLVMRLSVP 297 Query 295 GRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCG--VGKASVRVFDDY 352 GRHMALNALGALLAA++IGAP + VLDGLAGFEGVRRRFELVGT G ++VRVFDDY Sbjct 298 GRHMALNALGALLAAIEIGAPTEAVLDGLAGFEGVRRRFELVGTAGGSAPSSTVRVFDDY 357 Query 353 AHHPTEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDV 412 AHHPTEI+ATLAA R +LEQ GGR + VFQPHLYSRTKAFA EFG AL+AADEVFVLDV Sbjct 358 AHHPTEIAATLAAVRTLLEQSGGGRSIAVFQPHLYSRTKAFAEEFGHALDAADEVFVLDV 417 Query 413 YGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGP 472 YGAREQPLAGVSGASVAEHV+VP+RY+PDFSA A+QVAAAA+PGDVIVTMGAGDVTLLGP Sbjct 418 YGAREQPLAGVSGASVAEHVSVPVRYLPDFSAAAEQVAAAAAPGDVIVTMGAGDVTLLGP 477 Query 473 EILTALRVRANRSAPG 488 EI+TALRVRANR APG Sbjct 478 EIVTALRVRANRGAPG 493 >gi|254775010|ref|ZP_05216526.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium avium subsp. avium ATCC 25291] Length=496 Score = 752 bits (1942), Expect = 0.0, Method: Compositional matrix adjust. Identities = 414/496 (84%), Positives = 446/496 (90%), Gaps = 11/496 (2%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++T+QLP +L RVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRG+HALRARGA IRI Sbjct 1 MTTDQLPAELERVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGIHALRARGAQIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGG TAV+TTHAAIPKTNPELVEARRRGIPV+LRPAVLAKLM GRTTLMV Sbjct 61 GHDASSLDLLPGGPTAVITTHAAIPKTNPELVEARRRGIPVILRPAVLAKLMDGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCG DPSFAVGGE+GEAGTNAHHGSGDCFVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMLIVALQHCGRDPSFAVGGEMGEAGTNAHHGSGDCFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTP VAV+TNIE+DHLDFYGS +AY+AVFD+FVER+ PGGALVVC DDPG AALA+R E Sbjct 181 YTPDVAVVTNIETDHLDFYGSADAYIAVFDAFVERLAPGGALVVCVDDPGAAALARRTAE 240 Query 241 LGIRVLRYGS------VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVP 294 LGIRVLRYGS GE +AATLVSWQQQG AVA IRLA E Q P VMRLSVP Sbjct 241 LGIRVLRYGSGSHGQAPSGEPLAATLVSWQQQGTEAVAQIRLAGE---QQHPLVMRLSVP 297 Query 295 GRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCG--VGKASVRVFDDY 352 GRHMALNALGALLAA++IGAP + VLDGLAGFEGVRRRFELVGT G ++VRVFDDY Sbjct 298 GRHMALNALGALLAAIEIGAPTEAVLDGLAGFEGVRRRFELVGTAGGSAPSSTVRVFDDY 357 Query 353 AHHPTEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDV 412 AHHPTEI+ATLAA R +LEQ GGR + VFQPHLYSRTKAFA EFG AL+AADEVFVLDV Sbjct 358 AHHPTEIAATLAAVRTLLEQSGGGRSIAVFQPHLYSRTKAFAEEFGHALDAADEVFVLDV 417 Query 413 YGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGP 472 YGAREQPLAGVSGASVAEHV+VP+RY+PDFSA A+QVAAAA+PGDVIVTMGAGDVTLLGP Sbjct 418 YGAREQPLAGVSGASVAEHVSVPVRYLPDFSAAAEQVAAAAAPGDVIVTMGAGDVTLLGP 477 Query 473 EILTALRVRANRSAPG 488 EI+TALRVRANR APG Sbjct 478 EIVTALRVRANRGAPG 493 >gi|183983182|ref|YP_001851473.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium marinum M] gi|229620048|sp|B2HGR5.1|MURC_MYCMM RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|183176508|gb|ACC41618.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium marinum M] Length=488 Score = 731 bits (1888), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/495 (82%), Positives = 440/495 (89%), Gaps = 10/495 (2%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++ EQLPP+L+RVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI Sbjct 1 MTAEQLPPELQRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDAS+LDLLPGG T+V+TTHAAIPKTNPELVEA RRGIPV+LRP VLAKLM GRTT+MV Sbjct 61 GHDASALDLLPGGVTSVITTHAAIPKTNPELVEASRRGIPVMLRPLVLAKLMDGRTTVMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSM+IVALQHCG DPSFAVGGELGEAGTNAHHGSGD FVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMVIVALQHCGRDPSFAVGGELGEAGTNAHHGSGDYFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTPHVAV+TNIE+DHLDFYGS EAYV VFD+FVER+ PGGALVVC DDPG AALA+R+ E Sbjct 181 YTPHVAVVTNIEADHLDFYGSTEAYVGVFDAFVERLAPGGALVVCADDPGSAALAERSAE 240 Query 241 LGIRVLRYGS--VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHM 298 LGIRVLRYGS +AATLVSW+Q+G GAVA I+LA E PR MRLSVPGRHM Sbjct 241 LGIRVLRYGSAGHAEAALAATLVSWEQRGTGAVAQIQLAGE----ADPRSMRLSVPGRHM 296 Query 299 ALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTE 358 ALNALGALLAA+++GAP EVLDGLAGFEGVRRRFELVGT SVRVFDDYAHHPTE Sbjct 297 ALNALGALLAAIEVGAPVGEVLDGLAGFEGVRRRFELVGTA----ESVRVFDDYAHHPTE 352 Query 359 ISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQ 418 + ATL A R V+ Q GR +VVFQPHLYSRTKAFAAEFG AL+AADEVFVLDVY AREQ Sbjct 353 VRATLEAVRSVVRQSGSGRLLVVFQPHLYSRTKAFAAEFGSALDAADEVFVLDVYAAREQ 412 Query 419 PLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTAL 478 PL G+SGASVAEHVTVP+RY+ DFSAVA+ VAAAA PGDV+VTMGAGDVTLLGPEI+ AL Sbjct 413 PLTGISGASVAEHVTVPVRYLRDFSAVAEVVAAAAGPGDVVVTMGAGDVTLLGPEIVAAL 472 Query 479 RVRANRSAPGRPGVL 493 R+RA+RS PGRPGVL Sbjct 473 RMRADRSEPGRPGVL 487 >gi|118618794|ref|YP_907126.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium ulcerans Agy99] gi|166224709|sp|A0PTI6.1|MURC_MYCUA RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|118570904|gb|ABL05655.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium ulcerans Agy99] Length=488 Score = 723 bits (1865), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/495 (81%), Positives = 437/495 (89%), Gaps = 10/495 (2%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++ EQLPP+L+RVHMVGIGGAGM+GIARILLDRGGLVSGSDAKESRGVHALRARGALIRI Sbjct 1 MTAEQLPPELQRVHMVGIGGAGMAGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDAS+LDLLPGG T+V+TTHAAIPKTNPELVEARRRG+PV+LRP VLAKLM GR T+MV Sbjct 61 GHDASALDLLPGGVTSVITTHAAIPKTNPELVEARRRGVPVMLRPVVLAKLMDGRITVMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSM IVALQHCG DPSFAVGGELGEAGTNAHHGSGD FVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMAIVALQHCGRDPSFAVGGELGEAGTNAHHGSGDYFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTPHVAV+TNIE+DHLDFYGS EAYV VFD+FVER+ PGGALVVC DDPG AALA+R+ E Sbjct 181 YTPHVAVVTNIEADHLDFYGSTEAYVGVFDAFVERLAPGGALVVCADDPGSAALAERSAE 240 Query 241 LGIRVLRY--GSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHM 298 LGIRVLRY G +AATLVSW+Q+G GAVA I+LA E PR MRLSVPGRHM Sbjct 241 LGIRVLRYGSAGHAGAALAATLVSWEQRGTGAVAQIQLAGE----ADPRSMRLSVPGRHM 296 Query 299 ALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTE 358 ALN LGALLAA+++GAP EVLDGLAGFEGVRRRFELVGT SVRVFDDYAHHPTE Sbjct 297 ALNVLGALLAAIEVGAPVGEVLDGLAGFEGVRRRFELVGTA----ESVRVFDDYAHHPTE 352 Query 359 ISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQ 418 + ATL A R V+ Q GR +VVFQPHLYSRTKAFAAEFG AL+AADEVFVLDVY AREQ Sbjct 353 VRATLEAVRSVVRQSGSGRLLVVFQPHLYSRTKAFAAEFGSALDAADEVFVLDVYAAREQ 412 Query 419 PLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTAL 478 PL G+SGASVAEHVTVP+RY+ DFSAVA+ VAAAA PGDV+VTMGAGDVTLLGPEI+ AL Sbjct 413 PLTGISGASVAEHVTVPVRYLRDFSAVAEVVAAAAGPGDVVVTMGAGDVTLLGPEIVAAL 472 Query 479 RVRANRSAPGRPGVL 493 R+RA+RS PGRPGVL Sbjct 473 RMRADRSEPGRPGVL 487 >gi|15827435|ref|NP_301698.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium leprae TN] gi|221229912|ref|YP_002503328.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium leprae Br4923] gi|13431702|sp|P57994.1|MURC_MYCLE RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|254766014|sp|B8ZQQ1.1|MURC_MYCLB RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|13092985|emb|CAC31296.1| UDP-N-acetyl-muramate-alanine ligase [Mycobacterium leprae] gi|219933019|emb|CAR71010.1| UDP-N-acetyl-muramate-alanine ligase [Mycobacterium leprae Br4923] Length=495 Score = 710 bits (1832), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/494 (80%), Positives = 431/494 (88%), Gaps = 9/494 (1%) Query 5 QLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDA 64 QLPP+L+RVHMVGIGG+GMSGIARILLDRGGLVSGSDAKESR VHALRARGALIRIGHDA Sbjct 5 QLPPELQRVHMVGIGGSGMSGIARILLDRGGLVSGSDAKESRVVHALRARGALIRIGHDA 64 Query 65 SSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTH 124 S LDLLPGGATAV+T AIPKTNPELVEARRRGIPV+LR AVLA+LM G TTLMV GTH Sbjct 65 SLLDLLPGGATAVITIRTAIPKTNPELVEARRRGIPVLLRSAVLARLMDGCTTLMVAGTH 124 Query 125 GKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPH 184 GKTTTTSML+VALQHCG DPSF VGGEL GTNAHHG G CFVAEADESDGSLL+YTP+ Sbjct 125 GKTTTTSMLVVALQHCGCDPSFVVGGELAVVGTNAHHGLGACFVAEADESDGSLLEYTPN 184 Query 185 VAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIR 244 VAV+TNI+SDHLDFYGSV+AY+ VFDSFVER GGALVVC DDPG AALA+R ELGIR Sbjct 185 VAVVTNIDSDHLDFYGSVDAYIRVFDSFVERFALGGALVVCNDDPGAAALARRTAELGIR 244 Query 245 VLRYGSVP--GETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNA 302 VLRYGS GET+AA L+SW+QQG GAVAHI+LA + RVMRL VPGRHMALNA Sbjct 245 VLRYGSDDRIGETLAARLLSWEQQGTGAVAHIQLAGQ----PNSRVMRLPVPGRHMALNA 300 Query 303 LGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKAS---VRVFDDYAHHPTEI 359 LGALLAA++IGA DEVLDGLAGF GVRRRFELVGT GVG+AS VRVFDDYAHHPTEI Sbjct 301 LGALLAAIEIGASTDEVLDGLAGFRGVRRRFELVGTSGVGQASNSLVRVFDDYAHHPTEI 360 Query 360 SATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQP 419 SATLAA R++LEQ GGRC+VVFQPHLYSRTKA + EFGRAL+AADEVF++ V GAREQP Sbjct 361 SATLAAFRIMLEQSGGGRCIVVFQPHLYSRTKALSREFGRALSAADEVFIVGVNGAREQP 420 Query 420 LAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALR 479 LAGVSGASVA+HV+VP+RY+PD+SAV +VAAAA PGDVIVTMG GDV LLGPEI+ ALR Sbjct 421 LAGVSGASVAKHVSVPVRYIPDYSAVVIEVAAAAGPGDVIVTMGIGDVGLLGPEIVAALR 480 Query 480 VRANRSAPGRPGVL 493 VRAN + PG GVL Sbjct 481 VRANCNTPGCSGVL 494 >gi|108800221|ref|YP_640418.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium sp. MCS] gi|119869349|ref|YP_939301.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium sp. KMS] gi|126435844|ref|YP_001071535.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium sp. JLS] 6 more sequence titles Length=484 Score = 702 bits (1813), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/488 (80%), Positives = 420/488 (87%), Gaps = 8/488 (1%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 +ST LP +LRRVHMVGIGGAGMSGIARILLDRG +VSGSDAKESR V ALRARGA IRI Sbjct 1 MSTPPLPDELRRVHMVGIGGAGMSGIARILLDRGAMVSGSDAKESRAVVALRARGAAIRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDASSLDLLPGG TAVVTTHAAIPKTNPELVEARRR IP+VLRP VLAKLMAG TTLMV Sbjct 61 GHDASSLDLLPGGPTAVVTTHAAIPKTNPELVEARRRAIPIVLRPVVLAKLMAGHTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 TGTHGKTTTTSMLIVALQHCG DPSFAVGG+LGEAGTNAHHGSG+CFVAEADESDGSLL+ Sbjct 121 TGTHGKTTTTSMLIVALQHCGFDPSFAVGGDLGEAGTNAHHGSGECFVAEADESDGSLLE 180 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE 240 YTP VAV+TNIE+DHLDF+GS EAY AVFD+FVER+ PGGAL+ C DDPG AALA+R Sbjct 181 YTPDVAVVTNIEADHLDFFGSAEAYTAVFDAFVERLTPGGALIACVDDPGSAALAERTAA 240 Query 241 LGIRVLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMAL 300 LG+RVLRYGS G +A LV W+QQG GAVAHI+LA E A PR MRLSVPGRHMAL Sbjct 241 LGVRVLRYGSAGGRDLAGALVGWEQQGTGAVAHIQLAGESA----PRAMRLSVPGRHMAL 296 Query 301 NALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEIS 360 NALGALLAA+Q+GA D VLDGLAGFEGVRRRFELVGT VRVFDDYAHHPTE++ Sbjct 297 NALGALLAALQVGADPDTVLDGLAGFEGVRRRFELVGTA----TGVRVFDDYAHHPTEVA 352 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 ATLAA R V +Q GR +VVFQPHLYSRT+ FA EFG AL+AAD VFVLDVYGAREQP+ Sbjct 353 ATLAALRAVTDQAGDGRAVVVFQPHLYSRTETFAREFGAALSAADLVFVLDVYGAREQPI 412 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRV 480 AGVSGAS+ EHV VP+ YVPDFSAVA QVA A PGDV+VTMGAGDVT+LGPEI+ AL+ Sbjct 413 AGVSGASIVEHVGVPVTYVPDFSAVAAQVAGAVRPGDVVVTMGAGDVTMLGPEIIAALQA 472 Query 481 RANRSAPG 488 RANR+ PG Sbjct 473 RANRTVPG 480 >gi|118469061|ref|YP_888503.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium smegmatis str. MC2 155] gi|166224705|sp|A0R015.1|MURC_MYCS2 RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|118170348|gb|ABK71244.1| UDP-N-acetylmuramate--alanine ligase [Mycobacterium smegmatis str. MC2 155] Length=482 Score = 702 bits (1811), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/484 (79%), Positives = 416/484 (86%), Gaps = 10/484 (2%) Query 5 QLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDA 64 LPP+L+RVHMVGIGGAGMSG+ARILLDRGGLVSGSDAKESRGV ALRARGA IRIGHDA Sbjct 5 SLPPELQRVHMVGIGGAGMSGVARILLDRGGLVSGSDAKESRGVVALRARGAEIRIGHDA 64 Query 65 SSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTH 124 SSLDLLPGG TAVVTTHAAIPKTNPELVEAR+RGIPV+LRP VLAKLM G TTLMVTGTH Sbjct 65 SSLDLLPGGPTAVVTTHAAIPKTNPELVEARKRGIPVILRPVVLAKLMTGYTTLMVTGTH 124 Query 125 GKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPH 184 GKTTTTSMLIVALQH G DPSFAVGGELGEAGTNAHHGSG FVAEADESDGSLL+YTP+ Sbjct 125 GKTTTTSMLIVALQHSGFDPSFAVGGELGEAGTNAHHGSGTTFVAEADESDGSLLEYTPN 184 Query 185 VAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIR 244 VAV+TNIE+DHLDF+GS +AY AVFDSFVERI PGGALVVCTDDPG AALA R LGIR Sbjct 185 VAVVTNIEADHLDFFGSEQAYTAVFDSFVERIAPGGALVVCTDDPGAAALADRTDALGIR 244 Query 245 VLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALG 304 VLRYGS G+ +A TL+SW+QQG GAVAHIRLA E PR +RLSVPGRHMALNAL Sbjct 245 VLRYGST-GDNLAGTLLSWEQQGTGAVAHIRLAGE----HNPRAVRLSVPGRHMALNALA 299 Query 305 ALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLA 364 ALLAA +IGAP D VLDGLAGFEGVRRRFELVGT A RVFDDYAHHPTE+ ATL Sbjct 300 ALLAAREIGAPTDSVLDGLAGFEGVRRRFELVGTA----AGARVFDDYAHHPTEVRATLE 355 Query 365 AARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVS 424 AAR V++Q +GGR +V FQPHLYSRT FA EFG AL+ AD+V VLDVY AREQP+AGVS Sbjct 356 AARTVVDQ-NGGRVVVAFQPHLYSRTATFAHEFGAALSVADQVVVLDVYAAREQPMAGVS 414 Query 425 GASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRANR 484 GA+VA+HVT P+ YVPDFSAVA VA+ A GDVI+TMGAGDVT+LG EIL+ LR++ NR Sbjct 415 GATVADHVTAPVTYVPDFSAVAAHVASIARSGDVILTMGAGDVTMLGGEILSELRLKDNR 474 Query 485 SAPG 488 PG Sbjct 475 GMPG 478 >gi|333990384|ref|YP_004522998.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium sp. JDM601] gi|333486352|gb|AEF35744.1| UDP-N-acetylmuramate-alanine ligase MurC [Mycobacterium sp. JDM601] Length=494 Score = 699 bits (1803), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/499 (79%), Positives = 431/499 (87%), Gaps = 11/499 (2%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 +ST+QLPP+L RVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRG HALRARGA +RI Sbjct 1 MSTDQLPPELSRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGTHALRARGAQVRI 60 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHDAS+LDLLPGG T VVTTHAAIPKTNPELVEARRRGIPVVLRPAVLA LMAGRTTLMV Sbjct 61 GHDASALDLLPGGVTTVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAMLMAGRTTLMV 120 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELG----EAGTNAHHGSGDCFVAEADESDG 176 TGTHGKTTTTSML+VALQHCGLDPSFAVGGELG EAGTNAHHGSG FVAEADESDG Sbjct 121 TGTHGKTTTTSMLVVALQHCGLDPSFAVGGELGSAGAEAGTNAHHGSGPLFVAEADESDG 180 Query 177 SLLQYTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQ 236 SLL+YTP+VAV+TN+E+DHLDF+GS EAY VFDSF+ERI PGGA VVC DDPG A LA Sbjct 181 SLLEYTPNVAVVTNVEADHLDFFGSAEAYTRVFDSFMERITPGGAAVVCVDDPGAAELAD 240 Query 237 RATELGIRVLRYGSV-PGET-MAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVP 294 R GIRVLRYG+ PG+ +A +L+SW+QQG GAVA I LA + MRL+VP Sbjct 241 RTAAQGIRVLRYGTERPGQQELAGSLLSWEQQGTGAVAEIALAGSASR----EAMRLAVP 296 Query 295 GRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAH 354 GRHMALNALGALLAAV++GAP VLDGLAGF+GVRRRFELVG+ G SVRVFDDYAH Sbjct 297 GRHMALNALGALLAAVEVGAPLQAVLDGLAGFDGVRRRFELVGSAG-SSGSVRVFDDYAH 355 Query 355 HPTEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYG 414 HPTEI+ATL A R +L + GR +VVFQPHLYSRTKAFAAEFGR+LN ADEVFVLDVYG Sbjct 356 HPTEIAATLTAVRALLAERGTGRSLVVFQPHLYSRTKAFAAEFGRSLNGADEVFVLDVYG 415 Query 415 AREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEI 474 AREQPL GVSGASVAEHV+VP+ Y+PDF+AV Q VAAAA PGDVIVTMGAGDVT+LGPEI Sbjct 416 AREQPLPGVSGASVAEHVSVPVHYLPDFAAVPQAVAAAAGPGDVIVTMGAGDVTVLGPEI 475 Query 475 LTALRVRANRSAPGRPGVL 493 +TALR R++R+ PGRPG L Sbjct 476 VTALRARSDRTLPGRPGAL 494 >gi|315443923|ref|YP_004076802.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium sp. Spyr1] gi|315262226|gb|ADT98967.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium sp. Spyr1] Length=475 Score = 646 bits (1667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/478 (75%), Positives = 398/478 (84%), Gaps = 10/478 (2%) Query 5 QLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDA 64 LPP+L RVHMVGIGGAGMSG+ARILLDRGG VSGSDAK+SRG+ ALRARGA +RIGHD Sbjct 8 SLPPELARVHMVGIGGAGMSGVARILLDRGGQVSGSDAKDSRGLIALRARGAQVRIGHDP 67 Query 65 SSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTH 124 S+LD+LPGG TAVVTTHAAIPKTNPELVEARRRGIPV+LRPAVLA+LM RT+L+VTGTH Sbjct 68 SALDMLPGGPTAVVTTHAAIPKTNPELVEARRRGIPVILRPAVLARLMDDRTSLLVTGTH 127 Query 125 GKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPH 184 GKT+TTSM+IVALQHCG DPSFAVGG+LG+AGTNAHHGSG FVAEADESDGSLL+Y+P Sbjct 128 GKTSTTSMIIVALQHCGFDPSFAVGGDLGQAGTNAHHGSGSTFVAEADESDGSLLEYSPD 187 Query 185 VAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIR 244 VAV+TNIE+DHLDFYG+VE Y AVFD FV+RI PGGALVVC DDPG AALA+R LGIR Sbjct 188 VAVVTNIEADHLDFYGTVENYTAVFDQFVDRIKPGGALVVCVDDPGAAALAERTAALGIR 247 Query 245 VLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALG 304 VLRYGS PG + ATL+ W Q G GAVA I + +E PR MRLSVPGRHMALNALG Sbjct 248 VLRYGSAPG--LDATLLDWSQLGTGAVAEISVRAE----DRPRTMRLSVPGRHMALNALG 301 Query 305 ALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLA 364 ALLAA Q GA D VLDGLAGF+GVRRRFELVGT G VRVFDDYAHHPTE+ A + Sbjct 302 ALLAATQAGAEIDAVLDGLAGFDGVRRRFELVGTAG----GVRVFDDYAHHPTEVRAAIT 357 Query 365 AARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVS 424 A R V EQ G R + VFQPHLYSRT+ FA EF +L+ ADEVFVLDVY AREQPL GVS Sbjct 358 ALRAVAEQTPGARTVAVFQPHLYSRTETFATEFAASLSTADEVFVLDVYAAREQPLPGVS 417 Query 425 GASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRA 482 GA++A+ V+ P+ Y+ DFSAVA +VAAA S GDV+VTMGAGDVT+LG EIL +R RA Sbjct 418 GATIADGVSAPVTYIADFSAVAARVAAAVSAGDVVVTMGAGDVTMLGQEILAEVRARA 475 >gi|145223576|ref|YP_001134254.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium gilvum PYR-GCK] gi|189029001|sp|A4TBE7.1|MURC_MYCGI RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|145216062|gb|ABP45466.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium gilvum PYR-GCK] Length=475 Score = 642 bits (1657), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/478 (74%), Positives = 396/478 (83%), Gaps = 10/478 (2%) Query 5 QLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDA 64 LPP+L RVHMVGIGGAGMSG+ARILLDRGG VSGSDAK+SRG+ ALRARGA +RIGHD Sbjct 8 SLPPELARVHMVGIGGAGMSGVARILLDRGGQVSGSDAKDSRGLIALRARGAQVRIGHDP 67 Query 65 SSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTH 124 S+LD+LPGG TAVVTTHAAIPKTNPELVEARRRGIPV+LRPAVLA+LM RT+L+VTGTH Sbjct 68 SALDMLPGGPTAVVTTHAAIPKTNPELVEARRRGIPVILRPAVLARLMDDRTSLLVTGTH 127 Query 125 GKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPH 184 GKT+TTSM+IVALQHCG DPSFAVGG+LG+AGTNAHHGSG FVAEADESDGSLL+Y+P Sbjct 128 GKTSTTSMIIVALQHCGFDPSFAVGGDLGQAGTNAHHGSGSTFVAEADESDGSLLEYSPD 187 Query 185 VAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIR 244 VAV+TNIE+DHLDFYG+VE Y AVFD FV+RI P GALVVC DDPG AALA+R LGIR Sbjct 188 VAVVTNIEADHLDFYGTVENYTAVFDQFVDRIKPVGALVVCVDDPGAAALAERTAALGIR 247 Query 245 VLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALG 304 VLRYGS PG + ATL+ W Q G GAVA I + +E PR MRLSVPGRHMALNALG Sbjct 248 VLRYGSAPG--LDATLLDWSQLGTGAVAEISVRAE----DRPRTMRLSVPGRHMALNALG 301 Query 305 ALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLA 364 ALLAA Q GA D VLDGLAGF+GVRRRFELVGT G VRVFDDYAHHPTE+ A + Sbjct 302 ALLAATQAGADIDAVLDGLAGFDGVRRRFELVGTAG----GVRVFDDYAHHPTEVRAAIT 357 Query 365 AARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVS 424 A R V EQ G R + VFQPHLYSRT+ FA EF +L+ ADEVFVLDVY AREQPL GVS Sbjct 358 ALRAVAEQTPGARTVAVFQPHLYSRTETFATEFAASLSTADEVFVLDVYAAREQPLPGVS 417 Query 425 GASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRA 482 GA++A+ V+ P+ Y+ DFSAVA +VAA S GDV+VTMGAGDVT+LG EIL +R RA Sbjct 418 GATIADGVSAPVTYIADFSAVAARVAAVVSAGDVVVTMGAGDVTMLGQEILAEVRARA 475 >gi|169629094|ref|YP_001702743.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium abscessus ATCC 19977] gi|226711870|sp|B1MP38.1|MURC_MYCA9 RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|169241061|emb|CAM62089.1| UDP-N-acetylmuramate--L-alanine ligase MurC [Mycobacterium abscessus] Length=490 Score = 635 bits (1639), Expect = 4e-180, Method: Compositional matrix adjust. Identities = 346/491 (71%), Positives = 381/491 (78%), Gaps = 20/491 (4%) Query 6 LPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDAS 65 LP LRRVHMVGIGGAGMSGIARILLDRG VSGSDAKESRGV ALRARGAL+ IGHD Sbjct 6 LPEHLRRVHMVGIGGAGMSGIARILLDRGAQVSGSDAKESRGVLALRARGALVNIGHDGD 65 Query 66 SLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHG 125 +LDLLPGG T VVTTHAAIPKTNPELVEA RRGIPV+LRP VLA LMAG TLMVTGTHG Sbjct 66 ALDLLPGGPTVVVTTHAAIPKTNPELVEANRRGIPVLLRPVVLADLMAGYRTLMVTGTHG 125 Query 126 KTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHV 185 KT+TTSMLIVALQHCG DPSFAVGGEL EAGTNAHHGSGD FVAEADESDGSLLQY P++ Sbjct 126 KTSTTSMLIVALQHCGYDPSFAVGGELNEAGTNAHHGSGDVFVAEADESDGSLLQYRPNL 185 Query 186 AVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRV 245 ++TNIE+DHLD +GSVEAY AVFD F E + G LVVC DDPG AALA+RA E GIRV Sbjct 186 IIVTNIEADHLDHFGSVEAYSAVFDEFAETLGSEGVLVVCLDDPGAAALARRAHERGIRV 245 Query 246 LRYGS--------VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRH 297 YGS VP +A L WQ + GA A I+LA E A PR MRLSVPGRH Sbjct 246 RGYGSADQAEAGDVP---VAGQLRDWQFKDTGATAQIQLAGESA----PRTMRLSVPGRH 298 Query 298 MALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPT 357 MALNAL A++ A +IGA D+VLDGLAGFEGVRRRFELVG+ SVRVFDDYAHHPT Sbjct 299 MALNALAAVVTAAEIGAAVDDVLDGLAGFEGVRRRFELVGSV----ESVRVFDDYAHHPT 354 Query 358 EISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGARE 417 E+ L A ++ Q GR +VVFQPHLYSRT AFA EF AL+ AD VFVLDVYGARE Sbjct 355 EVRTVLQAVSGIVAQQGFGRSVVVFQPHLYSRTAAFATEFADALSIADLVFVLDVYGARE 414 Query 418 QPLAGVSGASVAEHVT-VPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILT 476 PL GV+GA + E + P+ Y+PD S VAQQVAAA +PGD+++TMGAGDVTL G EI+ Sbjct 415 APLPGVTGALIVEQIAGAPVHYLPDLSTVAQQVAAATAPGDLVITMGAGDVTLQGKEIVR 474 Query 477 ALRVRANRSAP 487 ALR RAN P Sbjct 475 ALRARANDWPP 485 >gi|120404494|ref|YP_954323.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium vanbaalenii PYR-1] gi|189029002|sp|A1TAW7.1|MURC_MYCVP RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|119957312|gb|ABM14317.1| UDP-N-acetylmuramate--L-alanine ligase [Mycobacterium vanbaalenii PYR-1] Length=478 Score = 634 bits (1634), Expect = 1e-179, Method: Compositional matrix adjust. Identities = 360/478 (76%), Positives = 397/478 (84%), Gaps = 8/478 (1%) Query 5 QLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDA 64 LP +L+RVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGV ALRARGA IRIGHD Sbjct 9 DLPAELQRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVIALRARGAEIRIGHDP 68 Query 65 SSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTH 124 S+LD+L GG TAVVTTHAAIPKTNPELVEARRRGIPV+LRPAVLA+LMAG TTLMVTGTH Sbjct 69 SALDMLAGGPTAVVTTHAAIPKTNPELVEARRRGIPVLLRPAVLARLMAGHTTLMVTGTH 128 Query 125 GKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPH 184 GKTTTTSMLIVALQH G DPSFAVGG+LGEAGTNAHHGSG FVAEADESDGSLL+Y P Sbjct 129 GKTTTTSMLIVALQHSGFDPSFAVGGDLGEAGTNAHHGSGSSFVAEADESDGSLLEYRPD 188 Query 185 VAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIR 244 + V+TNIE+DHLDF+GSVEAY VFD F RI PGGALVVC DDPG ALA+R + G+R Sbjct 189 IVVVTNIEADHLDFFGSVEAYTEVFDRFAGRIDPGGALVVCVDDPGARALAERLSGSGLR 248 Query 245 VLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALG 304 VLRYGS + ATL+ W QQG GAVA I L +E P MRLSVPGRHMALNALG Sbjct 249 VLRYGSTGTGALDATLLEWTQQGTGAVASIALRTE----ARPLTMRLSVPGRHMALNALG 304 Query 305 ALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLA 364 ALLAA + GA + VLDGLAGFEGVRRRFELVG+ VRVFDDYAHHPTE+ ATL Sbjct 305 ALLAAREAGADLESVLDGLAGFEGVRRRFELVGSAN----GVRVFDDYAHHPTEVRATLT 360 Query 365 AARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVS 424 A R V++Q GR +VVFQPHLYSRT FA+EFG AL+AADEVFVLDVY AREQPLAGVS Sbjct 361 ALRAVVDQAGSGRAIVVFQPHLYSRTVTFASEFGAALSAADEVFVLDVYAAREQPLAGVS 420 Query 425 GASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVRA 482 GA+VA+ V+ P+ Y+PDFSAVA +VAA+ +PGDV+VTMGAGDVTLLG EIL + RA Sbjct 421 GATVADAVSAPVTYLPDFSAVAARVAASVAPGDVVVTMGAGDVTLLGREILAEVEARA 478 >gi|312140141|ref|YP_004007477.1| UDP-N-acetylmuramate-l-alanine ligase murc [Rhodococcus equi 103S] gi|325676978|ref|ZP_08156650.1| UDP-N-acetylmuramate--L-alanine ligase [Rhodococcus equi ATCC 33707] gi|311889480|emb|CBH48797.1| UDP-N-acetylmuramate-L-alanine ligase MurC [Rhodococcus equi 103S] gi|325552278|gb|EGD21968.1| UDP-N-acetylmuramate--L-alanine ligase [Rhodococcus equi ATCC 33707] Length=498 Score = 607 bits (1566), Expect = 1e-171, Method: Compositional matrix adjust. Identities = 334/493 (68%), Positives = 379/493 (77%), Gaps = 18/493 (3%) Query 3 TEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGH 62 +EQLP L RVHMVGIGGAGMSGIARILL RGG VSGSDAKESRGV +LRARGA++RIGH Sbjct 2 SEQLPVGLERVHMVGIGGAGMSGIARILLARGGQVSGSDAKESRGVLSLRARGAVVRIGH 61 Query 63 DASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTG 122 DAS+LDLLPGG TAVVTTHAAIPK NPELVEA RGIPV+LRPAVLA LM G TL+V+G Sbjct 62 DASALDLLPGGPTAVVTTHAAIPKDNPELVEAAARGIPVILRPAVLASLMQGHRTLLVSG 121 Query 123 THGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYT 182 THGKT+TTSML+VALQHCG DPSFAVGGEL EAGTNAHHG+GD FVAEADESDGSLLQY Sbjct 122 THGKTSTTSMLVVALQHCGFDPSFAVGGELNEAGTNAHHGTGDVFVAEADESDGSLLQYD 181 Query 183 PHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELG 242 P V ++TN+E+DHLDF+G+ +AYV VFD FV RI PGG LV C DDPG AALA+R E G Sbjct 182 PDVVIVTNVEADHLDFFGTSDAYVQVFDDFVARIAPGGLLVACLDDPGSAALARRTIEAG 241 Query 243 ---IRVLRYGSVPGETMAA------TLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSV 293 +RV+ YG+ G A LVSW+ + G VA IR A E A R +RL V Sbjct 242 RDDVRVVGYGTADGVAAAGPVPVGVELVSWEARDTGGVAQIRFAGEDAA----RTLRLGV 297 Query 294 PGRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYA 353 PG+HMALNAL ALLA GA DE+L+GLAGF GV RRF+ G + VRVFDDYA Sbjct 298 PGKHMALNALAALLAGRGAGASIDELLEGLAGFGGVHRRFQFTGR----ERGVRVFDDYA 353 Query 354 HHPTEISATL-AAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDV 412 HHPTE+ A L AA+ +V + GR +VVFQPHLYSRT FA EFG AL+ ADEV VLDV Sbjct 354 HHPTEVRAVLGAASDLVDDDRQPGRVVVVFQPHLYSRTVTFAQEFGEALDLADEVVVLDV 413 Query 413 YGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGP 472 YGARE+PL GVSGA VA+ VT P+ Y PD S V +QVA+ A PGDV++TMGAGDVT+LG Sbjct 414 YGAREEPLPGVSGALVAQSVTKPVHYQPDRSQVPRQVASLAEPGDVVITMGAGDVTMLGG 473 Query 473 EILTALRVRANRS 485 +IL ALR R N S Sbjct 474 QILDALRARPNGS 486 >gi|111018100|ref|YP_701072.1| UDP-N-acetylmuramate--L-alanine ligase [Rhodococcus jostii RHA1] gi|123145349|sp|Q0SHS2.1|MURC_RHOSR RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|110817630|gb|ABG92914.1| UDP-N-acetylmuramate--L-alanine ligase [Rhodococcus jostii RHA1] Length=503 Score = 591 bits (1524), Expect = 7e-167, Method: Compositional matrix adjust. Identities = 329/500 (66%), Positives = 373/500 (75%), Gaps = 33/500 (6%) Query 5 QLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDA 64 LP +L RVHMVGIGGAGMSGIARILL RGG VSGSDAKESRGV ALRARGA +RIGHDA Sbjct 3 DLPAELERVHMVGIGGAGMSGIARILLARGGQVSGSDAKESRGVLALRARGAQVRIGHDA 62 Query 65 SSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTH 124 +LDLLPGG T VVTTHAAIPK NPELVEA RRGIPV+LRPAVLA LM G TL+V+GTH Sbjct 63 GALDLLPGGPTVVVTTHAAIPKDNPELVEAARRGIPVILRPAVLASLMQGHRTLLVSGTH 122 Query 125 GKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPH 184 GKT+TTSML+VALQHCG DPSFAVGGEL EAGTNAHHGSGD FVAEADESDGSLLQY P Sbjct 123 GKTSTTSMLVVALQHCGFDPSFAVGGELNEAGTNAHHGSGDVFVAEADESDGSLLQYEPD 182 Query 185 VAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATEL--- 241 V V+TN+E+DHLD++GS EAY+ VFD F R+ PGG LV C DDPG AALAQR Sbjct 183 VVVVTNVEADHLDYFGSTEAYIQVFDDFAARLSPGGLLVACLDDPGSAALAQRVAARGLP 242 Query 242 GIRVLRYG----------SVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRL 291 G+RVL YG SV G + A L+S++ + VG V +LA E Q PR +R+ Sbjct 243 GVRVLGYGSAEDADGAFASVDGVEVGARLLSFEARDVGGVLQFQLAGE----QSPRTVRM 298 Query 292 SVPGRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDD 351 VPGRHMALNAL ALLAA + GA DE+L+G+AGF GV RRF+ G + VRVFDD Sbjct 299 GVPGRHMALNALAALLAAREAGADVDEILEGIAGFGGVHRRFQFTGR----EHGVRVFDD 354 Query 352 YAHHPTEISATLAAARMVLEQGD------------GGRCMVVFQPHLYSRTKAFAAEFGR 399 YAHHPTE+ A L AA ++ Q G+ +VVFQPHLYSRT FA EFG Sbjct 355 YAHHPTEVRAVLGAAADLVRQPHEADRRESEDSVRSGKVIVVFQPHLYSRTATFAEEFGH 414 Query 400 ALNAADEVFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVI 459 AL+ ADEV VLDVYGARE+PL GVSGA VA V+ P+ Y PD S +QVAA ASPGDV+ Sbjct 415 ALDLADEVVVLDVYGAREEPLPGVSGALVALSVSKPVHYQPDLSQAPRQVAALASPGDVV 474 Query 460 VTMGAGDVTLLGPEILTALR 479 +TMGAGDVT+LG +IL ALR Sbjct 475 ITMGAGDVTMLGNQILDALR 494 >gi|54023735|ref|YP_117977.1| UDP-N-acetylmuramate--L-alanine ligase [Nocardia farcinica IFM 10152] gi|59798147|sp|Q5YYX8.1|MURC_NOCFA RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|54015243|dbj|BAD56613.1| putative UDP-N-acetylmuramoyl-L-alanine ligase [Nocardia farcinica IFM 10152] Length=501 Score = 589 bits (1518), Expect = 4e-166, Method: Compositional matrix adjust. Identities = 339/499 (68%), Positives = 379/499 (76%), Gaps = 30/499 (6%) Query 3 TEQ---LPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIR 59 TEQ LPP+LRRVHMVGIGGAGMSGIARILL RGG VSGSDAKESRGV ALRARGA +R Sbjct 8 TEQRSALPPELRRVHMVGIGGAGMSGIARILLSRGGEVSGSDAKESRGVLALRARGAQVR 67 Query 60 IGHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLM 119 IGHDA +LDLLPGG TAVVTT+AAIPKTNPELVEA+RR IPV+LRPAVLA LM G TL+ Sbjct 68 IGHDAGALDLLPGGPTAVVTTYAAIPKTNPELVEAQRRDIPVLLRPAVLASLMRGHRTLL 127 Query 120 VTGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLL 179 V+GTHGKT+TTSMLIVALQHCG DPSFAVGGEL EAGTNAHHG+G+ FVAEADESDGSLL Sbjct 128 VSGTHGKTSTTSMLIVALQHCGFDPSFAVGGELNEAGTNAHHGTGEIFVAEADESDGSLL 187 Query 180 QYTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRA- 238 QY P VAV+TNIESDHLDF+GS AY VFD F +R+ GG LVVC DDPG ALA+R Sbjct 188 QYDPDVAVVTNIESDHLDFFGSDAAYTQVFDDFADRLAAGGLLVVCLDDPGSRALAERVG 247 Query 239 ---TELGIRVLRYGSVPGETMAA------TLVSWQQQGVGAVAHIRLASELATAQGPRVM 289 E G+RVL YGS GE A L SW+ + VG VA +L E A PR + Sbjct 248 PRLAERGVRVLGYGS--GELADAPVPVGVRLHSWEPRDVGGVAQFQLGDEPA----PRTL 301 Query 290 RLSVPGRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVF 349 RLSVPGRHMALNAL ALLAA GA DE++ GL GF GV RRF+ VG + VRVF Sbjct 302 RLSVPGRHMALNALAALLAARAAGADLDEIIQGLEGFGGVHRRFQFVGR----ENGVRVF 357 Query 350 DDYAHHPTEISATLAAARMVLEQG--DG-----GRCMVVFQPHLYSRTKAFAAEFGRALN 402 DDYAHHPTE+ A L AA ++EQ DG GR +VVFQPHLYSRT FA EFG AL+ Sbjct 358 DDYAHHPTEVRAVLGAAAALVEQEARDGARSRQGRVIVVFQPHLYSRTATFATEFGAALS 417 Query 403 AADEVFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTM 462 ADEV VLDVYGARE+ + GV+GA VA+ VT P+ Y PD S V +QVA A PGDV++TM Sbjct 418 LADEVVVLDVYGAREKAMPGVNGALVAQAVTAPVHYQPDMSRVGRQVAGLALPGDVVITM 477 Query 463 GAGDVTLLGPEILTALRVR 481 GAGDVT+LG +IL LR R Sbjct 478 GAGDVTMLGSQILDGLRAR 496 >gi|226307038|ref|YP_002766998.1| UDP-N-acetylmuramate--L-alanine ligase [Rhodococcus erythropolis PR4] gi|259509779|sp|C1A0X4.1|MURC_RHOE4 RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|226186155|dbj|BAH34259.1| UDP-N-acetylmuramate--L-alanine ligase [Rhodococcus erythropolis PR4] Length=502 Score = 588 bits (1517), Expect = 5e-166, Method: Compositional matrix adjust. Identities = 327/499 (66%), Positives = 373/499 (75%), Gaps = 33/499 (6%) Query 6 LPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDAS 65 LP L RVHMVGIGGAGMSGIARILL RGGLVSGSDAKESRGV ALRARGA +RIGHDA Sbjct 4 LPAHLERVHMVGIGGAGMSGIARILLSRGGLVSGSDAKESRGVLALRARGAQVRIGHDAD 63 Query 66 SLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHG 125 +LDLLPGG T VVTTHAAIPK NPELVEA RRGIPV+LRPAVLA LM G T +V+GTHG Sbjct 64 ALDLLPGGPTVVVTTHAAIPKDNPELVEAARRGIPVILRPAVLASLMQGNRTFLVSGTHG 123 Query 126 KTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHV 185 KT+TTSML+VALQHCG DPSFAVGGEL EAGTNAHHGSGD FVAEADESDGSLLQY P+V Sbjct 124 KTSTTSMLVVALQHCGFDPSFAVGGELNEAGTNAHHGSGDVFVAEADESDGSLLQYDPNV 183 Query 186 AVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELG--- 242 V+TNIE+DHLD++GSVEAYV VFD FV+++ PGG L+ C DDPG A LA+R G Sbjct 184 IVVTNIEADHLDYFGSVEAYVKVFDDFVDKLRPGGLLIACLDDPGSADLAKRIVASGRSD 243 Query 243 IRVLRYGS--------------VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRV 288 IRVL YGS V G + L+ + VG V +LA E A R Sbjct 244 IRVLGYGSADAQEVEAGTAFEPVDGVEVGVRLLGFHAHDVGGVLQFQLAGENAA----RT 299 Query 289 MRLSVPGRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRV 348 +R++VPGRHMALNAL ALLAA GA +E+++GLAGF GV RRF+ G + VRV Sbjct 300 VRMAVPGRHMALNALAALLAARDAGAETEEIVEGLAGFGGVHRRFQFTGR----ERGVRV 355 Query 349 FDDYAHHPTEISATL-AAARMVLEQGD-------GGRCMVVFQPHLYSRTKAFAAEFGRA 400 FDDYAHHPTE+ A L AAA +V + D GR +VVFQPHLYSRT AFA EF +A Sbjct 356 FDDYAHHPTEVRAVLGAAADLVRPEDDSSSTNSAAGRVIVVFQPHLYSRTAAFAVEFAQA 415 Query 401 LNAADEVFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIV 460 L+ ADEV VLDVYGARE+P+ GVSGA VA+ VT P+ Y PD S +QVAA A PGD+++ Sbjct 416 LDLADEVVVLDVYGAREEPMPGVSGALVAQSVTKPVHYQPDLSQAPKQVAALAHPGDIVI 475 Query 461 TMGAGDVTLLGPEILTALR 479 TMGAGDVT+LG +IL ALR Sbjct 476 TMGAGDVTMLGKQILDALR 494 >gi|226360229|ref|YP_002778007.1| UDP-N-acetylmuramate--L-alanine ligase [Rhodococcus opacus B4] gi|254766018|sp|C1AU54.1|MURC_RHOOB RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|226238714|dbj|BAH49062.1| UDP-N-acetylmuramate--L-alanine ligase [Rhodococcus opacus B4] Length=503 Score = 588 bits (1516), Expect = 7e-166, Method: Compositional matrix adjust. Identities = 327/500 (66%), Positives = 373/500 (75%), Gaps = 33/500 (6%) Query 5 QLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDA 64 LP L RVHMVGIGGAGMSGIARILL RGG VSGSDAKESRGV ALRARGA +RIGHDA Sbjct 3 DLPAQLERVHMVGIGGAGMSGIARILLARGGQVSGSDAKESRGVLALRARGAQVRIGHDA 62 Query 65 SSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTH 124 +LDLLPGG T VVTTHAAIPK NPELVEA RRGIPV+LRPAVLA LM G TL+V+GTH Sbjct 63 GALDLLPGGPTVVVTTHAAIPKDNPELVEAARRGIPVILRPAVLASLMQGHRTLLVSGTH 122 Query 125 GKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPH 184 GKT+TTSML+VALQHCG DPSFAVGGEL EAGTNAHHGSGD FVAEADESDGSLLQY P+ Sbjct 123 GKTSTTSMLVVALQHCGFDPSFAVGGELNEAGTNAHHGSGDVFVAEADESDGSLLQYDPN 182 Query 185 VAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATEL--- 241 V V+TN+E+DHLD++GS EAY+ VFD F R+ GG LV C DDPG AALAQR Sbjct 183 VVVVTNVEADHLDYFGSPEAYIQVFDDFAARLSHGGLLVACLDDPGSAALAQRVAARGLP 242 Query 242 GIRVLRYGS----------VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRL 291 G+RVL YGS + G + A L+S++ + VG V +LA E Q PR +R+ Sbjct 243 GVRVLGYGSAEDADGAFAPIDGVEVGARLLSFEARDVGGVLQFQLAGE----QAPRTIRM 298 Query 292 SVPGRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDD 351 +VPGRHMALNAL ALLAA + GA DE+L+G+AGF GV RRF+ G + VRVFDD Sbjct 299 NVPGRHMALNALAALLAAREAGADVDEILEGIAGFGGVHRRFQFTGR----EHGVRVFDD 354 Query 352 YAHHPTEISATLAAARMVLEQGD------------GGRCMVVFQPHLYSRTKAFAAEFGR 399 YAHHPTE+ A L AA ++ Q G+ +VVFQPHLYSRT FA EFG Sbjct 355 YAHHPTEVRAVLGAAADLVSQPHEADRRESEEPVRSGKVIVVFQPHLYSRTATFAEEFGH 414 Query 400 ALNAADEVFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVI 459 AL+ ADEV VLDVYGARE+PL GVSGA VA V+ P+ Y PD S +QVAA ASPGDV+ Sbjct 415 ALDLADEVMVLDVYGAREEPLPGVSGALVALSVSKPVHYQPDLSQAPRQVAALASPGDVV 474 Query 460 VTMGAGDVTLLGPEILTALR 479 +TMGAGDVT+LG +IL ALR Sbjct 475 ITMGAGDVTMLGNQILDALR 494 >gi|333918999|ref|YP_004492580.1| UDP-N-acetylmuramate--L-alanine ligase [Amycolicicoccus subflavus DQS3-9A1] gi|333481220|gb|AEF39780.1| UDP-N-acetylmuramate--L-alanine ligase [Amycolicicoccus subflavus DQS3-9A1] Length=506 Score = 586 bits (1511), Expect = 3e-165, Method: Compositional matrix adjust. Identities = 306/498 (62%), Positives = 375/498 (76%), Gaps = 19/498 (3%) Query 2 STEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIG 61 S LPP+L+RVHM+GIGGAGMSGIARIL+ RGG VSGSDAK+SR + LRARGA +R+G Sbjct 8 SPTDLPPELQRVHMIGIGGAGMSGIARILMARGGAVSGSDAKDSRVLLDLRARGAEVRVG 67 Query 62 HDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVT 121 HDA++LDL+ GG T VV+T +AIPKTNPELVEA+RRGIP RP VLA LM G T ++V+ Sbjct 68 HDAAALDLIEGGPTMVVSTQSAIPKTNPELVEAQRRGIPTSYRPDVLATLMRGSTPVLVS 127 Query 122 GTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQY 181 GTHGKT+TTS+L+VALQHC LDPSFAVGGEL EAGTNAHHG+G+ FVAEADESDGSLL+Y Sbjct 128 GTHGKTSTTSLLVVALQHCKLDPSFAVGGELNEAGTNAHHGTGEVFVAEADESDGSLLRY 187 Query 182 TPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATEL 241 P VA++TN+E+DHLD++GS EAYV +FD F R+ PGG +VVC DDPG AA A+RA Sbjct 188 EPGVAIVTNVEADHLDYFGSAEAYVRIFDDFAGRMQPGGLMVVCLDDPGAAAFAERAAAR 247 Query 242 GIRVLRYGS---VP-GETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRH 297 GIRV+ YGS VP G + L++W+ + G I +A E PR MRL+VPGRH Sbjct 248 GIRVVGYGSGETVPTGVELGVQLINWEARDGGGAGQIHIAGE----DSPRAMRLAVPGRH 303 Query 298 MALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPT 357 MALNALGA LAA ++GA DE+L+GL GF GVRRRF+ G +A VR+FDDYAHHPT Sbjct 304 MALNALGAFLAAREVGAQTDEILEGLEGFGGVRRRFQYTGR----EAGVRLFDDYAHHPT 359 Query 358 EISATLAAARMVLEQGDG-------GRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVL 410 E+ A L+ A+ ++ Q GR +VVFQPHLYSRT+ FA EF AL+ ADEV VL Sbjct 360 EVRAVLSTAQDMVAQEHAADPATPPGRVVVVFQPHLYSRTQTFAPEFAEALSIADEVIVL 419 Query 411 DVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLL 470 DVYGARE+P+ GV+G +A V P+ + PD S + +QVA A+ GDV++TMGAGDVT+L Sbjct 420 DVYGAREEPVPGVTGELIARQVAKPVYFQPDVSELPRQVAKLANAGDVVLTMGAGDVTML 479 Query 471 GPEILTALRVRANRSAPG 488 GP IL ALR + N PG Sbjct 480 GPSILDALRAKRNHLRPG 497 >gi|296140341|ref|YP_003647584.1| UDP-N-acetylmuramate/alanine ligase [Tsukamurella paurometabola DSM 20162] gi|296028475|gb|ADG79245.1| UDP-N-acetylmuramate/alanine ligase [Tsukamurella paurometabola DSM 20162] Length=495 Score = 578 bits (1490), Expect = 7e-163, Method: Compositional matrix adjust. Identities = 307/490 (63%), Positives = 358/490 (74%), Gaps = 16/490 (3%) Query 3 TEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGH 62 T LP LRRVHMVGIGGAGMSGIARILL RGG VSGSDAKESRGV ALRARGA +++GH Sbjct 5 TAALPERLRRVHMVGIGGAGMSGIARILLARGGQVSGSDAKESRGVVALRARGAQVQVGH 64 Query 63 DASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTG 122 A +LDLLPGG T VVTTHAAIPK NPELVEA RRGIPV+LRP VLA LM G TL+V+G Sbjct 65 SADALDLLPGGPTVVVTTHAAIPKDNPELVEAHRRGIPVILRPEVLADLMEGYRTLLVSG 124 Query 123 THGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYT 182 THGKT+TTSM +V LQHCG +PSFAVGGEL E+GTNA HG+GD FVAEADESDGSLLQY+ Sbjct 125 THGKTSTTSMAVVGLQHCGGNPSFAVGGELNESGTNAFHGTGDVFVAEADESDGSLLQYS 184 Query 183 PHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRA---- 238 P V V+TN+E+DHLDF+GS E YVAVFD+F ERI PGG LVVC DDPG AAL QR Sbjct 185 PDVVVVTNVEADHLDFFGSEEKYVAVFDAFTERIRPGGTLVVCLDDPGSAALGQRTHAAL 244 Query 239 TELGIRVLRYGS------VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLS 292 G+RV YG P T+ A L+ ++ + G + +R + E R + LS Sbjct 245 RARGVRVFGYGEGTHRDLAPDVTLIAELLDYKPRAEGGMLKVRFSDENRQVT-ERAIMLS 303 Query 293 VPGRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDY 352 VPG+HMALNA+ A +A V +G P +V+ G+ F GV RRF+L GT + VRVFDDY Sbjct 304 VPGKHMALNAIAATIAVVNLGYPTAKVIAGIESFGGVHRRFQLRGT----EDGVRVFDDY 359 Query 353 AHHPTEISATL-AAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLD 411 AHHPTE+ A L AAA MV +Q GR +V FQPHLYSRT+ FAAEF AL+ AD V LD Sbjct 360 AHHPTEVRAVLTAAAEMVAKQAVPGRVIVAFQPHLYSRTEQFAAEFAEALSLADHVVALD 419 Query 412 VYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLG 471 VYGARE PL G++G +AE VT + YVP + VA V A PGDV++TMGAGDVT+ G Sbjct 420 VYGAREAPLPGITGERIAEKVTTDVTYVPSQADVAGTVVDIARPGDVVITMGAGDVTMQG 479 Query 472 PEILTALRVR 481 P IL+AL R Sbjct 480 PAILSALAQR 489 >gi|229490346|ref|ZP_04384187.1| UDP-N-acetylmuramate--alanine ligase [Rhodococcus erythropolis SK121] gi|229322636|gb|EEN88416.1| UDP-N-acetylmuramate--alanine ligase [Rhodococcus erythropolis SK121] Length=502 Score = 572 bits (1475), Expect = 4e-161, Method: Compositional matrix adjust. Identities = 327/499 (66%), Positives = 372/499 (75%), Gaps = 33/499 (6%) Query 6 LPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDAS 65 LP L RVHMVGIGGAGMSGIARILL RGGLVSGSDAKESRGV ALRARGA +RIGHDA Sbjct 4 LPAHLERVHMVGIGGAGMSGIARILLSRGGLVSGSDAKESRGVLALRARGAQVRIGHDAD 63 Query 66 SLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHG 125 +LDLLPGG T VVTTHAAIPK NPELVEA RRGIPV+LRPAVLA LM G T +V+GTHG Sbjct 64 ALDLLPGGPTVVVTTHAAIPKDNPELVEAARRGIPVILRPAVLASLMQGNRTFLVSGTHG 123 Query 126 KTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHV 185 KT+TTSML+VALQHCG DPSFAVGGEL EAGTNAHHGSGD FVAEADESDGSLLQY P+V Sbjct 124 KTSTTSMLVVALQHCGFDPSFAVGGELNEAGTNAHHGSGDVFVAEADESDGSLLQYDPNV 183 Query 186 AVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELG--- 242 V+TNIE+DHLD++GSVEAYV VFD FV+++ PGG L+ C DDPG A LA+R G Sbjct 184 IVVTNIEADHLDYFGSVEAYVKVFDDFVDKLRPGGLLIACLDDPGSADLAKRIVVSGRSD 243 Query 243 IRVLRYGS--------------VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRV 288 IRVL YGS V G + L+ + VG V LA E A R Sbjct 244 IRVLGYGSADAQEVEAGTAFEPVDGVEVGVRLLGFHAHDVGGVLQFHLAGESAA----RT 299 Query 289 MRLSVPGRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRV 348 +R++VPGRHMALNAL ALLAA GA +E+++GLAGF GV RRF+ G + VRV Sbjct 300 VRMAVPGRHMALNALAALLAARDAGAETEEIVEGLAGFGGVHRRFQFTGR----ERGVRV 355 Query 349 FDDYAHHPTEISATL-AAARMVLEQGD-------GGRCMVVFQPHLYSRTKAFAAEFGRA 400 FDDYAHHPTE+ A L AAA +V + D GR +VVFQPHLYSRT AFA EF +A Sbjct 356 FDDYAHHPTEVRAVLGAAADLVRPEDDSSSTNSAAGRVIVVFQPHLYSRTAAFAEEFAQA 415 Query 401 LNAADEVFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIV 460 L+ ADEV VLDVYGARE+P+ GVSGA VA+ VT P+ Y PD S +QVAA A PGD+++ Sbjct 416 LDLADEVVVLDVYGAREEPMPGVSGALVAQSVTKPVHYQPDLSQAPKQVAALAHPGDIVI 475 Query 461 TMGAGDVTLLGPEILTALR 479 TMGAGDVT+LG +IL ALR Sbjct 476 TMGAGDVTMLGKQILDALR 494 >gi|262202909|ref|YP_003274117.1| UDP-N-acetylmuramate/alanine ligase [Gordonia bronchialis DSM 43247] gi|262086256|gb|ACY22224.1| UDP-N-acetylmuramate/alanine ligase [Gordonia bronchialis DSM 43247] Length=529 Score = 553 bits (1424), Expect = 3e-155, Method: Compositional matrix adjust. Identities = 287/493 (59%), Positives = 349/493 (71%), Gaps = 21/493 (4%) Query 4 EQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHD 63 + LP LRRVHMVGIGGAGMSG+ARILL RGG VSGSDAK SRG+ LR RGA I++GHD Sbjct 8 DSLPEQLRRVHMVGIGGAGMSGLARILLARGGQVSGSDAKNSRGILELRTRGARIQVGHD 67 Query 64 ASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGT 123 S+LD +PGG + +VTTHAAIPKTNPELV AR RGIP++LRP VLA+LMAG TL++ GT Sbjct 68 PSALDQIPGGPSVIVTTHAAIPKTNPELVAARSRGIPILLRPRVLAELMAGHRTLLIAGT 127 Query 124 HGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTP 183 HGKT+TTSM +VALQHCG DPSFA+GGEL E+GTNAHHG FVAEADESDGSLL+YTP Sbjct 128 HGKTSTTSMAVVALQHCGQDPSFAIGGELNESGTNAHHGHDGVFVAEADESDGSLLEYTP 187 Query 184 HVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAAL----AQRAT 239 V V+TNI+ DHLDF+G++E YVAVFD F +RIV GG LVVC DDPG AAL A R Sbjct 188 DVVVVTNIDVDHLDFFGTIERYVAVFDDFADRIVDGGTLVVCLDDPGAAALGGRVAARLG 247 Query 240 ELGIRVLRYGS------VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSV 293 + G+ VL YG PG A L+SW G A +R + L + L++ Sbjct 248 DRGVAVLGYGEGVHAGLAPGVHHVAHLLSWSASATGGQARVRFTAPLVDEPSEFTVGLTL 307 Query 294 PGRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYA 353 PG+HM+LN +GA++ ++GA V+ G+ F GV RRFE G CG V V DDYA Sbjct 308 PGKHMSLNGIGAIIGCARLGADLAGVISGIGAFGGVHRRFEFRGRCG----GVDVIDDYA 363 Query 354 HHPTEISATLAAAR-MVLEQGDG------GRCMVVFQPHLYSRTKAFAAEFGRALNAADE 406 HHPTE++A L AAR MV + DG GR + VFQPHLYSRT FA EF AL+ AD Sbjct 364 HHPTEVAAVLTAARDMVTARTDGPATGRAGRVIAVFQPHLYSRTMEFAGEFATALDHADA 423 Query 407 VFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGD 466 + DVYGAREQP+ GVSG +A+ + +P ++ PD S +A QVA PGD+++T+GAGD Sbjct 424 AVIADVYGAREQPIPGVSGRIIADRMHIPAQFAPDLSRLAAQVAQITRPGDIVLTLGAGD 483 Query 467 VTLLGPEILTALR 479 +T+ GPEIL AL Sbjct 484 ITMQGPEILAALE 496 >gi|296394963|ref|YP_003659847.1| UDP-N-acetylmuramate/alanine ligase [Segniliparus rotundus DSM 44985] gi|296182110|gb|ADG99016.1| UDP-N-acetylmuramate/alanine ligase [Segniliparus rotundus DSM 44985] Length=475 Score = 545 bits (1405), Expect = 6e-153, Method: Compositional matrix adjust. Identities = 301/477 (64%), Positives = 354/477 (75%), Gaps = 16/477 (3%) Query 9 DLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLD 68 DL RVH VGIGGAGMS +ARILL RG VSGSD K+SR + LRARGA + +GHDA +LD Sbjct 3 DLSRVHFVGIGGAGMSAVARILLARGAGVSGSDLKDSRAITDLRARGAQVLVGHDARALD 62 Query 69 LLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTT 128 L GG TAVV + AAIP+ NPELVEAR+RG+PV+ RP VLA LM G T ++V+GTHGKTT Sbjct 63 FLDGGPTAVVVSQAAIPEDNPELVEARKRGVPVLYRPQVLAALMEGSTRVLVSGTHGKTT 122 Query 129 TTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVI 188 TTS+ + ALQ GLDPSFAVGGELGEAGTNAH GSG+ FVAEADESDGSLL+Y P AV+ Sbjct 123 TTSLTVAALQQAGLDPSFAVGGELGEAGTNAHQGSGNAFVAEADESDGSLLRYQPDAAVV 182 Query 189 TNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRY 248 TN+E+DHLD +GS EAYVAVFD FV +I PGG+L+V DDPG AAL RA G RVL Y Sbjct 183 TNVEADHLDHFGSSEAYVAVFDQFVRQIAPGGSLIVDVDDPGAAALGSRAAAAGTRVLGY 242 Query 249 GSVP---GETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALGA 305 GS G +AA L W G GA RL + + G RV + VPGRHMA NALGA Sbjct 243 GSNQAPAGVLLAARLADWSPHGEGA----RL-TVVFEPGGERVFSIGVPGRHMARNALGA 297 Query 306 LLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLAA 365 +LAAV GA D + G++ F GVRRRF+L G + VRVFDDYAHHPTE++ATLA Sbjct 298 VLAAVFAGASLDGAISGVSAFTGVRRRFQLKGA----ERGVRVFDDYAHHPTEVAATLAG 353 Query 366 ARMVLEQGDG---GRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAG 422 AR ++ DG GR +VVFQPH+YSRT+ FA EF AL AADEV VLDVYGARE+P AG Sbjct 354 ARALVTDPDGSCSGRLVVVFQPHMYSRTRLFATEFAAALEAADEVLVLDVYGAREKPEAG 413 Query 423 VSGASVAEHV-TVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTAL 478 ++GA +A+ V VP R+VP FS+VAQ A+ A PGDV++TMGAGDVTLLG EIL A+ Sbjct 414 ITGALIADQVRAVPARFVPMFSSVAQTAASLAKPGDVVITMGAGDVTLLGGEILDAV 470 >gi|326382560|ref|ZP_08204251.1| UDP-N-acetylmuramate--L-alanine ligase [Gordonia neofelifaecis NRRL B-59395] gi|326198679|gb|EGD55862.1| UDP-N-acetylmuramate--L-alanine ligase [Gordonia neofelifaecis NRRL B-59395] Length=492 Score = 540 bits (1391), Expect = 2e-151, Method: Compositional matrix adjust. Identities = 295/482 (62%), Positives = 347/482 (72%), Gaps = 14/482 (2%) Query 6 LPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDAS 65 LPP L+RVHMVGIGGAGMSG+ARILL RGG VSGSDAK+SRGV ALR RGA +RIGH Sbjct 10 LPPLLQRVHMVGIGGAGMSGLARILLARGGQVSGSDAKDSRGVLALRTRGAQVRIGHSPE 69 Query 66 SLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHG 125 +LD+L GG T VVTT AA+P NPELVEARRRGIPVV RP VLA LM G T++++GTHG Sbjct 70 ALDVLDGGPTVVVTTRAAVPDDNPELVEARRRGIPVVYRPEVLALLMQGDRTVLISGTHG 129 Query 126 KTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHV 185 KT+TTSM +VALQHCG+DPSFAVGGEL E+GTNAHHGSGD FVAEADESDGSLLQYTP + Sbjct 130 KTSTTSMSVVALQHCGVDPSFAVGGELNESGTNAHHGSGDVFVAEADESDGSLLQYTPDI 189 Query 186 AVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRAT----EL 241 V+TNIE+DHLDF+GS AYV VFD FV I GG LV+C DDPG AALA R Sbjct 190 VVVTNIEADHLDFFGSEAAYVQVFDDFVALIRSGGTLVLCLDDPGAAALAARCQADCARR 249 Query 242 GIRVLRYGS-----VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGR 296 G+ VL YGS V G + A L + G G+VA +RL+S L R + +++PGR Sbjct 250 GVTVLGYGSTGHTPVDGVPVVAELAAVVPHGAGSVATVRLSSPLVEKAQTRELAVTLPGR 309 Query 297 HMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHP 356 HMALNALGAL+A + G D V G+ F GV RRFEL G V V+DDYAHHP Sbjct 310 HMALNALGALIACTRTGQDVDAVAAGIESFGGVHRRFELRGRA----RDVDVYDDYAHHP 365 Query 357 TEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAR 416 TE+ A L AAR V+ G GR + VFQPHLYSRT FA +FG AL+ AD+V V DVYGAR Sbjct 366 TEVRAVLTAAREVVAAG-SGRVIAVFQPHLYSRTAEFAPQFGEALSLADDVIVADVYGAR 424 Query 417 EQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILT 476 EQP GV+G +++ V P +VPD S +A VA A GD+++T+GAGD+T+ P IL Sbjct 425 EQPQPGVTGRLISDAVAGPAAFVPDASRIADAVAERARRGDLVLTIGAGDITMQAPAILE 484 Query 477 AL 478 AL Sbjct 485 AL 486 >gi|343924211|ref|ZP_08763774.1| UDP-N-acetylmuramate--L-alanine ligase [Gordonia alkanivorans NBRC 16433] gi|343766016|dbj|GAA10700.1| UDP-N-acetylmuramate--L-alanine ligase [Gordonia alkanivorans NBRC 16433] Length=536 Score = 515 bits (1326), Expect = 8e-144, Method: Compositional matrix adjust. Identities = 296/534 (56%), Positives = 356/534 (67%), Gaps = 47/534 (8%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 V T LPP L RVHMVGIGGAGMSG+ARILL RGG VSGSDAK SRG+ LR RGA +++ Sbjct 7 VGTGGLPPQLARVHMVGIGGAGMSGLARILLARGGQVSGSDAKNSRGILELRTRGARVQV 66 Query 61 GHDASSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMV 120 GHD S+LD +PGG + VVTTHAAIPKTNPELV AR RGIP++LRP VLA+LM G T+++ Sbjct 67 GHDPSALDQIPGGPSVVVTTHAAIPKTNPELVAARSRGIPILLRPRVLAQLMEGDRTMLL 126 Query 121 TGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQ 180 GTHGKT+TTSM +VALQH G DPSFA+GGEL E+GTNAHHG FVAEADESDGSLL+ Sbjct 127 AGTHGKTSTTSMAVVALQHAGSDPSFAIGGELNESGTNAHHGGDPVFVAEADESDGSLLE 186 Query 181 YTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRA-- 238 YTP V +TNI++DHLDF+GS+EAYV VFD F ERI GG LVVC DDPG AALA R Sbjct 187 YTPDVVAVTNIDADHLDFFGSIEAYVDVFDKFTERIRTGGTLVVCLDDPGSAALAGRVRG 246 Query 239 --TELGIRVLRYGS------VPGETMAATLVSWQQQGVGAVAHIRLASELATAQGP---- 286 E G+ VL YG PG ATL+SW+ + G A +R A GP Sbjct 247 DLAERGVAVLGYGRGTHAGLAPGVPNVATLLSWEPRAAGGAARVRFT---APVTGPADET 303 Query 287 -----RVMRLSVPGRHMALNALGALLAAVQIGAPA--------DEVLDGLAGFEGVRRRF 333 R + L +PG HMALNA+ A++ AV++ A D +L G+ F GV RRF Sbjct 304 GTVVERELILPLPGEHMALNAIAAVIGAVRVNAAQTADAAGALDGILAGIGAFGGVHRRF 363 Query 334 ELVGTCGVGKASVRVFDDYAHHPTEISATLAAARMVLEQGDG-----GRCMVVFQPHLYS 388 E G V V DDYAHHPTE+ + L+AA+ ++ G GR + VFQPHLYS Sbjct 364 EFRGRR----GGVEVIDDYAHHPTEVRSVLSAAQAMMAARAGPDAPRGRVIAVFQPHLYS 419 Query 389 RTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQ 448 RT FA EF AL+ AD V V DVYGARE P+ GVSG ++A+ +T P + PD S +A Q Sbjct 420 RTVEFADEFATALDLADTVVVADVYGAREAPIPGVSGRTIADKLTRPSVFAPDLSRLAGQ 479 Query 449 VAAAASPGDVIVTMGAGDVTLLGPEILTAL--------RVRANRSAPGRPGVLG 494 VA A PGD+++T+GAGD+T+ GPEIL AL AN PG G+ G Sbjct 480 VAGLARPGDLVLTLGAGDITMQGPEILAALGADTGTERTTHANGEGPGDGGLTG 533 >gi|334697230|gb|AEG82027.1| UDP-N-acetylmuramate--alanine ligase [Corynebacterium ulcerans 809] Length=485 Score = 490 bits (1262), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 263/479 (55%), Positives = 328/479 (69%), Gaps = 14/479 (2%) Query 9 DLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLD 68 DL RVH++GIGGAGMSG+ARILL RG VSGSDAK+SR V ALR+ GA + +GH A +L Sbjct 9 DLSRVHLIGIGGAGMSGVARILLSRGATVSGSDAKDSRPVLALRSMGAHVAVGHAAENLT 68 Query 69 LLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTT 128 + T VVT+ AAIP+ NPELV AR RGIPV+ R +L +LM G T +++ GTHGKT+ Sbjct 69 IAGEEPTVVVTSFAAIPQDNPELVAARERGIPVIRRSDLLGELMEGSTQVLIAGTHGKTS 128 Query 129 TTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVI 188 TTSM +VA+Q G+DPSFA+GG+L +AGTNAH G+GD FVAEADESD SLL+Y P+VAVI Sbjct 129 TTSMAVVAMQAAGMDPSFAIGGQLNKAGTNAHQGTGDAFVAEADESDASLLRYKPNVAVI 188 Query 189 TNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATEL--GIRVL 246 TNIE DHLDF+ S EAY VF+ F ER+VPGG+LVVC DDP A L Q+ E I+V+ Sbjct 189 TNIEPDHLDFFKSEEAYFEVFEKFAERLVPGGSLVVCLDDPHTAMLGQKVHEEHNDIKVV 248 Query 247 RYGSVPGET----MAATLV-SWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALN 301 YG+ +A T+V S++ G VA I + + L PG+HM LN Sbjct 249 GYGTSAAAADYPDIAKTVVKSFEITHSGTVATIVVEGKEVEVV------LRTPGQHMVLN 302 Query 302 ALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGK-ASVRVFDDYAHHPTEIS 360 A AL A V G ++ G++ F GVRRRFE GT G A + ++DDYAHHPTE++ Sbjct 303 AAAALTAGVIAGGELTKLAAGISDFSGVRRRFEYHGTVAEGDFAGIELYDDYAHHPTEVT 362 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 A L AAR L+ GR +VVFQPHLYSRT F EF AL+ ADE VLD+YGARE+P+ Sbjct 363 AVLTAARSKLQARGQGRLIVVFQPHLYSRTMNFVDEFATALSLADEAIVLDIYGAREKPV 422 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALR 479 GV + E +TVP + PDFS V VA A+PGD+++TMGAG VT+L PEILT LR Sbjct 423 EGVDSRIITEKMTVPAHFEPDFSHVPDAVADVAAPGDLVITMGAGSVTILAPEILTRLR 481 >gi|337291119|ref|YP_004630140.1| UDP-N-acetylmuramate--alanine ligase [Corynebacterium ulcerans BR-AD22] gi|334699425|gb|AEG84221.1| UDP-N-acetylmuramate--alanine ligase [Corynebacterium ulcerans BR-AD22] Length=485 Score = 489 bits (1259), Expect = 5e-136, Method: Compositional matrix adjust. Identities = 262/479 (55%), Positives = 327/479 (69%), Gaps = 14/479 (2%) Query 9 DLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLD 68 DL RVH++GIGGAGMSG+ARILL RG VSGSD K+SR V ALR+ GA + +GH A +L Sbjct 9 DLSRVHLIGIGGAGMSGVARILLSRGATVSGSDVKDSRPVLALRSMGAHVAVGHAAENLT 68 Query 69 LLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTT 128 + T VVT+ AAIP+ NPELV AR RGIPV+ R +L +LM G T +++ GTHGKT+ Sbjct 69 IAGEEPTVVVTSFAAIPQDNPELVAARERGIPVIRRSDLLGELMEGSTQVLIAGTHGKTS 128 Query 129 TTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVI 188 TTSM +VA+Q G+DPSFA+GG+L +AGTNAH G+GD FVAEADESD SLL+Y P+VAVI Sbjct 129 TTSMAVVAMQAAGMDPSFAIGGQLNKAGTNAHQGTGDAFVAEADESDASLLRYKPNVAVI 188 Query 189 TNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATEL--GIRVL 246 TNIE DHLDF+ S EAY VF+ F ER+VPGG+LVVC DDP A L Q+ E I+V+ Sbjct 189 TNIEPDHLDFFKSEEAYFEVFEKFAERLVPGGSLVVCLDDPHTAVLGQKVHEEHNDIKVV 248 Query 247 RYGSVPGET----MAATLV-SWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALN 301 YG+ +A T+V S++ G VA I + + L PG+HM LN Sbjct 249 GYGTSAAAADYPDIAKTVVKSFEITHSGTVATIVVEGKEVEVV------LRTPGQHMVLN 302 Query 302 ALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGK-ASVRVFDDYAHHPTEIS 360 A AL A V G ++ G++ F GVRRRFE GT G A + ++DDYAHHPTE++ Sbjct 303 AAAALTAGVIAGGELTKLAAGISDFSGVRRRFEYHGTVAEGDFAGIELYDDYAHHPTEVT 362 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 A L AAR L+ GR +VVFQPHLYSRT F EF AL+ ADE VLD+YGARE+P+ Sbjct 363 AVLTAARSKLQARGQGRLIVVFQPHLYSRTMNFVDEFATALSLADEAIVLDIYGAREKPV 422 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALR 479 GV + E +TVP + PDFS V VA A+PGD+++TMGAG VT+L PEILT LR Sbjct 423 EGVDSRIITEKMTVPAHFEPDFSHVPDAVADVAAPGDLVITMGAGSVTILAPEILTRLR 481 >gi|302206518|gb|ADL10860.1| UDP-N-acetyl muramate--L-alanine ligase [Corynebacterium pseudotuberculosis C231] gi|308276760|gb|ADO26659.1| UDP-N-acetyl muramate--L-alanine ligase [Corynebacterium pseudotuberculosis I19] gi|341825200|gb|AEK92721.1| UDP-N-acetyl muramate--L-alanine ligase [Corynebacterium pseudotuberculosis PAT10] Length=485 Score = 483 bits (1244), Expect = 3e-134, Method: Compositional matrix adjust. Identities = 259/479 (55%), Positives = 328/479 (69%), Gaps = 14/479 (2%) Query 9 DLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLD 68 DL RVH++GIGGAGMSG+ARILL RG VSGSD K+SR V ALR+ GA + +GH A +L Sbjct 9 DLSRVHLIGIGGAGMSGVARILLSRGATVSGSDVKDSRAVLALRSMGAHVAVGHAAENLS 68 Query 69 LLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTT 128 + T VVT+ AAIP+ NPELV AR GIPV+ R +L +LM G T +++ GTHGKT+ Sbjct 69 IAGEKPTVVVTSFAAIPQDNPELVAARELGIPVIRRSDLLGELMEGSTQVLIAGTHGKTS 128 Query 129 TTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVI 188 TTSM +VA+Q G+DPSFA+GG+L +AGTNAH G+GD FVAEADESD SLL+Y P++AVI Sbjct 129 TTSMAVVAMQAAGMDPSFAIGGQLNKAGTNAHQGTGDAFVAEADESDASLLRYKPNIAVI 188 Query 189 TNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE--LGIRVL 246 TNIE DHLDF+ S EAY VF+ F +R+VPG +LVVC DDP A L Q+ E I+V+ Sbjct 189 TNIEPDHLDFFKSEEAYFEVFEKFADRLVPGVSLVVCLDDPHTAMLGQKIHEKHKDIKVV 248 Query 247 RYGSVPGET----MAATLV-SWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALN 301 YG+V +A T+V S++ G VA I + Q V+ L PGRHM LN Sbjct 249 GYGTVAASAEYPDIAKTVVESFEITHSGTVATI-----VVGGQETEVV-LRTPGRHMVLN 302 Query 302 ALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGK-ASVRVFDDYAHHPTEIS 360 A AL A V G ++ G++ F GVRRRFE G G A + ++DDYAHHPTE+S Sbjct 303 AAAALTAGVIAGGDLFKLAAGISDFSGVRRRFEYHGVVAEGDFAGIELYDDYAHHPTEVS 362 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 A L AAR L+ GR +V+FQPHLYSRT F EF AL+ ADE VLD+YGARE+P+ Sbjct 363 AVLTAARAKLQARGQGRLLVIFQPHLYSRTINFVDEFAAALSLADEAIVLDIYGAREKPV 422 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALR 479 GV + + +T+P + PDFS V + VA A+PGD+++TMGAG VT+L PEILT LR Sbjct 423 EGVDSRIITDKMTIPAHFEPDFSHVPEAVADLAAPGDLVITMGAGSVTILAPEILTRLR 481 >gi|344044827|gb|EGV40502.1| UDP-N-acetylmuramate--L-alanine ligase [Corynebacterium glutamicum S9114] Length=486 Score = 483 bits (1243), Expect = 3e-134, Method: Compositional matrix adjust. Identities = 247/478 (52%), Positives = 327/478 (69%), Gaps = 13/478 (2%) Query 9 DLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLD 68 DL RVH++GIGGAGMSG+ARILL RG V+GSDAK+SR + LRA GA I +GH A +L+ Sbjct 13 DLSRVHLIGIGGAGMSGVARILLARGKTVTGSDAKDSRTLLPLRAVGATIAVGHAAENLE 72 Query 69 LLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTT 128 L T VVT+ AAIP+ NPELV AR GIPV+ R +L +L+ G T +++ GTHGKT+ Sbjct 73 LSGELPTVVVTSFAAIPQDNPELVRAREEGIPVIRRSDLLGELLEGSTQVLIAGTHGKTS 132 Query 129 TTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVI 188 TTSM +VA+Q G+DPSFA+GG+L +AGTNAHHG+G+ F+AEADESD SLL+Y P+VAV+ Sbjct 133 TTSMSVVAMQAAGMDPSFAIGGQLNKAGTNAHHGTGEVFIAEADESDASLLRYKPNVAVV 192 Query 189 TNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRY 248 TN+E DHLDF+ + EAY VFD F RI P G LVVC +DP A L +R+ GI+ + Y Sbjct 193 TNVEPDHLDFFKTPEAYFQVFDDFAGRITPNGKLVVCLNDPHAAELGERSVRKGIKTVGY 252 Query 249 GSV------PGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNA 302 G+ P AT+V Q G A I + + + + L +PG HM LN Sbjct 253 GTADAVQAHPEVPAMATIVDSQVVAEGTRATINIDGQEVS------VILQIPGDHMVLNG 306 Query 303 LGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKAS-VRVFDDYAHHPTEISA 361 ALLA +G D++++GL+ F GVRRRFE G GK + ++DDYAHHPTE++A Sbjct 307 AAALLAGYLVGGDVDKLVEGLSDFSGVRRRFEFHGAIEGGKFNGAAIYDDYAHHPTEVTA 366 Query 362 TLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLA 421 L+AAR +++ GR +V FQPHLYSRT F EF AL+ AD VL++YGAREQP+ Sbjct 367 VLSAARTLVKAAGKGRVIVAFQPHLYSRTMEFQKEFAEALSLADAAVVLEIYGAREQPVD 426 Query 422 GVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALR 479 GVS + + +T+P+ Y P+FSAV +++A A P D+++TMGAG VT+L PEIL L+ Sbjct 427 GVSSEIITDAMTIPVVYEPNFSAVPERIAEIAGPNDIVLTMGAGSVTMLAPEILDQLQ 484 >gi|172040884|ref|YP_001800598.1| UDP-N-acetylmuramate--L-alanine ligase [Corynebacterium urealyticum DSM 7109] gi|229486485|sp|B1VHC3.1|MURC_CORU7 RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|171852188|emb|CAQ05164.1| UDP-N-acetylmuramate--alanine ligase [Corynebacterium urealyticum DSM 7109] Length=487 Score = 482 bits (1241), Expect = 5e-134, Method: Compositional matrix adjust. Identities = 271/502 (54%), Positives = 335/502 (67%), Gaps = 28/502 (5%) Query 1 VSTEQLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRI 60 ++T+ DL R HMVGIGGAGMSGIARILL RG V+GSD K+SR V ALRA GA + I Sbjct 1 MTTQPEQIDLSRTHMVGIGGAGMSGIARILLARGYSVTGSDMKDSRSVLALRAAGAEVAI 60 Query 61 GHDASSLDLLPGGA---TAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTT 117 GHDA+++ GGA T VVT+ AAIPK NPEL AR GIP+V R VLA+LM+ R Sbjct 61 GHDAANV---TGGAELPTVVVTSFAAIPKDNPELTAAREAGIPIVRRSDVLAELMSDRRA 117 Query 118 LMVTGTHGKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGS 177 ++ GTHGKT+TTSM +V +Q GLDPSFA+GG+L AGTNAHHG+G+ F+AEADESDGS Sbjct 118 FLLAGTHGKTSTTSMAVVGVQAAGLDPSFAIGGQLNRAGTNAHHGTGEIFIAEADESDGS 177 Query 178 LLQYTPHVAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQR 237 L Y+P VAVITNIE DHLD+YG+ EAYVA+FD F ++ PGG LV C DDPG AALA R Sbjct 178 FLSYSPEVAVITNIEPDHLDYYGTEEAYVAIFDEFATKVTPGGYLVCCLDDPGAAALAAR 237 Query 238 ATELGI--RVLRYGSV------PGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRV- 288 G VL YGS P AA + G A +R Q R Sbjct 238 VRAAGTAPTVLGYGSRAAADQHPDIPAAAIIEEMIPDARGTAAKVRFN---LPGQEERYE 294 Query 289 -MRLSVPGRHMALNALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVR 347 +R+++PG HM LN + A+ +GA ++V+ G+A F+GVRRRFE G G VR Sbjct 295 DIRVAIPGAHMTLNGVAAITGGALLGADLEKVIAGVADFDGVRRRFEYHGEAG----GVR 350 Query 348 VFDDYAHHPTEISATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEV 407 V+DDYAHHPTE++A L AA+ ++E D GR + VFQPHLYSRT FA+EF RAL+ ADEV Sbjct 351 VYDDYAHHPTEVTAVLTAAKELVEATDAGRIIAVFQPHLYSRTMNFASEFARALSLADEV 410 Query 408 FVLDVYGAREQPLAGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDV 467 +LD++GAREQP+ GV + E +T + PDFSAVA+QV A PGDV++T+GAG V Sbjct 411 VLLDIFGAREQPVEGVDSRIIGEKLTCEWHFQPDFSAVAEQVIGIAKPGDVVLTIGAGTV 470 Query 468 TLLGPEILTALRVRANRSAPGR 489 T+L EIL R R A G Sbjct 471 TMLADEIL-----RCGREAQGE 487 >gi|256379761|ref|YP_003103421.1| UDP-N-acetylmuramate--L-alanine ligase [Actinosynnema mirum DSM 43827] gi|255924064|gb|ACU39575.1| UDP-N-acetylmuramate/alanine ligase [Actinosynnema mirum DSM 43827] Length=466 Score = 482 bits (1241), Expect = 5e-134, Method: Compositional matrix adjust. Identities = 286/475 (61%), Positives = 337/475 (71%), Gaps = 17/475 (3%) Query 10 LRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLDL 69 L RVH+VGIGGAGMSGIARILL RG VSGSDAK+SR V ALRA+GA + +GHD ++LD Sbjct 5 LDRVHLVGIGGAGMSGIARILLARGAEVSGSDAKDSRTVLALRAQGAHVAVGHDGANLDQ 64 Query 70 LPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTTT 129 L GG TAVV + AI + NPELV AR RG+ V+ R LA LM V GTHGKT+T Sbjct 65 LDGGPTAVVVS-TAIREDNPELVAARERGVAVLRRAEALAALMLDHRVACVAGTHGKTST 123 Query 130 TSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVIT 189 TSML VALQHC +DPSFA+GG+L E+G NAH G+G FVAEADESDGS L + P VAV+T Sbjct 124 TSMLTVALQHCRMDPSFAIGGDLNESGANAHQGAGGVFVAEADESDGSFLFFAPSVAVVT 183 Query 190 NIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRYG 249 N+E+DHLD +G+VEAYVAVFD F+ERI PGG L+ C DD G AALA RA + GIRV RYG Sbjct 184 NVEADHLDHHGTVEAYVAVFDEFLERIEPGGVLIACADDEGSAALADRAEKRGIRVRRYG 243 Query 250 SVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALGALLAA 309 AA LV + G G +A + L E +R++VPG HMA NA+ ALLAA Sbjct 244 RAATGEGAAVLVEHRPDGAGGLAVVELDGERLD------VRVAVPGEHMAGNAVAALLAA 297 Query 310 VQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLAAARMV 369 V++GA VL+GLA F GVRRRFE G A VRV+DDYAHHPTE++A L AAR V Sbjct 298 VELGADRWGVLEGLAAFGGVRRRFEFKGVA----AGVRVYDDYAHHPTEVAAQLKAARPV 353 Query 370 LEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVSGASVA 429 GD GR +VVFQPHLYSRTK FAAEFG+AL ADEV VLDVYGARE P GV+G VA Sbjct 354 --AGD-GRLVVVFQPHLYSRTKTFAAEFGKALALADEVVVLDVYGAREDPEPGVTGELVA 410 Query 430 EHVTVP---MRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVR 481 + V + +R+VP F V + VA GD++VTMGAGDVT+LGP I+ AL R Sbjct 411 DAVPLEAGRVRHVPSFDRVPELVAGLVREGDLVVTMGAGDVTMLGPVIVDALAHR 465 >gi|145296119|ref|YP_001138940.1| UDP-N-acetylmuramate--L-alanine ligase [Corynebacterium glutamicum R] gi|166224333|sp|A4QFM2.1|MURC_CORGB RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase gi|3868935|dbj|BAA34293.1| MurC [Corynebacterium glutamicum] gi|140846039|dbj|BAF55038.1| hypothetical protein [Corynebacterium glutamicum R] Length=486 Score = 482 bits (1241), Expect = 6e-134, Method: Compositional matrix adjust. Identities = 247/478 (52%), Positives = 326/478 (69%), Gaps = 13/478 (2%) Query 9 DLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLD 68 DL RVH++GIGGAGMSG+ARILL RG V+GSDAK+SR + LRA GA I +GH A +L+ Sbjct 13 DLSRVHLIGIGGAGMSGVARILLARGKTVTGSDAKDSRTLLPLRAVGATIAVGHAAENLE 72 Query 69 LLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTT 128 L T VVT+ AAIP+ NPELV AR GIPV+ R +L +L+ G T +++ GTHGKT+ Sbjct 73 LSGELPTVVVTSFAAIPQDNPELVRAREEGIPVIRRSDLLGELLEGSTQVLIAGTHGKTS 132 Query 129 TTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVI 188 TTSM +VA+Q G+DPSFA+GG+L +AGTNAHHG+G+ F+AEADESD SLL+Y P+VAV+ Sbjct 133 TTSMSVVAMQAAGMDPSFAIGGQLNKAGTNAHHGTGEVFIAEADESDASLLRYKPNVAVV 192 Query 189 TNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRY 248 TN+E DHLDF+ + EAY VFD F RI P G LVVC +DP A L +R+ GI+ + Y Sbjct 193 TNVEPDHLDFFKTPEAYFQVFDDFAGRITPNGKLVVCLNDPHAAELGERSVRKGIKTVGY 252 Query 249 GSV------PGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNA 302 G+ P AT+V Q G A I + + + + L +PG HM LN Sbjct 253 GTADAVQAHPEVPAMATIVDSQVVAEGTRATINIDGQEVS------VILQIPGDHMVLNG 306 Query 303 LGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKAS-VRVFDDYAHHPTEISA 361 ALLA +G D++++GL+ F GVRRRFE G GK + ++DDYAHHPTE++A Sbjct 307 AAALLAGYLVGGDVDKLVEGLSDFSGVRRRFEFHGAIEGGKFNGAAIYDDYAHHPTEVTA 366 Query 362 TLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLA 421 L+AAR ++ GR +V FQPHLYSRT F EF AL+ AD VL++YGAREQP+ Sbjct 367 VLSAARTRVKAAGKGRVIVAFQPHLYSRTMEFQKEFAEALSLADAAVVLEIYGAREQPVD 426 Query 422 GVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALR 479 GVS + + +T+P+ Y P+FSAV +++A A P D+++TMGAG VT+L PEIL L+ Sbjct 427 GVSSEIITDAMTIPVVYEPNFSAVPERIAEIAGPNDIVLTMGAGSVTMLAPEILDQLQ 484 >gi|300858813|ref|YP_003783796.1| UDP-N-acetylmuramate--alanine ligase [Corynebacterium pseudotuberculosis FRC41] gi|300686267|gb|ADK29189.1| UDP-N-acetylmuramate--alanine ligase [Corynebacterium pseudotuberculosis FRC41] gi|302331073|gb|ADL21267.1| UDP-N-acetyl muramate--L-alanine ligase [Corynebacterium pseudotuberculosis 1002] Length=485 Score = 482 bits (1240), Expect = 8e-134, Method: Compositional matrix adjust. Identities = 259/479 (55%), Positives = 327/479 (69%), Gaps = 14/479 (2%) Query 9 DLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLD 68 DL RVH++GIGGAGMSG+ARILL RG VSGSD K+SR V ALR GA + +GH A +L Sbjct 9 DLSRVHLIGIGGAGMSGVARILLSRGATVSGSDVKDSRAVLALRFMGAHVAVGHAAENLS 68 Query 69 LLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTT 128 + T VVT+ AAIP+ NPELV AR GIPV+ R +L +LM G T +++ GTHGKT+ Sbjct 69 IAGEKPTVVVTSFAAIPQDNPELVAARELGIPVIRRSDLLGELMEGSTQVLIAGTHGKTS 128 Query 129 TTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVI 188 TTSM +VA+Q G+DPSFA+GG+L +AGTNAH G+GD FVAEADESD SLL+Y P++AVI Sbjct 129 TTSMAVVAMQAAGMDPSFAIGGQLNKAGTNAHQGTGDAFVAEADESDASLLRYKPNIAVI 188 Query 189 TNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATE--LGIRVL 246 TNIE DHLDF+ S EAY VF+ F +R+VPG +LVVC DDP A L Q+ E I+V+ Sbjct 189 TNIEPDHLDFFKSEEAYFEVFEKFADRLVPGVSLVVCLDDPHTAMLGQKIHEKHKDIKVV 248 Query 247 RYGSVPGET----MAATLV-SWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALN 301 YG+V +A T+V S++ G VA I + Q V+ L PGRHM LN Sbjct 249 GYGTVAASAEYPDIAKTVVESFEITHSGTVATI-----VVGGQETEVV-LRTPGRHMVLN 302 Query 302 ALGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGK-ASVRVFDDYAHHPTEIS 360 A AL A V G ++ G++ F GVRRRFE G G A + ++DDYAHHPTE+S Sbjct 303 AAAALTAGVIAGGDLFKLAAGISDFSGVRRRFEYHGVVAEGDFAGIELYDDYAHHPTEVS 362 Query 361 ATLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPL 420 A L AAR L+ GR +V+FQPHLYSRT F EF AL+ ADE VLD+YGARE+P+ Sbjct 363 AVLTAARAKLQARGQGRLLVIFQPHLYSRTINFVDEFAAALSLADEAIVLDIYGAREKPV 422 Query 421 AGVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALR 479 GV + + +T+P + PDFS V + VA A+PGD+++TMGAG VT+L PEILT LR Sbjct 423 EGVDSRIITDKMTIPAHFEPDFSHVPEAVADLAAPGDLVITMGAGSVTILAPEILTRLR 481 >gi|29337227|sp|P94335.5|MURC_CORGL RecName: Full=UDP-N-acetylmuramate--L-alanine ligase; AltName: Full=UDP-N-acetylmuramoyl-L-alanine synthetase Length=486 Score = 481 bits (1239), Expect = 9e-134, Method: Compositional matrix adjust. Identities = 247/478 (52%), Positives = 326/478 (69%), Gaps = 13/478 (2%) Query 9 DLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLD 68 DL RVH++GIGGAGMSG+ARILL RG V+GSDAK+SR + LRA GA I +GH A +L+ Sbjct 13 DLSRVHLIGIGGAGMSGVARILLARGKTVTGSDAKDSRTLLPLRAVGATIAVGHAAENLE 72 Query 69 LLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTT 128 L T VVT+ AAIP+ NPELV AR GIPV+ R +L +L+ G T +++ GTHGKT+ Sbjct 73 LSGELPTVVVTSFAAIPQDNPELVRAREEGIPVIRRSDLLGELLEGSTQVLIAGTHGKTS 132 Query 129 TTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVI 188 TTSM +VA+Q G+DPSFA+GG+L +AGTNAHHG+G+ F+AEADESD SLL+Y P+VAV+ Sbjct 133 TTSMSVVAMQAAGMDPSFAIGGQLNKAGTNAHHGTGEVFIAEADESDASLLRYKPNVAVV 192 Query 189 TNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRY 248 TN+E DHLDF+ + EAY VFD F RI P G LVVC +DP A L +R+ GI+ + Y Sbjct 193 TNVEPDHLDFFKTPEAYFQVFDDFAGRITPNGKLVVCLNDPHAAELGERSVRKGIKTVGY 252 Query 249 GSV------PGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNA 302 G+ P AT+V Q G A I + + + + L +PG HM LN Sbjct 253 GTADAVQAHPEVPAMATIVDSQVVAEGTRATINIDGQEVS------VILQIPGDHMVLNG 306 Query 303 LGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKAS-VRVFDDYAHHPTEISA 361 ALLA +G D++++GL+ F GVRRRFE G GK + ++DDYAHHPTE++A Sbjct 307 AAALLAGYLVGGDVDKLVEGLSDFSGVRRRFEFHGAIEGGKFNGAAIYDDYAHHPTEVTA 366 Query 362 TLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLA 421 L+AAR ++ GR +V FQPHLYSRT F EF AL+ AD VL++YGAREQP+ Sbjct 367 VLSAARTRVKAAGKGRVIVAFQPHLYSRTIEFQKEFAEALSLADAAVVLEIYGAREQPVD 426 Query 422 GVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALR 479 GVS + + +T+P+ Y P+FSAV +++A A P D+++TMGAG VT+L PEIL L+ Sbjct 427 GVSSEIITDAMTIPVVYEPNFSAVPERIAEIAGPNDIVLTMGAGSVTMLAPEILDQLQ 484 >gi|300788096|ref|YP_003768387.1| UDP-N-acetylmuramate--alanine ligase [Amycolatopsis mediterranei U32] gi|299797610|gb|ADJ47985.1| UDP-N-acetylmuramate--alanine ligase [Amycolatopsis mediterranei U32] gi|340529680|gb|AEK44885.1| UDP-N-acetylmuramate--L-alanine ligase [Amycolatopsis mediterranei S699] Length=465 Score = 480 bits (1236), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 267/477 (56%), Positives = 326/477 (69%), Gaps = 14/477 (2%) Query 5 QLPPDLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDA 64 +LP +LRR H++GIGGAGMSGIARILL RG VSGSDAKESR + +LRA+GA + +G A Sbjct 3 ELPEELRRAHLIGIGGAGMSGIARILLARGAFVSGSDAKESRALLSLRAQGAELFVGQSA 62 Query 65 SSLDLLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTH 124 +++ L +AVV + AI +TNPEL AR GIPV+ R LA LM G + GTH Sbjct 63 ANISSLAEPPSAVVVS-TAIKETNPELAAARAAGIPVLHRAQALAGLMEGHRVACIAGTH 121 Query 125 GKTTTTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPH 184 GKT+TTSML VALQHC LDPSFA+GG+L E+G NAHHG G FVAEADESDGS L Y+P Sbjct 122 GKTSTTSMLTVALQHCRLDPSFAIGGDLNESGANAHHGEGGVFVAEADESDGSFLTYSPS 181 Query 185 VAVITNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIR 244 VAV+TN+E DHLD +G+ EAY VF FV RIVPGG L+VC DDP L ++A +LG+R Sbjct 182 VAVVTNVEPDHLDHHGTAEAYTKVFTEFVSRIVPGGLLIVCGDDPAADDLGRQAEDLGVR 241 Query 245 VLRYGSVPGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNALG 304 V RYG A ++ + G V + L E + +R++VPG HMALNA+ Sbjct 242 VRRYGRTATGPGDARILEYVPAPDGGVVRLVLDGEEVS------VRVAVPGEHMALNAIA 295 Query 305 ALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKASVRVFDDYAHHPTEISATLA 364 ALLA +++GAP ++DGLA F GVRRRFE G G VRV+DDYAHHPTE++A L Sbjct 296 ALLAGIELGAPVPGLVDGLAAFGGVRRRFEFKGRAG----DVRVYDDYAHHPTEVAAQLR 351 Query 365 AARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLAGVS 424 A R GR +VVFQPHLYSRTK F+ EF AL+ ADEV VLDVYGARE+P G++ Sbjct 352 AVRTA---AGSGRVIVVFQPHLYSRTKTFSVEFAEALSLADEVVVLDVYGAREEPEPGIT 408 Query 425 GASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALRVR 481 GA +A+ VT + Y P F A A A PGD++VTMGAGDVT LGPEIL L R Sbjct 409 GALIADRVTAAVHYEPAFDVAAPLAAGLAKPGDLVVTMGAGDVTQLGPEILAELDKR 465 >gi|19553357|ref|NP_601359.1| UDP-N-acetylmuramate--L-alanine ligase [Corynebacterium glutamicum ATCC 13032] gi|62390996|ref|YP_226398.1| UDP-N-acetylmuramate--L-alanine ligase [Corynebacterium glutamicum ATCC 13032] gi|21324927|dbj|BAB99550.1| UDP-N-acetylmuramate-alanine ligase [Corynebacterium glutamicum ATCC 13032] gi|41326335|emb|CAF20497.1| PROBABLE UDP-N-ACETYLMURAMATE--ALANINE LIGASE PROTEIN [Corynebacterium glutamicum ATCC 13032] Length=486 Score = 480 bits (1236), Expect = 2e-133, Method: Compositional matrix adjust. Identities = 247/478 (52%), Positives = 326/478 (69%), Gaps = 13/478 (2%) Query 9 DLRRVHMVGIGGAGMSGIARILLDRGGLVSGSDAKESRGVHALRARGALIRIGHDASSLD 68 DL RVH++GIGGAGMSG+ARILL RG V+GSDAK+SR + LRA GA I +GH A +L+ Sbjct 13 DLSRVHLIGIGGAGMSGVARILLARGKTVTGSDAKDSRTLLPLRAVGATIAVGHAAENLE 72 Query 69 LLPGGATAVVTTHAAIPKTNPELVEARRRGIPVVLRPAVLAKLMAGRTTLMVTGTHGKTT 128 L T VVT+ AAIP+ NPELV AR GIPV+ R +L +L+ G T +++ GTHGKT+ Sbjct 73 LSGELPTVVVTSFAAIPQDNPELVRAREEGIPVIRRSDLLGELLEGSTQVLIAGTHGKTS 132 Query 129 TTSMLIVALQHCGLDPSFAVGGELGEAGTNAHHGSGDCFVAEADESDGSLLQYTPHVAVI 188 TTSM +VA+Q G+DPSFA+GG+L +AGTNAHHG+G+ F+AEADESD SLL+Y P+VAV+ Sbjct 133 TTSMSVVAMQAAGMDPSFAIGGQLNKAGTNAHHGTGEVFIAEADESDASLLRYKPNVAVV 192 Query 189 TNIESDHLDFYGSVEAYVAVFDSFVERIVPGGALVVCTDDPGGAALAQRATELGIRVLRY 248 TN+E DHLDF+ + EAY VFD F RI P G LVVC +DP A L +R+ GI+ + Y Sbjct 193 TNVEPDHLDFFKTPEAYFQVFDDFAGRITPNGKLVVCLNDPHAAELGERSVRKGIKTVGY 252 Query 249 GSV------PGETMAATLVSWQQQGVGAVAHIRLASELATAQGPRVMRLSVPGRHMALNA 302 G+ P AT+V Q G A I + + + + L +PG HM LN Sbjct 253 GTADAVQAHPEVPAMATIVDSQVVAEGTRATINIDGQEVS------VILQIPGDHMVLNG 306 Query 303 LGALLAAVQIGAPADEVLDGLAGFEGVRRRFELVGTCGVGKAS-VRVFDDYAHHPTEISA 361 ALLA +G D++++GL+ F GVRRRFE G GK + ++DDYAHHPTE++A Sbjct 307 AAALLAGYLVGGDVDKLVEGLSDFSGVRRRFEFHGAIEGGKFNGAAIYDDYAHHPTEVTA 366 Query 362 TLAAARMVLEQGDGGRCMVVFQPHLYSRTKAFAAEFGRALNAADEVFVLDVYGAREQPLA 421 L+AAR ++ GR +V FQPHLYSRT F EF AL+ AD VL++YGAREQP+ Sbjct 367 VLSAARTRVKAAGKGRVIVAFQPHLYSRTIEFQKEFAGALSLADAAVVLEIYGAREQPVD 426 Query 422 GVSGASVAEHVTVPMRYVPDFSAVAQQVAAAASPGDVIVTMGAGDVTLLGPEILTALR 479 GVS + + +T+P+ Y P+FSAV +++A A P D+++TMGAG VT+L PEIL L+ Sbjct 427 GVSSEIITDAMTIPVVYEPNFSAVPERIAEIAGPNDIVLTMGAGSVTMLAPEILDQLQ 484 Lambda K H 0.320 0.135 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1059382658600 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40