BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2155c Length=486 Score E Sequences producing significant alignments: (Bits) Value gi|308232050|ref|ZP_07663984.1| UDP-N-acetylmuramoylalanine-D-gl... 936 0.0 gi|148661971|ref|YP_001283494.1| UDP-N-acetylmuramoyl-L-alanyl-D... 936 0.0 gi|253798780|ref|YP_003031781.1| UDP-N-acetylmuramoylalanine-D-g... 933 0.0 gi|31793335|ref|NP_855828.1| UDP-N-acetylmuramoyl-L-alanyl-D-glu... 932 0.0 gi|323719310|gb|EGB28452.1| UDP-N-acetylmuramoylalanine-D-glutam... 931 0.0 gi|308369635|ref|ZP_07666766.1| UDP-N-acetylmuramoylalanine-D-gl... 931 0.0 gi|15841647|ref|NP_336684.1| UDP-N-acetylmuramoyl-L-alanyl-D-glu... 930 0.0 gi|340627163|ref|YP_004745615.1| putative UDP-N-acetylmuramoylal... 930 0.0 gi|339632187|ref|YP_004723829.1| UDP-N-acetylmuramoylalanine-D-g... 929 0.0 gi|339295071|gb|AEJ47182.1| UDP-N-acetylmuramoyl-L-alanyl-D-glut... 902 0.0 gi|289447783|ref|ZP_06437527.1| UDP-N-acetylMuramoylalanine-D-gl... 815 0.0 gi|289750752|ref|ZP_06510130.1| UDP-N-acetylmuramoylalanine-D-gl... 778 0.0 gi|240168219|ref|ZP_04746878.1| UDP-N-acetylmuramoyl-L-alanyl-D-... 680 0.0 gi|15827432|ref|NP_301695.1| UDP-N-acetylmuramoyl-L-alanyl-D-glu... 645 0.0 gi|183983185|ref|YP_001851476.1| UDP-N-acetylmuramoylalanine-D-g... 644 0.0 gi|118618797|ref|YP_907129.1| UDP-N-acetylmuramoyl-L-alanyl-D-gl... 635 5e-180 gi|336461945|gb|EGO40797.1| UDP-N-acetylmuramoylalanine--D-gluta... 632 3e-179 gi|289570272|ref|ZP_06450499.1| UDP-N-acetylmuramoylalanine-D-gl... 631 7e-179 gi|41407997|ref|NP_960833.1| UDP-N-acetylmuramoyl-L-alanyl-D-glu... 631 9e-179 gi|118463229|ref|YP_881538.1| UDP-N-acetylmuramoyl-L-alanyl-D-gl... 630 2e-178 gi|254775006|ref|ZP_05216522.1| UDP-N-acetylmuramoyl-L-alanyl-D-... 627 2e-177 gi|296166023|ref|ZP_06848474.1| UDP-N-acetylmuramoyl-L-alanine-D... 620 2e-175 gi|342859871|ref|ZP_08716524.1| UDP-N-acetylmuramoyl-L-alanyl-D-... 611 7e-173 gi|333990381|ref|YP_004522995.1| UDP-N-acetylmuramoylalanine-D-g... 554 1e-155 gi|289745329|ref|ZP_06504707.1| UDP-N-acetylmuramoylalanine-D-gl... 533 2e-149 gi|145223573|ref|YP_001134251.1| UDP-N-acetylmuramoyl-L-alanyl-D... 524 2e-146 gi|289762316|ref|ZP_06521694.1| UDP-N-acetylmuramoylalanine-D-gl... 514 1e-143 gi|118470144|ref|YP_888506.1| UDP-N-acetylmuramoyl-L-alanyl-D-gl... 514 1e-143 gi|126435847|ref|YP_001071538.1| UDP-N-acetylmuramoyl-L-alanyl-D... 506 5e-141 gi|108800224|ref|YP_640421.1| UDP-N-acetylmuramoyl-L-alanyl-D-gl... 504 1e-140 gi|120404497|ref|YP_954326.1| UDP-N-acetylmuramoyl-L-alanyl-D-gl... 493 4e-137 gi|169629091|ref|YP_001702740.1| UDP-N-acetylmuramoyl-L-alanyl-D... 454 2e-125 gi|111018103|ref|YP_701075.1| UDP-N-acetylmuramoyl-L-alanyl-D-gl... 411 1e-112 gi|312140144|ref|YP_004007480.1| UDP-N-acetylmuramoyl-l-alanine-... 400 2e-109 gi|226307041|ref|YP_002767001.1| UDP-N-acetylmuramoylalanine--D-... 399 5e-109 gi|325676975|ref|ZP_08156647.1| UDP-N-acetylmuramoyl-L-alanine-D... 399 9e-109 gi|229490474|ref|ZP_04384315.1| UDP-N-acetylmuramoylalanine--D-g... 397 2e-108 gi|226360232|ref|YP_002778010.1| UDP-N-acetylmuramoyl-L-alanyl-D... 397 2e-108 gi|296140344|ref|YP_003647587.1| UDP-N-acetylmuramoylalanine/D-g... 384 2e-104 gi|118595670|sp|Q5YYY1.2|MURD_NOCFA RecName: Full=UDP-N-acetylmu... 363 5e-98 gi|54023732|ref|YP_117974.1| UDP-N-acetylmuramoyl-L-alanyl-D-glu... 362 6e-98 gi|291003737|ref|ZP_06561710.1| UDP-N-acetylmuramoylalanine--D-g... 354 2e-95 gi|333918996|ref|YP_004492577.1| UDP-N-acetylmuramoylalanine--D-... 353 3e-95 gi|134102301|ref|YP_001107962.1| UDP-N-acetylmuramoylalanine--D-... 353 4e-95 gi|257056719|ref|YP_003134551.1| UDP-N-acetylmuramoylalanine--D-... 347 2e-93 gi|29832662|ref|NP_827296.1| UDP-N-acetylmuramoyl-L-alanyl-D-glu... 347 2e-93 gi|21220566|ref|NP_626345.1| UDP-N-acetylmuramoyl-L-alanyl-D-glu... 343 5e-92 gi|302518529|ref|ZP_07270871.1| UDP-N-acetylmuramoylalanine-D-gl... 342 6e-92 gi|318057552|ref|ZP_07976275.1| UDP-N-acetylmuramoyl-L-alanyl-D-... 340 3e-91 gi|262202912|ref|YP_003274120.1| UDP-N-acetylmuramoylalanine/D-g... 340 3e-91 >gi|308232050|ref|ZP_07663984.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis SUMu001] gi|308379132|ref|ZP_07485179.2| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis SUMu010] gi|308380283|ref|ZP_07489396.2| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis SUMu011] 6 more sequence titles Length=489 Score = 936 bits (2420), Expect = 0.0, Method: Compositional matrix adjust. Identities = 486/486 (100%), Positives = 486/486 (100%), Gaps = 0/486 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 4 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 63 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 64 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 123 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 124 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 183 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 184 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 243 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 244 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 303 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 304 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 363 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV Sbjct 364 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 423 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA Sbjct 424 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 483 Query 481 VRAVIR 486 VRAVIR Sbjct 484 VRAVIR 489 >gi|148661971|ref|YP_001283494.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium tuberculosis H37Ra] gi|167966739|ref|ZP_02549016.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium tuberculosis H37Ra] gi|3122403|sp|O06222.1|MURD_MYCTU RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|158513374|sp|A5U4I2.1|MURD_MYCTA RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|2104323|emb|CAB08672.1| Probable UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis H37Rv] gi|148506123|gb|ABQ73932.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis H37Ra] Length=486 Score = 936 bits (2418), Expect = 0.0, Method: Compositional matrix adjust. Identities = 485/486 (99%), Positives = 486/486 (100%), Gaps = 0/486 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 +LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 1 MLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV Sbjct 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA Sbjct 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 Query 481 VRAVIR 486 VRAVIR Sbjct 481 VRAVIR 486 >gi|253798780|ref|YP_003031781.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis KZN 1435] gi|289554058|ref|ZP_06443268.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis KZN 605] gi|253320283|gb|ACT24886.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis KZN 1435] gi|289438690|gb|EFD21183.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis KZN 605] gi|328458543|gb|AEB03966.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis KZN 4207] Length=489 Score = 933 bits (2411), Expect = 0.0, Method: Compositional matrix adjust. Identities = 485/486 (99%), Positives = 485/486 (99%), Gaps = 0/486 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 4 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 63 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 64 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 123 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 124 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 183 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 184 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 243 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 244 LGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 303 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 304 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 363 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV Sbjct 364 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 423 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA Sbjct 424 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 483 Query 481 VRAVIR 486 VRAVIR Sbjct 484 VRAVIR 489 >gi|31793335|ref|NP_855828.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium bovis AF2122/97] gi|121638037|ref|YP_978261.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|148823364|ref|YP_001288118.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium tuberculosis F11] 26 more sequence titles Length=486 Score = 932 bits (2410), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/486 (99%), Positives = 485/486 (99%), Gaps = 0/486 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 +LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 1 MLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 241 LGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV Sbjct 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA Sbjct 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 Query 481 VRAVIR 486 VRAVIR Sbjct 481 VRAVIR 486 >gi|323719310|gb|EGB28452.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase [Mycobacterium tuberculosis CDC1551A] Length=489 Score = 931 bits (2405), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/486 (99%), Positives = 484/486 (99%), Gaps = 0/486 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 4 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 63 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPGFSPA PLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 64 VQQITGYALVVASPGFSPAIPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 123 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 124 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 183 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 184 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 243 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 244 LGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 303 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 304 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 363 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV Sbjct 364 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 423 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA Sbjct 424 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 483 Query 481 VRAVIR 486 VRAVIR Sbjct 484 VRAVIR 489 >gi|308369635|ref|ZP_07666766.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis SUMu002] gi|308370926|ref|ZP_07667047.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis SUMu003] gi|308372152|ref|ZP_07427617.2| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis SUMu004] 11 more sequence titles Length=489 Score = 931 bits (2405), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/486 (99%), Positives = 484/486 (99%), Gaps = 0/486 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 4 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 63 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPG SPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 64 VQQITGYALVVASPGLSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 123 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 124 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 183 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 184 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 243 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 244 LGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 303 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 304 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 363 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV Sbjct 364 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 423 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA Sbjct 424 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 483 Query 481 VRAVIR 486 VRAVIR Sbjct 484 VRAVIR 489 >gi|15841647|ref|NP_336684.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium tuberculosis CDC1551] gi|254232314|ref|ZP_04925641.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase murD [Mycobacterium tuberculosis C] gi|254364959|ref|ZP_04981005.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase murD [Mycobacterium tuberculosis str. Haarlem] gi|13881899|gb|AAK46498.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium tuberculosis CDC1551] gi|124601373|gb|EAY60383.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase murD [Mycobacterium tuberculosis C] gi|134150473|gb|EBA42518.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase murD [Mycobacterium tuberculosis str. Haarlem] Length=496 Score = 930 bits (2404), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/486 (99%), Positives = 484/486 (99%), Gaps = 0/486 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 11 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 70 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPGFSPA PLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 71 VQQITGYALVVASPGFSPAIPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 130 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 131 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 190 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 191 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 250 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 251 LGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 310 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 311 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 370 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV Sbjct 371 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 430 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA Sbjct 431 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 490 Query 481 VRAVIR 486 VRAVIR Sbjct 491 VRAVIR 496 >gi|340627163|ref|YP_004745615.1| putative UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium canettii CIPT 140010059] gi|340005353|emb|CCC44511.1| putative UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium canettii CIPT 140010059] Length=486 Score = 930 bits (2403), Expect = 0.0, Method: Compositional matrix adjust. Identities = 483/486 (99%), Positives = 484/486 (99%), Gaps = 0/486 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 +LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 1 MLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPR WLVVTG Sbjct 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRRWLVVTG 120 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 241 LGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV Sbjct 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA Sbjct 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 Query 481 VRAVIR 486 VRAVIR Sbjct 481 VRAVIR 486 >gi|339632187|ref|YP_004723829.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase [Mycobacterium africanum GM041182] gi|339331543|emb|CCC27237.1| putative UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium africanum GM041182] Length=486 Score = 929 bits (2402), Expect = 0.0, Method: Compositional matrix adjust. Identities = 483/486 (99%), Positives = 484/486 (99%), Gaps = 0/486 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 +LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 1 MLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 241 LGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVA EDTGMPATVEVPVACV Sbjct 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVADEDTGMPATVEVPVACV 420 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA Sbjct 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 Query 481 VRAVIR 486 VRAVIR Sbjct 481 VRAVIR 486 >gi|339295071|gb|AEJ47182.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium tuberculosis CCDC5079] gi|339298693|gb|AEJ50803.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium tuberculosis CCDC5180] Length=469 Score = 902 bits (2331), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/469 (99%), Positives = 468/469 (99%), Gaps = 0/469 (0%) Query 18 VTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQQITGYALVVASPGFS 77 +TGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQQITGYALVVASPGFS Sbjct 1 MTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQQITGYALVVASPGFS 60 Query 78 PATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGKTTTTSMLHAMLIA 137 PATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGKTTTTSMLHAMLIA Sbjct 61 PATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGKTTTTSMLHAMLIA 120 Query 138 GGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPEAGAVLNIAEDHLDWHA 197 GGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPEAGAVLNIAEDHLDWHA Sbjct 121 GGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPEAGAVLNIAEDHLDWHA 180 Query 198 TMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLGEPAARELGVRDAHLV 257 TMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLGEPAA ELGVRDAHLV Sbjct 181 TMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLGEPAAGELGVRDAHLV 240 Query 258 DRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIADAVTSFRVGRHRAEV 317 DRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIADAVTSFRVGRHRAEV Sbjct 241 DRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIADAVTSFRVGRHRAEV 300 Query 318 VAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLHAEVAAMASRLVGAVL 377 VAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLHAEVAAMASRLVGAVL Sbjct 301 VAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLHAEVAAMASRLVGAVL 360 Query 378 IGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVLDVAKDDKAGETVGAAV 437 IGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVLDVAKDDKAGETVGAAV Sbjct 361 IGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVLDVAKDDKAGETVGAAV 420 Query 438 MTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAVRAVIR 486 MTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAVRAVIR Sbjct 421 MTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAVRAVIR 469 >gi|289447783|ref|ZP_06437527.1| UDP-N-acetylMuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis CPHL_A] gi|289420741|gb|EFD17942.1| UDP-N-acetylMuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis CPHL_A] Length=426 Score = 815 bits (2106), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/426 (99%), Positives = 424/426 (99%), Gaps = 0/426 (0%) Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 +QQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 1 MQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 60 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 61 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 120 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 121 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 180 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 181 LGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 240 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 241 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 300 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV Sbjct 301 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 360 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATA 480 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFT YADRGEAFATA Sbjct 361 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTAYADRGEAFATA 420 Query 481 VRAVIR 486 VRAVIR Sbjct 421 VRAVIR 426 >gi|289750752|ref|ZP_06510130.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis T92] gi|289691339|gb|EFD58768.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis T92] Length=411 Score = 778 bits (2009), Expect = 0.0, Method: Compositional matrix adjust. Identities = 405/411 (99%), Positives = 406/411 (99%), Gaps = 0/411 (0%) Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 +QQITGYAL PGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 1 MQQITGYALWSPVPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 60 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 61 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 120 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 121 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 180 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 181 LGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 240 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS Sbjct 241 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 300 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV Sbjct 301 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 360 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYA 471 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYA Sbjct 361 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYA 411 >gi|240168219|ref|ZP_04746878.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium kansasii ATCC 12478] Length=490 Score = 680 bits (1754), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/475 (82%), Positives = 416/475 (88%), Gaps = 6/475 (1%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 VLDPL PGAPVL+AGGRVTG+AV A LTRF ATPTVCDDDP ML+P+A+ G+ TV S A Sbjct 11 VLDPLVPGAPVLIAGGRVTGRAVLAALTRFRATPTVCDDDPAMLQPYADEGVATVEPSVA 70 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 V QI Y+LVV SPGF P TP+LAAAAAAGVPIWGDVELAWRLDAAG YGPPR WLVVTG Sbjct 71 VSQIAEYSLVVTSPGFQPTTPVLAAAAAAGVPIWGDVELAWRLDAAGRYGPPRRWLVVTG 130 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAML A GRR+VLCGNIGS VL+VLD+PA++LAVELSSFQL+WAPSLRP Sbjct 131 TNGKTTTTSMLHAMLTAAGRRSVLCGNIGSPVLEVLDQPADVLAVELSSFQLYWAPSLRP 190 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAG VLNIAEDHLDWH TMA YT AKARVLTG VAV GLDDSRAAALL+ +PAQVR GFR Sbjct 191 EAGVVLNIAEDHLDWHGTMAAYTEAKARVLTGRVAVVGLDDSRAAALLETAPAQVRAGFR 250 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRD HLVDRAF+ DL LLPVASIPVPGPVGVLDALAAAALARSVGV AGA Sbjct 251 LGEPAAGELGVRDGHLVDRAFAADLPLLPVASIPVPGPVGVLDALAAAALARSVGVSAGA 310 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IA+AV SF+VGRHR+EVVAV DG+TYVDDSKATNPHAA+ASVLAYPRVVW+AGGLLKGAS Sbjct 311 IAEAVASFQVGRHRSEVVAVVDGVTYVDDSKATNPHAAQASVLAYPRVVWLAGGLLKGAS 370 Query 361 LHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACV 420 + AEVA MA RLVGAVLIGRDRAAVAEALSRHAPDVPVVQVV GED GM VA Sbjct 371 VDAEVARMAPRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVTGEDAGM------AVASD 424 Query 421 LDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGE 475 DV K D + E +G VMTAAVAAA++MA+PGDTVLLAPAGASFDQF GYADRG+ Sbjct 425 TDVTKVDDSVEPLGTCVMTAAVAAAKQMAKPGDTVLLAPAGASFDQFNGYADRGD 479 >gi|15827432|ref|NP_301695.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium leprae TN] gi|221229909|ref|YP_002503325.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium leprae Br4923] gi|13431703|sp|P57995.1|MURD_MYCLE RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|259509790|sp|B8ZQP8.1|MURD_MYCLB RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|3080475|emb|CAA18670.1| udp-n-acetylmuramoylalanine-- d-glutamate ligase [Mycobacterium leprae] gi|13092982|emb|CAC31293.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase [Mycobacterium leprae] gi|219933016|emb|CAR71007.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase [Mycobacterium leprae Br4923] Length=490 Score = 645 bits (1665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/493 (76%), Positives = 406/493 (83%), Gaps = 10/493 (2%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 +LD L PGAPVLVAGG VTG+AV A LTRFG T+CDDDP L+ +A+ G+ TVS++ A Sbjct 1 MLDTLVPGAPVLVAGGGVTGRAVLAALTRFGMAATLCDDDPAALQQYADNGVATVSAATA 60 Query 61 VQQI----TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWL 116 QQ+ Y LVV SPGF+P TP+L AA+AA VPIWGDVELAWRLDAAG YGPPR WL Sbjct 61 TQQMFERGRKYVLVVTSPGFAPTTPVLVAASAARVPIWGDVELAWRLDAAGYYGPPRRWL 120 Query 117 VVTGTNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDE---PAELLAVELSSFQLH 173 VVTGTNGKTTTTSMLHAML A RR++LCGNIG VLDVL E P++ LAVELSSFQLH Sbjct 121 VVTGTNGKTTTTSMLHAMLAADNRRSLLCGNIGRPVLDVLTEFAEPSDFLAVELSSFQLH 180 Query 174 WAPSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPA 233 WAPSLRPEAG VLNIAEDHLDWH+TMA+YT AKARVLTG VAV GLDDSRAAALL + A Sbjct 181 WAPSLRPEAGVVLNIAEDHLDWHSTMADYTMAKARVLTGRVAVVGLDDSRAAALLSTTVA 240 Query 234 QVRVGFRLGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARS 293 VRVGFR GEPA ELGVRD +LVDRAF++DL L+PV SIPV GPVGVLDALAAAALARS Sbjct 241 PVRVGFRFGEPAVGELGVRDGYLVDRAFAEDLALMPVTSIPVSGPVGVLDALAAAALARS 300 Query 294 VGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAG 353 VGV A AIADAV FR+GRHRAEVVAVADGI YVDDSKATNPHAA SVLAYPRVVW+AG Sbjct 301 VGVGATAIADAVALFRLGRHRAEVVAVADGIRYVDDSKATNPHAALVSVLAYPRVVWVAG 360 Query 354 GLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATV 413 GLLKGAS+ AEVA MA +LVGAVLIGRDRA VAEALSRHAP+VPVVQVVAGED GM A Sbjct 361 GLLKGASVDAEVARMAPQLVGAVLIGRDRAMVAEALSRHAPNVPVVQVVAGEDAGMHA-- 418 Query 414 EVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADR 473 V V DV G T+G VM AAVAAAR +AQPGDTVLLAPAGASFDQF+GYADR Sbjct 419 -VAVVSGTDVISISDVGGTIGTRVMVAAVAAARDLAQPGDTVLLAPAGASFDQFSGYADR 477 Query 474 GEAFATAVRAVIR 486 G+ FATAVRA IR Sbjct 478 GDTFATAVRAAIR 490 >gi|183983185|ref|YP_001851476.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium marinum M] gi|183176511|gb|ACC41621.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium marinum M] Length=488 Score = 644 bits (1660), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/483 (79%), Positives = 405/483 (84%), Gaps = 14/483 (2%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 +LDPL PGAPVLVAG RVTG+AV A LTRFGA PT+CDDDP MLRP AE G+ TV S A Sbjct 1 MLDPLVPGAPVLVAGARVTGRAVLAALTRFGAIPTMCDDDPAMLRPFAESGVATVDPSVA 60 Query 61 VQQI--------TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPP 112 VQQ+ + YALVV SPGF P+TP+LAAAAAAGVPIWGDVELAWRLDAAGCYGPP Sbjct 61 VQQLAQPEASPESRYALVVTSPGFQPSTPVLAAAAAAGVPIWGDVELAWRLDAAGCYGPP 120 Query 113 RSWLVVTGTNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQL 172 R WLVVTGTNGKTTTTSMLHAML+AG R+VLCGNIGS VLDVL+EPA+LLAVELSSFQL Sbjct 121 RRWLVVTGTNGKTTTTSMLHAMLVAGQHRSVLCGNIGSPVLDVLEEPADLLAVELSSFQL 180 Query 173 HWAPSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSP 232 HWAPSLRPEAG VLNIAEDHLDWH TMA YT AKARVLTG VAV GLDDSRAAAL D +P Sbjct 181 HWAPSLRPEAGVVLNIAEDHLDWHGTMAAYTEAKARVLTGRVAVVGLDDSRAAALRDTAP 240 Query 233 AQVRVGFRLGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALAR 292 A VRVGFR+G PA ELG+RD HLVDRAFSDDL LLP +SIPVPGPVGVLD LAAAALAR Sbjct 241 APVRVGFRIGAPAVGELGLRDGHLVDRAFSDDLVLLPASSIPVPGPVGVLDTLAAAALAR 300 Query 293 SVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIA 352 +VGV A AIADAV SF+VGRHR+EVV V DGITYVDDSKATNPHAA ASVLAYPRVVW+A Sbjct 301 AVGVSADAIADAVASFQVGRHRSEVVEVVDGITYVDDSKATNPHAAEASVLAYPRVVWVA 360 Query 353 GGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPAT 412 GGLLKGAS+ AEVA MASRLVGAVLIG+DRA VAEALSRHAPDVPVVQVV ED M Sbjct 361 GGLLKGASVDAEVARMASRLVGAVLIGQDRAEVAEALSRHAPDVPVVQVVTSEDADMGE- 419 Query 413 VEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYAD 472 AC V K D G ++GA VM AAVAAAR MA+ GDTVLLAPAGASFDQFT Y D Sbjct 420 -----ACGASVTKVDDVGGSLGARVMRAAVAAARNMARSGDTVLLAPAGASFDQFTSYGD 474 Query 473 RGE 475 RG+ Sbjct 475 RGD 477 >gi|118618797|ref|YP_907129.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium ulcerans Agy99] gi|118570907|gb|ABL05658.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium ulcerans Agy99] Length=488 Score = 635 bits (1638), Expect = 5e-180, Method: Compositional matrix adjust. Identities = 376/483 (78%), Positives = 403/483 (84%), Gaps = 14/483 (2%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 +LDPL PGAPVLVAG RVTG+AV A LTRFGA PT+CDDDP MLRP AE G+ TV S A Sbjct 1 MLDPLVPGAPVLVAGARVTGRAVLAALTRFGAIPTMCDDDPAMLRPFAESGVATVDPSVA 60 Query 61 VQQI--------TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPP 112 VQQ+ + YALVV SPGF P+TP+LAAAAAAGVPIWGDVELAWRLDAAGCYGPP Sbjct 61 VQQLAQPEPSSESRYALVVTSPGFQPSTPVLAAAAAAGVPIWGDVELAWRLDAAGCYGPP 120 Query 113 RSWLVVTGTNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQL 172 R WLVVTGTNGKTTTTSMLHAML+AG R+VLCGNIGS VLDVL+EPA+LLAVELSSFQL Sbjct 121 RRWLVVTGTNGKTTTTSMLHAMLVAGQHRSVLCGNIGSPVLDVLEEPADLLAVELSSFQL 180 Query 173 HWAPSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSP 232 WAPSLRPEAG VLNIAEDHLDWH TMA YT AKARVLTG VAV GLDDSRAAAL D +P Sbjct 181 RWAPSLRPEAGVVLNIAEDHLDWHGTMAAYTEAKARVLTGRVAVVGLDDSRAAALRDTAP 240 Query 233 AQVRVGFRLGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALAR 292 A VRVGFR+G PA ELG+RD HLVDRAFSDDL LLP +SIPVPGPVGVLD LAAAALAR Sbjct 241 APVRVGFRIGTPAVGELGLRDGHLVDRAFSDDLVLLPASSIPVPGPVGVLDTLAAAALAR 300 Query 293 SVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIA 352 +VGV A AIADAV SF+VGRHR+EVV V DGITYVDDSKATNPHAA ASVLAYPRVVW+A Sbjct 301 AVGVSADAIADAVASFQVGRHRSEVVEVVDGITYVDDSKATNPHAAEASVLAYPRVVWVA 360 Query 353 GGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPAT 412 GGLLKGAS+ AEVA MA+RLVGAVLIG+DRA VAEALSRHAPDVPVVQVV ED M Sbjct 361 GGLLKGASVDAEVARMAARLVGAVLIGQDRAEVAEALSRHAPDVPVVQVVTSEDADMGE- 419 Query 413 VEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYAD 472 A V K D G ++GA VM AAVAAAR MA+ GDTVLLAPAGASFDQFT Y D Sbjct 420 -----AYGASVTKVDDVGGSLGARVMRAAVAAARNMARSGDTVLLAPAGASFDQFTSYGD 474 Query 473 RGE 475 RG+ Sbjct 475 RGD 477 >gi|336461945|gb|EGO40797.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium avium subsp. paratuberculosis S397] Length=489 Score = 632 bits (1631), Expect = 3e-179, Method: Compositional matrix adjust. Identities = 383/485 (79%), Positives = 411/485 (85%), Gaps = 3/485 (0%) Query 2 LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV 61 L PL PGAPVLVAGG +TG+AV A L RFGA PT+CDDDP LR + + G+ TVS+S A Sbjct 8 LAPLSPGAPVLVAGGGITGRAVLAALRRFGAAPTLCDDDPATLRGYVDSGVDTVSTSAAA 67 Query 62 QQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGT 121 ++I+ YALVV SPGF+P PL AAAAAGVP+WGDVELAWRLD AG YGPPR WLVVTGT Sbjct 68 ERISRYALVVTSPGFAPTAPLPLAAAAAGVPVWGDVELAWRLDVAGHYGPPRRWLVVTGT 127 Query 122 NGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPE 181 NGKTTTTSMLHAML A GRR++LCGNIGS VLDVLD+PAELLAVELSSFQLHWAPSLRPE Sbjct 128 NGKTTTTSMLHAMLTAAGRRSLLCGNIGSPVLDVLDQPAELLAVELSSFQLHWAPSLRPE 187 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 GAVLNIAEDHLDWH T+A+Y AAKARVL G VAV GLDDSRAAALL + A VRVGFRL Sbjct 188 GGAVLNIAEDHLDWHGTLADYAAAKARVLDGRVAVVGLDDSRAAALLSTARAPVRVGFRL 247 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 GEPAA ELGVR LVDRAF+DDLTLLPV SIPVPGPVGVLDALAAAALAR V VPA I Sbjct 248 GEPAAGELGVRGGQLVDRAFADDLTLLPVDSIPVPGPVGVLDALAAAALARCVDVPASPI 307 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 A+A+ SFRVGRHRAEVVAVADGITYVDDSKATNPHAA ASVLAYPRVVWIAGGLLKGAS+ Sbjct 308 AEAIVSFRVGRHRAEVVAVADGITYVDDSKATNPHAAEASVLAYPRVVWIAGGLLKGASV 367 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 AEVA MASRLVGAVLIGRDR VAEALSRHAPDVPVV VV GED GM AT PV Sbjct 368 DAEVARMASRLVGAVLIGRDRREVAEALSRHAPDVPVVHVVTGEDAGMDAT---PVVFGA 424 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAV 481 +V K G +GAAVM+AAVAAAR +A+PGDTVLLAPAGASFDQF GYADRG+AFA AV Sbjct 425 NVTKVKHLGGDLGAAVMSAAVAAARDLAKPGDTVLLAPAGASFDQFAGYADRGDAFAAAV 484 Query 482 RAVIR 486 RA IR Sbjct 485 RAAIR 489 >gi|289570272|ref|ZP_06450499.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis T17] gi|289544026|gb|EFD47674.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis T17] Length=395 Score = 631 bits (1628), Expect = 7e-179, Method: Compositional matrix adjust. Identities = 351/375 (94%), Positives = 356/375 (95%), Gaps = 0/375 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 11 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 70 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 71 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 130 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 131 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 190 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 191 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 250 Query 241 LGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 300 LGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA Sbjct 251 LGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGA 310 Query 301 IADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGAS 360 IADAVTSFRVGRHRA+ VAVADGITY +DSKATNPHAA+ SVL YPRV WI GGL KGAS Sbjct 311 IADAVTSFRVGRHRAKAVAVADGITYREDSKATNPHAAQPSVLDYPRVEWIEGGLHKGAS 370 Query 361 LHAEVAAMASRLVGA 375 + S G+ Sbjct 371 FTPSLEQWVSFWSGS 385 >gi|41407997|ref|NP_960833.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium avium subsp. paratuberculosis K-10] gi|60390511|sp|Q73YQ6.1|MURD_MYCPA RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|41396351|gb|AAS04216.1| MurD [Mycobacterium avium subsp. paratuberculosis K-10] Length=489 Score = 631 bits (1627), Expect = 9e-179, Method: Compositional matrix adjust. Identities = 383/485 (79%), Positives = 410/485 (85%), Gaps = 3/485 (0%) Query 2 LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV 61 L PL PGAPVLVAGG +TG+AV A L RFGA PT+CDDDP LR + + G+ TVS+S A Sbjct 8 LAPLSPGAPVLVAGGGITGRAVLAALRRFGAAPTLCDDDPATLRGYVDSGVDTVSTSAAA 67 Query 62 QQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGT 121 ++I+ YALVV SPGF+P PL AAAAAGVP+WGDVELAWRLD AG YGPPR WLVVTGT Sbjct 68 ERISRYALVVTSPGFAPTAPLPLAAAAAGVPVWGDVELAWRLDVAGHYGPPRRWLVVTGT 127 Query 122 NGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPE 181 NGKTTTTSMLHAML A GRR++LCGNIGS VLDVLD+PAELLAVELSSFQLHWAPSLRPE Sbjct 128 NGKTTTTSMLHAMLTAAGRRSLLCGNIGSPVLDVLDQPAELLAVELSSFQLHWAPSLRPE 187 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 GAVLNIAEDHLDWH T+A+Y AAKARVL G VAV GLDDSRAAALL + A VRVGFRL Sbjct 188 GGAVLNIAEDHLDWHGTLADYAAAKARVLDGRVAVVGLDDSRAAALLSTARAPVRVGFRL 247 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 GEPAA ELGVR LVDRAF+DDLTLLPV SIPVPGPVGVLDALAAAALAR V VPA I Sbjct 248 GEPAAGELGVRGGQLVDRAFADDLTLLPVDSIPVPGPVGVLDALAAAALARCVDVPASPI 307 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 A+A+ SFRVGRHRAEVVAVADGITYVDDSKATNPHAA ASVLAYPRVVWIAGGLLKGAS+ Sbjct 308 AEAIVSFRVGRHRAEVVAVADGITYVDDSKATNPHAAEASVLAYPRVVWIAGGLLKGASV 367 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 AEVA MAS LVGAVLIGRDR VAEALSRHAPDVPVV VV GED GM AT PV Sbjct 368 DAEVARMASWLVGAVLIGRDRREVAEALSRHAPDVPVVHVVTGEDAGMDAT---PVVFGA 424 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAV 481 +V K G +GAAVM+AAVAAAR +A+PGDTVLLAPAGASFDQF GYADRGEAFA AV Sbjct 425 NVTKVKHLGGDLGAAVMSAAVAAARDLAKPGDTVLLAPAGASFDQFAGYADRGEAFAAAV 484 Query 482 RAVIR 486 RA IR Sbjct 485 RAAIR 489 >gi|118463229|ref|YP_881538.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium avium 104] gi|158512437|sp|A0QF50.1|MURD_MYCA1 RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|118164516|gb|ABK65413.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium avium 104] Length=489 Score = 630 bits (1624), Expect = 2e-178, Method: Compositional matrix adjust. Identities = 382/485 (79%), Positives = 410/485 (85%), Gaps = 3/485 (0%) Query 2 LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV 61 L PL PGAPVLVAGG +TG+AV A L RFGA PT+CDDDP LR + + G+ TVS+S A Sbjct 8 LAPLSPGAPVLVAGGGITGRAVLAALRRFGAAPTLCDDDPATLRGYVDSGVDTVSTSAAA 67 Query 62 QQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGT 121 ++I+ YALVV SPGF+P PL AAAAAGVP+WGDVELAWRLDAAG YGPPR WLVVTGT Sbjct 68 ERISRYALVVTSPGFAPTAPLPLAAAAAGVPVWGDVELAWRLDAAGHYGPPRRWLVVTGT 127 Query 122 NGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPE 181 NGKTTTTSMLHAML A GRR++LCGNIGS VLDVLD+PAELLAVELSSFQLHWAPSLRPE Sbjct 128 NGKTTTTSMLHAMLTAAGRRSLLCGNIGSPVLDVLDQPAELLAVELSSFQLHWAPSLRPE 187 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 GAVLNIAEDHLDWH T+A+Y AAKARVL G VAV GLDDSRAAALL + A VRVGFRL Sbjct 188 GGAVLNIAEDHLDWHGTLADYAAAKARVLDGRVAVVGLDDSRAAALLSTARAPVRVGFRL 247 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 GEPAA ELGVR LVDRAF+DDLTLLPV SIPVPGPVGVLDALAAAALAR V VPA I Sbjct 248 GEPAAGELGVRGGQLVDRAFADDLTLLPVDSIPVPGPVGVLDALAAAALARCVDVPASPI 307 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 A+A+ SFRVGRHRAEVVAVADGITYVDDSKATNPHAA ASVLAYPRVVWIAGGLLKGAS+ Sbjct 308 AEAIVSFRVGRHRAEVVAVADGITYVDDSKATNPHAAEASVLAYPRVVWIAGGLLKGASV 367 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 A VA MASRLVGAVLIGRDR VAEALSRHAPDVPVV VV GED GM AT PV Sbjct 368 DAVVARMASRLVGAVLIGRDRREVAEALSRHAPDVPVVHVVTGEDAGMDAT---PVVFGA 424 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAV 481 +V K G +GAAVM+AAVAAAR +A+PGDTVLLAPA ASFDQF GYADRG+AFA AV Sbjct 425 NVTKVKHLGGDLGAAVMSAAVAAARDLAKPGDTVLLAPAAASFDQFAGYADRGDAFAAAV 484 Query 482 RAVIR 486 RA IR Sbjct 485 RAAIR 489 >gi|254775006|ref|ZP_05216522.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium avium subsp. avium ATCC 25291] Length=489 Score = 627 bits (1616), Expect = 2e-177, Method: Compositional matrix adjust. Identities = 381/485 (79%), Positives = 409/485 (85%), Gaps = 3/485 (0%) Query 2 LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV 61 L PL PGAPVLVAGG +TG+AV A L RFGA PT+CDDDP LR + + G+ TVS+S A Sbjct 8 LAPLSPGAPVLVAGGGITGRAVLAALRRFGAAPTLCDDDPATLRGYVDSGVDTVSTSAAA 67 Query 62 QQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGT 121 ++I+ YALVV SPG +P PL AAAAAGVP+WGDVELAWRLDAAG YGPPR WLVVTGT Sbjct 68 ERISRYALVVTSPGLAPTAPLPLAAAAAGVPVWGDVELAWRLDAAGHYGPPRRWLVVTGT 127 Query 122 NGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPE 181 NGKTTTTSMLHAML A GRR++LCGNIGS VLDVLD+PAELLAVELSSFQLHWAPSLRPE Sbjct 128 NGKTTTTSMLHAMLTAAGRRSLLCGNIGSPVLDVLDQPAELLAVELSSFQLHWAPSLRPE 187 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 GAVLNIAEDHLDWH T+A+Y AAKARVL G VAV GLDDSRAAALL + A VRVGFRL Sbjct 188 GGAVLNIAEDHLDWHGTLADYAAAKARVLDGRVAVVGLDDSRAAALLSTARAPVRVGFRL 247 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 GEPAA ELGVR LVDRAF+DDLTLLPV SIPVPGPVGVLDALAAAALAR V VPA I Sbjct 248 GEPAAGELGVRGGQLVDRAFADDLTLLPVDSIPVPGPVGVLDALAAAALARCVDVPASPI 307 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 A+A+ SFRVGRHRAEVVAVADGITYVDDSKATNPHAA ASVLAYPRVVWIAGGLLKGAS+ Sbjct 308 AEAIVSFRVGRHRAEVVAVADGITYVDDSKATNPHAAEASVLAYPRVVWIAGGLLKGASV 367 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 A VA MASRLVGAVLIGRDR VAEALSRHAPDVPVV VV GED GM AT PV Sbjct 368 DAVVARMASRLVGAVLIGRDRREVAEALSRHAPDVPVVHVVTGEDAGMDAT---PVVFGA 424 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAV 481 +V K G +GAAVM+AAVAAAR +A+PGDTVLLAPA ASFDQF GYADRG+AFA AV Sbjct 425 NVTKVKHLGGDLGAAVMSAAVAAARDLAKPGDTVLLAPAAASFDQFAGYADRGDAFAAAV 484 Query 482 RAVIR 486 RA IR Sbjct 485 RAAIR 489 >gi|296166023|ref|ZP_06848474.1| UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898622|gb|EFG78177.1| UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=488 Score = 620 bits (1598), Expect = 2e-175, Method: Compositional matrix adjust. Identities = 373/474 (79%), Positives = 407/474 (86%), Gaps = 3/474 (0%) Query 2 LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV 61 L PL PGAPVLVAGG VTG+AV A L+RFGA PT+CDDDP LR +A+ G T + S A Sbjct 7 LGPLAPGAPVLVAGGGVTGKAVLAALSRFGAAPTLCDDDPATLRRYADTGAATATMSSAT 66 Query 62 QQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGT 121 Q++ YALVV SPGFSP TPLL AAAAAGVP+WGDVELAWRLDAAG YGPPR WLVVTGT Sbjct 67 QRVAEYALVVTSPGFSPDTPLLVAAAAAGVPVWGDVELAWRLDAAGRYGPPRRWLVVTGT 126 Query 122 NGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPE 181 NGKTTTTSMLHAML A GRR+VLCGNIG VLDVLD PA+LLAVELSSFQLHWAPS+RPE Sbjct 127 NGKTTTTSMLHAMLTAAGRRSVLCGNIGDPVLDVLDRPADLLAVELSSFQLHWAPSVRPE 186 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 AG VLNIAEDHLDWHATMAEYTAAKARVL G VAV GLDD+RAAALLD + A VRVGFRL Sbjct 187 AGVVLNIAEDHLDWHATMAEYTAAKARVLDGRVAVVGLDDARAAALLDTAAAPVRVGFRL 246 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 GEPAA ELGVRD L+DRAF+DDL LLPV SIPVPGPVG+LDALAAAALARSV VPA AI Sbjct 247 GEPAAGELGVRDGRLIDRAFADDLALLPVDSIPVPGPVGILDALAAAALARSVDVPAEAI 306 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 ADA+ +FRVGRHRAEV+AVADG+TYVDDSKATNPHAA ASVLAYPRV+W+AGGLLKGAS+ Sbjct 307 ADAIAAFRVGRHRAEVIAVADGVTYVDDSKATNPHAAEASVLAYPRVIWVAGGLLKGASV 366 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 AEVA MA RLVGAVLIGRDR VAEALSRHAPDVPVVQVV GED M AT V + Sbjct 367 DAEVARMAPRLVGAVLIGRDRQEVAEALSRHAPDVPVVQVVTGEDADMNATA---VVIDV 423 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGE 475 DV + +G +GA+VM+AAVAAAR +A+PGDTVLLAPAGASFDQF+GYADRG+ Sbjct 424 DVTEVKPSGGDLGASVMSAAVAAARNLARPGDTVLLAPAGASFDQFSGYADRGD 477 >gi|342859871|ref|ZP_08716524.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium colombiense CECT 3035] gi|342133003|gb|EGT86223.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium colombiense CECT 3035] Length=489 Score = 611 bits (1576), Expect = 7e-173, Method: Compositional matrix adjust. Identities = 382/489 (79%), Positives = 413/489 (85%), Gaps = 7/489 (1%) Query 2 LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV 61 L+PL PGAPVLVAGG VTG+AV A L RFGA PT+CDDDP LR +A G+ T ++ A+ Sbjct 4 LEPLAPGAPVLVAGGGVTGKAVLAALRRFGAAPTLCDDDPARLRGYAGAGVATAPTATAI 63 Query 62 QQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGT 121 +I+ YALVV SPGF+P TPLL AA AAGVPIWGDVELAWRLDAAG YGPPR WLVVTGT Sbjct 64 DEISRYALVVTSPGFAPTTPLLVAAQAAGVPIWGDVELAWRLDAAGHYGPPRRWLVVTGT 123 Query 122 NGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVL----DEPAELLAVELSSFQLHWAPS 177 NGKTTTTSMLHAML AGGRR++LCGNIG VLDVL DEPAELLAVELSSFQLHWAPS Sbjct 124 NGKTTTTSMLHAMLTAGGRRSLLCGNIGDPVLDVLGDDTDEPAELLAVELSSFQLHWAPS 183 Query 178 LRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRV 237 L+PEAGAVLNIAEDHLDWH ++A Y AAKARVL G VAV GLDD+RAAALLD + A VRV Sbjct 184 LQPEAGAVLNIAEDHLDWHGSLAAYAAAKARVLDGRVAVVGLDDARAAALLDTARAPVRV 243 Query 238 GFRLGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVP 297 GFRLGEPAA ELGVRD HLVDRAF+DDL LL SIPVPGPVGVLDALAAAALAR V VP Sbjct 244 GFRLGEPAAGELGVRDGHLVDRAFADDLALLRADSIPVPGPVGVLDALAAAALARCVDVP 303 Query 298 AGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLK 357 A AIA A+ +FRVGRHRAEVVAVADGITYVDDSKATNPHAA ASVLAYPRVVWIAGGLLK Sbjct 304 AEAIAAAIAAFRVGRHRAEVVAVADGITYVDDSKATNPHAAEASVLAYPRVVWIAGGLLK 363 Query 358 GASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPV 417 GAS+ AEVA MASRLVGAVLIGRDR VAEALSRHAPDVPV+ VV GED GM AT V Sbjct 364 GASVDAEVARMASRLVGAVLIGRDRQEVAEALSRHAPDVPVLHVVTGEDAGMDATAVVSG 423 Query 418 ACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAF 477 A DV + + G+++GAAVM AAVAAAR +AQ GDTVLLAPAGASFDQF GYADRG+AF Sbjct 424 A---DVTEVKQTGDSLGAAVMNAAVAAARIVAQAGDTVLLAPAGASFDQFAGYADRGDAF 480 Query 478 ATAVRAVIR 486 A AVRA +R Sbjct 481 AAAVRAALR 489 >gi|333990381|ref|YP_004522995.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium sp. JDM601] gi|333486349|gb|AEF35741.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium sp. JDM601] Length=508 Score = 554 bits (1428), Expect = 1e-155, Method: Compositional matrix adjust. Identities = 341/488 (70%), Positives = 372/488 (77%), Gaps = 24/488 (4%) Query 5 LGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQQI 64 L GA VLVAG VTG+AV L G T+CDDDP LR H G+ T S + A QI Sbjct 5 LSSGARVLVAGAGVTGRAVLNALAPLGLDLTLCDDDPAALRAHT--GVTTCSPAQAGSQI 62 Query 65 TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGK 124 Y LVV SPGF+P TP+LAAAA AGVPIWGDVELAW+LDAAG YGPPR WLVVTGTNGK Sbjct 63 ADYTLVVTSPGFAPTTPVLAAAAEAGVPIWGDVELAWQLDAAGRYGPPRRWLVVTGTNGK 122 Query 125 TTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPA-------------------ELLAV 165 TTTTSMLHAML A GRRA LCGNIGS VLDVL EPA ELLAV Sbjct 123 TTTTSMLHAMLTAAGRRAALCGNIGSPVLDVLGEPAGGSARLDGGERKLGPPHESELLAV 182 Query 166 ELSSFQLHWAPSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAA 225 ELSSFQLHWAPSLRPEAGAVLNIAEDHLDWH +MA YTA KAR L G VAV GLDD+RAA Sbjct 183 ELSSFQLHWAPSLRPEAGAVLNIAEDHLDWHGSMAAYTADKARALAGRVAVVGLDDARAA 242 Query 226 ALLDGSPAQVRVGFRLGEPAARELGVRDAHLVDRAFS--DDLTLLPVASIPVPGPVGVLD 283 ALL GSPA V+ GFRLGEPAA ELGV D LVDRAF+ + + L PVASI VPGPVGVLD Sbjct 243 ALLGGSPAAVKAGFRLGEPAAGELGVIDGMLVDRAFAGAEAVALAPVASISVPGPVGVLD 302 Query 284 ALAAAALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVL 343 ALAAAALARSV VP AIA A+ SF+VGRHRAE+V VADGI+YVDDSKATNPHAA ASVL Sbjct 303 ALAAAALARSVAVPPEAIAAALASFQVGRHRAELVVVADGISYVDDSKATNPHAAEASVL 362 Query 344 AYPRVVWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVA 403 AYPRVVW+AGGLLKGAS+ A VA +A L GAVLIGRDR VA+ALSRHAPDVP+V V Sbjct 363 AYPRVVWVAGGLLKGASVEATVARIADHLAGAVLIGRDRGEVAKALSRHAPDVPLVFVET 422 Query 404 GEDTGMPATVEVPVACVLDVAK-DDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGA 462 G+D M E V+ V V + D + E++G+ VMTA VAAAR +A+PGDTVLLAPAGA Sbjct 423 GQDADMQVMGETAVSPVTRVTRVADGSDESLGSRVMTAVVAAARDLARPGDTVLLAPAGA 482 Query 463 SFDQFTGY 470 SFDQF GY Sbjct 483 SFDQFAGY 490 >gi|289745329|ref|ZP_06504707.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis 02_1987] gi|289685857|gb|EFD53345.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis 02_1987] Length=344 Score = 533 bits (1374), Expect = 2e-149, Method: Compositional matrix adjust. Identities = 308/322 (96%), Positives = 309/322 (96%), Gaps = 1/322 (0%) Query 166 ELSSFQLHW-APSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRA 224 SSFQLHW A + P NIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRA Sbjct 23 SCSSFQLHWGAVAAGPRPARCSNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRA 82 Query 225 AALLDGSPAQVRVGFRLGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDA 284 AALLDGSPAQVRVGFRLGEPAA ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDA Sbjct 83 AALLDGSPAQVRVGFRLGEPAAGELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDA 142 Query 285 LAAAALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLA 344 LAAAALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLA Sbjct 143 LAAAALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLA 202 Query 345 YPRVVWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAG 404 YPRVVWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAG Sbjct 203 YPRVVWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAG 262 Query 405 EDTGMPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASF 464 EDTGMPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASF Sbjct 263 EDTGMPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASF 322 Query 465 DQFTGYADRGEAFATAVRAVIR 486 DQFTGYADRGEAFATAVRAVIR Sbjct 323 DQFTGYADRGEAFATAVRAVIR 344 >gi|145223573|ref|YP_001134251.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium gilvum PYR-GCK] gi|315443920|ref|YP_004076799.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium sp. Spyr1] gi|145216059|gb|ABP45463.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium gilvum PYR-GCK] gi|315262223|gb|ADT98964.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium sp. Spyr1] Length=487 Score = 524 bits (1349), Expect = 2e-146, Method: Compositional matrix adjust. Identities = 325/479 (68%), Positives = 370/479 (78%), Gaps = 2/479 (0%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQQITGY 67 G VLV G RVTGQA+ A LT GA T+ DD P L A++G+ + + AV++I + Sbjct 11 GLSVLVTGARVTGQAILAALTPLGARATLTDDSPTALTAFAQQGVEVLDPAAAVERIAAF 70 Query 68 ALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGKTTT 127 LVV SPGF P P+LAAAA AGVPIWGDVELAWRLD +G +GPPR WLVVTGTNGKTTT Sbjct 71 DLVVTSPGFPPTAPVLAAAADAGVPIWGDVELAWRLDRSGRFGPPRQWLVVTGTNGKTTT 130 Query 128 TSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPEAGAVLN 187 TSMLHAML + GRRAVLCGNIG VL +L++PA++ AVELSSFQLHWAPSLRPEAGAVLN Sbjct 131 TSMLHAMLESAGRRAVLCGNIGDPVLTLLEQPADVFAVELSSFQLHWAPSLRPEAGAVLN 190 Query 188 IAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLGEPAAR 247 +AEDHLDWH +MA Y A KAR LTG VAV GLDD AA LL +PA V+VGFRLG P Sbjct 191 VAEDHLDWHGSMAAYAADKARALTGRVAVGGLDDEIAAGLLGSAPAAVKVGFRLGAPGPG 250 Query 248 ELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIADAVTS 307 E GVRD L+D AF+D L L V SIPV GPVGVL+ALAAAALAR+V VPA AIA A+ Sbjct 251 EFGVRDGALIDNAFADGLELAAVDSIPVAGPVGVLNALAAAALARAVDVPAEAIATALAG 310 Query 308 FRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLHAEVAA 367 F+VGRHRAEVVAVADGITYVDDSKATNPHAARAS+ AYPRVVWIAGG+LKGAS+ V+ Sbjct 311 FQVGRHRAEVVAVADGITYVDDSKATNPHAARASIDAYPRVVWIAGGMLKGASVEDLVSD 370 Query 368 MASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVLDVAKDD 427 A LVGAVLIGRDRA VAEAL+RHAPDVPVV++V GED+G+ E V V V + D Sbjct 371 SADHLVGAVLIGRDRAVVAEALARHAPDVPVVELVTGEDSGVLEKDESGVTRVTRVVQAD 430 Query 428 KAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAVRAVIR 486 E++ AVM AAV AAR +A PGD +LLAPAGASFDQFT Y RG+ FA AVRA +R Sbjct 431 S--ESLSDAVMAAAVRAARGLAAPGDAILLAPAGASFDQFTSYGHRGDTFAAAVRAALR 487 >gi|289762316|ref|ZP_06521694.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis GM 1503] gi|289709822|gb|EFD73838.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase MurD [Mycobacterium tuberculosis GM 1503] Length=282 Score = 514 bits (1324), Expect = 1e-143, Method: Compositional matrix adjust. Identities = 261/265 (99%), Positives = 262/265 (99%), Gaps = 0/265 (0%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 +LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA Sbjct 1 MLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDA 60 Query 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG Sbjct 61 VQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTG 120 Query 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP Sbjct 121 TNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRP 180 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR Sbjct 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFR 240 Query 241 LGEPAARELGVRDAHLVDRAFSDDL 265 LGEPAA ELGVRDAHLVDRAFS L Sbjct 241 LGEPAAGELGVRDAHLVDRAFSRRL 265 >gi|118470144|ref|YP_888506.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium smegmatis str. MC2 155] gi|158512472|sp|A0R018.1|MURD_MYCS2 RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|118171431|gb|ABK72327.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium smegmatis str. MC2 155] Length=493 Score = 514 bits (1323), Expect = 1e-143, Method: Compositional matrix adjust. Identities = 317/475 (67%), Positives = 364/475 (77%), Gaps = 1/475 (0%) Query 2 LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV 61 L PL PGA VLV G +TG+AV L T+CDD+ L A +G+ ++ DA+ Sbjct 8 LAPLTPGARVLVTGAGITGRAVLGALAPLEVAATLCDDNADALAALAAKGVAVIAPGDAI 67 Query 62 QQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGT 121 I YALVV SPGF+P+ P+LAAAAAAGVPIWGDVELAWRLDAAG YGPPR WLVVTGT Sbjct 68 ASIGDYALVVTSPGFAPSAPVLAAAAAAGVPIWGDVELAWRLDAAGRYGPPRRWLVVTGT 127 Query 122 NGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPE 181 NGKTTTTSMLH ML+AGGRR+VLCGNIG VL VLD+PAELLAVELSSFQLHWAPSLRPE Sbjct 128 NGKTTTTSMLHDMLVAGGRRSVLCGNIGDPVLAVLDQPAELLAVELSSFQLHWAPSLRPE 187 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 AG VLN+AEDHLDWH +MA Y KARVL G VAV GLDD AA LL + A VRVGFRL Sbjct 188 AGVVLNVAEDHLDWHGSMAAYARDKARVLDGRVAVVGLDDPVAAGLLPTAAATVRVGFRL 247 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 G+PAA ELGVRD L+DRAF D + L A I V GP+GVLDAL AAALAR+VGV GAI Sbjct 248 GDPAAGELGVRDGKLIDRAFDDGVELADCADIGVAGPIGVLDALGAAALARAVGVAPGAI 307 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 A+ SF+VGRHRAEVV DG+ ++DDSKATNPHAA+AS+ AY RVVW+AGGLLKGAS+ Sbjct 308 GAALASFQVGRHRAEVVGTVDGVVFIDDSKATNPHAAQASITAYDRVVWVAGGLLKGASV 367 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 V +A+RL GAVLIGRDR VA+ALSRHAPDVPVV++VAGED+G+ T E + Sbjct 368 DELVRQVANRLAGAVLIGRDRQMVADALSRHAPDVPVVELVAGEDSGVLGTNESIESVGD 427 Query 422 DVAK-DDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGE 475 V + + G V AVM+A V+AAR +A PGDTVLLAPAGASFDQF+GY RG+ Sbjct 428 HVTRVIEVGGRPVSDAVMSAVVSAARDLASPGDTVLLAPAGASFDQFSGYGQRGD 482 >gi|126435847|ref|YP_001071538.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium sp. JLS] gi|126235647|gb|ABN99047.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium sp. JLS] Length=495 Score = 506 bits (1302), Expect = 5e-141, Method: Compositional matrix adjust. Identities = 327/495 (67%), Positives = 371/495 (75%), Gaps = 19/495 (3%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLR----PHAERGLPTVS 56 V++PL PGA VL+ G +TG++V+AVL G T+CDDDP+ L+ P A V+ Sbjct 5 VVEPLTPGARVLITGAGLTGRSVSAVLEPTGVRLTICDDDPLALQRLITPAA-----VVT 59 Query 57 SSDAVQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWL 116 + +AV I YALVV SPGF P P+L+AAAAAGVPIWGDVELAWRLD AG +GPPR WL Sbjct 60 TGEAVAGIADYALVVTSPGFPPTAPVLSAAAAAGVPIWGDVELAWRLDRAGWFGPPRRWL 119 Query 117 VVTGTNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVL--------DEPAELLAVELS 168 VVTGTNGKTTTTSML+A+L A RR +LCGNIG+ VLDVL DE ELLAVELS Sbjct 120 VVTGTNGKTTTTSMLYAILRAADRRVMLCGNIGNPVLDVLGESPRTRGDEEPELLAVELS 179 Query 169 SFQLHWAPSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALL 228 SFQLHWAPSLRP+AG VLN+AEDHLDWH +M Y KAR L G VAVAGLDD AA LL Sbjct 180 SFQLHWAPSLRPDAGVVLNVAEDHLDWHGSMTAYARDKARALDGRVAVAGLDDPVAAELL 239 Query 229 DGSPAQVRVGFRLGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAA 288 + A VRVGFRLG P A ELGV D LVD AF+D L L I V GPVGVL+ALAAA Sbjct 240 TTAAAPVRVGFRLGPPGAGELGVHDGWLVDNAFADGLRLARADDIRVAGPVGVLNALAAA 299 Query 289 ALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRV 348 ALAR+V VPA A+A A+ SF VGRHRAEVVAV+ G+T+VDDSKATNPHAARAS+ AYPRV Sbjct 300 ALARAVDVPAEAVAAALASFEVGRHRAEVVAVSGGVTWVDDSKATNPHAARASIAAYPRV 359 Query 349 VWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTG 408 VWIAGGLLKG S+ A VA +A RL G VLIGRDRA VAEALSRHAPDVPVV++V GED+G Sbjct 360 VWIAGGLLKGVSVDALVAEVADRLTGVVLIGRDRAVVAEALSRHAPDVPVVELVTGEDSG 419 Query 409 MPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFT 468 + T E V V V D G + AVM AAV AAR +A+PGD VLLAPAGASFDQF+ Sbjct 420 VHGTTESAVNHVTRVI--DTGGRPLPDAVMRAAVDAARHLARPGDAVLLAPAGASFDQFS 477 Query 469 GYADRGEAFATAVRA 483 GY RG+AFA AVRA Sbjct 478 GYTQRGDAFAAAVRA 492 >gi|108800224|ref|YP_640421.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium sp. MCS] gi|119869352|ref|YP_939304.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium sp. KMS] gi|108770643|gb|ABG09365.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium sp. MCS] gi|119695441|gb|ABL92514.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium sp. KMS] Length=495 Score = 504 bits (1298), Expect = 1e-140, Method: Compositional matrix adjust. Identities = 328/495 (67%), Positives = 371/495 (75%), Gaps = 19/495 (3%) Query 1 VLDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLR----PHAERGLPTVS 56 V++PL PG VL+ G +TG++V+AVL G T+CDDDP+ L+ P A V+ Sbjct 5 VVEPLTPGVRVLITGAGLTGRSVSAVLEPTGVRLTICDDDPLALQRLITPAA-----VVT 59 Query 57 SSDAVQQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWL 116 + +AV I YALVV SPGF P P+LAAAAAAGVPIWGDVELAWRLD AG +GPPR WL Sbjct 60 TGEAVAGIADYALVVTSPGFPPTAPVLAAAAAAGVPIWGDVELAWRLDRAGWFGPPRRWL 119 Query 117 VVTGTNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVL--------DEPAELLAVELS 168 VVTGTNGKTTTTSML+A+L A RRA+LCGNIG+ VLDVL DE ELLAVELS Sbjct 120 VVTGTNGKTTTTSMLYAILRAADRRAMLCGNIGNPVLDVLGESPRTRGDEEPELLAVELS 179 Query 169 SFQLHWAPSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALL 228 SFQLHWAPSLRP+AG VLN+AEDHLDWH +M Y KAR L G VAVAGLDD AA LL Sbjct 180 SFQLHWAPSLRPDAGVVLNVAEDHLDWHGSMTAYARDKARALDGRVAVAGLDDPVAAELL 239 Query 229 DGSPAQVRVGFRLGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAA 288 + A VRVGFRLG P A ELGV D LVD AF+D L L I V GPVGVL+ALAAA Sbjct 240 TTAAAPVRVGFRLGPPGAGELGVHDGWLVDNAFADGLRLARADDIRVAGPVGVLNALAAA 299 Query 289 ALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRV 348 ALAR+V VPA A+A A+ SF VGRHRAEVVAV+ G+T+VDDSKATNPHAARAS+ AYPRV Sbjct 300 ALARAVDVPAEAVAAALASFEVGRHRAEVVAVSGGVTWVDDSKATNPHAARASIAAYPRV 359 Query 349 VWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTG 408 VWIAGGLLKG S+ A VA +A RL G VLIGRDRA VAEALSRHAPDVPVV++V GED+G Sbjct 360 VWIAGGLLKGVSVDALVAEVADRLAGVVLIGRDRAVVAEALSRHAPDVPVVELVTGEDSG 419 Query 409 MPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFT 468 + T E V V V D G + AVM AAV AAR +A+PGD VLLAPAGASFDQF+ Sbjct 420 VHGTTESAVNHVTRVI--DTGGRPLPDAVMRAAVDAARHLARPGDAVLLAPAGASFDQFS 477 Query 469 GYADRGEAFATAVRA 483 GY RG+AFA AVRA Sbjct 478 GYTQRGDAFAAAVRA 492 >gi|120404497|ref|YP_954326.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium vanbaalenii PYR-1] gi|158513018|sp|A1TAX0.1|MURD_MYCVP RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|119957315|gb|ABM14320.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Mycobacterium vanbaalenii PYR-1] Length=483 Score = 493 bits (1268), Expect = 4e-137, Method: Compositional matrix adjust. Identities = 321/485 (67%), Positives = 365/485 (76%), Gaps = 2/485 (0%) Query 2 LDPLGPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV 61 + P+ PGA VLV G +TG+AV A L GA T+ DD P L A++ + + + AV Sbjct 1 MQPISPGAAVLVVGAGITGRAVLAALAPLGARATLTDDSPTALTASAQQRVEVLDPATAV 60 Query 62 QQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGT 121 +I + LVV SPG P P+ AAAAAG+P+WGDVELAW LD +G +GPPR WLVVTGT Sbjct 61 DRIADFDLVVVSPGIPPTAPIPVAAAAAGIPVWGDVELAWHLDRSGRFGPPRQWLVVTGT 120 Query 122 NGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPE 181 NGKTTTTSML+AML AGGRRAVLCGNIG VL LD PA++LAVELSSFQLHWAPSLRPE Sbjct 121 NGKTTTTSMLYAMLQAGGRRAVLCGNIGDPVLSQLDRPADVLAVELSSFQLHWAPSLRPE 180 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 AGAVLN+AEDHLDWH +MA Y KAR LTG VAV GLDD+ AA LL +PA V+VGFRL Sbjct 181 AGAVLNVAEDHLDWHGSMAAYAGDKARALTGRVAVGGLDDAIAAGLLADAPAPVKVGFRL 240 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 G+P E GVRD L+D AF DL L +IPV GPVGVLDALAAAALAR+V VPA AI Sbjct 241 GDPGPGEFGVRDGVLIDNAFGRDLALADADTIPVAGPVGVLDALAAAALARAVDVPAAAI 300 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 A+A+ +F VGRHRAEVVAVADGITYVDDSKATNPHAA+ASV A+PRVVW+AGGLLKGAS+ Sbjct 301 AEALATFHVGRHRAEVVAVADGITYVDDSKATNPHAAQASVSAFPRVVWVAGGLLKGASV 360 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 V A RLVG VLIGRDRA V ALSRHAPDVPVV++V GED+ + E V V Sbjct 361 DEMVEATKDRLVGVVLIGRDRAIVGNALSRHAPDVPVVELVTGEDSVVLEKDESGVTRVT 420 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAV 481 V + T+ AVMTAAV AAR +A GDTVLLAPAGASFDQFTGY RG+AFA AV Sbjct 421 RVIQ--TGDRTLADAVMTAAVDAARGLATSGDTVLLAPAGASFDQFTGYGHRGDAFAAAV 478 Query 482 RAVIR 486 RA IR Sbjct 479 RAAIR 483 >gi|169629091|ref|YP_001702740.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Mycobacterium abscessus ATCC 19977] gi|169241058|emb|CAM62086.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase MurD [Mycobacterium abscessus] Length=488 Score = 454 bits (1168), Expect = 2e-125, Method: Compositional matrix adjust. Identities = 293/483 (61%), Positives = 344/483 (72%), Gaps = 8/483 (1%) Query 5 LGPGAPVLVAGGRVTGQAVAAVLT---RFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV 61 L G VLV G RVTG AV A LT G TVCDDD L+ H + G ++++ A Sbjct 9 LTGGTRVLVCGARVTGDAVVAALTGLADLGLRITVCDDDEDALQRHRDAGHGALTTAAAQ 68 Query 62 QQITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGT 121 + + LV+ SPGF P+ P++ AA AG+PIWGDVELAWRLDA+G YG P+ W+VVTGT Sbjct 69 RHMADQDLVIVSPGFGPSAPVVQAAVQAGLPIWGDVELAWRLDASGRYGRPKRWVVVTGT 128 Query 122 NGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPE 181 NGKTTTT+M+H ML A G + LCGNIG VL+VLD E LAVELSSFQLHWAPS+RP Sbjct 129 NGKTTTTAMVHDMLTAAGGTSALCGNIGDPVLNVLDRDVEFLAVELSSFQLHWAPSVRPV 188 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 AGAVLN+AEDHLDWH M YT KAR L G VAVAGLDD+ A LL + A V+ GFR Sbjct 189 AGAVLNVAEDHLDWHGGMEGYTRDKARALDGEVAVAGLDDAIAGGLLAAAAAPVKAGFRA 248 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 GEPA ELGV D LVDRAF D+ L+ V+ +PV GP+GVL+ALAAAALAR+VG PA I Sbjct 249 GEPAVGELGVLDGWLVDRAFGVDIPLIEVSKLPVGGPIGVLNALAAAALARAVGTPAVHI 308 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 A A+ F+VGRHRAE++A + YVDDSKATNPHAA AS+ YPRVVWIAGGLLKGA++ Sbjct 309 ARALEVFQVGRHRAELIARVADVAYVDDSKATNPHAAAASIAGYPRVVWIAGGLLKGAAV 368 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 V A RL VLIGRDRA +AEAL+RHAPDVPVV VV ED G+ E V V Sbjct 369 DDLVRDCADRLGAVVLIGRDRALIAEALARHAPDVPVVAVVTREDAGVQ---EANVVYVT 425 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAV 481 D A D G +G VM AAV A +A+PGDTVLLAPAGASFDQF+GY++RG+ FA AV Sbjct 426 DEA--DGGGADLGTRVMAAAVRHASSLARPGDTVLLAPAGASFDQFSGYSERGDRFAAAV 483 Query 482 RAV 484 A+ Sbjct 484 HAL 486 >gi|111018103|ref|YP_701075.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Rhodococcus jostii RHA1] gi|118595686|sp|Q0SHR9.1|MURD_RHOSR RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|110817633|gb|ABG92917.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Rhodococcus jostii RHA1] Length=499 Score = 411 bits (1057), Expect = 1e-112, Method: Compositional matrix adjust. Identities = 270/480 (57%), Positives = 319/480 (67%), Gaps = 12/480 (2%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV---QQI 64 G VLVAG V+G+A L GA TV D + L A G TV D + ++ Sbjct 13 GRSVLVAGAGVSGRATIEPLRDLGALVTVTDANVDALAECARLGAATVPIDDLLAERDRV 72 Query 65 TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGK 124 +ALVV SPGF P PLL+ AA GVPIWGD+E +W +D AG YGPPR WLVVTGTNGK Sbjct 73 AEFALVVTSPGFRPDAPLLSLAAGDGVPIWGDIEFSWHVDRAGLYGPPRRWLVVTGTNGK 132 Query 125 TTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVL--DEP-AELLAVELSSFQLHWAPSLRPE 181 TTTTSML ++L A ++ CGNIG VLD L EP AE LAVELSSFQLHWAPS+RP Sbjct 133 TTTTSMLQSILEAAELPSLACGNIGIPVLDALRQTEPRAEALAVELSSFQLHWAPSVRPT 192 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 AGA+LNIAEDHLDWH M Y AKAR LTG VAV GLDD A++L SPA VGFRL Sbjct 193 AGAILNIAEDHLDWHGGMQPYIDAKARALTGEVAVLGLDDEVASSLFSSSPAVRTVGFRL 252 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 G PA ELGV D +LVDRAF+D L P I PGP G++DALAAAALAR++GVP A+ Sbjct 253 GVPAPGELGVEDGYLVDRAFADGERLAPAEGITPPGPAGLMDALAAAALARAIGVPPDAV 312 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 A + + VG HRA +VA G+T+VDDSKATNPHAAR S+LA+ RVVWIAGGLLKGA + Sbjct 313 AAGLAAHVVGPHRAALVAEVGGVTFVDDSKATNPHAARPSILAHERVVWIAGGLLKGARV 372 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 V +ASRL GAVL+GRD +AE+L+RHAP+VPVV V G+D G+ A + V+ Sbjct 373 DDLVREVASRLAGAVLLGRDAMQIAESLARHAPEVPVVTVETGDDAGVSAVPQTATHRVV 432 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAV 481 A D AVM V A +A GD+V+LAPA AS D F Y RG++F AV Sbjct 433 LPADTDS------DAVMGVVVREAAALATAGDSVVLAPAAASLDMFASYGHRGDSFTDAV 486 >gi|312140144|ref|YP_004007480.1| UDP-N-acetylmuramoyl-l-alanine-d-glutamate ligase murd [Rhodococcus equi 103S] gi|311889483|emb|CBH48800.1| UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase MurD [Rhodococcus equi 103S] Length=503 Score = 400 bits (1029), Expect = 2e-109, Method: Compositional matrix adjust. Identities = 273/480 (57%), Positives = 319/480 (67%), Gaps = 17/480 (3%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV---QQI 64 GA VLV G ++G+AV A L GA TV D L AE G TV D +++ Sbjct 13 GARVLVTGAGISGRAVIAPLHDLGAHVTVTDTAADALARCAEAGASTVPVDDLAADPRRM 72 Query 65 TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGK 124 + LVV SPGF P P+LAAAAAAGVP+WGD+E W +D +G YGPPR WLVVTGTNGK Sbjct 73 AEFELVVTSPGFRPDAPVLAAAAAAGVPVWGDIEFTWHVDRSGMYGPPRQWLVVTGTNGK 132 Query 125 TTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLD-EP-AELLAVELSSFQLHWAPSLRPEA 182 TTTTSMLH++L A G + CGNIG VLD L +P AE+LAVELSSFQLHWAPS+RP A Sbjct 133 TTTTSMLHSILEAAGFVSAACGNIGLPVLDALRAQPRAEVLAVELSSFQLHWAPSVRPAA 192 Query 183 GAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLG 242 G VLNIAEDHLDWH M Y AKA+ LTG VAV GLDD AA+L D S +GFRLG Sbjct 193 GVVLNIAEDHLDWHGGMPGYVDAKAQALTGAVAVVGLDDPVAASLADRSRDGRTIGFRLG 252 Query 243 EPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIA 302 EP ELGV D LVDRAF+D L+P I PGP GV DALAAAALAR++GV A+A Sbjct 253 EPDPNELGVVDGVLVDRAFADGAALVPADEISPPGPAGVSDALAAAALARAIGVTTDAVA 312 Query 303 DAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLH 362 + + RVG HRA+VV IT+VDDSKATNPHAAR+S++A+ VVWIAGGLLKGA + Sbjct 313 AGLRAHRVGPHRAQVVRTLAEITFVDDSKATNPHAARSSIVAHDSVVWIAGGLLKGARVD 372 Query 363 AEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPV----- 417 VA + R+ GAVLIGRD A+A+AL+RHAP+VPVV V AG+D G V+ P Sbjct 373 DLVAEVGERIAGAVLIGRDAGAIADALARHAPEVPVVLVRAGDDGGHEG-VDGPEEGADP 431 Query 418 ACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAF 477 A LD+ D VM AV A +A PGD VLLAPA AS D F Y RG +F Sbjct 432 ALHLDLPAADA------DTVMAEAVRTAAALAAPGDVVLLAPAAASLDMFDSYGHRGRSF 485 >gi|226307041|ref|YP_002767001.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Rhodococcus erythropolis PR4] gi|226186158|dbj|BAH34262.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Rhodococcus erythropolis PR4] Length=507 Score = 399 bits (1026), Expect = 5e-109, Method: Compositional matrix adjust. Identities = 259/483 (54%), Positives = 312/483 (65%), Gaps = 12/483 (2%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERG---LPTVSSSDAVQQI 64 G VLVAGGRV+GQA L GA TV D + AE G + T S DA I Sbjct 16 GTRVLVAGGRVSGQATIEPLVALGAVVTVADSTLDFAQRCAELGADMVTTTSIEDAPDSI 75 Query 65 TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGK 124 T Y LVV SPGF P P+LAAAA G+PIWGDVE +WR+D +G +G PR WLVVTGTNGK Sbjct 76 TEYGLVVTSPGFRPDAPILAAAAGHGIPIWGDVEFSWRVDHSGHFGGPRKWLVVTGTNGK 135 Query 125 TTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPA---ELLAVELSSFQLHWAPSLRPE 181 TTTTSML ++L A G CGNIG +LD L E + E LAVELSSFQLHWAPS+RP+ Sbjct 136 TTTTSMLASILDAAGVVGRACGNIGLPILDALAETSPRVEYLAVELSSFQLHWAPSVRPD 195 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 AG VLN+AEDHLDWH M+ Y AK+R L+G VAV GLDD+ A+ L + A + GFRL Sbjct 196 AGVVLNVAEDHLDWHGGMSAYAEAKSRALSGKVAVVGLDDAIASELGTRATADIVTGFRL 255 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 GEP ELGV HLVD AF D + L ASI GP GV+DALAAAALAR++G A + Sbjct 256 GEPGEGELGVEAGHLVDNAFGDHVRLAEAASIDPAGPAGVMDALAAAALARALGFEADVV 315 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 + + +VG HR +V + Y+DDSKATNPHAAR S+LA+ RVVW+AGGLLKGAS+ Sbjct 316 ERGLAAHKVGPHRGALVGRVGSVVYIDDSKATNPHAARPSILAHDRVVWVAGGLLKGASV 375 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 V+ + RL GAVL+GRD + +AL+RHAPDVPVV V++G+D A E L Sbjct 376 EQLVSEVGPRLSGAVLLGRDAGVIEDALARHAPDVPVVHVLSGDDE---AVSENSSNSTL 432 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAV 481 + AVM A V A +A PGD V+LAPA AS D F Y RG++F AV Sbjct 433 TIRLPSG---ADADAVMAAVVVEAAELASPGDAVVLAPAAASLDMFASYGHRGDSFTAAV 489 Query 482 RAV 484 A+ Sbjct 490 AAL 492 >gi|325676975|ref|ZP_08156647.1| UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase [Rhodococcus equi ATCC 33707] gi|325552275|gb|EGD21965.1| UDP-N-acetylmuramoyl-L-alanine-D-glutamate ligase [Rhodococcus equi ATCC 33707] Length=503 Score = 399 bits (1024), Expect = 9e-109, Method: Compositional matrix adjust. Identities = 272/480 (57%), Positives = 318/480 (67%), Gaps = 17/480 (3%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV---QQI 64 GA VLV G ++G+AV A L GA TV D L AE G TV D +++ Sbjct 13 GARVLVTGAGISGRAVIAPLHDLGAHVTVTDTAADALARCAEAGASTVPVDDLAADPRRM 72 Query 65 TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGK 124 + LVV SPGF P P+LAAAAAAGVP+WGD+E W +D +G YGPPR WLVVTGTNGK Sbjct 73 AEFELVVTSPGFRPDAPVLAAAAAAGVPVWGDIEFTWHVDRSGMYGPPRQWLVVTGTNGK 132 Query 125 TTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLD-EP-AELLAVELSSFQLHWAPSLRPEA 182 TTTTSMLH++L A G + CGNIG VLD L +P AE+LAVELSSFQLHWAPS+RP A Sbjct 133 TTTTSMLHSILEAAGFVSAACGNIGLPVLDALRAQPRAEVLAVELSSFQLHWAPSVRPAA 192 Query 183 GAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLG 242 G VLNIAEDHLDWH M Y AKA+ LTG VAV GLDD AA+L D +GFRLG Sbjct 193 GVVLNIAEDHLDWHGGMPGYIDAKAQALTGAVAVVGLDDPVAASLADRPRDGRTIGFRLG 252 Query 243 EPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIA 302 EP ELGV D LVDRAF+D L+P I PGP GV DALAAAALAR++GV A+A Sbjct 253 EPDPNELGVVDGVLVDRAFADGAALVPADEISPPGPAGVSDALAAAALARAIGVTTDAVA 312 Query 303 DAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLH 362 + + RVG HRA+VV IT+VDDSKATNPHAAR+S++A+ VVWIAGGLLKGA + Sbjct 313 AGLRAHRVGPHRAQVVRTLAEITFVDDSKATNPHAARSSIVAHDSVVWIAGGLLKGARVD 372 Query 363 AEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPV----- 417 VA + R+ GAVLIGRD A+A+AL+RHAP+VPVV V AG+D G V+ P Sbjct 373 DLVAEVGERIAGAVLIGRDAGAIADALARHAPEVPVVLVRAGDDGGHEG-VDGPEEGADP 431 Query 418 ACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAF 477 A LD+ D VM AV A +A PGD VLLAPA AS D F Y RG +F Sbjct 432 ALHLDLPAADA------DTVMAEAVRTAAALAAPGDVVLLAPAAASLDMFDSYGHRGRSF 485 >gi|229490474|ref|ZP_04384315.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Rhodococcus erythropolis SK121] gi|229322764|gb|EEN88544.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Rhodococcus erythropolis SK121] Length=507 Score = 397 bits (1021), Expect = 2e-108, Method: Compositional matrix adjust. Identities = 258/490 (53%), Positives = 312/490 (64%), Gaps = 26/490 (5%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERG---LPTVSSSDAVQQI 64 G VLVAGGRV+GQA L GA TV D AE G + T S DA I Sbjct 16 GTRVLVAGGRVSGQATIEPLVALGAVVTVADSTLDFAERCAELGADMVTTTSIEDAPDSI 75 Query 65 TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGK 124 T Y LVV SPGF P P+LAAAA G+PIWGDVE +WR+D +G +G PR WLVVTGTNGK Sbjct 76 TEYGLVVTSPGFRPDAPILAAAAGHGIPIWGDVEFSWRVDHSGHFGTPRKWLVVTGTNGK 135 Query 125 TTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPA---ELLAVELSSFQLHWAPSLRPE 181 TTTTSML ++L G CGNIG +LD L E + E LAVELSSFQLHWAPS+RP+ Sbjct 136 TTTTSMLASILDGAGVVGRACGNIGLPILDALAETSPRVEYLAVELSSFQLHWAPSVRPD 195 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 AG VLN+AEDHLDWH M+ Y AK+R L+G VAV GLDD+ A+ L + A + GFRL Sbjct 196 AGVVLNVAEDHLDWHGGMSAYAEAKSRALSGRVAVVGLDDAIASELGTRATADIVTGFRL 255 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 GEP ELGV HLVD AF D + L ASI GP GV+DALAAAALAR++G A + Sbjct 256 GEPGEGELGVEAGHLVDNAFGDHVRLAEAASIDPAGPAGVMDALAAAALARALGFEADVV 315 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 + + +VG HR +V + Y+DDSKATNPHAAR S+LA+ RVVW+AGGLLKGAS+ Sbjct 316 ERGLAAHKVGPHRGALVGRVGSVVYIDDSKATNPHAARPSILAHDRVVWVAGGLLKGASV 375 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGED-------TGMPATVE 414 V+ + RL GAVL+GRD + +AL+RHAPDVPVV V++G+D + T+ Sbjct 376 DQLVSEVGPRLSGAVLLGRDAGVIEDALARHAPDVPVVHVMSGDDAVVSENSSNSTLTIR 435 Query 415 VPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRG 474 +P AVM A V A +A PGD V+LAPA AS D F Y RG Sbjct 436 LPSGADA-------------DAVMAAVVVEAAELASPGDAVVLAPAAASLDMFASYGHRG 482 Query 475 EAFATAVRAV 484 ++FA AV A+ Sbjct 483 DSFAAAVAAL 492 >gi|226360232|ref|YP_002778010.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Rhodococcus opacus B4] gi|226238717|dbj|BAH49065.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Rhodococcus opacus B4] Length=499 Score = 397 bits (1020), Expect = 2e-108, Method: Compositional matrix adjust. Identities = 270/480 (57%), Positives = 320/480 (67%), Gaps = 12/480 (2%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAV---QQI 64 G VLVAG V+G+A L GA TV D + L A RG TV D + +++ Sbjct 13 GRSVLVAGAGVSGRATIEPLRDLGAHVTVTDSNVDALAECARRGAATVPIDDLLAEREKV 72 Query 65 TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGK 124 +ALVV SPGF P PLL+AAA GVPIWGD+E +W +D AG YGPPR WLVVTGTNGK Sbjct 73 AEFALVVTSPGFRPDAPLLSAAAGDGVPIWGDIEFSWHVDRAGLYGPPRRWLVVTGTNGK 132 Query 125 TTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEP---AELLAVELSSFQLHWAPSLRPE 181 TTTTSML ++L A G ++ CGNIG VLD L AE+LAVELSSFQLHWAPS+RP Sbjct 133 TTTTSMLQSILEAAGLPSLACGNIGLPVLDALRPTGPRAEVLAVELSSFQLHWAPSVRPT 192 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRL 241 AGA+LNIAEDHLDWH M Y AKAR LTG VAV GLDD A++L S A +GFRL Sbjct 193 AGAILNIAEDHLDWHGGMQPYIDAKARALTGEVAVLGLDDEVASSLFSSSLAVRTLGFRL 252 Query 242 GEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAI 301 G PAA ELGV D +LVDRAF+D L P I PGP G++DALAAAALAR++GVP A+ Sbjct 253 GVPAAGELGVEDGYLVDRAFADGERLAPADGITPPGPAGLMDALAAAALARAIGVPPDAV 312 Query 302 ADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASL 361 A + + VG HRA VA G+T+VDDSKATNPHAAR S+LA+ RVVWIAGGLLKGA + Sbjct 313 AAGLAAHVVGPHRAARVAEVGGVTFVDDSKATNPHAARPSILAHDRVVWIAGGLLKGARV 372 Query 362 HAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVL 421 V +A RL GAVL+GRD +AE+L+RHAP+VPVV V G+D G+ A + V+ Sbjct 373 DDLVREVAGRLAGAVLLGRDARQIAESLARHAPEVPVVTVETGDDAGVSAVPQTATHRVV 432 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAV 481 A +T AVM V A +A GD V+LAPA AS D F Y RG +FA AV Sbjct 433 ------LAADTDSDAVMGVVVREAAALASAGDAVVLAPAAASLDMFDSYGHRGRSFAVAV 486 >gi|296140344|ref|YP_003647587.1| UDP-N-acetylmuramoylalanine/D-glutamate ligase [Tsukamurella paurometabola DSM 20162] gi|296028478|gb|ADG79248.1| UDP-N-acetylmuramoylalanine/D-glutamate ligase [Tsukamurella paurometabola DSM 20162] Length=486 Score = 384 bits (986), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 263/480 (55%), Positives = 314/480 (66%), Gaps = 18/480 (3%) Query 6 GPGAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQ-QI 64 GPGA VLVAGG VTG AVA L R GA TV D PV R +P V+ D Sbjct 6 GPGAHVLVAGGGVTGPAVARALLRLGAAVTVADGKPVA-REKIAAEVPEVAVVDLDDLDP 64 Query 65 TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGK 124 GYALVV +PGF P P++ AA AGVP+ GDVELAW +D AG +G PR WLVVTGTNGK Sbjct 65 AGYALVVVAPGFRPTAPIVVAAQDAGVPVIGDVELAWWIDRAGAFGAPRDWLVVTGTNGK 124 Query 125 TTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAE--LLAVELSSFQLHWAPSLRPEA 182 TTTT ML ++L G AV CGNIG V+D + + A+ +LAVELSSFQLHWAPS+RP A Sbjct 125 TTTTQMLESILAHAGLPAVACGNIGRPVIDAIADAADPRVLAVELSSFQLHWAPSVRPRA 184 Query 183 GAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLG 242 G VLNIAEDHLDWH +MA YTA KAR LTG +AV GLDD AA L PA GF +G Sbjct 185 GVVLNIAEDHLDWHGSMAAYTADKARALTGDIAVVGLDDPVAATL----PAAT--GFTVG 238 Query 243 EPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIA 302 EPA + GVR L+D A S +++P A + PGP G+ DALAA ALA++VGV A Sbjct 239 EPAPGQYGVRAGMLIDGAGS---SIVPAARVSPPGPAGIADALAATALAQAVGVTAAQAG 295 Query 303 DAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLH 362 A+T FRVG HRAE VA G+TY+DDSKATNPHAA+ S+ A+ RVVW+AGG LKGA + Sbjct 296 AALTQFRVGAHRAEPVATVRGVTYIDDSKATNPHAAQNSIEAHERVVWVAGGQLKGADID 355 Query 363 AEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGM-PATVEVPVACVL 421 VA +ASRL GAVL+G D +A A++RHAPDVPVV+V +G+D+ + P T + + Sbjct 356 PLVARVASRLAGAVLLGVDAELIAAAMARHAPDVPVVRVTSGDDSRVSPVTNDASRSIGT 415 Query 422 DVAKDDKAGETVGAAVMTAAVAAARRMAQPGDT----VLLAPAGASFDQFTGYADRGEAF 477 VA D + A + A AAA G + VLLAPA AS D F Y RGEAF Sbjct 416 SVAGDVRVSGDADAVMTAAVHAAAGLADVAGQSRTPVVLLAPAAASLDMFRSYGHRGEAF 475 >gi|118595670|sp|Q5YYY1.2|MURD_NOCFA RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase Length=480 Score = 363 bits (931), Expect = 5e-98, Method: Compositional matrix adjust. Identities = 250/480 (53%), Positives = 305/480 (64%), Gaps = 18/480 (3%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQ-QITG 66 G VLVAG ++G+++ L GA P V D L AE GL +S + ++ Sbjct 7 GRDVLVAGWGISGRSLVEPLRDIGAHPVVTDSGAKALAEAAELGLEVATSVELESADLSR 66 Query 67 YALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGKTT 126 +ALV+ SPG+ P +P+L +A G+P+WGDVE AW +D A YGP R WLVVTGTNGKTT Sbjct 67 FALVITSPGWRPDSPVLVSAVTEGIPVWGDVEFAWWVDQARIYGPVRKWLVVTGTNGKTT 126 Query 127 TTSMLHAMLIAGGRRAVLCGNIGSAVLDVL--DEPAELLAVELSSFQLHWAPSLRPEAGA 184 TT M HA+L A G +V CGNIG +LD L + ++LAVELSSFQLHWAPS+RPEAG Sbjct 127 TTQMTHAILRAAGIASVACGNIGLPILDALRRNPGPQVLAVELSSFQLHWAPSVRPEAGV 186 Query 185 VLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLGEP 244 VLN+AEDHLDWH + Y AAKAR L G + V GLDD AAAL S A+ VGFR+G P Sbjct 187 VLNVAEDHLDWHGGLDAYAAAKARALVGRIGVVGLDDPVAAALARRSKARRTVGFRVGVP 246 Query 245 AARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIADA 304 A ELGV D L+DRAF+ L V I PGP GV DALAAAAL R++ V + + Sbjct 247 ADGELGVVDGKLLDRAFTKAAILAEVGDISPPGPAGVADALAAAALTRAIDVAPQFVKEG 306 Query 305 VTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLHAE 364 + +VG HRA V G+ ++DDSKATNPHAAR+S+LA+P VVWIAGG LKGA++ Sbjct 307 LQEHKVGPHRAAFVREVAGVEFIDDSKATNPHAARSSILAHPHVVWIAGGRLKGAAVEDL 366 Query 365 VAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVLDVA 424 V +A RLV AVLIG D +A AL+RHAP+VPVV+V AG+D M Sbjct 367 VEEVADRLVAAVLIGVDAPVIAAALARHAPEVPVVEVRAGDDAVM--------------- 411 Query 425 KDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAVRAV 484 DD AVM AAV A A+ GDTVLLAPA AS D F Y RG +FA AV A+ Sbjct 412 ADDPLRPDEADAVMAAAVRTAAGYARAGDTVLLAPAAASLDMFADYTHRGRSFADAVHAL 471 >gi|54023732|ref|YP_117974.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Nocardia farcinica IFM 10152] gi|54015240|dbj|BAD56610.1| putative UDP-N-acetylmuramoylalanine-D- glutamate ligase [Nocardia farcinica IFM 10152] Length=497 Score = 362 bits (930), Expect = 6e-98, Method: Compositional matrix adjust. Identities = 250/480 (53%), Positives = 305/480 (64%), Gaps = 18/480 (3%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQ-QITG 66 G VLVAG ++G+++ L GA P V D L AE GL +S + ++ Sbjct 24 GRDVLVAGWGISGRSLVEPLRDIGAHPVVTDSGAKALAEAAELGLEVATSVELESADLSR 83 Query 67 YALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGKTT 126 +ALV+ SPG+ P +P+L +A G+P+WGDVE AW +D A YGP R WLVVTGTNGKTT Sbjct 84 FALVITSPGWRPDSPVLVSAVTEGIPVWGDVEFAWWVDQARIYGPVRKWLVVTGTNGKTT 143 Query 127 TTSMLHAMLIAGGRRAVLCGNIGSAVLDVL--DEPAELLAVELSSFQLHWAPSLRPEAGA 184 TT M HA+L A G +V CGNIG +LD L + ++LAVELSSFQLHWAPS+RPEAG Sbjct 144 TTQMTHAILRAAGIASVACGNIGLPILDALRRNPGPQVLAVELSSFQLHWAPSVRPEAGV 203 Query 185 VLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQVRVGFRLGEP 244 VLN+AEDHLDWH + Y AAKAR L G + V GLDD AAAL S A+ VGFR+G P Sbjct 204 VLNVAEDHLDWHGGLDAYAAAKARALVGRIGVVGLDDPVAAALARRSKARRTVGFRVGVP 263 Query 245 AARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIADA 304 A ELGV D L+DRAF+ L V I PGP GV DALAAAAL R++ V + + Sbjct 264 ADGELGVVDGKLLDRAFTKAAILAEVGDISPPGPAGVADALAAAALTRAIDVAPQFVKEG 323 Query 305 VTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLHAE 364 + +VG HRA V G+ ++DDSKATNPHAAR+S+LA+P VVWIAGG LKGA++ Sbjct 324 LQEHKVGPHRAAFVREVAGVEFIDDSKATNPHAARSSILAHPHVVWIAGGRLKGAAVEDL 383 Query 365 VAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVLDVA 424 V +A RLV AVLIG D +A AL+RHAP+VPVV+V AG+D M Sbjct 384 VEEVADRLVAAVLIGVDAPVIAAALARHAPEVPVVEVRAGDDAVM--------------- 428 Query 425 KDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFATAVRAV 484 DD AVM AAV A A+ GDTVLLAPA AS D F Y RG +FA AV A+ Sbjct 429 ADDPLRPDEADAVMAAAVRTAAGYARAGDTVLLAPAAASLDMFADYTHRGRSFADAVHAL 488 >gi|291003737|ref|ZP_06561710.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Saccharopolyspora erythraea NRRL 2338] Length=479 Score = 354 bits (908), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 246/493 (50%), Positives = 299/493 (61%), Gaps = 46/493 (9%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCD---DDPVMLRPHAERGLPTVSSSDAVQQI 64 G VLVAG V+G++ A L GA+ TV D D V L +G V + Sbjct 8 GLRVLVAGAGVSGRSAAEALLAAGASVTVSDASSDRLVALASLQAQGAELVPG--LTEPP 65 Query 65 TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGP---------PRSW 115 G LVV SPG+ P +PLLAA AAGV + G+VELAWRLD P P +W Sbjct 66 EGTDLVVTSPGWRPESPLLAATVAAGVELIGEVELAWRLDQEKANEPADSTGRPAGPATW 125 Query 116 LVVTGTNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWA 175 L VTGTNGKTTT ML ++L A G V CGN+G V+D + +LAVELSSFQLHW+ Sbjct 126 LAVTGTNGKTTTVGMLESILRADGVDVVACGNVGLPVVDAVRAGHRVLAVELSSFQLHWS 185 Query 176 PSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGG-VAVAGLDDSRAAALLD-GSPA 233 ++ P A VLN+A DHLDWH ++ Y AAKARV G VAV DD + L D G+P Sbjct 186 QTVAPHASVVLNLAADHLDWHGSLDAYGAAKARVYAGNSVAVHNADDEWSVRLADAGAPQ 245 Query 234 QVR-VGFRLGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALAR 292 Q R V F L +PA LGV LVDRAF D + L VA + GP V +ALAAA+LAR Sbjct 246 QARRVSFTLSDPAPGVLGVESGALVDRAFGDRVRLAAVADVHPAGPHNVANALAAASLAR 305 Query 293 SVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIA 352 + GV A+A+ + SF+ G HR+ VVA + G++YVDDSKATNPHAA A++ A+P+VVWIA Sbjct 306 AYGVEPEAVAEGLRSFQPGAHRSVVVAESAGVSYVDDSKATNPHAADAALRAHPKVVWIA 365 Query 353 GGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPAT 412 GGLLKGA + VAA A+RL G VLIGRDRA AEAL+RHAPDVPV +V +G+D GM A Sbjct 366 GGLLKGADVEDLVAANAARLAGVVLIGRDRARFAEALARHAPDVPVREVESGDDAGMLAA 425 Query 413 VEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYAD 472 V + AGE A+PG V+LAPA AS D FT YA Sbjct 426 VRL-------------AGE----------------FAEPGCAVVLAPAAASMDMFTDYAH 456 Query 473 RGEAFATAVRAVI 485 RG AFA AVR V+ Sbjct 457 RGRAFADAVRDVL 469 >gi|333918996|ref|YP_004492577.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Amycolicicoccus subflavus DQS3-9A1] gi|333481217|gb|AEF39777.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Amycolicicoccus subflavus DQS3-9A1] Length=527 Score = 353 bits (907), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 252/499 (51%), Positives = 312/499 (63%), Gaps = 22/499 (4%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAE---RGLPTVSSSDAVQQI 64 G VLVAG V+G A L GA V D L P E RGL S+ ++I Sbjct 16 GREVLVAGAGVSGLATVRALHAIGARAVVADTREHALEPAIEQGARGLLLDSAMPPGREI 75 Query 65 -TGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNG 123 G LVV SPG+ P LLA A G+P+WGDVELAWRLD AG +GPPR WL VTGTNG Sbjct 76 FEGIRLVVTSPGWRPDADLLAEATRNGIPVWGDVELAWRLDQAGIFGPPRRWLAVTGTNG 135 Query 124 KTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVL------DEP-----AELLAVELSSFQL 172 KTTTT+ML+++L A G + CGNIG +LD + D P ++LA+ELSSFQL Sbjct 136 KTTTTTMLNSILRAAGLHSAACGNIGRPILDAMMAGYGTDLPDLQARIDVLAIELSSFQL 195 Query 173 HWAPSLRPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSP 232 WAPS+ PEAG +LNIAEDHLDWH +M Y AK RVLTG + V GLDD A+ L + S Sbjct 196 FWAPSVTPEAGVILNIAEDHLDWHGSMDAYVEAKLRVLTGRIGVLGLDDPVASQLTNRSM 255 Query 233 AQVRVGFRLGEPAARELGVRDAHLVDRAFSD--DLTLLPVASIPVPGPVGVLDALAAAAL 290 A +GFRLG P E GV D +LVDRAF D + L+ + G G+LD LAAAAL Sbjct 256 AARTIGFRLGAPERNEFGVADGYLVDRAFGDAAGVRLVKADEVRPGGRPGLLDGLAAAAL 315 Query 291 ARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVW 350 AR +GV A A+A+ + + G HR VA G+TYVDDSKATNPHAA AS+ YPRVVW Sbjct 316 ARGLGVAAEAVAEGLRTHETGPHRNAKVASLGGVTYVDDSKATNPHAALASISTYPRVVW 375 Query 351 IAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMP 410 +AGGLLKGA++ +A + +LV AVLIG DR +AE L+RHAPDVPVV+V AG+D + Sbjct 376 LAGGLLKGANVEELIADVRDQLVAAVLIGADRRVIAETLARHAPDVPVVEVFAGDDRSVT 435 Query 411 -ATVEVPVACVLDVAKDDKAGETVGAAV----MTAAVAAARRMAQPGDTVLLAPAGASFD 465 T++ A A++ + V + M AV AA +A+ GDTVLLAP+ AS D Sbjct 436 VTTIQSGRAGTPLAAQEKRYAAPVDTDLADAVMARAVNAAAALARRGDTVLLAPSAASLD 495 Query 466 QFTGYADRGEAFATAVRAV 484 F Y RG +F+ AV A+ Sbjct 496 MFRDYGHRGRSFSLAVAAL 514 >gi|134102301|ref|YP_001107962.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Saccharopolyspora erythraea NRRL 2338] gi|133914924|emb|CAM05037.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Saccharopolyspora erythraea NRRL 2338] Length=469 Score = 353 bits (906), Expect = 4e-95, Method: Compositional matrix adjust. Identities = 244/490 (50%), Positives = 298/490 (61%), Gaps = 46/490 (9%) Query 11 VLVAGGRVTGQAVAAVLTRFGATPTVCD---DDPVMLRPHAERGLPTVSSSDAVQQITGY 67 +LVAG V+G++ A L GA+ TV D D V L +G V + G Sbjct 1 MLVAGAGVSGRSAAEALLAAGASVTVSDASSDRLVALASLQAQGAELVPG--LTEPPEGT 58 Query 68 ALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGP---------PRSWLVV 118 LVV SPG+ P +PLLAA AAGV + G+VELAWRLD P P +WL V Sbjct 59 DLVVTSPGWRPESPLLAATVAAGVELIGEVELAWRLDQEKANEPADSTGRPAGPATWLAV 118 Query 119 TGTNGKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSL 178 TGTNGKTTT ML ++L A G V CGN+G V+D + +LAVELSSFQLHW+ ++ Sbjct 119 TGTNGKTTTVGMLESILRADGVDVVACGNVGLPVVDAVRAGHRVLAVELSSFQLHWSQTV 178 Query 179 RPEAGAVLNIAEDHLDWHATMAEYTAAKARVLTGG-VAVAGLDDSRAAALLD-GSPAQVR 236 P A VLN+A DHLDWH ++ Y AAKARV G VAV DD + L D G+P Q R Sbjct 179 APHASVVLNLAADHLDWHGSLDAYGAAKARVYAGNSVAVHNADDEWSVRLADAGAPQQAR 238 Query 237 -VGFRLGEPAARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVG 295 V F L +PA LGV LVDRAF D + L VA + GP V +ALAAA+LAR+ G Sbjct 239 RVSFTLSDPAPGVLGVESGALVDRAFGDRVRLAAVADVHPAGPHNVANALAAASLARAYG 298 Query 296 VPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGL 355 V A+A+ + SF+ G HR+ VVA + G++YVDDSKATNPHAA A++ A+P+VVWIAGGL Sbjct 299 VEPEAVAEGLRSFQPGAHRSVVVAESAGVSYVDDSKATNPHAADAALRAHPKVVWIAGGL 358 Query 356 LKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEV 415 LKGA + VAA A+RL G VLIGRDRA AEAL+RHAPDVPV +V +G+D GM A V + Sbjct 359 LKGADVEDLVAANAARLAGVVLIGRDRARFAEALARHAPDVPVREVESGDDAGMLAAVRL 418 Query 416 PVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGE 475 AGE A+PG V+LAPA AS D FT YA RG Sbjct 419 -------------AGE----------------FAEPGCAVVLAPAAASMDMFTDYAHRGR 449 Query 476 AFATAVRAVI 485 AFA AVR V+ Sbjct 450 AFADAVRDVL 459 >gi|257056719|ref|YP_003134551.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Saccharomonospora viridis DSM 43017] gi|256586591|gb|ACU97724.1| UDP-N-acetylmuramoylalanine--D-glutamate ligase [Saccharomonospora viridis DSM 43017] Length=458 Score = 347 bits (891), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 242/488 (50%), Positives = 286/488 (59%), Gaps = 43/488 (8%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDDDPVMLRPHAERGLPTVSSSDAVQQITGY 67 G V VAG VTG++VA L GA TV D + L + G+ V D G Sbjct 5 GVAVCVAGAGVTGRSVATALVGMGAQVTVTDANAERLAELGDLGVRLVPGLDTPPD--GT 62 Query 68 ALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGP-PRSWLVVTGTNGKTT 126 LVV SPG+ P PLL AAA++G+ + GDVELAWR+ G P P +WL VTGTNGKTT Sbjct 63 RLVVTSPGWRPTAPLLTAAASSGIEVIGDVELAWRI---GQERPNPPTWLAVTGTNGKTT 119 Query 127 TTSMLHAMLIAGGRRAVLCGNIGSAVLDVLDEPAELLAVELSSFQLHWAPSLRPEAGAVL 186 T M +ML + G AV CGN+G AVLD + L VELSSFQLHW+ SL P A VL Sbjct 120 TVGMAESMLRSAGVDAVACGNVGFAVLDAVLAGHSTLVVELSSFQLHWSRSLAPSASVVL 179 Query 187 NIAEDHLDWHATMAEYTAAKARVLTG-GVAVAGLDD--SRAAALLDGSPAQVRVGFRLGE 243 N+AEDHLDWH +AEY A K + G G VA L D SR A P RVGF L Sbjct 180 NVAEDHLDWHGGLAEYAADKGTIHRGSGTVVANLRDPWSRKLAEEHAPPEARRVGFTLDT 239 Query 244 PAARELGVRDAHLVDRAFSDD-----LTLLPVASIPVPGPVGVLDALAAAALARSVGVPA 298 P ELGV + LVDRAF D L +A + GP V +ALAAAAL R+ GV Sbjct 240 PRPGELGVVEDLLVDRAFVADPVHAAEELGTLADVRPGGPHNVANALAAAALVRAYGVGP 299 Query 299 GAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKG 358 A+A+ + SFR G HRA V DG+ Y+DDSKATNPHAA S+LA+P VVWIAGG LKG Sbjct 300 EAVAEGLRSFRPGAHRAVEVGEFDGVRYIDDSKATNPHAAIGSLLAHPSVVWIAGGQLKG 359 Query 359 ASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVA 418 AS+ VAA+A RL G VL+G D AEAL+RHAPDV V ++ +G+D Sbjct 360 ASVDELVAAVAERLRGVVLLGADADVFAEALARHAPDVLVRRIGSGDDE----------- 408 Query 419 CVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFTGYADRGEAFA 478 MTAAV AAR +A+PGD VLLAPA AS D F YA+RGEAFA Sbjct 409 ------------------PMTAAVKAARELARPGDAVLLAPAAASLDMFRDYAERGEAFA 450 Query 479 TAVRAVIR 486 AV + R Sbjct 451 AAVDELSR 458 >gi|29832662|ref|NP_827296.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Streptomyces avermitilis MA-4680] gi|60390553|sp|Q82AD8.1|MURD_STRAW RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|29609782|dbj|BAC73831.1| putative UDP-N-acetylmuramoylalanine-D- glutamate ligase [Streptomyces avermitilis MA-4680] Length=467 Score = 347 bits (890), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 242/496 (49%), Positives = 285/496 (58%), Gaps = 55/496 (11%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDD-DPVMLRPHA---ERGLPTVSSSDAVQQ 63 G V VAG V+G A VL GA TV +D D R A E TV D Sbjct 6 GKNVTVAGLGVSGIPAARVLHGLGAVVTVVNDGDDERSRAQAADLEALGITVRLGDGATL 65 Query 64 ITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNG 123 G L+V +PG+ P PL AAAA AGVP+WGDVELAWRL G WL VTGTNG Sbjct 66 PEGTELIVTTPGWQPDKPLFAAAAEAGVPVWGDVELAWRLRGPGSA----PWLAVTGTNG 121 Query 124 KTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVL--DEPAELLAVELSSFQLHWAPSLRPE 181 KTTT ML ++L A G R GNIG ++LD + +E ++LAVELSS+QLHWAPSLR Sbjct 122 KTTTVQMLASILTAAGLRTAAVGNIGVSLLDAVLGEETYDVLAVELSSYQLHWAPSLRAH 181 Query 182 AGAVLNIAEDHLDWHATMAEYTAAKARVLTGG-------VAVAGLDD-SRAAALLDGSPA 233 + VLNIA DHLDWH +M YTA K R+ G VA +D RAA + +G A Sbjct 182 SATVLNIAPDHLDWHGSMEAYTADKGRIYEGNRVACVYNVADKATEDLVRAADVEEGCRA 241 Query 234 QVRVGFRLGEPAARELGVRDAHLVDRAFSDD-----LTLLPVASIPVPGPVGVLDALAAA 288 VGF LG P +LGV + LVDRAF +D L VA + P P + +ALAAA Sbjct 242 ---VGFTLGTPGPSQLGVVEGILVDRAFVEDRQKNAQELAEVADVHPPAPHNIANALAAA 298 Query 289 ALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRV 348 ALAR+ GVPA A+ D + +FR HR VA DG+TY+DDSKATN HAA AS+ AY + Sbjct 299 ALARAFGVPASAVRDGLRAFRPDAHRIAHVADVDGVTYIDDSKATNTHAAEASLAAYGSI 358 Query 349 VWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTG 408 VWIAGGL KGAS VA A RL G VLIG DRA + EAL+RHAP+VPVV + + Sbjct 359 VWIAGGLAKGASFDELVAKSAQRLRGVVLIGADRALIREALARHAPEVPVVDLDRTDTGA 418 Query 409 MPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQFT 468 MP AAV ARR+A GDTVLLAPA AS D F Sbjct 419 MP-----------------------------AAVQEARRLAVAGDTVLLAPACASMDMFA 449 Query 469 GYADRGEAFATAVRAV 484 Y RG+AFA AVR + Sbjct 450 NYNKRGDAFAEAVRGL 465 >gi|21220566|ref|NP_626345.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Streptomyces coelicolor A3(2)] gi|289772189|ref|ZP_06531567.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase [Streptomyces lividans TK24] gi|30316144|sp|Q9S2W9.1|MURD_STRCO RecName: Full=UDP-N-acetylmuramoylalanine--D-glutamate ligase; AltName: Full=D-glutamic acid-adding enzyme; AltName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase gi|5689958|emb|CAB51995.1| putative UDP-N-acetylmuramoylalanine-D-glutamate ligase [Streptomyces coelicolor A3(2)] gi|289702388|gb|EFD69817.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase [Streptomyces lividans TK24] Length=471 Score = 343 bits (879), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 237/497 (48%), Positives = 284/497 (58%), Gaps = 54/497 (10%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPTVCDD-DPVMLRPHAERGLP---TVSSSDAVQQ 63 G V VAG V+G A VL GA TV +D D R A P TV D Sbjct 7 GKHVTVAGLGVSGVPAAKVLHGLGAQVTVVNDGDDERARTQAAELEPLGVTVRLGDGDTL 66 Query 64 ITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYG-PPRSWLVVTGTN 122 G L+V +PG+ P PL AA AGVP+WGDVELAWRL G G P WL VTGTN Sbjct 67 PEGTELIVTAPGWKPTKPLFTAAGQAGVPVWGDVELAWRL--RGLNGRKPAPWLAVTGTN 124 Query 123 GKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVL--DEPAELLAVELSSFQLHWAPSLRP 180 GKTTT ML ++L A G R GNIG ++LD + ++ ++LAVELSS+QLHWAPSLR Sbjct 125 GKTTTVQMLASILKAAGLRTAAVGNIGVSLLDAVTGEQEYDVLAVELSSYQLHWAPSLRA 184 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGG-------VAVAGLDD-SRAAALLDGSP 232 + AVLN+A DHLDWH +M Y A K R+ G VA +D RAA + +G Sbjct 185 HSAAVLNLAPDHLDWHGSMEAYAADKGRIYEGNHVACVYNVADKATEDLVRAADVEEGCR 244 Query 233 AQVRVGFRLGEPAARELGVRDAHLVDRAFSDD-----LTLLPVASIPVPGPVGVLDALAA 287 A +GF LG P +LGV + LVDRAF +D L V+ + P P + +ALAA Sbjct 245 A---IGFTLGTPGPSQLGVVEGLLVDRAFVEDRQKNAQELAEVSDVNPPAPHNIANALAA 301 Query 288 AALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPR 347 A LAR+ GV A A+ D + +F HR VA DG+ YVDDSKATN HA AS+ AY Sbjct 302 AGLARAFGVSAAAVRDGLRAFTPDAHRIAHVADVDGVAYVDDSKATNTHATEASLAAYES 361 Query 348 VVWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDT 407 +VWIAGGL KGA+ VA A RL GAVLIG DRA + EAL+RHAP+VPVV + DT Sbjct 362 IVWIAGGLAKGATFDELVAGAAKRLRGAVLIGADRALIREALARHAPEVPVVD-LDRTDT 420 Query 408 GMPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQF 467 G M AV ARR+A+PGDTVLLAPA AS D F Sbjct 421 G----------------------------AMLQAVQEARRLARPGDTVLLAPACASMDMF 452 Query 468 TGYADRGEAFATAVRAV 484 T Y RG+AFA AVR + Sbjct 453 TNYNQRGDAFAQAVREL 469 >gi|302518529|ref|ZP_07270871.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase [Streptomyces sp. SPB78] gi|302427424|gb|EFK99239.1| UDP-N-acetylmuramoylalanine-D-glutamate ligase [Streptomyces sp. SPB78] Length=474 Score = 342 bits (878), Expect = 6e-92, Method: Compositional matrix adjust. Identities = 246/497 (50%), Positives = 290/497 (59%), Gaps = 59/497 (11%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPT-VCDDDPVMLRPHAE--RGLP-TVSSSDAVQQ 63 G V VAG V+G A VL GA T V D D R A R L TV D Sbjct 8 GTRVTVAGLGVSGMPAARVLHARGALVTAVTDADDERSRAQAGELRALGITVRLGDGSTL 67 Query 64 ITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRS-WLVVTGTN 122 G LVV +PG+ P PL AAA AAGVP+WGDVELAWRL GP + WL VTGTN Sbjct 68 PEGTELVVTAPGWQPGKPLFAAAEAAGVPVWGDVELAWRL-----RGPDAAPWLAVTGTN 122 Query 123 GKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVL--DEPAELLAVELSSFQLHWAPSLRP 180 GKTTT ML A+L A G R GNIG ++LD + +EP ++LAVELSS+QLHWAPS+RP Sbjct 123 GKTTTVRMLAAILEAAGHRTAAVGNIGVSLLDAVLAEEPYDVLAVELSSYQLHWAPSVRP 182 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDS---------RAAALLDGS 231 + AVLN+A DHLDWH +MA Y A K RV G VA + +S RAA + +G Sbjct 183 HSAAVLNLAPDHLDWHGSMAAYAADKGRVYEGN-QVACVYNSADPATEELVRAADVEEGC 241 Query 232 PAQVRVGFRLGEPAARELGVRDAHLVDRAFSDD-----LTLLPVASIPVPGPVGVLDALA 286 A +GF LG P ELGV + +LVDRAF D L VA + P P + +ALA Sbjct 242 RA---IGFTLGTPRPSELGVVEGYLVDRAFVPDRAQQAQELAEVADVDPPAPHNIANALA 298 Query 287 AAALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYP 346 AAALAR+ GVPA A+ + + +FR HR E VA DG+ YVDDSKATN HAA AS+ AY Sbjct 299 AAALARAFGVPATAVREGLRAFRPDPHRIEHVATIDGVAYVDDSKATNTHAAEASLAAYE 358 Query 347 RVVWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGED 406 +VWIAGGL KGAS V A RL VL+GRDRA + EAL+RHAP+VPVV + D Sbjct 359 PIVWIAGGLAKGASFDELVQGAAKRLRAVVLMGRDRALIREALARHAPNVPVVDLDRA-D 417 Query 407 TGMPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQ 466 TG M+ AV A +A+ GDTVLLAPA AS D Sbjct 418 TG----------------------------AMSEAVREAAGLAESGDTVLLAPACASMDM 449 Query 467 FTGYADRGEAFATAVRA 483 FT Y RG+ FA AVRA Sbjct 450 FTNYNVRGDLFAEAVRA 466 >gi|318057552|ref|ZP_07976275.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Streptomyces sp. SA3_actG] gi|318079765|ref|ZP_07987097.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [Streptomyces sp. SA3_actF] Length=474 Score = 340 bits (873), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 245/497 (50%), Positives = 289/497 (59%), Gaps = 59/497 (11%) Query 8 GAPVLVAGGRVTGQAVAAVLTRFGATPT-VCDDDPVMLRPHAE--RGLP-TVSSSDAVQQ 63 G V VAG V+G A VL GA T V D D R A R L TV D Sbjct 8 GTRVTVAGLGVSGMPAARVLHARGALVTAVTDADDERSRAQAGELRALGITVRLGDGSTL 67 Query 64 ITGYALVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRS-WLVVTGTN 122 G LVV +PG+ P PL AAA AAGVP+WGDVELAWRL GP + WL VTGTN Sbjct 68 PEGTELVVTAPGWQPGKPLFAAAEAAGVPVWGDVELAWRL-----RGPDAAPWLAVTGTN 122 Query 123 GKTTTTSMLHAMLIAGGRRAVLCGNIGSAVLDVL--DEPAELLAVELSSFQLHWAPSLRP 180 GKTTT ML A+L A G R GNIG ++LD + +EP ++LAVELSS+QLHWAPS+RP Sbjct 123 GKTTTVRMLSAILEAAGHRTAAVGNIGVSLLDAVLAEEPYDVLAVELSSYQLHWAPSVRP 182 Query 181 EAGAVLNIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDS---------RAAALLDGS 231 + AVLN+A DHLDWH +MA Y A K RV G VA + +S RAA + +G Sbjct 183 HSAAVLNLAPDHLDWHGSMAAYAADKGRVYEGN-QVACVYNSADPATEELVRAADVEEGC 241 Query 232 PAQVRVGFRLGEPAARELGVRDAHLVDRAFSDD-----LTLLPVASIPVPGPVGVLDALA 286 A +GF LG P ELGV + +LVDRAF D L VA + P P + +ALA Sbjct 242 RA---IGFTLGTPRPSELGVVEGYLVDRAFVPDRAQQAQELAEVADVDPPAPHNIANALA 298 Query 287 AAALARSVGVPAGAIADAVTSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYP 346 AAALAR+ GVPA A+ + +FR HR E VA DG+ YVDDSKATN HAA AS+ AY Sbjct 299 AAALARAFGVPATAVRAGLRAFRPDPHRIEHVATIDGVAYVDDSKATNTHAAEASLAAYE 358 Query 347 RVVWIAGGLLKGASLHAEVAAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGED 406 +VWIAGGL KGA+ V A RL VL+GRDRA + EAL+RHAP+VPVV + D Sbjct 359 PIVWIAGGLAKGATFDELVQGAAKRLRAVVLMGRDRALIREALARHAPNVPVVDLDRA-D 417 Query 407 TGMPATVEVPVACVLDVAKDDKAGETVGAAVMTAAVAAARRMAQPGDTVLLAPAGASFDQ 466 TG M+ AV A +A+ GDTVLLAPA AS D Sbjct 418 TG----------------------------AMSEAVREAAGLAESGDTVLLAPACASMDM 449 Query 467 FTGYADRGEAFATAVRA 483 FT Y RG+ FA AVRA Sbjct 450 FTNYNVRGDLFAEAVRA 466 >gi|262202912|ref|YP_003274120.1| UDP-N-acetylmuramoylalanine/D-glutamate ligase [Gordonia bronchialis DSM 43247] gi|262086259|gb|ACY22227.1| UDP-N-acetylmuramoylalanine/D-glutamate ligase [Gordonia bronchialis DSM 43247] Length=512 Score = 340 bits (872), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 224/417 (54%), Positives = 273/417 (66%), Gaps = 23/417 (5%) Query 69 LVVASPGFSPATPLLAAAAAAGVPIWGDVELAWRLDAAGCYGPPRSWLVVTGTNGKTTTT 128 LVV SPGF+P P+ AAA VP+WG+VELAWR+D AG GPPR+WLVVTGTNGKTTTT Sbjct 82 LVVVSPGFAPTHPVAVAAADGSVPVWGEVELAWRVDRAGILGPPRTWLVVTGTNGKTTTT 141 Query 129 SMLHAMLIAGGRRAVLCGNIGSAVLD--VLDEPAELLAVELSSFQLHWAPSLRPEAGAVL 186 SML +++AGGR + CGNIG VLD ++ ++L ELSSFQLHWAPS+RP+AG VL Sbjct 142 SMLADIVVAGGRSGIACGNIGLPVLDAMLMAPRVDVLCAELSSFQLHWAPSVRPDAGVVL 201 Query 187 NIAEDHLDWHATMAEYTAAKARVLTGGVAVAGLDDSRAAALLDGSPAQ-VRVGFRLGEPA 245 N+AEDHLDWH Y AK R LTG V+V GLDD A L P Q RVGF LGEP Sbjct 202 NVAEDHLDWHGGFDGYAGAKTRALTGAVSVVGLDDEVAGGL----PTQGRRVGFTLGEPG 257 Query 246 ARELGVRDAHLVDRAFSDDLTLLPVASIPVPGPVGVLDALAAAALARSVGVPAGAIADAV 305 +LGV A LVDRAF + LL +I PGP G+ DALAA+ALA + GV A+ADA+ Sbjct 258 PDDLGVVGAELVDRAFGSGV-LLAAEAIHPPGPSGLSDALAASALALAAGVDRAAVADAL 316 Query 306 TSFRVGRHRAEVVAVADGITYVDDSKATNPHAARASVLAYPRVVWIAGGLLKGASLHAEV 365 T+FR HR EVVA + GI +VDDSKATNPHAA+A++ + RVV IAGGLLKGAS+ + Sbjct 317 TAFRPAGHRGEVVAESAGIRFVDDSKATNPHAAQAAIAGFDRVVLIAGGLLKGASVDRMI 376 Query 366 AAMASRLVGAVLIGRDRAAVAEALSRHAPDVPVVQVVAGEDTGMPATVEVPVACVLDVAK 425 A+ RL G V IG+DR + +A++RHAP+VP V V G+D G+ +AC ++A Sbjct 377 DAVRHRLAGVVAIGQDRDIIVDAIARHAPEVPTVTVFTGDDGGVNVH---RMACARNLAS 433 Query 426 DDKAGETVG--------AAVMTAAVAAARRMAQPGD----TVLLAPAGASFDQFTGY 470 + V AVM AV A +A D VLLAPA AS D F GY Sbjct 434 ARNHADPVSPGSPTDPAVAVMDRAVVEAWHLAGAADPTPQAVLLAPAAASLDMFAGY 490 Lambda K H 0.319 0.133 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1035168197832 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40