BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2157c Length=510 Score E Sequences producing significant alignments: (Bits) Value gi|15609294|ref|NP_216673.1| UDP-N-acetylmuramoylalanyl-D-glutam... 988 0.0 gi|253798778|ref|YP_003031779.1| UDP-N-acetylmuramoylalanyl-D-gl... 987 0.0 gi|340627165|ref|YP_004745617.1| putative UDP-N-acetylmuramoylal... 985 0.0 gi|15841649|ref|NP_336686.1| UDP-N-acetylmuramoylalanyl-D-glutam... 983 0.0 gi|289745432|ref|ZP_06504810.1| UDP-N-acetylmuramoylalanyl-D-glu... 883 0.0 gi|167966741|ref|ZP_02549018.1| UDP-N-acetylmuramoylalanyl-D-glu... 863 0.0 gi|298525651|ref|ZP_07013060.1| UDP-N-acetylmuramoylalanyl-D-glu... 853 0.0 gi|306784930|ref|ZP_07423252.1| UDP-N-acetylmuramoylalanyl-D-glu... 848 0.0 gi|306968291|ref|ZP_07480952.1| putative Mur ligase family, glut... 843 0.0 gi|306793625|ref|ZP_07431927.1| putative Mur ligase family, glut... 839 0.0 gi|289754267|ref|ZP_06513645.1| UDP-N-acetylmuramoylalanyl-D-glu... 768 0.0 gi|289750754|ref|ZP_06510132.1| UDP-N-acetylmuramoylalanyl-D-glu... 764 0.0 gi|307084810|ref|ZP_07493923.1| putative Mur ligase family, glut... 761 0.0 gi|240168221|ref|ZP_04746880.1| UDP-N-acetylmuramoylalanyl-D-glu... 741 0.0 gi|289758277|ref|ZP_06517655.1| UDP-N-acetylmuramoylalanyl-D-glu... 718 0.0 gi|254775004|ref|ZP_05216520.1| hypothetical protein MaviaA2_100... 709 0.0 gi|118467198|ref|YP_881536.1| UDP-N-acetylmuramoyl-tripeptide--D... 709 0.0 gi|41407999|ref|NP_960835.1| hypothetical protein MAP1901c [Myco... 709 0.0 gi|183983187|ref|YP_001851478.1| UDP-N-acetylmuramoylalanyl-D-gl... 708 0.0 gi|336461947|gb|EGO40799.1| UDP-N-acetylmuramoyl-tripeptide--D-a... 706 0.0 gi|118618799|ref|YP_907131.1| UDP-N-acetylmuramoylalanyl-D-gluta... 685 0.0 gi|342859873|ref|ZP_08716526.1| UDP-N-acetylmuramoyl-tripeptide-... 681 0.0 gi|15827430|ref|NP_301693.1| UDP-N-acetylmuramoylalanyl-D-glutam... 669 0.0 gi|120404499|ref|YP_954328.1| UDP-N-acetylmuramoylalanyl-D-gluta... 664 0.0 gi|118473094|ref|YP_888508.1| UDP-N-acetylmuramoyl-tripeptide--D... 659 0.0 gi|254232315|ref|ZP_04925642.1| UDP-N-acetylmuramoylalanyl-D-glu... 634 2e-179 gi|145223571|ref|YP_001134249.1| UDP-N-acetylmuramoylalanyl-D-gl... 611 9e-173 gi|333990379|ref|YP_004522993.1| UDP-N-acetylmuramoylalanyl-D-gl... 611 1e-172 gi|108800226|ref|YP_640423.1| UDP-N-acetylmuramoyl-tripeptide--D... 609 3e-172 gi|315443918|ref|YP_004076797.1| UDP-N-acetylmuramoyl-tripeptide... 605 8e-171 gi|289447785|ref|ZP_06437529.1| phospho-N-acetylMuramoyl-pentape... 587 2e-165 gi|254821976|ref|ZP_05226977.1| hypothetical protein MintA_18732... 586 3e-165 gi|296166025|ref|ZP_06848476.1| UDP-N-acetylmuramoyl-tripeptide-... 577 2e-162 gi|339295073|gb|AEJ47184.1| UDP-N-acetylmuramoylalanyl-D-glutamy... 575 1e-161 gi|312140146|ref|YP_004007482.1| UDP-N-acetylmuramoyl-tripeptide... 534 2e-149 gi|325676973|ref|ZP_08156645.1| UDP-N-acetylmuramoyl-tripeptide-... 531 8e-149 gi|169629089|ref|YP_001702738.1| UDP-N-acetylmuramoyl-tripeptide... 531 9e-149 gi|111018105|ref|YP_701077.1| UDP-N-acetylmuramoyl-tripeptide--D... 524 2e-146 gi|226360234|ref|YP_002778012.1| UDP-N-acetylmuramoyl-tripeptide... 519 6e-145 gi|289443662|ref|ZP_06433406.1| hypothetical protein TBLG_00764 ... 505 8e-141 gi|54023730|ref|YP_117972.1| putative UDP-N-acetylmuramoylalanyl... 504 2e-140 gi|256379769|ref|YP_003103429.1| UDP-N-acetylmuramoylalanyl-D-gl... 501 9e-140 gi|333918994|ref|YP_004492575.1| UDP-N-acetylmuramoyl-tripeptide... 497 2e-138 gi|296140346|ref|YP_003647589.1| UDP-N-acetylmuramoylalanyl-D-gl... 497 2e-138 gi|226307043|ref|YP_002767003.1| UDP-N-acetylmuramoyl-tripeptide... 487 2e-135 gi|229490386|ref|ZP_04384227.1| UDP-N-acetylmuramoyl-tripeptide-... 486 4e-135 gi|300788101|ref|YP_003768392.1| UDP-N-acetylmuramoylalanyl-D-gl... 471 1e-130 gi|302528473|ref|ZP_07280815.1| UDP-N-acetylmuramoyl-tripeptide-... 470 2e-130 gi|319949798|ref|ZP_08023821.1| UDP-N-acetylmuramoyl-tripeptide-... 470 3e-130 gi|257056721|ref|YP_003134553.1| UDP-N-acetylmuramoyl-tripeptide... 461 1e-127 >gi|15609294|ref|NP_216673.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis H37Rv] gi|31793337|ref|NP_855830.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamino pimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium bovis AF2122/97] gi|121638039|ref|YP_978263.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium bovis BCG str. Pasteur 1173P2] 27 more sequence titles Length=510 Score = 988 bits (2554), Expect = 0.0, Method: Compositional matrix adjust. Identities = 510/510 (100%), Positives = 510/510 (100%), Gaps = 0/510 (0%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH Sbjct 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV Sbjct 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR Sbjct 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH Sbjct 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE 300 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE Sbjct 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE 300 Query 301 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD 360 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD Sbjct 301 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD 360 Query 361 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS 420 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS Sbjct 361 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS 420 Query 421 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD 480 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD Sbjct 421 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD 480 Query 481 VVLVKASNAAGLGAVADALVADDTCGSVRP 510 VVLVKASNAAGLGAVADALVADDTCGSVRP Sbjct 481 VVLVKASNAAGLGAVADALVADDTCGSVRP 510 >gi|253798778|ref|YP_003031779.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis KZN 1435] gi|289554056|ref|ZP_06443266.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis KZN 605] gi|297634746|ref|ZP_06952526.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium tuberculosis KZN 4207] gi|297731735|ref|ZP_06960853.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium tuberculosis KZN R506] gi|313659070|ref|ZP_07815950.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium tuberculosis KZN V2475] gi|253320281|gb|ACT24884.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis KZN 1435] gi|289438688|gb|EFD21181.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis KZN 605] gi|328458541|gb|AEB03964.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis KZN 4207] Length=510 Score = 987 bits (2552), Expect = 0.0, Method: Compositional matrix adjust. Identities = 509/510 (99%), Positives = 509/510 (99%), Gaps = 0/510 (0%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH Sbjct 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV Sbjct 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR Sbjct 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH Sbjct 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE 300 SGAVVLNADDPAVAAMAKLTAARV RVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE Sbjct 241 SGAVVLNADDPAVAAMAKLTAARVARVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE 300 Query 301 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD 360 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD Sbjct 301 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD 360 Query 361 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS 420 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS Sbjct 361 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS 420 Query 421 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD 480 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD Sbjct 421 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD 480 Query 481 VVLVKASNAAGLGAVADALVADDTCGSVRP 510 VVLVKASNAAGLGAVADALVADDTCGSVRP Sbjct 481 VVLVKASNAAGLGAVADALVADDTCGSVRP 510 >gi|340627165|ref|YP_004745617.1| putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium canettii CIPT 140010059] gi|340005355|emb|CCC44513.1| putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium canettii CIPT 140010059] Length=510 Score = 985 bits (2547), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/510 (99%), Positives = 509/510 (99%), Gaps = 0/510 (0%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH Sbjct 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV Sbjct 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR Sbjct 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH Sbjct 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE 300 SGAVVLN DDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDE+ARPRFTLHAHDAQAE Sbjct 241 SGAVVLNVDDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDEVARPRFTLHAHDAQAE 300 Query 301 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD 360 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD Sbjct 301 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD 360 Query 361 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS 420 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS Sbjct 361 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS 420 Query 421 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD 480 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD Sbjct 421 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD 480 Query 481 VVLVKASNAAGLGAVADALVADDTCGSVRP 510 VVLVKASNAAGLGAVADALVADDTCGSVRP Sbjct 481 VVLVKASNAAGLGAVADALVADDTCGSVRP 510 >gi|15841649|ref|NP_336686.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase [Mycobacterium tuberculosis CDC1551] gi|13881901|gb|AAK46500.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase [Mycobacterium tuberculosis CDC1551] Length=510 Score = 983 bits (2540), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/510 (99%), Positives = 508/510 (99%), Gaps = 0/510 (0%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFL LPGARADGHDH Sbjct 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLRLPGARADGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV Sbjct 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR Sbjct 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH Sbjct 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE 300 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE Sbjct 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE 300 Query 301 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD 360 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD Sbjct 301 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD 360 Query 361 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS 420 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS Sbjct 361 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS 420 Query 421 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD 480 RLVVVGTGRSISAMHHGAVLE AWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD Sbjct 421 RLVVVGTGRSISAMHHGAVLEEAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD 480 Query 481 VVLVKASNAAGLGAVADALVADDTCGSVRP 510 VVLVKASNAAGLGAVADALVADDTCGSVRP Sbjct 481 VVLVKASNAAGLGAVADALVADDTCGSVRP 510 >gi|289745432|ref|ZP_06504810.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis 02_1987] gi|289685960|gb|EFD53448.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis 02_1987] Length=463 Score = 883 bits (2282), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/463 (99%), Positives = 457/463 (99%), Gaps = 0/463 (0%) Query 48 LALPGARADGHDHAASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGA 107 +A P RAD DH ASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGA Sbjct 1 MAFPRQRADSKDHVASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGA 60 Query 108 AVLAALAKLATAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNE 167 AVLAALAKLATAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNE Sbjct 61 AVLAALAKLATAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNE 120 Query 168 LGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVI 227 LGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVI Sbjct 121 LGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVI 180 Query 228 AQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELAR 287 AQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELAR Sbjct 181 AQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELAR 240 Query 288 PRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQ 347 PRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQ Sbjct 241 PRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQ 300 Query 348 VTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEH 407 VTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEH Sbjct 301 VTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEH 360 Query 408 DRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDA 467 DRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDA Sbjct 361 DRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDA 420 Query 468 ALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVRP 510 ALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVRP Sbjct 421 ALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVRP 463 >gi|167966741|ref|ZP_02549018.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase murF [Mycobacterium tuberculosis H37Ra] Length=445 Score = 863 bits (2229), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/445 (100%), Positives = 445/445 (100%), Gaps = 0/445 (0%) Query 66 AAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLV 125 AAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLV Sbjct 1 AAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLV 60 Query 126 AGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLI 185 AGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLI Sbjct 61 AGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLI 120 Query 186 LEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVV 245 LEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVV Sbjct 121 LEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVV 180 Query 246 LNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGV 305 LNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGV Sbjct 181 LNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGV 240 Query 306 CGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNAN 365 CGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNAN Sbjct 241 CGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNAN 300 Query 366 PDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVV 425 PDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVV Sbjct 301 PDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVV 360 Query 426 GTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVK 485 GTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVK Sbjct 361 GTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVK 420 Query 486 ASNAAGLGAVADALVADDTCGSVRP 510 ASNAAGLGAVADALVADDTCGSVRP Sbjct 421 ASNAAGLGAVADALVADDTCGSVRP 445 >gi|298525651|ref|ZP_07013060.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase [Mycobacterium tuberculosis 94_M4241A] gi|308376925|ref|ZP_07668381.1| putative Mur ligase family, glutamate ligase domain protein [Mycobacterium tuberculosis SUMu008] gi|298495445|gb|EFI30739.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase [Mycobacterium tuberculosis 94_M4241A] gi|308349502|gb|EFP38353.1| putative Mur ligase family, glutamate ligase domain protein [Mycobacterium tuberculosis SUMu008] Length=439 Score = 853 bits (2204), Expect = 0.0, Method: Compositional matrix adjust. Identities = 438/439 (99%), Positives = 439/439 (100%), Gaps = 0/439 (0%) Query 72 VLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTI 131 +LAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTI Sbjct 1 MLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTI 60 Query 132 IGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAAR 191 IGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAAR Sbjct 61 IGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAAR 120 Query 192 HHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDP 251 HHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDP Sbjct 121 HHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDP 180 Query 252 AVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQV 311 AVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQV Sbjct 181 AVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQV 240 Query 312 TNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRA 371 TNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRA Sbjct 241 TNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRA 300 Query 372 GLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSI 431 GLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSI Sbjct 301 GLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSI 360 Query 432 SAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAG 491 SAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAG Sbjct 361 SAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAG 420 Query 492 LGAVADALVADDTCGSVRP 510 LGAVADALVADDTCGSVRP Sbjct 421 LGAVADALVADDTCGSVRP 439 >gi|306784930|ref|ZP_07423252.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis SUMu003] gi|308330389|gb|EFP19240.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis SUMu003] Length=435 Score = 848 bits (2191), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/435 (100%), Positives = 435/435 (100%), Gaps = 0/435 (0%) Query 76 RPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGIT 135 RPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGIT Sbjct 1 RPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGIT 60 Query 136 GSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGN 195 GSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGN Sbjct 61 GSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGN 120 Query 196 IAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAA 255 IAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAA Sbjct 121 IAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAA 180 Query 256 MAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNAL 315 MAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNAL Sbjct 181 MAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNAL 240 Query 316 CAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQA 375 CAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQA Sbjct 241 CAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQA 300 Query 376 LAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMH 435 LAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMH Sbjct 301 LAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMH 360 Query 436 HGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAV 495 HGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAV Sbjct 361 HGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAV 420 Query 496 ADALVADDTCGSVRP 510 ADALVADDTCGSVRP Sbjct 421 ADALVADDTCGSVRP 435 >gi|306968291|ref|ZP_07480952.1| putative Mur ligase family, glutamate ligase domain protein [Mycobacterium tuberculosis SUMu009] gi|308354132|gb|EFP42983.1| putative Mur ligase family, glutamate ligase domain protein [Mycobacterium tuberculosis SUMu009] Length=432 Score = 843 bits (2177), Expect = 0.0, Method: Compositional matrix adjust. Identities = 432/432 (100%), Positives = 432/432 (100%), Gaps = 0/432 (0%) Query 79 GVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGITGSS 138 GVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGITGSS Sbjct 1 GVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGITGSS 60 Query 139 GKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAA 198 GKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAA Sbjct 61 GKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAA 120 Query 199 LAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAK 258 LAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAK Sbjct 121 LAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAK 180 Query 259 LTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAA 318 LTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAA Sbjct 181 LTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAA 240 Query 319 AVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAW 378 AVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAW Sbjct 241 AVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAW 300 Query 379 IAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGA 438 IAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGA Sbjct 301 IAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGA 360 Query 439 VLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADA 498 VLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADA Sbjct 361 VLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADA 420 Query 499 LVADDTCGSVRP 510 LVADDTCGSVRP Sbjct 421 LVADDTCGSVRP 432 >gi|306793625|ref|ZP_07431927.1| putative Mur ligase family, glutamate ligase domain protein [Mycobacterium tuberculosis SUMu005] gi|308372153|ref|ZP_07427619.2| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis SUMu004] gi|308334223|gb|EFP23074.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis SUMu004] gi|308338019|gb|EFP26870.1| putative Mur ligase family, glutamate ligase domain protein [Mycobacterium tuberculosis SUMu005] gi|323719312|gb|EGB28454.1| UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase [Mycobacterium tuberculosis CDC1551A] Length=431 Score = 839 bits (2168), Expect = 0.0, Method: Compositional matrix adjust. Identities = 430/431 (99%), Positives = 431/431 (100%), Gaps = 0/431 (0%) Query 80 VPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGITGSSG 139 +PAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGITGSSG Sbjct 1 MPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGITGSSG 60 Query 140 KTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAAL 199 KTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAAL Sbjct 61 KTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAAL 120 Query 200 AEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKL 259 AEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKL Sbjct 121 AEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKL 180 Query 260 TAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAA 319 TAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAA Sbjct 181 TAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAA 240 Query 320 VALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWI 379 VALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWI Sbjct 241 VALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWI 300 Query 380 AHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAV 439 AHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAV Sbjct 301 AHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAV 360 Query 440 LEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADAL 499 LEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADAL Sbjct 361 LEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADAL 420 Query 500 VADDTCGSVRP 510 VADDTCGSVRP Sbjct 421 VADDTCGSVRP 431 >gi|289754267|ref|ZP_06513645.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis EAS054] gi|308369637|ref|ZP_07666768.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis SUMu002] gi|289694854|gb|EFD62283.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis EAS054] gi|308326954|gb|EFP15805.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis SUMu002] Length=391 Score = 768 bits (1982), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/391 (99%), Positives = 391/391 (100%), Gaps = 0/391 (0%) Query 120 VAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATR 179 +AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATR Sbjct 1 MAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATR 60 Query 180 RTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVP 239 RTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVP Sbjct 61 RTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVP 120 Query 240 HSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQA 299 HSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQA Sbjct 121 HSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQA 180 Query 300 EVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVID 359 EVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVID Sbjct 181 EVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVID 240 Query 360 DAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDV 419 DAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDV Sbjct 241 DAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDV 300 Query 420 SRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPG 479 SRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPG Sbjct 301 SRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPG 360 Query 480 DVVLVKASNAAGLGAVADALVADDTCGSVRP 510 DVVLVKASNAAGLGAVADALVADDTCGSVRP Sbjct 361 DVVLVKASNAAGLGAVADALVADDTCGSVRP 391 >gi|289750754|ref|ZP_06510132.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase [Mycobacterium tuberculosis T92] gi|289691341|gb|EFD58770.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase [Mycobacterium tuberculosis T92] Length=391 Score = 764 bits (1974), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/391 (99%), Positives = 390/391 (99%), Gaps = 0/391 (0%) Query 120 VAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATR 179 +AAQ VAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATR Sbjct 1 MAAQWVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATR 60 Query 180 RTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVP 239 RTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVP Sbjct 61 RTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVP 120 Query 240 HSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQA 299 HSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQA Sbjct 121 HSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQA 180 Query 300 EVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVID 359 EVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVID Sbjct 181 EVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVID 240 Query 360 DAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDV 419 DAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDV Sbjct 241 DAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDV 300 Query 420 SRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPG 479 SRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPG Sbjct 301 SRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPG 360 Query 480 DVVLVKASNAAGLGAVADALVADDTCGSVRP 510 DVVLVKASNAAGLGAVADALVADDTCGSVRP Sbjct 361 DVVLVKASNAAGLGAVADALVADDTCGSVRP 391 >gi|307084810|ref|ZP_07493923.1| putative Mur ligase family, glutamate ligase domain protein [Mycobacterium tuberculosis SUMu012] gi|308365624|gb|EFP54475.1| putative Mur ligase family, glutamate ligase domain protein [Mycobacterium tuberculosis SUMu012] Length=392 Score = 761 bits (1966), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/387 (100%), Positives = 387/387 (100%), Gaps = 0/387 (0%) Query 124 LVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDY 183 LVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDY Sbjct 6 LVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDY 65 Query 184 LILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGA 243 LILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGA Sbjct 66 LILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGA 125 Query 244 VVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRL 303 VVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRL Sbjct 126 VVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRL 185 Query 304 GVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYN 363 GVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYN Sbjct 186 GVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYN 245 Query 364 ANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLV 423 ANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLV Sbjct 246 ANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLV 305 Query 424 VVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVL 483 VVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVL Sbjct 306 VVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVL 365 Query 484 VKASNAAGLGAVADALVADDTCGSVRP 510 VKASNAAGLGAVADALVADDTCGSVRP Sbjct 366 VKASNAAGLGAVADALVADDTCGSVRP 392 >gi|240168221|ref|ZP_04746880.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase [Mycobacterium kansasii ATCC 12478] Length=524 Score = 741 bits (1912), Expect = 0.0, Method: Compositional matrix adjust. Identities = 420/510 (83%), Positives = 450/510 (89%), Gaps = 13/510 (2%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI+LTVAQIA+IVGG +ADISPQDAA RRVTGTVEFDSRAIGPGGLFLALPGA DGHD+ Sbjct 1 MIDLTVAQIADIVGGTLADISPQDAAQRRVTGTVEFDSRAIGPGGLFLALPGAHVDGHDY 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPP--VAAPNVLAGVLEHDNDGSGAAVLAALAKLAT 118 AASA AAGA VLAARPVGVPAIVV P A LAGVLEHD DGSGAAVLAALAKLA Sbjct 61 AASAAAAGAVAVLAARPVGVPAIVVTPERSLAEGALAGVLEHDADGSGAAVLAALAKLAK 120 Query 119 AVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRAT 178 AVAA+LVAGGLTIIGITGSSGKTSTKDL+AAVL PLG VVAPPGSFNNELGHPWTVLRA Sbjct 121 AVAAELVAGGLTIIGITGSSGKTSTKDLVAAVLQPLGVVVAPPGSFNNELGHPWTVLRAG 180 Query 179 RRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAV 238 R TDYLILEM+ARH GNIAALA+IA P+IGVVLNVGTAHLGEFGSRE IA+TK+ELPQAV Sbjct 181 RDTDYLILEMSARHPGNIAALAQIATPAIGVVLNVGTAHLGEFGSREAIARTKSELPQAV 240 Query 239 PHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQ 298 P SG V+LNADDPAVAAMA++TAARVVRVSR +TGDVWAGPVSLDELARP+FT+HA Q Sbjct 241 PQSGVVILNADDPAVAAMAEVTAARVVRVSRGSTGDVWAGPVSLDELARPQFTVHAGATQ 300 Query 299 AEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVI 358 AEVRLGV GDHQV+NALCAAAVALECGA+++QVA AL A PVSRHRMQVTTR DGVTVI Sbjct 301 AEVRLGVYGDHQVSNALCAAAVALECGATLDQVATALGGAGPVSRHRMQVTTRADGVTVI 360 Query 359 DDAYNANPDSMRAGLQALAWIAHQPE-------ATRRSWAVLGEMAELGEDAIAEHDRIG 411 DDAYNANPDSM AGLQALAWIA A RRSWAVLGEMAELG DAIAEHDR+G Sbjct 361 DDAYNANPDSMGAGLQALAWIARGGSGAGSDLAAKRRSWAVLGEMAELGADAIAEHDRVG 420 Query 412 RLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALAL 471 RLAVRLDVSRLVVVGTGRS+SAMHHGAVLEGAWGS A GADR VNVAD DAAL L Sbjct 421 RLAVRLDVSRLVVVGTGRSVSAMHHGAVLEGAWGSWGA----GADRGTVNVADADAALEL 476 Query 472 LRAELRPGDVVLVKASNAAGLGAVADALVA 501 LRAE++PGDV+L+KASN+AGLGA+ADALV+ Sbjct 477 LRAEVQPGDVILIKASNSAGLGALADALVS 506 >gi|289758277|ref|ZP_06517655.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis T85] gi|289713841|gb|EFD77853.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis T85] Length=364 Score = 718 bits (1853), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/364 (100%), Positives = 364/364 (100%), Gaps = 0/364 (0%) Query 147 MAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPPS 206 MAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPPS Sbjct 1 MAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPPS 60 Query 207 IGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVR 266 IGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVR Sbjct 61 IGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVR 120 Query 267 VSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGA 326 VSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGA Sbjct 121 VSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGA 180 Query 327 SVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEAT 386 SVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEAT Sbjct 181 SVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEAT 240 Query 387 RRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGS 446 RRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGS Sbjct 241 RRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGS 300 Query 447 GEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCG 506 GEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCG Sbjct 301 GEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCG 360 Query 507 SVRP 510 SVRP Sbjct 361 SVRP 364 >gi|254775004|ref|ZP_05216520.1| hypothetical protein MaviaA2_10069 [Mycobacterium avium subsp. avium ATCC 25291] Length=519 Score = 709 bits (1830), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/501 (82%), Positives = 439/501 (88%), Gaps = 21/501 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI+LTVAQIA+IVGG +ADI+ DAA RRVTGTVEFDSRA+GPGGLFLALPGAR DGHDH Sbjct 1 MIDLTVAQIADIVGGTLADITAPDAARRRVTGTVEFDSRAVGPGGLFLALPGARTDGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 A SAVAAGA VLAARPVGVPAIV PPV A + LAGVLEHD DGSGAAVLAALAKLA AV Sbjct 61 AESAVAAGAVAVLAARPVGVPAIVAPPVDAADALAGVLEHDADGSGAAVLAALAKLARAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AA+LVAGGLTI+GITGSSGKTSTKDL+AAVLAPLGEVVAPPGSFNNELGHPWTVLRAT Sbjct 121 AAELVAGGLTIVGITGSSGKTSTKDLVAAVLAPLGEVVAPPGSFNNELGHPWTVLRATAD 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TDYL+LEM+ARH GNIAALAEIAPP++GVVLNVGTAHLGEFGSRE IA+TK+ELPQAVP Sbjct 181 TDYLVLEMSARHPGNIAALAEIAPPAVGVVLNVGTAHLGEFGSREAIARTKSELPQAVPA 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSR-DNT----GDVWAGPVSLDELARPRFTLHAH 295 SG VVLN DDP VAAMA++TAARVVRVSR ++T DVWAGPVSLDELARP FTL+ Sbjct 241 SGVVVLNVDDPTVAAMAEVTAARVVRVSRAEHTEAGPSDVWAGPVSLDELARPGFTLYHR 300 Query 296 DA----QAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTR 351 A QA V+LGV GDHQV NALCAAAVALECGA+VEQV AAL A PVSRHRMQV+TR Sbjct 301 HAGGTRQARVQLGVSGDHQVGNALCAAAVALECGATVEQVVAALAGAGPVSRHRMQVSTR 360 Query 352 GDGVTVIDDAYNANPDSMRAGLQALAWIAH---QPEA-TRRSWAVLGEMAELGEDAIAEH 407 GDGVTVIDDAYNANPDSMRAGLQALAWIA +P A RRSWAVLGEMAELG+DAIAEH Sbjct 361 GDGVTVIDDAYNANPDSMRAGLQALAWIARGGAEPGAPARRSWAVLGEMAELGDDAIAEH 420 Query 408 DRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDA 467 DRIGRLAVRLDVSRLVVVGTGRS+SAMHHGAV+EG+WGS AD+ AVNV D +A Sbjct 421 DRIGRLAVRLDVSRLVVVGTGRSVSAMHHGAVMEGSWGS--------ADKGAVNVPDAEA 472 Query 468 ALALLRAELRPGDVVLVKASN 488 AL LLRAEL+PGDVVLVKASN Sbjct 473 ALELLRAELQPGDVVLVKASN 493 >gi|118467198|ref|YP_881536.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium avium 104] gi|118168485|gb|ABK69382.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium avium 104] Length=533 Score = 709 bits (1829), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/501 (82%), Positives = 440/501 (88%), Gaps = 21/501 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI+LTVAQIA+IVGG +ADI+ DAA RRVTGTVEFDSRA+GPGGLFLALPGAR DGHDH Sbjct 1 MIDLTVAQIADIVGGTLADITAPDAARRRVTGTVEFDSRAVGPGGLFLALPGARTDGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 A SAVAAGA VLAARPVGVPAIV PPV A + LAGVLEHD DGSGAAVLAALAKLA AV Sbjct 61 AESAVAAGAVAVLAARPVGVPAIVAPPVDAADALAGVLEHDADGSGAAVLAALAKLARAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AA+LVAGGLTI+GITGSSGKTSTKDL+AAVLAPLGEVVAPPGSFNNELGHPWTVLRAT Sbjct 121 AAELVAGGLTIVGITGSSGKTSTKDLVAAVLAPLGEVVAPPGSFNNELGHPWTVLRATAD 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TDYL+LEM+ARH GNIAALAEIAPP++GVVLNVGTAHLGEFGSRE IA+TK+ELPQ+VP Sbjct 181 TDYLVLEMSARHPGNIAALAEIAPPAVGVVLNVGTAHLGEFGSREAIARTKSELPQSVPA 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSR-DNT----GDVWAGPVSLDELARPRFTL-HA 294 SG VVLN DDP VAAMA++TAARVVRVSR ++T DVWAGPVSLDELARP FTL H+ Sbjct 241 SGVVVLNVDDPTVAAMAEVTAARVVRVSRAEHTEAGPSDVWAGPVSLDELARPGFTLYHS 300 Query 295 H---DAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTR 351 H QA V+LGV GDHQV NALCAAAVALECGA+VEQV AAL A PVSRHRMQV+TR Sbjct 301 HAGGTRQARVQLGVSGDHQVGNALCAAAVALECGATVEQVVAALAGAGPVSRHRMQVSTR 360 Query 352 GDGVTVIDDAYNANPDSMRAGLQALAWIAH---QPEA-TRRSWAVLGEMAELGEDAIAEH 407 GDGVTVIDDAYNANPDSMRAGLQALAWIA +P A RRSWAVLGEMAELG+DAIAEH Sbjct 361 GDGVTVIDDAYNANPDSMRAGLQALAWIARGGAEPGAPARRSWAVLGEMAELGDDAIAEH 420 Query 408 DRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDA 467 DRIGRLAVRLDVSRLVVVGTGRS+SAMHHGAV+EG+WGS AD+ AVNV D +A Sbjct 421 DRIGRLAVRLDVSRLVVVGTGRSVSAMHHGAVMEGSWGS--------ADKGAVNVPDAEA 472 Query 468 ALALLRAELRPGDVVLVKASN 488 AL LLRAEL+PGDVVLVKASN Sbjct 473 ALELLRAELQPGDVVLVKASN 493 >gi|41407999|ref|NP_960835.1| hypothetical protein MAP1901c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396353|gb|AAS04218.1| MurF [Mycobacterium avium subsp. paratuberculosis K-10] Length=519 Score = 709 bits (1829), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/501 (82%), Positives = 438/501 (88%), Gaps = 21/501 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MIELTVAQIA+IVGG +ADI+ DAA RRVTGTVEFDSRA+GPGGLFLALPGAR DGHDH Sbjct 1 MIELTVAQIADIVGGTLADITAPDAARRRVTGTVEFDSRAVGPGGLFLALPGARTDGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 A +AVAAGA VLAARPVGVPAIV PPV A + LAGVLEHD DGSGAAVLAALAKLA AV Sbjct 61 AEAAVAAGAVAVLAARPVGVPAIVAPPVDAADALAGVLEHDADGSGAAVLAALAKLARAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AA+LVAGGLTI+GITGSSGKTSTKDL+AAVLAPLGEVVAPPGSFNNELGHPWTVLRAT Sbjct 121 AAELVAGGLTIVGITGSSGKTSTKDLVAAVLAPLGEVVAPPGSFNNELGHPWTVLRATAD 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TDYL+LEM+ARH GNIAALAEIAPP++GVVLNVGTAHLGEFGSRE IA+TK+ELPQAVP Sbjct 181 TDYLVLEMSARHPGNIAALAEIAPPAVGVVLNVGTAHLGEFGSREAIARTKSELPQAVPA 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSR-DNT----GDVWAGPVSLDELARPRFTLHAH 295 SG VVLN DDP VAAMA++TAARVVRV R ++T DVWAGPVSLDELARP FTL+ Sbjct 241 SGVVVLNVDDPTVAAMAEVTAARVVRVGRAEHTEAGPSDVWAGPVSLDELARPGFTLYHR 300 Query 296 DA----QAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTR 351 A QA V+LGV GDHQV NALCAAAVALECGA+VEQV AAL A PVSRHRMQV+TR Sbjct 301 HAGGTRQARVQLGVSGDHQVGNALCAAAVALECGATVEQVVAALAGAGPVSRHRMQVSTR 360 Query 352 GDGVTVIDDAYNANPDSMRAGLQALAWIAH---QPEA-TRRSWAVLGEMAELGEDAIAEH 407 GDGVTVIDDAYNANPDSMRAGLQALAWIA +P A RRSWAVLGEMAELG+DAIAEH Sbjct 361 GDGVTVIDDAYNANPDSMRAGLQALAWIARGGAEPGAPARRSWAVLGEMAELGDDAIAEH 420 Query 408 DRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDA 467 DRIGRLAVRLDVSRLVVVGTGRS+SAMHHGAV+EG+WGS AD+ AVNV D +A Sbjct 421 DRIGRLAVRLDVSRLVVVGTGRSVSAMHHGAVMEGSWGS--------ADKGAVNVPDAEA 472 Query 468 ALALLRAELRPGDVVLVKASN 488 AL LLRAEL+PGDVVLVKASN Sbjct 473 ALELLRAELQPGDVVLVKASN 493 >gi|183983187|ref|YP_001851478.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium marinum M] gi|183176513|gb|ACC41623.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium marinum M] Length=525 Score = 708 bits (1828), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/517 (79%), Positives = 439/517 (85%), Gaps = 37/517 (7%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI+ TVA+IAEIVGG + DISPQ+A RRVTGTVEFDSRA+GPGGLFLALPGARADGHDH Sbjct 1 MIDYTVAEIAEIVGGTLVDISPQEAEQRRVTGTVEFDSRAVGPGGLFLALPGARADGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNV----LAGVLEHDNDGSGAAVLAALAKL 116 AASAVAAGA VLAARPVGVPAIVV P P+V L GVLEHD DGSGAAVLAALAKL Sbjct 61 AASAVAAGAVAVLAARPVGVPAIVVSP--EPDVTADALTGVLEHDADGSGAAVLAALAKL 118 Query 117 ATAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLR 176 A AVAA+LVAGGLTIIGITGSSGKTSTKDL+AAVL PLGEVVAPPGSFNNELGHPWTVLR Sbjct 119 AKAVAAELVAGGLTIIGITGSSGKTSTKDLVAAVLKPLGEVVAPPGSFNNELGHPWTVLR 178 Query 177 ATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQ 236 ATR TDYLILEM+ARH GNIAALA +APP+IGVVLNVGTAHLGEFGSRE+IAQTK+ELPQ Sbjct 179 ATRGTDYLILEMSARHPGNIAALARVAPPAIGVVLNVGTAHLGEFGSREIIAQTKSELPQ 238 Query 237 AVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNT--------GDVWAGPVSLDELARP 288 AVP SG V+LNADDPAVAAMA++TAARVVRV R GDVWAGPVSLD LARP Sbjct 239 AVPASGVVILNADDPAVAAMAEVTAARVVRVGRATATGAGWAGPGDVWAGPVSLDRLARP 298 Query 289 RFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQV 348 +FT+HA DA A+VRLGV GDHQV+NALCA AVALECGASV QVAAAL A PVSRHRMQV Sbjct 299 QFTMHAGDAAAQVRLGVYGDHQVSNALCAGAVALECGASVSQVAAALAEAGPVSRHRMQV 358 Query 349 TTRGDGVTVIDDAYNANPDSMRAGLQALAWIAH---------QP---EATRRSWAVLGEM 396 +TR DGVTVIDDAYNANPDSMRAGLQALAWIA QP +RRSWAVLGEM Sbjct 359 STRPDGVTVIDDAYNANPDSMRAGLQALAWIARGEAESTAASQPGVRPQSRRSWAVLGEM 418 Query 397 AELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGAD 456 AELG DAI EHD IGRLAVRLDVSRLVVVGTGRS+SAM+HGAV+EG+WG+ Sbjct 419 AELGADAITEHDHIGRLAVRLDVSRLVVVGTGRSMSAMYHGAVMEGSWGT---------- 468 Query 457 RTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLG 493 AV+V D DAALALLRAE++PGDVVL+KASN+AGLG Sbjct 469 -EAVSVPDRDAALALLRAEIQPGDVVLIKASNSAGLG 504 >gi|336461947|gb|EGO40799.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium avium subsp. paratuberculosis S397] Length=519 Score = 706 bits (1822), Expect = 0.0, Method: Compositional matrix adjust. Identities = 419/519 (81%), Positives = 451/519 (87%), Gaps = 21/519 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MIELTVAQIA+IVGG +ADI+ DAA RRVTGTVEFDSRA+GPGGLFLALPGAR DGHDH Sbjct 1 MIELTVAQIADIVGGTLADITAPDAARRRVTGTVEFDSRAVGPGGLFLALPGARTDGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 A +AVAAGA VLAARPVGVPAIV PPV A + LAGVLEHD DGSGAAVLAALAKLA AV Sbjct 61 AEAAVAAGAVAVLAARPVGVPAIVAPPVDAADALAGVLEHDADGSGAAVLAALAKLARAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AA+LVAGGLTI+GITGSSGKTSTKDL+AAVLAPLGEVVAPPGSFNNELGHPWTVLRAT Sbjct 121 AAELVAGGLTIVGITGSSGKTSTKDLVAAVLAPLGEVVAPPGSFNNELGHPWTVLRATAD 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TDYL+LEM+ARH GNIAALAEIAPP++GVVLNVGTAHLGEFGSRE IA+TK+ELPQAVP Sbjct 181 TDYLVLEMSARHPGNIAALAEIAPPAVGVVLNVGTAHLGEFGSREAIARTKSELPQAVPA 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSR-DNT----GDVWAGPVSLDELARPRFTLHAH 295 SG VVLN DDP VAAMA++TAARVVRV R ++T DVWAGPVSLDELARP FTL+ Sbjct 241 SGVVVLNVDDPTVAAMAEVTAARVVRVGRAEHTEAGPSDVWAGPVSLDELARPGFTLYHR 300 Query 296 DA----QAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTR 351 A QA V+LGV GDHQV NALCAAAVALECGA+VEQV AAL A PVSRHRMQV+TR Sbjct 301 HAGGTRQARVQLGVSGDHQVGNALCAAAVALECGATVEQVVAALAGAGPVSRHRMQVSTR 360 Query 352 GDGVTVIDDAYNANPDSMRAGLQALAWIAH---QPEA-TRRSWAVLGEMAELGEDAIAEH 407 GDGVTVIDDAYNANPDSMRAGLQALAWIA +P A RRSWAVLGEMAELG+DAIAEH Sbjct 361 GDGVTVIDDAYNANPDSMRAGLQALAWIARGGAEPGAPARRSWAVLGEMAELGDDAIAEH 420 Query 408 DRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDA 467 DRIGRLAVRLDVSRLVVVGTGRS+SAMHHGAV+EG+WGS AD+ AVNV D +A Sbjct 421 DRIGRLAVRLDVSRLVVVGTGRSVSAMHHGAVMEGSWGS--------ADKGAVNVPDAEA 472 Query 468 ALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCG 506 A LLRAEL+PGDVVLVKASNAAGLGA+ADAL DD G Sbjct 473 ARELLRAELQPGDVVLVKASNAAGLGALADALARDDREG 511 >gi|118618799|ref|YP_907131.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium ulcerans Agy99] gi|118570909|gb|ABL05660.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium ulcerans Agy99] Length=525 Score = 685 bits (1768), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/515 (78%), Positives = 437/515 (85%), Gaps = 33/515 (6%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI+ TVA+IAEIVGG + DISPQ+A RRVTGTVEFDSRA+GPGGLFLALPGARADGHDH Sbjct 1 MIDYTVAEIAEIVGGTLVDISPQEAEQRRVTGTVEFDSRAVGPGGLFLALPGARADGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPV--AAPNVLAGVLEHDNDGSGAAVLAALAKLAT 118 AA+AVAAGA VLAARPVGV AIVV P + + L GVLEHD DGSGAAVLAALAKLA Sbjct 61 AAAAVAAGAVAVLAARPVGVSAIVVSPEPDSTADALTGVLEHDADGSGAAVLAALAKLAK 120 Query 119 AVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRAT 178 AVAA+L+AGGLTIIGITGSSGKTSTKDL+AAVL PLGEVVAPPGSFNNELGHPWTVLRAT Sbjct 121 AVAAELMAGGLTIIGITGSSGKTSTKDLVAAVLKPLGEVVAPPGSFNNELGHPWTVLRAT 180 Query 179 RRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAV 238 R TDYLILEM+ARH GNIAALA +APP+IGVVLNVGTAHLGEFGSRE+IAQTK+ELPQAV Sbjct 181 RSTDYLILEMSARHPGNIAALARVAPPAIGVVLNVGTAHLGEFGSREIIAQTKSELPQAV 240 Query 239 PHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNT--------GDVWAGPVSLDELARPRF 290 P SG V+LNADDPAVAAMA++TAARVVRV R GDVWAGPVSLD LARP+F Sbjct 241 PASGVVILNADDPAVAAMAEVTAARVVRVGRATATGAGWAGPGDVWAGPVSLDRLARPQF 300 Query 291 TLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTT 350 T+HA DA A+VRLGV GDHQV+NALCA AVALECGASV QVAAAL A PVSRHRM+V+T Sbjct 301 TMHAGDAAAQVRLGVYGDHQVSNALCAGAVALECGASVSQVAAALAEAGPVSRHRMRVST 360 Query 351 RGDGVTVIDDAYNANPDSMRAGLQALAWIAH---------QP---EATRRSWAVLGEMAE 398 R DGVTVIDDAYNANPDSMRAGLQALAWIA QP +RRSWAVLGEMAE Sbjct 361 RPDGVTVIDDAYNANPDSMRAGLQALAWIARGEAESTAASQPGVRPQSRRSWAVLGEMAE 420 Query 399 LGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRT 458 LG DAI EHD IGRLAVRLDVSRLVVVGTGRS+SA++HGAV+EG+WG+ Sbjct 421 LGADAITEHDHIGRLAVRLDVSRLVVVGTGRSMSAIYHGAVMEGSWGT-----------E 469 Query 459 AVNVADGDAALALLRAELRPGDVVLVKASNAAGLG 493 AV+V D DAALALLRAE++PGDVVL+KASN+AGLG Sbjct 470 AVSVPDRDAALALLRAEIQPGDVVLIKASNSAGLG 504 >gi|342859873|ref|ZP_08716526.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium colombiense CECT 3035] gi|342133005|gb|EGT86225.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium colombiense CECT 3035] Length=515 Score = 681 bits (1757), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/505 (81%), Positives = 437/505 (87%), Gaps = 24/505 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI+LT+AQIA+IVGG ++DISPQDAA R VTGTVEFDSRA+GPGGLFLALPGAR+DGHDH Sbjct 1 MIDLTLAQIADIVGGTLSDISPQDAARRHVTGTVEFDSRAVGPGGLFLALPGARSDGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 AASAVAAGA VLAARPVGVPAIVV P A AGVLEHD DGSGAAVLAALAKLA AV Sbjct 61 AASAVAAGAVAVLAARPVGVPAIVVTPAGASGSRAGVLEHDPDGSGAAVLAALAKLAKAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AA+LVAGGLTI+GITGSSGKTSTKDL+AAVLAPLGEVVAPPGSFNNELGHPWTVLRAT Sbjct 121 AAELVAGGLTIVGITGSSGKTSTKDLVAAVLAPLGEVVAPPGSFNNELGHPWTVLRATAD 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TD+L+LEM+ARH GNIAALA+IA PSIGVVLNVGTAHLGEFGSRE IAQTK+ELPQ+VP Sbjct 181 TDFLVLEMSARHPGNIAALADIATPSIGVVLNVGTAHLGEFGSREAIAQTKSELPQSVPA 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNT-----GDVWAGPVSLDELARPRFTLHAH 295 SG V+LNADDPAVAAMA +TAARVVRV R GD+WAGPVSLDELARPRFTLH Sbjct 241 SGVVILNADDPAVAAMADVTAARVVRVGRAERTNAGPGDLWAGPVSLDELARPRFTLHRR 300 Query 296 D----AQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTR 351 + Q VRLGV GDHQV NAL AAAVALECGA +EQVAAAL A PVSRHRMQVTTR Sbjct 301 EPSGVTQVPVRLGVYGDHQVGNALSAAAVALECGAGLEQVAAALAATGPVSRHRMQVTTR 360 Query 352 GDGVTVIDDAYNANPDSMRAGLQALAWIAH-------QPEATRRSWAVLGEMAELGEDAI 404 DGVTVIDDAYNANPDSMRAGLQALAWIA QP RRSWAVLGEMAELGEDAI Sbjct 361 ADGVTVIDDAYNANPDSMRAGLQALAWIARGGDDGGVQP---RRSWAVLGEMAELGEDAI 417 Query 405 AEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVAD 464 AEHDRIGRLAVRLDVSRLVVVG+GRS+SAMHHGAV+EG+WGS E+ D+ AVNVAD Sbjct 418 AEHDRIGRLAVRLDVSRLVVVGSGRSMSAMHHGAVMEGSWGSEES-----GDKGAVNVAD 472 Query 465 GDAALALLRAELRPGDVVLVKASNA 489 DAALALLRAE+RPGDVVLVKASN+ Sbjct 473 ADAALALLRAEVRPGDVVLVKASNS 497 >gi|15827430|ref|NP_301693.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanyl ligase (D-alanine:D-alanine-adding enzyme) [Mycobacterium leprae TN] gi|221229907|ref|YP_002503323.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase (D-alanine:D-alanine-adding enzyme) [Mycobacterium leprae Br4923] gi|20138886|sp|O69556.1|MURF_MYCLE RecName: Full=UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; AltName: Full=D-alanyl-D-alanine-adding enzyme; AltName: Full=UDP-MurNAc-pentapeptide synthetase gi|3080477|emb|CAA18672.1| udp-n-acetylmuramoylalanyl-d-glutamyl -2,6-diaminopimelate--d-alanyl-d-alanyl ligase [Mycobacterium leprae] gi|13092980|emb|CAC31291.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase (D-alanine:D-alanine-adding enzyme) [Mycobacterium leprae] gi|219933014|emb|CAR71005.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase (D-alanine:D-alanine-adding enzyme) [Mycobacterium leprae Br4923] Length=517 Score = 669 bits (1725), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/531 (76%), Positives = 433/531 (82%), Gaps = 35/531 (6%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI+LTVA++ EIVGGA+ DISP++AA RRVTG+VEFDSRA+GPGGLFLALPGAR+DGHDH Sbjct 1 MIDLTVARVTEIVGGALVDISPEEAAERRVTGSVEFDSRAVGPGGLFLALPGARSDGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVV--PPVAAPNVLAGVLEHDNDGSGAAVLAALAKLAT 118 AASA+AAGA VLAARPVGVPAIVV P L GVLEHD DGSGAAVLAALAKLA Sbjct 61 AASAIAAGAVAVLAARPVGVPAIVVAPDPRTGDGGLTGVLEHDADGSGAAVLAALAKLAK 120 Query 119 AVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRAT 178 AVAA+LVAGGLTIIGITGSSGKTSTKDL+A VL LGEVVAPP SFNNELGHPWTVLRAT Sbjct 121 AVAAELVAGGLTIIGITGSSGKTSTKDLVAVVLELLGEVVAPPESFNNELGHPWTVLRAT 180 Query 179 RRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAV 238 R TDYLILEM+AR GNIAALA IAPP IGVVLNVGTAHLGEFGSRE IA+TK ELPQA+ Sbjct 181 RSTDYLILEMSARRPGNIAALAAIAPPKIGVVLNVGTAHLGEFGSREAIARTKTELPQAI 240 Query 239 PHSGAVVLNADDPAVAAMAKLTAARVVRVSRD--------NTGDVWAGPVSLDELARPRF 290 SG V+LN DDPAVAAMA T ARV+RVSR N+ DVW GPVSLDELARPRF Sbjct 241 MQSGVVILNVDDPAVAAMADATVARVIRVSRGSYSHPGSPNSPDVWTGPVSLDELARPRF 300 Query 291 TLHAHDAQA---EVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQ 347 TLH D +A E++LGV GDHQV NALCAAAV LECGASVE+VA AL A PVSRHRMQ Sbjct 301 TLHTRDPRAGATEIQLGVYGDHQVANALCAAAVGLECGASVEEVAVALAATGPVSRHRMQ 360 Query 348 VTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAH-------QP-EATRRSWAVLGEMAEL 399 VTTR DGVTVIDD YNANPDSMRAGLQALAWIAH QP RRSWAVLGEMAEL Sbjct 361 VTTRADGVTVIDDTYNANPDSMRAGLQALAWIAHGGTHDKNQPGSCARRSWAVLGEMAEL 420 Query 400 GEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTA 459 GED+I EHDRIGRLAVRLDVSRLVVVG GRSI+AMH GAV+EG+WG Sbjct 421 GEDSITEHDRIGRLAVRLDVSRLVVVGGGRSINAMHRGAVMEGSWG-----------LET 469 Query 460 VNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVRP 510 VNVAD AAL LLRAE+RPGDVVL+KAS++ GLGA+AD LV D G++RP Sbjct 470 VNVADPAAALTLLRAEVRPGDVVLIKASHSVGLGALADVLVGD---GAIRP 517 >gi|120404499|ref|YP_954328.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase [Mycobacterium vanbaalenii PYR-1] gi|119957317|gb|ABM14322.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium vanbaalenii PYR-1] Length=526 Score = 664 bits (1714), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/507 (77%), Positives = 428/507 (85%), Gaps = 17/507 (3%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI +++A+IAEIVGG +AD+S +DAA VTGTVEFDSRA+ PGGLFLALPGAR+DGHD Sbjct 1 MIAMSLARIAEIVGGRLADVSDEDAARTVVTGTVEFDSRAVTPGGLFLALPGARSDGHDF 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPV----AAPNVLAGVLEHDNDGSGAAVLAALAKL 116 AA+AVAAGA VLAARPVGVPA+VV PV AAP AGVLEHD DGSGAAVLAALA+L Sbjct 61 AATAVAAGAVGVLAARPVGVPAVVVDPVRPDPAAPGT-AGVLEHDVDGSGAAVLAALARL 119 Query 117 ATAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLR 176 A+AVAA+LVAGGLTIIGITGSSGKTSTKDL+AAVLAPLGEVVAPPGSFNNELGHPWTVLR Sbjct 120 ASAVAAELVAGGLTIIGITGSSGKTSTKDLIAAVLAPLGEVVAPPGSFNNELGHPWTVLR 179 Query 177 ATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQ 236 ATR TDYL+LEM+ARH GNIAALA IA PSI VVLNVGTAHLGEFGSREVIA TK+ELPQ Sbjct 180 ATRSTDYLVLEMSARHPGNIAALARIAVPSIAVVLNVGTAHLGEFGSREVIAATKSELPQ 239 Query 237 AVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTG-DVWAGPVSLDELARPRFTLHAH 295 +VP SG V+LNADDPAVAAMA TAARVVRV R DV A VSLD LARP FTLH Sbjct 240 SVPESGVVILNADDPAVAAMADKTAARVVRVGRGAEALDVCADGVSLDALARPSFTLHTG 299 Query 296 DAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGV 355 A V L V GDHQV+NALCAAAVALECGA+ EQVAAAL A PVSRHRMQVT R DGV Sbjct 300 AADVPVTLAVHGDHQVSNALCAAAVALECGATPEQVAAALATAGPVSRHRMQVTAREDGV 359 Query 356 TVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAV 415 TVI+DAYNANPDSMRAGL+ALAW++ + RSWAVLGEMAELG+DAI EHDRIGRLAV Sbjct 360 TVINDAYNANPDSMRAGLKALAWMSRGGASKGRSWAVLGEMAELGDDAITEHDRIGRLAV 419 Query 416 RLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAE 475 RLDVSRL+VVG+GR +SAM HGAV+EG++GS A+ VAD DAAL +LRAE Sbjct 420 RLDVSRLIVVGSGRPMSAMLHGAVMEGSFGS-----------EAIPVADTDAALEILRAE 468 Query 476 LRPGDVVLVKASNAAGLGAVADALVAD 502 LRPGDVVLVKASN+AGLGA+ADALV+D Sbjct 469 LRPGDVVLVKASNSAGLGALADALVSD 495 >gi|118473094|ref|YP_888508.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium smegmatis str. MC2 155] gi|118174381|gb|ABK75277.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium smegmatis str. MC2 155] Length=509 Score = 659 bits (1699), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/508 (75%), Positives = 429/508 (85%), Gaps = 18/508 (3%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI++T+A+IAEIVGG +ADI+P+ AA VTGTVEFDSRA+GPGGLFLALPGAR+DGHD Sbjct 1 MIDMTIARIAEIVGGELADITPEQAAATHVTGTVEFDSRAVGPGGLFLALPGARSDGHDF 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 AA+AV +GA VLAARPVGVPAIVV P + +G LEHD DGSGAAVLAALA+LA AV Sbjct 61 AAAAVQSGAVAVLAARPVGVPAIVVRPDGGVDSASGALEHDTDGSGAAVLAALARLAAAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 A +L A GL IIG+TGSSGKTSTKDL+AAVLAPLGEVVAPPGSFNNELGHPWTVLRATR Sbjct 121 ANELAADGLKIIGVTGSSGKTSTKDLLAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRD 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TD+L+LEM+ARH GNIAALA IAPPS+ VVLNVGTAHLGEFGSRE IA+TKAELPQAV Sbjct 181 TDFLVLEMSARHPGNIAALAAIAPPSVAVVLNVGTAHLGEFGSREAIAKTKAELPQAVGP 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRD--NTGDVWAGPVSLDELARPRFTLHAHDAQ 298 SG V+LNADD AVAAMA+ T ARVVR+SRD + DVWAGPV+LDELARPRFTLH D + Sbjct 241 SGVVILNADDIAVAAMAEQTDARVVRISRDPGSDIDVWAGPVTLDELARPRFTLHTRDGE 300 Query 299 AEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVI 358 +V L V GDHQV+NALCAAAVALECGA+ +QVA AL AA P SRHRMQV+TR DGVTVI Sbjct 301 VDVNLAVHGDHQVSNALCAAAVALECGATPQQVADALAAAGPASRHRMQVSTRADGVTVI 360 Query 359 DDAYNANPDSMRAGLQALAWIAH-----QPEATRRSWAVLGEMAELGEDAIAEHDRIGRL 413 +DAYNANPDSMRAGL+ALAW+A QP RRSWAVLGEMAELG+DAI EHD IGR Sbjct 361 NDAYNANPDSMRAGLKALAWMARQTAGGQPGGKRRSWAVLGEMAELGDDAITEHDAIGRF 420 Query 414 AVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLR 473 AVRLDVSRL+VVG+GR+++AMHHGAV+EG+WGS E+T VAD DAAL +LR Sbjct 421 AVRLDVSRLLVVGSGRAMNAMHHGAVMEGSWGS-ESTM----------VADADAALTVLR 469 Query 474 AELRPGDVVLVKASNAAGLGAVADALVA 501 EL+PGDVVLVKASN+ GLGA+A+ALVA Sbjct 470 DELQPGDVVLVKASNSVGLGALAEALVA 497 >gi|254232315|ref|ZP_04925642.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase murF [Mycobacterium tuberculosis C] gi|124601374|gb|EAY60384.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase murF [Mycobacterium tuberculosis C] Length=514 Score = 634 bits (1634), Expect = 2e-179, Method: Compositional matrix adjust. Identities = 342/372 (92%), Positives = 346/372 (94%), Gaps = 13/372 (3%) Query 146 LMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPP 205 LM AVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPP Sbjct 149 LMPAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPP 208 Query 206 SIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVV 265 SIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVV Sbjct 209 SIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVV 268 Query 266 RVSRDNTGDVWAGPVSLDELAR-------PRFTLHAHDAQAEVRLGVCGDHQVTNALCAA 318 RVSRDNTGDVWAGPVSL+ + + PR D+ G HQVTNALCAA Sbjct 269 RVSRDNTGDVWAGPVSLERIGQAALYAACPRCPSRGPDS------GSAATHQVTNALCAA 322 Query 319 AVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAW 378 AVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAW Sbjct 323 AVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAW 382 Query 379 IAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGA 438 IAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGA Sbjct 383 IAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGA 442 Query 439 VLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADA 498 VLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADA Sbjct 443 VLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADA 502 Query 499 LVADDTCGSVRP 510 LVADDTCGSVRP Sbjct 503 LVADDTCGSVRP 514 >gi|145223571|ref|YP_001134249.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase [Mycobacterium gilvum PYR-GCK] gi|145216057|gb|ABP45461.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium gilvum PYR-GCK] Length=504 Score = 611 bits (1576), Expect = 9e-173, Method: Compositional matrix adjust. Identities = 385/515 (75%), Positives = 425/515 (83%), Gaps = 17/515 (3%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MIE+++ +IAEIVGG +AD+S +A RVTGTVEFDSRA+ GGLFLALPGAR+DGHD Sbjct 1 MIEMSLRRIAEIVGGRLADVSADEADRLRVTGTVEFDSRAVTAGGLFLALPGARSDGHDF 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNV---LAGVLEHDNDGSGAAVLAALAKLA 117 AA+AVA+GA VLAARPVGVPA+VV PVA + AGVLEHD DGSGAAVLAALA+LA Sbjct 61 AATAVASGAVAVLAARPVGVPAVVVDPVAPQHGAGGTAGVLEHDADGSGAAVLAALARLA 120 Query 118 TAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRA 177 AVAA+LVAGGLTI+GITGSSGKTSTKDL+AAVLAPLGEV+APPGSFNNELGHPWTVLRA Sbjct 121 AAVAAELVAGGLTIVGITGSSGKTSTKDLIAAVLAPLGEVIAPPGSFNNELGHPWTVLRA 180 Query 178 TRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQA 237 T TDYL+LEM+ARH GNIAALA IAPPSIG VLNVGTAHLGEFGSRE IA TK+ELPQA Sbjct 181 TESTDYLVLEMSARHPGNIAALARIAPPSIGAVLNVGTAHLGEFGSREAIAATKSELPQA 240 Query 238 VPHSGAVVLNADDPAVAAMAKLTAARVVRVSRD---NTGDVWAGPVSLDELARPRFTLHA 294 VP SG V+LNADDP VAAMA TAARVVRV R T DV A V+LD LARP FTLHA Sbjct 241 VPQSGVVILNADDPVVAAMADKTAARVVRVGRSADARTLDVRADGVTLDPLARPAFTLHA 300 Query 295 HDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDG 354 Q V L V GDHQV+NAL AAAVALECGA++ QVA AL AA PVSRHRMQV+TR DG Sbjct 301 GGEQVPVTLAVHGDHQVSNALVAAAVALECGATLTQVAGALAAAGPVSRHRMQVSTRSDG 360 Query 355 VTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLA 414 VTVI+DAYNANPDSM AGL+ALAW++ Q RS+AVLGEMAELGED I EHDRIGRLA Sbjct 361 VTVINDAYNANPDSMTAGLKALAWMSRQNPEGSRSFAVLGEMAELGEDTITEHDRIGRLA 420 Query 415 VRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRA 474 VRLDVSRLVVVG+GR +SAM HGAV+EG+WGS EAT VAD DAALALLR Sbjct 421 VRLDVSRLVVVGSGRPMSAMLHGAVMEGSWGS-EATP----------VADADAALALLRD 469 Query 475 ELRPGDVVLVKASNAAGLGAVADALVADDTCGSVR 509 ELRPGDVVLVKASN+AGLGA+ADALV++ G R Sbjct 470 ELRPGDVVLVKASNSAGLGALADALVSEQLPGDGR 504 >gi|333990379|ref|YP_004522993.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-26- diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium sp. JDM601] gi|333486347|gb|AEF35739.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-26- diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium sp. JDM601] Length=501 Score = 611 bits (1575), Expect = 1e-172, Method: Compositional matrix adjust. Identities = 377/507 (75%), Positives = 411/507 (82%), Gaps = 15/507 (2%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI LTVA+IA IVGG +ADISP+ AA V+G+VEFDSR I G LFLALPGARADGHDH Sbjct 1 MIALTVAEIAAIVGGRLADISPEQAARTVVSGSVEFDSRRITAGSLFLALPGARADGHDH 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDN-DGSGAAVLAALAKLATA 119 AASAVAAGA VLAARPVGVPAIVV P +G LEHD+ GSGA VLAALA LA A Sbjct 61 AASAVAAGAVAVLAARPVGVPAIVVDPGPKAASRSGALEHDDASGSGATVLAALATLAAA 120 Query 120 VAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATR 179 VAA+LVA GL IIG+TGSSGKTSTKDL+A VLAPLG+VVAPPGSFNNELGHPWTVLRA Sbjct 121 VAARLVAEGLRIIGVTGSSGKTSTKDLIATVLAPLGQVVAPPGSFNNELGHPWTVLRADE 180 Query 180 RTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVP 239 TD+L+LE++ARH GNIA LA IAPP + VVLNVG+AHLGEFGSRE IA+TKAEL QAVP Sbjct 181 HTDFLVLELSARHRGNIAELAAIAPPQLAVVLNVGSAHLGEFGSREAIAETKAELVQAVP 240 Query 240 HSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHA-HDAQ 298 SG V+LN DD AVAAMA T ARVVRVSR DVWA V LDELARPRF LHA +A Sbjct 241 ESGVVILNVDDSAVAAMADKTVARVVRVSRSAPADVWADAVVLDELARPRFALHAGGEAD 300 Query 299 AEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVI 358 V LGV GDHQV NALCAAAVALECGA+ +QVA AL A P S HRMQV+TR DGVTVI Sbjct 301 VTVSLGVSGDHQVGNALCAAAVALECGATPQQVADALAGAGPASGHRMQVSTRADGVTVI 360 Query 359 DDAYNANPDSMRAGLQALAWIA--HQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVR 416 DD+YNANPDSMRA LQALAWIA P A R SWAVLGEMAELGEDAI+EHDRIGRLAVR Sbjct 361 DDSYNANPDSMRAALQALAWIARGENPGAKRHSWAVLGEMAELGEDAISEHDRIGRLAVR 420 Query 417 LDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAEL 476 LDVSRL+VVG GR++ AMHHGAV+EG+WG+ EATA V D DAALALLRAEL Sbjct 421 LDVSRLIVVGVGRAMGAMHHGAVMEGSWGA-EATA----------VQDVDAALALLRAEL 469 Query 477 RPGDVVLVKASNAAGLGAVADALVADD 503 R GDVVLVKASN+AGL A+ADALV+DD Sbjct 470 RSGDVVLVKASNSAGLTALADALVSDD 496 >gi|108800226|ref|YP_640423.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium sp. MCS] gi|119869354|ref|YP_939306.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium sp. KMS] gi|126435849|ref|YP_001071540.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase [Mycobacterium sp. JLS] gi|108770645|gb|ABG09367.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium sp. MCS] gi|119695443|gb|ABL92516.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium sp. KMS] gi|126235649|gb|ABN99049.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase [Mycobacterium sp. JLS] Length=497 Score = 609 bits (1571), Expect = 3e-172, Method: Compositional matrix adjust. Identities = 379/501 (76%), Positives = 429/501 (86%), Gaps = 12/501 (2%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MIELT+A++AEIVGG +ADI+P+DAA R+TGTVEFDSRA+ GGLFLALPGAR+DGHD Sbjct 1 MIELTLARVAEIVGGRLADITPEDAAATRITGTVEFDSRAVTAGGLFLALPGARSDGHDF 60 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 AA+AVAAGAA VLAARPVGVPA+VVPP A P +GVLEHD DG+GAAVLAALA+LA AV Sbjct 61 AAAAVAAGAAAVLAARPVGVPAVVVPPAAGPEG-SGVLEHDTDGAGAAVLAALARLAAAV 119 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AA+LV GGL I+GITGSSGKTSTKDL+AAVLAPLGEV+APPGSFNNELGHPWTVLRA R Sbjct 120 AAELVDGGLRIVGITGSSGKTSTKDLVAAVLAPLGEVIAPPGSFNNELGHPWTVLRADRS 179 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TD+L+LEM+ARH GNIAALA IAPPSI VVLNVGTAHLGEFGSRE IA TK+ELPQAVP Sbjct 180 TDFLVLEMSARHPGNIAALAAIAPPSIAVVLNVGTAHLGEFGSREAIAATKSELPQAVPE 239 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE 300 SG V+LNADD AVAAMA++TAARVVRVSR+ D+WA V+LDELARPRFTLHA + Sbjct 240 SGVVILNADDSAVAAMAEVTAARVVRVSREPGADIWADAVTLDELARPRFTLHAAGGEVP 299 Query 301 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD 360 V L V GDHQV+NALCAAAVALECGA+++QVAAAL A PVSRHRMQVTTR DGVTV++D Sbjct 300 VNLAVHGDHQVSNALCAAAVALECGATLDQVAAALAGAGPVSRHRMQVTTREDGVTVVND 359 Query 361 AYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVS 420 AYNANPDSMRAGL+ALAW++ A RRSWAVLGEMAELG+D+I+EHD IGRLAVRLDVS Sbjct 360 AYNANPDSMRAGLKALAWMSRGGAAKRRSWAVLGEMAELGDDSISEHDSIGRLAVRLDVS 419 Query 421 RLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGD 480 RLVVVGTGRS SAMH GAV+EG+WG+ EAT AD ++D EL+PGD Sbjct 420 RLVVVGTGRSASAMHQGAVMEGSWGA-EATRVDDADAALALLSD----------ELQPGD 468 Query 481 VVLVKASNAAGLGAVADALVA 501 VVLVKASN+AGLGA+AD+L A Sbjct 469 VVLVKASNSAGLGALADSLTA 489 >gi|315443918|ref|YP_004076797.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium sp. Spyr1] gi|315262221|gb|ADT98962.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium sp. Spyr1] Length=501 Score = 605 bits (1559), Expect = 8e-171, Method: Compositional matrix adjust. Identities = 382/512 (75%), Positives = 422/512 (83%), Gaps = 17/512 (3%) Query 4 LTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDHAAS 63 +++ +IAEIVGG +AD+S +A RVTGTVEFDSRA+ GGLFLALPGAR+DGHD AA+ Sbjct 1 MSLRRIAEIVGGRLADVSADEADRLRVTGTVEFDSRAVTAGGLFLALPGARSDGHDFAAT 60 Query 64 AVAAGAAVVLAARPVGVPAIVVPPVAAPNV---LAGVLEHDNDGSGAAVLAALAKLATAV 120 AVA+GA VLAARPVGVPA+VV PVA + AGVLEHD DGSGAAVLAALA+LA AV Sbjct 61 AVASGAVAVLAARPVGVPAVVVDPVAPQHGAGGTAGVLEHDADGSGAAVLAALARLAAAV 120 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 AA+LVAGGLTI+GITGSSGKTSTKDL+AAVLAPLGEV+APPGSFNNELGHPWTVLRAT Sbjct 121 AAELVAGGLTIVGITGSSGKTSTKDLIAAVLAPLGEVIAPPGSFNNELGHPWTVLRATES 180 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 TDYL+LEM+ARH GNIAALA IAPPSIG VLNVGTAHLGEFGSRE IA TK+ELPQAVP Sbjct 181 TDYLVLEMSARHPGNIAALARIAPPSIGAVLNVGTAHLGEFGSREAIAATKSELPQAVPQ 240 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRD---NTGDVWAGPVSLDELARPRFTLHAHDA 297 SG V+LNADDP VAAMA TAARVVRV R T DV A V+LD LARP FTLHA Sbjct 241 SGVVILNADDPVVAAMADKTAARVVRVGRSADARTLDVRADGVTLDPLARPAFTLHAGGE 300 Query 298 QAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTV 357 Q V L V GDHQV+NAL AAAVALECGA++ QVA AL AA PVSRHRMQV+TR DGVTV Sbjct 301 QVPVTLAVHGDHQVSNALVAAAVALECGATLTQVAGALAAAGPVSRHRMQVSTRSDGVTV 360 Query 358 IDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRL 417 I+DAYNANPDSM AGL+ALAW++ Q RS+AVLGEMAELGED I EHDRIGRLAVRL Sbjct 361 INDAYNANPDSMTAGLKALAWMSRQNPEGSRSFAVLGEMAELGEDTITEHDRIGRLAVRL 420 Query 418 DVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELR 477 DVSRLVVVG+GR +SAM HGAV+EG+WGS EAT VAD DAALALLR ELR Sbjct 421 DVSRLVVVGSGRPMSAMLHGAVMEGSWGS-EATP----------VADADAALALLRDELR 469 Query 478 PGDVVLVKASNAAGLGAVADALVADDTCGSVR 509 PGDVVLVKASN+AGLGA+ADALV++ G R Sbjct 470 PGDVVLVKASNSAGLGALADALVSEQLPGDGR 501 >gi|289447785|ref|ZP_06437529.1| phospho-N-acetylMuramoyl-pentapeptidetransferase MurX [Mycobacterium tuberculosis CPHL_A] gi|289420743|gb|EFD17944.1| phospho-N-acetylMuramoyl-pentapeptidetransferase MurX [Mycobacterium tuberculosis CPHL_A] Length=301 Score = 587 bits (1512), Expect = 2e-165, Method: Compositional matrix adjust. Identities = 299/301 (99%), Positives = 300/301 (99%), Gaps = 0/301 (0%) Query 210 VLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSR 269 +LNVG AHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSR Sbjct 1 MLNVGPAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSR 60 Query 270 DNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVE 329 DNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVE Sbjct 61 DNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVE 120 Query 330 QVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRS 389 QVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRS Sbjct 121 QVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRS 180 Query 390 WAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEA 449 WAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEA Sbjct 181 WAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEA 240 Query 450 TADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVR 509 TADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVR Sbjct 241 TADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVR 300 Query 510 P 510 P Sbjct 301 P 301 >gi|254821976|ref|ZP_05226977.1| hypothetical protein MintA_18732 [Mycobacterium intracellulare ATCC 13950] Length=419 Score = 586 bits (1511), Expect = 3e-165, Method: Compositional matrix adjust. Identities = 345/427 (81%), Positives = 373/427 (88%), Gaps = 21/427 (4%) Query 97 VLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGE 156 +LEHD DGSGAAVLAALAKLA VAA+LVAGGL I+GITGSSGKTSTKDL+AAVL PLGE Sbjct 1 MLEHDPDGSGAAVLAALAKLAQVVAAELVAGGLRIVGITGSSGKTSTKDLVAAVLKPLGE 60 Query 157 VVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTA 216 VVAPPGSFNNELGHPWTVLRAT TD+L+LEM+ARH GNIAALAEIAPP+IGVVLNVGTA Sbjct 61 VVAPPGSFNNELGHPWTVLRATPETDFLVLEMSARHPGNIAALAEIAPPAIGVVLNVGTA 120 Query 217 HLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSR-DNT--- 272 HLGEFGSRE IAQTK+ELPQ+VP SG V+LNADDPAVAAMA +TAARVVRVSR +NT Sbjct 121 HLGEFGSREAIAQTKSELPQSVPESGVVILNADDPAVAAMAGVTAARVVRVSRAENTSAG 180 Query 273 -GDVWAGPVSLDELARPRFTLHAHDA----QAEVRLGVCGDHQVTNALCAAAVALECGAS 327 +WAGPVSLDE+ARP FTLH DA QA+VRLGV GDHQVTNALCAAAVALECGA Sbjct 181 PSQLWAGPVSLDEVARPCFTLHHRDASGTTQAQVRLGVYGDHQVTNALCAAAVALECGAD 240 Query 328 VEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAH----QP 383 V+QVAAAL A PVSRHRM VTTR DGVTVIDDAYNANPDSMRAGLQALAWIAH +P Sbjct 241 VDQVAAALAGAGPVSRHRMHVTTRADGVTVIDDAYNANPDSMRAGLQALAWIAHGGGDRP 300 Query 384 EATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGA 443 RRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVG+GRS+SAMHHGAV+EG+ Sbjct 301 AEKRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGSGRSMSAMHHGAVMEGS 360 Query 444 WGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADD 503 WGS AD+ AVNVADG+AALALLRAEL+PGDVVLVKASNAAGLGA+ADALV+ Sbjct 361 WGS--------ADKGAVNVADGEAALALLRAELQPGDVVLVKASNAAGLGALADALVSQG 412 Query 504 TCGSVRP 510 + G RP Sbjct 413 SQGGARP 419 >gi|296166025|ref|ZP_06848476.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898624|gb|EFG78179.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=444 Score = 577 bits (1486), Expect = 2e-162, Method: Compositional matrix adjust. Identities = 346/425 (82%), Positives = 367/425 (87%), Gaps = 20/425 (4%) Query 94 LAGVLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAP 153 LAGVLEHD DGSGAAVLAALAKLA AVAA+LVAGGLTIIGITGSSGKTSTKDL+AAVL P Sbjct 4 LAGVLEHDADGSGAAVLAALAKLAKAVAAELVAGGLTIIGITGSSGKTSTKDLVAAVLEP 63 Query 154 LGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNV 213 LGEVVAPPGSFNNELGHPWTVLRATRRTDYL+LEM+ARH GNIAALAEIAPP+IGVVLNV Sbjct 64 LGEVVAPPGSFNNELGHPWTVLRATRRTDYLVLEMSARHPGNIAALAEIAPPAIGVVLNV 123 Query 214 GTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDN-- 271 GTAHLGEFGSRE IA+TK+ELPQAVP SG VVLN DDP VAAMA++T A VVRVSR + Sbjct 124 GTAHLGEFGSREAIARTKSELPQAVPSSGVVVLNVDDPMVAAMARVTDAWVVRVSRSSHT 183 Query 272 ---TGDVWAGPVSLDELARPRFTLHAHDAQAE----VRLGVCGDHQVTNALCAAAVALEC 324 DVWA VSLDELARPRFTLHA +AQ V+LGV GDHQVTNALCA AVAL+C Sbjct 184 DSGPSDVWADGVSLDELARPRFTLHAMNAQGTVEVGVQLGVYGDHQVTNALCAGAVALQC 243 Query 325 GASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPE 384 GA+VEQVA AL A PVSRHRM VTTR DGVTVIDDAYNANPDSMRAGLQALAWIAH Sbjct 244 GATVEQVATALEQAGPVSRHRMHVTTRADGVTVIDDAYNANPDSMRAGLQALAWIAHGAG 303 Query 385 A--TRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEG 442 A RRSWAVLGEMAELG+DA+AEHDRIGRLAVRLDVSRLVVVGTGRS+SAMHHGAV+EG Sbjct 304 AGERRRSWAVLGEMAELGDDAVAEHDRIGRLAVRLDVSRLVVVGTGRSMSAMHHGAVMEG 363 Query 443 AWG-SGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVA 501 +WG SGE R AV+VAD DAALALLRAELRPGDVVLVKASNAAGLG +ADAL Sbjct 364 SWGASGE--------RGAVSVADADAALALLRAELRPGDVVLVKASNAAGLGTLADALAR 415 Query 502 DDTCG 506 DD G Sbjct 416 DDREG 420 >gi|339295073|gb|AEJ47184.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase murF [Mycobacterium tuberculosis CCDC5079] Length=293 Score = 575 bits (1481), Expect = 1e-161, Method: Compositional matrix adjust. Identities = 292/293 (99%), Positives = 293/293 (100%), Gaps = 0/293 (0%) Query 218 LGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWA 277 +GEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWA Sbjct 1 MGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWA 60 Query 278 GPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTA 337 GPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTA Sbjct 61 GPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTA 120 Query 338 APPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMA 397 APPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMA Sbjct 121 APPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMA 180 Query 398 ELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADR 457 ELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADR Sbjct 181 ELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADR 240 Query 458 TAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVRP 510 TAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVRP Sbjct 241 TAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVADDTCGSVRP 293 >gi|312140146|ref|YP_004007482.1| UDP-N-acetylmuramoyl-tripeptide-d-alanyl-d-alanin e ligase murf [Rhodococcus equi 103S] gi|311889485|emb|CBH48802.1| UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase MurF [Rhodococcus equi 103S] Length=506 Score = 534 bits (1375), Expect = 2e-149, Method: Compositional matrix adjust. Identities = 320/513 (63%), Positives = 374/513 (73%), Gaps = 19/513 (3%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI +T+AQIA+ VGG + D+ A V+GTVEFDSR I PGGLFLALPGAR DGHDH Sbjct 1 MIPMTLAQIAQAVGGTLHDVDDPSAT---VSGTVEFDSRKITPGGLFLALPGARVDGHDH 57 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 AA AVAAGA VLAARPVGVPAIVV P+ A LEHD DGSGAAVLAAL KLA A Sbjct 58 AAGAVAAGAVAVLAARPVGVPAIVVEPLGTSGNGALALEHDRDGSGAAVLAALGKLARAS 117 Query 121 AAQLVA-GGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATR 179 +L GLT++G+TGSSGKTSTKDL+AAVL+PLG VVAPPGSFNNELGHPWT LRA Sbjct 118 VDRLTTESGLTVVGVTGSSGKTSTKDLLAAVLSPLGSVVAPPGSFNNELGHPWTALRADA 177 Query 180 RTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVP 239 T +L+LEM+AR G+IAALAEIAPP IGVVLNVGTAHLGEFGSRE IA+TK ELP ++P Sbjct 178 DTRFLVLEMSARGRGHIAALAEIAPPRIGVVLNVGTAHLGEFGSREAIAETKGELPASLP 237 Query 240 HS---GAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHD 296 + G VLNADDP VAAMA T ARVV V DV A V LD+ AR FTL Sbjct 238 SAADGGVAVLNADDPLVAAMADRTEARVVMVGLSGNADVRATDVRLDDQARASFTLTCAA 297 Query 297 AQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVT 356 V L V G+H V NAL AAAVALECGA+++Q+AAAL A PVS RM+V R DGVT Sbjct 298 GAVPVTLAVHGEHHVGNALAAAAVALECGATLDQIAAALGGAAPVSARRMEVRDRSDGVT 357 Query 357 VIDDAYNANPDSMRAGLQALAWIAHQPEA-TRRSWAVLGEMAELGEDAIAEHDRIGRLAV 415 V++D+YNANPDSMRA ++AL +A RR+WAVLGEMAELG +++ EHD IGR AV Sbjct 358 VVNDSYNANPDSMRAAIKALVSMARSGRGPARRTWAVLGEMAELGPESVVEHDAIGRFAV 417 Query 416 RLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAE 475 RLDV++L++VG GR + AM+ GAV+EG+WG A++V DG +A+ALL E Sbjct 418 RLDVTKLILVGPGRPVRAMYQGAVMEGSWGD-----------EAIHVPDGASAIALLEQE 466 Query 476 LRPGDVVLVKASNAAGLGAVADALVADDTCGSV 508 LR GD+VLVKAS + GL VADA++A GSV Sbjct 467 LRAGDLVLVKASQSIGLWEVADAVLAAPVAGSV 499 >gi|325676973|ref|ZP_08156645.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Rhodococcus equi ATCC 33707] gi|325552273|gb|EGD21963.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Rhodococcus equi ATCC 33707] Length=506 Score = 531 bits (1369), Expect = 8e-149, Method: Compositional matrix adjust. Identities = 320/513 (63%), Positives = 374/513 (73%), Gaps = 19/513 (3%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI +T+AQIA+ VGG + D+ A V+GTVEFDSR I GGLFLALPGAR DGHDH Sbjct 1 MIPMTLAQIAQAVGGTLHDVDDPSAT---VSGTVEFDSRKITSGGLFLALPGARVDGHDH 57 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 AA AVAAGA VLAARPVGVPAIVV P+ A A LEHD DGSGAAVLAAL KLA A Sbjct 58 AAGAVAAGAVAVLAARPVGVPAIVVEPLGASGNGALALEHDRDGSGAAVLAALGKLARAS 117 Query 121 AAQLVA-GGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATR 179 +L GLT++G+TGSSGKTSTKDL+AAVL+PLG VVAPPGSFNNELGHPWT LRA Sbjct 118 VDRLTTESGLTVVGVTGSSGKTSTKDLLAAVLSPLGSVVAPPGSFNNELGHPWTALRADA 177 Query 180 RTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVP 239 T +L+LEM+AR G+IAALAEIAPP IGVVLNVGTAHLGEFGSRE IA+TK ELP ++P Sbjct 178 DTRFLVLEMSARGRGHIAALAEIAPPRIGVVLNVGTAHLGEFGSREAIAETKGELPASLP 237 Query 240 HS---GAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHD 296 + G VLNADDP VAAMA T ARVV V DV A V LD+ AR FTL Sbjct 238 SAADGGVAVLNADDPLVAAMADRTEARVVMVGLSGNADVRATDVRLDDQARASFTLTCAA 297 Query 297 AQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVT 356 V L V G+H V NAL AAAVALECGA+++Q+AAAL A PVS RM+V R DGVT Sbjct 298 GAVPVTLAVHGEHHVGNALAAAAVALECGATLDQIAAALGGAAPVSARRMEVRDRSDGVT 357 Query 357 VIDDAYNANPDSMRAGLQALAWIAHQPEA-TRRSWAVLGEMAELGEDAIAEHDRIGRLAV 415 V++D+YNANPDSMRA ++AL +A RR+WAVLGEMAELG +++ EHD IGR AV Sbjct 358 VVNDSYNANPDSMRAAIKALVSMARSGRGPARRTWAVLGEMAELGPESVVEHDAIGRFAV 417 Query 416 RLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAE 475 RLDV++L++VG GR + AM+ GAV+EG+WG A++V DG +A+ALL E Sbjct 418 RLDVTKLILVGPGRPVRAMYQGAVMEGSWGD-----------EAIHVPDGASAIALLEQE 466 Query 476 LRPGDVVLVKASNAAGLGAVADALVADDTCGSV 508 LR GD+VLVKAS + GL VADA++A GSV Sbjct 467 LRAGDLVLVKASQSIGLWEVADAVLAAPVAGSV 499 >gi|169629089|ref|YP_001702738.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF [Mycobacterium abscessus ATCC 19977] gi|169241056|emb|CAM62084.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase MurF [Mycobacterium abscessus] Length=491 Score = 531 bits (1369), Expect = 9e-149, Method: Compositional matrix adjust. Identities = 345/497 (70%), Positives = 383/497 (78%), Gaps = 11/497 (2%) Query 4 LTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDHAAS 63 +TVA+IAEIVGG + IS Q+A RVTGTVEFDSR + PGGLFLALPGARADGHDHA Sbjct 1 MTVAEIAEIVGGRLDGISAQEARQARVTGTVEFDSRQVSPGGLFLALPGARADGHDHARG 60 Query 64 AVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAVAAQ 123 A AGA VLAARPVGVPAIVVPP LEHD+DGSGAAVLAA A LA VA + Sbjct 61 AAEAGAVAVLAARPVGVPAIVVPPTGVARTEVSALEHDSDGSGAAVLAATAALAAEVARR 120 Query 124 LVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDY 183 L A GL I+GITGSSGKTSTKDL+AAVL+PLGEVVAPPGSFNNELGHPWTVLRAT T + Sbjct 121 LTARGLRIVGITGSSGKTSTKDLIAAVLSPLGEVVAPPGSFNNELGHPWTVLRATESTKF 180 Query 184 LILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGA 243 L+LE++AR GNIA LA IAPPSIGVVLNVGTAHLGEFGSR+ IA TK ELPQ++ G Sbjct 181 LVLELSARRPGNIAELAAIAPPSIGVVLNVGTAHLGEFGSRQAIADTKGELPQSLSGGGV 240 Query 244 VVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRL 303 VLNADD AVAAMA T ARVVR S + D+WA VS+D+LAR RFTLHA V+L Sbjct 241 AVLNADDAAVAAMAAKTPARVVRTSVHHPADIWATEVSVDDLARARFTLHAGQDSVPVQL 300 Query 304 GVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYN 363 V G+H V+NAL AAAVALECGA++ QVAAAL A PVSR RM+V+TR DGVTVI+DAYN Sbjct 301 AVHGEHHVSNALAAAAVALECGATLAQVAAALAGAGPVSRRRMEVSTRDDGVTVINDAYN 360 Query 364 ANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLV 423 ANPDSM AGL+AL +A RRSWAVLGEMAELG DAI+EHDRIGR AVRLDVSRLV Sbjct 361 ANPDSMMAGLKALVSMARHGGEPRRSWAVLGEMAELGPDAISEHDRIGRAAVRLDVSRLV 420 Query 424 VVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVL 483 VVGTGRS AMH GAV+EG+WGS AV V D AA +LL +EL GDVVL Sbjct 421 VVGTGRSQRAMHAGAVMEGSWGS-----------EAVLVDDPAAAASLLASELAAGDVVL 469 Query 484 VKASNAAGLGAVADALV 500 VKAS +AGL VAD L+ Sbjct 470 VKASRSAGLWVVADELL 486 >gi|111018105|ref|YP_701077.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Rhodococcus jostii RHA1] gi|110817635|gb|ABG92919.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Rhodococcus jostii RHA1] Length=504 Score = 524 bits (1349), Expect = 2e-146, Method: Compositional matrix adjust. Identities = 319/510 (63%), Positives = 369/510 (73%), Gaps = 21/510 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI +T+A+IAEIVGG + D++ A VTGTVEFDSR + GGLFLALPGA DGHDH Sbjct 1 MIPMTLARIAEIVGGELHDVADPSA---EVTGTVEFDSRKVTAGGLFLALPGAHVDGHDH 57 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAA--PNVLAGVLEHDNDGSGAAVLAALAKLAT 118 AASAV AG VLAARPVGVPAIVV P + P+ A LEHD DGSGAAVLAALAKLA Sbjct 58 AASAVEAGVVAVLAARPVGVPAIVVTPTPSDVPS-KAMALEHDTDGSGAAVLAALAKLAR 116 Query 119 AVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRAT 178 A L A GLT++G+TGS+GKTSTKDL+AAVL PLG VVAPPGSFNNELGHPWT LRA Sbjct 117 ASVDGLTAKGLTVVGVTGSAGKTSTKDLLAAVLRPLGPVVAPPGSFNNELGHPWTALRAD 176 Query 179 RRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAV 238 T +L+LEM+AR G+IA+LA IAPP IGVVLNVGTAHLGEFGSR+ IA K EL +++ Sbjct 177 ADTGFLVLEMSARGRGHIASLANIAPPKIGVVLNVGTAHLGEFGSRDAIAAAKGELAESL 236 Query 239 P---HSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAH 295 P G +LNADDP VAAMA T+ARVV V R + V A + LDE AR RFTL A Sbjct 237 PSADEGGVAILNADDPLVAAMAPRTSARVVLVGRSESAHVRATDIVLDEKARARFTLTAP 296 Query 296 DAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGV 355 V L V G+HQV NAL AAAVALECGA +EQ+A AL+ A VS RM V R DGV Sbjct 297 TGSVAVELAVHGEHQVGNALAAAAVALECGADLEQIAQALSGAAAVSARRMDVRDRPDGV 356 Query 356 TVIDDAYNANPDSMRAGLQALAWIAHQPE-ATRRSWAVLGEMAELGEDAIAEHDRIGRLA 414 TV++D+YNANPDSMRA L+AL +A A RRSWAVLGEMAELG +++ EHD IGR A Sbjct 357 TVVNDSYNANPDSMRAALKALVSMARSGRGAARRSWAVLGEMAELGPESVVEHDAIGRFA 416 Query 415 VRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRA 474 VRLDVSRL++VGTGR AMH GAV+EG+WG ++ V D A+ALL A Sbjct 417 VRLDVSRLIIVGTGRPARAMHQGAVMEGSWG-----------EESILVPDIAGAVALLEA 465 Query 475 ELRPGDVVLVKASNAAGLGAVADALVADDT 504 EL PGD+VLVKAS + GL VAD ++A T Sbjct 466 ELAPGDLVLVKASQSIGLWEVADTVLAGST 495 >gi|226360234|ref|YP_002778012.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase [Rhodococcus opacus B4] gi|226238719|dbj|BAH49067.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase [Rhodococcus opacus B4] Length=504 Score = 519 bits (1336), Expect = 6e-145, Method: Compositional matrix adjust. Identities = 320/511 (63%), Positives = 371/511 (73%), Gaps = 23/511 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI +T+A+IAEIVGG + D++ A VTGTVEFDSR + GGLFLALPGAR DGHDH Sbjct 1 MIPMTLARIAEIVGGELHDVADPSA---EVTGTVEFDSRKVTAGGLFLALPGARVDGHDH 57 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNV---LAGVLEHDNDGSGAAVLAALAKLA 117 AASAV AGA VLAARPVGVPA+VV P AP A LEHD DGSGAAVLAALAKLA Sbjct 58 AASAVEAGAVAVLAARPVGVPAVVVSP--APGTGPSKAMALEHDTDGSGAAVLAALAKLA 115 Query 118 TAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRA 177 A L A GLT++G+TGS+GKTSTKDL+AAVL PLG VVAPPGSFNNELGHPWT LRA Sbjct 116 RASVDDLTAKGLTVVGVTGSAGKTSTKDLLAAVLRPLGPVVAPPGSFNNELGHPWTALRA 175 Query 178 TRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQA 237 T +L+LEM+AR G+IA+LA IAPP IGVVLNVGTAHLGEFGSR+ IA K ELP++ Sbjct 176 DAGTGFLVLEMSARDRGHIASLAAIAPPKIGVVLNVGTAHLGEFGSRDAIAAAKGELPES 235 Query 238 VPHS---GAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHA 294 +P + G +LNADDP V AMA T+ARVV V R + V A + LDE AR RFTL Sbjct 236 LPSADDGGVAILNADDPLVVAMAPRTSARVVLVGRSESAHVRATDIVLDERARARFTLTT 295 Query 295 HDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDG 354 V L V G+HQV NAL AAAVALECGA ++Q+A AL+AA VS RM V R DG Sbjct 296 AAGSVPVELAVHGEHQVGNALAAAAVALECGADLDQIARALSAAAAVSGRRMDVRDRPDG 355 Query 355 VTVIDDAYNANPDSMRAGLQALAWIAHQ-PEATRRSWAVLGEMAELGEDAIAEHDRIGRL 413 VTV++D+YNANPDSMRA L+AL +A EA RRSWAVLGEMAELG +++ EHD IGR Sbjct 356 VTVVNDSYNANPDSMRAALKALVSMARSGREAARRSWAVLGEMAELGPESVVEHDAIGRF 415 Query 414 AVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLR 473 AVRLDVSRL++VGTGR AMH GAV+EG+WG ++ V D A+ALL Sbjct 416 AVRLDVSRLIIVGTGRPARAMHQGAVMEGSWG-----------EESILVPDIAGAVALLE 464 Query 474 AELRPGDVVLVKASNAAGLGAVADALVADDT 504 EL PGD+VLVKAS + GL VAD ++A T Sbjct 465 KELAPGDLVLVKASQSIGLWEVADTVLAGST 495 >gi|289443662|ref|ZP_06433406.1| hypothetical protein TBLG_00764 [Mycobacterium tuberculosis T46] gi|289416581|gb|EFD13821.1| hypothetical protein TBLG_00764 [Mycobacterium tuberculosis T46] Length=258 Score = 505 bits (1300), Expect = 8e-141, Method: Compositional matrix adjust. Identities = 257/258 (99%), Positives = 258/258 (100%), Gaps = 0/258 (0%) Query 253 VAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVT 312 +AAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVT Sbjct 1 MAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVT 60 Query 313 NALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAG 372 NALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAG Sbjct 61 NALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAG 120 Query 373 LQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSIS 432 LQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSIS Sbjct 121 LQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSIS 180 Query 433 AMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGL 492 AMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGL Sbjct 181 AMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGL 240 Query 493 GAVADALVADDTCGSVRP 510 GAVADALVADDTCGSVRP Sbjct 241 GAVADALVADDTCGSVRP 258 >gi|54023730|ref|YP_117972.1| putative UDP-N-acetylmuramoylalanyl-D-glutamyl- 2,6-diaminopimelate-D-alanyl-D-alanine ligase [Nocardia farcinica IFM 10152] gi|54015238|dbj|BAD56608.1| putative UDP-N-acetylmuramoylalanyl-D-glutamyl- 2,6-diaminopimelate-D-alanyl-D-alanine ligase [Nocardia farcinica IFM 10152] Length=499 Score = 504 bits (1297), Expect = 2e-140, Method: Compositional matrix adjust. Identities = 325/502 (65%), Positives = 372/502 (75%), Gaps = 18/502 (3%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MIE+T+ +IA++VGG + D + RVTGT EFDSR IG G LFLALPG RADGHD+ Sbjct 1 MIEMTLREIADVVGGTLHDAPDPEV---RVTGTAEFDSRRIGSGDLFLALPGERADGHDY 57 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPP--VAAPNVLAGVLEHDNDGSGAAVLAALAKLAT 118 AA+AVAAGAA VLAARPVGVPA+VV P + P + L HD DGSGAAVLAALA LA Sbjct 58 AAAAVAAGAAAVLAARPVGVPAVVVEPRRCSVP-ATSMALAHDADGSGAAVLAALAALAR 116 Query 119 AVAAQL-VAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRA 177 A +L AGGLT++G+TGSSGKTSTKDL+AAVLAPLG VVAPPGSFNNELGHPWT LRA Sbjct 117 ASVERLSAAGGLTVVGVTGSSGKTSTKDLLAAVLAPLGPVVAPPGSFNNELGHPWTALRA 176 Query 178 TRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQA 237 T T +L+LEM+AR G+IAALAE+APP IGVVLNVGTAHLGEFGSRE IA+ K EL +A Sbjct 177 TADTRFLVLEMSARGVGHIAALAEVAPPRIGVVLNVGTAHLGEFGSREAIARAKGELVEA 236 Query 238 VPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDA 297 +P G +LNADDP VAAMA TAARVVRV D A V LDE AR FTLH Sbjct 237 LPADGLAILNADDPNVAAMAARTAARVVRVGLSGDADYRASEVRLDEQARATFTLHTPAG 296 Query 298 QAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTV 357 E+RLGV G+HQV NAL AAAVA ECGA + VAAAL+ A VS RM V T DGVTV Sbjct 297 STEIRLGVHGEHQVGNALAAAAVASECGADLATVAAALSGARAVSERRMDVRTTADGVTV 356 Query 358 IDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRL 417 ++D+YNANPDS+RA L+AL ++ E RRSWAVLGEMAELGE+++ EHD IGRLAVRL Sbjct 357 VNDSYNANPDSVRAALKALVTMSRAGERPRRSWAVLGEMAELGEESVLEHDGIGRLAVRL 416 Query 418 DVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELR 477 DV RLVVVGTGR AMH GAV+EG+WG +V V D DAA+ALL E+ Sbjct 417 DVDRLVVVGTGRPSRAMHQGAVMEGSWGE-----------ESVLVPDIDAAVALLDREVE 465 Query 478 PGDVVLVKASNAAGLGAVADAL 499 PGDVVLVKAS + GL VA+ L Sbjct 466 PGDVVLVKASKSVGLWEVAEHL 487 >gi|256379769|ref|YP_003103429.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanylligase [Actinosynnema mirum DSM 43827] gi|255924072|gb|ACU39583.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase [Actinosynnema mirum DSM 43827] Length=490 Score = 501 bits (1291), Expect = 9e-140, Method: Compositional matrix adjust. Identities = 300/504 (60%), Positives = 357/504 (71%), Gaps = 23/504 (4%) Query 1 MIELTVAQIAEIVGGAV--ADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGH 58 MI LT+A+IAEIVGG + D SP V VEFD+R + PGGLFLALPG R DGH Sbjct 1 MITLTLAEIAEIVGGRLHGTDGSPV------VKAGVEFDTRKLLPGGLFLALPGERVDGH 54 Query 59 DHAASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAG--VLEHDNDGSGAAVLAALAKL 116 D AA+AVAAGAA VLA R V P+++ PPVA + G VL D+DGSGAAVLAAL KL Sbjct 55 DFAAAAVAAGAAGVLAGREVPAPSVIAPPVAPADEHEGAYVLSGDSDGSGAAVLAALGKL 114 Query 117 ATAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLR 176 A V +L AGGLT++G+TGSSGKTSTKDL+A VL+P G +APPGSFNNELGHPWT LR Sbjct 115 ARHVTDRLTAGGLTVVGVTGSSGKTSTKDLIAQVLSPTGATIAPPGSFNNELGHPWTALR 174 Query 177 ATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQ 236 A T YL+LE++AR G+IA L +APP IG VLNVGTAHLGEFGSRE +A+TK EL + Sbjct 175 ADEDTGYLVLELSARGPGHIADLCAVAPPRIGAVLNVGTAHLGEFGSREGVARTKGELVE 234 Query 237 AVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHD 296 A+P G VLNADDP V AMA+ T A+VV V + V A + LDE ARP FTL Sbjct 235 ALPEDGVAVLNADDPLVLAMAERTKAKVVLVGEHSRAQVRAVDIVLDEQARPGFTLLTPH 294 Query 297 AQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVT 356 A V+L V G HQV NAL AAAVALE GA+ +QVA L +A P+S HRM+V R DGVT Sbjct 295 GSARVQLAVHGPHQVGNALTAAAVALELGATPQQVADRLGSAKPISAHRMEVVDRADGVT 354 Query 357 VIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVR 416 V++DAYNANP+S++A L++LA I+ RRSWAVLG MAELG D++ HD IGRLAVR Sbjct 355 VVNDAYNANPESVKAALKSLATISRSTTPARRSWAVLGPMAELGADSVRAHDEIGRLAVR 414 Query 417 LDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAEL 476 LDV+RLVV+G AMH GA LEG+WG ++ V D AA+ LLR E+ Sbjct 415 LDVNRLVVIGD--DARAMHQGAHLEGSWGE-----------ESILVPDVAAAIELLRDEV 461 Query 477 RPGDVVLVKASNAAGLGAVADALV 500 RPGDVVLVKASN+ GL VA+AL+ Sbjct 462 RPGDVVLVKASNSYGLWRVAEALL 485 >gi|333918994|ref|YP_004492575.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Amycolicicoccus subflavus DQS3-9A1] gi|333481215|gb|AEF39775.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Amycolicicoccus subflavus DQS3-9A1] Length=513 Score = 497 bits (1280), Expect = 2e-138, Method: Compositional matrix adjust. Identities = 314/509 (62%), Positives = 375/509 (74%), Gaps = 22/509 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI +T+ ++A++ GG + D+ ++A VTGTVEFDSR + GGLFLALPGA+ADGHD+ Sbjct 1 MIAMTLREVADLTGGTLHDVPDENAV---VTGTVEFDSRKVTAGGLFLALPGAQADGHDY 57 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNV----LAGVLEHDNDGSGAAVLAALAKL 116 A +AV AGA +LAARPVGVPA+VVPP+AA + A LEHD DGSGAAVLAALAKL Sbjct 58 ARAAVDAGACAILAARPVGVPAVVVPPIAAQDSSWQGTAMALEHDADGSGAAVLAALAKL 117 Query 117 ATAVAAQLVAG-GLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVL 175 A A L GLT++G+TGS+GKTSTKDL+A+VL PLG +APPGSFNNE+GHPWT L Sbjct 118 ARANVDVLTEQHGLTVVGVTGSAGKTSTKDLIASVLKPLGSTIAPPGSFNNEIGHPWTAL 177 Query 176 RATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELP 235 RA T +L+LEM+AR G+IAALA APP IGVV+NVGTAHLGEFGSREVIA TK EL Sbjct 178 RAGIGTQFLVLEMSARGPGHIAALAATAPPRIGVVINVGTAHLGEFGSREVIAATKGELV 237 Query 236 QAVPHS---GAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTL 292 +++P + G VLNADDP VAAMAK T ARVV + + V A V LD+ AR FTL Sbjct 238 ESLPDAAAGGVAVLNADDPLVAAMAKRTTARVVFIGQSGNAHVRATDVRLDDQARASFTL 297 Query 293 HAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRG 352 A EV L V G+HQVTNALCAAAVALECGA+V+QVAAAL A VS RM V+TR Sbjct 298 TAPQGVTEVTLAVHGEHQVTNALCAAAVALECGATVDQVAAALGEAKAVSARRMDVSTRS 357 Query 353 DGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGR 412 DGVTVI+D+YNANPDS++A L+AL +A + +RR WAVLGEMAELGE+++ EHD IGR Sbjct 358 DGVTVINDSYNANPDSVKAALKALVTMARSGKPSRRCWAVLGEMAELGENSVIEHDGIGR 417 Query 413 LAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALL 472 AVRL V RLVVVGTGR AMH GAV+EG+W D +V V D AA+A L Sbjct 418 QAVRLLVDRLVVVGTGRPSHAMHQGAVMEGSW-----------DNESVLVPDAAAAIAAL 466 Query 473 RAELRPGDVVLVKASNAAGLGAVADALVA 501 AE+ PGDVVLVKAS + GL VA+AL+A Sbjct 467 TAEVSPGDVVLVKASQSVGLWTVAEALLA 495 >gi|296140346|ref|YP_003647589.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanylligase [Tsukamurella paurometabola DSM 20162] gi|296028480|gb|ADG79250.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase [Tsukamurella paurometabola DSM 20162] Length=510 Score = 497 bits (1279), Expect = 2e-138, Method: Compositional matrix adjust. Identities = 293/507 (58%), Positives = 348/507 (69%), Gaps = 23/507 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MIELT+AQIA+IVGG + D+ A VTGTVEFDSR IG G LFLALPGAR DGHD Sbjct 1 MIELTLAQIADIVGGTLHDVPDPQAT---VTGTVEFDSREIGSGDLFLALPGARVDGHDF 57 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLATAV 120 AA+A+ GA VL ARPVGVPAIVVP + LE D DG+GAAVL AL LA Sbjct 58 AATAIEKGAVAVLGARPVGVPAIVVPVSGETDNRVMALESDTDGAGAAVLTALGDLAAYC 117 Query 121 AAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRATRR 180 L A GLT++G+TGS+GKTSTKDL+AAVL PLGE VAPPGSFNNE+GHPWT LRAT Sbjct 118 TKSLAADGLTVVGVTGSAGKTSTKDLIAAVLRPLGETVAPPGSFNNEIGHPWTALRATAS 177 Query 181 TDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAVPH 240 T +L+LEM+AR G+IAALA++APP IGV LNVGTAHLGEFGSRE IA+ K EL +A+P Sbjct 178 TKFLVLEMSARGEGHIAALAKLAPPRIGVELNVGTAHLGEFGSREAIARAKGELVEALPV 237 Query 241 SGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQAE 300 G VLNADD AVAAMA TAARVV V A V LD AR FTLH A Sbjct 238 DGVAVLNADDAAVAAMASRTAARVVFYGTAE-AQVRATDVVLDAHARAAFTLHTAGGTAP 296 Query 301 VRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDD 360 V L V G+HQV NAL +AAV LECGA+ QVA AL+ A S RM V T GVTV++D Sbjct 297 VALKVHGEHQVHNALASAAVGLECGATTAQVAEALSGAGAASPRRMDVFTTDGGVTVVND 356 Query 361 AYNANPDSMRAGLQALAWIAHQPEA--------TRRSWAVLGEMAELGEDAIAEHDRIGR 412 YNANPD+MRA L++L ++ EA RR++AVLGEM ELGE++I EHDR+GR Sbjct 357 TYNANPDAMRAALRSLVLMSEHDEAGERLPGRDRRRTFAVLGEMGELGEESILEHDRLGR 416 Query 413 LAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALL 472 VRLD++ + VG+ R++ A+ GAV+EG+WGS A+ V A+ L Sbjct 417 FLVRLDITSTICVGSSRAVHALWQGAVMEGSWGS-----------EAIRVDTRAEAVERL 465 Query 473 RAELRPGDVVLVKASNAAGLGAVADAL 499 RAELRPGD+VLVKAS + + VA++L Sbjct 466 RAELRPGDLVLVKASKSEKMWEVAESL 492 >gi|226307043|ref|YP_002767003.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase [Rhodococcus erythropolis PR4] gi|226186160|dbj|BAH34264.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase [Rhodococcus erythropolis PR4] Length=519 Score = 487 bits (1254), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 306/513 (60%), Positives = 366/513 (72%), Gaps = 27/513 (5%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI +T+++IAEIVGG + D+ D +VTGTVEFDSR GPGGLFLALPGAR DGHDH Sbjct 1 MIPMTLSRIAEIVGGTLHDV---DDPSTQVTGTVEFDSRKAGPGGLFLALPGARVDGHDH 57 Query 61 AASAVAAGAAVVLAARPVGVPAIVVP--PVAAPNVLAGVLEHDNDGSGAAVLAALAKLAT 118 A +AVAAGA VLAARPVGVPAIVVP P P+ + +LEHD DGSGAAVL AL LA Sbjct 58 AEAAVAAGAVAVLAARPVGVPAIVVPSVPNDGPSAVM-LLEHDTDGSGAAVLHALGLLAR 116 Query 119 AVAAQLVA------GGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPW 172 AV +L A GGLT++G+TGS+GKTSTKDL+AA+L GEVVAPPGSFNNELG PW Sbjct 117 AVVDELAAEGSASGGGLTLVGVTGSAGKTSTKDLIAALLRERGEVVAPPGSFNNELGLPW 176 Query 173 TVLRATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKA 232 TVLRA +T +L+LEM+AR G++ L +IAPP IGVVLNVGTAHLGEFGSRE IA K Sbjct 177 TVLRADEKTRFLVLEMSARGVGHVGELTKIAPPKIGVVLNVGTAHLGEFGSREAIAVAKG 236 Query 233 ELPQAVPHS---GAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPR 289 EL +A+P + G VLNADD VAAMA T AR+V V + DV A V +D+ AR Sbjct 237 ELVEALPSAADGGVAVLNADDRMVAAMASRTKARIVFVGQSEDCDVRATDVVVDDQARAS 296 Query 290 FTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVT 349 FTL+ A +RL V G+H V+NAL AAAVALE G +V +A L S RM+VT Sbjct 297 FTLNCSQGSARIRLAVHGEHHVSNALAAAAVALENGLAVADIARVLEGTKAASARRMEVT 356 Query 350 TRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEAT-RRSWAVLGEMAELGEDAIAEHD 408 R DGVTV++D+YNANPDSMRA L+AL +A RRSWAVLGEM ELG +++ EHD Sbjct 357 ERADGVTVVNDSYNANPDSMRAALKALVSMARSDRHFGRRSWAVLGEMGELGPESVVEHD 416 Query 409 RIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAA 468 IGRLAVRLDVS+L+VVGTGR+ AMH GAV+EG+WG +V V D AA Sbjct 417 AIGRLAVRLDVSKLIVVGTGRTSRAMHQGAVMEGSWGD-----------ESVVVPDAAAA 465 Query 469 LALLRAELRPGDVVLVKASNAAGLGAVADALVA 501 +A+L AEL PGD+VLVKAS + L VA+A++A Sbjct 466 IAILEAELEPGDLVLVKASKSVELWTVAEAILA 498 >gi|229490386|ref|ZP_04384227.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Rhodococcus erythropolis SK121] gi|229322676|gb|EEN88456.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Rhodococcus erythropolis SK121] Length=519 Score = 486 bits (1251), Expect = 4e-135, Method: Compositional matrix adjust. Identities = 304/513 (60%), Positives = 366/513 (72%), Gaps = 27/513 (5%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI +T+++IAEIVGG + D+ D + +VTGTVEFDSR + PGGLFLALPGAR DGHDH Sbjct 1 MIPMTLSRIAEIVGGTLHDV---DDSSTQVTGTVEFDSRKVAPGGLFLALPGARVDGHDH 57 Query 61 AASAVAAGAAVVLAARPVGVPAIVVP--PVAAPNVLAGVLEHDNDGSGAAVLAALAKLAT 118 A +AVAAGA VLAARPVGVPAIVVP P P+ + +LEHD DGSGAAVL AL LA Sbjct 58 AEAAVAAGAVAVLAARPVGVPAIVVPSVPNDGPSAVM-LLEHDTDGSGAAVLHALGLLAR 116 Query 119 AVAAQLVA------GGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPW 172 AV +L GGLT++G+TGS+GKTSTKDL+AA+L GEVVAPPGSFNNELG PW Sbjct 117 AVVDELATDGTPADGGLTLVGVTGSAGKTSTKDLIAALLRECGEVVAPPGSFNNELGLPW 176 Query 173 TVLRATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKA 232 TVLRA +T +L+LEM+AR G++ L +IAPP IGVVLNVGTAHLGEFGSRE IA K Sbjct 177 TVLRADEKTRFLVLEMSARGVGHVGELTKIAPPKIGVVLNVGTAHLGEFGSREAIAVAKG 236 Query 233 ELPQAVPHS---GAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPR 289 EL +A+P + G VLNADD VAAMA T AR+V V + DV A V +D+ AR Sbjct 237 ELVEALPSAADGGVAVLNADDRMVAAMASRTKARIVFVGQSEDCDVRATDVVVDDQARAS 296 Query 290 FTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVT 349 FTL+ A +RL V G+H V+NAL AAAVALE G +V +A L S RM+VT Sbjct 297 FTLNCSQGSARIRLAVHGEHHVSNALAAAAVALENGLAVADIARVLEGTKAASARRMEVT 356 Query 350 TRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEAT-RRSWAVLGEMAELGEDAIAEHD 408 R DGVTV++D+YNANPDSMRA L+AL +A RRSWAVLGEM ELG +++ EHD Sbjct 357 ERADGVTVVNDSYNANPDSMRAALKALVSMARSDRHFGRRSWAVLGEMGELGPESVVEHD 416 Query 409 RIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAA 468 IGRLAVRLDVS+L+VVGTGR+ AMH GAV+EG+WG +V V D AA Sbjct 417 AIGRLAVRLDVSKLIVVGTGRTSRAMHQGAVMEGSWGD-----------ESVVVPDAAAA 465 Query 469 LALLRAELRPGDVVLVKASNAAGLGAVADALVA 501 +A+L AEL PGD+VLVKAS + L VA+A++A Sbjct 466 IAILEAELEPGDLVLVKASKSVELWTVAEAILA 498 >gi|300788101|ref|YP_003768392.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase [Amycolatopsis mediterranei U32] gi|299797615|gb|ADJ47990.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase [Amycolatopsis mediterranei U32] gi|340529685|gb|AEK44890.1| UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanine ligase [Amycolatopsis mediterranei S699] Length=500 Score = 471 bits (1213), Expect = 1e-130, Method: Compositional matrix adjust. Identities = 288/502 (58%), Positives = 354/502 (71%), Gaps = 21/502 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI L++A+IA++VGG + P +VTGTVEFD+R + GGLF+ALPG + DGHD Sbjct 1 MIVLSLAEIADVVGGRLHRADPG----AQVTGTVEFDTRELTSGGLFVALPGEKVDGHDF 56 Query 61 AASAVAAGAAVVLAARPVGVPAIVVPPVAA--PNVLAGVLEHDNDGSGAAVLAALAKLAT 118 AA AV AGA VLAAR V PAIVVPP+AA + + L D DGSGAAVLAALAKLA Sbjct 57 AAQAVEAGAVAVLAAREVDAPAIVVPPLAAGEAHERSVALTGDKDGSGAAVLAALAKLAR 116 Query 119 AVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLRAT 178 V +L G LT++G+TGSSGKTSTKD++A +L PLG +APPGSFNNELGHPWT LRA Sbjct 117 YVVQRLAEGELTVVGVTGSSGKTSTKDVIAQLLEPLGPTIAPPGSFNNELGHPWTALRAG 176 Query 179 RRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQAV 238 T +L+LE++AR G+IA LA IAPP IGVVLNVG+AH+GEFGSRE IA+TK EL +A+ Sbjct 177 AETRHLVLELSARGPGHIAHLAAIAPPKIGVVLNVGSAHVGEFGSREGIAKTKGELVEAL 236 Query 239 PHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLHAHDAQ 298 P G VLN DDP VAAMA T ARVV V + V A ++LD+ AR F L + Sbjct 237 PEDGVAVLNLDDPLVAAMASRTKARVVFVGESPSAQVRAENITLDDEARASFRLITPAGE 296 Query 299 AEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGDGVTVI 358 A V+L + G+H V NAL AAAVALE GA+ E++A L+A S RM+V TR DGVT++ Sbjct 297 AGVKLPLHGEHHVGNALSAAAVALELGATPEEIATRLSALERRSARRMEVVTRPDGVTIL 356 Query 359 DDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRLAVRLD 418 +D++NANP+SMRAGL+ALA A E RRSWAVLG M ELG D++ HD IGRL VRL+ Sbjct 357 NDSFNANPESMRAGLKALA--AMTRETGRRSWAVLGVMGELGADSVTAHDEIGRLVVRLN 414 Query 419 VSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLRAELRP 478 +++LVV+G +AMH GA EG+WG E+T V D +AA ALL +LRP Sbjct 415 IAKLVVIGP--EAAAMHQGAHQEGSWGE-ESTL----------VPDVEAAAALLHDQLRP 461 Query 479 GDVVLVKASNAAGLGAVADALV 500 GDVVLVKAS AAGL VA+AL+ Sbjct 462 GDVVLVKASKAAGLWRVAEALL 483 >gi|302528473|ref|ZP_07280815.1| UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase [Streptomyces sp. AA4] gi|302437368|gb|EFL09184.1| UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase [Streptomyces sp. AA4] Length=479 Score = 470 bits (1210), Expect = 2e-130, Method: Compositional matrix adjust. Identities = 273/475 (58%), Positives = 339/475 (72%), Gaps = 18/475 (3%) Query 30 VTGTVEFDSRAIGPGGLFLALPGARADGHDHAASAVAAGAAVVLAARPVGVPAIVVPPVA 89 +TG+VEFD+R +GPGGLFLALPG R DGHD AA AV AGA VLAAR V PAIVVPP+ Sbjct 1 MTGSVEFDTRKLGPGGLFLALPGERVDGHDFAAKAVEAGAVGVLAAREVDAPAIVVPPLP 60 Query 90 APNVLAG--VLEHDNDGSGAAVLAALAKLATAVAAQLVAGGLTIIGITGSSGKTSTKDLM 147 +G L D DGSGAAVLAALAKLA V +L AGGLT+IG+TGSSGKTSTKD++ Sbjct 61 PGQANSGSVALTGDTDGSGAAVLAALAKLARHVVDRLAAGGLTVIGVTGSSGKTSTKDVI 120 Query 148 AAVLAPLGEVVAPPGSFNNELGHPWTVLRATRRTDYLILEMAARHHGNIAALAEIAPPSI 207 A ++ P+G VAPPGSFN+ELGHPWT LRA T +L+LEM+AR G+IAA AE PP I Sbjct 121 AQLIEPMGPTVAPPGSFNSELGHPWTALRADASTKFLVLEMSARGVGHIAAAAETTPPRI 180 Query 208 GVVLNVGTAHLGEFGSREVIAQTKAELPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRV 267 G VLNVG+AH+GEFGSRE IA+ K EL +A+P G VLN DDP VAAMA T AR+V V Sbjct 181 GAVLNVGSAHVGEFGSREGIAKAKGELVEALPEDGLAVLNLDDPLVAAMASRTKARIVGV 240 Query 268 SRDNTGDVWAGPVSLDELARPRFTLHAHDAQAEVRLGVCGDHQVTNALCAAAVALECGAS 327 + A +++D ARP F L + +A V L + G+H V NAL AAA+A E GA+ Sbjct 241 GESAGAQIRAADITVDAEARPSFRLITPEGEAPVTLPLHGEHHVGNALSAAAIARELGAT 300 Query 328 VEQVAAALTAAPPVSRHRMQVTTRGDGVTVIDDAYNANPDSMRAGLQALAWIAHQPEATR 387 E++A L++ S RM+VTTR DGVT+++D+YNANP+S+RAGL+ALA ++ + R Sbjct 301 TEEIAQRLSSLQRRSERRMEVTTRADGVTILNDSYNANPESVRAGLKALASMSR---SGR 357 Query 388 RSWAVLGEMAELGEDAIAEHDRIGRLAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSG 447 R+WAVLG M ELGED++ HD IGRL VRL++ +LVVV G+ +AMH GA EG+WG Sbjct 358 RAWAVLGVMGELGEDSVNAHDSIGRLVVRLNIEKLVVV--GQEAAAMHQGAFQEGSWG-- 413 Query 448 EATADHGADRTAVNVADGDAALALLRAELRPGDVVLVKASNAAGLGAVADALVAD 502 +V V D +AA+A+L +LRPGDVVLVKAS AAGL VA+AL+AD Sbjct 414 ---------EESVLVPDVEAAVAVLHDQLRPGDVVLVKASKAAGLWRVAEALLAD 459 >gi|319949798|ref|ZP_08023821.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase [Dietzia cinnamea P4] gi|319436538|gb|EFV91635.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase [Dietzia cinnamea P4] Length=500 Score = 470 bits (1210), Expect = 3e-130, Method: Compositional matrix adjust. Identities = 297/509 (59%), Positives = 345/509 (68%), Gaps = 23/509 (4%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHRRVTGTVEFDSRAIGPGGLFLALPGARADGHDH 60 MI+LT+ +IA IVGG + P A VTGTVEFDSR + PGGLFLALPG R DGHD Sbjct 1 MIDLTLGEIAGIVGGRLVGGDPSTA----VTGTVEFDSRRLTPGGLFLALPGERVDGHDF 56 Query 61 AASAVAAGAAVVLAARPV-GVPA--IVVPPVAAPNVLAGVLEHDNDGSGAAVLAALAKLA 117 A A+ AGAA L A V GV IVVP V A L D DGSGAAVL AL LA Sbjct 57 VARALDAGAAGALVAHEVDGVDGAQIVVPAVDRRETNAMALAADTDGSGAAVLTALGALA 116 Query 118 TAVAAQLVAG-GLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWTVLR 176 A +LVA GL ++G+TGSSGKTSTKDL+ AVL+ G VVAPPGSFNNE+GHPWT LR Sbjct 117 RASVDRLVADHGLVVVGVTGSSGKTSTKDLIGAVLSAAGTVVAPPGSFNNEIGHPWTALR 176 Query 177 ATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAELPQ 236 A TD+L+LE++AR GNI LA +APP IGVVLNVGTAHLGEFGSREVIA TK EL + Sbjct 177 ADEDTDFLVLELSARAPGNIRELAALAPPRIGVVLNVGTAHLGEFGSREVIAATKGELVE 236 Query 237 AVP---HSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLH 293 A+P H G VLNADD VAAMA T+A VV V + DV A V LD+ R FTL Sbjct 237 ALPDAAHGGVAVLNADDDRVAAMAGRTSAEVVTVGLGGSADVRAEGVRLDDEVRASFTLV 296 Query 294 AHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGD 353 +AEV L V G+HQV NAL AAAV L CG VE++AAAL A S RM V D Sbjct 297 TPRGEAEVALRVHGEHQVGNALSAAAVGLACGMDVERIAAALGTAEAASERRMDVRVTAD 356 Query 354 GVTVIDDAYNANPDSMRAGLQALAWIAHQPEAT-RRSWAVLGEMAELGEDAIAEHDRIGR 412 G+TVI+D+YNANPDSMRA L++LA +A RR+WAVLGEMAELGEDA+ EHD IGR Sbjct 357 GITVINDSYNANPDSMRAALKSLAVMARSGGGRPRRTWAVLGEMAELGEDAVIEHDLIGR 416 Query 413 LAVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALL 472 VRLDVS+LVVVG GR AM GA+ EG+WGS A+H VA + A+ +L Sbjct 417 FLVRLDVSQLVVVGLGRPQRAMFQGAIQEGSWGS---EAEH--------VATAEEAVEIL 465 Query 473 RAELRPGDVVLVKASNAAGLGAVADALVA 501 + L PGD+VLVKAS A GL +VA+ ++A Sbjct 466 DSRLEPGDIVLVKASAAVGLWSVAEHVLA 494 >gi|257056721|ref|YP_003134553.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Saccharomonospora viridis DSM 43017] gi|256586593|gb|ACU97726.1| UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Saccharomonospora viridis DSM 43017] Length=487 Score = 461 bits (1187), Expect = 1e-127, Method: Compositional matrix adjust. Identities = 301/510 (60%), Positives = 362/510 (71%), Gaps = 33/510 (6%) Query 1 MIELTVAQIAEIVGGAVADISPQDAAHR-----RVTGTVEFDSRAIGPGGLFLALPGARA 55 MIELT+A+IAE V G + HR RVTG+VEFDSR + GGLF+ALPG RA Sbjct 1 MIELTLAEIAEAVSGRL---------HRADGGERVTGSVEFDSRKVTDGGLFVALPGERA 51 Query 56 DGHDHAASAVAAGAAVVLAARPVGVPAIVVPPV--AAPNVLAGVLEHDNDGSGAAVLAAL 113 DGHD AASAVAAGAA VLAAR V PA++VPP+ + + L D DGSGAAVLAAL Sbjct 52 DGHDFAASAVAAGAAGVLAAREVDAPAVIVPPLPPGQAHERSVALAGDTDGSGAAVLAAL 111 Query 114 AKLATAVAAQLVAGGLTIIGITGSSGKTSTKDLMAAVLAPLGEVVAPPGSFNNELGHPWT 173 A LA V +L GLT++G+TGSSGKTSTKDL+A +L PLG VAPPGSFNNELGHPWT Sbjct 112 AALARHVVTRLSETGLTVVGVTGSSGKTSTKDLIAQLLEPLGPTVAPPGSFNNELGHPWT 171 Query 174 VLRATRRTDYLILEMAARHHGNIAALAEIAPPSIGVVLNVGTAHLGEFGSREVIAQTKAE 233 LRA R+T +L+LE++AR G+IA LA +APP IGVVLNVG+AH+GEFGS+E IA+TK E Sbjct 172 ALRADRKTRHLVLELSARGPGHIAELAAVAPPRIGVVLNVGSAHVGEFGSQEGIARTKGE 231 Query 234 LPQAVPHSGAVVLNADDPAVAAMAKLTAARVVRVSRDNTGDVWAGPVSLDELARPRFTLH 293 L +A+P G VLN DDP VA MA+ T+ARVV V DV A V LDE AR F L Sbjct 232 LVEALPAEGVAVLNVDDPFVAEMAQRTSARVVGVGESPKADVRAENVRLDEHARASFDLV 291 Query 294 AHDAQAEVRLGVCGDHQVTNALCAAAVALECGASVEQVAAALTAAPPVSRHRMQVTTRGD 353 A +AEVRL + G+H V NAL AAAVALE G + +VAA L+AA S RM+VTTR D Sbjct 292 AGGERAEVRLQLVGEHHVGNALAAAAVALELGMPLSEVAAGLSAATRRSERRMEVTTRSD 351 Query 354 GVTVIDDAYNANPDSMRAGLQALAWIAHQPEATRRSWAVLGEMAELGEDAIAEHDRIGRL 413 GVTV++D+YNANP+SMRA L+ LA + ++RRSWAVLG M+ELG D+++ HD IGRL Sbjct 352 GVTVLNDSYNANPESMRAALKTLASMT----SSRRSWAVLGVMSELGADSVSAHDEIGRL 407 Query 414 AVRLDVSRLVVVGTGRSISAMHHGAVLEGAWGSGEATADHGADRTAVNVADGDAALALLR 473 AVRL+++RLVVV G +AMH GA EG+WG +V V D DAA+ALLR Sbjct 408 AVRLNINRLVVV--GEQAAAMHRGASHEGSWGE-----------ESVLVPDTDAAVALLR 454 Query 474 AELRPGDVVLVKASNAAGLGAVADALVADD 503 +LRP DVVLVKAS A L VADAL+ +D Sbjct 455 EQLRPNDVVLVKASKVAELWRVADALLEED 484 Lambda K H 0.317 0.131 0.378 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1107811580136 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40