BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2158c Length=535 Score E Sequences producing significant alignments: (Bits) Value gi|15609295|ref|NP_216674.1| UDP-N-acetylmuramoylalanyl-D-glutam... 1029 0.0 gi|13881902|gb|AAK46501.1| UDP-N-acetylmuramoylalanyl-D-glutamat... 1027 0.0 gi|281306936|pdb|2WTZ|A Chain A, Mure Ligase Of Mycobacterium Tu... 1026 0.0 gi|289745330|ref|ZP_06504708.1| UDP-N-acetylmuramoylalanyl-D-glu... 1026 0.0 gi|340627166|ref|YP_004745618.1| putative UDP-N-acetylmuramoylal... 1025 0.0 gi|254232316|ref|ZP_04925643.1| UDP-N-acetylmuramoylalanyl-D-glu... 1004 0.0 gi|297634747|ref|ZP_06952527.1| UDP-N-acetylmuramoylalanyl-D-glu... 996 0.0 gi|306779455|ref|ZP_07417792.1| UDP-N-acetylmuramoylalanyl-D-glu... 829 0.0 gi|289762319|ref|ZP_06521697.1| UDP-N-acetylmuramyl tripeptide s... 762 0.0 gi|289758280|ref|ZP_06517658.1| UDP-N-acetylmuramoylalanyl-D-glu... 753 0.0 gi|240168222|ref|ZP_04746881.1| UDP-N-acetylmuramoylalanyl-D-glu... 740 0.0 gi|118618800|ref|YP_907132.1| UDP-N-acetylmuramoylalanyl-D-gluta... 739 0.0 gi|183983188|ref|YP_001851479.1| UDP-N-acetylmuramoylalanyl-D-gl... 735 0.0 gi|296166028|ref|ZP_06848478.1| UDP-N-acetylmuramoylalanyl-D-glu... 728 0.0 gi|289754268|ref|ZP_06513646.1| predicted protein [Mycobacterium... 724 0.0 gi|118462627|ref|YP_881535.1| UDP-N-acetylmuramoylalanyl-D-gluta... 723 0.0 gi|41408000|ref|NP_960836.1| UDP-N-acetylmuramoylalanyl-D-glutam... 722 0.0 gi|342859874|ref|ZP_08716527.1| UDP-N-acetylmuramoylalanyl-D-glu... 712 0.0 gi|254821906|ref|ZP_05226907.1| UDP-N-acetylmuramoylalanyl-D-glu... 703 0.0 gi|15827429|ref|NP_301692.1| UDP-N-acetylmuramoylalanyl-D-glutam... 702 0.0 gi|333990378|ref|YP_004522992.1| UDP-N-acetylmuramoylalanyl-D-gl... 680 0.0 gi|289447786|ref|ZP_06437530.1| UDP-N-acetylMuramoylalanyl-D-glu... 672 0.0 gi|108800227|ref|YP_640424.1| UDP-N-acetylmuramoylalanyl-D-gluta... 610 2e-172 gi|145223570|ref|YP_001134248.1| UDP-N-acetylmuramoylalanyl-D-gl... 594 1e-167 gi|126435850|ref|YP_001071541.1| UDP-N-acetylmuramoylalanyl-D-gl... 592 4e-167 gi|120404500|ref|YP_954329.1| UDP-N-acetylmuramoylalanyl-D-gluta... 572 8e-161 gi|118472293|ref|YP_888509.1| UDP-N-acetylmuramoylalanyl-D-gluta... 568 7e-160 gi|169629088|ref|YP_001702737.1| UDP-N-acetylmuramoylalanyl-D-gl... 553 3e-155 gi|289570275|ref|ZP_06450502.1| UDP-N-acetylmuramoylalanyl-D-glu... 525 8e-147 gi|333918993|ref|YP_004492574.1| UDP-N-acetylmuramoylalanyl-D-gl... 489 4e-136 gi|307084812|ref|ZP_07493925.1| putative Mur ligase family, glut... 486 3e-135 gi|289443663|ref|ZP_06433407.1| UDP-N-acetylMuramoylalanyl-D-glu... 484 2e-134 gi|226307044|ref|YP_002767004.1| UDP-N-acetylmuramoylalanyl-D-gl... 476 3e-132 gi|312140147|ref|YP_004007483.1| UDP-N-acetylmuramoyl-l-alanyl-d... 475 7e-132 gi|229490463|ref|ZP_04384304.1| UDP-N-acetylmuramoyl-L-alanyl-D-... 475 9e-132 gi|325676972|ref|ZP_08156644.1| UDP-N-acetylmuramoylalanyl-D-glu... 474 1e-131 gi|326382555|ref|ZP_08204246.1| UDP-N-acetylmuramoylalanyl-D-glu... 473 3e-131 gi|226360235|ref|YP_002778013.1| UDP-N-acetylmuramoylalanyl-D-gl... 471 1e-130 gi|343924205|ref|ZP_08763768.1| UDP-N-acetylmuramoyl-L-alanyl-D-... 455 9e-126 gi|324998161|ref|ZP_08119273.1| UDP-N-acetylmuramoylalanyl-D-glu... 454 1e-125 gi|111018106|ref|YP_701078.1| UDP-N-acetylmuramoylalanyl-D-gluta... 450 2e-124 gi|262202914|ref|YP_003274122.1| UDP-N-acetylmuramyl-tripeptide ... 445 7e-123 gi|331696615|ref|YP_004332854.1| UDP-N-acetylmuramoyl-L-alanyl-D... 445 9e-123 gi|296394969|ref|YP_003659853.1| UDP-N-acetylmuramyl-tripeptide ... 434 2e-119 gi|237785338|ref|YP_002906043.1| UDP-N-acetylmuramoylalanyl-D-gl... 434 2e-119 gi|54023729|ref|YP_117971.1| UDP-N-acetylmuramoylalanyl-D-glutam... 431 2e-118 gi|258654055|ref|YP_003203211.1| UDP-N-acetylmuramyl-tripeptide ... 430 4e-118 gi|302528474|ref|ZP_07280816.1| UDP-N-acetylmuramoylalanyl-D-glu... 428 1e-117 gi|296140347|ref|YP_003647590.1| UDP-N-acetylmuramyl-tripeptide ... 424 2e-116 gi|337291125|ref|YP_004630146.1| UDP-N-acetylmuramoylalanyl-D-gl... 422 9e-116 >gi|15609295|ref|NP_216674.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium tuberculosis H37Rv] gi|31793338|ref|NP_855831.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium bovis AF2122/97] gi|121638040|ref|YP_978264.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium bovis BCG str. Pasteur 1173P2] 30 more sequence titles Length=535 Score = 1029 bits (2660), Expect = 0.0, Method: Compositional matrix adjust. Identities = 534/535 (99%), Positives = 535/535 (100%), Gaps = 0/535 (0%) Query 1 VSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 +SSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR Sbjct 1 MSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 Query 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP Sbjct 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 Query 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT Sbjct 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 Query 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA Sbjct 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 Query 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS Sbjct 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 Query 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV 360 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV Sbjct 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV 360 Query 361 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA 420 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA Sbjct 361 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA 420 Query 421 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD 480 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD Sbjct 421 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD 480 Query 481 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 535 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA Sbjct 481 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 535 >gi|13881902|gb|AAK46501.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Mycobacterium tuberculosis CDC1551] Length=581 Score = 1027 bits (2656), Expect = 0.0, Method: Compositional matrix adjust. Identities = 535/535 (100%), Positives = 535/535 (100%), Gaps = 0/535 (0%) Query 1 VSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 VSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR Sbjct 47 VSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 106 Query 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP Sbjct 107 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 166 Query 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT Sbjct 167 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 226 Query 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA Sbjct 227 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 286 Query 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS Sbjct 287 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 346 Query 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV 360 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV Sbjct 347 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV 406 Query 361 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA 420 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA Sbjct 407 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA 466 Query 421 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD 480 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD Sbjct 467 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD 526 Query 481 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 535 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA Sbjct 527 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 581 >gi|281306936|pdb|2WTZ|A Chain A, Mure Ligase Of Mycobacterium Tuberculosis gi|281306937|pdb|2WTZ|B Chain B, Mure Ligase Of Mycobacterium Tuberculosis gi|281306938|pdb|2WTZ|C Chain C, Mure Ligase Of Mycobacterium Tuberculosis gi|281306939|pdb|2WTZ|D Chain D, Mure Ligase Of Mycobacterium Tuberculosis gi|303324784|pdb|2XJA|A Chain A, Structure Of Mure From M.Tuberculosis With Dipeptide And Adp gi|303324785|pdb|2XJA|B Chain B, Structure Of Mure From M.Tuberculosis With Dipeptide And Adp gi|303324786|pdb|2XJA|C Chain C, Structure Of Mure From M.Tuberculosis With Dipeptide And Adp gi|303324787|pdb|2XJA|D Chain D, Structure Of Mure From M.Tuberculosis With Dipeptide And Adp Length=535 Score = 1026 bits (2654), Expect = 0.0, Method: Compositional matrix adjust. Identities = 533/535 (99%), Positives = 534/535 (99%), Gaps = 0/535 (0%) Query 1 VSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 +SSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR Sbjct 1 MSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 Query 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP Sbjct 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 Query 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT Sbjct 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 Query 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA Sbjct 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 Query 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 FTNLSRDHLDFHPSMADYFEA ASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS Sbjct 241 FTNLSRDHLDFHPSMADYFEAXASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 Query 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV 360 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV Sbjct 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV 360 Query 361 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA 420 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA Sbjct 361 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA 420 Query 421 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD 480 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD Sbjct 421 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD 480 Query 481 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 535 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA Sbjct 481 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 535 >gi|289745330|ref|ZP_06504708.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Mycobacterium tuberculosis 02_1987] gi|289685858|gb|EFD53346.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Mycobacterium tuberculosis 02_1987] Length=535 Score = 1026 bits (2652), Expect = 0.0, Method: Compositional matrix adjust. Identities = 532/533 (99%), Positives = 533/533 (100%), Gaps = 0/533 (0%) Query 1 VSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 +SSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR Sbjct 1 MSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 Query 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP Sbjct 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 Query 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT Sbjct 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 Query 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA Sbjct 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 Query 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS Sbjct 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 Query 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV 360 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV Sbjct 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV 360 Query 361 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA 420 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA Sbjct 361 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA 420 Query 421 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD 480 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD Sbjct 421 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD 480 Query 481 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALER 533 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALER Sbjct 481 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALER 533 >gi|340627166|ref|YP_004745618.1| putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE [Mycobacterium canettii CIPT 140010059] gi|340005356|emb|CCC44514.1| putative UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE [Mycobacterium canettii CIPT 140010059] Length=535 Score = 1025 bits (2649), Expect = 0.0, Method: Compositional matrix adjust. Identities = 532/535 (99%), Positives = 533/535 (99%), Gaps = 0/535 (0%) Query 1 VSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 +SSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEG AQRAVTEDR Sbjct 1 MSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGTAQRAVTEDR 60 Query 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP Sbjct 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 Query 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT Sbjct 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 Query 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA Sbjct 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 Query 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS Sbjct 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 Query 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV 360 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV Sbjct 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGV 360 Query 361 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA 420 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA Sbjct 361 SPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGA 420 Query 421 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIAD 480 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGA EVGGDAQVVEIAD Sbjct 421 GGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAHEVGGDAQVVEIAD 480 Query 481 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 535 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA Sbjct 481 RRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 535 >gi|254232316|ref|ZP_04925643.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat E ligase murE [Mycobacterium tuberculosis C] gi|294993544|ref|ZP_06799235.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium tuberculosis 210] gi|297731736|ref|ZP_06960854.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium tuberculosis KZN R506] gi|313659071|ref|ZP_07815951.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium tuberculosis KZN V2475] gi|124601375|gb|EAY60385.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat E ligase murE [Mycobacterium tuberculosis C] gi|323719274|gb|EGB28417.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat E ligase murE [Mycobacterium tuberculosis CDC1551A] Length=521 Score = 1004 bits (2597), Expect = 0.0, Method: Compositional matrix adjust. Identities = 520/521 (99%), Positives = 521/521 (100%), Gaps = 0/521 (0%) Query 15 VATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSP 74 +ATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSP Sbjct 1 MATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSP 60 Query 75 GDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGL 134 GDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGL Sbjct 61 GDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGL 120 Query 135 AATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSAL 194 AATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSAL Sbjct 121 AATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSAL 180 Query 195 TTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPS 254 TTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPS Sbjct 181 TTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPS 240 Query 255 MADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVA 314 MADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVA Sbjct 241 MADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVA 300 Query 315 PTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRV 374 PTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRV Sbjct 301 PTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRV 360 Query 375 PGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGR 434 PGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGR Sbjct 361 PGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGR 420 Query 435 IAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARP 494 IAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARP Sbjct 421 IAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARP 480 Query 495 GDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 535 GDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA Sbjct 481 GDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 521 >gi|297634747|ref|ZP_06952527.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium tuberculosis KZN 4207] gi|306776408|ref|ZP_07414745.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat E ligase MurE [Mycobacterium tuberculosis SUMu001] gi|306789299|ref|ZP_07427621.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat E ligase MurE [Mycobacterium tuberculosis SUMu004] 12 more sequence titles Length=517 Score = 996 bits (2574), Expect = 0.0, Method: Compositional matrix adjust. Identities = 516/517 (99%), Positives = 517/517 (100%), Gaps = 0/517 (0%) Query 19 VEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLF 78 +EAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLF Sbjct 1 MEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLF 60 Query 79 AALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATV 138 AALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATV Sbjct 61 AALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATV 120 Query 139 YGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPE 198 YGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPE Sbjct 121 YGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPE 180 Query 199 APTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADY 258 APTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADY Sbjct 181 APTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADY 240 Query 259 FEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDA 318 FEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDA Sbjct 241 FEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDA 300 Query 319 GGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRL 378 GGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRL Sbjct 301 GGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRL 360 Query 379 EQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQ 438 EQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQ Sbjct 361 EQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQ 420 Query 439 LADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVV 498 LADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVV Sbjct 421 LADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVV 480 Query 499 LIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 535 LIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA Sbjct 481 LIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 517 >gi|306779455|ref|ZP_07417792.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat E ligase MurE [Mycobacterium tuberculosis SUMu002] gi|308327593|gb|EFP16444.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelat E ligase MurE [Mycobacterium tuberculosis SUMu002] Length=425 Score = 829 bits (2142), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/425 (100%), Positives = 425/425 (100%), Gaps = 0/425 (0%) Query 111 AEIAGRAAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRA 170 AEIAGRAAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRA Sbjct 1 AEIAGRAAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRA 60 Query 171 AGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGR 230 AGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGR Sbjct 61 AGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGR 120 Query 231 VDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMA 290 VDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMA Sbjct 121 VDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMA 180 Query 291 ARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLV 350 ARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLV Sbjct 181 ARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLV 240 Query 351 ALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHP 410 ALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHP Sbjct 241 ALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHP 300 Query 411 DRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVG 470 DRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVG Sbjct 301 DRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVG 360 Query 471 GDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEA 530 GDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEA Sbjct 361 GDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEA 420 Query 531 LERRA 535 LERRA Sbjct 421 LERRA 425 >gi|289762319|ref|ZP_06521697.1| UDP-N-acetylmuramyl tripeptide synthase [Mycobacterium tuberculosis GM 1503] gi|289709825|gb|EFD73841.1| UDP-N-acetylmuramyl tripeptide synthase [Mycobacterium tuberculosis GM 1503] Length=390 Score = 762 bits (1968), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/390 (99%), Positives = 390/390 (100%), Gaps = 0/390 (0%) Query 146 LTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAM 205 +TVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAM Sbjct 1 MTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAM 60 Query 206 LAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASL 265 LAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASL Sbjct 61 LAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASL 120 Query 266 FDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTA 325 FDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTA Sbjct 121 FDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTA 180 Query 326 IDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQ 385 IDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQ Sbjct 181 IDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQ 240 Query 386 GFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVV 445 GFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVV Sbjct 241 GFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVV 300 Query 446 TDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGH 505 TDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGH Sbjct 301 TDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGH 360 Query 506 ETGQRGGGRVRPFDDRVELAAALEALERRA 535 ETGQRGGGRVRPFDDRVELAAALEALERRA Sbjct 361 ETGQRGGGRVRPFDDRVELAAALEALERRA 390 >gi|289758280|ref|ZP_06517658.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE [Mycobacterium tuberculosis T85] gi|289713844|gb|EFD77856.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE [Mycobacterium tuberculosis T85] Length=417 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/392 (99%), Positives = 391/392 (99%), Gaps = 0/392 (0%) Query 19 VEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLF 78 +EAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLF Sbjct 1 MEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLF 60 Query 79 AALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATV 138 AALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATV Sbjct 61 AALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATV 120 Query 139 YGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPE 198 YGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPE Sbjct 121 YGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPE 180 Query 199 APTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADY 258 APTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADY Sbjct 181 APTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADY 240 Query 259 FEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDA 318 FEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDA Sbjct 241 FEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDA 300 Query 319 GGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRL 378 GGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRL Sbjct 301 GGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRL 360 Query 379 EQIDRGQGFLALVDYAHKPEALRSVLTTLAHP 410 EQIDRGQGFLALVDYAHKPEALRSVLTTL+ P Sbjct 361 EQIDRGQGFLALVDYAHKPEALRSVLTTLSAP 392 >gi|240168222|ref|ZP_04746881.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium kansasii ATCC 12478] Length=528 Score = 740 bits (1910), Expect = 0.0, Method: Compositional matrix adjust. Identities = 412/513 (81%), Positives = 438/513 (86%), Gaps = 3/513 (0%) Query 20 EAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVT-EDRTVTGVTLRAQDVSPGDLF 78 E+ P GLRP V GV+LA LA Q GA + +G A T D +TGVTLRAQDV PGDLF Sbjct 3 ESMPNGLRPRTVAGVKLAVLAAQTGA-VPDGAADYPETFRDVQITGVTLRAQDVQPGDLF 61 Query 79 AALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLAAT 137 AAL GS THGARH G+AI RGAVAVLTD GVA + AA VPVLVHPAPR VLGGLAAT Sbjct 62 AALAGSATHGARHAGEAIERGAVAVLTDADGVAAMGAHAASVPVLVHPAPRSVLGGLAAT 121 Query 138 VYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTP 197 VYG PSERLTV+GITGTSGKTTTTYLVEAGLRA GRVAGLIGTIGIR+ GAD+PSALTTP Sbjct 122 VYGRPSERLTVVGITGTSGKTTTTYLVEAGLRAGGRVAGLIGTIGIRIDGADIPSALTTP 181 Query 198 EAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMAD 257 EAP LQAMLA M ERGVDTVVMEVSSHALALGRVDGTRFAVG FTNLSRDHLDFHP+M D Sbjct 182 EAPALQAMLAEMSERGVDTVVMEVSSHALALGRVDGTRFAVGGFTNLSRDHLDFHPTMED 241 Query 258 YFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTD 317 YFEAKA LFDP SALRA T VVC+DDDAGRAMA RA DAITVSA DR AHWRA DV P Sbjct 242 YFEAKALLFDPASALRAGTVVVCVDDDAGRAMAERAGDAITVSARDRAAHWRAVDVVPMG 301 Query 318 AGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGR 377 A GQ+FTAIDPAGV H + I LPG YNVANCL+ALAILD++GVSPEQA PGLR+ RVPGR Sbjct 302 AAGQEFTAIDPAGVQHRVRIGLPGGYNVANCLLALAILDSIGVSPEQAAPGLRQARVPGR 361 Query 378 LEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAA 437 LEQ+DRGQ FLALVDYAHKP ALR+VLTTL PDRRLAVVFGAGG+RDPGKRAPMG +AA Sbjct 362 LEQVDRGQDFLALVDYAHKPGALRAVLTTLTSPDRRLAVVFGAGGERDPGKRAPMGAVAA 421 Query 438 QLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDV 497 +LADLVVVTDDNPR EDP AIRREILAGAA GG A+VVE+ADRRDAIRHAVAWA PGDV Sbjct 422 ELADLVVVTDDNPRGEDPAAIRREILAGAAAAGGTAEVVEVADRRDAIRHAVAWAGPGDV 481 Query 498 VLIAGKGHETGQRGGGRVRPFDDRVELAAALEA 530 VL+AGKGHETGQRG G VRPFDDRVELA AL A Sbjct 482 VLVAGKGHETGQRGAGEVRPFDDRVELAEALAA 514 >gi|118618800|ref|YP_907132.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium ulcerans Agy99] gi|118570910|gb|ABL05661.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase MurE [Mycobacterium ulcerans Agy99] Length=559 Score = 739 bits (1909), Expect = 0.0, Method: Compositional matrix adjust. Identities = 416/526 (80%), Positives = 445/526 (85%), Gaps = 7/526 (1%) Query 11 RRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQ 70 RRTEV ++VE+ LRP+A GV LA LA QVGA LA+GP + A D +TG+TLRAQ Sbjct 34 RRTEVVSEVESV---LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQ 90 Query 71 DVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP----VLVHPA 126 V PGDLFAAL GS THGARH DAI RGAVAVLTDPAGV I+ VP VLVHPA Sbjct 91 AVQPGDLFAALAGSATHGARHTADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPA 150 Query 127 PRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVG 186 PRGVLG AA VYGHPS+RLTV+GITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIR+ Sbjct 151 PRGVLGEAAALVYGHPSDRLTVVGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRID 210 Query 187 GADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSR 246 GAD+PS LTTPEAPTLQAMLAAMVERGVDTVVMEVSSHAL LGRVDG RFAVG FTNLSR Sbjct 211 GADIPSTLTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSR 270 Query 247 DHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPA 306 DHLDFHP+MADYFEAKA LFDP SALR + VVCIDD+AGRAMA RA AITVSA +PA Sbjct 271 DHLDFHPTMADYFEAKALLFDPASALRGHSVVVCIDDEAGRAMADRAGVAITVSATGQPA 330 Query 307 HWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAV 366 HWRATDVAP AGGQ+FTA+DPAGVGH + I PG YNV+NCL+ALAILD VGVSPEQA Sbjct 331 HWRATDVAPVGAGGQEFTALDPAGVGHRVRIGSPGHYNVSNCLLALAILDAVGVSPEQAA 390 Query 367 PGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDP 426 PGLRE RVPGRLEQ+DRGQ FLALVDYAHKP ALR VL+TL +P RRLAVVFGAGGDRDP Sbjct 391 PGLRETRVPGRLEQVDRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDP 450 Query 427 GKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIR 486 GKR PMGRIAA+LADLVVVTDDNPR EDP AIRR I+AGAAE GG AQVVEIADR +AI Sbjct 451 GKRGPMGRIAAELADLVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIG 510 Query 487 HAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALE 532 +AV WAR GDVVLIAGKGHETGQRGG VRPFDDRVELA ALEALE Sbjct 511 YAVDWARTGDVVLIAGKGHETGQRGGAEVRPFDDRVELARALEALE 556 >gi|183983188|ref|YP_001851479.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase MurE [Mycobacterium marinum M] gi|183176514|gb|ACC41624.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase MurE [Mycobacterium marinum M] Length=521 Score = 735 bits (1897), Expect = 0.0, Method: Compositional matrix adjust. Identities = 410/511 (81%), Positives = 435/511 (86%), Gaps = 4/511 (0%) Query 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 LRP+A GV LA LA QVGA LA+GP + A D +TG+TLRAQ V PGDLFAAL GS Sbjct 8 LRPSAGPGVPLAELAVQVGAVLADGPHRAAAVPDTLITGMTLRAQAVQPGDLFAALAGSA 67 Query 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP----VLVHPAPRGVLGGLAATVYGH 141 THGARH DAI RGAVAVLTDPAGV I+ VP VLVHPAPRGVLG AA VYGH Sbjct 68 THGARHAADAIERGAVAVLTDPAGVTAISALGCVPGTVPVLVHPAPRGVLGEAAALVYGH 127 Query 142 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 201 PS+RLTV+GITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIR+ GAD+PS LTTPEAP Sbjct 128 PSDRLTVVGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRIDGADIPSTLTTPEAPA 187 Query 202 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 261 LQAMLAAMVERGVDTVVMEVSSHAL LGRVDG RFAVG FTNLSRDHLDFHP+MADYFEA Sbjct 188 LQAMLAAMVERGVDTVVMEVSSHALTLGRVDGIRFAVGGFTNLSRDHLDFHPTMADYFEA 247 Query 262 KASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQ 321 KA LFDP SALR + VVCIDD+AGRAMA RA AITVSA +PAHWRATDVAP AGGQ Sbjct 248 KALLFDPASALRGHSVVVCIDDEAGRAMADRAGAAITVSATGQPAHWRATDVAPVGAGGQ 307 Query 322 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 381 +FTA+DPAGVGH + I LPG YNVANCL+ALAILD VGVSPEQA PGLRE RVPGRLEQ+ Sbjct 308 EFTALDPAGVGHRVRIGLPGHYNVANCLLALAILDAVGVSPEQAAPGLRETRVPGRLEQV 367 Query 382 DRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLAD 441 DRGQ FLALVDYAHKP ALR VL+TL +P RRLAVVFGAGGDRDPGKR PMGRIAA+LAD Sbjct 368 DRGQDFLALVDYAHKPGALREVLSTLRNPQRRLAVVFGAGGDRDPGKRGPMGRIAAELAD 427 Query 442 LVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIA 501 LVVVTDDNPR EDP AIRR I+AGAAE GG AQVVEIADR +AI +AV WAR GDVVLIA Sbjct 428 LVVVTDDNPRGEDPGAIRRTIVAGAAESGGAAQVVEIADRGEAIGYAVDWARTGDVVLIA 487 Query 502 GKGHETGQRGGGRVRPFDDRVELAAALEALE 532 GKGHETGQRGG VRPFDDRVELA ALEALE Sbjct 488 GKGHETGQRGGAEVRPFDDRVELARALEALE 518 >gi|296166028|ref|ZP_06848478.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898618|gb|EFG78174.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=516 Score = 728 bits (1878), Expect = 0.0, Method: Compositional matrix adjust. Identities = 408/513 (80%), Positives = 437/513 (86%), Gaps = 8/513 (1%) Query 23 PTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALT 82 PTGLRP+A G L ALA QVGA LA+ + A D VTGVTLRAQDV PGDLFAAL Sbjct 2 PTGLRPSAGAGTALPALAAQVGAVLAD---RAAAVPDVAVTGVTLRAQDVRPGDLFAALP 58 Query 83 GSTTHGARHVGDAIARGAVAVLTDPAGVAEI-AGRAAVPVLVHPAPRGVLGGLAATVYGH 141 GS+THGAR+ +AI RGAVAVLTD AGVAE+ A +AVP LVHPAPRGVLG LAATVYG+ Sbjct 59 GSSTHGARYAAEAIERGAVAVLTDAAGVAEMGASASAVPTLVHPAPRGVLGALAATVYGN 118 Query 142 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 201 PSER TVIGITGTSGKTTTTYLVEAGLRAAGR AGLIGT+GIR+ GAD+PSALTTPEAP Sbjct 119 PSERTTVIGITGTSGKTTTTYLVEAGLRAAGRTAGLIGTVGIRIDGADVPSALTTPEAPA 178 Query 202 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 261 LQA+ AAM ERGVDTVVMEVSSHALALGRVDGT FAVGAFTNLSRDHLDFHP+MADYFEA Sbjct 179 LQALFAAMAERGVDTVVMEVSSHALALGRVDGTGFAVGAFTNLSRDHLDFHPTMADYFEA 238 Query 262 KASLFDPDSALRARTAVVCIDDDAGRAMAARA----ADAITVSAADRPAHWRATDVAPTD 317 KA LFDP S LRAR VVC+DD+AGRAMA RA A AITVSAAD+PAHWRA DV P Sbjct 239 KAKLFDPASPLRARRVVVCVDDEAGRAMAMRAMQGGAAAITVSAADQPAHWRAMDVIPLG 298 Query 318 AGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGR 377 GGQQFTAIDPAGV H +GIRLPG YNVANCLVALAILD VGVSPEQA PGL + RVPGR Sbjct 299 TGGQQFTAIDPAGVRHRVGIRLPGHYNVANCLVALAILDAVGVSPEQAAPGLLDTRVPGR 358 Query 378 LEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAA 437 +E+ID GQ FLALVDYAHKP ALR+VLT+LA P RRLAVVFGAGG+RDPGKRAPMG AA Sbjct 359 MEEIDCGQDFLALVDYAHKPGALRAVLTSLARPGRRLAVVFGAGGERDPGKRAPMGATAA 418 Query 438 QLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDV 497 +LADLVVVTDDNPR EDP AIRREILAGAA GG A+VVEI DRR AI HAVAWARPGDV Sbjct 419 ELADLVVVTDDNPRGEDPAAIRREILAGAAAGGGAAEVVEIGDRRAAIEHAVAWARPGDV 478 Query 498 VLIAGKGHETGQRGGGRVRPFDDRVELAAALEA 530 VL+AGKGHETGQR G VRPFDDR+ELA AL+A Sbjct 479 VLVAGKGHETGQRAAGEVRPFDDRLELADALKA 511 >gi|289754268|ref|ZP_06513646.1| predicted protein [Mycobacterium tuberculosis EAS054] gi|289694855|gb|EFD62284.1| predicted protein [Mycobacterium tuberculosis EAS054] Length=373 Score = 724 bits (1868), Expect = 0.0, Method: Compositional matrix adjust. Identities = 370/373 (99%), Positives = 371/373 (99%), Gaps = 0/373 (0%) Query 163 LVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVS 222 +VE GLRAAGRVAGLIGTIG RVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVS Sbjct 1 MVEGGLRAAGRVAGLIGTIGNRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVS 60 Query 223 SHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCID 282 SHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCID Sbjct 61 SHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCID 120 Query 283 DDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGR 342 DDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGR Sbjct 121 DDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGR 180 Query 343 YNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRS 402 YNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRS Sbjct 181 YNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRS 240 Query 403 VLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREI 462 VLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREI Sbjct 241 VLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREI 300 Query 463 LAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRV 522 LAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRV Sbjct 301 LAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRV 360 Query 523 ELAAALEALERRA 535 ELAAALEALERRA Sbjct 361 ELAAALEALERRA 373 >gi|118462627|ref|YP_881535.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium avium 104] gi|254775003|ref|ZP_05216519.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium avium subsp. avium ATCC 25291] gi|167017295|sp|A0QF47.1|MURE_MYCA1 RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=UDP-MurNAc-tripeptide synthetase; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase gi|118163914|gb|ABK64811.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium avium 104] Length=520 Score = 723 bits (1865), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/506 (80%), Positives = 432/506 (86%), Gaps = 1/506 (0%) Query 23 PTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALT 82 PTGLRP+AV GVRL ALADQVGA +A GP +RA D TVTGVTLRAQDV PGDLFAAL Sbjct 5 PTGLRPSAVPGVRLPALADQVGAVMA-GPDRRAAVPDVTVTGVTLRAQDVLPGDLFAALP 63 Query 83 GSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATVYGHP 142 G+TTHGARH +AI RGAVAVLTD AGVA++ G P L+HP PR VLG LAA VY HP Sbjct 64 GATTHGARHAAEAIERGAVAVLTDAAGVAQLTGGRTTPTLLHPRPRSVLGELAAAVYAHP 123 Query 143 SERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTL 202 SERLTVIGITGTSGKTTTTYLVE+GLRAAGR AGLIGT+GIR+ GAD+PSALTTPEAP L Sbjct 124 SERLTVIGITGTSGKTTTTYLVESGLRAAGRTAGLIGTVGIRIDGADIPSALTTPEAPAL 183 Query 203 QAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAK 262 QA+LAAM E+ VDTVVMEVSSHALALGRVDGTRFAVG FTNLSRDHLDFHP+MADYFEAK Sbjct 184 QALLAAMAEQRVDTVVMEVSSHALALGRVDGTRFAVGGFTNLSRDHLDFHPTMADYFEAK 243 Query 263 ASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQ 322 A LFDP+S LRA AVVCIDD+AGR MAARA DA+TVSA +PAHWRA +VAP GGQQ Sbjct 244 ALLFDPNSPLRAHRAVVCIDDEAGREMAARAGDAVTVSAEGQPAHWRAVEVAPLGTGGQQ 303 Query 323 FTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQID 382 FT IDPAGV H GIRLPG YNVANCLVALA+LD VGVSPEQA PGL + RVPGR+E+ID Sbjct 304 FTVIDPAGVQHRAGIRLPGHYNVANCLVALALLDAVGVSPEQAAPGLLQTRVPGRMEEID 363 Query 383 RGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADL 442 GQ FLALVDYAHKP ALR+VL++L PDRRLAVVFGAGG+RDPGKRAPMG AA+LADL Sbjct 364 AGQDFLALVDYAHKPGALRAVLSSLKRPDRRLAVVFGAGGERDPGKRAPMGATAAELADL 423 Query 443 VVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAG 502 VVVTDDNPR EDP AIRREILAGA E G A+V+EI DRR AIRHAVAWA PGDVVL+AG Sbjct 424 VVVTDDNPRGEDPAAIRREILAGATESGCAAEVIEIGDRRAAIRHAVAWAGPGDVVLVAG 483 Query 503 KGHETGQRGGGRVRPFDDRVELAAAL 528 KGHETGQR G RPFDDRVELA AL Sbjct 484 KGHETGQRTGEHTRPFDDRVELAEAL 509 >gi|41408000|ref|NP_960836.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium avium subsp. paratuberculosis K-10] gi|81414074|sp|Q73YQ3.1|MURE_MYCPA RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=UDP-MurNAc-tripeptide synthetase; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase gi|41396354|gb|AAS04219.1| MurE [Mycobacterium avium subsp. paratuberculosis K-10] gi|336461948|gb|EGO40800.1| UDP-N-acetylmuramyl-tripeptide synthetase [Mycobacterium avium subsp. paratuberculosis S397] Length=520 Score = 722 bits (1863), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/506 (80%), Positives = 431/506 (86%), Gaps = 1/506 (0%) Query 23 PTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALT 82 PTGLRP+AV GVRL ALADQVGA +A GP +RA D TVTGVTLRAQDV PGDLFAAL Sbjct 5 PTGLRPSAVPGVRLPALADQVGAVMA-GPDRRAAVPDVTVTGVTLRAQDVLPGDLFAALP 63 Query 83 GSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATVYGHP 142 G+TTHGARH +AI RGAVAVLTD AGVA++ G P L+HP PR VLG LAA VY HP Sbjct 64 GATTHGARHAAEAIERGAVAVLTDAAGVAQLTGGRTTPTLLHPRPRSVLGQLAAAVYAHP 123 Query 143 SERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTL 202 SERLTVIGITGTSGKTTTTYLVE+GLRAAGR AGLIGT+GIR+ GAD+PSALTTPEAP L Sbjct 124 SERLTVIGITGTSGKTTTTYLVESGLRAAGRTAGLIGTVGIRIDGADIPSALTTPEAPAL 183 Query 203 QAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAK 262 QA+LAAM E+ VDTVVMEVSSHALALGRVDGTRFAVG FTNLSRDHLDFHP+MADYFEAK Sbjct 184 QALLAAMAEQRVDTVVMEVSSHALALGRVDGTRFAVGGFTNLSRDHLDFHPTMADYFEAK 243 Query 263 ASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQ 322 A LFDP+S LRA AVVCIDD+AGR MAARA DA+TVSA +PAHWRA +VAP GGQQ Sbjct 244 ALLFDPNSPLRAHRAVVCIDDEAGREMAARAGDAVTVSAEGQPAHWRAVEVAPLGTGGQQ 303 Query 323 FTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQID 382 FT IDPAGV H GIRLPG YNVANCLVALA+LD VGVSPEQA PGL + RVPGR+E+ID Sbjct 304 FTVIDPAGVQHRAGIRLPGHYNVANCLVALALLDAVGVSPEQAAPGLLQTRVPGRMEEID 363 Query 383 RGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADL 442 GQ FLALVDYAHKP ALR+VL++L PDRRLAVVFGAGG+RDPGKRAPMG AA+LADL Sbjct 364 AGQDFLALVDYAHKPGALRAVLSSLKRPDRRLAVVFGAGGERDPGKRAPMGATAAELADL 423 Query 443 VVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAG 502 VVVTDDNPR EDP AIRREILAG E G A+VVEI DRR AIRHAVAWA PGDVVL+AG Sbjct 424 VVVTDDNPRGEDPAAIRREILAGVTESGCAAEVVEIGDRRAAIRHAVAWAGPGDVVLVAG 483 Query 503 KGHETGQRGGGRVRPFDDRVELAAAL 528 KGHETGQR G RPFDDRVELA AL Sbjct 484 KGHETGQRTGEHTRPFDDRVELAEAL 509 >gi|342859874|ref|ZP_08716527.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium colombiense CECT 3035] gi|342133006|gb|EGT86226.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium colombiense CECT 3035] Length=530 Score = 712 bits (1839), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/509 (80%), Positives = 433/509 (86%), Gaps = 2/509 (0%) Query 23 PTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALT 82 PTGLRP+A G RLAALA QVGA A P Q A D T+TGVTLRAQDV PGDLFAAL Sbjct 19 PTGLRPSAATGARLAALAGQVGAQPAGAPGQDAAVPDVTITGVTLRAQDVRPGDLFAALP 78 Query 83 GSTTHGARHVGDAIARGAVAVLTDPAGVAEIA--GRAAVPVLVHPAPRGVLGGLAATVYG 140 G TTHGAR+ DAI RGA AVLTDPAGVAE+A G VP LVHP PRGVLGGLAATVYG Sbjct 79 GLTTHGARYAADAIERGAAAVLTDPAGVAEMAAAGAPTVPTLVHPDPRGVLGGLAATVYG 138 Query 141 HPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAP 200 PSER+ VIGITGTSGKTTTTY+VE+GLRAAGR AGLIGTIGIR+ G D+PSALTTPEAP Sbjct 139 RPSERVAVIGITGTSGKTTTTYMVESGLRAAGRTAGLIGTIGIRIDGVDIPSALTTPEAP 198 Query 201 TLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFE 260 LQAMLAAM E+GVDTVVMEVSSHALALGRVDGT FAVG FTNLSRDHLDFHP+M DYF+ Sbjct 199 ALQAMLAAMAEQGVDTVVMEVSSHALALGRVDGTGFAVGGFTNLSRDHLDFHPTMEDYFD 258 Query 261 AKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGG 320 KA LF+P+S LRAR AVVCIDD+AGRAMAARA DAITVSA RPAHWRA DVAP AGG Sbjct 259 TKALLFEPNSPLRARRAVVCIDDEAGRAMAARAGDAITVSAEGRPAHWRAVDVAPMGAGG 318 Query 321 QQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQ 380 QQFT IDPAG HH+GI LPG YNVANCLVALA+LD VGVSPE+A PGLR+ RVPGR+EQ Sbjct 319 QQFTVIDPAGAQHHVGIPLPGHYNVANCLVALALLDAVGVSPERAAPGLRQTRVPGRMEQ 378 Query 381 IDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLA 440 ID GQ FLALVDYAHKP ALR+VLTTLA P RR+AVVFGAGG+RDPGKR PMG AA+LA Sbjct 379 IDAGQDFLALVDYAHKPGALRAVLTTLARPGRRVAVVFGAGGERDPGKRRPMGATAAELA 438 Query 441 DLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLI 500 DLVVVTDDNPR EDP +IRREILAGA E G A+VVEIADRRDAIRHAVAWA GDVVLI Sbjct 439 DLVVVTDDNPRGEDPASIRREILAGATESGCAAEVVEIADRRDAIRHAVAWAGAGDVVLI 498 Query 501 AGKGHETGQRGGGRVRPFDDRVELAAALE 529 AGKGHETGQR G VRPFDDRVELA ALE Sbjct 499 AGKGHETGQRTGDVVRPFDDRVELARALE 527 >gi|254821906|ref|ZP_05226907.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium intracellulare ATCC 13950] Length=514 Score = 703 bits (1815), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/511 (79%), Positives = 431/511 (85%), Gaps = 5/511 (0%) Query 23 PTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALT 82 P+ LRP+A GVRL ALA +GAA PA + VTGVTLRAQ+V PGDLFAAL Sbjct 4 PSALRPSAAAGVRLPALAADIGAA----PAGDRAVPNLPVTGVTLRAQEVRPGDLFAALP 59 Query 83 GSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRA-AVPVLVHPAPRGVLGGLAATVYGH 141 GSTTHGAR+ GDAI RGAVAVLTD GVAE+ +VPVLVHP PRGVLGGLAATVYG+ Sbjct 60 GSTTHGARYAGDAIERGAVAVLTDAGGVAEMGALGQSVPVLVHPDPRGVLGGLAATVYGN 119 Query 142 PSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPT 201 PSER+TV+G+TGTSGKTTTTYL+E+ LRAAG AGLIGTIGIR+ GAD+PSALTTPEAP Sbjct 120 PSERVTVVGVTGTSGKTTTTYLIESALRAAGHTAGLIGTIGIRIDGADIPSALTTPEAPA 179 Query 202 LQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEA 261 LQAMLAAM E+GVDTVVMEVSSHAL LGRVDGTRFAVG FTNLSRDHLDFHP+MADYFEA Sbjct 180 LQAMLAAMAEQGVDTVVMEVSSHALTLGRVDGTRFAVGGFTNLSRDHLDFHPTMADYFEA 239 Query 262 KASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQ 321 KA LFDP S LRAR VVC+DDDAGRAMAARA DAITVSA RPAHWRATDVAP A GQ Sbjct 240 KAMLFDPSSPLRARRVVVCVDDDAGRAMAARAGDAITVSAEGRPAHWRATDVAPMGAAGQ 299 Query 322 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 381 +FTAIDPAG H +G+RLPG YNVANCLVALAILD VGVSPEQA GL + RVPGR+E+I Sbjct 300 RFTAIDPAGARHQLGVRLPGHYNVANCLVALAILDAVGVSPEQASTGLLQARVPGRMEEI 359 Query 382 DRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLAD 441 D GQ FLALVDYAHKP ALR+VLTTLA PDRRLAVVFGAGG+RDPGKRAPMG AA+LAD Sbjct 360 DAGQDFLALVDYAHKPGALRAVLTTLARPDRRLAVVFGAGGERDPGKRAPMGATAAELAD 419 Query 442 LVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIA 501 LVVVTDDNPR EDP +IRREILAGA E G A +VEIADRRDAIRHAVAWA PGDVVLIA Sbjct 420 LVVVTDDNPRGEDPASIRREILAGATESGCAADIVEIADRRDAIRHAVAWAGPGDVVLIA 479 Query 502 GKGHETGQRGGGRVRPFDDRVELAAALEALE 532 GKGHETGQ GG RPFDDRVELA AL L Sbjct 480 GKGHETGQSAGGHTRPFDDRVELAQALRDLN 510 >gi|15827429|ref|NP_301692.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium leprae TN] gi|221229906|ref|YP_002503322.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium leprae Br4923] gi|6093448|sp|O69557.1|MURE_MYCLE RecName: Full=UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; AltName: Full=Meso-A2pm-adding enzyme; AltName: Full=Meso-diaminopimelate-adding enzyme; AltName: Full=UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase; AltName: Full=UDP-MurNAc-tripeptide synthetase; AltName: Full=UDP-N-acetylmuramyl-tripeptide synthetase gi|3080478|emb|CAA18673.1| udp-n-acetylmuramoylalanyl-d-glutamate --2,6-diaminopimelate ligase [Mycobacterium leprae] gi|13092979|emb|CAC31290.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopime ligase (meso-diaminopimelate-adding enzyme) [Mycobacterium leprae] gi|219933013|emb|CAR71004.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopime ligase (meso-diaminopimelate-adding enzyme) [Mycobacterium leprae Br4923] Length=530 Score = 702 bits (1812), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/519 (75%), Positives = 426/519 (83%), Gaps = 1/519 (0%) Query 17 TQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGD 76 T+V A P LRP+A GVRL L QVGA LA+GP Q A D VTGVTLRAQ+V GD Sbjct 2 TEVVAVPVRLRPSATAGVRLPELVAQVGAVLADGPGQAATVPDIPVTGVTLRAQEVLSGD 61 Query 77 LFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLA 135 LFAAL G++THGAR+ G A+ RGAVAVLTD AGVAE+ +A+ VP+L+HP PR VLGGLA Sbjct 62 LFAALAGASTHGARYAGVALERGAVAVLTDVAGVAELTAQASSVPILIHPEPRSVLGGLA 121 Query 136 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 195 A YGHPS R+TV+GITGTSGKTTTTY+VEAGLRA GRV GL+GTIGIR+ GAD+PS LT Sbjct 122 AAAYGHPSNRMTVVGITGTSGKTTTTYMVEAGLRAGGRVVGLVGTIGIRIDGADIPSFLT 181 Query 196 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 255 TPEAP LQAMLAAMVERGV+TVVMEVSSHAL+LGRV+GT+FAV FTNLSRDHLDFHP M Sbjct 182 TPEAPALQAMLAAMVERGVETVVMEVSSHALSLGRVEGTQFAVAGFTNLSRDHLDFHPDM 241 Query 256 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAP 315 +YFEAKA LFDP S LRART VVCIDDDAGRA AARA DAITVSA +PA WRATD+ Sbjct 242 EEYFEAKAVLFDPHSLLRARTVVVCIDDDAGRATAARAGDAITVSALGQPASWRATDIRS 301 Query 316 TDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVP 375 G Q+FTA+DPAGV H +GIRLPGRYNVANCLVALAILD VGVSPEQA G R+IR+P Sbjct 302 PGVGAQEFTAVDPAGVQHRVGIRLPGRYNVANCLVALAILDVVGVSPEQASLGFRDIRIP 361 Query 376 GRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDRRLAVVFGAGGDRDPGKRAPMGRI 435 GRLE+ID GQ FLALVDYAHKP AL SVLT L PD RLAVVFGAGG+RDPGKRAPMG I Sbjct 362 GRLERIDCGQDFLALVDYAHKPGALHSVLTALLQPDHRLAVVFGAGGERDPGKRAPMGEI 421 Query 436 AAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPG 495 AA+LADLVVVTDDNPR EDP AIRR+IL G GG AQVVEI DRR AI++AVAWA P Sbjct 422 AAELADLVVVTDDNPRGEDPAAIRRDILTGTVAAGGAAQVVEIGDRRAAIQYAVAWAGPD 481 Query 496 DVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALERR 534 DVVL+AGKGHETGQRG PFDDRVELA AL+ + R Sbjct 482 DVVLVAGKGHETGQRGAAETCPFDDRVELARALQVRDAR 520 >gi|333990378|ref|YP_004522992.1| UDP-N-acetylmuramoylalanyl-D-glutamate-26- diaminopimelate ligase MurE [Mycobacterium sp. JDM601] gi|333486346|gb|AEF35738.1| UDP-N-acetylmuramoylalanyl-D-glutamate-26- diaminopimelate ligase MurE [Mycobacterium sp. JDM601] Length=521 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/524 (72%), Positives = 408/524 (78%), Gaps = 14/524 (2%) Query 18 QVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDL 77 +V A +RP G L LAD+VGA A G V + +TG+TLRAQD PGDL Sbjct 2 EVIAVSAAMRPEVGTGTPLRVLADRVGAVSATG----GVVPELPITGLTLRAQDAQPGDL 57 Query 78 FAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRA---AVPVLVHPAPRGVLGGL 134 FAAL G+TT GAR V DA+ARGAVAVL+D G AEI A +PVLVHPAPR VLG + Sbjct 58 FAALPGATTRGARFVADAVARGAVAVLSDGDGAAEITSGAVAPGIPVLVHPAPRAVLGEV 117 Query 135 AATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSAL 194 AATVY HP ERLTVIG+TGTSGKTTT YLVEAGLRAAGR GLIGT+G+R+ G DLPSAL Sbjct 118 AATVYRHPCERLTVIGVTGTSGKTTTAYLVEAGLRAAGRTPGLIGTVGVRIDGVDLPSAL 177 Query 195 TTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPS 254 TTPEAP LQA+LA M +RGVDTVVMEVSSHALALGR DGTRFAVGAFTNLSRDHLDFHPS Sbjct 178 TTPEAPALQALLAVMAQRGVDTVVMEVSSHALALGRADGTRFAVGAFTNLSRDHLDFHPS 237 Query 255 MADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDV- 313 MADYFEAKA LFDP S L A AVVCIDD+AG AMAARA+ +TVS RPA W V Sbjct 238 MADYFEAKARLFDPASPLHAARAVVCIDDEAGEAMAARASAPVTVSVTGRPAGWGVEGVS 297 Query 314 APTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIR 373 A GG++F A+DPAGV H +GI LPG YNVANCLVALAILD VGVSPEQA PGLR+ R Sbjct 298 AAAGPGGREFVAVDPAGVHHPVGIGLPGDYNVANCLVALAILDVVGVSPEQAAPGLRDAR 357 Query 374 VPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDR----RLAVVFGAGGDRDPGKR 429 VPGR+E IDRGQ FLALVDYAHKP AL +VL TL R RLAVVFGAGGDRD GKR Sbjct 358 VPGRMEPIDRGQDFLALVDYAHKPGALAAVLQTLRQDLRETAGRLAVVFGAGGDRDHGKR 417 Query 430 APMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAV 489 APMGRIAA+ ADLVV+TDDNPR EDP IRR ILAGAA+ G A VVEI DRR AI HAV Sbjct 418 APMGRIAAETADLVVITDDNPRGEDPADIRRAILAGAAD--GSAAVVEIGDRRAAIEHAV 475 Query 490 AWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALER 533 WARPGDVVL+AGKGHETGQ GGR +PFDDR+ELA ALEA E+ Sbjct 476 RWARPGDVVLVAGKGHETGQTAGGRTQPFDDRIELAQALEAREQ 519 >gi|289447786|ref|ZP_06437530.1| UDP-N-acetylMuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis CPHL_A] gi|289420744|gb|EFD17945.1| UDP-N-acetylMuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase MurF [Mycobacterium tuberculosis CPHL_A] Length=404 Score = 672 bits (1733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/349 (99%), Positives = 349/349 (100%), Gaps = 0/349 (0%) Query 1 VSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 +SSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR Sbjct 1 MSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 Query 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP Sbjct 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 Query 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT Sbjct 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 Query 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA Sbjct 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 Query 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS Sbjct 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVS 300 Query 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCL 349 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCL Sbjct 301 AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCL 349 >gi|108800227|ref|YP_640424.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium sp. MCS] gi|119869355|ref|YP_939307.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium sp. KMS] gi|108770646|gb|ABG09368.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium sp. MCS] gi|119695444|gb|ABL92517.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium sp. KMS] Length=508 Score = 610 bits (1574), Expect = 2e-172, Method: Compositional matrix adjust. Identities = 360/510 (71%), Positives = 397/510 (78%), Gaps = 8/510 (1%) Query 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 LRP+ VG L ALA+QV A PA D VTGVTLR QD PGDLFAAL GS+ Sbjct 5 LRPSHPVGHALGALAEQVQAV----PAPGFPVPDIRVTGVTLRGQDALPGDLFAALPGSS 60 Query 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATVYGHPSER 145 HGAR V DA+A GAVAVLTD AG + VPVLVHP PR VLG +A+TVYGHPS+ Sbjct 61 AHGARFVADAVAAGAVAVLTDAAGAVMLGADPVVPVLVHPDPRAVLGAVASTVYGHPSQH 120 Query 146 LTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAM 205 L V+G+TGTSGKTTTTYLVEAGLRAAGRVAGLIGT+GIR+ G D PSALTTPEAP LQA+ Sbjct 121 LRVVGVTGTSGKTTTTYLVEAGLRAAGRVAGLIGTVGIRIDGRDQPSALTTPEAPDLQAL 180 Query 206 LAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASL 265 LA MVE+GVDTVVMEVSSHAL LGRVDG FA G FTNLSRDHLDFHP+M DYF+AKA L Sbjct 181 LAVMVEQGVDTVVMEVSSHALTLGRVDGVHFAAGGFTNLSRDHLDFHPTMEDYFDAKAGL 240 Query 266 FDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTA 325 FDP S RA AVVC+DDDAGRAMA RA A+TVSA+ RPA WRA DV +AG Q+F A Sbjct 241 FDPQSRTRAELAVVCVDDDAGRAMAIRAGRAVTVSASGRPADWRAEDVRAVEAGAQEFVA 300 Query 326 IDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQ 385 +DPAGV H + I LPG YNVANC++A A+LD V VSPEQA PGLR VPGRLE +DRGQ Sbjct 301 VDPAGVHHGLRIALPGHYNVANCVLAAALLDAVDVSPEQAAPGLRTATVPGRLEAVDRGQ 360 Query 386 GFLALVDYAHKPEALRSVLTTLAHPDR-RLAVVFGAGGDRDPGKRAPMGRIAAQLADLVV 444 FLALVDYAHKP ALR+VL TL + R+AVVFGAGG+RD GKR PMGR+AA+LADLVV Sbjct 361 DFLALVDYAHKPGALRAVLETLRGQGKGRIAVVFGAGGNRDAGKREPMGRVAAELADLVV 420 Query 445 VTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKG 504 VTDDNPRDEDP IR I+AGA GG A VVEI DRR+AI HAV WARPGDVVL+AGKG Sbjct 421 VTDDNPRDEDPATIRAAIMAGARAAGGGADVVEIGDRREAIAHAVRWARPGDVVLVAGKG 480 Query 505 HETGQRGGGRVRPFDDRVELAAALEALERR 534 HETGQ GR PFDDRVELA E LE+R Sbjct 481 HETGQTAAGRTHPFDDRVELA---ELLEKR 507 >gi|145223570|ref|YP_001134248.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium gilvum PYR-GCK] gi|315443917|ref|YP_004076796.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium sp. Spyr1] gi|145216056|gb|ABP45460.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium gilvum PYR-GCK] gi|315262220|gb|ADT98961.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium sp. Spyr1] Length=512 Score = 594 bits (1532), Expect = 1e-167, Method: Compositional matrix adjust. Identities = 345/510 (68%), Positives = 381/510 (75%), Gaps = 12/510 (2%) Query 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 LRP+ VG+ L ALAD V A PA D VTGVTLR Q GDLFAAL GS Sbjct 3 LRPSHPVGMPLGALADLVCAE----PADAGPVPDLQVTGVTLRGQHAQAGDLFAALPGSK 58 Query 86 THGARHVGDAIARGAVAVLTDPAGVAEIA--GRAAVPVLVHPAPRGVLGGLAATVYGHPS 143 HGAR+ DA+ RGAVAVLTD GV+EIA G AVP+LVHPAPR VLG +AA V+G PS Sbjct 59 AHGARYAADAVERGAVAVLTDADGVSEIAAHGGPAVPILVHPAPRSVLGEVAAAVFGRPS 118 Query 144 ERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQ 203 E L VIG+TGTSGKTTTTYLVEAGLR+AGRVAGLIGT+G+R+ G P LTTPEAP LQ Sbjct 119 EHLRVIGVTGTSGKTTTTYLVEAGLRSAGRVAGLIGTVGVRIDGRAQPGGLTTPEAPDLQ 178 Query 204 AMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKA 263 A+LAAM+E+GVDTVVMEVSSHAL LGRVDG FAVG FTNLSRDHLDFHP+M DYFEAKA Sbjct 179 ALLAAMLEQGVDTVVMEVSSHALTLGRVDGVSFAVGGFTNLSRDHLDFHPTMQDYFEAKA 238 Query 264 SLFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQF 323 L DP S A +V+C+DD+ GRAMAARA +TVS A W +V D G Q F Sbjct 239 RLVDPTSPTHAARSVICVDDEWGRAMAARADAPVTVSVTGD-ADWWVQEVRALDGGVQDF 297 Query 324 TAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDR 383 A+DPAGV H + I LPG YNVANCL+A+A+LD V VSPEQA PGLR+ VPGRLE +DR Sbjct 298 LAVDPAGVHHALEIGLPGGYNVANCLLAVALLDAVDVSPEQAAPGLRDATVPGRLEAVDR 357 Query 384 GQGFLALVDYAHKPEALRSVLTTL-AHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADL 442 GQ FLALVDYAHKP AL +VL TL RLAVVFGAGGDRD GKR PMGR+AA+LADL Sbjct 358 GQPFLALVDYAHKPGALAAVLQTLREQCAGRLAVVFGAGGDRDQGKREPMGRVAAELADL 417 Query 443 VVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAG 502 VVVTDDNPR EDP IR IL GA+ AQ VEI DRR AI HAV WAR GD+VLIAG Sbjct 418 VVVTDDNPRGEDPAVIRAAILRGAS----GAQTVEIGDRRAAIVHAVQWAREGDIVLIAG 473 Query 503 KGHETGQRGGGRVRPFDDRVELAAALEALE 532 KGHE GQ GR RPFDDR ELAAALE L+ Sbjct 474 KGHEAGQTSQGRTRPFDDRDELAAALETLQ 503 >gi|126435850|ref|YP_001071541.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium sp. JLS] gi|126235650|gb|ABN99050.1| UDP-N-acetylmuramyl-tripeptide synthetase [Mycobacterium sp. JLS] Length=508 Score = 592 bits (1527), Expect = 4e-167, Method: Compositional matrix adjust. Identities = 359/510 (71%), Positives = 395/510 (78%), Gaps = 8/510 (1%) Query 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 LRP+ VG L ALA+QV A PA D VTGVTLR QD PGDLFAAL GS+ Sbjct 5 LRPSHPVGHALGALAEQVQAV----PAPGFPVPDIRVTGVTLRGQDALPGDLFAALPGSS 60 Query 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATVYGHPSER 145 HGAR V DA+A GAVAVLTD AG + VPVLVHP PR VLG +A+TVYGHPS+ Sbjct 61 AHGARFVADAVAAGAVAVLTDAAGAVMLGADPVVPVLVHPDPRAVLGAVASTVYGHPSQH 120 Query 146 LTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAM 205 L V+G+TGTSGKTTTTYLVEAGLRAAGRVAGLIGT+GIR+ G D PSALTTPEAP LQA+ Sbjct 121 LRVVGVTGTSGKTTTTYLVEAGLRAAGRVAGLIGTVGIRIDGRDQPSALTTPEAPDLQAL 180 Query 206 LAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASL 265 LA MVE+GVDTVVMEVSSHAL LGRVDG FA G FTNLSRDHLDFHP+M DYF+AKA L Sbjct 181 LAVMVEQGVDTVVMEVSSHALTLGRVDGVHFAAGGFTNLSRDHLDFHPTMEDYFDAKAGL 240 Query 266 FDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTA 325 FDP S RA AVVC+DDDAGRAMA RA A+TVSA+ RPA WRA DV +AG Q+F A Sbjct 241 FDPQSRTRAELAVVCVDDDAGRAMAIRAGRAVTVSASGRPADWRAEDVRAVEAGAQEFVA 300 Query 326 IDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQ 385 +DPAGV H + I LPG YNVANCL+A A+LD V VSPEQA PGLR VPGRLE +DRGQ Sbjct 301 VDPAGVHHGLRIALPGHYNVANCLLAAALLDAVDVSPEQAAPGLRTATVPGRLEAVDRGQ 360 Query 386 GFLALVDYAHKPEALRSVLTTL-AHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVV 444 FLALVDYAHKP ALR+VL TL R+AVVFGAGG+RD GKR PMGR+AA+LADLVV Sbjct 361 DFLALVDYAHKPGALRAVLETLRGQGTGRIAVVFGAGGNRDAGKREPMGRVAAELADLVV 420 Query 445 VTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKG 504 VTDDNPRDEDP IR I+AGA GG A VVE+ DRR+AI HAV WAR GDVVL+AGKG Sbjct 421 VTDDNPRDEDPATIRAAIMAGARAAGGGADVVEVGDRREAIAHAVRWARSGDVVLVAGKG 480 Query 505 HETGQRGGGRVRPFDDRVELAAALEALERR 534 HETGQ GR PFDDRVELA E LE+R Sbjct 481 HETGQTAAGRTHPFDDRVELA---ELLEKR 507 >gi|120404500|ref|YP_954329.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium vanbaalenii PYR-1] gi|119957318|gb|ABM14323.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium vanbaalenii PYR-1] Length=497 Score = 572 bits (1473), Expect = 8e-161, Method: Compositional matrix adjust. Identities = 336/475 (71%), Positives = 370/475 (78%), Gaps = 6/475 (1%) Query 59 DRTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA 118 D VTGVTLR QD PGDLFAAL GS HG R+ +A+ RGAVAVLTD AG AEIA R A Sbjct 18 DVQVTGVTLRGQDAQPGDLFAALPGSRAHGGRYAAEAVGRGAVAVLTDAAGEAEIASRGA 77 Query 119 --VPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAG 176 VPVLVHP PR VLG LA+ VYG PS+ L VIG+TGTSGKTTTTYLVEAGLRAAGRVAG Sbjct 78 PDVPVLVHPDPRAVLGELASAVYGRPSQHLRVIGVTGTSGKTTTTYLVEAGLRAAGRVAG 137 Query 177 LIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRF 236 LIGT+G+R+ G P LTTPEAP LQA+LA M+E+GVDTVVMEVSSHAL LGRVDG F Sbjct 138 LIGTVGVRIDGRQQPGGLTTPEAPELQALLATMLEQGVDTVVMEVSSHALTLGRVDGVSF 197 Query 237 AVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADA 296 AVG FTNLSRDHLDFHP+M DYF+AKA LFDP A A +V+C+DD+ GRAMAARA Sbjct 198 AVGGFTNLSRDHLDFHPTMEDYFDAKARLFDPACATHAARSVICVDDEWGRAMAARARRP 257 Query 297 ITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILD 356 +TVS PA WRA V G Q F A+DPAGV H + I LPG YNVANCL+A+A+LD Sbjct 258 VTVSTTG-PADWRAEQVRSAGGGAQDFVAVDPAGVHHGLEIGLPGGYNVANCLLAIALLD 316 Query 357 TVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTL-AHPDRRLA 415 VGVSPEQA PG+R+ VPGRLE +DRGQ FLALVDYAHKP ALR+VL TL RLA Sbjct 317 AVGVSPEQAAPGVRDATVPGRLESVDRGQPFLALVDYAHKPGALRAVLQTLREQCTGRLA 376 Query 416 VVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQV 475 VVFGAGG+RD GKR PMGR+AA+LADLVVVTDDNPRDEDP IR ILAGAA A+V Sbjct 377 VVFGAGGNRDQGKREPMGRVAAELADLVVVTDDNPRDEDPAVIRAAILAGAAGA--RAEV 434 Query 476 VEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEA 530 VEI DRR AI HA WAR GD+VLIAGKGHE GQ GG+ RPFDDR ELAAALEA Sbjct 435 VEIGDRRAAIGHAAGWARAGDIVLIAGKGHEAGQTSGGQTRPFDDRDELAAALEA 489 >gi|118472293|ref|YP_888509.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium smegmatis str. MC2 155] gi|118173580|gb|ABK74476.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Mycobacterium smegmatis str. MC2 155] Length=520 Score = 568 bits (1465), Expect = 7e-160, Method: Compositional matrix adjust. Identities = 349/507 (69%), Positives = 388/507 (77%), Gaps = 2/507 (0%) Query 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRT-VTGVTLRAQDVSPGDLFAALTGS 84 LRP+ VG LA LA VGA +E PA + VTGVTLR QD PGDLFAAL G+ Sbjct 5 LRPSRPVGHHLAPLAAAVGAVASENPAGSSSDLAAVHVTGVTLRGQDAQPGDLFAALPGA 64 Query 85 TTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATVYGHPSE 144 + HGAR DA+A GAVAVLTDP+G +AG VPVLVHPAPR VLG AA VYG P+E Sbjct 65 SAHGARFAADAVAAGAVAVLTDPSGADLLAGTLDVPVLVHPAPRSVLGEAAAIVYGRPAE 124 Query 145 RLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQA 204 RL V+G+TGTSGKTTTTYL EAGLRAAGRVAGLIGT+G+R+ G DLPSALTTPEAP LQA Sbjct 125 RLRVVGVTGTSGKTTTTYLAEAGLRAAGRVAGLIGTVGVRIDGTDLPSALTTPEAPALQA 184 Query 205 MLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKAS 264 +LA MVERGVDTVVMEVSSHALA GRVDG FAVG FTNLSRDHLDFHP+MADYFEAKA Sbjct 185 LLALMVERGVDTVVMEVSSHALAQGRVDGIGFAVGGFTNLSRDHLDFHPTMADYFEAKAR 244 Query 265 LFDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFT 324 LFDP S A AV+C+DD G MAARA +TVS + A WR + G Q+F Sbjct 245 LFDPQSPNHAAAAVICVDDQYGVQMAARAETPLTVSTSGAAADWRVEKITTAGPGAQEFV 304 Query 325 AIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRG 384 +DP G+ H +G+ LPGRYNVAN +A+A+LD VGVSPEQA PGLR VPGRLE ID G Sbjct 305 LVDPGGMHHQLGVGLPGRYNVANAALAVALLDAVGVSPEQAAPGLRTATVPGRLESIDLG 364 Query 385 QGFLALVDYAHKPEALRSVLTTL-AHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLV 443 Q FLALVDYAHKP AL++VL TL A RR+AVVFGAGGDRDPGKR PMGR+ A+LADLV Sbjct 365 QDFLALVDYAHKPGALQAVLETLRAAEPRRIAVVFGAGGDRDPGKREPMGRVTAELADLV 424 Query 444 VVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGK 503 VVTDDNPR EDP IR ILAGA V DA++VEI DRR AI HAVAWA+PGD+VLIAGK Sbjct 425 VVTDDNPRSEDPATIRSAILAGARAVASDAEIVEIGDRRAAIDHAVAWAQPGDIVLIAGK 484 Query 504 GHETGQRGGGRVRPFDDRVELAAALEA 530 GHE+GQ G RPFDDR ELAAALEA Sbjct 485 GHESGQTVGDHTRPFDDRDELAAALEA 511 >gi|169629088|ref|YP_001702737.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Mycobacterium abscessus ATCC 19977] gi|169241055|emb|CAM62083.1| UDP-N-acetylmuramyl-tripeptide synthetase MurE [Mycobacterium abscessus] Length=515 Score = 553 bits (1425), Expect = 3e-155, Method: Compositional matrix adjust. Identities = 318/478 (67%), Positives = 365/478 (77%), Gaps = 10/478 (2%) Query 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-V 119 TV GVTLRAQD GDLFAAL G++THGA+ +A++ GA AVLTD AG +AG+ + Sbjct 36 TVGGVTLRAQDARTGDLFAALPGTSTHGAQFASEAVSAGAAAVLTDAAGAELVAGQGLDI 95 Query 120 PVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIG 179 VLVHP PR VLG LAATVYG PS L V+G+TGTSGKTTTTYLVEAGLRAAG+ GLIG Sbjct 96 AVLVHPVPRSVLGELAATVYGEPSRHLQVVGVTGTSGKTTTTYLVEAGLRAAGKRVGLIG 155 Query 180 TIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVG 239 T+G+R+ G D+PSALTTPEAP LQ +LA MV+RGVDTVVMEVSSHALAL RVDGTRFAVG Sbjct 156 TVGVRIDGEDVPSALTTPEAPALQELLAEMVQRGVDTVVMEVSSHALALNRVDGTRFAVG 215 Query 240 AFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMA--ARAA--D 295 AFTNLSRDHLDFHP M DYF KA LF DS RA +VVCIDDDAGRAMA AR A D Sbjct 216 AFTNLSRDHLDFHPDMQDYFATKARLFRRDSPQRAHRSVVCIDDDAGRAMAELAREAGPD 275 Query 296 AITVSAAD-RPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAI 354 TVS+ D A WR ++VA GGQ+F A P + I LPG YNVANCLVA+AI Sbjct 276 VTTVSSLDGGVADWRCSNVAVGHDGGQRFVANGP-DRDTELTIALPGHYNVANCLVAIAI 334 Query 355 LDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTL-AHPDRR 413 LD +GVS A PG+ VPGR+E + GQ FLA+VDYAHKP ALR+VL +L +H D R Sbjct 335 LDVLGVSAATAAPGIATAGVPGRMEAVAAGQPFLAVVDYAHKPGALRAVLESLRSHRDGR 394 Query 414 LAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDA 473 LAVVFGAGG+RD GKRA MG++AA+LADLVVVTDDNPR+E+P AIR EI++G G +A Sbjct 395 LAVVFGAGGNRDRGKRADMGKVAAELADLVVVTDDNPRNEEPAAIRTEIISGT--TGSEA 452 Query 474 QVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEAL 531 Q++EI DRR AI A WARPGD VL+AGKGHE+GQ+ G PFDDRVEL AALEAL Sbjct 453 QIIEIGDRRAAIDFATLWARPGDTVLVAGKGHESGQKTGDVTVPFDDRVELRAALEAL 510 >gi|289570275|ref|ZP_06450502.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE [Mycobacterium tuberculosis T17] gi|289544029|gb|EFD47677.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase MurE [Mycobacterium tuberculosis T17] Length=276 Score = 525 bits (1352), Expect = 8e-147, Method: Compositional matrix adjust. Identities = 275/276 (99%), Positives = 276/276 (100%), Gaps = 0/276 (0%) Query 1 VSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 +SSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR Sbjct 1 MSSLARGISRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDR 60 Query 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP Sbjct 61 TVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVP 120 Query 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT Sbjct 121 VLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGT 180 Query 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA Sbjct 181 IGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGA 240 Query 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRART 276 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRART Sbjct 241 FTNLSRDHLDFHPSMADYFEAKASLFDPDSALRART 276 >gi|333918993|ref|YP_004492574.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Amycolicicoccus subflavus DQS3-9A1] gi|333481214|gb|AEF39774.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Amycolicicoccus subflavus DQS3-9A1] Length=533 Score = 489 bits (1260), Expect = 4e-136, Method: Compositional matrix adjust. Identities = 292/519 (57%), Positives = 356/519 (69%), Gaps = 12/519 (2%) Query 23 PTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALT 82 P+ RP+ + L+ L GA A GP E +TV+GV LRAQ V GDLFAAL Sbjct 14 PSSPRPSTLPPTPLSELLVVSGARAAAGPP----VEAKTVSGVELRAQHVVDGDLFAALP 69 Query 83 GSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATVYGHP 142 G+ HGA + A+ARGA A+LTD AG+A ++ VPVLVH PR +LG AA +YG+P Sbjct 70 GARAHGASFIPGALARGAAAILTDEAGLAHVSSDIQVPVLVHDEPRRILGDTAARIYGNP 129 Query 143 SERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTL 202 S++L +IGITGTSGKTTT YL+E GL AAG AGLIGT+ R+ G +PSALTTPEAP L Sbjct 130 SDKLQLIGITGTSGKTTTAYLIEGGLVAAGLRAGLIGTVETRIEGKPVPSALTTPEAPQL 189 Query 203 QAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAK 262 QA+LA M ERG+D+VVMEVSSHALALGRVDG FAVG FTNLS DHLDFH M DYF+ K Sbjct 190 QALLAVMAERGIDSVVMEVSSHALALGRVDGCHFAVGGFTNLSHDHLDFHRDMEDYFDTK 249 Query 263 ASLFDPDSALRARTAVVCIDDDAGRAMAARA-ADAITVSAADRPAHWRATDVAPTDAGGQ 321 A LF +S ++ AV+C+DDD GR MA A D +TVSA PA W A G Q Sbjct 250 ARLFVAESRVKCERAVICVDDDWGRRMADCAEGDVVTVSADGHPAQWLARSAHVVSTGVQ 309 Query 322 QFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQI 381 F A G + + +RLPGRYNVAN L+ALAILD G + QA GL +++VPGR+E+I Sbjct 310 AFAAERSDGRQYDVTVRLPGRYNVANALLALAILDAAGANTTQAARGLADVQVPGRVERI 369 Query 382 DRGQGFLALVDYAHKPEALRSVLTTL-AHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLA 440 DRGQ FLA+VDYAHKP A+ +VL TL A ++A+V GAGG+RD GKR PMG +A+ + Sbjct 370 DRGQPFLAVVDYAHKPGAVEAVLATLRAQARGKIALVIGAGGNRDTGKRQPMGEASARGS 429 Query 441 DLVVVTDDNPRDEDPTAIRREILAGAAEV--GGDAQVVEIADRRDAIRHAVAWARP---- 494 D+V++TDDNPRDED +AIR E+LAGA V A++ EI DR AIR AV W Sbjct 430 DVVIITDDNPRDEDSSAIRAEMLAGARRVPEAERAEIQEIGDRAKAIRVAVEWVAAHGIG 489 Query 495 GDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALER 533 DVVL+AGKGHETGQ G PFDDR+ LA A++A R Sbjct 490 DDVVLVAGKGHETGQEIRGVKHPFDDRLILADAIDAALR 528 >gi|307084812|ref|ZP_07493925.1| putative Mur ligase family, glutamate ligase domain protein [Mycobacterium tuberculosis SUMu012] gi|308365619|gb|EFP54470.1| putative Mur ligase family, glutamate ligase domain protein [Mycobacterium tuberculosis SUMu012] Length=250 Score = 486 bits (1252), Expect = 3e-135, Method: Compositional matrix adjust. Identities = 249/249 (100%), Positives = 249/249 (100%), Gaps = 0/249 (0%) Query 287 RAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVA 346 RAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVA Sbjct 2 RAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVA 61 Query 347 NCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTT 406 NCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTT Sbjct 62 NCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTT 121 Query 407 LAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGA 466 LAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGA Sbjct 122 LAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGA 181 Query 467 AEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAA 526 AEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAA Sbjct 182 AEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAA 241 Query 527 ALEALERRA 535 ALEALERRA Sbjct 242 ALEALERRA 250 >gi|289443663|ref|ZP_06433407.1| UDP-N-acetylMuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Mycobacterium tuberculosis T46] gi|289416582|gb|EFD13822.1| UDP-N-acetylMuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Mycobacterium tuberculosis T46] Length=247 Score = 484 bits (1245), Expect = 2e-134, Method: Compositional matrix adjust. Identities = 247/247 (100%), Positives = 247/247 (100%), Gaps = 0/247 (0%) Query 289 MAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANC 348 MAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANC Sbjct 1 MAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANC 60 Query 349 LVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLA 408 LVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLA Sbjct 61 LVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLA 120 Query 409 HPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAE 468 HPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAE Sbjct 121 HPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAE 180 Query 469 VGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAAL 528 VGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAAL Sbjct 181 VGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAAL 240 Query 529 EALERRA 535 EALERRA Sbjct 241 EALERRA 247 >gi|226307044|ref|YP_002767004.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase [Rhodococcus erythropolis PR4] gi|226186161|dbj|BAH34265.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase [Rhodococcus erythropolis PR4] Length=544 Score = 476 bits (1226), Expect = 3e-132, Method: Compositional matrix adjust. Identities = 280/519 (54%), Positives = 350/519 (68%), Gaps = 14/519 (2%) Query 16 ATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPG 75 ++ + AP G RP V + AL++ GA L + + + V GV LRAQ + Sbjct 7 SSNSDGAP-GTRPTQPVATAITALSELSGARLEWVGQPGSQSSEVVVKGVDLRAQGIVAD 65 Query 76 DLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVA--EIAGRA---AVPVLVHPAPRGV 130 DLFAAL G+ THGA+ DA+ RGA A+LTD AG+ E AG+A +VPVLVHP PR V Sbjct 66 DLFAALPGARTHGAQFAVDALGRGATAILTDEAGLELIEAAGKAPDRSVPVLVHPNPRDV 125 Query 131 LGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADL 190 LG ++A +YG PSE++ V+GITGTSGKTTT+YL+EA + AGR GL+GTI R+ G + Sbjct 126 LGEISAEIYGRPSEKMQVVGITGTSGKTTTSYLLEAAIAGAGRKPGLVGTIETRIDGRRV 185 Query 191 PSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLD 250 PSALTTPEAP L A+ A M E+G+DTVVMEVSSHALALGRVDG RF +GAFTNLS+DHLD Sbjct 186 PSALTTPEAPQLHALFAVMAEQGIDTVVMEVSSHALALGRVDGIRFDIGAFTNLSQDHLD 245 Query 251 FHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAA----DAI-TVSAADRP 305 FH +YF+AKA LFDP+S +RA AVVC+DD GR MA AA DA+ TVS + Sbjct 246 FHRDFEEYFQAKARLFDPESTVRAEHAVVCVDDVWGRRMAELAATDESDAVTTVSTSTAE 305 Query 306 AHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQA 365 A W+ V + G Q F + P G + +RLPGRYNVAN +AL + G+ P+ A Sbjct 306 AEWKVGAVEVAEDGSQTFELVGPDGQSWPVSLRLPGRYNVANAALALTVSFAAGLDPDAA 365 Query 366 VPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHP-DRRLAVVFGAGGDR 424 V L + VPGR+++IDRGQ FLA+VDYAHKP AL +V+ TL + R+AVV GAGGDR Sbjct 366 VRALGTVDVPGRVQRIDRGQSFLAVVDYAHKPAALEAVIATLRNQVPGRVAVVVGAGGDR 425 Query 425 DPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEV--GGDAQVVEIADRR 482 D GKR MG A+ ADL++VTDDNPR EDP IR ++ GA +V ++ E+ DR Sbjct 426 DAGKRTLMGEAGARGADLLIVTDDNPRTEDPAKIRASVMQGAIDVPESERGEIREVGDRA 485 Query 483 DAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDR 521 AI AV WA+PGDVVL+AGKGHE GQ G PFDDR Sbjct 486 LAIEQAVRWAQPGDVVLVAGKGHEVGQEIDGVKHPFDDR 524 >gi|312140147|ref|YP_004007483.1| UDP-N-acetylmuramoyl-l-alanyl-d-glutamate-2,6-dia minopimelate ligase mure [Rhodococcus equi 103S] gi|311889486|emb|CBH48803.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-2,6-diaminopimelate ligase MurE [Rhodococcus equi 103S] Length=547 Score = 475 bits (1223), Expect = 7e-132, Method: Compositional matrix adjust. Identities = 302/524 (58%), Positives = 354/524 (68%), Gaps = 19/524 (3%) Query 21 AAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAA 80 AA GLRP L LA ++GA L + A + VTGV LRAQ V GDLFAA Sbjct 13 AAVGGLRPENPPFTALTDLAARIGARLEWIGSPGA--DAGEVTGVELRAQAVRRGDLFAA 70 Query 81 LTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIA-----GRAAVPVLVHPAPRGVLGGLA 135 L G+ THGA VG AIA GA AVLTD AGVA +A A++PVLVHP PR VLG + Sbjct 71 LPGAHTHGAEFVGVAIAAGASAVLTDDAGVAMLAAGTEESAASLPVLVHPDPRQVLGEAS 130 Query 136 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 195 AT+YGHPSE + +IGITGTSGKTTT+YLVEAGL AAG GL+GTI RV G +PSALT Sbjct 131 ATIYGHPSEHMQIIGITGTSGKTTTSYLVEAGLAAAGHTIGLVGTIETRVAGHRVPSALT 190 Query 196 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 255 TPEAP L A+ AAM ERG+DTVVMEVSSHALALGRVDG RF++GAFTNLS+DHLDFH Sbjct 191 TPEAPQLHALFAAMRERGIDTVVMEVSSHALALGRVDGVRFSIGAFTNLSQDHLDFHKDF 250 Query 256 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARA-------ADAITVSAADRPAHW 308 DYF AK+ LF DSA+ A+ AV+C DD G MA A ADA+ + PA W Sbjct 251 DDYFNAKSRLFAADSAVCAQRAVICTDDRWGVRMAEIARHAHPADADAVETVSTHPPADW 310 Query 309 RATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPG 368 AT + +D G Q FT P G +RLPG YNVAN +A AI + G + A+ G Sbjct 311 TATATSSSDTGNQVFTLTGPDGTPRTATLRLPGHYNVANAALAAAICCSAGADVDAALAG 370 Query 369 LREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTL-AHPDRRLAVVFGAGGDRDPG 427 + + VPGR+E+++RGQ FLA+VDYAHKP AL +V+ TL R+AVV GAGGDRD G Sbjct 371 IANVDVPGRVERVERGQDFLAVVDYAHKPAALEAVIATLRGQTKGRIAVVVGAGGDRDRG 430 Query 428 KRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQ---VVEIADRRDA 484 KR MG A+ ADL+VVTDDNPR EDP AIR ++LAGA V DA+ V EI DR +A Sbjct 431 KRPLMGEAGARGADLLVVTDDNPRTEDPAAIRAQMLAGAVAV-PDAERGAVREIGDRAEA 489 Query 485 IRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAAL 528 I AV WAR GDVVL+AGKGHE+GQ G PFDDR LAAA+ Sbjct 490 IAAAVRWARTGDVVLVAGKGHESGQEVHGVKHPFDDREVLAAAI 533 >gi|229490463|ref|ZP_04384304.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodococcus erythropolis SK121] gi|229322753|gb|EEN88533.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodococcus erythropolis SK121] Length=544 Score = 475 bits (1222), Expect = 9e-132, Method: Compositional matrix adjust. Identities = 281/519 (55%), Positives = 349/519 (68%), Gaps = 14/519 (2%) Query 16 ATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPG 75 ++ + AP G RP V + AL++ GA L + + + V GV LRAQ + Sbjct 7 SSNSDGAP-GTRPTQPVATAITALSELSGARLEWVGLPGSQSSEVVVKGVDLRAQGIVTD 65 Query 76 DLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVA--EIAGRA---AVPVLVHPAPRGV 130 DLFAAL G+ THGA+ DA+ RGA A+LTD AG+ E A +A +VPVLVHP PR V Sbjct 66 DLFAALPGARTHGAQFAVDALGRGATAILTDEAGLELIEAADKAPDRSVPVLVHPNPRDV 125 Query 131 LGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADL 190 LG ++A +YG PSE++ V+GITGTSGKTTT+YL+EA + AGR GL+GTI R+ G + Sbjct 126 LGEISAEIYGRPSEKMQVVGITGTSGKTTTSYLLEAAIAGAGRKPGLVGTIETRIDGRRV 185 Query 191 PSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLD 250 PSALTTPEAP L A+ A M E+G+DTVVMEVSSHALALGRVDG RF +GAFTNLS+DHLD Sbjct 186 PSALTTPEAPQLHALFAVMAEQGIDTVVMEVSSHALALGRVDGIRFDIGAFTNLSQDHLD 245 Query 251 FHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAA----DAI-TVSAADRP 305 FH +YF+AKA LFDP+S +RA AVVC+DD GR MA AA DA+ TVS + Sbjct 246 FHRDFEEYFQAKARLFDPESTVRAEHAVVCVDDVWGRRMAELAATDESDAVTTVSTSTAE 305 Query 306 AHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQA 365 A W V + G Q F + P G + +RLPGRYNVAN +AL + G+ P+ A Sbjct 306 AEWTVGAVEVAEDGSQTFELVGPDGQSWPVSLRLPGRYNVANAALALTVSFAAGLDPDAA 365 Query 366 VPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLAHP-DRRLAVVFGAGGDR 424 V L + VPGR+++IDRGQ FLA+VDYAHKP AL +V+ TL + R+AVV GAGGDR Sbjct 366 VRALGTVDVPGRVQRIDRGQSFLAVVDYAHKPAALEAVIATLRNQVPGRVAVVVGAGGDR 425 Query 425 DPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEV--GGDAQVVEIADRR 482 D GKRA MG A+ ADL++VTDDNPR EDP IR ++ GA +V +V E+ DR Sbjct 426 DAGKRALMGEAGARGADLLIVTDDNPRTEDPAKIRASVMQGAMDVPESERGEVREVGDRA 485 Query 483 DAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDR 521 AI AV WA+PGDVVL+AGKGHE GQ G PFDDR Sbjct 486 AAIEQAVRWAQPGDVVLVAGKGHEVGQEIDGVKHPFDDR 524 >gi|325676972|ref|ZP_08156644.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodococcus equi ATCC 33707] gi|325552272|gb|EGD21962.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodococcus equi ATCC 33707] Length=547 Score = 474 bits (1221), Expect = 1e-131, Method: Compositional matrix adjust. Identities = 300/523 (58%), Positives = 351/523 (68%), Gaps = 17/523 (3%) Query 21 AAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAA 80 AA GLRP L LA ++GA L + A + VTGV LRAQ V GDLFAA Sbjct 13 AAVGGLRPENPPFTALTDLAARIGARLEWIGSPGA--DAGEVTGVELRAQAVRRGDLFAA 70 Query 81 LTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIA-----GRAAVPVLVHPAPRGVLGGLA 135 L G+ THGA V AIA GA AVLTD AGVA +A A++PVLVHP PR VLG + Sbjct 71 LPGAHTHGAEFVSVAIAAGASAVLTDDAGVAMLAAGTEESAASLPVLVHPDPRQVLGEAS 130 Query 136 ATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALT 195 AT+YGHPSE + +IGITGTSGKTTT+YLVEAGL AAG GL+GTI RV G +PSALT Sbjct 131 ATIYGHPSEHMQIIGITGTSGKTTTSYLVEAGLAAAGHTIGLVGTIETRVAGHRVPSALT 190 Query 196 TPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSM 255 TPEAP L A+ AAM ERG+DTVVMEVSSHALALGRVDG RF++GAFTNLS+DHLDFH Sbjct 191 TPEAPQLHALFAAMRERGIDTVVMEVSSHALALGRVDGVRFSIGAFTNLSQDHLDFHKDF 250 Query 256 ADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARA-------ADAITVSAADRPAHW 308 DYF AK+ LF DSA+ A+ AV+C DD G MA A ADA+ + PA W Sbjct 251 DDYFNAKSRLFAADSAVCAQRAVICTDDRWGVRMAEIARHAHPADADAVETVSTHPPADW 310 Query 309 RATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPG 368 AT + +D G Q FT P G +RLPG YNVAN +A AI + G + A+ G Sbjct 311 TATATSSSDTGNQVFTLTGPDGTPRTATLRLPGHYNVANAALAAAICCSAGADVDAALAG 370 Query 369 LREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTL-AHPDRRLAVVFGAGGDRDPG 427 + + VPGR+E+++RGQ FLA+VDYAHKP AL +V+ TL R+AVV GAGGDRD G Sbjct 371 IANVDVPGRVERVERGQDFLAVVDYAHKPAALEAVIATLRGQTKGRIAVVVGAGGDRDRG 430 Query 428 KRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEV--GGDAQVVEIADRRDAI 485 KR MG A+ ADL+VVTDDNPR EDP AIR ++LAGA V +V EI DR DAI Sbjct 431 KRPLMGEAGARGADLLVVTDDNPRTEDPAAIRAQMLAGAVAVPDAERGEVREIGDRADAI 490 Query 486 RHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAAL 528 AV WAR GDVVL+AGKGHE+GQ G PFDDR LAAA+ Sbjct 491 AAAVRWARTGDVVLVAGKGHESGQEVHGVKHPFDDREVLAAAI 533 >gi|326382555|ref|ZP_08204246.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Gordonia neofelifaecis NRRL B-59395] gi|326198674|gb|EGD55857.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Gordonia neofelifaecis NRRL B-59395] Length=689 Score = 473 bits (1218), Expect = 3e-131, Method: Compositional matrix adjust. Identities = 290/493 (59%), Positives = 327/493 (67%), Gaps = 10/493 (2%) Query 45 AALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVL 104 +ALA G +DR V+G TLRAQD G LFAAL G THGA + A A GA VL Sbjct 25 SALAAGFGLELHGDDRDVSGATLRAQDAGAGYLFAALPGDRTHGANYAAQARAAGAAGVL 84 Query 105 TDPAGVA---EIAGRAAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTT 161 TDPAG+A E A V VLVH PR VLG ++A +YG PS RLT+IGITGTSGKTTT Sbjct 85 TDPAGLALIREDPEAADVTVLVHARPREVLGAVSARIYGDPSSRLTLIGITGTSGKTTTA 144 Query 162 YLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEV 221 YL EA LRAAGRV GL+GT+ IRV G +PS+LTTPEAP LQ M A M ERGVDTVVMEV Sbjct 145 YLAEAALRAAGRVVGLVGTVEIRVDGTVVPSSLTTPEAPDLQRMFAVMAERGVDTVVMEV 204 Query 222 SSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCI 281 SSHALALGRVDG FAVG FTNLS+DHLD+H +M +YF AKA LF+ S RAR A VC+ Sbjct 205 SSHALALGRVDGCHFAVGGFTNLSQDHLDYHRTMDEYFAAKARLFEAGSPTRARQAAVCV 264 Query 282 DDDAGR----AMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGI 337 DD GR A AA ITVS PA W TDAG Q P G + + Sbjct 265 DDVWGRRAADVAAQGAATPITVSTTG-PADWSVVRTVRTDAGSQTVLIAGPDGAETEMTV 323 Query 338 RLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKP 397 LPG YNVAN L+A+A+ G + AV GL + VPGRLE+++RGQ FLA+VDYAHKP Sbjct 324 PLPGAYNVANALLAVAMTVAAGTDVDTAVAGLAHVAVPGRLEKVERGQEFLAVVDYAHKP 383 Query 398 EALRSVLTTLAHPDR-RLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPT 456 A+ +VL TL R RLAVV GAGGDRD KR MG AA+ ADLV+VTDDNPR E P Sbjct 384 AAVEAVLATLGAQTRGRLAVVLGAGGDRDTEKRPLMGAAAARGADLVIVTDDNPRSEPPA 443 Query 457 AIRREILAGAAEV-GGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRV 515 IR +LAGA V ++ EI DRRDAI AV WARPGDVVLIAGKGHE GQ G Sbjct 444 DIRAAVLAGARSVDAARGEIREIGDRRDAIAAAVDWARPGDVVLIAGKGHEKGQEIDGVK 503 Query 516 RPFDDRVELAAAL 528 PFDDR L L Sbjct 504 HPFDDRQVLGELL 516 >gi|226360235|ref|YP_002778013.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodococcus opacus B4] gi|226238720|dbj|BAH49068.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase [Rhodococcus opacus B4] Length=524 Score = 471 bits (1213), Expect = 1e-130, Method: Compositional matrix adjust. Identities = 286/515 (56%), Positives = 347/515 (68%), Gaps = 13/515 (2%) Query 25 GLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGS 84 GLRP V ++ALA GA + E P+ A E VTGV LRAQ + GDLFAAL G+ Sbjct 6 GLRPAQPVRTTVSALAALAGARV-EAPSGTA--EHVIVTGVDLRAQGIVEGDLFAALPGA 62 Query 85 TTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLAATVYGHPS 143 HGA DA+ RGA A+LTD AG+A ++ PVLVH PRGVLG L+AT+YG PS Sbjct 63 RAHGAEFAADALDRGATAILTDEAGLALVSALGTDAPVLVHDDPRGVLGELSATIYGRPS 122 Query 144 ERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQ 203 E++ VIGITGTSGKTTT+YLVE L AAGR GL+GTI R+ G +PSALTTPEAP L Sbjct 123 EKMQVIGITGTSGKTTTSYLVEGALNAAGRTTGLVGTIETRMSGRRVPSALTTPEAPQLH 182 Query 204 AMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKA 263 A+ A M+E+G+DTVVMEVSSHAL+LGRVDG RF VGAFTNLS+DHLDFH DYF AKA Sbjct 183 ALFAVMLEQGIDTVVMEVSSHALSLGRVDGVRFDVGAFTNLSQDHLDFHRDFEDYFAAKA 242 Query 264 SLFDPDSALRARTAVVCIDDDAGRAMA--ARAADAITVSAADRP----AHWRATDVAPTD 317 LF +S++ A+ AV+C+DD GR MA AR A +I + A P A W A + Sbjct 243 RLFAAESSVHAQHAVICVDDVWGRRMAEVARGAHSIVTTVATTPETGGAVWTAGPATVSA 302 Query 318 AGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGR 377 +G Q+F G + +RLPG+YNVAN +A+A+ +GV P AV G+ + VPGR Sbjct 303 SGSQKFALTTAEGTTLDVELRLPGQYNVANASLAVALCAVLGVDPRDAVAGIAGVDVPGR 362 Query 378 LEQIDRGQGFLALVDYAHKPEALRSVLTTLAHPDR-RLAVVFGAGGDRDPGKRAPMGRIA 436 +++IDRGQ FLA+VDYAHKP A+ +V+ TL R R+AVV GAGGDRD GKR MG A Sbjct 363 VQRIDRGQDFLAVVDYAHKPAAVEAVIATLREQARGRVAVVVGAGGDRDAGKRPLMGAAA 422 Query 437 AQLADLVVVTDDNPRDEDPTAIRREILAGAAEV--GGDAQVVEIADRRDAIRHAVAWARP 494 A+ ADL+++TDDNPR EDP IR I GA V QV E+ADR AI AV WA+ Sbjct 423 ARGADLLIITDDNPRTEDPATIRAAIREGALGVPESERGQVWEVADRAKAIADAVGWAQA 482 Query 495 GDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALE 529 GDVVL+AGKGHE GQ G PFDDR L A+E Sbjct 483 GDVVLVAGKGHEIGQEIHGVKYPFDDRAVLGDAIE 517 >gi|343924205|ref|ZP_08763768.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [Gordonia alkanivorans NBRC 16433] gi|343766010|dbj|GAA10694.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [Gordonia alkanivorans NBRC 16433] Length=561 Score = 455 bits (1170), Expect = 9e-126, Method: Compositional matrix adjust. Identities = 287/499 (58%), Positives = 341/499 (69%), Gaps = 23/499 (4%) Query 59 DRTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIA---- 114 D +V GVTLRAQDV PGDLFAAL G+ THGAR A+A GA A+LTDPAG AE++ Sbjct 52 DTSVQGVTLRAQDVQPGDLFAALPGAATHGARFADQAVAAGATAILTDPAGRAELSRVLP 111 Query 115 GRAAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRV 174 AV VL+HPAPR VLG ++A VYG+PS+RL +IGITGTSGKTTT+YLVEA L AAG Sbjct 112 PETAVAVLIHPAPRTVLGSVSARVYGNPSQRLKLIGITGTSGKTTTSYLVEAALLAAGHS 171 Query 175 AGLIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGT 234 GLIGT+ RV G PS+LTTPEAPTLQA+LA+M+E GVD VVMEVSSHAL+LGRVDG Sbjct 172 VGLIGTVETRVNGVAQPSSLTTPEAPTLQALLASMLEDGVDVVVMEVSSHALSLGRVDGA 231 Query 235 RFAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMA---- 290 FA+GAFTNLS+DHLDFH +M YF+AKA LF P S A AVVC+DD+ G+ MA Sbjct 232 HFAIGAFTNLSQDHLDFHQTMRAYFDAKAQLFVPSSPNHAVRAVVCVDDEWGQRMADLAR 291 Query 291 ----ARAADAITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVA 346 A +TVS PAHW A T G +P G H + + LPGRYNVA Sbjct 292 RPGEAAHLQPVTVSTGPTPAHWHAGPSDLTGEGTSHTPITEPDG-DHVLVMPLPGRYNVA 350 Query 347 NCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTT 406 N L+A+A+ GV A+ + + VPGRL+++DRGQ FLALVDYAHKP A+ +VL T Sbjct 351 NGLLAVAVAHAAGVPISTALDAVASVSVPGRLQRVDRGQPFLALVDYAHKPGAVEAVLAT 410 Query 407 ----LAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREI 462 L R+A+V GAGGDRD GKR MG AA+ A+LV+VTDDNPR E+P AIR E+ Sbjct 411 LRGQLGEGPGRVAIVVGAGGDRDAGKRPLMGEAAARGAELVIVTDDNPRSEEPAAIRSEV 470 Query 463 LAGAAEV------GGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVR 516 LAGA V G V E+ DR AI AVAWARPGD+VL+AGKGHE GQ G Sbjct 471 LAGARGVDAAERPAGAEPVREVGDRAAAIAEAVAWARPGDIVLVAGKGHEAGQEINGVKH 530 Query 517 PFDDRVELAAALEALERRA 535 PFDDR +A ALE+ R+ Sbjct 531 PFDDRDVVAQALESSTPRS 549 >gi|324998161|ref|ZP_08119273.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Pseudonocardia sp. P1] Length=534 Score = 454 bits (1169), Expect = 1e-125, Method: Compositional matrix adjust. Identities = 286/524 (55%), Positives = 335/524 (64%), Gaps = 20/524 (3%) Query 27 RPNAVVGVRLAALADQVGAAL-------AEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFA 79 RP V V +A L GA L GP A VTG TLRA V PGDLFA Sbjct 9 RPETVRPVDVALLGRLAGAELNPRTAGTGPGPLLDAAAGPHVVTGATLRAGSVRPGDLFA 68 Query 80 ALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLAATV 138 AL G+ HGA AIA GA AVLTD G R + +PVLVHPAPR VLG ++A + Sbjct 69 ALPGARAHGADFAAQAIAGGAAAVLTDADGADRPEIRHSRLPVLVHPAPREVLGPVSAAI 128 Query 139 YGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVG--GAD---LPSA 193 YG P+ RL V+G+TGTSGKTT +L+EAGL AAGR GL+GT+ RV G + LPSA Sbjct 129 YGEPTARLRVLGVTGTSGKTTVGHLLEAGLTAAGRSTGLLGTVRTRVQVPGEEPRALPSA 188 Query 194 LTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHP 253 TTPEAP LQA+ A MVE GV V MEVSSHALALGRV G+RFAVGAFTNLS+DHLDFHP Sbjct 189 FTTPEAPDLQALFAVMVEAGVTDVAMEVSSHALALGRVGGSRFAVGAFTNLSQDHLDFHP 248 Query 254 SMADYFEAKASLFDPDSALRA--RTAVVCIDDDAGRAMAARAADAITVSAADRPAH--WR 309 +M DYFEAKA LF A R VVCIDD+ GR +A+R DA+TV + H W Sbjct 249 TMTDYFEAKARLFGGGGAGVEAARHGVVCIDDEWGRQLASRRPDAVTVGSDPAGPHATWT 308 Query 310 ATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGL 369 D+A G Q FTA+ P G+ + + LPGRYNVAN LVALA LD G+ PE A G Sbjct 309 VRDLAAHPDGTQTFTAVGPGGLAQAVTLALPGRYNVANALVALACLDADGIPPEVAAQGF 368 Query 370 REIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTLA---HPDRRLAVVFGAGGDRDP 426 + VPGR++++D GQ +LA+VDYAHKP A+ ++L L HP R+ V G GGDRD Sbjct 369 ARLSVPGRMQRVDAGQPWLAVVDYAHKPAAVAALLDALRAQIHPHARVITVLGCGGDRDT 428 Query 427 GKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIR 486 GKR MG AA +D +VVTDDNPR E+P IRR +L GA V+EI DRR AI Sbjct 429 GKRPLMGAAAAIRSDTLVVTDDNPRGEEPATIRRAMLEGAMHEPARGDVIEIGDRRSAIV 488 Query 487 HAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEA 530 +AV ARPGD V+IAGKGHETGQ G PFDD EL A+ A Sbjct 489 YAVRSARPGDAVVIAGKGHETGQEVHGVKYPFDDADELVNAIRA 532 >gi|111018106|ref|YP_701078.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodococcus jostii RHA1] gi|110817636|gb|ABG92920.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Rhodococcus jostii RHA1] Length=537 Score = 450 bits (1158), Expect = 2e-124, Method: Compositional matrix adjust. Identities = 286/514 (56%), Positives = 346/514 (68%), Gaps = 13/514 (2%) Query 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 LRP V ++ALA GA + E P A E VTGV LRAQ + GDLFAAL G+ Sbjct 20 LRPAQPVRTTVSALAALAGARV-EAPTGTA--EHVIVTGVDLRAQGIVEGDLFAALPGAR 76 Query 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLAATVYGHPSE 144 HGA DA+ARGA A+LTD AG A ++ + +PVLVH PRGVLG L+AT+YG PSE Sbjct 77 AHGAEFAADALARGATAILTDEAGFALVSALGSDMPVLVHDDPRGVLGELSATIYGRPSE 136 Query 145 RLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQA 204 ++ VIGITGTSGKTTT+YLVEA L AAGR GL+GTI R+ G +PSALTTPEAP L A Sbjct 137 KMQVIGITGTSGKTTTSYLVEAALTAAGRTTGLVGTIETRMRGRRVPSALTTPEAPQLHA 196 Query 205 MLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKAS 264 + A M+E+G+DTVVMEVSSHAL+LGRVDG RF VGAFTNLS+DHLDFH DYF AKA Sbjct 197 LFAVMLEQGIDTVVMEVSSHALSLGRVDGVRFDVGAFTNLSQDHLDFHRDFEDYFAAKAR 256 Query 265 LFDPDSALRARTAVVCIDDDAGRAMA--ARAADAITVSAADRP----AHWRATDVAPTDA 318 LF DS++ A+ AV+CIDD G+ MA AR A +I + A P A W A + + Sbjct 257 LFAADSSVHAQHAVICIDDVWGQRMADVARGAHSIVTTVATTPDSEGAVWTAGPATVSPS 316 Query 319 GGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRL 378 G Q F G + +RLPG+YNVAN +A+A+ +GV P AV G+ + VPGR+ Sbjct 317 GSQTFALTTAEGTTLDVELRLPGQYNVANASLAVALCAALGVDPRDAVEGIAGVDVPGRV 376 Query 379 EQIDRGQGFLALVDYAHKPEALRSVLTTL-AHPDRRLAVVFGAGGDRDPGKRAPMGRIAA 437 ++IDRGQ FLA+VDYAHKP A+ +V+ TL R+AVV GAGGDRD GKR MG AA Sbjct 377 QRIDRGQDFLAVVDYAHKPAAVEAVIATLREQVRGRVAVVVGAGGDRDAGKRPLMGAAAA 436 Query 438 QLADLVVVTDDNPRDEDPTAIRREILAGAAEV--GGDAQVVEIADRRDAIRHAVAWARPG 495 + ADL+++TDDNPR EDP IR + GA V QV E+ADR AI AV WA+ G Sbjct 437 RGADLLIITDDNPRSEDPAKIRAAVREGALGVPESERGQVWEVADRAKAIADAVGWAQAG 496 Query 496 DVVLIAGKGHETGQRGGGRVRPFDDRVELAAALE 529 DVVL+AGKGHE GQ G PFDDR L A+E Sbjct 497 DVVLVAGKGHEIGQEIHGVKYPFDDRDVLGDAIE 530 >gi|262202914|ref|YP_003274122.1| UDP-N-acetylmuramyl-tripeptide synthetase [Gordonia bronchialis DSM 43247] gi|262086261|gb|ACY22229.1| UDP-N-acetylmuramyl-tripeptide synthetase [Gordonia bronchialis DSM 43247] Length=556 Score = 445 bits (1145), Expect = 7e-123, Method: Compositional matrix adjust. Identities = 301/547 (56%), Positives = 364/547 (67%), Gaps = 31/547 (5%) Query 9 SRRRTEVATQVEAAPTGLRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLR 68 SR ++ QV AA LRP +V ++ L+ GA L + TE VTGVTLR Sbjct 8 SRGTSKAGRQVSAA---LRPTSVAPTAVSVLSTSTGARLDLIGGAESATE---VTGVTLR 61 Query 69 AQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIA----GRAAVPVLVH 124 AQ+V GDLFAAL GSTTHGAR DA+A GA A+LTDPAG AE++ A+V LVH Sbjct 62 AQEVRSGDLFAALPGSTTHGARFAADAVAAGATAILTDPAGRAELSRVLPPEASVVALVH 121 Query 125 PAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIR 184 P PR VLGG++A +YG+PS+RL +IGITGTSGKTTT+Y+VEA L AAG GLIGT+ R Sbjct 122 PEPRTVLGGVSARIYGNPSQRLKLIGITGTSGKTTTSYMVEAALLAAGSSVGLIGTVETR 181 Query 185 VGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNL 244 + G PS+LTTPEAPTLQA+LA M+ERGVD VVMEVSSHALALGRVDG+ FA+GAFTNL Sbjct 182 IDGVAQPSSLTTPEAPTLQALLAVMLERGVDAVVMEVSSHALALGRVDGSHFALGAFTNL 241 Query 245 SRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADA-------- 296 S+DHLDFHP+MA YFEAKA LF P S + A +V+C+DD+ G MA A A Sbjct 242 SQDHLDFHPTMAAYFEAKAQLFVPSSPVHAVRSVICVDDEWGARMAELARPAARQSARQP 301 Query 297 ITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILD 356 +TVS PA W A + + DA G T I + + LPGRYNVAN L+A+A+ D Sbjct 302 VTVSTGGVPAQWHAAE-SVVDADGTSRTPITGTDGDAELVVPLPGRYNVANALLAVAVAD 360 Query 357 TVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVL------TTLAHP 410 GV A+ + + VPGRL+++DRGQ FLALVDYAHKP A+++VL Sbjct 361 CAGVDAATAIGAIATVSVPGRLQRVDRGQPFLALVDYAHKPGAVQAVLATLRAQAAARAE 420 Query 411 DRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVG 470 R+A+V GAGGDRD KR MG AA+ A+ VVVTDDNPR EDP AIR E+LAGA VG Sbjct 421 AGRVAIVIGAGGDRDTAKRPLMGEAAARGAEFVVVTDDNPRTEDPAAIRAEVLAGARAVG 480 Query 471 ------GDAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVEL 524 G +V E+ R +AI A+ WARPGD VLIAGKGHETGQ G PFDDR + Sbjct 481 RADRPAGAEEVREVGGRAEAIATALHWARPGDTVLIAGKGHETGQEINGVKHPFDDRDVV 540 Query 525 AAALEAL 531 A L+ L Sbjct 541 AQVLDGL 547 >gi|331696615|ref|YP_004332854.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [Pseudonocardia dioxanivorans CB1190] gi|326951304|gb|AEA25001.1| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [Pseudonocardia dioxanivorans CB1190] Length=501 Score = 445 bits (1144), Expect = 9e-123, Method: Compositional matrix adjust. Identities = 280/473 (60%), Positives = 322/473 (69%), Gaps = 4/473 (0%) Query 60 RTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA- 118 R VTG TLRA DV PGDLFAAL GS HGA A+A GAVA+LTDPAG A A A Sbjct 25 RPVTGATLRASDVRPGDLFAALPGSRAHGADFTAAALAAGAVAILTDPAGAAREAVAQAA 84 Query 119 VPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLI 178 VPVLVH APR VLG LAA +YG P+ RL V+G+TGTSGKTT +++EAGL A GR GL+ Sbjct 85 VPVLVHEAPRRVLGDLAARIYGDPTARLDVVGVTGTSGKTTVGHMLEAGLAAGGRATGLL 144 Query 179 GTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAV 238 GT+ R+ GA+ PS TTPE+P LQA+ A M ERGV V MEVSSHALAL RV GTRF+V Sbjct 145 GTVTTRIRGAEAPSLFTTPESPDLQALFAVMAERGVTDVAMEVSSHALALDRVAGTRFSV 204 Query 239 GAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAIT 298 AFTNLS+DHLDFH M DYFEAKA LFDP AR VVC+DD+ GR +A R DA+T Sbjct 205 AAFTNLSQDHLDFHRDMDDYFEAKALLFDPSRQGAARRRVVCVDDEWGRRLADRHPDAVT 264 Query 299 VSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTV 358 V A PA W A V D G Q F A P G + +RLPGRYNVAN LVALA LD Sbjct 265 V-ATTGPADWTAESVHQDDDGTQSFVAARPGGT-VPVRLRLPGRYNVANALVALACLDAA 322 Query 359 GVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTL-AHPDRRLAVV 417 GV E A P L E+ VPGR++++D GQ FL +VDYAHKP A+ ++L L R+ V Sbjct 323 GVPAEVAAPRLAELAVPGRMQRVDAGQDFLVVVDYAHKPAAVGALLAALRGQVGGRIVTV 382 Query 418 FGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVE 477 G GGDRD GKR MG IAA +DL+VVTDDNPR EDP AIRR + GA ++VE Sbjct 383 LGCGGDRDRGKRPLMGAIAAAGSDLLVVTDDNPRTEDPAAIRRAVREGAEAEPRRGEIVE 442 Query 478 IADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEA 530 I DRR AI AVA ARPGD V++AGKGHE GQ G PFDD E+ AAL + Sbjct 443 IGDRRAAIAAAVAAARPGDAVVVAGKGHEKGQEIDGVKHPFDDVDEVRAALRS 495 >gi|296394969|ref|YP_003659853.1| UDP-N-acetylmuramyl-tripeptide synthetase [Segniliparus rotundus DSM 44985] gi|296182116|gb|ADG99022.1| UDP-N-acetylmuramyl-tripeptide synthetase [Segniliparus rotundus DSM 44985] Length=506 Score = 434 bits (1117), Expect = 2e-119, Method: Compositional matrix adjust. Identities = 265/505 (53%), Positives = 323/505 (64%), Gaps = 9/505 (1%) Query 26 LRPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGST 85 LRP G ++ LAD GA + G E V GV AQ V PGDLF AL G+ Sbjct 5 LRPKRHPGAAISELADVAGAVVLAGD------ERGRVRGVAQAAQSVEPGDLFVALPGAR 58 Query 86 THGARHVGDAIARGAVAVLTDPAGVAEIAGRAAVPVLVHPAPRGVLGGLAATVYGHPSER 145 THGA + A RGA AVLTD AG A + G A+ VLV APR LG L A VYG PS R Sbjct 59 THGANFISVAQERGAAAVLTDEAGAACLGGTDAMAVLVAAAPRASLGALCALVYGDPSAR 118 Query 146 LTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAM 205 LTV+G+TGT+GKTTTTYL+E+ RAAGR G+IGT+ R+G + S+ TTPEAP Q++ Sbjct 119 LTVVGVTGTAGKTTTTYLLESLFRAAGRATGVIGTVETRIGSQSVASSFTTPEAPQTQSL 178 Query 206 LAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASL 265 LA M E GV+ V+MEVSSHAL GRVDGTRFA G FTNLS DHLD H M YF+AKA L Sbjct 179 LAVMAEAGVEVVLMEVSSHALDFGRVDGTRFAAGGFTNLSHDHLDHHGDMESYFQAKAKL 238 Query 266 FDPDSALRARTAVVCIDDDAGRAMAARAADAITVSAADRPAHWRATDVAPTDAGGQQFTA 325 F P S++ AR AV+C+DD G+ M+ A ++TV+ D A W + + G QQ Sbjct 239 FQPGSSVAARRAVICVDDSWGQRMSRVARGSVTVATGDEAADWAVLERREDELGAQQVLV 298 Query 326 IDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVS-PEQAVPGLREIRVPGRLEQIDRG 384 P + L GR+N AN ++A+ + + GV E+ V G +I VPGRLE++ G Sbjct 299 RGPRERQFAFRLGLLGRHNAANAVLAVGLAEATGVRVTEELVRGWADIAVPGRLERVQAG 358 Query 385 QGFLALVDYAHKPEALRSVLTTL-AHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLV 443 Q FLA+VDYAHKPE+L VL L H R+AVV GAGGDRD GKR MG ++A A+LV Sbjct 359 QDFLAVVDYAHKPESLAKVLQALREHTAGRIAVVVGAGGDRDQGKRPMMGEVSASGAELV 418 Query 444 VVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVVLIAGK 503 VVTDDNPR EDP AIR ++LAG A+ A+V E+A R +AI AV WAR GD VL+AGK Sbjct 419 VVTDDNPRSEDPAAIRAQVLAG-AQGSSRAEVWEVASRAEAIARAVRWARAGDTVLVAGK 477 Query 504 GHETGQRGGGRVRPFDDRVELAAAL 528 GHET Q G FDDR LA A+ Sbjct 478 GHETYQEVNGVKSHFDDREILARAI 502 >gi|237785338|ref|YP_002906043.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Corynebacterium kroppenstedtii DSM 44385] gi|237758250|gb|ACR17500.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6- diaminopimelate ligase [Corynebacterium kroppenstedtii DSM 44385] Length=526 Score = 434 bits (1116), Expect = 2e-119, Method: Compositional matrix adjust. Identities = 251/504 (50%), Positives = 315/504 (63%), Gaps = 41/504 (8%) Query 59 DRTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRAA 118 D VT + L AQ + G LFA + G HGA+ A + A AVLTD GV ++ R Sbjct 22 DLVVTDIGLNAQALPEGGLFAGVPGLHVHGAQF---ADSSSAAAVLTDHDGVEKVT-RED 77 Query 119 VPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLI 178 +P++V R VLG +++ VY HPS LTVIGITGT+GKTTT+Y+VEA L G GLI Sbjct 78 LPIIVVDDVRAVLGEVSSAVYDHPSRDLTVIGITGTAGKTTTSYMVEAALLHHGISTGLI 137 Query 179 GTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRFAV 238 GT G R+ G +PS LTTPEAP LQA+ A M +RGV VVMEVSSHA+ALGRV GT F+V Sbjct 138 GTTGTRINGEKVPSTLTTPEAPNLQALFAMMKKRGVTHVVMEVSSHAIALGRVLGTHFSV 197 Query 239 GAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAADAIT 298 FTNLS+DHLDFHP+M DYF+ KA LF DS L A T+VVCIDD G+ +A T Sbjct 198 AGFTNLSQDHLDFHPTMEDYFQTKARLFKEDSPLHAETSVVCIDDAWGQRLATMLPHPFT 257 Query 299 VS--------AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHH---IGIRLPGRYNVAN 347 VS A+ +P W P+ + G G + + I +PGR+NVAN Sbjct 258 VSTEAASEHDASLQPDVW----AGPSSVMDNGVQTAELYGFGANEMTLHIPMPGRFNVAN 313 Query 348 CLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTL 407 ++A+ +L G+ E A+ GL + VPGRLE+ID GQ F+A+VDYAHKP A+ +VL TL Sbjct 314 AMLAMGLLVKTGMKAEDAIEGLSTVTVPGRLERIDCGQDFMAVVDYAHKPGAIAAVLDTL 373 Query 408 -AHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGA 466 AH R+A+V GAGGDRD KR MGR AA +DLV+VTDDNPR EDP +IR++++AGA Sbjct 374 RAHVRGRIAIVVGAGGDRDHSKRPIMGREAALRSDLVIVTDDNPRSEDPASIRQQVVAGA 433 Query 467 AEVGGDAQV---------------------VEIADRRDAIRHAVAWARPGDVVLIAGKGH 505 EV V EI DRR+AIR A+ W +PGD V++AGKGH Sbjct 434 KEVADHVDVDRADEPRNKVKTEGSEHRPTIREIGDRREAIRAAIQWTQPGDAVIVAGKGH 493 Query 506 ETGQRGGGRVRPFDDRVELAAALE 529 ETGQ G PFDDRVE ++E Sbjct 494 ETGQLIGDTTHPFDDRVETRRSIE 517 >gi|54023729|ref|YP_117971.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Nocardia farcinica IFM 10152] gi|54015237|dbj|BAD56607.1| putative UDP-N-acetylmuramoylalanyl-D-glutamate- 2,6-diaminopimelate ligase [Nocardia farcinica IFM 10152] Length=536 Score = 431 bits (1108), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 285/478 (60%), Positives = 324/478 (68%), Gaps = 17/478 (3%) Query 56 VTEDRTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAG 115 V D VTG+ R+ V PGDLFAAL G+ HGAR DA+ARGAVAV TD G + G Sbjct 47 VPADVVVTGIEQRSGAVQPGDLFAALPGAHAHGARFAHDAVARGAVAVFTDAEGARVLDG 106 Query 116 RAAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVA 175 VPVLV PR VLG L+A VYG PS+RL +IGITGTSGKTTT+YLVEAGL AAG Sbjct 107 -LTVPVLVRERPREVLGELSAAVYGQPSQRLRLIGITGTSGKTTTSYLVEAGLAAAGLST 165 Query 176 GLIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTR 235 LIGTI R+GG +PSALTTPEAP L AM A MVE+GV VVMEVSSHALALGRVDG R Sbjct 166 ALIGTIETRIGGRRVPSALTTPEAPQLHAMFALMVEQGVQAVVMEVSSHALALGRVDGVR 225 Query 236 FAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAARAAD 295 F VGAFTNLS+DHLDFH DYF AK LF+P S + ARTAVVC+DD GR +A A Sbjct 226 FDVGAFTNLSQDHLDFHADFEDYFAAKRRLFEPQSPVAARTAVVCVDDAWGRRLAEGLAA 285 Query 296 AITVSAADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGI--RLPGRYNVANCLVALA 353 ITVS A WR T Q+FTA PAG +G+ RLPGRYNVAN L+A+A Sbjct 286 PITVSTTGE-ADWRVAGGVATVGAEQEFTAAGPAG---ELGVRLRLPGRYNVANALLAVA 341 Query 354 ILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTL------ 407 + P A P L + VPGR+++++RGQ FLA+VDYAHKP AL SV+ TL Sbjct 342 VCAAARADPAVAAPALATVDVPGRMQRVERGQDFLAVVDYAHKPAALESVIATLREHLAA 401 Query 408 AHPDR--RLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAG 465 A P+ RLAVV GAGGDRD GKRA MG A+ ADL+V+TDDNPR EDP IR + AG Sbjct 402 ADPEHPGRLAVVVGAGGDRDAGKRALMGAAGARGADLLVITDDNPRTEDPATIRAALRAG 461 Query 466 AAEVGGD--AQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDR 521 A EV + +V EI DR AI AVAWAR GD VL+AGKGHETGQ G PFDDR Sbjct 462 ALEVPAEVRGEVREIGDRAAAIEAAVAWARRGDAVLVAGKGHETGQEIAGVKHPFDDR 519 >gi|258654055|ref|YP_003203211.1| UDP-N-acetylmuramyl-tripeptide synthetase [Nakamurella multipartita DSM 44233] gi|258557280|gb|ACV80222.1| UDP-N-acetylmuramyl-tripeptide synthetase [Nakamurella multipartita DSM 44233] Length=533 Score = 430 bits (1105), Expect = 4e-118, Method: Compositional matrix adjust. Identities = 269/497 (55%), Positives = 317/497 (64%), Gaps = 19/497 (3%) Query 45 AALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVL 104 AAL +R +TG+TLRAQDV P DLFAAL GS HGA + G A+ RGA AVL Sbjct 5 AALTGARLERPAPTGERLTGITLRAQDVRPHDLFAALPGSRAHGAGYAGQALERGAAAVL 64 Query 105 TDPAGVAEIAGR--AAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTY 162 TD AG +AG +V +LV PR LG +A +YG PS RL V+G+TGTSGKTTT Y Sbjct 65 TDRAGAELLAGTDLGSVALLVVERPREHLGAIARQLYGDPSRRLAVVGVTGTSGKTTTCY 124 Query 163 LVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVS 222 L+EA L A G + +IGT+ R+ G PSALTTPEAP LQA+LA MVERGV V MEVS Sbjct 125 LLEAALAADGSRSAVIGTVQTRIDGQITPSALTTPEAPDLQALLAVMVERGVGAVAMEVS 184 Query 223 SHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCID 282 SHAL+LGRV GTRFAVGAFTNLS+DHLDFH M DYF AKA LFD RA V+ +D Sbjct 185 SHALSLGRVSGTRFAVGAFTNLSQDHLDFHHDMEDYFRAKAMLFDG----RAGAHVIDVD 240 Query 283 DDAGRAMAARAADAITVSAADRP--AHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLP 340 + G +AA +A+TVS DRP A W V G Q P + + +P Sbjct 241 TEYGARLAAEHPEALTVS--DRPGAADWSVEMVTLAANGVQHVVLSGPGKRQVTLDLAIP 298 Query 341 GRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEAL 400 G +NV N VALA +D +G +QA L + VPGR+E++D GQ FLA+VDYAHKP A+ Sbjct 299 GAFNVGNAAVALACVDALGRDVQQAADALATVVVPGRMERVDAGQDFLAVVDYAHKPGAV 358 Query 401 RSVLTT----LAHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPT 456 +VL LA P L VV GAGGDRD GKR MG +A AD+++VTDDNPR E P Sbjct 359 AAVLDAIGQGLAGP---LIVVLGAGGDRDTGKRPMMGAESAARADVLIVTDDNPRSERPA 415 Query 457 AIRREILAGAAEVGG--DAQVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGR 514 IR ++LAGAA V QV+EI DRR AIR AV A G V+IAGKGHE GQ G Sbjct 416 DIRAQVLAGAAPVADRRPCQVLEIGDRRAAIRRAVQLAGTGGAVVIAGKGHEQGQEIDGV 475 Query 515 VRPFDDRVELAAALEAL 531 V PF DR EL AAL AL Sbjct 476 VHPFSDRDELRAALVAL 492 >gi|302528474|ref|ZP_07280816.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Streptomyces sp. AA4] gi|302437369|gb|EFL09185.1| UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase [Streptomyces sp. AA4] Length=519 Score = 428 bits (1100), Expect = 1e-117, Method: Compositional matrix adjust. Identities = 282/500 (57%), Positives = 337/500 (68%), Gaps = 14/500 (2%) Query 34 VRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVG 93 V LA L + GA L A R D TVTG TLRAQ V PGDLFA L G+ HGA Sbjct 21 VPLATLLARAGARLI---ADRPEAADLTVTGTTLRAQHVLPGDLFAGLPGARAHGADFSD 77 Query 94 DAIARGAVAVLTDPAGVAEIAGR-AAVPVLVHPAPRGVLGGLAATVYGHPSERLTVIGIT 152 A+A GA AVLTDP+G A R A VPVLVHP PR LG +AA +YG PS L+V+G+T Sbjct 78 QALAAGAAAVLTDPSGADRPALRDAPVPVLVHPDPRAALGEIAAWIYGEPSLHLSVLGVT 137 Query 153 GTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVER 212 GTSGKTTT+YLV++GLRAAGR GLIGT+ R+ G L S TTPEAP LQA+LA M+ER Sbjct 138 GTSGKTTTSYLVDSGLRAAGRTTGLIGTVETRIAGERLASGFTTPEAPDLQALLAVMLER 197 Query 213 GVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSAL 272 GV V MEVSSHALALGRV+GTRFAVGAFTNLS+DHLDFH M +YF AK+ LFD Sbjct 198 GVTHVPMEVSSHALALGRVNGTRFAVGAFTNLSQDHLDFHKDMEEYFAAKSLLFDG---- 253 Query 273 RARTAVVCIDDDAGRAMAARAADAITVSA-ADRPAHWRATDVAPTDAGGQQFTAIDPAGV 331 R+ T VV +D G+A+ +++ A AD A WRA D+ T AG Q FT + P G+ Sbjct 254 RSTTEVVVVDSAWGQALLTPQTVTVSIEAGAD--ALWRAADIEATPAGEQTFTLLGPDGL 311 Query 332 GHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALV 391 I LPG +NVAN ++A AIL + G+ + V GL + VPGR+E++ GQ F A+V Sbjct 312 SRAAKIPLPGTFNVANAVLAAAILASAGIDADDIVAGLAAVEVPGRMERVYLGQEFTAVV 371 Query 392 DYAHKPEALRSVLTTL-AHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNP 450 DYAHKP A+ L L A + R+ V G GGDRD KR MG A + +DL++VTDDNP Sbjct 372 DYAHKPAAVAQGLDALRARTEGRIITVLGCGGDRDTAKRPMMGEAAVRRSDLLIVTDDNP 431 Query 451 RDEDPTAIRREILAGAAEVGGDA--QVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETG 508 R EDP AIR +LAGA VG A +V+EIADRR+AI HAV+ A PGD+VLIAGKGHETG Sbjct 432 RSEDPAAIRAAMLAGARAVGPAAGGEVLEIADRREAIAHAVSLAGPGDIVLIAGKGHETG 491 Query 509 QRGGGRVRPFDDRVELAAAL 528 Q G V PF DR EL AA+ Sbjct 492 QEAQGVVHPFSDRDELEAAI 511 >gi|296140347|ref|YP_003647590.1| UDP-N-acetylmuramyl-tripeptide synthetase [Tsukamurella paurometabola DSM 20162] gi|296028481|gb|ADG79251.1| UDP-N-acetylmuramyl-tripeptide synthetase [Tsukamurella paurometabola DSM 20162] Length=522 Score = 424 bits (1091), Expect = 2e-116, Method: Compositional matrix adjust. Identities = 282/517 (55%), Positives = 339/517 (66%), Gaps = 10/517 (1%) Query 27 RPNAVVGVRLAALADQVGAALAEGPAQRAVTEDRTVTGVTLRAQDVSPGDLFAALTGSTT 86 RP G L +A QV ++ PA E R +G T+RAQD PGDLF + G++T Sbjct 8 RPAHPRGATLTEIAAQVPGVISV-PASSDSGEVR-CSGATIRAQDARPGDLFCGVPGTST 65 Query 87 HGARHVGDAIARGAVAVLTDPAGVAEIAGRAA-VPVLVHPAPRGVLGGLAATVYGHPSER 145 HGAR +A+A GAVAVLTD AG A +A VPVL+H PR VLG AA +YG PS + Sbjct 66 HGARFAAEAVAAGAVAVLTDSAGAAVLAEAGVDVPVLLHDDPRSVLGPAAAVIYGAPSTK 125 Query 146 LTVIGITGTSGKTTTTYLVEAGLRAAGRVAGLIGTIGIRVGGADLPSALTTPEAPTLQAM 205 +T++GITGTSGKTTT++LVEA L A GLIGT+G R+ G D+P++LTTPE LQ + Sbjct 126 MTLVGITGTSGKTTTSFLVEAALGATQATTGLIGTVGTRIAGVDVPTSLTTPEGTALQGL 185 Query 206 LAAMVERGVDTVVMEVSSHALALGRVDGTRFAVGAFTNLSRDHLDFHPSMADYFEAKASL 265 A+MVE+GV + VMEVSSHALA RV GTRFAVGAFTNLS+DHLD+HP+M DYF AKA L Sbjct 186 FASMVEQGVTSAVMEVSSHALAQNRVGGTRFAVGAFTNLSQDHLDYHPTMEDYFAAKALL 245 Query 266 FDPDSALR---ARTAVVCIDDDAGRAMAARAADA---ITVSAADRPAHWRATDVAPTDAG 319 F PD + AV+C+DD+ G MA DA + A PA W A V+ G Sbjct 246 FVPDESGDGPVCEQAVICVDDEWGNRMADLRRDAGLPLVTVATTGPADWTAGAVSAHADG 305 Query 320 GQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAILDTVGVSPEQAVPGLREIRVPGRLE 379 Q+FT P G + LPG YNVAN +AL + GV AV G+ + VPGR++ Sbjct 306 TQRFTLTGPGGQSFSATVGLPGAYNVANAALALVVAHEAGVPLADAVRGIGAVAVPGRVQ 365 Query 380 QIDRGQGFLALVDYAHKPEALRSVLTTL-AHPDRRLAVVFGAGGDRDPGKRAPMGRIAAQ 438 +IDRGQ FLA+VDYAHKP AL +V+ TL R+AVV GAGGDRD GKR MG +AA+ Sbjct 366 RIDRGQDFLAVVDYAHKPAALDAVIATLRGQTAGRIAVVVGAGGDRDRGKRPLMGEVAAR 425 Query 439 LADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDAQVVEIADRRDAIRHAVAWARPGDVV 498 A+LV+VTDDNPR EDP AIR + AGA V G +V EI DRR AI AV WAR GDVV Sbjct 426 AAELVIVTDDNPRTEDPAAIRAAVRAGAEAVPGGGEVREIGDRRAAITEAVDWARTGDVV 485 Query 499 LIAGKGHETGQRGGGRVRPFDDRVELAAALEALERRA 535 LIAGKGHE GQ G PFDDR ELAAAL+ RA Sbjct 486 LIAGKGHEAGQEINGVKHPFDDRDELAAALDTRGERA 522 >gi|337291125|ref|YP_004630146.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase [Corynebacterium ulcerans BR-AD22] gi|334699431|gb|AEG84227.1| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase [Corynebacterium ulcerans BR-AD22] Length=503 Score = 422 bits (1084), Expect = 9e-116, Method: Compositional matrix adjust. Identities = 247/482 (52%), Positives = 326/482 (68%), Gaps = 8/482 (1%) Query 58 EDRTVTGVTLRAQDVSPGDLFAALTGSTTHGARHVGDAIARGAVAVLTDPAGVAEIAGRA 117 +D + ++L +Q++ G LFAAL G+ +HGA + A A A+LTD AG A + Sbjct 26 KDIVIEDISLDSQELPQGGLFAALPGTRSHGAVY---AQGTQAAAILTDAAGAAILHESG 82 Query 118 AV-PVLVHPAPRGVLGGLAATVYGHPSERLTVIGITGTSGKTTTTYLVEAGLRAAGRVAG 176 P L+ R +LG ++A +YGHPSE L VIGITGTSGKTTT+Y++EAGL AG+ G Sbjct 83 DTRPRLLVENVRDILGAVSAEIYGHPSESLQVIGITGTSGKTTTSYMLEAGLINAGKSVG 142 Query 177 LIGTIGIRVGGADLPSALTTPEAPTLQAMLAAMVERGVDTVVMEVSSHALALGRVDGTRF 236 LIGT G R+ G +P+ LTTPEAP LQ + A M+++GV VVMEVSSHAL+LGRV T F Sbjct 143 LIGTTGTRINGVKIPTKLTTPEAPMLQKLFAQMLDQGVTHVVMEVSSHALSLGRVSATHF 202 Query 237 AVGAFTNLSRDHLDFHPSMADYFEAKASLFDPDSALRARTAVVCIDDDAGRAMAAR-AAD 295 A FTNLS+DHLDFHP+M +YFEAKA LFDP SA+ AVVCIDD G M R +AD Sbjct 203 AAAGFTNLSQDHLDFHPTMEEYFEAKAVLFDPASAVHTNKAVVCIDDPWGLQMLERSSAD 262 Query 296 AITVS-AADRPAHWRATDVAPTDAGGQQFTAIDPAGVGHHIGIRLPGRYNVANCLVALAI 354 A++VS +A++ A + + + AGGQ+F + + + +PG +NVAN +A+ + Sbjct 263 ALSVSTSAEKQADFAVSGLTVDAAGGQRFV-VTHKDRNIDVDLPIPGAFNVANAALAVGL 321 Query 355 LDTVGVSPEQAVPGLREIRVPGRLEQIDRGQGFLALVDYAHKPEALRSVLTTL-AHPDRR 413 ++G+ ++ V GL + VPGR+E+++RGQ FLA+VDYAHKP A+ +VL + R Sbjct 322 ASSIGIDLDRFVAGLTAVSVPGRMERVNRGQDFLAIVDYAHKPAAVAAVLDAVRRQAAGR 381 Query 414 LAVVFGAGGDRDPGKRAPMGRIAAQLADLVVVTDDNPRDEDPTAIRREILAGAAEVGGDA 473 +A+V GAGGDRD GKR+ MG +A+ ADLV+VTDDNPR EDP IR +L GA E A Sbjct 382 VAIVVGAGGDRDKGKRSIMGEESARRADLVIVTDDNPRSEDPALIREAVLRGAREAATTA 441 Query 474 QVVEIADRRDAIRHAVAWARPGDVVLIAGKGHETGQRGGGRVRPFDDRVELAAALEALER 533 ++ EI DRR+AI+ AVAWARP D V+IAGKGHE GQ G FDDR ELAAALE + Sbjct 442 EIREIGDRREAIKQAVAWARPTDAVIIAGKGHEVGQLIQGINHHFDDREELAAALEEIRN 501 Query 534 RA 535 + Sbjct 502 NS 503 Lambda K H 0.319 0.135 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1174515528420 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40