BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2160c

Length=113
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609297|ref|NP_216676.1|  hypothetical protein Rv2160c [Mycob...   218    3e-55
gi|31793340|ref|NP_855833.1|  hypothetical protein Mb2184c [Mycob...   199    1e-49
gi|326903777|gb|EGE50710.1|  hypothetical protein TBPG_01659 [Myc...   199    1e-49
gi|340627168|ref|YP_004745620.1|  putative TetR family transcript...   176    7e-43
gi|167966687|ref|ZP_02548964.1|  hypothetical protein MtubH3_0089...   145    3e-33
gi|289758282|ref|ZP_06517660.1|  conserved hypothetical protein [...   118    2e-25
gi|37520054|ref|NP_923431.1|  TetR family transcriptional regulat...  86.3    1e-15
gi|332528869|ref|ZP_08404843.1|  TetR family transcriptional regu...  71.2    4e-11
gi|171060703|ref|YP_001793052.1|  TetR family transcriptional reg...  66.6    1e-09
gi|158337307|ref|YP_001518482.1|  TetR family transcriptional reg...  66.6    1e-09
gi|89902285|ref|YP_524756.1|  TetR family transcriptional regulat...  66.2    2e-09
gi|153003888|ref|YP_001378213.1|  TetR family transcriptional reg...  65.9    2e-09
gi|226359583|ref|YP_002777361.1|  TetR family transcriptional reg...  65.1    3e-09
gi|302527892|ref|ZP_07280234.1|  conserved hypothetical protein [...  63.9    7e-09
gi|296127957|ref|YP_003635207.1|  TetR family transcriptional reg...  63.9    7e-09
gi|260219948|emb|CBA26996.1|  hypothetical protein Csp_A00070 [Cu...  63.9    8e-09
gi|345002979|ref|YP_004805833.1|  TetR family transcriptional reg...  62.8    2e-08
gi|320007627|gb|ADW02477.1|  regulatory protein TetR [Streptomyce...  62.0    2e-08
gi|239813818|ref|YP_002942728.1|  TetR family transcriptional reg...  60.1    1e-07
gi|29827759|ref|NP_822393.1|  TetR family transcriptional regulat...  60.1    1e-07
gi|221065049|ref|ZP_03541154.1|  transcriptional regulator, TetR ...  59.7    1e-07
gi|241664654|ref|YP_002983014.1|  TetR family transcriptional reg...  59.7    1e-07
gi|187930486|ref|YP_001900973.1|  TetR family transcriptional reg...  59.7    1e-07
gi|299532696|ref|ZP_07046084.1|  transcriptional regulator, TetR ...  59.3    2e-07
gi|264680339|ref|YP_003280249.1|  TetR family transcriptional reg...  59.3    2e-07
gi|337278543|ref|YP_004618014.1|  TetR family transcriptional reg...  58.9    2e-07
gi|162451486|ref|YP_001613853.1|  TetR family transcriptional reg...  58.9    2e-07
gi|91789798|ref|YP_550750.1|  TetR family transcriptional regulat...  58.9    3e-07
gi|121593018|ref|YP_984914.1|  TetR family transcriptional regula...  58.5    3e-07
gi|222109786|ref|YP_002552050.1|  TetR family transcriptional reg...  58.5    3e-07
gi|121606367|ref|YP_983696.1|  TetR family transcriptional regula...  58.2    4e-07
gi|291302534|ref|YP_003513812.1|  TetR family transcriptional reg...  58.2    4e-07
gi|337765507|emb|CCB74216.1|  putative TetR-family transcriptiona...  58.2    4e-07
gi|160896783|ref|YP_001562365.1|  TetR family transcriptional reg...  57.8    5e-07
gi|333916771|ref|YP_004490503.1|  regulatory protein TetR [Delfti...  57.8    5e-07
gi|88855890|ref|ZP_01130552.1|  putative transcriptional regulato...  57.4    7e-07
gi|319791523|ref|YP_004153163.1|  TetR family transcriptional reg...  57.0    8e-07
gi|319761393|ref|YP_004125330.1|  regulatory protein tetr [Alicyc...  56.6    1e-06
gi|119715467|ref|YP_922432.1|  TetR family transcriptional regula...  56.6    1e-06
gi|330823263|ref|YP_004386566.1|  regulatory protein TetR [Alicyc...  56.6    1e-06
gi|197123598|ref|YP_002135549.1|  TetR family transcriptional reg...  56.2    2e-06
gi|302870404|ref|YP_003839041.1|  regulatory protein TetR [Microm...  55.8    2e-06
gi|220918390|ref|YP_002493694.1|  TetR family transcriptional reg...  55.8    2e-06
gi|121608206|ref|YP_996013.1|  TetR family transcriptional regula...  55.5    3e-06
gi|326318790|ref|YP_004236462.1|  regulatory protein TetR [Acidov...  55.5    3e-06
gi|120612727|ref|YP_972405.1|  TetR family transcriptional regula...  55.1    3e-06
gi|284030443|ref|YP_003380374.1|  TetR family transcriptional reg...  55.1    3e-06
gi|284029822|ref|YP_003379753.1|  TetR family transcriptional reg...  53.5    9e-06
gi|291297595|ref|YP_003508873.1|  TetR family transcriptional reg...  53.1    1e-05
gi|317125611|ref|YP_004099723.1|  TetR transcriptional regulator ...  53.1    1e-05


>gi|15609297|ref|NP_216676.1| hypothetical protein Rv2160c [Mycobacterium tuberculosis H37Rv]
 gi|15841652|ref|NP_336689.1| hypothetical protein MT2218.1 [Mycobacterium tuberculosis CDC1551]
 gi|148661976|ref|YP_001283499.1| hypothetical protein MRA_2175 [Mycobacterium tuberculosis H37Ra]
 13 more sequence titles
 
gi|253798775|ref|YP_003031776.1| hypothetical protein TBMG_01821 [Mycobacterium tuberculosis KZN 
1435]
 gi|254232318|ref|ZP_04925645.1| conserved hypothetical protein [Mycobacterium tuberculosis C]
 gi|254364962|ref|ZP_04981008.1| conserved hypothetical protein [Mycobacterium tuberculosis str. 
Haarlem]
 gi|308374508|ref|ZP_07436320.2| hypothetical protein TMFG_01122 [Mycobacterium tuberculosis SUMu006]
 gi|2104318|emb|CAB08667.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium tuberculosis H37Rv]
 gi|13881904|gb|AAK46503.1| hypothetical protein MT2218.1 [Mycobacterium tuberculosis CDC1551]
 gi|124601377|gb|EAY60387.1| conserved hypothetical protein [Mycobacterium tuberculosis C]
 gi|134150476|gb|EBA42521.1| conserved hypothetical protein [Mycobacterium tuberculosis str. 
Haarlem]
 gi|148506128|gb|ABQ73937.1| hypothetical protein MRA_2175 [Mycobacterium tuberculosis H37Ra]
 gi|253320278|gb|ACT24881.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 
1435]
 gi|308341708|gb|EFP30559.1| hypothetical protein TMFG_01122 [Mycobacterium tuberculosis SUMu006]
 gi|328458538|gb|AEB03961.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 
4207]
 gi|344219984|gb|AEN00615.1| hypothetical protein MTCTRI2_2197 [Mycobacterium tuberculosis 
CTRI-2]
Length=113

 Score =  218 bits (554),  Expect = 3e-55, Method: Compositional matrix adjust.
 Identities = 112/113 (99%), Positives = 113/113 (100%), Gaps = 0/113 (0%)

Query  1    VGRIPGTRRAGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRAD  60
            +GRIPGTRRAGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRAD
Sbjct  1    MGRIPGTRRAGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRAD  60

Query  61   IEVRQLAFELHAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES  113
            IEVRQLAFELHAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES
Sbjct  61   IEVRQLAFELHAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES  113


>gi|31793340|ref|NP_855833.1| hypothetical protein Mb2184c [Mycobacterium bovis AF2122/97]
 gi|121638042|ref|YP_978266.1| hypothetical protein BCG_2177c [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|224990536|ref|YP_002645223.1| hypothetical protein JTY_2171 [Mycobacterium bovis BCG str. Tokyo 
172]
 23 more sequence titles
 
gi|289443666|ref|ZP_06433410.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289447788|ref|ZP_06437532.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
 gi|289570277|ref|ZP_06450504.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
 gi|289574843|ref|ZP_06455070.1| conserved hypothetical protein [Mycobacterium tuberculosis K85]
 gi|289745434|ref|ZP_06504812.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289750757|ref|ZP_06510135.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
 gi|289754270|ref|ZP_06513648.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054]
 gi|294993546|ref|ZP_06799237.1| hypothetical protein Mtub2_03314 [Mycobacterium tuberculosis 
210]
 gi|298525654|ref|ZP_07013063.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|31618932|emb|CAD97037.1| CONSERVED HYPOTHETICAL PROTEIN [Mycobacterium bovis AF2122/97]
 gi|121493690|emb|CAL72165.1| Conserved hypothetical protein [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|224773649|dbj|BAH26455.1| hypothetical protein JTY_2171 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|289416585|gb|EFD13825.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289420746|gb|EFD17947.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
 gi|289539274|gb|EFD43852.1| conserved hypothetical protein [Mycobacterium tuberculosis K85]
 gi|289544031|gb|EFD47679.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
 gi|289685962|gb|EFD53450.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|289691344|gb|EFD58773.1| conserved hypothetical protein [Mycobacterium tuberculosis T92]
 gi|289694857|gb|EFD62286.1| conserved hypothetical protein [Mycobacterium tuberculosis EAS054]
 gi|298495448|gb|EFI30742.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|339295077|gb|AEJ47188.1| hypothetical protein CCDC5079_1998 [Mycobacterium tuberculosis 
CCDC5079]
 gi|339298698|gb|AEJ50808.1| hypothetical protein CCDC5180_1971 [Mycobacterium tuberculosis 
CCDC5180]
 gi|341602080|emb|CCC64754.1| conserved hypothetical protein [Mycobacterium bovis BCG str. 
Moreau RDJ]
Length=206

 Score =  199 bits (507),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 102/103 (99%), Positives = 102/103 (99%), Gaps = 0/103 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIE RQLAFEL
Sbjct  104  GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEARQLAFEL  163

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES  113
            HAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES
Sbjct  164  HAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES  206


>gi|326903777|gb|EGE50710.1| hypothetical protein TBPG_01659 [Mycobacterium tuberculosis W-148]
Length=206

 Score =  199 bits (506),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 102/103 (99%), Positives = 102/103 (99%), Gaps = 0/103 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIE RQLAFEL
Sbjct  104  GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEARQLAFEL  163

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES  113
            HAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES
Sbjct  164  HAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES  206


>gi|340627168|ref|YP_004745620.1| putative TetR family transcriptional regulator [Mycobacterium 
canettii CIPT 140010059]
 gi|340005358|emb|CCC44516.1| putative TetR family transcriptional regulator [Mycobacterium 
canettii CIPT 140010059]
Length=206

 Score =  176 bits (447),  Expect = 7e-43, Method: Compositional matrix adjust.
 Identities = 97/103 (95%), Positives = 99/103 (97%), Gaps = 0/103 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCFFAAAAADVDSQPGPVRDRIA TGRAGIAAIT DVETAQR G+IRADIE RQLAFEL
Sbjct  104  GGCFFAAAAADVDSQPGPVRDRIAETGRAGIAAITTDVETAQRLGQIRADIEARQLAFEL  163

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVES  113
            HAYAMEANWALLLLDDDGAG+RARTAIDAALARVGTTQEGVES
Sbjct  164  HAYAMEANWALLLLDDDGAGDRARTAIDAALARVGTTQEGVES  206


>gi|167966687|ref|ZP_02548964.1| hypothetical protein MtubH3_00893 [Mycobacterium tuberculosis 
H37Ra]
Length=429

 Score =  145 bits (365),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 75/76 (99%), Positives = 76/76 (100%), Gaps = 0/76 (0%)

Query  29   VRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELHAYAMEANWALLLLDDDG  88
            +RDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELHAYAMEANWALLLLDDDG
Sbjct  1    MRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELHAYAMEANWALLLLDDDG  60

Query  89   AGERARTAIDAALARV  104
            AGERARTAIDAALARV
Sbjct  61   AGERARTAIDAALARV  76


>gi|289758282|ref|ZP_06517660.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
 gi|289713846|gb|EFD77858.1| conserved hypothetical protein [Mycobacterium tuberculosis T85]
Length=63

 Score =  118 bits (296),  Expect = 2e-25, Method: Compositional matrix adjust.
 Identities = 60/61 (99%), Positives = 60/61 (99%), Gaps = 0/61 (0%)

Query  53   RRGEIRADIEVRQLAFELHAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVE  112
            RRGEIRADIE RQLAFELHAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVE
Sbjct  3    RRGEIRADIEARQLAFELHAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEGVE  62

Query  113  S  113
            S
Sbjct  63   S  63


>gi|37520054|ref|NP_923431.1| TetR family transcriptional regulatory protein [Gloeobacter violaceus 
PCC 7421]
 gi|35211046|dbj|BAC88426.1| TetR family transcriptional regulatory protein [Gloeobacter violaceus 
PCC 7421]
Length=218

 Score = 86.3 bits (212),  Expect = 1e-15, Method: Compositional matrix adjust.
 Identities = 44/95 (47%), Positives = 59/95 (63%), Gaps = 0/95 (0%)

Query  10   AGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFE  69
            AGGCFF A + + DS+PGPVR+++A      +  +   +  AQ  GE+  DIE  QLAFE
Sbjct  115  AGGCFFMAISTEFDSRPGPVREKLALIMGYWLRNLERRIREAQELGELPTDIEPAQLAFE  174

Query  70   LHAYAMEANWALLLLDDDGAGERARTAIDAALARV  104
            +HA  M ANWA  L DD  A +RAR AI   +A++
Sbjct  175  IHALGMGANWAFQLFDDPQALQRARLAIRERVAQL  209


>gi|332528869|ref|ZP_08404843.1| TetR family transcriptional regulator [Hylemonella gracilis ATCC 
19624]
 gi|332041728|gb|EGI78080.1| TetR family transcriptional regulator [Hylemonella gracilis ATCC 
19624]
Length=224

 Score = 71.2 bits (173),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 35/93 (38%), Positives = 54/93 (59%), Gaps = 0/93 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
             GC F + A D D +PGPVRD +A++ R  +AA+      A+  G++ AD +VRQ+ FE+
Sbjct  126  SGCIFISGAIDFDDRPGPVRDALASSVRVWLAAVERAATLAKEEGQLVADADVRQICFEI  185

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAALAR  103
            H   +  ++    L   G+ ERA+ A +  LAR
Sbjct  186  HGLILSVHYEARFLQTPGSIERAQRAFEQILAR  218


>gi|171060703|ref|YP_001793052.1| TetR family transcriptional regulator [Leptothrix cholodnii SP-6]
 gi|170778148|gb|ACB36287.1| transcriptional regulator, TetR family [Leptothrix cholodnii 
SP-6]
Length=219

 Score = 66.6 bits (161),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 35/92 (39%), Positives = 52/92 (57%), Gaps = 0/92 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D +PGPVRD +A   R   AA+   +E A+  G++R D + RQ+AFE+H
Sbjct  118  GCIYISGAVEFDDRPGPVRDALADMVRTWHAALHRAIEIAREVGDLRPDTDARQMAFEMH  177

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALAR  103
               +  +     L + GA ERAR   +  LAR
Sbjct  178  GLILALHHDARFLREPGAVERARRGFEHMLAR  209


>gi|158337307|ref|YP_001518482.1| TetR family transcriptional regulator [Acaryochloris marina MBIC11017]
 gi|158307548|gb|ABW29165.1| transcriptional regulator, TetR family [Acaryochloris marina 
MBIC11017]
Length=211

 Score = 66.6 bits (161),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 38/99 (39%), Positives = 52/99 (53%), Gaps = 0/99 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCFFAA + + +S+PGP+RDR+A             V  AQ  G+I + ++  QLA+EL
Sbjct  109  GGCFFAATSTEFNSRPGPIRDRLADIMAERQQTFARLVARAQEVGDIHSSVDPVQLAYEL  168

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQE  109
                  ANWA  L  D     R++TA+   L  V T  E
Sbjct  169  DMLLFGANWAFQLYGDGDVIVRSQTAMRHRLKSVCTHPE  207


>gi|89902285|ref|YP_524756.1| TetR family transcriptional regulator [Rhodoferax ferrireducens 
T118]
 gi|89347022|gb|ABD71225.1| transcriptional regulator, TetR family [Rhodoferax ferrireducens 
T118]
Length=236

 Score = 66.2 bits (160),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 33/99 (34%), Positives = 54/99 (55%), Gaps = 0/99 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC F + A + D +PGPVRD +A++ +  +AA+   V  A++ G++  D +  Q+AFE+H
Sbjct  123  GCIFISGAVEFDDRPGPVRDALASSVKTWLAAMYRAVVQAKQEGQLHEDADEEQMAFEIH  182

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQEG  110
               +  ++    L +  A  RA T  D  L R G +  G
Sbjct  183  GLILALHYEARFLQNPAAIGRAHTGFDNILKRYGKSAAG  221


>gi|153003888|ref|YP_001378213.1| TetR family transcriptional regulator [Anaeromyxobacter sp. Fw109-5]
 gi|152027461|gb|ABS25229.1| transcriptional regulator, TetR family [Anaeromyxobacter sp. 
Fw109-5]
Length=198

 Score = 65.9 bits (159),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 37/96 (39%), Positives = 52/96 (55%), Gaps = 0/96 (0%)

Query  7    TRRAGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQL  66
             R+ GGC F AAAA++D +PG  RD +    R  ++ ++  V   Q  G  RAD++  QL
Sbjct  97   VRQPGGCVFVAAAAELDDRPGAARDLLVEIQRQWLSTLSRIVRRGQELGHFRADVDPAQL  156

Query  67   AFELHAYAMEANWALLLLDDDGAGERARTAIDAALA  102
            AFE+H   +  N    LL D  + ERA  A +  LA
Sbjct  157  AFEIHGIGLAWNSHSRLLRDPRSRERAEAAFERLLA  192


>gi|226359583|ref|YP_002777361.1| TetR family transcriptional regulator [Rhodococcus opacus B4]
 gi|226238068|dbj|BAH48416.1| putative TetR family transcriptional regulator [Rhodococcus opacus 
B4]
Length=212

 Score = 65.1 bits (157),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 39/100 (39%), Positives = 52/100 (52%), Gaps = 1/100 (1%)

Query  11   GGCFFAAAAADVDSQ-PGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFE  69
            GGCFFAAA A+ D + PGPVRD +    R  +  +      AQ+ GE+  D +  QLAFE
Sbjct  107  GGCFFAAAMAEFDGKTPGPVRDAVTECQRQWMETLAQSAHEAQQSGELCIDTDPDQLAFE  166

Query  70   LHAYAMEANWALLLLDDDGAGERARTAIDAALARVGTTQE  109
            L    + AN    L  D    +RAR A+   L+   +T E
Sbjct  167  LEGTLLAANSYFHLFADTRYLDRARLAVRTRLSSGASTPE  206


>gi|302527892|ref|ZP_07280234.1| conserved hypothetical protein [Streptomyces sp. AA4]
 gi|302436787|gb|EFL08603.1| conserved hypothetical protein [Streptomyces sp. AA4]
Length=215

 Score = 63.9 bits (154),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 31/68 (46%), Positives = 41/68 (61%), Gaps = 0/68 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCFF   A + DS+PGP+RD IAA  + G   +   +  A  +GE+RAD +V +LAFEL
Sbjct  109  GGCFFTPVAHEFDSRPGPIRDAIAALIQEGNDVLAQQIRVAVAKGELRADTDVAELAFEL  168

Query  71   HAYAMEAN  78
                  AN
Sbjct  169  QGLLFAAN  176


>gi|296127957|ref|YP_003635207.1| TetR family transcriptional regulator [Cellulomonas flavigena 
DSM 20109]
 gi|296019772|gb|ADG73008.1| transcriptional regulator, TetR family [Cellulomonas flavigena 
DSM 20109]
Length=207

 Score = 63.9 bits (154),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 39/100 (39%), Positives = 52/100 (52%), Gaps = 0/100 (0%)

Query  8    RRAGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLA  67
            RR GGC F  A+ ++D Q GPVRDR+    R    +I   V      G+ RAD +  Q A
Sbjct  102  RRPGGCLFVKASTELDEQDGPVRDRLRDQHRQLADSIARIVAGGVTEGQFRADTDTAQFA  161

Query  68   FELHAYAMEANWALLLLDDDGAGERARTAIDAALARVGTT  107
             +LH   +       LL+D  A + ARTAID  LA V ++
Sbjct  162  TDLHGVMLGLYHGHRLLEDPAAEQHARTAIDRLLAAVRSS  201


>gi|260219948|emb|CBA26996.1| hypothetical protein Csp_A00070 [Curvibacter putative symbiont 
of Hydra magnipapillata]
Length=224

 Score = 63.9 bits (154),  Expect = 8e-09, Method: Compositional matrix adjust.
 Identities = 31/96 (33%), Positives = 54/96 (57%), Gaps = 0/96 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC F + A + D +PGPVRD +A++ +  ++A+   V  A++ G +R + + +Q+AFE+H
Sbjct  127  GCIFISGAVEFDDRPGPVRDALASSVQTWLSALYRAVVLAKQCGHLRPEADEQQMAFEIH  186

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALARVGTT  107
               +  ++    L + G+ ERA       LAR   T
Sbjct  187  GLILALHYEARFLKNPGSIERANRGFSNILARYAIT  222


>gi|345002979|ref|YP_004805833.1| TetR family transcriptional regulator [Streptomyces sp. SirexAA-E]
 gi|344318605|gb|AEN13293.1| transcriptional regulator, TetR family [Streptomyces sp. SirexAA-E]
Length=214

 Score = 62.8 bits (151),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 37/87 (43%), Positives = 50/87 (58%), Gaps = 0/87 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCFF A  A+ DS+ G V D +AAT    +  +   +E A+ RGE+ AD +V QLAFEL
Sbjct  110  GGCFFYATIAEFDSRKGKVHDALAATQTGWVTFVEETLEEARVRGELAADTDVSQLAFEL  169

Query  71   HAYAMEANWALLLLDDDGAGERARTAI  97
             A+   AN   +L D+     +A  AI
Sbjct  170  IAFMELANAESVLHDNAPGYAKATKAI  196


>gi|320007627|gb|ADW02477.1| regulatory protein TetR [Streptomyces flavogriseus ATCC 33331]
Length=217

 Score = 62.0 bits (149),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 36/88 (41%), Positives = 51/88 (58%), Gaps = 0/88 (0%)

Query  10   AGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFE  69
            +GGCFF A  A+ DS+ G V D +A+T    +  +   VE A+ RGE+ AD +V QLAFE
Sbjct  109  SGGCFFYATIAEFDSREGKVHDALASTQTGWVTFVEETVEEARVRGELAADTDVSQLAFE  168

Query  70   LHAYAMEANWALLLLDDDGAGERARTAI  97
            L A+   AN   +L  ++    +A  AI
Sbjct  169  LIAFMELANAESVLHSNNPGYTKAARAI  196


>gi|239813818|ref|YP_002942728.1| TetR family transcriptional regulator [Variovorax paradoxus S110]
 gi|239800395|gb|ACS17462.1| transcriptional regulator, TetR family [Variovorax paradoxus 
S110]
Length=233

 Score = 60.1 bits (144),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 32/93 (35%), Positives = 49/93 (53%), Gaps = 0/93 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
             GC + + A++ D +PGPVRD +  +     AA+   +  A+  G +RAD + RQLAFE+
Sbjct  113  SGCIYISGASEFDDRPGPVRDALVESVSIWQAAVLRAIVQAKSEGHLRADADERQLAFEI  172

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAALAR  103
            H   +  ++    L   G+  RA    D  LAR
Sbjct  173  HGLILALHYEARFLQVPGSIGRANVGFDNILAR  205


>gi|29827759|ref|NP_822393.1| TetR family transcriptional regulator [Streptomyces avermitilis 
MA-4680]
 gi|29604860|dbj|BAC68928.1| putative TetR-family transcriptional regulator [Streptomyces 
avermitilis MA-4680]
Length=199

 Score = 60.1 bits (144),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 35/93 (38%), Positives = 51/93 (55%), Gaps = 0/93 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCF  + A++ D +PGPVRD +        A +T ++ TA   G +    +V QLAFEL
Sbjct  107  GGCFLTSVASEFDGRPGPVRDAVLDALSRWTAYVTGELSTAVEAGRLPPLTDVDQLAFEL  166

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAALAR  103
            +   + A+ ++ L  D  A +RAR AI   L R
Sbjct  167  NGVILAADQSIQLHRDPQAPDRARRAIGRLLKR  199


>gi|221065049|ref|ZP_03541154.1| transcriptional regulator, TetR family [Comamonas testosteroni 
KF-1]
 gi|220710072|gb|EED65440.1| transcriptional regulator, TetR family [Comamonas testosteroni 
KF-1]
Length=268

 Score = 59.7 bits (143),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 30/95 (32%), Positives = 51/95 (54%), Gaps = 0/95 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +A +    +AA+   +  +Q  G++RAD +  QL FE+H
Sbjct  169  GCIYISGAVEFDDRTGPVRDALAESVSTWLAAMRRTIVQSQECGDLRADADASQLLFEIH  228

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALARVGT  106
               +  ++    L  +G+ ERA    +  LAR  +
Sbjct  229  GLILALHYEARFLHSEGSIERAHAGFNNILARYAS  263


>gi|241664654|ref|YP_002983014.1| TetR family transcriptional regulator [Ralstonia pickettii 12D]
 gi|309780527|ref|ZP_07675274.1| transcriptional regulator, TetR family [Ralstonia sp. 5_7_47FAA]
 gi|240866681|gb|ACS64342.1| transcriptional regulator, TetR family [Ralstonia pickettii 12D]
 gi|308920682|gb|EFP66332.1| transcriptional regulator, TetR family [Ralstonia sp. 5_7_47FAA]
Length=202

 Score = 59.7 bits (143),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 38/96 (40%), Positives = 55/96 (58%), Gaps = 5/96 (5%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCF  AA+ +  ++PG ++DR+     +  A     +  AQ  GE+RAD++V QL FE+
Sbjct  108  GGCFVCAASYEYRARPGAIQDRVRGHRESVRARFRETITAAQAAGELRADVDVDQLVFEI  167

Query  71   HAYAMEANWALLLLDDDGAGERARTA----IDAALA  102
             ++   AN A  L+ D    ERAR +    IDAALA
Sbjct  168  ESFRSNANVA-FLMGDMAVFERARRSTQARIDAALA  202


>gi|187930486|ref|YP_001900973.1| TetR family transcriptional regulator [Ralstonia pickettii 12J]
 gi|187727376|gb|ACD28541.1| transcriptional regulator, TetR family [Ralstonia pickettii 12J]
Length=202

 Score = 59.7 bits (143),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 38/96 (40%), Positives = 55/96 (58%), Gaps = 5/96 (5%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCF  AA+ +  ++PG ++DR+     +  A     +  AQ  GE+RAD++V QL FE+
Sbjct  108  GGCFVCAASYEYRARPGAIQDRVRGHRESVRARFRETIAAAQAAGELRADVDVDQLVFEI  167

Query  71   HAYAMEANWALLLLDDDGAGERARTA----IDAALA  102
             ++   AN A  L+ D    ERAR +    IDAALA
Sbjct  168  ESFRSNANVA-FLMGDMAVFERARRSTQARIDAALA  202


>gi|299532696|ref|ZP_07046084.1| transcriptional regulator, TetR family protein [Comamonas testosteroni 
S44]
 gi|298719331|gb|EFI60300.1| transcriptional regulator, TetR family protein [Comamonas testosteroni 
S44]
Length=212

 Score = 59.3 bits (142),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 30/95 (32%), Positives = 51/95 (54%), Gaps = 0/95 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +A +    +AA+   +  +Q  G++RAD +  QL FE+H
Sbjct  113  GCIYISGAVEFDDRTGPVRDALAESVGTWLAAMRRTIVQSQECGDLRADADASQLLFEIH  172

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALARVGT  106
               +  ++    L  +G+ ERA    +  LAR  +
Sbjct  173  GLILALHYEARFLHSEGSIERAHAGFNNILARYAS  207


>gi|264680339|ref|YP_003280249.1| TetR family transcriptional regulator [Comamonas testosteroni 
CNB-2]
 gi|262210855|gb|ACY34953.1| transcriptional regulator, TetR family [Comamonas testosteroni 
CNB-2]
Length=264

 Score = 59.3 bits (142),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 30/95 (32%), Positives = 51/95 (54%), Gaps = 0/95 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +A +    +AA+   +  +Q  G++RAD +  QL FE+H
Sbjct  165  GCIYISGAVEFDDRTGPVRDALAESVGTWLAAMRRTIVQSQECGDLRADADASQLLFEIH  224

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALARVGT  106
               +  ++    L  +G+ ERA    +  LAR  +
Sbjct  225  GLILALHYEARFLHSEGSIERAHAGFNNILARYAS  259


>gi|337278543|ref|YP_004618014.1| TetR family transcriptional regulator [Ramlibacter tataouinensis 
TTB310]
 gi|334729619|gb|AEG91995.1| transcriptional regulator, TetR family-like protein [Ramlibacter 
tataouinensis TTB310]
Length=207

 Score = 58.9 bits (141),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 30/95 (32%), Positives = 51/95 (54%), Gaps = 0/95 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +A++  A  AA+   +  A+  G +RA+++  Q+ FE+H
Sbjct  108  GCIYISGAVEFDDRAGPVRDALASSVMAWHAAMKRAIAGAKEEGHLRAEVDEEQMLFEIH  167

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALARVGT  106
               +  ++    L + G+  RA    D  L R GT
Sbjct  168  GLILALHYEARFLKNPGSIARANAGFDNILRRYGT  202


>gi|162451486|ref|YP_001613853.1| TetR family transcriptional regulator [Sorangium cellulosum 'So 
ce 56']
 gi|161162068|emb|CAN93373.1| transcriptional regulator, TetR family [Sorangium cellulosum 
'So ce 56']
Length=202

 Score = 58.9 bits (141),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 32/88 (37%), Positives = 50/88 (57%), Gaps = 0/88 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGC F AAAA++D +PGP RD + A+ +  +A +      A   G  R+D+++ Q AFE 
Sbjct  101  GGCVFHAAAAELDDKPGPARDALVASQKDWLATLATAARIAVEEGHFRSDLDLAQFAFEA  160

Query  71   HAYAMEANWALLLLDDDGAGERARTAID  98
            +A A  ++    L+ D  +  RAR A +
Sbjct  161  YAIASGSHALGRLMRDTASERRARAAFE  188


>gi|91789798|ref|YP_550750.1| TetR family transcriptional regulator [Polaromonas sp. JS666]
 gi|91699023|gb|ABE45852.1| transcriptional regulator, TetR family [Polaromonas sp. JS666]
Length=260

 Score = 58.9 bits (141),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 30/95 (32%), Positives = 49/95 (52%), Gaps = 0/95 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D +PGPVRD +A + R  +AA+   V  A+  G ++ D + +Q+ FE+H
Sbjct  129  GCLYISGAVEFDDRPGPVRDALAGSVRTWLAAMYRAVVQAKEAGHLQRDADEQQMVFEIH  188

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALARVGT  106
               +  ++    L   G+  RA       LAR G 
Sbjct  189  GLILALHYEARFLKSPGSVARANAGFANILARYGN  223


>gi|121593018|ref|YP_984914.1| TetR family transcriptional regulator [Acidovorax sp. JS42]
 gi|120605098|gb|ABM40838.1| transcriptional regulator, TetR family [Acidovorax sp. JS42]
Length=221

 Score = 58.5 bits (140),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 30/92 (33%), Positives = 48/92 (53%), Gaps = 0/92 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +A +     AA+   ++  +  GEIR D+   Q+ FE+H
Sbjct  121  GCIYISGAVEFDDRTGPVRDALANSVMTWQAAMKRAIQQCKECGEIRDDVSEDQMLFEIH  180

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALAR  103
               +  ++    L   G+ +RA T  D  LAR
Sbjct  181  GLILALHYEARFLHTPGSIDRANTGFDNILAR  212


>gi|222109786|ref|YP_002552050.1| TetR family transcriptional regulator [Acidovorax ebreus TPSY]
 gi|221729230|gb|ACM32050.1| transcriptional regulator, TetR family [Acidovorax ebreus TPSY]
Length=221

 Score = 58.5 bits (140),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 30/92 (33%), Positives = 48/92 (53%), Gaps = 0/92 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +A +     AA+   ++  +  GEIR D+   Q+ FE+H
Sbjct  121  GCIYISGAVEFDDRTGPVRDALANSVMTWQAAMKRAIQQCKECGEIRDDVSEDQMLFEIH  180

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALAR  103
               +  ++    L   G+ +RA T  D  LAR
Sbjct  181  GLILALHYEARFLHTPGSIDRANTGFDNILAR  212


>gi|121606367|ref|YP_983696.1| TetR family transcriptional regulator [Polaromonas naphthalenivorans 
CJ2]
 gi|120595336|gb|ABM38775.1| transcriptional regulator, TetR family [Polaromonas naphthalenivorans 
CJ2]
Length=247

 Score = 58.2 bits (139),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 32/96 (34%), Positives = 49/96 (52%), Gaps = 0/96 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D +PGPVRD +  + R  +AA+   V  A   G +  D + +Q+AFE+H
Sbjct  124  GCIYISGAVEFDDRPGPVRDALVDSVRTWLAAMHRAVVQASEAGHLYPDADAQQVAFEIH  183

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALARVGTT  107
               +  ++    L    +  RART     LAR G T
Sbjct  184  GLILALHYEARFLKTPDSIARARTGFANILARYGGT  219


>gi|291302534|ref|YP_003513812.1| TetR family transcriptional regulator [Stackebrandtia nassauensis 
DSM 44728]
 gi|290571754|gb|ADD44719.1| transcriptional regulator, TetR family [Stackebrandtia nassauensis 
DSM 44728]
Length=193

 Score = 58.2 bits (139),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 32/91 (36%), Positives = 48/91 (53%), Gaps = 0/91 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGC F AA+ + D   GP+ DR+ A     +  I+  V T   +G++R D +  Q+A E+
Sbjct  98   GGCLFLAASTEFDDLDGPLHDRMVADEHDLLDTISQVVGTLVSQGDVRPDTDTVQIAQEV  157

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAAL  101
             +  +  NW   +L D  A  RA TA+D  L
Sbjct  158  FSVLLGYNWMSRILSDPTAETRAWTAVDRIL  188


>gi|337765507|emb|CCB74216.1| putative TetR-family transcriptional regulator [Streptomyces 
cattleya NRRL 8057]
Length=201

 Score = 58.2 bits (139),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 37/92 (41%), Positives = 46/92 (50%), Gaps = 1/92 (1%)

Query  11   GGCFFAAAAADVDSQP-GPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFE  69
            GGC F  A  + D +  GPVRD +A   R     +  D+  A R GE+  D + RQLAFE
Sbjct  109  GGCLFTTAVVEFDGRDDGPVRDAVARLFRTWRRRLIVDLRIAVRAGELPPDTDPRQLAFE  168

Query  70   LHAYAMEANWALLLLDDDGAGERARTAIDAAL  101
            L    M  N A+ LL D  A  R R A+   L
Sbjct  169  LIGLYMGLNQAIQLLRDPQAPTRTRKALTRLL  200


>gi|160896783|ref|YP_001562365.1| TetR family transcriptional regulator [Delftia acidovorans SPH-1]
 gi|160362367|gb|ABX33980.1| transcriptional regulator, TetR family [Delftia acidovorans SPH-1]
Length=235

 Score = 57.8 bits (138),  Expect = 5e-07, Method: Compositional matrix adjust.
 Identities = 28/96 (30%), Positives = 53/96 (56%), Gaps = 0/96 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
             GC + + A + D + GPVRD + A+ +   AA+   +   +  G++RAD++  QL FE+
Sbjct  138  SGCIYISGAVEFDDRTGPVRDALTASVQTWHAAMRRTIVQCRESGDLRADLDENQLLFEI  197

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAALARVGT  106
            H   +  ++    L ++G+ +RA    ++ LAR  +
Sbjct  198  HGLILALHYEARFLRNEGSMQRAIDGFESILARYAS  233


>gi|333916771|ref|YP_004490503.1| regulatory protein TetR [Delftia sp. Cs1-4]
 gi|333746971|gb|AEF92148.1| regulatory protein TetR [Delftia sp. Cs1-4]
Length=235

 Score = 57.8 bits (138),  Expect = 5e-07, Method: Compositional matrix adjust.
 Identities = 28/96 (30%), Positives = 53/96 (56%), Gaps = 0/96 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
             GC + + A + D + GPVRD + A+ +   AA+   +   +  G++RAD++  QL FE+
Sbjct  138  SGCIYISGAVEFDDRTGPVRDALTASVQTWHAAMRRTIVQCRESGDLRADLDENQLLFEI  197

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAALARVGT  106
            H   +  ++    L ++G+ +RA    ++ LAR  +
Sbjct  198  HGLILALHYEARFLRNEGSMQRAIDGFESILARYAS  233


>gi|88855890|ref|ZP_01130552.1| putative transcriptional regulator [marine actinobacterium PHSC20C1]
 gi|88814757|gb|EAR24617.1| putative transcriptional regulator [marine actinobacterium PHSC20C1]
Length=219

 Score = 57.4 bits (137),  Expect = 7e-07, Method: Compositional matrix adjust.
 Identities = 36/87 (42%), Positives = 46/87 (53%), Gaps = 0/87 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCFF A A D DS+PG VRD +  +       I A +  A+   ++    +  QLAFE+
Sbjct  108  GGCFFLACATDFDSKPGLVRDALRHSIAQYEDYILAQITAAKLADQLPRLDDPEQLAFEI  167

Query  71   HAYAMEANWALLLLDDDGAGERARTAI  97
             AY  EAN+A LL D      RA  AI
Sbjct  168  RAYYAEANYASLLHDSREPYRRAEHAI  194


>gi|319791523|ref|YP_004153163.1| TetR family transcriptional regulator [Variovorax paradoxus EPS]
 gi|315593986|gb|ADU35052.1| regulatory protein TetR [Variovorax paradoxus EPS]
Length=231

 Score = 57.0 bits (136),  Expect = 8e-07, Method: Compositional matrix adjust.
 Identities = 30/92 (33%), Positives = 49/92 (54%), Gaps = 0/92 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A++ D +PGPVRD +  +     AA+   +  +Q  G +RAD + RQ+AFE+H
Sbjct  114  GCIYISGASEFDDRPGPVRDALVESVSIWQAAVLRAIVQSQTEGHLRADADDRQVAFEIH  173

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALAR  103
               +  ++    L   G+  RA    +  LAR
Sbjct  174  GLILALHYEARFLQVPGSIGRATVGFNNILAR  205


>gi|319761393|ref|YP_004125330.1| regulatory protein tetr [Alicycliphilus denitrificans BC]
 gi|317115954|gb|ADU98442.1| regulatory protein TetR [Alicycliphilus denitrificans BC]
Length=218

 Score = 56.6 bits (135),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 30/92 (33%), Positives = 46/92 (50%), Gaps = 0/92 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +A +     AA+   +   +  GEIR  +   Q+ FE+H
Sbjct  121  GCIYISGAVEFDDRAGPVRDALANSVLTWQAAMKRAIAQCKECGEIRPGVSEEQMLFEIH  180

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALAR  103
               +  ++    L   G+ ERA T  D  LAR
Sbjct  181  GLILALHYEARFLHTPGSMERANTGFDNILAR  212


>gi|119715467|ref|YP_922432.1| TetR family transcriptional regulator [Nocardioides sp. JS614]
 gi|119536128|gb|ABL80745.1| transcriptional regulator, TetR family [Nocardioides sp. JS614]
Length=196

 Score = 56.6 bits (135),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 31/89 (35%), Positives = 48/89 (54%), Gaps = 0/89 (0%)

Query  10   AGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFE  69
            AGGC F  A ++ D Q GPVR+ +  + R    ++   V TA   G+  AD+++ Q AFE
Sbjct  99   AGGCLFVDAVSEFDDQDGPVREELLRSERDKAESVMTIVATAVAEGDFAADLDLEQFAFE  158

Query  70   LHAYAMEANWALLLLDDDGAGERARTAID  98
            L    +  + +  +L    A +RARTA +
Sbjct  159  LEGIMLTHHHSCRMLRVPDATDRARTAFE  187


>gi|330823263|ref|YP_004386566.1| regulatory protein TetR [Alicycliphilus denitrificans K601]
 gi|329308635|gb|AEB83050.1| regulatory protein TetR [Alicycliphilus denitrificans K601]
Length=218

 Score = 56.6 bits (135),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 30/92 (33%), Positives = 46/92 (50%), Gaps = 0/92 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +A +     AA+   +   +  GEIR  +   Q+ FE+H
Sbjct  121  GCIYISGAVEFDDRAGPVRDALANSVLTWQAAMKRAIAQCKECGEIRPGVSEEQMLFEIH  180

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALAR  103
               +  ++    L   G+ ERA T  D  LAR
Sbjct  181  GLILALHYEARFLHTPGSMERANTGFDNILAR  212


>gi|197123598|ref|YP_002135549.1| TetR family transcriptional regulator [Anaeromyxobacter sp. K]
 gi|196173447|gb|ACG74420.1| transcriptional regulator, TetR family [Anaeromyxobacter sp. 
K]
Length=198

 Score = 56.2 bits (134),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 28/78 (36%), Positives = 44/78 (57%), Gaps = 0/78 (0%)

Query  9    RAGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAF  68
            + GGC F  AA ++D +PGP R+ + +  RA +  +      A+  G+ RAD++  Q+AF
Sbjct  99   QPGGCVFVQAAVELDDRPGPARELLVSMERAWLGTLARVARDARDGGQFRADVDPDQVAF  158

Query  69   ELHAYAMEANWALLLLDD  86
            ELH   +  + A  LL D
Sbjct  159  ELHGIMLSTHHAWRLLGD  176


>gi|302870404|ref|YP_003839041.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029]
 gi|315503319|ref|YP_004082206.1| regulatory protein TetR [Micromonospora sp. L5]
 gi|302573263|gb|ADL49465.1| regulatory protein TetR [Micromonospora aurantiaca ATCC 27029]
 gi|315409938|gb|ADU08055.1| regulatory protein TetR [Micromonospora sp. L5]
Length=212

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 33/87 (38%), Positives = 47/87 (55%), Gaps = 0/87 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCFFA    + +++PGPVRDR+A       A +   V+ A   GE+ AD++V  LA+E+
Sbjct  107  GGCFFANTEFEYNARPGPVRDRLAEAFARWTALLERLVQEAVDLGELPADLDVPLLAYEI  166

Query  71   HAYAMEANWALLLLDDDGAGERARTAI  97
             A  + A     LLD D     AR  +
Sbjct  167  DALGISAVMRSRLLDPDATYRHARQGL  193


>gi|220918390|ref|YP_002493694.1| TetR family transcriptional regulator [Anaeromyxobacter dehalogenans 
2CP-1]
 gi|219956244|gb|ACL66628.1| transcriptional regulator, TetR family [Anaeromyxobacter dehalogenans 
2CP-1]
Length=198

 Score = 55.8 bits (133),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 28/78 (36%), Positives = 44/78 (57%), Gaps = 0/78 (0%)

Query  9    RAGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAF  68
            + GGC F  AA ++D +PGP R+ + +  RA +  +      A+  G+ RAD++  Q+AF
Sbjct  99   QPGGCVFVQAAVELDDRPGPARELLVSMERAWLGTLARVARDARDGGQFRADVDPDQVAF  158

Query  69   ELHAYAMEANWALLLLDD  86
            ELH   +  + A  LL D
Sbjct  159  ELHGIMLTTHHAWRLLGD  176


>gi|121608206|ref|YP_996013.1| TetR family transcriptional regulator [Verminephrobacter eiseniae 
EF01-2]
 gi|121552846|gb|ABM56995.1| transcriptional regulator, TetR family [Verminephrobacter eiseniae 
EF01-2]
Length=269

 Score = 55.5 bits (132),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 28/94 (30%), Positives = 45/94 (48%), Gaps = 0/94 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +  +      A+   +E  +  G++R D    Q+ FE+H
Sbjct  152  GCIYISGAVEFDDRSGPVRDALVHSVLTWHTAMLRAIEQCKEAGQLRPDTREEQMLFEIH  211

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALARVG  105
               +  ++    L   GA ERA+      LAR G
Sbjct  212  GLILALHYEARFLQAPGAPERAQAGFHHILARYG  245


>gi|326318790|ref|YP_004236462.1| regulatory protein TetR [Acidovorax avenae subsp. avenae ATCC 
19860]
 gi|323375626|gb|ADX47895.1| regulatory protein TetR [Acidovorax avenae subsp. avenae ATCC 
19860]
Length=256

 Score = 55.5 bits (132),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 29/92 (32%), Positives = 47/92 (52%), Gaps = 0/92 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +A +     AA+   ++  +  GE+ AD+E  Q+ FE+H
Sbjct  158  GCIYISGAVEFDDRTGPVRDALANSVLTWHAAMKRAIDQCKELGEVGADVESEQMLFEIH  217

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALAR  103
               +  ++    L   G+  RA    D  LAR
Sbjct  218  GLILALHYEARFLQTPGSLGRATAGFDNILAR  249


>gi|120612727|ref|YP_972405.1| TetR family transcriptional regulator [Acidovorax citrulli AAC00-1]
 gi|120591191|gb|ABM34631.1| transcriptional regulator, TetR family [Acidovorax citrulli AAC00-1]
Length=342

 Score = 55.1 bits (131),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 29/92 (32%), Positives = 47/92 (52%), Gaps = 0/92 (0%)

Query  12   GCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFELH  71
            GC + + A + D + GPVRD +A +     AA+   ++  +  GE+ AD+E  Q+ FE+H
Sbjct  244  GCIYISGAVEFDDRTGPVRDALANSVLTWHAAMKRAIDQCKELGEVGADVESEQMLFEIH  303

Query  72   AYAMEANWALLLLDDDGAGERARTAIDAALAR  103
               +  ++    L   G+  RA    D  LAR
Sbjct  304  GLILALHYEARFLQTPGSLGRATAGFDNILAR  335


>gi|284030443|ref|YP_003380374.1| TetR family transcriptional regulator [Kribbella flavida DSM 
17836]
 gi|283809736|gb|ADB31575.1| transcriptional regulator, TetR family [Kribbella flavida DSM 
17836]
Length=211

 Score = 55.1 bits (131),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 40/92 (44%), Positives = 51/92 (56%), Gaps = 3/92 (3%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCFFA  + +  ++PG VRD +A      +A +   V  A   GE+ AD     LAFEL
Sbjct  110  GGCFFAKTSHEFGARPGGVRDYLAEVNGEWMALVEQVVAEAVELGELDADPA--HLAFEL  167

Query  71   HAYAMEANWALLLLDD-DGAGERARTAIDAAL  101
            +A+   AN A LL DD D    +ARTAI A L
Sbjct  168  NAFYDSANLASLLRDDHDTIYGQARTAIRARL  199


>gi|284029822|ref|YP_003379753.1| TetR family transcriptional regulator [Kribbella flavida DSM 
17836]
 gi|283809115|gb|ADB30954.1| transcriptional regulator, TetR family [Kribbella flavida DSM 
17836]
Length=198

 Score = 53.5 bits (127),  Expect = 9e-06, Method: Compositional matrix adjust.
 Identities = 29/75 (39%), Positives = 40/75 (54%), Gaps = 1/75 (1%)

Query  11   GGCFFAAAAADVD-SQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFE  69
            GGCFF +A+A++D + PGPVRDR     R  + AI     T    G+ R D++  Q  F+
Sbjct  102  GGCFFYSASAELDDAPPGPVRDRFLQAYRDYVDAIATVFRTGITEGQFRPDVDPEQFVFD  161

Query  70   LHAYAMEANWALLLL  84
            L    M  + A  LL
Sbjct  162  LQGVLMAHHHASRLL  176


>gi|291297595|ref|YP_003508873.1| TetR family transcriptional regulator [Stackebrandtia nassauensis 
DSM 44728]
 gi|290566815|gb|ADD39780.1| transcriptional regulator, TetR family [Stackebrandtia nassauensis 
DSM 44728]
Length=216

 Score = 53.1 bits (126),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 32/96 (34%), Positives = 45/96 (47%), Gaps = 0/96 (0%)

Query  11   GGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQLAFEL  70
            GGCFF+   A+ +S+PG + D +A         +      A+  G++R D+   +L FEL
Sbjct  111  GGCFFSTVGAEFNSRPGRIHDALAKIHNRWSNLLEQQAVAAREAGQLRPDVVAERLVFEL  170

Query  71   HAYAMEANWALLLLDDDGAGERARTAIDAALARVGT  106
             A    AN    L D       AR A+   L RVGT
Sbjct  171  DALIRHANMHRQLHDSRKVLGHAREAVRDLLTRVGT  206


>gi|317125611|ref|YP_004099723.1| TetR transcriptional regulator [Intrasporangium calvum DSM 43043]
 gi|315589699|gb|ADU48996.1| transcriptional regulator, TetR family [Intrasporangium calvum 
DSM 43043]
Length=198

 Score = 53.1 bits (126),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 31/91 (35%), Positives = 45/91 (50%), Gaps = 0/91 (0%)

Query  7    TRRAGGCFFAAAAADVDSQPGPVRDRIAATGRAGIAAITADVETAQRRGEIRADIEVRQL  66
            +R  GGC F  AA++ D Q GPVRD +    R    +I   + TA   G    D++   +
Sbjct  96   SRFGGGCIFVNAASEYDDQEGPVRDELVRAERDKQESIALVIRTAVAEGHFDPDVDPALV  155

Query  67   AFELHAYAMEANWALLLLDDDGAGERARTAI  97
            A+EL    +  ++A  L+ D  A E AR A 
Sbjct  156  AYELEGILLSHHYARRLMRDPRADEHARRAF  186



Lambda     K      H
   0.319    0.133    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 127560148160


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40