BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2185c Length=144 Score E Sequences producing significant alignments: (Bits) Value gi|15609322|ref|NP_216701.1| hypothetical protein Rv2185c [Mycob... 285 1e-75 gi|118618828|ref|YP_907160.1| hypothetical protein MUL_3540 [Myc... 262 1e-68 gi|240168243|ref|ZP_04746902.1| hypothetical protein MkanA1_0295... 236 9e-61 gi|336461907|gb|EGO40760.1| Polyketide cyclase / dehydrase and l... 231 3e-59 gi|15827411|ref|NP_301674.1| hypothetical protein ML0889 [Mycoba... 230 5e-59 gi|41408021|ref|NP_960857.1| hypothetical protein MAP1923c [Myco... 230 6e-59 gi|118465021|ref|YP_881513.1| cyclase/dehydrase [Mycobacterium a... 228 2e-58 gi|120404519|ref|YP_954348.1| cyclase/dehydrase [Mycobacterium v... 219 1e-55 gi|254819754|ref|ZP_05224755.1| hypothetical protein MintA_07514... 219 1e-55 gi|296166049|ref|ZP_06848498.1| cyclase/dehydrase [Mycobacterium... 218 2e-55 gi|145223551|ref|YP_001134229.1| cyclase/dehydrase [Mycobacteriu... 217 4e-55 gi|333990358|ref|YP_004522972.1| hypothetical protein JDM601_171... 216 1e-54 gi|342859895|ref|ZP_08716548.1| hypothetical protein MCOL_13488 ... 212 1e-53 gi|169629068|ref|YP_001702717.1| hypothetical protein MAB_1981 [... 204 4e-51 gi|108800246|ref|YP_640443.1| cyclase/dehydrase [Mycobacterium s... 197 4e-49 gi|126435869|ref|YP_001071560.1| cyclase/dehydrase [Mycobacteriu... 194 3e-48 gi|118473900|ref|YP_888528.1| cyclase/dehydrase [Mycobacterium s... 194 3e-48 gi|311895583|dbj|BAJ27991.1| hypothetical protein KSE_21690 [Kit... 161 3e-38 gi|317506590|ref|ZP_07964382.1| polyketide cyclase/dehydrase and... 161 3e-38 gi|296393487|ref|YP_003658371.1| cyclase/dehydrase [Segniliparus... 156 1e-36 gi|134098279|ref|YP_001103940.1| cyclase/dehydrase [Saccharopoly... 149 1e-34 gi|336119808|ref|YP_004574585.1| hypothetical protein MLP_41680 ... 149 1e-34 gi|54023684|ref|YP_117926.1| hypothetical protein nfa17160 [Noca... 149 1e-34 gi|258653397|ref|YP_003202553.1| cyclase/dehydrase [Nakamurella ... 146 9e-34 gi|317125100|ref|YP_004099212.1| cyclase/dehydrase [Intrasporang... 145 2e-33 gi|328881837|emb|CCA55076.1| hypothetical protein SVEN_1789 [Str... 145 2e-33 gi|240168197|ref|ZP_04746856.1| hypothetical protein MkanA1_0271... 145 2e-33 gi|331696583|ref|YP_004332822.1| cyclase/dehydrase [Pseudonocard... 144 3e-33 gi|324999922|ref|ZP_08121034.1| hypothetical protein PseP1_14190... 144 3e-33 gi|312140175|ref|YP_004007511.1| hypothetical protein REQ_28120 ... 144 3e-33 gi|182439167|ref|YP_001826886.1| hypothetical protein SGR_5374 [... 144 4e-33 gi|297161241|gb|ADI10953.1| hypothetical protein SBI_07833 [Stre... 144 4e-33 gi|21220606|ref|NP_626385.1| hypothetical protein SCO2129 [Strep... 144 5e-33 gi|297194841|ref|ZP_06912239.1| cyclase [Streptomyces pristinaes... 144 6e-33 gi|302534007|ref|ZP_07286349.1| cyclase [Streptomyces sp. C] >gi... 143 7e-33 gi|329940989|ref|ZP_08290269.1| hypothetical protein SGM_5761 [S... 143 9e-33 gi|111018132|ref|YP_701104.1| hypothetical protein RHA1_ro01119 ... 142 1e-32 gi|29832613|ref|NP_827247.1| hypothetical protein SAV_6071 [Stre... 142 2e-32 gi|226360261|ref|YP_002778039.1| hypothetical protein ROP_08470 ... 142 2e-32 gi|291440137|ref|ZP_06579527.1| cyclase/dehydrase [Streptomyces ... 141 2e-32 gi|254382641|ref|ZP_04997999.1| conserved hypothetical protein [... 141 3e-32 gi|345014505|ref|YP_004816859.1| cyclase/dehydrase [Streptomyces... 141 3e-32 gi|320011240|gb|ADW06090.1| Polyketide cyclase/dehydrase [Strept... 141 3e-32 gi|239987099|ref|ZP_04707763.1| hypothetical protein SrosN1_0731... 140 5e-32 gi|302550842|ref|ZP_07303184.1| cyclase/dehydrase [Streptomyces ... 140 6e-32 gi|271964210|ref|YP_003338406.1| hypothetical protein Sros_2698 ... 139 1e-31 gi|337765268|emb|CCB73977.1| conserved protein of unknown functi... 139 1e-31 gi|254393052|ref|ZP_05008214.1| cyclase/dehydrase [Streptomyces ... 139 1e-31 gi|344999162|ref|YP_004802016.1| cyclase/dehydrase [Streptomyces... 139 2e-31 gi|326333547|ref|ZP_08199787.1| cyclase/dehydrase [Nocardioidace... 139 2e-31 >gi|15609322|ref|NP_216701.1| hypothetical protein Rv2185c [Mycobacterium tuberculosis H37Rv] gi|15841675|ref|NP_336712.1| hypothetical protein MT2240 [Mycobacterium tuberculosis CDC1551] gi|31793363|ref|NP_855856.1| hypothetical protein Mb2207c [Mycobacterium bovis AF2122/97] 80 more sequence titles Length=144 Score = 285 bits (730), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 143/144 (99%), Positives = 144/144 (100%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +ADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI Sbjct 1 MADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG Sbjct 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 MLKRKAERRLIDGALKDLKKRVEG Sbjct 121 MLKRKAERRLIDGALKDLKKRVEG 144 >gi|118618828|ref|YP_907160.1| hypothetical protein MUL_3540 [Mycobacterium ulcerans Agy99] gi|183983219|ref|YP_001851510.1| hypothetical protein MMAR_3229 [Mycobacterium marinum M] gi|118570938|gb|ABL05689.1| conserved protein [Mycobacterium ulcerans Agy99] gi|183176545|gb|ACC41655.1| conserved protein [Mycobacterium marinum M] Length=144 Score = 262 bits (670), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 128/144 (89%), Positives = 139/144 (97%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +ADKTTQTIYIDA+PGEVMKAIADIEAYP+WISEYKEVEILEADD+GYP ARMLMDA I Sbjct 1 MADKTTQTIYIDAEPGEVMKAIADIEAYPEWISEYKEVEILEADDDGYPMLARMLMDATI 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 FKDTLIM+YEWP DRQSLSWTL+SSSLLK+LEG+Y LAPKGSGT+VTYEL+VDLA+PMIG Sbjct 61 FKDTLIMAYEWPADRQSLSWTLQSSSLLKALEGSYHLAPKGSGTDVTYELSVDLAIPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 MLKRKAERRLIDGALKDLKKRVEG Sbjct 121 MLKRKAERRLIDGALKDLKKRVEG 144 >gi|240168243|ref|ZP_04746902.1| hypothetical protein MkanA1_02952 [Mycobacterium kansasii ATCC 12478] Length=145 Score = 236 bits (602), Expect = 9e-61, Method: Compositional matrix adjust. Identities = 127/144 (89%), Positives = 136/144 (95%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +ADKT QTIYIDA PGEVMKAIADIEAYP+WISEYKEVE+LEADDEGYP+RARMLMDA I Sbjct 1 MADKTRQTIYIDAAPGEVMKAIADIEAYPEWISEYKEVEVLEADDEGYPQRARMLMDATI 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 F+DTLIM+Y+WP DRQSLSWTLESSSLLKSLEG+Y L P GSGT+VTYELAVDLAVPMIG Sbjct 61 FRDTLIMAYQWPADRQSLSWTLESSSLLKSLEGSYILEPNGSGTDVTYELAVDLAVPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 MLKRKAERRLIDGALKDLKKRVE Sbjct 121 MLKRKAERRLIDGALKDLKKRVEA 144 >gi|336461907|gb|EGO40760.1| Polyketide cyclase / dehydrase and lipid transport [Mycobacterium avium subsp. paratuberculosis S397] Length=174 Score = 231 bits (589), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 109/144 (76%), Positives = 131/144 (91%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 VA+KTTQTIYI+ADP VMK IADI++YPQWISEYKE E++E D +GYPK AR++MDA + Sbjct 30 VAEKTTQTIYIEADPDTVMKVIADIDSYPQWISEYKEAEVVEKDADGYPKVARIVMDATV 89 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT++MSY+WP+DR+S+SWTL SSSLL++LEG+YRLAPKGSGTEVTYEL+VDLA+PMIG Sbjct 90 LKDTMVMSYQWPKDRRSVSWTLVSSSLLRALEGSYRLAPKGSGTEVTYELSVDLAMPMIG 149 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 +LKRKAERRL D ALKDLKKRVE Sbjct 150 LLKRKAERRLTDTALKDLKKRVEA 173 >gi|15827411|ref|NP_301674.1| hypothetical protein ML0889 [Mycobacterium leprae TN] gi|221229888|ref|YP_002503304.1| hypothetical protein MLBr_00889 [Mycobacterium leprae Br4923] gi|3080496|emb|CAA18693.1| hypothetical protein MLCB268.27c [Mycobacterium leprae] gi|13092961|emb|CAC31270.1| conserved hypothetical protein [Mycobacterium leprae] gi|219932995|emb|CAR70984.1| conserved hypothetical protein [Mycobacterium leprae Br4923] Length=144 Score = 230 bits (587), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 122/144 (85%), Positives = 131/144 (91%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +ADKTTQT YIDA+PGEVMK IADIE+YPQWISEYKEVE+LE DDE +PKRARMLMDA I Sbjct 1 MADKTTQTFYIDANPGEVMKTIADIESYPQWISEYKEVEVLEVDDEDFPKRARMLMDAKI 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 FKDTLIMSY+W D QS+SW LESSSLLKSLEG+YRL PKGS TEVTYELAVD A+PMIG Sbjct 61 FKDTLIMSYDWTADHQSVSWILESSSLLKSLEGSYRLVPKGSTTEVTYELAVDFAIPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 MLKRKAE RLIDGALKDLKKRVEG Sbjct 121 MLKRKAEHRLIDGALKDLKKRVEG 144 >gi|41408021|ref|NP_960857.1| hypothetical protein MAP1923c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396376|gb|AAS04240.1| hypothetical protein MAP_1923c [Mycobacterium avium subsp. paratuberculosis K-10] Length=145 Score = 230 bits (586), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 108/144 (75%), Positives = 131/144 (91%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+KTTQTIYI+ADP VMK IADI++YPQWISEYKE E++E D +GYPK AR++MDA + Sbjct 1 MAEKTTQTIYIEADPDTVMKVIADIDSYPQWISEYKEAEVVEKDADGYPKVARIVMDATV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT++MSY+WP+DR+S+SWTL SSSLL++LEG+YRLAPKGSGTEVTYEL+VDLA+PMIG Sbjct 61 LKDTMVMSYQWPKDRRSVSWTLVSSSLLRALEGSYRLAPKGSGTEVTYELSVDLAMPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 +LKRKAERRL D ALKDLKKRVE Sbjct 121 LLKRKAERRLTDTALKDLKKRVEA 144 >gi|118465021|ref|YP_881513.1| cyclase/dehydrase [Mycobacterium avium 104] gi|254774981|ref|ZP_05216497.1| cyclase/dehydrase [Mycobacterium avium subsp. avium ATCC 25291] gi|118166308|gb|ABK67205.1| cyclase/dehydrase [Mycobacterium avium 104] Length=145 Score = 228 bits (582), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 107/144 (75%), Positives = 131/144 (91%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+KTTQTIYI+ADP VMK IADI++YP+WISEYKE E++E D +GYPK AR++MDA + Sbjct 1 MAEKTTQTIYIEADPDTVMKVIADIDSYPRWISEYKEAEVVEKDADGYPKVARIVMDATV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT++MSY+WP+DR+S+SWTL SSSLL++LEG+YRLAPKGSGTEVTYEL+VDLA+PMIG Sbjct 61 LKDTMVMSYQWPKDRRSVSWTLVSSSLLRALEGSYRLAPKGSGTEVTYELSVDLAMPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 +LKRKAERRL D ALKDLKKRVE Sbjct 121 LLKRKAERRLTDTALKDLKKRVEA 144 >gi|120404519|ref|YP_954348.1| cyclase/dehydrase [Mycobacterium vanbaalenii PYR-1] gi|119957337|gb|ABM14342.1| cyclase/dehydrase [Mycobacterium vanbaalenii PYR-1] Length=145 Score = 219 bits (558), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 101/144 (71%), Positives = 125/144 (87%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +ADKT QTIYIDADP VM IADI +YP+W++EYKE E+LEAD EGYPK AR+++DAA+ Sbjct 1 MADKTAQTIYIDADPSTVMDVIADIGSYPEWVAEYKEAEVLEADAEGYPKVARLVLDAAV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KD+++++Y WP DR S++W+L SS+LLKSL+G YRLAPKGSGT+VTYEL+VDL +PMIG Sbjct 61 LKDSMVLAYRWPADRNSVTWSLVSSTLLKSLDGAYRLAPKGSGTDVTYELSVDLIIPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 +LKRKAERRL D ALKDLKKRVE Sbjct 121 LLKRKAERRLTDTALKDLKKRVEA 144 >gi|254819754|ref|ZP_05224755.1| hypothetical protein MintA_07514 [Mycobacterium intracellulare ATCC 13950] Length=145 Score = 219 bits (558), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 111/144 (78%), Positives = 131/144 (91%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+KTTQTIYIDADPG VM+ IADI++YPQWISEYKE E+ E D +GYPK AR++MDA + Sbjct 1 MAEKTTQTIYIDADPGTVMRVIADIDSYPQWISEYKEAEVQEKDADGYPKVARIVMDATV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT++MSY+WP+DRQS+SWTL SSSLL+SLEG+YRLAPKGSGTEVTYEL+VDLA+PMIG Sbjct 61 LKDTMVMSYQWPKDRQSVSWTLVSSSLLRSLEGSYRLAPKGSGTEVTYELSVDLAMPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 +LKRKAERRL D ALKDLKKRVE Sbjct 121 LLKRKAERRLTDTALKDLKKRVEA 144 >gi|296166049|ref|ZP_06848498.1| cyclase/dehydrase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898614|gb|EFG78171.1| cyclase/dehydrase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=179 Score = 218 bits (555), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 113/144 (79%), Positives = 130/144 (91%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 VA+KT+QTIYI+ADPG VM IADI++YPQWISEY+E E+ E D +G PK AR+++DAA+ Sbjct 36 VAEKTSQTIYIEADPGTVMDVIADIDSYPQWISEYREAEVQETDADGNPKVARVVLDAAV 95 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDTL+MSYEWP+DRQS+SWTL SSSLL+SLEGTYRLAPKGSGTEVTYEL VDLAVPMIG Sbjct 96 LKDTLVMSYEWPKDRQSVSWTLVSSSLLRSLEGTYRLAPKGSGTEVTYELTVDLAVPMIG 155 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 +LKRKAERRL D ALKDLKKRVEG Sbjct 156 LLKRKAERRLTDTALKDLKKRVEG 179 >gi|145223551|ref|YP_001134229.1| cyclase/dehydrase [Mycobacterium gilvum PYR-GCK] gi|315443898|ref|YP_004076777.1| polyketide cyclase / dehydrase family protein [Mycobacterium sp. Spyr1] gi|145216037|gb|ABP45441.1| cyclase/dehydrase [Mycobacterium gilvum PYR-GCK] gi|315262201|gb|ADT98942.1| polyketide cyclase / dehydrase family protein [Mycobacterium sp. Spyr1] Length=145 Score = 217 bits (553), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 100/143 (70%), Positives = 124/143 (87%), Gaps = 0/143 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +ADKT QTIYIDADP VM IADI +YP W++EYKE E+LEAD EGYPK AR+++DAA+ Sbjct 1 MADKTAQTIYIDADPSTVMDVIADIGSYPDWVAEYKETEVLEADAEGYPKVARLVLDAAV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT++++Y WP D +S++W+L SSSLLK+L+G YRL+PKGSGT+VTYEL+VDL +PMIG Sbjct 61 LKDTMVLAYRWPADHKSVTWSLVSSSLLKALDGAYRLSPKGSGTDVTYELSVDLVIPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVE 143 +LKRKAERRL D ALKDLKKRVE Sbjct 121 LLKRKAERRLTDTALKDLKKRVE 143 >gi|333990358|ref|YP_004522972.1| hypothetical protein JDM601_1718 [Mycobacterium sp. JDM601] gi|333486326|gb|AEF35718.1| conserved hypothetical protein [Mycobacterium sp. JDM601] Length=145 Score = 216 bits (549), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 99/144 (69%), Positives = 125/144 (87%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +ADKT QTI+I+ADP VMK IADI AYP+W+SEY E E+LE D +GYPK+AR+++DAA+ Sbjct 1 MADKTAQTIFIEADPDTVMKVIADIGAYPEWVSEYTEAEVLETDSDGYPKQARLVLDAAV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT++++Y+WP+DR+S+ W+L SSSLLK+L+G YRLAPKGSGTEV YEL+VDL +PMIG Sbjct 61 LKDTMVLAYDWPQDRRSVRWSLVSSSLLKALDGEYRLAPKGSGTEVVYELSVDLLIPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 +LKRKAERRL D ALKDLKKR E Sbjct 121 LLKRKAERRLTDTALKDLKKRAEA 144 >gi|342859895|ref|ZP_08716548.1| hypothetical protein MCOL_13488 [Mycobacterium colombiense CECT 3035] gi|342133027|gb|EGT86247.1| hypothetical protein MCOL_13488 [Mycobacterium colombiense CECT 3035] Length=145 Score = 212 bits (540), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 109/144 (76%), Positives = 129/144 (90%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+KTTQTIYI+ADP VM+ IADI++YPQWISEYKE E+ E D +GYPK AR++MDA + Sbjct 1 MAEKTTQTIYIEADPATVMQVIADIDSYPQWISEYKEAEVQEKDADGYPKVARIVMDATV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT++MSYEWP+DRQS+SWTL SSSLL+SLEG+YRLA KGSGTEVTYEL+VDLA+PMIG Sbjct 61 IKDTMVMSYEWPKDRQSVSWTLVSSSLLRSLEGSYRLAGKGSGTEVTYELSVDLAMPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 +LKRKAERRL D ALKDLKKRVE Sbjct 121 LLKRKAERRLTDTALKDLKKRVEA 144 >gi|169629068|ref|YP_001702717.1| hypothetical protein MAB_1981 [Mycobacterium abscessus ATCC 19977] gi|169241035|emb|CAM62063.1| Conserved hypothetical protein [Mycobacterium abscessus] Length=146 Score = 204 bits (519), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 98/143 (69%), Positives = 119/143 (84%), Gaps = 0/143 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+KTTQTI IDA+PG+VM IADI AYP+W+SEYKE E+L+ D EG KRAR+++DA + Sbjct 1 MAEKTTQTIAIDAEPGKVMAVIADIGAYPEWVSEYKETEVLDTDSEGRVKRARLVLDAGV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT ++ Y W D + ++WTL SSLL+SLEGTY LAPKGSGTEVTYELAVDL +PMIG Sbjct 61 LKDTQVLEYVWSPDGRKVTWTLAESSLLRSLEGTYLLAPKGSGTEVTYELAVDLQIPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVE 143 MLKRKAER++ D ALKDLKKRVE Sbjct 121 MLKRKAERKITDSALKDLKKRVE 143 >gi|108800246|ref|YP_640443.1| cyclase/dehydrase [Mycobacterium sp. MCS] gi|119869374|ref|YP_939326.1| cyclase/dehydrase [Mycobacterium sp. KMS] gi|108770665|gb|ABG09387.1| cyclase/dehydrase [Mycobacterium sp. MCS] gi|119695463|gb|ABL92536.1| cyclase/dehydrase [Mycobacterium sp. KMS] Length=145 Score = 197 bits (501), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 99/144 (69%), Positives = 123/144 (86%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +ADKT QTIYI+ADP VM IADI +YP+W+ EY+E E+L+ D +GYPK AR+++DAA+ Sbjct 1 MADKTAQTIYIEADPATVMDVIADIGSYPEWVKEYRETEVLDTDADGYPKTARLVLDAAV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT++++Y+WP DR S++WTL SSSLLKSLEG YRLAPKGSGT+VTYELAVDL +PMIG Sbjct 61 LKDTMVLAYQWPADRTSVTWTLVSSSLLKSLEGAYRLAPKGSGTDVTYELAVDLMIPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 +LKRKAERRL + ALKDLKKR E Sbjct 121 LLKRKAERRLTETALKDLKKRAEA 144 >gi|126435869|ref|YP_001071560.1| cyclase/dehydrase [Mycobacterium sp. JLS] gi|126235669|gb|ABN99069.1| cyclase/dehydrase [Mycobacterium sp. JLS] Length=145 Score = 194 bits (494), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 98/144 (69%), Positives = 122/144 (85%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +ADKT QTIYI+ADP VM IADI +YP+W+ EY+E E+L+ D +GYPK AR+++DAA+ Sbjct 1 MADKTAQTIYIEADPATVMDVIADIGSYPEWVKEYRETEVLDTDADGYPKTARLVLDAAV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT++++Y+W DR S++WTL SSSLLKSLEG YRLAPKGSGT+VTYELAVDL +PMIG Sbjct 61 LKDTMVLAYQWAADRTSVTWTLVSSSLLKSLEGAYRLAPKGSGTDVTYELAVDLMIPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 +LKRKAERRL + ALKDLKKR E Sbjct 121 LLKRKAERRLTETALKDLKKRAEA 144 >gi|118473900|ref|YP_888528.1| cyclase/dehydrase [Mycobacterium smegmatis str. MC2 155] gi|118175187|gb|ABK76083.1| cyclase/dehydrase [Mycobacterium smegmatis str. MC2 155] Length=145 Score = 194 bits (494), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 98/143 (69%), Positives = 121/143 (85%), Gaps = 0/143 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +ADKT QTIYI+ADP V+ IADI +YP+W++EYKE E+LE DD G PK+AR+++DAA+ Sbjct 1 MADKTAQTIYIEADPKTVIDVIADIGSYPEWVAEYKETEVLEVDDNGNPKKARLVLDAAV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT+++ Y WP DR S++W+L SSSLL+SL G YRL+PKGSGTEVTYEL+VDL VPMIG Sbjct 61 LKDTMVLEYVWPPDRTSVTWSLVSSSLLRSLNGAYRLSPKGSGTEVTYELSVDLVVPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVE 143 +LKRKAERRL D ALKDLKKR E Sbjct 121 LLKRKAERRLTDTALKDLKKRAE 143 >gi|311895583|dbj|BAJ27991.1| hypothetical protein KSE_21690 [Kitasatospora setae KM-6054] Length=143 Score = 161 bits (407), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 78/144 (55%), Positives = 104/144 (73%), Gaps = 1/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T +I IDA P EVM IAD AYPQW E KEV++LE +G R R+L+DA Sbjct 1 MAEHTRSSIVIDATPAEVMAVIADFAAYPQWTGEVKEVDVLETGPDGRATRVRLLLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 +D ++Y W DR+ + WTL SS +L++L+G+Y LAP G+GTEVTY+LAVD+ +PM+G Sbjct 61 IRDEHTLAYTWDGDRE-VGWTLVSSQMLRALDGSYALAPAGAGTEVTYQLAVDVKIPMLG 119 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 M+KRKAE+ +ID AL LKKRVEG Sbjct 120 MIKRKAEKVIIDRALAGLKKRVEG 143 >gi|317506590|ref|ZP_07964382.1| polyketide cyclase/dehydrase and lipid transporter [Segniliparus rugosus ATCC BAA-974] gi|316255099|gb|EFV14377.1| polyketide cyclase/dehydrase and lipid transporter [Segniliparus rugosus ATCC BAA-974] Length=146 Score = 161 bits (407), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 77/144 (54%), Positives = 102/144 (71%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +AD T Q+I I A P +VM IAD++ YP+W+ K VEILE D G+ +AR ++DAA+ Sbjct 1 MADHTNQSIVIGAKPADVMAVIADLDRYPEWVDAAKSVEILERDKNGFAAKARFVLDAAL 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT + Y W ED S+ WTL S++++S EG Y L P GT+VTYEL+VDL +PMIG Sbjct 61 LKDTYELRYTWAEDGLSVRWTLLESTIMRSQEGAYLLEPNEKGTKVTYELSVDLRIPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 + +RKAER +ID ALK+LKKRVE Sbjct 121 LFRRKAERAIIDTALKELKKRVES 144 >gi|296393487|ref|YP_003658371.1| cyclase/dehydrase [Segniliparus rotundus DSM 44985] gi|296180634|gb|ADG97540.1| cyclase/dehydrase [Segniliparus rotundus DSM 44985] Length=146 Score = 156 bits (394), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 75/144 (53%), Positives = 101/144 (71%), Gaps = 0/144 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +AD T Q+I IDA P +VM IAD++ YP W+ + VEILE D+ G P RAR ++DA + Sbjct 1 MADHTRQSIVIDAKPEDVMAVIADLDRYPDWVDAAQSVEILERDERGTPVRARFVLDAEL 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT + Y W D +S+ WTL S++++S EG Y L P GT+ TYEL+VDL +PM+G Sbjct 61 LKDTYELRYTWARDGRSVRWTLLESTIMRSQEGAYILEPNPEGTKATYELSVDLRIPMLG 120 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 + +RKAER +ID ALK+LKKRVE Sbjct 121 LFRRKAERAIIDTALKELKKRVES 144 >gi|134098279|ref|YP_001103940.1| cyclase/dehydrase [Saccharopolyspora erythraea NRRL 2338] gi|291004301|ref|ZP_06562274.1| cyclase/dehydrase [Saccharopolyspora erythraea NRRL 2338] gi|133910902|emb|CAM01015.1| cyclase/dehydrase [Saccharopolyspora erythraea NRRL 2338] Length=147 Score = 149 bits (376), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 72/142 (51%), Positives = 99/142 (70%), Gaps = 1/142 (0%) Query 3 DKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAIFK 62 D++TQ+I I+A E+M I+D AYP+W + KE E+L G ++ R ++DA + K Sbjct 3 DQSTQSIVIEAPAAEIMAVISDFAAYPEWAAAVKETEVLSTTTGGRAEKVRFVLDAGVVK 62 Query 63 DTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKG-SGTEVTYELAVDLAVPMIGM 121 DT + Y+W ED S+SWTL + K+ G+YRL P+G S TEVTY LAVDLA+PMIGM Sbjct 63 DTYVNVYDWAEDGLSVSWTLSEGQVQKAQRGSYRLDPQGDSRTEVTYSLAVDLAIPMIGM 122 Query 122 LKRKAERRLIDGALKDLKKRVE 143 KRKAE+ ++D ALK+LK+RVE Sbjct 123 FKRKAEKMIMDTALKELKRRVE 144 >gi|336119808|ref|YP_004574585.1| hypothetical protein MLP_41680 [Microlunatus phosphovorus NM-1] gi|334687597|dbj|BAK37182.1| hypothetical protein MLP_41680 [Microlunatus phosphovorus NM-1] Length=142 Score = 149 bits (376), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 72/144 (50%), Positives = 101/144 (71%), Gaps = 2/144 (1%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +AD+T TI I A P EVM IADI AYPQW+S K+V+IL + +G P ++ ++ ++ Sbjct 1 MADQTKDTIEITASPEEVMAVIADIAAYPQWVSAMKQVDILSSHPDGRPDHVKIKLEHSV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 D ++Y+W +SW L SLLK+++G+Y LAP GT+VTY L+VD+ +PMIG Sbjct 61 VSDQYTLAYDW--QPSLVSWHLVEGSLLKAMDGSYELAPTARGTKVTYALSVDIRMPMIG 118 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 M +RKAE+ +IDGALKDLK+RVEG Sbjct 119 MFRRKAEKTIIDGALKDLKRRVEG 142 >gi|54023684|ref|YP_117926.1| hypothetical protein nfa17160 [Nocardia farcinica IFM 10152] gi|54015192|dbj|BAD56562.1| hypothetical protein [Nocardia farcinica IFM 10152] Length=145 Score = 149 bits (376), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 75/145 (52%), Positives = 103/145 (72%), Gaps = 1/145 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +AD+T ++I I+A EVM IAD+ +YP+W++ K VE+LE +G + AR ++DA + Sbjct 1 MADRTQRSILIEAPAREVMAVIADLASYPEWVAAAKSVEVLETGTDGRARTARFVLDAGV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSG-TEVTYELAVDLAVPMI 119 KDT ++SY W D +++SW L S L K+ +G+Y LA K G TEVTYEL VDL +PMI Sbjct 61 VKDTYVLSYTWRPDDRAVSWKLVSGELQKAQDGSYVLAEKPGGVTEVTYELTVDLNIPMI 120 Query 120 GMLKRKAERRLIDGALKDLKKRVEG 144 GM KRKAE+ + D ALK+LKKRVEG Sbjct 121 GMFKRKAEKVITDTALKELKKRVEG 145 >gi|258653397|ref|YP_003202553.1| cyclase/dehydrase [Nakamurella multipartita DSM 44233] gi|258556622|gb|ACV79564.1| cyclase/dehydrase [Nakamurella multipartita DSM 44233] Length=145 Score = 146 bits (369), Expect = 9e-34, Method: Compositional matrix adjust. Identities = 73/143 (52%), Positives = 98/143 (69%), Gaps = 0/143 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ ++Q+I + A+P +M IAD AYP+W K VE+ ++G K+ + MDA + Sbjct 1 MANGSSQSITMTAEPSVIMDVIADFAAYPEWAGAVKSVEVTVPGEDGRAKQVKFSMDAGL 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KDT ++Y W D S+SWTL S L KS +G+Y LA GTEVTY LAVDLAVPMIG Sbjct 61 LKDTYELAYTWAADGMSVSWTLVSGQLQKSQQGSYVLATTPKGTEVTYTLAVDLAVPMIG 120 Query 121 MLKRKAERRLIDGALKDLKKRVE 143 +L+RKAER ++D ALK+LKKRVE Sbjct 121 VLRRKAERVILDTALKELKKRVE 143 >gi|317125100|ref|YP_004099212.1| cyclase/dehydrase [Intrasporangium calvum DSM 43043] gi|315589188|gb|ADU48485.1| cyclase/dehydrase [Intrasporangium calvum DSM 43043] Length=147 Score = 145 bits (366), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 72/147 (49%), Positives = 99/147 (68%), Gaps = 3/147 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A++T +I IDA PGEV+ IAD EAYP+W E K+V IL + +G+ + +DA Sbjct 1 MAERTESSIVIDASPGEVLDVIADFEAYPEWAGEVKQVAILAEEGDGWADQVEFTLDAGA 60 Query 61 FKDTLIMSYEWPEDRQS---LSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVP 117 KDT ++ YEW D LSWTL +S+LK++ G+Y L G+ T+VTY L VD+ VP Sbjct 61 IKDTYVLDYEWDIDEDGTGVLSWTLVRASVLKAMNGSYTLEQAGAATKVTYRLTVDVKVP 120 Query 118 MIGMLKRKAERRLIDGALKDLKKRVEG 144 MIG+LKRKAE+ ++D ALK+LKKR E Sbjct 121 MIGLLKRKAEKVIVDTALKELKKRAEA 147 >gi|328881837|emb|CCA55076.1| hypothetical protein SVEN_1789 [Streptomyces venezuelae ATCC 10712] Length=145 Score = 145 bits (366), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 71/143 (50%), Positives = 98/143 (69%), Gaps = 1/143 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM IAD YP+W E KE E+LE DD G ++ R+L+DA Sbjct 1 MAEHTSSSITIEAAPADVMGVIADFARYPEWTGEVKEAEVLETDDSGRAEKVRLLLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KD ++Y W + +SWTL S +L+SL+G+YRL G TEVTY+L VD+ +PM+G Sbjct 61 IKDDHTLAYTWTGANE-VSWTLVKSQMLRSLDGSYRLTAVGDRTEVTYQLTVDVKIPMLG 119 Query 121 MLKRKAERRLIDGALKDLKKRVE 143 M+KRKAE+ +ID AL LKKRVE Sbjct 120 MIKRKAEKVIIDRALAGLKKRVE 142 >gi|240168197|ref|ZP_04746856.1| hypothetical protein MkanA1_02712 [Mycobacterium kansasii ATCC 12478] Length=146 Score = 145 bits (365), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 72/143 (51%), Positives = 100/143 (70%), Gaps = 0/143 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A ++ TI I+A P EVM IAD+E YP+W+ EYK+VE+L AD G RARM+++AAI Sbjct 1 MAGRSILTIAIEAPPDEVMAVIADMETYPEWVPEYKKVEVLRADSAGRITRARMVVEAAI 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 K ++ + W + + LSWTL S+ ++SL G Y L PK GTEV+Y+L +DL V + G Sbjct 61 IKGPHVLEFLWAPNGKELSWTLTQSNTVRSLVGRYTLIPKDYGTEVSYQLTIDLRVSVPG 120 Query 121 MLKRKAERRLIDGALKDLKKRVE 143 ++KR+AER +ID ALK LK RVE Sbjct 121 IIKRRAERAVIDTALKALKARVE 143 >gi|331696583|ref|YP_004332822.1| cyclase/dehydrase [Pseudonocardia dioxanivorans CB1190] gi|326951272|gb|AEA24969.1| cyclase/dehydrase [Pseudonocardia dioxanivorans CB1190] Length=144 Score = 144 bits (364), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 75/143 (53%), Positives = 92/143 (65%), Gaps = 1/143 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +AD TT +I I ADP VM IAD EAYP+W + K VEIL+ D G +R R MDA Sbjct 1 MADATTSSISIAADPQRVMAVIADFEAYPKWAEQVKTVEILDEAD-GRARRVRFTMDAGP 59 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KD+ + Y+W D S+SW L + KS G+Y L G T VTY LAVDL +PMIG Sbjct 60 IKDSYTLDYDWAPDGNSVSWNLVKGQMQKSQNGSYVLVADGDSTTVTYSLAVDLNIPMIG 119 Query 121 MLKRKAERRLIDGALKDLKKRVE 143 ML+RKAE+ +ID ALK LK+RVE Sbjct 120 MLRRKAEKVIIDTALKGLKRRVE 142 >gi|324999922|ref|ZP_08121034.1| hypothetical protein PseP1_14190 [Pseudonocardia sp. P1] Length=145 Score = 144 bits (364), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 74/146 (51%), Positives = 99/146 (68%), Gaps = 6/146 (4%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARML---MD 57 +AD TT +I+IDA P +VM IAD E+YP+W + VEIL D G +RAR + MD Sbjct 1 MADATTSSIHIDAPPDQVMAVIADFESYPEWTDQITAVEIL---DPGAGERARQVQFSMD 57 Query 58 AAIFKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVP 117 A KD+ + Y+W +D +S+SWTL + K+ +G YRL P GT VTYEL+V++ P Sbjct 58 AGAIKDSYTLDYDWADDDRSVSWTLVKGGIQKAQDGAYRLDPDAGGTTVTYELSVEVNFP 117 Query 118 MIGMLKRKAERRLIDGALKDLKKRVE 143 MIGML+RKAE+ +ID ALK LK+RVE Sbjct 118 MIGMLRRKAEKVIIDAALKGLKRRVE 143 >gi|312140175|ref|YP_004007511.1| hypothetical protein REQ_28120 [Rhodococcus equi 103S] gi|325676943|ref|ZP_08156615.1| cyclase/dehydrase [Rhodococcus equi ATCC 33707] gi|311889514|emb|CBH48831.1| conserved hypothetical protein [Rhodococcus equi 103S] gi|325552243|gb|EGD21933.1| cyclase/dehydrase [Rhodococcus equi ATCC 33707] Length=145 Score = 144 bits (364), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 73/145 (51%), Positives = 95/145 (66%), Gaps = 1/145 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+KT ++I IDA EVM IAD AYP W+ K VE+L + +G R ++DA + Sbjct 1 MAEKTKRSITIDAPAAEVMGVIADFGAYPSWVEAAKSVEVLASGPDGRADEVRFVLDAGM 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPK-GSGTEVTYELAVDLAVPMI 119 KDT ++ Y W D ++SW L S + KS G+Y L P+ G GT VTYEL VDL +PMI Sbjct 61 VKDTYVLRYRWAPDGMAVSWDLVSGEIQKSQHGSYTLEPEAGGGTRVTYELTVDLTIPMI 120 Query 120 GMLKRKAERRLIDGALKDLKKRVEG 144 G+ KRKAER + D ALK+LKKRVEG Sbjct 121 GLFKRKAERVITDTALKELKKRVEG 145 >gi|182439167|ref|YP_001826886.1| hypothetical protein SGR_5374 [Streptomyces griseus subsp. griseus NBRC 13350] gi|326779819|ref|ZP_08239084.1| cyclase/dehydrase [Streptomyces cf. griseus XylebKG-1] gi|178467683|dbj|BAG22203.1| conserved hypothetical protein [Streptomyces griseus subsp. griseus NBRC 13350] gi|326660152|gb|EGE44998.1| cyclase/dehydrase [Streptomyces griseus XylebKG-1] Length=149 Score = 144 bits (364), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 71/145 (49%), Positives = 101/145 (70%), Gaps = 3/145 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM IAD YP+W E KE E+L DD G ++ R+++DA Sbjct 1 MAEHTSSSITIEAAPADVMSVIADFARYPEWTGEVKEAEVLSTDDRGRAEQVRLVLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSG--TEVTYELAVDLAVPM 118 KD +++Y W + + +SW+L S +L+SL+GTY LAP G G TEVTY LAVD+ +P+ Sbjct 61 IKDDHVLAYTWNGENE-VSWSLVKSQMLRSLDGTYALAPLGGGERTEVTYRLAVDVKIPL 119 Query 119 IGMLKRKAERRLIDGALKDLKKRVE 143 +GM+KRKAE+ +ID AL LKKRVE Sbjct 120 LGMIKRKAEKVIIDRALAGLKKRVE 144 >gi|297161241|gb|ADI10953.1| hypothetical protein SBI_07833 [Streptomyces bingchenggensis BCW-1] Length=147 Score = 144 bits (363), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 73/145 (51%), Positives = 101/145 (70%), Gaps = 3/145 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM+ IAD + YP+W E KE ++L DD G ++ RML+DA Sbjct 1 MAEHTSSSITIEAAPADVMEVIADFDRYPEWSGEVKEADVLTKDDRGRAEKVRMLLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSG--TEVTYELAVDLAVPM 118 KD + Y W D Q +SW+L S +L+SL+G+Y LAP SG TEVTY+L VD+ +PM Sbjct 61 IKDDYTLEYTWTGDNQ-VSWSLVKSQMLRSLDGSYLLAPVDSGKRTEVTYQLTVDVKIPM 119 Query 119 IGMLKRKAERRLIDGALKDLKKRVE 143 +GM+KRKAE+ +ID AL LKKRVE Sbjct 120 LGMIKRKAEKVIIDRALAGLKKRVE 144 >gi|21220606|ref|NP_626385.1| hypothetical protein SCO2129 [Streptomyces coelicolor A3(2)] gi|289772146|ref|ZP_06531524.1| cyclase/dehydrase [Streptomyces lividans TK24] gi|4539198|emb|CAB39856.1| conserved hypothetical protein [Streptomyces coelicolor A3(2)] gi|289702345|gb|EFD69774.1| cyclase/dehydrase [Streptomyces lividans TK24] Length=144 Score = 144 bits (362), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 69/143 (49%), Positives = 98/143 (69%), Gaps = 1/143 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM IAD YP W E KE ++L D++G ++ R++MDA Sbjct 1 MAEHTSSSITIEAAPADVMAVIADFARYPDWTGEVKEAQVLATDEQGRAEQVRLVMDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KD + Y W + + +SWTL S +L+SL+G+Y L P G+GTEVTY L VD+ +PM+G Sbjct 61 IKDDQTLGYTWTGEHE-VSWTLVKSQMLRSLDGSYLLRPAGTGTEVTYRLTVDVKIPMLG 119 Query 121 MLKRKAERRLIDGALKDLKKRVE 143 M+KRKAE+ +ID AL LKKRVE Sbjct 120 MIKRKAEKVIIDRALAGLKKRVE 142 >gi|297194841|ref|ZP_06912239.1| cyclase [Streptomyces pristinaespiralis ATCC 25486] gi|197720697|gb|EDY64605.1| cyclase [Streptomyces pristinaespiralis ATCC 25486] Length=149 Score = 144 bits (362), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 70/145 (49%), Positives = 99/145 (69%), Gaps = 3/145 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I IDA P EVM I+D YP+W E KE E+L D EG ++ R+++DA Sbjct 1 MAEHTSSSITIDAAPAEVMGVISDFTRYPEWTGEVKEAEVLATDAEGRAEQVRLVLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSG--TEVTYELAVDLAVPM 118 KD ++Y W +SWTL S +L++++G+YRL+P G G TEVTY+L VD+ +PM Sbjct 61 IKDDHTLAYTW-HGANEVSWTLVKSQMLRAIDGSYRLSPVGGGDRTEVTYQLTVDVKIPM 119 Query 119 IGMLKRKAERRLIDGALKDLKKRVE 143 +GM+KRKAE+ +ID AL LKKRVE Sbjct 120 LGMIKRKAEKVIIDRALAGLKKRVE 144 >gi|302534007|ref|ZP_07286349.1| cyclase [Streptomyces sp. C] gi|302442902|gb|EFL14718.1| cyclase [Streptomyces sp. C] Length=147 Score = 143 bits (361), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 72/144 (50%), Positives = 99/144 (69%), Gaps = 2/144 (1%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I IDA P +VM IAD YP+W E KE E+L D EG ++ R+L+DA Sbjct 1 MAEHTSSSITIDASPADVMAVIADFARYPEWTGEVKEAEVLATDAEGRAEKVRLLLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAP-KGSGTEVTYELAVDLAVPMI 119 KD ++Y W + +SWTL+ S +L+ L+G+YRLAP G TEVTY+L VD+ +PM+ Sbjct 61 IKDDHTLAYTW-KGADEVSWTLDKSQMLRQLDGSYRLAPLDGGRTEVTYQLTVDVKIPML 119 Query 120 GMLKRKAERRLIDGALKDLKKRVE 143 GM+KRKAE+ +ID AL LKKRVE Sbjct 120 GMIKRKAEKVIIDRALAGLKKRVE 143 >gi|329940989|ref|ZP_08290269.1| hypothetical protein SGM_5761 [Streptomyces griseoaurantiacus M045] gi|329300283|gb|EGG44181.1| hypothetical protein SGM_5761 [Streptomyces griseoaurantiacus M045] Length=146 Score = 143 bits (360), Expect = 9e-33, Method: Compositional matrix adjust. Identities = 70/144 (49%), Positives = 100/144 (70%), Gaps = 2/144 (1%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM IAD YP W E KE E+L D +G ++ R++MDA Sbjct 1 MAEHTSSSITIEAAPADVMGVIADFARYPDWTGEVKEAEVLATDGQGRAEQVRLVMDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSG-TEVTYELAVDLAVPMI 119 KD +++Y W + + +SWTL S +L+SL+G+Y L P G+G TEVTY+L VD+ +PM+ Sbjct 61 IKDDQVLAYTWGSEHE-VSWTLVKSQMLRSLDGSYLLKPAGTGATEVTYQLTVDVKIPML 119 Query 120 GMLKRKAERRLIDGALKDLKKRVE 143 GM+KRKAE+ +ID AL LKKRVE Sbjct 120 GMIKRKAEKVIIDRALAGLKKRVE 143 >gi|111018132|ref|YP_701104.1| hypothetical protein RHA1_ro01119 [Rhodococcus jostii RHA1] gi|110817662|gb|ABG92946.1| conserved hypothetical protein [Rhodococcus jostii RHA1] Length=145 Score = 142 bits (359), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 71/143 (50%), Positives = 97/143 (68%), Gaps = 1/143 (0%) Query 3 DKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAIFK 62 ++T ++I I+A P VM IAD +AYP W++ K VE++E G R R ++DA + K Sbjct 3 ERTKRSISIEAPPARVMDVIADFDAYPAWVTAAKSVEVMEPGKGGRADRVRFVLDAGMVK 62 Query 63 DTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPK-GSGTEVTYELAVDLAVPMIGM 121 DT ++ Y+W D +S+SW LES + KS G+Y L + G GT VTYEL VDL +PMIG+ Sbjct 63 DTYVLRYDWAPDGKSVSWELESGEIQKSQFGSYVLEDEPGGGTTVTYELTVDLTIPMIGL 122 Query 122 LKRKAERRLIDGALKDLKKRVEG 144 KRKAE+ + D ALK+LKKRVEG Sbjct 123 FKRKAEKAITDTALKELKKRVEG 145 >gi|29832613|ref|NP_827247.1| hypothetical protein SAV_6071 [Streptomyces avermitilis MA-4680] gi|29609733|dbj|BAC73782.1| hypothetical protein [Streptomyces avermitilis MA-4680] Length=147 Score = 142 bits (357), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 70/144 (49%), Positives = 100/144 (70%), Gaps = 2/144 (1%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM+ IAD YP W E KE E+L D +G ++ R++MDA Sbjct 1 MAEHTSSSIMIEAAPADVMEVIADFARYPDWTGEVKEAEVLGTDGQGRAEQVRLVMDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGS-GTEVTYELAVDLAVPMI 119 KD +++Y W D + +SW+L S +L+SL+G+Y L P GS TEVTY+L VD+ +PM+ Sbjct 61 IKDDQVLAYTWTGDHE-VSWSLVKSQMLRSLDGSYLLKPAGSDATEVTYQLTVDVKIPML 119 Query 120 GMLKRKAERRLIDGALKDLKKRVE 143 GM+KRKAE+ +ID AL LKKRVE Sbjct 120 GMIKRKAEKVIIDRALAGLKKRVE 143 >gi|226360261|ref|YP_002778039.1| hypothetical protein ROP_08470 [Rhodococcus opacus B4] gi|226238746|dbj|BAH49094.1| hypothetical protein [Rhodococcus opacus B4] Length=145 Score = 142 bits (357), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 72/144 (50%), Positives = 96/144 (67%), Gaps = 3/144 (2%) Query 3 DKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAIFK 62 ++T ++I I+A P VM IAD AYP W++ K VE++E G R R ++DA + K Sbjct 3 ERTKRSISIEAPPARVMDVIADFNAYPAWVAAAKSVEVMEPGKNGRADRVRFVLDAGMVK 62 Query 63 DTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRL--APKGSGTEVTYELAVDLAVPMIG 120 DT ++ Y+W D +S+SW LES + KS G+Y L P G GT VTYEL VDL +PMIG Sbjct 63 DTYVLRYDWAPDGKSVSWELESGEIQKSQFGSYVLEDEPDG-GTTVTYELTVDLTIPMIG 121 Query 121 MLKRKAERRLIDGALKDLKKRVEG 144 + KRKAE+ + D ALK+LKKRVEG Sbjct 122 LFKRKAEKAITDTALKELKKRVEG 145 >gi|291440137|ref|ZP_06579527.1| cyclase/dehydrase [Streptomyces ghanaensis ATCC 14672] gi|291343032|gb|EFE69988.1| cyclase/dehydrase [Streptomyces ghanaensis ATCC 14672] Length=147 Score = 141 bits (356), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 71/144 (50%), Positives = 99/144 (69%), Gaps = 2/144 (1%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM IAD YP W E KE E+LE D++G ++ R++MDA Sbjct 1 MAEHTSSSITIEAAPADVMGVIADFARYPDWTGEVKEAEVLETDEQGRAEQVRLVMDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSG-TEVTYELAVDLAVPMI 119 KD ++Y W + + +SWTL S +L+SL+G+Y L P G G TEVTY L VD+ +PM+ Sbjct 61 IKDDQTLAYTWTGEHE-VSWTLVKSQMLRSLDGSYLLEPAGPGTTEVTYRLTVDVKIPML 119 Query 120 GMLKRKAERRLIDGALKDLKKRVE 143 GM+KRKAE+ +ID AL LKKRVE Sbjct 120 GMIKRKAEKVIIDRALAGLKKRVE 143 >gi|254382641|ref|ZP_04997999.1| conserved hypothetical protein [Streptomyces sp. Mg1] gi|194341544|gb|EDX22510.1| conserved hypothetical protein [Streptomyces sp. Mg1] Length=147 Score = 141 bits (356), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 72/145 (50%), Positives = 96/145 (67%), Gaps = 3/145 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T +I IDA P +VM IAD YP+W E KE E+L D EG + R+L+DA Sbjct 1 MAEHTKSSITIDAAPADVMAVIADFARYPEWTGEVKEAEVLGTDAEGRASKVRLLLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAP--KGSGTEVTYELAVDLAVPM 118 KD ++Y W +SWTL+ S +L+ L+G+YRLAP G TEVTY+L VD+ +PM Sbjct 61 IKDDHTLAYSWA-GTDEVSWTLDKSQMLRQLDGSYRLAPLEGGKRTEVTYQLTVDVKIPM 119 Query 119 IGMLKRKAERRLIDGALKDLKKRVE 143 +GM+KRKAE+ +ID AL LKKRVE Sbjct 120 LGMIKRKAEKVIIDRALAGLKKRVE 144 >gi|345014505|ref|YP_004816859.1| cyclase/dehydrase [Streptomyces violaceusniger Tu 4113] gi|344040854|gb|AEM86579.1| cyclase/dehydrase [Streptomyces violaceusniger Tu 4113] Length=146 Score = 141 bits (356), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 70/145 (49%), Positives = 101/145 (70%), Gaps = 3/145 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM+ IAD + YP+W E KE +IL DD G ++ RML+DA Sbjct 1 MAEHTSSSITIEAAPADVMEVIADFDRYPEWSGEVKEADILTKDDRGRAEQVRMLLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPK--GSGTEVTYELAVDLAVPM 118 KD + Y W D Q ++W+L S +L++L+G+YRL+ + G TEVTY+L VD+ +PM Sbjct 61 IKDDYTLQYSWTGDDQ-VNWSLVKSQMLRTLDGSYRLSARDGGKSTEVTYQLTVDVKIPM 119 Query 119 IGMLKRKAERRLIDGALKDLKKRVE 143 +GM+KRKAE+ +ID AL LKKRVE Sbjct 120 LGMIKRKAEKVIIDRALAGLKKRVE 144 >gi|320011240|gb|ADW06090.1| Polyketide cyclase/dehydrase [Streptomyces flavogriseus ATCC 33331] Length=149 Score = 141 bits (356), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 70/145 (49%), Positives = 101/145 (70%), Gaps = 3/145 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM IAD YP+W E KE EIL DD+G ++ R+++DA Sbjct 1 MAEHTSSSITIEAAPADVMGVIADFARYPEWTGEVKEAEILATDDQGRAEQVRLVLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSG--TEVTYELAVDLAVPM 118 KD ++SY W + + + WTL S +L++L+G+Y LAP G G T+VTY LAVD+ +P+ Sbjct 61 IKDDHVLSYTWNSEYE-VGWTLVKSQMLRALDGSYALAPLGDGDRTQVTYRLAVDVKIPL 119 Query 119 IGMLKRKAERRLIDGALKDLKKRVE 143 +GM+KRKAE+ +ID AL LKKRVE Sbjct 120 LGMIKRKAEKVIIDRALAGLKKRVE 144 >gi|239987099|ref|ZP_04707763.1| hypothetical protein SrosN1_07317 [Streptomyces roseosporus NRRL 11379] gi|291444054|ref|ZP_06583444.1| cyclase/dehydrase [Streptomyces roseosporus NRRL 15998] gi|291347001|gb|EFE73905.1| cyclase/dehydrase [Streptomyces roseosporus NRRL 15998] Length=149 Score = 140 bits (354), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 69/145 (48%), Positives = 100/145 (69%), Gaps = 3/145 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM IAD YP+W E KE E+L DD+G ++ R+++DA Sbjct 1 MAEHTSSSITIEAAPADVMGVIADFARYPEWTGEVKEAEVLSTDDQGRAEQVRLVLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSG--TEVTYELAVDLAVPM 118 KD +++Y W + + +SW+L S +L+SL+GTY L P G TEVTY LAVD+ +P+ Sbjct 61 IKDDHVLAYTWTGENE-VSWSLVKSQMLRSLDGTYALTPLAGGERTEVTYRLAVDVKIPL 119 Query 119 IGMLKRKAERRLIDGALKDLKKRVE 143 +GM+KRKAE+ +ID AL LKKRVE Sbjct 120 LGMIKRKAEKVIIDRALAGLKKRVE 144 >gi|302550842|ref|ZP_07303184.1| cyclase/dehydrase [Streptomyces viridochromogenes DSM 40736] gi|302468460|gb|EFL31553.1| cyclase/dehydrase [Streptomyces viridochromogenes DSM 40736] Length=145 Score = 140 bits (353), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 70/144 (49%), Positives = 99/144 (69%), Gaps = 2/144 (1%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM IAD YP W E KE E+L+ D +G ++ R++MDA Sbjct 1 MAEHTSSSITIEAAPADVMAVIADFARYPDWTGEVKEAEVLKTDAQGRAEQVRLVMDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGS-GTEVTYELAVDLAVPMI 119 KD ++ Y W + + +SWTL S +L+SL+G+Y L P G+ GTEVTY L VD+ +PM+ Sbjct 61 IKDDQVLGYTWTGENE-VSWTLVKSQMLRSLDGSYILKPAGAGGTEVTYVLTVDVKIPML 119 Query 120 GMLKRKAERRLIDGALKDLKKRVE 143 GM+KRKAE+ +ID AL LKKRVE Sbjct 120 GMIKRKAEKVIIDRALAGLKKRVE 143 >gi|271964210|ref|YP_003338406.1| hypothetical protein Sros_2698 [Streptosporangium roseum DSM 43021] gi|270507385|gb|ACZ85663.1| hypothetical protein Sros_2698 [Streptosporangium roseum DSM 43021] Length=145 Score = 139 bits (350), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 69/144 (48%), Positives = 93/144 (65%), Gaps = 2/144 (1%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +AD+TT +I I A +M IAD +YP+W + K +L AD +G P R +DA + Sbjct 1 MADRTTSSITIGAGRSPIMTVIADFASYPEWAGQVKSARVLSADADGRPATVRFALDAGV 60 Query 61 FKDTLIMSYEWPEDRQSLSWTL-ESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMI 119 D ++Y W S+ W + E+ ++ L G+YRLA +G GTEVTYELAVDL VPMI Sbjct 61 ISDEYTLAYTW-HGEDSVDWNIAEAGKMVSGLTGSYRLADEGGGTEVTYELAVDLKVPMI 119 Query 120 GMLKRKAERRLIDGALKDLKKRVE 143 GM++RKAE+ +ID ALK LKKRVE Sbjct 120 GMIRRKAEKVIIDTALKGLKKRVE 143 >gi|337765268|emb|CCB73977.1| conserved protein of unknown function [Streptomyces cattleya NRRL 8057] Length=158 Score = 139 bits (350), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 69/145 (48%), Positives = 99/145 (69%), Gaps = 3/145 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T +I I+A P EVM+ IAD YP+W E K+ EIL+ D++G +R R+++DA Sbjct 1 MAEHTRSSITIEAAPAEVMRVIADFARYPEWTGEVKQAEILDTDEQGRARRVRLVLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAP--KGSGTEVTYELAVDLAVPM 118 KD ++Y W Q +SW+L S +L++L+G+Y L P G TEVTY+L VD+ +PM Sbjct 61 IKDDHTLAYTWGGPDQ-VSWSLVKSQMLRTLDGSYTLVPVQGGHRTEVTYQLTVDVKIPM 119 Query 119 IGMLKRKAERRLIDGALKDLKKRVE 143 +GM+KRKAE+ +ID AL LKKRVE Sbjct 120 LGMIKRKAEKVIIDRALAGLKKRVE 144 >gi|254393052|ref|ZP_05008214.1| cyclase/dehydrase [Streptomyces clavuligerus ATCC 27064] gi|294812180|ref|ZP_06770823.1| Cyclase/dehydrase [Streptomyces clavuligerus ATCC 27064] gi|326440664|ref|ZP_08215398.1| hypothetical protein SclaA2_06338 [Streptomyces clavuligerus ATCC 27064] gi|197706701|gb|EDY52513.1| cyclase/dehydrase [Streptomyces clavuligerus ATCC 27064] gi|294324779|gb|EFG06422.1| Cyclase/dehydrase [Streptomyces clavuligerus ATCC 27064] Length=149 Score = 139 bits (350), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 68/145 (47%), Positives = 101/145 (70%), Gaps = 3/145 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM I+D + YP+W E K+ E+L D++G ++ R+++DA Sbjct 1 MAEHTSSSITIEAAPADVMGVISDFDRYPEWTGEVKQAEVLSRDEQGRAEQVRLVLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSG--TEVTYELAVDLAVPM 118 KD ++Y W E ++SWTL S +L++L+G+Y LAP G G TEVTY L VD+ +PM Sbjct 61 IKDDHTLAYSW-EGADTVSWTLVKSQMLRALDGSYTLAPVGGGDRTEVTYTLTVDVKIPM 119 Query 119 IGMLKRKAERRLIDGALKDLKKRVE 143 +GM+KRKAE+ +ID AL LKKRVE Sbjct 120 LGMIKRKAEKVIIDRALDGLKKRVE 144 >gi|344999162|ref|YP_004802016.1| cyclase/dehydrase [Streptomyces sp. SirexAA-E] gi|344314788|gb|AEN09476.1| cyclase/dehydrase [Streptomyces sp. SirexAA-E] Length=149 Score = 139 bits (349), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 70/145 (49%), Positives = 100/145 (69%), Gaps = 3/145 (2%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +A+ T+ +I I+A P +VM IAD YP+W E KE EIL DD G ++ R+++DA Sbjct 1 MAEHTSSSITIEAAPADVMDVIADFARYPEWTGEVKEAEILATDDLGRAEQVRLVLDAGA 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSG--TEVTYELAVDLAVPM 118 KD +++Y W + + + WTL S +L++L+G+Y LAP G G TEVTY LAVD+ +P+ Sbjct 61 IKDDHVLAYTWNSEYE-VDWTLVKSQMLRALDGSYALAPLGDGDRTEVTYRLAVDVKIPL 119 Query 119 IGMLKRKAERRLIDGALKDLKKRVE 143 +GM+KRKAE+ +ID AL LKKRVE Sbjct 120 LGMIKRKAEKVIIDRALAGLKKRVE 144 >gi|326333547|ref|ZP_08199787.1| cyclase/dehydrase [Nocardioidaceae bacterium Broad-1] gi|325948656|gb|EGD40756.1| cyclase/dehydrase [Nocardioidaceae bacterium Broad-1] Length=143 Score = 139 bits (349), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 69/143 (49%), Positives = 99/143 (70%), Gaps = 1/143 (0%) Query 1 VADKTTQTIYIDADPGEVMKAIADIEAYPQWISEYKEVEILEADDEGYPKRARMLMDAAI 60 +AD+TT TI I+A P VM IAD ++YP W +EV +LE +G ++ R ++D A Sbjct 1 MADQTTSTIVIEAAPSAVMAVIADFKSYPAWAKGMQEVSVLETGVDGRAEQVRFVLDVAP 60 Query 61 FKDTLIMSYEWPEDRQSLSWTLESSSLLKSLEGTYRLAPKGSGTEVTYELAVDLAVPMIG 120 KD ++Y+W +DRQ ++W+L +LL+S++G Y L G TEVTY LA+DL++P+IG Sbjct 61 IKDEYTLAYDWDDDRQ-VTWSLVKGNLLRSMDGAYVLRDLGGRTEVTYRLALDLSIPLIG 119 Query 121 MLKRKAERRLIDGALKDLKKRVE 143 MLKRK E+ LID AL+ LK+RVE Sbjct 120 MLKRKGEKVLIDTALRGLKQRVE 142 Lambda K H 0.314 0.132 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 128702269584 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40