BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2214c Length=592 Score E Sequences producing significant alignments: (Bits) Value gi|15609351|ref|NP_216730.1| short chain dehydrogenase [Mycobact... 1197 0.0 gi|339295128|gb|AEJ47239.1| short chain dehydrogenase [Mycobacte... 1191 0.0 gi|308404466|ref|ZP_07493986.2| short-chain type dehydrogenase e... 1183 0.0 gi|240168278|ref|ZP_04746937.1| short chain dehydrogenase [Mycob... 1020 0.0 gi|118618858|ref|YP_907190.1| short chain dehydrogenase [Mycobac... 1016 0.0 gi|183983250|ref|YP_001851541.1| short-chain dehydrogenase EphD ... 1014 0.0 gi|15827387|ref|NP_301650.1| short chain dehydrogenase [Mycobact... 991 0.0 gi|296166091|ref|ZP_06848536.1| short-chain dehydrogenase/reduct... 984 0.0 gi|254821886|ref|ZP_05226887.1| short chain dehydrogenase [Mycob... 982 0.0 gi|342857219|ref|ZP_08713875.1| short chain dehydrogenase [Mycob... 972 0.0 gi|118464693|ref|YP_881479.1| short chain dehydrogenase [Mycobac... 955 0.0 gi|254774947|ref|ZP_05216463.1| short chain dehydrogenase [Mycob... 952 0.0 gi|336461814|gb|EGO40670.1| short-chain dehydrogenase of unknown... 942 0.0 gi|41408053|ref|NP_960889.1| short chain dehydrogenase [Mycobact... 940 0.0 gi|108800277|ref|YP_640474.1| short chain dehydrogenase [Mycobac... 738 0.0 gi|118468842|ref|YP_888558.1| short chain dehydrogenase [Mycobac... 687 0.0 gi|145223524|ref|YP_001134202.1| short chain dehydrogenase [Myco... 563 3e-158 gi|169631098|ref|YP_001704747.1| short chain dehydrogenase [Myco... 530 3e-148 gi|317507424|ref|ZP_07965157.1| short chain dehydrogenase [Segni... 526 4e-147 gi|343928526|ref|ZP_08767973.1| putative peptidase S33 family pr... 513 3e-143 gi|317505975|ref|ZP_07963807.1| short chain dehydrogenase [Segni... 512 7e-143 gi|296394715|ref|YP_003659599.1| short-chain dehydrogenase/reduc... 484 3e-134 gi|343927405|ref|ZP_08766878.1| putative peptidase S33 family pr... 438 1e-120 gi|254428270|ref|ZP_05041977.1| oxidoreductase, short chain dehy... 436 5e-120 gi|311899724|dbj|BAJ32132.1| putative peptidase S33 family prote... 436 7e-120 gi|302530522|ref|ZP_07282864.1| short-chain dehydrogenase/reduct... 433 5e-119 gi|134100092|ref|YP_001105753.1| short chain dehydrogenase [Sacc... 431 2e-118 gi|271962091|ref|YP_003336287.1| short-chain dehydrogenase/reduc... 430 3e-118 gi|291002914|ref|ZP_06560887.1| short chain dehydrogenase [Sacch... 430 4e-118 gi|256397823|ref|YP_003119387.1| short chain dehydrogenase [Cate... 429 8e-118 gi|309782121|ref|ZP_07676851.1| oxidoreductase, short-chain dehy... 426 8e-117 gi|187928384|ref|YP_001898871.1| short chain dehydrogenase [Rals... 425 9e-117 gi|326384658|ref|ZP_08206336.1| short chain dehydrogenase [Gordo... 422 6e-116 gi|120404547|ref|YP_954376.1| short chain dehydrogenase [Mycobac... 422 7e-116 gi|241662960|ref|YP_002981320.1| short chain dehydrogenase [Rals... 422 7e-116 gi|290959066|ref|YP_003490248.1| oxidoreductase [Streptomyces sc... 422 8e-116 gi|302535638|ref|ZP_07287980.1| short chain dehydrogenase [Strep... 421 2e-115 gi|206588570|emb|CAQ35533.1| alpha/beta hydrolase fold;short-cha... 420 4e-115 gi|336177893|ref|YP_004583268.1| Estradiol 17-beta-dehydrogenase... 420 4e-115 gi|110835557|ref|YP_694416.1| short chain dehydrogenase [Alcaniv... 420 4e-115 gi|254384844|ref|ZP_05000181.1| short chain dehydrogenase [Strep... 419 9e-115 gi|29830795|ref|NP_825429.1| short chain dehydrogenase [Streptom... 417 3e-114 gi|21222359|ref|NP_628138.1| short chain dehydrogenase [Streptom... 415 1e-113 gi|83749781|ref|ZP_00946755.1| Short chain dehydrogenase [Ralsto... 415 1e-113 gi|334196045|gb|AEG69230.1| 3-ketoacyl-(acyl-carrier-protein) re... 415 2e-113 gi|291438586|ref|ZP_06577976.1| short chain dehydrogenase [Strep... 414 3e-113 gi|289770441|ref|ZP_06529819.1| short chain dehydrogenase [Strep... 413 4e-113 gi|337767190|emb|CCB75901.1| putative oxidoreductase ephD [Strep... 411 2e-112 gi|172063922|ref|YP_001811573.1| short chain dehydrogenase [Burk... 408 2e-111 gi|115359139|ref|YP_776277.1| short chain dehydrogenase [Burkhol... 407 4e-111 >gi|15609351|ref|NP_216730.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|15841705|ref|NP_336742.1| short chain dehydrogenase [Mycobacterium tuberculosis CDC1551] gi|31793393|ref|NP_855886.1| short chain dehydrogenase [Mycobacterium bovis AF2122/97] 78 more sequence titles Length=592 Score = 1197 bits (3096), Expect = 0.0, Method: Compositional matrix adjust. Identities = 592/592 (100%), Positives = 592/592 (100%), Gaps = 0/592 (0%) Query 1 MPATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVR 60 MPATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVR Sbjct 1 MPATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVR 60 Query 61 YDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPG 120 YDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPG Sbjct 61 YDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPG 120 Query 121 ASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPL 180 ASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPL Sbjct 121 ASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPL 180 Query 181 LLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPI 240 LLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPI Sbjct 181 LLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPI 240 Query 241 VDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADL 300 VDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADL Sbjct 241 VDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADL 300 Query 301 ADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEAT 360 ADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEAT Sbjct 301 ADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEAT 360 Query 361 VKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDT 420 VKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDT Sbjct 361 VKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDT 420 Query 421 PAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAA 480 PAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAA Sbjct 421 PAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAA 480 Query 481 TYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFAL 540 TYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFAL Sbjct 481 TYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFAL 540 Query 541 RSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 RSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI Sbjct 541 RSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 >gi|339295128|gb|AEJ47239.1| short chain dehydrogenase [Mycobacterium tuberculosis CCDC5079] Length=594 Score = 1191 bits (3082), Expect = 0.0, Method: Compositional matrix adjust. Identities = 590/590 (100%), Positives = 590/590 (100%), Gaps = 0/590 (0%) Query 3 ATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYD 62 ATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYD Sbjct 5 ATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYD 64 Query 63 NRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGAS 122 NRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGAS Sbjct 65 NRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGAS 124 Query 123 DRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLL 182 DRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLL Sbjct 125 DRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLL 184 Query 183 RVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVD 242 RVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVD Sbjct 185 RVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVD 244 Query 243 VPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLAD 302 VPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLAD Sbjct 245 VPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLAD 304 Query 303 GKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVK 362 GKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVK Sbjct 305 GKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVK 364 Query 363 DTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPA 422 DTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPA Sbjct 365 DTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPA 424 Query 423 EQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATY 482 EQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATY Sbjct 425 EQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATY 484 Query 483 MFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRS 542 MFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRS Sbjct 485 MFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRS 544 Query 543 YGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 YGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI Sbjct 545 YGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 594 >gi|308404466|ref|ZP_07493986.2| short-chain type dehydrogenase ephD [Mycobacterium tuberculosis SUMu012] gi|308365581|gb|EFP54432.1| short-chain type dehydrogenase ephD [Mycobacterium tuberculosis SUMu012] gi|323719114|gb|EGB28259.1| short-chain type dehydrogenase ephD [Mycobacterium tuberculosis CDC1551A] Length=586 Score = 1183 bits (3061), Expect = 0.0, Method: Compositional matrix adjust. Identities = 586/586 (100%), Positives = 586/586 (100%), Gaps = 0/586 (0%) Query 7 MSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGV 66 MSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGV Sbjct 1 MSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGV 60 Query 67 GRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVA 126 GRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVA Sbjct 61 GRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVA 120 Query 127 SFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVAL 186 SFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVAL Sbjct 121 SFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVAL 180 Query 187 SSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQ 246 SSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQ Sbjct 181 SSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQ 240 Query 247 LIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQP 306 LIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQP Sbjct 241 LIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQP 300 Query 307 SRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAA 366 SRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAA Sbjct 301 SRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAA 360 Query 367 EIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFD 426 EIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFD Sbjct 361 EIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFD 420 Query 427 RVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSD 486 RVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSD Sbjct 421 RVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSD 480 Query 487 CLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPD 546 CLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPD Sbjct 481 CLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPD 540 Query 547 KVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 KVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI Sbjct 541 KVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 586 >gi|240168278|ref|ZP_04746937.1| short chain dehydrogenase [Mycobacterium kansasii ATCC 12478] Length=594 Score = 1020 bits (2637), Expect = 0.0, Method: Compositional matrix adjust. Identities = 500/594 (85%), Positives = 538/594 (91%), Gaps = 2/594 (0%) Query 1 MPATQQM-SRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIV 59 MPA QQ R VDS DG RIAVY EGNPDGP VVLVHGFPDSHVLWDGVVP LA+RFR++ Sbjct 1 MPAAQQAPQRFVDSADGARIAVYEEGNPDGPAVVLVHGFPDSHVLWDGVVPRLAQRFRVI 60 Query 60 RYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRP 119 RYDNRGVG SS PKP+SAYTMA FADDF AVI +L+PG VHV+ HDWGSVG+WEYL RP Sbjct 61 RYDNRGVGLSSAPKPVSAYTMACFADDFAAVIDQLTPGRRVHVMGHDWGSVGIWEYLTRP 120 Query 120 GASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAP 179 GA DRVASFTSVSGPSQ+ LV+YV+GGLRRPWRPR FLR+++Q LRLSYMALFSVPVVAP Sbjct 121 GAGDRVASFTSVSGPSQEQLVDYVWGGLRRPWRPRRFLRSLAQALRLSYMALFSVPVVAP 180 Query 180 LLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIP 239 L+LRVALS AAVRRNMV +IP DQIHHS+ L DAA SVKTYPANYFR+FS RR R I Sbjct 181 LILRVALSLAAVRRNMVDNIPADQIHHSDNLPSDAARSVKTYPANYFRAFSRQRRSRGIT 240 Query 240 IVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD 299 ++ VPVQLIVN+QDPYVRPYGYD+TARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD AD Sbjct 241 VIGVPVQLIVNTQDPYVRPYGYDETARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDIAD 300 Query 300 LADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEA 359 +G PSRALLRAQVGRPR +FGD LV+VTGAGSGIGRETALAFAREGAE+VISDIDEA Sbjct 301 FVEGNPPSRALLRAQVGRPRKHFGDILVAVTGAGSGIGRETALAFAREGAEVVISDIDEA 360 Query 360 TVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLD 419 TVKDTAAEIAARGG+A+PYVLDVSDAEAVEAFAE+VS HGVPDIVVNNAGIGQAGRFLD Sbjct 361 TVKDTAAEIAARGGVAHPYVLDVSDAEAVEAFAEQVSTRHGVPDIVVNNAGIGQAGRFLD 420 Query 420 TPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 479 TPAEQFDRVLAVNLGGVVNGCR+FG+RLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA Sbjct 421 TPAEQFDRVLAVNLGGVVNGCRSFGRRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 480 Query 480 ATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAP-GTDEEKIDGRRGQIDKMF 538 ATYMFSDCLRAELDAAGVGLTT+CPGVIDTNI+A T F P G EE+++GRR Q+DKMF Sbjct 481 ATYMFSDCLRAELDAAGVGLTTVCPGVIDTNIIAATRFDTPFGKGEEQVEGRRSQLDKMF 540 Query 539 ALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 ALR YGPDKVA AIVSAVKK KPIRPVAPEAYALYGISRVLPQALRSTAR+RVI Sbjct 541 ALRHYGPDKVAHAIVSAVKKNKPIRPVAPEAYALYGISRVLPQALRSTARMRVI 594 >gi|118618858|ref|YP_907190.1| short chain dehydrogenase [Mycobacterium ulcerans Agy99] gi|118570968|gb|ABL05719.1| short-chain dehydrogenase EphD [Mycobacterium ulcerans Agy99] Length=594 Score = 1016 bits (2628), Expect = 0.0, Method: Compositional matrix adjust. Identities = 497/594 (84%), Positives = 541/594 (92%), Gaps = 2/594 (0%) Query 1 MPATQQM-SRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIV 59 MPAT+Q + VDS GVRIAVY EGNPD PTVVLVHGFPDSHVLWDGVVP LAERFRI+ Sbjct 1 MPATKQAPQQFVDSAGGVRIAVYEEGNPDSPTVVLVHGFPDSHVLWDGVVPRLAERFRIL 60 Query 60 RYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRP 119 RYDNRGVG SS PK +SAYT A ADDF AVI LSPG+PVHVL HDWGSV +W+YL R Sbjct 61 RYDNRGVGLSSAPKAVSAYTTACLADDFAAVIEALSPGQPVHVLGHDWGSVAIWDYLTRS 120 Query 120 GASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAP 179 GA+DRVASFTSVSGPSQD LVNY++GGLR+PWRP+TF RA++Q LRLSYMALFSVPV+AP Sbjct 121 GAADRVASFTSVSGPSQDQLVNYIFGGLRQPWRPKTFARALTQALRLSYMALFSVPVLAP 180 Query 180 LLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIP 239 L+LR LS A+VRRNMV ++P+DQIHHS+ LA DAA+SVKTYPANYFR+FS R R +P Sbjct 181 LVLRATLSRASVRRNMVDNLPLDQIHHSDNLASDAANSVKTYPANYFRAFSRQSRTRGVP 240 Query 240 IVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD 299 ++DVPVQLIVN++DPYVRPYGYD+TARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD Sbjct 241 VIDVPVQLIVNTKDPYVRPYGYDETARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD 300 Query 300 LADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEA 359 L DGK PSRALLRAQVGRPR YFGDTLV+VTGAGSGIGRETALAFAREGAE+V+SDIDEA Sbjct 301 LVDGKPPSRALLRAQVGRPRKYFGDTLVAVTGAGSGIGRETALAFAREGAEVVLSDIDEA 360 Query 360 TVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLD 419 TVKDTAAEIAARGG+A+PYVLDVSD EAVEAFA++VSA HG+PDIVVNNAG+GQAGRFLD Sbjct 361 TVKDTAAEIAARGGVAHPYVLDVSDTEAVEAFADQVSATHGLPDIVVNNAGVGQAGRFLD 420 Query 420 TPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 479 TPAEQFDRVL VNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA Sbjct 421 TPAEQFDRVLDVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 480 Query 480 ATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHA-PGTDEEKIDGRRGQIDKMF 538 AT+MFSDCLRAELDAA VGLTTICPGVI+TNIV TT F A PG +++DGRRGQIDKMF Sbjct 481 ATFMFSDCLRAELDAADVGLTTICPGVINTNIVNTTRFDAPPGKGGDQLDGRRGQIDKMF 540 Query 539 ALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 ALRSYGPDKVA AIVSAVKK KPIRPVAPEAYALYGISRVLP ALRSTAR+RVI Sbjct 541 ALRSYGPDKVAKAIVSAVKKNKPIRPVAPEAYALYGISRVLPPALRSTARMRVI 594 >gi|183983250|ref|YP_001851541.1| short-chain dehydrogenase EphD [Mycobacterium marinum M] gi|183176576|gb|ACC41686.1| short-chain dehydrogenase EphD [Mycobacterium marinum M] Length=594 Score = 1014 bits (2622), Expect = 0.0, Method: Compositional matrix adjust. Identities = 497/594 (84%), Positives = 541/594 (92%), Gaps = 2/594 (0%) Query 1 MPATQQM-SRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIV 59 M AT+Q + VDS GVRIAVY EGNPDGPTVVLVHGFPDSHVLWDGVVP LAERFRI+ Sbjct 1 MSATRQAPQQFVDSAGGVRIAVYEEGNPDGPTVVLVHGFPDSHVLWDGVVPRLAERFRIL 60 Query 60 RYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRP 119 RYDNRGVG SS PK +SAYT A ADDF AVI LSPG+PVHVL HDWGSV +WEYL R Sbjct 61 RYDNRGVGLSSAPKAVSAYTTACLADDFAAVIEALSPGQPVHVLGHDWGSVAIWEYLTRS 120 Query 120 GASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAP 179 GA+DRVASFTSVSGPSQD LVNY++GGLR+PWRP+TF RA++Q LRLSYMALFSVPV+AP Sbjct 121 GAADRVASFTSVSGPSQDQLVNYIFGGLRQPWRPKTFARALTQALRLSYMALFSVPVLAP 180 Query 180 LLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIP 239 L+LR LS A+VRRNMV ++P+D+IHHS+ LA DAA+SVKTYPANYFR+FS R R +P Sbjct 181 LVLRATLSRASVRRNMVDNLPLDRIHHSDNLASDAANSVKTYPANYFRAFSRQSRTRGVP 240 Query 240 IVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD 299 ++DVPVQLIVN++DPYVRPYGYD+TARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD Sbjct 241 VIDVPVQLIVNTKDPYVRPYGYDETARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD 300 Query 300 LADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEA 359 L DGK PSRALLRAQVGRPR YFGDTLV+VTGAGSGIGRETALAFAREGAE+V+SDIDEA Sbjct 301 LVDGKPPSRALLRAQVGRPRKYFGDTLVAVTGAGSGIGRETALAFAREGAEVVLSDIDEA 360 Query 360 TVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLD 419 TVKDTAAEIAARGG+A+PYVLDVSD EAVEAFA++VSA HG+PDIVVNNAG+GQAGRFLD Sbjct 361 TVKDTAAEIAARGGVAHPYVLDVSDTEAVEAFADQVSATHGLPDIVVNNAGVGQAGRFLD 420 Query 420 TPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 479 TPAEQFDRVL VNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA Sbjct 421 TPAEQFDRVLDVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 480 Query 480 ATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHA-PGTDEEKIDGRRGQIDKMF 538 AT+MFSDCLRAELDAA VGLTTICPGVI+TNIV TT F A PG +++DGRRGQIDKMF Sbjct 481 ATFMFSDCLRAELDAADVGLTTICPGVINTNIVNTTRFDAPPGKGGDQVDGRRGQIDKMF 540 Query 539 ALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 ALRSYGPDKVA AIVSAVKK KPIRPVAPEAYALYGISRVLP ALRSTAR+RVI Sbjct 541 ALRSYGPDKVAKAIVSAVKKNKPIRPVAPEAYALYGISRVLPPALRSTARMRVI 594 >gi|15827387|ref|NP_301650.1| short chain dehydrogenase [Mycobacterium leprae TN] gi|221229864|ref|YP_002503280.1| short chain dehydrogenase [Mycobacterium leprae Br4923] gi|2342610|emb|CAB11381.1| oxidoreductase [Mycobacterium leprae] gi|13092937|emb|CAC31243.1| putative oxidoreductase [Mycobacterium leprae] gi|219932971|emb|CAR70957.1| putative oxidoreductase [Mycobacterium leprae Br4923] Length=596 Score = 991 bits (2563), Expect = 0.0, Method: Compositional matrix adjust. Identities = 479/596 (81%), Positives = 524/596 (88%), Gaps = 4/596 (0%) Query 1 MPATQQMSRL----VDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERF 56 MPATQ + ++ V+SPDGVR+A+Y G P+GP +VLVHGFPDSHVLWDGVVPLLA+RF Sbjct 1 MPATQSIHKVPHQFVESPDGVRLAIYQSGQPEGPAIVLVHGFPDSHVLWDGVVPLLAKRF 60 Query 57 RIVRYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYL 116 RIVRYDNRGVG+SSVPKP+SAYTM FADDF AVI ELSP PVHVLAHDWGSVGVWEYL Sbjct 61 RIVRYDNRGVGQSSVPKPVSAYTMTRFADDFAAVIDELSPDRPVHVLAHDWGSVGVWEYL 120 Query 117 RRPGASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPV 176 R GASDRVASFTSVSGPSQD LV+Y+ GLRRPWRPRTF RA+SQ RL+YM LFS+PV Sbjct 121 SRSGASDRVASFTSVSGPSQDQLVDYILSGLRRPWRPRTFARAVSQLFRLTYMVLFSIPV 180 Query 177 VAPLLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGR 236 + P++L +ALSSA +RR MV +I DQIHHS TLARDAAHSVKTYPANYFR+FS RRG+ Sbjct 181 LVPMVLWIALSSATIRRTMVDNISTDQIHHSATLARDAAHSVKTYPANYFRAFSGRRRGK 240 Query 237 AIPIVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD 296 +P+V+VPVQLIVN+ D YVRPYGYD TARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD Sbjct 241 GVPVVNVPVQLIVNTMDRYVRPYGYDATARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHD 300 Query 297 FADLADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDI 356 ADL DGKQPSRALLRAQVGR R FGDTLVSVTGAGSGIGRETALA AR GAE+V+SDI Sbjct 301 LADLVDGKQPSRALLRAQVGRSRDTFGDTLVSVTGAGSGIGRETALALARRGAEVVVSDI 360 Query 357 DEATVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGR 416 DEA K+TAA+I A GG+AY Y LDVSDA AVEAFAE+VSA+HGVPDIVVNNAGIGQAGR Sbjct 361 DEAAAKNTAAQIVASGGVAYAYALDVSDAAAVEAFAEQVSAKHGVPDIVVNNAGIGQAGR 420 Query 417 FLDTPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCT 476 FLDTP E+FDRVLAVNLGGVVN CRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCT Sbjct 421 FLDTPPEEFDRVLAVNLGGVVNCCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCT 480 Query 477 SKAATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDK 536 SKAATYMFSDCLRAELDA GVGLTTICPGVIDTNI+ +T P +E++ RRGQ+D Sbjct 481 SKAATYMFSDCLRAELDAVGVGLTTICPGVIDTNIIQSTRIDTPTAKQERVRDRRGQLDM 540 Query 537 MFALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 MF LR YGPDKVAD I+SA+KK KPIRPVAPEAYALYGISRVLPQ LRSTAR+RVI Sbjct 541 MFRLRRYGPDKVADTILSAIKKNKPIRPVAPEAYALYGISRVLPQVLRSTARIRVI 596 >gi|296166091|ref|ZP_06848536.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898500|gb|EFG78061.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=591 Score = 984 bits (2544), Expect = 0.0, Method: Compositional matrix adjust. Identities = 484/593 (82%), Positives = 531/593 (90%), Gaps = 3/593 (0%) Query 1 MPATQQMSR-LVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIV 59 MPATQQ ++ VDS DG RIAVY EGNP+GPTVVLVHGFPDSHVLWDGVVPLLA+RFR++ Sbjct 1 MPATQQPTQHFVDSADGARIAVYEEGNPEGPTVVLVHGFPDSHVLWDGVVPLLADRFRVL 60 Query 60 RYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRP 119 RYDNRGVG SS PKP+SAY+M FADDF AV GELSPG PVHVLAHDWGSVGVW YL+RP Sbjct 61 RYDNRGVGASSAPKPVSAYSMDRFADDFAAVTGELSPGRPVHVLAHDWGSVGVWHYLKRP 120 Query 120 GASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAP 179 GA DRVA+FTSVSGPSQD LV+Y++ GLRRPWRPRTF+RAISQ LRL+YM FS+PVVAP Sbjct 121 GAGDRVATFTSVSGPSQDQLVDYIFSGLRRPWRPRTFVRAISQALRLTYMIFFSIPVVAP 180 Query 180 LLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIP 239 LLLR+ LS A+RRN V +IP +QIHHS LARDAA SVKTYPANYFRSFS RGR + Sbjct 181 LLLRLTLSIPALRRNAVDNIPAEQIHHSPQLARDAARSVKTYPANYFRSFSG--RGRGVH 238 Query 240 IVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD 299 +VDVPVQLIVN++D YVRPYGYD T R+VPRLWRRDI+AGHFSPMSHPQVMAAAVHDFAD Sbjct 239 VVDVPVQLIVNTRDKYVRPYGYDHTPRFVPRLWRRDIRAGHFSPMSHPQVMAAAVHDFAD 298 Query 300 LADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEA 359 LA+G PSRALLRAQVGRPRG FGDTLVSVTGAGSGIGRETA AFAREGAE+V+SDIDEA Sbjct 299 LAEGGPPSRALLRAQVGRPRGPFGDTLVSVTGAGSGIGRETAFAFAREGAELVVSDIDEA 358 Query 360 TVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLD 419 VK TAAEIA RGG+A+ YVLDVSDA AVEAFAERVSAEHGVPDIVVNNAGIGQAG FLD Sbjct 359 AVKATAAEIATRGGVAHAYVLDVSDAGAVEAFAERVSAEHGVPDIVVNNAGIGQAGGFLD 418 Query 420 TPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 479 TPAEQFDRVL VNLGGVVNGCR+F +R+VERGTGG+IVNVSSMAAYAPLQSL+AYCTSKA Sbjct 419 TPAEQFDRVLDVNLGGVVNGCRSFARRMVERGTGGYIVNVSSMAAYAPLQSLNAYCTSKA 478 Query 480 ATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFA 539 ATYMFSDCLRAELDAAGVGLTTICPGVIDTNI+ TT F AP E++DGRRGQ+ KMFA Sbjct 479 ATYMFSDCLRAELDAAGVGLTTICPGVIDTNIINTTRFDAPAGKGEQVDGRRGQLGKMFA 538 Query 540 LRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 LR YGPDKVA+AI+S+V+KKKPIRPVAPEAYALYG SR+ PQ LR+ AR+RVI Sbjct 539 LRHYGPDKVANAILSSVQKKKPIRPVAPEAYALYGFSRIAPQGLRNFARMRVI 591 >gi|254821886|ref|ZP_05226887.1| short chain dehydrogenase [Mycobacterium intracellulare ATCC 13950] Length=592 Score = 982 bits (2539), Expect = 0.0, Method: Compositional matrix adjust. Identities = 480/594 (81%), Positives = 529/594 (90%), Gaps = 4/594 (0%) Query 1 MPATQQMSR-LVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIV 59 MP +QQ+ R VDS DG RIAVY EGNP+GPT VLVHGFPDSHVLWDGVVPLLAERFRI+ Sbjct 1 MPPSQQLPRHFVDSADGARIAVYEEGNPEGPTAVLVHGFPDSHVLWDGVVPLLAERFRII 60 Query 60 RYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRP 119 RYDNRGVG SSVPK +SAY+M FA+DF AV GELSPG PVHVLAHDWGSVGVW YL+RP Sbjct 61 RYDNRGVGLSSVPKAVSAYSMDRFAEDFAAVTGELSPGAPVHVLAHDWGSVGVWHYLKRP 120 Query 120 GASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAP 179 GA DRVA+FTSVSGP+QD LV+Y++ GLR PWRPRTFLRA+SQ LR +YM LFS+PV+AP Sbjct 121 GAGDRVATFTSVSGPAQDQLVDYIFTGLRAPWRPRTFLRALSQALRFTYMLLFSIPVLAP 180 Query 180 LLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIP 239 L LR+ LS A+RRN V +IPV+QIHHS+ LARDAA SVKTYPANYFRSFS + G + Sbjct 181 LFLRLTLSVPALRRNAVDNIPVEQIHHSDKLARDAAQSVKTYPANYFRSFSGRKGG--VA 238 Query 240 IVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD 299 ++DVPVQLIVN++D YVRPYGYD T R+VPRLWRRDI+AGHFSPMSHPQVMAAAVHDFAD Sbjct 239 VIDVPVQLIVNTRDKYVRPYGYDHTPRFVPRLWRRDIRAGHFSPMSHPQVMAAAVHDFAD 298 Query 300 LADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEA 359 L +GKQPSRALLRAQ+GRPRG FGDTLVSVTGAGSGIGRETA AFAREGAE+VISDIDEA Sbjct 299 LTEGKQPSRALLRAQIGRPRGSFGDTLVSVTGAGSGIGRETAFAFAREGAEVVISDIDEA 358 Query 360 TVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLD 419 VK TAAEIA RGG+A+ YVLDVSDA+AVEAFA RVSAEHGVPDIVVNNAGIGQAG FLD Sbjct 359 AVKATAAEIATRGGVAHAYVLDVSDAQAVEAFAARVSAEHGVPDIVVNNAGIGQAGGFLD 418 Query 420 TPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 479 TPAEQFDRVL VNLGGVVNGCR+FG+R+VERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA Sbjct 419 TPAEQFDRVLDVNLGGVVNGCRSFGRRMVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 478 Query 480 ATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAP-GTDEEKIDGRRGQIDKMF 538 ATYMFSDCLRAELD AGVGLTTICPGVIDTNI+ TT F AP G E +DGRRGQ+ MF Sbjct 479 ATYMFSDCLRAELDTAGVGLTTICPGVIDTNIIKTTRFDAPAGKLAEAVDGRRGQLGTMF 538 Query 539 ALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 ALR YGPDKVA+AI+S+V+KKKPIRPVAPEAYALYG+SRV PQ LR+ AR+RVI Sbjct 539 ALRRYGPDKVANAILSSVRKKKPIRPVAPEAYALYGLSRVAPQGLRNAARMRVI 592 >gi|342857219|ref|ZP_08713875.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] gi|342134552|gb|EGT87718.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] Length=592 Score = 972 bits (2514), Expect = 0.0, Method: Compositional matrix adjust. Identities = 472/592 (80%), Positives = 525/592 (89%), Gaps = 3/592 (0%) Query 2 PATQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRY 61 P+ Q VDS DG RIAVY EGNP+GPTVVLVHGFPDSHVLWDGVVPLLAERFRI+RY Sbjct 3 PSPQVPQHFVDSADGARIAVYEEGNPEGPTVVLVHGFPDSHVLWDGVVPLLAERFRIIRY 62 Query 62 DNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGA 121 DNRGVG SSVPKP+SAY+M FADDF AV GELSPG PVHVLAHDWGSVGVW YL+RPGA Sbjct 63 DNRGVGLSSVPKPVSAYSMDRFADDFAAVTGELSPGRPVHVLAHDWGSVGVWHYLKRPGA 122 Query 122 SDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLL 181 +DRVA+FTSVSGP+QD LV+Y++ GLR PW+PRTFLRAISQ LRL+YM FS+PV+APL Sbjct 123 NDRVATFTSVSGPAQDQLVDYIFSGLRAPWKPRTFLRAISQALRLTYMIFFSIPVLAPLF 182 Query 182 LRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIV 241 LR+ +S A+RRN V +I V+QIHHSE LA DAAHSVKTYPANYFRSFS ++G + ++ Sbjct 183 LRLTMSVPALRRNAVDNISVEQIHHSEKLASDAAHSVKTYPANYFRSFSGRKQG--VAVI 240 Query 242 DVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLA 301 D PVQLIVN++D YVRPYGYD T R+VPRLWRRD+ AGHFSPMSHPQVMAAAVH+FAD A Sbjct 241 DAPVQLIVNTKDKYVRPYGYDHTPRFVPRLWRRDVAAGHFSPMSHPQVMAAAVHEFADHA 300 Query 302 DGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATV 361 +GKQPSRALLRAQVGRPRG FGDTLVSVTGAGSGIGRETA AFAREGAE+VISDIDEA V Sbjct 301 EGKQPSRALLRAQVGRPRGSFGDTLVSVTGAGSGIGRETAFAFAREGAELVISDIDEAAV 360 Query 362 KDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTP 421 K TAAEIA RGG+A+ YVLDVSDA+AVE+FAERVS EHGVPDIVVNNAGIG AG FLDTP Sbjct 361 KATAAEIATRGGVAHAYVLDVSDAQAVESFAERVSTEHGVPDIVVNNAGIGHAGGFLDTP 420 Query 422 AEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAAT 481 EQFDRVL VNLGGVVNGCR+F +R+VERGTGG+IVNVSSMAAYAPLQSL+AYCTSKAAT Sbjct 421 PEQFDRVLDVNLGGVVNGCRSFARRMVERGTGGYIVNVSSMAAYAPLQSLNAYCTSKAAT 480 Query 482 YMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAP-GTDEEKIDGRRGQIDKMFAL 540 YMFSDCLRAELDAAGVGLTTICPGVIDTNI+ TT F AP G + +DGRRGQ+ KMFAL Sbjct 481 YMFSDCLRAELDAAGVGLTTICPGVIDTNIINTTRFDAPAGKQSDDVDGRRGQLGKMFAL 540 Query 541 RSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 R YGPDKVA+AI+S+VKKKKPIRPVAPEAYALYG+SR+ PQ LR+ AR+RVI Sbjct 541 RHYGPDKVANAILSSVKKKKPIRPVAPEAYALYGLSRLAPQGLRNAARMRVI 592 >gi|118464693|ref|YP_881479.1| short chain dehydrogenase [Mycobacterium avium 104] gi|118165980|gb|ABK66877.1| short chain dehydrogenase [Mycobacterium avium 104] Length=592 Score = 955 bits (2469), Expect = 0.0, Method: Compositional matrix adjust. Identities = 469/594 (79%), Positives = 523/594 (89%), Gaps = 4/594 (0%) Query 1 MPATQQM-SRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIV 59 MPA Q V S DG RIAVY EGNP+GPTVVLVHGFPDSHVLWDGVVPLLAERFRI+ Sbjct 1 MPAPQHSPQHFVHSADGTRIAVYDEGNPEGPTVVLVHGFPDSHVLWDGVVPLLAERFRIL 60 Query 60 RYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRP 119 RYDNRGVG SS PKP+SAY M FADDF AVIGELSPG PVHVLAHDWGSVGVW YL+RP Sbjct 61 RYDNRGVGASSAPKPVSAYRMDRFADDFAAVIGELSPGGPVHVLAHDWGSVGVWHYLKRP 120 Query 120 GASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAP 179 GA+DRVA+FTSVSGPSQD LV+Y++ GLR PWRPR F RA+ Q LRLSYM L S+PV+AP Sbjct 121 GANDRVATFTSVSGPSQDQLVDYIFSGLRAPWRPRAFARALGQALRLSYMILLSIPVLAP 180 Query 180 LLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIP 239 L LR+ LS A+RRN V +IP++QIHHS+ LA DAA SVKTYPANYFRSF+ ++G + Sbjct 181 LALRLTLSIPALRRNAVDNIPIEQIHHSDRLAADAARSVKTYPANYFRSFAIRKQG--VA 238 Query 240 IVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD 299 ++DVPVQLIVN++D YVRPYGYD T R+VPRLWRRDI+AGHFSPMSHPQVMAAAVHDFAD Sbjct 239 VIDVPVQLIVNTEDRYVRPYGYDHTPRFVPRLWRRDIRAGHFSPMSHPQVMAAAVHDFAD 298 Query 300 LADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEA 359 +A+GK SRALLRAQVGRPR FGDTLVSVTGAGSGIGR TA AFAREGAE+++SDIDEA Sbjct 299 MAEGKPASRALLRAQVGRPRKAFGDTLVSVTGAGSGIGRATAFAFAREGAELIVSDIDEA 358 Query 360 TVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLD 419 VK TAAEIA RGG+A+ YVLDVSDA+AVE FAERVSA HGVPDIVVNNAGIGQAG FLD Sbjct 359 AVKATAAEIAGRGGVAHAYVLDVSDAQAVEEFAERVSAAHGVPDIVVNNAGIGQAGGFLD 418 Query 420 TPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 479 TPAE+FDRVLAVNLGGVVNGCR+F +R+V+RGTGGH+VNVSSMAAYAPLQSLSAYCTSKA Sbjct 419 TPAEEFDRVLAVNLGGVVNGCRSFARRMVQRGTGGHLVNVSSMAAYAPLQSLSAYCTSKA 478 Query 480 ATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAP-GTDEEKIDGRRGQIDKMF 538 AT+MFSDCLRAELDAAGVGLTTICPG+IDTNI+ TT F AP G E++D RRGQ+ KMF Sbjct 479 ATFMFSDCLRAELDAAGVGLTTICPGLIDTNIINTTRFDAPAGARAERVDDRRGQLGKMF 538 Query 539 ALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 ALR YGPDKVADAI+S+V+KKKPIRPVAPEAYALYG+SRV+PQ LR+ ARLRVI Sbjct 539 ALRHYGPDKVADAILSSVQKKKPIRPVAPEAYALYGLSRVMPQGLRNAARLRVI 592 >gi|254774947|ref|ZP_05216463.1| short chain dehydrogenase [Mycobacterium avium subsp. avium ATCC 25291] Length=581 Score = 952 bits (2461), Expect = 0.0, Method: Compositional matrix adjust. Identities = 464/581 (80%), Positives = 518/581 (90%), Gaps = 3/581 (0%) Query 13 SPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVP 72 S DG RIAVY EGNP+GPTVVLVHGFPDSHVLWDGVVPLLAERFRI+RYDNRGVG SS P Sbjct 3 SADGTRIAVYDEGNPEGPTVVLVHGFPDSHVLWDGVVPLLAERFRILRYDNRGVGASSAP 62 Query 73 KPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVS 132 KP+SAY M FADDF AVIGELSPG PVHVLAHDWGSVGVW YL+RPGA+DRVA+FTSVS Sbjct 63 KPVSAYRMDRFADDFAAVIGELSPGGPVHVLAHDWGSVGVWHYLKRPGANDRVATFTSVS 122 Query 133 GPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVR 192 GPSQD LV+Y++ GLR PWRPR F RA+ Q LRLSYM L S+PV+APL LR+ LS A+R Sbjct 123 GPSQDQLVDYIFSGLRAPWRPRAFARALGQALRLSYMILLSIPVLAPLALRLTLSIPALR 182 Query 193 RNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQ 252 RN V +IP++QIHHS+ LA DAA SVKTYPANYFRSF+ ++G + ++DVPVQLIVN++ Sbjct 183 RNAVDNIPIEQIHHSDRLAADAARSVKTYPANYFRSFAIRKQG--VAVIDVPVQLIVNTE 240 Query 253 DPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLR 312 D YVRPYGYD T R+VPRLWRRDI+AGHFSPMSHPQVMAAAVHDFAD+A+GK SRALLR Sbjct 241 DRYVRPYGYDHTPRFVPRLWRRDIRAGHFSPMSHPQVMAAAVHDFADMAEGKPASRALLR 300 Query 313 AQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARG 372 AQVGRPR FGDTLVSVTGAGSGIGR TA AFAREGAE+++SDIDEA VK TAAEIA RG Sbjct 301 AQVGRPRKAFGDTLVSVTGAGSGIGRATAFAFAREGAELIVSDIDEAAVKATAAEIAGRG 360 Query 373 GIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVN 432 G+A+ YVLDVSDA+AVE FAERVSA HGVPDIVVNNAGIGQAG FLDTPAE+FDRVLAVN Sbjct 361 GVAHAYVLDVSDAQAVEEFAERVSAAHGVPDIVVNNAGIGQAGGFLDTPAEEFDRVLAVN 420 Query 433 LGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAEL 492 LGGVVNGCR+F +R+V+RGTGGH+VNVSSMAAYAPLQSLSAYCTSKAAT+MFSDCLRAEL Sbjct 421 LGGVVNGCRSFARRMVQRGTGGHLVNVSSMAAYAPLQSLSAYCTSKAATFMFSDCLRAEL 480 Query 493 DAAGVGLTTICPGVIDTNIVATTGFHAP-GTDEEKIDGRRGQIDKMFALRSYGPDKVADA 551 DAAGVGLTTICPG+IDTNI+ TT F AP G E++D RRGQ+ KMFALR YGPDKVADA Sbjct 481 DAAGVGLTTICPGLIDTNIINTTRFDAPAGARAERVDDRRGQLGKMFALRHYGPDKVADA 540 Query 552 IVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 I+S+V+KKKPIRPVAPEAYALYG+SRV+PQ LR+ ARLRVI Sbjct 541 ILSSVQKKKPIRPVAPEAYALYGLSRVMPQGLRNAARLRVI 581 >gi|336461814|gb|EGO40670.1| short-chain dehydrogenase of unknown substrate specificity [Mycobacterium avium subsp. paratuberculosis S397] Length=592 Score = 942 bits (2435), Expect = 0.0, Method: Compositional matrix adjust. Identities = 468/594 (79%), Positives = 524/594 (89%), Gaps = 4/594 (0%) Query 1 MPATQQMSR-LVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIV 59 MPA Q + V S DG RIAVY EGNP+GPTVVLVHGFPDSHVLWDGVVPLLAERFRI+ Sbjct 1 MPAPQHSPQHFVHSADGTRIAVYDEGNPEGPTVVLVHGFPDSHVLWDGVVPLLAERFRIL 60 Query 60 RYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRP 119 RYDNRGVG SS PKP+SAY M FADDF AVIGELSPG PVHVLAHDWGSVGVW YL+RP Sbjct 61 RYDNRGVGASSAPKPVSAYRMDRFADDFAAVIGELSPGGPVHVLAHDWGSVGVWHYLKRP 120 Query 120 GASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAP 179 GA+DRVA+FTSVSGPSQD LV+Y++ GLR PWRPR F RA+ Q LRLSYM L S+PV+AP Sbjct 121 GANDRVATFTSVSGPSQDQLVDYIFSGLRAPWRPRAFARALGQALRLSYMILLSIPVLAP 180 Query 180 LLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIP 239 L+LR+ LS A+RRN V +IPV+QIHHS+ LA DAA +VKTYPANYFRSF+ ++G + Sbjct 181 LVLRLTLSIPALRRNAVDNIPVEQIHHSDRLAADAARAVKTYPANYFRSFAIRKQG--VA 238 Query 240 IVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD 299 ++DVPVQLIVN++D YVRPYGYD T R+VPRLWRRDI+AGHFSPMSHPQVMAAAVHDFAD Sbjct 239 VIDVPVQLIVNTEDRYVRPYGYDHTPRFVPRLWRRDIRAGHFSPMSHPQVMAAAVHDFAD 298 Query 300 LADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEA 359 +A+GK SRALLRAQVGRPR FGDTLVSVTGAGSGIGR TA AFAREGAE+++SDIDEA Sbjct 299 MAEGKPASRALLRAQVGRPRKAFGDTLVSVTGAGSGIGRATAFAFAREGAELIVSDIDEA 358 Query 360 TVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLD 419 VK TAAEIA RGG+A+ YVLDVSDA+AVE FAERVSA HGVPDIVVNNAGIGQAG FLD Sbjct 359 AVKATAAEIAGRGGVAHAYVLDVSDAQAVEEFAERVSAAHGVPDIVVNNAGIGQAGGFLD 418 Query 420 TPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 479 TPAE+FDRVLAVNLGGVVNGCR+F +R+V+RGTGGH+VNVSSMAAYAPLQSLSAYCTSKA Sbjct 419 TPAEEFDRVLAVNLGGVVNGCRSFARRMVQRGTGGHLVNVSSMAAYAPLQSLSAYCTSKA 478 Query 480 ATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAP-GTDEEKIDGRRGQIDKMF 538 AT+MFSDCLRAELD AGVGLTTICPG+IDTNI+ TT F AP G E++D RRGQ+ KMF Sbjct 479 ATFMFSDCLRAELDVAGVGLTTICPGLIDTNIINTTRFDAPAGARAERVDDRRGQLGKMF 538 Query 539 ALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 ALR YGPDKVADAI+S+V+KKKPIRPVAPEAYALYG+SRV+PQ LR+ ARLRVI Sbjct 539 ALRHYGPDKVADAILSSVQKKKPIRPVAPEAYALYGLSRVMPQGLRNAARLRVI 592 >gi|41408053|ref|NP_960889.1| short chain dehydrogenase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396408|gb|AAS04272.1| EphD [Mycobacterium avium subsp. paratuberculosis K-10] Length=592 Score = 940 bits (2429), Expect = 0.0, Method: Compositional matrix adjust. Identities = 468/594 (79%), Positives = 524/594 (89%), Gaps = 4/594 (0%) Query 1 MPATQQMSR-LVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIV 59 MPA Q + V S DG RIAVY EGNP+GPTVVLVHGFPDSHVLWDGVVPLLAERFRI+ Sbjct 1 MPAPQHSPQHFVHSADGTRIAVYDEGNPEGPTVVLVHGFPDSHVLWDGVVPLLAERFRIL 60 Query 60 RYDNRGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRP 119 RYDNRGVG SS PKP+SAY M FADDF AVIGELSPG PVHVLAHDWGSVGVW YL+RP Sbjct 61 RYDNRGVGASSAPKPVSAYRMDRFADDFAAVIGELSPGGPVHVLAHDWGSVGVWHYLKRP 120 Query 120 GASDRVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAP 179 GA+DRVA+FTSVSGPSQD LV+Y++ GLR PWRPR F RA+ Q LRLSYM L S+PV+AP Sbjct 121 GANDRVATFTSVSGPSQDQLVDYIFSGLRAPWRPRAFARALGQALRLSYMILLSIPVLAP 180 Query 180 LLLRVALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIP 239 L+LR+ LS A+RRN V +IPV+QIHHS+ LA DAA +VKTYPANYFRSF+ ++G + Sbjct 181 LVLRLTLSIPALRRNAVDNIPVEQIHHSDRLAADAARAVKTYPANYFRSFAIRKQG--VA 238 Query 240 IVDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD 299 ++DVPVQLIVN++D YVRPYGYD T R+VPRL RRDI+AGHFSPMSHPQVMAAAVHDFAD Sbjct 239 VIDVPVQLIVNTEDRYVRPYGYDHTPRFVPRLRRRDIRAGHFSPMSHPQVMAAAVHDFAD 298 Query 300 LADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEA 359 +A+GK SRALLRAQVGRPR FGDTLVSVTGAGSGIGR TA AFAREGAE+++SDIDEA Sbjct 299 MAEGKPASRALLRAQVGRPRKAFGDTLVSVTGAGSGIGRATAFAFAREGAELIVSDIDEA 358 Query 360 TVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLD 419 VK TAAEIA RGG+A+ YVLDVSDA+AVE FAERVSA HGVPDIVVNNAGIGQAG FLD Sbjct 359 AVKATAAEIAGRGGVAHAYVLDVSDAQAVEEFAERVSAAHGVPDIVVNNAGIGQAGGFLD 418 Query 420 TPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKA 479 TPAE+FDRVLAVNLGGVVNGCR+F +R+V+RGTGGH+VNVSSMAAYAPLQSLSAYCTSKA Sbjct 419 TPAEEFDRVLAVNLGGVVNGCRSFARRMVQRGTGGHLVNVSSMAAYAPLQSLSAYCTSKA 478 Query 480 ATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAP-GTDEEKIDGRRGQIDKMF 538 AT+MFSDCLRAELDAAGVGLTTICPG+IDTNI+ TT F AP G E++D RRGQ+ KMF Sbjct 479 ATFMFSDCLRAELDAAGVGLTTICPGLIDTNIINTTRFDAPAGARAERVDDRRGQLGKMF 538 Query 539 ALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 ALR YGPDKVADAI+S+V+KKKPIRPVAPEAYALYG+SRV+PQ LR+ ARLRVI Sbjct 539 ALRHYGPDKVADAILSSVQKKKPIRPVAPEAYALYGLSRVMPQGLRNAARLRVI 592 >gi|108800277|ref|YP_640474.1| short chain dehydrogenase [Mycobacterium sp. MCS] gi|119869405|ref|YP_939357.1| short chain dehydrogenase [Mycobacterium sp. KMS] gi|126435900|ref|YP_001071591.1| short chain dehydrogenase [Mycobacterium sp. JLS] gi|108770696|gb|ABG09418.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. MCS] gi|119695494|gb|ABL92567.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. KMS] gi|126235700|gb|ABN99100.1| short-chain dehydrogenase/reductase SDR [Mycobacterium sp. JLS] Length=588 Score = 738 bits (1906), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/585 (67%), Positives = 461/585 (79%), Gaps = 4/585 (0%) Query 9 RLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGR 68 R VDS DGVR+AVY EGNPDGPTV+LVHG+PDSHV+WD V LA+RF +VRYDNRGV Sbjct 7 RFVDSTDGVRVAVYEEGNPDGPTVILVHGWPDSHVVWDSVAAELADRFHVVRYDNRGVSP 66 Query 69 SSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASF 128 +S PK +AYT A +ADDF AV ++PG VHV+AHDWGS G+WEYL RP A+DRVAS+ Sbjct 67 TSAPKRAAAYTTARYADDFAAVADAVAPGRRVHVVAHDWGSTGMWEYLSRPEAADRVASY 126 Query 129 TSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSS 188 TS+SGPS DH+ YV GL+RP+R R RA++Q RLSYM L SVP+VAP+L+R ++ Sbjct 127 TSLSGPSVDHVYRYVLDGLKRPYRIRRLARALNQFARLSYMILLSVPLVAPVLVRAFIAE 186 Query 189 AAVRRNMVGD-IPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQL 247 + V + IP D++ HS+T DAA SVK Y ANYFRS + R R +VDVPVQL Sbjct 187 GLRKYQRVAEGIPADRLLHSDTYRADAARSVKVYRANYFRSLLTKRTPR---VVDVPVQL 243 Query 248 IVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPS 307 IVN+ D ++RPY YD+ A WVP LWRR+++AGH+SPMSHP V+A AV + + DG + Sbjct 244 IVNTGDAFIRPYVYDEIAPWVPTLWRRELRAGHWSPMSHPHVIARAVAELVEHVDGAPAA 303 Query 308 RALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAE 367 R L RA+VG PR YF DTLVSVTGAGSGIGRETALAFAREGAE+V+SDIDEA+ K+TAA Sbjct 304 RELRRARVGGPREYFSDTLVSVTGAGSGIGRETALAFAREGAELVVSDIDEASAKETAAA 363 Query 368 IAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDR 427 I A GG+A+ Y LDV+DA+AVE FA+ V A HG+PDIVVNNAG+GQAGRFLDTP +Q+D Sbjct 364 IEAAGGVAHAYRLDVADADAVERFADEVCAGHGIPDIVVNNAGVGQAGRFLDTPRDQWDH 423 Query 428 VLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDC 487 VL VNLGGVVNGCRAF +RLVERGTGGHIVNV+SMA+YAPLQSL+AYCTSKAA YMFSDC Sbjct 424 VLDVNLGGVVNGCRAFARRLVERGTGGHIVNVASMASYAPLQSLNAYCTSKAAVYMFSDC 483 Query 488 LRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDK 547 LRAELD AG+GLTTICP +DTNIV T HAP + GRRGQ+ KMFA+R YGPDK Sbjct 484 LRAELDEAGIGLTTICPSTVDTNIVRNTRIHAPADRTGDVAGRRGQLQKMFAMRRYGPDK 543 Query 548 VADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 A AIV+AVK K IRPV PEAY +YG+SRVLPQALRSTAR RV+ Sbjct 544 AAKAIVAAVKANKAIRPVMPEAYFVYGVSRVLPQALRSTARGRVL 588 >gi|118468842|ref|YP_888558.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] gi|118170129|gb|ABK71025.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] Length=578 Score = 687 bits (1773), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/586 (61%), Positives = 421/586 (72%), Gaps = 8/586 (1%) Query 7 MSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGV 66 M V S DG RIAVY +G+P+ PT+V+ HG+PDSHVLWDGVV L +R+RIVRYDNRG Sbjct 1 MYTFVTSQDGTRIAVYQQGDPERPTLVMAHGWPDSHVLWDGVVGELGDRYRIVRYDNRGA 60 Query 67 GRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVA 126 G S VPK SAYTM FADDF AVI +SP PVHVLAHDWGSVG+WEYL R G++ R+ Sbjct 61 GASDVPKATSAYTMERFADDFSAVIDAVSPDAPVHVLAHDWGSVGIWEYLSRQGSAARMV 120 Query 127 SFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVAL 186 SFTSVSGPS DH YV GL RP+RP F RA++ R SY FS+PV+AP L+R Sbjct 121 SFTSVSGPSTDHYGAYVRRGLARPYRPVQFARAVNLASRFSYWIPFSIPVLAPALMR--- 177 Query 187 SSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQ 246 A RR D P + SE L DAA+S+K Y AN RSF+ RR V VPVQ Sbjct 178 -RGAARRLQAIDTPGPKFQ-SENLDIDAANSLKIYRANAIRSFTHVRRDH---YVQVPVQ 232 Query 247 LIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQP 306 LI N +DP VR GY ++WVP LWRRD+ AGH++P SHP+ +A AV +F D +G P Sbjct 233 LICNRKDPVVRGEGYRDESKWVPLLWRRDLDAGHWAPFSHPRAIAQAVGEFVDHMEGAPP 292 Query 307 SRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAA 366 +RAL RA+V RPR F D LVSVTGA SGIGR TAL FAR GAEIV+SDIDEA K TA Sbjct 293 ARALRRAEVARPRKAFSDMLVSVTGAASGIGRATALEFARLGAEIVVSDIDEAGAKATAT 352 Query 367 EIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFD 426 I GG+A+ Y LDV+D +AV+ F + V A HGVPDIVVNNAGIG AG FLDTPA+Q++ Sbjct 353 AIDEAGGVAHAYGLDVADPDAVQRFVDDVCATHGVPDIVVNNAGIGHAGNFLDTPADQYE 412 Query 427 RVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSD 486 RVL VN GGVVN CRAFG+RLVE+GTGGHIVNV+SMAAY+P S++AY TSKAA +MFSD Sbjct 413 RVLEVNFGGVVNCCRAFGRRLVEQGTGGHIVNVASMAAYSPAGSMNAYATSKAAVFMFSD 472 Query 487 CLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPD 546 CLRAEL AG+G+TT+CPG+IDT IV TT F P +++ RR Q+ K F R YGP+ Sbjct 473 CLRAELAHAGIGVTTLCPGMIDTGIVDTTRFDVPAHKAGQVEARRAQVKKTFQARRYGPE 532 Query 547 KVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 KVA A+ SAV + + +RPV PEAY YG+SR+ P ALR AR +V+ Sbjct 533 KVAKAVTSAVSRNQALRPVTPEAYVAYGVSRLFPAALRRAARSQVL 578 >gi|145223524|ref|YP_001134202.1| short chain dehydrogenase [Mycobacterium gilvum PYR-GCK] gi|315443870|ref|YP_004076749.1| hypothetical protein Mspyr1_22690 [Mycobacterium sp. Spyr1] gi|145216010|gb|ABP45414.1| short-chain dehydrogenase/reductase SDR [Mycobacterium gilvum PYR-GCK] gi|315262173|gb|ADT98914.1| short-chain dehydrogenase of unknown substrate specificity [Mycobacterium sp. Spyr1] Length=543 Score = 563 bits (1451), Expect = 3e-158, Method: Compositional matrix adjust. Identities = 318/580 (55%), Positives = 383/580 (67%), Gaps = 46/580 (7%) Query 9 RLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGR 68 R V S DGVRIAVY EG DGPTVVLVHG D+H WD VV LLA RFRIVRYD RG GR Sbjct 5 RFVVSRDGVRIAVYEEGAADGPTVVLVHGHADTHEAWDAVVALLAARFRIVRYDTRGAGR 64 Query 69 SSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASF 128 S+ P+ S + + +ADD AV+ +S PVHVLAHD GS GVW YL RP + R+ASF Sbjct 65 SAAPQRTSGFRLERYADDLAAVLDAVSAEAPVHVLAHDRGSAGVWRYLARPESRGRLASF 124 Query 129 TSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSS 188 TSVSGP+ +H+ Y+ L RP P F + RL+ A +V Sbjct 125 TSVSGPAPEHVARYLRDTLARPQHPARFAGGLGHLARLAAAAPRAV-------------- 170 Query 189 AAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLI 248 + KT AN F S G VD+PVQLI Sbjct 171 ----------------------------TDKTLRANLFPVSS----GGDAHDVDIPVQLI 198 Query 249 VNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSR 308 V S DPY P+ ++ A RLWRRD+KAGH +P SHP ++A A+ D DG +R Sbjct 199 VGSADPYPDPHLFEDRAGRPARLWRRDVKAGHVTPTSHPGILARALTQLVDHLDGAPAAR 258 Query 309 ALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEI 368 LLRAQVGRPR FGDTLV+VTGA SGIGR TALAFA GA++VISD++ A + +TA + Sbjct 259 ELLRAQVGRPRKAFGDTLVAVTGAASGIGRATALAFAHHGADVVISDVNAAGLDETARLV 318 Query 369 AARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRV 428 + G AYPY +DV+DA AVEAFAE+V AEHGVPD+VVNNAG+G AG FLDTPAE+FDRV Sbjct 319 TSAGVHAYPYTVDVADAAAVEAFAEQVCAEHGVPDVVVNNAGVGHAGFFLDTPAEEFDRV 378 Query 429 LAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL 488 L +N GGVVNGCR+FG+RL +RG GGHIVNV+SMA+Y P+ ++AYCTSKAA +MFSDCL Sbjct 379 LDINFGGVVNGCRSFGKRLADRGVGGHIVNVASMASYTPVNVMNAYCTSKAAVFMFSDCL 438 Query 489 RAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKV 548 RAELD+ G+GLTTICPG I TNIV TT F ++ +D RG+ K F+ R YGP+KV Sbjct 439 RAELDSFGIGLTTICPGFISTNIVDTTRFSLAQGRDDDVDVLRGRAQKGFSARKYGPEKV 498 Query 549 ADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTAR 588 ADAIV AV+ K IRPVAPEA +YG++ LPQ LRSTAR Sbjct 499 ADAIVDAVRTNKAIRPVAPEARFVYGVAHALPQVLRSTAR 538 >gi|169631098|ref|YP_001704747.1| short chain dehydrogenase [Mycobacterium abscessus ATCC 19977] gi|169243065|emb|CAM64093.1| Probable oxidoreductase EphD [Mycobacterium abscessus] Length=606 Score = 530 bits (1366), Expect = 3e-148, Method: Compositional matrix adjust. Identities = 276/572 (49%), Positives = 364/572 (64%), Gaps = 13/572 (2%) Query 17 VRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPIS 76 + +A + +GNP+G T++LVHG+PDSH LWDGV PLL +RFR+V DNRG G+SS PK Sbjct 25 IDVAYFMQGNPEGETILLVHGWPDSHHLWDGVAPLLRDRFRLVAIDNRGAGKSSNPKSFR 84 Query 77 AYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQ 136 + + A D+ AV +SP +PVHVL HDWGSV +WE + P R +SFTSVSGPS Sbjct 85 DFRLTEMASDYVAVADAVSPDKPVHVLGHDWGSVAMWEAICDPELEHRFSSFTSVSGPSA 144 Query 137 DHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRR--N 194 H+ +V P P+ A+ Q L YM PV+ +LL++ ++ R + Sbjct 145 HHMSKWVRSRFGNP-TPKNLALALGQIGSLLYMFGSMTPVIPNVLLKLTMNERRWRTGLS 203 Query 195 MVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSF--SSSRRGRAIPIVDVPVQLIVNSQ 252 + PV+ IH T D +++ Y AN + R R VPVQ+IV ++ Sbjct 204 LAEGAPVEDIHLGSTFMSDITRTLRVYRANALPAMLHPQDRHTR------VPVQVIVGTR 257 Query 253 DPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLR 312 DP VR YD +W + WRR + GH+ P SHPQV+AAA + D G QP R L R Sbjct 258 DPAVRQSNYDDELKWNQQTWRRVLDGGHWLPFSHPQVLAAATAELIDAVSGNQPGRGLRR 317 Query 313 AQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARG 372 A++G+ R F D LV +TG GSGIGRETAL FAR+GAE+V+SD++ +T + I G Sbjct 318 AEMGKSRRPFEDQLVVITGGGSGIGRETALEFARQGAEVVLSDVNLDGANETVSLIEQSG 377 Query 373 GIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVN 432 G+A+ Y L+V+D EAV A AE V HGVPD++VNNAG+G AG FLDTP+E+F RV+ N Sbjct 378 GVAHAYRLNVADEEAVNAHAEEVVKRHGVPDVLVNNAGVGAAGGFLDTPSEEFRRVIETN 437 Query 433 LGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAEL 492 L GVVNG RAFG ++ ERG GGHIVN+SSMAAY+P ++ +AY TSK+A +MFSDCLRA+L Sbjct 438 LFGVVNGSRAFGAKMAERGLGGHIVNLSSMAAYSPQKAFTAYSTSKSAVFMFSDCLRADL 497 Query 493 DAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVADAI 552 A +G+TTICPGV+ TNIVATT DEE + G D+ +A+R YGP+KVA I Sbjct 498 AAHNIGVTTICPGVVHTNIVATTKISGVSADEEARMQQAG--DRAYAMRRYGPEKVARQI 555 Query 553 VSAVKKKKPIRPVAPEAYALYGISRVLPQALR 584 V AV+K K + PV PEA Y +R+ P R Sbjct 556 VGAVRKNKQVVPVTPEARLQYLNNRLAPGLTR 587 >gi|317507424|ref|ZP_07965157.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974] gi|316254271|gb|EFV13608.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974] Length=612 Score = 526 bits (1355), Expect = 4e-147, Method: Compositional matrix adjust. Identities = 270/570 (48%), Positives = 362/570 (64%), Gaps = 9/570 (1%) Query 17 VRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPIS 76 + + + +GNP+G T++LVHG+PDSH LWD V PLL +RFR+V DNRGVG+++ PK Sbjct 29 IDVTYFVQGNPEGETILLVHGWPDSHHLWDNVTPLLRDRFRLVAVDNRGVGKTTNPKSFR 88 Query 77 AYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQ 136 + + A D+ AV +SP +PVHVL HDWGSV WE + P R ASFTSVSGP Sbjct 89 DFRLTAMASDYVAVANAVSPAKPVHVLGHDWGSVAAWEAICDPELEHRFASFTSVSGPCL 148 Query 137 DHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNM- 195 H+ +V RP P+ A+ Q + Y P V LL++ +++ R + Sbjct 149 SHMSKWVRSRFSRP-TPKNVALALGQAGSVLYTLFSMTPGVPNALLKLTMTAERWRNGLS 207 Query 196 VGD-IPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQDP 254 +G+ PV++IH S T +D +++ Y AN F + + +VPVQ+IV DP Sbjct 208 LGEGAPVERIHLSPTFKQDITRTLRVYRANVFPALLHPQE----RYTNVPVQVIVGKNDP 263 Query 255 YVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLRAQ 314 VR YD W R WRR + GH+ P SHP+ +AAA + D G +P+RAL RA+ Sbjct 264 AVRQSCYDDEPLWNKRTWRRVLNGGHWLPFSHPEALAAATVELIDAVGGGEPARALRRAE 323 Query 315 VGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGI 374 +G+ R F D LV +TG GSGIGRETA FAR GAE+V+SDI+ + K+T I GG+ Sbjct 324 MGKDRKPFEDQLVVITGGGSGIGRETAREFARLGAEVVLSDINLVSAKETVVMIEEEGGV 383 Query 375 AYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLG 434 A+ Y L+V+D EA+ A AE V A HGVPD++VNNAG+G AG FL TP E+F R++ +NL Sbjct 384 AHAYQLNVADEEAINAHAEEVHANHGVPDVLVNNAGVGAAGDFLQTPTEEFKRIIDINLY 443 Query 435 GVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDA 494 GVVNG RAFG ++ ERG GGHIVN+SSMAAY+P + SAY TSK+A +MFSDCLRA+L A Sbjct 444 GVVNGSRAFGAKMAERGLGGHIVNLSSMAAYSPQKQFSAYSTSKSAVFMFSDCLRADLAA 503 Query 495 AGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIVS 554 +G+TTICPGV+ TNI+AT+ +EE+ G DK +A+R YGP+KVA IV Sbjct 504 HNIGVTTICPGVVHTNIIATSKISGVSAEEERRMQEVG--DKAYAMRRYGPEKVARQIVR 561 Query 555 AVKKKKPIRPVAPEAYALYGISRVLPQALR 584 +V+K K + PV PEAY Y R+ P R Sbjct 562 SVQKNKQVVPVTPEAYVQYLNYRMAPGLTR 591 >gi|343928526|ref|ZP_08767973.1| putative peptidase S33 family protein [Gordonia alkanivorans NBRC 16433] gi|343761537|dbj|GAA14899.1| putative peptidase S33 family protein [Gordonia alkanivorans NBRC 16433] Length=600 Score = 513 bits (1322), Expect = 3e-143, Method: Compositional matrix adjust. Identities = 281/585 (49%), Positives = 361/585 (62%), Gaps = 8/585 (1%) Query 11 VDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSS 70 V +PDGVRIAVY EGNPDG TV+L+HG+PDSH LWD V PLL +R+R++R DNRG GRSS Sbjct 19 VTTPDGVRIAVYEEGNPDGETVLLLHGWPDSHRLWDSVAPLLRDRYRLIRVDNRGHGRSS 78 Query 71 VPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTS 130 P A + ADD+ AVI ++ +PVH++AHDWGSV WE + RP RVASFTS Sbjct 79 SPSGRQAISTRRIADDYAAVIAHVA-DKPVHIIAHDWGSVSTWELITRPPEQARVASFTS 137 Query 131 VSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAA 190 +SGPS H + L RP P ++ +Y + SVPV++ LLLR +S+ Sbjct 138 ISGPSMGHFAAWARRRLLRP-SPANVGHVVAALASFAYSIVLSVPVLSTLLLRYGVSAGR 196 Query 191 VRRNMVG--DIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLI 248 RR I ++IH ET D + Y + ++ R +P VPVQ++ Sbjct 197 WRRQQAAAEGIAPERIHLGETFEHDVVDGARIYRSTLTSRHTNPLTARPLP-TRVPVQVL 255 Query 249 VNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSR 308 + +DP +R Y RW LW R + GH+ P SHP+++A A + + R Sbjct 256 IGKRDPAIRYRSYADVPRWTGDLWLRLVHGGHWLPFSHPELVAQAAEELIESVRTGTEPR 315 Query 309 ALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEI 368 +L R +VG R F D LV VTGAGSGIGR TA AFA GAE+V+SDID A +TA I Sbjct 316 SLRRWRVGTDRRPFADQLVVVTGAGSGIGRATAHAFAGAGAEVVVSDIDPAASAETAELI 375 Query 369 AARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRV 428 GG+AY Y LDVSD +V+ A V AEHGVPD++VNNAGIG AG FL TPA FDRV Sbjct 376 GRAGGVAYAYRLDVSDPASVDEHAREVIAEHGVPDVLVNNAGIGHAGAFLQTPAADFDRV 435 Query 429 LAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL 488 L VNL GV+ CRAF + ERG GG IVN++SMAAY+P + SAY TSK+A +MFSDCL Sbjct 436 LQVNLQGVIGMCRAFAGAMSERGLGGQIVNLASMAAYSPQREFSAYSTSKSAVFMFSDCL 495 Query 489 RAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKV 548 RAEL +GVG+TT+CPGV+ TNI ATT F G +E+ + D ++ R Y PDKV Sbjct 496 RAELARSGVGVTTVCPGVVHTNITATTRF--SGVSDEEEHRLQQHFDALYRRRGYTPDKV 553 Query 549 ADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALR-STARLRVI 592 A+ I+ AV + I PV PEA Y SR P+ R + AR+ ++ Sbjct 554 AERILRAVLAGETIVPVTPEAVVQYHFSRFAPKLTRLAAARMSLL 598 >gi|317505975|ref|ZP_07963807.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974] gi|316255751|gb|EFV14989.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974] Length=601 Score = 512 bits (1318), Expect = 7e-143, Method: Compositional matrix adjust. Identities = 283/587 (49%), Positives = 370/587 (64%), Gaps = 24/587 (4%) Query 17 VRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPIS 76 V +AV+ G+P PTVVL HG+PD+H +W+ VV LL +RF +V YD+RG G+S+ PK Sbjct 28 VDLAVFERGDPKNPTVVLTHGWPDTHHMWEQVVSLLEDRFHLVSYDSRGHGQSTSPKSFR 87 Query 77 AYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQ 136 + M ADD AVI +SP EPVH++AHDWGS WE + + A R+ASFTS+SGPS Sbjct 88 EWRMVDLADDIFAVIDAVSPDEPVHLVAHDWGSCASWEAVVQDRAKGRIASFTSISGPSL 147 Query 137 DHL---VNYVYGGL---RRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAA 190 D+L + V GL R PW SQT L Y F + + L L A Sbjct 148 DYLGTNLREVLAGLQLRRLPW-------VASQTASLLYQIFFHMTPLPQALFAAVLGKPA 200 Query 191 VRRNMVGDI---PVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQL 247 R + I P +Q++ + T +D A+ ++ Y AN ++ S R +VPVQL Sbjct 201 NWRRFLRTIEGTPAEQVNLAPTFGKDMANGLRVYWANSSQAAFGSPNPRP---TEVPVQL 257 Query 248 IVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPS 307 IVN D +R YD RW +LWR D+ GH+ S PQ +A V DF D DGK PS Sbjct 258 IVNRNDVAIRAETYDDYPRWASKLWRHDLSTGHWVAYSRPQAIATLVRDFVDGLDGK-PS 316 Query 308 RALLRAQV--GRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTA 365 R R +V G P+G F LVSVTGAGSGIGRETALAFAREGAE+V+SD++ AT ++TA Sbjct 317 RVFARGEVAKGAPKGDFAGKLVSVTGAGSGIGRETALAFAREGAELVLSDVNLATAQETA 376 Query 366 AEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQF 425 A I G +A+ Y LDVSD +A AF +RV AEHGVPD+VVNNAGIG G +D Q Sbjct 377 ALIEKVGSVAHAYQLDVSDLDAHAAFVDRVVAEHGVPDVVVNNAGIGFGGLIVDATEAQI 436 Query 426 DRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFS 485 D++L +NL GV++G + FG+ + RG GGHIVN+SSMAAY+P + + Y TSKAA +MFS Sbjct 437 DKLLGINLRGVISGSKLFGKHMALRGLGGHIVNLSSMAAYSPQKGIGLYATSKAAVFMFS 496 Query 486 DCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGP 545 D LRAEL AAG+G++TICPG++DTNI+ TT A ++EE+++ R G++DK++ R Y P Sbjct 497 DVLRAELHAAGIGVSTICPGIVDTNIIRTTQI-AGASEEERLE-RVGRLDKLYQARRYTP 554 Query 546 DKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 DKVA+ IV AVKK K + PV PE+ Y R P R ARL + Sbjct 555 DKVAEQIVRAVKKNKSVVPVTPESRLGYLQYRFAPWLSRLIARLDIF 601 >gi|296394715|ref|YP_003659599.1| short-chain dehydrogenase/reductase SDR [Segniliparus rotundus DSM 44985] gi|296181862|gb|ADG98768.1| short-chain dehydrogenase/reductase SDR [Segniliparus rotundus DSM 44985] Length=606 Score = 484 bits (1245), Expect = 3e-134, Method: Compositional matrix adjust. Identities = 271/596 (46%), Positives = 357/596 (60%), Gaps = 25/596 (4%) Query 8 SRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVG 67 SR S V +AVY G+P PTV+ HG+PD+H LW+ V LL +RF +V YD+RG G Sbjct 25 SRSAGSASAVTLAVYERGDPKNPTVLFAHGWPDTHCLWNQVAGLLEDRFHVVAYDSRGHG 84 Query 68 RSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVAS 127 +S+ P+ + M ADD AV +SP PVH++AHDWGSV WE + + A DR+AS Sbjct 85 QSTSPRSYRQWRMTDLADDIFAVAEAVSPDAPVHLVAHDWGSVAGWEAVVQDRAKDRLAS 144 Query 128 FTSVSGPSQDHLVNYVYGGL------RRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLL 181 FTS+SGPS D+L + L R PW A Q L Y F + + L Sbjct 145 FTSISGPSTDYLAVNIRETLGRLRVGRLPW-------AFGQIGSLLYQIFFHMSPLPQAL 197 Query 182 LRVALSSAAVRRNMVGDI---PVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAI 238 V+L AV R + I P QI + T +D A+ ++ Y AN + + G+ Sbjct 198 FAVSLGKPAVWRRFLRAIEGTPAKQIELAPTFRKDIANGLRVYWANS----APTAFGKPD 253 Query 239 PI-VDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDF 297 P DVP QLIVN D +RP YD+ +RWV RLWR D+ GH++ + PQ +A V DF Sbjct 254 PRPTDVPTQLIVNRNDVAIRPGTYDEYSRWVSRLWRHDLSTGHWAAYARPQAIATLVRDF 313 Query 298 ADLADGKQPSRALLRAQVG-RPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDI 356 D DGK PSR RA VG R +G F LV++TGAGSGIGRETALAFAREGAE+V+SD+ Sbjct 314 VDGLDGK-PSRVFERAAVGARGKGEFSGKLVAITGAGSGIGRETALAFAREGAELVLSDV 372 Query 357 DEATVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGR 416 ++ +VK+T + GG+A+PY LDVSD +A E F V A HGVPDIVVNNAGI G+ Sbjct 373 NDVSVKETVGLVEETGGVAHPYRLDVSDHQAYEQFVAEVVAAHGVPDIVVNNAGISIGGQ 432 Query 417 FLDTPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCT 476 LD +Q +R++ +N+ GV+ G R FG+ +VERG GGHIVN+SS+AA+ P + + Y Sbjct 433 ILDFTEDQVERIVGINVRGVITGSRLFGKHMVERGLGGHIVNLSSLAAFGPARGIGVYAA 492 Query 477 SKAATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDK 536 +K+A MFS+CLRAEL AGVG++ I PG++DTNIV T G E +IDK Sbjct 493 TKSAVAMFSECLRAELHGAGVGVSAILPGIVDTNIVRNT--QIAGLSEHDRLAHVARIDK 550 Query 537 MFALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRVI 592 + R + PDKVA I+ AV+K K + PV E+ Y R P R ARL + Sbjct 551 FYQRRGFTPDKVAKRILWAVRKNKAVVPVTIESQLGYRQYRFAPWLSRLIARLELF 606 >gi|343927405|ref|ZP_08766878.1| putative peptidase S33 family protein [Gordonia alkanivorans NBRC 16433] gi|343762742|dbj|GAA13804.1| putative peptidase S33 family protein [Gordonia alkanivorans NBRC 16433] Length=592 Score = 438 bits (1126), Expect = 1e-120, Method: Compositional matrix adjust. Identities = 251/578 (44%), Positives = 338/578 (59%), Gaps = 11/578 (1%) Query 17 VRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPIS 76 V +A + G+P PTV+LVHG+PD+H LW + P LAE++ +V YD RG G S P+ + Sbjct 21 VTLATFELGDPGNPTVLLVHGWPDTHHLWTHIAPRLAEKYHVVAYDCRGFGESDRPRKVG 80 Query 77 AYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQ 136 AY +A ADD AV +SP PVHV+ HDWGSV WE + RP A R+ASF SVSGP+ Sbjct 81 AYRLAELADDLFAVAEAVSPDAPVHVVGHDWGSVQAWEAVSRPRAHTRIASFVSVSGPNL 140 Query 137 DHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRR--N 194 DHL +++ GL RP P +Q+L +Y LF +PV+ LL + A +R + Sbjct 141 DHLGHFLRNGLTRP-TPHRVRTIATQSLSSAYTGLFQLPVLPNALLTALGNPRAWKRFLH 199 Query 195 MVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQDP 254 V P + + + TL RD + Y AN + R P VPV +VN +D Sbjct 200 TVEGTPPENVVVAGTLRRDMITGLALYRANIRQKL---LRPEPRPTT-VPVLQVVNERDI 255 Query 255 YVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLRAQ 314 +RP Y+ T + +LWRRD GH+ P ++P + V DF G + R++ Sbjct 256 ALRPAIYENTPTFAAKLWRRDTPTGHWLPYTNPDYLTETVLDFLAAQTGGDSPPTVERSR 315 Query 315 V-GRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGG 373 V G P+ G LV +TGAGSGIGRETAL A G E+V++D + T +T G Sbjct 316 VFGEPKPLAGK-LVVITGAGSGIGRETALLLAERGCELVLADRNLDTAAETEQACKVAGA 374 Query 374 IAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNL 433 +A+ Y+LDVSD +A +FA V +HGVPD+V+NNAGIG AG L EQ DR+L VNL Sbjct 375 VAHAYLLDVSDTDAFVSFAAAVREQHGVPDVVLNNAGIGLAGGALAATDEQVDRLLDVNL 434 Query 434 GGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELD 493 GV+ G R FG+++VERG GGHIVNVSS AA+ P +SL Y SKA +FS+ LRAEL Sbjct 435 RGVITGSREFGRQMVERGVGGHIVNVSSAAAFTPSRSLGLYSASKAGVLLFSESLRAELA 494 Query 494 AAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIV 553 +G++ ICPG++DTNIVA+T G D +R ++D+ + R + PD+VA IV Sbjct 495 EHRIGVSAICPGIVDTNIVASTPI--AGLDSASEQSQRDRLDRFYQRRGFTPDRVATEIV 552 Query 554 SAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRV 591 SA++ K + PV PEA Y I R P R AR V Sbjct 553 SAIEHNKAVVPVTPEAKVGYRIYRFAPWLSRIGARQNV 590 >gi|254428270|ref|ZP_05041977.1| oxidoreductase, short chain dehydrogenase/reductase family [Alcanivorax sp. DG881] gi|196194439|gb|EDX89398.1| oxidoreductase, short chain dehydrogenase/reductase family [Alcanivorax sp. DG881] Length=581 Score = 436 bits (1122), Expect = 5e-120, Method: Compositional matrix adjust. Identities = 246/586 (42%), Positives = 344/586 (59%), Gaps = 27/586 (4%) Query 13 SPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVP 72 S DGV +AV + PTVVLVHG+PD++ +W+ V L+ F++V YD RG G SS+P Sbjct 10 SRDGVDLAVRTWSSDKSPTVVLVHGYPDANHVWEKVAERLSRDFKVVAYDVRGAGNSSIP 69 Query 73 KPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVS 132 K +AY + DD AV+ + P E VH++ HDWGS+ WE + PGA R+AS+T++S Sbjct 70 KGRAAYKLRQLRDDLHAVMDAVCPNEKVHLVGHDWGSIQTWESVTDPGAEQRIASYTTLS 129 Query 133 GPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSA--- 189 GP DH+ ++ LR + T L ++ + Y+ F +PV+AP L +V L+ A Sbjct 130 GPCLDHVGQWMKARLREQ-KIGTVLNQLAHSW---YIGAFQLPVLAPTLWKVGLAKAWPQ 185 Query 190 AVRRNMVGDIPVDQIHHSETLA---RDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQ 246 +RR+ + HSET A +D H ++ Y AN S R VPVQ Sbjct 186 LLRRS--------ENLHSETSATQQQDGIHGIELYRANMRPSLLKPRE----RYTKVPVQ 233 Query 247 LIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPM-SHPQVMAAAVHDFADLADGKQ 305 LIV +D YVRP + W RLWRR++ GH+ P+ HP V A + +F DG Sbjct 234 LIVAREDNYVRPAMLEDLHLWTDRLWRRELDCGHWGPLLQHPDVTARWIREFIQHIDGAP 293 Query 306 PSRALLRAQVG--RPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKD 363 S L R++V P+G V VTGAGSGIGRETALAFAR GA ++ +DI+ Sbjct 294 ASGPLQRSEVTGTHPKGPDSGKRVVVTGAGSGIGRETALAFARRGALVLCTDINAEAAAS 353 Query 364 TAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAE 423 TA+ I GG A DVS+ ++EA A V E G PDI++NNAGIG +G LDT + Sbjct 354 TASIIIREGGDALSRKCDVSNTRSMEALANYVEKELGAPDILINNAGIGLSGSLLDTSVK 413 Query 424 QFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYM 483 + +VL VNL GV++GCR F +++V+ G GHIVNV+S AA+ P + L AY TSK+A M Sbjct 414 DWQQVLGVNLWGVIHGCRLFARQMVDNGKAGHIVNVASAAAFLPSRMLPAYATSKSAVLM 473 Query 484 FSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSY 543 FS+CLRAE+ +G++ ICPG+IDT I +T F G +E+ RR K++ R+Y Sbjct 474 FSECLRAEMAEHNIGVSAICPGIIDTPITRSTRF--VGVADEEQSRRREDAAKLYQRRAY 531 Query 544 GPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 PD+VA AIV AV+ + + PV+PEA + + R P R+ A++ Sbjct 532 TPDRVAQAIVEAVQNNRAVVPVSPEARGMQWLGRFTPSLARNLAQV 577 >gi|311899724|dbj|BAJ32132.1| putative peptidase S33 family protein [Kitasatospora setae KM-6054] Length=583 Score = 436 bits (1120), Expect = 7e-120, Method: Compositional matrix adjust. Identities = 259/584 (45%), Positives = 350/584 (60%), Gaps = 23/584 (3%) Query 9 RLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGR 68 R VDS G+ +AVY +G+P PTV+LVHG+PD H +WD V LA +VRYD RG G Sbjct 17 RTVDS-GGLPLAVYEQGDPADPTVILVHGYPDDHSVWDDVAADLAADHHVVRYDTRGSGA 75 Query 69 SSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASF 128 S VP + Y + D AV +SP PVHV+AHDWGSV WE + PGA R+AS+ Sbjct 76 SGVPAVRADYRLELLGQDLYAVADAVSPDRPVHVVAHDWGSVQAWEAVTAPGAYRRIASY 135 Query 129 TSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSS 188 T++SGP DH+ +++ LRRP PR + + Q Y+ALF +PV+AP ++ L+ Sbjct 136 TTMSGPCLDHMGHWIRHRLRRP-TPRHLSQLLRQGAHSWYIALFQLPVLAPAAWKLGLAR 194 Query 189 AAVR--RNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQ 246 R R++ P H TLA+DA H ++ Y AN + R +VPVQ Sbjct 195 LWPRVLRDLEAVRPRPG-HPQATLAKDAVHGIELYRANMRPRVRAPRERH----TEVPVQ 249 Query 247 LIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPM-SHPQVMAAAVHDFADLADGKQ 305 LI +D YV + + RW PRL RR + A H+S + +AA V +F G Sbjct 250 LITLQRDHYVADFLSEGLERWAPRLTRRTLNATHWSALLEKGPTVAAMVREFTARDHG-- 307 Query 306 PSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTA 365 A P G LV VTG GSGIGR TALAFA GA +V+ D D TA Sbjct 308 -------APRQEPSGT--GELVVVTGGGSGIGRATALAFADAGARVVVCDRDLPAALRTA 358 Query 366 AEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQF 425 G A Y +DVSD AV+AFA++V+ +HGVPD+VVNNAGIG +G FL T +++ Sbjct 359 ELCELSGVKAAAYRVDVSDGAAVDAFAQQVATDHGVPDVVVNNAGIGHSGTFLQTTEDEW 418 Query 426 DRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFS 485 RVL VNL GV++GCRAFGQ +V+RGTGGH+VN++S AAY P + L+AY TSK+A +M S Sbjct 419 RRVLDVNLWGVIHGCRAFGQLMVDRGTGGHLVNLASAAAYLPAKRLAAYATSKSAVFMLS 478 Query 486 DCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGP 545 DCLRAEL +G++TICPG++ TNI TT F G D++ + ++ ++ K++A R + P Sbjct 479 DCLRAELAPHRIGVSTICPGIVHTNITRTTTF--SGLDQDALAAKQAKVSKLYARRGFPP 536 Query 546 DKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 +KVA IV AV+ +KP+ PV EA A ++R+ P L AR+ Sbjct 537 EKVAAEIVRAVRTRKPVVPVTVEAKAARLLARLSPGLLHKAARI 580 >gi|302530522|ref|ZP_07282864.1| short-chain dehydrogenase/reductase SDR [Streptomyces sp. AA4] gi|302439417|gb|EFL11233.1| short-chain dehydrogenase/reductase SDR [Streptomyces sp. AA4] Length=573 Score = 433 bits (1113), Expect = 5e-119, Method: Compositional matrix adjust. Identities = 256/585 (44%), Positives = 349/585 (60%), Gaps = 19/585 (3%) Query 9 RLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGR 68 + V + DGVR++V GNPDGPTVVLVHG+PD+ +WDGV L +V YD RG G Sbjct 4 KQVTASDGVRLSVRVSGNPDGPTVVLVHGYPDNSSMWDGVAEELRREHCVVVYDVRGAGE 63 Query 69 SSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASF 128 S P+ AY + ADD AV+ E+ P VH++AHDWGS+ W + R+AS+ Sbjct 64 SDKPRERRAYRLDQLADDLAAVVDEVQPFGKVHLVAHDWGSIQAWHAVTGDRLRGRLASY 123 Query 129 TSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSS 188 TS+SGPS DH + L RP PR A+ Q L Y+ F VP++ LL R + Sbjct 124 TSLSGPSLDHAGAWFRDQLTRP-TPRRIGHALRQFLHSYYIVAFQVPLIPELLWRTGIMR 182 Query 189 AAVRRNMVGDIPVDQIHHSETLAR--DAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQ 246 +R+ + +ET + D H +K Y AN S R A ++PVQ Sbjct 183 TLIRK----------LEPAETSPKTIDGVHGLKLYRANMGPRLSRPRPRPA----EIPVQ 228 Query 247 LIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQP 306 ++ + D YV + RWVP L R + H+ + P+V+AAA + + + Sbjct 229 VLAPTGDSYVTAPLQTEVERWVPDLHVRRVIGSHWITRTKPEVVAAAAAELIASVETGEE 288 Query 307 SRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAA 366 +RAL RA+VG G F LV VTGAGSGIGRETALAFA EGA++V+SDI+ + +TA Sbjct 289 TRALRRARVGGASGRFAHHLVVVTGAGSGIGRETALAFAAEGADVVVSDINGDSAAETAK 348 Query 367 EIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFD 426 + RG A Y +D SD EAV FAE+V E GVPDIVVNNAGIG +G FLDT E ++ Sbjct 349 LVRERGVDAGEYTVDSSDGEAVARFAEQVRDEFGVPDIVVNNAGIGMSGPFLDTTIEDWE 408 Query 427 RVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSD 486 +V+ VNL GV++GCRAF + ER GGH+VN++S AAY P + L+AY T+KAA S+ Sbjct 409 KVVDVNLWGVIHGCRAFAPMMKERAEGGHLVNLASAAAYLPSKILTAYGTTKAAVLALSN 468 Query 487 CLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPD 546 LRAEL A G+G+T +CPG+++TNI TT F G DE + R+ + K++A R++GP+ Sbjct 469 GLRAELAADGIGVTAVCPGLVNTNITKTTTF--VGVDEVEEKRRQKESSKLYARRNFGPE 526 Query 547 KVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLRV 591 +VA I+ AV+K I+P PEA +SR+ P LR+ A+L V Sbjct 527 RVARDILRAVEKNVAIQPSTPEAKVALVLSRLTPGLLRAAAKLDV 571 >gi|134100092|ref|YP_001105753.1| short chain dehydrogenase [Saccharopolyspora erythraea NRRL 2338] gi|133912715|emb|CAM02828.1| short-chain dehydrogenase/reductase SDR [Saccharopolyspora erythraea NRRL 2338] Length=579 Score = 431 bits (1108), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 247/585 (43%), Positives = 343/585 (59%), Gaps = 18/585 (3%) Query 9 RLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGR 68 R+V + DG+ +AV+ G+PD PTVV VHG+PD H +WDGVV +LAE + +V YD RG G Sbjct 4 RVVTTGDGLSLAVWEHGDPDRPTVVAVHGYPDDHSVWDGVVRVLAEHYHVVTYDVRGAGE 63 Query 69 SSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASF 128 S P+ +AY + D AV+ +SP P H+LAHDWGS+ W+ + R+ASF Sbjct 64 SDKPRERAAYRLDRLVGDLAAVLDAVSPDRPAHLLAHDWGSIQAWQAVTEEQLRARIASF 123 Query 129 TSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSS 188 TS+SGP DH ++ G RRP PR + ++Q Y+ F +PV+ L A S Sbjct 124 TSISGPCLDHAGAWMRGQWRRP-TPRNLRQLLTQLAFSGYIGFFQLPVLPEL----AWYS 178 Query 189 AAVRRNMVGDIPVDQIHHSETLAR----DAAHSVKTYPANYFRSFSSSRRGRAIPIVDVP 244 A+ R + +D + T R D ++ Y AN S+ R R VP Sbjct 179 GAMSRLLSTVEKMDPVADG-TPPRPRIADGVRGLELYRANMMPRLSAPRVRR----TSVP 233 Query 245 VQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGK 304 VQ++ + DP+V ARWVP + R + GH+ P + P+++A + + + Sbjct 234 VQVLAPTGDPFVSTPLQAAAARWVPEMRLRRLPGGHWLPRTRPELIARCAAELVENVESG 293 Query 305 QPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDT 364 R+L +A+VG G F D LV +TGAGSGIGR TAL A GAEIV +D+DE T Sbjct 294 AEPRSLRQARVGS--GRFADRLVVITGAGSGIGRATALELAERGAEIVAADVDEKAAART 351 Query 365 AAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQ 424 A A G A PY +DVSD EA++ FAE V GVPDIVVNNAGIG AG F DT E Sbjct 352 AELAALLGPGATPYQVDVSDGEAMQRFAEDVRTRLGVPDIVVNNAGIGMAGAFADTTTED 411 Query 425 FDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMF 484 ++RV+ VNL GV++GCR F +++ ERG GG IVN++S AAY P ++L AY T+KAA Sbjct 412 WERVIDVNLWGVIHGCRLFARQMTERGEGGRIVNIASAAAYLPSRTLPAYSTTKAAVLAL 471 Query 485 SDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYG 544 S CLRAEL +AG+G+T +CPG+++T I +TT F GT EE+ RR ++ R + Sbjct 472 SQCLRAELASAGIGITAVCPGLVNTGITSTTRFV--GTGEEEQGRRRLAATALYRRRGFT 529 Query 545 PDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 P++ A IV A+++ + P+ EA A +SR+ P LR+ AR+ Sbjct 530 PERAAAGIVRAIERDAAVAPITAEARAGLVLSRLTPGLLRAAARI 574 >gi|271962091|ref|YP_003336287.1| short-chain dehydrogenase/reductase SDR [Streptosporangium roseum DSM 43021] gi|270505266|gb|ACZ83544.1| short-chain dehydrogenase/reductase SDR [Streptosporangium roseum DSM 43021] Length=602 Score = 430 bits (1106), Expect = 3e-118, Method: Compositional matrix adjust. Identities = 260/603 (44%), Positives = 345/603 (58%), Gaps = 37/603 (6%) Query 9 RLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGR 68 R V S D VR+A++ EG+P PTV+L+HG+PD+H +WD V LL +RF +VRYD RG GR Sbjct 2 RWVRSGD-VRLALFEEGDPAAPTVLLLHGYPDTHRVWDEVAGLLRDRFHVVRYDVRGAGR 60 Query 69 SSVPKPISAYTMAHFADDFDAVIGELSPGEP-VHVLAHDWGSVGVWEYLRRPGASDRVAS 127 S P+ YT H A D AV+ + G+P VH++ HDWGS+ WE + RP RV S Sbjct 61 SGAPRDGGDYTYDHLAADMAAVLDAV--GKPGVHLVGHDWGSIQGWELIGRPEIKGRVTS 118 Query 128 FTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALS 187 FTS GP D +++ G R Q LR Y+ +F PV L R + Sbjct 119 FTSFGGPGLDQAAHFMRHGRR--------AEVAGQLLRSWYIGVFQAPVAPELAWRTVMP 170 Query 188 SAAVRRNMVGD-IPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRG-RAIPIVDVPV 245 R + + I H ++TL D + + Y AN S+ RR RA P+V+ PV Sbjct 171 RVLERTMRISEGIAPRPGHPADTLREDGVNGLGLYRAN----MSTVRRTPRAEPVVETPV 226 Query 246 QLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD---LAD 302 QLI ++DP+V P WVPR+W R I AGH++ SHP+V+A + +FA+ LA+ Sbjct 227 QLIETTRDPFVSPALLASLRPWVPRMWHRRIAAGHWAQRSHPEVIARMIAEFAEHVELAE 286 Query 303 GK---------------QPSRALLRAQVGR-PRGYFGDTLVSVTGAGSGIGRETALAFAR 346 G +PSR L RA+ G RG + D LV VTGAG GIGR TA AFA Sbjct 287 GAGPAEGVGGAEGVRGVRPSRELRRARTGAGERGPYEDRLVVVTGAGGGIGRATARAFAS 346 Query 347 EGAEIVISDIDEATVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVV 406 GAE++ SDID A + TA I+A A+ Y +DV+D +E FA V EHGVPDIVV Sbjct 347 HGAEVICSDIDLAAARRTADGISATWRTAHAYRVDVADVAEMERFARLVRDEHGVPDIVV 406 Query 407 NNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYA 466 NNAGI AG FLD E + R L VNL GV++GCR F ++VERG GGHIVN++S+AA+A Sbjct 407 NNAGIAVAGPFLDHSVEDWRRTLDVNLWGVIHGCRLFAAQMVERGEGGHIVNIASLAAFA 466 Query 467 PLQSLSAYCTSKAATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEK 526 P ++L AY TSKAA M SDCLRAEL G+G+T ICPG + T I + + Sbjct 467 PSRALPAYSTSKAAVKMLSDCLRAELAGQGIGVTAICPGFVSTGIAGSATYLGGDAAPRA 526 Query 527 IDGRRGQIDKMFALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRST 586 + + D+ R Y P++VA I+ AV + +P+ V E Y +SR+ P +R Sbjct 527 REDAAARADRALTRRGYPPERVAAHILRAVHRNRPVVAVNAEGKIGYALSRISPAVMRRL 586 Query 587 ARL 589 ARL Sbjct 587 ARL 589 >gi|291002914|ref|ZP_06560887.1| short chain dehydrogenase [Saccharopolyspora erythraea NRRL 2338] Length=575 Score = 430 bits (1105), Expect = 4e-118, Method: Compositional matrix adjust. Identities = 246/584 (43%), Positives = 342/584 (59%), Gaps = 18/584 (3%) Query 10 LVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRS 69 +V + DG+ +AV+ G+PD PTVV VHG+PD H +WDGVV +LAE + +V YD RG G S Sbjct 1 MVTTGDGLSLAVWEHGDPDRPTVVAVHGYPDDHSVWDGVVRVLAEHYHVVTYDVRGAGES 60 Query 70 SVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFT 129 P+ +AY + D AV+ +SP P H+LAHDWGS+ W+ + R+ASFT Sbjct 61 DKPRERAAYRLDRLVGDLAAVLDAVSPDRPAHLLAHDWGSIQAWQAVTEEQLRARIASFT 120 Query 130 SVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSA 189 S+SGP DH ++ G RRP PR + ++Q Y+ F +PV+ L A S Sbjct 121 SISGPCLDHAGAWMRGQWRRP-TPRNLRQLLTQLAFSGYIGFFQLPVLPEL----AWYSG 175 Query 190 AVRRNMVGDIPVDQIHHSETLAR----DAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPV 245 A+ R + +D + T R D ++ Y AN S+ R R VPV Sbjct 176 AMSRLLSTVEKMDPVADG-TPPRPRIADGVRGLELYRANMMPRLSAPRVRR----TSVPV 230 Query 246 QLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQ 305 Q++ + DP+V ARWVP + R + GH+ P + P+++A + + + Sbjct 231 QVLAPTGDPFVSTPLQAAAARWVPEMRLRRLPGGHWLPRTRPELIARCAAELVENVESGA 290 Query 306 PSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTA 365 R+L +A+VG G F D LV +TGAGSGIGR TAL A GAEIV +D+DE TA Sbjct 291 EPRSLRQARVGS--GRFADRLVVITGAGSGIGRATALELAERGAEIVAADVDEKAAARTA 348 Query 366 AEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQF 425 A G A PY +DVSD EA++ FAE V GVPDIVVNNAGIG AG F DT E + Sbjct 349 ELAALLGPGATPYQVDVSDGEAMQRFAEDVRTRLGVPDIVVNNAGIGMAGAFADTTTEDW 408 Query 426 DRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFS 485 +RV+ VNL GV++GCR F +++ ERG GG IVN++S AAY P ++L AY T+KAA S Sbjct 409 ERVIDVNLWGVIHGCRLFARQMTERGEGGRIVNIASAAAYLPSRTLPAYSTTKAAVLALS 468 Query 486 DCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGP 545 CLRAEL +AG+G+T +CPG+++T I +TT F GT EE+ RR ++ R + P Sbjct 469 QCLRAELASAGIGITAVCPGLVNTGITSTTRFV--GTGEEEQGRRRLAATALYRRRGFTP 526 Query 546 DKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 ++ A IV A+++ + P+ EA A +SR+ P LR+ AR+ Sbjct 527 ERAAAGIVRAIERDAAVAPITAEARAGLVLSRLTPGLLRAAARI 570 >gi|256397823|ref|YP_003119387.1| short chain dehydrogenase [Catenulispora acidiphila DSM 44928] gi|256364049|gb|ACU77546.1| short-chain dehydrogenase/reductase SDR [Catenulispora acidiphila DSM 44928] Length=590 Score = 429 bits (1102), Expect = 8e-118, Method: Compositional matrix adjust. Identities = 243/594 (41%), Positives = 346/594 (59%), Gaps = 17/594 (2%) Query 4 TQQMSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDN 63 TQ + L + +G +++V G+P P V+LVHG+PD+ +WDG+V L + F +V YD Sbjct 2 TQDVRTLAVTVEGGKLSVRTYGDPSKPIVLLVHGYPDTQAVWDGIVAELVDDFYVVTYDT 61 Query 64 RGVGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASD 123 RG+G S P YT+ H ADD AV ++P PVH++ HDWGS+ WE + R ++ Sbjct 62 RGIGASKGPLFKHGYTLEHLADDLYAVADVVAPDRPVHLVGHDWGSIQAWEAVTRADSAQ 121 Query 124 RVASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLR 183 R S+TS+SGP DH + G+R+P P+ R++ Q L Y+ +F +PV + R Sbjct 122 RFLSYTSISGPCLDHAALWTRSGIRKP-TPKAAARSLKQALASWYIVVFHLPVGPRVAWR 180 Query 184 VALSSAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDV 243 + L+ R ++ I ++ S TL RD + V Y AN + V Sbjct 181 LGLAKQWPR--IIKAIEGTRLDPSPTLHRDGSRGVLYYRANMLPKMRRPQERSTT----V 234 Query 244 PVQLIVNSQDPYVRPYGYDQT-ARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLA- 301 PVQ++ + D +V P Q W RL+ R + GH+ + P ++A + +F + Sbjct 235 PVQVLTPTGDRFVTPALAAQAPVPWTERLYVRKVNGGHWIVVKKPALIAERIREFVQSSI 294 Query 302 ---DGKQPSRALLRA---QVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISD 355 G +P R+LLRA Q + R F D LV VTGAGSGIGR TALAFA +GA+IV++D Sbjct 295 ATPGGPEPVRSLLRAEARQGTKDRREFEDKLVVVTGAGSGIGRATALAFAEKGADIVVAD 354 Query 356 IDEATVKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAG 415 ID T + G Y Y +DVS EA+E FA V GVPD+VVNNAGIG +G Sbjct 355 IDSVAAARTVELVELLGARGYLYTVDVSSGEAMEKFANDVKETAGVPDVVVNNAGIGMSG 414 Query 416 RFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYC 475 FL T + ++++L VN+ GV++G R FG + ERG GGHIVN++S AAY P ++LSAY Sbjct 415 PFLATEVKDWEKILGVNVWGVIHGARCFGAMMRERGEGGHIVNLASAAAYTPSRTLSAYS 474 Query 476 TSKAATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQID 535 TSKAA M S+CLRAE + G+G++ ICPG I TNI TT F G E+ + R +I Sbjct 475 TSKAAVLMLSECLRAEFASYGIGVSAICPGFIATNITRTTKF--VGQSAEQQERTRQRIT 532 Query 536 KMFALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 ++ R++GPDKVA+ IV AV++ +P+ PVA EA A +SR+ P R A++ Sbjct 533 GLYRKRNFGPDKVAERIVDAVRRDRPVVPVALEARAGKAVSRLSPALARRMAKI 586 >gi|309782121|ref|ZP_07676851.1| oxidoreductase, short-chain dehydrogenase/reductase family [Ralstonia sp. 5_7_47FAA] gi|308919187|gb|EFP64854.1| oxidoreductase, short-chain dehydrogenase/reductase family [Ralstonia sp. 5_7_47FAA] Length=602 Score = 426 bits (1094), Expect = 8e-117, Method: Compositional matrix adjust. Identities = 239/575 (42%), Positives = 333/575 (58%), Gaps = 9/575 (1%) Query 15 DGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKP 74 D V +AV GNP PTVVLVHG+PD+ +W + PLLA + +V YD RG GRSS P Sbjct 32 DSVSLAVKTWGNPAHPTVVLVHGYPDNSEVWHEMAPLLARDYYVVAYDVRGAGRSSSPSG 91 Query 75 ISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGP 134 + YT A DDF AVI LSPG+PVH++AHDWGS+ WE++ R+AS+TS SGP Sbjct 92 MRNYTFARLTDDFIAVIDALSPGKPVHLIAHDWGSIQSWEFVTEERLRGRIASYTSCSGP 151 Query 135 SQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRN 194 DH+ +++ L RP P + + + Q +R Y+ LF +P+V L R+ L A R Sbjct 152 CLDHVGHWMRARLLRP-TPSSLGKMLGQLVRSWYVLLFHLPIVPELSWRLWLGRAWPR-- 208 Query 195 MVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQDP 254 ++ + I T D V Y AN+ RS + R+ + PVQ+IV + D Sbjct 209 VLRRVEKTAIVPRPTQTADGVRGVSLYRANFIRSLFTPRK----RVAHAPVQVIVPTLDK 264 Query 255 YVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLRAQ 314 YV P + +RWVP+ WRR++ A H+ P++H MA D + A+GK S AL RA+ Sbjct 265 YVSPALSEDLSRWVPQYWRREVVARHWLPVTHAARMAEMARDLIEHAEGKPESEALQRAR 324 Query 315 VGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGI 374 R L +TGAG GIGR AL FA +GA IV DI + TA I GG Sbjct 325 QHGERKPLCGKLAVITGAGGGIGRCAALEFAEQGAAIVAVDIRAEDAERTAKLIRLTGGK 384 Query 375 AYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLG 434 A+ + +DV +AE +EA + V E G DIVVNNAGIG AG +DT + R+L VN+ Sbjct 385 AWAHTVDVGNAEQMEALVDWVGKELGGADIVVNNAGIGMAGGIVDTSERDWQRILHVNVW 444 Query 435 GVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDA 494 GV++G R F +++V RG GGHI+N +S AA+AP + L+AY T+KAA M S+C+R EL Sbjct 445 GVIHGARLFAKQMVARGQGGHILNTASAAAFAPSRDLAAYATTKAAVLMLSECMRGELAG 504 Query 495 AGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIVS 554 G+G++ ICPG +T I+A+T + GT E + R + K++ LR P+ VA A+ Sbjct 505 QGIGVSAICPGFAETGIMASTVY--SGTTEAQQAQLRARATKLYQLRGLKPETVAKAMFG 562 Query 555 AVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 A++ KP+ + EA++ ISR R AR+ Sbjct 563 AMQHNKPVVTIGIEAHSSRFISRYAQWLSRLIARV 597 >gi|187928384|ref|YP_001898871.1| short chain dehydrogenase [Ralstonia pickettii 12J] gi|187725274|gb|ACD26439.1| short-chain dehydrogenase/reductase SDR [Ralstonia pickettii 12J] Length=602 Score = 425 bits (1093), Expect = 9e-117, Method: Compositional matrix adjust. Identities = 241/582 (42%), Positives = 339/582 (59%), Gaps = 10/582 (1%) Query 8 SRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVG 67 +R+V S V + V G+P PTVVLVHG+PD+ +W V PLLA + ++ YD RG G Sbjct 26 ARMVQS-GSVSLTVETWGDPAHPTVVLVHGYPDNSEVWHEVAPLLARDYYVIAYDVRGAG 84 Query 68 RSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVAS 127 RSS PK + YT A DDF AVI LSPG+PVH++AHDWGS+ WE++ R+AS Sbjct 85 RSSSPKGMRNYTFARLTDDFIAVIDALSPGKPVHLIAHDWGSIQSWEFVTEARLRGRIAS 144 Query 128 FTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALS 187 +TS SGP DH+ +++ L RP P + + + Q +R Y+ LF +P+V L R+ L Sbjct 145 YTSCSGPCLDHVGHWMRARLLRP-TPSSLGKMLGQLVRSWYVLLFHLPIVPELSWRLWLG 203 Query 188 SAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQL 247 A R ++ + I T D V Y AN+ RS + R+ + PVQ+ Sbjct 204 RAWPR--VLRRVEKTAIVPRATQTADGVRGVSLYRANFIRSLFTPRK----RVAHAPVQV 257 Query 248 IVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPS 307 IV + D YV P + +RWVP+ WRR++ A H+ P++H +A + + A+GK S Sbjct 258 IVPTLDKYVSPALSEDLSRWVPQYWRREVVARHWLPVTHAARLAEMARELIEHAEGKPES 317 Query 308 RALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAE 367 AL RA+ R L +TGAGSGIGR AL FA +GA IV DI + TA Sbjct 318 EALQRARQHGDRKPLCGKLAVITGAGSGIGRCAALEFAEQGAAIVAVDIRAEDAERTAKL 377 Query 368 IAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDR 427 I GG A+ + +DV +AE +EA + V E G DIVVNNAGIG AG +DT + R Sbjct 378 IRLTGGKAWAHTVDVGNAEQMEALVDWVGKELGGADIVVNNAGIGMAGGIVDTSERDWQR 437 Query 428 VLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDC 487 +L VN+ GV++G R F +++V RG GGHI+N +S AA+AP + L+AY T+KAA M S+C Sbjct 438 ILHVNVWGVIHGARLFAKQMVARGQGGHILNTASAAAFAPSRDLAAYATTKAAVLMLSEC 497 Query 488 LRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDK 547 +R EL G+G++ ICPG +T I+A+T + GT E + R + K++ LR P+ Sbjct 498 MRGELAGQGIGVSAICPGFAETGIMASTVY--TGTTEAQQAQLRARATKLYQLRGLKPET 555 Query 548 VADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 VA A+ SAV+ KP+ + EA++ ISR R AR+ Sbjct 556 VAKAMFSAVQHNKPVVTIGIEAHSSRFISRYAQWLSRLIARV 597 >gi|326384658|ref|ZP_08206336.1| short chain dehydrogenase [Gordonia neofelifaecis NRRL B-59395] gi|326196625|gb|EGD53821.1| short chain dehydrogenase [Gordonia neofelifaecis NRRL B-59395] Length=590 Score = 422 bits (1086), Expect = 6e-116, Method: Compositional matrix adjust. Identities = 256/574 (45%), Positives = 332/574 (58%), Gaps = 17/574 (2%) Query 24 EGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPISAYTMAHF 83 E PD P V+LVHG+PD+H LWD V P LAE FR+ YD RG G SS P + AY + Sbjct 26 ETTPDKPVVLLVHGWPDTHHLWDLVAPQLAEHFRVYAYDTRGFGDSSRPSDVPAYRLDAL 85 Query 84 ADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQDHLVNYV 143 A+D AV +SP H++AHDWGSV WE + PGA D +ASFTSVSGP+ D L + Sbjct 86 AEDMFAVCRAVSPDGKTHIVAHDWGSVQAWETVTTPGAEDAIASFTSVSGPNLDFLGEWA 145 Query 144 YGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNMVGDI---P 200 G + RP P +A+SQ +Y A F VP + R A S V + I P Sbjct 146 RGKMARP-TPSNVGQALSQVASSAYTAFFQVPGASDAFFR-AFGSDRVWTEFLHFIEGTP 203 Query 201 VDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPI-VDVPVQLIVNSQDPYVRPY 259 + TL D +K Y AN + R P VPV IVN +D +RP Sbjct 204 RENARFGPTLREDMISGLKLYRANI-----RGKLARPNPRPTRVPVLEIVNDRDIALRPA 258 Query 260 GYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD-LADGKQPS-RALLRAQVGR 317 Y++T RLWR+ GH+ P ++P +AA +F + +A G + + RA+V Sbjct 259 IYERTHTHAERLWRKRSTTGHWLPYTNPDYLAATAIEFIEKIATGSSSAPNTIDRARVTG 318 Query 318 PRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYP 377 P L +TGAGSGIGRETA A A GAE+V++DID TV++TA E A+G A Sbjct 319 PAPELIGKLAVITGAGSGIGRETAYALADLGAELVLADIDLETVEETAIECKAKGVPATA 378 Query 378 YVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVV 437 Y LDVSD AV FA+ V HGV DIV+NNAGI AG L EQ DR+LA+NL GV+ Sbjct 379 YRLDVSDTTAVTRFADEVRDAHGVADIVINNAGIAVAGSALAASDEQVDRLLAINLRGVI 438 Query 438 NGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAGV 497 +G RAFG+++VERGTGG IVN++S AA+ + L Y SKA MFS+ LRAEL + Sbjct 439 SGSRAFGKQMVERGTGGQIVNLASAAAFTLSRDLGLYSASKAGVLMFSEALRAELAEHRI 498 Query 498 GLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIVSAVK 557 G+T ICPG++ TNI A+T F A DE R ++D +A R++ PD+VA IVSA++ Sbjct 499 GVTAICPGIVHTNITASTEF-AGAADEAAT---RKKVDGFYAKRNFTPDRVASDIVSAIR 554 Query 558 KKKPIRPVAPEAYALYGISRVLPQALRSTARLRV 591 K K + PV PEA Y + R LP A R AR ++ Sbjct 555 KNKAVVPVTPEAEFGYRVYRFLPWAARIGARQKL 588 >gi|120404547|ref|YP_954376.1| short chain dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119957365|gb|ABM14370.1| short-chain dehydrogenase/reductase SDR [Mycobacterium vanbaalenii PYR-1] Length=538 Score = 422 bits (1086), Expect = 7e-116, Method: Compositional matrix adjust. Identities = 225/348 (65%), Positives = 266/348 (77%), Gaps = 0/348 (0%) Query 241 VDVPVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADL 300 VDVPVQLIV DP+V P+ YD + V RLWRRDIK G SP SHPQV+A AV D Sbjct 186 VDVPVQLIVPDHDPHVGPHVYDGMSASVSRLWRRDIKTGDLSPGSHPQVLARAVDQLVDH 245 Query 301 ADGKQPSRALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEAT 360 G R LLRAQVGR R FGDTLVSVTGA SGIGRETALAFAR GA++VISD+DEA Sbjct 246 LGGAPAPRELLRAQVGRARKVFGDTLVSVTGAASGIGRETALAFARAGADVVISDVDEAG 305 Query 361 VKDTAAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDT 420 ++ TA + A G A+ Y +DV+DA AVEA AE V A HGVPDIVVNNAG+G AG FLDT Sbjct 306 LEQTARLVTAAGAAAHSYTVDVADAAAVEAMAELVCAAHGVPDIVVNNAGVGHAGFFLDT 365 Query 421 PAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAA 480 PAE+FDRVL +N GGVVNGCR++G+RLV+RGTGGHIVNV+SMA+Y P+ ++AYCTSKAA Sbjct 366 PAEEFDRVLGINFGGVVNGCRSWGRRLVDRGTGGHIVNVASMASYTPVNVMNAYCTSKAA 425 Query 481 TYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFAL 540 +MFSDCLRAELD+AG+G+TTICPGVI TNIV TT F P + + R + + FA+ Sbjct 426 VFMFSDCLRAELDSAGIGVTTICPGVIGTNIVDTTRFSLPEARRDDAESIRRRARQGFAV 485 Query 541 RSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTAR 588 R GPDKVA AIV+AV+K KP+RPV EAY +YG++ LPQA+RS AR Sbjct 486 RRVGPDKVAKAIVAAVQKNKPVRPVTTEAYLVYGVAHALPQAMRSAAR 533 Score = 167 bits (422), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 93/158 (59%), Positives = 109/158 (69%), Gaps = 3/158 (1%) Query 9 RLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGR 68 R V+S DGVRIAV +GNPDGPT+VLVHG D+H +WD VV LLA+RFRIV YD RG G Sbjct 5 RFVESSDGVRIAVSEQGNPDGPTLVLVHGLRDTHRVWDPVVALLADRFRIVAYDTRGAGN 64 Query 69 SSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASF 128 S PK SAYT+ FADDF AV + PVHVLAH WG+ GVW+YL+R A +RVAS Sbjct 65 SGAPKQTSAYTVDRFADDFAAVAAAVGGDTPVHVLAHGWGAAGVWQYLKRADAPERVASL 124 Query 129 TSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRL 166 TSVSGPS +H+ YV L PR F+R Q +RL Sbjct 125 TSVSGPSPEHVAGYVRAALT---SPRRFVRGAGQLVRL 159 >gi|241662960|ref|YP_002981320.1| short chain dehydrogenase [Ralstonia pickettii 12D] gi|240864987|gb|ACS62648.1| short-chain dehydrogenase/reductase SDR [Ralstonia pickettii 12D] Length=602 Score = 422 bits (1086), Expect = 7e-116, Method: Compositional matrix adjust. Identities = 238/573 (42%), Positives = 333/573 (59%), Gaps = 9/573 (1%) Query 17 VRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPIS 76 V +AV GNP PTVVLVHG+PD+ +W + PLLA + +V YD RG GRSS P + Sbjct 34 VSLAVKTWGNPAHPTVVLVHGYPDNSEVWHEMAPLLARDYYVVAYDVRGAGRSSSPSGMR 93 Query 77 AYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQ 136 YT A DDF AVI LSPG+PVH++AHDWGS+ WE++ R+AS+TS SGP Sbjct 94 NYTFARLTDDFIAVIDALSPGKPVHLIAHDWGSIQSWEFVTEERLRGRIASYTSCSGPCL 153 Query 137 DHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNMV 196 DH+ +++ L RP P + + + Q +R Y+ LF +P+V L R+ L A R ++ Sbjct 154 DHVGHWMRARLLRP-TPSSLGKMLGQLVRSWYVLLFHLPIVPELSWRLWLGRAWPR--VL 210 Query 197 GDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQDPYV 256 + I T D V Y AN+ RS + R+ + PVQ+IV + D YV Sbjct 211 RRVEKTAIVPRPTQTADGVRGVSLYRANFIRSLFTPRK----RVAHAPVQVIVPTLDKYV 266 Query 257 RPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLRAQVG 316 P + +RWVP+ WRR++ A H+ P++H MA + + A+GK S AL RA+ Sbjct 267 SPALSEDLSRWVPQYWRREVVARHWLPVTHAARMAEMACELIEHAEGKPESEALQRARPQ 326 Query 317 RPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAY 376 R L +TGAG GIGR AL FA +GA IV DI + TA I GG A+ Sbjct 327 GERKPLSGKLAVITGAGGGIGRCAALEFAEQGAAIVAVDIRAEDAERTAKLIRLTGGKAW 386 Query 377 PYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGV 436 + +DV +AE +EA + V + G DIVVNNAGIG AG +DT + R+L VN+ GV Sbjct 387 AHTVDVGNAEQMEALVDWVGKDLGGADIVVNNAGIGMAGGIVDTSERDWQRILHVNVWGV 446 Query 437 VNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAG 496 ++G R F +++V RG GGHI+N +S AA+AP + L+AY T+KAA M S+C+R EL G Sbjct 447 IHGARLFAKQMVARGQGGHILNTASAAAFAPSRDLAAYATTKAAVLMLSECMRGELAGQG 506 Query 497 VGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIVSAV 556 +G++ ICPG +T I+A+T + GT E + R + K++ LR P+ VA A+ SAV Sbjct 507 IGVSAICPGFAETGIMASTVY--SGTTEAQQAQLRARATKLYQLRGLKPETVAKAMFSAV 564 Query 557 KKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 + KP+ + EA++ ISR R AR+ Sbjct 565 QHNKPVVTIGIEAHSSRFISRYAQWLSRLIARV 597 >gi|290959066|ref|YP_003490248.1| oxidoreductase [Streptomyces scabiei 87.22] gi|260648592|emb|CBG71703.1| putative oxidoreductase [Streptomyces scabiei 87.22] Length=594 Score = 422 bits (1085), Expect = 8e-116, Method: Compositional matrix adjust. Identities = 249/584 (43%), Positives = 342/584 (59%), Gaps = 26/584 (4%) Query 15 DGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKP 74 DGV + V G+P+ PTV+LVHG+PD+ +W V P LAERF +V YD RG G S+ P+P Sbjct 24 DGVELCVAELGDPEQPTVLLVHGYPDTKEVWSEVAPRLAERFHVVLYDVRGHGGSTAPEP 83 Query 75 I-SAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSG 133 + +T+ DDF AV +SPG PVH++ HDWGSV WE++ R+ASFTS+SG Sbjct 84 LRGGFTLEKLTDDFLAVADAVSPGRPVHLVGHDWGSVQGWEFVTVERTEGRIASFTSMSG 143 Query 134 PSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSS---AA 190 PS DH+ +++ ++RP PR + + Q R Y+ + PV+ L R L Sbjct 144 PSLDHMGHWIKRRVKRP-TPRRIGQLLGQGARSWYVYVLHTPVLPELAWRGPLGRHWPGL 202 Query 191 VRRNMV---GDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQL 247 VRR GD P S +L DAAH Y N S R R PVQL Sbjct 203 VRRAERLPRGDYP------SPSLPTDAAHGAWLYRDNMRTRLS---RPRDDAYAHAPVQL 253 Query 248 IVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPS 307 I D ++ +D W P+L RR + A H+ P + P +A+ + +F +G +P+ Sbjct 254 ITPLGDQFLSEQLHDDLESWAPQLTRRTLPAKHWIPRTRPDQLASWITEFVSATEGGRPA 313 Query 308 RALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAE 367 R FG LV VTGA +GIGR TA FA GA ++ D+D TA E Sbjct 314 PVATGTYTER----FGGQLVLVTGAAAGIGRATAFTFAEAGARVIAVDLDAEGASRTA-E 368 Query 368 IAARGGI--AYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQF 425 ++ G A+ V+DVSD +A+ AE+V+AE+GV D++VNNAGIG +G FLDT AE + Sbjct 369 LSRLIGAPEAWAEVVDVSDEQAMVKLAEKVAAEYGVVDVLVNNAGIGLSGSFLDTTAEDW 428 Query 426 DRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFS 485 + L VNL GV++GCR FG+++VERG GGHIVN +S AAY P +SL AY TSKAA M S Sbjct 429 RKALDVNLWGVIHGCRLFGRQMVERGQGGHIVNTASAAAYLPSRSLPAYSTSKAAVLMLS 488 Query 486 DCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGP 545 +CLRAEL G+G++ ICPG+++T I +T F +EE+ RR K++ LR+Y P Sbjct 489 ECLRAELAGRGIGVSAICPGIVNTGITSTARFAGVAPEEEQRRQRRAA--KLYGLRNYPP 546 Query 546 DKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 +KVA A++ AV + + PV PEA+ +SR P+ALR+ ARL Sbjct 547 EKVAQAVLRAVVHDQAVVPVTPEAHGGRFLSRFAPRALRALARL 590 >gi|302535638|ref|ZP_07287980.1| short chain dehydrogenase [Streptomyces sp. C] gi|302444533|gb|EFL16349.1| short chain dehydrogenase [Streptomyces sp. C] Length=590 Score = 421 bits (1083), Expect = 2e-115, Method: Compositional matrix adjust. Identities = 254/581 (44%), Positives = 341/581 (59%), Gaps = 13/581 (2%) Query 13 SPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVP 72 S G+ + V G PTV+LVHG+PDS +W V LA+RF +V YD RG GRSS P Sbjct 15 STGGIELCVVELGEAGRPTVLLVHGYPDSKEVWSEVAERLADRFHVVLYDVRGHGRSSAP 74 Query 73 KPI-SAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSV 131 P+ +T+ DDF AV +SP PVH++ HDWGSV WE+ R+ASFTS+ Sbjct 75 VPLRGGFTLEKLTDDFLAVADAVSPDRPVHLVGHDWGSVQGWEFATVARTEGRIASFTSM 134 Query 132 SGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAV 191 SGPS DH +++ +RRP PR + + Q LR Y+ + PV+ L R L Sbjct 135 SGPSLDHFGHWIKQRMRRP-SPRRAAQLLGQGLRSWYVGMLHTPVLPELAWRGPLGKRWP 193 Query 192 RRNMVGD-IPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVN 250 + + IPV + + +L DAAH Y N S R R VPVQLIV Sbjct 194 KLMERSEGIPVGG-YPTASLPSDAAHGAWLYRDNVRARMS---RPRPDAYAHVPVQLIVP 249 Query 251 SQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRAL 310 + D ++ YD RW P L RR + A H+ P + P +AA + DF A + +RA Sbjct 250 TGDVFLSERLYDDVERWAPGLVRRTLPAKHWIPRTRPDQVAAWIADFVT-AREEPAARAP 308 Query 311 LRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAA 370 R G+ FG LV VTGA SGIGR TA AFA GA +V D D TA E+A Sbjct 309 ERRAPGKYADRFGGQLVLVTGAASGIGRATAFAFAEAGARVVAVDRDAEGAARTA-EMAR 367 Query 371 RGGI--AYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRV 428 G A+ +DVSD +A+E A +V+AE+G+ D++VNNAGIG +G FL+T +E + +V Sbjct 368 LVGAPEAWGECVDVSDEQAMEKLAAKVAAEYGIVDVLVNNAGIGLSGAFLETASEDWKKV 427 Query 429 LAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL 488 L VNL GVV+GCR FG+++ ERG GGHIVN +S AAY P ++L AY TSKAA M S+CL Sbjct 428 LDVNLWGVVHGCRIFGRQMAERGQGGHIVNTASAAAYLPSRTLPAYSTSKAAVLMLSECL 487 Query 489 RAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKV 548 RAEL + +G++ ICPG+++TNI AT+ F EEK R+ + +++ LR++ P+KV Sbjct 488 RAELASKSIGVSAICPGIVNTNITATSRFAGVDAAEEK--RRQERSSRLYGLRNFPPEKV 545 Query 549 ADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 ADAI+ AV K + + PV PE+ A +SR P LR ARL Sbjct 546 ADAILLAVVKNRAVVPVTPESKAALWMSRFAPNTLRRIARL 586 >gi|206588570|emb|CAQ35533.1| alpha/beta hydrolase fold;short-chain dehydrogenase/reductase sdr; protein [Ralstonia solanacearum MolK2] Length=599 Score = 420 bits (1080), Expect = 4e-115, Method: Compositional matrix adjust. Identities = 243/582 (42%), Positives = 339/582 (59%), Gaps = 10/582 (1%) Query 8 SRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVG 67 R V S D V +AV G+P PTVVLVHG+PD+ +W + LLA + ++ YD RG G Sbjct 23 ERTVQSGD-VTLAVKTWGDPARPTVVLVHGYPDNSEVWHTMARLLAPDYYVIAYDVRGAG 81 Query 68 RSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVAS 127 RSS PK + YT A DDF AVI LSP +PVH++AHDWGS+ W ++ R+AS Sbjct 82 RSSAPKGLRHYTFARLTDDFIAVIDALSPTKPVHLVAHDWGSIQGWTFVTEERLRGRIAS 141 Query 128 FTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALS 187 +TS SGP DH+ +++ L RP P + + + Q +R Y+ LF +PV+ L R+ L Sbjct 142 YTSCSGPCLDHVGHWMRTRLLRP-TPASLGKLLGQLVRSWYVLLFHLPVLPELSWRLWLG 200 Query 188 SAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQL 247 A ++ + I T D H V Y AN+ RS + R+ A PVQ+ Sbjct 201 RAWP--GLLRRVEKTAIAPRATQTADGLHGVSLYRANFIRSLFAPRKRYA----HAPVQV 254 Query 248 IVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPS 307 IV + D YV P + +RWVPR WRR+I A H+ P++HP+ MA + + A+G+ S Sbjct 255 IVPTLDKYVSPALSEDLSRWVPRYWRREIVARHWLPVTHPERMAEMARELIEHAEGRPES 314 Query 308 RALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAE 367 AL RA++G R L +TGAGSGIGR AL FA +GA IV DI + TA Sbjct 315 EALRRARMGGVRKPLAGKLAVITGAGSGIGRCAALEFAGQGASIVAVDIRGDDAERTATL 374 Query 368 IAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDR 427 + GG A+ DV AE + A A+ V AE G DIVVNNAGIG AG +DT + R Sbjct 375 VRLTGGRAWARTADVGSAEQMTALADWVGAELGGADIVVNNAGIGMAGGIVDTTERDWQR 434 Query 428 VLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDC 487 VL VNL GV++G R F +++V RG GGHIVN +S AA++P + L+AY T+KAA M S+C Sbjct 435 VLHVNLWGVIHGARLFARQMVARGQGGHIVNTASAAAFSPSRDLAAYATTKAAVLMLSEC 494 Query 488 LRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDK 547 +R EL G+G++ ICPG +T I+A+T + GT E + R + +++ R P+ Sbjct 495 MRGELAGQGIGVSAICPGFAETGIMASTVY--AGTTEAQQAALRKRATQLYQRRGLKPEA 552 Query 548 VADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 VA A++ AV + +PI + EA+++ +SR P R AR+ Sbjct 553 VARAMLRAVLRNQPIVSIGIEAHSMRLVSRYAPWLGRLMARV 594 >gi|336177893|ref|YP_004583268.1| Estradiol 17-beta-dehydrogenase [Frankia symbiont of Datisca glomerata] gi|334858873|gb|AEH09347.1| Estradiol 17-beta-dehydrogenase [Frankia symbiont of Datisca glomerata] Length=606 Score = 420 bits (1079), Expect = 4e-115, Method: Compositional matrix adjust. Identities = 267/613 (44%), Positives = 354/613 (58%), Gaps = 36/613 (5%) Query 7 MSRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAER-FRIVRYDNRG 65 M R GV +AVY +GNP GPTV+LVHG+PD+H +WD V LA +VRYD RG Sbjct 1 MRRRTVVSAGVPLAVYEQGNPAGPTVLLVHGYPDTHWVWDDVAAALAADGHHVVRYDVRG 60 Query 66 VGRSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRV 125 G S K Y + ADD AV +SP VH+ AHDWGS+ WE + P A+ R+ Sbjct 61 AGASGAAKGACGYRLPQLADDLFAVADAVSPHRAVHLAAHDWGSIQAWEAVTDPRAAGRI 120 Query 126 ASFTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVA 185 AS+TS+SGP DH+ ++ L RP PR + ++Q Y+ +F +P++AP + R+ Sbjct 121 ASYTSLSGPCLDHVGHWARRRLARP-TPRHLGQLLTQAAHSWYIGVFHLPLLAPAVWRLG 179 Query 186 LSS--AAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDV 243 L++ V + G IP H TLA DA H + Y AN R R P V Sbjct 180 LAARWGYVLASTEGVIPRTS-HPQPTLATDAVHGIALYRANMLPHLL---RPRQRPTA-V 234 Query 244 PVQLIVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPM-SHPQVMAAAVHDFADLAD 302 PVQLI ++D YV P D RWVP LWRR + AGH+S + +A + + A AD Sbjct 235 PVQLITLARDRYVSPALGDDLDRWVPHLWRRTLTAGHWSALLEKGPTVAQMIKEIAAHAD 294 Query 303 GKQPSRALLRAQV-----------------------GRPRGYFGDTLVSVTGAGSGIGRE 339 G + AL RA V G R F L VTG GSGIGR Sbjct 295 GAPAAPALERAAVSSRERAAGPRRPQRPRLRWCRGPGLERAAFAGKLAVVTGGGSGIGRA 354 Query 340 TALAFAREGAEIVISDIDEATVKDTAAEIAARGG-IAYPYVLDVSDAEAVEAFAERVSAE 398 TALAFA GA +V+ D+D A+ + T G A+ Y +DV+D+ AV+ FA V+A Sbjct 355 TALAFAEHGAAVVVCDLDLASAERTVELTRLLGAPAAHAYRVDVADSAAVDTFAREVAAA 414 Query 399 HGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVN 458 HGVPDIVVNNAG+G G FL T +++ +L VNLGGVV+GCRAF +VERG GGHIVN Sbjct 415 HGVPDIVVNNAGVGHGGTFLQTTEKEWQHILEVNLGGVVHGCRAFATLMVERGEGGHIVN 474 Query 459 VSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFH 518 VSS AAY P + L+AY TSKAA YM SDCLRAEL AG+G++TICPG+++TNI T+ F Sbjct 475 VSSAAAYLPSKVLAAYATSKAAVYMLSDCLRAELAPAGIGVSTICPGLVNTNITRTSTF- 533 Query 519 APGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRV 578 G + +D R + ++A R++ P+KVA I+ AV++ + + PV EA A +SR+ Sbjct 534 -SGRSADGLDATRDRFAALYARRNFPPEKVAWQILRAVRENRAVVPVTVEARAGRVLSRL 592 Query 579 LPQALRSTARLRV 591 P R+ AR+ + Sbjct 593 SPALTRAAARIDI 605 >gi|110835557|ref|YP_694416.1| short chain dehydrogenase [Alcanivorax borkumensis SK2] gi|110648668|emb|CAL18144.1| oxidoreductase, putative [Alcanivorax borkumensis SK2] Length=581 Score = 420 bits (1079), Expect = 4e-115, Method: Compositional matrix adjust. Identities = 235/585 (41%), Positives = 339/585 (58%), Gaps = 25/585 (4%) Query 13 SPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVP 72 S +G+ +AV PTVVLVHG+PD+ +W+ V L+ F++V YD RG G SS P Sbjct 10 SRNGIDLAVRTWSPDKSPTVVLVHGYPDASHVWEKVAERLSRDFKVVAYDVRGAGNSSTP 69 Query 73 KPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVS 132 K +AY ++ D AV+ + P E VH++ HDWGSV WE + P A R+AS+T++S Sbjct 70 KNRAAYKLSQLRGDLHAVMDAVCPDEKVHLVGHDWGSVQTWESVTEPNAEHRIASYTTLS 129 Query 133 GPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSA--- 189 GP DH+ ++ LR + ++Q Y+ F +PV+AP L +V L+ Sbjct 130 GPCLDHVGQWMNARLRE----QKIGAVLNQLAHSWYIGAFQLPVLAPALWKVGLAKVWPQ 185 Query 190 AVRR--NMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQL 247 +RR N+ + V Q+ +D H ++ Y AN R VPVQL Sbjct 186 VLRRTENLYSEASVTQL-------QDGTHGIELYRANMLPCLLKPRER----YTKVPVQL 234 Query 248 IVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPM-SHPQVMAAAVHDFADLADGKQP 306 IV +D YVRP + +W +LWRR++ GH+ P+ HP V A + +F +G Sbjct 235 IVAREDNYVRPAMLEDLPQWTEQLWRRELDCGHWGPLLQHPDVTANWIREFIHHIEGAPA 294 Query 307 SRALLRAQV--GRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDT 364 + L R++V G P G V +TGAGSGIGRETALAFAR GA +V +DI+ T Sbjct 295 AGPLQRSKVTTGHPTGPDSGKRVIITGAGSGIGRETALAFARRGALVVCTDINSEEAAAT 354 Query 365 AAEIAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQ 424 A I A GG A DVS+ ++EA A V E G PDIVVNNAGIG +G LDT + Sbjct 355 ARTITAEGGEALSRKCDVSNTRSMEALATWVEKELGAPDIVVNNAGIGLSGSLLDTSVKD 414 Query 425 FDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMF 484 + +VL VNL GV++G R F ++++++G GHIVN++S AA+ P + L AY TSK+A MF Sbjct 415 WQQVLGVNLWGVIHGSRLFARQMIDQGRAGHIVNIASAAAFMPSRMLPAYATSKSAVLMF 474 Query 485 SDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYG 544 S+CLRAE+D +G++ ICPG+I+T I T F G D+++ R+ +K++ R++ Sbjct 475 SECLRAEMDEHNIGVSAICPGIINTPITRNTRF--VGVDDDEQSRRQKNAEKLYQRRAFT 532 Query 545 PDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 PD+VA AIV AV+K + + PV+PEA + + R P R+ A++ Sbjct 533 PDRVAQAIVEAVEKNRAVVPVSPEALGMQWLGRFTPSLARNLAQV 577 >gi|254384844|ref|ZP_05000181.1| short chain dehydrogenase [Streptomyces sp. Mg1] gi|194343726|gb|EDX24692.1| short chain dehydrogenase [Streptomyces sp. Mg1] Length=590 Score = 419 bits (1076), Expect = 9e-115, Method: Compositional matrix adjust. Identities = 248/581 (43%), Positives = 338/581 (59%), Gaps = 13/581 (2%) Query 13 SPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVP 72 S GV + V G D PTVVLVHG+PDS +W V LA RF +V YD RG GRS+ P Sbjct 15 STGGVELCVVELGEADRPTVVLVHGYPDSKEVWSEVAERLATRFHVVLYDVRGHGRSTAP 74 Query 73 KPI-SAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSV 131 P+ +T+ DDF AV +SP PVH++ HDWGSV WE+ R+ASFTS+ Sbjct 75 VPLRGGFTLEKLTDDFLAVADAVSPDRPVHLVGHDWGSVQGWEFATTARTEGRIASFTSM 134 Query 132 SGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAV 191 SGPS DH +++ + RP PR + ++Q + Y+ + PV+ L R L Sbjct 135 SGPSLDHFGHWIKKRMARP-TPRRAAQLLNQGAKSWYVYMLHTPVLPELAWRGPLGKRWP 193 Query 192 R-RNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVN 250 + + +P + + +L DAAH Y N S RR RA VPVQLI Sbjct 194 KILQRIEKVPSGS-YPTASLPSDAAHGAWLYRDNVR---SRMRRPRADAYAHVPVQLITP 249 Query 251 SQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQP-SRA 309 + D ++ YD W P L RR + A H+ P + P +AA + DF + ++P +RA Sbjct 250 TGDAFLSERLYDDLELWAPDLLRRTLPAKHWVPRTRPDQLAAWITDF--VTSREEPATRA 307 Query 310 LLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIA 369 + GR FG LV VTGA SGIGR TA AFA GA +V D D TA Sbjct 308 PEQRAPGRYADRFGGQLVLVTGAASGIGRATAFAFAEAGARVVCVDRDAEGAARTADMAR 367 Query 370 ARGGI-AYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRV 428 G A+ +DVSD +A+E A +V+AE+G+ D++VNNAGIG +G FL+T +E + +V Sbjct 368 LVGAAEAWGECVDVSDEQAMEKLAAKVAAEYGIVDVLVNNAGIGLSGPFLETTSEDWKKV 427 Query 429 LAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCL 488 L VNL GV++GCR FG+++ ERG GGHIVN +S AAY P ++L AY TSKAA M S+CL Sbjct 428 LDVNLWGVIHGCRIFGKQMAERGQGGHIVNTASAAAYLPSRTLPAYSTSKAAVLMLSECL 487 Query 489 RAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKV 548 RAEL A +G++ ICPG+++TNI AT+ F G DE + R+ + +++ LR++ P+KV Sbjct 488 RAELAAQSIGVSAICPGIVNTNITATSRF--AGVDEAEEKRRQARSSRLYGLRNFPPEKV 545 Query 549 ADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 ADAIV AV + + + PV PE+ +SR P LR ARL Sbjct 546 ADAIVLAVVRNQAVVPVTPESKGALWMSRFAPGTLRRLARL 586 >gi|29830795|ref|NP_825429.1| short chain dehydrogenase [Streptomyces avermitilis MA-4680] gi|29607908|dbj|BAC71964.1| putative dehydrogenase [Streptomyces avermitilis MA-4680] Length=584 Score = 417 bits (1071), Expect = 3e-114, Method: Compositional matrix adjust. Identities = 243/578 (43%), Positives = 338/578 (59%), Gaps = 16/578 (2%) Query 16 GVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPI 75 G+ + V G+ PTVVLVHG+PDS +W V L+ERF +V YD RG GRS+ P+P+ Sbjct 15 GIELCVAELGDETQPTVVLVHGYPDSKEVWSEVAGRLSERFHVVLYDVRGHGRSTAPQPL 74 Query 76 -SAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGP 134 +T+ DDF AV +SP PVH++ HDWGSV WE++ R+ASFTS+SGP Sbjct 75 RGGFTLEKLTDDFLAVADAVSPDRPVHLVGHDWGSVQSWEFVTVKRTEGRIASFTSMSGP 134 Query 135 SQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVR-R 193 S DH +++ ++RP PR + + Q + Y+ L PV+ L R L + Sbjct 135 SLDHFGHWIKRRVKRP-TPRRVGQLLGQGAKSWYVYLLHTPVLPELAWRGPLGRRWPKIL 193 Query 194 NMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQD 253 V +P D + + +L DAAH Y N S R R PVQL+ D Sbjct 194 QRVEKVPADG-YPTPSLPSDAAHGAWLYRDNVRARLS---RPRTDAYAHAPVQLVTPLGD 249 Query 254 PYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLRA 313 ++ YD+ W P+L RR + A H+ P + P +A+ + +F ++G +P+ Sbjct 250 AFLSEKLYDELELWAPQLVRRTLPAKHWIPRTRPDQLASWITEFVIASEGGRPAPVASGP 309 Query 314 QVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGG 373 R FG LV VTGAGSGIGR TA AFA GA +V D + TA E++ G Sbjct 310 YADR----FGGQLVLVTGAGSGIGRATAYAFAEAGARVVAVDRNAEGAARTA-EMSRLIG 364 Query 374 I--AYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAV 431 A+ +DVSD +A+E AE+V+ E+GV D++VNNAGIG +G F DT AE + +VL V Sbjct 365 APDAWAETVDVSDEQAMEKLAEKVATEYGVVDVLVNNAGIGLSGSFFDTTAEDWRKVLDV 424 Query 432 NLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAE 491 NL GV++GCR FG+++ ERG GGHIVN +S AAY P ++L AY TSKAA M S+CLRAE Sbjct 425 NLWGVIHGCRLFGKQMAERGQGGHIVNTASAAAYQPSKALPAYSTSKAAVLMLSECLRAE 484 Query 492 LDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVADA 551 L G+G++ ICPG + TNI +T F +EEK +R +++ LR Y P+KVADA Sbjct 485 LAGQGIGVSAICPGFVHTNITSTARFAGVAAEEEKRRQKRAA--RLYRLRGYPPEKVADA 542 Query 552 IVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 ++ AV + + + PV PEA + +SR P+ALR+ ARL Sbjct 543 VLRAVVRNQAVVPVTPEARGAHLMSRFAPRALRAIARL 580 >gi|21222359|ref|NP_628138.1| short chain dehydrogenase [Streptomyces coelicolor A3(2)] gi|3928730|emb|CAA22226.1| putative oxidoreductase [Streptomyces coelicolor A3(2)] Length=585 Score = 415 bits (1067), Expect = 1e-113, Method: Compositional matrix adjust. Identities = 251/586 (43%), Positives = 333/586 (57%), Gaps = 30/586 (5%) Query 16 GVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPI 75 GV + V G+P PTVVLVHG+PDS +W V LA RF +V YD RG GRSS P P+ Sbjct 16 GVELCVAELGDPRRPTVVLVHGYPDSKEVWSEVAARLAGRFHVVLYDVRGHGRSSAPSPL 75 Query 76 -SAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGP 134 +T+ DDF AV +SP PVH++ HDWGSV WE++ R+ASFTS+SGP Sbjct 76 RGGFTLEKLTDDFLAVADAVSPDRPVHLVGHDWGSVQSWEFVTVKRTEGRIASFTSMSGP 135 Query 135 SQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSS------ 188 S DH +++ LRRP PR + + Q + Y+ L PV+ L R L Sbjct 136 SLDHFGHWINKRLRRP-TPRRVGQLLGQGAKSWYVYLLHTPVLPELAWRGPLGKRWPGIL 194 Query 189 AAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLI 248 V + GD P + +L DAAH Y N RR R PVQLI Sbjct 195 ERVEKVPGGDYP------TASLPSDAAHGAWLYRDNVRPRL---RRPREDAYAHAPVQLI 245 Query 249 VNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLA-DGKQPS 307 D ++ YD W PRL RR + A H+ P + P +A + +F DG+ + Sbjct 246 TPLGDAFLSERLYDGLELWAPRLTRRTLPAKHWVPRTRPDRLADWITEFVTATEDGRSET 305 Query 308 RALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAE 367 A G+ FG LV VTGAGSGIGR TA AFA GA +V D D TA Sbjct 306 -----AANGKYADRFGGQLVLVTGAGSGIGRATAFAFAEAGARVVAVDRDAEAAARTAEL 360 Query 368 ---IAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQ 424 I AR A+ +DVSD +A+E A RV+AE+GV D++VNNAGIG +G F DT E Sbjct 361 SRLIGARA--AWAEAVDVSDEQAMEKLAARVAAEYGVVDVLVNNAGIGLSGSFFDTTPED 418 Query 425 FDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMF 484 + +VL VNL GV++GCR FG+++ ERG GGHIVN +S AA+ P + L AY TSKAA M Sbjct 419 WKKVLDVNLWGVIHGCRLFGRQMAERGQGGHIVNTASAAAFQPSRVLPAYGTSKAAVLML 478 Query 485 SDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYG 544 S+CLRAEL G+G+T ICPG+++TNI +T H G D E+ R+ + +++ R+Y Sbjct 479 SECLRAELADRGIGVTAICPGLVNTNITSTA--HFAGVDAEEEKRRQQRTARLYGARNYP 536 Query 545 PDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLR 590 P+KVADA++ AV + + + PV PEA + +SR P+ LR AR++ Sbjct 537 PEKVADAVLEAVVRNRAVVPVTPEARGAHLMSRFAPRMLRRLARVK 582 >gi|83749781|ref|ZP_00946755.1| Short chain dehydrogenase [Ralstonia solanacearum UW551] gi|207743227|ref|YP_002259619.1| alpha/beta hydrolase fold;short-chain dehydrogenase/reductase sdr; protein [Ralstonia solanacearum IPO1609] gi|83723538|gb|EAP70742.1| Short chain dehydrogenase [Ralstonia solanacearum UW551] gi|206594624|emb|CAQ61551.1| putative alpha/beta hydrolase fold;short-chain dehydrogenase/reductase sdr; protein [Ralstonia solanacearum IPO1609] Length=599 Score = 415 bits (1066), Expect = 1e-113, Method: Compositional matrix adjust. Identities = 240/579 (42%), Positives = 336/579 (59%), Gaps = 10/579 (1%) Query 11 VDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSS 70 V S D V +AV G+P PTVVLVHG+PD+ +W + LLA + ++ YD RG GRSS Sbjct 26 VQSGD-VTLAVKTWGDPARPTVVLVHGYPDNSEVWHTMARLLAPDYYVIAYDVRGAGRSS 84 Query 71 VPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTS 130 PK + YT DDF AVI LSP +PVH++AHDWGS+ W ++ R+AS+TS Sbjct 85 APKGLRHYTFVRLTDDFIAVIDALSPTKPVHLVAHDWGSIQGWTFVTEERLRGRIASYTS 144 Query 131 VSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAA 190 SGP DH+ +++ L RP P + + + Q +R Y+ LF +PV+ L R+ L A Sbjct 145 CSGPCLDHVGHWMRTRLLRP-TPASLGKLLGQLVRSWYVLLFHLPVLPELSWRLWLGRAW 203 Query 191 VRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVN 250 ++ + I T D H V Y AN+ RS + R+ A PVQ+IV Sbjct 204 P--GLLRRVEKTAIAPRATQTADGLHGVSLYRANFIRSLFAPRKRYA----HAPVQVIVP 257 Query 251 SQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRAL 310 + D YV P + +RWVPR WRR+I A H+ P++HP+ MA + + A+G+ S AL Sbjct 258 TLDKYVSPALSEDLSRWVPRYWRREIVARHWLPVTHPERMAEMARELIEHAEGRPESEAL 317 Query 311 LRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAA 370 RA++G R L +TGAGSGIGR AL FA +GA IV DI + TA + Sbjct 318 RRARMGGVRKPLAGKLAVITGAGSGIGRCAALEFAGQGASIVAVDIRGDDAERTATLVRL 377 Query 371 RGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLA 430 GG A+ DV AE + A A+ V AE G DIVVNNAGIG AG +DT + RVL Sbjct 378 TGGRAWARTADVGSAEQMTALADWVGAELGGADIVVNNAGIGMAGGIVDTTERDWQRVLH 437 Query 431 VNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRA 490 VNL GV++G R F +++V RG GGHIVN +S AA++P + L+ Y T+KAA M S+C+R Sbjct 438 VNLWGVIHGARLFARQMVARGQGGHIVNTASAAAFSPSRDLATYATTKAAVLMLSECMRG 497 Query 491 ELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVAD 550 EL G+G++ ICPG +T I+A+T + GT E + R + +++ R P+ VA Sbjct 498 ELAGQGIGVSAICPGFAETGIMASTVY--AGTTEAQQAALRKRATQLYQRRGLKPEAVAR 555 Query 551 AIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 A++ AV + +PI + EA+++ +SR P R AR+ Sbjct 556 AMLRAVLRNQPIVSIGIEAHSMRLVSRYAPWLGRLMARV 594 >gi|334196045|gb|AEG69230.1| 3-ketoacyl-(acyl-carrier-protein) reductase [Ralstonia solanacearum Po82] Length=599 Score = 415 bits (1066), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 242/582 (42%), Positives = 336/582 (58%), Gaps = 10/582 (1%) Query 8 SRLVDSPDGVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVG 67 R V S D V +AV G+P TVVLVHG+PD+ +W + LL + ++ YD RG G Sbjct 23 ERTVQSGD-VTLAVKTWGDPARSTVVLVHGYPDNSEVWHTMARLLTPDYYVIAYDVRGAG 81 Query 68 RSSVPKPISAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVAS 127 RSS PK + YT A DDF AVI LSP VH++AHDWGS+ W ++ R+AS Sbjct 82 RSSAPKGLRHYTFARLTDDFIAVIDALSPTRLVHLVAHDWGSIQGWAFVTEERLRGRIAS 141 Query 128 FTSVSGPSQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALS 187 +TS SGP DH+ +++ L RP P + + Q +R Y+ LF +PV+ L R+ L Sbjct 142 YTSCSGPCLDHVGHWMRTRLLRP-TPALLGKLLGQLVRSWYVLLFHLPVLPELSWRLWLG 200 Query 188 SAAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQL 247 A ++ + I T A D H V Y AN+ RS + R+ A PVQ+ Sbjct 201 RAWP--GLLRRVEKTAIAPRATQAADGLHGVSLYRANFIRSLVAPRKRYA----HAPVQV 254 Query 248 IVNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPS 307 IV + D YV P + +RWVPR WRR+I A H+ P++HP+ MA + + A+G+ S Sbjct 255 IVPTLDKYVSPALSEDLSRWVPRYWRREIVARHWLPVTHPERMAEMARELIEHAEGRPES 314 Query 308 RALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAE 367 AL RA++G R L +TGAGSGIGR AL FA +GA IV DI + TA Sbjct 315 EALRRARMGGVRKPLAGKLAVITGAGSGIGRCAALEFAGQGASIVAVDIRGDDAERTATL 374 Query 368 IAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDR 427 + GG A+ DV AE + A A+ V AE G DIVVNNAGIG AG +DT + R Sbjct 375 VRLAGGRAWARTADVGSAEQMTALADWVGAELGGADIVVNNAGIGMAGGIVDTTERDWQR 434 Query 428 VLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDC 487 VL VNL GV++G R F +++V RG GGHIVN +S AA++P + L+AY T+KAA M S+C Sbjct 435 VLHVNLWGVIHGARLFARQMVARGQGGHIVNTASAAAFSPSRDLAAYATTKAAVLMLSEC 494 Query 488 LRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDK 547 +R EL G+G++ ICPG +T I+A+T + GT E + R ++ +++ R P+ Sbjct 495 MRGELAGQGIGVSAICPGFAETGIMASTVY--TGTTEAQQAALRKRVTQLYQRRGLKPEA 552 Query 548 VADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 VA A++ AV + +PI + EA+A+ +SR P R AR+ Sbjct 553 VARAMLRAVLRNQPIVSIGIEAHAMRLVSRYAPWLGRLMARV 594 >gi|291438586|ref|ZP_06577976.1| short chain dehydrogenase [Streptomyces ghanaensis ATCC 14672] gi|291341481|gb|EFE68437.1| short chain dehydrogenase [Streptomyces ghanaensis ATCC 14672] Length=585 Score = 414 bits (1063), Expect = 3e-113, Method: Compositional matrix adjust. Identities = 249/577 (44%), Positives = 332/577 (58%), Gaps = 12/577 (2%) Query 16 GVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPI 75 G+ + V G+PD PTVVLVHG+PDS +W V P LAE F +V YD RG GRS+ P+P+ Sbjct 16 GIELCVAELGDPDRPTVVLVHGYPDSKEVWSEVAPRLAEHFHVVAYDVRGHGRSTAPRPL 75 Query 76 -SAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGP 134 +T+ DDF AV +SP PVH++ HDWGSV WE++ R+ASFTS+SGP Sbjct 76 RGGFTLEKLTDDFLAVADAVSPDRPVHLVGHDWGSVQSWEFVTVARTEGRIASFTSMSGP 135 Query 135 SQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRN 194 S DHL +++ L RP PR + + Q R Y+ L PV+ L R L R Sbjct 136 SLDHLGHWIGRRLGRP-TPRRIGQLLGQGARSWYVYLLHTPVLPELAWRGPLGRHWPRLL 194 Query 195 MVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQDP 254 + + + +L DAAH Y N S R A PVQLI +D Sbjct 195 ERAEKVPGGDYPTPSLPSDAAHGAWLYRDNVRPRLRSPR---ADAYAHAPVQLITPLEDV 251 Query 255 YVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLRAQ 314 ++ +D+ RW PR RR + A H+ P + P ++A + +F + +P A Sbjct 252 FLSERLHDELERWAPRSIRRTLPAKHWVPRTRPDLLAHWITEFVTSVEDGRPKAA----A 307 Query 315 VGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDID-EATVKDTAAEIAARGG 373 GR FG LV VTGAGSGIGR TALAFA GA ++ D D A + Sbjct 308 PGRYADRFGGQLVLVTGAGSGIGRATALAFADAGARVLAVDRDGRAAARTAEEARRRGAA 367 Query 374 IAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNL 433 A+ DVSD +A+E AERV+AEHGV D++VNNAGIG G F DT +++ VL VNL Sbjct 368 AAWARTADVSDEQAMERLAERVTAEHGVVDVLVNNAGIGLGGSFFDTTPKEWKEVLDVNL 427 Query 434 GGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELD 493 GV++GCR FG+R+ ERG GGHIVNV+S AA+ P +SL AY TSKAA M S+CLRAEL Sbjct 428 WGVIHGCRLFGRRMAERGQGGHIVNVASAAAFQPSRSLPAYGTSKAAVLMLSECLRAELA 487 Query 494 AAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIV 553 G+G+T +CPG ++T I +T F G D E+ R + +++ LR Y P+KVA AI+ Sbjct 488 GRGIGVTAVCPGFVNTAIASTARF--AGADAEEERRLRKRAARLYGLRDYPPEKVAAAIL 545 Query 554 SAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLR 590 AV + + + PV PEA Y +SR +P ALR AR++ Sbjct 546 RAVVRNEAVVPVTPEARTAYALSRWMPGALRRIARVK 582 >gi|289770441|ref|ZP_06529819.1| short chain dehydrogenase [Streptomyces lividans TK24] gi|289700640|gb|EFD68069.1| short chain dehydrogenase [Streptomyces lividans TK24] Length=585 Score = 413 bits (1062), Expect = 4e-113, Method: Compositional matrix adjust. Identities = 250/586 (43%), Positives = 332/586 (57%), Gaps = 30/586 (5%) Query 16 GVRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPI 75 GV + V G+P PTVVLVHG+PDS +W V LA RF +V YD RG GRSS P P+ Sbjct 16 GVELCVAELGDPRRPTVVLVHGYPDSKEVWSEVAARLAGRFHVVLYDVRGHGRSSAPSPL 75 Query 76 -SAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGP 134 +T+ DDF AV +SP PVH++ HDWGSV WE++ R+ASFTS+SGP Sbjct 76 RGGFTLEKLTDDFLAVADAVSPDRPVHLVGHDWGSVQSWEFVTVKRTEGRIASFTSMSGP 135 Query 135 SQDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSS------ 188 S DH +++ LRRP PR + + Q + Y+ L PV+ L R L Sbjct 136 SLDHFGHWINKRLRRP-TPRRVGQLLGQGAKSWYVYLLHTPVLPELAWRGPLGKRWPGIL 194 Query 189 AAVRRNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLI 248 V + GD P + +L DAAH Y N RR R PVQLI Sbjct 195 ERVEKVPGGDYP------TASLPSDAAHGAWLYRDNVRPRL---RRPREDAYAHAPVQLI 245 Query 249 VNSQDPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFAD-LADGKQPS 307 D ++ YD W PRL RR + A H+ P + P +A + +F DG+ + Sbjct 246 TPLGDAFLSERLYDGLELWAPRLTRRTLPAKHWVPRTRPDRLADWITEFVTATEDGRSET 305 Query 308 RALLRAQVGRPRGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAE 367 A G+ FG LV VTGAGSGIGR TA AFA GA +V D D TA Sbjct 306 -----AANGKYADRFGGQLVLVTGAGSGIGRATAFAFAEAGARVVAVDRDAEAAARTAEL 360 Query 368 ---IAARGGIAYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQ 424 I AR A+ +DVSD +A+E A RV+AE+GV D++VNNAGIG +G F DT E Sbjct 361 SRLIGARA--AWAEAVDVSDEQAMEKLAARVAAEYGVVDVLVNNAGIGLSGSFFDTTPED 418 Query 425 FDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMF 484 + +VL VNL GV++GCR FG+++ ERG GGHIVN +S AA+ P + L AY TSKAA M Sbjct 419 WKKVLDVNLWGVIHGCRLFGRQMAERGQGGHIVNTASAAAFQPSRVLPAYGTSKAAVLML 478 Query 485 SDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKIDGRRGQIDKMFALRSYG 544 S+CLR EL G+G+T ICPG+++TNI +T H G D E+ R+ + +++ R+Y Sbjct 479 SECLRTELADRGIGVTAICPGLVNTNITSTA--HFAGVDAEEEKRRQQRTARLYGARNYP 536 Query 545 PDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTARLR 590 P+KVADA++ AV + + + PV PEA + +SR P+ LR AR++ Sbjct 537 PEKVADAVLEAVVRNRAVVPVTPEARGAHLMSRFAPRMLRRLARVK 582 >gi|337767190|emb|CCB75901.1| putative oxidoreductase ephD [Streptomyces cattleya NRRL 8057] Length=624 Score = 411 bits (1057), Expect = 2e-112, Method: Compositional matrix adjust. Identities = 257/602 (43%), Positives = 337/602 (56%), Gaps = 38/602 (6%) Query 17 VRIAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPI- 75 V ++V G+P PTVVLVHG+PD +W V LA RF +V YD RG G SS P+P+ Sbjct 28 VDLSVTEYGDPARPTVVLVHGYPDCKEVWQPVADRLAGRFHVVLYDVRGHGASSAPEPLR 87 Query 76 SAYTMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPS 135 + + DDF AV +SP PVH++ HDWGSV WE+ R+ASFTSVSGPS Sbjct 88 GGFRLEKLTDDFLAVADAVSPDRPVHLVGHDWGSVQGWEFATVRRTEGRIASFTSVSGPS 147 Query 136 QDHLVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSS---AAVR 192 DH +++ + RP PR + + Q R Y+ PV+ L R L A + Sbjct 148 LDHFGHWIKERVARP-TPRRTAQLLGQGARSWYVYALHTPVLPELAWRGVLGRRWPAMLA 206 Query 193 RNMVGDIPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQ 252 R V +P D + + +L +DAAH Y N RR R VPVQLI S Sbjct 207 R--VERLPEDAGYPTASLRQDAAHGAWLYRDNVRERL---RRPRPDAYAHVPVQLITPSG 261 Query 253 DPYVRPYGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLR 312 D ++ YD RW P L RR + A H+ P + P +AA + +FAD +G A Sbjct 262 DLFLSERLYDDLERWAPGLRRRTLSAKHWVPRTRPDQLAAWIAEFADAHEGTSTGAATET 321 Query 313 A-------QVGRPRGY----------------FGDTLVSVTGAGSGIGRETALAFAREGA 349 A + GRP F LV VTGAGSGIGR TA AFA GA Sbjct 322 APAGSGAGRTGRPGARSRTSAAERLTARAAERFAGQLVLVTGAGSGIGRATAYAFAEAGA 381 Query 350 EIVISDIDEATVKDTAAEIAARGGI--AYPYVLDVSDAEAVEAFAERVSAEHGVPDIVVN 407 IV D D TA E++ G A+ V DVSD A+E A+RV+ HGV D++VN Sbjct 382 RIVAVDRDPEGAARTA-ELSRLLGAPEAWAEVTDVSDERAMEKLADRVTDSHGVVDVLVN 440 Query 408 NAGIGQAGRFLDTPAEQFDRVLAVNLGGVVNGCRAFGQRLVERGTGGHIVNVSSMAAYAP 467 NAGIG AG FLDT A+ + +VL VNL GV++GCR FGQR+ ERG GGHIVN +S AAY P Sbjct 441 NAGIGLAGSFLDTTADDWRKVLDVNLWGVLHGCRLFGQRMTERGQGGHIVNTASAAAYLP 500 Query 468 LQSLSAYCTSKAATYMFSDCLRAELDAAGVGLTTICPGVIDTNIVATTGFHAPGTDEEKI 527 ++L AY TSKAA M S+CLRAEL G+G+T +CPG++DTNI ATT F G +++ Sbjct 501 SRTLPAYSTSKAAVLMLSECLRAELAPHGIGVTAVCPGLVDTNITATTRF--TGVSDQEQ 558 Query 528 DGRRGQIDKMFALRSYGPDKVADAIVSAVKKKKPIRPVAPEAYALYGISRVLPQALRSTA 587 + R + +++ +R+Y P+KVA A++ V + PV PEA +SR+ P A+R+ A Sbjct 559 ERMRAKSSRLYRIRAYPPEKVAAALLRGVLDNTAVVPVTPEARGARLLSRLSPAAIRALA 618 Query 588 RL 589 RL Sbjct 619 RL 620 >gi|172063922|ref|YP_001811573.1| short chain dehydrogenase [Burkholderia ambifaria MC40-6] gi|171996439|gb|ACB67357.1| short-chain dehydrogenase/reductase SDR [Burkholderia ambifaria MC40-6] Length=595 Score = 408 bits (1048), Expect = 2e-111, Method: Compositional matrix adjust. Identities = 233/572 (41%), Positives = 328/572 (58%), Gaps = 11/572 (1%) Query 19 IAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPISAY 78 +AV G+P VVLVHG+PD +W V PLLA + ++ YD RG G S VPK + Y Sbjct 29 LAVRTWGDPPRSPVVLVHGYPDDSSVWQHVAPLLARKHYVIAYDVRGAGLSGVPKRTADY 88 Query 79 TMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQDH 138 +A DDF AVI L PG VH++AHDWGS+ WE++ P + R+AS+TS SGP DH Sbjct 89 HLAKLTDDFIAVIDTLCPGRAVHLIAHDWGSIQGWEFVTDPRLAGRIASYTSCSGPCLDH 148 Query 139 LVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNMVGD 198 + ++ + RP P + + Q +R Y+ +F +P + L R+ L A ++ Sbjct 149 VGFWLRERVLRP-TPASLAKLGGQLVRSWYVYVFHLPFIPELSWRLWLGRA--WPGLLRR 205 Query 199 IPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQDPYVRP 258 + I T A D AH V+ Y AN+ R + R A PVQ IV D YV P Sbjct 206 VEKTPIAPRATQADDGAHGVRLYRANFIRCLFAPRERYA----HAPVQTIVPLGDKYVSP 261 Query 259 YGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLRAQVGRP 318 + +RWVP+ +RR++ AGH+ P++ P A D + + AL A+ Sbjct 262 ALSENLSRWVPQYYRREVAAGHWLPLADPARFAELAEQLIDAVESGEEPPALANARRRAT 321 Query 319 RGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYPY 378 G F +V VTGAGSGIGR ALAFAREGA +V DI+ A+ + TA + G AY Sbjct 322 SGRFSGKVVVVTGAGSGIGRCAALAFAREGATVVACDIELASAERTALLLGLIGAQAYAK 381 Query 379 VLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVN 438 +DV A+ +EA A V +E G D+++NNAGIG AG LDT A ++R+L VNL GV++ Sbjct 382 CVDVGSADEMEALATWVGSELGGADVLINNAGIGMAGGILDTTAHHWERILHVNLWGVIH 441 Query 439 GCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAGVG 498 G R F +++ RGTGGHIVN +S AA+ P + L AY T+KAA M S+C+RAEL G+G Sbjct 442 GSRLFARQMAARGTGGHIVNTASAAAFGPSRDLPAYATTKAAVLMLSECMRAELAEKGIG 501 Query 499 LTTICPGVIDTNIVATTGFH-APGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIVSAVK 557 +T +CPG +T I+A+T + A DE ++ R + K++ +R P+ VA AIV V Sbjct 502 VTAVCPGFAETGIMASTQYAGANAQDEARL---RKRATKLYQMRGLKPETVAQAIVDGVL 558 Query 558 KKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 + +P+ V EA+AL + R +P R AR+ Sbjct 559 RNRPVVAVGAEAHALRVVGRFMPWLGRMLARI 590 >gi|115359139|ref|YP_776277.1| short chain dehydrogenase [Burkholderia ambifaria AMMD] gi|115284427|gb|ABI89943.1| short-chain dehydrogenase/reductase SDR [Burkholderia ambifaria AMMD] Length=618 Score = 407 bits (1045), Expect = 4e-111, Method: Compositional matrix adjust. Identities = 233/572 (41%), Positives = 326/572 (57%), Gaps = 11/572 (1%) Query 19 IAVYHEGNPDGPTVVLVHGFPDSHVLWDGVVPLLAERFRIVRYDNRGVGRSSVPKPISAY 78 +AV G+P VVLVHG+PD +W V PLLA + ++ YD RG G S VPK + Y Sbjct 52 LAVRTWGDPARSPVVLVHGYPDDSSVWQHVAPLLARKHYVIAYDVRGAGLSGVPKRTADY 111 Query 79 TMAHFADDFDAVIGELSPGEPVHVLAHDWGSVGVWEYLRRPGASDRVASFTSVSGPSQDH 138 +A DDF AVI L PG VH++AHDWG++ WE++ P + R+AS+TS SGP DH Sbjct 112 HLAKLTDDFIAVIDTLCPGRAVHLIAHDWGAIQGWEFVTDPRLAGRIASYTSCSGPCLDH 171 Query 139 LVNYVYGGLRRPWRPRTFLRAISQTLRLSYMALFSVPVVAPLLLRVALSSAAVRRNMVGD 198 + ++ + RP P + + Q +R Y+ LF +P + L R+ L A R ++ Sbjct 172 VGFWLRERVLRP-TPASLAKLGGQLVRSWYVVLFHLPFIPELSWRLWLGRAWPR--LLRR 228 Query 199 IPVDQIHHSETLARDAAHSVKTYPANYFRSFSSSRRGRAIPIVDVPVQLIVNSQDPYVRP 258 I T A D AH V+ Y AN+ R + R A PVQ IV D YV P Sbjct 229 IEKTPAAPRATQADDGAHGVRLYRANFIRCLFAPRERYA----HAPVQTIVPLGDKYVSP 284 Query 259 YGYDQTARWVPRLWRRDIKAGHFSPMSHPQVMAAAVHDFADLADGKQPSRALLRAQVGRP 318 + +RWVP+ +RR++ AGH+ P++ P A D + AL A+ Sbjct 285 ALSENLSRWVPQYYRREVAAGHWLPLADPARFAGLAEQLIDAVESGDEPPALANARRRAT 344 Query 319 RGYFGDTLVSVTGAGSGIGRETALAFAREGAEIVISDIDEATVKDTAAEIAARGGIAYPY 378 G F +V VTGAGSGIGR ALAFAREGA +V DI+ A+ + TA + G + Sbjct 345 SGRFSGKVVVVTGAGSGIGRCAALAFAREGATVVACDIELASAERTALLLGLIGAQTHAK 404 Query 379 VLDVSDAEAVEAFAERVSAEHGVPDIVVNNAGIGQAGRFLDTPAEQFDRVLAVNLGGVVN 438 +DV A+ +EA A V +E G D+V+NNAGIG AG LDT A ++R+L VNL GV++ Sbjct 405 CVDVGSADEMEALATWVGSELGGADVVINNAGIGMAGGILDTTAHHWERILHVNLWGVIH 464 Query 439 GCRAFGQRLVERGTGGHIVNVSSMAAYAPLQSLSAYCTSKAATYMFSDCLRAELDAAGVG 498 G R F Q++ RGTGGHIVN +S AA+ P + L AY T+KAA M S+C+RAEL G+G Sbjct 465 GSRLFAQQMAARGTGGHIVNTASAAAFGPSRDLPAYATTKAAVLMLSECMRAELAEKGIG 524 Query 499 LTTICPGVIDTNIVATTGFH-APGTDEEKIDGRRGQIDKMFALRSYGPDKVADAIVSAVK 557 +T +CPG +T I+A+T + A DE ++ R + K++ +R P+ VA A+V V Sbjct 525 VTAVCPGFAETGIMASTQYAGANAQDEARL---RKRATKLYQMRGLKPETVAQAMVDGVL 581 Query 558 KKKPIRPVAPEAYALYGISRVLPQALRSTARL 589 + +P+ V EA+AL + R +P R AR+ Sbjct 582 RNRPVVAVGAEAHALRIVGRFMPWLGRMLARI 613 Lambda K H 0.321 0.136 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1346175490266 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40