BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2218 Length=311 Score E Sequences producing significant alignments: (Bits) Value gi|15609355|ref|NP_216734.1| lipoyl synthase [Mycobacterium tube... 630 1e-178 gi|339295132|gb|AEJ47243.1| lipoyl synthase [Mycobacterium tuber... 628 4e-178 gi|306808528|ref|ZP_07445196.1| lipoate biosynthesis protein A l... 628 4e-178 gi|342857223|ref|ZP_08713879.1| lipoyl synthase [Mycobacterium c... 578 5e-163 gi|296166095|ref|ZP_06848540.1| lipoic acid synthetase [Mycobact... 574 7e-162 gi|254820908|ref|ZP_05225909.1| lipoyl synthase [Mycobacterium i... 570 9e-161 gi|254774941|ref|ZP_05216457.1| lipoyl synthase [Mycobacterium a... 568 4e-160 gi|118464691|ref|YP_881474.1| lipoyl synthase [Mycobacterium avi... 568 4e-160 gi|41408057|ref|NP_960893.1| lipoyl synthase [Mycobacterium aviu... 568 5e-160 gi|240168288|ref|ZP_04746947.1| lipoyl synthase [Mycobacterium k... 563 2e-158 gi|15827383|ref|NP_301646.1| lipoyl synthase [Mycobacterium lepr... 558 3e-157 gi|118617035|ref|YP_905367.1| lipoyl synthase [Mycobacterium ulc... 551 5e-155 gi|108800282|ref|YP_640479.1| lipoyl synthase [Mycobacterium sp.... 548 6e-154 gi|118472901|ref|YP_888563.1| lipoyl synthase [Mycobacterium sme... 539 2e-151 gi|120401929|ref|YP_951758.1| lipoyl synthase [Mycobacterium van... 532 3e-149 gi|120404553|ref|YP_954382.1| lipoyl synthase [Mycobacterium van... 528 6e-148 gi|145223519|ref|YP_001134197.1| lipoyl synthase [Mycobacterium ... 527 1e-147 gi|315443865|ref|YP_004076744.1| lipoate synthase [Mycobacterium... 526 1e-147 gi|340525485|gb|AEK40690.1| lipoyl synthase [Amycolatopsis medit... 523 2e-146 gi|325677046|ref|ZP_08156717.1| lipoic acid synthetase [Rhodococ... 522 3e-146 gi|312140208|ref|YP_004007544.1| lipoyl synthase lipa [Rhodococc... 522 3e-146 gi|111018167|ref|YP_701139.1| lipoyl synthase [Rhodococcus josti... 521 4e-146 gi|300783739|ref|YP_003764030.1| lipoic acid synthetase [Amycola... 521 4e-146 gi|226360295|ref|YP_002778073.1| lipoyl synthase [Rhodococcus op... 521 7e-146 gi|226307107|ref|YP_002767067.1| lipoyl synthase [Rhodococcus er... 516 2e-144 gi|54023654|ref|YP_117896.1| lipoyl synthase [Nocardia farcinica... 516 2e-144 gi|169629029|ref|YP_001702678.1| lipoyl synthase [Mycobacterium ... 516 2e-144 gi|333918930|ref|YP_004492511.1| lipoyl synthase [Amycolicicoccu... 516 3e-144 gi|326382496|ref|ZP_08204187.1| lipoyl synthase [Gordonia neofel... 513 2e-143 gi|229780997|ref|YP_001103870.2| lipoyl synthase [Saccharopolysp... 513 2e-143 gi|343924148|ref|ZP_08763711.1| lipoyl synthase [Gordonia alkani... 512 2e-143 gi|229820350|ref|YP_002881876.1| lipoyl synthase [Beutenbergia c... 510 1e-142 gi|302525064|ref|ZP_07277406.1| lipoyl synthase [Streptomyces sp... 509 2e-142 gi|302525317|ref|ZP_07277659.1| lipoyl synthase [Streptomyces sp... 509 3e-142 gi|300784074|ref|YP_003764365.1| lipoic acid synthetase [Amycola... 508 3e-142 gi|331698337|ref|YP_004334576.1| Lipoyl synthase [Pseudonocardia... 508 4e-142 gi|302546040|ref|ZP_07298382.1| lipoyl synthase [Streptomyces hy... 506 1e-141 gi|256375478|ref|YP_003099138.1| lipoyl synthase [Actinosynnema ... 506 2e-141 gi|257055093|ref|YP_003132925.1| lipoyl synthase [Saccharomonosp... 505 4e-141 gi|262202969|ref|YP_003274177.1| lipoic acid synthetase [Gordoni... 504 6e-141 gi|326330114|ref|ZP_08196425.1| lipoyl synthase [Nocardioidaceae... 504 8e-141 gi|334337346|ref|YP_004542498.1| Lipoyl synthase [Isoptericola v... 503 1e-140 gi|296139233|ref|YP_003646476.1| lipoic acid synthetase [Tsukamu... 502 4e-140 gi|284030610|ref|YP_003380541.1| lipoic acid synthetase [Kribbel... 501 7e-140 gi|297161185|gb|ADI10897.1| lipoyl synthase [Streptomyces bingch... 500 9e-140 gi|133910832|emb|CAM00945.1| putative lipoic acid synthetase [Sa... 499 2e-139 gi|312195619|ref|YP_004015680.1| lipoic acid synthetase [Frankia... 498 5e-139 gi|269956823|ref|YP_003326612.1| lipoic acid synthetase [Xylanim... 498 5e-139 gi|152967232|ref|YP_001363016.1| lipoyl synthase [Kineococcus ra... 498 5e-139 gi|72161395|ref|YP_289052.1| lipoyl synthase [Thermobifida fusca... 497 8e-139 >gi|15609355|ref|NP_216734.1| lipoyl synthase [Mycobacterium tuberculosis H37Rv] gi|15841709|ref|NP_336746.1| lipoyl synthase [Mycobacterium tuberculosis CDC1551] gi|31793397|ref|NP_855890.1| lipoyl synthase [Mycobacterium bovis AF2122/97] 82 more sequence titles Length=311 Score = 630 bits (1624), Expect = 1e-178, Method: Compositional matrix adjust. Identities = 311/311 (100%), Positives = 311/311 (100%), Gaps = 0/311 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC Sbjct 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG Sbjct 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE Sbjct 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 Query 301 QARNSRALASR 311 QARNSRALASR Sbjct 301 QARNSRALASR 311 >gi|339295132|gb|AEJ47243.1| lipoyl synthase [Mycobacterium tuberculosis CCDC5079] Length=311 Score = 628 bits (1619), Expect = 4e-178, Method: Compositional matrix adjust. Identities = 310/311 (99%), Positives = 311/311 (100%), Gaps = 0/311 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC Sbjct 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRT+GLRYATV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTVGLRYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG Sbjct 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE Sbjct 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 Query 301 QARNSRALASR 311 QARNSRALASR Sbjct 301 QARNSRALASR 311 >gi|306808528|ref|ZP_07445196.1| lipoate biosynthesis protein A lipA [Mycobacterium tuberculosis SUMu007] gi|308345027|gb|EFP33878.1| lipoate biosynthesis protein A lipA [Mycobacterium tuberculosis SUMu007] Length=311 Score = 628 bits (1619), Expect = 4e-178, Method: Compositional matrix adjust. Identities = 310/311 (99%), Positives = 310/311 (99%), Gaps = 0/311 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC Sbjct 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFC IDTGKPAELDRDEPRRVADSVRTMGLRYATV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCHIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG Sbjct 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE Sbjct 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 Query 301 QARNSRALASR 311 QARNSRALASR Sbjct 301 QARNSRALASR 311 >gi|342857223|ref|ZP_08713879.1| lipoyl synthase [Mycobacterium colombiense CECT 3035] gi|342134556|gb|EGT87722.1| lipoyl synthase [Mycobacterium colombiense CECT 3035] Length=307 Score = 578 bits (1489), Expect = 5e-163, Method: Compositional matrix adjust. Identities = 282/307 (92%), Positives = 293/307 (96%), Gaps = 0/307 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGR+LLRLEVRNA+TPIERKPPWI+ RAR+GPEYT+LK+LVRREGLHTVCEEAGC Sbjct 1 MTVAPEGRKLLRLEVRNAETPIERKPPWIRVRARMGPEYTQLKSLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSV TMGLRYATV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVHTMGLRYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVRAIKELNPSTGVELLIPDFNGEP RLAEVFES PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRAIKELNPSTGVELLIPDFNGEPARLAEVFESRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAFTYRRSL VLTAARD GLVTKSNLILG+GET DEVRTAL DLRDAG Sbjct 181 VETVPRIFKRIRPAFTYRRSLDVLTAARDFGLVTKSNLILGMGETPDEVRTALADLRDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPSARHHPVERWVKPEEFV+FA+ AE LGFAGVLAGPLVRSSYRAGRLYE Sbjct 241 CDIITITQYLRPSARHHPVERWVKPEEFVEFAQHAEQLGFAGVLAGPLVRSSYRAGRLYE 300 Query 301 QARNSRA 307 QA SRA Sbjct 301 QAARSRA 307 >gi|296166095|ref|ZP_06848540.1| lipoic acid synthetase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898504|gb|EFG78065.1| lipoic acid synthetase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=307 Score = 574 bits (1479), Expect = 7e-162, Method: Compositional matrix adjust. Identities = 279/307 (91%), Positives = 292/307 (96%), Gaps = 0/307 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGR+LLRLEVRNAQTPIERKPPWIK RAR+GPEYT+LK LVRREGLHTVCEEAGC Sbjct 1 MTVAPEGRKLLRLEVRNAQTPIERKPPWIKVRARMGPEYTQLKGLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPA LDRDEPRRVADSVRTMGLRYAT+ Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAALDRDEPRRVADSVRTMGLRYATI 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVRAIKELNP+TGVELLIPDFNGEP RLAEVFES PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRAIKELNPATGVELLIPDFNGEPARLAEVFESRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKR+RPAF+Y+RSL V+TAARDAGLVTKSNLILGLGET DEVRTAL DLR AG Sbjct 181 VETVPRIFKRVRPAFSYQRSLDVITAARDAGLVTKSNLILGLGETPDEVRTALADLRGAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDIVTITQYLRPS RHHPVERWV+PEEFV+FAR AEGLGFAGVLAGPLVRSSYRAGRLYE Sbjct 241 CDIVTITQYLRPSTRHHPVERWVRPEEFVEFARHAEGLGFAGVLAGPLVRSSYRAGRLYE 300 Query 301 QARNSRA 307 QA +RA Sbjct 301 QAARTRA 307 >gi|254820908|ref|ZP_05225909.1| lipoyl synthase [Mycobacterium intracellulare ATCC 13950] Length=313 Score = 570 bits (1469), Expect = 9e-161, Method: Compositional matrix adjust. Identities = 276/301 (92%), Positives = 290/301 (97%), Gaps = 0/301 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGR+LLRLEVRNA+TPIERKPPWI+ RA++GPEYTELK+LVRREGLHTVCEEAGC Sbjct 1 MTVAPEGRKLLRLEVRNAETPIERKPPWIRVRAKMGPEYTELKSLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVRAIKELNPSTGVELLIPDFNGEP RLAEVFES PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRAIKELNPSTGVELLIPDFNGEPARLAEVFESRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAFTY+RSL VLTAARDAGLVTKSNLILGLGET DEVRTAL DLR AG Sbjct 181 VETVPRIFKRIRPAFTYQRSLDVLTAARDAGLVTKSNLILGLGETPDEVRTALADLRHAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPSARHHPVERWVKPEEFV+FA+ AE LGF+GVL+GPLVRSSYRAGRLY+ Sbjct 241 CDIITITQYLRPSARHHPVERWVKPEEFVEFAQHAEQLGFSGVLSGPLVRSSYRAGRLYQ 300 Query 301 Q 301 Q Sbjct 301 Q 301 >gi|254774941|ref|ZP_05216457.1| lipoyl synthase [Mycobacterium avium subsp. avium ATCC 25291] Length=307 Score = 568 bits (1464), Expect = 4e-160, Method: Compositional matrix adjust. Identities = 279/307 (91%), Positives = 291/307 (95%), Gaps = 0/307 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGR+LLRLEVRNA+TPIERKPPWI+ RAR+GPEYTELK+LVRREGLHTVCEEAGC Sbjct 1 MTVAPEGRKLLRLEVRNAETPIERKPPWIRVRARMGPEYTELKSLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVRAIKELNPSTGVELLIPDFNG P RLAEVF S PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRAIKELNPSTGVELLIPDFNGRPDRLAEVFGSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAFTYRRSL VLTAAR+AGLVTKSNLILGLGET DEVRTAL DLR AG Sbjct 181 VETVPRIFKRIRPAFTYRRSLDVLTAAREAGLVTKSNLILGLGETPDEVRTALADLRGAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CD++TITQYLRPSARHHPVERWVKPEEFV+FAR AE LGF+GVLAGPLVRSSYRAGRLY Sbjct 241 CDLITITQYLRPSARHHPVERWVKPEEFVEFARHAEELGFSGVLAGPLVRSSYRAGRLYR 300 Query 301 QARNSRA 307 QA +RA Sbjct 301 QAARARA 307 >gi|118464691|ref|YP_881474.1| lipoyl synthase [Mycobacterium avium 104] gi|166230422|sp|A0QEY6.1|LIPA_MYCA1 RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|118165978|gb|ABK66875.1| lipoic acid synthetase [Mycobacterium avium 104] Length=307 Score = 568 bits (1464), Expect = 4e-160, Method: Compositional matrix adjust. Identities = 280/307 (92%), Positives = 290/307 (95%), Gaps = 0/307 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGR+LLRLEVRNA TPIERKPPWI+ RAR+GPEYTELK+LVRREGLHTVCEEAGC Sbjct 1 MTVAPEGRKLLRLEVRNADTPIERKPPWIRVRARMGPEYTELKSLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVRAIKELNPSTGVELLIPDFNG P RLAEVF S PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRAIKELNPSTGVELLIPDFNGRPDRLAEVFGSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAFTYRRSL VLTAAR+AGLVTKSNLILGLGET DEVRTAL DLR AG Sbjct 181 VETVPRIFKRIRPAFTYRRSLDVLTAAREAGLVTKSNLILGLGETPDEVRTALADLRGAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPSARHHPVERWVKPEEFV+FAR AE LGF+GVLAGPLVRSSYRAGRLY Sbjct 241 CDIITITQYLRPSARHHPVERWVKPEEFVEFARHAEELGFSGVLAGPLVRSSYRAGRLYR 300 Query 301 QARNSRA 307 QA +RA Sbjct 301 QAARARA 307 >gi|41408057|ref|NP_960893.1| lipoyl synthase [Mycobacterium avium subsp. paratuberculosis K-10] gi|47117071|sp|P61197.1|LIPA_MYCPA RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|41396412|gb|AAS04276.1| LipA [Mycobacterium avium subsp. paratuberculosis K-10] gi|336461818|gb|EGO40674.1| lipoate synthase [Mycobacterium avium subsp. paratuberculosis S397] Length=307 Score = 568 bits (1463), Expect = 5e-160, Method: Compositional matrix adjust. Identities = 279/307 (91%), Positives = 290/307 (95%), Gaps = 0/307 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGR+LLRLEVRNA+TPIERKPPWI+ RAR+GPEYTELK+LVRREGLHTVCEEAGC Sbjct 1 MTVAPEGRKLLRLEVRNAETPIERKPPWIRVRARMGPEYTELKSLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVRAIKELNPSTGVELLIPDFNG P RLAEVF S PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRAIKELNPSTGVELLIPDFNGRPDRLAEVFGSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAFTYRRSL VLTAAR+AGLVTKSNLILGLGET DEVRTAL DLR AG Sbjct 181 VETVPRIFKRIRPAFTYRRSLDVLTAAREAGLVTKSNLILGLGETPDEVRTALADLRGAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPSARHHPVERWVKPEEFV+FAR AE LGF+GVLAGPLVRSSYRAGRLY Sbjct 241 CDIITITQYLRPSARHHPVERWVKPEEFVEFARHAEELGFSGVLAGPLVRSSYRAGRLYR 300 Query 301 QARNSRA 307 Q +RA Sbjct 301 QTARARA 307 >gi|240168288|ref|ZP_04746947.1| lipoyl synthase [Mycobacterium kansasii ATCC 12478] Length=311 Score = 563 bits (1450), Expect = 2e-158, Method: Compositional matrix adjust. Identities = 277/311 (90%), Positives = 290/311 (94%), Gaps = 0/311 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGRRLLRLEVRNAQTPIERKPPWI+ RAR+GPEYTELK+LVRREGLHTVCEEAGC Sbjct 1 MTVAPEGRRLLRLEVRNAQTPIERKPPWIRIRARMGPEYTELKSLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPA LDRDEPRRVA+SV TMGLRYATV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPATLDRDEPRRVAESVHTMGLRYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVRAIKELNP TGVELLIPDFNGE RLAEVF S PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAQTVRAIKELNPQTGVELLIPDFNGEAGRLAEVFASRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIF+RIRPAF+YRRSL VLTAARDAGLVTKSNLILGLGET DEVRTAL DL AG Sbjct 181 VETVPRIFRRIRPAFSYRRSLDVLTAARDAGLVTKSNLILGLGETPDEVRTALTDLHRAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDIVTITQYLRPS RHHPVERWV+PEEFV++A++AEGL FAGVLAGPLVRSSYRAGRLY Sbjct 241 CDIVTITQYLRPSPRHHPVERWVRPEEFVEYAQYAEGLSFAGVLAGPLVRSSYRAGRLYR 300 Query 301 QARNSRALASR 311 QAR+S A SR Sbjct 301 QARSSAASDSR 311 >gi|15827383|ref|NP_301646.1| lipoyl synthase [Mycobacterium leprae TN] gi|221229860|ref|YP_002503276.1| lipoyl synthase [Mycobacterium leprae Br4923] gi|6016508|sp|O32962.1|LIPA_MYCLE RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|254809198|sp|B8ZQJ9.1|LIPA_MYCLB RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|2342614|emb|CAB11385.1| lipoic acid synthetase [Mycobacterium leprae] gi|13092933|emb|CAC31239.1| putative lipoic acid synthetase [Mycobacterium leprae] gi|219932967|emb|CAR70953.1| putative lipoic acid synthetase [Mycobacterium leprae Br4923] Length=314 Score = 558 bits (1439), Expect = 3e-157, Method: Compositional matrix adjust. Identities = 269/310 (87%), Positives = 288/310 (93%), Gaps = 0/310 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA E RLLRLEVRNAQTPIERKPPWIKTRAR+GPEYT LKNLVRR LHTVCEEAGC Sbjct 1 MTVAPEDCRLLRLEVRNAQTPIERKPPWIKTRARMGPEYTALKNLVRRVALHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPA LDRDEPRRVA+SV+TMGLRY TV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAALDRDEPRRVAESVQTMGLRYTTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVRAIKELNPSTGVELLIPDFNG+P RLAEVF+S P+VLAHN Sbjct 121 TGVARDDLPDGGAWLYATTVRAIKELNPSTGVELLIPDFNGQPARLAEVFDSRPQVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAFTY+RSL VLTAAR+AGLVTKSNLILGLGET+DEVRTAL DLR G Sbjct 181 VETVPRIFKRIRPAFTYQRSLDVLTAAREAGLVTKSNLILGLGETADEVRTALADLRKTG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDIVTITQYLRPS RHHPVERWV+PEEFV++ ++AEGLGF+GVL GPLVRSSYRAGRLYE Sbjct 241 CDIVTITQYLRPSMRHHPVERWVRPEEFVEYTQYAEGLGFSGVLGGPLVRSSYRAGRLYE 300 Query 301 QARNSRALAS 310 QA +R + + Sbjct 301 QAAGTRTVGT 310 >gi|118617035|ref|YP_905367.1| lipoyl synthase [Mycobacterium ulcerans Agy99] gi|183983276|ref|YP_001851567.1| lipoate biosynthesis protein a LipA [Mycobacterium marinum M] gi|166230427|sp|A0PNH7.1|LIPA_MYCUA RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|238689239|sp|B2HHL4.1|LIPA_MYCMM RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|118569145|gb|ABL03896.1| lipoate biosynthesis protein a LipA [Mycobacterium ulcerans Agy99] gi|183176602|gb|ACC41712.1| lipoate biosynthesis protein a LipA [Mycobacterium marinum M] Length=324 Score = 551 bits (1420), Expect = 5e-155, Method: Compositional matrix adjust. Identities = 266/297 (90%), Positives = 283/297 (96%), Gaps = 0/297 (0%) Query 8 RRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNIFECW 67 R+LLRLEVRNAQTPIERKPPWI+TRAR+GPEYTELKNLVRREGLHTVCEEAGCPNIFECW Sbjct 18 RKLLRLEVRNAQTPIERKPPWIRTRARMGPEYTELKNLVRREGLHTVCEEAGCPNIFECW 77 Query 68 EDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGVARDD 127 EDREATFLIGGDQCTRRCDFCQIDTGKPA LDRDEPRRVA+SV TMGLRYATVTGVARDD Sbjct 78 EDREATFLIGGDQCTRRCDFCQIDTGKPAPLDRDEPRRVAESVHTMGLRYATVTGVARDD 137 Query 128 LPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVETVPRI 187 LPDGGAWLYA TVRAIKELNPSTGVELLIPDFNG+ +L EVFE+ PEVLAHNVETVPR+ Sbjct 138 LPDGGAWLYAETVRAIKELNPSTGVELLIPDFNGKADQLGEVFEARPEVLAHNVETVPRV 197 Query 188 FKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDIVTIT 247 FKRIRPAFTY+RSL VLTAAR GLVTKSNLILG+GET +EVRTAL DL DAGCDI+TIT Sbjct 198 FKRIRPAFTYQRSLDVLTAARQFGLVTKSNLILGMGETPEEVRTALVDLHDAGCDIITIT 257 Query 248 QYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQARN 304 QYLRPS RHHPVERWV+PEEFV+FA++AEGLGFAGVLAGPLVRSSYRAGRLYEQAR+ Sbjct 258 QYLRPSPRHHPVERWVRPEEFVEFAQYAEGLGFAGVLAGPLVRSSYRAGRLYEQARS 314 >gi|108800282|ref|YP_640479.1| lipoyl synthase [Mycobacterium sp. MCS] gi|119869410|ref|YP_939362.1| lipoyl synthase [Mycobacterium sp. KMS] gi|126435905|ref|YP_001071596.1| lipoyl synthase [Mycobacterium sp. JLS] 6 more sequence titles Length=325 Score = 548 bits (1411), Expect = 6e-154, Method: Compositional matrix adjust. Identities = 263/301 (88%), Positives = 281/301 (94%), Gaps = 0/301 (0%) Query 2 SVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCP 61 S A EGR+LLRLEVRNAQTPIERKPPWIKTRAR+GPEY ELK+LV+REGLHTVCEEAGCP Sbjct 13 SAAPEGRKLLRLEVRNAQTPIERKPPWIKTRARMGPEYKELKSLVKREGLHTVCEEAGCP 72 Query 62 NIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVT 121 NIFECWEDREATFLIGG+QCTRRCDFCQIDTGKP+ELDRDEPRRVA+SV+ MGLRY+TVT Sbjct 73 NIFECWEDREATFLIGGEQCTRRCDFCQIDTGKPSELDRDEPRRVAESVQAMGLRYSTVT 132 Query 122 GVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNV 181 GVARDDLPDGGAWLYA TVR IK LNP+TGVELLIPDFNG+P LA+VFES PEVLAHNV Sbjct 133 GVARDDLPDGGAWLYAETVREIKRLNPNTGVELLIPDFNGDPALLAQVFESRPEVLAHNV 192 Query 182 ETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGC 241 ETVPRIFKRIRPAF Y RSL VLTAARD LVTKSNLILG+GET DEVRTAL DL +AGC Sbjct 193 ETVPRIFKRIRPAFRYERSLAVLTAARDDNLVTKSNLILGMGETPDEVRTALVDLHEAGC 252 Query 242 DIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQ 301 DI+TITQYLRPS RHHPVERWVKPEEFV+FA+FAEGLGFAGVL+GPLVRSSYRAGRLY Q Sbjct 253 DIITITQYLRPSPRHHPVERWVKPEEFVEFAQFAEGLGFAGVLSGPLVRSSYRAGRLYAQ 312 Query 302 A 302 A Sbjct 313 A 313 >gi|118472901|ref|YP_888563.1| lipoyl synthase [Mycobacterium smegmatis str. MC2 155] gi|171472983|sp|A0R075.1|LIPA_MYCS2 RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|118174188|gb|ABK75084.1| lipoic acid synthetase [Mycobacterium smegmatis str. MC2 155] Length=314 Score = 539 bits (1388), Expect = 2e-151, Method: Compositional matrix adjust. Identities = 260/306 (85%), Positives = 280/306 (92%), Gaps = 0/306 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+V EGR+LLRLEVRNAQTPIERKPPWIKTRA++GPEYTELK LVRREGLHTVCEEAGC Sbjct 1 MTVVPEGRKLLRLEVRNAQTPIERKPPWIKTRAKMGPEYTELKGLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGG+QCTRRCDFCQIDTGKPA+LDRDEPRRVA+SV+ MGLRY+TV Sbjct 61 PNIFECWEDREATFLIGGEQCTRRCDFCQIDTGKPADLDRDEPRRVAESVQAMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR IK LNP+TGVELLIPDFNG P +L EVFES PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRYIKRLNPNTGVELLIPDFNGNPEQLEEVFESRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAF Y RSL V+TAAR+ GLVTKSNLILG+GET DEVRTAL DL DAG Sbjct 181 VETVPRIFKRIRPAFRYDRSLAVITAARNFGLVTKSNLILGMGETIDEVRTALRDLHDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPS RHHPVERWV P+EFV+ + +AEGLGFAGVLAGPLVRSSYRAG+LY Sbjct 241 CDIITITQYLRPSPRHHPVERWVHPDEFVELSAYAEGLGFAGVLAGPLVRSSYRAGKLYA 300 Query 301 QARNSR 306 QA R Sbjct 301 QAARVR 306 >gi|120401929|ref|YP_951758.1| lipoyl synthase [Mycobacterium vanbaalenii PYR-1] gi|119954747|gb|ABM11752.1| lipoic acid synthetase [Mycobacterium vanbaalenii PYR-1] Length=306 Score = 532 bits (1370), Expect = 3e-149, Method: Compositional matrix adjust. Identities = 256/305 (84%), Positives = 274/305 (90%), Gaps = 0/305 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGRRLLRLEVRNA+TPIERKPPWIK RA++GPEY ELK LVRREGLHTVCEEAGC Sbjct 1 MTVAPEGRRLLRLEVRNAETPIERKPPWIKIRAKMGPEYKELKGLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGG+QCTRRCDFCQIDTGKPAELDRDEPRRVA+SV MGLRY+TV Sbjct 61 PNIFECWEDREATFLIGGEQCTRRCDFCQIDTGKPAELDRDEPRRVAESVAAMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLY+ TVR IK LNP+TGVELLIPDFN +P +L +VFES PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYSETVRQIKALNPNTGVELLIPDFNADPAQLQQVFESRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRP F Y RSL VLT ARD GLVTKSNLILG+GET +EVR AL DL AG Sbjct 181 VETVPRIFKRIRPGFRYERSLSVLTMARDYGLVTKSNLILGMGETPEEVREALVDLHQAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDIVTITQYLRPSARHHPVERWV P+EFV+ R+A GLGFAGVLAGPLVRSSYRAG+LY Sbjct 241 CDIVTITQYLRPSARHHPVERWVHPDEFVEHERYATGLGFAGVLAGPLVRSSYRAGKLYR 300 Query 301 QARNS 305 QAR Sbjct 301 QARTQ 305 >gi|120404553|ref|YP_954382.1| lipoyl synthase [Mycobacterium vanbaalenii PYR-1] gi|119957371|gb|ABM14376.1| lipoic acid synthetase [Mycobacterium vanbaalenii PYR-1] Length=332 Score = 528 bits (1359), Expect = 6e-148, Method: Compositional matrix adjust. Identities = 254/303 (84%), Positives = 272/303 (90%), Gaps = 0/303 (0%) Query 4 AAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNI 63 A EGR+LLRLEVRNA+TPIERKPPWIKTRA++GPEY ELK LVRREGLHTVCEEAGCPNI Sbjct 14 APEGRKLLRLEVRNAETPIERKPPWIKTRAKMGPEYKELKGLVRREGLHTVCEEAGCPNI 73 Query 64 FECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGV 123 FECWEDREATFLIGG+QCTRRCDFCQIDTGKPAELDRDEPRRVA+SV MGLRY+TVTGV Sbjct 74 FECWEDREATFLIGGEQCTRRCDFCQIDTGKPAELDRDEPRRVAESVAAMGLRYSTVTGV 133 Query 124 ARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVET 183 ARDDLPDGGAWLY+ TVR IK LNP+TGVELLIPDFN +P +L +VFES PEVLAHNVET Sbjct 134 ARDDLPDGGAWLYSETVRQIKALNPNTGVELLIPDFNADPAQLQQVFESRPEVLAHNVET 193 Query 184 VPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDI 243 VPRIFKRIRP F Y RSL VLT ARD GLVTKSNLILG+GET +EVR AL DL AGCDI Sbjct 194 VPRIFKRIRPGFRYERSLSVLTMARDYGLVTKSNLILGMGETPEEVREALVDLHRAGCDI 253 Query 244 VTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQAR 303 VTITQYLRPSARHHPVERWV P+EFV+ R+A GLGFAGVLAGPLVRSSYRAG+LY Q Sbjct 254 VTITQYLRPSARHHPVERWVHPDEFVEHERYATGLGFAGVLAGPLVRSSYRAGKLYAQTI 313 Query 304 NSR 306 SR Sbjct 314 ASR 316 >gi|145223519|ref|YP_001134197.1| lipoyl synthase [Mycobacterium gilvum PYR-GCK] gi|189046607|sp|A4TBK7.1|LIPA_MYCGI RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|145216005|gb|ABP45409.1| lipoic acid synthetase [Mycobacterium gilvum PYR-GCK] Length=317 Score = 527 bits (1357), Expect = 1e-147, Method: Compositional matrix adjust. Identities = 253/310 (82%), Positives = 275/310 (89%), Gaps = 0/310 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 MS+A +GR+LLRLEVRNA+TPIERKPPWIKTRA++GPEY ELK LVRREGLHTVCEEAGC Sbjct 1 MSIAPDGRKLLRLEVRNAETPIERKPPWIKTRAKMGPEYKELKALVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGG+QCTRRCDFCQIDTGKPA+LDRDEPRRVA+SV+ MGLRY+TV Sbjct 61 PNIFECWEDREATFLIGGEQCTRRCDFCQIDTGKPADLDRDEPRRVAESVQAMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR IK LNP+TGVELLIPDFN +P +L VFES PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRQIKALNPNTGVELLIPDFNADPDQLRAVFESRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRP F Y RSL V+TAARD GLVTKSNLILG+GET +EVR AL DL DAG Sbjct 181 VETVPRIFKRIRPGFRYERSLAVITAARDYGLVTKSNLILGMGETPEEVRAALHDLHDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDIVTITQYLRPS RHHPVERWV P+EFV R+A +GFAGVLAGPLVRSSYRAG+LY Sbjct 241 CDIVTITQYLRPSPRHHPVERWVHPDEFVDHERYATEIGFAGVLAGPLVRSSYRAGKLYA 300 Query 301 QARNSRALAS 310 Q R+ S Sbjct 301 QTVAKRSAVS 310 >gi|315443865|ref|YP_004076744.1| lipoate synthase [Mycobacterium sp. Spyr1] gi|315262168|gb|ADT98909.1| lipoate synthase [Mycobacterium sp. Spyr1] Length=317 Score = 526 bits (1355), Expect = 1e-147, Method: Compositional matrix adjust. Identities = 252/310 (82%), Positives = 275/310 (89%), Gaps = 0/310 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 MS+A +GR+LLRLEVRNA+TPIERKPPWIKTRA++GPEY ELK LVRREGLHTVCEEAGC Sbjct 1 MSIAPDGRKLLRLEVRNAETPIERKPPWIKTRAKMGPEYKELKGLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGG+QCTRRCDFCQIDTGKPA+LDRDEPRRVA+SV+ MGLRY+TV Sbjct 61 PNIFECWEDREATFLIGGEQCTRRCDFCQIDTGKPADLDRDEPRRVAESVQAMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR IK LNP+TGVELLIPDFN +P +L VFES PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRQIKALNPNTGVELLIPDFNADPDQLRAVFESRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRP F Y RS+ V+TAARD GLVTKSNLILG+GET +EVR AL DL DAG Sbjct 181 VETVPRIFKRIRPGFRYERSVAVITAARDYGLVTKSNLILGMGETPEEVRAALHDLHDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDIVTITQYLRPS RHHPVERWV P+EFV R+A +GFAGVLAGPLVRSSYRAG+LY Sbjct 241 CDIVTITQYLRPSPRHHPVERWVHPDEFVDHERYANEIGFAGVLAGPLVRSSYRAGKLYA 300 Query 301 QARNSRALAS 310 Q R+ S Sbjct 301 QTVAKRSAVS 310 >gi|340525485|gb|AEK40690.1| lipoyl synthase [Amycolatopsis mediterranei S699] Length=333 Score = 523 bits (1346), Expect = 2e-146, Method: Compositional matrix adjust. Identities = 249/306 (82%), Positives = 274/306 (90%), Gaps = 0/306 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 MS A EGR+LLRLEVRN++TPIE+KP WIKTR R+GPE+TELK LVRREGLHTVCEEAGC Sbjct 1 MSAAPEGRKLLRLEVRNSETPIEKKPSWIKTRVRMGPEFTELKGLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDR EPR+VA+SV+ MGLRY+TV Sbjct 61 PNIYECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRTEPRKVAESVQAMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR I LNP TGVELLIPDFN EP +LAEVF S PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRQIHALNPGTGVELLIPDFNAEPAQLAEVFGSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRP F Y RSL V+TAAR+AGLVTKSNLILG+GET DEV A+ DL DAG Sbjct 181 VETVPRIFKRIRPGFRYARSLEVITAAREAGLVTKSNLILGMGETPDEVAPAMRDLVDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 C+I+TITQYLRPSARHHPV+RWVKPEEFV+ ++ AE +GFAGV+AGPLVRSSYRAGRLY Sbjct 241 CEILTITQYLRPSARHHPVDRWVKPEEFVEHSKAAEAMGFAGVMAGPLVRSSYRAGRLYA 300 Query 301 QARNSR 306 Q + R Sbjct 301 QTKAHR 306 >gi|325677046|ref|ZP_08156717.1| lipoic acid synthetase [Rhodococcus equi ATCC 33707] gi|325552208|gb|EGD21899.1| lipoic acid synthetase [Rhodococcus equi ATCC 33707] Length=338 Score = 522 bits (1345), Expect = 3e-146, Method: Compositional matrix adjust. Identities = 249/310 (81%), Positives = 279/310 (90%), Gaps = 2/310 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGR+LLR+E RNA+TPIERKP WI+TRA++GPEYTELK LV+ EGLHTVCEEAGC Sbjct 1 MTVAPEGRKLLRIETRNAETPIERKPNWIRTRAKMGPEYTELKGLVKNEGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGG+QCTRRCDFCQIDTGKPA LDRDEPRRVA+SV+ MGLRY+T+ Sbjct 61 PNIYECWEDREATFLIGGEQCTRRCDFCQIDTGKPAALDRDEPRRVAESVKAMGLRYSTI 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR I +NP TGVE LIPDFNG+P LAEVFES PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRQIHAMNPGTGVENLIPDFNGKPDLLAEVFESRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 +ETVPRIFKRIRPAF Y RSLGV+TAAR+ GLVTKSNLILG+GET +EV+ A+ DL +AG Sbjct 181 LETVPRIFKRIRPAFRYERSLGVITAAREFGLVTKSNLILGMGETPEEVQQAMVDLHEAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPS RHHPVERWVKPEEFV+ +R AE +GFAGV+AGPLVRSSYRAGRLY Sbjct 241 CDIITITQYLRPSPRHHPVERWVKPEEFVEHSRAAEEIGFAGVMAGPLVRSSYRAGRLYA 300 Query 301 Q--ARNSRAL 308 Q AR+ RAL Sbjct 301 QAMARHGRAL 310 >gi|312140208|ref|YP_004007544.1| lipoyl synthase lipa [Rhodococcus equi 103S] gi|311889547|emb|CBH48864.1| lipoyl synthase LipA [Rhodococcus equi 103S] Length=338 Score = 522 bits (1344), Expect = 3e-146, Method: Compositional matrix adjust. Identities = 249/310 (81%), Positives = 279/310 (90%), Gaps = 2/310 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGR+LLR+E RNA+TPIERKP WI+TRA++GPEYTELK LV+ EGLHTVCEEAGC Sbjct 1 MTVAPEGRKLLRIETRNAETPIERKPNWIRTRAKMGPEYTELKGLVKNEGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGG+QCTRRCDFCQIDTGKPA LDRDEPRRVA+SV+ MGLRY+T+ Sbjct 61 PNIYECWEDREATFLIGGEQCTRRCDFCQIDTGKPAALDRDEPRRVAESVKAMGLRYSTI 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR I +NP TGVE LIPDFNG+P LAEVFES PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRQIHAMNPGTGVENLIPDFNGKPDLLAEVFESRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 +ETVPRIFKRIRPAF Y RSLGV+TAAR+ GLVTKSNLILG+GET +EV+ A+ DL +AG Sbjct 181 LETVPRIFKRIRPAFRYERSLGVITAAREFGLVTKSNLILGMGETPEEVQQAMVDLHEAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPS RHHPVERWVKPEEFV+ +R AE +GFAGV+AGPLVRSSYRAGRLY Sbjct 241 CDIITITQYLRPSPRHHPVERWVKPEEFVEHSRAAEEIGFAGVMAGPLVRSSYRAGRLYA 300 Query 301 Q--ARNSRAL 308 Q AR+ RAL Sbjct 301 QAMARHGRAL 310 >gi|111018167|ref|YP_701139.1| lipoyl synthase [Rhodococcus jostii RHA1] gi|110817697|gb|ABG92981.1| lipoyl synthase [Rhodococcus jostii RHA1] Length=346 Score = 521 bits (1343), Expect = 4e-146, Method: Compositional matrix adjust. Identities = 245/302 (82%), Positives = 276/302 (92%), Gaps = 0/302 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 ++VA EGR+LLRLE+RNA+TPIERKP WIKTRA++GPEY+ELK+LV+REGLHTVCEEAGC Sbjct 11 VTVAPEGRKLLRLEIRNAETPIERKPNWIKTRAKMGPEYSELKSLVKREGLHTVCEEAGC 70 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGG+QCTRRCDFCQIDTGKP +LDRDEPRRVA+SV+ MGLRY+T+ Sbjct 71 PNIYECWEDREATFLIGGEQCTRRCDFCQIDTGKPDDLDRDEPRRVAESVQAMGLRYSTI 130 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR I +LNP TGVELLIPDFN +P +LAEVF + PEVLAHN Sbjct 131 TGVARDDLPDGGAWLYAETVRLIHQLNPGTGVELLIPDFNAKPDQLAEVFSTRPEVLAHN 190 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAF Y+RSL V+TAAR+ LVTKSNLILG+GET DEV AL DL DAG Sbjct 191 VETVPRIFKRIRPAFRYQRSLDVITAAREDNLVTKSNLILGMGETPDEVTQALHDLHDAG 250 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPS RHHPVERWVKPEEFV+ ++ AE +GFAGV+AGPLVRSSYRAGRLY Sbjct 251 CDIITITQYLRPSPRHHPVERWVKPEEFVEHSKTAEEIGFAGVMAGPLVRSSYRAGRLYA 310 Query 301 QA 302 QA Sbjct 311 QA 312 >gi|300783739|ref|YP_003764030.1| lipoic acid synthetase [Amycolatopsis mediterranei U32] gi|299793253|gb|ADJ43628.1| lipoic acid synthetase [Amycolatopsis mediterranei U32] gi|340525129|gb|AEK40334.1| lipoyl synthase [Amycolatopsis mediterranei S699] Length=333 Score = 521 bits (1343), Expect = 4e-146, Method: Compositional matrix adjust. Identities = 248/306 (82%), Positives = 274/306 (90%), Gaps = 0/306 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 MS + EGR+LLRLEVRN++TPIE+KP WIKTR R+GPE+TELK LVRREGLHTVCEEAGC Sbjct 1 MSASPEGRKLLRLEVRNSETPIEKKPSWIKTRVRMGPEFTELKGLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDR EPR+VA+SV+ MGLRY+TV Sbjct 61 PNIYECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRTEPRKVAESVQAMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR I LNP TGVELLIPDFN EP +LAEVF S PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRQIHALNPGTGVELLIPDFNAEPAQLAEVFGSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRP F Y RSL V+TAAR+AGLVTKSNLILG+GET DEV A+ DL DAG Sbjct 181 VETVPRIFKRIRPGFRYARSLEVITAAREAGLVTKSNLILGMGETPDEVAPAMRDLVDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 C+I+TITQYLRPSARHHPV+RWVKPEEFV+ ++ AE +GFAGV+AGPLVRSSYRAGRLY Sbjct 241 CEILTITQYLRPSARHHPVDRWVKPEEFVEHSKAAEAMGFAGVMAGPLVRSSYRAGRLYA 300 Query 301 QARNSR 306 Q + R Sbjct 301 QTKGYR 306 >gi|226360295|ref|YP_002778073.1| lipoyl synthase [Rhodococcus opacus B4] gi|226238780|dbj|BAH49128.1| lipoyl synthase [Rhodococcus opacus B4] Length=336 Score = 521 bits (1341), Expect = 7e-146, Method: Compositional matrix adjust. Identities = 246/302 (82%), Positives = 274/302 (91%), Gaps = 0/302 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+VA EGR+LLRLE+RNA+TPIERKP WIKTRA++GPEY+ELK LV+REGLHTVCEEAGC Sbjct 1 MTVAPEGRKLLRLEIRNAETPIERKPNWIKTRAKMGPEYSELKGLVKREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGG+QCTRRCDFCQIDTGKP +LDRDEPRRVA+SV+ MGLRY+T+ Sbjct 61 PNIYECWEDREATFLIGGEQCTRRCDFCQIDTGKPTDLDRDEPRRVAESVQAMGLRYSTI 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR I LNP TGVE LIPDFNG+P LAEVF+S PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRQIHHLNPGTGVENLIPDFNGKPDLLAEVFDSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 +ETVPRIFKRIRPAF Y RSLGV+TAARD GLVTKSNLILG+GET +EV A+ DL AG Sbjct 181 LETVPRIFKRIRPAFRYERSLGVITAARDFGLVTKSNLILGMGETPEEVHQAMLDLHAAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPS RHHPVERWVKPEEFV+ ++ AE +GFAGV+AGPLVRSSYRAGRLY Sbjct 241 CDILTITQYLRPSPRHHPVERWVKPEEFVEHSKAAEEIGFAGVMAGPLVRSSYRAGRLYA 300 Query 301 QA 302 QA Sbjct 301 QA 302 >gi|226307107|ref|YP_002767067.1| lipoyl synthase [Rhodococcus erythropolis PR4] gi|229490277|ref|ZP_04384119.1| lipoyl synthase [Rhodococcus erythropolis SK121] gi|226186224|dbj|BAH34328.1| lipoyl synthase [Rhodococcus erythropolis PR4] gi|229322809|gb|EEN88588.1| lipoyl synthase [Rhodococcus erythropolis SK121] Length=336 Score = 516 bits (1329), Expect = 2e-144, Method: Compositional matrix adjust. Identities = 244/302 (81%), Positives = 271/302 (90%), Gaps = 0/302 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M++A EGR+LLRLE+RNA+TPIERKP WIKTRA++GPEYTELK LV+REGLHTVCEEAGC Sbjct 1 MTIAPEGRKLLRLEIRNAETPIERKPNWIKTRAKMGPEYTELKGLVKREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGG+QCTRRCDFCQIDTGKP LDRDEPRRVA+SV+ MGLRY+T+ Sbjct 61 PNIYECWEDREATFLIGGEQCTRRCDFCQIDTGKPEALDRDEPRRVAESVQAMGLRYSTI 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR I ELNP TGVE L+PDFNG+P L EVF S PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRKIHELNPGTGVENLVPDFNGKPELLDEVFASRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 +ETVPRIFKRIRPAF Y+RSL V+TAARD GLVTKSNLILG+GET +EV A+ DL AG Sbjct 181 LETVPRIFKRIRPAFRYQRSLDVITAARDYGLVTKSNLILGMGETPEEVTEAMADLHAAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPS RHHPVERWVKPEEFV ++ AE +GFAGV+AGPLVRSSYRAGRLY Sbjct 241 CDILTITQYLRPSPRHHPVERWVKPEEFVAHSKAAEEMGFAGVMAGPLVRSSYRAGRLYA 300 Query 301 QA 302 QA Sbjct 301 QA 302 >gi|54023654|ref|YP_117896.1| lipoyl synthase [Nocardia farcinica IFM 10152] gi|81602900|sp|Q5YZ59.1|LIPA_NOCFA RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|54015162|dbj|BAD56532.1| putative lipoic acid synthetase [Nocardia farcinica IFM 10152] Length=352 Score = 516 bits (1328), Expect = 2e-144, Method: Compositional matrix adjust. Identities = 244/298 (82%), Positives = 271/298 (91%), Gaps = 0/298 (0%) Query 5 AEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNIF 64 A GR+LLR+E RNAQTPIERKP WI+TRA +GPEY+ELK LV+REGLHTVCEEAGCPNIF Sbjct 21 ANGRKLLRIEARNAQTPIERKPKWIRTRATMGPEYSELKGLVKREGLHTVCEEAGCPNIF 80 Query 65 ECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGVA 124 ECWEDREATFLIGG+QCTRRCDFCQIDTGKPA LDRDEPRRVA+SV+ MGLRY+T+TGVA Sbjct 81 ECWEDREATFLIGGEQCTRRCDFCQIDTGKPAALDRDEPRRVAESVQAMGLRYSTITGVA 140 Query 125 RDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVETV 184 RDDL DGGAWLYA TVRAIK LNP+TGVELLIPDFN +P +LAEVF + PEVLAHN+ETV Sbjct 141 RDDLEDGGAWLYAETVRAIKRLNPATGVELLIPDFNADPDQLAEVFSARPEVLAHNLETV 200 Query 185 PRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDIV 244 PRIFKRIRPAF Y RSL VLTAAR+AGLVTKSNLILG+GET +EV A+ DL +AGCDI+ Sbjct 201 PRIFKRIRPAFRYERSLSVLTAAREAGLVTKSNLILGMGETPEEVTEAMRDLHEAGCDIL 260 Query 245 TITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQA 302 TITQYLRPS RHHPV+RWVKPEEFV+ +R AE +GFAGV+AGPLVRSSYRAGRLY QA Sbjct 261 TITQYLRPSPRHHPVDRWVKPEEFVEHSRVAEEIGFAGVMAGPLVRSSYRAGRLYAQA 318 >gi|169629029|ref|YP_001702678.1| lipoyl synthase [Mycobacterium abscessus ATCC 19977] gi|169240996|emb|CAM62024.1| Probable lipoic acid synthetase LipA [Mycobacterium abscessus] Length=329 Score = 516 bits (1328), Expect = 2e-144, Method: Compositional matrix adjust. Identities = 244/297 (83%), Positives = 272/297 (92%), Gaps = 0/297 (0%) Query 6 EGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNIFE 65 E R+LLRLEVRNAQTPIERKP WI+TRA++GPEY ELK+LVR GLHTVCEEAGCPNIFE Sbjct 3 EPRKLLRLEVRNAQTPIERKPDWIRTRAKMGPEYKELKSLVRSGGLHTVCEEAGCPNIFE 62 Query 66 CWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGVAR 125 CWEDREATFLIGG+QCTRRCDFCQIDTGKPA+LDRDEPRRVA+SV TMGLRY+TVTGVAR Sbjct 63 CWEDREATFLIGGEQCTRRCDFCQIDTGKPADLDRDEPRRVAESVHTMGLRYSTVTGVAR 122 Query 126 DDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVETVP 185 DDLPDGGAWLYA TVR IK+LNP+TGVELLIPDFN P +L EVF S PEVLAHN+ETVP Sbjct 123 DDLPDGGAWLYAETVRYIKDLNPATGVELLIPDFNAIPAQLDEVFASRPEVLAHNLETVP 182 Query 186 RIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDIVT 245 R+F+RIRPAF+Y RSL V+TAAR+A LVTKSNLILG+GET+DE+R AL L +AGCDI+T Sbjct 183 RVFRRIRPAFSYERSLSVITAAREAQLVTKSNLILGMGETNDEIREALVALHEAGCDIIT 242 Query 246 ITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQA 302 ITQYLRPS RHHPV+RWVKP+EFV+ + FAEGLGFAGV+AGPLVRSSYRAGRLY QA Sbjct 243 ITQYLRPSPRHHPVDRWVKPQEFVELSEFAEGLGFAGVMAGPLVRSSYRAGRLYAQA 299 >gi|333918930|ref|YP_004492511.1| lipoyl synthase [Amycolicicoccus subflavus DQS3-9A1] gi|333481151|gb|AEF39711.1| Lipoyl synthase [Amycolicicoccus subflavus DQS3-9A1] Length=355 Score = 516 bits (1328), Expect = 3e-144, Method: Compositional matrix adjust. Identities = 247/307 (81%), Positives = 271/307 (89%), Gaps = 0/307 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 +++A EGR+LLR+E RNA+TPIERKP WIKTRA++GPEYTELK LVRREGLHTVCEEAGC Sbjct 20 VTIAPEGRKLLRIEARNAETPIERKPNWIKTRAKMGPEYTELKGLVRREGLHTVCEEAGC 79 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVA+SV+ MGLRY+T+ Sbjct 80 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVAESVQAMGLRYSTI 139 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR I LNP TGVELLIPDFN +P +L EVF S PEVLAHN Sbjct 140 TGVARDDLPDGGAWLYAETVRQIHALNPGTGVELLIPDFNADPEQLDEVFGSRPEVLAHN 199 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPR+F+RIRPAF Y+RSL V++AARD GLVTKSNLILG+GET +EV AL DLR AG Sbjct 200 VETVPRVFRRIRPAFRYQRSLDVISAARDVGLVTKSNLILGMGETPEEVSEALQDLRTAG 259 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRPS RHHPVERWVKPEEFV + A LGFAGV+AGPLVRSSYRAGRLY Sbjct 260 CDIITITQYLRPSPRHHPVERWVKPEEFVAHSDTARDLGFAGVMAGPLVRSSYRAGRLYT 319 Query 301 QARNSRA 307 A R Sbjct 320 HAVAERG 326 >gi|326382496|ref|ZP_08204187.1| lipoyl synthase [Gordonia neofelifaecis NRRL B-59395] gi|326198615|gb|EGD55798.1| lipoyl synthase [Gordonia neofelifaecis NRRL B-59395] Length=348 Score = 513 bits (1321), Expect = 2e-143, Method: Compositional matrix adjust. Identities = 249/308 (81%), Positives = 272/308 (89%), Gaps = 2/308 (0%) Query 4 AAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNI 63 A GR+LLRLEVRNAQTPIERKP WIKTRA +GPEYTELK LVR EGLHTVCEEAGCPNI Sbjct 16 APAGRKLLRLEVRNAQTPIERKPKWIKTRATMGPEYTELKGLVRSEGLHTVCEEAGCPNI 75 Query 64 FECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGV 123 +ECWEDREATFLIGG+QCTRRCDFCQIDTGKPA+LDRDEPRRVA+SV++MGLRY+T+TGV Sbjct 76 YECWEDREATFLIGGEQCTRRCDFCQIDTGKPADLDRDEPRRVAESVQSMGLRYSTITGV 135 Query 124 ARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVET 183 ARDDLPD GAWLYA TVR I ELNP TGVE LIPDF+ +P L EVF S PEVLAHN+ET Sbjct 136 ARDDLPDEGAWLYAETVRKIHELNPGTGVENLIPDFHAKPDLLDEVFSSRPEVLAHNLET 195 Query 184 VPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDI 243 VPRIFK IRPAF Y RSL VLT ARD GLVTKSNLILG+GET DEVR +L DL +AGCDI Sbjct 196 VPRIFKSIRPAFRYERSLEVLTRARDYGLVTKSNLILGMGETPDEVRESLRDLHEAGCDI 255 Query 244 VTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQ-- 301 VTITQYLRPS RHHPVERWVKPEEFV+ +++AE +GFAGV+AGPLVRSSYRAGRLY Q Sbjct 256 VTITQYLRPSVRHHPVERWVKPEEFVEHSQYAEEIGFAGVMAGPLVRSSYRAGRLYAQAM 315 Query 302 ARNSRALA 309 AR+ R LA Sbjct 316 ARHGRELA 323 >gi|229780997|ref|YP_001103870.2| lipoyl synthase [Saccharopolyspora erythraea NRRL 2338] gi|291004370|ref|ZP_06562343.1| lipoyl synthase [Saccharopolyspora erythraea NRRL 2338] gi|172044193|sp|A4FA70.2|LIPA_SACEN RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA Length=333 Score = 513 bits (1320), Expect = 2e-143, Method: Compositional matrix adjust. Identities = 248/308 (81%), Positives = 271/308 (88%), Gaps = 0/308 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+ A EGR+LLRLEVRN+QTPIE+KP WIKTRAR+GPEY ELK LV+REGLHTVCEEAGC Sbjct 1 MTAAPEGRKLLRLEVRNSQTPIEKKPSWIKTRARMGPEYQELKGLVKREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELD +EPRRVA+SV+ MGLRY+TV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDVEEPRRVAESVQAMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDL DGGAWLYA TVR I +LNP TGVELLIPDFN +P +LAEVF S PEVLAHN Sbjct 121 TGVARDDLEDGGAWLYAETVRQIHQLNPGTGVELLIPDFNADPGQLAEVFGSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRPAF Y RSL V+T AR+ GLVTKSNLILG+GET +EV AL DLR+AG Sbjct 181 VETVPRIFKRIRPAFRYERSLEVITRAREDGLVTKSNLILGMGETPEEVTEALRDLREAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 DI+TITQYLRPS RHHPVERWVKPEEFV+ R AE LGF GV+AGPLVRSSYRAGRLY Sbjct 241 TDIITITQYLRPSPRHHPVERWVKPEEFVEHTRTAEELGFPGVMAGPLVRSSYRAGRLYA 300 Query 301 QARNSRAL 308 +A R + Sbjct 301 KATEHRGM 308 >gi|343924148|ref|ZP_08763711.1| lipoyl synthase [Gordonia alkanivorans NBRC 16433] gi|343765953|dbj|GAA10637.1| lipoyl synthase [Gordonia alkanivorans NBRC 16433] Length=365 Score = 512 bits (1319), Expect = 2e-143, Method: Compositional matrix adjust. Identities = 244/301 (82%), Positives = 271/301 (91%), Gaps = 0/301 (0%) Query 2 SVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCP 61 S A EGR+LLRLEVRNAQTPIERKP WIKTRA +GPE+TELK LV+REGLHTVCEEAGCP Sbjct 31 SPAPEGRKLLRLEVRNAQTPIERKPSWIKTRATMGPEFTELKGLVKREGLHTVCEEAGCP 90 Query 62 NIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVT 121 NI+ECWEDREATFLIGG+QCTRRCDFCQIDTGKPA LDRDEPRRVA+SV+ MGLRY+T+T Sbjct 91 NIYECWEDREATFLIGGEQCTRRCDFCQIDTGKPAALDRDEPRRVAESVQAMGLRYSTIT 150 Query 122 GVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNV 181 GVARDDLPD GAWLYA TVRAI LNP TGVE LIPDF+ +P LAEVF++ PEVLAHN+ Sbjct 151 GVARDDLPDEGAWLYAETVRAIHRLNPGTGVENLIPDFHAKPDLLAEVFDARPEVLAHNL 210 Query 182 ETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGC 241 ETVPRIFKRIRPAF Y RSL V+TAARD GLVTKSNLILG+GET +EV++A+ DL +AGC Sbjct 211 ETVPRIFKRIRPAFRYERSLEVITAARDFGLVTKSNLILGMGETPEEVQSAIIDLHEAGC 270 Query 242 DIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQ 301 DI+TITQYLRPS RHHPVERWVKPEEFV + FA+ +GFAGV+AGPLVRSSYRAGRLY Q Sbjct 271 DILTITQYLRPSPRHHPVERWVKPEEFVDHSEFAQEIGFAGVMAGPLVRSSYRAGRLYAQ 330 Query 302 A 302 A Sbjct 331 A 331 >gi|229820350|ref|YP_002881876.1| lipoyl synthase [Beutenbergia cavernae DSM 12333] gi|259494928|sp|C5C4Y6.1|LIPA_BEUC1 RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|229566263|gb|ACQ80114.1| lipoic acid synthetase [Beutenbergia cavernae DSM 12333] Length=332 Score = 510 bits (1314), Expect = 1e-142, Method: Compositional matrix adjust. Identities = 246/308 (80%), Positives = 268/308 (88%), Gaps = 0/308 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M++A EGRRLLR+E RNA PIE+KPPWIKTRA +GPEYTEL++LVRREGLHTVCEEAGC Sbjct 1 MTIAPEGRRLLRVEARNAAVPIEKKPPWIKTRATMGPEYTELRSLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPA+ D DEPRRVA+SV+ MGLRY+TV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPADFDADEPRRVAESVQAMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDL DGGAWLYA TVR I LNP TGVELLIPDFN EP +LAEVF S PEVLAHN Sbjct 121 TGVARDDLADGGAWLYAETVRQIHALNPGTGVELLIPDFNAEPDQLAEVFSSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 +ETVPR+FKRIRP F Y RSL VLTAARDAGLVTKSNLILG+GET+ E AL DL AG Sbjct 181 LETVPRVFKRIRPGFRYARSLSVLTAARDAGLVTKSNLILGMGETTAEAVEALADLHAAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CD+VTITQYLRPS RHHPVERWVKPEEFV+ + AE +GF GV+AGPLVRSSYRAGRL+ Sbjct 241 CDLVTITQYLRPSPRHHPVERWVKPEEFVELSDEAERIGFLGVMAGPLVRSSYRAGRLWG 300 Query 301 QARNSRAL 308 QA R L Sbjct 301 QAMARRGL 308 >gi|302525064|ref|ZP_07277406.1| lipoyl synthase [Streptomyces sp. AA4] gi|302433959|gb|EFL05775.1| lipoyl synthase [Streptomyces sp. AA4] Length=334 Score = 509 bits (1312), Expect = 2e-142, Method: Compositional matrix adjust. Identities = 243/306 (80%), Positives = 267/306 (88%), Gaps = 0/306 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 MS EGR+LLRLEVRN++TPIE+KP WIKTR R+GPE+TELK LVRREGLHTVCEEAGC Sbjct 1 MSAQPEGRKLLRLEVRNSETPIEKKPSWIKTRVRMGPEFTELKGLVRREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGGDQCTRRCDFCQIDTGKPA LDR EPR+VA+SV+ MGLRY+T+ Sbjct 61 PNIYECWEDREATFLIGGDQCTRRCDFCQIDTGKPAALDRTEPRKVAESVQAMGLRYSTI 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDL DGGAWLYA TVR I LNP TGVELLIPDFN EP +LAEVF S PEVLAHN Sbjct 121 TGVARDDLADGGAWLYAETVRQIHALNPGTGVELLIPDFNAEPDQLAEVFGSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRP F Y RSL V+T AR AGLVTKSNLILG+GET +EV AL DL DAG Sbjct 181 VETVPRIFKRIRPGFRYARSLDVITQARAAGLVTKSNLILGMGETPEEVTVALQDLFDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 C+I+TITQYLRPS RHHPV+RWVKPEEFV+ A+ AE +GF GV+AGPLVRSSYRAGRLY Sbjct 241 CEIITITQYLRPSPRHHPVDRWVKPEEFVEHAKTAEAIGFPGVMAGPLVRSSYRAGRLYA 300 Query 301 QARNSR 306 Q + R Sbjct 301 QTKAHR 306 >gi|302525317|ref|ZP_07277659.1| lipoyl synthase [Streptomyces sp. AA4] gi|302434212|gb|EFL06028.1| lipoyl synthase [Streptomyces sp. AA4] Length=336 Score = 509 bits (1310), Expect = 3e-142, Method: Compositional matrix adjust. Identities = 243/306 (80%), Positives = 268/306 (88%), Gaps = 0/306 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 +S A EGR+LLRLEVRN++TPIE+KP WIKTR R+GPE+TELK LVRREGLHTVCEEAGC Sbjct 4 VSAAPEGRKLLRLEVRNSETPIEKKPSWIKTRVRMGPEFTELKGLVRREGLHTVCEEAGC 63 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGGDQCTRRCDFCQIDTGKPA LDR EPR+VA+SV+ MGLRY+T+ Sbjct 64 PNIYECWEDREATFLIGGDQCTRRCDFCQIDTGKPAALDRTEPRKVAESVQAMGLRYSTI 123 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDL DGGAWLYA TVR I LNP TGVELLIPDFN EP +LAEVF S PEVLAHN Sbjct 124 TGVARDDLADGGAWLYAETVRQIHALNPGTGVELLIPDFNAEPDQLAEVFGSRPEVLAHN 183 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFKRIRP F Y RSL V+T AR AGLVTKSNLILG+GET +EV AL DL DAG Sbjct 184 VETVPRIFKRIRPGFRYARSLDVITQARAAGLVTKSNLILGMGETPEEVTVALQDLFDAG 243 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 C+I+TITQYLRPS RHHPV+RWVKPEEFV+ A+ AE +GF GV+AGPLVRSSYRAGRLY Sbjct 244 CEIITITQYLRPSPRHHPVDRWVKPEEFVEHAKTAEAIGFPGVMAGPLVRSSYRAGRLYA 303 Query 301 QARNSR 306 Q + R Sbjct 304 QTKAHR 309 >gi|300784074|ref|YP_003764365.1| lipoic acid synthetase [Amycolatopsis mediterranei U32] gi|299793588|gb|ADJ43963.1| lipoic acid synthetase [Amycolatopsis mediterranei U32] Length=323 Score = 508 bits (1309), Expect = 3e-142, Method: Compositional matrix adjust. Identities = 241/296 (82%), Positives = 266/296 (90%), Gaps = 0/296 (0%) Query 11 LRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNIFECWEDR 70 +RLEVRN++TPIE+KP WIKTR R+GPE+TELK LVRREGLHTVCEEAGCPNI+ECWEDR Sbjct 1 MRLEVRNSETPIEKKPSWIKTRVRMGPEFTELKGLVRREGLHTVCEEAGCPNIYECWEDR 60 Query 71 EATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGVARDDLPD 130 EATFLIGGDQCTRRCDFCQIDTGKPAELDR EPR+VA+SV+ MGLRY+TVTGVARDDLPD Sbjct 61 EATFLIGGDQCTRRCDFCQIDTGKPAELDRTEPRKVAESVQAMGLRYSTVTGVARDDLPD 120 Query 131 GGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVETVPRIFKR 190 GGAWLYA TVR I LNP TGVELLIPDFN EP +LAEVF S PEVLAHNVETVPRIFKR Sbjct 121 GGAWLYAETVRQIHALNPGTGVELLIPDFNAEPAQLAEVFGSRPEVLAHNVETVPRIFKR 180 Query 191 IRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDIVTITQYL 250 IRP F Y RSL V+TAAR+AGLVTKSNLILG+GET DEV A+ DL DAGC+I+TITQYL Sbjct 181 IRPGFRYARSLEVITAAREAGLVTKSNLILGMGETPDEVAPAMRDLVDAGCEILTITQYL 240 Query 251 RPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQARNSR 306 RPSARHHPV+RWVKPEEFV+ ++ AE +GFAGV+AGPLVRSSYRAGRLY Q + R Sbjct 241 RPSARHHPVDRWVKPEEFVEHSKAAEAMGFAGVMAGPLVRSSYRAGRLYAQTKAHR 296 >gi|331698337|ref|YP_004334576.1| Lipoyl synthase [Pseudonocardia dioxanivorans CB1190] gi|326953026|gb|AEA26723.1| Lipoyl synthase [Pseudonocardia dioxanivorans CB1190] Length=334 Score = 508 bits (1309), Expect = 4e-142, Method: Compositional matrix adjust. Identities = 244/306 (80%), Positives = 268/306 (88%), Gaps = 0/306 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M++A EGR+LLRLEVRN++TPIERKP WI+TRAR GP+YTELK LVR GLHTVCEEAGC Sbjct 1 MTIAPEGRKLLRLEVRNSETPIERKPSWIRTRARTGPQYTELKGLVRTGGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGG+QCTRRCDFCQIDTGKPAELDRDEPRRVA+SV MGLRY+TV Sbjct 61 PNIYECWEDREATFLIGGEQCTRRCDFCQIDTGKPAELDRDEPRRVAESVAQMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR I LNP TGVELLIPDF +L EVF++ PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRQIHALNPGTGVELLIPDFTNTDAQLTEVFDARPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 +ETVPRIFKRIRPAF Y RSL V+T AR AGLVTKSNLILG+GET DEV AL DL +AG Sbjct 181 LETVPRIFKRIRPAFRYDRSLQVITKARAAGLVTKSNLILGMGETPDEVTAALADLHEAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 C+I+TITQYLRPSARHHPVERWVKPEEFV+ A AE +GFAGV+AGPLVRSSYRAGRLY Sbjct 241 CEIITITQYLRPSARHHPVERWVKPEEFVEHAETAERIGFAGVMAGPLVRSSYRAGRLYA 300 Query 301 QARNSR 306 Q +R Sbjct 301 QTVAAR 306 >gi|302546040|ref|ZP_07298382.1| lipoyl synthase [Streptomyces hygroscopicus ATCC 53653] gi|302463658|gb|EFL26751.1| lipoyl synthase [Streptomyces himastatinicus ATCC 53653] Length=317 Score = 506 bits (1304), Expect = 1e-141, Method: Compositional matrix adjust. Identities = 239/306 (79%), Positives = 270/306 (89%), Gaps = 0/306 (0%) Query 2 SVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCP 61 +VA +GR++LRLEVRN+QTPIERKP WIKTRA++GPEYTEL LV+REGLHTVC+EAGCP Sbjct 6 AVAPDGRKMLRLEVRNSQTPIERKPEWIKTRAKMGPEYTELHGLVKREGLHTVCQEAGCP 65 Query 62 NIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVT 121 NIFECWEDREATFLIGGDQCTRRCDFCQIDTGKP LDRDEPRRVA+SV+TM LRYAT+T Sbjct 66 NIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPQPLDRDEPRRVAESVQTMELRYATIT 125 Query 122 GVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNV 181 GVARDDL DGGAWLYA TVR I L P TGVELLIPDFN +P +LAEVF S PEVLAHNV Sbjct 126 GVARDDLEDGGAWLYAETVRQIHSLMPDTGVELLIPDFNADPDQLAEVFSSRPEVLAHNV 185 Query 182 ETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGC 241 ETVPRIFKRIRP F Y RSL V+T AR+AGLVTKSNLILG+GE +E+ AL DL DAGC Sbjct 186 ETVPRIFKRIRPGFRYERSLEVITKAREAGLVTKSNLILGMGEEREEISQALQDLYDAGC 245 Query 242 DIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQ 301 +++TITQYLRPSARHHPVERWVKP+EFV+ A+ +G+AGV++GPLVRSSYRAGRLY+Q Sbjct 246 ELITITQYLRPSARHHPVERWVKPQEFVELKEEADEIGYAGVMSGPLVRSSYRAGRLYQQ 305 Query 302 ARNSRA 307 A + RA Sbjct 306 AIDQRA 311 >gi|256375478|ref|YP_003099138.1| lipoyl synthase [Actinosynnema mirum DSM 43827] gi|255919781|gb|ACU35292.1| lipoic acid synthetase [Actinosynnema mirum DSM 43827] Length=334 Score = 506 bits (1304), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 243/306 (80%), Positives = 269/306 (88%), Gaps = 0/306 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M+V EGR+LLRLEVRN+QTPIE+KP WIKTRA++GPEY +LK LV+REGLHTVCEEAGC Sbjct 1 MTVVPEGRKLLRLEVRNSQTPIEKKPSWIKTRAKMGPEYRDLKGLVKREGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGG+QCTRRCDFCQIDTGKPA+LDRDEPRRVA+SV+ MGLRY+TV Sbjct 61 PNIYECWEDREATFLIGGEQCTRRCDFCQIDTGKPADLDRDEPRRVAESVQAMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDL DGGAWLYA TVR I LNP TGVELLIPDFN P +LAEVF+S PEVLAHN Sbjct 121 TGVARDDLADGGAWLYAETVRQIHALNPGTGVELLIPDFNAVPEQLAEVFDSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 +ETVPRIFKRIRPAF Y RSL V+T AR+AGLVTKSNLILG+GET +EV AL DL AG Sbjct 181 LETVPRIFKRIRPAFRYERSLEVITRAREAGLVTKSNLILGMGETPEEVAEALRDLHAAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 C+I+TITQYLRPS RHHPVERWVKPEEF+ AE LGF+GV+AGPLVRSSYRAGRLY Sbjct 241 CEIITITQYLRPSPRHHPVERWVKPEEFLVHKETAEELGFSGVMAGPLVRSSYRAGRLYA 300 Query 301 QARNSR 306 QA R Sbjct 301 QAVTKR 306 >gi|257055093|ref|YP_003132925.1| lipoyl synthase [Saccharomonospora viridis DSM 43017] gi|256584965|gb|ACU96098.1| lipoate synthase [Saccharomonospora viridis DSM 43017] Length=333 Score = 505 bits (1300), Expect = 4e-141, Method: Compositional matrix adjust. Identities = 240/305 (79%), Positives = 266/305 (88%), Gaps = 0/305 (0%) Query 3 VAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPN 62 + EGR+LLRLEVRN+QTPIE+KP WIKTRAR+GPE+TELK LVRREGLHTVCEEAGCPN Sbjct 1 MVPEGRKLLRLEVRNSQTPIEKKPSWIKTRARMGPEFTELKGLVRREGLHTVCEEAGCPN 60 Query 63 IFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTG 122 I+ECWEDREATFLIGGDQCTRRCDFCQIDTGKPAE DRDEPRRVA+SVR MGLRY+TVTG Sbjct 61 IYECWEDREATFLIGGDQCTRRCDFCQIDTGKPAEFDRDEPRRVAESVRAMGLRYSTVTG 120 Query 123 VARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVE 182 VARDDLPDGGAWLYA TVR I LNP TGVELLIPDFN +LAEVF S PEVLAHN+E Sbjct 121 VARDDLPDGGAWLYAETVRQIHALNPGTGVELLIPDFNANEEQLAEVFGSEPEVLAHNLE 180 Query 183 TVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCD 242 TVPRIFKRIRP F Y RSL V+ AR+AGLVTKSNLILG+GET +EV + DL +AGC+ Sbjct 181 TVPRIFKRIRPGFRYERSLEVIRKAREAGLVTKSNLILGMGETPEEVEPTMRDLVEAGCE 240 Query 243 IVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQA 302 I+TITQYLRPS RHHPV+RWVKPEEFV+ R A+ LGFAGV+AGPLVRSSYRAG+L+ Q Sbjct 241 ILTITQYLRPSVRHHPVDRWVKPEEFVEHTRVAKKLGFAGVMAGPLVRSSYRAGKLFAQT 300 Query 303 RNSRA 307 + R Sbjct 301 KQHRG 305 >gi|262202969|ref|YP_003274177.1| lipoic acid synthetase [Gordonia bronchialis DSM 43247] gi|262086316|gb|ACY22284.1| lipoic acid synthetase [Gordonia bronchialis DSM 43247] Length=342 Score = 504 bits (1299), Expect = 6e-141, Method: Compositional matrix adjust. Identities = 245/309 (80%), Positives = 273/309 (89%), Gaps = 2/309 (0%) Query 3 VAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPN 62 A +GR+LLRLEVRNAQTPIERKP WI+TRA +GPE+TELK LV+REGLHTVCEEAGCPN Sbjct 9 TAPDGRKLLRLEVRNAQTPIERKPEWIRTRATMGPEFTELKGLVKREGLHTVCEEAGCPN 68 Query 63 IFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTG 122 I+ECWEDREATFLIGG+QCTRRCDFCQIDTG+PA LDRDEPRRVA+SV+ MGLRY+T+TG Sbjct 69 IYECWEDREATFLIGGEQCTRRCDFCQIDTGRPAPLDRDEPRRVAESVQAMGLRYSTITG 128 Query 123 VARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVE 182 VARDDLPD GAWLYA TVRAI LNP TGVE LIPDF+ +P LAEVF++ PEVLAHN+E Sbjct 129 VARDDLPDEGAWLYAETVRAIHRLNPGTGVENLIPDFHAKPDLLAEVFDARPEVLAHNLE 188 Query 183 TVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCD 242 TVPRIFKRIRPAF Y RSL VLTAARD GLVTKSNLILG+GET EV++A+ DL +AGCD Sbjct 189 TVPRIFKRIRPAFRYERSLEVLTAARDFGLVTKSNLILGMGETPREVQSAIVDLHEAGCD 248 Query 243 IVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQ- 301 I+TITQYLRPS RHHPVERWVKPEEFV + FA +GFAGV+AGPLVRSSYRAGRLY Q Sbjct 249 ILTITQYLRPSPRHHPVERWVKPEEFVDHSEFANEVGFAGVMAGPLVRSSYRAGRLYAQA 308 Query 302 -ARNSRALA 309 AR+ R LA Sbjct 309 MARHGRELA 317 >gi|326330114|ref|ZP_08196425.1| lipoyl synthase [Nocardioidaceae bacterium Broad-1] gi|325951927|gb|EGD43956.1| lipoyl synthase [Nocardioidaceae bacterium Broad-1] Length=320 Score = 504 bits (1297), Expect = 8e-141, Method: Compositional matrix adjust. Identities = 240/303 (80%), Positives = 265/303 (88%), Gaps = 0/303 (0%) Query 4 AAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNI 63 A EGR+LLRLEVRNAQTPIERKP WIKT+A++GPEY EL LV+ EGLHTVC+EAGCPNI Sbjct 6 APEGRKLLRLEVRNAQTPIERKPEWIKTKAKMGPEYKELTALVKSEGLHTVCQEAGCPNI 65 Query 64 FECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGV 123 FECWEDREATFLIGGDQCTRRCDFCQIDTGKP +LDRDEPRRVA+SV+TMGL+YAT+TGV Sbjct 66 FECWEDREATFLIGGDQCTRRCDFCQIDTGKPTDLDRDEPRRVAESVQTMGLKYATITGV 125 Query 124 ARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVET 183 ARDDL DGGAWLYA TV+ I ELNP TGVE LIPDFNG P L EVFES PEVLAHNVET Sbjct 126 ARDDLADGGAWLYAETVKQIHELNPETGVENLIPDFNGIPELLEEVFESRPEVLAHNVET 185 Query 184 VPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDI 243 VPRIFKRIRPAF Y RSL V+T ARD GLVTKSNLILG+GET +EV AL DL AGC++ Sbjct 186 VPRIFKRIRPAFRYERSLDVITQARDFGLVTKSNLILGMGETREEVSEALRDLHAAGCEL 245 Query 244 VTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQAR 303 +TITQYLRPS RHHPVERWVKPEEF++ AE +GF+GV++GPLVRSSYRAGRLY QA Sbjct 246 ITITQYLRPSVRHHPVERWVKPEEFIELQAEAEEIGFSGVMSGPLVRSSYRAGRLYRQAI 305 Query 304 NSR 306 +R Sbjct 306 EAR 308 >gi|334337346|ref|YP_004542498.1| Lipoyl synthase [Isoptericola variabilis 225] gi|334107714|gb|AEG44604.1| Lipoyl synthase [Isoptericola variabilis 225] Length=336 Score = 503 bits (1296), Expect = 1e-140, Method: Compositional matrix adjust. Identities = 243/309 (79%), Positives = 266/309 (87%), Gaps = 0/309 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M++A EGRR+LR+E RNA+TPIE+KP WIKTRA +GPEY ELK LVR EGLHTVCEEAGC Sbjct 1 MTIAPEGRRMLRIEARNAETPIEKKPEWIKTRAVMGPEYKELKGLVRGEGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPA+ D DEPRRVA+SVR MGLRY+TV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPADFDADEPRRVAESVRAMGLRYSTV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDL DGGAWLYA TVR I LNP TGVELLIPDFN P L EV ES PEVLAHN Sbjct 121 TGVARDDLADGGAWLYAETVRQIHALNPGTGVELLIPDFNAIPELLDEVNESRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFK+IRPAF Y RSL VLT AR+AGLVTKSNLILG+GET DEV+ AL DL AG Sbjct 181 VETVPRIFKQIRPAFRYERSLSVLTRAREAGLVTKSNLILGMGETIDEVKQALVDLHAAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CD++TITQYLRPS RHHPVERWV+PEEFV+ + +AE +GF GV+AGPLVRSSYRAGRL+ Sbjct 241 CDLITITQYLRPSVRHHPVERWVRPEEFVELSEYAEEIGFLGVMAGPLVRSSYRAGRLWG 300 Query 301 QARNSRALA 309 QA R A Sbjct 301 QAMTKRGRA 309 >gi|296139233|ref|YP_003646476.1| lipoic acid synthetase [Tsukamurella paurometabola DSM 20162] gi|296027367|gb|ADG78137.1| lipoic acid synthetase [Tsukamurella paurometabola DSM 20162] Length=341 Score = 502 bits (1292), Expect = 4e-140, Method: Compositional matrix adjust. Identities = 237/295 (81%), Positives = 264/295 (90%), Gaps = 0/295 (0%) Query 8 RRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNIFECW 67 R+LLRLEVRNAQTPIERKP WI+TRA++GPE+TELK LV+REGLHTVCEEAGCPNI+ECW Sbjct 11 RKLLRLEVRNAQTPIERKPNWIRTRAKMGPEFTELKGLVKREGLHTVCEEAGCPNIYECW 70 Query 68 EDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGVARDD 127 EDREATFLIGG+QCTRRCDFCQIDTGKPAELDRDEPRRVA+SV+ MGLRY+T+TGVARDD Sbjct 71 EDREATFLIGGEQCTRRCDFCQIDTGKPAELDRDEPRRVAESVQAMGLRYSTITGVARDD 130 Query 128 LPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVETVPRI 187 LPD G WLYA TVR I LNP+TGVE LIPDF+ +P LAEVFES PEVLAHN+ETVPRI Sbjct 131 LPDEGVWLYAETVRQIHRLNPNTGVENLIPDFHAKPELLAEVFESRPEVLAHNLETVPRI 190 Query 188 FKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDIVTIT 247 FKRIRPAF Y RSL V+ ARD GLVTKSNLILG+GET +EV A+ DL DAGCDI+TIT Sbjct 191 FKRIRPAFRYERSLDVIRQARDFGLVTKSNLILGMGETPEEVTEAMHDLHDAGCDIITIT 250 Query 248 QYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQA 302 QYLRPS RHHPVERWVKPEEFV+ + AE +GFAGV+AGPLVRSSYRAG+LY +A Sbjct 251 QYLRPSPRHHPVERWVKPEEFVEHTQAAEEMGFAGVMAGPLVRSSYRAGKLYAKA 305 >gi|284030610|ref|YP_003380541.1| lipoic acid synthetase [Kribbella flavida DSM 17836] gi|283809903|gb|ADB31742.1| lipoic acid synthetase [Kribbella flavida DSM 17836] Length=321 Score = 501 bits (1289), Expect = 7e-140, Method: Compositional matrix adjust. Identities = 238/311 (77%), Positives = 265/311 (86%), Gaps = 0/311 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M++A EGR+LLRLEVRNA+TPIERKP WIKTRA++GPEY +L+ LV+ E LHTVC+EAGC Sbjct 1 MTIAPEGRKLLRLEVRNAETPIERKPEWIKTRAKMGPEYQKLQALVKSEELHTVCQEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKP LDRDEPRRVA+SV MGLRYATV Sbjct 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPQALDRDEPRRVAESVTKMGLRYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDL DGGAWLYA T+R I LNP TGVE+L PDFN P +LAEVF S PEV AHN Sbjct 121 TGVARDDLEDGGAWLYAETIRQIHALNPGTGVEMLAPDFNAVPEQLAEVFSSRPEVFAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIF+RIRP F Y RSL V+T ARD GLVTKSNLILG+GET +EV AL DL AG Sbjct 181 VETVPRIFRRIRPGFRYERSLDVITQARDYGLVTKSNLILGMGETREEVSQALADLHAAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 C+I+TITQYLRPS RHHPVERWV+PEEFV+ AE +GFAGV++GPLVRSSYRAGRLY Sbjct 241 CEIITITQYLRPSVRHHPVERWVRPEEFVELQAEAEQIGFAGVMSGPLVRSSYRAGRLYR 300 Query 301 QARNSRALASR 311 QA SR A++ Sbjct 301 QAVESRTTAAQ 311 >gi|297161185|gb|ADI10897.1| lipoyl synthase [Streptomyces bingchenggensis BCW-1] Length=316 Score = 500 bits (1288), Expect = 9e-140, Method: Compositional matrix adjust. Identities = 235/308 (77%), Positives = 268/308 (88%), Gaps = 0/308 (0%) Query 2 SVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCP 61 +VA +GR++LRLEVRN+QTPIERKP WIKTRA++GPEYTEL+ LV+REGLHTVC+EAGCP Sbjct 3 AVAPDGRKMLRLEVRNSQTPIERKPEWIKTRAKMGPEYTELQGLVKREGLHTVCQEAGCP 62 Query 62 NIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVT 121 NI+ECWEDREATFLIGGDQCTRRCDFCQIDTGKP LDRDEPRRVA+SV++M L+YATVT Sbjct 63 NIYECWEDREATFLIGGDQCTRRCDFCQIDTGKPQALDRDEPRRVAESVQSMELKYATVT 122 Query 122 GVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNV 181 GVARDDL DGGAWLYA TVR I L P TGVELLIPDFN P +LAEVF + PEVLAHNV Sbjct 123 GVARDDLEDGGAWLYAETVRQIHSLMPDTGVELLIPDFNAVPEQLAEVFSARPEVLAHNV 182 Query 182 ETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGC 241 ETVPRIFKRIRP F Y RSL V+T AR+AGLVTKSNLILG+GE E+ AL DL DAGC Sbjct 183 ETVPRIFKRIRPGFRYERSLEVITKAREAGLVTKSNLILGMGEERAEISQALQDLYDAGC 242 Query 242 DIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQ 301 +++TITQYLRPS RHHPV+RWVKP+EFV+ AE +G+AGV++GPLVRSSYRAGRLY+Q Sbjct 243 ELITITQYLRPSVRHHPVDRWVKPQEFVELKEEAEEIGYAGVMSGPLVRSSYRAGRLYQQ 302 Query 302 ARNSRALA 309 A R +A Sbjct 303 AIEKRGIA 310 >gi|133910832|emb|CAM00945.1| putative lipoic acid synthetase [Saccharopolyspora erythraea NRRL 2338] Length=323 Score = 499 bits (1286), Expect = 2e-139, Method: Compositional matrix adjust. Identities = 241/298 (81%), Positives = 263/298 (89%), Gaps = 0/298 (0%) Query 11 LRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNIFECWEDR 70 +RLEVRN+QTPIE+KP WIKTRAR+GPEY ELK LV+REGLHTVCEEAGCPNIFECWEDR Sbjct 1 MRLEVRNSQTPIEKKPSWIKTRARMGPEYQELKGLVKREGLHTVCEEAGCPNIFECWEDR 60 Query 71 EATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGVARDDLPD 130 EATFLIGGDQCTRRCDFCQIDTGKPAELD +EPRRVA+SV+ MGLRY+TVTGVARDDL D Sbjct 61 EATFLIGGDQCTRRCDFCQIDTGKPAELDVEEPRRVAESVQAMGLRYSTVTGVARDDLED 120 Query 131 GGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVETVPRIFKR 190 GGAWLYA TVR I +LNP TGVELLIPDFN +P +LAEVF S PEVLAHNVETVPRIFKR Sbjct 121 GGAWLYAETVRQIHQLNPGTGVELLIPDFNADPGQLAEVFGSRPEVLAHNVETVPRIFKR 180 Query 191 IRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDIVTITQYL 250 IRPAF Y RSL V+T AR+ GLVTKSNLILG+GET +EV AL DLR+AG DI+TITQYL Sbjct 181 IRPAFRYERSLEVITRAREDGLVTKSNLILGMGETPEEVTEALRDLREAGTDIITITQYL 240 Query 251 RPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQARNSRAL 308 RPS RHHPVERWVKPEEFV+ R AE LGF GV+AGPLVRSSYRAGRLY +A R + Sbjct 241 RPSPRHHPVERWVKPEEFVEHTRTAEELGFPGVMAGPLVRSSYRAGRLYAKATEHRGM 298 >gi|312195619|ref|YP_004015680.1| lipoic acid synthetase [Frankia sp. EuI1c] gi|311226955|gb|ADP79810.1| lipoic acid synthetase [Frankia sp. EuI1c] Length=317 Score = 498 bits (1282), Expect = 5e-139, Method: Compositional matrix adjust. Identities = 239/304 (79%), Positives = 267/304 (88%), Gaps = 0/304 (0%) Query 4 AAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGCPNI 63 AAEGR LLRLE RNA TPIERKPPWI+TR R GPEYT++KNLVR EGLHTVCEEAGCPNI Sbjct 7 AAEGRPLLRLEARNAATPIERKPPWIRTRLRTGPEYTDIKNLVRAEGLHTVCEEAGCPNI 66 Query 64 FECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATVTGV 123 +ECWEDREATFLIGGD CTRRCDFCQIDTG+P LD DEPRRVA+SV TMGLRYAT+TGV Sbjct 67 YECWEDREATFLIGGDVCTRRCDFCQIDTGRPTPLDVDEPRRVAESVATMGLRYATITGV 126 Query 124 ARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHNVET 183 ARDDLPDGG+WLYA TVRA+ +P TGVE+LIPDF G+P +LAEVF++ PEVLAHN+ET Sbjct 127 ARDDLPDGGSWLYAETVRAVHAGSPGTGVEVLIPDFGGQPDQLAEVFDAAPEVLAHNLET 186 Query 184 VPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAGCDI 243 VPRIFKRIRPAF Y RSL VLTAAR AGLVTKSNLILGLGET E+ TA+ DL AGCD+ Sbjct 187 VPRIFKRIRPAFRYERSLQVLTAARAAGLVTKSNLILGLGETDAEIETAMTDLHAAGCDL 246 Query 244 VTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYEQAR 303 +T+TQYLRP+ RHHPVERWV+PEEFV +A E +GFAGVLAGPLVRSSYRAGRLY+QA Sbjct 247 LTVTQYLRPTPRHHPVERWVRPEEFVAWAERGEQIGFAGVLAGPLVRSSYRAGRLYQQAI 306 Query 304 NSRA 307 +R+ Sbjct 307 AARS 310 >gi|269956823|ref|YP_003326612.1| lipoic acid synthetase [Xylanimonas cellulosilytica DSM 15894] gi|269305504|gb|ACZ31054.1| lipoic acid synthetase [Xylanimonas cellulosilytica DSM 15894] Length=333 Score = 498 bits (1282), Expect = 5e-139, Method: Compositional matrix adjust. Identities = 234/308 (76%), Positives = 270/308 (88%), Gaps = 0/308 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M++A EGRR+LR+E RNA+TPIE+KP WI+T+A +GPEY ++K LV+ LHTVCEEAGC Sbjct 1 MTIAPEGRRMLRIEARNAETPIEKKPEWIRTKATMGPEYRDMKKLVQGGNLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNIFECWEDREATFLIGG+QCTRRCDFCQIDTGKPA LDRDEPRRVA+SV+ MGL+Y+T+ Sbjct 61 PNIFECWEDREATFLIGGEQCTRRCDFCQIDTGKPAALDRDEPRRVAESVQQMGLKYSTI 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDLPDGGAWLYA TVR I ELNP+TGVE LIPDFNG P L EVF+S PEVLAHN Sbjct 121 TGVARDDLPDGGAWLYAETVRQIHELNPATGVENLIPDFNGIPELLDEVFDSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 +ETVPRIFK+IRPAF Y RSL VL+ AR AGLVTKSNLILG+GET DEV+ AL DL DAG Sbjct 181 LETVPRIFKQIRPAFRYDRSLDVLSRARAAGLVTKSNLILGMGETIDEVKQALVDLHDAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CD++TITQYLRPS RHHP+ERWV+PEEFV+ ++FAE GF GV+AGPLVRSSYRAGRL+ Sbjct 241 CDLITITQYLRPSVRHHPIERWVRPEEFVELSQFAEETGFLGVMAGPLVRSSYRAGRLWG 300 Query 301 QARNSRAL 308 QA + R + Sbjct 301 QAMSKRGI 308 >gi|152967232|ref|YP_001363016.1| lipoyl synthase [Kineococcus radiotolerans SRS30216] gi|189046606|sp|A6WD63.1|LIPA_KINRD RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|151361749|gb|ABS04752.1| lipoic acid synthetase [Kineococcus radiotolerans SRS30216] Length=333 Score = 498 bits (1282), Expect = 5e-139, Method: Compositional matrix adjust. Identities = 234/309 (76%), Positives = 267/309 (87%), Gaps = 0/309 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 M++A EGRR+LR+E RNA+TPIERKP WI+T+AR GP+YTELK LV+ GLHTVCEEAGC Sbjct 1 MTIAPEGRRMLRIEARNAETPIERKPSWIRTKARTGPDYTELKGLVKSGGLHTVCEEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGG +CTRRCDFCQIDTGKP+ LDRDEPRRVA+S+ TMGLRYAT+ Sbjct 61 PNIYECWEDREATFLIGGSECTRRCDFCQIDTGKPSPLDRDEPRRVAESIATMGLRYATI 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDL DGGAWLYA T+RA NP TGVE+L+PDFNG+P L +VF++ PEV AHN Sbjct 121 TGVARDDLDDGGAWLYAETIRATHAANPGTGVEILVPDFNGKPELLQQVFDAQPEVFAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 VETVPRIFK IRPAF Y RSL V+T RDAGLVTKSNLILG+GET +EV AL DLR AG Sbjct 181 VETVPRIFKSIRPAFRYERSLDVITQGRDAGLVTKSNLILGMGETDEEVLEALADLRGAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CDI+TITQYLRP+ RHHPVERWVKPE+FV+F+ AE LGFAGV+AGPLVRSSYRAGRL+ Sbjct 241 CDIITITQYLRPTPRHHPVERWVKPEKFVEFSAEAERLGFAGVMAGPLVRSSYRAGRLWA 300 Query 301 QARNSRALA 309 QA R +A Sbjct 301 QAMKRRGVA 309 >gi|72161395|ref|YP_289052.1| lipoyl synthase [Thermobifida fusca YX] gi|123774746|sp|Q47R88.1|LIPA_THEFY RecName: Full=Lipoyl synthase; AltName: Full=Lip-syn; Short=LS; AltName: Full=Lipoate synthase; AltName: Full=Lipoic acid synthase; AltName: Full=Sulfur insertion protein lipA gi|71915127|gb|AAZ55029.1| lipoate synthase [Thermobifida fusca YX] Length=312 Score = 497 bits (1280), Expect = 8e-139, Method: Compositional matrix adjust. Identities = 238/306 (78%), Positives = 265/306 (87%), Gaps = 0/306 (0%) Query 1 MSVAAEGRRLLRLEVRNAQTPIERKPPWIKTRARIGPEYTELKNLVRREGLHTVCEEAGC 60 MS+A EGRRLLR+E RN+ TPIE+KPPWIK RA++G EYTEL LV+REGLHTVC+EAGC Sbjct 1 MSIAPEGRRLLRIEARNSTTPIEKKPPWIKIRAKMGSEYTELHALVKREGLHTVCQEAGC 60 Query 61 PNIFECWEDREATFLIGGDQCTRRCDFCQIDTGKPAELDRDEPRRVADSVRTMGLRYATV 120 PNI+ECWEDREATFLIGGDQCTRRCDFCQI TGKPA LDR EP RVA+SVRTMGL+YATV Sbjct 61 PNIYECWEDREATFLIGGDQCTRRCDFCQIATGKPAALDRGEPLRVAESVRTMGLKYATV 120 Query 121 TGVARDDLPDGGAWLYAATVRAIKELNPSTGVELLIPDFNGEPTRLAEVFESGPEVLAHN 180 TGVARDDL DGGAWLYA TVR I ELNP TGVELLIPDFN +P LAEVF S PEVLAHN Sbjct 121 TGVARDDLDDGGAWLYAETVRKIHELNPGTGVELLIPDFNADPDLLAEVFSSRPEVLAHN 180 Query 181 VETVPRIFKRIRPAFTYRRSLGVLTAARDAGLVTKSNLILGLGETSDEVRTALGDLRDAG 240 +ETVPRIFKRIRP F Y RSL V+T AR+AGLVTKSNLILG+GET +E+ A+ DL +AG Sbjct 181 IETVPRIFKRIRPGFRYERSLEVITRAREAGLVTKSNLILGMGETREEISQAMRDLYEAG 240 Query 241 CDIVTITQYLRPSARHHPVERWVKPEEFVQFARFAEGLGFAGVLAGPLVRSSYRAGRLYE 300 CD++TITQYLRPS HHPV+RWVKPEEFV+ R AE +GFAGV++GPLVRSSYRAGRLY Sbjct 241 CDLLTITQYLRPSRLHHPVDRWVKPEEFVELGREAEEIGFAGVMSGPLVRSSYRAGRLYR 300 Query 301 QARNSR 306 QA R Sbjct 301 QAIERR 306 Lambda K H 0.321 0.138 0.417 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 533708119992 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40