BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2241 Length=901 Score E Sequences producing significant alignments: (Bits) Value gi|253798691|ref|YP_003031692.1| pyruvate dehydrogenase E1 compo... 1858 0.0 gi|254551285|ref|ZP_05141732.1| pyruvate dehydrogenase subunit E... 1857 0.0 gi|298525733|ref|ZP_07013142.1| pyruvate dehydrogenase subunit E... 1857 0.0 gi|15841734|ref|NP_336771.1| pyruvate dehydrogenase subunit E1 [... 1857 0.0 gi|289574930|ref|ZP_06455157.1| pyruvate dehydrogenase E1 compon... 1856 0.0 gi|344220063|gb|AEN00694.1| pyruvate dehydrogenase subunit E1 [M... 1855 0.0 gi|31793421|ref|NP_855914.1| pyruvate dehydrogenase subunit E1 [... 1853 0.0 gi|118465251|ref|YP_881405.1| pyruvate dehydrogenase subunit E1 ... 1738 0.0 gi|41408092|ref|NP_960928.1| pyruvate dehydrogenase subunit E1 [... 1736 0.0 gi|254819066|ref|ZP_05224067.1| pyruvate dehydrogenase subunit E... 1735 0.0 gi|342857266|ref|ZP_08713922.1| pyruvate dehydrogenase subunit E... 1734 0.0 gi|336461854|gb|EGO40710.1| pyruvate dehydrogenase E1 component,... 1733 0.0 gi|296166132|ref|ZP_06848577.1| pyruvate decarboxylase, E1 compo... 1730 0.0 gi|183983324|ref|YP_001851615.1| pyruvate dehydrogenase E1 compo... 1692 0.0 gi|118617007|ref|YP_905339.1| pyruvate dehydrogenase subunit E1 ... 1689 0.0 gi|289762405|ref|ZP_06521783.1| pyruvate dehydrogenase subunit E... 1672 0.0 gi|15827869|ref|NP_302132.1| pyruvate dehydrogenase subunit E1 [... 1667 0.0 gi|3150233|emb|CAA19205.1| pyruvate dehydrogenase e1 component [... 1665 0.0 gi|315443827|ref|YP_004076706.1| pyruvate dehydrogenase E1 compo... 1659 0.0 gi|120404711|ref|YP_954540.1| pyruvate dehydrogenase subunit E1 ... 1658 0.0 gi|145223368|ref|YP_001134046.1| pyruvate dehydrogenase subunit ... 1658 0.0 gi|240170076|ref|ZP_04748735.1| pyruvate dehydrogenase subunit E... 1656 0.0 gi|119869456|ref|YP_939408.1| pyruvate dehydrogenase subunit E1 ... 1650 0.0 gi|108800328|ref|YP_640525.1| pyruvate dehydrogenase subunit E1 ... 1648 0.0 gi|118470577|ref|YP_888598.1| pyruvate dehydrogenase subunit E1 ... 1626 0.0 gi|289750838|ref|ZP_06510216.1| pyruvate dehydrogenase subunit E... 1625 0.0 gi|333990294|ref|YP_004522908.1| pyruvate dehydrogenase E1 compo... 1603 0.0 gi|169628972|ref|YP_001702621.1| pyruvate dehydrogenase subunit ... 1587 0.0 gi|325676998|ref|ZP_08156669.1| pyruvate decarboxylase, E1 compo... 1498 0.0 gi|312140255|ref|YP_004007591.1| pyruvate dehydrogenase acee [Rh... 1497 0.0 gi|226360334|ref|YP_002778112.1| pyruvate dehydrogenase subunit ... 1490 0.0 gi|226307157|ref|YP_002767117.1| pyruvate dehydrogenase E1 compo... 1488 0.0 gi|226361706|ref|YP_002779484.1| 2-oxoacid dehydrogenase subunit... 1487 0.0 gi|229490290|ref|ZP_04384132.1| pyruvate dehydrogenase (acetyl-t... 1486 0.0 gi|111018209|ref|YP_701181.1| pyruvate dehydrogenase subunit E1 ... 1484 0.0 gi|333918898|ref|YP_004492479.1| pyruvate dehydrogenase E1 compo... 1484 0.0 gi|54023581|ref|YP_117823.1| pyruvate dehydrogenase subunit E1 [... 1483 0.0 gi|343924115|ref|ZP_08763678.1| pyruvate dehydrogenase E1 compon... 1473 0.0 gi|111019557|ref|YP_702529.1| 2-oxoacid dehydrogenase subunit E1... 1468 0.0 gi|296140416|ref|YP_003647659.1| 2-oxo-acid dehydrogenase E1 sub... 1446 0.0 gi|257055083|ref|YP_003132915.1| pyruvate dehydrogenase subunit ... 1434 0.0 gi|331695979|ref|YP_004332218.1| 2-oxo-acid dehydrogenase E1 sub... 1422 0.0 gi|262203010|ref|YP_003274218.1| 2-oxo-acid dehydrogenase E1 sub... 1418 0.0 gi|326382458|ref|ZP_08204149.1| pyruvate dehydrogenase subunit E... 1416 0.0 gi|256375471|ref|YP_003099131.1| pyruvate dehydrogenase subunit ... 1409 0.0 gi|302525298|ref|ZP_07277640.1| pyruvate dehydrogenase [Streptom... 1406 0.0 gi|300784030|ref|YP_003764321.1| pyruvate dehydrogenase E1 compo... 1402 0.0 gi|317509071|ref|ZP_07966700.1| pyruvate dehydrogenase [Segnilip... 1402 0.0 gi|291007423|ref|ZP_06565396.1| pyruvate dehydrogenase subunit E... 1400 0.0 gi|134098118|ref|YP_001103779.1| pyruvate dehydrogenase subunit ... 1400 0.0 >gi|253798691|ref|YP_003031692.1| pyruvate dehydrogenase E1 component aceE [Mycobacterium tuberculosis KZN 1435] gi|297634836|ref|ZP_06952616.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis KZN 4207] gi|297731827|ref|ZP_06960945.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis KZN R506] 24 more sequence titles Length=930 Score = 1858 bits (4813), Expect = 0.0, Method: Compositional matrix adjust. Identities = 901/901 (100%), Positives = 901/901 (100%), Gaps = 0/901 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE Sbjct 390 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP Sbjct 450 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY Sbjct 690 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET Sbjct 750 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD Sbjct 810 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG Sbjct 870 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 929 Query 901 A 901 A Sbjct 930 A 930 >gi|254551285|ref|ZP_05141732.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=930 Score = 1857 bits (4811), Expect = 0.0, Method: Compositional matrix adjust. Identities = 900/901 (99%), Positives = 900/901 (99%), Gaps = 0/901 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPG GDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH Sbjct 150 NHFFRGKSHPGSGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE Sbjct 390 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP Sbjct 450 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY Sbjct 690 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET Sbjct 750 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD Sbjct 810 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG Sbjct 870 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 929 Query 901 A 901 A Sbjct 930 A 930 >gi|298525733|ref|ZP_07013142.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis 94_M4241A] gi|298495527|gb|EFI30821.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis 94_M4241A] Length=906 Score = 1857 bits (4811), Expect = 0.0, Method: Compositional matrix adjust. Identities = 901/901 (100%), Positives = 901/901 (100%), Gaps = 0/901 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 6 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 65 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 66 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 125 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH Sbjct 126 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 185 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 186 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 245 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 246 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 305 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL Sbjct 306 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 365 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE Sbjct 366 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 425 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP Sbjct 426 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 485 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL Sbjct 486 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 545 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 546 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 605 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 606 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 665 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY Sbjct 666 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 725 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET Sbjct 726 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 785 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD Sbjct 786 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 845 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG Sbjct 846 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 905 Query 901 A 901 A Sbjct 906 A 906 >gi|15841734|ref|NP_336771.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis CDC1551] gi|121638123|ref|YP_978347.1| pyruvate dehydrogenase subunit E1 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|148662062|ref|YP_001283585.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis H37Ra] 32 more sequence titles Length=901 Score = 1857 bits (4809), Expect = 0.0, Method: Compositional matrix adjust. Identities = 900/901 (99%), Positives = 901/901 (100%), Gaps = 0/901 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +ASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 1 MASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH Sbjct 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL Sbjct 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE Sbjct 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP Sbjct 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL Sbjct 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY Sbjct 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET Sbjct 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD Sbjct 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG Sbjct 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 Query 901 A 901 A Sbjct 901 A 901 >gi|289574930|ref|ZP_06455157.1| pyruvate dehydrogenase E1 component aceE [Mycobacterium tuberculosis K85] gi|339632267|ref|YP_004723909.1| pyruvate dehydrogenase subunit E1 [Mycobacterium africanum GM041182] gi|289539361|gb|EFD43939.1| pyruvate dehydrogenase E1 component aceE [Mycobacterium tuberculosis K85] gi|339331623|emb|CCC27322.1| putative pyruvate dehydrogenase E1 component aceE (pyruvate decarboxylase) [Mycobacterium africanum GM041182] Length=901 Score = 1856 bits (4808), Expect = 0.0, Method: Compositional matrix adjust. Identities = 899/901 (99%), Positives = 900/901 (99%), Gaps = 0/901 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +ASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 1 MASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH Sbjct 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL Sbjct 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE Sbjct 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP Sbjct 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL Sbjct 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY Sbjct 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGV IET Sbjct 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVTIET 780 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD Sbjct 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG Sbjct 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 Query 901 A 901 A Sbjct 901 A 901 >gi|344220063|gb|AEN00694.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis CTRI-2] Length=901 Score = 1855 bits (4805), Expect = 0.0, Method: Compositional matrix adjust. Identities = 899/901 (99%), Positives = 900/901 (99%), Gaps = 0/901 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +ASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 1 MASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH Sbjct 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL Sbjct 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE Sbjct 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRDTQRIPVSDAQLEENPYLPPYYHPGLN PEIRYMLDRRRALGGFVPERRTKSKALTLP Sbjct 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNRPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL Sbjct 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY Sbjct 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET Sbjct 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD Sbjct 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG Sbjct 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 Query 901 A 901 A Sbjct 901 A 901 >gi|31793421|ref|NP_855914.1| pyruvate dehydrogenase subunit E1 [Mycobacterium bovis AF2122/97] gi|31619013|emb|CAD97118.1| Probable pyruvate dehydrogenase E1 component aceE (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE) [Mycobacterium bovis AF2122/97] Length=901 Score = 1853 bits (4799), Expect = 0.0, Method: Compositional matrix adjust. Identities = 899/901 (99%), Positives = 900/901 (99%), Gaps = 0/901 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +ASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 1 MASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH Sbjct 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRD ALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL Sbjct 301 ALLHADRDRALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE Sbjct 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP Sbjct 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL Sbjct 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY Sbjct 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET Sbjct 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD Sbjct 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG Sbjct 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPGPG 900 Query 901 A 901 A Sbjct 901 A 901 >gi|118465251|ref|YP_881405.1| pyruvate dehydrogenase subunit E1 [Mycobacterium avium 104] gi|254774906|ref|ZP_05216422.1| pyruvate dehydrogenase subunit E1 [Mycobacterium avium subsp. avium ATCC 25291] gi|118166538|gb|ABK67435.1| pyruvate dehydrogenase E1 component [Mycobacterium avium 104] Length=929 Score = 1738 bits (4500), Expect = 0.0, Method: Compositional matrix adjust. Identities = 834/898 (93%), Positives = 864/898 (97%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFD LL+R GPSRARYLMLRLLERAGEQRVAIP+LTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDELLERSGPSRARYLMLRLLERAGEQRVAIPSLTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQ+FIQGHASPGIYARAFLEGRLTA+QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQIFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHAGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL V A E LDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLIQVAANEALDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDG YVRDHFFGRDPRTKALVENM+D +IWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVENMTDAEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGY+LG HF+GRNATHQMKKL LEDLK Sbjct 390 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLKH 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD RIP+SDAQL+ENPYLPPYYHPG +APEIRYMLDRRR LGGF+PERRTK+KAL LP Sbjct 450 FRDAMRIPISDAQLDENPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERRTKAKALRLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYA LKKGSG QEVATTMATVRTFKEVLRDK+IGPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRDIYAALKKGSGTQEVATTMATVRTFKEVLRDKEIGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDA+LMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDAELMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQM RGF+LGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDGLWAAADQMTRGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARM GENPE+++FYITVYNEPYVQPPEPENFDPEG+LRG+Y Sbjct 690 VAYDPAFAYEIAYIVESGLARMFGENPEDVYFYITVYNEPYVQPPEPENFDPEGLLRGLY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYH ATEQR NKAQILASGVAMP+AL AA+MLA EWDVAADVWSVTSWGELNRDGVAI+ Sbjct 750 RYHVATEQRANKAQILASGVAMPSALSAAKMLADEWDVAADVWSVTSWGELNRDGVAIDR 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 +LRHPDRPAGVPYVT+AL +A GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 ARLRHPDRPAGVPYVTQALSDASGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRYFNTDAESQVVAVLEALA DGEIDPSVPVAAARQYRIDDV AAPEQT+DPG Sbjct 870 TRPAARRYFNTDAESQVVAVLEALARDGEIDPSVPVAAARQYRIDDVLAAPEQTSDPG 927 >gi|41408092|ref|NP_960928.1| pyruvate dehydrogenase subunit E1 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396447|gb|AAS04311.1| AceE [Mycobacterium avium subsp. paratuberculosis K-10] Length=929 Score = 1736 bits (4497), Expect = 0.0, Method: Compositional matrix adjust. Identities = 833/898 (93%), Positives = 864/898 (97%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFD LL+R GPSRARYLMLRLLERAGEQRVA+P+LTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDELLERSGPSRARYLMLRLLERAGEQRVALPSLTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQ+FIQGHASPGIYARAFLEGRLTA+QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQIFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHAGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL V A E LDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLIQVAANEALDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDG YVRDHFFGRDPRTKALVENM+D +IWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVENMTDAEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGY+LG HF+GRNATHQMKKL LEDLK Sbjct 390 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLKH 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD RIP+SDAQL+ENPYLPPYYHPG +APEIRYMLDRRR LGGF+PERRTK+KAL LP Sbjct 450 FRDAMRIPISDAQLDENPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERRTKAKALRLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYA LKKGSG QEVATTMATVRTFKEVLRDK+IGPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRDIYAALKKGSGTQEVATTMATVRTFKEVLRDKEIGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDA+LMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDAELMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQM RGF+LGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDGLWAAADQMTRGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARM GENPE+++FYITVYNEPYVQPPEPENFDPEG+LRG+Y Sbjct 690 VAYDPAFAYEIAYIVESGLARMFGENPEDVYFYITVYNEPYVQPPEPENFDPEGLLRGLY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYH ATEQR NKAQILASGVAMP+AL AA+MLA EWDVAADVWSVTSWGELNRDGVAI+ Sbjct 750 RYHVATEQRANKAQILASGVAMPSALNAAKMLADEWDVAADVWSVTSWGELNRDGVAIDR 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 +LRHPDRPAGVPYVT+AL +A GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 ARLRHPDRPAGVPYVTQALSDASGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRYFNTDAESQVVAVLEALA DGEIDPSVPVAAARQYRIDDV AAPEQT+DPG Sbjct 870 TRPAARRYFNTDAESQVVAVLEALARDGEIDPSVPVAAARQYRIDDVLAAPEQTSDPG 927 >gi|254819066|ref|ZP_05224067.1| pyruvate dehydrogenase subunit E1 [Mycobacterium intracellulare ATCC 13950] Length=929 Score = 1735 bits (4493), Expect = 0.0, Method: Compositional matrix adjust. Identities = 829/898 (93%), Positives = 865/898 (97%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFD LL+R GPSRARYLMLRLLERAGEQRVAIP+LTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDELLERSGPSRARYLMLRLLERAGEQRVAIPSLTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLT +QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHPGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL HVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLLHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDG YVRDHFFGRDPRTKALV NMSD +IWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVANMSDSEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGY+LG HF+GRNATHQMKKL L+DLK+ Sbjct 390 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALQDLKD 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD RIP++DAQLEE+PYLPPY+HPG +APEIRYM+DRRR LGG++PERRTK+KAL LP Sbjct 450 FRDAMRIPINDAQLEEDPYLPPYFHPGSDAPEIRYMIDRRRTLGGYLPERRTKAKALRLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 RDIYA LKKGSG QEVATTMATVRTFKEVLRDK++GPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 SRDIYAALKKGSGTQEVATTMATVRTFKEVLRDKEVGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDADLMLAYKESEVG ILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDADLMLAYKESEVGHILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQM RGF+LGATAGRTTLTGEGLQHADGHSLLLA+TNPAV Sbjct 630 YIFYSMFGFQRTGDGLWAAADQMTRGFLLGATAGRTTLTGEGLQHADGHSLLLASTNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARM G++PEN+FFYITVYNEPYVQPPEP+NFDPEGVLRG+Y Sbjct 690 VAYDPAFAYEIAYIVESGLARMFGQDPENVFFYITVYNEPYVQPPEPDNFDPEGVLRGLY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYH ATEQR NKAQILASGVAMPAAL AA+MLAAEWDVAADVWSVTSWGELNRDGVA++ Sbjct 750 RYHVATEQRANKAQILASGVAMPAALDAAKMLAAEWDVAADVWSVTSWGELNRDGVAVDR 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 +LRHPDR AGVPYVT+AL +A GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 ARLRHPDRQAGVPYVTQALSDAVGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRYFNTDAESQVVAVLEALA DGEIDPSVPVAAARQYRIDDV AAPEQT+DPG Sbjct 870 TRPAARRYFNTDAESQVVAVLEALARDGEIDPSVPVAAARQYRIDDVQAAPEQTSDPG 927 >gi|342857266|ref|ZP_08713922.1| pyruvate dehydrogenase subunit E1 [Mycobacterium colombiense CECT 3035] gi|342134599|gb|EGT87765.1| pyruvate dehydrogenase subunit E1 [Mycobacterium colombiense CECT 3035] Length=929 Score = 1734 bits (4492), Expect = 0.0, Method: Compositional matrix adjust. Identities = 829/898 (93%), Positives = 866/898 (97%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFD LL+R GPSRARYLMLRLLERAGEQRVA+P+LTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDELLERSGPSRARYLMLRLLERAGEQRVALPSLTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGK+HPGGGDQVFIQGHASPGIYARAFLEGRLTA++LDGFRQEHSH GGLPSYPH Sbjct 150 NHFFRGKAHPGGGDQVFIQGHASPGIYARAFLEGRLTADRLDGFRQEHSHAAGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDG YVRDHFFGRDPRTKALV NM+D +IWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVANMTDAEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAA+DHKGQPTVILAKTIKGY+LG HF+GRNATHQMKKL LEDLK Sbjct 390 KRGGHDYRKVYAAYRAALDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLKR 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD+ RIP+SDAQL+ENPYLPPYYHPG +APEIRYMLDRRR LGGF+PERRTK+KAL LP Sbjct 450 FRDSMRIPISDAQLDENPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERRTKAKALRLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRD YA LKKGSG QEVATTMATVRTFKEVLRDK++GPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRDTYAALKKGSGTQEVATTMATVRTFKEVLRDKEVGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDA+LMLAYKESE G ILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDAELMLAYKESEAGHILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQM RGF+LGATAGRTTLTGEGLQHADGHSLLLA+TNPAV Sbjct 630 YIFYSMFGFQRTGDGLWAAADQMTRGFLLGATAGRTTLTGEGLQHADGHSLLLASTNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARM GENPE+I+FYIT+YNEPYVQPPEPENFDPEGVLRG+Y Sbjct 690 VAYDPAFAYEIAYIVESGLARMFGENPEDIYFYITIYNEPYVQPPEPENFDPEGVLRGLY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYH ATEQR +KAQILASGVAMPAAL AA+MLAAEWDVAADVWSVTSWGELNRDGVA++ Sbjct 750 RYHVATEQRASKAQILASGVAMPAALDAARMLAAEWDVAADVWSVTSWGELNRDGVAVDR 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 +LRHPDRPAGVPYVT+AL +A GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 TRLRHPDRPAGVPYVTQALSDAVGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRYFNTDAESQVVAVLEALA DGEIDPSVPVAAARQY+IDDV AAPEQT+DPG Sbjct 870 TRPAARRYFNTDAESQVVAVLEALARDGEIDPSVPVAAARQYKIDDVLAAPEQTSDPG 927 >gi|336461854|gb|EGO40710.1| pyruvate dehydrogenase E1 component, homodimeric type [Mycobacterium avium subsp. paratuberculosis S397] Length=929 Score = 1733 bits (4488), Expect = 0.0, Method: Compositional matrix adjust. Identities = 832/898 (93%), Positives = 863/898 (97%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFD LL+R GPSRARYLMLRLLERAGEQRVA+P+LTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDELLERSGPSRARYLMLRLLERAGEQRVALPSLTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQ+FIQGHASPGIYARAFLEGRLTA+QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQIFIQGHASPGIYARAFLEGRLTADQLDGFRQEHSHAGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL V A E LDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLIQVAANEALDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDG YQTYKANDG YVRDHFFGRDPRTKALVENM+D +IWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGVYQTYKANDGAYVRDHFFGRDPRTKALVENMTDAEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGY+LG HF+GRNATHQMKKL LEDLK Sbjct 390 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLKH 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD RIP+SDAQL+ENPYLPPYYHPG +APEIRYMLDRRR LGGF+PERRTK+KAL LP Sbjct 450 FRDAMRIPISDAQLDENPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERRTKAKALRLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYA LKKGSG QEVATTMATVRTFKEVLRDK+IGPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRDIYAALKKGSGTQEVATTMATVRTFKEVLRDKEIGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDA+LMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDAELMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQM RGF+LGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDGLWAAADQMTRGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARM GENPE+++FYITVYNEPYVQPPEPENFDPEG+LRG+Y Sbjct 690 VAYDPAFAYEIAYIVESGLARMFGENPEDVYFYITVYNEPYVQPPEPENFDPEGLLRGLY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYH ATEQR NKAQILASGVAMP+AL AA+MLA EWDVAADVWSVTSWGELNRDGVAI+ Sbjct 750 RYHVATEQRANKAQILASGVAMPSALNAAKMLADEWDVAADVWSVTSWGELNRDGVAIDR 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 +LRHPDRPAGVPYVT+AL +A GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 ARLRHPDRPAGVPYVTQALSDASGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRYFNTDAESQVVAVLEALA DGEIDPSVPVAAARQYRIDDV AAPEQT+DPG Sbjct 870 TRPAARRYFNTDAESQVVAVLEALARDGEIDPSVPVAAARQYRIDDVLAAPEQTSDPG 927 >gi|296166132|ref|ZP_06848577.1| pyruvate decarboxylase, E1 component of the pyruvate dehydrogenase complex [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898541|gb|EFG78102.1| pyruvate decarboxylase, E1 component of the pyruvate dehydrogenase complex [Mycobacterium parascrofulaceum ATCC BAA-614] Length=929 Score = 1730 bits (4480), Expect = 0.0, Method: Compositional matrix adjust. Identities = 827/898 (93%), Positives = 864/898 (97%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFD LL+R GP+RARYLMLRLLERAGEQRVAIP+LTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDDLLERSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERR+RAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRFRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQ+FIQGHASPGIYARAFLEGRL+ ++LDGFRQEHSH GGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQIFIQGHASPGIYARAFLEGRLSQDRLDGFRQEHSHAAGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDG YVRDHFFGRDPRTKALVENM+D +IWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVENMTDAEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGY+LG HF+GRNATHQMKKL LEDLK Sbjct 390 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLKH 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD+ RIP+SDAQL+ENPYLPPYYHPG +APEIRYMLDRRR LGGF+PERRTK+KAL LP Sbjct 450 FRDSMRIPISDAQLDENPYLPPYYHPGPDAPEIRYMLDRRRTLGGFLPERRTKAKALKLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 RDIYA LKKGSG+QEVATTMATVRTFKEVLRDK++GPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 ARDIYAALKKGSGNQEVATTMATVRTFKEVLRDKEVGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNR GQLYTAVDA+LMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 570 KIYNRLGQLYTAVDAELMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQM RGF+LGATAGRTTLTGEGLQHADGHSLLLA+TNPAV Sbjct 630 YIFYSMFGFQRTGDGLWAAADQMTRGFLLGATAGRTTLTGEGLQHADGHSLLLASTNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARM GENPEN++FY+TVYNEPYVQPPEPEN DPEGVLRGIY Sbjct 690 VAYDPAFAYEIAYIVESGLARMFGENPENVYFYMTVYNEPYVQPPEPENLDPEGVLRGIY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY AATEQR N AQILASGVAMP+AL+AA+MLAAEWDVAADVWSVTSWGELNRDG+++E Sbjct 750 RYRAATEQRANTAQILASGVAMPSALQAAEMLAAEWDVAADVWSVTSWGELNRDGISVER 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 KLRHPDRPAG YVT+AL A GPVIAVSDWMRAVPEQIRPWVPGT++TLGTDGFGFSD Sbjct 810 AKLRHPDRPAGTAYVTQALSGAGGPVIAVSDWMRAVPEQIRPWVPGTFVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRYFNTDAESQVVAVLEALA DGEIDPSVPVAAARQYRIDDV AAPEQT+DPG Sbjct 870 TRPAARRYFNTDAESQVVAVLEALARDGEIDPSVPVAAARQYRIDDVLAAPEQTSDPG 927 >gi|183983324|ref|YP_001851615.1| pyruvate dehydrogenase E1 component AceE [Mycobacterium marinum M] gi|183176650|gb|ACC41760.1| pyruvate dehydrogenase E1 component AceE [Mycobacterium marinum M] Length=929 Score = 1692 bits (4383), Expect = 0.0, Method: Compositional matrix adjust. Identities = 811/898 (91%), Positives = 848/898 (95%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFD LL+ GP+RARYLMLRLLERAGEQRVAIP+LTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYR WIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRL+A+QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHPGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAH+GALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLAHMGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMN+TPDGDYQTYKANDG YVRDHFFGRDPRTKALV NMSDQ+IWNL Sbjct 330 ALLHADRDGALVNLMNSTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGY+LG HF+GRNATHQMKKL L DLK Sbjct 390 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKR 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD+ RIPVSDAQL+E+PYLPPYYHPG +APEIRYMLDRRR LGGF+PER TK+K LTLP Sbjct 450 FRDSMRIPVSDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERPTKAKTLTLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 G D Y LKKGSG QEVATTMA VRTFKE+LRDK IG RIVPIIPDEARTFGMDSWFPSL Sbjct 510 GPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDA+LMLAYKES VGQILHEGINEAGSVGSF AAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDAELMLAYKESHVGQILHEGINEAGSVGSFTAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 V+YDPAFAYE+AYI+E+GL+RM GENPENI+FYITVYNEPYVQP EPENFDPEGVLRG+Y Sbjct 690 VSYDPAFAYELAYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY AAT+Q +KAQ+LASGV+MP AL+AAQMLA EWDVA DVWSVTSW ELNRDGV++E Sbjct 750 RYRAATKQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSELNRDGVSVER 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 +LRHP PAGV YVT ALE GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 HRLRHPGEPAGVAYVTTALEGTSGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRYFNTDAESQVVAVLEALA DGEID SV V AARQYRIDDV AAP+QT+D G Sbjct 870 TRPAARRYFNTDAESQVVAVLEALARDGEIDESVAVTAARQYRIDDVQAAPKQTSDSG 927 >gi|118617007|ref|YP_905339.1| pyruvate dehydrogenase subunit E1 [Mycobacterium ulcerans Agy99] gi|118569117|gb|ABL03868.1| pyruvate dehydrogenase E1 component AceE [Mycobacterium ulcerans Agy99] Length=929 Score = 1689 bits (4374), Expect = 0.0, Method: Compositional matrix adjust. Identities = 809/898 (91%), Positives = 848/898 (95%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFD LL+ GP+RARYLMLRLLERAGEQRVAIP+LTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDALLEHSGPARARYLMLRLLERAGEQRVAIPSLTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYR WIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRL+A+QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHPGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAH+GALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLAHMGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMN+TPDGDYQTYKANDG YVRDHFFGRDPRTKALV NMSDQ+IWNL Sbjct 330 ALLHADRDGALVNLMNSTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVANMSDQEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGY+LG HF+GRNATHQMKKL L DLK Sbjct 390 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALADLKR 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD+ RIPVSDAQL+E+PYLPPYYHPG +APEIRYMLDRRR LGGF+PER TK+K LTLP Sbjct 450 FRDSMRIPVSDAQLDEDPYLPPYYHPGSDAPEIRYMLDRRRTLGGFLPERPTKAKTLTLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 G D Y LKKGSG QEVATTMA VRTFKE+LRDK IG RIVPIIPDEARTFGMDSWFPSL Sbjct 510 GPDAYKVLKKGSGQQEVATTMALVRTFKELLRDKNIGNRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDA+LMLAYKES VGQILHEGINEAGSVGSF AAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDAELMLAYKESHVGQILHEGINEAGSVGSFTAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 V+YDPAFAYE+AYI+E+GL+RM GENPENI+FYITVYNEPYVQP EPENFDPEGVLRG+Y Sbjct 690 VSYDPAFAYELAYIIENGLSRMFGENPENIYFYITVYNEPYVQPAEPENFDPEGVLRGMY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY AAT+Q +KAQ+LASGV+MP AL+AAQMLA EWDVA DVWSVTSW ELNRDGV++E Sbjct 750 RYRAATKQCAHKAQLLASGVSMPDALKAAQMLADEWDVATDVWSVTSWSELNRDGVSVER 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 +LRHP PAGV YVT ALE GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFS+ Sbjct 810 HRLRHPGEPAGVAYVTTALEGTSGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSN 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRYFNTDAESQVVAVLEALA DGEID S+ V AARQYRIDDV AAP+QT+D G Sbjct 870 TRPAARRYFNTDAESQVVAVLEALARDGEIDESMAVTAARQYRIDDVQAAPKQTSDSG 927 >gi|289762405|ref|ZP_06521783.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis GM 1503] gi|289709911|gb|EFD73927.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis GM 1503] Length=811 Score = 1672 bits (4329), Expect = 0.0, Method: Compositional matrix adjust. Identities = 811/811 (100%), Positives = 811/811 (100%), Gaps = 0/811 (0%) Query 91 MVHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARA 150 MVHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARA Sbjct 1 MVHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKSHPGGGDQVFIQGHASPGIYARA 60 Query 151 FLEGRLTAEQLDGFRQEHSHVGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNH 210 FLEGRLTAEQLDGFRQEHSHVGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNH Sbjct 61 FLEGRLTAEQLDGFRQEHSHVGGGLPSYPHPRLMPDFWEFPTVSMGLGPLNAIYQARFNH 120 Query 211 YLHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVR 270 YLHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVR Sbjct 121 YLHDRGIKDTSDQHVWCFLGDGEMDEPESRGLAHVGALEGLDNLTFVINCNLQRLDGPVR 180 Query 271 GNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKAND 330 GNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKAND Sbjct 181 GNGKIIQELESFFRGAGWNVIKVVWGREWDALLHADRDGALVNLMNTTPDGDYQTYKAND 240 Query 331 GGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAK 390 GGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAK Sbjct 241 GGYVRDHFFGRDPRTKALVENMSDQDIWNLKRGGHDYRKVYAAYRAAVDHKGQPTVILAK 300 Query 391 TIKGYALGKHFEGRNATHQMKKLTLEDLKEFRDTQRIPVSDAQLEENPYLPPYYHPGLNA 450 TIKGYALGKHFEGRNATHQMKKLTLEDLKEFRDTQRIPVSDAQLEENPYLPPYYHPGLNA Sbjct 301 TIKGYALGKHFEGRNATHQMKKLTLEDLKEFRDTQRIPVSDAQLEENPYLPPYYHPGLNA 360 Query 451 PEIRYMLDRRRALGGFVPERRTKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEV 510 PEIRYMLDRRRALGGFVPERRTKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEV Sbjct 361 PEIRYMLDRRRALGGFVPERRTKSKALTLPGRDIYAPLKKGSGHQEVATTMATVRTFKEV 420 Query 511 LRDKQIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQIL 570 LRDKQIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQIL Sbjct 421 LRDKQIGPRIVPIIPDEARTFGMDSWFPSLKIYNRNGQLYTAVDADLMLAYKESEVGQIL 480 Query 571 HEGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAADQMARGFVLG 630 HEGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAADQMARGFVLG Sbjct 481 HEGINEAGSVGSFIAAGTSYATHNEPMIPIYIFYSMFGFQRTGDSFWAAADQMARGFVLG 540 Query 631 ATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEIAYIVESGLARMCGENPENI 690 ATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEIAYIVESGLARMCGENPENI Sbjct 541 ATAGRTTLTGEGLQHADGHSLLLAATNPAVVAYDPAFAYEIAYIVESGLARMCGENPENI 600 Query 691 FFYITVYNEPYVQPPEPENFDPEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQ 750 FFYITVYNEPYVQPPEPENFDPEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQ Sbjct 601 FFYITVYNEPYVQPPEPENFDPEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQ 660 Query 751 MLAAEWDVAADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVS 810 MLAAEWDVAADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVS Sbjct 661 MLAAEWDVAADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVS 720 Query 811 DWMRAVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEI 870 DWMRAVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEI Sbjct 721 DWMRAVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEI 780 Query 871 DPSVPVAAARQYRIDDVAAAPEQTTDPGPGA 901 DPSVPVAAARQYRIDDVAAAPEQTTDPGPGA Sbjct 781 DPSVPVAAARQYRIDDVAAAPEQTTDPGPGA 811 >gi|15827869|ref|NP_302132.1| pyruvate dehydrogenase subunit E1 [Mycobacterium leprae TN] gi|221230346|ref|YP_002503762.1| pyruvate dehydrogenase subunit E1 [Mycobacterium leprae Br4923] gi|13093421|emb|CAC30602.1| pyruvate dehydrogenase E1 component [Mycobacterium leprae] gi|219933453|emb|CAR71746.1| pyruvate dehydrogenase E1 component [Mycobacterium leprae Br4923] Length=936 Score = 1667 bits (4317), Expect = 0.0, Method: Compositional matrix adjust. Identities = 810/904 (90%), Positives = 852/904 (95%), Gaps = 4/904 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEET+EWLESFD LL+ GPSRARYL+LRLLERAGEQRV IPALT TDYVN Sbjct 30 VASYLPDIDPEETAEWLESFDELLKHSGPSRARYLILRLLERAGEQRVTIPALTWTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDED+ERRYR WIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDIERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHP GGDQVFIQGHASPGIYARAFLEGRL+A+QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPSGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHPGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFN YLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNRYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHV +LE LDNL FVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLAHVASLEDLDNLIFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALV+LMN TPDGDYQTYKANDG +VRDHFFGRDPRTKALVE+MSDQ+IWNL Sbjct 330 ALLHADRDGALVDLMNATPDGDYQTYKANDGRFVRDHFFGRDPRTKALVEHMSDQEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYA+YRAAVDHKGQPTVILAKTIKGYALGKHFE RNATHQMKKLTLEDLKE Sbjct 390 KRGGHDYRKVYASYRAAVDHKGQPTVILAKTIKGYALGKHFESRNATHQMKKLTLEDLKE 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRDTQRIP+SD +LEENPYLPPYYHPG ++PEIRY+LDRRRALGGF+PERRTKS ALTLP Sbjct 450 FRDTQRIPISDTELEENPYLPPYYHPGPDSPEIRYLLDRRRALGGFLPERRTKSGALTLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRD YA LK GSG QEVATTMA VRTFKEVLR K++GPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRDTYAALKTGSGQQEVATTMAIVRTFKEVLRHKEVGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYN NGQLYTAVDA LMLAYKESEVGQILHEGI+EAGSVGSFIAAGTSY+THNEPMIPI Sbjct 570 KIYNHNGQLYTAVDAQLMLAYKESEVGQILHEGIDEAGSVGSFIAAGTSYSTHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQMARGF+LGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDGLWAAADQMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 V YDPAFAYEIAYIVESGL RM GE+PEN+FFYITVYNEPY QPPEPENFDP+GVLRG+Y Sbjct 690 VTYDPAFAYEIAYIVESGLTRMFGEDPENVFFYITVYNEPYPQPPEPENFDPDGVLRGMY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY+ A EQR+NKA ILASGV+MPAAL AA+ML+ +WDVAADVWSVTSWGELNRDG++IET Sbjct 750 RYYTAKEQRSNKAHILASGVSMPAALTAAEMLSTQWDVAADVWSVTSWGELNRDGMSIET 809 Query 781 EKLRHPDRPAGVPYVTRALENAR----GPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGF 836 +LR+PD+P VPYVT+ L AR GPVIAVSDWMRAVPEQIRPWVPGTY+TLGTDGF Sbjct 810 ARLRYPDQPTSVPYVTQVLSEARSDNAGPVIAVSDWMRAVPEQIRPWVPGTYVTLGTDGF 869 Query 837 GFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTD 896 GFSDTR A RRYFNTDAESQVVAVLEALA DGEIDPSVPVAA RQY+IDDV AAPEQT+D Sbjct 870 GFSDTRTATRRYFNTDAESQVVAVLEALARDGEIDPSVPVAATRQYQIDDVQAAPEQTSD 929 Query 897 PGPG 900 PGPG Sbjct 930 PGPG 933 >gi|3150233|emb|CAA19205.1| pyruvate dehydrogenase e1 component [Mycobacterium leprae] Length=907 Score = 1665 bits (4311), Expect = 0.0, Method: Compositional matrix adjust. Identities = 809/904 (90%), Positives = 852/904 (95%), Gaps = 4/904 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +ASYLPDIDPEET+EWLESFD LL+ GPSRARYL+LRLLERAGEQRV IPALT TDYVN Sbjct 1 MASYLPDIDPEETAEWLESFDELLKHSGPSRARYLILRLLERAGEQRVTIPALTWTDYVN 60 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDED+ERRYR WIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 61 TIPTELEPWFPGDEDIERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHP GGDQVFIQGHASPGIYARAFLEGRL+A+QLDGFRQEHSH GGGLPSYPH Sbjct 121 NHFFRGKSHPSGGDQVFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHPGGGLPSYPH 180 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFN YLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNRYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHV +LE LDNL FVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 241 GLAHVASLEDLDNLIFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALV+LMN TPDGDYQTYKANDG +VRDHFFGRDPRTKALVE+MSDQ+IWNL Sbjct 301 ALLHADRDGALVDLMNATPDGDYQTYKANDGRFVRDHFFGRDPRTKALVEHMSDQEIWNL 360 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYA+YRAAVDHKGQPTVILAKTIKGYALGKHFE RNATHQMKKLTLEDLKE Sbjct 361 KRGGHDYRKVYASYRAAVDHKGQPTVILAKTIKGYALGKHFESRNATHQMKKLTLEDLKE 420 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRDTQRIP+SD +LEENPYLPPYYHPG ++PEIRY+LDRRRALGGF+PERRTKS ALTLP Sbjct 421 FRDTQRIPISDTELEENPYLPPYYHPGPDSPEIRYLLDRRRALGGFLPERRTKSGALTLP 480 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRD YA LK GSG QEVATTMA VRTFKEVLR K++GPRIVPIIPDEARTFGMDSWFPSL Sbjct 481 GRDTYAALKTGSGQQEVATTMAIVRTFKEVLRHKEVGPRIVPIIPDEARTFGMDSWFPSL 540 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYN NGQLYTAVDA LMLAYKESEVGQILHEGI+EAGSVGSFIAAGTSY+THNEPMIPI Sbjct 541 KIYNHNGQLYTAVDAQLMLAYKESEVGQILHEGIDEAGSVGSFIAAGTSYSTHNEPMIPI 600 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQMARGF+LGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 601 YIFYSMFGFQRTGDGLWAAADQMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 V YDPAFAYEIAYIVESGL RM GE+PEN+FFYITVYNEPY QPPEPENFDP+GVLRG+Y Sbjct 661 VTYDPAFAYEIAYIVESGLTRMFGEDPENVFFYITVYNEPYPQPPEPENFDPDGVLRGMY 720 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY+ A EQR+NKA ILASGV+MPAAL AA+ML+ +WDVAADVWSVTSWGELNRDG++IET Sbjct 721 RYYTAKEQRSNKAHILASGVSMPAALTAAEMLSTQWDVAADVWSVTSWGELNRDGMSIET 780 Query 781 EKLRHPDRPAGVPYVTRALENAR----GPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGF 836 +LR+PD+P VPYVT+ L AR GPVIAVSDWMRAVPEQIRPWVPGTY+TLGTDGF Sbjct 781 ARLRYPDQPTSVPYVTQVLSEARSDNAGPVIAVSDWMRAVPEQIRPWVPGTYVTLGTDGF 840 Query 837 GFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTD 896 GFSDTR A RRYFNTDAESQVVAVLEALA DGEIDPSVPVAA RQY+IDDV AAPEQT+D Sbjct 841 GFSDTRTATRRYFNTDAESQVVAVLEALARDGEIDPSVPVAATRQYQIDDVQAAPEQTSD 900 Query 897 PGPG 900 PGPG Sbjct 901 PGPG 904 >gi|315443827|ref|YP_004076706.1| pyruvate dehydrogenase E1 component, homodimeric type [Mycobacterium sp. Spyr1] gi|315262130|gb|ADT98871.1| pyruvate dehydrogenase E1 component, homodimeric type [Mycobacterium sp. Spyr1] Length=929 Score = 1659 bits (4296), Expect = 0.0, Method: Compositional matrix adjust. Identities = 793/898 (89%), Positives = 834/898 (93%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEET EWLESFD LL+R GP+RARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 30 VASYLPDIDPEETGEWLESFDDLLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLT +QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHAGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGP+NAIYQARFNHYLHDR IKDTS QHVW FLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRDIKDTSKQHVWAFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL V A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLIQVAANEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDG YVRDHFFGRDPRTKALVE M+D +IWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGSYVRDHFFGRDPRTKALVEPMTDAEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAY AA++HKGQPTVILAKTIKGY LGKHFEGRNATHQMKKL L+DLK+ Sbjct 390 KRGGHDYRKVYAAYHAAMEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKD 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD QRIPVSD+QLEENPYLPPYYHPG APEIRYMLDRRRALGGF+PERRTK+KALTLP Sbjct 450 FRDVQRIPVSDSQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERRTKTKALTLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRD Y LKKGSG QEVATTMATVRTFKE+LRDK IG RIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRDTYKALKKGSGKQEVATTMATVRTFKELLRDKNIGWRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDA+LMLAYKESEVGQILHEGINEAGS SF A GTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDAELMLAYKESEVGQILHEGINEAGSTASFTAVGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTL GEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLVGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 V+YDPAFA+EIAYI+ESGL RM G+NPEN++FY+T+YNEPYVQP EPE D EG+LRG+Y Sbjct 690 VSYDPAFAFEIAYIIESGLQRMYGDNPENVYFYMTIYNEPYVQPAEPEGIDVEGLLRGMY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY AA ++++N AQIL SGV+MP+AL+AA+MLA EWDVAADVWSVTSWGELNR+GVAIE Sbjct 750 RYQAAPQKKSNSAQILVSGVSMPSALKAAEMLAEEWDVAADVWSVTSWGELNREGVAIEK 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 E+LRHPDR PYVT AL A GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 ERLRHPDREVATPYVTEALAGAEGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRY+NTDAES VVAVLE LA DG ID S V AAR+Y IDDV AAPEQT+DPG Sbjct 870 TRPAARRYYNTDAESIVVAVLEGLARDGNIDISAAVDAARRYEIDDVMAAPEQTSDPG 927 >gi|120404711|ref|YP_954540.1| pyruvate dehydrogenase subunit E1 [Mycobacterium vanbaalenii PYR-1] gi|119957529|gb|ABM14534.1| 2-oxo-acid dehydrogenase E1 subunit, homodimeric type [Mycobacterium vanbaalenii PYR-1] Length=924 Score = 1658 bits (4294), Expect = 0.0, Method: Compositional matrix adjust. Identities = 790/898 (88%), Positives = 836/898 (94%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEET EWLESFD LL+R GP+RARYLMLRLLER+ E+RVAIPALTSTDYVN Sbjct 25 VASYLPDIDPEETGEWLESFDDLLERSGPARARYLMLRLLERSREKRVAIPALTSTDYVN 84 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 85 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 144 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQ+FIQGHASPGIYARA+LEGRL+A+QLDGFRQEHSH GGGLPSYPH Sbjct 145 NHFFRGKSHPGGGDQIFIQGHASPGIYARAYLEGRLSADQLDGFRQEHSHPGGGLPSYPH 204 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDTS QHVW FLGDGEMDEPESR Sbjct 205 PRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSKQHVWAFLGDGEMDEPESR 264 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL V A E LDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 265 GLIQVAANEALDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 324 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDG YVRDHFFGRDPRTKALVENM+D++IWNL Sbjct 325 ALLHADRDGALVNLMNTTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVENMTDREIWNL 384 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAY AA++HKGQPTVILAKTIKGY LGKHFEGRNATHQMKKL L+DLK+ Sbjct 385 KRGGHDYRKVYAAYHAALEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKD 444 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD QRIPVSD QLE +PYLPPYYHPG APEIRYMLDRRRALGGF+PERRTKS+ALTLP Sbjct 445 FRDAQRIPVSDEQLEADPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERRTKSRALTLP 504 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRD+Y LKKGSG QEVATTMATVRTFKE+LRDK IG RIVPIIPDEARTFGMDSWFPSL Sbjct 505 GRDVYKALKKGSGKQEVATTMATVRTFKELLRDKNIGSRIVPIIPDEARTFGMDSWFPSL 564 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDA+LMLAYKESE+GQILHEGINEAGS SF A GTSYATHNEPMIPI Sbjct 565 KIYNRNGQLYTAVDAELMLAYKESEIGQILHEGINEAGSTASFTAVGTSYATHNEPMIPI 624 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTL GEGLQHADGHSLLLA+TNPAV Sbjct 625 YIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLVGEGLQHADGHSLLLASTNPAV 684 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYI+ESGL RM GENPEN++FY+T+YNEPYVQP EP+ D EG+LRG+Y Sbjct 685 VAYDPAFAYEIAYIIESGLHRMYGENPENVYFYMTIYNEPYVQPAEPDGLDVEGLLRGMY 744 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY AA E+RTN AQIL SGV MP+AL+AA++LA EWDVAADVWSVTSWGELNRDGVAIE Sbjct 745 RYQAAPEKRTNAAQILVSGVGMPSALKAAELLAQEWDVAADVWSVTSWGELNRDGVAIER 804 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 EKLRHP+ PA PYVT+ L A GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 805 EKLRHPELPAATPYVTKMLAEAAGPVVAVSDWMRAVPEQIRPWVPGTYITLGTDGFGFSD 864 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRY+NTDAES VVAVLE LA DG ID SV V AA++Y IDDV AAPEQT+DPG Sbjct 865 TRPAARRYYNTDAESVVVAVLEGLARDGNIDISVAVEAAKKYEIDDVMAAPEQTSDPG 922 >gi|145223368|ref|YP_001134046.1| pyruvate dehydrogenase subunit E1 [Mycobacterium gilvum PYR-GCK] gi|145215854|gb|ABP45258.1| 2-oxo-acid dehydrogenase E1 subunit, homodimeric type [Mycobacterium gilvum PYR-GCK] Length=929 Score = 1658 bits (4293), Expect = 0.0, Method: Compositional matrix adjust. Identities = 792/898 (89%), Positives = 834/898 (93%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEET EWLESFD LL+R GP+RARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 30 VASYLPDIDPEETGEWLESFDDLLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLT +QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHAGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGP+NAIYQARFNHYLHDR IKDTS QHVW FLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRDIKDTSKQHVWAFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL V A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLIQVAANEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDG YVRDHFFGRDPRTKALVE M+D +IWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGSYVRDHFFGRDPRTKALVEPMTDAEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAY AA++HKGQPTVILAKTIKGY LGKHFEGRNATHQMKKL L+DLK+ Sbjct 390 KRGGHDYRKVYAAYHAAMEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKD 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD QRIPVSD+QLEENPYLPPYYHPG APEIRYMLDRRRALGGF+PERRTK+KALTLP Sbjct 450 FRDVQRIPVSDSQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFLPERRTKTKALTLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRD Y LKKGSG QEVATTMATVRTFKE+LRDK IG RIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRDTYKALKKGSGKQEVATTMATVRTFKELLRDKNIGWRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDA+LMLAYKESEVGQILHEGINEAGS SF A GTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDAELMLAYKESEVGQILHEGINEAGSTASFTAVGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTL GEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLVGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 V+YDPAFA+EIAYI+ESGL RM G+NPEN++FY+T+YNEPYVQP EPE D EG+LRG+Y Sbjct 690 VSYDPAFAFEIAYIIESGLQRMYGDNPENVYFYMTIYNEPYVQPAEPEGIDVEGLLRGMY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY AA ++++N AQIL SGV+MP+AL+AA+MLA EWDV+ADVWSVTSWGELNR+GVAIE Sbjct 750 RYQAAPQKKSNSAQILVSGVSMPSALKAAEMLAEEWDVSADVWSVTSWGELNREGVAIEK 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 E+LRHPDR PYVT AL A GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 ERLRHPDREVATPYVTEALAGAEGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRY+NTDAES VVAVLE LA DG ID S V AAR+Y IDDV AAPEQT+DPG Sbjct 870 TRPAARRYYNTDAESIVVAVLEGLARDGNIDISAAVDAARRYEIDDVMAAPEQTSDPG 927 >gi|240170076|ref|ZP_04748735.1| pyruvate dehydrogenase subunit E1 [Mycobacterium kansasii ATCC 12478] Length=930 Score = 1656 bits (4288), Expect = 0.0, Method: Compositional matrix adjust. Identities = 799/887 (91%), Positives = 847/887 (96%), Gaps = 0/887 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFD +L+R GPSRARYLMLRLLERAGEQRVAIP+LTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDEMLERSGPSRARYLMLRLLERAGEQRVAIPSLTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYR WIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRTWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQ+FIQGHASPGIYARAFLEGRL+A+QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQIFIQGHASPGIYARAFLEGRLSADQLDGFRQEHSHPGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTS+QHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSEQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAH+GALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLAHIGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDG YVRDHFFGRDPRTKALV++M+D +IWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVQDMTDSEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAV+H+GQPTVILAKTIKGY+LG HF+GRNATHQMKKL LEDLK Sbjct 390 KRGGHDYRKVYAAYRAAVEHQGQPTVILAKTIKGYSLGAHFQGRNATHQMKKLALEDLKY 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD RIP+ DAQLEE+PYLPPYYHPG +APEIRYMLDRRR LGGFVPERRTK+KAL LP Sbjct 450 FRDAMRIPIDDAQLEEDPYLPPYYHPGPDAPEIRYMLDRRRTLGGFVPERRTKAKALKLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GR+IYA LKKGSG+QEVATTMA VRTFKEVLRDK++GPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRNIYAALKKGSGNQEVATTMAMVRTFKEVLRDKEVGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNR GQLYTAVDA+LMLAY+ES G ILHEGINEAG+VGSFIAAGTSYATHNEPMIP+ Sbjct 570 KIYNRLGQLYTAVDAELMLAYRESHDGHILHEGINEAGAVGSFIAAGTSYATHNEPMIPV 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAA DQMARGF+LGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDGLWAAGDQMARGFLLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 V+YDPAFAYEIAYIVESGLARM GENPEN+FFYITVYNEPYVQPPEPENFDPEGVLRGIY Sbjct 690 VSYDPAFAYEIAYIVESGLARMFGENPENVFFYITVYNEPYVQPPEPENFDPEGVLRGIY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY AATEQR++KAQILASGV+MP ALRAA++LAAEWDVAADVWSVTSW ELNRDGV++E Sbjct 750 RYRAATEQRSSKAQILASGVSMPDALRAAELLAAEWDVAADVWSVTSWSELNRDGVSVEK 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 ++LR+P +PAG YVT+ L GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 QRLRNPGQPAGEAYVTKVLAGTAGPVVAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDV 887 TRPAARRYFNTDAES VVAVL+ALA DGEIDPSV VAAARQY+ID+V Sbjct 870 TRPAARRYFNTDAESTVVAVLDALARDGEIDPSVAVAAARQYQIDNV 916 >gi|119869456|ref|YP_939408.1| pyruvate dehydrogenase subunit E1 [Mycobacterium sp. KMS] gi|119695545|gb|ABL92618.1| 2-oxo-acid dehydrogenase E1 subunit, homodimeric type [Mycobacterium sp. KMS] Length=929 Score = 1650 bits (4272), Expect = 0.0, Method: Compositional matrix adjust. Identities = 798/898 (89%), Positives = 845/898 (95%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ETSEWLESFD LL+R GP+RARYL+LRLLER+GEQRVAIPALTSTDYVN Sbjct 30 VASYLPDIDPDETSEWLESFDQLLERSGPARARYLLLRLLERSGEQRVAIPALTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSH GGGDQVFIQGHASPGIYARA+LEGRLTA+QLDGFRQEHSH GGG+PSYPH Sbjct 150 NHFFRGKSHSGGGDQVFIQGHASPGIYARAYLEGRLTADQLDGFRQEHSHPGGGIPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDT+DQHVW FLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTTDQHVWAFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL HV ALE LDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLIHVAALEALDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVE M+D +IWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVEPMTDAEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAA++HKGQPTVILAKTIKGY LGKHFEGRNATHQMKKL L+DLK+ Sbjct 390 KRGGHDYRKVYAAYRAAMEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKD 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD QRIP+ DAQLEENPYLPPYYHPG APEIRYMLDRRRALGGFVPERRTKSKAL LP Sbjct 450 FRDAQRIPIGDAQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFVPERRTKSKALALP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 D Y LKKGSG QEVATTMATVRTFKE+LRDKQIG RIVPIIPDEARTFGMDSWFP+L Sbjct 510 SSDAYKALKKGSGKQEVATTMATVRTFKEILRDKQIGHRIVPIIPDEARTFGMDSWFPNL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYT+VDA+LMLAY+ESEVGQILHEGINEAGSVG+FIAAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTSVDAELMLAYRESEVGQILHEGINEAGSVGTFIAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTL GEGLQHADGHSLLLA+TNPAV Sbjct 630 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLVGEGLQHADGHSLLLASTNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYI+ESGL RM GENPEN++FY+T+YNEPYVQP EPEN D EG+LRGIY Sbjct 690 VAYDPAFAYEIAYIIESGLHRMYGENPENVYFYLTIYNEPYVQPAEPENLDVEGLLRGIY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY AA E+++N AQIL SGVAMP+AL+AA+MLA EWDVAADVWSVTSW ELNRDGV +E Sbjct 750 RYRAAAEKKSNTAQILVSGVAMPSALKAAEMLAEEWDVAADVWSVTSWNELNRDGVQVEK 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 + LRHPDRPAG PY+T AL +A GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 DLLRHPDRPAGTPYITTALADAAGPVVAVSDWMRAVPEQIRPWVPGTYITLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARR++NTDAES VAVLE LA DG ID SV V AAR+Y IDDV AAPEQT+DPG Sbjct 870 TRPAARRFYNTDAESITVAVLEGLARDGNIDISVAVEAARRYEIDDVLAAPEQTSDPG 927 >gi|108800328|ref|YP_640525.1| pyruvate dehydrogenase subunit E1 [Mycobacterium sp. MCS] gi|126435951|ref|YP_001071642.1| pyruvate dehydrogenase subunit E1 [Mycobacterium sp. JLS] gi|108770747|gb|ABG09469.1| 2-oxo-acid dehydrogenase E1 component, homodimeric type [Mycobacterium sp. MCS] gi|126235751|gb|ABN99151.1| 2-oxo-acid dehydrogenase E1 subunit, homodimeric type [Mycobacterium sp. JLS] Length=924 Score = 1648 bits (4267), Expect = 0.0, Method: Compositional matrix adjust. Identities = 798/898 (89%), Positives = 845/898 (95%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ETSEWLESFD LL+R GP+RARYL+LRLLER+GEQRVAIPALTSTDYVN Sbjct 25 VASYLPDIDPDETSEWLESFDQLLERSGPARARYLLLRLLERSGEQRVAIPALTSTDYVN 84 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 85 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 144 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSH GGGDQVFIQGHASPGIYARA+LEGRLTA+QLDGFRQEHSH GGG+PSYPH Sbjct 145 NHFFRGKSHSGGGDQVFIQGHASPGIYARAYLEGRLTADQLDGFRQEHSHPGGGIPSYPH 204 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDT+DQHVW FLGDGEMDEPESR Sbjct 205 PRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTTDQHVWAFLGDGEMDEPESR 264 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL HV ALE LDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 265 GLIHVAALEALDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 324 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVE M+D +IWNL Sbjct 325 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVEPMTDAEIWNL 384 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAA++HKGQPTVILAKTIKGY LGKHFEGRNATHQMKKL L+DLK+ Sbjct 385 KRGGHDYRKVYAAYRAAMEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLALQDLKD 444 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD QRIP+ DAQLEENPYLPPYYHPG APEIRYMLDRRRALGGFVPERRTKSKAL LP Sbjct 445 FRDAQRIPIGDAQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFVPERRTKSKALALP 504 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 D Y LKKGSG QEVATTMATVRTFKE+LRDKQIG RIVPIIPDEARTFGMDSWFP+L Sbjct 505 SSDAYKALKKGSGKQEVATTMATVRTFKEILRDKQIGHRIVPIIPDEARTFGMDSWFPNL 564 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYT+VDA+LMLAY+ESEVGQILHEGINEAGSVG+FIAAGTSYATHNEPMIPI Sbjct 565 KIYNRNGQLYTSVDAELMLAYRESEVGQILHEGINEAGSVGTFIAAGTSYATHNEPMIPI 624 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTL GEGLQHADGHSLLLA+TNPAV Sbjct 625 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLVGEGLQHADGHSLLLASTNPAV 684 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYI+ESGL RM GENPEN++FY+T+YNEPYVQP EPEN D EG+LRGIY Sbjct 685 VAYDPAFAYEIAYIIESGLHRMYGENPENVYFYLTIYNEPYVQPAEPENLDVEGLLRGIY 744 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RY AA E+++N AQIL SGVAMP+AL+AA+MLA EWDVAADVWSVTSW ELNRDGV +E Sbjct 745 RYRAAAEKKSNTAQILVSGVAMPSALKAAEMLAEEWDVAADVWSVTSWNELNRDGVQVEK 804 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 + LRHPDRPAG PY+T AL +A GPV+AVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 805 DLLRHPDRPAGTPYITTALADAAGPVVAVSDWMRAVPEQIRPWVPGTYITLGTDGFGFSD 864 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARR++NTDAES VAVLE LA DG ID SV V AAR+Y IDDV AAPEQT+DPG Sbjct 865 TRPAARRFYNTDAESITVAVLEGLARDGNIDISVAVEAARRYEIDDVLAAPEQTSDPG 922 >gi|118470577|ref|YP_888598.1| pyruvate dehydrogenase subunit E1 [Mycobacterium smegmatis str. MC2 155] gi|302425123|sp|A0R0B0.1|ODP1_MYCS2 RecName: Full=Pyruvate dehydrogenase E1 component gi|118171864|gb|ABK72760.1| pyruvate dehydrogenase E1 component [Mycobacterium smegmatis str. MC2 155] Length=929 Score = 1626 bits (4211), Expect = 0.0, Method: Compositional matrix adjust. Identities = 778/898 (87%), Positives = 820/898 (92%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDID EET+EWLESFD LL+R GP+RARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 30 VASYLPDIDTEETAEWLESFDELLERSGPARARYLMLRLLERAGEQRVAIPALTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSA LYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGD VFIQGHASPGIYARAFLEGRLT +QLDGFRQEHSH GGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDHVFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHSGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDTSDQHVW FLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSDQHVWAFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL V A E LDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLIQVAANEALDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 LLHADRDGALVNLMN+TPDGDYQTYKANDG YVRDHFFGRDPRTKALV +MSDQ+IWNL Sbjct 330 VLLHADRDGALVNLMNSTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVADMSDQEIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAA++HKGQPTVILAKTIKGY LG+HFEGRNATHQMKKL LEDLK Sbjct 390 KRGGHDYRKVYAAYRAAMEHKGQPTVILAKTIKGYTLGQHFEGRNATHQMKKLALEDLKN 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD R+PVSDAQLEE+PYLPPYYHPG APEIRY+L+RRRALGGFVP RRTKSK L LP Sbjct 450 FRDVTRVPVSDAQLEEDPYLPPYYHPGPEAPEIRYLLERRRALGGFVPSRRTKSKPLALP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 G D Y LKKGSG Q VATTMATVRTFKE+LRDK IGPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 GSDTYKALKKGSGSQAVATTMATVRTFKELLRDKNIGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYT+VD++LMLAYKESEVGQILHEGINEAGS SF A GTSY+TH+EPMIPI Sbjct 570 KIYNRNGQLYTSVDSELMLAYKESEVGQILHEGINEAGSTSSFTAVGTSYSTHDEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA+TNPA Sbjct 630 YIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAA 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 V YDPAFAYEIA+I+ESGL RM GE+PEN+FFY+T+YNEPY QP EPEN D E +L+G+Y Sbjct 690 VTYDPAFAYEIAHIIESGLQRMYGEDPENVFFYLTIYNEPYQQPAEPENLDVEALLKGLY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 Y A E+R AQILASGVAMP ALRAA +LA++WDVAADVWSVTSWGELNR+GVAIE Sbjct 750 LYRPAPEKRAKSAQILASGVAMPEALRAADLLASDWDVAADVWSVTSWGELNREGVAIEK 809 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 +LRHPD PAG P+VT AL +A GPVIAVSDWMRAVPEQIRPWVPGTY+TLGTDGFGFSD Sbjct 810 HRLRHPDEPAGTPHVTSALADAAGPVIAVSDWMRAVPEQIRPWVPGTYVTLGTDGFGFSD 869 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARRYFNTDAES VVAVL+ LA DGEID SV AA QYRIDDV+AA D G Sbjct 870 TRPAARRYFNTDAESVVVAVLQGLARDGEIDASVAAQAAEQYRIDDVSAAGVSYADTG 927 >gi|289750838|ref|ZP_06510216.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis T92] gi|289691425|gb|EFD58854.1| pyruvate dehydrogenase subunit E1 [Mycobacterium tuberculosis T92] Length=813 Score = 1625 bits (4209), Expect = 0.0, Method: Compositional matrix adjust. Identities = 784/784 (100%), Positives = 784/784 (100%), Gaps = 0/784 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 30 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 89 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 90 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 149 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH Sbjct 150 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 209 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 210 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 269 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 270 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 329 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL Sbjct 330 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 389 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE Sbjct 390 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 449 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP Sbjct 450 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 509 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL Sbjct 510 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 569 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI Sbjct 570 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 629 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 630 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 689 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY Sbjct 690 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 749 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET Sbjct 750 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 809 Query 781 EKLR 784 EKLR Sbjct 810 EKLR 813 >gi|333990294|ref|YP_004522908.1| pyruvate dehydrogenase E1 component AceE [Mycobacterium sp. JDM601] gi|333486262|gb|AEF35654.1| pyruvate dehydrogenase E1 component AceE [Mycobacterium sp. JDM601] Length=908 Score = 1603 bits (4152), Expect = 0.0, Method: Compositional matrix adjust. Identities = 777/901 (87%), Positives = 841/901 (94%), Gaps = 3/901 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEETSEWLESFD L+ R GP+RARYLMLRLLERAGEQRVAIPALTSTDYVN Sbjct 6 VASYLPDIDPEETSEWLESFDGLVARSGPARARYLMLRLLERAGEQRVAIPALTSTDYVN 65 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDED+ERRYRAWIRWNAA+MVHRAQRPGVGVGGHISTYASSA+LYEVGF Sbjct 66 TIPTELEPWFPGDEDIERRYRAWIRWNAAVMVHRAQRPGVGVGGHISTYASSASLYEVGF 125 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRGK HPGGGDQ+FIQGHASPGIYARAFLEGRL+ QLDGFRQEHSH GGLPSYPH Sbjct 126 NHFFRGKDHPGGGDQIFIQGHASPGIYARAFLEGRLSTHQLDGFRQEHSHPDGGLPSYPH 185 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR Sbjct 186 PRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 245 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GL HVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 246 GLLHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 305 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMN TPDGDYQTYKANDGGYVR HFFGRDPRTKALVEN+SDQDIW+L Sbjct 306 ALLHADRDGALVNLMNVTPDGDYQTYKANDGGYVRQHFFGRDPRTKALVENLSDQDIWHL 365 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAAV+H+GQPTVILAKTIKGY+LG +F GRNATHQMKK +DLK+ Sbjct 366 KRGGHDYRKVYAAYRAAVEHQGQPTVILAKTIKGYSLGSYFAGRNATHQMKKFRPQDLKD 425 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD RIP+SDA++EENPYLPPYYHPG +APEIRY+LDRRRALGGFVP+RRT+++ALTLP Sbjct 426 FRDEMRIPISDAEIEENPYLPPYYHPGEDAPEIRYLLDRRRALGGFVPQRRTRARALTLP 485 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 G + YA +KKGSG QEVATTMATVR FKE+LRDK+IG R+VPIIPDEARTFGMDSWFPSL Sbjct 486 GPEAYAAVKKGSGTQEVATTMATVRVFKELLRDKEIGTRLVPIIPDEARTFGMDSWFPSL 545 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYT+VDA+LMLAYKESEVGQILHEGINEAGS SF A GTSYATH+EPMIPI Sbjct 546 KIYNRNGQLYTSVDAELMLAYKESEVGQILHEGINEAGSTASFTAVGTSYATHDEPMIPI 605 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGDS WAAADQMARGF+LGATAGRTTLTGEGLQHADGHSLLLAATNPAV Sbjct 606 YIFYSMFGFQRTGDSLWAAADQMARGFILGATAGRTTLTGEGLQHADGHSLLLAATNPAV 665 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPE---GVLR 717 V+YDPAFA+E+A+I+ESGL RM GENPEN++FY+T+YNEPY+QP EP+ FD E G+LR Sbjct 666 VSYDPAFAFEVAHIIESGLQRMFGENPENVYFYVTLYNEPYIQPAEPDGFDAEDVAGLLR 725 Query 718 GIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVA 777 GIYRY A E +++ AQILASGV+MP ALRAA++LAA+WDVAADVWSVTSWGELNRDGVA Sbjct 726 GIYRYQKAAEPKSHAAQILASGVSMPEALRAAELLAADWDVAADVWSVTSWGELNRDGVA 785 Query 778 IETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFG 837 +E E+LRHP+RPAG PYVTRAL +A GPV+AVSDWMRAVPEQIRPWVPGT++TLGTDGFG Sbjct 786 LERERLRHPERPAGEPYVTRALADAAGPVVAVSDWMRAVPEQIRPWVPGTFVTLGTDGFG 845 Query 838 FSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDP 897 FSDTR AARRYFNTDAES VAVL ALA DG ID S+P AA +Y+IDDV AAPEQT+D Sbjct 846 FSDTRTAARRYFNTDAESVAVAVLAALARDGAIDASIPATAADRYQIDDVMAAPEQTSDS 905 Query 898 G 898 G Sbjct 906 G 906 >gi|169628972|ref|YP_001702621.1| pyruvate dehydrogenase subunit E1 [Mycobacterium abscessus ATCC 19977] gi|169240939|emb|CAM61967.1| Probable pyruvate dehydrogenase E1 component AceE [Mycobacterium abscessus] Length=905 Score = 1587 bits (4109), Expect = 0.0, Method: Compositional matrix adjust. Identities = 758/898 (85%), Positives = 813/898 (91%), Gaps = 0/898 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ET EWLESFD LL R GP+RARYLMLRLLERA RVAIPALTSTDYVN Sbjct 6 VASYLPDIDPDETGEWLESFDGLLARSGPARARYLMLRLLERANAGRVAIPALTSTDYVN 65 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDED ERR+RAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 66 TIPTENEPWFPGDEDTERRFRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 125 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVGGGLPSYPH 180 NHFFRG +HPGGGDQ+FIQGHASPGIYARAFLEGRLT +QLDGFRQE SH GGGLPSYPH Sbjct 126 NHFFRGNAHPGGGDQIFIQGHASPGIYARAFLEGRLTTDQLDGFRQEKSHPGGGLPSYPH 185 Query 181 PRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPESR 240 PRLMPDFW+FPTVSMGLGP+NAI QARFNHYL DRGIKDTSDQ VW FLGDGEMDEPESR Sbjct 186 PRLMPDFWQFPTVSMGLGPMNAIMQARFNHYLRDRGIKDTSDQRVWAFLGDGEMDEPESR 245 Query 241 GLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 300 GLAH+ A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD Sbjct 246 GLAHIAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGREWD 305 Query 301 ALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIWNL 360 ALLHADRDGALVNLMNTT DGDYQTYKANDG YVR+HFFGRDPRTK LV++++D +WNL Sbjct 306 ALLHADRDGALVNLMNTTADGDYQTYKANDGAYVREHFFGRDPRTKELVKDLTDAQVWNL 365 Query 361 KRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDLKE 420 KRGGHDYRKVYAAYRAA +HKGQPTVILAKTIKGY LGKHFEGRNATHQMKKLTL+DLK+ Sbjct 366 KRGGHDYRKVYAAYRAATEHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLTLDDLKD 425 Query 421 FRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALTLP 480 FRD QRIP+SDAQLEENPYLPPYYHPG APEIRYMLDRRRALGGFVP RRT S+ LTLP Sbjct 426 FRDKQRIPISDAQLEENPYLPPYYHPGPEAPEIRYMLDRRRALGGFVPSRRTTSRPLTLP 485 Query 481 GRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFPSL 540 G + YA +KKGSG QEVATTMA VRTFKE+LRDK IG RIVPIIPDEARTFGMDSWFPSL Sbjct 486 GSETYASIKKGSGKQEVATTMALVRTFKELLRDKNIGNRIVPIIPDEARTFGMDSWFPSL 545 Query 541 KIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMIPI 600 KIYNRNGQLYT+VDA+LMLAYKES GQILHEGINEAGS SF A GT+Y+TH+EPMIP+ Sbjct 546 KIYNRNGQLYTSVDAELMLAYKESAQGQILHEGINEAGSTASFTAVGTAYSTHDEPMIPL 605 Query 601 YIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNPAV 660 YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA+TNPAV Sbjct 606 YIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNPAV 665 Query 661 VAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRGIY 720 VAYDPAFAYEIA+IVE GL RM GEN EN++FYIT+YNEPYVQP EPEN D EG+LRGIY Sbjct 666 VAYDPAFAYEIAHIVEHGLQRMYGENSENVYFYITLYNEPYVQPAEPENVDTEGILRGIY 725 Query 721 RYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAIET 780 ++ AA E RT++A ILASGV++P ALRAA +LA +WDVAADVWSVTSWGELNRDG+AI+ Sbjct 726 KFRAAPEARTHRANILASGVSVPDALRAADLLAEQWDVAADVWSVTSWGELNRDGLAIDH 785 Query 781 EKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGFSD 840 + LRHPDRP GVPYVT+ALE A+GP +AVSDWM AVPEQIRPWVPG Y TLG DGFG SD Sbjct 786 QALRHPDRPKGVPYVTKALEGAQGPKVAVSDWMHAVPEQIRPWVPGMYRTLGADGFGISD 845 Query 841 TRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 TRPAARR+FNTDAES VVAVLEALA +G +D V V AA QY+IDDV+AA D G Sbjct 846 TRPAARRFFNTDAESVVVAVLEALADEGSVDRQVAVTAAAQYKIDDVSAADVSYKDTG 903 >gi|325676998|ref|ZP_08156669.1| pyruvate decarboxylase, E1 component of the pyruvate dehydrogenase complex [Rhodococcus equi ATCC 33707] gi|325552160|gb|EGD21851.1| pyruvate decarboxylase, E1 component of the pyruvate dehydrogenase complex [Rhodococcus equi ATCC 33707] Length=980 Score = 1498 bits (3878), Expect = 0.0, Method: Compositional matrix adjust. Identities = 730/907 (81%), Positives = 791/907 (88%), Gaps = 10/907 (1%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ET+EWLESFD LL R G +RARYLMLRLLERAGE+ VAIPALTSTDYVN Sbjct 73 VASYLPDIDPDETTEWLESFDGLLDRSGSARARYLMLRLLERAGEKHVAIPALTSTDYVN 132 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 133 TIPTENEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 192 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV--GGGLPSY 178 NHFFRGK HPGGGD +F+QGHASPGIYARAFLEGR+ AEQ+DGFRQE SH GGGLPSY Sbjct 193 NHFFRGKDHPGGGDHIFVQGHASPGIYARAFLEGRIPAEQMDGFRQEASHAQSGGGLPSY 252 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+PDFWEFPTVSMGLGP+NAIYQARFNHYL+DRG+KDTSDQHVW FLGDGEMDEPE Sbjct 253 PHPRLLPDFWEFPTVSMGLGPMNAIYQARFNHYLNDRGVKDTSDQHVWAFLGDGEMDEPE 312 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGLAHV A EGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE Sbjct 313 SRGLAHVAATEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 372 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHAD+DGALVNLMN TPDGD+QTYKANDG +VR+HFFGRDPRTKALV +MSDQ+IW Sbjct 373 WDALLHADKDGALVNLMNETPDGDFQTYKANDGAFVREHFFGRDPRTKALVADMSDQEIW 432 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRK++AAY AA+ HKGQPTVILA TIKGY LGKHFEGRNATHQMKKLTL+DL Sbjct 433 NLKRGGHDYRKIHAAYAAAMAHKGQPTVILAHTIKGYTLGKHFEGRNATHQMKKLTLDDL 492 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD QRIP+SDA+LE++PYLPPYYHPG ++PEI+YML RR+ALGGF+P RRT + L Sbjct 493 KRFRDIQRIPISDAELEKDPYLPPYYHPGPDSPEIQYMLQRRKALGGFLPSRRTDAAPLP 552 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 P Y ++KGSG QEVATTMA VR KE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 553 QPADKTYDVVRKGSGKQEVATTMAVVRILKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 612 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNRNGQLYT+VDA+LMLAYKES VGQILHEGINEAGS SF A GTSYATH EPMI Sbjct 613 SLKIYNRNGQLYTSVDAELMLAYKESTVGQILHEGINEAGSTSSFTAVGTSYATHGEPMI 672 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA+TNP Sbjct 673 PVYIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNP 732 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENP-------ENIFFYITVYNEPYVQPPEPENFD 711 A V+YDP+F+YEIA+IV+ GL RM G P ENIF+Y+TVYNEPY QP EPEN D Sbjct 733 AAVSYDPSFSYEIAHIVKDGLRRMYGGTPGVDGFGGENIFYYLTVYNEPYQQPAEPENLD 792 Query 712 PEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL 771 EG+L+GIY Y A E +AQIL SGV MP LRA ++LA EW VAADVWSVTSWGEL Sbjct 793 VEGLLKGIYLYKPA-EGSGPRAQILVSGVTMPDGLRAQRLLADEWGVAADVWSVTSWGEL 851 Query 772 NRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTL 831 RDGV E E L +P A PYVT+AL A+GP +A SDWMRAVP+QIR WVPG+Y TL Sbjct 852 RRDGVECEREALHNPGADAPTPYVTKALSQAQGPFVAASDWMRAVPDQIRQWVPGSYTTL 911 Query 832 GTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAP 891 GTDGFGFSDTRPAARR+FN DAES VVAVL ALA GE+D S V AA +YRIDDV AAP Sbjct 912 GTDGFGFSDTRPAARRFFNVDAESIVVAVLSALAKSGEVDRSKAVEAAARYRIDDVLAAP 971 Query 892 EQTTDPG 898 DPG Sbjct 972 VSMADPG 978 >gi|312140255|ref|YP_004007591.1| pyruvate dehydrogenase acee [Rhodococcus equi 103S] gi|311889594|emb|CBH48911.1| pyruvate dehydrogenase AceE [Rhodococcus equi 103S] Length=968 Score = 1497 bits (3876), Expect = 0.0, Method: Compositional matrix adjust. Identities = 730/907 (81%), Positives = 791/907 (88%), Gaps = 10/907 (1%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ET+EWLESFD LL R G +RARYLMLRLLERAGE+ VAIPALTSTDYVN Sbjct 61 VASYLPDIDPDETTEWLESFDGLLDRSGSARARYLMLRLLERAGEKHVAIPALTSTDYVN 120 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 121 TIPTENEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 180 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV--GGGLPSY 178 NHFFRGK HPGGGD +F+QGHASPGIYARAFLEGR+ AEQ+DGFRQE SH GGGLPSY Sbjct 181 NHFFRGKDHPGGGDHIFVQGHASPGIYARAFLEGRIPAEQMDGFRQEASHAQSGGGLPSY 240 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+PDFWEFPTVSMGLGP+NAIYQARFNHYL+DRG+KDTSDQHVW FLGDGEMDEPE Sbjct 241 PHPRLLPDFWEFPTVSMGLGPMNAIYQARFNHYLNDRGVKDTSDQHVWAFLGDGEMDEPE 300 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGLAHV A EGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE Sbjct 301 SRGLAHVAATEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 360 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHAD+DGALVNLMN TPDGD+QTYKANDG +VR+HFFGRDPRTKALV +MSDQ+IW Sbjct 361 WDALLHADKDGALVNLMNETPDGDFQTYKANDGAFVREHFFGRDPRTKALVADMSDQEIW 420 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRK++AAY AA+ HKGQPTVILA TIKGY LGKHFEGRNATHQMKKLTL+DL Sbjct 421 NLKRGGHDYRKIHAAYAAAMAHKGQPTVILAHTIKGYTLGKHFEGRNATHQMKKLTLDDL 480 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD QRIP+SDA+LE++PYLPPYYHPG ++PEI+YML RR+ALGGF+P RRT + L Sbjct 481 KRFRDIQRIPISDAELEKDPYLPPYYHPGPDSPEIQYMLQRRKALGGFLPSRRTDAAPLP 540 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 P Y ++KGSG QEVATTMA VR KE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 541 QPADKTYDVVRKGSGKQEVATTMAVVRILKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 600 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNRNGQLYT+VDA+LMLAYKES VGQILHEGINEAGS SF A GTSYATH EPMI Sbjct 601 SLKIYNRNGQLYTSVDAELMLAYKESTVGQILHEGINEAGSTSSFTAVGTSYATHGEPMI 660 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA+TNP Sbjct 661 PVYIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNP 720 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENP-------ENIFFYITVYNEPYVQPPEPENFD 711 A V+YDP+F+YEIA+IV+ GL RM G P ENIF+Y+TVYNEPY QP EPEN D Sbjct 721 AAVSYDPSFSYEIAHIVKDGLRRMYGGTPGVDGFGGENIFYYLTVYNEPYQQPAEPENLD 780 Query 712 PEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL 771 EG+L+GIY Y A E +AQIL SGV MP LRA ++LA EW VAADVWSVTSWGEL Sbjct 781 VEGLLKGIYLYKPA-EGSGPRAQILVSGVTMPDGLRAQRLLADEWGVAADVWSVTSWGEL 839 Query 772 NRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTL 831 RDGV E E L +P A PYVT+AL A+GP +A SDWMRAVP+QIR WVPG+Y TL Sbjct 840 RRDGVECEREALHNPGADAPTPYVTKALSQAQGPFVAASDWMRAVPDQIRQWVPGSYTTL 899 Query 832 GTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAP 891 GTDGFGFSDTRPAARR+FN DAES VVAVL ALA GE+D S V AA +YRIDDV AAP Sbjct 900 GTDGFGFSDTRPAARRFFNVDAESIVVAVLSALAKSGEVDRSKAVEAAARYRIDDVLAAP 959 Query 892 EQTTDPG 898 DPG Sbjct 960 VSMADPG 966 >gi|226360334|ref|YP_002778112.1| pyruvate dehydrogenase subunit E1 [Rhodococcus opacus B4] gi|226238819|dbj|BAH49167.1| pyruvate dehydrogenase E1 component [Rhodococcus opacus B4] Length=915 Score = 1490 bits (3857), Expect = 0.0, Method: Compositional matrix adjust. Identities = 727/907 (81%), Positives = 793/907 (88%), Gaps = 10/907 (1%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ET+EWLESFD LL R GP+RARYLMLR+LERAGE+ VA+PALTSTDYVN Sbjct 8 VASYLPDIDPDETTEWLESFDGLLDRSGPTRARYLMLRMLERAGEKHVALPALTSTDYVN 67 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE+VERRYRA+IRWNAA+MV RAQRPGVGVGGHISTYASSAALYEVGF Sbjct 68 TIPTENEPWFPGDEEVERRYRAFIRWNAAVMVTRAQRPGVGVGGHISTYASSAALYEVGF 127 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV--GGGLPSY 178 NHFFRGK HPGGGDQ+FIQGHASPGIYARAFLEGR+ AE++DGFRQEHSH GGGLPSY Sbjct 128 NHFFRGKDHPGGGDQIFIQGHASPGIYARAFLEGRIPAERMDGFRQEHSHTDSGGGLPSY 187 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+PDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDT+DQHVW FLGDGEMDEPE Sbjct 188 PHPRLLPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTADQHVWAFLGDGEMDEPE 247 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGLAHV A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE Sbjct 248 SRGLAHVAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 307 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGALVNLMN TPDGDYQTYKANDGGYVR+HFFGRDPRTK LV N+SD+DIW Sbjct 308 WDALLHADRDGALVNLMNVTPDGDYQTYKANDGGYVREHFFGRDPRTKELVANLSDRDIW 367 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRK+YAAY AA+ HKGQPTVILA TIKGY LGKHFEGRNATHQMKKLTL+DL Sbjct 368 NLKRGGHDYRKIYAAYAAAMAHKGQPTVILAHTIKGYTLGKHFEGRNATHQMKKLTLDDL 427 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD QRIP+SDA+LE +P +PPYYHPG +APEIRYMLDRR+ALGGF+PERRT + L Sbjct 428 KNFRDLQRIPISDAELERDPKMPPYYHPGPDAPEIRYMLDRRKALGGFLPERRTSPQPLP 487 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 P Y ++KGSG Q+VATTMA VR KE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 488 QPADSTYDVVRKGSGKQQVATTMALVRIMKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 547 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNRNGQLYTAVDA+LMLAYKESE+GQILHEGINEAGS SF A GTSYATH EPMI Sbjct 548 SLKIYNRNGQLYTAVDAELMLAYKESEIGQILHEGINEAGSTASFTAVGTSYATHGEPMI 607 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA+TNP Sbjct 608 PLYIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNP 667 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENP-------ENIFFYITVYNEPYVQPPEPENFD 711 A VAYDP+F+YE+A+IV+ GL RM G E+IF+YIT+YNEPY QP EPEN + Sbjct 668 AAVAYDPSFSYELAHIVKDGLRRMYGGTDGVDGFGGEDIFYYITLYNEPYTQPAEPENLN 727 Query 712 PEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL 771 +G+L+G+Y + +E KAQIL SGV MP LRA QMLA EW VAADVWSVTSWGEL Sbjct 728 VQGLLKGMYLFK-KSEASGPKAQILVSGVTMPDGLRAQQMLADEWGVAADVWSVTSWGEL 786 Query 772 NRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTL 831 RDG+ E + LR P A +PYVT+AL +A GP +A SDWMRAV +QIR WVPG+Y TL Sbjct 787 RRDGIESERQALRDPGTDAPLPYVTQALSDAAGPFVAASDWMRAVADQIRQWVPGSYTTL 846 Query 832 GTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAP 891 GTDGFGFSDTRPAARRYFN DAES VVAVL ALAG+G +D S V AA +YRIDDV AA Sbjct 847 GTDGFGFSDTRPAARRYFNVDAESIVVAVLSALAGEGTLDRSKAVDAATKYRIDDVRAAA 906 Query 892 EQTTDPG 898 TD G Sbjct 907 VSYTDTG 913 >gi|226307157|ref|YP_002767117.1| pyruvate dehydrogenase E1 component [Rhodococcus erythropolis PR4] gi|226186274|dbj|BAH34378.1| pyruvate dehydrogenase E1 component [Rhodococcus erythropolis PR4] Length=951 Score = 1488 bits (3851), Expect = 0.0, Method: Compositional matrix adjust. Identities = 724/907 (80%), Positives = 789/907 (87%), Gaps = 10/907 (1%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ET+EWLESFD LL R GP+RARYLMLR+LERAGE+ VA+PALTSTDYVN Sbjct 44 VASYLPDIDPDETTEWLESFDGLLDRSGPTRARYLMLRMLERAGEKHVALPALTSTDYVN 103 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE+VERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 104 TIPTENEPWFPGDEEVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 163 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV--GGGLPSY 178 NHFFRGK HPGGGD +FIQGHASPGIYARAFLEGR+ AEQLDGFRQE SH GG LPSY Sbjct 164 NHFFRGKDHPGGGDHIFIQGHASPGIYARAFLEGRIPAEQLDGFRQEKSHADFGGALPSY 223 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+PDFWEFPTVSMGLGP+NAIYQARFNHYL+DRGIKDT+DQHVW FLGDGEMDEPE Sbjct 224 PHPRLLPDFWEFPTVSMGLGPMNAIYQARFNHYLNDRGIKDTTDQHVWAFLGDGEMDEPE 283 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGLAHV A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE Sbjct 284 SRGLAHVAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 343 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGALVNLMN TPDGDYQTYKANDG +VRDHFFGRDPRTK LV++++DQ+IW Sbjct 344 WDALLHADRDGALVNLMNVTPDGDYQTYKANDGAFVRDHFFGRDPRTKELVKDLTDQEIW 403 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRKV+AAY AA+ HKGQPTVILA TIKGY LGKHFEGRNATHQMKKLTL+DL Sbjct 404 NLKRGGHDYRKVHAAYAAAMAHKGQPTVILAHTIKGYTLGKHFEGRNATHQMKKLTLDDL 463 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD Q IP+SDA+LE++PYLPPYYHPG +APEI+YMLDRR+ALGGF+P R T + L Sbjct 464 KAFRDMQHIPISDAELEKDPYLPPYYHPGADAPEIKYMLDRRKALGGFLPSRNTDAAPLK 523 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 LP Y ++KGSG QEVATTMA VR KE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 524 LPEDKTYDVIRKGSGKQEVATTMAIVRILKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 583 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNRNGQLYT+VDA+LMLAYKES +GQILHEGINEAGS SF A GTSYATH EPMI Sbjct 584 SLKIYNRNGQLYTSVDAELMLAYKESPIGQILHEGINEAGSTASFTAVGTSYATHGEPMI 643 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA+TNP Sbjct 644 PLYIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNP 703 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENP-------ENIFFYITVYNEPYVQPPEPENFD 711 A V YD AF+YE+A+IV+ GL RM G ENIF+Y+T+YNEPYVQP EPE D Sbjct 704 AAVTYDAAFSYELAHIVKDGLRRMYGGTEGVDGFGGENIFYYLTIYNEPYVQPAEPEGLD 763 Query 712 PEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL 771 EG+L+GIY Y +E KAQIL SGVAMP LRA ++LA EW V+ADVWSVTSWGEL Sbjct 764 VEGLLKGIYLYK-TSEAAGPKAQILVSGVAMPEGLRAQKLLADEWGVSADVWSVTSWGEL 822 Query 772 NRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTL 831 R+GV E + L +P A VP+VT AL +A+GPV+A SDWMRAV +QIR WVPG Y TL Sbjct 823 RREGVECERQALLNPSEDAPVPFVTTALSSAQGPVVAASDWMRAVSDQIRQWVPGDYTTL 882 Query 832 GTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAP 891 GTDGFGFSDTR AARRYFN DAES VVAVL LA +G I+ S V AA +YRIDDV AAP Sbjct 883 GTDGFGFSDTRTAARRYFNVDAESIVVAVLIGLAKEGSIERSKAVEAASRYRIDDVNAAP 942 Query 892 EQTTDPG 898 EQT D G Sbjct 943 EQTGDTG 949 >gi|226361706|ref|YP_002779484.1| 2-oxoacid dehydrogenase subunit E1 [Rhodococcus opacus B4] gi|226240191|dbj|BAH50539.1| pyruvate dehydrogenase E1 component [Rhodococcus opacus B4] Length=947 Score = 1487 bits (3850), Expect = 0.0, Method: Compositional matrix adjust. Identities = 726/919 (79%), Positives = 794/919 (87%), Gaps = 21/919 (2%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ET+EWLESFD LL R GP+RARYLMLR+LERAGE+ VA+PALTSTDYVN Sbjct 27 VASYLPDIDPDETTEWLESFDGLLDRSGPTRARYLMLRMLERAGEKHVALPALTSTDYVN 86 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE+VERRYRA+IRWNAA+MV RAQRPGVGVGGHISTYASSAALYEVGF Sbjct 87 TIPTENEPWFPGDEEVERRYRAFIRWNAAVMVTRAQRPGVGVGGHISTYASSAALYEVGF 146 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV--GGGLPSY 178 NHFFRGK HPGGGDQ+FIQGHASPGIYARAFLEGR+ AE++DGFRQEHSH GGGLPSY Sbjct 147 NHFFRGKDHPGGGDQIFIQGHASPGIYARAFLEGRIPAERMDGFRQEHSHTDSGGGLPSY 206 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+PDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDT+DQHVW FLGDGEMDEPE Sbjct 207 PHPRLLPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTADQHVWAFLGDGEMDEPE 266 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGLAHV A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE Sbjct 267 SRGLAHVAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 326 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGALVNLMN TPDGDYQTYKANDGGYVR+HFFGRDPRTK LV N+SD+DIW Sbjct 327 WDALLHADRDGALVNLMNVTPDGDYQTYKANDGGYVREHFFGRDPRTKELVANLSDRDIW 386 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRK+YAAY AA+ HKGQPTVILA TIKGY LGKHFEGRNATHQMKKLTL+DL Sbjct 387 NLKRGGHDYRKIYAAYAAAMAHKGQPTVILAHTIKGYTLGKHFEGRNATHQMKKLTLDDL 446 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD QRIP+SDA+LE +P +PPYYHPG +APEIRYMLDRR+ALGGF+PERRT + L Sbjct 447 KNFRDLQRIPISDAELERDPKMPPYYHPGPDAPEIRYMLDRRKALGGFLPERRTSPQPLP 506 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 P Y ++KGSG Q+VATTMA VR KE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 507 QPADSTYDVVRKGSGKQQVATTMALVRIMKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 566 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNRNGQLYTAVDA+LMLAYKESE+GQILHEGINEAGS SF A GTSYATH EPMI Sbjct 567 SLKIYNRNGQLYTAVDAELMLAYKESEIGQILHEGINEAGSTASFTAVGTSYATHGEPMI 626 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA+TNP Sbjct 627 PLYIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNP 686 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENP-------ENIFFYITVYNEPYVQPPEPENFD 711 A VAYDP+F+YE+A+IV+ GL RM G E+IF+YIT+YNEPY QP EPEN + Sbjct 687 AAVAYDPSFSYELAHIVKDGLRRMYGGTDGVDGFGGEDIFYYITLYNEPYTQPAEPENLN 746 Query 712 PEGVLRGIYRYHAA------------TEQRTNKAQILASGVAMPAALRAAQMLAAEWDVA 759 +G+L+G+Y + + + T +AQIL SGV MP LRA QMLA EW VA Sbjct 747 VQGLLKGMYLFRKSEASGSSVQSDGHSAGSTPRAQILVSGVTMPEGLRAQQMLADEWGVA 806 Query 760 ADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQ 819 ADVWSVTSWGEL RDG+ E + LR P A +PYVT+AL +A GP +A SDWMRAV +Q Sbjct 807 ADVWSVTSWGELRRDGIESERQALRDPGTDAPLPYVTQALSDAAGPFVAASDWMRAVADQ 866 Query 820 IRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAA 879 IR WVPG+Y TLGTDGFGFSDTRPAARRYFN DAES VVAVL ALAG+G +D S V AA Sbjct 867 IRQWVPGSYTTLGTDGFGFSDTRPAARRYFNVDAESIVVAVLSALAGEGTLDRSKAVDAA 926 Query 880 RQYRIDDVAAAPEQTTDPG 898 +YRIDDV AA TD G Sbjct 927 TKYRIDDVRAAAVSYTDTG 945 >gi|229490290|ref|ZP_04384132.1| pyruvate dehydrogenase (acetyl-transferring), homodimeric type [Rhodococcus erythropolis SK121] gi|229322822|gb|EEN88601.1| pyruvate dehydrogenase (acetyl-transferring), homodimeric type [Rhodococcus erythropolis SK121] Length=951 Score = 1486 bits (3847), Expect = 0.0, Method: Compositional matrix adjust. Identities = 723/907 (80%), Positives = 788/907 (87%), Gaps = 10/907 (1%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ET+EWLESFD LL R GP+RARYLMLR+LERAGE+ VA+PALTSTDYVN Sbjct 44 VASYLPDIDPDETTEWLESFDGLLDRSGPTRARYLMLRMLERAGEKHVALPALTSTDYVN 103 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE+VERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 104 TIPTENEPWFPGDEEVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 163 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV--GGGLPSY 178 NHFFRGK HPGGGD +FIQGHASPGIYARAFLEGR+ AEQLDGFRQE SH GG LPSY Sbjct 164 NHFFRGKDHPGGGDHIFIQGHASPGIYARAFLEGRIPAEQLDGFRQEKSHADFGGALPSY 223 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+PDFWEFPTVSMGLGP+NAIYQARFNHYL+DRGIKDT+DQHVW FLGDGEMDEPE Sbjct 224 PHPRLLPDFWEFPTVSMGLGPMNAIYQARFNHYLNDRGIKDTTDQHVWAFLGDGEMDEPE 283 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGLAHV A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE Sbjct 284 SRGLAHVAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 343 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGALVNLMN TPDGDYQTYKANDG +VRDHFFGRDPRTK LV++++DQ+IW Sbjct 344 WDALLHADRDGALVNLMNVTPDGDYQTYKANDGAFVRDHFFGRDPRTKELVKDLTDQEIW 403 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRKV+AAY AA+ HKGQPTVILA TIKGY LGKHFEGRNATHQMKKLTL+DL Sbjct 404 NLKRGGHDYRKVHAAYAAAMAHKGQPTVILAHTIKGYTLGKHFEGRNATHQMKKLTLDDL 463 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD Q IP+SDA+LE++PYLPPYYHPG +APEI+YMLDRR+ALGGF+P R T + L Sbjct 464 KAFRDMQHIPISDAELEKDPYLPPYYHPGADAPEIKYMLDRRKALGGFLPSRNTDAAPLK 523 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 LP Y ++KGSG QEVATTMA VR KE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 524 LPEDKTYDVIRKGSGKQEVATTMAIVRILKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 583 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNRNGQLYT+VDA+LMLAYKES +GQILHEGINEAGS SF A GTSYATH EPMI Sbjct 584 SLKIYNRNGQLYTSVDAELMLAYKESPIGQILHEGINEAGSTASFTAVGTSYATHGEPMI 643 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA+TNP Sbjct 644 PLYIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNP 703 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENP-------ENIFFYITVYNEPYVQPPEPENFD 711 A V YD AF+YE+A+IV+ GL RM G ENIF+Y+T+YNEPYVQP EPE D Sbjct 704 AAVTYDAAFSYELAHIVKDGLRRMYGGTEGVDGFGGENIFYYLTIYNEPYVQPAEPEGLD 763 Query 712 PEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL 771 EG+L+GIY Y +E KAQIL SGVAMP LRA ++L EW V+ADVWSVTSWGEL Sbjct 764 VEGLLKGIYLYK-TSEAAGPKAQILVSGVAMPEGLRAQKLLVDEWGVSADVWSVTSWGEL 822 Query 772 NRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTL 831 R+GV E + L +P A VP+VT AL +A+GPV+A SDWMRAV +QIR WVPG Y TL Sbjct 823 RREGVECERQALLNPSEDAPVPFVTTALSSAQGPVVAASDWMRAVSDQIRQWVPGDYTTL 882 Query 832 GTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAP 891 GTDGFGFSDTR AARRYFN DAES VVAVL LA +G I+ S V AA +YRIDDV AAP Sbjct 883 GTDGFGFSDTRTAARRYFNVDAESIVVAVLIGLAKEGSIERSKAVEAASRYRIDDVNAAP 942 Query 892 EQTTDPG 898 EQT D G Sbjct 943 EQTGDTG 949 >gi|111018209|ref|YP_701181.1| pyruvate dehydrogenase subunit E1 [Rhodococcus jostii RHA1] gi|110817739|gb|ABG93023.1| pyruvate dehydrogenase E1 component [Rhodococcus jostii RHA1] Length=951 Score = 1484 bits (3843), Expect = 0.0, Method: Compositional matrix adjust. Identities = 724/907 (80%), Positives = 792/907 (88%), Gaps = 10/907 (1%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ET+EWLESFD LL R GP+RARYLMLR+LERAGE+ VA+PALTSTDYVN Sbjct 44 VASYLPDIDPDETTEWLESFDGLLDRSGPTRARYLMLRMLERAGEKHVALPALTSTDYVN 103 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE+ ERRYRA+IRWNAA+MV RAQRPGVGVGGHISTYASSAALYEVGF Sbjct 104 TIPTENEPWFPGDEETERRYRAFIRWNAAVMVTRAQRPGVGVGGHISTYASSAALYEVGF 163 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV--GGGLPSY 178 NHFFRGK HPGGGDQ+FIQGHASPGIYARAFLEGR+ AE++DGFRQEHSH GGGLPSY Sbjct 164 NHFFRGKDHPGGGDQIFIQGHASPGIYARAFLEGRIPAERMDGFRQEHSHADQGGGLPSY 223 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+PDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDT+DQHVW FLGDGEMDEPE Sbjct 224 PHPRLLPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTADQHVWAFLGDGEMDEPE 283 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGLAHV A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE Sbjct 284 SRGLAHVAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 343 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGALVNLMN TPDGDYQTYKANDGGYVR+HFFGRDPRTK LV N+SDQDIW Sbjct 344 WDALLHADRDGALVNLMNVTPDGDYQTYKANDGGYVREHFFGRDPRTKELVANLSDQDIW 403 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRK+YAAY AA+ HKGQPTVILA TIKGY LGKHFEGRNATHQMKKLTL+DL Sbjct 404 NLKRGGHDYRKIYAAYAAAMAHKGQPTVILAHTIKGYTLGKHFEGRNATHQMKKLTLDDL 463 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD QRIP+SDA+LE++P +PPYYHPG +APEI+YMLDRRRALGGF+P+RRT L Sbjct 464 KNFRDLQRIPISDAELEKDPKMPPYYHPGPDAPEIQYMLDRRRALGGFLPQRRTSPAPLP 523 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 +P Y ++KGSG Q+VATTMA VR KE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 524 MPPDSTYDVVRKGSGKQQVATTMALVRIMKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 583 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNRNGQLYTAVDADLMLAYKESE+GQILHEGINEAGS SF A GTSYATH EPMI Sbjct 584 SLKIYNRNGQLYTAVDADLMLAYKESEIGQILHEGINEAGSTASFTAVGTSYATHGEPMI 643 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA+TNP Sbjct 644 PLYIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNP 703 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENP-------ENIFFYITVYNEPYVQPPEPENFD 711 A VAYDPAF+YEIA+IV+ GL RM G E+IF+YIT+YNEPY QP EP + + Sbjct 704 AAVAYDPAFSYEIAHIVKDGLRRMYGGTDGVDGFGGEDIFYYITLYNEPYSQPAEPADLN 763 Query 712 PEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGEL 771 +G+L+G+Y + ++ KAQIL SGV MP LRA ++LA EW VAADVWSVTSWGEL Sbjct 764 VDGLLKGMYLFK-KSQASGPKAQILVSGVTMPEGLRAQELLADEWGVAADVWSVTSWGEL 822 Query 772 NRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTL 831 RDG+ E + LR P A +PYVT+AL +A GP +A SDWMRAV +QIR WVPG+Y TL Sbjct 823 RRDGIESERQALRDPGTDAPLPYVTQALSDAAGPFVAASDWMRAVADQIRQWVPGSYTTL 882 Query 832 GTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAP 891 GTDGFGFSDTRPAARRYFN DAES VVAVL ALAG+G +D S V AA +YRIDDV AA Sbjct 883 GTDGFGFSDTRPAARRYFNVDAESIVVAVLSALAGEGTLDRSKAVEAANRYRIDDVRAAA 942 Query 892 EQTTDPG 898 TD G Sbjct 943 VSYTDTG 949 >gi|333918898|ref|YP_004492479.1| pyruvate dehydrogenase E1 component [Amycolicicoccus subflavus DQS3-9A1] gi|333481119|gb|AEF39679.1| Pyruvate dehydrogenase E1 component [Amycolicicoccus subflavus DQS3-9A1] Length=921 Score = 1484 bits (3842), Expect = 0.0, Method: Compositional matrix adjust. Identities = 719/900 (80%), Positives = 790/900 (88%), Gaps = 3/900 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 + SYLPDIDPEETSEWLESFD +L R RYL+LRLLERA E+RVA+PALTSTDYVN Sbjct 21 ITSYLPDIDPEETSEWLESFDAMLSHSTSERGRYLLLRLLERANERRVALPALTSTDYVN 80 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 +IPTE EPWFPGDE+VERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 81 SIPTEREPWFPGDEEVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 140 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVG--GGLPSY 178 NHFFRGKSHPGGGD +FIQGHASPGIYARAFLEGRLT +QLDGFRQEHSH G GGLPSY Sbjct 141 NHFFRGKSHPGGGDSIFIQGHASPGIYARAFLEGRLTTDQLDGFRQEHSHAGEGGGLPSY 200 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMP+FWEFPTVSMGLGP+NAIYQARFNHYL DRG+KDTSDQHVW FLGDGEMDEPE Sbjct 201 PHPRLMPEFWEFPTVSMGLGPMNAIYQARFNHYLRDRGLKDTSDQHVWAFLGDGEMDEPE 260 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGL H+ A+EGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKV+WGRE Sbjct 261 SRGLVHIAAMEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVIWGRE 320 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WD+L +AD+DGALVNLMNTTPDGD+QTYKANDG YVR+HFFGRDPRTK LV N+SD DIW Sbjct 321 WDSLFYADKDGALVNLMNTTPDGDFQTYKANDGSYVREHFFGRDPRTKELVNNLSDADIW 380 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRKVYAAY+AA HKGQPTVILA TIKGY LG HFEGRNATHQMKKL L+DL Sbjct 381 NLKRGGHDYRKVYAAYKAATSHKGQPTVILAHTIKGYQLGTHFEGRNATHQMKKLALDDL 440 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K+FRD QRIP++D QLE +PYLPPYYHPG +APEI YML+RR+ LGGF+P+RR K+ L Sbjct 441 KQFRDRQRIPITDEQLENDPYLPPYYHPGEDAPEIEYMLERRKQLGGFLPQRRNKATVLE 500 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 LPG YA ++KGSG QE+ATTMA VR FKE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 501 LPGDKAYATVRKGSGKQEIATTMAVVRLFKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 560 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNR+GQLYT+VDA+LMLAYKESE+GQILHEGINEAGS GSFIAAGTSY+TH+EPMI Sbjct 561 SLKIYNRHGQLYTSVDAELMLAYKESEIGQILHEGINEAGSTGSFIAAGTSYSTHDEPMI 620 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHS LA TNP Sbjct 621 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSHTLAGTNP 680 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRG 718 A VAYDPAFA+EIA+IV+ GL RM G +PENIF+YIT+YNEPY QP EP++ D + +LRG Sbjct 681 ACVAYDPAFAFEIAHIVKDGLRRMYGPDPENIFYYITIYNEPYSQPAEPKDLDVDSLLRG 740 Query 719 IYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAI 778 +YRY A + + +KA IL SGVA+P ALRA ++LA EWDVAADVWSVTSW EL RDG Sbjct 741 LYRYAKAGKGK-HKASILVSGVAVPWALRAQEILAKEWDVAADVWSVTSWTELRRDGRRC 799 Query 779 ETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGF 838 E E LR P +VT AL+ + GP + VSDW AVP+QIR WVPG Y+TLG DGFGF Sbjct 800 EDEALRDPSGKKREAHVTTALKKSEGPFVGVSDWESAVPDQIRTWVPGHYVTLGADGFGF 859 Query 839 SDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 SDTRPAARRYFN D+ES VV VL ALA +G ID V AA +YRIDDVAAAPEQT+DPG Sbjct 860 SDTRPAARRYFNIDSESIVVGVLNALADEGTIDRDVAAKAAAEYRIDDVAAAPEQTSDPG 919 >gi|54023581|ref|YP_117823.1| pyruvate dehydrogenase subunit E1 [Nocardia farcinica IFM 10152] gi|54015089|dbj|BAD56459.1| putative pyruvate dehydrogenase E1 component [Nocardia farcinica IFM 10152] Length=927 Score = 1483 bits (3840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 726/918 (80%), Positives = 793/918 (87%), Gaps = 27/918 (2%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +ASYLPDIDPEET EWLESFD +L R GP RARYLMLRLLERAGE+RV+IP+LTSTDYVN Sbjct 1 MASYLPDIDPEETGEWLESFDEMLDREGPQRARYLMLRLLERAGERRVSIPSLTSTDYVN 60 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE+VERRYRAWIRWNAAIMVHRAQRPG+GVGGHISTYASSAALYEVGF Sbjct 61 TIPTENEPWFPGDEEVERRYRAWIRWNAAIMVHRAQRPGIGVGGHISTYASSAALYEVGF 120 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSH--VGGGLPSY 178 NHFFRGK HPGGGDQ+FIQGHASPGIYARAFLEGRLTA+QLDGFRQE+SH +G GLPSY Sbjct 121 NHFFRGKDHPGGGDQIFIQGHASPGIYARAFLEGRLTADQLDGFRQEYSHGGLGHGLPSY 180 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+ +FWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDTSDQHVW FLGDGEMDEPE Sbjct 181 PHPRLLNNFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSDQHVWAFLGDGEMDEPE 240 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGLAHV A+EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELE+FFRGAGWNVIKV+WGRE Sbjct 241 SRGLAHVAAMEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELEAFFRGAGWNVIKVIWGRE 300 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALL ADRDGALVNLMN+TPDGDYQTYKANDG YVRDHFFGRDPRTKALV+NMSDQ+IW Sbjct 301 WDALLGADRDGALVNLMNSTPDGDYQTYKANDGAYVRDHFFGRDPRTKALVQNMSDQEIW 360 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRKVYAAY AA+ HKGQPTVILAKTIKGY LGKHFEGRNATHQMKKLTL+DL Sbjct 361 NLKRGGHDYRKVYAAYAAAMAHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKLTLQDL 420 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K+FRD QRIP+SDA+LE++PYLPPYYHPG+ A EI+YMLDRRRALGGF+PERR K+K L Sbjct 421 KDFRDLQRIPISDAELEKDPYLPPYYHPGMEAREIQYMLDRRRALGGFLPERRAKAKPLQ 480 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 LPG + Y ++KGSG Q VATTMA VR KE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 481 LPGDEAYRSVRKGSGKQNVATTMALVRLMKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 540 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNRNGQLYT+VDA+LMLAYKES VGQILHEGINEAGS SF AAGTSYATH EPMI Sbjct 541 SLKIYNRNGQLYTSVDAELMLAYKESTVGQILHEGINEAGSTASFTAAGTSYATHGEPMI 600 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQ+ARGFVLGATAGRTTLTGEGLQH DGHSLLLA+TNP Sbjct 601 PLYIFYSMFGFQRTGDGLWAAADQLARGFVLGATAGRTTLTGEGLQHNDGHSLLLASTNP 660 Query 659 AVVAYDPAFAYEIAYIVESGLARMCG-----------------ENP-------ENIFFYI 694 AVV YDPAFA+EIA+IV GL RM G E P E++F+YI Sbjct 661 AVVTYDPAFAFEIAHIVRDGLRRMYGGGRPPAHQAVLPGTEPVERPDTDTFGGEDVFYYI 720 Query 695 TVYNEPYVQPPEPENFDPEGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAA 754 T+YNEPY QP EPEN D EG+L+GIYRY AA E +AQIL SGV +P LRA +LA Sbjct 721 TLYNEPYQQPAEPENLDVEGLLKGIYRYRAAGEGEL-RAQILVSGVTVPDGLRAQALLAE 779 Query 755 EWDVAADVWSVTSWGELNRDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMR 814 EW V ADVWSVTSWGEL ++ +A E LR P G PY+T L A GP +A +DWMR Sbjct 780 EWGVQADVWSVTSWGELRKEALAKEIAALRDPGADVGTPYITEVLSAAGGPFVAATDWMR 839 Query 815 AVPEQIRPWVPGTYLTLGTDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSV 874 AVP+Q+R WVPG ++TLGTDGFGFSDTRPAARR FN DA+S VAVLE LA G+ID S Sbjct 840 AVPDQVRQWVPGEFITLGTDGFGFSDTRPAARRVFNVDAQSIAVAVLEGLARTGKIDRSK 899 Query 875 PVAAARQYRIDDVAAAPE 892 V AAR+YRI DV AAP+ Sbjct 900 AVEAARKYRIGDVDAAPK 917 >gi|343924115|ref|ZP_08763678.1| pyruvate dehydrogenase E1 component [Gordonia alkanivorans NBRC 16433] gi|343765920|dbj|GAA10604.1| pyruvate dehydrogenase E1 component [Gordonia alkanivorans NBRC 16433] Length=960 Score = 1473 bits (3813), Expect = 0.0, Method: Compositional matrix adjust. Identities = 700/900 (78%), Positives = 783/900 (87%), Gaps = 2/900 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ET+EWL+SFD LL GP RARYLMLRLLERAGE+RV+IPALTSTDYVN Sbjct 59 VASYLPDIDPDETTEWLDSFDALLDAAGPGRARYLMLRLLERAGEKRVSIPALTSTDYVN 118 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE+VERR+R IRWNAAIMVHRAQRPGVGVGGHISTYASSA+LYEVGF Sbjct 119 TIPTEAEPWFPGDEEVERRFRQMIRWNAAIMVHRAQRPGVGVGGHISTYASSASLYEVGF 178 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVG--GGLPSY 178 NHFFRGK+H GGGD +FIQGHASPGIYARA+LEGR+ ++DGFRQEHSH G GGLPSY Sbjct 179 NHFFRGKNHSGGGDHIFIQGHASPGIYARAYLEGRIDEARMDGFRQEHSHAGEGGGLPSY 238 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMPDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDTSDQHVW FLGDGEMDEPE Sbjct 239 PHPRLMPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSDQHVWAFLGDGEMDEPE 298 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRG A A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKV+WGRE Sbjct 299 SRGFASFAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVIWGRE 358 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGALVNLMNTTPDGD+QTYKANDG +VR+HFF RDPRTK LV+++SD +IW Sbjct 359 WDALLHADRDGALVNLMNTTPDGDFQTYKANDGAFVREHFFNRDPRTKELVKDLSDAEIW 418 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRK++AAY AA+ HKGQPTVILA TIKGY LGKHFEGRNATHQMKKLTL+DL Sbjct 419 NLKRGGHDYRKIHAAYAAAMTHKGQPTVILAHTIKGYTLGKHFEGRNATHQMKKLTLDDL 478 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD+ RIP+SD QLE++PYLPPYYHPG ++PE++YMLDRR+ LGGF+P RRTK+K L Sbjct 479 KAFRDSTRIPISDEQLEKDPYLPPYYHPGKDSPELQYMLDRRKTLGGFLPSRRTKAKVLE 538 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 +KGSG Q+VATTMA VR FK++LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 539 ADTSSALKTTEKGSGKQQVATTMALVRVFKDLLRDKEIGKRIVPIIPDEARTFGMDSWFP 598 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 +LKIYNRNGQLYT+VDA+LMLAYKES GQILHEGINEAGS SF A GTSYATH+EPMI Sbjct 599 TLKIYNRNGQLYTSVDAELMLAYKESSEGQILHEGINEAGSAASFAAVGTSYATHDEPMI 658 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGDSFWAAADQMARGFV+GATAGRTTLTGEGLQHADGHS LLAATNP Sbjct 659 PLYIFYSMFGFQRTGDSFWAAADQMARGFVIGATAGRTTLTGEGLQHADGHSPLLAATNP 718 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRG 718 AVVAYDPAFAYE+ +IV+ GL RM GE+PEN+F+YITVYNEP QP +PE+ D EG+++G Sbjct 719 AVVAYDPAFAYELGHIVDDGLKRMYGEDPENVFYYITVYNEPISQPAKPEHVDHEGIVKG 778 Query 719 IYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAI 778 Y + A E + A IL SG+ MP ALRA+++LA EW+V ADV+SVTSW EL RDG+ Sbjct 779 GYLFQKAPENKEYPANILVSGITMPDALRASELLAEEWNVGADVYSVTSWSELARDGIRA 838 Query 779 ETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGF 838 + + LR P Y+T + +A GP + VSD+MR V EQIR ++PGTYLTLGTDGFGF Sbjct 839 DRQALRDPGSEPAPAYLTELMADAAGPFVGVSDYMRGVQEQIRAYLPGTYLTLGTDGFGF 898 Query 839 SDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 SDTRPAARR+FN DAES VVAVL ALA DG I SV AA +Y+IDDVAAAPEQT+DPG Sbjct 899 SDTRPAARRFFNVDAESIVVAVLVALARDGHIAMSVAKQAADKYQIDDVAAAPEQTSDPG 958 >gi|111019557|ref|YP_702529.1| 2-oxoacid dehydrogenase subunit E1 [Rhodococcus jostii RHA1] gi|110819087|gb|ABG94371.1| pyruvate dehydrogenase E1 component [Rhodococcus jostii RHA1] Length=1015 Score = 1468 bits (3800), Expect = 0.0, Method: Compositional matrix adjust. Identities = 725/964 (76%), Positives = 793/964 (83%), Gaps = 66/964 (6%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDP+ET+EWLESFD LL R GP+RARYLMLR+LERAGE+ VA+PALTSTDYVN Sbjct 50 VASYLPDIDPDETTEWLESFDGLLDRSGPTRARYLMLRMLERAGEKHVALPALTSTDYVN 109 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE+ ERRYRA+IRWNAA+MV RAQRPGVGVGGHISTYASSAALYEVGF Sbjct 110 TIPTENEPWFPGDEETERRYRAFIRWNAAVMVTRAQRPGVGVGGHISTYASSAALYEVGF 169 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHV--GGGLPSY 178 NHFFRGK HPGGGDQ+FIQGHASPGIYARAFLEGR+ AE++DGFRQEHSH GGGLPSY Sbjct 170 NHFFRGKDHPGGGDQIFIQGHASPGIYARAFLEGRIPAERMDGFRQEHSHADQGGGLPSY 229 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+PDFWEFPTVSMGLGP+NAIYQARFNHYLHDRGIKDT+DQHVW FLGDGEMDEPE Sbjct 230 PHPRLLPDFWEFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTADQHVWAFLGDGEMDEPE 289 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGLAHV A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE Sbjct 290 SRGLAHVAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 349 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGALVNLMN TPDGDYQTYKANDGGYVR+HFFGRDPRTK LV N+SDQDIW Sbjct 350 WDALLHADRDGALVNLMNVTPDGDYQTYKANDGGYVREHFFGRDPRTKELVANLSDQDIW 409 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRK+YAAY AA+ HKGQPTVILA TIKGY LGKHFEGRNATHQMKKLTL+DL Sbjct 410 NLKRGGHDYRKIYAAYAAAMAHKGQPTVILAHTIKGYTLGKHFEGRNATHQMKKLTLDDL 469 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD QRIP+SDA+LE++P +PPYYHPG +APEI+YMLDRRRALGGF+P+RRT L Sbjct 470 KNFRDLQRIPISDAELEKDPKMPPYYHPGPDAPEIQYMLDRRRALGGFLPQRRTSPAPLP 529 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 +P Y ++KGSG Q+VATTMA VR KE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 530 MPPDSTYDVVRKGSGKQQVATTMALVRIMKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 589 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNRNGQLYTAVDADLMLAYKESE+GQILHEGINEAGS SF A GTSYATH EPMI Sbjct 590 SLKIYNRNGQLYTAVDADLMLAYKESEIGQILHEGINEAGSTASFTAVGTSYATHGEPMI 649 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA+TNP Sbjct 650 PLYIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLASTNP 709 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENP------------ENIFFYITVYNEPYVQPPE 706 A VAYDPAF+YEIA+IV+ GL RM G P E+IF+YIT+YNEPY QP E Sbjct 710 AAVAYDPAFSYEIAHIVKDGLRRMYGGTPAADGTLKPGFGGEDIFYYITLYNEPYSQPAE 769 Query 707 PENFDPEGVLRGIYRY-------------------------------------------- 722 P + + EG+L+G+Y + Sbjct 770 PADLNVEGLLKGMYLFKKSQASGDSASNNGHSAGSAPQHGHSAGSAPQHGHSAGSAPQHA 829 Query 723 --------HAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRD 774 HA + +AQIL SGV MP LRA ++LA EW VAADVWSVTSWGEL RD Sbjct 830 HSAGSAPQHAHSAGSAPRAQILVSGVTMPEGLRAQELLADEWGVAADVWSVTSWGELRRD 889 Query 775 GVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTD 834 G+ E + LR P A +PYVT+AL +A GP +A SDWMRAV ++IR WVPG+Y TLGTD Sbjct 890 GIESERQALRDPGTDAPLPYVTQALSDAAGPFVAASDWMRAVADRIRQWVPGSYTTLGTD 949 Query 835 GFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQT 894 GFGFSDTRPAARRYFN DAES VVAVL ALAG+G +D S V AA +YRIDDV AA Sbjct 950 GFGFSDTRPAARRYFNVDAESIVVAVLSALAGEGTLDRSKAVEAANRYRIDDVRAAAVSY 1009 Query 895 TDPG 898 D G Sbjct 1010 ADTG 1013 >gi|296140416|ref|YP_003647659.1| 2-oxo-acid dehydrogenase E1 subunit, homodimeric type [Tsukamurella paurometabola DSM 20162] gi|296028550|gb|ADG79320.1| 2-oxo-acid dehydrogenase E1 subunit, homodimeric type [Tsukamurella paurometabola DSM 20162] Length=937 Score = 1446 bits (3743), Expect = 0.0, Method: Compositional matrix adjust. Identities = 691/900 (77%), Positives = 777/900 (87%), Gaps = 2/900 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEET EWLESFD L+ GP+RARYLMLRLLERA E RV+IP+LTSTDYVN Sbjct 36 VASYLPDIDPEETGEWLESFDDLIATHGPARARYLMLRLLERASENRVSIPSLTSTDYVN 95 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPT+LEPWFPGDE++ERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 96 TIPTDLEPWFPGDEEIERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 155 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSH--VGGGLPSY 178 NHFFRGK HPGGGDQVFIQGHASPGIYARAFLEGR+ AE++DGFRQE SH G GLPSY Sbjct 156 NHFFRGKEHPGGGDQVFIQGHASPGIYARAFLEGRIPAERMDGFRQEKSHEDKGKGLPSY 215 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+ +FWEFPTVSMGLGP+NAI QARFNHYLHDRGIKDTSDQHVW FLGDGEMDEPE Sbjct 216 PHPRLLSNFWEFPTVSMGLGPMNAIMQARFNHYLHDRGIKDTSDQHVWAFLGDGEMDEPE 275 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRG + A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKV+WGRE Sbjct 276 SRGQIQIAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVIWGRE 335 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WD LLH DRDGALVN+MNTTPDGDYQT+KANDG +VR+HFFGRDPRTK LV++M+D+ IW Sbjct 336 WDELLHKDRDGALVNIMNTTPDGDYQTFKANDGAFVREHFFGRDPRTKELVKDMTDEQIW 395 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 L+RGGHDYRKVYAAY++A++HKGQPTVILA TIKG+ LG +FEGRNATHQMKKLTL+DL Sbjct 396 GLRRGGHDYRKVYAAYKSAMEHKGQPTVILAHTIKGFGLGHNFEGRNATHQMKKLTLDDL 455 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K+FRD RIP++D +LE++PYLPPYY+PG + EI+YML+RR+ LGGF+P RRT+++ALT Sbjct 456 KQFRDELRIPITDEELEKDPYLPPYYNPGPESKEIQYMLERRKTLGGFLPARRTEAQALT 515 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 P ++KGSG Q+VATTMA VR FKE+LRD ++G RIVPIIPDEARTFGMDSWFP Sbjct 516 TPDITALDVMRKGSGKQQVATTMAVVRIFKELLRDPEVGHRIVPIIPDEARTFGMDSWFP 575 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNR GQ YT+VDA LMLAYKE+ G ILHEGINEAGS SF A GTSYATH+ PMI Sbjct 576 SLKIYNRLGQTYTSVDAQLMLAYKENPQGVILHEGINEAGSTASFTAVGTSYATHDVPMI 635 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQMARGFVLGATAGRTTLTGEGLQHADGHS +LA+TNP Sbjct 636 PLYIFYSMFGFQRTGDGLWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSHVLASTNP 695 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRG 718 AVVAYDPAF YE+A+IV GL RM GENPENI++Y+TVYNEP QP EPEN D EG+L+G Sbjct 696 AVVAYDPAFGYELAHIVIDGLRRMYGENPENIYYYVTVYNEPIHQPAEPENLDVEGLLKG 755 Query 719 IYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAI 778 +Y Y A+ KA ILASGV MP AL A ++LA EW V A V+SVTSW EL+RDG+ Sbjct 756 MYLYRPASAGHARKASILASGVTMPDALVAQELLAQEWGVDASVYSVTSWVELSRDGIEA 815 Query 779 ETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGF 838 E LR P PA P+VT+ L +A+GP +A SD+MR + IR WVPGTYLTLGTDGFGF Sbjct 816 EKAALRDPAAPARTPHVTKVLADAQGPTVAASDFMRGTQDLIRAWVPGTYLTLGTDGFGF 875 Query 839 SDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 SDTRPAARRYFN DA+S VV VL ALA DGE+D SV AA++YRIDDV AAP+QT+DPG Sbjct 876 SDTRPAARRYFNVDAQSIVVGVLLALARDGELDFSVAAEAAKRYRIDDVLAAPKQTSDPG 935 >gi|257055083|ref|YP_003132915.1| pyruvate dehydrogenase subunit E1 [Saccharomonospora viridis DSM 43017] gi|256584955|gb|ACU96088.1| pyruvate dehydrogenase E1 component, homodimeric type [Saccharomonospora viridis DSM 43017] Length=938 Score = 1434 bits (3711), Expect = 0.0, Method: Compositional matrix adjust. Identities = 695/905 (77%), Positives = 772/905 (86%), Gaps = 7/905 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +A++LPDIDPEET+EWL+SFD L R G RARYL+LR+LERA E+ V +P L++TDYVN Sbjct 32 LAAHLPDIDPEETAEWLDSFDAALARGGQQRARYLLLRMLERARERNVGVPPLSTTDYVN 91 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE++ERRYRA+IRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 92 TIPTENEPWFPGDEEIERRYRAFIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 151 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVG--GGLPSY 178 NHFFRGK+H GGGDQ+FIQGHASPGIYARAFLEGRLTAEQLDGFRQE SH G GGLPSY Sbjct 152 NHFFRGKNHSGGGDQIFIQGHASPGIYARAFLEGRLTAEQLDGFRQEISHAGEGGGLPSY 211 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMPDFWE+PTVSMGLGP+NAIYQARFN YLH RGIKDTSDQHVW FLGDGEMDEPE Sbjct 212 PHPRLMPDFWEYPTVSMGLGPMNAIYQARFNRYLHARGIKDTSDQHVWAFLGDGEMDEPE 271 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGL HV A EGLDNLTFVINCNLQRLDGPVRGNGKIIQELE+FFRGAGWNVIKV+WGRE Sbjct 272 SRGLIHVAAAEGLDNLTFVINCNLQRLDGPVRGNGKIIQELEAFFRGAGWNVIKVIWGRE 331 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGALVNLMN TPDGDYQTYKANDG YVR+HFFGRDPRTK LV +++D+ IW Sbjct 332 WDALLHADRDGALVNLMNQTPDGDYQTYKANDGAYVREHFFGRDPRTKELVAHLTDEQIW 391 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRKVYAAY+AA++H GQPTVILA TIKGY LG FEGRNATHQMKKLTL+DL Sbjct 392 NLKRGGHDYRKVYAAYKAAMEHHGQPTVILAHTIKGYGLGPAFEGRNATHQMKKLTLDDL 451 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD QRIP+SDA+LE +P LPPYYHPG ++PEI+YM RR+ALGG++PERR+ +K L Sbjct 452 KLFRDAQRIPISDAELERDPTLPPYYHPGEDSPEIQYMKGRRQALGGYLPERRSTAKPLV 511 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 LPG +Y ++KGSG Q+VATTMA VR +E+ +D +IG R+VPIIPDEARTFG+DS FP Sbjct 512 LPGDKVYEAIRKGSGKQDVATTMAVVRLIRELAKDPEIGHRLVPIIPDEARTFGLDSMFP 571 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 + KIYN +GQ YT+VDA LMLAYKESE GQ+LHEGINEAGS SF AAGTSYATH EPMI Sbjct 572 TAKIYNPHGQNYTSVDAQLMLAYKESEQGQLLHEGINEAGSTASFTAAGTSYATHGEPMI 631 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 PIYIFYSMFGFQRTGDS +AAADQMARGFVLGATAGRTTLTGEGLQHADGHS LLA TNP Sbjct 632 PIYIFYSMFGFQRTGDSLYAAADQMARGFVLGATAGRTTLTGEGLQHADGHSQLLATTNP 691 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGE-----NPENIFFYITVYNEPYVQPPEPENFDPE 713 VVAYDPA+A+EIA+IV+ GL RM GE N E++F+YITVYNEPY QPPEPEN D E Sbjct 692 GVVAYDPAWAFEIAHIVKDGLRRMYGETGRDGNGEDVFYYITVYNEPYQQPPEPENLDVE 751 Query 714 GVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNR 773 G+L+G+Y Y A KAQIL SGV MP ALRA +MLA EW V+ADVWS TSW EL R Sbjct 752 GLLKGLYLYQTAPNDIGPKAQILVSGVLMPEALRAQRMLAEEWGVSADVWSATSWSELRR 811 Query 774 DGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGT 833 + V ++ + HP VPYVT+ L NA GPV+AVSDWMRAVP+ IRPWVP LTLGT Sbjct 812 EAVEVDRDNFLHPADEPRVPYVTQKLSNAEGPVVAVSDWMRAVPDLIRPWVPTDMLTLGT 871 Query 834 DGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQ 893 DGFGFSDTRPAARRYF DAES V VL LA GEI V AAR+YRI DV+AA Q Sbjct 872 DGFGFSDTRPAARRYFLVDAESITVGVLTMLARRGEITQDTVVEAARKYRIHDVSAAGPQ 931 Query 894 TTDPG 898 T+DPG Sbjct 932 TSDPG 936 >gi|331695979|ref|YP_004332218.1| 2-oxo-acid dehydrogenase E1 subunit [Pseudonocardia dioxanivorans CB1190] gi|326950668|gb|AEA24365.1| 2-oxo-acid dehydrogenase E1 subunit, homodimeric type [Pseudonocardia dioxanivorans CB1190] Length=922 Score = 1422 bits (3681), Expect = 0.0, Method: Compositional matrix adjust. Identities = 679/900 (76%), Positives = 765/900 (85%), Gaps = 2/900 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +A++LPDIDPEET+EWL+SFD +L G RARYLMLR+L+RA E+ V +P+LTSTDYVN Sbjct 21 LAAHLPDIDPEETAEWLDSFDAVLDAAGQQRARYLMLRMLQRARERHVGVPSLTSTDYVN 80 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPT+ EPWFPGDE+ ER YR WIRWNAA+ VHRAQRPG+ VGGHIS+YASSA LYEVGF Sbjct 81 TIPTDREPWFPGDEEAERAYRRWIRWNAAMTVHRAQRPGISVGGHISSYASSATLYEVGF 140 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSH--VGGGLPSY 178 NHFFRGK HPGGGDQV+IQGHASPGIYARA+LEGRL+ ++LDGFRQE SH G GLPSY Sbjct 141 NHFFRGKEHPGGGDQVYIQGHASPGIYARAYLEGRLSEDRLDGFRQELSHGGPGHGLPSY 200 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMPDFWEFPTVSMGLGP+NAI QARFN YL DRGIKDTSDQ VW FLGDGEMDEPE Sbjct 201 PHPRLMPDFWEFPTVSMGLGPMNAIMQARFNRYLRDRGIKDTSDQRVWAFLGDGEMDEPE 260 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGL HV A EGLDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKV+WGRE Sbjct 261 SRGLIHVAATEGLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVIWGRE 320 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGAL+NLMN TPDGDYQTYKANDG +VR+HFFGRDPRTK LV ++SD IW Sbjct 321 WDALLHADRDGALINLMNQTPDGDYQTYKANDGAFVREHFFGRDPRTKDLVSDLSDAQIW 380 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRKVYAAY AA++H GQPTVILAKTIKGY LG HF GRNATHQMKKLTLEDL Sbjct 381 NLKRGGHDYRKVYAAYAAALEHNGQPTVILAKTIKGYGLGSHFAGRNATHQMKKLTLEDL 440 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K+FRD QRIP+SDA+LE +PYLPPYYHPG +APEIRYM DRR+ALGG +P RRT SKAL Sbjct 441 KQFRDEQRIPISDAELERDPYLPPYYHPGEDAPEIRYMADRRKALGGPLPSRRTSSKALV 500 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 LPG +Y +KGSG QE ATTMA VR +E+++DK+IGPR VPIIPDEARTFGMDS FP Sbjct 501 LPGDKVYEVARKGSGKQEAATTMAFVRILRELVKDKEIGPRFVPIIPDEARTFGMDSMFP 560 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 + KIYN +GQ YT+VDA LMLAYKESE GQ+LHEGINEAGSVGSF AAGTSYATH+EPMI Sbjct 561 TQKIYNPHGQQYTSVDASLMLAYKESEQGQLLHEGINEAGSVGSFTAAGTSYATHDEPMI 620 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+Y+FYSMFGFQRTGDS WAAADQMARGF++GATAGRTTLTGEGLQH DGHSLLLAATNP Sbjct 621 PVYVFYSMFGFQRTGDSIWAAADQMARGFLVGATAGRTTLTGEGLQHNDGHSLLLAATNP 680 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRG 718 AV AYDPAF+YE+A+IV+ GL RM GE+PEN+ +Y+TVYNEPYVQP EP + D + +LRG Sbjct 681 AVAAYDPAFSYEVAHIVKDGLRRMVGEDPENVIYYLTVYNEPYVQPAEPADLDVDALLRG 740 Query 719 IYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAI 778 +YRY A+ + ++LASGV++P ALRA MLA +W V A+VWSVTSWGEL RDGV Sbjct 741 LYRYAASPRPEGPQVRLLASGVSVPWALRARDMLAEQWGVGAEVWSVTSWGELRRDGVDA 800 Query 779 ETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGF 838 E L HP+ VPYV ALE + PV+AVSDWMRAVP+ +R WVP + TLGTDGFG Sbjct 801 ERHNLLHPEEAPKVPYVRTALEGSDAPVVAVSDWMRAVPDLVRQWVPAQFTTLGTDGFGL 860 Query 839 SDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 SDTRPAARR+F DAES VA L +LA GE+D +V AA +Y IDD AA QT+D G Sbjct 861 SDTRPAARRHFAVDAESITVAALGSLAARGEVDRAVVAEAAAKYAIDDPQAAGPQTSDSG 920 >gi|262203010|ref|YP_003274218.1| 2-oxo-acid dehydrogenase E1 subunit, homodimeric type [Gordonia bronchialis DSM 43247] gi|262086357|gb|ACY22325.1| 2-oxo-acid dehydrogenase E1 subunit, homodimeric type [Gordonia bronchialis DSM 43247] Length=943 Score = 1418 bits (3671), Expect = 0.0, Method: Compositional matrix adjust. Identities = 687/900 (77%), Positives = 760/900 (85%), Gaps = 2/900 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYLPDIDPEET EWLES D L+ + GPSRARYLMLRLLERAGE+RV+IP+LTSTDYVN Sbjct 42 VASYLPDIDPEETGEWLESLDQLIDQAGPSRARYLMLRLLERAGEKRVSIPSLTSTDYVN 101 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TI TE EPWFPGDE VERR+R +RWNAAIMVHRAQRPGVGVGGHISTYASSA LYEVGF Sbjct 102 TITTEREPWFPGDEAVERRFRRILRWNAAIMVHRAQRPGVGVGGHISTYASSATLYEVGF 161 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVG--GGLPSY 178 NHFFRG HPGGGDQ+FIQGHA+PGIYARAFLEGR+ ++DGFRQEHSH G GGLPSY Sbjct 162 NHFFRGLDHPGGGDQIFIQGHAAPGIYARAFLEGRIDESRMDGFRQEHSHAGEGGGLPSY 221 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMPDFW+FPTVSMGLGP+NAIYQARFNHYLHDRGIKDTSDQHVW FLGDGEMDE E Sbjct 222 PHPRLMPDFWQFPTVSMGLGPMNAIYQARFNHYLHDRGIKDTSDQHVWAFLGDGEMDEAE 281 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRG A A EGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKV+WGRE Sbjct 282 SRGFASFAATEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVIWGRE 341 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WD L +AD++GALVNLMNTTPDGD+QTY+ANDGG++RDHFF RDPRTK LV+NMSD DIW Sbjct 342 WDKLFYADKEGALVNLMNTTPDGDFQTYRANDGGFIRDHFFARDPRTKELVKNMSDADIW 401 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 +KRGGHDYRKVYAAY AA+ HKGQPTVILA TIKGY LG HFEGRNATHQMKKLTL+DL Sbjct 402 EMKRGGHDYRKVYAAYAAAMAHKGQPTVILAHTIKGYLLGSHFEGRNATHQMKKLTLDDL 461 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD RIP++DAQLEENPYLPPYY+PG + EI+YMLDRR+ALGG +P RRT SK L Sbjct 462 KAFRDNNRIPITDAQLEENPYLPPYYNPGPESAEIQYMLDRRKALGGSLPARRTSSKVLR 521 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 KGSG Q+VATTMA VR FK++LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 522 PDVSQALKTAAKGSGKQQVATTMALVRIFKDLLRDKEIGKRIVPIIPDEARTFGMDSWFP 581 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNRNGQLYTAVDA+LMLAYKES GQILHEGINEAGS SF A GTSY+TH+EPMI Sbjct 582 SLKIYNRNGQLYTAVDAELMLAYKESSEGQILHEGINEAGSAASFTAVGTSYSTHDEPMI 641 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGDSFWAAADQM RGF++GATAGRTTLTGEGLQHADG S LLAATNP Sbjct 642 PLYIFYSMFGFQRTGDSFWAAADQMTRGFLIGATAGRTTLTGEGLQHADGQSPLLAATNP 701 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRG 718 AVVAYDPAFA+E+ +I+ GL RM GENPEN+++Y+TVYNEP QP PEN D GVL+G Sbjct 702 AVVAYDPAFAFELGHIIADGLERMYGENPENVYYYLTVYNEPISQPARPENLDVAGVLKG 761 Query 719 IYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAI 778 IYR+ A E + + A IL SGV MP ALRA ++LA EW+V A+V+SVTSW EL RDG+ Sbjct 762 IYRFADAPEGKEHPASILVSGVTMPDALRAQELLAQEWNVGANVYSVTSWSELARDGIRA 821 Query 779 ETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGF 838 + +R P Y+T L + GP +AVSD+MR V EQIR +VPGTYLTLGTDGFGF Sbjct 822 DRAAVREPSADGARAYLTEVLADVPGPFVAVSDYMRGVQEQIRAYVPGTYLTLGTDGFGF 881 Query 839 SDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 SDTRPAARR+FN DAES VV VL ALA DG I +V AA +Y+I DV+AA D G Sbjct 882 SDTRPAARRFFNVDAESIVVGVLVALARDGHIPFTVAREAADKYQITDVSAAEVSYADTG 941 >gi|326382458|ref|ZP_08204149.1| pyruvate dehydrogenase subunit E1 [Gordonia neofelifaecis NRRL B-59395] gi|326198577|gb|EGD55760.1| pyruvate dehydrogenase subunit E1 [Gordonia neofelifaecis NRRL B-59395] Length=928 Score = 1416 bits (3665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 686/900 (77%), Positives = 766/900 (86%), Gaps = 3/900 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYL D DP ET EWLESFD +L GP RARYLMLR+LERA ++RV IPALT+TDYVN Sbjct 28 VASYLVDNDPTETDEWLESFDAMLADAGPERARYLMLRILERAEDKRVGIPALTNTDYVN 87 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEP FPGDED+ERRYRA IRWNAAIMVHRAQRPG+GVGGHISTYASSA+LYEVGF Sbjct 88 TIPTELEPEFPGDEDLERRYRAMIRWNAAIMVHRAQRPGIGVGGHISTYASSASLYEVGF 147 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVG--GGLPSY 178 N+FFRG+ HPGGGDQVFIQGHASPGIYARAFLEGR+ +LDGFRQE SH G GGLPSY Sbjct 148 NYFFRGQDHPGGGDQVFIQGHASPGIYARAFLEGRIDEARLDGFRQEQSHAGEGGGLPSY 207 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMP+FW+FPTVSMG+GP+NAIYQARFN YLH GIKDTSDQHVW FLGDGEMDEPE Sbjct 208 PHPRLMPEFWQFPTVSMGIGPMNAIYQARFNKYLHGNGIKDTSDQHVWAFLGDGEMDEPE 267 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGLA V A +GLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE Sbjct 268 SRGLAQVAATDGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 327 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WD+LLHAD DGALVNLMN T DGDYQTY+ANDG ++RDHFFGRD RTK LV ++SD+DIW Sbjct 328 WDSLLHADNDGALVNLMNKTTDGDYQTYRANDGAFIRDHFFGRDARTKELVNDLSDEDIW 387 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRK+YAAY AA+ HKGQPTVILAKTIKGY LGKHFEGRNATHQMKK+TL DL Sbjct 388 NLKRGGHDYRKIYAAYAAAMAHKGQPTVILAKTIKGYTLGKHFEGRNATHQMKKMTLADL 447 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRDT +P++DAQLE +PYLPPYYHPG+++PEI+YMLDRR LGGFVP R+ +K L Sbjct 448 KAFRDTAHVPITDAQLEADPYLPPYYHPGMDSPEIKYMLDRRSQLGGFVPSRKIAAKPLQ 507 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 + GSG+Q+VATTMA VR FKE+LRDK+IG RIVPIIPDEARTFGMDSWFP Sbjct 508 ADPAPALKAVSAGSGNQQVATTMALVRIFKELLRDKEIGKRIVPIIPDEARTFGMDSWFP 567 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 +LKIYN +GQ YT+VDA+LMLAYKE+E G+ILHEGINEAGS F A GTSYATH EPMI Sbjct 568 TLKIYNPHGQNYTSVDAELMLAYKEAENGRILHEGINEAGSTACFTAVGTSYATHGEPMI 627 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGD WAAADQM RGFV+GATAGRTTLTGEGLQHADGHS LLAATNP Sbjct 628 PLYIFYSMFGFQRTGDGLWAAADQMTRGFVIGATAGRTTLTGEGLQHADGHSPLLAATNP 687 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRG 718 V+YDPAFAYE+A+IV GL RM G + ENIF+Y+TVYNEP QP EP + D G+L+G Sbjct 688 GAVSYDPAFAYELAHIVVDGLERMYGPDAENIFYYVTVYNEPISQPAEPADLDVAGLLKG 747 Query 719 IYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAI 778 IYRY + Q +N A IL SGV M ALRA ++LA EWDVAADV+SVTSW EL RDG+A Sbjct 748 IYRYRRSEAQASNYANILVSGVTMGDALRAQELLAEEWDVAADVYSVTSWSELARDGIAA 807 Query 779 ETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGF 838 + +LR+P + PY+T L+ A+GP + VSD+MR V EQIR +VPGTYLTLG DGFGF Sbjct 808 DRAELRNPGS-STRPYLTEVLQYAKGPFVGVSDYMRGVQEQIRAYVPGTYLTLGADGFGF 866 Query 839 SDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 SDTRPAARRYFN DAES VV VL ALA DG+ID +V AAR+Y+IDDV AAPEQT+DPG Sbjct 867 SDTRPAARRYFNIDAESIVVGVLVALARDGKIDRTVAADAARKYQIDDVTAAPEQTSDPG 926 >gi|256375471|ref|YP_003099131.1| pyruvate dehydrogenase subunit E1 [Actinosynnema mirum DSM 43827] gi|255919774|gb|ACU35285.1| 2-oxo-acid dehydrogenase E1 subunit, homodimeric type [Actinosynnema mirum DSM 43827] Length=919 Score = 1409 bits (3646), Expect = 0.0, Method: Compositional matrix adjust. Identities = 677/900 (76%), Positives = 767/900 (86%), Gaps = 4/900 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +AS+LPDIDPEETSEWLESFD L+ G RARYLMLRLLERA E V +PALTSTDYVN Sbjct 20 LASHLPDIDPEETSEWLESFDAALKGGGQQRARYLMLRLLERARESHVGVPALTSTDYVN 79 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE+VERRYRAW+RWNAAI VHRAQRPGVGVGGHISTYASSA+LYEVGF Sbjct 80 TIPTEREPWFPGDEEVERRYRAWVRWNAAITVHRAQRPGVGVGGHISTYASSASLYEVGF 139 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSH--VGGGLPSY 178 NHFFRGK HPGGGDQVF+QGHASPG+YARAFLEGRLT +QLDGFRQE+SH +G GLPSY Sbjct 140 NHFFRGKDHPGGGDQVFVQGHASPGVYARAFLEGRLTTDQLDGFRQEYSHGGLGKGLPSY 199 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMP+FWEFPTVSMGLGP+NAIYQARFN YL RGIKDTS QHVW FLGDGEMDEPE Sbjct 200 PHPRLMPEFWEFPTVSMGLGPMNAIYQARFNRYLQSRGIKDTSQQHVWAFLGDGEMDEPE 259 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGL + A E LDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKV+WGRE Sbjct 260 SRGLLQLAANEQLDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVIWGRE 319 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WD+LLHADRDGALVNLMN TPDGD+QTYKANDG YV++HFFGRDPRTK LV MSD D+W Sbjct 320 WDSLLHADRDGALVNLMNQTPDGDFQTYKANDGAYVKEHFFGRDPRTKELVTAMSDDDVW 379 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRKV+AAY+AAV H GQPTVILAKTIKGY LG+ F RNATHQMKK++ +DL Sbjct 380 NLKRGGHDYRKVFAAYQAAVSHNGQPTVILAKTIKGYGLGERFAARNATHQMKKMSHDDL 439 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD+ RIP++D L +PYLPPYYHPG +APEI+Y+L+RR+ LGGFVPERR +K L Sbjct 440 KSFRDSLRIPIADKDL--DPYLPPYYHPGKDAPEIQYLLERRKQLGGFVPERRNTAKPLV 497 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 LPG +Y +K+GSG QEVATTMA VR +++++D +IG RIVPIIPDEARTFGMDS FP Sbjct 498 LPGDKVYDVVKRGSGKQEVATTMAFVRLVRDLIKDPEIGKRIVPIIPDEARTFGMDSMFP 557 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 S KIYN NGQLYT+VDA+LMLAYKESE GQILHEGINEAGS SF A GTSYATH EPMI Sbjct 558 SQKIYNPNGQLYTSVDAELMLAYKESEQGQILHEGINEAGSTASFTAVGTSYATHGEPMI 617 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 PIYIFYSMFGFQRTGD WAA DQMARGFVLGATAGRTTLTGEGLQHADGHSLLLA TNP Sbjct 618 PIYIFYSMFGFQRTGDGLWAAGDQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAHTNP 677 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRG 718 A VAYDPA+++E+A+IV+ GL RM GE+ EN+F+Y+T+YNEPY QP EPE+ D EG+L+G Sbjct 678 AAVAYDPAWSFEVAHIVKDGLRRMYGEDAENVFYYLTIYNEPYRQPAEPEDLDVEGLLKG 737 Query 719 IYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAI 778 +YRY + + KAQ+LASGV +P AL+AA++LA +W V ADVWS TS+ EL R+ V + Sbjct 738 LYRYQRSEGEGGPKAQLLASGVGVPWALKAARLLADDWGVHADVWSATSYSELRREAVEV 797 Query 779 ETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGF 838 + L +PD+ VPYVT+ L++A+GPV+AVSDWM AVP+ IRP+VP TLG DGFGF Sbjct 798 DRHNLLNPDKEPRVPYVTQVLKDAQGPVVAVSDWMTAVPDLIRPYVPTDMTTLGADGFGF 857 Query 839 SDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 SDTRPAARR+F DAES VVA L ALA GE+ V AAR+YRIDDV+AA T+D G Sbjct 858 SDTRPAARRHFLIDAESVVVATLAALAKRGEVPQQSVVDAARKYRIDDVSAAGPSTSDAG 917 >gi|302525298|ref|ZP_07277640.1| pyruvate dehydrogenase [Streptomyces sp. AA4] gi|302434193|gb|EFL06009.1| pyruvate dehydrogenase [Streptomyces sp. AA4] Length=931 Score = 1406 bits (3640), Expect = 0.0, Method: Compositional matrix adjust. Identities = 694/906 (77%), Positives = 771/906 (86%), Gaps = 8/906 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +A++LPDIDPEETSEWL+SFD L R G RARYLMLR+LERA E+ V +PALTSTDYVN Sbjct 24 LAAHLPDIDPEETSEWLDSFDEALARGGQQRARYLMLRILERARERNVGVPALTSTDYVN 83 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE++ERRYR +IRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 84 TIPTENEPWFPGDEEIERRYRRYIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 143 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVG--GGLPSY 178 NHFFRGK H GGGDQVF QGHASPG+YARAFLEGRLT +QLDGFRQE+SH G GGLPSY Sbjct 144 NHFFRGKDHSGGGDQVFFQGHASPGMYARAFLEGRLTEQQLDGFRQEYSHAGEGGGLPSY 203 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMP+FWE PTVSMGLGP+NAIYQARFN YLHDRGIKDTSDQHVW FLGDGEMDE E Sbjct 204 PHPRLMPEFWENPTVSMGLGPMNAIYQARFNRYLHDRGIKDTSDQHVWAFLGDGEMDEAE 263 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGL HV A EGLDNLTFVINCNLQRLDGPVRGNGKIIQELE++FRGAGWNVIKV+WGRE Sbjct 264 SRGLIHVAAGEGLDNLTFVINCNLQRLDGPVRGNGKIIQELEAYFRGAGWNVIKVIWGRE 323 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WD+LLHADRDGALVNLMN TPDGDYQTYKANDG +VR+HFFGRDPRTK LV++++DQ+IW Sbjct 324 WDSLLHADRDGALVNLMNVTPDGDYQTYKANDGAFVREHFFGRDPRTKDLVKDLTDQEIW 383 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRKVYAAY+AA++H GQPTVILA TIKGY LG FEGRNATHQMKKLTL+DL Sbjct 384 NLKRGGHDYRKVYAAYKAAMEHSGQPTVILAHTIKGYGLGPAFEGRNATHQMKKLTLDDL 443 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKS-KAL 477 K FRDTQRIP+SD +LE +P LPPYYHPG ++PEI YM RR+ALGG++PERR K+ KAL Sbjct 444 KLFRDTQRIPISDEELERDPKLPPYYHPGPDSPEIEYMRGRRKALGGYLPERRPKTAKAL 503 Query 478 TLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWF 537 LPG +Y ++KGSG QEVATTMA VR +E+ +D +IG RIVPIIPDEARTFG+DS F Sbjct 504 VLPGDKVYEGVRKGSGKQEVATTMAIVRLIRELAKDSEIGKRIVPIIPDEARTFGLDSMF 563 Query 538 PSLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPM 597 P+ KIYN +GQ YT+VDA LMLAYKESE GQ+LHEGINEAGS SF A GTSYATH EPM Sbjct 564 PTAKIYNPHGQTYTSVDASLMLAYKESEKGQLLHEGINEAGSTASFTAVGTSYATHGEPM 623 Query 598 IPIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATN 657 IPIYIFYSMFGFQRTGD +AAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATN Sbjct 624 IPIYIFYSMFGFQRTGDGLYAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATN 683 Query 658 PAVVAYDPAFAYEIAYIVESGLARMCGE-----NPENIFFYITVYNEPYVQPPEPENFDP 712 PAVVAYDPA+++EIA+IV+ GL RM GE N ENIF+YIT+YNEPY QP EPE+ D Sbjct 684 PAVVAYDPAYSFEIAHIVKDGLRRMYGETGPDGNGENIFYYITIYNEPYQQPAEPESLDV 743 Query 713 EGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELN 772 +GVL+G+YRY A E + Q+L SGV MP AL+A +MLA EW V A VWS TSWGEL Sbjct 744 DGVLKGLYRYSDAPEGDGPEVQVLVSGVTMPDALKAQKMLAEEWGVRAAVWSATSWGELR 803 Query 773 RDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLG 832 R+ V I+ E L HPD+ VPYVT+ L GPV+AVSDWMRAVP+ IRPWVP LTLG Sbjct 804 REAVEIDHENLLHPDQTPRVPYVTQKLSEVSGPVVAVSDWMRAVPDLIRPWVPTDMLTLG 863 Query 833 TDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPE 892 TDGFGFSDTRPAARR F DAES V L ALA GE D + AAR+YR+DDVAAA Sbjct 864 TDGFGFSDTRPAARRKFLVDAESITVGALSALAKRGEFDQAKVAEAARRYRLDDVAAAGP 923 Query 893 QTTDPG 898 QT+D G Sbjct 924 QTSDSG 929 >gi|300784030|ref|YP_003764321.1| pyruvate dehydrogenase E1 component [Amycolatopsis mediterranei U32] gi|299793544|gb|ADJ43919.1| pyruvate dehydrogenase E1 component [Amycolatopsis mediterranei U32] gi|340525433|gb|AEK40638.1| pyruvate dehydrogenase subunit E1 [Amycolatopsis mediterranei S699] Length=931 Score = 1402 bits (3629), Expect = 0.0, Method: Compositional matrix adjust. Identities = 679/906 (75%), Positives = 766/906 (85%), Gaps = 8/906 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +A++LPDIDPEET+EWL+SFD L R G RARYLMLR+LERA E+ V +PALTSTDYVN Sbjct 24 LAAHLPDIDPEETAEWLDSFDEALARGGQQRARYLMLRILERARERNVGVPALTSTDYVN 83 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTE EPWFPGDE++ERRYRA+IRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF Sbjct 84 TIPTENEPWFPGDEEIERRYRAYIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 143 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVG--GGLPSY 178 NHFFRGK H GGGDQ++IQGHASPGIYARAFLEGRL+ QLDGFRQE SH G GGLPSY Sbjct 144 NHFFRGKDHSGGGDQIYIQGHASPGIYARAFLEGRLSESQLDGFRQEFSHAGEGGGLPSY 203 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMP+FWE PTVSMGLGP+NAIYQARFN YL DRGIK+T DQH+W FLGDGEMDE E Sbjct 204 PHPRLMPEFWENPTVSMGLGPMNAIYQARFNRYLRDRGIKNTDDQHIWAFLGDGEMDEAE 263 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGL HV A EGLDNLTFVINCNLQRLDGPVRGNGKIIQELES+FRGAGWNVIKV+WGRE Sbjct 264 SRGLIHVAAGEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESYFRGAGWNVIKVIWGRE 323 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WD+LLHADRDGALVNLMN TPDGDYQTYKANDG +VR+HFFGRDPRTK LV+++SD DIW Sbjct 324 WDSLLHADRDGALVNLMNVTPDGDYQTYKANDGAFVREHFFGRDPRTKDLVKDLSDADIW 383 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRKVYAAY++A++H GQPTVILA TIKGY LG FEGRNATHQMKKLTL+DL Sbjct 384 NLKRGGHDYRKVYAAYKSALEHHGQPTVILAHTIKGYGLGPAFEGRNATHQMKKLTLDDL 443 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTK-SKAL 477 K FRD+QRIP+SD +LE NP LPPYYHPG N+PEI YM+ RR+ALGGF+PERR K +KAL Sbjct 444 KLFRDSQRIPISDEELERNPKLPPYYHPGANSPEIEYMIGRRKALGGFLPERRPKAAKAL 503 Query 478 TLPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWF 537 LPG +Y ++KGSG QEVATTMA VR +E+ +D +IG R+VPIIPDEARTFG+DS F Sbjct 504 VLPGDKVYEGIRKGSGKQEVATTMAFVRLVRELAKDSEIGKRVVPIIPDEARTFGLDSMF 563 Query 538 PSLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPM 597 P+ KIYN +GQ YT+VDA LMLAYKESE GQ+LHEGINEAGS SF A GTSYATH EPM Sbjct 564 PTAKIYNPHGQTYTSVDASLMLAYKESEKGQLLHEGINEAGSTASFTAVGTSYATHGEPM 623 Query 598 IPIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATN 657 IPIYIFYSMFGFQRTGD +AAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATN Sbjct 624 IPIYIFYSMFGFQRTGDGLYAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATN 683 Query 658 PAVVAYDPAFAYEIAYIVESGLARMCGE-----NPENIFFYITVYNEPYVQPPEPENFDP 712 PA VAYDPA+++EIA+IV+ GL RM GE N EN+F+Y+T+YNEPY QP EPEN D Sbjct 684 PAAVAYDPAWSFEIAHIVKDGLRRMYGEAGPDGNGENVFYYMTIYNEPYQQPAEPENLDV 743 Query 713 EGVLRGIYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELN 772 +G+L+G+Y+Y A + QIL SGV MP AL+A +MLA EW V A VWSVTSW EL Sbjct 744 DGLLKGLYKYADAPGGDGPEVQILVSGVTMPDALKAQKMLAEEWGVRAAVWSVTSWTELR 803 Query 773 RDGVAIETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLG 832 R+ V I+ + L +P VPYVT AL + GPV+AVSDWMRAVP+ IRP+VP LTLG Sbjct 804 REAVEIDHDNLLYPGSEPRVPYVTEALSGSNGPVVAVSDWMRAVPDLIRPYVPTDMLTLG 863 Query 833 TDGFGFSDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPE 892 TDGFGFSDTRPAARR F DAES V L LA GE++ + + AA +YR+DD+AAA Sbjct 864 TDGFGFSDTRPAARRKFLVDAESITVGALSILAKRGEVEQAKVLEAATKYRLDDIAAAGP 923 Query 893 QTTDPG 898 QT++ G Sbjct 924 QTSESG 929 >gi|317509071|ref|ZP_07966700.1| pyruvate dehydrogenase [Segniliparus rugosus ATCC BAA-974] gi|316252600|gb|EFV12041.1| pyruvate dehydrogenase [Segniliparus rugosus ATCC BAA-974] Length=911 Score = 1402 bits (3628), Expect = 0.0, Method: Compositional matrix adjust. Identities = 671/891 (76%), Positives = 758/891 (86%), Gaps = 2/891 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 VASYL D D +ET EWLES D+L+ R GP RAR+++LRLLERA E+ VA+P+LTSTD+VN Sbjct 15 VASYLADHDLQETEEWLESLDSLVAREGPERARFVILRLLERAHEKGVAVPSLTSTDFVN 74 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEP FPGDE++ERRYRAWIRWNAA+MVHRAQRPG+GVGGHISTYAS+A+LYEVGF Sbjct 75 TIPTELEPEFPGDEEIERRYRAWIRWNAAVMVHRAQRPGIGVGGHISTYASAASLYEVGF 134 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVG--GGLPSY 178 N F+RGKSHP GGDQVFIQGH SPGIYARAFLEGR+ + QLDGFRQE SH G GGLPSY Sbjct 135 NWFWRGKSHPSGGDQVFIQGHGSPGIYARAFLEGRIPSSQLDGFRQERSHEGRGGGLPSY 194 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRL+P FWEFPTVSMGLGP NAI QARFNHYLHDRGIKDTS QHVW FLGDGEMDEPE Sbjct 195 PHPRLLPGFWEFPTVSMGLGPANAIAQARFNHYLHDRGIKDTSGQHVWAFLGDGEMDEPE 254 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGL + A E LDNLTFV+NCNLQRLDGPVRGNGKIIQELESFFRGAGWNV+KV+WGRE Sbjct 255 SRGLLQIAATEALDNLTFVVNCNLQRLDGPVRGNGKIIQELESFFRGAGWNVVKVIWGRE 314 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHAD+DGALV +MN TPDGDYQTYKANDG YVR+HFFG+DPRTKALV + +D+ +W Sbjct 315 WDALLHADQDGALVKVMNETPDGDYQTYKANDGAYVREHFFGKDPRTKALVADYTDEQVW 374 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 NLKRGGHDYRK+YAAYR A+DH+GQPTVILA TIKGY LG +F GRNATHQMKKLTL+DL Sbjct 375 NLKRGGHDYRKIYAAYRRALDHQGQPTVILAHTIKGYGLGSNFAGRNATHQMKKLTLDDL 434 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD+ RIP+SDA LE +PYLPPYYHPG +APEI+Y+L+RRR LGGF+P+RRTK + L Sbjct 435 KNFRDSLRIPISDADLERDPYLPPYYHPGESAPEIQYLLERRRELGGFLPQRRTKPRPLA 494 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 LP YA LK GSG Q+VATTMA VR F+E+L+DK+IGPRIVPIIPDEARTFGMDSWFP Sbjct 495 LPDDKPYATLKTGSGKQQVATTMALVRLFRELLKDKEIGPRIVPIIPDEARTFGMDSWFP 554 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 SLKIYNR GQLYT+VDADLMLAYKES VGQILHEGINE GS SF A GTSYATH+E MI Sbjct 555 SLKIYNRLGQLYTSVDADLMLAYKESSVGQILHEGINECGSTSSFTAVGTSYATHDETMI 614 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 PIYIFYSMFGFQRT DS WAA+DQMA+GF+LGATAGRTTLTGEGLQHADGHSLL+A TNP Sbjct 615 PIYIFYSMFGFQRTADSIWAASDQMAKGFLLGATAGRTTLTGEGLQHADGHSLLIAHTNP 674 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRG 718 AVVAYDPAFAYEIA+IV+SGL+RM G +PE++ +YIT+YNEP QP EP + D +G+L+G Sbjct 675 AVVAYDPAFAYEIAHIVQSGLSRMFGPHPEDLIYYITLYNEPVHQPEEPADLDVDGLLKG 734 Query 719 IYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAI 778 +Y + +A ILASGV +P ALRA ++L W V A VWSVTSWG+L RDG Sbjct 735 MYLFRGPESDTGLQANILASGVILPEALRAQELLREHWQVGASVWSVTSWGQLARDGELS 794 Query 779 ETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGF 838 + LRHPD+P P+VT AL++A GPV+AVSDW RAVP IRPWVP + LG DGFGF Sbjct 795 DQSALRHPDQPRRAPHVTSALKSAVGPVVAVSDWARAVPNLIRPWVPHRFTALGADGFGF 854 Query 839 SDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAA 889 SDTR AARR FN DAES VVAVL +LA DG +D SV AA +Y IDDV A Sbjct 855 SDTRKAARRVFNIDAESIVVAVLLSLAEDGNLDRSVAAQAAERYHIDDVLA 905 >gi|291007423|ref|ZP_06565396.1| pyruvate dehydrogenase subunit E1 [Saccharopolyspora erythraea NRRL 2338] Length=946 Score = 1400 bits (3625), Expect = 0.0, Method: Compositional matrix adjust. Identities = 678/900 (76%), Positives = 771/900 (86%), Gaps = 2/900 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +AS+LPDIDPEET EWL+SFD++L G RARYLMLRLL+RA E V +P+LTSTDYVN Sbjct 45 LASHLPDIDPEETEEWLQSFDSVLSATGQQRARYLMLRLLQRARESGVGVPSLTSTDYVN 104 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDE+ ERRYRAW RWNAA+MVHRAQRPG+GVGGHIS+YASSA+LYEVGF Sbjct 105 TIPTELEPWFPGDEETERRYRAWTRWNAAMMVHRAQRPGIGVGGHISSYASSASLYEVGF 164 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVG--GGLPSY 178 N FF+GK HPGGGD ++IQGHASPGIYARAFLEGRL+ QLDGFRQE+SH G GGLPSY Sbjct 165 NWFFKGKDHPGGGDHLYIQGHASPGIYARAFLEGRLSTGQLDGFRQEYSHAGPGGGLPSY 224 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMPDFWEFPTVSMGLGP+NAI+QARF+ YL DRGIKDTS Q VW FLGDGEM+EPE Sbjct 225 PHPRLMPDFWEFPTVSMGLGPMNAIFQARFDRYLRDRGIKDTSQQRVWAFLGDGEMNEPE 284 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGL HV A EGLDNLTFV+NCNLQ+LDGPVRGNGKIIQELE+FFRGAGWNVIKV+WGRE Sbjct 285 SRGLLHVAANEGLDNLTFVVNCNLQQLDGPVRGNGKIIQELEAFFRGAGWNVIKVIWGRE 344 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGALVNLMNTTPDGDYQTYKANDG +VR+HFFGRDPRTK +V ++SD++IW Sbjct 345 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGAFVREHFFGRDPRTKDIVRDLSDEEIW 404 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 L+RGGHDYRKVYAAY+AA +H GQPTVILAKTIKGY LG HFEGRNATHQMKK+TL+DL Sbjct 405 GLRRGGHDYRKVYAAYKAATEHHGQPTVILAKTIKGYGLGPHFEGRNATHQMKKMTLDDL 464 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD+ RIP+SD QLE++PYLPPYYHPG + EI+Y+ +RR+ LGG++PERR KSKAL Sbjct 465 KLFRDSLRIPISDEQLEQDPYLPPYYHPGQESAEIQYLQERRQRLGGYLPERRVKSKALV 524 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 LPG +Y +++GSG QEVATTMA VR K++ +D +IGPRIVPIIPDEARTFGMDS FP Sbjct 525 LPGDKVYDVVRRGSGKQEVATTMAFVRLLKDLAKDPEIGPRIVPIIPDEARTFGMDSMFP 584 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 S KIYN GQ YT VD LMLAY+ESE GQILHEGINEAGS SF AAGTSYATH EPMI Sbjct 585 SQKIYNPLGQSYTPVDYQLMLAYRESEQGQILHEGINEAGSTASFTAAGTSYATHGEPMI 644 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGDS WAAADQM RGF+LGATAGRTTLTGEGLQHADGHSLLLAATNP Sbjct 645 PVYIFYSMFGFQRTGDSLWAAADQMTRGFLLGATAGRTTLTGEGLQHADGHSLLLAATNP 704 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRG 718 AVV+YDPA+A+E+A+IV+ GL RM GE+ EN+F+Y+TVYNEPY QP EPE D +G+LRG Sbjct 705 AVVSYDPAWAFEVAHIVKDGLRRMYGEDAENVFYYLTVYNEPYQQPAEPEGLDVDGLLRG 764 Query 719 IYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAI 778 +YRY A+ +AQILASGV MP ALRA ++LA +W V ADVWS TSW EL R+ A Sbjct 765 LYRYREASSGSGPRAQILASGVIMPEALRAQELLAEDWGVRADVWSATSWSELKREAEAA 824 Query 779 ETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGF 838 + L HP+ VP+VTRAL +A GPV+AVSDWMRAVP+ IRPWV G ++LGTDGFGF Sbjct 825 DRHNLLHPEGERRVPHVTRALADAGGPVVAVSDWMRAVPDMIRPWVRGDMVSLGTDGFGF 884 Query 839 SDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 SDTRPAARR F DAES VVA L ALA GE++ + AAR+Y+IDDV AA QT+DPG Sbjct 885 SDTRPAARRVFLVDAESTVVATLSALARQGEVEEAKVAEAARKYQIDDVKAAGPQTSDPG 944 >gi|134098118|ref|YP_001103779.1| pyruvate dehydrogenase subunit E1 [Saccharopolyspora erythraea NRRL 2338] gi|133910741|emb|CAM00854.1| pyruvate dehydrogenase E1 component [Saccharopolyspora erythraea NRRL 2338] Length=926 Score = 1400 bits (3623), Expect = 0.0, Method: Compositional matrix adjust. Identities = 678/900 (76%), Positives = 771/900 (86%), Gaps = 2/900 (0%) Query 1 VASYLPDIDPEETSEWLESFDTLLQRCGPSRARYLMLRLLERAGEQRVAIPALTSTDYVN 60 +AS+LPDIDPEET EWL+SFD++L G RARYLMLRLL+RA E V +P+LTSTDYVN Sbjct 25 LASHLPDIDPEETEEWLQSFDSVLSATGQQRARYLMLRLLQRARESGVGVPSLTSTDYVN 84 Query 61 TIPTELEPWFPGDEDVERRYRAWIRWNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGF 120 TIPTELEPWFPGDE+ ERRYRAW RWNAA+MVHRAQRPG+GVGGHIS+YASSA+LYEVGF Sbjct 85 TIPTELEPWFPGDEETERRYRAWTRWNAAMMVHRAQRPGIGVGGHISSYASSASLYEVGF 144 Query 121 NHFFRGKSHPGGGDQVFIQGHASPGIYARAFLEGRLTAEQLDGFRQEHSHVG--GGLPSY 178 N FF+GK HPGGGD ++IQGHASPGIYARAFLEGRL+ QLDGFRQE+SH G GGLPSY Sbjct 145 NWFFKGKDHPGGGDHLYIQGHASPGIYARAFLEGRLSTGQLDGFRQEYSHAGPGGGLPSY 204 Query 179 PHPRLMPDFWEFPTVSMGLGPLNAIYQARFNHYLHDRGIKDTSDQHVWCFLGDGEMDEPE 238 PHPRLMPDFWEFPTVSMGLGP+NAI+QARF+ YL DRGIKDTS Q VW FLGDGEM+EPE Sbjct 205 PHPRLMPDFWEFPTVSMGLGPMNAIFQARFDRYLRDRGIKDTSQQRVWAFLGDGEMNEPE 264 Query 239 SRGLAHVGALEGLDNLTFVINCNLQRLDGPVRGNGKIIQELESFFRGAGWNVIKVVWGRE 298 SRGL HV A EGLDNLTFV+NCNLQ+LDGPVRGNGKIIQELE+FFRGAGWNVIKV+WGRE Sbjct 265 SRGLLHVAANEGLDNLTFVVNCNLQQLDGPVRGNGKIIQELEAFFRGAGWNVIKVIWGRE 324 Query 299 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGGYVRDHFFGRDPRTKALVENMSDQDIW 358 WDALLHADRDGALVNLMNTTPDGDYQTYKANDG +VR+HFFGRDPRTK +V ++SD++IW Sbjct 325 WDALLHADRDGALVNLMNTTPDGDYQTYKANDGAFVREHFFGRDPRTKDIVRDLSDEEIW 384 Query 359 NLKRGGHDYRKVYAAYRAAVDHKGQPTVILAKTIKGYALGKHFEGRNATHQMKKLTLEDL 418 L+RGGHDYRKVYAAY+AA +H GQPTVILAKTIKGY LG HFEGRNATHQMKK+TL+DL Sbjct 385 GLRRGGHDYRKVYAAYKAATEHHGQPTVILAKTIKGYGLGPHFEGRNATHQMKKMTLDDL 444 Query 419 KEFRDTQRIPVSDAQLEENPYLPPYYHPGLNAPEIRYMLDRRRALGGFVPERRTKSKALT 478 K FRD+ RIP+SD QLE++PYLPPYYHPG + EI+Y+ +RR+ LGG++PERR KSKAL Sbjct 445 KLFRDSLRIPISDEQLEQDPYLPPYYHPGQESAEIQYLQERRQRLGGYLPERRVKSKALV 504 Query 479 LPGRDIYAPLKKGSGHQEVATTMATVRTFKEVLRDKQIGPRIVPIIPDEARTFGMDSWFP 538 LPG +Y +++GSG QEVATTMA VR K++ +D +IGPRIVPIIPDEARTFGMDS FP Sbjct 505 LPGDKVYDVVRRGSGKQEVATTMAFVRLLKDLAKDPEIGPRIVPIIPDEARTFGMDSMFP 564 Query 539 SLKIYNRNGQLYTAVDADLMLAYKESEVGQILHEGINEAGSVGSFIAAGTSYATHNEPMI 598 S KIYN GQ YT VD LMLAY+ESE GQILHEGINEAGS SF AAGTSYATH EPMI Sbjct 565 SQKIYNPLGQSYTPVDYQLMLAYRESEQGQILHEGINEAGSTASFTAAGTSYATHGEPMI 624 Query 599 PIYIFYSMFGFQRTGDSFWAAADQMARGFVLGATAGRTTLTGEGLQHADGHSLLLAATNP 658 P+YIFYSMFGFQRTGDS WAAADQM RGF+LGATAGRTTLTGEGLQHADGHSLLLAATNP Sbjct 625 PVYIFYSMFGFQRTGDSLWAAADQMTRGFLLGATAGRTTLTGEGLQHADGHSLLLAATNP 684 Query 659 AVVAYDPAFAYEIAYIVESGLARMCGENPENIFFYITVYNEPYVQPPEPENFDPEGVLRG 718 AVV+YDPA+A+E+A+IV+ GL RM GE+ EN+F+Y+TVYNEPY QP EPE D +G+LRG Sbjct 685 AVVSYDPAWAFEVAHIVKDGLRRMYGEDAENVFYYLTVYNEPYQQPAEPEGLDVDGLLRG 744 Query 719 IYRYHAATEQRTNKAQILASGVAMPAALRAAQMLAAEWDVAADVWSVTSWGELNRDGVAI 778 +YRY A+ +AQILASGV MP ALRA ++LA +W V ADVWS TSW EL R+ A Sbjct 745 LYRYREASSGSGPRAQILASGVIMPEALRAQELLAEDWGVRADVWSATSWSELKREAEAA 804 Query 779 ETEKLRHPDRPAGVPYVTRALENARGPVIAVSDWMRAVPEQIRPWVPGTYLTLGTDGFGF 838 + L HP+ VP+VTRAL +A GPV+AVSDWMRAVP+ IRPWV G ++LGTDGFGF Sbjct 805 DRHNLLHPEGERRVPHVTRALADAGGPVVAVSDWMRAVPDMIRPWVRGDMVSLGTDGFGF 864 Query 839 SDTRPAARRYFNTDAESQVVAVLEALAGDGEIDPSVPVAAARQYRIDDVAAAPEQTTDPG 898 SDTRPAARR F DAES VVA L ALA GE++ + AAR+Y+IDDV AA QT+DPG Sbjct 865 SDTRPAARRVFLVDAESTVVATLSALARQGEVEEAKVAEAARKYQIDDVKAAGPQTSDPG 924 Lambda K H 0.319 0.137 0.424 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 2218897076512 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40