BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv2250c
Length=189
Score E
Sequences producing significant alignments: (Bits) Value
gi|57116959|ref|NP_216766.2| transcriptional regulator [Mycobact... 369 1e-100
gi|15841743|ref|NP_336780.1| TetR family transcriptional regulat... 368 2e-100
gi|148823458|ref|YP_001288212.1| transcriptional regulator [Myco... 367 5e-100
gi|31793430|ref|NP_855923.1| transcriptional regulator [Mycobact... 366 8e-100
gi|308369671|ref|ZP_07666780.1| transcriptional regulator [Mycob... 364 4e-99
gi|308232079|ref|ZP_07663996.1| transcriptional regulator [Mycob... 360 4e-98
gi|339295166|gb|AEJ47277.1| TetR family transcriptional regulato... 314 4e-84
gi|183983333|ref|YP_001851624.1| transcriptional regulatory prot... 283 8e-75
gi|118616998|ref|YP_905330.1| transcriptional regulatory protein... 283 1e-74
gi|240170087|ref|ZP_04748746.1| transcriptional regulatory prote... 281 4e-74
gi|118464377|ref|YP_881396.1| TetR family transcriptional regula... 276 1e-72
gi|254774897|ref|ZP_05216413.1| transcriptional regulator, TetR ... 274 4e-72
gi|336461777|gb|EGO40635.1| transcriptional regulator [Mycobacte... 274 6e-72
gi|41408101|ref|NP_960937.1| hypothetical protein MAP2003c [Myco... 273 9e-72
gi|296166143|ref|ZP_06848588.1| TetR family transcriptional regu... 269 1e-70
gi|342857278|ref|ZP_08713934.1| TetR family transcriptional regu... 249 1e-64
gi|254823483|ref|ZP_05228484.1| transcriptional regulator, TetR ... 248 3e-64
gi|118468535|ref|YP_888608.1| TetR family transcriptional regula... 233 1e-59
gi|108800339|ref|YP_640536.1| TetR family transcriptional regula... 207 5e-52
gi|333990283|ref|YP_004522897.1| transcriptional regulator [Myco... 205 3e-51
gi|145223360|ref|YP_001134038.1| TetR family transcriptional reg... 201 3e-50
gi|120404719|ref|YP_954548.1| TetR family transcriptional regula... 197 7e-49
gi|315443819|ref|YP_004076698.1| TetR family transcriptional reg... 197 9e-49
gi|111023719|ref|YP_706691.1| TetR family transcriptional regula... 159 2e-37
gi|325672743|ref|ZP_08152439.1| TetR family transcriptional regu... 157 5e-37
gi|312139376|ref|YP_004006712.1| tetr family transcriptional reg... 156 1e-36
gi|226366156|ref|YP_002783939.1| TetR family transcriptional reg... 155 2e-36
gi|226306236|ref|YP_002766196.1| TetR family transcriptional reg... 147 7e-34
gi|229490880|ref|ZP_04384715.1| regulatory protein, TetR [Rhodoc... 144 5e-33
gi|169630962|ref|YP_001704611.1| TetR family transcriptional reg... 143 1e-32
gi|54023311|ref|YP_117553.1| putative transcriptional regulator ... 143 1e-32
gi|343928708|ref|ZP_08768153.1| putative TetR family transcripti... 128 4e-28
gi|317509229|ref|ZP_07966850.1| tetR family bacterial regulatory... 122 2e-26
gi|297559284|ref|YP_003678258.1| TetR family transcriptional reg... 119 3e-25
gi|111221025|ref|YP_711819.1| TetR family transcriptional regula... 118 4e-25
gi|158317350|ref|YP_001509858.1| TetR family transcriptional reg... 109 2e-22
gi|145595106|ref|YP_001159403.1| regulatory protein TetR [Salini... 107 8e-22
gi|331698318|ref|YP_004334557.1| regulatory protein TetR [Pseudo... 106 2e-21
gi|86739655|ref|YP_480055.1| TetR family transcriptional regulat... 101 5e-20
gi|159038349|ref|YP_001537602.1| TetR family transcriptional reg... 100 9e-20
gi|262204636|ref|YP_003275844.1| TetR family transcriptional reg... 100 1e-19
gi|300790225|ref|YP_003770516.1| TetR family transcriptional reg... 99.4 2e-19
gi|269126039|ref|YP_003299409.1| TetR family transcriptional reg... 96.7 1e-18
gi|308372188|ref|ZP_07667325.1| LOW QUALITY PROTEIN: putative tr... 95.9 3e-18
gi|134097268|ref|YP_001102929.1| TetR family transcriptional reg... 95.1 4e-18
gi|302530478|ref|ZP_07282820.1| TetR-family transcriptional regu... 94.7 5e-18
gi|288923564|ref|ZP_06417677.1| transcriptional regulator, TetR ... 94.7 6e-18
gi|257057287|ref|YP_003135119.1| transcriptional regulator [Sacc... 91.3 6e-17
gi|21219199|ref|NP_624978.1| TetR family transcriptional regulat... 90.9 9e-17
gi|291441483|ref|ZP_06580873.1| TetR-family transcriptional regu... 89.4 3e-16
>gi|57116959|ref|NP_216766.2| transcriptional regulator [Mycobacterium tuberculosis H37Rv]
gi|121638133|ref|YP_978357.1| putative transcriptional regulatory protein [Mycobacterium bovis
BCG str. Pasteur 1173P2]
gi|148662071|ref|YP_001283594.1| putative transcriptional regulatory protein [Mycobacterium tuberculosis
H37Ra]
48 more sequence titles
Length=189
Score = 369 bits (947), Expect = 1e-100, Method: Compositional matrix adjust.
Identities = 189/189 (100%), Positives = 189/189 (100%), Gaps = 0/189 (0%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS
Sbjct 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS
Sbjct 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
Query 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL
Sbjct 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
Query 181 THALNGYLC 189
THALNGYLC
Sbjct 181 THALNGYLC 189
>gi|15841743|ref|NP_336780.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CDC1551]
gi|254232399|ref|ZP_04925726.1| hypothetical protein TBCG_02198 [Mycobacterium tuberculosis C]
gi|289745525|ref|ZP_06504903.1| transcriptional regulator [Mycobacterium tuberculosis 02_1987]
gi|289745526|ref|ZP_06504904.1| transcriptional regulator [Mycobacterium tuberculosis 02_1987]
gi|13882002|gb|AAK46594.1| transcriptional regulator, TetR family [Mycobacterium tuberculosis
CDC1551]
gi|124601458|gb|EAY60468.1| hypothetical protein TBCG_02198 [Mycobacterium tuberculosis C]
gi|289686053|gb|EFD53541.1| transcriptional regulator [Mycobacterium tuberculosis 02_1987]
gi|289686054|gb|EFD53542.1| transcriptional regulator [Mycobacterium tuberculosis 02_1987]
Length=219
Score = 368 bits (945), Expect = 2e-100, Method: Compositional matrix adjust.
Identities = 189/189 (100%), Positives = 189/189 (100%), Gaps = 0/189 (0%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS
Sbjct 31 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 90
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS
Sbjct 91 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 150
Query 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL
Sbjct 151 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 210
Query 181 THALNGYLC 189
THALNGYLC
Sbjct 211 THALNGYLC 219
>gi|148823458|ref|YP_001288212.1| transcriptional regulator [Mycobacterium tuberculosis F11]
gi|148721985|gb|ABR06610.1| hypothetical transcriptional regulatory protein [Mycobacterium
tuberculosis F11]
Length=189
Score = 367 bits (942), Expect = 5e-100, Method: Compositional matrix adjust.
Identities = 188/189 (99%), Positives = 188/189 (99%), Gaps = 0/189 (0%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS
Sbjct 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLG S
Sbjct 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGAS 120
Query 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL
Sbjct 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
Query 181 THALNGYLC 189
THALNGYLC
Sbjct 181 THALNGYLC 189
>gi|31793430|ref|NP_855923.1| transcriptional regulator [Mycobacterium bovis AF2122/97]
gi|56404859|sp|Q7VEN0.1|Y2274_MYCBO RecName: Full=Uncharacterized HTH-type transcriptional regulator
Mb2274c
gi|31619022|emb|CAD97127.1| Possible transcriptional regulatory protein [Mycobacterium bovis
AF2122/97]
Length=189
Score = 366 bits (940), Expect = 8e-100, Method: Compositional matrix adjust.
Identities = 188/189 (99%), Positives = 188/189 (99%), Gaps = 0/189 (0%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS
Sbjct 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
MLTSHIA VLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS
Sbjct 61 MLTSHIAAVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
Query 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL
Sbjct 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
Query 181 THALNGYLC 189
THALNGYLC
Sbjct 181 THALNGYLC 189
>gi|308369671|ref|ZP_07666780.1| transcriptional regulator [Mycobacterium tuberculosis SUMu002]
gi|308370960|ref|ZP_07667059.1| transcriptional regulator [Mycobacterium tuberculosis SUMu003]
gi|308373364|ref|ZP_07667562.1| transcriptional regulator [Mycobacterium tuberculosis SUMu005]
10 more sequence titles
Length=186
Score = 364 bits (934), Expect = 4e-99, Method: Compositional matrix adjust.
Identities = 186/186 (100%), Positives = 186/186 (100%), Gaps = 0/186 (0%)
Query 4 MSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLT 63
MSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLT
Sbjct 1 MSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLT 60
Query 64 SHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQV 123
SHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQV
Sbjct 61 SHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQV 120
Query 124 LIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHA 183
LIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHA
Sbjct 121 LIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHA 180
Query 184 LNGYLC 189
LNGYLC
Sbjct 181 LNGYLC 186
>gi|308232079|ref|ZP_07663996.1| transcriptional regulator [Mycobacterium tuberculosis SUMu001]
gi|308379159|ref|ZP_07668908.1| transcriptional regulator [Mycobacterium tuberculosis SUMu010]
gi|308380312|ref|ZP_07669162.1| transcriptional regulator [Mycobacterium tuberculosis SUMu011]
gi|308215143|gb|EFO74542.1| transcriptional regulator [Mycobacterium tuberculosis SUMu001]
gi|308358019|gb|EFP46870.1| transcriptional regulator [Mycobacterium tuberculosis SUMu010]
gi|308361955|gb|EFP50806.1| transcriptional regulator [Mycobacterium tuberculosis SUMu011]
Length=186
Score = 360 bits (925), Expect = 4e-98, Method: Compositional matrix adjust.
Identities = 185/186 (99%), Positives = 185/186 (99%), Gaps = 0/186 (0%)
Query 4 MSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLT 63
MSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLT
Sbjct 1 MSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLT 60
Query 64 SHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQV 123
SHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQV
Sbjct 61 SHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTSQQV 120
Query 124 LIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHA 183
LIEGLAARLT AQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHA
Sbjct 121 LIEGLAARLTGAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHA 180
Query 184 LNGYLC 189
LNGYLC
Sbjct 181 LNGYLC 186
>gi|339295166|gb|AEJ47277.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CCDC5079]
gi|339298786|gb|AEJ50896.1| TetR family transcriptional regulator [Mycobacterium tuberculosis
CCDC5180]
Length=162
Score = 314 bits (805), Expect = 4e-84, Method: Compositional matrix adjust.
Identities = 161/162 (99%), Positives = 162/162 (100%), Gaps = 0/162 (0%)
Query 28 VDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVPLDGDDREALVKQI 87
+DRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVPLDGDDREALVKQI
Sbjct 1 MDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVPLDGDDREALVKQI 60
Query 88 VAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAARLTVAQRSGSVRSGDAR 147
VAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAARLTVAQRSGSVRSGDAR
Sbjct 61 VAVADRLRGDDLIMSVMHSELARVYITERLGTSQQVLIEGLAARLTVAQRSGSVRSGDAR 120
Query 148 RLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC 189
RLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC
Sbjct 121 RLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC 162
>gi|183983333|ref|YP_001851624.1| transcriptional regulatory protein [Mycobacterium marinum M]
gi|183176659|gb|ACC41769.1| transcriptional regulatory protein [Mycobacterium marinum M]
Length=189
Score = 283 bits (724), Expect = 8e-75, Method: Compositional matrix adjust.
Identities = 141/189 (75%), Positives = 164/189 (87%), Gaps = 0/189 (0%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
MLSMSN D G RIL+AAASCV DYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSI+++
Sbjct 1 MLSMSNAPEDIGDRILQAAASCVRDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIISA 60
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
+LTSH+ DV+R V LDG DR+ +V+Q+VAVADRLRGD+L+ ++MHS+LARVYITERLG S
Sbjct 61 LLTSHVTDVVRAVSLDGHDRQTVVRQVVAVADRLRGDELVKALMHSDLARVYITERLGAS 120
Query 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
Q L+EGLAARL VAQ +GSVR+GD R+LA MVLLI QSTIQS DI+D ILDS ALA EL
Sbjct 121 QHFLLEGLAARLQVAQGTGSVRAGDPRKLAAMVLLITQSTIQSVDIIDPILDSEALAAEL 180
Query 181 THALNGYLC 189
T++LNGYL
Sbjct 181 TYSLNGYLA 189
>gi|118616998|ref|YP_905330.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
gi|118569108|gb|ABL03859.1| transcriptional regulatory protein [Mycobacterium ulcerans Agy99]
Length=189
Score = 283 bits (723), Expect = 1e-74, Method: Compositional matrix adjust.
Identities = 141/189 (75%), Positives = 164/189 (87%), Gaps = 0/189 (0%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
MLSMSN D G RIL+AAASCV DYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSI+++
Sbjct 1 MLSMSNAPEDIGDRILQAAASCVRDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIISA 60
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
+LTSH+ DV+R V LDG DR+ +V+Q+VAVADRLRGD+L+ ++MHS+LARVYITERLG S
Sbjct 61 LLTSHVTDVVRAVFLDGHDRQTVVRQVVAVADRLRGDELVKALMHSDLARVYITERLGAS 120
Query 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
Q L+EGLAARL VAQ +GSVR+GD R+LA MVLLI QSTIQS DI+D ILDS ALA EL
Sbjct 121 QHFLLEGLAARLQVAQGTGSVRAGDPRKLAAMVLLITQSTIQSVDIIDPILDSEALAAEL 180
Query 181 THALNGYLC 189
T++LNGYL
Sbjct 181 TYSLNGYLA 189
>gi|240170087|ref|ZP_04748746.1| transcriptional regulatory protein [Mycobacterium kansasii ATCC
12478]
Length=189
Score = 281 bits (718), Expect = 4e-74, Method: Compositional matrix adjust.
Identities = 151/189 (80%), Positives = 168/189 (89%), Gaps = 0/189 (0%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
MLS SN + G RIL AAASCV DYGVD+V LAEIARRAGVSRPTVYRRWPDTRSI+A+
Sbjct 1 MLSTSNAPENIGARILAAAASCVRDYGVDKVALAEIARRAGVSRPTVYRRWPDTRSIIAA 60
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
+LTSHI DVL E+PLDGDDREA+V+Q+VAVADRLR DDLI ++MHS+LARVYITERLGTS
Sbjct 61 LLTSHITDVLDELPLDGDDREAVVRQVVAVADRLRRDDLIKALMHSDLARVYITERLGTS 120
Query 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
QQ LIEGLAARL VAQRSGSVR+GD R+LATMVLLIAQSTIQS DIV+ ILDS ALA EL
Sbjct 121 QQFLIEGLAARLKVAQRSGSVRAGDPRQLATMVLLIAQSTIQSVDIVNPILDSQALAAEL 180
Query 181 THALNGYLC 189
T++LNGYL
Sbjct 181 TYSLNGYLA 189
>gi|118464377|ref|YP_881396.1| TetR family transcriptional regulator [Mycobacterium avium 104]
gi|118165664|gb|ABK66561.1| transcriptional regulator, TetR family protein [Mycobacterium
avium 104]
Length=193
Score = 276 bits (706), Expect = 1e-72, Method: Compositional matrix adjust.
Identities = 142/192 (74%), Positives = 164/192 (86%), Gaps = 4/192 (2%)
Query 1 MLSMSNDRAD----TGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRS 56
MLS+ NDR D TG RIL AAASCVVD+GVDRVTLAEIARRAGVSRPTVYRRWPDTRS
Sbjct 1 MLSIRNDRPDAALDTGERILAAAASCVVDFGVDRVTLAEIARRAGVSRPTVYRRWPDTRS 60
Query 57 IMASMLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITER 116
I+A++LT H+ DV+R PL GDDRE+LV+QIV VAD LR D L+MSV+HSELA +YITER
Sbjct 61 IVAALLTRHVTDVMRAAPLLGDDRESLVRQIVTVADLLRQDRLVMSVLHSELAPIYITER 120
Query 117 LGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAAL 176
LGTSQ +LI+ LAARL VAQR+GSVR GD ++ATMVLLIAQSTIQSA IV+ +LD+ AL
Sbjct 121 LGTSQHMLIDALAARLRVAQRNGSVRPGDPVQMATMVLLIAQSTIQSAQIVEPLLDAEAL 180
Query 177 ATELTHALNGYL 188
ATEL ++LNGYL
Sbjct 181 ATELAYSLNGYL 192
>gi|254774897|ref|ZP_05216413.1| transcriptional regulator, TetR family protein [Mycobacterium
avium subsp. avium ATCC 25291]
Length=193
Score = 274 bits (701), Expect = 4e-72, Method: Compositional matrix adjust.
Identities = 141/192 (74%), Positives = 163/192 (85%), Gaps = 4/192 (2%)
Query 1 MLSMSNDRAD----TGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRS 56
MLS+ NDR D TG RIL AAASCVVD+GVDRVTLAEIARRAGVSRPTVYRRWPDTRS
Sbjct 1 MLSIRNDRPDAALDTGERILAAAASCVVDFGVDRVTLAEIARRAGVSRPTVYRRWPDTRS 60
Query 57 IMASMLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITER 116
I+A++LT H+ DV+R PL GDDRE+LV+QIV AD LR D L+MSV+HSELA +YITER
Sbjct 61 IVAALLTRHVTDVMRAAPLLGDDRESLVRQIVTAADLLRQDRLVMSVLHSELAPIYITER 120
Query 117 LGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAAL 176
LGTSQ +LI+ LAARL VAQR+GSVR GD ++ATMVLLIAQSTIQSA IV+ +LD+ AL
Sbjct 121 LGTSQHMLIDALAARLRVAQRNGSVRPGDPVQMATMVLLIAQSTIQSAQIVEPLLDAEAL 180
Query 177 ATELTHALNGYL 188
ATEL ++LNGYL
Sbjct 181 ATELAYSLNGYL 192
>gi|336461777|gb|EGO40635.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis
S397]
Length=193
Score = 274 bits (700), Expect = 6e-72, Method: Compositional matrix adjust.
Identities = 140/192 (73%), Positives = 163/192 (85%), Gaps = 4/192 (2%)
Query 1 MLSMSNDRAD----TGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRS 56
MLS+ ND+ D TG RIL AAASCVVD+GVDRVTLAEIARRAGVSRPTVYRRWPDTRS
Sbjct 1 MLSIRNDKPDAVLDTGERILAAAASCVVDFGVDRVTLAEIARRAGVSRPTVYRRWPDTRS 60
Query 57 IMASMLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITER 116
I+A++LT H+ DV+R PL GDDRE+LV+QIV VAD LR D L+MSV+HSELA +YITER
Sbjct 61 IVAALLTRHVTDVMRAAPLLGDDRESLVRQIVTVADLLRQDRLVMSVLHSELAPIYITER 120
Query 117 LGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAAL 176
LGTSQ +LI+ LAARL VAQR+GSVR GD ++ATMVLLIAQSTIQSA IV+ +LD+ AL
Sbjct 121 LGTSQHMLIDALAARLRVAQRNGSVRPGDPVQMATMVLLIAQSTIQSAQIVEPLLDAEAL 180
Query 177 ATELTHALNGYL 188
A EL ++LNGYL
Sbjct 181 AKELAYSLNGYL 192
>gi|41408101|ref|NP_960937.1| hypothetical protein MAP2003c [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|41396456|gb|AAS04320.1| hypothetical protein MAP_2003c [Mycobacterium avium subsp. paratuberculosis
K-10]
Length=230
Score = 273 bits (698), Expect = 9e-72, Method: Compositional matrix adjust.
Identities = 140/192 (73%), Positives = 163/192 (85%), Gaps = 4/192 (2%)
Query 1 MLSMSNDRAD----TGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRS 56
MLS+ ND+ D TG RIL AAASCVVD+GVDRVTLAEIARRAGVSRPTVYRRWPDTRS
Sbjct 38 MLSIRNDKPDAVLDTGERILAAAASCVVDFGVDRVTLAEIARRAGVSRPTVYRRWPDTRS 97
Query 57 IMASMLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITER 116
I+A++LT H+ DV+R PL GDDRE+LV+QIV VAD LR D L+MSV+HSELA +YITER
Sbjct 98 IVAALLTRHVTDVMRAAPLLGDDRESLVRQIVTVADLLRQDRLVMSVLHSELAPIYITER 157
Query 117 LGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAAL 176
LGTSQ +LI+ LAARL VAQR+GSVR GD ++ATMVLLIAQSTIQSA IV+ +LD+ AL
Sbjct 158 LGTSQHMLIDALAARLRVAQRNGSVRPGDPVQMATMVLLIAQSTIQSAQIVEPLLDAEAL 217
Query 177 ATELTHALNGYL 188
A EL ++LNGYL
Sbjct 218 AKELAYSLNGYL 229
>gi|296166143|ref|ZP_06848588.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
gi|295898552|gb|EFG78113.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum
ATCC BAA-614]
Length=191
Score = 269 bits (688), Expect = 1e-70, Method: Compositional matrix adjust.
Identities = 139/190 (74%), Positives = 164/190 (87%), Gaps = 2/190 (1%)
Query 1 MLSMSNDRA--DTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIM 58
MLS+SNDRA DTG RIL AAASCVVD+GVDRVTLAEIARRAGVSRPTVYRR+PDTRSI+
Sbjct 1 MLSISNDRARVDTGERILAAAASCVVDFGVDRVTLAEIARRAGVSRPTVYRRFPDTRSIV 60
Query 59 ASMLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLG 118
A++LT H+ +V+R PL GDDRE+LV+QIV VA+ LR D L+MSV+HSELA +YITERLG
Sbjct 61 AALLTRHVTEVMRAAPLLGDDRESLVRQIVTVANLLRRDRLVMSVLHSELAPIYITERLG 120
Query 119 TSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALAT 178
TSQ +LI+ LAARL AQR+GSVR+GD ++ATMVLLIAQSTIQSA IV+ ILD+ LA
Sbjct 121 TSQHMLIDALAARLREAQRNGSVRAGDPVQMATMVLLIAQSTIQSAQIVEPILDADTLAA 180
Query 179 ELTHALNGYL 188
EL ++LNGYL
Sbjct 181 ELAYSLNGYL 190
>gi|342857278|ref|ZP_08713934.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
gi|342134611|gb|EGT87777.1| TetR family transcriptional regulator [Mycobacterium colombiense
CECT 3035]
Length=189
Score = 249 bits (636), Expect = 1e-64, Method: Compositional matrix adjust.
Identities = 132/188 (71%), Positives = 160/188 (86%), Gaps = 0/188 (0%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
MLS+ N++ DTG RIL AAASCVVD+GV+RVTLAEIARRAGVSRPTVYRRWPDT SI+A+
Sbjct 1 MLSIRNEKLDTGERILAAAASCVVDFGVERVTLAEIARRAGVSRPTVYRRWPDTPSIVAA 60
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
+LT HI +V+++ PL G+DRE+LV+QIV V D LR D L+ SV+HS+LA YITERLGTS
Sbjct 61 LLTQHITEVMQDAPLLGNDRESLVRQIVTVTDLLRADRLVTSVLHSDLASTYITERLGTS 120
Query 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
Q++LI+ LAARL AQR GSVR GD ++ATMVLLIAQSTIQSA IV+ +LD+ ALATEL
Sbjct 121 QRMLIDALAARLRAAQRHGSVRLGDPVQMATMVLLIAQSTIQSARIVEPMLDADALATEL 180
Query 181 THALNGYL 188
++LNGYL
Sbjct 181 AYSLNGYL 188
>gi|254823483|ref|ZP_05228484.1| transcriptional regulator, TetR family protein [Mycobacterium
intracellulare ATCC 13950]
Length=188
Score = 248 bits (634), Expect = 3e-64, Method: Compositional matrix adjust.
Identities = 136/188 (73%), Positives = 159/188 (85%), Gaps = 1/188 (0%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
MLS+ N+ D G RIL AAASCVVD+GVDRVTLAEIARRAGVSRPTVYRRWPDT S++A+
Sbjct 1 MLSIRNE-LDVGERILAAAASCVVDFGVDRVTLAEIARRAGVSRPTVYRRWPDTHSVVAA 59
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSELARVYITERLGTS 120
+LT H+ +V+ + PL GDDRE+LV+QIV VAD LR D L+MSV+HSELA YITERLGTS
Sbjct 60 LLTRHVTEVMSDAPLLGDDRESLVRQIVTVADLLRQDPLVMSVLHSELATTYITERLGTS 119
Query 121 QQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATEL 180
Q++LI+ LAARL VAQR GSVRSGD ++ATMVLLIAQSTIQSA IV +LD+ ALA EL
Sbjct 120 QRMLIDALAARLRVAQRHGSVRSGDPVQMATMVLLIAQSTIQSARIVAPMLDADALAAEL 179
Query 181 THALNGYL 188
H+LNGYL
Sbjct 180 AHSLNGYL 187
>gi|118468535|ref|YP_888608.1| TetR family transcriptional regulator [Mycobacterium smegmatis
str. MC2 155]
gi|118169822|gb|ABK70718.1| transcriptional regulator, TetR family protein [Mycobacterium
smegmatis str. MC2 155]
Length=194
Score = 233 bits (593), Expect = 1e-59, Method: Compositional matrix adjust.
Identities = 125/192 (66%), Positives = 155/192 (81%), Gaps = 4/192 (2%)
Query 1 MLSMSNDRA--DTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIM 58
M+S+SND A G RIL AAASCV+ +GVDRVTLAEIARRAGVSRPTVYRR+PDTRSI+
Sbjct 1 MVSISNDDAGESLGERILEAAASCVMAFGVDRVTLAEIARRAGVSRPTVYRRFPDTRSIL 60
Query 59 ASMLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITER 116
A++LT+ I VL EV D REALV++IVAVA+RLR D++IM+V+H+ ++A VYI ER
Sbjct 61 AALLTARIVRVLDEVESDARGREALVRRIVAVAERLRHDEVIMAVLHTAPDVAMVYIAER 120
Query 117 LGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAAL 176
LGTSQQ+LI+ +A + +AQ GSVR+GDAR+LATM LLI QS IQSA +V ILD+ AL
Sbjct 121 LGTSQQILIDAVAGEIKIAQEGGSVRAGDARQLATMCLLITQSAIQSAQMVAPILDADAL 180
Query 177 ATELTHALNGYL 188
A EL ++LNGYL
Sbjct 181 ARELAYSLNGYL 192
>gi|108800339|ref|YP_640536.1| TetR family transcriptional regulator [Mycobacterium sp. MCS]
gi|119869467|ref|YP_939419.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
gi|126435962|ref|YP_001071653.1| TetR family transcriptional regulator [Mycobacterium sp. JLS]
gi|108770758|gb|ABG09480.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS]
gi|119695556|gb|ABL92629.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
gi|126235762|gb|ABN99162.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS]
Length=193
Score = 207 bits (528), Expect = 5e-52, Method: Compositional matrix adjust.
Identities = 111/177 (63%), Positives = 136/177 (77%), Gaps = 2/177 (1%)
Query 14 RILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREV 73
RIL AAA CVV YGV+RVTLAEIARRA VSRPT+YRRW DT +++A++LT+ IA VL V
Sbjct 15 RILDAAAECVVAYGVNRVTLAEIARRARVSRPTIYRRWRDTDAVLAALLTARIAGVLDAV 74
Query 74 PLDGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAAR 131
P RE LV +IV V DRLR D+++++V+HS ELA VYITERLGTSQQ+LI+ LA
Sbjct 75 PGSAVGREPLVDRIVRVGDRLRNDEIVIAVLHSAPELAMVYITERLGTSQQILIDALAGE 134
Query 132 LTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYL 188
+ +AQ GSVRSG+ R+LA M LLI QSTIQSA +V +LD AL+ EL +LNGYL
Sbjct 135 IKLAQDEGSVRSGEPRQLAAMCLLITQSTIQSAQMVAPLLDEEALSVELARSLNGYL 191
>gi|333990283|ref|YP_004522897.1| transcriptional regulator [Mycobacterium sp. JDM601]
gi|333486251|gb|AEF35643.1| transcriptional regulatory protein [Mycobacterium sp. JDM601]
Length=192
Score = 205 bits (521), Expect = 3e-51, Method: Compositional matrix adjust.
Identities = 115/191 (61%), Positives = 141/191 (74%), Gaps = 3/191 (1%)
Query 1 MLSMSND-RADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMA 59
MLS SND + D G RIL AAASC++ GV+RVTLA IARRAGVSRPTVYRRWPD+RS++A
Sbjct 1 MLSTSNDEQVDVGDRILDAAASCLLALGVERVTLAAIARRAGVSRPTVYRRWPDSRSVIA 60
Query 60 SMLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMH--SELARVYITERL 117
++LT+ I D +V G R ALV +IVAVA R+R D ++M V+H ELA VYI ER+
Sbjct 61 ALLTARITDAWMQVRAPGSGRAALVDRIVAVAVRVRHDPVVMQVLHHAPELAMVYIAERM 120
Query 118 GTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALA 177
G SQ+ L++ +AA L AQ+ GSVR+G+ R+LA M LLI QS IQSA IV ILD ALA
Sbjct 121 GASQRHLVDVVAAELADAQQGGSVRAGEPRQLAAMCLLITQSAIQSAQIVAPILDEDALA 180
Query 178 TELTHALNGYL 188
ELT+ LN YL
Sbjct 181 AELTYNLNRYL 191
>gi|145223360|ref|YP_001134038.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
gi|145215846|gb|ABP45250.1| transcriptional regulator, TetR family [Mycobacterium gilvum
PYR-GCK]
Length=191
Score = 201 bits (512), Expect = 3e-50, Method: Compositional matrix adjust.
Identities = 108/190 (57%), Positives = 135/190 (72%), Gaps = 3/190 (1%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
M+S+ N RIL AAA C+ YGV+R T+ EIARRAGVSRPT+YRRWPD R ++A
Sbjct 1 MMSIRNSEP-VEQRILDAAAECIRAYGVERTTVTEIARRAGVSRPTIYRRWPDIRWVIAE 59
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLG 118
+LT I+DVL VP G RE LV ++V +A+ LR DD++MSV+ + LA VYITERLG
Sbjct 60 VLTVRISDVLAAVPAAGPGREELVDRVVRIAEHLRRDDIVMSVIFNAPTLAMVYITERLG 119
Query 119 TSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALAT 178
TSQQ+LI+ LAA + Q GSVR+GD ++ M LLIAQSTIQSA +V+ LD AL
Sbjct 120 TSQQLLIDTLAAAIVQGQAHGSVRAGDPHQMGAMCLLIAQSTIQSAQMVEKFLDRDALNA 179
Query 179 ELTHALNGYL 188
EL H+LNGYL
Sbjct 180 ELAHSLNGYL 189
>gi|120404719|ref|YP_954548.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii
PYR-1]
gi|119957537|gb|ABM14542.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii
PYR-1]
Length=192
Score = 197 bits (501), Expect = 7e-49, Method: Compositional matrix adjust.
Identities = 103/190 (55%), Positives = 134/190 (71%), Gaps = 2/190 (1%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
M+S+ N RIL AAA+C++ YGV+R T+ EIARRA VSRPT+YRRWPD R ++A
Sbjct 1 MVSIRNPERSVEQRILDAAAACILAYGVERTTMTEIARRARVSRPTIYRRWPDIRWVIAE 60
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHSE--LARVYITERLG 118
+LT I VL VP G RE++V ++VAVAD LR D+++ SV+ + LA YIT+RLG
Sbjct 61 LLTVRITGVLEAVPDRGAGRESVVGRVVAVADHLRADEIVQSVIRNAPGLAMTYITDRLG 120
Query 119 TSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALAT 178
TSQQ+LI+ LA + Q GS+R+GD R +A M LLI QSTIQSA +V +LD+ AL
Sbjct 121 TSQQILIDALAEAIKAGQDEGSIRAGDPRGMAAMCLLITQSTIQSAQMVAELLDNEALNE 180
Query 179 ELTHALNGYL 188
EL H+LNGYL
Sbjct 181 ELAHSLNGYL 190
>gi|315443819|ref|YP_004076698.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1]
gi|315262122|gb|ADT98863.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1]
Length=191
Score = 197 bits (500), Expect = 9e-49, Method: Compositional matrix adjust.
Identities = 106/190 (56%), Positives = 134/190 (71%), Gaps = 3/190 (1%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
M+S+ N RIL AAA C+ YGV+R T+ EIARRAGVSRPT+YRRWPD R ++A
Sbjct 1 MMSIRNSEP-VEQRILDAAAECIRAYGVERTTVTEIARRAGVSRPTIYRRWPDIRWVIAE 59
Query 61 MLTSHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLG 118
+LT I+DVL VP G RE LV ++V +A+ LR D+++MSV+ + LA VYITERLG
Sbjct 60 VLTVRISDVLAAVPAAGPGREELVDRVVRIAEHLRRDEIVMSVIFNAPTLAMVYITERLG 119
Query 119 TSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALAT 178
TSQQ+LI+ LAA + Q SVR+GD ++ M LLIAQSTIQSA +V+ LD AL
Sbjct 120 TSQQLLIDTLAAAIVQGQAHRSVRAGDPHQMGAMCLLIAQSTIQSAQMVEKFLDRDALNA 179
Query 179 ELTHALNGYL 188
EL H+LNGYL
Sbjct 180 ELAHSLNGYL 189
>gi|111023719|ref|YP_706691.1| TetR family transcriptional regulator [Rhodococcus jostii RHA1]
gi|110823249|gb|ABG98533.1| probable transcriptional regulator, TetR family protein [Rhodococcus
jostii RHA1]
Length=210
Score = 159 bits (402), Expect = 2e-37, Method: Compositional matrix adjust.
Identities = 86/177 (49%), Positives = 119/177 (68%), Gaps = 2/177 (1%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
IL AA SC++D+G+ R TLAE+ARRAGVSRPTVYRRW DTR+++A ++T IA V+ E
Sbjct 20 ILDAARSCILDFGLRRTTLAEVARRAGVSRPTVYRRWSDTRAVVADLMTREIAAVMPEFS 79
Query 75 LDGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAARL 132
++ LV +V V+ +R L + ++ S EL YI ERLGTSQ+ +I+ +A +
Sbjct 80 VEESVHRQLVDAVVHVSTEVRDHPLFVKILRSDQELFTTYILERLGTSQRAIIDQVAFAV 139
Query 133 TVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC 189
+ Q GS+R+GD+R +ATMVLLIAQS +QSA +V L AL +L HA+ YL
Sbjct 140 STGQDQGSIRAGDSRHIATMVLLIAQSAVQSAVMVAEELPGDALTEQLRHAVGAYLA 196
>gi|325672743|ref|ZP_08152439.1| TetR family transcriptional regulator [Rhodococcus equi ATCC
33707]
gi|325556620|gb|EGD26286.1| TetR family transcriptional regulator [Rhodococcus equi ATCC
33707]
Length=195
Score = 157 bits (398), Expect = 5e-37, Method: Compositional matrix adjust.
Identities = 91/194 (47%), Positives = 130/194 (68%), Gaps = 9/194 (4%)
Query 2 LSMSNDRADTGG---RILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIM 58
+S+ N+ +D +IL AA SCV+D+G+ R TLAE+ARRAGVSRPTVYRRWPDTR+++
Sbjct 1 MSICNELSDAPSVDDQILDAARSCVLDFGLRRTTLAEVARRAGVSRPTVYRRWPDTRAVV 60
Query 59 ASMLTSHIADVLREVPLDGDD--REALVKQIVAVADRLRGDDLIMSVMHS--ELARVYIT 114
A +LT I V+ + +DGD+ R LV+ +V VA +R L + ++ S +L YI
Sbjct 61 ADLLTREIRVVIPD--MDGDEPARVQLVRAVVEVATGMREHPLFVKILRSDPDLLMTYIV 118
Query 115 ERLGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSA 174
+RLGTSQ+ ++E ++ +T Q GS+R+GD +A MVLLIAQS +QSA +V +L
Sbjct 119 DRLGTSQRAIVERVSQAVTAGQIDGSIRAGDPVHIAAMVLLIAQSAVQSAGMVAEVLPPE 178
Query 175 ALATELTHALNGYL 188
AL EL A++ YL
Sbjct 179 ALTAELAVAVDTYL 192
>gi|312139376|ref|YP_004006712.1| tetr family transcriptional regulator [Rhodococcus equi 103S]
gi|311888715|emb|CBH48027.1| putative TetR family transcriptional regulator [Rhodococcus equi
103S]
Length=195
Score = 156 bits (395), Expect = 1e-36, Method: Compositional matrix adjust.
Identities = 91/194 (47%), Positives = 130/194 (68%), Gaps = 9/194 (4%)
Query 2 LSMSNDRADTGG---RILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIM 58
+S+ ND +D+ +IL AA SCV+D+G+ R TLAE+ARRAGVSRPTVYRRWPDTR+++
Sbjct 1 MSICNDLSDSPSVDDQILDAARSCVLDFGLRRTTLAEVARRAGVSRPTVYRRWPDTRAVV 60
Query 59 ASMLTSHIADVLREVPLDGDD--REALVKQIVAVADRLRGDDLIMSVMHS--ELARVYIT 114
A +LT I V+ + +DGD+ R LV+ +V VA +R L + ++ S +L YI
Sbjct 61 ADLLTREIRVVIPD--MDGDEPARVQLVRAVVEVATGMREHPLFVKILRSDPDLLMTYIV 118
Query 115 ERLGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSA 174
+RLGTSQ+ ++E ++ + Q GS+R+GD +A MVLLIAQS +QSA +V +L
Sbjct 119 DRLGTSQRAIVERVSQAVAAGQIDGSIRAGDRVHIAAMVLLIAQSAVQSAGMVAEVLPPE 178
Query 175 ALATELTHALNGYL 188
AL EL A++ YL
Sbjct 179 ALTAELAVAVDTYL 192
>gi|226366156|ref|YP_002783939.1| TetR family transcriptional regulator [Rhodococcus opacus B4]
gi|226244646|dbj|BAH54994.1| putative TetR family transcriptional regulator [Rhodococcus opacus
B4]
Length=222
Score = 155 bits (392), Expect = 2e-36, Method: Compositional matrix adjust.
Identities = 87/176 (50%), Positives = 118/176 (68%), Gaps = 2/176 (1%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
IL AA SC++D+G+ R TLAE+ARRAGVSRPTVYRRW DTR+++A ++T IA V+ E
Sbjct 33 ILDAARSCILDFGLRRTTLAEVARRAGVSRPTVYRRWSDTRAVVADLMTREIAAVMPEFS 92
Query 75 LDGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAARL 132
LV +V V+ +R L + ++ S EL YI ERLGTSQ+V+I+ +A +
Sbjct 93 TGESVHRQLVDAVVHVSTEVRDHPLFVKILRSDQELFTTYILERLGTSQRVIIDQVAVAV 152
Query 133 TVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYL 188
+ Q GS+R+GD+RR+ATMVLLIAQS +QSA +V L AL +L A+ YL
Sbjct 153 SAGQDQGSIRAGDSRRIATMVLLIAQSAVQSAVMVAEELPGDALTEQLRLAVGAYL 208
>gi|226306236|ref|YP_002766196.1| TetR family transcriptional regulator [Rhodococcus erythropolis
PR4]
gi|226185353|dbj|BAH33457.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis
PR4]
Length=212
Score = 147 bits (371), Expect = 7e-34, Method: Compositional matrix adjust.
Identities = 81/177 (46%), Positives = 112/177 (64%), Gaps = 2/177 (1%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
IL AA SCV+D+G+ R TLAEI+RRAGVSRPTVYRRWPDTR+++A +LT I VL EV
Sbjct 29 ILDAARSCVLDFGMQRTTLAEISRRAGVSRPTVYRRWPDTRAVVADLLTREIRSVLPEVT 88
Query 75 LDGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAARL 132
G LV+ I V ++R L + + H+ EL YI +RLG SQ+ ++E + + +
Sbjct 89 FTGSAATLLVEAIGDVVGQIRDHPLFVKIRHADQELLTTYIVDRLGASQKSILELITSVV 148
Query 133 TVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC 189
Q+ GS+R G +A MVLL+AQS + SA ++ L + A +L HA+ YL
Sbjct 149 AAGQQDGSIREGSVNEIAAMVLLMAQSVVISAPTLEPELSADASVEQLRHAVAAYLA 205
>gi|229490880|ref|ZP_04384715.1| regulatory protein, TetR [Rhodococcus erythropolis SK121]
gi|229322270|gb|EEN88056.1| regulatory protein, TetR [Rhodococcus erythropolis SK121]
Length=212
Score = 144 bits (364), Expect = 5e-33, Method: Compositional matrix adjust.
Identities = 80/177 (46%), Positives = 112/177 (64%), Gaps = 2/177 (1%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
IL AA SCV+D+G+ R TLAEI+RRAGVSRPTVYRRWPDTR+++A +LT I VL EV
Sbjct 29 ILDAARSCVLDFGMQRTTLAEISRRAGVSRPTVYRRWPDTRAVVADLLTREIRSVLPEVT 88
Query 75 LDGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAARL 132
+G LV+ I V ++R L + + + EL YI +RLG SQ+ ++E + + +
Sbjct 89 FNGSAGTLLVEAIGDVVGQIRDHPLFVKIRQADQELLTTYIVDRLGASQKSILELITSVV 148
Query 133 TVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC 189
Q+ GS+R G +A MVLL+AQS + SA ++ L S A +L +A+ YL
Sbjct 149 AAGQQDGSIREGSVNEIAAMVLLMAQSVVISAPTLEPELSSDASVEQLRYAVAAYLA 205
>gi|169630962|ref|YP_001704611.1| TetR family transcriptional regulator [Mycobacterium abscessus
ATCC 19977]
gi|169242929|emb|CAM63957.1| Putative transcriptional regulator, TetR family [Mycobacterium
abscessus]
Length=205
Score = 143 bits (361), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 82/179 (46%), Positives = 112/179 (63%), Gaps = 7/179 (3%)
Query 14 RILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREV 73
RIL AA SCV ++GV R TL E+A+RAGVSRP+VYRRWPD R+++A +LT + +L
Sbjct 28 RILDAALSCVTEFGVRRTTLVEVAKRAGVSRPSVYRRWPDVRTLVAELLTREMGSIL--- 84
Query 74 PLDGDD--REALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLA 129
P G RE LV+ + + ++R + +++ S EL YI +RLGTSQ+ LI A
Sbjct 85 PATGRGCARERLVRSVTGLVTQVREHSIFAAILRSDPELLLTYIVQRLGTSQRALIGWTA 144
Query 130 ARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYL 188
+ Q GS+R+G ++A MVLLI QS +QSA IV IL L EL A++GYL
Sbjct 145 MLIVEGQADGSIRAGIPEQMAAMVLLIGQSVLQSARIVADILSPDELVDELATAIDGYL 203
>gi|54023311|ref|YP_117553.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]
gi|54014819|dbj|BAD56189.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]
Length=222
Score = 143 bits (360), Expect = 1e-32, Method: Compositional matrix adjust.
Identities = 80/178 (45%), Positives = 110/178 (62%), Gaps = 3/178 (1%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVL-REV 73
I AA +CV ++GV R TL E+ARRAGVSRPTVYRRWPDT S++A +L + ++L
Sbjct 39 IFDAARACVAEFGVRRTTLTEVARRAGVSRPTVYRRWPDTGSLVAELLVRELREILGATT 98
Query 74 PLDGDDREALVKQIVAVADRLRGDDLIMSVMH--SELARVYITERLGTSQQVLIEGLAAR 131
P+ GD R LV +V A R+R + L + ++L Y+ RLG +Q+ LI+ AA
Sbjct 99 PVAGDGRARLVGSVVTGAARIRENPLFAKIFRTDTDLMLTYVFGRLGRNQRALIDLFAAG 158
Query 132 LTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC 189
+ Q GS+R G+ +LA M+LLIAQS +QSA V +L + L EL A+ GYL
Sbjct 159 IRAGQADGSIRPGEPVQLAAMLLLIAQSAVQSAGTVAGLLPADRLDAELGRAIEGYLA 216
>gi|343928708|ref|ZP_08768153.1| putative TetR family transcriptional regulator [Gordonia alkanivorans
NBRC 16433]
gi|343761457|dbj|GAA15079.1| putative TetR family transcriptional regulator [Gordonia alkanivorans
NBRC 16433]
Length=193
Score = 128 bits (321), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 82/190 (44%), Positives = 113/190 (60%), Gaps = 6/190 (3%)
Query 4 MSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLT 63
MS + G +L AA C++ G +VT++E+AR+AGVSRPTVYRRWPD I+ +LT
Sbjct 1 MSIRNEEIGDLVLDAARVCLLRSGGRKVTVSEVARQAGVSRPTVYRRWPDITEIIRDLLT 60
Query 64 SHIADVLREV---PLDGDDREALVKQIVAVADRLRGDDLIMSVMHSE--LARVYITERLG 118
+ ++ V + D +AL Q+V V LR DLI S+ + Y+ ERLG
Sbjct 61 REVLTIVDHVIGERGEPQDLDALADQVVTVVGALRDSDLISSLWREQRDFMAPYVFERLG 120
Query 119 TSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALAT 178
TSQQ ++ LA L Q VR+GDA+R+A+MVLLIAQS +QS +V IL + +T
Sbjct 121 TSQQGVLALLADMLAQGQGRKQVRAGDAKRMASMVLLIAQSFLQSGALVSDIL-AEGWST 179
Query 179 ELTHALNGYL 188
EL + GYL
Sbjct 180 ELHGVIAGYL 189
>gi|317509229|ref|ZP_07966850.1| tetR family bacterial regulatory protein [Segniliparus rugosus
ATCC BAA-974]
gi|316252439|gb|EFV11888.1| tetR family bacterial regulatory protein [Segniliparus rugosus
ATCC BAA-974]
Length=180
Score = 122 bits (306), Expect = 2e-26, Method: Compositional matrix adjust.
Identities = 76/178 (43%), Positives = 109/178 (62%), Gaps = 6/178 (3%)
Query 14 RILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREV 73
+IL AA C++ G R+TLA++ARRAGVSRPT+YRRW D ++ M+T +A +L +V
Sbjct 4 QILEAARDCLLS-GAARITLADVARRAGVSRPTIYRRWQDVNDLVRDMITREVAGLLEQV 62
Query 74 -PLDGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAA 130
P DG R LV++IVA A D L+ ++ EL Y+ +R+GTSQ+ +++ L
Sbjct 63 GPGDG-RRADLVRRIVAFARAAHEDQLLRVLLDERRELLATYVFQRIGTSQRSVLKVLRE 121
Query 131 RLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYL 188
+ +QR G VR GD LA M L++AQS QS +++ +L A EL LNGYL
Sbjct 122 EIEQSQRLGEVREGDPEELAMMTLVLAQSVTQSTRLLEPVLHE-RWADELARVLNGYL 178
>gi|297559284|ref|YP_003678258.1| TetR family transcriptional regulator [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
gi|296843732|gb|ADH65752.1| transcriptional regulator, TetR family [Nocardiopsis dassonvillei
subsp. dassonvillei DSM 43111]
Length=200
Score = 119 bits (297), Expect = 3e-25, Method: Compositional matrix adjust.
Identities = 74/183 (41%), Positives = 102/183 (56%), Gaps = 8/183 (4%)
Query 14 RILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREV 73
RIL AA +CV +GV R TL ++ARRAGVSRPTVYRRWPD +++A +LT + +L +
Sbjct 10 RILDAARACVEAFGVRRTTLTDVARRAGVSRPTVYRRWPDATALVADLLTRELRRILADQ 69
Query 74 ------PLDGDDREALVKQIVAVADRLRGDDLIMSVM--HSELARVYITERLGTSQQVLI 125
P D R LV+ VA L L + ++ EL Y +RLGTS + +
Sbjct 70 GDGPGGPAGEDVRARLVRHAAGVARALLAHPLFVRIVDTEPELLATYTFQRLGTSHRAAL 129
Query 126 EGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALN 185
E + + QR GSVR+GD LA +VL+ Q T+ S + + D + L EL L+
Sbjct 130 ELVEPVVAEGQRDGSVRAGDPAVLARLVLVTVQGTVTSRRLFADVTDESGLVDELAALLD 189
Query 186 GYL 188
GYL
Sbjct 190 GYL 192
>gi|111221025|ref|YP_711819.1| TetR family transcriptional regulator [Frankia alni ACN14a]
gi|111148557|emb|CAJ60230.1| putative TetR-family transcriptional regulator [Frankia alni
ACN14a]
Length=232
Score = 118 bits (296), Expect = 4e-25, Method: Compositional matrix adjust.
Identities = 74/184 (41%), Positives = 107/184 (59%), Gaps = 9/184 (4%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
+L AA + ++ GV R TL E+ARRAGVSR T+YRRWPD RS++ ++T V+
Sbjct 26 VLDAAKASLLAVGVRRTTLTEVARRAGVSRMTLYRRWPDLRSLVGDVMTREWTRVVTAAA 85
Query 75 L-------DGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLI 125
G D + LV I+A + R + + + ++ + EL Y+TER G +QQ++I
Sbjct 86 ARPTAPDRSGGDLDDLVDHIIATVEAFRTNPVYLRIIETDPELLLPYLTERRGATQQMII 145
Query 126 EGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALN 185
+ LA +L A RSG+VR + LA MVLL+ QS + SAD + + +A LA EL L
Sbjct 146 DLLAGQLDAAARSGTVRPVEPAALAVMVLLVVQSFVLSADALAGPVPAATLAAELRRLLR 205
Query 186 GYLC 189
GYL
Sbjct 206 GYLA 209
>gi|158317350|ref|YP_001509858.1| TetR family transcriptional regulator [Frankia sp. EAN1pec]
gi|158112755|gb|ABW14952.1| transcriptional regulator, TetR family [Frankia sp. EAN1pec]
Length=279
Score = 109 bits (273), Expect = 2e-22, Method: Compositional matrix adjust.
Identities = 68/171 (40%), Positives = 97/171 (57%), Gaps = 8/171 (4%)
Query 27 GVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLR------EVPLDGDDR 80
GV R T ++ARRAGVSR T+YRRWPD RS++ ++T ++ E L R
Sbjct 61 GVRRTTATDVARRAGVSRMTLYRRWPDLRSLVGDVMTREWGRIVTAAARAAEPSLAAGTR 120
Query 81 EALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLAARLTVAQRS 138
LV+ +V A R + L ++ + EL Y+ ERLG +Q++++E L +L AQ
Sbjct 121 AGLVRYLVTAAQTFRANPLFRKIIETDPELLVPYVLERLGATQRLVLELLCEQLREAQAG 180
Query 139 GSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYLC 189
G+VR+GD A MVLL+ QS + SAD + + ALA EL L+GYL
Sbjct 181 GAVRAGDPAAQARMVLLVVQSYVLSADALGDEITEEALARELYLTLDGYLA 231
>gi|145595106|ref|YP_001159403.1| regulatory protein TetR [Salinispora tropica CNB-440]
gi|145304443|gb|ABP55025.1| regulatory protein, TetR [Salinispora tropica CNB-440]
Length=197
Score = 107 bits (267), Expect = 8e-22, Method: Compositional matrix adjust.
Identities = 71/179 (40%), Positives = 103/179 (58%), Gaps = 5/179 (2%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
+L AA CV+ YGV R T+ ++ARRAGVSR TVYRRWPD +S++ ++T VL
Sbjct 16 VLDAARDCVLAYGVRRTTVTDVARRAGVSRMTVYRRWPDVQSLIGDLMTREWQQVLLAAA 75
Query 75 LD---GDDREALVKQIVAVADRLRGDDLIMSV--MHSELARVYITERLGTSQQVLIEGLA 129
D G R LV+++VA A LR L+ + + E+ Y+ +R G Q+ ++ L
Sbjct 76 TDEGTGHARSRLVERVVAGARVLREHPLLCKIRDVDPEVLIPYLLDRRGAGQEEMLRFLV 135
Query 130 ARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYL 188
+ + GSVRSG+A +A +VLL QS + SA V L +A+L EL ++GYL
Sbjct 136 DAVAHGRADGSVRSGEAETMARVVLLTTQSFVLSARTVADGLPAASLDRELARLVDGYL 194
>gi|331698318|ref|YP_004334557.1| regulatory protein TetR [Pseudonocardia dioxanivorans CB1190]
gi|326953007|gb|AEA26704.1| regulatory protein TetR [Pseudonocardia dioxanivorans CB1190]
Length=186
Score = 106 bits (264), Expect = 2e-21, Method: Compositional matrix adjust.
Identities = 79/187 (43%), Positives = 107/187 (58%), Gaps = 5/187 (2%)
Query 4 MSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLT 63
MS R D G +L AA +CV+D GV R TLA++ARRAGVSR ++YRRW ++ +LT
Sbjct 1 MSTVRLDDGA-VLDAARACVLDVGVRRTTLADVARRAGVSRMSLYRRWSGIDELVGDVLT 59
Query 64 SHIADVLREVPLDGDDREALVKQIVAVADRLRGDDLIMSV--MHSELARVYITERLGTSQ 121
+ L LDG DR ALV ++V V + LR L+ + + EL Y+ R G S
Sbjct 60 REL-HTLTGDALDG-DRAALVARVVEVCEALRRHGLVRKIVDVDPELLLPYVLRRRGRST 117
Query 122 QVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELT 181
+ +++ L + AQ G+VR GDA LA VLL AQS + SA V + +A L EL
Sbjct 118 EAIVDRLTVAILAAQAGGTVRQGDAGLLARFVLLTAQSYVLSAGAVAADAPAAGLPGELA 177
Query 182 HALNGYL 188
L+GYL
Sbjct 178 TLLDGYL 184
>gi|86739655|ref|YP_480055.1| TetR family transcriptional regulator [Frankia sp. CcI3]
gi|86566517|gb|ABD10326.1| transcriptional regulator, TetR family [Frankia sp. CcI3]
Length=208
Score = 101 bits (252), Expect = 5e-20, Method: Compositional matrix adjust.
Identities = 67/191 (36%), Positives = 103/191 (54%), Gaps = 19/191 (9%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
+L AA + ++ GV R TL E+ARRAGVSR T+YRRWPD RS++ ++T V+
Sbjct 9 VLDAAKASLLAVGVRRTTLTEVARRAGVSRMTLYRRWPDLRSLVGDVMTREWTQVVTAAS 68
Query 75 LDG--------------DDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLG 118
DD LV+ I+A + R + L + ++ + EL Y+ ER G
Sbjct 69 AMAQAGPDGGPPDGGLVDD---LVEHIIATVEAFRTNPLYLRIIETDPELLIPYLIERRG 125
Query 119 TSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALAT 178
+QQ++++ L ++ A+ +G+VR D LA MVLL+ QS + SA+ + + +A
Sbjct 126 ATQQMILDLLTSQFRTAEANGAVRPEDPSALALMVLLVVQSFVLSAEALGCGVPAATRTA 185
Query 179 ELTHALNGYLC 189
EL L GYL
Sbjct 186 ELRRLLRGYLA 196
>gi|159038349|ref|YP_001537602.1| TetR family transcriptional regulator [Salinispora arenicola
CNS-205]
gi|157917184|gb|ABV98611.1| transcriptional regulator, TetR family [Salinispora arenicola
CNS-205]
Length=197
Score = 100 bits (249), Expect = 9e-20, Method: Compositional matrix adjust.
Identities = 69/179 (39%), Positives = 98/179 (55%), Gaps = 5/179 (2%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
+L AA CV+ YGV R T+ ++ARRAGVSR TVYRRWPD +S++ ++T VL
Sbjct 16 VLDAAGDCVLAYGVRRTTVTDVARRAGVSRMTVYRRWPDVQSMIGDLMTREWQRVLLATA 75
Query 75 L---DGDDREALVKQIVAVADRLRGDDLIMSV--MHSELARVYITERLGTSQQVLIEGLA 129
DG R LV ++VA A +R L+ + + E+ Y+ +R G Q+ ++ L
Sbjct 76 ADEGDGHARSRLVARVVAGARVMREHPLLCKIRDVDPEVLIPYLFDRRGAGQEDMLRFLV 135
Query 130 ARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYL 188
A + GSVR GDA +A MV L QS + SA V + A+ EL ++GYL
Sbjct 136 AAVADGAADGSVRPGDAEVMARMVFLTTQSFVLSARTVVDGVSFASFDRELARLVDGYL 194
>gi|262204636|ref|YP_003275844.1| TetR family transcriptional regulator [Gordonia bronchialis DSM
43247]
gi|262087983|gb|ACY23951.1| regulatory protein TetR [Gordonia bronchialis DSM 43247]
Length=211
Score = 100 bits (249), Expect = 1e-19, Method: Compositional matrix adjust.
Identities = 78/194 (41%), Positives = 104/194 (54%), Gaps = 10/194 (5%)
Query 4 MSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLT 63
MS + G +L AA C++ RVT++E+AR AGVSRPTVYRRW D I+ ++LT
Sbjct 1 MSIRNEEIGDLVLDAARRCLIRSAGRRVTVSEVAREAGVSRPTVYRRWLDITGIVRTLLT 60
Query 64 SHIADVLREV-------PLDGDDREALVKQIVAVADRLRGDDLIMSVMHSE--LARVYIT 114
+ + V G + L IV V LR + LI S+ + Y+
Sbjct 61 REVLGTVEGVVGGRLTDSSAGPGIDDLPGAIVEVVAALRANQLISSLWQEQRDFMAPYMF 120
Query 115 ERLGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSA 174
ERLGTSQQ ++ LA L AQ VR GD +++A MVLLIAQS +QS +V IL +
Sbjct 121 ERLGTSQQGVLALLADLLAQAQTRALVRPGDTKQMAAMVLLIAQSFLQSGALVSDIL-AD 179
Query 175 ALATELTHALNGYL 188
EL H + GYL
Sbjct 180 DWRPELRHVIAGYL 193
>gi|300790225|ref|YP_003770516.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
U32]
gi|299799739|gb|ADJ50114.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
U32]
gi|340531906|gb|AEK47111.1| TetR family transcriptional regulator [Amycolatopsis mediterranei
S699]
Length=187
Score = 99.4 bits (246), Expect = 2e-19, Method: Compositional matrix adjust.
Identities = 73/180 (41%), Positives = 94/180 (53%), Gaps = 6/180 (3%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
+L AA SCV+ GV R TLAEIAR A VSR TVYRR+PD RS++A+++T + +LR
Sbjct 6 LLDAARSCVLAVGVRRTTLAEIARTARVSRMTVYRRFPDVRSVLAALMTREFSGLLRTAS 65
Query 75 LDGDD----REALVKQIVAVADRLRGDDLIMSVM--HSELARVYITERLGTSQQVLIEGL 128
G D R LV A L D L +++ EL YI ERLG +Q+ + L
Sbjct 66 EGGADAAHSRARLVLIAAAGVRALSTDPLFRTLLDVDPELVLPYIVERLGATQKFAEQAL 125
Query 129 AARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYL 188
A L R GS+R + VLL+ QS S +D AAL E TH L+ L
Sbjct 126 HALLDAGHRDGSIRRAPVAVQSRSVLLVVQSFAFSLRPATVDVDEAALMAEFTHVLDAAL 185
>gi|269126039|ref|YP_003299409.1| TetR family transcriptional regulator [Thermomonospora curvata
DSM 43183]
gi|268310997|gb|ACY97371.1| transcriptional regulator, TetR family [Thermomonospora curvata
DSM 43183]
Length=197
Score = 96.7 bits (239), Expect = 1e-18, Method: Compositional matrix adjust.
Identities = 67/160 (42%), Positives = 85/160 (54%), Gaps = 7/160 (4%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
+L AA CV+ GV R TL +IARRAGVSR T+YRRWPD RSI+A ++T + E+
Sbjct 14 VLDAARECVLAVGVRRTTLTDIARRAGVSRMTLYRRWPDVRSIVADLMTREWTALAAEIS 73
Query 75 LDGDD-----REALVKQIVAVADRLRGDDLIMSV--MHSELARVYITERLGTSQQVLIEG 127
G D R ALV +V LR L+ + + EL Y+ R G SQ+
Sbjct 74 AAGRDASGPARRALVDNLVEGVRALRDHPLLRKIVDVDPELLLPYVLHRQGASQRAFCRI 133
Query 128 LAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIV 167
L + GS+R GD R A +LLIAQS SA IV
Sbjct 134 LEEAVRAGHADGSIRRGDPVRQARALLLIAQSFALSAPIV 173
>gi|308372188|ref|ZP_07667325.1| LOW QUALITY PROTEIN: putative transcriptional regulator, TetR
family [Mycobacterium tuberculosis SUMu004]
gi|308334085|gb|EFP22936.1| LOW QUALITY PROTEIN: putative transcriptional regulator, TetR
family [Mycobacterium tuberculosis SUMu004]
Length=47
Score = 95.9 bits (237), Expect = 3e-18, Method: Compositional matrix adjust.
Identities = 46/47 (98%), Positives = 47/47 (100%), Gaps = 0/47 (0%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASM 61
+LRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASM
Sbjct 1 MLRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASM 47
>gi|134097268|ref|YP_001102929.1| TetR family transcriptional regulator [Saccharopolyspora erythraea
NRRL 2338]
gi|291009466|ref|ZP_06567439.1| TetR family transcriptional regulator [Saccharopolyspora erythraea
NRRL 2338]
gi|133909891|emb|CAM00003.1| TetR-family transcriptional regulator [Saccharopolyspora erythraea
NRRL 2338]
Length=243
Score = 95.1 bits (235), Expect = 4e-18, Method: Compositional matrix adjust.
Identities = 67/179 (38%), Positives = 97/179 (55%), Gaps = 5/179 (2%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVL---R 71
+L AA CV+D GV R TLAEIARRA VSR T+YRR+PD S++ +++T+ A++L R
Sbjct 57 LLTAARECVLDLGVRRSTLAEIARRARVSRMTLYRRFPDVDSLVTALMTTEFAEILHHAR 116
Query 72 EVPLDGDDREALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQVLIEGLA 129
G R LV ++ LR L+ V+ + EL Y+ E+LG++Q L
Sbjct 117 AAEGTGSARNRLVNAVLRCVRLLRSAPLLRRVLETDAELLLPYLVEQLGSTQLAAERFLR 176
Query 130 ARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYL 188
L GS+R D + +L+ QS + S ++ +D AALA EL H L+ L
Sbjct 177 DYLVQGHLDGSIRRADPAAQSRALLMTLQSFVVSTGPAETGVDPAALAEELAHLLDAAL 235
>gi|302530478|ref|ZP_07282820.1| TetR-family transcriptional regulator [Streptomyces sp. AA4]
gi|302439373|gb|EFL11189.1| TetR-family transcriptional regulator [Streptomyces sp. AA4]
Length=214
Score = 94.7 bits (234), Expect = 5e-18, Method: Compositional matrix adjust.
Identities = 70/180 (39%), Positives = 93/180 (52%), Gaps = 6/180 (3%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
+L AA CV+ GV R TLAEIAR A VSR TVYRR+PD RS++A+++T + +L+ V
Sbjct 33 LLDAARQCVLAVGVRRTTLAEIARTAQVSRMTVYRRFPDVRSVLAALMTREFSGLLQRVN 92
Query 75 LDGDD----REALVKQIVAVADRLRGDDLIMSVM--HSELARVYITERLGTSQQVLIEGL 128
GD R+ +V A L D L +++ +EL YI ERLG +Q L
Sbjct 93 ETGDQTAHARDRIVHLAAASVGALSADPLFRTLLDVDAELVLPYIVERLGATQHFAEHVL 152
Query 129 AARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALNGYL 188
+ L R GSVR A VLL+ QS S + +D AAL E H + L
Sbjct 153 RSLLEEGHRDGSVRVAGVAAQARSVLLVVQSFAFSLRPATADVDEAALLAEFRHLVEAGL 212
>gi|288923564|ref|ZP_06417677.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
gi|288345085|gb|EFC79501.1| transcriptional regulator, TetR family [Frankia sp. EUN1f]
Length=283
Score = 94.7 bits (234), Expect = 6e-18, Method: Compositional matrix adjust.
Identities = 73/187 (40%), Positives = 107/187 (58%), Gaps = 12/187 (6%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
+L AAA+ ++ GV R TLAE+AR+AGVSR T+YRRWPD RS++ +++ A ++
Sbjct 67 VLDAAAALLMTIGVRRTTLAEVARQAGVSRMTLYRRWPDLRSLVRDVMSREWARIVVPGA 126
Query 75 LDGDD----------REALVKQIVAVADRLRGDDLIMSVMHS--ELARVYITERLGTSQQ 122
+ D R LV+ +VA A + + L + + + EL YI ERLGT+Q
Sbjct 127 MAAGDGKAGTDPAATRAELVRSLVATAQAFQANPLFLRICATDGELLAPYILERLGTTQL 186
Query 123 VLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTH 182
++++ L RL A+ G+VR+GD A MVLL QS + SA + + ALA EL
Sbjct 187 LVLDLLRERLAAARAVGAVRAGDPAAQARMVLLATQSYVLSAGALGDEVSRDALAQELYL 246
Query 183 ALNGYLC 189
L+GYL
Sbjct 247 MLDGYLA 253
>gi|257057287|ref|YP_003135119.1| transcriptional regulator [Saccharomonospora viridis DSM 43017]
gi|256587159|gb|ACU98292.1| transcriptional regulator [Saccharomonospora viridis DSM 43017]
Length=212
Score = 91.3 bits (225), Expect = 6e-17, Method: Compositional matrix adjust.
Identities = 71/183 (39%), Positives = 100/183 (55%), Gaps = 12/183 (6%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADVLREVP 74
+L AA +CV+ GV R TL +IAR AGVSR T+YRR+PD RS++A+++T +LR V
Sbjct 31 LLDAARTCVLTTGVRRTTLTDIARTAGVSRMTLYRRFPDVRSVLAALMTREFGALLRRVT 90
Query 75 LDGDD----REALVKQIVAVADRLRGDDLIMSVM--HSELARVYITERLGTSQ---QVLI 125
+ D R LV+ A L D L+ +V+ +EL YITERLG++Q + ++
Sbjct 91 AEIDTALPARRRLVELGTAAVRALTTDPLLRTVLDKDAELLLPYITERLGSTQLLAEDVV 150
Query 126 EGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQSADIVDSILDSAALATELTHALN 185
+GL + GSVR G A +LL QS I S + AL +EL H L+
Sbjct 151 DGL---VRAGHADGSVRRGKPEVQARALLLTVQSFILSWRPATENVPDEALLSELRHLLD 207
Query 186 GYL 188
L
Sbjct 208 RSL 210
>gi|21219199|ref|NP_624978.1| TetR family transcriptional regulator [Streptomyces coelicolor
A3(2)]
gi|289773663|ref|ZP_06533041.1| TetR family transcriptional regulator [Streptomyces lividans
TK24]
gi|6434739|emb|CAB61186.1| putative TetR-family transcriptional regulator [Streptomyces
coelicolor A3(2)]
gi|289703862|gb|EFD71291.1| TetR family transcriptional regulator [Streptomyces lividans
TK24]
Length=205
Score = 90.9 bits (224), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 69/176 (40%), Positives = 91/176 (52%), Gaps = 10/176 (5%)
Query 15 ILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMASMLTSHIADV----L 70
+L A CV+ GV R T+ ++ARRAGVSR T+YRRWPD RS++ ++T V +
Sbjct 20 VLDAVRDCVLAVGVRRTTMTDVARRAGVSRMTLYRRWPDVRSLVGDLMTREWIAVATGAV 79
Query 71 REVPLDGDDREALVKQIVAVADRLRGDDLIMSV--MHSELARVYITERLGTSQQVLIEGL 128
E D D R +V+ +VA R L + + EL Y+ +R G SQ+ L+E L
Sbjct 80 TEPGQDTDARSRMVEGLVAGVAAFRAHPLFRKIVDVDPELLLPYVLDRRGASQEALLELL 139
Query 129 AARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQS----ADIVDSILDSAALATEL 180
A L GSVR R A VLL+ QS S AD D+ L AAL EL
Sbjct 140 ADSLEEGHADGSVRRTHTGRQARSVLLVVQSFALSLRTMADEDDAELTPAALLAEL 195
>gi|291441483|ref|ZP_06580873.1| TetR-family transcriptional regulator [Streptomyces ghanaensis
ATCC 14672]
gi|291344378|gb|EFE71334.1| TetR-family transcriptional regulator [Streptomyces ghanaensis
ATCC 14672]
Length=199
Score = 89.4 bits (220), Expect = 3e-16, Method: Compositional matrix adjust.
Identities = 75/203 (37%), Positives = 97/203 (48%), Gaps = 19/203 (9%)
Query 1 MLSMSNDRADTGGRILRAAASCVVDYGVDRVTLAEIARRAGVSRPTVYRRWPDTRSIMAS 60
M + ++R+D +L A CV+ GV R TL ++ARRAGVSR T+YRRWPD RS++
Sbjct 1 MTPIRHNRSDNDA-VLDAVRDCVLAVGVRRTTLTDVARRAGVSRMTLYRRWPDVRSLVGD 59
Query 61 MLTSHIADV----LRE----VPLDGDDREALVKQIVAVADRLRGDDLIMSVMH--SELAR 110
++T V + E PL G LV +VA L L ++ EL
Sbjct 60 LMTREWIGVATAAMPERRPGTPLRG----PLVDGLVAAVRALGEHPLFRKILEVDPELLL 115
Query 111 VYITERLGTSQQVLIEGLAARLTVAQRSGSVRSGDARRLATMVLLIAQSTIQS----ADI 166
Y+ +R G SQ L++ LA L GSVR R A VLLIAQS S D
Sbjct 116 PYVLDRRGASQDTLLQLLADALREGHADGSVRVEHTERQARAVLLIAQSFTLSLRTMTDE 175
Query 167 VDSILDSAALATELTHALNGYLC 189
D L + A EL H L L
Sbjct 176 DDPDLTTEAFLAELRHTLERTLA 198
Lambda K H
0.321 0.132 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 187037746340
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40