BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2263 Length=317 Score E Sequences producing significant alignments: (Bits) Value gi|15609400|ref|NP_216779.1| short chain dehydrogenase [Mycobact... 636 1e-180 gi|289443773|ref|ZP_06433517.1| oxidoreductase [Mycobacterium tu... 634 5e-180 gi|340627269|ref|YP_004745721.1| putative oxidoreductase [Mycoba... 634 8e-180 gi|183983345|ref|YP_001851636.1| oxidoreductase [Mycobacterium m... 573 1e-161 gi|118616988|ref|YP_905320.1| short chain dehydrogenase [Mycobac... 572 3e-161 gi|240170101|ref|ZP_04748760.1| short chain dehydrogenase [Mycob... 565 4e-159 gi|296166151|ref|ZP_06848596.1| short-chain dehydrogenase/reduct... 501 7e-140 gi|254551308|ref|ZP_05141755.1| short chain dehydrogenase [Mycob... 499 2e-139 gi|254818826|ref|ZP_05223827.1| short chain dehydrogenase [Mycob... 413 2e-113 gi|41407566|ref|NP_960402.1| short chain dehydrogenase [Mycobact... 394 9e-108 gi|118466655|ref|YP_882155.1| short chain dehydrogenase [Mycobac... 392 4e-107 gi|342861353|ref|ZP_08718001.1| short chain dehydrogenase [Mycob... 391 8e-107 gi|317509010|ref|ZP_07966641.1| short chain dehydrogenase [Segni... 384 9e-105 gi|254775441|ref|ZP_05216957.1| short chain dehydrogenase [Mycob... 367 2e-99 gi|289750860|ref|ZP_06510238.1| oxidoreductase [Mycobacterium tu... 365 4e-99 gi|158315370|ref|YP_001507878.1| short chain dehydrogenase [Fran... 323 2e-86 gi|229822648|ref|YP_002884174.1| short chain dehydrogenase [Beut... 322 5e-86 gi|84495943|ref|ZP_00994797.1| short chain dehydrogenase [Janiba... 311 1e-82 gi|289758388|ref|ZP_06517766.1| hypothetical protein TBEG_01067 ... 310 2e-82 gi|291454342|ref|ZP_06593732.1| short chain dehydrogenase [Strep... 308 7e-82 gi|297561321|ref|YP_003680295.1| short-chain dehydrogenase/reduc... 308 7e-82 gi|256378491|ref|YP_003102151.1| short-chain dehydrogenase/reduc... 307 1e-81 gi|126347794|emb|CAJ89514.1| putative oxidoreductase [Streptomyc... 303 2e-80 gi|294993497|ref|ZP_06799188.1| short chain dehydrogenase [Mycob... 300 2e-79 gi|120402076|ref|YP_951905.1| short chain dehydrogenase [Mycobac... 300 3e-79 gi|169630153|ref|YP_001703802.1| short chain dehydrogenase [Myco... 296 2e-78 gi|329937548|ref|ZP_08287106.1| short chain dehydrogenase [Strep... 296 3e-78 gi|296138432|ref|YP_003645675.1| short-chain dehydrogenase/reduc... 295 8e-78 gi|152966532|ref|YP_001362316.1| short chain dehydrogenase [Kine... 292 5e-77 gi|326333015|ref|ZP_08199271.1| oxidoreductase, short-chain dehy... 291 9e-77 gi|258654166|ref|YP_003203322.1| short chain dehydrogenase [Naka... 291 1e-76 gi|255034640|ref|YP_003085261.1| short-chain dehydrogenase/reduc... 290 1e-76 gi|332671412|ref|YP_004454420.1| short-chain dehydrogenase/reduc... 286 4e-75 gi|324998759|ref|ZP_08119871.1| short chain dehydrogenase [Pseud... 285 6e-75 gi|295689815|ref|YP_003593508.1| short-chain dehydrogenase/reduc... 285 7e-75 gi|284042532|ref|YP_003392872.1| short-chain dehydrogenase/reduc... 283 3e-74 gi|118468364|ref|YP_886565.1| short chain dehydrogenase [Mycobac... 282 4e-74 gi|297560298|ref|YP_003679272.1| short-chain dehydrogenase/reduc... 280 2e-73 gi|222084742|ref|YP_002543271.1| oxidoreductase protein [Agrobac... 280 2e-73 gi|296160842|ref|ZP_06843655.1| short-chain dehydrogenase/reduct... 280 2e-73 gi|284028017|ref|YP_003377948.1| short-chain dehydrogenase/reduc... 279 4e-73 gi|27376364|ref|NP_767893.1| dehydrogenase [Bradyrhizobium japon... 276 3e-72 gi|114800019|ref|YP_760917.1| short chain dehydrogenase/reductas... 275 8e-72 gi|115524813|ref|YP_781724.1| short-chain dehydrogenase/reductas... 271 1e-70 gi|339024785|ref|ZP_08646691.1| oxidoreductase [Acetobacter trop... 270 2e-70 gi|152966462|ref|YP_001362246.1| short chain dehydrogenase [Kine... 269 5e-70 gi|269126055|ref|YP_003299425.1| short-chain dehydrogenase/reduc... 268 9e-70 gi|299139839|ref|ZP_07033011.1| short-chain dehydrogenase/reduct... 267 2e-69 gi|159186572|ref|NP_396225.2| dehydrogenase [Agrobacterium tumef... 267 2e-69 gi|330809739|ref|YP_004354201.1| short chain dehydrogenase [Pseu... 266 3e-69 >gi|15609400|ref|NP_216779.1| short chain dehydrogenase [Mycobacterium tuberculosis H37Rv] gi|15841754|ref|NP_336791.1| short chain dehydrogenase [Mycobacterium tuberculosis CDC1551] gi|31793442|ref|NP_855935.1| short chain dehydrogenase [Mycobacterium bovis AF2122/97] 65 more sequence titles Length=317 Score = 636 bits (1640), Expect = 1e-180, Method: Compositional matrix adjust. Identities = 317/317 (100%), Positives = 317/317 (100%), Gaps = 0/317 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT Sbjct 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF Sbjct 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK Sbjct 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF Sbjct 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR Sbjct 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 Query 301 LWEVSEQLTGVSYPKSR 317 LWEVSEQLTGVSYPKSR Sbjct 301 LWEVSEQLTGVSYPKSR 317 >gi|289443773|ref|ZP_06433517.1| oxidoreductase [Mycobacterium tuberculosis T46] gi|289570382|ref|ZP_06450609.1| oxidoreductase [Mycobacterium tuberculosis T17] gi|289416692|gb|EFD13932.1| oxidoreductase [Mycobacterium tuberculosis T46] gi|289544136|gb|EFD47784.1| oxidoreductase [Mycobacterium tuberculosis T17] Length=317 Score = 634 bits (1635), Expect = 5e-180, Method: Compositional matrix adjust. Identities = 316/317 (99%), Positives = 316/317 (99%), Gaps = 0/317 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT Sbjct 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF Sbjct 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK Sbjct 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF Sbjct 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREA VPAAARNDADSKR Sbjct 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREATVPAAARNDADSKR 300 Query 301 LWEVSEQLTGVSYPKSR 317 LWEVSEQLTGVSYPKSR Sbjct 301 LWEVSEQLTGVSYPKSR 317 >gi|340627269|ref|YP_004745721.1| putative oxidoreductase [Mycobacterium canettii CIPT 140010059] gi|340005459|emb|CCC44619.1| putative oxidoreductase [Mycobacterium canettii CIPT 140010059] Length=317 Score = 634 bits (1634), Expect = 8e-180, Method: Compositional matrix adjust. Identities = 316/317 (99%), Positives = 316/317 (99%), Gaps = 0/317 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 MAKDLVATVP LSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT Sbjct 1 MAKDLVATVPALSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF Sbjct 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK Sbjct 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF Sbjct 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR Sbjct 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 Query 301 LWEVSEQLTGVSYPKSR 317 LWEVSEQLTGVSYPKSR Sbjct 301 LWEVSEQLTGVSYPKSR 317 >gi|183983345|ref|YP_001851636.1| oxidoreductase [Mycobacterium marinum M] gi|183176671|gb|ACC41781.1| oxidoreductase [Mycobacterium marinum M] Length=317 Score = 573 bits (1478), Expect = 1e-161, Method: Compositional matrix adjust. Identities = 279/316 (89%), Positives = 300/316 (95%), Gaps = 0/316 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 MA DL+ATVPDLSGKLAI+TGANSGLGFGLARRLSAAGADV+MAIRNRAKGEAA+EEIR+ Sbjct 1 MASDLIATVPDLSGKLAIVTGANSGLGFGLARRLSAAGADVVMAIRNRAKGEAAIEEIRS 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 AVPDAKL+IKALDLSSLASVAALG+QL ++GRPID+LINNAGVMTPPER TTADGFELQF Sbjct 61 AVPDAKLSIKALDLSSLASVAALGDQLNSEGRPIDILINNAGVMTPPERDTTADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 GSNHLGHFALTAH+LPLLRAAQ ARVVSLSSLAARRGRIHFDDLQFE+SYA MTAYGQSK Sbjct 121 GSNHLGHFALTAHVLPLLRAAQGARVVSLSSLAARRGRIHFDDLQFEKSYAAMTAYGQSK 180 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LAVLMFARELDRRSRAAGWG++SNAAHPGLTKTNLQI+GPSHGR+KPALM+R Y TSWRF Sbjct 181 LAVLMFARELDRRSRAAGWGVMSNAAHPGLTKTNLQISGPSHGREKPALMQRFYTTSWRF 240 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 APFLWQEIE+GILPALYAA TPQA+GGAFYGPRG YE AGGGVR AKVPA A NDAD +R Sbjct 241 APFLWQEIEDGILPALYAAVTPQAEGGAFYGPRGFYEAAGGGVRAAKVPARAGNDADCQR 300 Query 301 LWEVSEQLTGVSYPKS 316 LWEVSE+LTGV YP S Sbjct 301 LWEVSERLTGVGYPTS 316 >gi|118616988|ref|YP_905320.1| short chain dehydrogenase [Mycobacterium ulcerans Agy99] gi|118569098|gb|ABL03849.1| oxidoreductase [Mycobacterium ulcerans Agy99] Length=317 Score = 572 bits (1473), Expect = 3e-161, Method: Compositional matrix adjust. Identities = 278/316 (88%), Positives = 299/316 (95%), Gaps = 0/316 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 MA DL+ATVPDLSGKLAI+TGANSGLGFGLARRLSAAGADV+MAIRNRAKGEAA+EEIR+ Sbjct 1 MASDLIATVPDLSGKLAIVTGANSGLGFGLARRLSAAGADVVMAIRNRAKGEAAIEEIRS 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 AVPDAKL+ KALDLSSLASVAALG+QL ++GRPID+LINNAGVMTPPER TTADGFELQF Sbjct 61 AVPDAKLSTKALDLSSLASVAALGDQLNSEGRPIDILINNAGVMTPPERDTTADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 GSNHLGHFALTAH+LPLLRAAQ ARVVSLSSLAARRGRIHFDDLQFE+SYA MTAYGQSK Sbjct 121 GSNHLGHFALTAHVLPLLRAAQGARVVSLSSLAARRGRIHFDDLQFEKSYAAMTAYGQSK 180 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LAVLMFARELDRRSRAAGWG++SNAAHPGLTKTNLQI+GPSHGR+KPALM+R Y TSWRF Sbjct 181 LAVLMFARELDRRSRAAGWGVMSNAAHPGLTKTNLQISGPSHGREKPALMQRFYTTSWRF 240 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 APFLWQEIE+GILPALYAA TPQA+GGAFYGPRG YE AGGGVR AKVPA A NDAD +R Sbjct 241 APFLWQEIEDGILPALYAAVTPQAEGGAFYGPRGFYEAAGGGVRAAKVPARAGNDADCQR 300 Query 301 LWEVSEQLTGVSYPKS 316 LWEVSE+LTGV YP S Sbjct 301 LWEVSERLTGVGYPTS 316 >gi|240170101|ref|ZP_04748760.1| short chain dehydrogenase [Mycobacterium kansasii ATCC 12478] Length=317 Score = 565 bits (1455), Expect = 4e-159, Method: Compositional matrix adjust. Identities = 274/314 (88%), Positives = 295/314 (94%), Gaps = 0/314 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 MA DL+A VPDLSGKLA++TGANSGLGFGLARRLSA+GA+V+MAIRNRAKGEAA+E+IRT Sbjct 1 MANDLIAAVPDLSGKLAVVTGANSGLGFGLARRLSASGAEVVMAIRNRAKGEAAIEQIRT 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 AVPDAKLTIKALDLSSLASVAALGEQL ++GRPID+LINNAGVMTPPER TTADGFELQF Sbjct 61 AVPDAKLTIKALDLSSLASVAALGEQLNSEGRPIDILINNAGVMTPPERDTTADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 GSNHLGHFALTAH+LPLLRA ARVVSLSSLAARRGRIHFDDLQFE+SYAPMTAYGQSK Sbjct 121 GSNHLGHFALTAHVLPLLRATPAARVVSLSSLAARRGRIHFDDLQFEKSYAPMTAYGQSK 180 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LAVLMFARELDRRSR AGWGI SNAAHPGLTKTNLQI+GPSHGR+KPALM+RLY+ SWR Sbjct 181 LAVLMFARELDRRSREAGWGIKSNAAHPGLTKTNLQISGPSHGREKPALMQRLYQASWRL 240 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 PF WQEI+EGILPALYAAATPQA+GGAFYGPRG YE AGGGV EAKVPA ARNDAD +R Sbjct 241 TPFFWQEIDEGILPALYAAATPQAEGGAFYGPRGFYEAAGGGVTEAKVPARARNDADCRR 300 Query 301 LWEVSEQLTGVSYP 314 LWEVSE+LTGV YP Sbjct 301 LWEVSERLTGVRYP 314 >gi|296166151|ref|ZP_06848596.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898560|gb|EFG78121.1| short-chain dehydrogenase/reductase family oxidoreductase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=318 Score = 501 bits (1289), Expect = 7e-140, Method: Compositional matrix adjust. Identities = 268/317 (85%), Positives = 290/317 (92%), Gaps = 1/317 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 MA DLVATVPDLSGKLAI+TGANSGLGFGLARRL+AAGADV+MAIRNRAKGE A+ +IR Sbjct 1 MANDLVATVPDLSGKLAIVTGANSGLGFGLARRLAAAGADVVMAIRNRAKGEQAIADIRK 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 VPDAKLTIK+LDLSSLA+VAALGEQL A+GRP+D+LINNAGVMTPPER TT DGFELQF Sbjct 61 TVPDAKLTIKSLDLSSLAAVAALGEQLNAEGRPVDILINNAGVMTPPERDTTVDGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARR-GRIHFDDLQFERSYAPMTAYGQS 179 GSNHLGHFALT HLLPLLRAA ARVVSLSSLAAR+ G+IHFDD QFE+SYA M+AYGQS Sbjct 121 GSNHLGHFALTGHLLPLLRAAGNARVVSLSSLAARQSGKIHFDDPQFEKSYAAMSAYGQS 180 Query 180 KLAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWR 239 KLAVLMFA ELDRRSRAA WGI+SNAAHPGLTKTNLQIAGPSHGRDKP+LMERLYK SWR Sbjct 181 KLAVLMFALELDRRSRAARWGIVSNAAHPGLTKTNLQIAGPSHGRDKPSLMERLYKASWR 240 Query 240 FAPFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSK 299 F PF WQEI+EGILPALYAAA P A GGAFYGPRG YE AGGGVR AKVPA ARN+AD + Sbjct 241 FTPFFWQEIDEGILPALYAAAAPHAQGGAFYGPRGFYEAAGGGVRPAKVPARARNEADCQ 300 Query 300 RLWEVSEQLTGVSYPKS 316 RLWE+SE+LTGVSYPK+ Sbjct 301 RLWELSERLTGVSYPKA 317 >gi|254551308|ref|ZP_05141755.1| short chain dehydrogenase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=249 Score = 499 bits (1286), Expect = 2e-139, Method: Compositional matrix adjust. Identities = 249/249 (100%), Positives = 249/249 (100%), Gaps = 0/249 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT Sbjct 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF Sbjct 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK Sbjct 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF Sbjct 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 Query 241 APFLWQEIE 249 APFLWQEIE Sbjct 241 APFLWQEIE 249 >gi|254818826|ref|ZP_05223827.1| short chain dehydrogenase [Mycobacterium intracellulare ATCC 13950] Length=319 Score = 413 bits (1061), Expect = 2e-113, Method: Compositional matrix adjust. Identities = 200/311 (65%), Positives = 248/311 (80%), Gaps = 1/311 (0%) Query 4 DLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVP 63 DL +VPDL G+ A++TGANSGLGFGLA+RL+AAGADV+MA+R+R KGE AV +IR P Sbjct 5 DLALSVPDLRGRFAVVTGANSGLGFGLAKRLAAAGADVVMAVRDRVKGERAVADIRRDAP 64 Query 64 DAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSN 123 AKLTI LDLSSL SVAALGEQL A+GRPID+LINNAG+MTPP+R T DGFELQFG+N Sbjct 65 QAKLTIGQLDLSSLESVAALGEQLTAEGRPIDVLINNAGIMTPPQRQQTRDGFELQFGTN 124 Query 124 HLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAV 183 HLGHFALT LL LLRAA ARVV++SSLAA +G++ F D+ ++ Y PM +YG +KLA Sbjct 125 HLGHFALTGRLLSLLRAAGSARVVTVSSLAATQGKLDFGDVNAQQGYKPMHSYGVAKLAQ 184 Query 184 LMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPF 243 LMFA ELDRRSR GWG++SNAAHPGLTKTNL ++G S+GR KP L RL + +WR PF Sbjct 185 LMFAVELDRRSRRGGWGLMSNAAHPGLTKTNL-LSGASYGRAKPTLQARLTQLTWRVMPF 243 Query 244 LWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWE 303 +W +++EGI P LYAA +P A G +YGPRG YE GGV A+VP AR++AD ++LW+ Sbjct 244 MWLDVDEGIKPTLYAAVSPDAQGAKYYGPRGFYETVRGGVTFARVPRLARSEADMRQLWQ 303 Query 304 VSEQLTGVSYP 314 +SE+L+GV+YP Sbjct 304 LSEELSGVTYP 314 >gi|41407566|ref|NP_960402.1| short chain dehydrogenase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395919|gb|AAS03785.1| hypothetical protein MAP_1468c [Mycobacterium avium subsp. paratuberculosis K-10] gi|336457621|gb|EGO36625.1| dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein [Mycobacterium avium subsp. paratuberculosis S397] Length=315 Score = 394 bits (1013), Expect = 9e-108, Method: Compositional matrix adjust. Identities = 194/311 (63%), Positives = 239/311 (77%), Gaps = 1/311 (0%) Query 4 DLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVP 63 +L +PDL GK A++TGANSGLGFGLA+RL+AAGA+V++A+R+ AKG+ AV IR VP Sbjct 5 NLTLEIPDLRGKFAVVTGANSGLGFGLAKRLAAAGAEVVLAVRDPAKGDQAVAAIRREVP 64 Query 64 DAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSN 123 AKLTI+ LDLSSL SVAALGEQL A+GRPID+LINNAGVM PP R T+DGFELQFG+N Sbjct 65 QAKLTIRQLDLSSLRSVAALGEQLTAEGRPIDILINNAGVMAPPRRQQTSDGFELQFGTN 124 Query 124 HLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAV 183 HLGHFALT LL LLRAA ARVV++SS+AA + ++ F D+ E Y PM +YG +KLA Sbjct 125 HLGHFALTGRLLALLRAADSARVVTVSSIAATQRKLDFADVNAEHGYQPMYSYGVAKLAQ 184 Query 184 LMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPF 243 LMFA ELDRRSR GWG++SNAAHPGL KTNL ++G S+GR P L RL + +WR PF Sbjct 185 LMFAVELDRRSRLGGWGLMSNAAHPGLAKTNL-LSGASYGRSAPTLQARLTRLTWRLLPF 243 Query 244 LWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWE 303 +W +I+E + P LYAA +P A G +YGPRG YE A GGV A+VP AR++ + RLW Sbjct 244 MWLDIDEAVKPTLYAAVSPDAQGARYYGPRGFYETARGGVTFARVPPLARSEPEMARLWR 303 Query 304 VSEQLTGVSYP 314 +SEQL+GV YP Sbjct 304 LSEQLSGVDYP 314 >gi|118466655|ref|YP_882155.1| short chain dehydrogenase [Mycobacterium avium 104] gi|118167942|gb|ABK68839.1| short chain dehydrogenase [Mycobacterium avium 104] Length=314 Score = 392 bits (1007), Expect = 4e-107, Method: Compositional matrix adjust. Identities = 194/314 (62%), Positives = 239/314 (77%), Gaps = 1/314 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 M +L +PDL GK A++TGANSGLGFGLA+RL+AAGA+V++A+R+ AKG+ AV IR Sbjct 1 MKPNLTLEIPDLRGKFAVVTGANSGLGFGLAKRLAAAGAEVVLAVRDPAKGDQAVAAIRR 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 AVP AKLTI+ LDLSSL SVAALGEQL A+GRPID+LINNAGVM PP R T+DGFELQF Sbjct 61 AVPQAKLTIRQLDLSSLRSVAALGEQLTAEGRPIDILINNAGVMAPPRRQQTSDGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 G+NHLGHFALT LL LLRAA ARVV++SS+AA + ++ F D+ E Y PM +YG +K Sbjct 121 GTNHLGHFALTGRLLALLRAADSARVVTVSSIAATQRKLDFADVNAEHGYQPMYSYGVAK 180 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LA LMFA ELD RSR GWG++SNAAHPGL KTNL ++G S+G P L RL + +WR Sbjct 181 LAQLMFAVELDWRSRLGGWGLMSNAAHPGLAKTNL-LSGASYGSSAPTLQARLTRLTWRL 239 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 PF+W +I+E + P LYAA +P A G +YGPRG YE A GGV A+VP AR++ + R Sbjct 240 LPFMWLDIDEAVKPTLYAAVSPDAQGARYYGPRGFYETARGGVTFARVPPLARSEPEMAR 299 Query 301 LWEVSEQLTGVSYP 314 LW +SEQL+GV YP Sbjct 300 LWRLSEQLSGVDYP 313 >gi|342861353|ref|ZP_08718001.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] gi|342131253|gb|EGT84534.1| short chain dehydrogenase [Mycobacterium colombiense CECT 3035] Length=315 Score = 391 bits (1004), Expect = 8e-107, Method: Compositional matrix adjust. Identities = 204/311 (66%), Positives = 247/311 (80%), Gaps = 1/311 (0%) Query 4 DLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVP 63 DL VP L G+ A++TGANSGLGFGLA+RLSAAGADV++A+R+RAKGE A+ EIR AVP Sbjct 5 DLALDVPALRGRFAVVTGANSGLGFGLAKRLSAAGADVVLAVRDRAKGERAIAEIRRAVP 64 Query 64 DAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSN 123 +AKL I+ LDLSSL+S+AALGE+L A+GRPID+LINNAGVMTPPER T DGFELQFG+N Sbjct 65 EAKLGIRQLDLSSLSSIAALGEELTAEGRPIDILINNAGVMTPPERQQTGDGFELQFGTN 124 Query 124 HLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAV 183 +LGHFALT LL LLRAA ARVV++SS+AA + + F D+ +R Y PM AYG +KLA Sbjct 125 YLGHFALTGRLLGLLRAAAAARVVTVSSIAATQRDLDFGDVNAQRGYKPMHAYGVAKLAQ 184 Query 184 LMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPF 243 LMFA ELDRRSRA GWG++SNAAHPGLTKTNL ++G S+GR P L RL + +WR PF Sbjct 185 LMFAVELDRRSRAGGWGLMSNAAHPGLTKTNL-LSGASYGRTTPTLQARLTRLTWRLLPF 243 Query 244 LWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWE 303 +W I+EGI P LYAA +P A GGA+YGPRG YE GGV A VP AR++ D ++LW+ Sbjct 244 MWLNIDEGIKPTLYAAVSPDAQGGAYYGPRGFYETVRGGVTFAAVPQLARSEPDMRQLWQ 303 Query 304 VSEQLTGVSYP 314 +SEQLTGV YP Sbjct 304 LSEQLTGVRYP 314 >gi|317509010|ref|ZP_07966641.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974] gi|316252665|gb|EFV12104.1| short chain dehydrogenase [Segniliparus rugosus ATCC BAA-974] Length=316 Score = 384 bits (987), Expect = 9e-105, Method: Compositional matrix adjust. Identities = 194/311 (63%), Positives = 240/311 (78%), Gaps = 4/311 (1%) Query 3 KDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAV 62 + L VPDL+G+LA++TGANSGLGFG+A+RL+ AGA+V++A+RN+ KGE A I+ Sbjct 4 RSLNLAVPDLTGRLAVVTGANSGLGFGIAKRLAEAGAEVLLAVRNQQKGEDAAARIKAEN 63 Query 63 PDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGS 122 P A++ ++ LDL+SLASVAALGEQL A+ RPI +L+NNAGVMTPP R T DGFELQFGS Sbjct 64 PKARVGLRRLDLASLASVAALGEQLNAEARPIHILVNNAGVMTPPRREVTEDGFELQFGS 123 Query 123 NHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLA 182 N+LGHFALT HLLPLLRAA+ RV ++SS AAR G++ FDDLQ ER Y + AYG SKLA Sbjct 124 NYLGHFALTGHLLPLLRAAENPRVTTMSSDAARYGKLDFDDLQSERRYRSLAAYGASKLA 183 Query 183 VLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAP 242 L+FARELDRRSRA GWGI+SNAAHPG TKTNLQ AGP++G DKP L R+ S P Sbjct 184 DLVFARELDRRSRAEGWGIVSNAAHPGATKTNLQTAGPNYGSDKPNLFGRM---SQLLTP 240 Query 243 FLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLW 302 L+QEI+EG ALYAA +P+A GGA+YGP G + GGG + A+ P A ++A ++RLW Sbjct 241 -LFQEIDEGAQAALYAATSPEATGGAYYGPVGFMGMIGGGAKLAREPKQANDEAAARRLW 299 Query 303 EVSEQLTGVSY 313 VSEQLTGV Y Sbjct 300 TVSEQLTGVRY 310 >gi|254775441|ref|ZP_05216957.1| short chain dehydrogenase [Mycobacterium avium subsp. avium ATCC 25291] Length=315 Score = 367 bits (941), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 192/311 (62%), Positives = 237/311 (77%), Gaps = 1/311 (0%) Query 4 DLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVP 63 +L +PDL GK A++TGANSGLGFGLA+RL+AAGA+V++A+R+ AKG+ AV IR VP Sbjct 5 NLTLEIPDLRGKFAVVTGANSGLGFGLAKRLAAAGAEVVLAVRDPAKGDQAVAAIRREVP 64 Query 64 DAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSN 123 AKLTI+ LDLSSL SVAALGEQL A+GRPID+LINNAGVM PP R T+DGFELQFG+N Sbjct 65 QAKLTIRQLDLSSLRSVAALGEQLTAEGRPIDILINNAGVMAPPRRQQTSDGFELQFGTN 124 Query 124 HLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAV 183 HLGHFALT LL LLRAA ARVV++SS+AA + ++ F D+ E Y PM +YG +KLA Sbjct 125 HLGHFALTGLLLALLRAADSARVVTVSSIAATQRKLDFADVNAEHGYQPMYSYGVAKLAQ 184 Query 184 LMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPF 243 LMFA ELD RSR GWG++SNAAHPGL KTNL ++G S+G P L RL + +WR PF Sbjct 185 LMFAVELDWRSRLGGWGLMSNAAHPGLAKTNL-LSGASYGSSAPTLQARLTRLTWRLLPF 243 Query 244 LWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWE 303 +W +I+E + P LYAA +P A G +YGPRG YE A GGV A+VP AR++ + RLW Sbjct 244 MWLDIDEAVKPTLYAAVSPDAQGARYYGPRGFYETARGGVTFARVPPLARSEPEMARLWR 303 Query 304 VSEQLTGVSYP 314 +SEQL+GV YP Sbjct 304 LSEQLSGVDYP 314 >gi|289750860|ref|ZP_06510238.1| oxidoreductase [Mycobacterium tuberculosis T92] gi|289691447|gb|EFD58876.1| oxidoreductase [Mycobacterium tuberculosis T92] Length=185 Score = 365 bits (938), Expect = 4e-99, Method: Compositional matrix adjust. Identities = 185/185 (100%), Positives = 185/185 (100%), Gaps = 0/185 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT Sbjct 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF Sbjct 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK Sbjct 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 Query 181 LAVLM 185 LAVLM Sbjct 181 LAVLM 185 >gi|158315370|ref|YP_001507878.1| short chain dehydrogenase [Frankia sp. EAN1pec] gi|158110775|gb|ABW12972.1| short-chain dehydrogenase/reductase SDR [Frankia sp. EAN1pec] Length=308 Score = 323 bits (828), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 169/303 (56%), Positives = 225/303 (75%), Gaps = 3/303 (0%) Query 11 DLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKLTIK 70 DL+G+LA++TGA+SGLG GLA RL+AAGA V++ +R+ AKGEAA+ IR P A ++++ Sbjct 6 DLTGRLAVVTGASSGLGLGLATRLAAAGAKVLLPVRDEAKGEAALSHIRAEAPGADVSLR 65 Query 71 ALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHFAL 130 LDL+SL SV ALG+ L A+GRPI +LINNAG+MTP R TTADG ELQFG+NH+GHFAL Sbjct 66 ELDLASLKSVEALGDTLNAEGRPIHILINNAGLMTPATRHTTADGLELQFGTNHIGHFAL 125 Query 131 TAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFAREL 190 T LLPLL A ARV +++S AAR +++++DLQ +++YAP+ AY QSKLA L+FA EL Sbjct 126 TGWLLPLLNAGH-ARVTTMTSSAARHAKLNWEDLQSDQAYAPIRAYNQSKLANLLFALEL 184 Query 191 DRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLWQEIEE 250 DRRSRA GWGI+SNAAHPG T T L AGP+ GR+K + +E K R+ L Q ++ Sbjct 185 DRRSRAGGWGIVSNAAHPGTTLTGLYAAGPNLGREKSSPIEAAMKRLARWG-VLVQGVDR 243 Query 251 GILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQLTG 310 G+LPALYAA +P A+GG FYGP G + GG E ++ AR++ + RLW+VS++L G Sbjct 244 GLLPALYAATSPDAEGGHFYGPDGFGQFTGGPA-ELEIYRPARDEDAATRLWDVSQRLAG 302 Query 311 VSY 313 V + Sbjct 303 VEF 305 >gi|229822648|ref|YP_002884174.1| short chain dehydrogenase [Beutenbergia cavernae DSM 12333] gi|229568561|gb|ACQ82412.1| short-chain dehydrogenase/reductase SDR [Beutenbergia cavernae DSM 12333] Length=312 Score = 322 bits (825), Expect = 5e-86, Method: Compositional matrix adjust. Identities = 178/307 (58%), Positives = 220/307 (72%), Gaps = 5/307 (1%) Query 8 TVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKL 67 +VPDLSG+ A++TGA+ G+G +A RL+ AGA+V+M +RN KGEAA+ IR P AKL Sbjct 9 SVPDLSGRRAVVTGASDGVGLAIATRLAGAGAEVVMPVRNARKGEAALTRIRERHPAAKL 68 Query 68 TIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGH 127 ++ LDLSSLASVAALGE L ADG PI LL+NNAGVMTPPER TTADGFELQFG+NHLGH Sbjct 69 VLRELDLSSLASVAALGETLRADGAPIHLLVNNAGVMTPPERQTTADGFELQFGTNHLGH 128 Query 128 FALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFA 187 ALTAHLLPLL+A RARV S +S+AARRG I++DDL +ERSY M +Y QSK+AV +F Sbjct 129 VALTAHLLPLLKAG-RARVTSQASIAARRGAINWDDLNWERSYDGMRSYRQSKIAVGLFG 187 Query 188 RELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFA-PFLWQ 246 EL RRSRAAGWGI SN +HPG+ T+L A P GR + RL + W A + Sbjct 188 LELSRRSRAAGWGITSNISHPGVAPTSLLAARPEVGRGQDTRDVRLIR--WLSARGLIVG 245 Query 247 EIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSE 306 +E LPAL AA +P+A G FYGP+ + GG ++ A R DAD+ RLW VSE Sbjct 246 TVESAKLPALLAATSPEAKDGGFYGPQWPGNM-GGPPGSQRLWAPLRRDADAARLWSVSE 304 Query 307 QLTGVSY 313 +LTGV++ Sbjct 305 ELTGVTF 311 >gi|84495943|ref|ZP_00994797.1| short chain dehydrogenase [Janibacter sp. HTCC2649] gi|84382711|gb|EAP98592.1| short chain dehydrogenase [Janibacter sp. HTCC2649] Length=314 Score = 311 bits (796), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 176/309 (57%), Positives = 219/309 (71%), Gaps = 3/309 (0%) Query 8 TVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKL 67 T+PDLSGK A++TGA+ G+G +A RL+AAGA+VIM +RNR+KG+AA+ +I A P A L Sbjct 9 TLPDLSGKRAVVTGASDGMGLRIAARLAAAGAEVIMPVRNRSKGDAAITQITQANPSANL 68 Query 68 TIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGH 127 +++ LDLSSLASVAALGE L +GRPI LLINNAGVMTPPER TTADGFELQFGSNHLGH Sbjct 69 SLRDLDLSSLASVAALGETLGEEGRPIHLLINNAGVMTPPERQTTADGFELQFGSNHLGH 128 Query 128 FALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFA 187 FAL AHLLPLLR Q ARV S S+AA RG +++DDL +E+SY M AY QSK+A +F Sbjct 129 FALVAHLLPLLREGQ-ARVTSQISIAANRGAMNWDDLNWEKSYDGMKAYSQSKIAFGLFG 187 Query 188 RELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLWQE 247 ELDRRS+A GWGI SN +HPG+ TNL A P GR K + R+ + + L Sbjct 188 LELDRRSKAQGWGISSNLSHPGVAPTNLLAARPELGRAKDTVGRRIVR-ALSEKGVLLGT 246 Query 248 IEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQ 307 ++ LPAL AA PQA G YGPRG + GG E + + + AD++R WEVSE+ Sbjct 247 VDSAALPALMAATDPQATSGVLYGPRGLGHL-GGAPAEQSMYSRLVSTADAQRNWEVSER 305 Query 308 LTGVSYPKS 316 LTG +P + Sbjct 306 LTGTYFPTA 314 >gi|289758388|ref|ZP_06517766.1| hypothetical protein TBEG_01067 [Mycobacterium tuberculosis T85] gi|289713952|gb|EFD77964.1| hypothetical protein TBEG_01067 [Mycobacterium tuberculosis T85] Length=154 Score = 310 bits (795), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 150/150 (100%), Positives = 150/150 (100%), Gaps = 0/150 (0%) Query 168 RSYAPMTAYGQSKLAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKP 227 RSYAPMTAYGQSKLAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKP Sbjct 5 RSYAPMTAYGQSKLAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKP 64 Query 228 ALMERLYKTSWRFAPFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAK 287 ALMERLYKTSWRFAPFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAK Sbjct 65 ALMERLYKTSWRFAPFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAK 124 Query 288 VPAAARNDADSKRLWEVSEQLTGVSYPKSR 317 VPAAARNDADSKRLWEVSEQLTGVSYPKSR Sbjct 125 VPAAARNDADSKRLWEVSEQLTGVSYPKSR 154 >gi|291454342|ref|ZP_06593732.1| short chain dehydrogenase [Streptomyces albus J1074] gi|291357291|gb|EFE84193.1| short chain dehydrogenase [Streptomyces albus J1074] Length=314 Score = 308 bits (789), Expect = 7e-82, Method: Compositional matrix adjust. Identities = 167/312 (54%), Positives = 217/312 (70%), Gaps = 3/312 (0%) Query 3 KDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAV 62 K + T+PDLSG+ A++TGA+ GLG GLA RL+ AGA+V++ +RN+ KG AA+EEIR Sbjct 4 KPVDLTLPDLSGRRAVVTGASDGLGLGLAARLAQAGAEVVLPVRNQEKGRAALEEIRRGA 63 Query 63 PDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGS 122 P A+++++ LDLSSLASVAALGE L + RP+ LL+NNAGVMTPP+R TTADGFELQFG+ Sbjct 64 PGAEVSLRELDLSSLASVAALGEALRTEDRPVHLLVNNAGVMTPPQRRTTADGFELQFGT 123 Query 123 NHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLA 182 NHLGHFALTAHLLPLLRA RARV S S+AA R I+++D +E SY M AY SK+A Sbjct 124 NHLGHFALTAHLLPLLRAG-RARVTSQISVAADRNAINWEDPNWESSYNGMKAYSHSKIA 182 Query 183 VLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAP 242 +F EL+RR+RA WG+ SN +HPG+ T+L A P GR K R K + Sbjct 183 FGLFGLELERRARAHDWGLTSNLSHPGVAPTSLLAARPEVGRAKDTTGRRFIK-ALSARG 241 Query 243 FLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLW 302 L +E PALYAA P+A GG YGP G + GG E K+ + R+ D++R+W Sbjct 242 ILLGTVESAKFPALYAATAPEAGGGRLYGPSGPGHL-GGPPAEQKLYSRLRSIEDARRVW 300 Query 303 EVSEQLTGVSYP 314 +SE+LTGV++P Sbjct 301 HLSEELTGVTFP 312 >gi|297561321|ref|YP_003680295.1| short-chain dehydrogenase/reductase SDR [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296845769|gb|ADH67789.1| short-chain dehydrogenase/reductase SDR [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=314 Score = 308 bits (789), Expect = 7e-82, Method: Compositional matrix adjust. Identities = 168/307 (55%), Positives = 215/307 (71%), Gaps = 3/307 (0%) Query 8 TVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKL 67 TVPDL+G+ A++TGA+ G+G G+A RL+AAGA+VIM +RN KGE A+ IR + PDA++ Sbjct 9 TVPDLTGRRALVTGASDGMGLGMAMRLAAAGAEVIMPVRNPRKGEDAIARIRRSRPDARV 68 Query 68 TIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGH 127 +++ LDLSSLASVAALG+ L +G PI +LINNAGVMTPP+R TTADGFE+QFG+NHLGH Sbjct 69 SLRDLDLSSLASVAALGDTLREEGLPIHILINNAGVMTPPDRQTTADGFEVQFGTNHLGH 128 Query 128 FALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFA 187 FAL LLPLLRA RARV S S+AARRG +++DDL +ERSY M AY QSK+A +F Sbjct 129 FALVGRLLPLLRAG-RARVTSQISVAARRGAVNWDDLNWERSYDGMRAYSQSKIAFGLFG 187 Query 188 RELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLWQE 247 EL+RRSRA GWGI SN +HPG+ T+L A P GRD+ L RL + + L Sbjct 188 LELERRSRAHGWGITSNLSHPGVAPTSLLAARPELGRDRDTLGVRLIR-ALSARGILLGT 246 Query 248 IEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQ 307 +E LPAL AA P A+ G Y P G + GG E ++ R +++R+W VSEQ Sbjct 247 VESAKLPALMAATDPAAEPGMLYSPSGPGNL-GGPPAEQRLYTPLRGADEAERVWRVSEQ 305 Query 308 LTGVSYP 314 LTG + P Sbjct 306 LTGTAIP 312 >gi|256378491|ref|YP_003102151.1| short-chain dehydrogenase/reductase SDR [Actinosynnema mirum DSM 43827] gi|255922794|gb|ACU38305.1| short-chain dehydrogenase/reductase SDR [Actinosynnema mirum DSM 43827] Length=303 Score = 307 bits (787), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 168/305 (56%), Positives = 216/305 (71%), Gaps = 15/305 (4%) Query 12 LSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKLTIKA 71 L+GKLA++TGA+ G+G GLARRL+A GA+V++ +R+ AKG AA+E+I A + + Sbjct 6 LTGKLAVVTGASDGIGLGLARRLAALGAEVVIPVRDAAKGRAALEKIGGAS-----STRV 60 Query 72 LDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHFALT 131 LDL+SLASVA L ++L A+GRPIDLL+NNA VMTPP R TTADGFELQFG+N+LGHFAL Sbjct 61 LDLASLASVADLADRLTAEGRPIDLLVNNAAVMTPPTRHTTADGFELQFGTNYLGHFALV 120 Query 132 AHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFARELD 191 A LLPLL AA RARV + SL + GR+++DDLQ ER+Y+P AY QSKLA +FA ELD Sbjct 121 ARLLPLLVAA-RARVTTQVSLGSMAGRVNWDDLQSERAYSPWGAYNQSKLATKLFALELD 179 Query 192 RRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPAL---MERLYKTSWRFAPFLWQEI 248 RRSRA GWGI SN AHPG T TNLQ AGP+ G + A L + W Q + Sbjct 180 RRSRAHGWGITSNTAHPGFTATNLQKAGPTMGGARSAFDAPFRVLSRLGWPV-----QTV 234 Query 249 EEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQL 308 E G+ PAL+AA +P A GG FYGPRG + + G E +V AR+++D+ RLW++S L Sbjct 235 EGGLRPALHAATSPDALGGRFYGPRGLFHLTGAATEE-RVYRRARSESDAARLWDLSLDL 293 Query 309 TGVSY 313 V++ Sbjct 294 ADVAF 298 >gi|126347794|emb|CAJ89514.1| putative oxidoreductase [Streptomyces ambofaciens ATCC 23877] Length=313 Score = 303 bits (777), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 167/309 (55%), Positives = 214/309 (70%), Gaps = 3/309 (0%) Query 3 KDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAV 62 +D +VPDL+GK A++TGA+ G+G G+A RL+AAGA+V+M +RN KGE AV IR Sbjct 4 QDTDISVPDLTGKRAVVTGASDGIGLGIATRLAAAGAEVVMPVRNPRKGEGAVARIRQGA 63 Query 63 PDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGS 122 P A ++++ALDLSSLASV ALG+ L+ +GRPI LL+NNAGVMTPP+R TTADGFELQFG+ Sbjct 64 PHANVSLRALDLSSLASVTALGKALLDEGRPIHLLVNNAGVMTPPDRQTTADGFELQFGT 123 Query 123 NHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLA 182 NHLGHFAL HLLPLLRA RARV S S+AA R I++DDL ++RSY M AY QSK+A Sbjct 124 NHLGHFALVHHLLPLLRAG-RARVTSQISVAANRNAINWDDLGWQRSYNGMRAYSQSKIA 182 Query 183 VLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAP 242 + +F ELDRRS AAGWGI SN +HPG+ T+L A P GR + L RL + + Sbjct 183 LGLFGLELDRRSEAAGWGITSNLSHPGIAPTSLLAARPEVGRTEDTLGVRLIR-ALSTRG 241 Query 243 FLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLW 302 L + LPAL AA +PQA GG FY GG E K+ + R+ +++R+W Sbjct 242 ILVGTVHTAQLPALLAATSPQAVGGGFY-GPKGPGHMGGPPGEQKLYSRLRDTGEAQRIW 300 Query 303 EVSEQLTGV 311 +SE+L GV Sbjct 301 RISEELAGV 309 >gi|294993497|ref|ZP_06799188.1| short chain dehydrogenase [Mycobacterium tuberculosis 210] gi|326903877|gb|EGE50810.1| hypothetical protein TBPG_01763 [Mycobacterium tuberculosis W-148] gi|339295178|gb|AEJ47289.1| short chain dehydrogenase [Mycobacterium tuberculosis CCDC5079] gi|339298798|gb|AEJ50908.1| short chain dehydrogenase [Mycobacterium tuberculosis CCDC5180] Length=145 Score = 300 bits (768), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 145/145 (100%), Positives = 145/145 (100%), Gaps = 0/145 (0%) Query 173 MTAYGQSKLAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMER 232 MTAYGQSKLAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMER Sbjct 1 MTAYGQSKLAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMER 60 Query 233 LYKTSWRFAPFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAA 292 LYKTSWRFAPFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAA Sbjct 61 LYKTSWRFAPFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAA 120 Query 293 RNDADSKRLWEVSEQLTGVSYPKSR 317 RNDADSKRLWEVSEQLTGVSYPKSR Sbjct 121 RNDADSKRLWEVSEQLTGVSYPKSR 145 >gi|120402076|ref|YP_951905.1| short chain dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119954894|gb|ABM11899.1| short-chain dehydrogenase/reductase SDR [Mycobacterium vanbaalenii PYR-1] Length=320 Score = 300 bits (767), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 179/319 (57%), Positives = 219/319 (69%), Gaps = 7/319 (2%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 M + DL GKLA+ITG + G+GFGLA RL+AAGA+VI+ +RN KG A + IRT Sbjct 4 MTRKATVDARDLHGKLAVITGGSDGIGFGLAGRLAAAGAEVILPVRNADKGRRAADAIRT 63 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 PDA+++ + +DLSSL SVA L ++L+ +GRPI LLINNAGVM PP R TT DGFELQ+ Sbjct 64 TTPDARISTRPMDLSSLQSVADLADELLREGRPIHLLINNAGVMNPPSRQTTVDGFELQW 123 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 G+NHLGHFALTA LLPLL A ARV + SS++A R I++DDL FE+SYA AY QSK Sbjct 124 GTNHLGHFALTARLLPLLTAGA-ARVTTQSSISAARHAINWDDLNFEKSYAVGKAYSQSK 182 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 +A LMF ELDRRSR AGWGI SN AHPG+T TNL A P GRD L RL + R Sbjct 183 IANLMFGLELDRRSRHAGWGITSNVAHPGVTATNLLAAQPHMGRDGDTLSVRLIR---RL 239 Query 241 APF--LWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADS 298 A L Q +++G+LPALYAA P A+GG FYGP G ++ G E +V AR+ AD+ Sbjct 240 AGLGILTQTVDQGLLPALYAATHPDAEGGKFYGPSG-FQHLSGAPAEQQVYGPARDAADA 298 Query 299 KRLWEVSEQLTGVSYPKSR 317 RLW VSEQL G + R Sbjct 299 ARLWRVSEQLAGAQFALPR 317 >gi|169630153|ref|YP_001703802.1| short chain dehydrogenase [Mycobacterium abscessus ATCC 19977] gi|169242120|emb|CAM63148.1| Putative short-chain dehydrogenase/reductase [Mycobacterium abscessus] Length=312 Score = 296 bits (759), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 164/306 (54%), Positives = 204/306 (67%), Gaps = 5/306 (1%) Query 9 VPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKLT 68 +PDLSG+ A++TGA+ G+G +A +L+ AGADV M +RN KG+AAV IR P A LT Sbjct 10 IPDLSGQRAVVTGASDGIGLEIAMKLAGAGADVFMPVRNLRKGQAAVSRIRALHPRAHLT 69 Query 69 IKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHF 128 + LDLSSL S+A LGE+L A+G PI LLINNAGVMTPPER TTADGFELQFG+NHLGHF Sbjct 70 LAELDLSSLVSIADLGEKLCAEGTPIHLLINNAGVMTPPERQTTADGFELQFGTNHLGHF 129 Query 129 ALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFAR 188 ALT HLLPLLRA RARV S +S+AAR G I++DDL +ER Y M AY QSK+A +F Sbjct 130 ALTGHLLPLLRAG-RARVTSHTSIAARSGEINWDDLNWERGYDGMRAYRQSKIACGLFGL 188 Query 189 ELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFA-PFLWQE 247 EL R S AGWGI SN AHPG+ T+L A P GR K R+ + W A + Sbjct 189 ELSRLSNTAGWGITSNIAHPGVAPTSLLAARPEVGRTKDTTEVRMIR--WLSARGLIVGT 246 Query 248 IEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQ 307 + LPAL AA P+A G FYGPR G + K+ + ++ RLW+ S++ Sbjct 247 VASATLPALMAAVAPEATDGGFYGPRWPGSAGGPPGPQ-KLWKPLHSIRNASRLWQASQE 305 Query 308 LTGVSY 313 LTGV++ Sbjct 306 LTGVTF 311 >gi|329937548|ref|ZP_08287106.1| short chain dehydrogenase [Streptomyces griseoaurantiacus M045] gi|329303424|gb|EGG47311.1| short chain dehydrogenase [Streptomyces griseoaurantiacus M045] Length=312 Score = 296 bits (758), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 167/308 (55%), Positives = 219/308 (72%), Gaps = 3/308 (0%) Query 4 DLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVP 63 D+ TVPDLSG+ A++TGA+ G+G LA RL+AAGA+V++ +RN KGEAA+ IRT VP Sbjct 5 DIDITVPDLSGRRAVVTGASDGIGLVLATRLAAAGAEVLLPVRNPRKGEAALAAIRTEVP 64 Query 64 DAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSN 123 DA ++++ L+LSSL SV ALGE L+A+ RPI LL+NNAGVMTPPER TT DGFELQFG+N Sbjct 65 DADVSLRTLELSSLKSVTALGETLLAEDRPIHLLVNNAGVMTPPERQTTEDGFELQFGTN 124 Query 124 HLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAV 183 HLGHFAL A LLPLLRA RARV + S+AA + I+++DL +ERSY+ AY QSK+A Sbjct 125 HLGHFALVARLLPLLRAG-RARVTTQISVAANQYAINWEDLNWERSYSGGRAYSQSKIAA 183 Query 184 LMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPF 243 +F ELDRRS A GWGI SN +HPG+ T+L A P GR K + R+ + + Sbjct 184 GLFGLELDRRSAAGGWGITSNLSHPGIAPTSLLAARPELGRAKDTVGVRVIR-ALSARGI 242 Query 244 LWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWE 303 L + LPALYAA +P+A+GGAFYGP G + G VR+ K+ + + +++R+W Sbjct 243 LLGTVRTAQLPALYAATSPEAEGGAFYGPGGPGHLGGPPVRQ-KLYSRLHSTDEAERVWA 301 Query 304 VSEQLTGV 311 SE+LTGV Sbjct 302 RSEELTGV 309 >gi|296138432|ref|YP_003645675.1| short-chain dehydrogenase/reductase SDR [Tsukamurella paurometabola DSM 20162] gi|296026566|gb|ADG77336.1| short-chain dehydrogenase/reductase SDR [Tsukamurella paurometabola DSM 20162] Length=312 Score = 295 bits (754), Expect = 8e-78, Method: Compositional matrix adjust. Identities = 168/308 (55%), Positives = 212/308 (69%), Gaps = 10/308 (3%) Query 9 VPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKLT 68 +PDL+GK A++TG G+G G+A L+AAGA+V++ RN AK AA IR A PDA+++ Sbjct 10 LPDLTGKRAVVTGGTDGIGLGIAGHLAAAGAEVVLPARNPAKAAAAQAVIRDATPDARIS 69 Query 69 IKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHF 128 I++LDLSSLASV LG++L+ DGRPI LLINNAGVMTPP R TADGFELQFG+NHLGHF Sbjct 70 IESLDLSSLASVGELGQRLLTDGRPIHLLINNAGVMTPPTRQVTADGFELQFGTNHLGHF 129 Query 129 ALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFAR 188 AL AHLLPLLRA ARV S S+AA I++DDL +ERSY AY QSK+A +F Sbjct 130 ALVAHLLPLLRAGN-ARVTSQISIAANERSINWDDLNWERSYNGGGAYSQSKIAFGLFGL 188 Query 189 ELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAP---FLW 245 ELDRRSR GWGI SN AHPG+ T+L A P GRD L RL RFA + Sbjct 189 ELDRRSREHGWGISSNLAHPGVAPTSLLAARPEIGRDGDTLGVRLI----RFASARGLVV 244 Query 246 QEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVS 305 +E LPAL AA TP+A GG YGP+G + GG E + + R++ +++R+W+VS Sbjct 245 GTVESAKLPALMAATTPEA-GGKMYGPKGFMHL-GGPPAEQALYSRIRSEDEARRMWQVS 302 Query 306 EQLTGVSY 313 E+LTG ++ Sbjct 303 EELTGATF 310 >gi|152966532|ref|YP_001362316.1| short chain dehydrogenase [Kineococcus radiotolerans SRS30216] gi|151361049|gb|ABS04052.1| short-chain dehydrogenase/reductase SDR [Kineococcus radiotolerans SRS30216] Length=316 Score = 292 bits (748), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 165/310 (54%), Positives = 213/310 (69%), Gaps = 11/310 (3%) Query 8 TVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKL 67 ++PDLSG+ A++TGA+ G+GFG+ARRL+ AGA+V++ +RNR KGEAA+ IR P AK+ Sbjct 8 SLPDLSGRRALVTGASDGIGFGIARRLAGAGAEVLLPVRNRTKGEAALARIREQHPTAKV 67 Query 68 TIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGH 127 T+ LDLSSL+SVAALG++L A+G PI LLINNAGVMTPP+R TT DG ELQ G+NHLGH Sbjct 68 TLHDLDLSSLSSVAALGDELRAEGSPIHLLINNAGVMTPPQRQTTVDGLELQLGTNHLGH 127 Query 128 FALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFA 187 AL AHLLPLLRA RARV S S+AAR G +H++DL +E SY M AY SK+A+ +F Sbjct 128 VALVAHLLPLLRAG-RARVTSQISVAARSGAVHWEDLNWEDSYHGMRAYSSSKIALGLFG 186 Query 188 RELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKP----ALMERLYKTSWRFAPF 243 ELDRRSRA GWGI SN +HPG+ T+L A P R++ A++ RL + A Sbjct 187 LELDRRSRAEGWGITSNLSHPGVAPTSLLAARPELQRERNTPQIAVIRRLSR-----AGI 241 Query 244 LWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWE 303 L ++ LPAL+AA PQA GG YG GGG E + R+ ++ R+W Sbjct 242 LVGTVDSAQLPALHAATAPQAQGGRLYG-PTGPGNLGGGPGEQPLYRPLRDQTEADRVWT 300 Query 304 VSEQLTGVSY 313 VS+ L GVS+ Sbjct 301 VSQALAGVSF 310 >gi|326333015|ref|ZP_08199271.1| oxidoreductase, short-chain dehydrogenase/reductase family [Nocardioidaceae bacterium Broad-1] gi|325949209|gb|EGD41293.1| oxidoreductase, short-chain dehydrogenase/reductase family [Nocardioidaceae bacterium Broad-1] Length=314 Score = 291 bits (745), Expect = 9e-77, Method: Compositional matrix adjust. Identities = 168/308 (55%), Positives = 212/308 (69%), Gaps = 5/308 (1%) Query 8 TVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKL 67 T+PDLSG+ A++TGA+ G+G +A RL+AAGA+V+M +RN AKG+ A+ IR VP+A + Sbjct 9 TIPDLSGRRALVTGASDGMGLVMATRLAAAGAEVVMPVRNAAKGKKALATIREQVPEASV 68 Query 68 TIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGH 127 +++ LDLSSLASVAAL E L+ + +P ++INNAGVMTPPER TTADGFELQ G+NHLGH Sbjct 69 SLRDLDLSSLASVAALSEMLLGEDQPFHVMINNAGVMTPPERQTTADGFELQLGTNHLGH 128 Query 128 FALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFA 187 FAL A +LPLLRA Q ARV S S+AARRG I++DD +E+SY M AY QSK+AV +F Sbjct 129 FALVAKILPLLRAGQ-ARVTSQVSIAARRGAINWDDPNWEQSYNVMRAYSQSKVAVGLFG 187 Query 188 RELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFA-PFLWQ 246 ELDRRSRA GWGI SN +HPG+ TNL A P GR R+ + W A L Sbjct 188 LELDRRSRAGGWGITSNLSHPGVAPTNLLAARPEIGRTTDTFSVRMIR--WLSARGILLG 245 Query 247 EIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSE 306 E LPAL AA +P+A GG YGP G + GG E + + D+ RLWEVSE Sbjct 246 TPETAALPALLAATSPEATGGRMYGPSGPGNL-GGAPAEQPLYRPMVSAEDAARLWEVSE 304 Query 307 QLTGVSYP 314 +LT V+ P Sbjct 305 RLTRVALP 312 >gi|258654166|ref|YP_003203322.1| short chain dehydrogenase [Nakamurella multipartita DSM 44233] gi|258557391|gb|ACV80333.1| short-chain dehydrogenase/reductase SDR [Nakamurella multipartita DSM 44233] Length=313 Score = 291 bits (745), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 178/315 (57%), Positives = 217/315 (69%), Gaps = 3/315 (0%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 M K + TVPDLSG+ A++TGA+ GLG GLA RL+AAGA+VIM +RN+ KGEAA++ IR Sbjct 1 MTKTIDITVPDLSGRRAVVTGASDGLGVGLAGRLAAAGAEVIMPVRNQRKGEAAIDRIRR 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 + PDA ++++ LDLSSL SVA LG L + RPI LLINNAGVMTPPER TADGFELQF Sbjct 61 SAPDATVSLRELDLSSLDSVAELGRTLTQEDRPIHLLINNAGVMTPPERQNTADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 GSNHLGH AL AHLLPLLRA Q ARV S S+AA RG I++DDL +ERSY M AY QSK Sbjct 121 GSNHLGHVALVAHLLPLLRAGQ-ARVTSQVSVAAARGSINWDDLNWERSYDGMKAYRQSK 179 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 +A+ +F ELDRRSRAAGWGI SN AHPG+ TNL A P GR K L R+ + + Sbjct 180 IALGLFGLELDRRSRAAGWGISSNLAHPGVAPTNLLAARPEVGRAKDTLGVRVIR-ALSA 238 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 L + LPA+YAA +P A G YGP G + G E K+ R D + R Sbjct 239 RGLLVGTVASAALPAVYAATSPDAQPGRLYGPGGLGHLGGAPA-EQKLYPTLRGDEQADR 297 Query 301 LWEVSEQLTGVSYPK 315 +W VS++LT V +P+ Sbjct 298 IWRVSQELTAVPFPQ 312 >gi|255034640|ref|YP_003085261.1| short-chain dehydrogenase/reductase SDR [Dyadobacter fermentans DSM 18053] gi|254947396|gb|ACT92096.1| short-chain dehydrogenase/reductase SDR [Dyadobacter fermentans DSM 18053] Length=304 Score = 290 bits (743), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 157/313 (51%), Positives = 206/313 (66%), Gaps = 9/313 (2%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 M A +P + LAIITG+ G+GF A L++AG +V + RN KG + I+ Sbjct 1 MKNWTTADIPRTNSGLAIITGSTEGIGFEDALALASAGWNVTLMGRNPRKGTESTARIKQ 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 P AK++ + +DL+ L+S+ + ++++ G+ IDLLINNAGVMTPP+R+ TADGFELQF Sbjct 61 VNPLAKVSFEQIDLADLSSIKSFASRMISKGQAIDLLINNAGVMTPPKRLETADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 G+NH+GHFALTA LLPLLR ++ RVV++SS+A R G I+FDDLQ + +YAP AY QSK Sbjct 121 GTNHIGHFALTAQLLPLLRKSREGRVVTVSSIANREGTINFDDLQSKSAYAPGKAYSQSK 180 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LA LMFA EL R+S GWG+ S AAHPG+++TNL I G GR A M R F Sbjct 181 LANLMFALELQRQSEKHGWGVTSIAAHPGVSRTNLLITGA--GRWSAAGMAR------TF 232 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 PFL+Q +G LP LYAA +PQA GGA+YGP E G +K+PA A N DS Sbjct 233 LPFLFQPSAQGALPTLYAATSPQARGGAYYGPDRLMETRGFPAI-SKIPAQAENADDSLE 291 Query 301 LWEVSEQLTGVSY 313 LWE+S+ L V + Sbjct 292 LWEISKALAKVEF 304 >gi|332671412|ref|YP_004454420.1| short-chain dehydrogenase/reductase SDR [Cellulomonas fimi ATCC 484] gi|332340450|gb|AEE47033.1| short-chain dehydrogenase/reductase SDR [Cellulomonas fimi ATCC 484] Length=312 Score = 286 bits (731), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 161/307 (53%), Positives = 204/307 (67%), Gaps = 7/307 (2%) Query 3 KDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAV 62 +DL TVPDL+G A++TG + G+G +A RL+AAGAD+++ +RN KGEAAV IR V Sbjct 4 RDL--TVPDLTGTRAVLTGGSDGIGLRIATRLAAAGADLVLPVRNVRKGEAAVATIRATV 61 Query 63 PDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGS 122 P A +T+ +DL+SL SVAA GE L+ DGRP+ LL+NNAGVMTPP R TT DGFELQ G+ Sbjct 62 PGAAVTLHPMDLASLESVAAFGETLLRDGRPVHLLVNNAGVMTPPARQTTVDGFELQLGT 121 Query 123 NHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLA 182 NHLGH AL +HLLPLLRA RARV S S+AA RGRI +DDLQ+ER+Y M AY QSK+A Sbjct 122 NHLGHVALVSHLLPLLRAG-RARVTSQVSVAAARGRIRWDDLQWERTYDGMAAYRQSKIA 180 Query 183 VLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFA- 241 + +FA EL RRS AAGWG+ S HPG+ T+L A GR R + W A Sbjct 181 LGLFALELGRRSTAAGWGLTSTLTHPGVAPTSLLSARTELGRSDDTRAVRAIR--WLSAR 238 Query 242 PFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRL 301 L E LPALYAA +P A G Y P G + GG E ++ R++ +++R+ Sbjct 239 GILVGTPETAALPALYAATSPDARDGRMYAPSGPGHL-GGAPAEQRLYPTLRSEDEARRV 297 Query 302 WEVSEQL 308 W+VSEQ Sbjct 298 WDVSEQF 304 >gi|324998759|ref|ZP_08119871.1| short chain dehydrogenase [Pseudonocardia sp. P1] Length=313 Score = 285 bits (729), Expect = 6e-75, Method: Compositional matrix adjust. Identities = 162/305 (54%), Positives = 206/305 (68%), Gaps = 3/305 (0%) Query 8 TVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKL 67 TVPDL G+ ++TGA+ G+G G+A RL+AAGA+V+M +RN KGEAAV IR PDA + Sbjct 8 TVPDLRGRRTVVTGASDGVGLGIATRLAAAGAEVVMPVRNPRKGEAAVAGIRREHPDADV 67 Query 68 TIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGH 127 +++ LDLSSLASVAALGE L + RPI LL+NNAGVMTPP+R TTADGFELQ G+NHLGH Sbjct 68 SLRELDLSSLASVAALGETLRGEDRPIHLLVNNAGVMTPPDRKTTADGFELQLGTNHLGH 127 Query 128 FALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFA 187 AL HL+PLLRA R RV S S+AA RG IH+DD ++RSY AYGQSK+A+ +F Sbjct 128 VALVGHLMPLLRAG-RGRVTSQVSIAAARGAIHWDDPNWDRSYDGSRAYGQSKVALGLFG 186 Query 188 RELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLWQE 247 ELDRRSRA GWGI SN +HPG+ T+L A P GR + + + R+ L Sbjct 187 LELDRRSRAGGWGITSNLSHPGVVPTSLLSARPEVGRARDTPQVHVIRALSRWG-VLIGT 245 Query 248 IEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQ 307 + LPAL AA + A GG YG GGG E + R++ D+ R+W++S++ Sbjct 246 VATAQLPALLAATSADAQGGRLYG-PTGLGHLGGGPGEQDLYRPLRSEEDAARIWDLSQE 304 Query 308 LTGVS 312 LTGVS Sbjct 305 LTGVS 309 >gi|295689815|ref|YP_003593508.1| short-chain dehydrogenase/reductase SDR [Caulobacter segnis ATCC 21756] gi|295431718|gb|ADG10890.1| short-chain dehydrogenase/reductase SDR [Caulobacter segnis ATCC 21756] Length=304 Score = 285 bits (729), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 161/313 (52%), Positives = 199/313 (64%), Gaps = 10/313 (3%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 M K +P G+L ++TG GLG+ A L+ AGA V++A RN KG AV IR Sbjct 1 MTKWTTKKIPSQKGRLVVVTG-TGGLGYEDALALARAGASVVIAGRNPEKGAKAVAAIRE 59 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 VP A + +DL+ LAS+AA E+L + +DLLINNAGVMTPP+R T DGFELQF Sbjct 60 TVPGATVRFGQVDLADLASIAAFAEKLSGEQDQLDLLINNAGVMTPPQRRQTRDGFELQF 119 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 G+N+LGHFALTAHLLPLL+ + RVV+L S+AAR G I FDDLQ ER Y P Y QSK Sbjct 120 GTNYLGHFALTAHLLPLLKKGRSPRVVTLGSIAARGGAIDFDDLQAERDYKPFPVYSQSK 179 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LA ++FAREL RRS AAGWG+ S AHPG+T+T+L + G GR P+ M R RF Sbjct 180 LACILFARELSRRSGAAGWGVASIGAHPGVTRTDLILNG--AGRSSPSAMLR------RF 231 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 PFL+Q +G LP LYAA P A GA+YGP R G E K P A + + R Sbjct 232 LPFLFQPAWQGALPTLYAATDPAARDGAYYGP-DRLSGTRGYPTEEKPPEQALDANVAAR 290 Query 301 LWEVSEQLTGVSY 313 LWE S +LT V++ Sbjct 291 LWETSLRLTNVTF 303 >gi|284042532|ref|YP_003392872.1| short-chain dehydrogenase/reductase SDR [Conexibacter woesei DSM 14684] gi|283946753|gb|ADB49497.1| short-chain dehydrogenase/reductase SDR [Conexibacter woesei DSM 14684] Length=312 Score = 283 bits (724), Expect = 3e-74, Method: Compositional matrix adjust. Identities = 171/313 (55%), Positives = 201/313 (65%), Gaps = 25/313 (7%) Query 9 VPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKLT 68 +PD SG+LA++TGANSGLG A+ L +GA V++A R+ AKGEAA EIR A P A + Sbjct 10 IPDQSGRLAVVTGANSGLGLITAKELGRSGAHVVLACRDTAKGEAAAREIRGAAPQATIE 69 Query 69 IKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHF 128 + ALDL SLASV E+ + +DLL+NNAGVM PP R TTADGFELQ G+NHLGHF Sbjct 70 VAALDLGSLASVRDFAERFTGEHDRLDLLVNNAGVMAPPRR-TTADGFELQLGTNHLGHF 128 Query 129 ALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFAR 188 ALT L+ LRA ARVV+LSS A R G I FDDLQ ERSY AYGQSKLA LMFA Sbjct 129 ALTGLLIEQLRAQDGARVVTLSSGAHRFGAIDFDDLQRERSYNRWRAYGQSKLANLMFAF 188 Query 189 ELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYK-TSWRFAPFLWQE 247 ELDRR RAAG G++S AAHPG T+LQ A P + + K T+ FA Q Sbjct 189 ELDRRLRAAGSGLLSVAAHPGYAATHLQSAA------APTVDRVIMKATNALFA----QS 238 Query 248 IEEGILPALYAAATPQADGGAFYGP------RGRYEVAGGGVREAKVPAAARNDADSKRL 301 E G LP LYAA P GG F GP RG EV G AA+R++A + RL Sbjct 239 AEMGALPTLYAATAPSVAGGDFIGPDGFAEQRGHPEVVRGN-------AASRDEAVAARL 291 Query 302 WEVSEQLTGVSYP 314 W VSE+LTGV+YP Sbjct 292 WSVSEELTGVAYP 304 >gi|118468364|ref|YP_886565.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] gi|118169651|gb|ABK70547.1| short chain dehydrogenase [Mycobacterium smegmatis str. MC2 155] Length=314 Score = 282 bits (722), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 169/313 (54%), Positives = 217/313 (70%), Gaps = 5/313 (1%) Query 3 KDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAV 62 K + T+PDLSG+ A++TGA+ G+G G+A RL+AAGADVI+ +RN KG+AA+ +R Sbjct 4 KPIDVTLPDLSGRRAVVTGASDGIGLGIAARLAAAGADVILPVRNEIKGKAAIAAVRQTN 63 Query 63 PDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGS 122 AK++++ LDLSSLASVAALG+ L+ + +PI LLINNAGVMTPPER TT DGFE QFG+ Sbjct 64 AAAKVSLRELDLSSLASVAALGKSLLEEAQPIHLLINNAGVMTPPERRTTTDGFESQFGT 123 Query 123 NHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLA 182 NHLGHFAL AHLLPLLRA ARV S S+AA + I++DDL +ERSY AY QSK+A Sbjct 124 NHLGHFALVAHLLPLLRAGG-ARVTSQVSVAANQHAINWDDLNWERSYDGAKAYSQSKIA 182 Query 183 VLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKT-SWRFA 241 +F ELDRRS A GWGI SN +HPGL TNL A P GR + RL +T S R Sbjct 183 FGLFGLELDRRSHAHGWGITSNLSHPGLAPTNLLAARPDTGRAQDDWKLRLIRTLSSR-- 240 Query 242 PFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRL 301 L+ + LPALYAAA+P A G FYG GG E ++ + RN+ +++R+ Sbjct 241 GILFGTVHTAQLPALYAAASPHAKRGGFYG-PRGPGHLGGPPGEQRLYSRLRNNDEAQRI 299 Query 302 WEVSEQLTGVSYP 314 WE+SE+LT +S+P Sbjct 300 WEISEKLTDMSFP 312 >gi|297560298|ref|YP_003679272.1| short-chain dehydrogenase/reductase SDR [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296844746|gb|ADH66766.1| short-chain dehydrogenase/reductase SDR [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=315 Score = 280 bits (717), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 167/309 (55%), Positives = 211/309 (69%), Gaps = 7/309 (2%) Query 8 TVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKL 67 TVPDL+GK A++TGA+ G+G +ARRL+AAGA+VIM +RN KGE A+ IR VP A + Sbjct 9 TVPDLTGKRAVVTGASDGMGLAMARRLAAAGAEVIMPVRNPRKGEDAIARIRQTVPRANV 68 Query 68 TIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGH 127 +++ LDLSSLASVAALG+ L +G PI +LINNAGVM PP + TT DG ELQFG+NHLGH Sbjct 69 SLRGLDLSSLASVAALGDTLREEGLPIHILINNAGVMRPPNQQTTTDGHELQFGTNHLGH 128 Query 128 FALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFA 187 FAL H+LPLLRA RARV S S++ARRG I+++DL +ERSY M AY QSK+A +F Sbjct 129 FALVGHILPLLRAG-RARVTSQISVSARRGSINWEDLNWERSYNEMRAYSQSKIAFGLFG 187 Query 188 RELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGR--DKPALMERLYKTSWRFAPFLW 245 ELDRRS A GWGI SN +HPG+ T+L A P GR D P + R+ S R L Sbjct 188 LELDRRSTAHGWGITSNLSHPGVAPTSLLAARPEIGRSEDTP-YIRRIRALSARG--ILL 244 Query 246 QEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVS 305 +E LPAL AA P A GA Y P G + GG E ++ R+ ++ R+W+VS Sbjct 245 GTLETSKLPALMAATDPAAKRGALYSPSG-FGRLGGPPSEQRLYPPLRSAQEAARVWQVS 303 Query 306 EQLTGVSYP 314 E+LT VS+P Sbjct 304 EELTRVSFP 312 >gi|222084742|ref|YP_002543271.1| oxidoreductase protein [Agrobacterium radiobacter K84] gi|221722190|gb|ACM25346.1| oxidoreductase protein [Agrobacterium radiobacter K84] Length=315 Score = 280 bits (717), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 158/309 (52%), Positives = 202/309 (66%), Gaps = 4/309 (1%) Query 6 VATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDA 65 V +P +G+ A+ITGA SG+G+ A+ L+ AGA VI+A RN KG + EIR A P A Sbjct 6 VKDIPSQTGRTAVITGATSGIGYEAAKALAGAGARVIIASRNERKGAEVLAEIRAAAPGA 65 Query 66 KLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHL 125 + + LDL+SL SVA ++ A IDLLINNAG+M P+R T DGFE+Q G+N++ Sbjct 66 DIAFEPLDLASLVSVARAATRIAASAPRIDLLINNAGIMAIPDRHETEDGFEMQMGANYI 125 Query 126 GHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLM 185 GHFALT LLP L AA+ RVV++SSLA R G+I+FDDL +E SY+ AY QSKLA LM Sbjct 126 GHFALTMRLLPKLLAAKSPRVVTVSSLAHRSGKINFDDLHWEESYSAWRAYCQSKLATLM 185 Query 186 FARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLW 245 F+ ELDR +RA GW + S AAHPG T LQ GP GR++ +E + K P L Sbjct 186 FSLELDRIARAEGWNLTSTAAHPGYAITGLQSTGPRMGRNRAGWLELVGKA---IEPILS 242 Query 246 QEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVS 305 G LP L+AA +P A+GG YGP G YE+ G VR AK+ A+N+A +RLWEVS Sbjct 243 HSAAGGALPTLFAATSPIAEGGVMYGPDGFYELKGSPVR-AKIVPYAQNNAIWRRLWEVS 301 Query 306 EQLTGVSYP 314 EQLTG+ P Sbjct 302 EQLTGLKMP 310 >gi|296160842|ref|ZP_06843655.1| short-chain dehydrogenase/reductase SDR [Burkholderia sp. Ch1-1] gi|295888934|gb|EFG68739.1| short-chain dehydrogenase/reductase SDR [Burkholderia sp. Ch1-1] Length=317 Score = 280 bits (716), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 162/315 (52%), Positives = 207/315 (66%), Gaps = 8/315 (2%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 MA A +P +G+LA+ITGA GLGF A L+ AGA+V++ RN K +AA+ IR Sbjct 1 MANWTTADIPRQTGRLAVITGATGGLGFETALALAGAGANVVLTGRNEQKAQAALAAIRG 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 P A+++ LDL+SLASV EQ +DLLINNAGVM PP R TTADGFELQF Sbjct 61 RYPAAQISYAHLDLASLASVRGFAEQFAEGHAALDLLINNAGVMMPPTRQTTADGFELQF 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAAR-RGRIHFDDLQFERSYAPMTAYGQS 179 G+N+LGHFALT LLPLLRA + RVV+LSSLA + R IHFDDLQ++RSY P AY QS Sbjct 121 GTNYLGHFALTERLLPLLRAGREPRVVNLSSLAHKTRAAIHFDDLQWQRSYKPWPAYAQS 180 Query 180 KLAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWR 239 KLA+LMFA EL RRS A GWG++SNAAHPG +T+L GP G D +++ L + + Sbjct 181 KLAMLMFALELQRRSDANGWGLLSNAAHPGYARTDLIANGP--GADT--VLQMLNRVT-- 234 Query 240 FAPFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSK 299 F P Q +G LP L+AA P+A +YGP G +E+ G +A++ A++ A + Sbjct 235 FEPLASQSAADGALPTLFAATAPEARPAGYYGPSGFFELK-GPPGDAQIAPHAQDKAVAA 293 Query 300 RLWEVSEQLTGVSYP 314 RLW VSE LT +P Sbjct 294 RLWAVSEALTNARWP 308 >gi|284028017|ref|YP_003377948.1| short-chain dehydrogenase/reductase SDR [Kribbella flavida DSM 17836] gi|283807310|gb|ADB29149.1| short-chain dehydrogenase/reductase SDR [Kribbella flavida DSM 17836] Length=313 Score = 279 bits (713), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 169/307 (56%), Positives = 214/307 (70%), Gaps = 3/307 (0%) Query 8 TVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKL 67 TVPDL+G+ A++TGA+ G+G G+A RL+AAGA+V++ +RNR KGEAAV IR A P A + Sbjct 9 TVPDLTGQRAVVTGASDGIGLGIATRLAAAGAEVVLPVRNRRKGEAAVAAIRQAAPAAAV 68 Query 68 TIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGH 127 ++ LDLSSL +VAALG+ L GRPI LL+NNAGVMTPP+R TT DGFELQFG+NHLGH Sbjct 69 SLLDLDLSSLDAVAALGDTLRQAGRPIHLLVNNAGVMTPPDRQTTDDGFELQFGTNHLGH 128 Query 128 FALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFA 187 FAL A L PLLRA RARV S S+AA RG I++ DL ++RSY M AY QSK+ +FA Sbjct 129 FALVAQLFPLLRAG-RARVTSQISIAANRGAINWADLNWDRSYNGMKAYRQSKITFGLFA 187 Query 188 RELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLWQE 247 ELDRRSRAAGWGI SN +HPG+ TNL A P GRD L +L ++ L Sbjct 188 LELDRRSRAAGWGITSNLSHPGVAPTNLLAARPEVGRDHETLGRKLI-SALSARGILLGT 246 Query 248 IEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQ 307 +E PALYAA + +A+G YGP G V GG E K+ + N +++R+W++SE+ Sbjct 247 VESAGFPALYAATSTEAEGARLYGPSGPGHV-GGPPAEQKLYSPLSNLEEARRVWQLSEE 305 Query 308 LTGVSYP 314 LT VS P Sbjct 306 LTKVSLP 312 >gi|27376364|ref|NP_767893.1| dehydrogenase [Bradyrhizobium japonicum USDA 110] gi|27349504|dbj|BAC46518.1| dehydrogenase [Bradyrhizobium japonicum USDA 110] Length=312 Score = 276 bits (706), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 157/317 (50%), Positives = 199/317 (63%), Gaps = 16/317 (5%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 M A +P LSG+ A++TGA GLG+ A L+ AGA VI+ RN AKG A+E I Sbjct 1 MTDWTTADIPSLSGRTAVVTGATGGLGYETAMALAGAGAIVILTGRNDAKGLRAIEGICE 60 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 PDA + + LDL+SL+SVA ++ A +DLL+NNAGVM P+R T DGFE+Q Sbjct 61 RFPDALIAYEHLDLASLSSVADFAKRFAAGNEQLDLLVNNAGVMALPKRQQTEDGFEMQL 120 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 G+N+LGH+ALTA LLP LR A+ +R+V+LSSLA R G I+FDDLQ +RSY P AY QSK Sbjct 121 GTNYLGHYALTARLLPQLRRAKASRIVNLSSLAHRSGAINFDDLQGKRSYRPWRAYCQSK 180 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWR- 239 LA+LMFA EL RRS AAGWG+ S AAHPG +T+L GP WR Sbjct 181 LAMLMFALELQRRSLAAGWGVTSVAAHPGYARTDLIANGPGAN-----------TLQWRV 229 Query 240 ---FAPFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDA 296 PF+ Q EG LP L+AA +P A+ G +YGP YE+ G AK+ AR+ A Sbjct 230 GRWLQPFISQSAAEGALPTLFAATSPAAEPGGYYGPNRFYELKGPPA-PAKITPQARDFA 288 Query 297 DSKRLWEVSEQLTGVSY 313 + LW+VS LTGVS+ Sbjct 289 AAAMLWDVSATLTGVSF 305 >gi|114800019|ref|YP_760917.1| short chain dehydrogenase/reductase family oxidoreductase [Hyphomonas neptunium ATCC 15444] gi|114740193|gb|ABI78318.1| oxidoreductase, short chain dehydrogenase/reductase family [Hyphomonas neptunium ATCC 15444] Length=310 Score = 275 bits (702), Expect = 8e-72, Method: Compositional matrix adjust. Identities = 159/306 (52%), Positives = 197/306 (65%), Gaps = 10/306 (3%) Query 7 ATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAK 66 A +PD G+ A+ITG GLGF A L+ +GA V++A RN KG AV IR A P + Sbjct 13 AYIPDQRGRFAVITG-TGGLGFEGAVALARSGASVVLAGRNAHKGADAVAAIRQAAPASD 71 Query 67 LTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLG 126 + + LDL+ LASVA +L +DLLINNA VM PP R T DGFELQ G+N+LG Sbjct 72 IRYERLDLACLASVADFAARLRGQMDRLDLLINNAAVMNPPARQETEDGFELQLGTNYLG 131 Query 127 HFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMF 186 HFALT HLLPLLR ARV+S+SS+AAR G I+ +DLQ E+SY P +AY QSKLA LMF Sbjct 132 HFALTGHLLPLLRKGANARVISVSSIAARNGLINLEDLQAEQSYRPGSAYAQSKLACLMF 191 Query 187 ARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLWQ 246 A EL RRS+ GWG+ S AAHPG+++T L P GR PA + R W FL+Q Sbjct 192 ALELHRRSQLGGWGVASIAAHPGVSRTELLHNAP--GRGSPASLAR--SLLW----FLFQ 243 Query 247 EIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSE 306 ++G LP L+AA P+A GA+YGP G E G A++P A + A S RLWEVSE Sbjct 244 PADQGALPTLFAATWPEAKSGAYYGPHGLSETRGFPA-AAQIPPQALDAALSARLWEVSE 302 Query 307 QLTGVS 312 LTGV+ Sbjct 303 NLTGVT 308 >gi|115524813|ref|YP_781724.1| short-chain dehydrogenase/reductase SDR [Rhodopseudomonas palustris BisA53] gi|115518760|gb|ABJ06744.1| short-chain dehydrogenase/reductase SDR [Rhodopseudomonas palustris BisA53] Length=309 Score = 271 bits (692), Expect = 1e-70, Method: Compositional matrix adjust. Identities = 154/313 (50%), Positives = 202/313 (65%), Gaps = 13/313 (4%) Query 6 VATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDA 65 A +P SG+LA+ITGA GLGF AR L+ AGA++++ RN AKG A+ +R A P A Sbjct 6 TADMPSQSGRLAVITGATGGLGFETARALAGAGAEIVLTGRNAAKGADALARLRAAHPGA 65 Query 66 KLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHL 125 LD++SL SV A + ++A+GR +DLLINNAGVM P+R +ADGFELQF +N+L Sbjct 66 NARFALLDVASLGSVEAFAQTMLAEGRSVDLLINNAGVMALPQRQLSADGFELQFATNYL 125 Query 126 GHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLM 185 GHFALTA LLPLLR A ARVV+L+SLAA GRI DLQ E+SYAP YG +KL++LM Sbjct 126 GHFALTARLLPLLRRASGARVVNLASLAAHHGRIDLADLQAEQSYAPFGVYGMTKLSMLM 185 Query 186 FARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFA-PF- 243 FA EL RR AAGWG+ + AAHPG+ T++ GP+ + WR+ P Sbjct 186 FALELQRRGAAAGWGVDAIAAHPGMAATDIMRNGPAS--------SGVAAVVWRWVRPLI 237 Query 244 --LWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRL 301 L EEG +P L+AA +P+A GG +YGP +E G V A++P A + + L Sbjct 238 LPLNATAEEGAVPVLFAATSPEAQGGGYYGPSRSFETK-GPVAPARLPERALDQNVAAGL 296 Query 302 WEVSEQLTGVSYP 314 W+ SE+L GVS+P Sbjct 297 WQASERLAGVSFP 309 >gi|339024785|ref|ZP_08646691.1| oxidoreductase [Acetobacter tropicalis NBRC 101654] gi|338750211|dbj|GAA09995.1| oxidoreductase [Acetobacter tropicalis NBRC 101654] Length=286 Score = 270 bits (690), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 148/289 (52%), Positives = 187/289 (65%), Gaps = 9/289 (3%) Query 25 GLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKLTIKALDLSSLASVAALG 84 GLGF A L+ AG VI+A RN KG AV I+ P A ++ +ALDL+ L S+AA G Sbjct 6 GLGFEDALALARAGTTVILAGRNPGKGAEAVARIKRETPKASISFEALDLADLTSIAAFG 65 Query 85 EQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHFALTAHLLPLLRAAQRA 144 E+L + +D+LINNAGVM PP R T+DGFELQFG+N+LGHFALTAHLLPLLR Sbjct 66 ERLRSQHDHLDVLINNAGVMMPPTRKVTSDGFELQFGTNYLGHFALTAHLLPLLRKGHDP 125 Query 145 RVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFARELDRRSRAAGWGIISN 204 RVV+LSS+AAR GRI FDDLQ +Y PM Y QSKLA LMFA EL RRS A WGI S Sbjct 126 RVVTLSSIAARDGRITFDDLQATHNYKPMPVYSQSKLACLMFALELQRRSEAGNWGITSI 185 Query 205 AAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLWQEIEEGILPALYAAATPQA 264 AAHPG+++T+L +G +++ + W FL+Q +G L L+AA + +A Sbjct 186 AAHPGISRTDLL----PNGAGASSILGLARRILW----FLFQPAAQGALSTLFAATSSEA 237 Query 265 DGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQLTGVSY 313 GG +YGP E G AK+P AA + D+ RLW++SEQLT V + Sbjct 238 KGGCYYGPDKLSETRGYPT-AAKIPPAALDRQDAARLWDISEQLTDVQF 285 >gi|152966462|ref|YP_001362246.1| short chain dehydrogenase [Kineococcus radiotolerans SRS30216] gi|151360979|gb|ABS03982.1| short-chain dehydrogenase/reductase SDR [Kineococcus radiotolerans SRS30216] Length=326 Score = 269 bits (687), Expect = 5e-70, Method: Compositional matrix adjust. Identities = 160/309 (52%), Positives = 211/309 (69%), Gaps = 4/309 (1%) Query 8 TVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKL 67 VP L G+ A++TGA+ G+G LA RL+AAGAD+ + +RN+ KG AA+ IR AVP A++ Sbjct 9 NVPALVGRHAVVTGASDGVGLALATRLAAAGADLTLPVRNQVKGRAALAAIRRAVPGARV 68 Query 68 TIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGH 127 + LDLSSLASVAA G ++ +G+ I LL+NNAGVMTPP+R +T DGFELQFG+NHLGH Sbjct 69 VMADLDLSSLASVAAFGARMQEEGKAIHLLVNNAGVMTPPQRQSTVDGFELQFGTNHLGH 128 Query 128 FALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFA 187 AL AHLLPLLRA RARV S S+AAR GR++F+D + +Y M AY S +A +F Sbjct 129 VALVAHLLPLLRAG-RARVTSQVSVAARSGRVNFEDPNWRDAYHGMKAYSSSMIAFGLFG 187 Query 188 RELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLWQE 247 EL+RRSRA GWGI SN +HPG+ T+L A P GR R +T R+ L Sbjct 188 LELERRSRAQGWGITSNLSHPGIAPTSLLAARPEVGRSADTTQVRRIRTLSRWG--LVGT 245 Query 248 IEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQ 307 +E +LPAL AA + +++GG YGPRG ++ GG E K+ R+ AD+ +WE+SE Sbjct 246 VETALLPALMAATSQESEGGKLYGPRGPGHLS-GGPSEQKLYRPLRSTADAAHVWEISEA 304 Query 308 LTGVSYPKS 316 LTGVS+P+S Sbjct 305 LTGVSFPRS 313 >gi|269126055|ref|YP_003299425.1| short-chain dehydrogenase/reductase SDR [Thermomonospora curvata DSM 43183] gi|268311013|gb|ACY97387.1| short-chain dehydrogenase/reductase SDR [Thermomonospora curvata DSM 43183] Length=301 Score = 268 bits (685), Expect = 9e-70, Method: Compositional matrix adjust. Identities = 155/305 (51%), Positives = 199/305 (66%), Gaps = 14/305 (4%) Query 9 VPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKLT 68 +PDL+G+ AI+TGANSG+G+ A L+ GA V++A R+ +G AA+E IRTA+PDA + Sbjct 11 IPDLTGRRAIVTGANSGIGYHTALELARHGASVVLACRSAERGGAALERIRTALPDADVA 70 Query 69 IKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHF 128 + +LDL+ LASV A + G+ +D+L+NNAGVM P R TADGFE+QFG+NHLGHF Sbjct 71 LASLDLADLASVRAFADD--QGGQRLDILVNNAGVMAIPRR-RTADGFEMQFGTNHLGHF 127 Query 129 ALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFAR 188 ALT LLP LRAA RVV+++S+ A GRI FDDLQ ER Y AYGQSKLA L+FA+ Sbjct 128 ALTGLLLPALRAAPAPRVVTVTSMLAWAGRIDFDDLQGERRYGRWRAYGQSKLANLLFAK 187 Query 189 ELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLWQEI 248 ELDRR + S AAHPG TNLQ+ GP ++ ERL K + Q Sbjct 188 ELDRRVAE----VTSVAAHPGYAATNLQLVGPRMAGER--FTERLMKAA---NGLFAQSD 238 Query 249 EEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQL 308 +G LP+LYAA P GGA YGP R+ G + + P AA ++RLWEVSE+L Sbjct 239 ADGALPSLYAATAPDVRGGACYGP--RFLQQRGLPTQVRTPPAADRQDVARRLWEVSEKL 296 Query 309 TGVSY 313 TGV+Y Sbjct 297 TGVTY 301 >gi|299139839|ref|ZP_07033011.1| short-chain dehydrogenase/reductase SDR [Acidobacterium sp. MP5ACTX8] gi|298598193|gb|EFI54359.1| short-chain dehydrogenase/reductase SDR [Acidobacterium sp. MP5ACTX8] Length=313 Score = 267 bits (682), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 147/307 (48%), Positives = 200/307 (66%), Gaps = 8/307 (2%) Query 9 VPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKLT 68 +P +GK A+ITGANSG+G+ A L+ GA V++ +R+ KG+AA++ + VP A+ Sbjct 11 IPSQTGKTALITGANSGIGYQAAVELARHGAHVLLGVRSLEKGQAALDRLLREVPGAQAE 70 Query 69 IKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHF 128 + LD++SLAS+ ++ A GR +DLL+NNAGVM P R T DGFE QFG+NHLGHF Sbjct 71 LAVLDMASLASIRDFSQKFTAAGRGLDLLLNNAGVMALPTRELTPDGFERQFGTNHLGHF 130 Query 129 ALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFAR 188 ALT LLP A+ RVV+++SLA R G+I FD+LQ ERSYAP AY SKLA ++FAR Sbjct 131 ALTGLLLPRFLASTAPRVVTVASLAHRNGKIEFDNLQSERSYAPWDAYNNSKLANILFAR 190 Query 189 ELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHG-RDKPALMERLYKTSWRFAPFLWQE 247 ELDRR++AAG +IS HPG+++T + GP G +D ++ L AP + Q+ Sbjct 191 ELDRRAKAAGSRLISLPVHPGISRTAIVSNGPGTGSKDFKIMLLGL------LAPIITQD 244 Query 248 IEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQ 307 + G LP LYAA P+A GG + GP G E G +P A ++A +K+LW VSE+ Sbjct 245 DKMGALPTLYAATAPEAKGGEYIGPDGFKEFKGYPKVVQPLPRAL-DEAVAKKLWSVSEE 303 Query 308 LTGVSYP 314 LTGV YP Sbjct 304 LTGVKYP 310 >gi|159186572|ref|NP_396225.2| dehydrogenase [Agrobacterium tumefaciens str. C58] gi|159141632|gb|AAK90666.2| dehydrogenase [Agrobacterium tumefaciens str. C58] Length=301 Score = 267 bits (682), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 144/311 (47%), Positives = 203/311 (66%), Gaps = 10/311 (3%) Query 1 MAKDLVATVPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRT 60 M K A +P+ G+ A++TG GLG A L+ AG DV +A RN KG AV I+ Sbjct 1 MTKWTEANIPNQRGRSAVVTG-TGGLGLETALALARAGCDVTIAGRNPEKGSDAVSRIQR 59 Query 61 AVPDAKLTIKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQF 120 A P ++ + LDL+ L S+A +++ D +DLL+NNAG+M PP+R T DGFELQF Sbjct 60 AAPHVTVSFEKLDLADLTSIALFAQRMENDRESLDLLVNNAGIMVPPKRQETRDGFELQF 119 Query 121 GSNHLGHFALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSK 180 G+N+LGHFALTAHL+PLL+ ARVV++SS+AAR G+I+F D+ E++Y PM AY QSK Sbjct 120 GTNYLGHFALTAHLMPLLKKGTDARVVTVSSVAARAGKINFADINSEKNYHPMRAYSQSK 179 Query 181 LAVLMFARELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRF 240 LA LMFA EL RSRAAGWG+ S AAHPG+++T+L P GR+ ++ L +T F Sbjct 180 LACLMFALELQDRSRAAGWGVSSIAAHPGVSRTDLLHNAP--GRNS---LQGLART---F 231 Query 241 APFLWQEIEEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKR 300 FL+Q + +G LP L++A + + G +YGP R G + A++P A + K+ Sbjct 232 LWFLFQPVAQGALPQLFSATSKEVKSGGYYGP-DRLGETRGHPQPARIPPEALDRVAGKQ 290 Query 301 LWEVSEQLTGV 311 LWE+S+++TG+ Sbjct 291 LWEISQRMTGL 301 >gi|330809739|ref|YP_004354201.1| short chain dehydrogenase [Pseudomonas brassicacearum subsp. brassicacearum NFM421] gi|327377847|gb|AEA69197.1| putative short chain dehydrogenase [Pseudomonas brassicacearum subsp. brassicacearum NFM421] Length=316 Score = 266 bits (681), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 151/305 (50%), Positives = 196/305 (65%), Gaps = 9/305 (2%) Query 9 VPDLSGKLAIITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKLT 68 +P G++ +ITG SG+G+ A L+ AGA+VI+A RN +G A+ IR +VPDAK+ Sbjct 20 IPSQKGRIVLITGGTSGMGYEDALALARAGAEVIIAARNPERGAQAIARIRESVPDAKVQ 79 Query 69 IKALDLSSLASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHF 128 + +DL+ L+SV L ++L +D+LINNA VM PPER T+ADGFELQ +N+LGHF Sbjct 80 FENVDLADLSSVRDLAQRLNQRLPRLDVLINNAAVMAPPERGTSADGFELQLATNYLGHF 139 Query 129 ALTAHLLPLLRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFAR 188 ALT L+PLLR ++ ARVVSLSS+AA RG ++ DDLQ E+ Y P AY QSKLAVL +A Sbjct 140 ALTGLLVPLLRQSEDARVVSLSSIAAARGAMNLDDLQSEQKYDPYAAYAQSKLAVLHWAF 199 Query 189 ELDRRSRAAGWGIISNAAHPGLTKTNLQIAGPSHGRDKPALMERLYKTSWRFAPFLWQEI 248 L RRS A WGI S AAHPG+ T L GP ++ + W + Sbjct 200 ALQRRSDAENWGIRSMAAHPGVAVTELVARGPG--------LDSEFGRRWAKDRDAYHSA 251 Query 249 EEGILPALYAAATPQADGGAFYGPRGRYEVAGGGVREAKVPAAARNDADSKRLWEVSEQL 308 +G LP LYAA QA GGA+YGP G E G + AK P AA +AD++RLW VSE+L Sbjct 252 AQGALPTLYAATAAQAVGGAYYGPTGDDERR-GPLGFAKTPPAASTEADAERLWVVSERL 310 Query 309 TGVSY 313 TGV+Y Sbjct 311 TGVTY 315 Lambda K H 0.319 0.133 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 552325845108 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40