BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2287 Length=542 Score E Sequences producing significant alignments: (Bits) Value gi|15609424|ref|NP_216803.1| integral membrane transport protein... 1054 0.0 gi|289447921|ref|ZP_06437665.1| membrane transporter yjcE [Mycob... 1053 0.0 gi|289762448|ref|ZP_06521826.1| integral membrane transport prot... 1051 0.0 gi|289570404|ref|ZP_06450631.1| membrane transporter yjcE [Mycob... 1035 0.0 gi|294995543|ref|ZP_06801234.1| membrane transporter yjcE [Mycob... 1029 0.0 gi|183983426|ref|YP_001851717.1| integral membrane transport pro... 835 0.0 gi|240168751|ref|ZP_04747410.1| integral membrane transport prot... 802 0.0 gi|254818696|ref|ZP_05223697.1| Na+/H+ antiporter [Mycobacterium... 698 0.0 gi|296166254|ref|ZP_06848692.1| CPA1 family monovalent cation:pr... 686 0.0 gi|342857349|ref|ZP_08714005.1| Na+/H+ antiporter [Mycobacterium... 682 0.0 gi|118464955|ref|YP_881355.1| Na+/H+ antiporter [Mycobacterium a... 629 6e-178 gi|41408141|ref|NP_960977.1| YjcE [Mycobacterium avium subsp. pa... 622 3e-176 gi|336461766|gb|EGO40625.1| Na+ antiporter [Mycobacterium avium ... 622 6e-176 gi|315505790|ref|YP_004084677.1| na+/h+ antiporter [Micromonospo... 436 7e-120 gi|330467910|ref|YP_004405653.1| na+/h+ antiporter [Verrucosispo... 434 2e-119 gi|302867806|ref|YP_003836443.1| Na+/H+ antiporter [Micromonospo... 430 4e-118 gi|256378949|ref|YP_003102609.1| Na+/H+ antiporter [Actinosynnem... 350 3e-94 gi|331698653|ref|YP_004334892.1| Na+/H+ antiporter [Pseudonocard... 344 2e-92 gi|256392488|ref|YP_003114052.1| Na+/H+ antiporter [Catenulispor... 341 2e-91 gi|345011916|ref|YP_004814270.1| Na+/H+ antiporter [Streptomyces... 319 9e-85 gi|302557388|ref|ZP_07309730.1| Na+/H+ antiporter [Streptomyces ... 318 1e-84 gi|311112769|ref|YP_003983991.1| CPA1 family monovalent cation:p... 302 1e-79 gi|283458893|ref|YP_003363540.1| NhaP-type Na+/H+ and K+/H+ anti... 300 5e-79 gi|300744178|ref|ZP_07073197.1| Na+/H+ antiporter [Rothia dentoc... 297 4e-78 gi|269218631|ref|ZP_06162485.1| Na+/H+ antiporter [Actinomyces s... 291 2e-76 gi|323356615|ref|YP_004223011.1| NhaP-type Na+/H+ and K+/H+ anti... 283 5e-74 gi|255327461|ref|ZP_05368531.1| Na+/H+ antiporter [Rothia mucila... 275 1e-71 gi|311899714|dbj|BAJ32122.1| putative sodium/proton antiporter [... 275 2e-71 gi|297163002|gb|ADI12714.1| Na+/H+ antiporter [Streptomyces bing... 268 1e-69 gi|338209568|ref|YP_004653615.1| Na+/H+ antiporter [Runella slit... 265 1e-68 gi|196230022|ref|ZP_03128885.1| Na+/H+ antiporter [Chthoniobacte... 265 2e-68 gi|223939001|ref|ZP_03630886.1| Na+/H+ antiporter [bacterium Ell... 264 3e-68 gi|343522708|ref|ZP_08759674.1| Na+/H+ antiporter [Actinomyces s... 263 5e-68 gi|134101314|ref|YP_001106975.1| sodium/hydrogen antiporter [Sac... 258 2e-66 gi|326773839|ref|ZP_08233121.1| Na+/H+ antiporter [Actinomyces v... 256 5e-66 gi|325067898|ref|ZP_08126571.1| CPA1 family monovalent cation:pr... 253 5e-65 gi|329944091|ref|ZP_08292350.1| Na+/H+ antiporter [Actinomyces s... 251 2e-64 gi|312886601|ref|ZP_07746209.1| sodium/proton antiporter, CPA1 f... 249 7e-64 gi|256820476|ref|YP_003141755.1| Na+/H+ antiporter [Capnocytopha... 249 1e-63 gi|284046425|ref|YP_003396765.1| Na+/H+ antiporter [Conexibacter... 249 1e-63 gi|255036633|ref|YP_003087254.1| Na+/H+ antiporter [Dyadobacter ... 248 2e-63 gi|332879133|ref|ZP_08446834.1| Na+/H+ antiporter [Capnocytophag... 243 7e-62 gi|213962879|ref|ZP_03391139.1| Na+/H+ antiporter [Capnocytophag... 241 2e-61 gi|223694794|gb|ACN18076.1| Na+/H+ antiporter [uncultured bacter... 239 9e-61 gi|284047085|ref|YP_003397425.1| Na+/H+ antiporter [Conexibacter... 237 4e-60 gi|320532804|ref|ZP_08033583.1| Na+/H+ antiporter [Actinomyces s... 236 8e-60 gi|302038904|ref|YP_003799226.1| putative Na+/H+ antiporter [Can... 236 9e-60 gi|326800189|ref|YP_004318008.1| Na+/H+ antiporter [Sphingobacte... 234 2e-59 gi|320094094|ref|ZP_08025909.1| putative Na+/H+ antiporter [Acti... 234 3e-59 gi|299136008|ref|ZP_07029192.1| Na+/H+ antiporter [Acidobacteriu... 232 1e-58 >gi|15609424|ref|NP_216803.1| integral membrane transport protein YjcE [Mycobacterium tuberculosis H37Rv] gi|15841778|ref|NP_336815.1| Na+/H+ exchanger [Mycobacterium tuberculosis CDC1551] gi|31793465|ref|NP_855958.1| integral membrane transport protein YjcE [Mycobacterium bovis AF2122/97] 69 more sequence titles Length=542 Score = 1054 bits (2726), Expect = 0.0, Method: Compositional matrix adjust. Identities = 542/542 (100%), Positives = 542/542 (100%), Gaps = 0/542 (0%) Query 1 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDV 60 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDV Sbjct 1 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDV 60 Query 61 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME 120 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME Sbjct 61 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME 120 Query 121 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA 180 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA Sbjct 121 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA 180 Query 181 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL 240 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL Sbjct 181 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL 240 Query 241 KCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH 300 KCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH Sbjct 241 KCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH 300 Query 301 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS 360 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS Sbjct 301 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS 360 Query 361 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM 420 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM Sbjct 361 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM 420 Query 421 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS 480 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS Sbjct 421 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS 480 Query 481 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPAD 540 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPAD Sbjct 481 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPAD 540 Query 541 AE 542 AE Sbjct 541 AE 542 >gi|289447921|ref|ZP_06437665.1| membrane transporter yjcE [Mycobacterium tuberculosis CPHL_A] gi|289420879|gb|EFD18080.1| membrane transporter yjcE [Mycobacterium tuberculosis CPHL_A] Length=542 Score = 1053 bits (2722), Expect = 0.0, Method: Compositional matrix adjust. Identities = 541/542 (99%), Positives = 541/542 (99%), Gaps = 0/542 (0%) Query 1 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDV 60 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDV Sbjct 1 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDV 60 Query 61 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME 120 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME Sbjct 61 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME 120 Query 121 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA 180 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA Sbjct 121 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA 180 Query 181 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL 240 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL Sbjct 181 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL 240 Query 241 KCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH 300 KCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH Sbjct 241 KCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH 300 Query 301 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS 360 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS Sbjct 301 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS 360 Query 361 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM 420 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM Sbjct 361 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM 420 Query 421 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS 480 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS Sbjct 421 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS 480 Query 481 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPAD 540 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDI LRELQAAMDLEEVQLLDPAD Sbjct 481 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIALRELQAAMDLEEVQLLDPAD 540 Query 541 AE 542 AE Sbjct 541 AE 542 >gi|289762448|ref|ZP_06521826.1| integral membrane transport protein yjcE [Mycobacterium tuberculosis GM 1503] gi|289709954|gb|EFD73970.1| integral membrane transport protein yjcE [Mycobacterium tuberculosis GM 1503] Length=542 Score = 1051 bits (2717), Expect = 0.0, Method: Compositional matrix adjust. Identities = 541/542 (99%), Positives = 541/542 (99%), Gaps = 0/542 (0%) Query 1 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDV 60 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDV Sbjct 1 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDV 60 Query 61 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME 120 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME Sbjct 61 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME 120 Query 121 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA 180 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA Sbjct 121 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA 180 Query 181 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL 240 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL Sbjct 181 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL 240 Query 241 KCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH 300 KCSGVVAVLVSALVLTYV PTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH Sbjct 241 KCSGVVAVLVSALVLTYVVPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH 300 Query 301 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS 360 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS Sbjct 301 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS 360 Query 361 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM 420 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM Sbjct 361 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM 420 Query 421 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS 480 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS Sbjct 421 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS 480 Query 481 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPAD 540 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPAD Sbjct 481 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPAD 540 Query 541 AE 542 AE Sbjct 541 AE 542 >gi|289570404|ref|ZP_06450631.1| membrane transporter yjcE [Mycobacterium tuberculosis T17] gi|289544158|gb|EFD47806.1| membrane transporter yjcE [Mycobacterium tuberculosis T17] Length=542 Score = 1035 bits (2675), Expect = 0.0, Method: Compositional matrix adjust. Identities = 533/542 (99%), Positives = 533/542 (99%), Gaps = 0/542 (0%) Query 1 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDV 60 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRV GSLLGLIPRFGDV Sbjct 1 MNGRRTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVALQCCSSCPGSLLGLIPRFGDV 60 Query 61 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME 120 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME Sbjct 61 QIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGME 120 Query 121 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA 180 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA Sbjct 121 SHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA 180 Query 181 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL 240 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL Sbjct 181 GIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSL 240 Query 241 KCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH 300 KCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH Sbjct 241 KCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDH 300 Query 301 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS 360 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS Sbjct 301 IAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTS 360 Query 361 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM 420 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM Sbjct 361 WAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM 420 Query 421 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS 480 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS Sbjct 421 PEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADS 480 Query 481 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPAD 540 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPAD Sbjct 481 ATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPAD 540 Query 541 AE 542 AE Sbjct 541 AE 542 >gi|294995543|ref|ZP_06801234.1| membrane transporter yjcE [Mycobacterium tuberculosis 210] gi|297634881|ref|ZP_06952661.1| membrane transporter yjcE [Mycobacterium tuberculosis KZN 4207] gi|308404676|ref|ZP_07669438.1| membrane transporter yjcE [Mycobacterium tuberculosis SUMu012] gi|308365476|gb|EFP54327.1| membrane transporter yjcE [Mycobacterium tuberculosis SUMu012] gi|323719189|gb|EGB28334.1| integral membrane transporter YjcE [Mycobacterium tuberculosis CDC1551A] gi|339295196|gb|AEJ47307.1| integral membrane transport protein YjcE [Mycobacterium tuberculosis CCDC5079] gi|339298816|gb|AEJ50926.1| integral membrane transport protein YjcE [Mycobacterium tuberculosis CCDC5180] Length=530 Score = 1029 bits (2661), Expect = 0.0, Method: Compositional matrix adjust. Identities = 529/530 (99%), Positives = 530/530 (100%), Gaps = 0/530 (0%) Query 13 VFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL 72 +FGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL Sbjct 1 MFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL 60 Query 73 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 132 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS Sbjct 61 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 120 Query 133 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV 192 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV Sbjct 121 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV 180 Query 193 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA 252 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA Sbjct 181 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA 240 Query 253 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT 312 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT Sbjct 241 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT 300 Query 313 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA 372 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA Sbjct 301 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA 360 Query 373 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL 432 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL Sbjct 361 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL 420 Query 433 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV 492 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV Sbjct 421 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV 480 Query 493 RRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 RRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE Sbjct 481 RRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 530 >gi|183983426|ref|YP_001851717.1| integral membrane transport protein YjcE [Mycobacterium marinum M] gi|183176752|gb|ACC41862.1| conserved integral membrane transport protein YjcE [Mycobacterium marinum M] Length=530 Score = 835 bits (2157), Expect = 0.0, Method: Compositional matrix adjust. Identities = 449/530 (85%), Positives = 493/530 (94%), Gaps = 0/530 (0%) Query 13 VFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL 72 +FGLVVIVALVA VV+GTVLG RYRVGPPVLLIL G+LLGL+PRFGDVQIDGE+VLLLFL Sbjct 1 MFGLVVIVALVATVVIGTVLGRRYRVGPPVLLILLGALLGLVPRFGDVQIDGEIVLLLFL 60 Query 73 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 132 PAILYWES+NTSFRE+RWNLR+++MFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS Sbjct 61 PAILYWESLNTSFRELRWNLRIVIMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 120 Query 133 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV 192 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEG+A +GPAAL GRFV Sbjct 121 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGSAQLGPAALAGRFV 180 Query 193 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA 252 VSYLGGI+AGLLVGGLVT+LRR+IDAPLEEGALSLLTPFAAFLLAQS+ CSGVVAVL+SA Sbjct 181 VSYLGGIVAGLLVGGLVTMLRRKIDAPLEEGALSLLTPFAAFLLAQSMHCSGVVAVLISA 240 Query 253 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT 312 LVLTY GP VIRARSR+Q++AFWDI TFLINGSLWVFVGVQIPGAIDHI+ DGGL RAT Sbjct 241 LVLTYTGPRVIRARSRMQSYAFWDITTFLINGSLWVFVGVQIPGAIDHISNVDGGLRRAT 300 Query 313 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA 372 +ALAVTGV+IATRI WV+ TTVLG +DR LKK TRHVGFRQRC+TSWAGFRGAVSLAA Sbjct 301 FIALAVTGVIIATRIVWVEVTTVLGVALDRFLKKDTRHVGFRQRCITSWAGFRGAVSLAA 360 Query 373 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL 432 ALAVPMTT+SGAPFPDRNLIIFVVSVVILVTVLVQG+SLP VVRWAR+P DVAHA+E+QL Sbjct 361 ALAVPMTTHSGAPFPDRNLIIFVVSVVILVTVLVQGSSLPAVVRWARVPGDVAHADEVQL 420 Query 433 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV 492 ARTRSA+AAL+ LP VA ELGV+PDL+K L KEYEERA ++ +G DSA SDLA+R DLV Sbjct 421 ARTRSAEAALEVLPDVASELGVSPDLLKRLTKEYEERATIIRENGDDSAPSDLAQRTDLV 480 Query 493 RRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 RRVRLGVL+HQR A+T LRNQNLIDDIVLRE+QA MDLEEVQLLDP + + Sbjct 481 RRVRLGVLEHQRHAITALRNQNLIDDIVLREVQADMDLEEVQLLDPVEHD 530 >gi|240168751|ref|ZP_04747410.1| integral membrane transport protein YjcE [Mycobacterium kansasii ATCC 12478] Length=530 Score = 802 bits (2072), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/530 (84%), Positives = 486/530 (92%), Gaps = 0/530 (0%) Query 13 VFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL 72 +FGLVVIV LVA VV GTVLG RYRVGPPVLLIL G+LLGLIPRFG V+IDGE+VLLLFL Sbjct 1 MFGLVVIVTLVAIVVAGTVLGRRYRVGPPVLLILLGALLGLIPRFGSVEIDGEIVLLLFL 60 Query 73 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 132 PAILYWES+NTSFREIRWNLRVI+MFS+GLVIATAVAVSWTARA GMESHAAAVLGAVLS Sbjct 61 PAILYWESLNTSFREIRWNLRVIIMFSVGLVIATAVAVSWTARAFGMESHAAAVLGAVLS 120 Query 133 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV 192 PTDAAAVAGLAKRLPRR LTVL+GESLINDGTALVLFAVTVAVAEGA GIGPAALVGRFV Sbjct 121 PTDAAAVAGLAKRLPRRTLTVLKGESLINDGTALVLFAVTVAVAEGAPGIGPAALVGRFV 180 Query 193 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA 252 VSYLGGI AGLLVGGLVT+LRRRIDAPLEEGALS++TPFAAFLLAQSL CSGVVAV+VSA Sbjct 181 VSYLGGITAGLLVGGLVTMLRRRIDAPLEEGALSMMTPFAAFLLAQSLHCSGVVAVMVSA 240 Query 253 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT 312 LVL Y GP VIRARSRLQ+ AFWDI+TFLINGSLWVFVGVQIPGAI+HI+ GGL RAT Sbjct 241 LVLAYTGPRVIRARSRLQSFAFWDISTFLINGSLWVFVGVQIPGAIEHISDVGGGLRRAT 300 Query 313 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA 372 VLAL V GVV+ATRI WV+ T+++G VDR ++KP R+VGFRQRCVTSWAGFRGAVSLAA Sbjct 301 VLALVVAGVVVATRIVWVEVTSLVGRAVDRSMRKPHRYVGFRQRCVTSWAGFRGAVSLAA 360 Query 373 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL 432 ALAVPMTT SGAPFPDRNLIIFVVS+VILVTVLVQG+SLP VVRWARMP+DV A+ELQL Sbjct 361 ALAVPMTTRSGAPFPDRNLIIFVVSIVILVTVLVQGSSLPAVVRWARMPDDVTRADELQL 420 Query 433 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV 492 ARTRSA+AAL+ALP VAD LG ++VK L+++YEERA LV A GADSATSDLA + DLV Sbjct 421 ARTRSAEAALEALPAVADALGAGTEVVKRLQRDYEERAELVGASGADSATSDLAAQCDLV 480 Query 493 RRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 R+VRLGVLQ+QRQAVT LRN+NLIDDIVLRE+QA MDL+EVQLLDPADAE Sbjct 481 RQVRLGVLQYQRQAVTALRNKNLIDDIVLREVQAEMDLQEVQLLDPADAE 530 >gi|254818696|ref|ZP_05223697.1| Na+/H+ antiporter [Mycobacterium intracellulare ATCC 13950] Length=558 Score = 698 bits (1801), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/538 (72%), Positives = 444/538 (83%), Gaps = 0/538 (0%) Query 5 RTIGEDGLVFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDG 64 R I +DGLVFGL +IVALV+ V+VGTV+G RYRVGPPVLLIL G LLGL+P FG V+++G Sbjct 17 RVIRQDGLVFGLELIVALVSTVIVGTVIGRRYRVGPPVLLILMGVLLGLVPHFGHVRVNG 76 Query 65 EVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAA 124 E+VLLLFLPAILYWE +NTSFREIR N R+IV S+ LVIATAVAVSWTARALGM HAA Sbjct 77 EIVLLLFLPAILYWEGLNTSFREIRANARIIVFLSVALVIATAVAVSWTARALGMNPHAA 136 Query 125 AVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGP 184 VLGAVLSPTDAAAVAGLAK+LPRRALTVL+ ESLINDGTALVLFAV+V VA G A I P Sbjct 137 GVLGAVLSPTDAAAVAGLAKKLPRRALTVLKAESLINDGTALVLFAVSVHVAIGGAAISP 196 Query 185 AALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSG 244 + RF+ SYLGGI AGLLVGG VTLLR+RIDAP EEGALSL+TPFAAFLLAQS++CSG Sbjct 197 PEVTARFIGSYLGGIAAGLLVGGAVTLLRKRIDAPQEEGALSLVTPFAAFLLAQSMECSG 256 Query 245 VVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGE 304 VVAV+VSALVL Y GP VIRARSRLQ+ AFWDIATFL+NGSLWVFVGVQIPGA+ IAG Sbjct 257 VVAVMVSALVLAYAGPVVIRARSRLQSSAFWDIATFLLNGSLWVFVGVQIPGALRGIAGV 316 Query 305 DGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGF 364 DGG+ A +AL VT VVI +RI W + TT+L +DR + R V +RQR VT WAGF Sbjct 317 DGGIRHALFVALVVTAVVIVSRIFWGEITTLLIRLIDRRQVQRERRVNWRQRFVTVWAGF 376 Query 365 RGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDV 424 RGAVSLAAA+AVPMTT SGAPFPDR+L+IF+V+VVILVTVLVQG++LP VVRWA+MPED Sbjct 377 RGAVSLAAAVAVPMTTLSGAPFPDRSLLIFIVTVVILVTVLVQGSTLPAVVRWAKMPEDA 436 Query 425 AHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSD 484 HA ELQLAR R +QAAL ALPTVADE+G++ DL + L+ EYEE+A LV+A S Sbjct 437 THAEELQLARCRGSQAALAALPTVADEVGISDDLRRRLQTEYEEKAALVLATEDGSTDHR 496 Query 485 LAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 + + + VR+VRLGVL+H+R+ +T LRNQNLIDDIVLRELQ MDLEEVQLL A E Sbjct 497 ILKGREKVRQVRLGVLEHKRREITALRNQNLIDDIVLRELQNEMDLEEVQLLAAAADE 554 >gi|296166254|ref|ZP_06848692.1| CPA1 family monovalent cation:proton (H+) antiporter-1 [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295898349|gb|EFG77917.1| CPA1 family monovalent cation:proton (H+) antiporter-1 [Mycobacterium parascrofulaceum ATCC BAA-614] Length=530 Score = 686 bits (1769), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/530 (75%), Positives = 447/530 (85%), Gaps = 0/530 (0%) Query 13 VFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL 72 +FGLV+IVALV+ V+VGTVLG RYRVGPPVLLI+ G+LLGLIP F V I+GE+VLLLFL Sbjct 1 MFGLVLIVALVSTVIVGTVLGRRYRVGPPVLLIVLGTLLGLIPSFAHVHINGEIVLLLFL 60 Query 73 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 132 PAILYWE +NTSFREIR N R+IV S+ LVIATAVAVSWTARALGM+SH AAVLGAVLS Sbjct 61 PAILYWEGLNTSFREIRANARIIVFLSVALVIATAVAVSWTARALGMDSHTAAVLGAVLS 120 Query 133 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV 192 PTDAAAVAGLAK+LPRR++TVL+ ESLINDGTALVLFAVTV VA G + IGP LV RFV Sbjct 121 PTDAAAVAGLAKKLPRRSVTVLKAESLINDGTALVLFAVTVHVAIGGSAIGPTDLVVRFV 180 Query 193 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA 252 SYLGGI AGLLVGG VTLLR+RIDAP EEGALSLLTPFAAFLLAQS++CSGVVAV+V+A Sbjct 181 GSYLGGIAAGLLVGGAVTLLRKRIDAPQEEGALSLLTPFAAFLLAQSMECSGVVAVMVAA 240 Query 253 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT 312 LVL Y GP VIRARSRLQA+AFWD ATFL+NGSLWVFVGVQIPGA+ IAG DGG+ A Sbjct 241 LVLAYAGPVVIRARSRLQAYAFWDSATFLLNGSLWVFVGVQIPGALRGIAGVDGGIRHAL 300 Query 313 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA 372 +ALAVT VVI +RI W + T +L +DR + R VG+RQR VT+WAGFRGAVSLAA Sbjct 301 FIALAVTAVVILSRIFWGEITVLLIRLIDRREVQRERRVGWRQRFVTAWAGFRGAVSLAA 360 Query 373 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL 432 ALAVP TT SGAPFPDR+L+IFVV VVILVTVLVQGT+LP VVRWA+MPED+AHA ELQL Sbjct 361 ALAVPTTTLSGAPFPDRSLLIFVVVVVILVTVLVQGTTLPAVVRWAKMPEDLAHAEELQL 420 Query 433 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV 492 ARTR +AALDALPTVADE+G+ DL + L+KEYEE+A L +A S L ++ DLV Sbjct 421 ARTRGVRAALDALPTVADEVGIGDDLRRRLQKEYEEKAALALATEDGSTGDHLVKKKDLV 480 Query 493 RRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 RRVRLGVL+ +R+ +T LRN+NLIDDIVLRELQ MDLEEVQLLD AD E Sbjct 481 RRVRLGVLEQKRREITALRNRNLIDDIVLRELQNEMDLEEVQLLDAADNE 530 >gi|342857349|ref|ZP_08714005.1| Na+/H+ antiporter [Mycobacterium colombiense CECT 3035] gi|342134682|gb|EGT87848.1| Na+/H+ antiporter [Mycobacterium colombiense CECT 3035] Length=534 Score = 682 bits (1761), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/534 (71%), Positives = 440/534 (83%), Gaps = 4/534 (0%) Query 13 VFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL 72 +FGLV+IVALV+ V+VGTV+G RYRVGPPVLLI+ G+LLGL+P+ G + ++GEVVLLLFL Sbjct 1 MFGLVLIVALVSTVIVGTVIGRRYRVGPPVLLIVLGALLGLVPQLGQIHVNGEVVLLLFL 60 Query 73 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 132 PAILYWE +NTSFREIR N R+IV S+ LVIATAVAVSWTARALGM HAA VLGAVLS Sbjct 61 PAILYWEGLNTSFREIRANARIIVFLSVVLVIATAVAVSWTARALGMNPHAAGVLGAVLS 120 Query 133 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV 192 PTDAAAVAGLAK+LPRR+LTVL+ ESLINDGTALVLFAV+V VA G A I P + RF+ Sbjct 121 PTDAAAVAGLAKKLPRRSLTVLKAESLINDGTALVLFAVSVHVAVGGAAISPPEVTARFI 180 Query 193 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA 252 SYLGGI AGLLVGG VTLLR+RIDAP EEGALSL+TPFAAFLLAQS+ CSGVVAV+VSA Sbjct 181 GSYLGGIAAGLLVGGAVTLLRKRIDAPQEEGALSLVTPFAAFLLAQSMDCSGVVAVMVSA 240 Query 253 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT 312 LVL Y GP VIRARSRLQ+ AFWDIATFL+NGSLWVFVGVQIPGA+ IAG DGG+ A Sbjct 241 LVLAYAGPVVIRARSRLQSSAFWDIATFLLNGSLWVFVGVQIPGALRGIAGVDGGIRHAL 300 Query 313 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA 372 +AL VTGVVI +RI W + TT+L +DR + R + +RQR VT WAGFRGAVSLAA Sbjct 301 FVALVVTGVVIVSRIFWGEITTLLIRLIDRRQVQRERRINWRQRFVTVWAGFRGAVSLAA 360 Query 373 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL 432 A+AVP+TT +G PFPDR+L+IF+V VVILVTVLVQG++LP VVRWA+MPED HA ELQL Sbjct 361 AVAVPITTLNGDPFPDRSLLIFIVVVVILVTVLVQGSTLPAVVRWAKMPEDATHAEELQL 420 Query 433 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV 492 AR R +QAAL ALPTVADE+G++ +L + L+KEYEE+A LV+A S + + + + V Sbjct 421 ARCRGSQAALAALPTVADEVGISDELRRRLQKEYEEKAALVLATENGSPDNRILKGREKV 480 Query 493 RRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLL----DPADAE 542 RRVRLGVL+H+R+ +T LRNQNLIDDIVLRELQ MDLEEVQLL D D E Sbjct 481 RRVRLGVLEHKRREITALRNQNLIDDIVLRELQNEMDLEEVQLLAAAIDDGDEE 534 >gi|118464955|ref|YP_881355.1| Na+/H+ antiporter [Mycobacterium avium 104] gi|254774857|ref|ZP_05216373.1| Na+/H+ antiporter [Mycobacterium avium subsp. avium ATCC 25291] gi|118166242|gb|ABK67139.1| Na+/H+ antiporter [Mycobacterium avium 104] Length=536 Score = 629 bits (1621), Expect = 6e-178, Method: Compositional matrix adjust. Identities = 380/524 (73%), Positives = 444/524 (85%), Gaps = 0/524 (0%) Query 13 VFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL 72 +FGLV+IVALV+ V+VGTV+G RYRVGPPVLLI+ G LLGL+P+FG V+IDGE+VLLLFL Sbjct 1 MFGLVLIVALVSTVIVGTVIGRRYRVGPPVLLIVLGVLLGLVPQFGHVRIDGEIVLLLFL 60 Query 73 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 132 PAILYWE +N SFREIR N R+IV S+ LVIATAVAVSWTARALGM+ HAA VLGAVLS Sbjct 61 PAILYWEGLNISFREIRANARIIVFLSVALVIATAVAVSWTARALGMDPHAAGVLGAVLS 120 Query 133 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV 192 PTDAAAVAGLAK+LPRR+LTVL+ ESLINDGTALVLFAV+V VA GA I P + RF+ Sbjct 121 PTDAAAVAGLAKKLPRRSLTVLKAESLINDGTALVLFAVSVHVAIGAPAISPPEVTLRFI 180 Query 193 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA 252 SYLGGI AGLLVGG VTL+R+RIDAP EEGALSL+TPFAAFLLAQS++CSGVVAV+VSA Sbjct 181 GSYLGGIAAGLLVGGAVTLVRKRIDAPQEEGALSLVTPFAAFLLAQSVECSGVVAVVVSA 240 Query 253 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT 312 LVL Y GP VIRARSRLQ++AFWDIATFL+NGSLWVFVGVQIPGA+ IAG DGG+ A Sbjct 241 LVLAYSGPVVIRARSRLQSYAFWDIATFLLNGSLWVFVGVQIPGALRGIAGVDGGVRHAL 300 Query 313 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA 372 +AL +TGVVI +RI W + TT+L +DR + R VG+RQR VT+WAGFRGAVSLAA Sbjct 301 FVALVITGVVIVSRIFWGEFTTMLIRLIDRRAVQRERRVGWRQRFVTAWAGFRGAVSLAA 360 Query 373 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL 432 A+AVPMTT SGAPFPDR+L+IF+V+VVILVTVLVQG++LP VVRWAR+P DVAHA ELQL Sbjct 361 AVAVPMTTLSGAPFPDRSLLIFIVTVVILVTVLVQGSTLPAVVRWARLPADVAHAEELQL 420 Query 433 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV 492 ARTR+A+AALDALP VADE+GV+ +L + L KEYEE+A LV+A S + + + + V Sbjct 421 ARTRAARAALDALPAVADEVGVSDELRRRLHKEYEEKAALVLATENGSPDNRILKTREKV 480 Query 493 RRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLL 536 R+VRLGVL+H+R+ VT LRNQN IDD VLRELQ MDLEEVQLL Sbjct 481 RQVRLGVLEHKRREVTALRNQNRIDDTVLRELQNEMDLEEVQLL 524 >gi|41408141|ref|NP_960977.1| YjcE [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396496|gb|AAS04360.1| YjcE [Mycobacterium avium subsp. paratuberculosis K-10] Length=536 Score = 622 bits (1605), Expect = 3e-176, Method: Compositional matrix adjust. Identities = 378/524 (73%), Positives = 442/524 (85%), Gaps = 0/524 (0%) Query 13 VFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL 72 +FGLV+IVALV+ V+VGTV+G RYRVGPPVLLI+ G LLGL+P+FG V+IDGE+VLLLFL Sbjct 1 MFGLVLIVALVSTVIVGTVIGRRYRVGPPVLLIVLGVLLGLVPQFGHVRIDGEIVLLLFL 60 Query 73 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 132 PAILYWE +N SFREIR N R+IV S+ LVIATAVAVSWTARALGM+ HAA VLGAVLS Sbjct 61 PAILYWEGLNISFREIRANARIIVFLSVALVIATAVAVSWTARALGMDPHAAGVLGAVLS 120 Query 133 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV 192 PTDAAAVAGLAK+LPRR+LTVL+ ESLINDGTALVLFAV+V VA GA I P + RF+ Sbjct 121 PTDAAAVAGLAKKLPRRSLTVLKAESLINDGTALVLFAVSVHVAIGAPAISPPEVTLRFI 180 Query 193 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA 252 SYLGGI AGLLVGG VTL+R+RIDAP EEGALSL+TPFAAFLLAQS++CSGVVAV+VSA Sbjct 181 GSYLGGIAAGLLVGGAVTLVRKRIDAPQEEGALSLVTPFAAFLLAQSVECSGVVAVVVSA 240 Query 253 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT 312 LVL Y GP VIRARSRLQ++AFWDIATFL+NGSLWVFVGVQIPGA+ IAG DGG+ A Sbjct 241 LVLAYSGPVVIRARSRLQSYAFWDIATFLLNGSLWVFVGVQIPGALRGIAGVDGGVRHAL 300 Query 313 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA 372 +AL +TGVVI +RI W + TT+L +DR + R VG+RQR VT+WAGFRGAVSLAA Sbjct 301 FVALVITGVVIVSRIFWGEFTTMLIRLIDRRAVQRERRVGWRQRFVTAWAGFRGAVSLAA 360 Query 373 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL 432 A+AVPMTT SGAPFPD +L+IF+V+VVILVTVLVQG++LP VVRWAR+P DVAHA ELQL Sbjct 361 AVAVPMTTLSGAPFPDHSLLIFIVTVVILVTVLVQGSTLPAVVRWARLPADVAHAEELQL 420 Query 433 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV 492 ARTR+A+AAL ALP VADE+GV+ +L + L KEYEE+A LV+A S + + + + V Sbjct 421 ARTRAARAALAALPAVADEVGVSDELRRRLHKEYEEKAALVLATENGSPDNRILKTREKV 480 Query 493 RRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLL 536 R+VRLGVL+H+R+ VT LRNQN IDD VLRELQ MDLEEVQLL Sbjct 481 RQVRLGVLEHKRREVTALRNQNRIDDTVLRELQNEMDLEEVQLL 524 >gi|336461766|gb|EGO40625.1| Na+ antiporter [Mycobacterium avium subsp. paratuberculosis S397] Length=536 Score = 622 bits (1603), Expect = 6e-176, Method: Compositional matrix adjust. Identities = 377/524 (72%), Positives = 441/524 (85%), Gaps = 0/524 (0%) Query 13 VFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL 72 +FGLV+IVALV+ V+VGTV+G RYRVGPPVLLI+ G LLGL+P+FG V+IDGE+VLLLF Sbjct 1 MFGLVLIVALVSTVIVGTVIGRRYRVGPPVLLIVLGVLLGLVPQFGHVRIDGEIVLLLFF 60 Query 73 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 132 PAILYWE +N SFREIR N R+IV S+ LVIATAVAVSWTARALGM+ HAA VLGAVLS Sbjct 61 PAILYWEGLNISFREIRANARIIVFLSVALVIATAVAVSWTARALGMDPHAAGVLGAVLS 120 Query 133 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV 192 PTDAAAVAGLAK+LPRR+LTVL+ ESLINDGTALVLFAV+V VA GA I P + RF+ Sbjct 121 PTDAAAVAGLAKKLPRRSLTVLKAESLINDGTALVLFAVSVHVAIGAPAISPPEVTLRFI 180 Query 193 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA 252 SYLGGI AGLLVGG VTL+R+RIDAP EEGALSL+TPFAAFLLAQS++CSGVVAV+VSA Sbjct 181 GSYLGGIAAGLLVGGAVTLVRKRIDAPQEEGALSLVTPFAAFLLAQSVECSGVVAVVVSA 240 Query 253 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT 312 LVL Y GP VIRARSRLQ++AFWDIATFL+NGSLWVFVGVQIPGA+ IAG DGG+ A Sbjct 241 LVLAYSGPVVIRARSRLQSYAFWDIATFLLNGSLWVFVGVQIPGALRGIAGVDGGVRHAL 300 Query 313 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA 372 +AL +TGVVI +RI W + TT+L +DR + R VG+RQR VT+WAGFRGAVSLAA Sbjct 301 FVALVITGVVIVSRIFWGEFTTMLIRLIDRRAVQRERRVGWRQRFVTAWAGFRGAVSLAA 360 Query 373 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL 432 A+AVPMTT SGAPFPD +L+IF+V+VVILVTVLVQG++LP VVRWAR+P DVAHA ELQL Sbjct 361 AVAVPMTTLSGAPFPDHSLLIFIVTVVILVTVLVQGSTLPAVVRWARLPADVAHAEELQL 420 Query 433 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV 492 ARTR+A+AAL ALP VADE+GV+ +L + L KEYEE+A LV+A S + + + + V Sbjct 421 ARTRAARAALAALPAVADEVGVSDELRRRLHKEYEEKAALVLATENGSPDNRILKTREKV 480 Query 493 RRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLL 536 R+VRLGVL+H+R+ VT LRNQN IDD VLRELQ MDLEEVQLL Sbjct 481 RQVRLGVLEHKRREVTALRNQNRIDDTVLRELQNEMDLEEVQLL 524 >gi|315505790|ref|YP_004084677.1| na+/h+ antiporter [Micromonospora sp. L5] gi|315412409|gb|ADU10526.1| Na+/H+ antiporter [Micromonospora sp. L5] Length=520 Score = 436 bits (1120), Expect = 7e-120, Method: Compositional matrix adjust. Identities = 276/527 (53%), Positives = 358/527 (68%), Gaps = 8/527 (1%) Query 17 VVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAIL 76 ++I L A V+VGT +G RY V PPVLLI G+L+GL+P F ++ ++ EVVL+LFLPAIL Sbjct 1 MLITVLGATVLVGTTIGGRYSVAPPVLLIAMGALIGLLPPFENLILEPEVVLVLFLPAIL 60 Query 77 YWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDA 136 Y ES+ S REIR NL VIV ++ LVI T VAV++TA+ALG++ AA VLGAVL+PTDA Sbjct 61 YRESLVISLREIRANLTVIVGLAVVLVIVTMVAVAYTAQALGVQPAAAWVLGAVLAPTDA 120 Query 137 AAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYL 196 AAVAGLAKR+PR LT LR ESL+NDGTALVLFAV V G G L G FV Sbjct 121 AAVAGLAKRMPRGILTTLRAESLVNDGTALVLFAVAAGVVAGGTVPGALTLSGEFVGKSA 180 Query 197 GGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLT 256 GG+ AGLLVG +V L+R+ +D P+ EG LS+LTPF AFLLA ++ SGV+AV+VS L+L+ Sbjct 181 GGVAAGLLVGAVVVLIRKHVDDPMREGGLSILTPFVAFLLADAVHASGVLAVVVSGLLLS 240 Query 257 YVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATV-LA 315 Y P VIRARSR+ A AFWD++TF+ING L+V +G Q+P ++ I P A++ +A Sbjct 241 YAAPRVIRARSRVTAFAFWDLSTFMINGGLFVLLGTQVPRSLRSITSHS---PTASLGIA 297 Query 316 LAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALA 375 + V VV+A R+ WV + VDR RH R R WAGFRGAVSLAAALA Sbjct 298 VLVAAVVVAIRLLWVHLSVSALQRVDRRESSRARHFDGRMRTAVGWAGFRGAVSLAAALA 357 Query 376 VPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLART 435 VP+T + G+P +R+LIIFV VVI++ +LVQGT+LP VV WA + D E++ AR Sbjct 358 VPVTMHDGSPVRERDLIIFVTVVVIVLIMLVQGTTLPAVVSWAGLTGDRERDEEVRWARI 417 Query 436 RSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLVRRV 495 R+ +AAL+ALP A ++G D V L +YE+ +AD D D ++ RR+ Sbjct 418 RATEAALEALPRAASDVGATQDTVDRLRADYEDH----LADARDPGGEDAEAEREMARRL 473 Query 496 RLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 RL VL H+RQ +T LRN IDD VLR+LQAA+D+EE++LL P E Sbjct 474 RLRVLDHKRQEITRLRNTRQIDDAVLRQLQAAIDIEEIRLLGPEMEE 520 >gi|330467910|ref|YP_004405653.1| na+/h+ antiporter [Verrucosispora maris AB-18-032] gi|328810881|gb|AEB45053.1| na+/h+ antiporter [Verrucosispora maris AB-18-032] Length=523 Score = 434 bits (1117), Expect = 2e-119, Method: Compositional matrix adjust. Identities = 269/528 (51%), Positives = 359/528 (68%), Gaps = 9/528 (1%) Query 16 LVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAI 75 L++I+ L V++GT +G RYRV PPVLLI G+LLGL+P F V + EVVLLLFLPAI Sbjct 4 LLLIIVLGITVLIGTTVGGRYRVAPPVLLICFGALLGLLPPFSHVMLAPEVVLLLFLPAI 63 Query 76 LYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTD 135 LY ES+ TS RE+R N+ VI M ++ LV T VAVS + G++ A VLGAVL+PTD Sbjct 64 LYRESLTTSLREVRANITVIAMLAVVLVGLTMVAVSLVVQRFGIDPAVAWVLGAVLAPTD 123 Query 136 AAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSY 195 AAAVAGLAK++PRR LT L ESLINDGTALVLFAV + + G A LV R +S+ Sbjct 124 AAAVAGLAKQMPRRLLTTLHTESLINDGTALVLFAVALGLLGGGAAPNAFELVERIGLSF 183 Query 196 LGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVL 255 LGGI AGLLVG +V +R+ +D PL EGA+S+LTPFAAF LA+++ SGV+AV+V+ L+L Sbjct 184 LGGIAAGLLVGIVVIGIRKHLDDPLREGAVSVLTPFAAFFLAEAVHESGVLAVVVAGLIL 243 Query 256 TYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLA 315 Y P VIRARSR+ A +FWD+ TFLING L+V VG+QIP A+ + L RA ++A Sbjct 244 AYASPRVIRARSRVLALSFWDLTTFLINGGLFVLVGLQIPRAVSDVTSL--ALTRALLIA 301 Query 316 LAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALA 375 + V V++A R+ WV A ++ VD R V +R R V WAGFRGAVSLAAALA Sbjct 302 VVVAVVLVAVRMLWVHAMALILRLVDWRKVHLDRRVNWRVRTVAGWAGFRGAVSLAAALA 361 Query 376 VPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLART 435 VPM+ + G P P+R+LIIF V+ VIL+T+LVQGT+LP V++WAR+ D +E + A+ Sbjct 362 VPMSID-GQPVPERDLIIFCVAAVILLTMLVQGTTLPLVMKWARLTGDPDRTDEKRQAQR 420 Query 436 RSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGAD-SATSDLAERNDLVRR 494 + + L ALP +AD +G PD ++ ++ EYE + +D D +A + AE Sbjct 421 HAIRQTLHALPDLADRVGADPDTMRRIQDEYESHLDGLQSDPQDETAAAQEAEHQ----- 475 Query 495 VRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 +RL L H+R+ +T LR++ IDD V REL+A +D+EE++LL P E Sbjct 476 LRLAALDHKRREITRLRDRRQIDDAVQRELEARLDVEEIRLLGPRTLE 523 >gi|302867806|ref|YP_003836443.1| Na+/H+ antiporter [Micromonospora aurantiaca ATCC 27029] gi|302570665|gb|ADL46867.1| Na+/H+ antiporter [Micromonospora aurantiaca ATCC 27029] Length=520 Score = 430 bits (1105), Expect = 4e-118, Method: Compositional matrix adjust. Identities = 275/527 (53%), Positives = 357/527 (68%), Gaps = 8/527 (1%) Query 17 VVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAIL 76 ++I L A V+VGT +G RY V PPVLLI G+L+GL+P F ++ ++ EVVL+LFLPAIL Sbjct 1 MLITVLGATVLVGTTIGGRYSVAPPVLLIAMGALIGLLPPFENLILEPEVVLVLFLPAIL 60 Query 77 YWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDA 136 Y ES+ S REIR NL VIV ++ LVI T VAV++TA+ALG++ AA VLGAVL+PTDA Sbjct 61 YRESLVISLREIRANLTVIVGLAVVLVIVTMVAVAYTAQALGVQPAAAWVLGAVLAPTDA 120 Query 137 AAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYL 196 AAVAGLAKR+PR LT LR ESL+NDGTALVLFAV V G G L G FV Sbjct 121 AAVAGLAKRMPRGILTTLRAESLVNDGTALVLFAVAAGVVAGGTVPGALTLSGEFVGKSA 180 Query 197 GGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLT 256 GG+ AGLLVG +V L+R+ +D P+ EG LS+LTPF AFLLA ++ SGV+AV+VS L+L+ Sbjct 181 GGVAAGLLVGAVVVLIRKHVDDPMREGGLSILTPFVAFLLADAVHASGVLAVVVSGLLLS 240 Query 257 YVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATV-LA 315 Y P VIRARSR+ A AFWD++TF+ING L+V +G Q+P ++ I P A++ +A Sbjct 241 YAAPRVIRARSRVTAFAFWDLSTFMINGGLFVLLGTQVPRSLRSITSHS---PTASLGIA 297 Query 316 LAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALA 375 + V VV+A R+ WV + VDR RH R R WAGFRGAVSLAAALA Sbjct 298 VLVAAVVVAIRLLWVHLSVSALQRVDRRESSRARHFDGRMRTAVGWAGFRGAVSLAAALA 357 Query 376 VPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLART 435 VP+ + G+P +R+LIIFV VVI++ +LVQGT+LP VV WA + D E++ AR Sbjct 358 VPVAMHDGSPVRERDLIIFVTVVVIVLIMLVQGTTLPAVVSWAGLTGDRERDEEVRWARI 417 Query 436 RSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLVRRV 495 R+ +AAL+ALP A ++G D V L +YE+ +AD D D ++ RR+ Sbjct 418 RATEAALEALPRAASDVGATQDTVDRLRADYEDH----LADARDPGGEDAEAEREMARRL 473 Query 496 RLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 RL VL H+RQ +T LRN IDD VLR+LQAA+D+EE++LL P E Sbjct 474 RLRVLDHKRQEITRLRNTRQIDDAVLRQLQAAIDIEEIRLLGPEMEE 520 >gi|256378949|ref|YP_003102609.1| Na+/H+ antiporter [Actinosynnema mirum DSM 43827] gi|255923252|gb|ACU38763.1| Na+/H+ antiporter [Actinosynnema mirum DSM 43827] Length=530 Score = 350 bits (899), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 233/520 (45%), Positives = 328/520 (64%), Gaps = 5/520 (0%) Query 16 LVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAI 75 L+V+V++ AAV+ +L R R+ PP++L++ G+L L+P +++ EVVLLLFLPA+ Sbjct 7 LIVLVSVGAAVIALHLLARRLRLSPPIVLLVGGALAALVPWLEPIRLPPEVVLLLFLPAL 66 Query 76 LYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTD 135 L+WE++NTS REIR NLR I + S+ LV+ TA +V+ ALG+ A VLGAV++PTD Sbjct 67 LHWEALNTSLREIRANLRSIALSSVVLVLVTAASVAAVGHALGLSWPVAFVLGAVVAPTD 126 Query 136 AAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSY 195 A AV +A R+P R LT+LR ESL+NDGTALVLFA+ VAVA G + +G F +SY Sbjct 127 ATAVGAVAGRMPHRQLTLLRAESLVNDGTALVLFAIAVAVASGREEFSWPSALGDFGLSY 186 Query 196 LGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVL 255 GG++ GLLVG LVT LR+ + PL E +S+LTPF AFLLA+ + SGV+A +V L++ Sbjct 187 AGGVVVGLLVGLLVTWLRKVVVEPLPEAGISVLTPFTAFLLAEEVHASGVLATVVCGLLV 246 Query 256 TYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLA 315 + GP AR+RLQ+ FW + FL+NG+L+V VG+Q+ A+ D RA + Sbjct 247 SQTGPRWFSARTRLQSRGFWQLGAFLLNGALFVLVGLQLRDAV-----ADAHTWRALLAV 301 Query 316 LAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALA 375 + V+ VI R+ + L VDR + R +GFR+R +WAGFRG VSLAAALA Sbjct 302 VLVSATVIGVRLLFFNTVPYLVRLVDRRPAQRDRRMGFRERLPVAWAGFRGGVSLAAALA 361 Query 376 VPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLART 435 VP+T G FP+R L++ V VI+ T L QG +LP V+RWAR+ ED A EL LA Sbjct 362 VPLTVQDGGAFPERELLVVVTFGVIVATTLGQGLTLPLVLRWARLGEDEARPAELLLAER 421 Query 436 RSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLVRRV 495 +++A L AL A L D+V+ + E R + A G D A + D + Sbjct 422 TASEAGLAALDEAARGLDAPRDVVERVRGEIRRRLESLEAMGVDGAPVENPLLGDDYAAL 481 Query 496 RLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQL 535 L +L+ +R AV LR++ L+DD+VL +Q +D+EEV+L Sbjct 482 HLALLEPKRAAVVRLRDERLVDDLVLLRMQTRLDVEEVRL 521 >gi|331698653|ref|YP_004334892.1| Na+/H+ antiporter [Pseudonocardia dioxanivorans CB1190] gi|326953342|gb|AEA27039.1| Na+/H+ antiporter [Pseudonocardia dioxanivorans CB1190] Length=529 Score = 344 bits (883), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 233/505 (47%), Positives = 323/505 (64%), Gaps = 7/505 (1%) Query 32 LGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREIRWN 91 L RY + P +LL+L G L+G P + Q+ EVVLL+FLP +LYWES+ TS REIR N Sbjct 22 LARRYPIAPAILLVLVGVLIGFAPHLREAQLPPEVVLLVFLPVLLYWESLTTSLREIRNN 81 Query 92 LRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDAAAVAGLAKRLPRRAL 151 LRV+V+ S LV ATA AV+ A A+G+ AA VLGA L+PTDA AV LA+RLPRR + Sbjct 82 LRVVVLTSTVLVFATAAAVAAVAHAIGLAWGAAWVLGAALAPTDATAVGVLARRLPRRIV 141 Query 152 TVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLGGIMAGLLVGGLVTL 211 TVLR ESL+NDGTALV++ + V V G + + G +++Y GG++AG+LVG + Sbjct 142 TVLRAESLVNDGTALVIYGLAVGVTIGEEHLTTLHVTGLLILAYGGGLLAGVLVGLVSWQ 201 Query 212 LRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIRARSRLQA 271 LRRR+D P+ E L+TPFAAFL A+S+ SGV+AV+ L ++ V P + A +R + Sbjct 202 LRRRMDDPMLENIAMLVTPFAAFLAAESVDASGVLAVVACGLFISQVTPRITNAVTRQTS 261 Query 272 HAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLALAVTGVVIATRIAWVQ 331 FW + T +++ +L+V VG++ A+ ++ L RA V L +T VVI R AW+ Sbjct 262 VPFWTVTTTVLSSALFVLVGLEAHTAVRGLSSV--SLLRALVDILLITAVVIGVRWAWLY 319 Query 332 ATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNL 391 T + +DR + R +G RQR V+ AGFRGAVSLAA LAVP T +SGAPFPDR+L Sbjct 320 TTPYIIRALDRRPAQRLRRIGARQRTVSGVAGFRGAVSLAAILAVPQTLDSGAPFPDRDL 379 Query 392 IIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLARTRSAQAALDALPTVADE 451 I+ + S VI V L+Q LP VVR+AR+P D + A E Q A AALD++PT A E Sbjct 380 IVVITSGVI-VLTLLQALLLPRVVRFARLPPDDSVAEERQYAEMYITDAALDSIPTTASE 438 Query 452 LGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAER-NDLVRRVRLGVLQHQRQAVTTL 510 LG+ +V + E E+R ++ ADG + DL R +D + L ++ +R+A+ L Sbjct 439 LGIDERVVARVRGEIEKRRTVLAADGTE---DDLVVRHDDQYASLHLALIARKREALLEL 495 Query 511 RNQNLIDDIVLRELQAAMDLEEVQL 535 R++ IDDIVLR +QA +D+EEV+ Sbjct 496 RDEQRIDDIVLRAIQARLDIEEVRF 520 >gi|256392488|ref|YP_003114052.1| Na+/H+ antiporter [Catenulispora acidiphila DSM 44928] gi|256358714|gb|ACU72211.1| Na+/H+ antiporter [Catenulispora acidiphila DSM 44928] Length=535 Score = 341 bits (874), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 224/531 (43%), Positives = 326/531 (62%), Gaps = 11/531 (2%) Query 13 VFGLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFL 72 + L VIV + A V+ ++G+R + PPVL++ +G L+G +PR V + + VLL+FL Sbjct 1 MLALTVIVVIGACVLASGIVGNRLGIAPPVLMLAAGVLVGFVPRLRSVNLPPDTVLLVFL 60 Query 73 PAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLS 132 PA+LYWES+N S R IR +LR +V+ S LVI +A V+ A A G+ A +LG L+ Sbjct 61 PALLYWESLNASLRAIRRSLRGVVLMSTVLVIFSAAMVAVVAHAFGLPWGPAWILGGALA 120 Query 133 PTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFV 192 PTDA AVA L + LPRRA+ +L+ ESLINDGTALV++ V V+V GA + F Sbjct 121 PTDATAVAALGRVLPRRAMNLLQAESLINDGTALVVYGVAVSVTIGAEHFSTVHVGLLFA 180 Query 193 VSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSA 252 SY+GG AG+ V L +R+R++ PL E LL PF+AFLLA++++ SGV+AV+ Sbjct 181 RSYIGGAAAGIAVAFLGAKVRKRLEDPLLENVAVLLIPFSAFLLAEAIQASGVLAVVACG 240 Query 253 LVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRAT 312 L+++ +GP V RL + FW + T+L+NG+L+V VG+Q A+ ++ D L RA Sbjct 241 LIMSQLGPRVGTPAVRLLSQGFWTLGTYLLNGALFVLVGLQSQSAVRNLTSFD--LARAL 298 Query 313 VLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAA 372 AV GV+I R + A L +DR + R V R +T AGFRGAVSLAA Sbjct 299 SAVAAVCGVLIGVRFVFQFAVIYLIRALDRRASQQARRVSHGFRVITGLAGFRGAVSLAA 358 Query 373 ALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQL 432 ALAVP T ++G P PDR++I+FV + VI +++Q +LP VVRWA +PED +E ++ Sbjct 359 ALAVPNTLHNGQPLPDRDVIVFVTAGVI-AALMLQAFALPPVVRWADLPEDTVIESESRM 417 Query 433 ARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMAD--------GADSATSD 484 A +A+ AL+A+P +A LG AP++ +EYE+R + A D A Sbjct 418 ANRTAAEEALEAMPAIAATLGTAPEITDMARREYEKRLHVSQAGDPDDDSVDMDDDAAER 477 Query 485 LAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQL 535 L E + R +RL +L ++R + LR+++ IDD VLR++QA +D EEV+L Sbjct 478 LREFDSQYRELRLALLGNKRSTLLRLRDEHRIDDAVLRQIQARLDWEEVRL 528 >gi|345011916|ref|YP_004814270.1| Na+/H+ antiporter [Streptomyces violaceusniger Tu 4113] gi|344038265|gb|AEM83990.1| Na+/H+ antiporter [Streptomyces violaceusniger Tu 4113] Length=528 Score = 319 bits (817), Expect = 9e-85, Method: Compositional matrix adjust. Identities = 227/507 (45%), Positives = 303/507 (60%), Gaps = 9/507 (1%) Query 30 TVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREIR 89 T L R R PV+L+ G L+GLIP F + EVVLLLFLP +LYWES+ TS REIR Sbjct 18 TWLARRLRWNEPVMLVAGGCLIGLIPDFRGPALPPEVVLLLFLPPLLYWESLTTSLREIR 77 Query 90 WNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDAAAVAGLAKRLPRR 149 N+R IV+ + GLV+ATA AV+ ALG+ A VLGAV++PTDA AVA +A+ LPRR Sbjct 78 TNVRGIVLLATGLVLATAAAVASVGHALGLSWPLAFVLGAVVAPTDAIAVATVARGLPRR 137 Query 150 ALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLGGIMAGLLVGGLV 209 T+LR ESLINDGTAL L+AV + VA + RF+++Y GG G +V Sbjct 138 IRTILRAESLINDGTALTLYAVVIGVAVKGLSVTWTDTAVRFLLAYAGGAAIGCGCAAVV 197 Query 210 TLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIRARSRL 269 LRRR+ E AL +LTPFA +L AQ L SGV+AV+ L+L+ GP VI A SR+ Sbjct 198 VALRRRLRDRSVENALGVLTPFATYLPAQVLGVSGVLAVVTCGLILSQAGPKVISAGSRV 257 Query 270 QAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLALAVTGVVIATRIAW 329 Q +FW+++T L+N +L+V VGVQ P + I G A + A V+GVVIATR+ W Sbjct 258 QIISFWEVSTSLLNSALFVLVGVQTPAIVSGIGSVSPG--HAVITASLVSGVVIATRLLW 315 Query 330 VQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNSGAPFPDR 389 + + L +DR + T G RQR +W+G RGAVSLAAALAVP T +G P Sbjct 316 LYSVPYLIRVIDRRPVQRTLRYGARQRFPVAWSGVRGAVSLAAALAVPTATATGQPLAGH 375 Query 390 NLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLARTRSAQAALDALPTVA 449 L++F VILVT+++QGT++P V+RW+ + D E + A + AAL+ALP A Sbjct 376 GLLVFTAVTVILVTLVLQGTTMPAVIRWSGLHGDPDETAEERRAHRQIIAAALEALPDHA 435 Query 450 DELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDL-VRRVRLGVLQHQRQAVT 508 L P+ + E + A T D R L +RR +GV +R A+ Sbjct 436 RRLKTPPETADAILSELRQYAA---EKAGPPDTEDTGVRAGLELRRALIGV---ERSALI 489 Query 509 TLRNQNLIDDIVLRELQAAMDLEEVQL 535 LR+Q IDDIVLR LQ+ +D EE+++ Sbjct 490 RLRDQRSIDDIVLRRLQSLLDTEEIRI 516 >gi|302557388|ref|ZP_07309730.1| Na+/H+ antiporter [Streptomyces griseoflavus Tu4000] gi|302475006|gb|EFL38099.1| Na+/H+ antiporter [Streptomyces griseoflavus Tu4000] Length=508 Score = 318 bits (816), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 216/505 (43%), Positives = 320/505 (64%), Gaps = 17/505 (3%) Query 41 PVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSI 100 PVL + +G LG +P + ++ +V+LL+FLP +LYWES+ TS R IR +LR +V+ Sbjct 4 PVLQLTAGVALGFMPALRETELPPDVLLLVFLPVLLYWESVTTSLRAIRRDLRGVVLTGT 63 Query 101 GLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLI 160 LV TA AV+ A LG+ A VLGA ++PTDA AV +++ LP+R +T+LR ESLI Sbjct 64 LLVAVTAWAVAALAHVLGLPWGPAWVLGAAVAPTDATAVGVVSRLLPQRNVTLLRAESLI 123 Query 161 NDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRI---- 216 NDGTALV++++ V V G+ + A + G +SY GG+ AG +V L LRRR+ Sbjct 124 NDGTALVVYSLAVGVTVGSEHLSVAHVSGLVALSYGGGLAAGAVVAWLGIQLRRRVRQLG 183 Query 217 DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWD 276 D L+ + +L PF+A+L+A+ ++ SGV+AV+V L+++ GP++ RA +R Q AFW Sbjct 184 DTLLDNLTI-ILIPFSAYLVAEQIEASGVLAVVVCGLIMSQAGPSLGRAAARRQTEAFWS 242 Query 277 IATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVL 336 +A +L+NG+L+V VG++ A+ + G L A V+ +AV ++ R ++ Sbjct 243 LAMYLLNGALFVLVGLEAQAAVRALTG--NALTEAVVMVVAVACALVIVRFLFLFFAVYT 300 Query 337 GHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVV 396 +DR ++ R + R R V++ AGFRGAVSLA AL+VP T +SGAPFPDR+ I+FV Sbjct 301 IRALDRRPQQRGRRMSHRARAVSALAGFRGAVSLALALSVPYTLDSGAPFPDRDTIVFVT 360 Query 397 SVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLARTRSAQAALDALPTVADELGVAP 456 + V++ T++VQG LP V RWAR+P D +EL LART +++AALDALP A +LG Sbjct 361 AGVVVATLVVQGLVLPAVARWARLPRDTDSEHELALARTATSRAALDALPATAADLGTDA 420 Query 457 DLVKHLEKEYEERAVLVMADGADSATSDLAERNDLVRR------VRLGVLQHQRQAVTTL 510 ++V+ LE EYE V A AD+A+ E L+RR +RL +L+H+ AV L Sbjct 421 EVVEDLEAEYETHLSTVQA--ADAASD--PESEPLLRRRRQETSLRLALLEHKGSAVIAL 476 Query 511 RNQNLIDDIVLRELQAAMDLEEVQL 535 R+++ IDD VL +Q +D EEV+L Sbjct 477 RDRHRIDDAVLLRVQEQLDAEEVRL 501 >gi|311112769|ref|YP_003983991.1| CPA1 family monovalent cation:proton (H+) antiporter-1 [Rothia dentocariosa ATCC 17931] gi|310944263|gb|ADP40557.1| CPA1 family monovalent cation:proton (H+) antiporter-1 [Rothia dentocariosa ATCC 17931] Length=546 Score = 302 bits (774), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 200/553 (37%), Positives = 309/553 (56%), Gaps = 34/553 (6%) Query 16 LVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIP-----RFGDVQIDGEVVLLL 70 L VI+AL A+++G +L H+ R+ P ++LI G +L LIP + + V+L + Sbjct 2 LEVIIALSLAILLGNILAHKIRITPAIMLIFMGLVLALIPVHAMHEVREAGLPPHVILEI 61 Query 71 FLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARA-LGMES-HAAAVLG 128 FLP +L+WE+ NTS+RE+R LR I++ LVI TA ++W +G+ H A ++G Sbjct 62 FLPVMLFWETRNTSWREVRARLRGILLSGTVLVIFTAFVIAWVLHTFMGIYMWHVALIIG 121 Query 129 AVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA-GIGPAAL 187 L+PTDA AVA L +LP+ ++T L+ E+LINDGT LVLFA+ + +A G +G A+ Sbjct 122 VALAPTDAVAVATLNGKLPKSSITTLKAEALINDGTTLVLFALALQLAGGHELTLGNAS- 180 Query 188 VGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQS------LK 241 G F S+L G +AGL VG LR + +P+ PF AF L++ +K Sbjct 181 -GMFFFSFLIGTLAGLAVGWGANKLRAYMGSPMNFSVFMFTIPFIAFFLSEEIEPFEGMK 239 Query 242 CSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHI 301 SGVVAV+V+A LTY GP I+ ++R W ++++NG+L+V VGVQ+P A +H+ Sbjct 240 GSGVVAVVVAAFYLTYRGPDTIKPQNRFYGLPIWSFVSYIMNGALFVLVGVQLPSATEHM 299 Query 302 AGEDGGLPRATVLALAVTGVV----IATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRC 357 G A V AL V V IA R ++ T + +DR K+ FR R Sbjct 300 EGVIHEYNYAWVSALVVIVVAWLVSIAARFIFLHVTIGIIRALDRSEKQRLLRTTFRGRV 359 Query 358 VTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRW 417 V+++AG RG VSLA AL+VP R+ IIF+V+ V+L++++VQG LP V+RW Sbjct 360 VSTFAGLRGGVSLAVALSVPNDVVG------RDFIIFIVAGVVLLSMVVQGMLLPLVIRW 413 Query 418 ARMPEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVL----- 472 A P D + +E+ A + D++ V E+G + +++ + +E A + Sbjct 414 ANFPVDTSEEDEINEAIRTIIAESFDSVAEVGQEIGASQEIIDRVAEEQMYNASMYRNLH 473 Query 473 -VMADGADSATS--DLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMD 529 + GA++ + E DL + +RL L+ QR + LRN+ ID VL +Q +D Sbjct 474 TIRKHGANAPEEARRIIEAGDLEKELRLRHLEKQRSVLKRLRNERTIDMNVLHAIQEILD 533 Query 530 LEEVQLLDPADAE 542 +EE+++L P + E Sbjct 534 IEEIRVLGPVELE 546 >gi|283458893|ref|YP_003363540.1| NhaP-type Na+/H+ and K+/H+ antiporter [Rothia mucilaginosa DY-18] gi|283134955|dbj|BAI65720.1| NhaP-type Na+/H+ and K+/H+ antiporter [Rothia mucilaginosa DY-18] Length=546 Score = 300 bits (767), Expect = 5e-79, Method: Compositional matrix adjust. Identities = 204/553 (37%), Positives = 308/553 (56%), Gaps = 34/553 (6%) Query 16 LVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIP-----RFGDVQIDGEVVLLL 70 L VI+AL A+++G +L H+ R+ P +LLI G +L LIP +V + V+L + Sbjct 2 LEVIIALSLAILLGNILAHKIRITPAILLIFLGLVLALIPVHAMHEVREVGLPPHVILEI 61 Query 71 FLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARA-LGME-SHAAAVLG 128 FLP +L+WE+ NTS+RE R LR I++ LVI TA ++W +G+ H A ++G Sbjct 62 FLPVMLFWETRNTSWREARARLRGILLSGTVLVIFTAFVIAWVLHTFMGVYLWHVALIIG 121 Query 129 AVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA-GIGPAAL 187 L+PTDA AVA L +LP+ ++T L+ E+LINDGT LVLFA+ + +A G +G A+ Sbjct 122 VALAPTDAVAVATLNGKLPKSSITTLKAEALINDGTTLVLFALALQLAGGHELTLGTAS- 180 Query 188 VGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQS------LK 241 G F S+L G + GL VG V LR I P+ PF AF LA+ +K Sbjct 181 -GMFFFSFLIGTLVGLAVGWGVDKLRAHIGNPMNFSVFMFTVPFIAFFLAEEIEPFEGMK 239 Query 242 CSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGA---I 298 SGVVAV+V+A LTY GP I+ ++R W ++++NG+L+V VGVQ+P A + Sbjct 240 GSGVVAVVVAAFYLTYRGPDTIKPQNRFYGLPIWSFVSYVMNGALFVLVGVQLPSATAPV 299 Query 299 DHIAGEDGGLPRATVLALAVTGVV-IATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRC 357 D + E T + V +V IA R ++ + + +DR K+ FR R Sbjct 300 DDVLREYNYAWALTFAVIVVAWLVSIAARFIFLHVSIGIIRALDRSEKRKQLRTTFRGRV 359 Query 358 VTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRW 417 V+++AG RG VSLA AL+VP P R+ IIFVV+ V+L++++VQG LP V+RW Sbjct 360 VSTFAGLRGGVSLAVALSVPTDV------PARDFIIFVVAGVVLLSMVVQGMLLPLVIRW 413 Query 418 ARMPEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVL----- 472 A++P D +E+ A + D++ + E+G ++ + E A + Sbjct 414 AKIPVDTTEEDEINEAIRTIIAESFDSVAEIGQEIGAPQWIIDRIADEQMYNASIHRNLH 473 Query 473 -VMADGADSATS--DLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMD 529 V DGA++ + E DL + +RL L+ QR + LRN+ +ID VL +Q +D Sbjct 474 AVRKDGANAPEEARRIIEAGDLEKELRLRHLEKQRSVLKRLRNERIIDTNVLHVIQEILD 533 Query 530 LEEVQLLDPADAE 542 +EEV++L P + E Sbjct 534 IEEVRVLGPVELE 546 >gi|300744178|ref|ZP_07073197.1| Na+/H+ antiporter [Rothia dentocariosa M567] gi|300379903|gb|EFJ76467.1| Na+/H+ antiporter [Rothia dentocariosa M567] Length=546 Score = 297 bits (760), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 199/553 (36%), Positives = 307/553 (56%), Gaps = 34/553 (6%) Query 16 LVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIP-----RFGDVQIDGEVVLLL 70 L VI+AL A+++G +L H+ R+ P ++LI G +L LIP +V + V+L + Sbjct 2 LEVIIALSLAILLGNILAHKIRITPAIMLIFMGLVLALIPVHAMHEVREVGLPPHVILEI 61 Query 71 FLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARA-LGMES-HAAAVLG 128 FLP +L+WE+ NTS+RE+R LR I++ LVI TA ++W +G+ H A ++G Sbjct 62 FLPVMLFWETRNTSWREVRARLRGILLSGTVLVIFTAFVIAWVLHTFMGVYMWHVALIIG 121 Query 129 AVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAA-GIGPAAL 187 L+PTDA AVA L +LP+ ++T L+ E+LINDGT LVLFA+ + +A G +G A+ Sbjct 122 VALAPTDAVAVATLNGKLPKASITTLKAEALINDGTTLVLFALALQLAGGHELALGNAS- 180 Query 188 VGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQS------LK 241 G F S+L G + GL VG LR I P+ PF AF L++ +K Sbjct 181 -GMFFFSFLIGTLVGLAVGWGANKLRAHIGNPMNFSVFMFTIPFIAFFLSEEIEPFEGMK 239 Query 242 CSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHI 301 SGVVAV+V+A LTY GP I+ ++R W ++++NG+L+V VGVQ+P A +H+ Sbjct 240 GSGVVAVVVAAFYLTYRGPDTIKPQNRFYGLPIWSFVSYVMNGALFVLVGVQLPSATEHM 299 Query 302 AG--EDGGLPRATVLALAVTG--VVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRC 357 + A+ LA+ V V IA R ++ T + +DR K+ FR R Sbjct 300 DDVVHEYNYAWASALAVIVVAWLVSIAARFIFLHVTIGIIRALDRSEKQRRLRTTFRGRV 359 Query 358 VTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRW 417 V+++AG RG VSLA AL+VP R+ IIF+V+ V+L++++VQG LP V+RW Sbjct 360 VSTFAGLRGGVSLAVALSVPTGVLG------RDFIIFIVAGVVLLSMVVQGMLLPLVIRW 413 Query 418 ARMPEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVL----- 472 A++P D +E+ A + D++ + E+G ++ + E A + Sbjct 414 AKIPVDTTEEDEINEAVRTIIAESFDSVAEIGQEIGAPQWIIDRIADEQMYNASMYRNLH 473 Query 473 -VMADGADSATS--DLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMD 529 V GA++ + E +DL + +RL L+ QR + LRN+ ID VL +Q +D Sbjct 474 AVRKHGANAPEEARRIIEASDLEKELRLRHLEKQRSVLKRLRNERTIDTNVLHAIQEILD 533 Query 530 LEEVQLLDPADAE 542 +EE ++L P + E Sbjct 534 IEEARVLGPVELE 546 >gi|269218631|ref|ZP_06162485.1| Na+/H+ antiporter [Actinomyces sp. oral taxon 848 str. F0332] gi|269211742|gb|EEZ78082.1| Na+/H+ antiporter [Actinomyces sp. oral taxon 848 str. F0332] Length=541 Score = 291 bits (746), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 199/546 (37%), Positives = 303/546 (56%), Gaps = 29/546 (5%) Query 16 LVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIP--RFGDVQIDG---EVVLLL 70 L VIVA+ AA+ +G VL +R V P +LLI G L L+P + DV+ G V+L + Sbjct 2 LEVIVAVAAAIFLGNVLAYRLGVPPAILLIFLGLALALVPAHQLNDVRELGLPPHVILEI 61 Query 71 FLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARAL-GMESHAAA-VLG 128 FLP +L+WE+ NTS+RE+R LR I++ LV+ TA AV+W + G+ S A ++G Sbjct 62 FLPVMLFWETRNTSWREVRTRLRGILLTGTALVVFTAFAVAWVLHSFVGVYSWPVALIIG 121 Query 129 AVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALV 188 A L+PTDA AVA L +LP+ A+T L+ E+LINDGT LVLFA+ + +A G A + Sbjct 122 AALAPTDAVAVATLNGKLPKSAITTLKAEALINDGTTLVLFALALQLAGGRA-LSATHAS 180 Query 189 GRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLA------QSLKC 242 G F+ S+L G + GL VG LR I +P+ PFAAFL++ Q +K Sbjct 181 GMFLFSFLIGALVGLAVGWAANALRAYIKSPMNFSVFMFTVPFAAFLISENIEPFQDMKG 240 Query 243 SGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIA 302 SGVVAV+V+A LTY GP I+ +R W ++L+NG+L+V VGVQ+P A+ + Sbjct 241 SGVVAVVVAAFYLTYRGPDTIKPVNRFYGLPIWSFVSYLMNGALFVLVGVQLPSAVKRM- 299 Query 303 GE-----DGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRC 357 GE D + A V + R +V + +DR ++ FR R Sbjct 300 GETIERFDSSWGYGLKVVAAAWAVSVLARFVFVHVVIGIIRALDRSERQRRLRTTFRGRV 359 Query 358 VTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRW 417 V+++AG RG VSLA AL+VP T R+ IFVV V++++++VQG LP V+RW Sbjct 360 VSTFAGLRGGVSLAVALSVPSGTFG------RDFTIFVVGGVVMLSMVVQGLLLPAVIRW 413 Query 418 ARMPEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADG 477 A++P D + E+ A ++ +AL +A +G + + + + E+ + + Sbjct 414 AKIPPDTSEKEEIHCAMNAISREGYEALDDIAARVGASQEAIDGAKAEWSRFQKGLEEEA 473 Query 478 ADSATSDLAERNDLVRR---VRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQ 534 + DL + R+ +RL V+ +QR+ + LRN+ ID VL +Q +D EE++ Sbjct 474 NARSNPDLDDSQSYWRQNRALRLAVIDYQREVLKRLRNEGKIDMNVLHIVQERLDTEEIR 533 Query 535 LLDPAD 540 ++ P + Sbjct 534 VIGPVE 539 >gi|323356615|ref|YP_004223011.1| NhaP-type Na+/H+ and K+/H+ antiporters [Microbacterium testaceum StLB037] gi|323272986|dbj|BAJ73131.1| NhaP-type Na+/H+ and K+/H+ antiporters [Microbacterium testaceum StLB037] Length=586 Score = 283 bits (724), Expect = 5e-74, Method: Compositional matrix adjust. Identities = 211/582 (37%), Positives = 314/582 (54%), Gaps = 69/582 (11%) Query 15 GLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPA 74 GL V V L A++VGTVL R RV P++L++ G LG IP +++ E VLLLFLP Sbjct 3 GLEVTVLLGLAMLVGTVLAPRLRVATPLVLLVIGLALGFIPELRAIELPPETVLLLFLPV 62 Query 75 ILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPT 134 +L+ E+ TS R +R +LR IV S LV+A+A AV+ A +G+ AA V+GA ++P Sbjct 63 MLFREAWTTSMRSVRRSLRYIVPMSTLLVVASAFAVAGVATWMGVPWEAALVIGAAVAPP 122 Query 135 DAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVS 194 DA AVA L + LP + L+ ESL NDGTALVL+A+ V++ G + P ++ G ++S Sbjct 123 DATAVAALGRLLPAKTFMKLKAESLTNDGTALVLYAIAVSLLLGGQ-VTPWSITGMVLLS 181 Query 195 YLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALV 254 YLGG AG+ V L RR+ + L LL PF +FLLA+ + SGV+AV+ + L+ Sbjct 182 YLGGAAAGIAVAALAYFALRRMQSTLTINLTMLLVPFVSFLLAEVIHASGVLAVVFAGLI 241 Query 255 LTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVL 314 + +V P + A SR A A W +L+NG+L+V +G+++ + I+ + G+ + Sbjct 242 VAWVSPRITTAMSRRAADATWPFGVYLLNGALFVLIGLEVQLVLHEISPSEIGMLSLITV 301 Query 315 ALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAAL 374 A + ++ W L R TR + R R V++ AGFRGAVSLA AL Sbjct 302 AAWIALFLVRYLFQW------LFSPFSRPPAGSTRSLRHRSRLVSTVAGFRGAVSLAIAL 355 Query 375 AVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLAR 434 +VP+TT+SGAP R+ ++FV + VI++T+LVQG LP V+RWA++P D A E +LA Sbjct 356 SVPITTDSGAPVAGRDSVVFVTAGVIVLTLLVQGPLLPVVIRWAKLPNDDAAIEEYELAE 415 Query 435 TRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMA------------------- 475 + AAL AL +A E G++ + +E ER L A Sbjct 416 RAISGAALAALDDLAVEHGISDRVRDRARREGYERLELANARAVARQRAIEERDLAELDA 475 Query 476 ----------DGADSATS----------------------------DLAERNDLVR---- 493 DG+ S+T D+ +R+ LVR Sbjct 476 SLDSSLDDESDGSASSTMGPVPPAGIDDEGRQSSGGLEMIAVSDDIDVTQRSPLVRHKEA 535 Query 494 -RVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQ 534 R+RL +L +R+ + LR + IDD+V R++ A +DLEE++ Sbjct 536 TRLRLAILDRKREVLLRLRREGTIDDLVARKILANLDLEEIR 577 >gi|255327461|ref|ZP_05368531.1| Na+/H+ antiporter [Rothia mucilaginosa ATCC 25296] gi|255295494|gb|EET74841.1| Na+/H+ antiporter [Rothia mucilaginosa ATCC 25296] Length=546 Score = 275 bits (703), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 195/553 (36%), Positives = 304/553 (55%), Gaps = 34/553 (6%) Query 16 LVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIP--RFGDVQIDG---EVVLLL 70 L V++AL AV++G V+ H+ R+ P ++LI G +G++P +VQ G V+L + Sbjct 2 LEVVIALSLAVLIGNVIAHKTRITPAIVLIFIGLAIGIMPAHELHEVQSIGLPPHVILEI 61 Query 71 FLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARAL-GMESHAAAVL-G 128 FLP +L+WE+ +TS+RE R +R +++ LVI TA V+ L G+ + AA+L G Sbjct 62 FLPIMLFWEARHTSWREARNRIRGVILTGTLLVIVTAFGVAGILHELIGVSAWGAALLIG 121 Query 129 AVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALV 188 L+PTDA AVA L +LP+ ++T L+ E+LINDGT LVL + + VA G G+ Sbjct 122 VALAPTDAVAVATLNGKLPKSSITTLKAEALINDGTTLVLLTLALQVAAG-QGLSLGHSS 180 Query 189 GRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQS------LKC 242 G F S+L GI+ GL VG + +R ID P+ L PF AFLLA+ +K Sbjct 181 GMFFFSFLIGILVGLAVGWVANKIRAHIDNPMWFTCFMLTVPFIAFLLAEKIEPFPDMKG 240 Query 243 SGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIA 302 SGVVAV+++A LTY P I+ ++R W TF++N L+V VGVQ+P A++ + Sbjct 241 SGVVAVVIAAFFLTYYSPDTIKPQNRTYGLPTWAFVTFVMNAVLFVMVGVQLPTAVERMG 300 Query 303 ---GEDGGLPRATVLALAVTGV-VIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCV 358 G +L + V + +A R ++QA+ +DR K+ T R R V Sbjct 301 VTINLYGTTWSYGLLVVLVAWIACVAIRYVFLQASIFTIRLLDRSEKQRTLRTTHRGRVV 360 Query 359 TSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWA 418 ++ AG RG VSLA AL++P A R+ +IFVVS V+L +++VQG LP V+RWA Sbjct 361 STMAGLRGGVSLAVALSIP------ASVEYRDFVIFVVSGVVLCSMVVQGMMLPAVIRWA 414 Query 419 RMPEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKE-------YEERAV 471 +P D + E+ A + D++ + + +++ + +E Y Sbjct 415 NLPVDNSEEEEMNEAIRTLIAESFDSIQEIGGRINAPQEVIDRIAEEHMFNMSMYRNLHT 474 Query 472 LVMADGADSATSDLA--ERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMD 529 L M G D+ + L E ++ + +RLGVL+ QR + LR++ ID VL ++Q +D Sbjct 475 LHM-HGDDTPENVLKVLEAHEKEKELRLGVLEVQRDILKRLRDEGRIDTNVLHQIQERLD 533 Query 530 LEEVQLLDPADAE 542 +E +++L P + E Sbjct 534 IEVMRVLGPLELE 546 >gi|311899714|dbj|BAJ32122.1| putative sodium/proton antiporter [Kitasatospora setae KM-6054] Length=528 Score = 275 bits (702), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 220/505 (44%), Positives = 305/505 (61%), Gaps = 4/505 (0%) Query 35 RYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREIRWNLRV 94 RYRV PVL + +G LLG +P V++ EVVLLLFLP +LYWE+M +S +EIR NLR Sbjct 23 RYRVAAPVLQLGAGVLLGFVPALRAVELPPEVVLLLFLPVLLYWEAMTSSLQEIRRNLRG 82 Query 95 IVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVL 154 IV+ S LV+ TA AV+ A+G+ A VLG ++PTDA AV +A+ LPRR L VL Sbjct 83 IVLMSTALVVLTAGAVAAAVHAMGVPWGPAWVLGGAVAPTDATAVGVVARLLPRRNLMVL 142 Query 155 RGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRR 214 + ESL+NDGTALV++ + V V G +G + F +SY GG+ AG+L L ++RR Sbjct 143 KAESLVNDGTALVVYGLAVGVTVGEDRVGVLHVSWLFALSYAGGVAAGVLTAWLGVVVRR 202 Query 215 RIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAF 274 R+ PL + LL PF+ +LLA+S+ SGV+AV+ + L+++ PTV A +R Q A Sbjct 203 RVSDPLAANLVFLLIPFSGYLLAESVGASGVLAVVAAGLIISQTSPTVGSAEARRQIVAS 262 Query 275 WDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLALAVTGVVIATRIAWVQATT 334 W + TFL+NG+L+V VG++ GA+ + A + + V V+ TRIA++ A+ Sbjct 263 WSLGTFLLNGALFVLVGIEAQGAVRGLTATSVAR--ALAMVVVVAVVLSGTRIAFLFASA 320 Query 335 VLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIF 394 L VDR ++ R V R R V+ AGFRGAVSLAAALAVP T +SG PFPDR+LI+F Sbjct 321 YLIRAVDRRPQQRERRVSGRARIVSGLAGFRGAVSLAAALAVPATLDSGEPFPDRDLIVF 380 Query 395 VVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLARTRSAQAALDALPTVADELGV 454 V VI+VT L+ G LP VVRWAR+P+ A E +LA + AL ALP A E G Sbjct 381 VTFGVIVVT-LLHGLVLPGVVRWARLPDPAADGAEERLAHETLLRTALAALPEAAAEAGA 439 Query 455 APDLVKHLEKEYEERAVLVMADGADSATSDLA-ERNDLVRRVRLGVLQHQRQAVTTLRNQ 513 +LV +E E + A + A ER+ + L ++ +R A+ LR + Sbjct 440 DGELVDRYRRELEGALADLAAADGADGAAPGAFERDPRDTALHLALIARKRAALVRLRAE 499 Query 514 NLIDDIVLRELQAAMDLEEVQLLDP 538 IDD VL L+ +D+EE++L P Sbjct 500 RRIDDTVLVSLETRLDIEELRLTHP 524 >gi|297163002|gb|ADI12714.1| Na+/H+ antiporter [Streptomyces bingchenggensis BCW-1] Length=540 Score = 268 bits (686), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 210/484 (44%), Positives = 289/484 (60%), Gaps = 6/484 (1%) Query 54 IPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWT 113 +PRFG+V + +VVLLLFLPA+LYWES+ TS REI+ N R I + + GLV+ TAVAV+ Sbjct 42 MPRFGNVHLPPDVVLLLFLPALLYWESLTTSLREIKNNFRSIALQATGLVLVTAVAVALV 101 Query 114 ARALGMESHAAAVLGAVLSPTDAAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTV 173 A ALG A VLGAVL+PTD AAVA +A +PRR LT+LR ESL+NDGTALVL AV + Sbjct 102 AHALGYGWPIAFVLGAVLAPTDVAAVAAVAMAMPRRILTLLRTESLLNDGTALVLLAVGL 161 Query 174 AVAEGAAGIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAA 233 + RFV +Y GG G + L+ +RR + + LS+ TPF A Sbjct 162 ELLTTGEPFSWTHTAVRFVEAYAGGAAIGAAIALLLIPVRRHLRDRVLHSGLSVATPFIA 221 Query 234 FLLAQSLKCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQ 293 +L A++L SGV+AV+ LV + VGP VI + +R+QA +FW++ TFL+NG+L+V VG++ Sbjct 222 YLPAEALHVSGVLAVVTCGLVTSRVGPKVIGSDARMQATSFWEVTTFLLNGALFVLVGIE 281 Query 294 IPGAIDHIAGEDGGLPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGF 353 P AI + L +A V+A V+ VIA R+AW L VDR ++ R + Sbjct 282 TPAAIRSLTSI--SLLQAAVIAAVVSATVIAARVAWFYTIPYLVRLVDRRPRQRERRISA 339 Query 354 RQRCVTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPT 413 RQR +WAG RGA+SLAAAL +P TT G P R+ +IF+ VVI VT+ + G +LP Sbjct 340 RQRLPLAWAGMRGAISLAAALTIPTTTVDGRPLEQRDAVIFITVVVITVTLALLGPALPA 399 Query 414 VVRWARMPEDVAHANELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLV 473 VVRWAR +D+ A E LA A AA +P +A+ L V + KE +++ + Sbjct 400 VVRWARFDDDIGDAAEEALAVRHLASAARAEMPALAERLDVPRAATALIAKELDKQ--IA 457 Query 474 MADGADSATSDLAERNDL--VRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLE 531 M G A R L V + +L +R A+ LR Q+ +DDIVL +Q +D E Sbjct 458 MGSGMTHDEEGHASRRQLSAVHALEAALLDIKRAALGDLRRQSRVDDIVLLRVQRYLDAE 517 Query 532 EVQL 535 + +L Sbjct 518 QYRL 521 >gi|338209568|ref|YP_004653615.1| Na+/H+ antiporter [Runella slithyformis DSM 19594] gi|336303381|gb|AEI46483.1| Na+/H+ antiporter [Runella slithyformis DSM 19594] Length=541 Score = 265 bits (678), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 171/517 (34%), Positives = 282/517 (55%), Gaps = 16/517 (3%) Query 31 VLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREI-R 89 +LG + R+ P+ L++ G L+ IP I +++ L+FLP +LY + TS+ + + Sbjct 30 MLGQKLRISYPIFLVIGGLLISFIPSIPAFSISPDLIFLIFLPPLLYEAAWYTSWSDFWK 89 Query 90 WNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPTDAAAVAGLAK--R 145 W R I + GLVI T+ +++ A + G +LG ++SP DA A + K + Sbjct 90 WK-RPIALLGFGLVIFTSCIIAFVANSFIPGFTLALGFLLGGIISPPDAVAATSILKSVK 148 Query 146 LPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLGGIMAGLLV 205 +PRRAL VL+GESL+ND +L++F +A + A F V+ L GI+ GLLV Sbjct 149 VPRRALVVLQGESLVNDAASLIVFRFALAAVISGTFVLEKAATDFFAVT-LMGIVVGLLV 207 Query 206 GGLVTLLRRRIDAPLE-EGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIR 264 L+ R + + AL+ + P+ ++ A+ SGV+AV+ L L+Y Sbjct 208 AHFFYLIHRWLPTNASIDTALTFMGPYFMYIGAEHFHYSGVMAVVSGGLFLSYRSHEFFG 267 Query 265 ARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLALAVTGVVIA 324 RSRLQ+ + W TF++NG +++ +G+Q+P I H G + L A L ++ V IA Sbjct 268 YRSRLQSQSVWKTVTFVLNGLVFILIGLQLP-VIVHSLG-NYSLFEALKYGLFISTVTIA 325 Query 325 TRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNSGA 384 RI W+ T L + ++ G++ V SWAG RG VSLA+ALA+P+T G Sbjct 326 IRILWMYPATYLPRMFSKRIRANEEDPGWKGVFVVSWAGMRGVVSLASALAIPVTLAGGQ 385 Query 385 PFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPE-DVAHANELQLA--RTRSAQAA 441 FP RNLI+F+ VVILVT++ QG +LP ++RW ++ E D +E Q A + R QAA Sbjct 386 VFPQRNLILFITFVVILVTLVFQGLTLPLILRWLKIEEADSTLPDEEQEAGVKLRLLQAA 445 Query 442 LDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERND--LVRRVRLGV 499 L L + + +LV +L+K+ E L ++ +S D ++++ + RV + Sbjct 446 LTRLNDLYTKETTENELVDNLKKQLENDISLT-SEKLNSLECDEVDKSEVAVFNRVVHDI 504 Query 500 LQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLL 536 + +R+ + LR + + D+ +LR +A +DL+E +++ Sbjct 505 ISARRKELFLLRKEKIFDEEILRHEEAQLDLDEAKII 541 >gi|196230022|ref|ZP_03128885.1| Na+/H+ antiporter [Chthoniobacter flavus Ellin428] gi|196225619|gb|EDY20126.1| Na+/H+ antiporter [Chthoniobacter flavus Ellin428] Length=538 Score = 265 bits (676), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 185/511 (37%), Positives = 281/511 (55%), Gaps = 18/511 (3%) Query 41 PVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSI 100 PVL++L G LGLIPR E+VL +F+P +L+ + TS+ + ++NLR I + ++ Sbjct 29 PVLMVLCGLSLGLIPRLPHFTFPPELVLPVFIPPLLFPAAFLTSWHDFKFNLRPIFLLAV 88 Query 101 GLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPTDAAAVAGLAKRL--PRRALTVLRG 156 GLV+ T + V+WTA A G+ AA VLGA++SP DA A + +RL PRR +TVL G Sbjct 89 GLVLLTMLTVAWTAHACIPGLPWSAAFVLGAIISPPDAIAATAVFERLEVPRRIVTVLEG 148 Query 157 ESLINDGTALVL--FAVTVAVAEGAAGIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRR 214 ESL+ND ALV FA+T AV G + AAL V I + V V L+R Sbjct 149 ESLVNDTVALVAYRFAIT-AVVTGTFSLSTAALEVPLVALGGAIIGGLIGV--GVDWLQR 205 Query 215 RIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAF 274 R+D P + +SLLTPF A+L A+ + CSGV+A++ + + L + P ++ AR+RL+ AF Sbjct 206 RLDDPPVQVTISLLTPFLAYLTAEQVGCSGVLAIVTAGVFLGWRLPRMVTARTRLELGAF 265 Query 275 WDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLALAVTGVVIATRIAWVQATT 334 W + +L+NG ++VF+G+Q+P + + R AV V + R+ W+ Sbjct 266 WQMLVYLLNGIVFVFIGLQLPQVTQGLE-QHTSWSRLLSQTGAVCAVTVVVRLLWIYPAA 324 Query 335 VLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIF 394 L + L+ + +R + W+G RG SLA ALA+P T +GAPFP RN+IIF Sbjct 325 YLPRLLSSSLRARDPYPDWRDVTIIGWSGMRGVDSLATALALPFFTVTGAPFPGRNIIIF 384 Query 395 VVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLARTRSAQAALDALPTVADELGV 454 + VIL T++ QG SLP ++R + D E +AR + QAAL L +A+ Sbjct 385 ISFAVILFTLVAQGLSLPILIRLLGVKGDGKADCEEHVARLAANQAALAYLEGLAETKAE 444 Query 455 APDLVKHLEKEYEERAVLVMADGADSA--TSDLAERNDL------VRRVRLGVLQHQRQA 506 + L+ EY ER + + + SD+ E D ++ LQ +R A Sbjct 445 HRQQITLLQAEYHERLAQLELEEEEDEENNSDVTEERDTPTPISPFFQLARAALQIERDA 504 Query 507 VTTLRNQNLIDDIVLRELQAAMDLEEVQLLD 537 + LRNQ+ I+D LR +Q +DL + ++++ Sbjct 505 IIGLRNQHRINDETLRVVQRDIDLADARMVE 535 >gi|223939001|ref|ZP_03630886.1| Na+/H+ antiporter [bacterium Ellin514] gi|223892297|gb|EEF58773.1| Na+/H+ antiporter [bacterium Ellin514] Length=531 Score = 264 bits (675), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 190/517 (37%), Positives = 296/517 (58%), Gaps = 21/517 (4%) Query 30 TVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREIR 89 TVL + +V P+L ++ G LL LIP V++ ++V LFLP +L+ ++ TS+R+ Sbjct 18 TVLARKIKVPFPILFVIGGLLLALIPGLPRVKLRPDLVFFLFLPPLLFPAALFTSWRDFY 77 Query 90 WNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPTDAAAVAGLAKRL- 146 N+R I + ++GLVI T V V + A L G+ AA GA++SP DA A +A+RL Sbjct 78 ANIRSISLLAVGLVIFTTVVVGFLAHYLVEGLPLGAAFAFGAIVSPPDAVAATAIAQRLG 137 Query 147 -PRRALTVLRGESLINDGTALVLFAVTVA-VAEGAAGIGPAALVGRFVVSYLGGIMAGLL 204 PRR +TVL GESL+ND +ALV VA + G+ + A G FV+ +GGI GL Sbjct 138 MPRRIVTVLEGESLVNDASALVALRFAVAAMVSGSFSLVQAG--GAFVLVSMGGIAIGLG 195 Query 205 VGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIR 264 +G + + + ID P + +SLLTPFAA+L A+ L SGV+ V+ + L + + P + Sbjct 196 IGWVSVKISKWIDDPPVQIIISLLTPFAAYLSAERLGVSGVLGVVTAGLYVGWHMPEISD 255 Query 265 ARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGED--GGLPRATVLALAVTGVV 322 A++RL A+ FW++ FL+NG +++ +G+Q+P + + G+ +A +L+LAV Sbjct 256 AKTRLLAYPFWEMVVFLLNGIIFLLIGLQLPEVLQTLEGQSMLKLCGQAALLSLAV---- 311 Query 323 IATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNS 382 I RI WV T L + L++ + G+R + +W G RG VSLAAAL +P T + Sbjct 312 ILVRIVWVFPATYLPRYFSQALRQRDPYPGWRNVSIVAWTGMRGVVSLAAALGLPFTLAN 371 Query 383 GAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLARTRSAQAAL 442 G PFP R+ IIF VI+ T++ QG +LP ++R ++ D E + AR ++ QAA+ Sbjct 372 GKPFPGRDSIIFFTFCVIVATLVFQGLTLPALIRALKVSSDNLAEQEEREARLKANQAAM 431 Query 443 DALPTVADELGVAPDLVKHLEKEYEER----AVLVMADGADSATSDLAERNDLVRRVRLG 498 L + E V +LV L +EYE+R V + + TS L+ R++ Sbjct 432 TRLKELGKEDSVPNELVDRLHREYEDRIKELHVCSLEAPEERPTSGLSP----YLRLQDE 487 Query 499 VLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQL 535 L+ +RQ + LRNQ +I+D V+R ++ +DL E +L Sbjct 488 ALKVERQVILNLRNQRVINDEVMRRIERDLDLAETRL 524 >gi|343522708|ref|ZP_08759674.1| Na+/H+ antiporter [Actinomyces sp. oral taxon 175 str. F0384] gi|343402117|gb|EGV14623.1| Na+/H+ antiporter [Actinomyces sp. oral taxon 175 str. F0384] Length=534 Score = 263 bits (672), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 184/536 (35%), Positives = 290/536 (55%), Gaps = 17/536 (3%) Query 18 VIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILY 77 +IVAL+ A VV + +R+R+ PVLLI SG + L+P ++ + VVL +FLP +LY Sbjct 5 MIVALIGASVVAYAIANRFRLIAPVLLIASGVGIALLPVGEEMSLPSAVVLTIFLPILLY 64 Query 78 WESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDAA 137 WES++ S +R +LR I++ + LV TA ++ G+ AA ++GA L PTDA Sbjct 65 WESLSVSLNRMRRSLRGIILSATVLVAITAALITLIGVLTGLSVGAALLIGACLGPTDAT 124 Query 138 AVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLG 197 AV+ L + + T+L+ ESL+NDGTALV+FA+ + A+ ++G+ + + ++S+ G Sbjct 125 AVSSLGRGINPNGRTILQAESLLNDGTALVIFAIALQAAQDSSGVTAGLVAHQLLLSFGG 184 Query 198 GIMAGLLVGGLVTLLRRRI----DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSAL 253 GI AG+LVG VT + R+ D P+ +L TPF F LA+ + SGV+AV+ + Sbjct 185 GIGAGVLVGAAVTKIGIRVRTITDDPMLATITALATPFVTFFLAEEIGGSGVLAVVTCGI 244 Query 254 VLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATV 313 V++ + SR+ FW I T ++N L+V VGV +PG + + D L R + Sbjct 245 VISRFAAPHMSLGSRVLGIPFWTILTHILNTILFVMVGVALPGIVAELPHAD--LVRGLI 302 Query 314 LALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAA 373 L + ++A R A +DR ++ R FR R V++ AGFRGA+SLA A Sbjct 303 LIPIIYIAMVAGRFAGQHLIIYSIRALDRRPEQRLRRTNFRGRVVSTVAGFRGAISLAMA 362 Query 374 LAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM-PEDVAHANELQL 432 L++P++ + GA + +RNLII VV+ L+++L+QG +LP VVRWA P E Sbjct 363 LSIPVSFD-GAAYAERNLIILVVAGATLLSLLIQGLALPYVVRWANARPSAGTQTAESVE 421 Query 433 ARTRSAQA-----ALDALPTVADELGVAPD-LVKHLEKEYEERAVLVMADGADSATSDLA 486 ++ A A A+ L +A+ GV D ++ + +Y R V+ +S Sbjct 422 SQETEALAEILADAISQLDAIAERAGVDDDAAIEAVRADYARRHQSVLNSATESEADVYC 481 Query 487 ERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 +RL V++H R+ V LR IDD + +D+E + + P D E Sbjct 482 GPES---ALRLAVIEHLRERVHGLRFSGRIDDSTASRVNRRLDVETLHINGPIDVE 534 >gi|134101314|ref|YP_001106975.1| sodium/hydrogen antiporter [Saccharopolyspora erythraea NRRL 2338] gi|291008148|ref|ZP_06566121.1| sodium/hydrogen antiporter [Saccharopolyspora erythraea NRRL 2338] gi|133913937|emb|CAM04050.1| possible sodium/hydrogen antiporter [Saccharopolyspora erythraea NRRL 2338] Length=527 Score = 258 bits (659), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 192/500 (39%), Positives = 283/500 (57%), Gaps = 9/500 (1%) Query 41 PVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREIRWNLRVIVMFSI 100 P++L++ G+ +G +P V +D E+VL++FLP +LYW +++ +F ++R NLR + + S+ Sbjct 30 PIVLVVGGAAIGFLPGLPHVHLDPEIVLVVFLPPLLYWAALSANFHDLRENLRALTLSSV 89 Query 101 GLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPTDAAAVAGLAKRL--PRRALTVLRG 156 GLV+ATA AV+ A AL G+ AA LG ++SPTD A + +RL PRR ++ + G Sbjct 90 GLVLATAGAVAVLAHALVPGLSWPAAFALGTIVSPTDPLAAGLVMRRLGAPRRLVSAVEG 149 Query 157 ESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLGGIMAGLLVGGLVTLLRRRI 216 E L ND TALV + V VA G G+ FV GGI GL+VG LV L+RR Sbjct 150 EGLFNDATALVAYRVAVAAIVGE-GMSYGNAGLAFVAGAAGGIAIGLVVGWLVALIRRHT 208 Query 217 DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIRARSRLQAHAFWD 276 +SLL+ +AAF+ A +L SGV+A + + L + G T + AR+RLQ WD Sbjct 209 TDAQVSLTISLLSGYAAFIPANALGASGVLAAVTTGLYMGVRGVTTLPARTRLQGFLVWD 268 Query 277 IATFLINGSLWVFVGVQIPGAIDHIAGEDGG-LPRATVLALAVTGVVIATRIAWVQATTV 335 I FLIN L+V VG+Q+ A++ +A L R ALAV G V+ R+ W Sbjct 269 IINFLINAVLFVLVGLQLRSALEGLAEYTAADLAR---YALAVAGTVVVVRLVWFFTVPY 325 Query 336 LGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNSGAPFPDRNLIIFV 395 L +DR + R VG R R V +W+G RG+VSLAAALA+P+ G PF R+LIIF+ Sbjct 326 LIRILDRRPGQRERRVGARHRLVLAWSGMRGSVSLAAALALPLAVAPGFPFAARDLIIFL 385 Query 396 VSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLARTRSAQAALDALPTVADELGVA 455 V VI T++VQG SLP ++R R+ ++ A + AR + + AL + +A E Sbjct 386 VFAVIFATLVVQGLSLPGLIRLLRVTDEGAEERQELRARLEATETALAQIDELAAEEWTR 445 Query 456 PDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLVRRVRLGVLQHQRQAVTTLRNQNL 515 D V+ + + YE R + A + D +R+ +++ VLQ QR V LR++ Sbjct 446 DDSVERMRRAYEYRGRRLGARADQESEHDYEDRSLAYQQMVRVVLQAQRTTVVRLRDRGE 505 Query 516 IDDIVLRELQAAMDLEEVQL 535 I + V+ + DLEE +L Sbjct 506 ISNEVMTRIIRDFDLEEARL 525 >gi|326773839|ref|ZP_08233121.1| Na+/H+ antiporter [Actinomyces viscosus C505] gi|326635978|gb|EGE36882.1| Na+/H+ antiporter [Actinomyces viscosus C505] Length=534 Score = 256 bits (655), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 183/537 (35%), Positives = 288/537 (54%), Gaps = 19/537 (3%) Query 18 VIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILY 77 +IVAL+ A VV + +R+R+ PVLLI +G + L+P ++ + VVL +FLP +LY Sbjct 5 MIVALIGASVVAYAIANRFRLIAPVLLIAAGVGVALLPVGEEMSLPSTVVLTIFLPILLY 64 Query 78 WESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDAA 137 WES++ S +R +LR I++ + LV TA ++ G+ AA ++GA L PTDA Sbjct 65 WESLSVSLNRMRRSLRGIILSATVLVAITAALITLIGVLTGLSVGAALLIGACLGPTDAT 124 Query 138 AVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLG 197 AV+ L + TVL+ ESL+NDGTALV+FA+ + A ++G+ + + ++S+ G Sbjct 125 AVSSLGCGINPNGRTVLQAESLLNDGTALVIFAIALQAAHDSSGVTFGLVTHQLLLSFGG 184 Query 198 GIMAGLLVGGLVTLLRRRI----DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSAL 253 GI AG+LVG VT + R+ D P+ +L TPF F +A+ + SGV+AV+ + Sbjct 185 GIGAGVLVGAAVTKIGIRVRTITDDPMLATITALATPFLTFFVAEEIGGSGVLAVVTCGI 244 Query 254 VLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATV 313 V++ + SR+ FW I T ++N L+V VGV +PG + + D L R + Sbjct 245 VISRFAAPHMSLGSRVLGIPFWTILTHILNTILFVMVGVALPGIVAELPRAD--LVRGLI 302 Query 314 LALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAA 373 L + ++A R A +DR ++ R R R V++ AGFRGA+SLA A Sbjct 303 LIPIIYIAMVAGRFAGQHLIIYSIRALDRRPEQRLRRTNIRGRIVSTVAGFRGAISLAMA 362 Query 374 LAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLA 433 L++P T+ GA + +RNLII VV+ L+++L+QG +LP VVRWA A + A Sbjct 363 LSIP-TSFDGAAYAERNLIILVVAGATLLSLLIQGLALPYVVRWAN-ARPSAGTQTAESA 420 Query 434 RTRSAQAALD-------ALPTVADELGVAPD-LVKHLEKEYEERAVLVMADGADSATSDL 485 ++ +A D L +A+ GV D ++ + +Y R V A+ S Sbjct 421 ESQETEALADILADTISQLDAIAERAGVDDDAAIEAVRADYARRHDSVSNANAEEEASVY 480 Query 486 AERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 ++ +RL V++H R+ V +LR IDD + D+E + + P D E Sbjct 481 GDQES---ALRLAVIEHLRERVQSLRFAGRIDDSTASRVNRRFDVETLHINGPLDVE 534 >gi|325067898|ref|ZP_08126571.1| CPA1 family monovalent cation:proton (H+) antiporter-1 [Actinomyces oris K20] Length=534 Score = 253 bits (647), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 179/536 (34%), Positives = 287/536 (54%), Gaps = 17/536 (3%) Query 18 VIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILY 77 +IVAL+ A +V + +R+R+ PVLLI++G + L+P ++ + VVL +FLP +LY Sbjct 5 MIVALIGASIVAYAIANRFRLIAPVLLIVAGVGVALLPVGEEMYLPSTVVLTIFLPILLY 64 Query 78 WESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDAA 137 WES++ S +R +LR I++ + LV TA ++ +G+ AA ++GA L PTDA Sbjct 65 WESLSVSLNRMRRSLRGIILSATVLVAITAALITLIGVLMGLSVGAALLIGACLGPTDAT 124 Query 138 AVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLG 197 AV+ L + + + T+L+ ESL+NDGTALV+FA+ + A+ ++G+ + + ++S+ G Sbjct 125 AVSSLGRGINPNSRTILQAESLLNDGTALVIFAIALQAAQDSSGVTFGLITHQLLLSFGG 184 Query 198 GIMAGLLVGGLVTLLRRRI----DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSAL 253 GI AG+LVG VT + RI D P+ +L TPF F +A+ + SGV+AV+ + Sbjct 185 GIGAGVLVGAAVTKIGIRIRTITDDPMLATITALATPFLTFFIAEEIGGSGVLAVVTCGI 244 Query 254 VLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATV 313 V++ + SR+ FW I T ++N L+V VGV +PG + + D L R + Sbjct 245 VISRFAAPHMSLGSRVLGIPFWTILTHILNTILFVMVGVALPGIVAELPHAD--LVRGLI 302 Query 314 LALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAA 373 L + +++ R A +DR ++ R R R V++ AGFRGA+SLA A Sbjct 303 LIPIIYIAMVSGRFAGQHLIIFSIRALDRRPEQRLRRTNIRGRIVSTVAGFRGAISLAMA 362 Query 374 LAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM-PEDVAHANELQL 432 L++P++ + GA +RNLII VV+ L+++L+QG +LP VVRWA P E Sbjct 363 LSIPVSFD-GAASTERNLIILVVAGATLLSLLIQGLALPYVVRWANARPSAGTQTAECVE 421 Query 433 ARTRSAQA-----ALDALPTVADELGVAPD-LVKHLEKEYEERAVLVMADGADSATSDLA 486 ++ A A + L +A GV D ++ + Y R V+ +S Sbjct 422 SQETDALAEILADTISQLDAIAKRTGVDDDEAIEAVRLHYARRHQSVLNSATESEADVYC 481 Query 487 ERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 +RL V++H R+ V LR IDD + D+E + + P D E Sbjct 482 GPES---ALRLAVIEHLRERVHGLRFSGRIDDSTASRVNRRFDVETLHINGPLDVE 534 >gi|329944091|ref|ZP_08292350.1| Na+/H+ antiporter [Actinomyces sp. oral taxon 170 str. F0386] gi|328530821|gb|EGF57677.1| Na+/H+ antiporter [Actinomyces sp. oral taxon 170 str. F0386] Length=534 Score = 251 bits (641), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 186/536 (35%), Positives = 291/536 (55%), Gaps = 17/536 (3%) Query 18 VIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILY 77 +IVAL+ A +V V+ R+R+ PVLLI +G ++ IP G++ + VVL +FLP +LY Sbjct 5 MIVALIGASIVAYVIADRFRLIAPVLLIAAGVVVAFIPFEGEMTLPSTVVLTIFLPILLY 64 Query 78 WESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDAA 137 WES++ S +R +LR I++ + LV TA ++ G+ AA ++GA L PTDA Sbjct 65 WESLSVSLNRMRRSLRGIILSATVLVAITAALIALIGVLTGLSLGAALLIGACLGPTDAT 124 Query 138 AVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLG 197 AV+ L + + TVL+ ESL+NDGTALV+FA+ + A+ ++G+ + ++S+ G Sbjct 125 AVSSLGRGINPNGRTVLQAESLLNDGTALVVFAIALQTAQDSSGVTAGLVTRELLLSFGG 184 Query 198 GIMAGLLVGGLVTLLRRRI----DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSAL 253 GI G +VG +VT + R+ D P+ +L TPF F A+ + SGV+AV+ + Sbjct 185 GIGVGAVVGAVVTKIGIRVRTITDDPMLATITALATPFVTFFFAEEIGGSGVLAVVTCGI 244 Query 254 VLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATV 313 +++ + SR+ FW I T+++N L+V VGV +PG + D L R V Sbjct 245 IVSRFAAPHLPLGSRVLGTPFWTILTYILNTILFVMVGVALPGIAADLPRAD--LTRGLV 302 Query 314 LALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAA 373 L + ++A R A +DR ++ R FR R V++ AGFRGA+SLA A Sbjct 303 LIPIIYIAMVAGRFAGHHLIIYSIRALDRRPEQRLRRTNFRGRVVSTVAGFRGAISLAMA 362 Query 374 LAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWA-RMPEDVAHANELQL 432 L++P+T + GA F +R+LII +V+ V L+++LVQG +LP VVRWA P E Sbjct 363 LSIPVTFD-GAAFVERDLIILIVAGVTLLSLLVQGIALPYVVRWANERPSIGMRTAESIE 421 Query 433 ARTRSAQAA-----LDALPTVADELGVAPD-LVKHLEKEYEERAVLVMADGADSATSDLA 486 +R A A ++ + +A+ GV D ++ + +Y+ R V GA+ + Sbjct 422 SRETEALAGILGDTINEIEAIAESAGVDDDAVISAVRADYKRRYTSVSNAGAE---EEAR 478 Query 487 ERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 D +RL V+ H RQ V LR IDD + +D+E + + P D E Sbjct 479 VYGDPESALRLAVIDHLRQRVHDLRFSGRIDDSTASNVNRRLDVETLHINGPIDVE 534 >gi|312886601|ref|ZP_07746209.1| sodium/proton antiporter, CPA1 family (TC 2.A.36) [Mucilaginibacter paludis DSM 18603] gi|311301004|gb|EFQ78065.1| sodium/proton antiporter, CPA1 family (TC 2.A.36) [Mucilaginibacter paludis DSM 18603] Length=538 Score = 249 bits (637), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 158/513 (31%), Positives = 281/513 (55%), Gaps = 15/513 (2%) Query 21 ALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWES 80 L+ ++ +L + ++ P+LL+L G LG +P ++I E++ ++FLP +LY + Sbjct 10 CLLIIILFTVMLAQKIKIAYPILLVLIGLPLGFVPFLRGIEIKPELIFVIFLPPLLYESA 69 Query 81 MNTSFREI-RWNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPTDAA 137 NTS+++ +W RVI F+ +VI T+ V++ + AL G +LG ++SP DA Sbjct 70 WNTSWKDFWKWR-RVISSFAFPVVIITSCVVAFVSSALIPGFSLATGFLLGGIVSPPDAV 128 Query 138 AVAGLAK--RLPRRALTVLRGESLINDGTALVLFAVTVA-VAEGAAGIGPAALVGRFVVS 194 + + + K ++P+R +T++ GESL+ND ++LV+F +A V G+ AA+ FV+ Sbjct 129 SASAILKNIKVPKRFITIVEGESLMNDASSLVVFRFALAAVLTGSFVFSQAAV--SFVLV 186 Query 195 YLGGIMAGLLVGGLVTLLRRRIDAPLE-EGALSLLTPFAAFLLAQSLKCSGVVAVLVSAL 253 + GI GL++ L + R + + L+ +TP+A ++ A+ SGV+AV+ L Sbjct 187 IVMGIAIGLVIALLFYAMHRWLPTSANMDVVLTFITPYAMYITAEEFHFSGVLAVVSGGL 246 Query 254 VLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATV 313 L+ + + RSRLQ W+ F++NG +++ +G++ P + + G DG L A + Sbjct 247 FLSAQRHSFLSNRSRLQGINVWEAVAFVLNGFVFILIGLEFPMIVKDL-GRDG-LQSAII 304 Query 314 LALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAA 373 +L + GV+IATR A T++ + +++ G+R + W G RG VSLAAA Sbjct 305 YSLIINGVLIATRFASTFGATLITMLMSKIITVADPTPGWRAPILFGWTGMRGVVSLAAA 364 Query 374 LAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPE---DVAHANEL 430 L++P+ +SG PFP R+LI+F+ VILV++++QG +LP +V+W MP+ V+ + Sbjct 365 LSIPVALSSGQPFPYRSLILFITFTVILVSLILQGLTLPALVKWVNMPDPDYTVSFEQQK 424 Query 431 QLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERND 490 Q+ R + + AL L + ++V L+ + E L+ D E D Sbjct 425 QMVRKKLSNLALTILKEQYPQQAQQNNMVVSLKLKLETDMELLKDWEQDGNQQRADEYYD 484 Query 491 LVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRE 523 R++ + QR+ + TL + IDD ++R+ Sbjct 485 EYRKIMTHLTGEQRKLLLTLNKKENIDDDIVRQ 517 >gi|256820476|ref|YP_003141755.1| Na+/H+ antiporter [Capnocytophaga ochracea DSM 7271] gi|256582059|gb|ACU93194.1| Na+/H+ antiporter [Capnocytophaga ochracea DSM 7271] Length=524 Score = 249 bits (636), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 171/531 (33%), Positives = 288/531 (55%), Gaps = 43/531 (8%) Query 22 LVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESM 81 L+ A+++ +L +R +V P+LL+L G + IP + ++ ++VL++FLP +LY + Sbjct 11 LMVAIMLLIMLANRLKVAYPILLVLGGLAISFIPNVPTITLNPDLVLIIFLPPLLYADVF 70 Query 82 NTSFREI-RWNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPTDAAA 138 + S +E+ +W R+I F+ +V TA AV+W A + G +LG V+ TDA + Sbjct 71 SLSLKEMWKWR-RIIFSFAFIVVFITAAAVAWVANMVFPGFSLALGFLLGGVIGSTDAVS 129 Query 139 VAGLAK--RLPRRALTVLRGESLINDGTALVLFAVT-VAVAEGAAGIGPAALVGRFVVSY 195 + + K ++P+R T++ ESL+ND ++L++F + V G AL +VV Sbjct 130 ASSIMKFVKVPKRISTIIESESLLNDASSLIVFRFAALVVTTGQLVWTDMALNFLWVV-- 187 Query 196 LGGIMAGLLVGGLVTLLRRRI--DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSAL 253 +GG + GL V ++ L R + DA ++ L+L+ P+ +++A + SGV+AV+ + Sbjct 188 IGGTLIGLAVAWVMRKLHRFLPTDANMDI-ILTLIAPYIMYIVANEVGASGVLAVVAGGM 246 Query 254 VLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATV 313 +++ +++ A +R + A WDI F++NG ++ +G+ +P + I E L AT Sbjct 247 YMSFHLTSILAASTRNKGVAVWDILGFVLNGLAFMLIGLALPEVLIGIEAEGMSLATATN 306 Query 314 LALAVTGVVIATRI----AWVQATTVLGHTV---DRVLKKPTRHVGFRQRCVTSWAGFRG 366 L +TGVV+ R+ + T V+ H + DR R+ GFR V WAG RG Sbjct 307 YGLLITGVVVGVRLLSSYGAILITQVMKHFITVADR------RNPGFRVPLVLGWAGMRG 360 Query 367 AVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAH 426 +SLA AL++P+T +G PFP RNLI+++ +VILVT+LVQG SLP ++RWA+ P+ H Sbjct 361 VLSLAVALSIPLTLENGEPFPHRNLILYITFIVILVTLLVQGLSLPALIRWAKFPDYEDH 420 Query 427 ANELQ---LARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATS 483 E + L R AQAALD + E G+ + +K+ + + Sbjct 421 IPEAEAESLIRKSLAQAALDYMQEHYKE-GITDSFLLQNQKDIWQYQL------------ 467 Query 484 DLAERNDL--VRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEE 532 DL + N VR+ + +L HQR+ + L ID+ +R ++LEE Sbjct 468 DLPKSNTTPEVRKKYIAILHHQREILHQLNKNPRIDEEQIRNFHRQLNLEE 518 >gi|284046425|ref|YP_003396765.1| Na+/H+ antiporter [Conexibacter woesei DSM 14684] gi|283950646|gb|ADB53390.1| Na+/H+ antiporter [Conexibacter woesei DSM 14684] Length=553 Score = 249 bits (635), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 186/524 (36%), Positives = 295/524 (57%), Gaps = 8/524 (1%) Query 17 VVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAIL 76 VV++ ++A V V +L + RV P+ L++ G L +P V++D ++VLL+ LP +L Sbjct 27 VVLLGVLAGVTVLLLLAYHSRVPYPIWLVVGGGALAFVPGLPQVELDPDLVLLVILPPLL 86 Query 77 YWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPT 134 Y + +S R++R NLR I M +IGLV+AT + V A + + AA LGAVLSPT Sbjct 87 YAAAFFSSLRDLRANLRPIGMLAIGLVVATTLVVGVVAHMVVDDLSWAAAFTLGAVLSPT 146 Query 135 DAAAVAGLAKRL--PRRALTVLRGESLINDGTALVLFAVTVA-VAEGAAGIGPAALVGRF 191 D A +A R PRR +T++ GESL+ND TAL+++ VA V G+ + A F Sbjct 147 DPVAATAIASRAGAPRRFVTIVEGESLVNDSTALIIYKAAVAAVLTGSFSLLDAGF--DF 204 Query 192 VVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVS 251 V+ GI G+ +G ++ +RR +D P E +SLLTP+ A+L A++L S V+A + S Sbjct 205 VMGAAAGIAIGIAIGAVIARIRRVVDDPPTEITISLLTPYFAYLPAEALGVSAVLAAVTS 264 Query 252 ALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRA 311 + L + P +I +R+QA + W+I F++N +L+V VG+Q+PG ++ I+ +D + Sbjct 265 GIWLGWRSPELITPATRIQAFSVWEILVFVLNAALFVLVGLQLPGIVEQIS-DDYAAGQL 323 Query 312 TVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLA 371 + V VI R AWV T L + R +++ + SW G RGAVSLA Sbjct 324 ALWGALVAVTVILVRFAWVFPLTYLPGLLSRRVRERNPFPPVTSVLLISWTGMRGAVSLA 383 Query 372 AALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQ 431 AALA+P+T + G+PFP R+LI+F+V V ILVT+L QG +L ++R + +D Sbjct 384 AALAIPLTLDDGSPFPGRDLIVFLVYVTILVTILAQGLTLAPLIRLLGVEDDGKVERLEA 443 Query 432 LARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDL 491 AR ++A+ A+ + +A E V + + YE R + D + R+ Sbjct 444 KARVKAAKRAIARIDELAAEDWVGDLTAERMRGLYEFRIQRFRSRFDDEDDGAVEARSLA 503 Query 492 VRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQL 535 +R+R L +R + LRN+ +I+D VL ++ +DLE+ +L Sbjct 504 YQRLRREALGAERAEIIRLRNEGVINDAVLHTIERDLDLEDTRL 547 >gi|255036633|ref|YP_003087254.1| Na+/H+ antiporter [Dyadobacter fermentans DSM 18053] gi|254949389|gb|ACT94089.1| Na+/H+ antiporter [Dyadobacter fermentans DSM 18053] Length=531 Score = 248 bits (633), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 159/532 (30%), Positives = 294/532 (56%), Gaps = 20/532 (3%) Query 15 GLVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPA 74 L++I++L+ V + T+L + + P+ L+++G L+ +P +Q++ + V L+FLP Sbjct 5 NLLLIISLLFVVSMLTMLSEKIGISYPIFLVIAGLLISFVPGMPHLQLEPDWVFLIFLPP 64 Query 75 ILYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLS 132 +LY + NTS+++ + R I + SIGLV+ TA AV++ AL G VLG ++S Sbjct 65 LLYEAAWNTSWKDFWASRRAIGLLSIGLVVFTATAVAYITHALIPGFTLAMGFVLGGIIS 124 Query 133 PTDAAAVAGLAK--RLPRRALTVLRGESLINDGTALVLFAVTVAVAE-GAAGIGPAALVG 189 P DA A + ++P+R +T+L GESL+ND ++L++F V +A E G + A Sbjct 125 PPDAVAATSVLHGLKVPKRVVTILEGESLVNDASSLIVFRVALATIETGNFVLWKAG--A 182 Query 190 RFVVSYLGGIMAGLLVGGLVTLLRRRI-DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAV 248 F++ + G++ GL + ++ ++ R P + AL+ ++P+ ++ A+ SGV+AV Sbjct 183 DFLMVAVMGVVIGLAIAHVLYVVHRFFPTTPSIDTALTFISPYLMYITAEHFHYSGVLAV 242 Query 249 LVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGL 308 + L L++ + +SR+Q + W FL+NG +++ +G+Q+P I+ + + Sbjct 243 VSGGLFLSFRAHELFTYQSRMQTNYVWQTVVFLLNGIVFILIGLQLPEVINGL--NEYTT 300 Query 309 PRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAV 368 A+ ++ V I RI WV T L + + +++ ++ + +W+G RG V Sbjct 301 SEVVSYAVIISIVTILIRIIWVFPGTYLPRILSKSVRQREPKPSWQTVFIVAWSGMRGVV 360 Query 369 SLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMP-EDVAHA 427 SLA+ALA+P+ N G PFP RNL +F+ VVIL T++ QG SLP +++W ++ +D + Sbjct 361 SLASALAIPLLVN-GQPFPHRNLFLFITFVVILFTLVFQGLSLPYLIKWLKIEDDDDSLE 419 Query 428 NELQLARTRSAQAALDALPTVADELGVAPDL--VKHLEKEYEERAVLVMADGADSATSDL 485 E + +R A +LD + + D G D + L++ YE+ ++ MAD + D Sbjct 420 KENAMMNSRLATVSLDYMKSNYD--GEIQDFEPFRLLKERYEK--IVEMADYKLLHSEDN 475 Query 486 AERNDL--VRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQL 535 + + RR+ L ++ +R+ + LR + + ++R + +DLEE +L Sbjct 476 KSISHVRKYRRMLLEIIDVKREEILKLRQERACSNELIRTKEHELDLEEARL 527 >gi|332879133|ref|ZP_08446834.1| Na+/H+ antiporter [Capnocytophaga sp. oral taxon 329 str. F0087] gi|332682933|gb|EGJ55829.1| Na+/H+ antiporter [Capnocytophaga sp. oral taxon 329 str. F0087] Length=524 Score = 243 bits (619), Expect = 7e-62, Method: Compositional matrix adjust. Identities = 163/538 (31%), Positives = 285/538 (53%), Gaps = 57/538 (10%) Query 22 LVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESM 81 L+ A+++ + +R +V P+LL+L G + IP + ++ ++VL++FLP +LY + Sbjct 11 LMVAIMLLIMFANRLKVAYPILLVLGGLAISFIPNVPTITLNPDLVLIIFLPPLLYADVF 70 Query 82 NTSFREI-RWNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPTDAAA 138 + S +E+ +W R+I F+ +V TA AV+W A + G +LG V+ TDA + Sbjct 71 SLSLKEMWKWR-RIIFSFAFIVVFITAAAVAWVANMVFPGFSLALGFLLGGVIGSTDAVS 129 Query 139 VAGLAK--RLPRRALTVLRGESLINDGTALVLFAVT-VAVAEGAAGIGPAALVGRFVVSY 195 + + K ++P+R T++ ESL+ND ++L++F + V G AL ++ Sbjct 130 ASTIMKFVKVPKRISTIIESESLLNDASSLIVFRFAALVVTTGQLVWTDIAL------NF 183 Query 196 LGGIMAGLLVGGLVTLLRRRIDAPLEEGA-----LSLLTPFAAFLLAQSLKCSGVVAVLV 250 L ++ G L+G V + R+++ A L+ + P+ +++A + SGV+AV+ Sbjct 184 LWVVIGGTLIGLAVAWVMRKLNKFFPTDANMDIILTFIAPYIMYIVANEMGVSGVLAVVA 243 Query 251 SALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPR 310 + +++ +++ A + +A A WDI F++NG ++ +G+ +P ++ I E L Sbjct 244 GGMYMSFHITSILAASTYNKAVAVWDILGFVLNGLAFMLIGLALPDVLESIEAEGMSLAT 303 Query 311 ATVLALAVTGVVIATRI----AWVQATTVLGHTV---DRVLKKPTRHVGFRQRCVTSWAG 363 AT L +TGVV+ R+ + T V+ H + DR R++GFR V WAG Sbjct 304 ATNYGLLITGVVVGVRLLSSYGALLITQVMKHFITVADR------RNLGFRLPLVLGWAG 357 Query 364 FRGAVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPED 423 RG +SLA AL++P+T +G PFP R+LI+++ +VIL T+L QG SLP ++RWA+ P+ Sbjct 358 MRGVLSLAVALSIPLTLENGEPFPHRSLILYITFIVILATLLAQGLSLPALIRWAKFPDY 417 Query 424 VAHANELQ---LARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEE--RAVLVMADGA 478 H E + L R AQAALD +++K Y+E L++ + Sbjct 418 EDHIPEAEAESLIRKSLAQAALD-----------------YMQKHYKEGINDSLLLQNQK 460 Query 479 D--SATSDLAERNDL--VRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEE 532 D DL++ N R+ + +L HQR+ + L ID+ +R ++LEE Sbjct 461 DIWQYQLDLSKSNTTPEERKKYIAILHHQREILHQLNKNPRIDEEQIRNFHRQLNLEE 518 >gi|213962879|ref|ZP_03391139.1| Na+/H+ antiporter [Capnocytophaga sputigena Capno] gi|213954536|gb|EEB65858.1| Na+/H+ antiporter [Capnocytophaga sputigena Capno] Length=524 Score = 241 bits (616), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 166/529 (32%), Positives = 286/529 (55%), Gaps = 38/529 (7%) Query 22 LVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESM 81 L+ A+++ + +R +V P+LL+L G + IP + ++ ++VL++FLP +LY + Sbjct 11 LMVAIMLLIMFANRLKVAYPILLVLGGLAISFIPNVPTITLNPDLVLIIFLPPLLYADVF 70 Query 82 NTSFREI-RWNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPTDAAA 138 + S +E+ +W R+I F+ +V TA AV+W A + G +LG V+ TDA + Sbjct 71 SLSLKEMWKWR-RIIFSFAFIVVFITAAAVAWVANMVFPGFSLALGFLLGGVIGSTDAVS 129 Query 139 VAGLAK--RLPRRALTVLRGESLINDGTALVLFAVT-VAVAEGAAGIGPAALVGRFVVSY 195 + + K ++P+R T++ ESL+ND ++L++F + V G AL +VV Sbjct 130 ASTIMKFVKVPKRISTIIESESLLNDASSLIVFRFAALVVTTGQLVWTDMALNFLWVV-- 187 Query 196 LGGIMAGLLVGGLVTLLRRRI--DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSAL 253 +GG + GL V ++ L + + DA ++ L+ + P+ +++A + SGV+AV+ + Sbjct 188 IGGTLIGLGVAWVMRKLHKYLPTDANMDV-ILTFIVPYIMYIVANEVGASGVLAVVAGGM 246 Query 254 VLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATV 313 +++ +++ A + + A WDI F++NG ++ +G+ +P + I E L AT Sbjct 247 YMSFHLTSILAASTSNKGWAVWDILGFVLNGLAFMLIGLALPEVLIGIEAEGMSLATATN 306 Query 314 LALAVTGVVIATRI----AWVQATTVLGHTV---DRVLKKPTRHVGFRQRCVTSWAGFRG 366 L +TGVV+ R+ + T V+ H + DR R++GFR V WAG RG Sbjct 307 YGLLITGVVVGVRLLSSYGALLITQVMKHFITVADR------RNLGFRLPLVLGWAGMRG 360 Query 367 AVSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAH 426 +SLA AL++P+T +G PFP R+LI+++ +VIL T+LVQG SLP ++RWA+ P+ H Sbjct 361 VLSLAVALSIPLTLENGEPFPHRSLILYITFIVILATLLVQGLSLPALIRWAKFPDYEDH 420 Query 427 ANELQ---LARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATS 483 E + L R AQAALD + E G+ L+ +K+ + + D + S T+ Sbjct 421 IPEAEAESLIRKSLAQAALDYMQKHYKE-GINDSLLLQNQKDIWQYQL----DLSKSNTT 475 Query 484 DLAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEE 532 ER + +L HQR+ + L ID+ +R ++LEE Sbjct 476 TPEERKKYI-----AILHHQREILRQLNKNPRIDEEQIRNFHRQLNLEE 519 >gi|223694794|gb|ACN18076.1| Na+/H+ antiporter [uncultured bacterium BLR5] Length=543 Score = 239 bits (610), Expect = 9e-61, Method: Compositional matrix adjust. Identities = 159/527 (31%), Positives = 286/527 (55%), Gaps = 29/527 (5%) Query 26 VVVGTVL-GHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTS 84 +++G V+ ++ R+ P++L+L G L +F ++ ID E+V +FLP +LY + S Sbjct 14 IILGLVMVANKLRLAYPIVLVLGGLALSFSTKFSNITIDPELVFFIFLPPLLYEAAWQIS 73 Query 85 FREI-RWNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPTDAAAVAG 141 ++E +W RVI +F+ +V+ TA+ ++ + AL G +LGA++SP DA + Sbjct 74 WKEFWKWR-RVITVFAFPIVVITALVIALVSSALIPGFTLALGFLLGAIISPPDAISATT 132 Query 142 LAKRL--PRRALTVLRGESLINDGTALVLFAVTVA-VAEGAAGIGPAALVGRFVVSYLGG 198 + +R+ R ++++ GESL+ND ++L++F +A V G AA+ F + L G Sbjct 133 IMRRVNVSRSLVSIVEGESLLNDASSLIVFRFAIAAVVTGQFHFREAAV--SFFLVVLMG 190 Query 199 IMAGLLVGGLVTLLRRRI-DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTY 257 I+ GLLVG + + R + P E L+++TP+ + LA+S SGV+AV+ L L+ Sbjct 191 ILIGLLVGTIFYAIHRWLPTTPSIEIVLTVVTPYCMYYLAESFHFSGVLAVVSGGLFLSN 250 Query 258 VGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLALA 317 ++ RSR++ W+ F++NG +++ +G+Q+P + D L +A L Sbjct 251 RRQRMLNFRSRIEGVNVWNSLVFVLNGFIFMLLGLQLPAVTRQLG--DTSLSKAIGYGLL 308 Query 318 VTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVP 377 ++ V+I TR+ + + R + H G++ + W+G RG VSLA AL++P Sbjct 309 ISIVLIVTRMFCTLIASPFSTLMSRFITVADPHPGWKNPIILGWSGMRGVVSLAMALSIP 368 Query 378 MTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVV-------RWARMPEDVAHANEL 430 + G PFP RNLI+F+ +VIL+T++ QG +LP V+ ++ +PE H EL Sbjct 369 LVAGEGTPFPYRNLILFITFIVILLTLVFQGLTLPWVIQKVKPGDKYFGIPE---HEQEL 425 Query 431 QLARTRSAQAALDALPTVADELGVAPDLVKHLEK--EYEERAVLVMADGADSATSDLAER 488 + R +A+A+L L E V + V+ L + + + R+ + D + E Sbjct 426 LIERM-TAKASLQFLEQEYGEQRVDNEYVEILFRRLQIDLRS---LDQNFDESNGPREES 481 Query 489 NDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQL 535 + R + L +L+HQRQ + + N +D+ ++R+ + +DLEE ++ Sbjct 482 SKKYRSIYLQLLEHQRQVLNEMNNSANVDEELIRKYLSLIDLEEYKI 528 >gi|284047085|ref|YP_003397425.1| Na+/H+ antiporter [Conexibacter woesei DSM 14684] gi|283951306|gb|ADB54050.1| Na+/H+ antiporter [Conexibacter woesei DSM 14684] Length=531 Score = 237 bits (604), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 192/520 (37%), Positives = 280/520 (54%), Gaps = 28/520 (5%) Query 17 VVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAIL 76 + ++ L+ AV T L V P+LL++ GSLLG +P V++D ++VLL+FLP +L Sbjct 6 LTLLGLLIAVAGLTALARALNVPYPILLVIGGSLLGFVPGLPHVELDPDLVLLVFLPPLL 65 Query 77 YWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPT 134 + + S +E+R LR I++ SIGLV+ TAV V+ A AL + AA LGA+ +PT Sbjct 66 FHAAYFASVQELRRQLRPILLNSIGLVVLTAVTVALVAHALIDDLSWAAAFTLGAICAPT 125 Query 135 DAAAVAGLAKRL--PRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVG--- 189 D A + +RL P R +V+ GESLINDG+ALV++ VA A G G L+ Sbjct 126 DPLAATTITRRLGVPPRLTSVIEGESLINDGSALVIYRTAVAAAVG----GSFDLLDAGT 181 Query 190 RFVVSYLGGIMAGLLVG-GLVTLLRR-RIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVA 247 FVV GGI GL++G LV L RR R+D PL LSL+ + A++ A+ L SGV+A Sbjct 182 DFVVDVAGGIAIGLVMGYALVPLFRRARVD-PLLVVTLSLVNGYIAYISAEELHVSGVLA 240 Query 248 VLVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGG 307 + LVL + P + AR R+ + FWD+ FL+N L++ VG Q+ +DH G Sbjct 241 SVTVGLVLGWYSPYISDARGRVSGYGFWDVLVFLLNAVLFILVGFQLAQILDHQERSAGT 300 Query 308 LPRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGA 367 L +L V+ VI TR+AW+ + +DR + TR VG+R R V +W+G RGA Sbjct 301 L---LLLGTTVSLTVIVTRLAWLNTAPYVIRALDRRAVQRTRRVGWRPRIVVAWSGMRGA 357 Query 368 VSLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHA 427 VSLA FP+R+L++F+ VI T+++QG +LP V+R + +D + Sbjct 358 VSLA------AALALPLDFPERDLVLFLALCVIFATLVLQGLTLPAVIRKLDVRDDGSAE 411 Query 428 NELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEERAVLVMADGADSATSD--- 484 E LAR + AA+ L + +E V +L + Y+ R + ++A D Sbjct 412 REDLLARRAATDAAIARLHALHEEEWTRDSTVDYLLRNYDVRQRRLAQRAGEAAEEDGDG 471 Query 485 --LAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLR 522 L E V VL+ QR AV TLR I D V+ Sbjct 472 VPLEEHTRARAAVIREVLRAQRDAVYTLRKDGAIGDDVMH 511 >gi|320532804|ref|ZP_08033583.1| Na+/H+ antiporter [Actinomyces sp. oral taxon 171 str. F0337] gi|320134995|gb|EFW27164.1| Na+/H+ antiporter [Actinomyces sp. oral taxon 171 str. F0337] Length=534 Score = 236 bits (602), Expect = 8e-60, Method: Compositional matrix adjust. Identities = 182/536 (34%), Positives = 286/536 (54%), Gaps = 17/536 (3%) Query 18 VIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILY 77 +IVAL+ A VV + +R+R+ PVLLI +G + L+P ++ + VVL +FLP +LY Sbjct 5 MIVALIGASVVAYTIANRFRLIAPVLLIAAGVGVALLPVGEEMYLPSTVVLTIFLPILLY 64 Query 78 WESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTDAA 137 WES++ S +R +LR I++ + LV TA ++ G+ AA ++GA L PTDA Sbjct 65 WESLSVSLNRMRRSLRGIILSATVLVAITAALIALIGVLTGLSVGAALLIGACLGPTDAT 124 Query 138 AVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLG 197 AV+ L + + TVL+ ESL+NDGTALV+FA+ + A+ ++G+ + ++S+ G Sbjct 125 AVSSLERGINPNGRTVLQAESLLNDGTALVIFAIALQAAQDSSGVTAGLVTRELLLSFGG 184 Query 198 GIMAGLLVGGLVTLLRRRI----DAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSAL 253 G+ AG+LVG VT + R+ D P+ +L TPF F LA+ + SGV+AV+ + Sbjct 185 GVGAGVLVGAAVTKIGIRVRTITDDPMLATITALATPFVTFFLAEEVGGSGVLAVVTCGI 244 Query 254 VLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATV 313 V++ + SR+ FW I T ++N L+V VGV +PG + + D L R + Sbjct 245 VISRFATPHMSLGSRVLGVPFWTILTHILNTILFVMVGVALPGIVAELPHAD--LVRGLI 302 Query 314 LALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAA 373 L + ++A R A +DR ++ R R R V++ AGFRGA+SLA A Sbjct 303 LIPIIYIAMVAGRFAGQHLIIYSIRALDRRPEQRLRRTNIRGRIVSTVAGFRGAISLAMA 362 Query 374 LAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM-PEDVAHANELQL 432 L++P++ + GA + +RNLII VV+ L+++L+QG +LP VVRWA P E Sbjct 363 LSIPVSFD-GAAYTERNLIILVVAGATLLSLLIQGIALPYVVRWANARPSAGTQTAECVE 421 Query 433 ARTRSAQA-----ALDALPTVADELGVAPD-LVKHLEKEYEERAVLVMADGADSATSDLA 486 ++ A + L +A+ GV D ++ + +Y+ R V SA + Sbjct 422 SQETEVLADVLADTISQLDAIAERAGVDDDAAIEAVRADYQRRHSSV---SNVSAEEEAR 478 Query 487 ERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 D +RL V++H R+ V LR IDD + D E + + P D E Sbjct 479 VYGDQESALRLAVIEHLRERVHDLRFAGRIDDSTASNVNRRFDAETLHINGPIDVE 534 >gi|302038904|ref|YP_003799226.1| putative Na+/H+ antiporter [Candidatus Nitrospira defluvii] gi|300606968|emb|CBK43301.1| putative Na+/H+ antiporter [Candidatus Nitrospira defluvii] Length=538 Score = 236 bits (601), Expect = 9e-60, Method: Compositional matrix adjust. Identities = 183/528 (35%), Positives = 282/528 (54%), Gaps = 16/528 (3%) Query 16 LVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAI 75 L VI+ L+A V+ T + + R+ P+ L+L G LGL+P V ++ ++V L+FLP I Sbjct 7 LEVIIMLLAVVLALTTIAQKIRIPYPIFLVLGGLALGLVPGLPAVTLNPDLVFLVFLPPI 66 Query 76 LYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSP 133 L+ + TS RE R NLR I + ++GLV+AT+ V++ A AL G+ A LGA++SP Sbjct 67 LWAAAYFTSLREFRRNLRPISLLAVGLVLATSAGVAFVAHALLPGIGWAEAIALGAIVSP 126 Query 134 TDAAAVAGLAKRL--PRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAAL---V 188 DA + + KRL PRR +T+L GESL+ND TALVL+ V GAA G AL + Sbjct 127 PDAVSATAIGKRLRIPRRIVTILEGESLVNDATALVLYRAAV----GAAMSGSFALGHTL 182 Query 189 GRFVVSYLGGIMAGLLVGGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAV 248 FV + L G++ G+ V L D + ++LL P+ A++ +S+ S V+A Sbjct 183 FEFVFAALAGVVIGIGVAWLTRWALCATDDGFTQIGVTLLAPYIAWVCGESVHASAVLAC 242 Query 249 LVSALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGL 308 + L L + +RLQA A WD+ F++NG +++ +G+Q+ D +A G Sbjct 243 VAGGLYLRQSFSGAVSPATRLQARAVWDLLIFILNGVIFILIGLQLGALRDSVA--PGQF 300 Query 309 PRATVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAV 368 + V+ I R WV ++ + L+ + + SW G RG V Sbjct 301 GPVLIAGAWVSATAILVRFLWVPLAALIPRWLSPTLRARDPMPPWSALFLISWTGMRGIV 360 Query 369 SLAAALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHAN 428 +LAAALA+P+TT+SG PFP R+ II + VIL T+++QG SLP ++R + ED Sbjct 361 TLAAALALPVTTSSGVPFPFRSEIILISFTVILATLVLQGLSLPPIIRLIPLQEDDGLEQ 420 Query 429 ELQLARTRSAQAALDALPTVADELGVAPDLVKHLEKEYEER-AVLVMADGADSATSDLAE 487 E LAR +A AAL+ L V E V+ + V+ + Y +R L A A+ S Sbjct 421 EETLAREHAATAALNRLDQVITENWVSLEQVERVRLRYIQRLERLTRASLAEEQMST--S 478 Query 488 RNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQL 535 + V+R++ + +R A+ LR+ I D VL L+ +D+ + L Sbjct 479 TAETVQRLQHEAMTAERMALIGLRDNGTISDEVLHRLEQELDVAALHL 526 >gi|326800189|ref|YP_004318008.1| Na+/H+ antiporter [Sphingobacterium sp. 21] gi|326550953|gb|ADZ79338.1| Na+/H+ antiporter [Sphingobacterium sp. 21] Length=534 Score = 234 bits (598), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 154/523 (30%), Positives = 279/523 (54%), Gaps = 26/523 (4%) Query 31 VLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREI-R 89 +L R ++ P+LL++ G + IP + I+ ++V L+FLP +L+ + TS+ E + Sbjct 21 LLSQRLKISYPILLVIGGLGICFIPGVRAISINPDLVFLIFLPPLLFEAAWYTSWNEFWK 80 Query 90 WNLRVIVMFSIGLVIATAVAVSWTARAL--GMESHAAAVLGAVLSPTDAAAVAGLAK--R 145 W R I + GLV+ T++AV++ + G +LG ++SP DA A + K Sbjct 81 WR-RSIGLLGFGLVLFTSLAVAYISVMTIPGFTLAMGFLLGGIISPPDAVAATSVLKGVT 139 Query 146 LPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSYLGGIMAGLLV 205 +P+R L +L GESL+ND +L +F +A I AL+ F + G++ GL + Sbjct 140 MPKRGLAILEGESLVNDAASLTVFRFALAAVLTGHFILQEALL-EFATLSIMGVVVGLAI 198 Query 206 GGLVTLLRRRIDAPLE-EGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIR 264 ++ + R + ++L+ P+ +L+A+S + SGV+AV+ L L++ + Sbjct 199 AHILYFVLRYLAKSSNITTPITLIAPYLMYLVAESFEWSGVLAVVSGGLFLSFRSKDFLN 258 Query 265 ARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVLALAVTGVVIA 324 +R+QA W FL+NG +++ +G+++P ++ + G A AL ++ VVI Sbjct 259 YHTRIQATEVWATVGFLLNGFVFILIGLELPVIVNGLEGYSK--KEAIQYALIISAVVIL 316 Query 325 TRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNSGA 384 R+ V + V + ++ GF+ WAG RG VSLA+ALA+P+T +G Sbjct 317 LRLTLVYLAAFIPRLVSKRIRDKETSPGFKLPFAIGWAGMRGVVSLASALAIPLTLENGE 376 Query 385 PFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMP---EDVAHANELQLARTRSAQAA 441 FP RNLI+F+ VVIL+T++ QG +LP ++ ++ E V ++L+ R + A+++ Sbjct 377 AFPHRNLILFITFVVILITLVFQGLTLPFFLKLLKIEEIDEYVPTEDQLEAIRLQLAKSS 436 Query 442 LDALPTVAD-ELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLV------RR 494 + L D E+ P + + KE +R++ D +S+ + ++ L+ RR Sbjct 437 IKYLDRKYDREMEEHPTIARI--KEQLQRSI----DATESSLQEQEKKEKLISVRMLYRR 490 Query 495 VRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLD 537 + L ++ H+R+ + LR + DD V+R+L+ +DLEE +L+ Sbjct 491 IMLELITHRREGLNKLRKEKKYDDHVIRQLEHNLDLEESRLIK 533 >gi|320094094|ref|ZP_08025909.1| putative Na+/H+ antiporter [Actinomyces sp. oral taxon 178 str. F0338] gi|319978985|gb|EFW10513.1| putative Na+/H+ antiporter [Actinomyces sp. oral taxon 178 str. F0338] Length=534 Score = 234 bits (597), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 168/538 (32%), Positives = 275/538 (52%), Gaps = 17/538 (3%) Query 16 LVVIVALVAAVVVGTVLGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAI 75 L +++ + A +V T L +R+R+ PV+LI++G + P + EVVL +FLP + Sbjct 3 LELLIIVCVAAIVATALTNRFRLIGPVMLIVAGLVASFAPGAEGAGLPSEVVLTVFLPVL 62 Query 76 LYWESMNTSFREIRWNLRVIVMFSIGLVIATAVAVSWTARALGMESHAAAVLGAVLSPTD 135 LYWE+++ S +R LR I++ + LV+ T+ + A+G+ + AA ++GA L PTD Sbjct 63 LYWEALSVSLNGMRRALRGIILSATVLVVITSAIIMAAGLAMGLSAGAALLVGACLGPTD 122 Query 136 AAAVAGLAKRLPRRALTVLRGESLINDGTALVLFAVTVAVAEGAAGIGPAALVGRFVVSY 195 A AVA L K + R TVL+ ESL+NDGTAL +FA+ + VA G G+ A++ F +S Sbjct 123 ATAVAALGKGINRFGRTVLQAESLLNDGTALAVFAIALRVASGGTGVSAASVASEFAISI 182 Query 196 LGGIMAGLLVGGLVTLLRRRIDAPLEEGALS----LLTPFAAFLLAQSLKCSGVVAVLVS 251 G+ G++ G LL + +A + LS L PF + LA+ L+ SGV+AV+ Sbjct 183 GAGLGVGVVCGTAAVLLWAKWNASRTDAMLSNLIALTVPFTTYFLAEELQGSGVLAVVAC 242 Query 252 ALVLTYVGPTVIRARSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRA 311 +V + + RL FW + T+L+N L++ VG+ +P + + ++ L R Sbjct 243 GIVYSRYNGNANDSAIRLVGIPFWSVLTYLMNTVLFIMVGLSLPDIVRRLPHQE--LVRG 300 Query 312 TVLALAVTGVVIATRIAWVQATTVLGHTVDRVLKKPTRHVGFRQRCVTSWAGFRGAVSLA 371 VL + ++A R A +DR ++ R R R V++ AGFRGA+SLA Sbjct 301 LVLIPIIYSAMVAARFVGHHAIIFSIRALDRRPQQRERRTNIRGRLVSTVAGFRGAISLA 360 Query 372 AALAVPMTTNSGAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARM-PEDVAHANEL 430 AL++P + G + +R+L++ + + V L++++VQG +LP VVRWA P V Sbjct 361 MALSIP-GSFGGTAYEERDLVVLITAGVTLLSLVVQGIALPHVVRWANARPTAVQRREAE 419 Query 431 QLARTRSAQAAL-----DALPTVADELGVAP-DLVKHLEKEYEERAVLVMADGADSATSD 484 +L A + + LP++A +GV +LV + + Y R ++ ++ S Sbjct 420 ELDEETRVLAGIMRDIVEELPSMAQRIGVEDGELVNAIRESYGRREERMLQAASEEEFSF 479 Query 485 LAERNDLVRRVRLGVLQHQRQAVTTLRNQNLIDDIVLRELQAAMDLEEVQLLDPADAE 542 E +RL + R V RN +D +D E L P + E Sbjct 480 FDEDET---ALRLECIDFARARVLEARNAGRLDGATASLAIKRLDTEGALLAGPIEME 534 >gi|299136008|ref|ZP_07029192.1| Na+/H+ antiporter [Acidobacterium sp. MP5ACTX8] gi|298602132|gb|EFI58286.1| Na+/H+ antiporter [Acidobacterium sp. MP5ACTX8] Length=561 Score = 232 bits (592), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 169/511 (34%), Positives = 273/511 (54%), Gaps = 19/511 (3%) Query 32 LGHRYRVGPPVLLILSGSLLGLIPRFGDVQIDGEVVLLLFLPAILYWESMNTSFREIRWN 91 L R +V P++L+++G L+ IP + ++ ++V L LP +L+ + TS+R+ R+N Sbjct 58 LARRLKVAYPIVLVIAGLLVSFIPGLPKISLNPDMVFLAVLPPLLFHAAWETSWRDFRYN 117 Query 92 LRVIVMFSIGLVIATAVAVSWTARALG--MESHAAAVLGAVLSPTDAAAVAGLAKR--LP 147 + I + GL+ T + V+ L + VLGA+++PTDA A +AKR LP Sbjct 118 IVTIFLMGFGLIGFTVLGVALAGERLFSLLYWRTGFVLGAIVAPTDAIAATSIAKRVGLP 177 Query 148 RRALTVLRGESLINDGTALVL--FAVTVAVAEGAAGIGPAALVGRFVVSYLGGIMAGLLV 205 +R +L GESL+ND T L+ F V + V+ G AL R + + GI G+ V Sbjct 178 QRITDILEGESLVNDATGLLALEFGVAMVVSGTTPSFGAGAL--RLIYLVVAGIGIGVAV 235 Query 206 GGLVTLLRRRIDAPLEEGALSLLTPFAAFLLAQSLKCSGVVAVLVSALVLTYVGPTVIRA 265 G +V ID E L ++T +A+++ A+ SGV+AV+ L L+ + Sbjct 236 GWVVHWFELHIDDGPIEMTLGVVTAYASYIAAEEAHASGVLAVVACGLYLSRKSASFFSP 295 Query 266 RSRLQAHAFWDIATFLINGSLWVFVGVQIPGAIDHIAGEDGGLPRATVL--ALAVTGVVI 323 RLQA+A W+ F++NG ++V +G+Q+P + + + T++ A AV+ +VI Sbjct 296 GVRLQAYALWNAIDFVLNGLVFVLIGLQLPFVLAGLHSYS----KVTLMVDAAAVSALVI 351 Query 324 ATRIAWVQATTVLGHTVDR-VLKKPTRHVGFRQRCVTSWAGFRGAVSLAAALAVPMTTNS 382 A R+ W+ L + + R +LK+ + +Q VT W G RG VSLAAAL++P T + Sbjct 352 ALRLLWIYPGAYLAYFIRRRLLKQDEPMLPAKQIFVTGWTGMRGVVSLAAALSIPETLKN 411 Query 383 GAPFPDRNLIIFVVSVVILVTVLVQGTSLPTVVRWARMPEDVAHANELQLARTRSAQAAL 442 G PFP RNLIIF+ VILVT+++QG +LP +VR + E AR + AL Sbjct 412 GQPFPSRNLIIFLTFSVILVTLVLQGLTLPPLVRALGLGGAGEPDREEGEARRLMLETAL 471 Query 443 DALPTV-ADELGVAPDLVKHLEKEYEERAVLVMADGADSATSDLAERNDLVRRVRLGVLQ 501 + + ++L L L + + ER V+ +D+ T+ A + + V L +L+ Sbjct 472 EHIEEARENDLPEFARLYDDLAEHHRERLAAVLGH-SDTGTN--ARQFARQQAVVLELLK 528 Query 502 HQRQAVTTLRNQNLIDDIVLRELQAAMDLEE 532 QR+ + LR++ I D VLR L+ +DL E Sbjct 529 VQRKILVHLRDEGRISDSVLRRLERELDLNE 559 Lambda K H 0.324 0.138 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1195596576366 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40