BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2300c

Length=310
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609437|ref|NP_216816.1|  hypothetical protein Rv2300c [Mycob...   631    5e-179
gi|289447933|ref|ZP_06437677.1|  conserved hypothetical protein [...   629    2e-178
gi|308232093|ref|ZP_07414890.2|  hypothetical protein TMAG_00488 ...   528    5e-148
gi|289762461|ref|ZP_06521839.1|  conserved hypothetical protein [...   524    7e-147
gi|183983506|ref|YP_001851797.1|  hypothetical protein MMAR_3523 ...   424    1e-116
gi|118618190|ref|YP_906522.1|  hypothetical protein MUL_2742 [Myc...   405    6e-111
gi|296165645|ref|ZP_06848167.1|  beta-lactamase domain protein [M...   394    8e-108
gi|269126579|ref|YP_003299949.1|  beta-lactamase domain-containin...   359    3e-97 
gi|120406026|ref|YP_955855.1|  beta-lactamase domain-containing p...   320    1e-85 
gi|345011587|ref|YP_004813941.1|  hypothetical protein Strvi_4003...   308    7e-82 
gi|329935975|ref|ZP_08285776.1|  hypothetical protein SGM_1268 [S...   308    8e-82 
gi|159035774|ref|YP_001535027.1|  beta-lactamase domain-containin...   304    1e-80 
gi|315442698|ref|YP_004075577.1|  Zn-dependent hydrolase, glyoxyl...   303    2e-80 
gi|290956395|ref|YP_003487577.1|  hypothetical protein SCAB_18881...   303    2e-80 
gi|145222267|ref|YP_001132945.1|  beta-lactamase domain-containin...   303    3e-80 
gi|256378105|ref|YP_003101765.1|  beta-lactamase domain-containin...   286    3e-75 
gi|291301157|ref|YP_003512435.1|  beta-lactamase domain-containin...   260    2e-67 
gi|343928512|ref|ZP_08767959.1|  hypothetical protein GOALK_118_0...   234    2e-59 
gi|226362805|ref|YP_002780583.1|  hypothetical protein ROP_33910 ...   232    4e-59 
gi|292492929|ref|YP_003528368.1|  beta-lactamase [Nitrosococcus h...   218    9e-55 
gi|335423974|ref|ZP_08552992.1|  beta-lactamase [Salinisphaera sh...   216    5e-54 
gi|300868753|ref|ZP_07113364.1|  Beta-lactamase domain protein [O...   205    8e-51 
gi|149926911|ref|ZP_01915170.1|  hypothetical protein LMED105_129...   204    1e-50 
gi|334118604|ref|ZP_08492693.1|  beta-lactamase domain protein [M...   201    1e-49 
gi|333919023|ref|YP_004492604.1|  beta-lactamase class B [Amycoli...   200    3e-49 
gi|29827758|ref|NP_822392.1|  metallo-beta-lactamase [Streptomyce...   200    3e-49 
gi|302530500|ref|ZP_07282842.1|  metallo-beta-lactamase [Streptom...   199    4e-49 
gi|27378189|ref|NP_769718.1|  hypothetical protein blr3078 [Brady...   197    3e-48 
gi|300790245|ref|YP_003770536.1|  beta-lactamase class B [Amycola...   195    6e-48 
gi|338531343|ref|YP_004664677.1|  metallo-beta-lactamase family p...   194    1e-47 
gi|319948139|ref|ZP_08022302.1|  beta-lactamase domain protein [D...   192    6e-47 
gi|115372222|ref|ZP_01459532.1|  metallo-beta-lactamase superfami...   191    1e-46 
gi|209516791|ref|ZP_03265642.1|  beta-lactamase domain protein [B...   191    1e-46 
gi|295681169|ref|YP_003609743.1|  metallo-beta-lactamase superfam...   191    1e-46 
gi|300790244|ref|YP_003770535.1|  beta-lactamase class B [Amycola...   189    5e-46 
gi|134098838|ref|YP_001104499.1|  metallo-beta-lactamase [Sacchar...   189    6e-46 
gi|186681285|ref|YP_001864481.1|  beta-lactamase domain-containin...   187    1e-45 
gi|255318709|ref|ZP_05359936.1|  metallo-beta-lactamase family pr...   187    2e-45 
gi|262378110|ref|ZP_06071267.1|  metallo-beta-lactamase superfami...   187    3e-45 
gi|332185382|ref|ZP_08387130.1|  metallo-beta-lactamase superfami...   187    3e-45 
gi|294624701|ref|ZP_06703369.1|  metallo-beta-lactamase superfami...   184    1e-44 
gi|294665924|ref|ZP_06731190.1|  metallo-beta-lactamase superfami...   184    2e-44 
gi|108758299|ref|YP_628344.1|  metallo-beta-lactamase family prot...   184    2e-44 
gi|260596820|ref|YP_003209391.1|  hypothetical protein CTU_10280 ...   183    4e-44 
gi|221197486|ref|ZP_03570533.1|  metallo-beta-lactamase superfami...   182    4e-44 
gi|221210586|ref|ZP_03583566.1|  metallo-beta-lactamase superfami...   182    5e-44 
gi|308185502|ref|YP_003929634.1|  hypothetical protein Pvag_pPag1...   181    1e-43 
gi|78048122|ref|YP_364297.1|  metallo-beta-lactamase superfamily ...   181    2e-43 
gi|21108618|gb|AAM37220.1|  conserved hypothetical protein [Xanth...   181    2e-43 
gi|337279707|ref|YP_004619179.1|  hypothetical protein Rta_20670 ...   179    3e-43 


>gi|15609437|ref|NP_216816.1| hypothetical protein Rv2300c [Mycobacterium tuberculosis H37Rv]
 gi|15841791|ref|NP_336828.1| hypothetical protein MT2357 [Mycobacterium tuberculosis CDC1551]
 gi|31793478|ref|NP_855971.1| hypothetical protein Mb2322c [Mycobacterium bovis AF2122/97]
 51 more sequence titles
 Length=310

 Score =  631 bits (1627),  Expect = 5e-179, Method: Compositional matrix adjust.
 Identities = 310/310 (100%), Positives = 310/310 (100%), Gaps = 0/310 (0%)

Query  1    MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGT  60
            MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGT
Sbjct  1    MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGT  60

Query  61   MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI  120
            MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI
Sbjct  61   MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI  120

Query  121  EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ  180
            EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ
Sbjct  121  EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ  180

Query  181  WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC  240
            WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC
Sbjct  181  WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC  240

Query  241  GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDP  300
            GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDP
Sbjct  241  GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDP  300

Query  301  DLYQLARDTA  310
            DLYQLARDTA
Sbjct  301  DLYQLARDTA  310


>gi|289447933|ref|ZP_06437677.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
 gi|289420891|gb|EFD18092.1| conserved hypothetical protein [Mycobacterium tuberculosis CPHL_A]
Length=310

 Score =  629 bits (1622),  Expect = 2e-178, Method: Compositional matrix adjust.
 Identities = 309/310 (99%), Positives = 309/310 (99%), Gaps = 0/310 (0%)

Query  1    MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGT  60
            MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPV VHHLNCGT
Sbjct  1    MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVMVHHLNCGT  60

Query  61   MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI  120
            MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI
Sbjct  61   MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI  120

Query  121  EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ  180
            EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ
Sbjct  121  EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ  180

Query  181  WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC  240
            WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC
Sbjct  181  WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC  240

Query  241  GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDP  300
            GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDP
Sbjct  241  GDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDP  300

Query  301  DLYQLARDTA  310
            DLYQLARDTA
Sbjct  301  DLYQLARDTA  310


>gi|308232093|ref|ZP_07414890.2| hypothetical protein TMAG_00488 [Mycobacterium tuberculosis SUMu001]
 gi|308369682|ref|ZP_07418669.2| hypothetical protein TMBG_00845 [Mycobacterium tuberculosis SUMu002]
 gi|308370968|ref|ZP_07423399.2| hypothetical protein TMCG_00394 [Mycobacterium tuberculosis SUMu003]
 24 more sequence titles
 Length=260

 Score =  528 bits (1359),  Expect = 5e-148, Method: Compositional matrix adjust.
 Identities = 259/260 (99%), Positives = 260/260 (100%), Gaps = 0/260 (0%)

Query  51   VKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAF  110
            +KVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAF
Sbjct  1    MKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAF  60

Query  111  LQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSL  170
            LQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSL
Sbjct  61   LQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSL  120

Query  171  RERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAV  230
            RERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAV
Sbjct  121  RERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAV  180

Query  231  DAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDP  290
            DAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDP
Sbjct  181  DAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDP  240

Query  291  DLLIVCAHDPDLYQLARDTA  310
            DLLIVCAHDPDLYQLARDTA
Sbjct  241  DLLIVCAHDPDLYQLARDTA  260


>gi|289762461|ref|ZP_06521839.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
 gi|289709967|gb|EFD73983.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
Length=269

 Score =  524 bits (1349),  Expect = 7e-147, Method: Compositional matrix adjust.
 Identities = 257/258 (99%), Positives = 257/258 (99%), Gaps = 0/258 (0%)

Query  1    MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGT  60
            MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGT
Sbjct  1    MVATRGRPCPTNFSRPQRPRVAGNGTKSQRCRGRLTTSMLGVAPEAKGPPVKVHHLNCGT  60

Query  61   MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI  120
            MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI
Sbjct  61   MNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAFLQAETAARQI  120

Query  121  EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ  180
            EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ
Sbjct  121  EQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQ  180

Query  181  WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC  240
            WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC
Sbjct  181  WAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHC  240

Query  241  GDAFYHRGTLDGRFRVPF  258
            GDAFYHRGTLDGRFRVP 
Sbjct  241  GDAFYHRGTLDGRFRVPL  258


>gi|183983506|ref|YP_001851797.1| hypothetical protein MMAR_3523 [Mycobacterium marinum M]
 gi|183176832|gb|ACC41942.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=260

 Score =  424 bits (1089),  Expect = 1e-116, Method: Compositional matrix adjust.
 Identities = 201/260 (78%), Positives = 228/260 (88%), Gaps = 0/260 (0%)

Query  51   VKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAF  110
            +KVHHLNCGTMN+ G ALLCHVLLVE  +GLVLVDTGFG+QDCLDP R+G FRH LRPA 
Sbjct  1    MKVHHLNCGTMNSPGAALLCHVLLVEAGNGLVLVDTGFGVQDCLDPRRLGAFRHFLRPAL  60

Query  111  LQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSL  170
            LQ ETA  QIE+LGYR SDVRH+VLTHFDFDHIGG+ADFP+A +HVT+AEARGAIHAPS 
Sbjct  61   LQNETAVHQIERLGYRPSDVRHVVLTHFDFDHIGGLADFPDAQVHVTSAEARGAIHAPSF  120

Query  171  RERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAV  230
            RER+RYR  QWAHGPKLVEHG DGE WRGFA+AKPLD+I  GVVLVPMPGHTRGHAAVAV
Sbjct  121  RERVRYRSVQWAHGPKLVEHGHDGESWRGFAAAKPLDAIADGVVLVPMPGHTRGHAAVAV  180

Query  231  DAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDP  290
            DAG RW+LHCGDAFYH GTLDG+ +VPFV+R++E+L S++R QLRDNQAR+ EL RR DP
Sbjct  181  DAGDRWILHCGDAFYHVGTLDGQSKVPFVLRSQEELFSFDRRQLRDNQARLAELQRRQDP  240

Query  291  DLLIVCAHDPDLYQLARDTA  310
             LLI+CAHDP LY LA+D +
Sbjct  241  GLLIICAHDPSLYALAKDLS  260


>gi|118618190|ref|YP_906522.1| hypothetical protein MUL_2742 [Mycobacterium ulcerans Agy99]
 gi|118570300|gb|ABL05051.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99]
Length=260

 Score =  405 bits (1040),  Expect = 6e-111, Method: Compositional matrix adjust.
 Identities = 195/260 (75%), Positives = 222/260 (86%), Gaps = 0/260 (0%)

Query  51   VKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPAF  110
            +KVHH NCGTMN+ G ALLCHVLLVE  +GLVLVDTGFG+QDCLD  R+G FRH LRPA 
Sbjct  1    MKVHHHNCGTMNSPGAALLCHVLLVEAGNGLVLVDTGFGVQDCLDQRRLGAFRHFLRPAL  60

Query  111  LQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSL  170
            LQ ETA  QIE+LGYR SDVRHIVLTHFD DHIGG+ADFP+A +HVT+AEARGAIHAPS 
Sbjct  61   LQNETAVHQIERLGYRPSDVRHIVLTHFDSDHIGGLADFPDAQVHVTSAEARGAIHAPSF  120

Query  171  RERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAV  230
            RER+RYR  QWAHGPKLVEHG DGE   GFA+AK LD+I  GVVLVPMPGHTRGHAAVAV
Sbjct  121  RERVRYRSVQWAHGPKLVEHGHDGESSPGFAAAKTLDAIADGVVLVPMPGHTRGHAAVAV  180

Query  231  DAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDP  290
            DAG RW+LHCGDAFYH GTLDG+ +VPFV+R++E+L S++R QLRDNQAR+ EL RR DP
Sbjct  181  DAGDRWILHCGDAFYHVGTLDGQSKVPFVLRSQEELFSFDRRQLRDNQARLAELQRRQDP  240

Query  291  DLLIVCAHDPDLYQLARDTA  310
             LLI+CAHDP LY +A+D +
Sbjct  241  GLLIICAHDPSLYAVAKDLS  260


>gi|296165645|ref|ZP_06848167.1| beta-lactamase domain protein [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295899016|gb|EFG78500.1| beta-lactamase domain protein [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=265

 Score =  394 bits (1013),  Expect = 8e-108, Method: Compositional matrix adjust.
 Identities = 191/261 (74%), Positives = 216/261 (83%), Gaps = 1/261 (0%)

Query  51   VKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPG-RVGLFRHVLRPA  109
            +KVHHLNCGTM   G+AL+CHVLLVETD+GLVLVD+GFG  DC DP  R+G+FRHV+RP 
Sbjct  1    MKVHHLNCGTMRMPGVALVCHVLLVETDNGLVLVDSGFGSHDCHDPAARIGVFRHVIRPL  60

Query  110  FLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPS  169
               AETAA QI  LG+  +DVRHIVLTH D DHIGG+ADFP AH+H+TAAEARGAIHAP+
Sbjct  61   LQHAETAADQITALGFNVADVRHIVLTHLDLDHIGGLADFPHAHVHLTAAEARGAIHAPT  120

Query  170  LRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVA  229
             RER RYR  QWAH P LVEH PDGEPWRGF +AKPL  I  G+VLVPMPGHTRGH AVA
Sbjct  121  WRERFRYRPTQWAHRPTLVEHTPDGEPWRGFTAAKPLHVIDDGIVLVPMPGHTRGHTAVA  180

Query  230  VDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHD  289
            VDAGHRWVLH GDAFYH GTLD + RVPFV+RA+E L+ Y+RN LRDNQ+R+ EL+ R D
Sbjct  181  VDAGHRWVLHAGDAFYHPGTLDHQSRVPFVLRAQETLICYDRNTLRDNQSRLAELYHRRD  240

Query  290  PDLLIVCAHDPDLYQLARDTA  310
            PDLLIVC+HDP LYQ ARDTA
Sbjct  241  PDLLIVCSHDPSLYQHARDTA  261


>gi|269126579|ref|YP_003299949.1| beta-lactamase domain-containing protein [Thermomonospora curvata 
DSM 43183]
 gi|268311537|gb|ACY97911.1| beta-lactamase domain protein [Thermomonospora curvata DSM 43183]
Length=261

 Score =  359 bits (922),  Expect = 3e-97, Method: Compositional matrix adjust.
 Identities = 170/258 (66%), Positives = 210/258 (82%), Gaps = 1/258 (0%)

Query  51   VKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGR-VGLFRHVLRPA  109
            +KVHHLNCG+M   G  L+CHVLLVETD GLVLVDTGFG+QD  DP R +GL RH++RP 
Sbjct  1    MKVHHLNCGSMRPLGGPLVCHVLLVETDSGLVLVDTGFGLQDVADPARRLGLTRHLIRPV  60

Query  110  FLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPS  169
                ETAARQ+E+LG+R  DVRHI+LTHFD DHIGG+ADFP A +HVTAAEA GA+ +P+
Sbjct  61   LDPEETAARQVERLGFRRRDVRHILLTHFDMDHIGGLADFPHAQVHVTAAEAEGAMRSPT  120

Query  170  LRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVA  229
              ER RYR  QWAHGP++VEH P GE WRGFA+A+PL++I  G+VL+P+PGHTRGHA VA
Sbjct  121  WAERRRYRPVQWAHGPRIVEHSPHGESWRGFAAARPLEAIAPGLVLIPLPGHTRGHACVA  180

Query  230  VDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHD  289
            VDAG RWVLHCGDAFYHRGT+DGR RVPF +RA E L++++R ++  N AR+ EL+RR +
Sbjct  181  VDAGDRWVLHCGDAFYHRGTVDGRSRVPFPLRAMESLVAFDRGKVHSNHARLAELYRRAE  240

Query  290  PDLLIVCAHDPDLYQLAR  307
            PDL++VCAHDP +Y+  R
Sbjct  241  PDLVVVCAHDPVMYEAMR  258


>gi|120406026|ref|YP_955855.1| beta-lactamase domain-containing protein [Mycobacterium vanbaalenii 
PYR-1]
 gi|119958844|gb|ABM15849.1| beta-lactamase domain protein [Mycobacterium vanbaalenii PYR-1]
Length=264

 Score =  320 bits (821),  Expect = 1e-85, Method: Compositional matrix adjust.
 Identities = 158/262 (61%), Positives = 197/262 (76%), Gaps = 2/262 (0%)

Query  51   VKVHHLNCGTMNAFGI-ALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRH-VLRP  108
            +KVHHLNCGT+   G+  ++CHVLLVE+ DGLVLVDTGFG  DC DP R G  R   +RP
Sbjct  1    MKVHHLNCGTIRPTGVGTMVCHVLLVESADGLVLVDTGFGTHDCEDPNRFGRIRSRFIRP  60

Query  109  AFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAP  168
             F + ETA  QI QLG+R SDVRH+V+THFD DHIGG+ADFP+A +HVT  EA GA+ +P
Sbjct  61   NFDRGETALNQIRQLGFRRSDVRHVVVTHFDADHIGGLADFPDALVHVTTTEAFGAMRSP  120

Query  169  SLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAV  228
            S++ER+R+R  QWAHGP++VEH  DGE WRGFA+AK L  IG G VLV +PGHTRGHA V
Sbjct  121  SIQERIRFRPPQWAHGPRIVEHDIDGEAWRGFAAAKELTQIGPGFVLVSLPGHTRGHACV  180

Query  229  AVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRH  288
            AVDAGHRW+LH GD+FYH GTL G   VP      E L++ ++ +++ N  R+ EL+RR 
Sbjct  181  AVDAGHRWLLHAGDSFYHPGTLAGAPPVPKWTARLEMLVASDKQKVKQNHVRLAELYRRQ  240

Query  289  DPDLLIVCAHDPDLYQLARDTA  310
            DPDL+I+C+HD  LY+ AR TA
Sbjct  241  DPDLMILCSHDVTLYEQARATA  262


>gi|345011587|ref|YP_004813941.1| hypothetical protein Strvi_4003 [Streptomyces violaceusniger 
Tu 4113]
 gi|344037936|gb|AEM83661.1| hypothetical protein Strvi_4003 [Streptomyces violaceusniger 
Tu 4113]
Length=265

 Score =  308 bits (789),  Expect = 7e-82, Method: Compositional matrix adjust.
 Identities = 152/255 (60%), Positives = 185/255 (73%), Gaps = 1/255 (0%)

Query  51   VKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGR-VGLFRHVLRPA  109
            ++VHHLNCGTM   G  L+CHVL VET +GLVLVD+G+G QD  +P R VG  RH++RPA
Sbjct  1    MRVHHLNCGTMRLPGADLVCHVLAVETSNGLVLVDSGYGTQDIAEPARRVGPVRHIVRPA  60

Query  110  FLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPS  169
            F   ETA  QI++LG++  DV HIV THFD DHIGG++DFP+A +HVT+AE RGA+   +
Sbjct  61   FDVRETALHQIKELGFQAEDVSHIVTTHFDLDHIGGLSDFPDAQVHVTSAEVRGALSPAT  120

Query  170  LRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVA  229
              ER RYR    +H PKLVEH P G+ WRGF +AK L  I  G+VLVPMPGHTRGHAAVA
Sbjct  121  RLERGRYRHILLSHRPKLVEHDPTGDQWRGFTAAKQLTEIDDGIVLVPMPGHTRGHAAVA  180

Query  230  VDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHD  289
            VD G  WVLHCGD FYH GTLDG  RVP  +R +E+L+++N   LR NQ RI EL     
Sbjct  181  VDTGDYWVLHCGDTFYHPGTLDGTSRVPASLRVQERLVAHNVKALRANQERIAELREGDQ  240

Query  290  PDLLIVCAHDPDLYQ  304
              L++VCAHDP L+Q
Sbjct  241  EHLMVVCAHDPSLFQ  255


>gi|329935975|ref|ZP_08285776.1| hypothetical protein SGM_1268 [Streptomyces griseoaurantiacus 
M045]
 gi|329304582|gb|EGG48459.1| hypothetical protein SGM_1268 [Streptomyces griseoaurantiacus 
M045]
Length=265

 Score =  308 bits (789),  Expect = 8e-82, Method: Compositional matrix adjust.
 Identities = 161/262 (62%), Positives = 195/262 (75%), Gaps = 3/262 (1%)

Query  51   VKVHHLNCGTMNAFGIALLCHVLLVETDD-GLVLVDTGFGIQDCLDPGR-VGLFRHVLRP  108
            +KVHHLNCGTM   G AL+CHVLLVETD  GLVLVD+G+G++D  +P R VG  R  +RP
Sbjct  1    MKVHHLNCGTMRPPGAALVCHVLLVETDRRGLVLVDSGYGLRDVAEPARRVGPLRLAMRP  60

Query  109  AFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAP  168
                 ETAARQ+E+LG+R  DVRHIVLTH D DH+GGIADFP A +HVTAAEARGAIHAP
Sbjct  61   LLDPEETAARQVERLGFRREDVRHIVLTHLDPDHVGGIADFPGARVHVTAAEARGAIHAP  120

Query  169  SLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAV  228
            + RERLR+R  QW HGP LVEHGP GE W GFA+A+ LD +  G+VLVP+PGHTRGHA V
Sbjct  121  TRRERLRFRPAQWDHGPLLVEHGPGGEAWHGFAAARELDEVAPGIVLVPLPGHTRGHAGV  180

Query  229  AVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRH  288
            AV+A    +LH GDAF+HR TL GR R+P  +RA E L++++  ++R N  R+ ELH R 
Sbjct  181  AVEAEDGVLLHAGDAFFHRTTLSGRTRMPLALRATETLVAHDLARVRANHDRLAELHGRA  240

Query  289  DPDLLIVCAHDPDLYQLARDTA  310
            D    I+CAHDP L   AR+ A
Sbjct  241  D-GPAILCAHDPVLLARARNGA  261


>gi|159035774|ref|YP_001535027.1| beta-lactamase domain-containing protein [Salinispora arenicola 
CNS-205]
 gi|157914609|gb|ABV96036.1| beta-lactamase domain protein [Salinispora arenicola CNS-205]
Length=261

 Score =  304 bits (778),  Expect = 1e-80, Method: Compositional matrix adjust.
 Identities = 149/254 (59%), Positives = 193/254 (76%), Gaps = 1/254 (0%)

Query  51   VKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGR-VGLFRHVLRPA  109
            +KVHHLNCG++  F   L+CHVLLVET++GLVLVDTG+G+ D  DP R +G  R ++RP 
Sbjct  1    MKVHHLNCGSIRVFREPLVCHVLLVETNNGLVLVDTGYGLDDIADPRRRIGPTRTIVRPV  60

Query  110  FLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPS  169
                ETAARQ+E+LG+R  DVRHIV+THFD DHIGG++DFP A +H TA E RGA + P+
Sbjct  61   LDPDETAARQVERLGFRRDDVRHIVVTHFDADHIGGLSDFPHAAVHTTADEVRGARNPPT  120

Query  170  LRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVA  229
             RER R+R  QW HGP+++EHG  GEPWRGFA+ KPLD I  G VL+P+PGHTRGHA VA
Sbjct  121  WRERSRFRPAQWRHGPRIIEHGAAGEPWRGFAAVKPLDEIAPGFVLIPLPGHTRGHACVA  180

Query  230  VDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHD  289
            VDAG +W+LH GDAFYH G++DG   VPFV+RA E L++++R ++R+N AR+  +  R +
Sbjct  181  VDAGEQWLLHAGDAFYHPGSIDGGGGVPFVLRAMETLVAFDRRRVRENHARLAAVRARAE  240

Query  290  PDLLIVCAHDPDLY  303
            PDL +  AHDP  +
Sbjct  241  PDLTLFSAHDPAAF  254


>gi|315442698|ref|YP_004075577.1| Zn-dependent hydrolase, glyoxylase [Mycobacterium sp. Spyr1]
 gi|315261001|gb|ADT97742.1| Zn-dependent hydrolase, glyoxylase [Mycobacterium sp. Spyr1]
Length=267

 Score =  303 bits (776),  Expect = 2e-80, Method: Compositional matrix adjust.
 Identities = 151/265 (57%), Positives = 193/265 (73%), Gaps = 5/265 (1%)

Query  51   VKVHHLNCGTMNAFGIA--LLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLR-  107
            +KV HLNCGT+    +   ++CHVLLVE+D GLVLVD+GFG +DC  P   G  R  +  
Sbjct  1    MKVRHLNCGTIRPVKVPVPMVCHVLLVESDAGLVLVDSGFGTRDCAHPEEFGRIRRRIIR  60

Query  108  PAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHA  167
            P F + ETAA Q+ +LGYR SDVRHI++THFD DHIGG+ADFP+A +HVTA E   A+ +
Sbjct  61   PDFERTETAAEQLTRLGYRPSDVRHIIVTHFDADHIGGLADFPDAQVHVTAQEVLSAMKS  120

Query  168  PSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAA  227
            PS++ R+R++  QWAHGP++VEH  DGEPWRGFA+AK L  IG G  LVP+PGHT GHA 
Sbjct  121  PSVQNRIRFQPSQWAHGPRIVEHTADGEPWRGFAAAKELSEIGPGFALVPLPGHTEGHAC  180

Query  228  VAVDAGHRWVLHCGDAFYHRGTLDGRF--RVPFVMRAEEKLLSYNRNQLRDNQARIVELH  285
            VAVDAGHRW+LH GDAFYH   +DG     +P  +RA E  ++ +R  + DN +R+ EL+
Sbjct  181  VAVDAGHRWLLHAGDAFYHHSEIDGGGPPPMPASLRAFEMAVAADRKMVLDNHSRLTELY  240

Query  286  RRHDPDLLIVCAHDPDLYQLARDTA  310
            RR DPDLLIVC+HD  LY+ A+ TA
Sbjct  241  RRQDPDLLIVCSHDRKLYEHAKATA  265


>gi|290956395|ref|YP_003487577.1| hypothetical protein SCAB_18881 [Streptomyces scabiei 87.22]
 gi|260645921|emb|CBG69012.1| CONSERVED HYPOTHETICAL PROTEIN [Streptomyces scabiei 87.22]
Length=261

 Score =  303 bits (776),  Expect = 2e-80, Method: Compositional matrix adjust.
 Identities = 158/262 (61%), Positives = 192/262 (74%), Gaps = 3/262 (1%)

Query  51   VKVHHLNCGTM-NAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLRPA  109
            +KVHHLNCGTM      AL+CHVLLVE   GLVLVD+GFG++D  DP         L   
Sbjct  1    MKVHHLNCGTMVPPLTGALVCHVLLVEAPGGLVLVDSGFGLRDVADPRGRLGRDRRLLRP  60

Query  110  FLQAE-TAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAP  168
             L+AE TAARQ+E LG+R  DVRH+V+THFD DHIGG+ADFP+A +H TAAE  G++ +P
Sbjct  61   VLRAEETAARQVEALGFRRDDVRHVVVTHFDLDHIGGLADFPDAQVHTTAAEVLGSMVSP  120

Query  169  SLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAV  228
            S RER RYR  QWAHGPK+VEH PDGE WRGFA+A+ LD++  G+VL+ +PGHTRGHA V
Sbjct  121  SRRERSRYRPVQWAHGPKIVEHTPDGEAWRGFAAARELDAVAPGIVLISLPGHTRGHACV  180

Query  229  AVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRH  288
            AVD G RW+LH GDAF+HR TLDG   VP  +R  E LL+ +R ++RDN AR+ ELH R 
Sbjct  181  AVDTGPRWILHAGDAFFHRATLDGH-PVPRTLRTVETLLADDRGRVRDNHARLAELHGRD  239

Query  289  DPDLLIVCAHDPDLYQLARDTA  310
            DP L +V AHDP L + AR TA
Sbjct  240  DPGLSVVNAHDPVLLERARATA  261


>gi|145222267|ref|YP_001132945.1| beta-lactamase domain-containing protein [Mycobacterium gilvum 
PYR-GCK]
 gi|145214753|gb|ABP44157.1| beta-lactamase domain protein [Mycobacterium gilvum PYR-GCK]
Length=267

 Score =  303 bits (775),  Expect = 3e-80, Method: Compositional matrix adjust.
 Identities = 151/265 (57%), Positives = 192/265 (73%), Gaps = 5/265 (1%)

Query  51   VKVHHLNCGTMNAFGIA--LLCHVLLVETDDGLVLVDTGFGIQDCLDPGRVGLFRHVLR-  107
            +KV HLNCGT+    +   ++CHVLLVE+D GLVLVD+GFG +DC  P   G  R  +  
Sbjct  1    MKVRHLNCGTIRPVKVPVPMVCHVLLVESDAGLVLVDSGFGTRDCAHPEEFGRIRRRIIR  60

Query  108  PAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHA  167
            P F + ETAA Q+  LGYR SDVRHI++THFD DHIGG+ADFP+A +HVTA E   A+ +
Sbjct  61   PDFERTETAAEQLAHLGYRLSDVRHIIVTHFDADHIGGLADFPDAQVHVTAQEVLSAMKS  120

Query  168  PSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAA  227
            PS++ R+R++  QWAHGP++VEH  DGEPWRGFA+AK L  IG G  LVP+PGHT GHA 
Sbjct  121  PSVQNRIRFQPSQWAHGPRIVEHTADGEPWRGFAAAKELSEIGPGFALVPLPGHTEGHAC  180

Query  228  VAVDAGHRWVLHCGDAFYHRGTLDGRF--RVPFVMRAEEKLLSYNRNQLRDNQARIVELH  285
            VAVDAGHRW+LH GDAFYH   +DG     +P  +RA E  ++ +R  + DN +R+ EL+
Sbjct  181  VAVDAGHRWLLHAGDAFYHHSEIDGGGPPPMPASLRAFEMAVAADRKMVLDNHSRLTELY  240

Query  286  RRHDPDLLIVCAHDPDLYQLARDTA  310
            RR DPDLLIVC+HD  LY+ A+ TA
Sbjct  241  RRQDPDLLIVCSHDRKLYEHAKATA  265


>gi|256378105|ref|YP_003101765.1| beta-lactamase domain-containing protein [Actinosynnema mirum 
DSM 43827]
 gi|255922408|gb|ACU37919.1| beta-lactamase domain protein [Actinosynnema mirum DSM 43827]
Length=258

 Score =  286 bits (731),  Expect = 3e-75, Method: Compositional matrix adjust.
 Identities = 142/258 (56%), Positives = 178/258 (69%), Gaps = 1/258 (0%)

Query  51   VKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDPGR-VGLFRHVLRPA  109
            ++VHHLNCGTM   G  ++ HVLL+ET  GL LVDTG+G+ D   P R +G +RHV+RP 
Sbjct  1    MRVHHLNCGTMRLPGARVVTHVLLLETPTGLALVDTGYGVADIAAPARRLGAYRHVVRPV  60

Query  110  FLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPS  169
              +AETA  Q+  LG+   DVR +V+THFD DH+GG+ADFP A +HVTA E   A    +
Sbjct  61   LDRAETAVEQVRGLGFAPEDVRDVVVTHFDTDHVGGLADFPWARVHVTATEWEAASRPRT  120

Query  170  LRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVA  229
              ER RYR  QW HGP++  HGP GE WRGFA+A+ L  +  GVVLVP+PGHTRGHAAVA
Sbjct  121  ALERARYRSAQWEHGPQIAAHGPGGESWRGFAAARELTDVAPGVVLVPLPGHTRGHAAVA  180

Query  230  VDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHD  289
            VDAG RWVLH GDAFY    L G  + P  +RA+E+ ++++R  LR NQ R+ ELHR+  
Sbjct  181  VDAGSRWVLHAGDAFYDLRALTGGVKPPAALRAQERAVAHDRGSLRANQERLAELHRQGQ  240

Query  290  PDLLIVCAHDPDLYQLAR  307
             DLL+V AHDP     AR
Sbjct  241  QDLLLVNAHDPAPLAAAR  258


>gi|291301157|ref|YP_003512435.1| beta-lactamase domain-containing protein [Stackebrandtia nassauensis 
DSM 44728]
 gi|290570377|gb|ADD43342.1| beta-lactamase domain protein [Stackebrandtia nassauensis DSM 
44728]
Length=253

 Score =  260 bits (665),  Expect = 2e-67, Method: Compositional matrix adjust.
 Identities = 137/251 (55%), Positives = 172/251 (69%), Gaps = 4/251 (1%)

Query  61   MNAFGI--ALLCHVLLVETDDGLVLVDTGFGIQDCLDPG-RVGLFRHVLRPAFLQAETAA  117
            M+ FG+   L+CHVLL+ETD GL LVD GFG  D   P  R G  RH +RPAF +AETA 
Sbjct  1    MSPFGVPDGLVCHVLLLETDTGLALVDCGFGTLDIASPAKRCGPIRHFIRPAFDEAETAI  60

Query  118  RQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYR  177
            RQ+E+LG+R SDVR IV+THFD DH+GG++DFP A +HVTA EA GA+   +L E+ RYR
Sbjct  61   RQVERLGHRPSDVRDIVVTHFDADHVGGLSDFPWARVHVTADEAAGALRPVTLLEKRRYR  120

Query  178  RGQWAHGPKLVEHGP-DGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRW  236
              Q  HGP+LV H P + E WRGF   K L  I  G+VL+ +PGHTRGHAAVAVDAG  W
Sbjct  121  SAQRDHGPELVPHTPGEKESWRGFTGVKELTEIAPGIVLISLPGHTRGHAAVAVDAGDHW  180

Query  237  VLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVC  296
            VLH GD+FYHR  L    R P  +R  E+ ++++R++L  N AR+ EL    +P L++V 
Sbjct  181  VLHVGDSFYHRSQLGSAKRPPVSLRVLERAVAFDRDRLGANLARLTELWNDSEPGLVLVN  240

Query  297  AHDPDLYQLAR  307
            AHDP L   AR
Sbjct  241  AHDPTLLHRAR  251


>gi|343928512|ref|ZP_08767959.1| hypothetical protein GOALK_118_00030 [Gordonia alkanivorans NBRC 
16433]
 gi|343761523|dbj|GAA14885.1| hypothetical protein GOALK_118_00030 [Gordonia alkanivorans NBRC 
16433]
Length=263

 Score =  234 bits (596),  Expect = 2e-59, Method: Compositional matrix adjust.
 Identities = 129/264 (49%), Positives = 163/264 (62%), Gaps = 5/264 (1%)

Query  51   VKVHHLNCGTMNAFGI--ALLCHVLLVETDDGLVLVDTGFGIQDCLD-PGRVGLFRHVLR  107
            +KVHHLNCGTM  +     L+CHVLL+ET +GL LVD+GFG+ D      R+G  RH +R
Sbjct  1    MKVHHLNCGTMRPWATPDGLVCHVLLIETANGLALVDSGFGLADGPQRKTRMGSARHYVR  60

Query  108  PAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHA  167
            P F   ETA RQ+  LGY  +DVR IVLTHFD DHIGG++DFP A +H+TAAE       
Sbjct  61   PVFDPDETAIRQLTSLGYEPTDVRDIVLTHFDADHIGGLSDFPWARVHLTAAEIHAVQAR  120

Query  168  PSLRERLRYRRGQWAHGPKLVEHGP-DGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHA  226
             +  ER RY  G       +V H P  GE W G  +   L  I  GV+LV +PGH+RGHA
Sbjct  121  ETFVERRRYHPGA-IDEVDVVAHSPVAGEKWHGLDAVIELSEISAGVLLVALPGHSRGHA  179

Query  227  AVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARIVELHR  286
            AVAV AG RWV+H GD+FYH G +DG    P  + A E++++ +  ++  N  R+ EL  
Sbjct  180  AVAVQAGDRWVIHVGDSFYHHGQIDGTGHAPLALTAMERVIARDWRKVVSNHRRLSELWA  239

Query  287  RHDPDLLIVCAHDPDLYQLARDTA  310
              DP L IV AHDP L  LAR  +
Sbjct  240  AGDPQLTIVNAHDPHLLALARQAS  263


>gi|226362805|ref|YP_002780583.1| hypothetical protein ROP_33910 [Rhodococcus opacus B4]
 gi|226241290|dbj|BAH51638.1| hypothetical protein [Rhodococcus opacus B4]
Length=269

 Score =  232 bits (592),  Expect = 4e-59, Method: Compositional matrix adjust.
 Identities = 123/262 (47%), Positives = 168/262 (65%), Gaps = 8/262 (3%)

Query  51   VKVHHLNCGTMNAFGIA-LLCHVLLVETDDGLVLVDTGFGIQDCLDP-GRVGLFRHVLRP  108
            ++VHHLNCG+ ++  I  L+CHVL  ETD G+VLVD+GFG+ D  DP GRVG +  +   
Sbjct  1    MRVHHLNCGSFSSALIGRLVCHVLACETDAGIVLVDSGFGLADVADPAGRVGKYAKLTGA  60

Query  109  AFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAP  168
             F ++ETA RQ+ +LG   SDV HIV TH DFDHIGG+ADFP A LH TAAE   +    
Sbjct  61   RFRESETAVRQLGKLGLNPSDVTHIVATHLDFDHIGGVADFPNATLHTTAAEVAASDKRS  120

Query  169  SLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAV  228
            S RE++RYR  Q    P +  +   GE   GF+   P+  +G  +VLVP+PGHT GHAAV
Sbjct  121  SFREKVRYRPAQLTPAPTVHTYSGPGESVLGFSDTYPIAGVGDRIVLVPLPGHTWGHAAV  180

Query  229  AVDAGHR-WVLHCGDAFYHRGTLDGRFRVP-----FVMRAEEKLLSYNRNQLRDNQARIV  282
            AVD G + W+LH GDAFYHR T+    +V        +R  E+L++ +R+++R N  R+ 
Sbjct  181  AVDTGEKGWLLHAGDAFYHRSTVAAPGQVSPGTEGRALRVMEELIAVDRSKIRGNHRRLR  240

Query  283  ELHRRHDPDLLIVCAHDPDLYQ  304
            EL+ +  P + +  AHDP L++
Sbjct  241  ELNNQVAPRVRVFSAHDPTLFE  262


>gi|292492929|ref|YP_003528368.1| beta-lactamase [Nitrosococcus halophilus Nc4]
 gi|291581524|gb|ADE15981.1| beta-lactamase domain protein [Nitrosococcus halophilus Nc4]
Length=274

 Score =  218 bits (555),  Expect = 9e-55, Method: Compositional matrix adjust.
 Identities = 114/264 (44%), Positives = 159/264 (61%), Gaps = 15/264 (5%)

Query  51   VKVHHLNCGTMNAFG------------IALLCHVLLVETDDGLVLVDTGFGIQDCLDPG-  97
            + +HHLNCGTM  FG              L+CH LL+ET  GLVL+DTGFG+QD  +   
Sbjct  2    ITIHHLNCGTMCPFGGRFIDGFSRGLTAKLVCHCLLIETKAGLVLIDTGFGLQDIRNAHH  61

Query  98   RVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHV  156
            R+G +F  ++     + +TA RQIE+LG++  DVRHI+LTH DFDH GGI DFPEA +HV
Sbjct  62   RLGRIFLKLIGIQLQEEQTALRQIEKLGFKRQDVRHIILTHLDFDHAGGITDFPEAQVHV  121

Query  157  TAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLV  216
              +E   A H  +   R RYR  QW+     V +  DGE W GF S + L S+   ++LV
Sbjct  122  LGSELEAARHPHNFLARQRYRSQQWSSEKNWVTYALDGEKWFGFESVRDLKSLPPEILLV  181

Query  217  PMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLD-GRFRVPFVMRAEEKLLSYNRNQLR  275
            P+ GHTRGH  VAV A   W+LH GDA++ RG +D  ++     +R  ++++  +R    
Sbjct  182  PLAGHTRGHTGVAVRAEDGWLLHAGDAYFFRGEMDPEKYHCTLGLRLFQRIMEVDRKVRL  241

Query  276  DNQARIVELHRRHDPDLLIVCAHD  299
            +NQ R+ +L+R H  ++ I  AHD
Sbjct  242  ENQERLRQLNRDHHQEVQIFSAHD  265


>gi|335423974|ref|ZP_08552992.1| beta-lactamase [Salinisphaera shabanensis E1L3A]
 gi|334890725|gb|EGM28987.1| beta-lactamase [Salinisphaera shabanensis E1L3A]
Length=279

 Score =  216 bits (549),  Expect = 5e-54, Method: Compositional matrix adjust.
 Identities = 119/274 (44%), Positives = 162/274 (60%), Gaps = 16/274 (5%)

Query  49   PPVKVHHLNCGTMNAFGIALL-------------CHVLLVETDDGLVLVDTGFGIQDCLD  95
            P  K+HHLNC +M+     LL             CH LL+E++ GL+LVDTG G+ D  +
Sbjct  2    PAPKIHHLNCASMHPIAGPLLEHRSQLADYRGLVCHCLLIESEAGLILVDTGLGLADVTE  61

Query  96   P-GRVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAH  153
               R+G +F HV+RPA  + ETA  QIE LG+  +DVRHIVLTH D DH GGI DFP+AH
Sbjct  62   GRSRLGAMFSHVVRPAMRREETARHQIEALGFSANDVRHIVLTHLDVDHAGGIGDFPQAH  121

Query  154  LHVTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGV  213
            +HV A+E   A     ++ER RYR  QWAH      +   GE W GF + + +    + +
Sbjct  122  VHVLASEYAAARARRHIKERDRYRPAQWAHSDDWTRYEATGERWHGFDAVRAVVDSDSDI  181

Query  214  VLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQ  273
            +LVP+ GHTRGHAA+AV A   W+LH GDA++HR  +  R   P  ++  E L++ +   
Sbjct  182  LLVPITGHTRGHAAIAVRAPAGWLLHAGDAYFHRDEMADRPCCPLGLKVFENLMAVDNRD  241

Query  274  LRDNQARIVELHRRHDPDLLIVCAHDPDLYQLAR  307
             R NQAR+ EL      D+ + C+HDP  +  AR
Sbjct  242  RRRNQARLREL-ALGASDVSVFCSHDPVEFAHAR  274


>gi|300868753|ref|ZP_07113364.1| Beta-lactamase domain protein [Oscillatoria sp. PCC 6506]
 gi|300333314|emb|CBN58556.1| Beta-lactamase domain protein [Oscillatoria sp. PCC 6506]
Length=279

 Score =  205 bits (521),  Expect = 8e-51, Method: Compositional matrix adjust.
 Identities = 111/263 (43%), Positives = 150/263 (58%), Gaps = 14/263 (5%)

Query  51   VKVHHLNCGTMNAFGIALL------------CHVLLVETDDGLVLVDTGFGIQDCLDP-G  97
            +++HHLNCG M   G AL             CH LLVETD GLVL+DTGFG++D   P  
Sbjct  1    MQIHHLNCGCMCPIGGALFDGFSRSLNAHLVCHCLLVETDRGLVLIDTGFGLRDIQSPYS  60

Query  98   RVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHV  156
            R+   F H     F +  TA  QIEQLG+  SDVRHIVLTH DFDH GG+ DFPEA +H+
Sbjct  61   RLSPFFVHFNNIQFDRKYTAIHQIEQLGFAASDVRHIVLTHLDFDHAGGLEDFPEATVHI  120

Query  157  TAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLV  216
              AE   A     L  + RYR GQW        +   GEPW GF + + LD +   ++L+
Sbjct  121  MQAEMDAAQDRHGLIAKGRYRPGQWDEVKHWKYYSAKGEPWFGFEAVRDLDGLPPEILLI  180

Query  217  PMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRD  276
            P+ GHTRGHA VA++    W+LH GDA+++R  ++   R    +RA + ++  +R     
Sbjct  181  PLAGHTRGHAGVAIETQEGWLLHAGDAYFYRHEMNANRRCTPGLRAYQWMMEVDRQARLF  240

Query  277  NQARIVELHRRHDPDLLIVCAHD  299
            NQ R+  L  +   D+ + C+HD
Sbjct  241  NQDRLQALSVQRSKDVSLFCSHD  263


>gi|149926911|ref|ZP_01915170.1| hypothetical protein LMED105_12957 [Limnobacter sp. MED105]
 gi|149824463|gb|EDM83681.1| hypothetical protein LMED105_12957 [Limnobacter sp. MED105]
Length=271

 Score =  204 bits (520),  Expect = 1e-50, Method: Compositional matrix adjust.
 Identities = 115/270 (43%), Positives = 161/270 (60%), Gaps = 20/270 (7%)

Query  51   VKVHHLNCGTM--------NAFG-----IALLCHVLLVETDDGLVLVDTGFGIQDCLDPG  97
            +K+HH+NCGTM        N  G       ++CH LLVE++ GL+LVDTG G  D L+P 
Sbjct  1    MKIHHMNCGTMCPICKRLINGSGGFFERANMVCHCLLVESEQGLILVDTGLGTGDVLEPN  60

Query  98   R-VGL-FRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLH  155
            R +G  F  +L P     ETA  Q++ LG++ SDV+HIV TH D DH GG++DFP A +H
Sbjct  61   RRLGAGFVAMLAPQLRMEETAIEQVKNLGFKVSDVKHIVPTHLDLDHAGGLSDFPGAQVH  120

Query  156  VTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVL  215
            V   E R AI  PSLR+ LR+R+ Q+ H PK   H    E W GF + +P+   G  +++
Sbjct  121  VFEPEHRHAI-KPSLRDSLRFRKAQFEHQPKWTIHDKPTETWFGFQAIRPI--AGIELLM  177

Query  216  VPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFR--VPFVMRAEEKLLSYNRNQ  273
            VP+ GHTRGH  VAV  G++W+LHCGDA++HR  +  +    +P  +   EKL+     +
Sbjct  178  VPLIGHTRGHVGVAVKNGNKWILHCGDAYFHRSEVALKHEDPMPAGVAFFEKLVQTLPAE  237

Query  274  LRDNQARIVELHRRHDPDLLIVCAHDPDLY  303
                QAR+ EL +    ++ + CAHDP  Y
Sbjct  238  RVATQARLRELVKSSGDEVELFCAHDPVEY  267


>gi|334118604|ref|ZP_08492693.1| beta-lactamase domain protein [Microcoleus vaginatus FGP-2]
 gi|333459611|gb|EGK88224.1| beta-lactamase domain protein [Microcoleus vaginatus FGP-2]
Length=278

 Score =  201 bits (511),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 111/264 (43%), Positives = 151/264 (58%), Gaps = 15/264 (5%)

Query  51   VKVHHLNCGTMNAFGIALL------------CHVLLVETDDGLVLVDTGFGIQDCLDP-G  97
            +++HHLNCG M   G AL             CH LLVET+ GLVL+DTGFG++D   P  
Sbjct  1    MQIHHLNCGCMCPIGGALFDGFSRGLTAHLVCHCLLVETNQGLVLIDTGFGLRDIQSPYS  60

Query  98   RVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHV  156
            R+   F H     F +  TA  QIEQLG+  SDVRHIVLTH DFDH GG+ DFPEA +HV
Sbjct  61   RLSPFFVHFNNIQFDRKYTAIHQIEQLGFSPSDVRHIVLTHLDFDHAGGLEDFPEATVHV  120

Query  157  TAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLV  216
              AE   A        + RYR GQW    +   +   GEPW GF + + LD +   ++L+
Sbjct  121  MQAEIDAAEDRHGFITKRRYRPGQWDEVKRWKYYSAGGEPWFGFEAVRDLDGLPPEILLI  180

Query  217  PMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLD-GRFRVPFVMRAEEKLLSYNRNQLR  275
            P+ GHTRGHA +A++    W+LH GDA+++R  +D    R    +RA + ++  +R    
Sbjct  181  PLVGHTRGHAGIAINTPDGWLLHAGDAYFYRHEMDAANRRCTPGLRAYQWMMEVDRKARL  240

Query  276  DNQARIVELHRRHDPDLLIVCAHD  299
             NQ R+  L  +H  D+ + C+HD
Sbjct  241  LNQGRLHALSVQHSKDVRLFCSHD  264


>gi|333919023|ref|YP_004492604.1| beta-lactamase class B [Amycolicicoccus subflavus DQS3-9A1]
 gi|333481244|gb|AEF39804.1| Beta-lactamase class B [Amycolicicoccus subflavus DQS3-9A1]
Length=266

 Score =  200 bits (508),  Expect = 3e-49, Method: Compositional matrix adjust.
 Identities = 113/269 (43%), Positives = 157/269 (59%), Gaps = 13/269 (4%)

Query  51   VKVHHLNCGTMNAFGI--ALLCHVLLVETD-DGLVLVDTGFGIQDCLDPGRVGLF--RHV  105
            ++VHHLNCGT    G+    + H LL+ET+  GLVLVD+G G  D  +P     F   + 
Sbjct  1    MRVHHLNCGTFAPLGMRKKFVTHCLLIETETSGLVLVDSGLGRADVTEPKTTMRFPISYT  60

Query  106  LRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAI  165
            LRP     ETA  Q+E+LGY   DVRHI+LTH DFDH GG+ DFPEA++H++AAE R A 
Sbjct  61   LRPQLAIDETAVSQVEKLGYSAKDVRHILLTHLDFDHAGGLRDFPEANVHISAAELRAAR  120

Query  166  HAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGH  225
            +  S+ ER RY R  + H P+ VEH   G  W GF + + +  +   ++ VP+ GHTRGH
Sbjct  121  NPSSVIERRRYSRATFDHKPRWVEHSEFGTRWFGFDAVRDIPGLPEQILYVPLEGHTRGH  180

Query  226  AAVAVDAG----HRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQARI  281
              VA++       RW+LH GD++Y    +      P V  A E +L  +++   +N AR+
Sbjct  181  CGVAINTAPQGPARWLLHAGDSYYSHTEIGTPPSHPRVFAAMESVLQTSKSARLNNLARL  240

Query  282  VELHRRHDPDLLIVCAHDPDLYQLARDTA  310
             E+ R    D  ++CAHDP    LAR +A
Sbjct  241  REVARYDAVD--VICAHDPA--DLARYSA  265


>gi|29827758|ref|NP_822392.1| metallo-beta-lactamase [Streptomyces avermitilis MA-4680]
 gi|29604859|dbj|BAC68927.1| putative metallo-beta-lactamase [Streptomyces avermitilis MA-4680]
Length=290

 Score =  200 bits (508),  Expect = 3e-49, Method: Compositional matrix adjust.
 Identities = 120/269 (45%), Positives = 162/269 (61%), Gaps = 14/269 (5%)

Query  51   VKVHHLNCGTM-----NAFGIALLCHVLLVETD-DGLVLVDTGFGIQDCLDPGRV--GLF  102
            V++HHLNCG+M     +A  +  +CH LLVETD DGLVLV++G G  D   P +     F
Sbjct  15   VRIHHLNCGSMRTIDTDAGSLPAVCHCLLVETDRDGLVLVESGIGTADVARPEQNLGADF  74

Query  103  RHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEAR  162
                +P    AETA  Q+  LG+R   VRHIVL+H D DH GG++DFP A +H+T AE R
Sbjct  75   LGRAQPVLDLAETALHQVTGLGFRPEGVRHIVLSHLDLDHAGGLSDFPWAKVHLTEAEHR  134

Query  163  GAIHAPSL--RERLRYRRGQWAHGPKLVEH-GPDGEPWRGFASAKPLDSIGTGVVLVPMP  219
             A+ AP     +R+RYR  QWAH P  V +    G+PW GF + +PLD +   ++LVP+ 
Sbjct  135  AAMAAPGAHPEDRVRYRPAQWAHRPHWVTYPEAQGDPWFGFDAVRPLDGLDAEILLVPLG  194

Query  220  GHTRGHAAVAVDAGHRWVLHCGDAFY-HRGTLDGRFRVPFVMRAEEKLLSYNRNQLRDNQ  278
            GHTRGH+A+AV    RW+LHCGDA+Y HR       R    M   +++   +R     N 
Sbjct  195  GHTRGHSAIAVRDTGRWLLHCGDAYYFHREIDPDDPRGHPGMDILQQITEVDRPLRLGNH  254

Query  279  ARIVELHRRHDPDLLIVCAHDPDLYQLAR  307
            AR+ EL RRH  ++ +  AHDP  ++LAR
Sbjct  255  ARLRELVRRHGDEVEVFSAHDP--WELAR  281


>gi|302530500|ref|ZP_07282842.1| metallo-beta-lactamase [Streptomyces sp. AA4]
 gi|302439395|gb|EFL11211.1| metallo-beta-lactamase [Streptomyces sp. AA4]
Length=282

 Score =  199 bits (507),  Expect = 4e-49, Method: Compositional matrix adjust.
 Identities = 119/277 (43%), Positives = 155/277 (56%), Gaps = 17/277 (6%)

Query  51   VKVHHLNCGTMNAFG-------------IALLCHVLLVETDDGLVLVDTGFGIQDCLDPG  97
            +KVHHLNCGTM   G               ++ H LLVET D LVLVDTGFG +   +  
Sbjct  1    MKVHHLNCGTMRPLGGKALDGRPGMLRRSTIVAHCLLVETADSLVLVDTGFGTRGVTESR  60

Query  98   RV--GLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLH  155
            R   G F  ++       ETA  QI  LG+  +DVRHIV+TH D DH GG+ADFP+A +H
Sbjct  61   RWLGGPFMAMVGAKPTMEETAVAQIRALGHDPADVRHIVMTHLDVDHAGGLADFPDATVH  120

Query  156  VTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVL  215
            V A E R A H  S  E+ RYR  Q+AH P    +   GE W GF + +PL  +   ++L
Sbjct  121  VRATERRAADHPKSFPEKTRYRAEQFAHSPLWSTYDEAGEKWFGFDAVRPLRGLPPEILL  180

Query  216  VPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRF-RVPFVMRAEEKLLSYNRNQL  274
            VP+PGHT GH+ VAVD G  W+LH GDA++  G +       P  MRA E +   + +  
Sbjct  181  VPLPGHTHGHSGVAVDTGDGWLLHAGDAYFFHGEVAPVHPHCPPGMRAFEVMNQMDGSAR  240

Query  275  RDNQARIVELHRRHDPDLLIVCAHDPDLYQ-LARDTA  310
            R N AR+  L R H  ++ +  AH P  +Q L R+TA
Sbjct  241  RANLARLQTLAREHQDEVSVFSAHSPVEFQALRRNTA  277


>gi|27378189|ref|NP_769718.1| hypothetical protein blr3078 [Bradyrhizobium japonicum USDA 110]
 gi|27351336|dbj|BAC48343.1| blr3078 [Bradyrhizobium japonicum USDA 110]
Length=292

 Score =  197 bits (500),  Expect = 3e-48, Method: Compositional matrix adjust.
 Identities = 111/273 (41%), Positives = 150/273 (55%), Gaps = 18/273 (6%)

Query  51   VKVHHLNCGTMNAFG-------------IALLCHVLLVETDDGLVLVDTGFGIQDCLDPG  97
            +K+HHLN GTM   G               ++CH LLVET DGL LVDTG G+ D   P 
Sbjct  18   MKIHHLNTGTMCPMGRRLVNGTGGLFQRARMVCHCLLVETGDGLALVDTGIGLGDIAAPD  77

Query  98   RVGLFRHVLR---PAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHL  154
            R+G  R  LR   P    +ETA  Q++ LGY  +DVRH++LTH D DH GG+ DFP A +
Sbjct  78   RLG--RRWLRQTAPRLDPSETALEQVKALGYSPADVRHVLLTHLDRDHAGGVPDFPHAAI  135

Query  155  HVTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVV  214
            HV  AE   A+ +       RY  GQW+HGP    +G  GE W GF   + L      ++
Sbjct  136  HVHRAEYDMAVQSRPAPPEGRYVTGQWSHGPSWTFYGEAGEDWFGFKGVRALGDKEADIL  195

Query  215  LVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQL  274
            ++P+ GHT GH  +AV +G  W+LH GD+++H G L    R+P V+   ++    +R Q 
Sbjct  196  MIPLAGHTLGHCGIAVRSGDTWLLHAGDSYFHHGQLAASPRMPLVLGYFQRRADMDRTQR  255

Query  275  RDNQARIVELHRRHDPDLLIVCAHDPDLYQLAR  307
              NQAR+  L   H   + IV +HDP  Y+  R
Sbjct  256  IANQARLRALKLAHGDRVRIVNSHDPVDYENCR  288


>gi|300790245|ref|YP_003770536.1| beta-lactamase class B [Amycolatopsis mediterranei U32]
 gi|299799759|gb|ADJ50134.1| beta-lactamase class B [Amycolatopsis mediterranei U32]
 gi|340531926|gb|AEK47131.1| beta-lactamase class B [Amycolatopsis mediterranei S699]
Length=274

 Score =  195 bits (496),  Expect = 6e-48, Method: Compositional matrix adjust.
 Identities = 116/266 (44%), Positives = 146/266 (55%), Gaps = 16/266 (6%)

Query  51   VKVHHLNCGTMNAFGIALL-------------CHVLLVETDDGLVLVDTGFGIQDCLDPG  97
            +KVHHLNCG+M   G  LL              H LL+ET D LVLVDTGFG Q    PG
Sbjct  1    MKVHHLNCGSMRPVGGKLLDGEPGLLRRSELVAHCLLIETGDSLVLVDTGFGSQGVARPG  60

Query  98   RV--GLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLH  155
                G F  ++      AETA  QIE LG   +DVRHIV TH D DH GG+ADFP A +H
Sbjct  61   EWLGGPFLALVGAKPAAAETAVAQIEALGLDPADVRHIVATHLDVDHAGGLADFPNAVVH  120

Query  156  VTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVL  215
            V A E R A    +  E+ RYR  Q+AH P    +   GEPW GF + + L  +   ++L
Sbjct  121  VRAEEHRAATSPANAAEKNRYRAAQFAHRPLWSTYDEPGEPWFGFEAVRSLKGLPEEILL  180

Query  216  VPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRF-RVPFVMRAEEKLLSYNRNQL  274
            VP+ GHTRGH  VAVD G  W+LH GDA++  G LD      P  + A + ++   R   
Sbjct  181  VPLTGHTRGHTGVAVDTGDGWLLHAGDAYFFHGQLDPVAPHCPPGLTAFQNIVQTLRKPR  240

Query  275  RDNQARIVELHRRHDPDLLIVCAHDP  300
             +N AR+ EL R H  ++ +  AH P
Sbjct  241  LENLARLHELARTHQDEVTVFSAHSP  266


>gi|338531343|ref|YP_004664677.1| metallo-beta-lactamase family protein [Myxococcus fulvus HW-1]
 gi|337257439|gb|AEI63599.1| metallo-beta-lactamase family protein [Myxococcus fulvus HW-1]
Length=299

 Score =  194 bits (493),  Expect = 1e-47, Method: Compositional matrix adjust.
 Identities = 115/268 (43%), Positives = 154/268 (58%), Gaps = 19/268 (7%)

Query  51   VKVHHLNCGTMNAFG-------------IALLCHVLLVETDDGLVLVDTGFGIQDCLD--  95
            +++HHLNC TM   G              AL CH LLVE   GLVLVDTGFG++D     
Sbjct  1    MRIHHLNCTTMCPPGGRLVDGRKGFTGPAALTCHCLLVEGPRGLVLVDTGFGLEDVKHRR  60

Query  96   PGRVGLFRHVL-RPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHL  154
            P    LF  VL RP   +  TA RQ+E+LG++  DVR IVLTH DFDH GG+ DFP A +
Sbjct  61   PRLAPLFLDVLTRPQLNEGSTAIRQLERLGFKAEDVRDIVLTHLDFDHAGGLDDFPHARV  120

Query  155  HVTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEH--GPDGEPWRGFASAKPLDSIGTG  212
            H+ + E + A+   +  +R RYR  QW H    V +  G DGE W GF   + L  +   
Sbjct  121  HLLSDEYQSAVAQATPLDRRRYRPLQWLHESHWVTYPSGGDGERWFGFECVRDLSGLPPE  180

Query  213  VVLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTL-DGRFRVPFVMRAEEKLLSYNR  271
            ++LVP+PGHT GHA VA+  G  W+LH GDA+++ G +   R+R    +RA +KL+  + 
Sbjct  181  ILLVPLPGHTLGHAGVAIQHGGGWLLHAGDAYFYHGEMAPDRYRCTPGLRAYQKLMQKDG  240

Query  272  NQLRDNQARIVELHRRHDPDLLIVCAHD  299
                 N  R+ EL +RH  D+ + CAHD
Sbjct  241  YLRWHNMRRLRELVQRHGRDVTVFCAHD  268


>gi|319948139|ref|ZP_08022302.1| beta-lactamase domain protein [Dietzia cinnamea P4]
 gi|319438207|gb|EFV93164.1| beta-lactamase domain protein [Dietzia cinnamea P4]
Length=268

 Score =  192 bits (488),  Expect = 6e-47, Method: Compositional matrix adjust.
 Identities = 118/267 (45%), Positives = 149/267 (56%), Gaps = 20/267 (7%)

Query  51   VKVHHLNCGTMNAFGIALLCHVLLVETDDGLVLVDTGFGIQDCLDP-GRVGLFRHVLRPA  109
            +++H +NCGT           VLL+E   GLVLVD+G G+ D  DP GR+G  RHVLRPA
Sbjct  1    MRIHQMNCGTFAGLAP---TRVLLLEAPGGLVLVDSGIGLADIADPAGRLGAARHVLRPA  57

Query  110  FLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPS  169
              + ETA R+IE LG    DVRHIVLTH D DHIGG+ADFP A +HV+A     A+  P 
Sbjct  58   LRERETAVRRIEALGLDPRDVRHIVLTHLDLDHIGGLADFPAAQVHVSAQALTWAVRTPR  117

Query  170  LRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVA  229
              ER RYRR QWAHGP+  E+    + W GF    PLD +  G++LV +PGH  GHA V 
Sbjct  118  FLERRRYRRRQWAHGPRFTEYSFGADRWEGF-RVHPLDHVAEGMLLVDLPGHAVGHAGVF  176

Query  230  VDA---------------GHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQL  274
            V                   + VLH GDAFY RG +    RVP  +   E++++     +
Sbjct  177  VPGRGGDPSAAGDGGVDDDDKDVLHAGDAFYQRGQVGSAGRVPAWVPVMERVMALEPAAV  236

Query  275  RDNQARIVELHRRHDPDLLIVCAHDPD  301
                AR+  L  R    L +VCAHDP 
Sbjct  237  EVTHARLAGLAARRADTLDVVCAHDPS  263


>gi|115372222|ref|ZP_01459532.1| metallo-beta-lactamase superfamily protein [Stigmatella aurantiaca 
DW4/3-1]
 gi|310817386|ref|YP_003949744.1| metallo-beta-lactamase family protein [Stigmatella aurantiaca 
DW4/3-1]
 gi|115370687|gb|EAU69612.1| metallo-beta-lactamase superfamily protein [Stigmatella aurantiaca 
DW4/3-1]
 gi|309390458|gb|ADO67917.1| Metallo-beta-lactamase family protein [Stigmatella aurantiaca 
DW4/3-1]
Length=304

 Score =  191 bits (486),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 113/267 (43%), Positives = 157/267 (59%), Gaps = 18/267 (6%)

Query  51   VKVHHLNCGTMNAFG-------------IALLCHVLLVETDDGLVLVDTGFGIQDCLDP-  96
            ++VHHLNC TM   G              AL+CH LLVETD  LVLVDTGFG+ D L P 
Sbjct  3    LRVHHLNCTTMCPPGGRLMDGRMDVSGPAALVCHCLLVETDRSLVLVDTGFGLNDVLRPR  62

Query  97   GRVG--LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHL  154
             R+     + + RP   +  TA RQIE+LG++ +DVR I+LTH DFDH GG+ DFP A +
Sbjct  63   PRLSPLFLKGLCRPQLQEEMTAIRQIERLGFQATDVRDILLTHLDFDHAGGLDDFPWARV  122

Query  155  HVTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGP-DGEPWRGFASAKPLDSIGTGV  213
            HV  AE  GA+   +  ++ R+R GQW +   +    P  GE W GF   + L  +   +
Sbjct  123  HVLDAEYLGAVAQKTALDQRRFRPGQWMNVNWVTYPMPHGGERWFGFECVRELAGLPPEL  182

Query  214  VLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDG-RFRVPFVMRAEEKLLSYNRN  272
            +++P+ GHT GH+ +A+    RW+LH GDA++H   +DG R R P  +R  + L+  NR 
Sbjct  183  LILPLQGHTLGHSGIALQVDGRWLLHAGDAYFHHREMDGDRRRCPPGLRLYQTLMEKNRR  242

Query  273  QLRDNQARIVELHRRHDPDLLIVCAHD  299
            Q  +NQ R+ EL R H  ++ + CAHD
Sbjct  243  QRLENQGRLRELVRNHGSEVTVFCAHD  269


>gi|209516791|ref|ZP_03265642.1| beta-lactamase domain protein [Burkholderia sp. H160]
 gi|209502754|gb|EEA02759.1| beta-lactamase domain protein [Burkholderia sp. H160]
Length=287

 Score =  191 bits (485),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 110/272 (41%), Positives = 155/272 (57%), Gaps = 18/272 (6%)

Query  51   VKVHHLNCGT----MNAFGIA----------LLCHVLLVETDDGLVLVDTGFGIQDCLDP  96
            +KVHHLNC +         I           L+CH LLVE+  GLVLVDTGFG++D  DP
Sbjct  1    MKVHHLNCASSCPLCGKLSIGHPDSLIRRGHLICHCLLVESPAGLVLVDTGFGLRDVADP  60

Query  97   -GRVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHL  154
              R+G  F  +L+P F    TA RQ+E+LG++ +DVRHIV+TH D DH GG+ DFP A +
Sbjct  61   HSRLGKFFLRMLKPEFRNEMTAIRQVERLGFKPTDVRHIVMTHLDADHAGGLDDFPHATV  120

Query  155  HVTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPD-GEPWRGFASAKPLDSIGTGV  213
            H+ A+E + A    +  +R R+R  QW++      H P   E W GFA   P++ + + +
Sbjct  121  HMLASERQYAAQQKTWLDRQRFRPQQWSYQNMWRVHSPQYSERWEGFAKVHPIEELASEI  180

Query  214  VLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLD-GRFRVPFVMRAEEKLLSYNRN  272
             LVP+ GHT GHA VAV     W+L  GDA++  G LD  R      +   + +L+ +R 
Sbjct  181  ALVPLRGHTYGHAGVAVRGDRGWMLLAGDAYFDSGELDPERPHCAPGLHFYQWMLAKDRA  240

Query  273  QLRDNQARIVELHRRHDPDLLIVCAHDPDLYQ  304
                NQ R+ +L +R  P L I C+HD D ++
Sbjct  241  ARLYNQRRLRDLAKRASPALAIFCSHDADEFE  272


>gi|295681169|ref|YP_003609743.1| metallo-beta-lactamase superfamily protein [Burkholderia sp. 
CCGE1002]
 gi|295441064|gb|ADG20232.1| metallo-beta-lactamase superfamily protein [Burkholderia sp. 
CCGE1002]
Length=288

 Score =  191 bits (485),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 116/272 (43%), Positives = 154/272 (57%), Gaps = 18/272 (6%)

Query  51   VKVHHLNC-GTMNAFGIA-------------LLCHVLLVETDDGLVLVDTGFGIQDCLDP  96
            +KVHHLNC  T    G+              L CH LLVE+  GLVLVDTGFG++D  DP
Sbjct  1    MKVHHLNCISTCPLCGMLFNGQPASLVRRGRLACHCLLVESPAGLVLVDTGFGLRDVADP  60

Query  97   -GRVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHL  154
              R+G  F  +L+P F    TA RQIE+LG   +DVRHIV+TH DFDH GG+ DFP A +
Sbjct  61   YSRLGKFFLRLLKPEFRNEMTAIRQIERLGLDPADVRHIVMTHLDFDHAGGLDDFPHATV  120

Query  155  HVTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPD-GEPWRGFASAKPLDSIGTGV  213
            H+ A+E + A    +  +R RYR  QW++      H P   E W GFA   P++ + + +
Sbjct  121  HMLASERQYAAQQKTWLDRQRYRPQQWSYQNMWRVHSPQYTERWEGFAKVHPIEELASEI  180

Query  214  VLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDG-RFRVPFVMRAEEKLLSYNRN  272
             LVP+ GHT GHA VAV     W+L  GDA++  G LD  R      +R  + LL  +R 
Sbjct  181  ALVPLRGHTYGHAGVAVHGDGGWLLLAGDAYFDTGELDPVRPHCAPGLRFYQWLLEKDRA  240

Query  273  QLRDNQARIVELHRRHDPDLLIVCAHDPDLYQ  304
                NQ R+ +L +R  P L I C+HD D ++
Sbjct  241  ARLYNQRRLRDLAKRASPGLRIFCSHDVDEFE  272


>gi|300790244|ref|YP_003770535.1| beta-lactamase class B [Amycolatopsis mediterranei U32]
 gi|299799758|gb|ADJ50133.1| beta-lactamase class B [Amycolatopsis mediterranei U32]
 gi|340531925|gb|AEK47130.1| beta-lactamase class B [Amycolatopsis mediterranei S699]
Length=277

 Score =  189 bits (480),  Expect = 5e-46, Method: Compositional matrix adjust.
 Identities = 108/265 (41%), Positives = 145/265 (55%), Gaps = 17/265 (6%)

Query  51   VKVHHLNCGTMNAFG-------------IALLCHVLLVETDDGLVLVDTGFGIQDCLDPG  97
            ++VHHLNCGT+   G               ++CH LL+ETD GLVLV+TG G    +D  
Sbjct  1    MRVHHLNCGTLRPLGGKLIDGRPGLFRRATMVCHCLLLETDTGLVLVETGMGTPAAVDRN  60

Query  98   R---VGLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHL  154
                 G  R    P    A+TA  QI  LG+  +DVR IVLTH D DH GG+ DFP A +
Sbjct  61   AWLGAGFVRQS-NPVEDPAQTAIAQIRALGFDPADVRDIVLTHLDLDHAGGLIDFPWARV  119

Query  155  HVTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVV  214
            HV A E R         ER RYRR Q+AHGP+   +   GEPW GF + + LD +   V+
Sbjct  120  HVYAEELRAFTEPRDAAERGRYRRIQFAHGPQWTSYTDSGEPWFGFDAVRQLDGLPPEVL  179

Query  215  LVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQL  274
            L+P+ GHTRGHA VAVD GH W+L+ GD+++  G +      P  ++  E  +   R   
Sbjct  180  LIPLSGHTRGHAGVAVDTGHGWLLNAGDSYFFHGQVAAAPHCPPGLKWFEGHMETVRGAR  239

Query  275  RDNQARIVELHRRHDPDLLIVCAHD  299
             DN  R+ +L + H  ++ +  AHD
Sbjct  240  LDNHRRLRQLGQEHGDEVTVFAAHD  264


>gi|134098838|ref|YP_001104499.1| metallo-beta-lactamase [Saccharopolyspora erythraea NRRL 2338]
 gi|291005804|ref|ZP_06563777.1| metallo-beta-lactamase [Saccharopolyspora erythraea NRRL 2338]
 gi|133911461|emb|CAM01574.1| metallo-beta-lactamase [Saccharopolyspora erythraea NRRL 2338]
Length=305

 Score =  189 bits (479),  Expect = 6e-46, Method: Compositional matrix adjust.
 Identities = 112/266 (43%), Positives = 153/266 (58%), Gaps = 19/266 (7%)

Query  51   VKVHHLNCGTMNAFGIALL-------------CHVLLVETDDGLVLVDTGFGIQDCL-DP  96
            ++VHHLNCGTM  +G  L+             CH LLVET+ GLVLVDTG G +D   D 
Sbjct  1    MRVHHLNCGTMRPWGGGLVNRAGGLLGAARMVCHCLLVETEQGLVLVDTGLGTRDVTTDR  60

Query  97   GRVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLH  155
             ++   +R + RP     ETAA Q+ +LG+R  DVRHIVLTH D DH GG+ DFP A +H
Sbjct  61   DKLERSWRWLARPVLDAGETAAAQVVRLGHRLEDVRHIVLTHLDRDHAGGLPDFPHAQVH  120

Query  156  VTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEH-GPDGEPWRGFASAKPLDSIGTGVV  214
            V  AE +     P   ER RY   QW HGP+   H G DGE W GF + + +  +   ++
Sbjct  121  VLDAEYQAMRDNP---ERDRYLGHQWQHGPRWNPHRGDDGERWFGFEAVRDIPGLPPEIL  177

Query  215  LVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQL  274
            LVP+PGHTRGH AVAV    +W++H GDA++  G +  +      +R  ++ +  +    
Sbjct  178  LVPLPGHTRGHTAVAVRTADKWLVHAGDAYFFHGEMAQQPWCTPGLRYFQRQMQVDGPAR  237

Query  275  RDNQARIVELHRRHDPDLLIVCAHDP  300
              N+AR+ EL   H  ++ + CAHDP
Sbjct  238  VRNRARLRELAIAHPDEVEVFCAHDP  263


>gi|186681285|ref|YP_001864481.1| beta-lactamase domain-containing protein [Nostoc punctiforme 
PCC 73102]
 gi|186463737|gb|ACC79538.1| beta-lactamase domain protein [Nostoc punctiforme PCC 73102]
Length=277

 Score =  187 bits (476),  Expect = 1e-45, Method: Compositional matrix adjust.
 Identities = 104/273 (39%), Positives = 147/273 (54%), Gaps = 15/273 (5%)

Query  51   VKVHHLNCGTMNAFGIALL------------CHVLLVETDDGLVLVDTGFGIQDCLDP-G  97
            ++++HLNCG M   G AL             CH LL+ET+ GLVL+DTGFG +D   P  
Sbjct  1    MRIYHLNCGCMCPIGGALFDGFSRGLTACLVCHCLLIETNQGLVLIDTGFGQRDMKAPLS  60

Query  98   RVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHV  156
            R+   F ++ R  F +  TA   IEQLG    DVRHIVLTH DFDH GG+ DFPEA +HV
Sbjct  61   RLSPFFMNLNRIKFEEKYTAVAAIEQLGLNPRDVRHIVLTHLDFDHAGGLEDFPEATVHV  120

Query  157  TAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLV  216
              +E   A          RYR GQW        +   GEPW GF + + L+ +   ++L+
Sbjct  121  MLSEIEAARERQGFVSSQRYRPGQWDEVKNWKYYSAGGEPWFGFEAVRNLEGLPPEILLI  180

Query  217  PMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFV-MRAEEKLLSYNRNQLR  275
            P+ GHT GHA VA++    W+LH GDA+++R  +    RV    +RA +  +  +R    
Sbjct  181  PLVGHTLGHAGVAIETSEGWLLHAGDAYFYRQEIGSPKRVCTPGLRAYQWFMEVDRKARL  240

Query  276  DNQARIVELHRRHDPDLLIVCAHDPDLYQLARD  308
             NQ ++  L   H  ++ + C+HD   ++   D
Sbjct  241  SNQDKLRALSLDHSSEVRLFCSHDAIEFKTFSD  273


>gi|255318709|ref|ZP_05359936.1| metallo-beta-lactamase family protein [Acinetobacter radioresistens 
SK82]
 gi|255304207|gb|EET83397.1| metallo-beta-lactamase family protein [Acinetobacter radioresistens 
SK82]
Length=286

 Score =  187 bits (474),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 105/271 (39%), Positives = 154/271 (57%), Gaps = 27/271 (9%)

Query  51   VKVHHLNC--------GTMNAFGIA-----LLCHVLLVETDDGLVLVDTGFGIQDCLDP-  96
            ++VH LN           M+ F  A     L C  +L+ET D LVLVDTGFG++D   P 
Sbjct  1    MRVHFLNSISTCPLGGALMDGFSYAKLRGRLTCTCVLIETADSLVLVDTGFGLRDIASPR  60

Query  97   GRVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLH  155
             R+G  FR ++ P + +  TA RQIE+LGY   DVRHI+L+H DFDH GG+ DFP A +H
Sbjct  61   TRLGWFFRFLVSPEWREEMTAIRQIERLGYDPRDVRHIILSHLDFDHAGGLDDFPHATVH  120

Query  156  VTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPD-GEPWRGFASAKPLDSIGTGVV  214
            +   E   A+   +  +R R+R  QW++  K   + PD GE W GF S + LD +   ++
Sbjct  121  MMQTERDYALSQKTWLDRQRFRPQQWSYREKWKVYNPDTGEGWYGFNSVRDLDGLPPEIL  180

Query  215  LVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFV------MRAEEKLLS  268
             VP+ GHT GHA +A+ AG +W+L+  DA+++   +D     P        +R  + +L 
Sbjct  181  FVPLSGHTHGHAGIAIQAGDKWLLNAADAYFYHKEID-----PVSPCCTPGLRFYQTMLE  235

Query  269  YNRNQLRDNQARIVELHRRHDPDLLIVCAHD  299
             +R     NQAR+ +LH+ H  ++ I C+HD
Sbjct  236  KDRKARLSNQARLRQLHQHHAHEIDIFCSHD  266


>gi|262378110|ref|ZP_06071267.1| metallo-beta-lactamase superfamily protein [Acinetobacter radioresistens 
SH164]
 gi|262299395|gb|EEY87307.1| metallo-beta-lactamase superfamily protein [Acinetobacter radioresistens 
SH164]
Length=287

 Score =  187 bits (474),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 105/271 (39%), Positives = 154/271 (57%), Gaps = 27/271 (9%)

Query  51   VKVHHLNC--------GTMNAFGIA-----LLCHVLLVETDDGLVLVDTGFGIQDCLDP-  96
            ++VH LN           M+ F  A     L C  +L+ET D LVLVDTGFG++D   P 
Sbjct  2    MRVHFLNSISTCPLGGALMDGFSYAKLRGRLTCTCVLIETADSLVLVDTGFGLRDIASPR  61

Query  97   GRVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLH  155
             R+G  FR ++ P + +  TA RQIE+LGY   DVRHI+L+H DFDH GG+ DFP A +H
Sbjct  62   TRLGWFFRFLVSPEWREEMTAIRQIERLGYDPRDVRHIILSHLDFDHAGGLDDFPHATVH  121

Query  156  VTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPD-GEPWRGFASAKPLDSIGTGVV  214
            +   E   A+   +  +R R+R  QW++  K   + PD GE W GF S + LD +   ++
Sbjct  122  MMQTERDYALSQKTWLDRQRFRPQQWSYREKWKVYNPDTGEGWYGFNSVRDLDGLPPEIL  181

Query  215  LVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFV------MRAEEKLLS  268
             VP+ GHT GHA +A+ AG +W+L+  DA+++   +D     P        +R  + +L 
Sbjct  182  FVPLSGHTHGHAGIAIQAGDKWLLNAADAYFYHKEID-----PVSPCCTPGLRFYQTMLE  236

Query  269  YNRNQLRDNQARIVELHRRHDPDLLIVCAHD  299
             +R     NQAR+ +LH+ H  ++ I C+HD
Sbjct  237  KDRKARLSNQARLRQLHQHHAHEIDIFCSHD  267


>gi|332185382|ref|ZP_08387130.1| metallo-beta-lactamase superfamily protein [Sphingomonas sp. 
S17]
 gi|332014360|gb|EGI56417.1| metallo-beta-lactamase superfamily protein [Sphingomonas sp. 
S17]
Length=284

 Score =  187 bits (474),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 118/280 (43%), Positives = 157/280 (57%), Gaps = 24/280 (8%)

Query  51   VKVHHLNCGTMNAFGIAL------------LCHVLLVETDD-GLVLVDTGFGIQDCLDPG  97
            +++HHLNCGT    G AL            +CH LL+ETDD GLVLVDTG+G++D   P 
Sbjct  1    MRIHHLNCGTDCPLGGALFDGCSHGLLGHLVCHCLLIETDDHGLVLVDTGYGLKDVAHPH  60

Query  98   R------VGLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPE  151
            R         +R +L     + ETA RQIE LG+   DVRHIVLTH DFDH GG+ DFP 
Sbjct  61   RRPDPRITLAWRAMLNIRLREQETAIRQIEALGHDPRDVRHIVLTHLDFDHAGGLEDFPN  120

Query  152  AHLHVTAAEARGAIHAP--SLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSI  209
            A +HV   E   A  AP   +  R R+R  QW    +   H   GEPW GF + + L  +
Sbjct  121  ATVHVMQREYDDAA-APHAGIIARHRWRSRQWDGVTRWQRHSASGEPWFGFDAVRDLPGL  179

Query  210  GTGVVLVPMPGHTRGHAAVAV-DAGHRWVLHCGDAFYHRGTL-DGRFRVPFVMRAEEKLL  267
               ++LVP+PGHT GHA VAV   G RW+LH GDA+++RG + + R R    +RA ++L+
Sbjct  180  PPEILLVPLPGHTWGHAGVAVRQDGGRWLLHAGDAYFYRGEMREARRRCTPGLRAYQRLM  239

Query  268  SYNRNQLRDNQARIVELHRRHDPDLLIVCAHDPDLYQLAR  307
              +      NQAR+  L       + + CAHDP  ++  R
Sbjct  240  EVDAASRIANQARLRALSIDRRDAVTLTCAHDPLEWERCR  279


>gi|294624701|ref|ZP_06703369.1| metallo-beta-lactamase superfamily protein [Xanthomonas fuscans 
subsp. aurantifolii str. ICPB 11122]
 gi|292601009|gb|EFF45078.1| metallo-beta-lactamase superfamily protein [Xanthomonas fuscans 
subsp. aurantifolii str. ICPB 11122]
Length=321

 Score =  184 bits (467),  Expect = 1e-44, Method: Compositional matrix adjust.
 Identities = 108/291 (38%), Positives = 158/291 (55%), Gaps = 22/291 (7%)

Query  34   RLTTSMLGVAPEAKGPPVKVHHLNCGTMNAFGIALL--------------CHVLLVETDD  79
            R  T+ L   P  +  P++VHHLNC +    G  L+              CH LLVET  
Sbjct  12   RCATAALQCWPAKRSAPMRVHHLNCISTCPLGGHLMDGRTPGVLDRGHLCCHCLLVETSA  71

Query  80   GLVLVDTGFGIQDCLDP-GRVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTH  137
            GLVL+DTGFG++D  +P  R+   F  +++P   +  TA RQI++LG    DVRHIVLTH
Sbjct  72   GLVLIDTGFGLRDVAEPRARLSRFFLALVKPDLREDMTAIRQIQRLGLDPRDVRHIVLTH  131

Query  138  FDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQWA-HGPKLVEHGPDGEP  196
             DFDH GG+ DFP A +H+  +E   A+   +  +R R+R  QW+  G      G  GE 
Sbjct  132  LDFDHAGGLDDFPHARVHLMTSERDAALAQRTWMDRQRFRPQQWSTRGQWRTYDGAAGEH  191

Query  197  WRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRV  256
            W G    + L  +   +++VP+PGHT GHAAVAV    RW+L  GDA++    +D     
Sbjct  192  WMGLECVRDLHGLPLELLMVPLPGHTLGHAAVAVHTPERWLLLAGDAYFFHREMDA--DA  249

Query  257  PFV---MRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDPDLYQ  304
            P+    +RA + +L  +R     NQ R+  L ++H  ++ + C+HD   ++
Sbjct  250  PYCTPGLRAYQWMLEKDRTARLTNQQRLRALRQQHGGEVEVFCSHDVSEFE  300


>gi|294665924|ref|ZP_06731190.1| metallo-beta-lactamase superfamily protein [Xanthomonas fuscans 
subsp. aurantifolii str. ICPB 10535]
 gi|292604328|gb|EFF47713.1| metallo-beta-lactamase superfamily protein [Xanthomonas fuscans 
subsp. aurantifolii str. ICPB 10535]
Length=321

 Score =  184 bits (466),  Expect = 2e-44, Method: Compositional matrix adjust.
 Identities = 108/291 (38%), Positives = 158/291 (55%), Gaps = 22/291 (7%)

Query  34   RLTTSMLGVAPEAKGPPVKVHHLNCGTMNAFGIALL--------------CHVLLVETDD  79
            R  T+ L   P  +  P++VHHLNC +    G  L+              CH LLVET  
Sbjct  12   RCATAALQCWPAKRSAPMRVHHLNCISTCPLGGHLMDGRTPGVLDRGHLCCHCLLVETSA  71

Query  80   GLVLVDTGFGIQDCLDP-GRVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTH  137
            GLVL+DTGFG++D  +P  R+   F  +++P   +  TA RQI++LG    DVRHIVLTH
Sbjct  72   GLVLIDTGFGLRDVAEPRARLSRFFLALVKPDLREDMTAIRQIQRLGLDPRDVRHIVLTH  131

Query  138  FDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQWA-HGPKLVEHGPDGEP  196
             DFDH GG+ DFP A +H+  +E   A+   +  +R R+R  QW+  G      G  GE 
Sbjct  132  LDFDHAGGLDDFPHARVHLMTSERDAALAQRTWMDRQRFRPQQWSTRGQWRTYDGAAGEH  191

Query  197  WRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRV  256
            W G    + L  +   +++VP+PGHT GHAAVAV    RW+L  GDA++    +D     
Sbjct  192  WMGLECVRDLHGLPPELLMVPLPGHTLGHAAVAVHTPERWLLLAGDAYFFHREMDA--DA  249

Query  257  PFV---MRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDPDLYQ  304
            P+    +RA + +L  +R     NQ R+  L ++H  ++ + C+HD   ++
Sbjct  250  PYCTPGLRAYQWMLEKDRTARLTNQQRLRALRQQHGGEVEVFCSHDVSEFE  300


>gi|108758299|ref|YP_628344.1| metallo-beta-lactamase family protein [Myxococcus xanthus DK 
1622]
 gi|108462179|gb|ABF87364.1| metallo-beta-lactamase family protein [Myxococcus xanthus DK 
1622]
Length=298

 Score =  184 bits (466),  Expect = 2e-44, Method: Compositional matrix adjust.
 Identities = 108/267 (41%), Positives = 149/267 (56%), Gaps = 18/267 (6%)

Query  51   VKVHHLNCGTMNAFG-------------IALLCHVLLVETDDGLVLVDTGFGIQDCLDP-  96
            +++HHLNC TM   G              AL CH LLVE   GL+LVDTGFG++D   P 
Sbjct  1    MRIHHLNCTTMCPPGGRLVDGRKGFTGPAALTCHCLLVEGRQGLILVDTGFGLEDVKHPR  60

Query  97   GRV-GLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLH  155
             R+  L    +RP   +  TA RQIE++G+   DVR IVLTH D DH GG++DFP A +H
Sbjct  61   ARLHPLLLKGIRPRLNEGPTAIRQIERMGFHAEDVRDIVLTHLDCDHAGGLSDFPHAKIH  120

Query  156  VTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGP--DGEPWRGFASAKPLDSIGTGV  213
            +   E + A+   + R+R RYR  QW    + V +    DGE W GF   + L  +   +
Sbjct  121  LLWDEYQQALAQATARDRRRYRPQQWPPETQWVTYPSLGDGERWFGFECVRDLTGLPPEI  180

Query  214  VLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTL-DGRFRVPFVMRAEEKLLSYNRN  272
            +LVP+PGHT GHA VA+  G  W+LH GDA+++ G +   R++    +R  +KL   +  
Sbjct  181  LLVPLPGHTLGHAGVAIQNGSGWLLHAGDAYFYHGEMAPDRYQCTLGLRIAQKLNQTDGY  240

Query  273  QLRDNQARIVELHRRHDPDLLIVCAHD  299
                N  R+ EL  RH  D+ + CAHD
Sbjct  241  LRWHNMRRLRELVHRHGRDVTVFCAHD  267


>gi|260596820|ref|YP_003209391.1| hypothetical protein CTU_10280 [Cronobacter turicensis z3032]
 gi|260215997|emb|CBA28660.1| Uncharacterized protein Rv2300c/MT2357 [Cronobacter turicensis 
z3032]
Length=285

 Score =  183 bits (464),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 104/273 (39%), Positives = 149/273 (55%), Gaps = 15/273 (5%)

Query  47   KGPPVKVHHLNCGTMNAFGIAL------------LCHVLLVETDD-GLVLVDTGFGIQDC  93
            KG  ++VHHLNCG M   G AL            +CH LL+ET+  GLVLVDTGFG  D 
Sbjct  4    KGEAMRVHHLNCGCMCPLGGALYDGFSKGLHAHLICHCLLIETEHHGLVLVDTGFGCDDM  63

Query  94   LDPGR--VGLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPE  151
              PGR     FR +    + ++ TA   I+ LG++  DVRHIVLTH DFDH GGI+DFP 
Sbjct  64   RHPGRRLPLFFRALNNIQYRESLTALHHIQALGFKPEDVRHIVLTHLDFDHAGGISDFPH  123

Query  152  AHLHVTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGT  211
            A +H+   E   A    +  +  RYR GQW +      +   GEPW GF++ + LD +  
Sbjct  124  AQVHLMQREMTAADGRDTWLDTARYRPGQWGNRSGWHGYQAHGEPWFGFSAVRSLDGLPP  183

Query  212  GVVLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNR  271
             ++L+P+PGHT GHA VA+D    W+LH GDA+++R  +         +R  + ++  ++
Sbjct  184  EILLIPLPGHTEGHAGVAIDTPQGWLLHGGDAWFYRDEMAADPHCTPGLRFYQWMMQKDK  243

Query  272  NQLRDNQARIVELHRRHDPDLLIVCAHDPDLYQ  304
                 NQ R+  L       + + C+HD   ++
Sbjct  244  AARLANQKRLRLLAADASAGVRLFCSHDAREFE  276


>gi|221197486|ref|ZP_03570533.1| metallo-beta-lactamase superfamily protein [Burkholderia multivorans 
CGD2M]
 gi|221204159|ref|ZP_03577177.1| metallo-beta-lactamase superfamily protein [Burkholderia multivorans 
CGD2]
 gi|221176325|gb|EEE08754.1| metallo-beta-lactamase superfamily protein [Burkholderia multivorans 
CGD2]
 gi|221184040|gb|EEE16440.1| metallo-beta-lactamase superfamily protein [Burkholderia multivorans 
CGD2M]
Length=289

 Score =  182 bits (463),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 107/274 (40%), Positives = 155/274 (57%), Gaps = 17/274 (6%)

Query  53   VHHLNCGT--------MNA--FGI----ALLCHVLLVETDDGLVLVDTGFGIQDCLDP-G  97
            +HHLNC +        MN    GI    +L CH +L+ET D LVLVDTGFG++D  DP  
Sbjct  3    IHHLNCISTCPLCGRLMNGSRHGIFERGSLACHCVLIETRDSLVLVDTGFGLRDVADPRS  62

Query  98   RVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHV  156
            R+   F  ++ PAF +  TA RQIE+LGY   DVRHIVL+H DFDH GG+ DFPEA +H+
Sbjct  63   RLSRFFLGLVSPAFREEMTAIRQIERLGYDPRDVRHIVLSHLDFDHAGGLDDFPEATVHL  122

Query  157  TAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLV  216
               E   A    +  +R R+R  QW+   K   +   GE W+GFA  K L  +   ++LV
Sbjct  123  LETERAYAAAQRTWMDRQRFRPQQWSTSGKWRTYPDGGETWQGFAGVKALAGLPPSILLV  182

Query  217  PMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRD  276
            P+ GHT GHA +A++  H W+L+  DA++    ++   +    +R  + +L  +R     
Sbjct  183  PLRGHTLGHAGIAIETAHGWLLNAADAYFDAREMNANPQCHVGLRMYQWMLEKDRRARLA  242

Query  277  NQARIVELHRRHDPDLLIVCAHDPDLYQLARDTA  310
            NQA +  L +R +  +L+  +HDP  ++   D A
Sbjct  243  NQAALRALAQRRN-GVLVFSSHDPSEFERLADRA  275


>gi|221210586|ref|ZP_03583566.1| metallo-beta-lactamase superfamily protein [Burkholderia multivorans 
CGD1]
 gi|221169542|gb|EEE02009.1| metallo-beta-lactamase superfamily protein [Burkholderia multivorans 
CGD1]
Length=289

 Score =  182 bits (462),  Expect = 5e-44, Method: Compositional matrix adjust.
 Identities = 107/274 (40%), Positives = 155/274 (57%), Gaps = 17/274 (6%)

Query  53   VHHLNCGT--------MNA--FGI----ALLCHVLLVETDDGLVLVDTGFGIQDCLDP-G  97
            +HHLNC +        MN    GI    +L CH +L+ET D LVLVDTGFG++D  DP  
Sbjct  3    IHHLNCISTCPLCGRLMNGSRHGIFERGSLACHCVLIETRDSLVLVDTGFGLRDVADPRS  62

Query  98   RVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLHV  156
            R+   F  ++ PAF +  TA RQIE+LGY   DVRHIVL+H DFDH GG+ DFPEA +H+
Sbjct  63   RLSRFFLGLVSPAFREEMTAIRQIERLGYDPRDVRHIVLSHLDFDHAGGLDDFPEATVHL  122

Query  157  TAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVLV  216
               E   A    +  +R R+R  QW+   K   +   GE W+GFA  K L  +   ++LV
Sbjct  123  LETERAYAAAQRTWMDRQRFRPQQWSTSGKWRTYPDGGETWQGFAGVKALAGLPPSILLV  182

Query  217  PMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRVPFVMRAEEKLLSYNRNQLRD  276
            P+ GHT GHA +A++  H W+L+  DA++    ++   +    +R  + +L  +R     
Sbjct  183  PLRGHTLGHAGIAIETAHGWLLNAADAYFDAREMNANPQCHVGLRMYQWMLEKDRRARLA  242

Query  277  NQARIVELHRRHDPDLLIVCAHDPDLYQLARDTA  310
            NQA +  L +R +  +L+  +HDP  ++   D A
Sbjct  243  NQAALRALAQRRN-GVLVFSSHDPSEFERLADRA  275


>gi|308185502|ref|YP_003929634.1| hypothetical protein Pvag_pPag10124 [Pantoea vagans C9-1]
 gi|308055782|gb|ADO07952.1| hypothetical protein Pvag_pPag10124 [Pantoea vagans C9-1]
Length=279

 Score =  181 bits (459),  Expect = 1e-43, Method: Compositional matrix adjust.
 Identities = 106/265 (40%), Positives = 143/265 (54%), Gaps = 16/265 (6%)

Query  51   VKVHHLNCGTMNAFGIA------------LLCHVLLVETD-DGLVLVDTGFGIQDCLDPG  97
            +K+HHLNCG M   G A            L+CH LL+ETD DGLVLVDTGFG QD   PG
Sbjct  1    MKIHHLNCGCMCPLGGAFYDGFSKGLKAHLVCHCLLIETDRDGLVLVDTGFGRQDIHTPG  60

Query  98   R--VGLFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTHFDFDHIGGIADFPEAHLH  155
                G FR +         TA  Q++ LG++  DVRHI+LTH DFDH GG+ DFP+A +H
Sbjct  61   SRLSGFFRALNNIQRRDDLTALSQVKALGFQADDVRHIILTHLDFDHAGGLTDFPQARIH  120

Query  156  VTAAEARGAIHAPSLRERLRYRRGQWAHGPKLVEHGPDGEPWRGFASAKPLDSIGTGVVL  215
            +   E   A    S   R RYR GQW        + P GE W GF +   L  +   ++L
Sbjct  121  LLQQEVDTAHQRHSWLSRERYRPGQWGGIGNWETYQPQGETWFGFEAVNRLRDLPPEILL  180

Query  216  VPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFR-VPFVMRAEEKLLSYNRNQL  274
            VP+ GHT GHA +A+     W+LH GDA+++RG +    R     +R  + ++  +    
Sbjct  181  VPLAGHTPGHAGIAIQQPDGWLLHGGDAWFYRGEMRQPTRHCTPGLRFYQWMMGMDNEAR  240

Query  275  RDNQARIVELHRRHDPDLLIVCAHD  299
            R NQ R+ EL  +   ++   C+HD
Sbjct  241  RHNQQRLRELSCQRGGEITFFCSHD  265


>gi|78048122|ref|YP_364297.1| metallo-beta-lactamase superfamily protein [Xanthomonas campestris 
pv. vesicatoria str. 85-10]
 gi|78036552|emb|CAJ24243.1| metallo-beta-lactamase superfamily protein [Xanthomonas campestris 
pv. vesicatoria str. 85-10]
Length=321

 Score =  181 bits (458),  Expect = 2e-43, Method: Compositional matrix adjust.
 Identities = 108/291 (38%), Positives = 158/291 (55%), Gaps = 22/291 (7%)

Query  34   RLTTSMLGVAPEAKGPPVKVHHLNCGTMNAFGIALL--------------CHVLLVETDD  79
            R  T+ L   P  +  P++VHHLNC +    G  L+              CH LLVET  
Sbjct  12   RCATAALPRWPAKRSVPMRVHHLNCISTCPLGGHLMDGRTPGVLDRGHLCCHCLLVETSA  71

Query  80   GLVLVDTGFGIQDCLDP-GRVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTH  137
            GLVL+DTGFG++D  +P  R+   F  +++P   +  TA RQI++LG    DVRHIVLTH
Sbjct  72   GLVLIDTGFGLRDVAEPRARLSRFFLALVKPDLREEMTAIRQIQRLGLDPRDVRHIVLTH  131

Query  138  FDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQWA-HGPKLVEHGPDGEP  196
             DFDH GG+ DFP A +H+  +E   A+   +  +R R+R  QW+  G      G  GE 
Sbjct  132  LDFDHAGGLDDFPHARVHLMTSERDAALAQRTWMDRQRFRPQQWSTRGQWRTYDGAAGER  191

Query  197  WRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRV  256
            W G    + L  +   +++VP+PGHT GHAAVAV    RW+L  GDA++    +D     
Sbjct  192  WMGLECVRDLHGLPPELLMVPLPGHTLGHAAVAVHTPARWLLLAGDAYFFHREMDP--DA  249

Query  257  PFV---MRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDPDLYQ  304
            P+    +RA + +L  +R     NQ R+  L ++H  ++ + C+HD   ++
Sbjct  250  PYCTPGLRAYQWMLEKDRAARLSNQQRLRALRQQHAGEVEVFCSHDVSEFE  300


>gi|21108618|gb|AAM37220.1| conserved hypothetical protein [Xanthomonas axonopodis pv. citri 
str. 306]
Length=321

 Score =  181 bits (458),  Expect = 2e-43, Method: Compositional matrix adjust.
 Identities = 107/291 (37%), Positives = 157/291 (54%), Gaps = 22/291 (7%)

Query  34   RLTTSMLGVAPEAKGPPVKVHHLNCGTMNAFGIALL--------------CHVLLVETDD  79
            R  T+ L   P  +  P++VHHLNC +    G  L+              CH LLVET  
Sbjct  12   RCATAALQCWPAKRSAPMRVHHLNCISTCPLGGHLMDGRTPGVLERGHLCCHCLLVETSA  71

Query  80   GLVLVDTGFGIQDCLDP-GRVG-LFRHVLRPAFLQAETAARQIEQLGYRTSDVRHIVLTH  137
            GLVL+DTGFG++D  +P  R+   F  +++P   +  TA RQI++LG    DVRHIVLTH
Sbjct  72   GLVLIDTGFGLRDVAEPRARLSRFFLALVKPDLREDMTAIRQIQRLGLDPRDVRHIVLTH  131

Query  138  FDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQWA-HGPKLVEHGPDGEP  196
             DFDH GG+ DFP A +H+  +E   A+   +  +R R+R  QW+  G      G  GE 
Sbjct  132  LDFDHAGGLDDFPHARVHLMTSERDAALAQRTWMDRQRFRPQQWSTRGQWRTYDGAAGEH  191

Query  197  WRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAVDAGHRWVLHCGDAFYHRGTLDGRFRV  256
            W G    + L  +   +++VP+ GHT GHAAVAV    RW+L  GDA++    +D     
Sbjct  192  WMGLECVRDLHGLPPELLMVPLRGHTLGHAAVAVHTPERWLLLAGDAYFFHREMDA--DA  249

Query  257  PFV---MRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHDPDLYQ  304
            P+    +RA + +L  +R     NQ R+  L ++H  ++ + C+HD   ++
Sbjct  250  PYCTPGLRAYQWMLEKDRAARLTNQQRLRALRQQHGGEVEVFCSHDASEFE  300


>gi|337279707|ref|YP_004619179.1| hypothetical protein Rta_20670 [Ramlibacter tataouinensis TTB310]
 gi|334730784|gb|AEG93160.1| conserved hypothetical protein [Ramlibacter tataouinensis TTB310]
Length=285

 Score =  179 bits (455),  Expect = 3e-43, Method: Compositional matrix adjust.
 Identities = 107/245 (44%), Positives = 145/245 (60%), Gaps = 11/245 (4%)

Query  68   LLCHVLLVETDDGLVLVDTGFGIQDCLDP-GRV-GLFRHVLRPAFLQAETAARQIEQLGY  125
            L CH LL+ET+ GLVLVDTG G++D   P  R+ G F  +L P + +  TAARQ+ QLGY
Sbjct  14   LCCHCLLLETEQGLVLVDTGLGLRDVAHPRARLSGFFLALLSPEWREEMTAARQLAQLGY  73

Query  126  RTSDVRHIVLTHFDFDHIGGIADFPEAHLHVTAAEARGAIHAPSLRERLRYRRGQWAHGP  185
            +  DVRHIVLTH DFDH GG+ DFP+A +H+   E   A    +  +R R+R  QW    
Sbjct  74   QPRDVRHIVLTHLDFDHAGGLDDFPQATVHLLRQERDAAAAQATWLDRQRFRPQQWGTRA  133

Query  186  KLVEHG-PDGEPWRGFASAKPLDSIGTGVVLVPMPGHTRGHAAVAV--DAGHRWVLHCGD  242
                +G   GE W GF   +  + +   V+LVP+PGHT GHA VAV  D GH W+L  GD
Sbjct  134  NWRVYGAAGGERWFGFDGVRQPEGLPPEVLLVPLPGHTLGHAGVAVRRDDGH-WLLQAGD  192

Query  243  AFYHRGTLDGRFRVPFV---MRAEEKLLSYNRNQLRDNQARIVELHRRHDPDLLIVCAHD  299
            A++H   +D     P+    +R  + L+  +R    DNQAR+ EL R H  ++ +VC HD
Sbjct  193  AYFHHREMD--LERPWCTPGLRMYQALMEKDRRARLDNQARLRELRRAHGHEVELVCGHD  250

Query  300  PDLYQ  304
            P  ++
Sbjct  251  PVEFE  255



Lambda     K      H
   0.325    0.141    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 530605165806


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40