BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2306A

Length=197
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|57116962|ref|YP_177663.1|  hypothetical protein Rv2306A [Mycob...   383    6e-105
gi|31793484|ref|NP_855977.1|  hypothetical protein Mb2328 [Mycoba...   383    7e-105
gi|289443815|ref|ZP_06433559.1|  LOW QUALITY PROTEIN: possible co...   218    3e-55 
gi|183983522|ref|YP_001851813.1|  hypothetical protein MMAR_3541 ...   131    5e-29 
gi|118471337|ref|YP_887160.1|  hypothetical protein MSMEG_2840 [M...   122    3e-26 
gi|108802188|ref|YP_642385.1|  hypothetical protein Mmcs_5227 [My...   121    7e-26 
gi|342858881|ref|ZP_08715535.1|  hypothetical protein MCOL_08393 ...   119    2e-25 
gi|340625644|ref|YP_004744096.1|  hypothetical protein MCAN_06241...   116    2e-24 
gi|15840026|ref|NP_335063.1|  hypothetical protein MT0653 [Mycoba...   115    3e-24 
gi|15607765|ref|NP_215139.1|  transmembrane protein [Mycobacteriu...   115    4e-24 
gi|307083125|ref|ZP_07492238.1|  hypothetical protein TMLG_03375 ...   114    6e-24 
gi|41410188|ref|NP_963024.1|  hypothetical protein MAP4090c [Myco...   114    7e-24 
gi|240169395|ref|ZP_04748054.1|  hypothetical protein MkanA1_0878...   114    7e-24 
gi|298524114|ref|ZP_07011523.1|  conserved transmembrane protein ...   113    1e-23 
gi|336460590|gb|EGO39483.1|  hypothetical protein MAPs_39460 [Myc...   112    3e-23 
gi|118466458|ref|YP_883676.1|  hypothetical protein MAV_4545 [Myc...   112    3e-23 
gi|254776978|ref|ZP_05218494.1|  hypothetical protein MaviaA2_202...   111    7e-23 
gi|120402193|ref|YP_952022.1|  hypothetical protein Mvan_1181 [My...   110    8e-23 
gi|323720980|gb|EGB30045.1|  membrane protein [Mycobacterium tube...  99.4    2e-19 
gi|254823501|ref|ZP_05228502.1|  hypothetical protein MintA_26463...  87.0    1e-15 
gi|315446078|ref|YP_004078957.1|  hypothetical protein Mspyr1_457...  85.1    5e-15 
gi|145225727|ref|YP_001136405.1|  hypothetical protein Mflv_5151 ...  85.1    6e-15 
gi|296168387|ref|ZP_06850292.1|  conserved hypothetical protein [...  84.0    1e-14 
gi|284042519|ref|YP_003392859.1|  hypothetical protein Cwoe_1052 ...  51.6    7e-05 
gi|312882173|ref|ZP_07741921.1|  AcrB/AcrD/AcrF family protein [V...  48.9    4e-04 
gi|345125339|gb|EGW55209.1|  rhodanese domain protein [endosymbio...  48.1    6e-04 
gi|95931277|ref|ZP_01313995.1|  protein of unknown function DUF22...  46.2    0.003 
gi|300864069|ref|ZP_07108969.1|  conserved membrane hypothetical ...  42.4    0.042 
gi|117924412|ref|YP_865029.1|  rhodanese [Magnetococcus sp. MC-1]...  41.6    0.057 
gi|334119426|ref|ZP_08493512.1|  SNARE associated protein [Microc...  41.2    0.086 
gi|114319913|ref|YP_741596.1|  hypothetical protein Mlg_0752 [Alk...  40.8    0.11  
gi|17232678|ref|NP_489226.1|  hypothetical protein alr5186 [Nosto...  40.4    0.14  
gi|302036507|ref|YP_003796829.1|  hypothetical protein NIDE1145 [...  39.7    0.23  
gi|75908987|ref|YP_323283.1|  hypothetical protein Ava_2775 [Anab...  39.7    0.26  
gi|313896321|ref|ZP_07829874.1|  acriflavine resistance protein B...  38.1    0.65  
gi|148263625|ref|YP_001230331.1|  hypothetical protein Gura_1562 ...  38.1    0.74  
gi|186683627|ref|YP_001866823.1|  hypothetical protein Npun_R3472...  37.7    0.80  
gi|334127847|ref|ZP_08501749.1|  RND superfamily resistance-nodul...  37.7    0.93  
gi|90581492|ref|ZP_01237286.1|  AcrB/AcrD/AcrF family protein [Vi...  37.7    0.95  
gi|89073891|ref|ZP_01160398.1|  AcrB/AcrD/AcrF family protein [Ph...  37.7    0.95  
gi|116749667|ref|YP_846354.1|  hypothetical protein Sfum_2237 [Sy...  37.7    0.96  
gi|260886616|ref|ZP_05897879.1|  multidrug efflux RND transporter...  37.7    0.97  
gi|338849388|gb|AEJ27599.1|  RND efflux system inner membrane tra...  37.7    0.98  
gi|292670164|ref|ZP_06603590.1|  RND superfamily drug:proton (H+)...  37.4    1.3   
gi|238926903|ref|ZP_04658663.1|  possible acridine efflux pump [S...  37.4    1.3   
gi|304436757|ref|ZP_07396725.1|  RND superfamily drug:proton (H+)...  37.0    1.5   
gi|338811703|ref|ZP_08623908.1|  transporter, hydrophobe/amphiphi...  36.6    1.9   
gi|32476849|ref|NP_869843.1|  hypothetical protein RB11207 [Rhodo...  36.6    2.0   
gi|225025203|ref|ZP_03714395.1|  hypothetical protein EIKCOROL_02...  36.6    2.1   
gi|340029272|ref|ZP_08665335.1|  hydrophobe/amphiphile efflux-1 (...  36.6    2.2   


>gi|57116962|ref|YP_177663.1| hypothetical protein Rv2306A [Mycobacterium tuberculosis H37Rv]
 gi|167969841|ref|ZP_02552118.1| possible conserved membrane protein [Mycobacterium tuberculosis 
H37Ra]
 gi|253798628|ref|YP_003031629.1| hypothetical protein TBMG_04030 [Mycobacterium tuberculosis KZN 
1435]
 15 more sequence titles
 Length=197

 Score =  383 bits (984),  Expect = 6e-105, Method: Compositional matrix adjust.
 Identities = 197/197 (100%), Positives = 197/197 (100%), Gaps = 0/197 (0%)

Query  1    MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYV  60
            MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYV
Sbjct  1    MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYV  60

Query  61   VVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIASM  120
            VVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIASM
Sbjct  61   VVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIASM  120

Query  121  HRSNGADCGRWSVSASSPASRMRWPRTPSGRSEFRCGRWSLGRSSGRRHGCSSTPRWARR  180
            HRSNGADCGRWSVSASSPASRMRWPRTPSGRSEFRCGRWSLGRSSGRRHGCSSTPRWARR
Sbjct  121  HRSNGADCGRWSVSASSPASRMRWPRTPSGRSEFRCGRWSLGRSSGRRHGCSSTPRWARR  180

Query  181  SPTCRRRWFTRRSRCGA  197
            SPTCRRRWFTRRSRCGA
Sbjct  181  SPTCRRRWFTRRSRCGA  197


>gi|31793484|ref|NP_855977.1| hypothetical protein Mb2328 [Mycobacterium bovis AF2122/97]
 gi|121638187|ref|YP_978411.1| hypothetical protein BCG_2322 [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 gi|224990681|ref|YP_002645368.1| hypothetical protein JTY_2316 [Mycobacterium bovis BCG str. Tokyo 
172]
 12 more sequence titles
 Length=197

 Score =  383 bits (984),  Expect = 7e-105, Method: Compositional matrix adjust.
 Identities = 196/197 (99%), Positives = 197/197 (100%), Gaps = 0/197 (0%)

Query  1    MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYV  60
            MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSA+VVATGPIAPLAYV
Sbjct  1    MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAVVVATGPIAPLAYV  60

Query  61   VVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIASM  120
            VVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIASM
Sbjct  61   VVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIASM  120

Query  121  HRSNGADCGRWSVSASSPASRMRWPRTPSGRSEFRCGRWSLGRSSGRRHGCSSTPRWARR  180
            HRSNGADCGRWSVSASSPASRMRWPRTPSGRSEFRCGRWSLGRSSGRRHGCSSTPRWARR
Sbjct  121  HRSNGADCGRWSVSASSPASRMRWPRTPSGRSEFRCGRWSLGRSSGRRHGCSSTPRWARR  180

Query  181  SPTCRRRWFTRRSRCGA  197
            SPTCRRRWFTRRSRCGA
Sbjct  181  SPTCRRRWFTRRSRCGA  197


>gi|289443815|ref|ZP_06433559.1| LOW QUALITY PROTEIN: possible conserved membrane protein [Mycobacterium 
tuberculosis T46]
 gi|289416734|gb|EFD13974.1| LOW QUALITY PROTEIN: possible conserved membrane protein [Mycobacterium 
tuberculosis T46]
Length=113

 Score =  218 bits (556),  Expect = 3e-55, Method: Compositional matrix adjust.
 Identities = 112/113 (99%), Positives = 113/113 (100%), Gaps = 0/113 (0%)

Query  1    MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYV  60
            MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSA+VVATGPIAPLAYV
Sbjct  1    MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAVVVATGPIAPLAYV  60

Query  61   VVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVS  113
            VVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVS
Sbjct  61   VVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVS  113


>gi|183983522|ref|YP_001851813.1| hypothetical protein MMAR_3541 [Mycobacterium marinum M]
 gi|183176848|gb|ACC41958.1| conserved membrane protein [Mycobacterium marinum M]
Length=239

 Score =  131 bits (330),  Expect = 5e-29, Method: Compositional matrix adjust.
 Identities = 71/95 (75%), Positives = 81/95 (86%), Gaps = 1/95 (1%)

Query  2   TDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYVV  61
           TD   P+ SR RH++RLALFAG LLG+FYLVAVARVI + G+RSAI  ATGP+APLAYVV
Sbjct  6   TDPAPPSASRGRHLVRLALFAGFLLGMFYLVAVARVIDIAGIRSAIT-ATGPLAPLAYVV  64

Query  62  VSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           +S  LGA+FVPGPILAAGSGVLFGP+L TFVTL A
Sbjct  65  MSTVLGAVFVPGPILAAGSGVLFGPILGTFVTLGA  99


>gi|118471337|ref|YP_887160.1| hypothetical protein MSMEG_2840 [Mycobacterium smegmatis str. 
MC2 155]
 gi|118172624|gb|ABK73520.1| conserved hypothetical protein [Mycobacterium smegmatis str. 
MC2 155]
Length=232

 Score =  122 bits (305),  Expect = 3e-26, Method: Compositional matrix adjust.
 Identities = 68/97 (71%), Positives = 77/97 (80%), Gaps = 2/97 (2%)

Query  1   MTD-NECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAY  59
           MTD ++ PA  R RH++RLALFA  LLGLFYLVAVARV+ +  +R A V ATGPIAPL Y
Sbjct  1   MTDTDDPPATGRTRHIIRLALFAAFLLGLFYLVAVARVVEIGDIRGA-VSATGPIAPLVY  59

Query  60  VVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           VVVSA LGALFVPGP+LA  SG LFGP+L TFVTL A
Sbjct  60  VVVSACLGALFVPGPLLAGTSGFLFGPVLGTFVTLGA  96


>gi|108802188|ref|YP_642385.1| hypothetical protein Mmcs_5227 [Mycobacterium sp. MCS]
 gi|119871341|ref|YP_941293.1| hypothetical protein Mkms_5315 [Mycobacterium sp. KMS]
 gi|126438170|ref|YP_001073861.1| hypothetical protein Mjls_5607 [Mycobacterium sp. JLS]
 gi|108772607|gb|ABG11329.1| conserved hypothetical protein [Mycobacterium sp. MCS]
 gi|119697430|gb|ABL94503.1| conserved hypothetical protein [Mycobacterium sp. KMS]
 gi|126237970|gb|ABO01371.1| conserved hypothetical protein [Mycobacterium sp. JLS]
Length=220

 Score =  121 bits (303),  Expect = 7e-26, Method: Compositional matrix adjust.
 Identities = 65/87 (75%), Positives = 73/87 (84%), Gaps = 1/87 (1%)

Query  10  SRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYVVVSAALGAL  69
           SRRRH+ RLA+FA ++ GLFYLVAV RVI VD VR A V ATGP+APL YVVVSA LGAL
Sbjct  3   SRRRHIARLAVFAALVFGLFYLVAVERVIEVDAVRDA-VAATGPVAPLTYVVVSATLGAL  61

Query  70  FVPGPILAAGSGVLFGPLLDTFVTLPA  96
           FVPGP+LA GSG+LFGP+L TFVTL A
Sbjct  62  FVPGPLLAGGSGLLFGPVLGTFVTLGA  88


>gi|342858881|ref|ZP_08715535.1| hypothetical protein MCOL_08393 [Mycobacterium colombiense CECT 
3035]
 gi|342133122|gb|EGT86325.1| hypothetical protein MCOL_08393 [Mycobacterium colombiense CECT 
3035]
Length=240

 Score =  119 bits (299),  Expect = 2e-25, Method: Compositional matrix adjust.
 Identities = 67/97 (70%), Positives = 76/97 (79%), Gaps = 2/97 (2%)

Query  1   MTDNECP-ADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAY  59
           M DN  P   SRR H++RLA+FA  L  +FYLVAVARVI++D +R AIV ATGP APL Y
Sbjct  1   MDDNHAPPTASRRAHIVRLAVFAAFLGAVFYLVAVARVINIDEIR-AIVSATGPAAPLTY  59

Query  60  VVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           VVVSA +GALFVPG ILAAGSG+LFGPLL  FVTL A
Sbjct  60  VVVSAVVGALFVPGSILAAGSGLLFGPLLGVFVTLGA  96


>gi|340625644|ref|YP_004744096.1| hypothetical protein MCAN_06241 [Mycobacterium canettii CIPT 
140010059]
 gi|340003834|emb|CCC42964.1| putative conserved transmembrane protein [Mycobacterium canettii 
CIPT 140010059]
Length=246

 Score =  116 bits (290),  Expect = 2e-24, Method: Compositional matrix adjust.
 Identities = 65/95 (69%), Positives = 73/95 (77%), Gaps = 1/95 (1%)

Query  2   TDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYVV  61
           T N+    SRRRH++RL +FAG L+G+FYLVA   VI V  VR A V ATGP APLAYVV
Sbjct  3   THNDSAPTSRRRHIVRLVVFAGFLVGMFYLVAATDVIDVAAVRGA-VSATGPAAPLAYVV  61

Query  62  VSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           VSA LGALFVPGPILAA SG+LFGPL+  FVTL A
Sbjct  62  VSAVLGALFVPGPILAASSGLLFGPLVGVFVTLGA  96


>gi|15840026|ref|NP_335063.1| hypothetical protein MT0653 [Mycobacterium tuberculosis CDC1551]
 gi|254230959|ref|ZP_04924286.1| hypothetical protein TBCG_00619 [Mycobacterium tuberculosis C]
 gi|13880170|gb|AAK44877.1| hypothetical protein MT0653 [Mycobacterium tuberculosis CDC1551]
 gi|124600018|gb|EAY59028.1| hypothetical protein TBCG_00619 [Mycobacterium tuberculosis C]
Length=278

 Score =  115 bits (288),  Expect = 3e-24, Method: Compositional matrix adjust.
 Identities = 64/95 (68%), Positives = 72/95 (76%), Gaps = 1/95 (1%)

Query  2    TDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYVV  61
            T N+    SRRRH++RL +FAG L+G+FYLVA   VI V  VR A V ATGP APL YVV
Sbjct  35   THNDSAPTSRRRHIVRLVVFAGFLVGMFYLVAATDVIDVAAVRGA-VSATGPAAPLTYVV  93

Query  62   VSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
            VSA LGALFVPGPILAA SG+LFGPL+  FVTL A
Sbjct  94   VSAVLGALFVPGPILAASSGLLFGPLVGVFVTLGA  128


>gi|15607765|ref|NP_215139.1| transmembrane protein [Mycobacterium tuberculosis H37Rv]
 gi|31791807|ref|NP_854300.1| transmembrane protein [Mycobacterium bovis AF2122/97]
 gi|121636544|ref|YP_976767.1| putative transmembrane protein [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 67 more sequence titles
 Length=246

 Score =  115 bits (287),  Expect = 4e-24, Method: Compositional matrix adjust.
 Identities = 64/95 (68%), Positives = 72/95 (76%), Gaps = 1/95 (1%)

Query  2   TDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYVV  61
           T N+    SRRRH++RL +FAG L+G+FYLVA   VI V  VR A V ATGP APL YVV
Sbjct  3   THNDSAPTSRRRHIVRLVVFAGFLVGMFYLVAATDVIDVAAVRGA-VSATGPAAPLTYVV  61

Query  62  VSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           VSA LGALFVPGPILAA SG+LFGPL+  FVTL A
Sbjct  62  VSAVLGALFVPGPILAASSGLLFGPLVGVFVTLGA  96


>gi|307083125|ref|ZP_07492238.1| hypothetical protein TMLG_03375 [Mycobacterium tuberculosis SUMu012]
 gi|308367161|gb|EFP56012.1| hypothetical protein TMLG_03375 [Mycobacterium tuberculosis SUMu012]
Length=214

 Score =  114 bits (286),  Expect = 6e-24, Method: Compositional matrix adjust.
 Identities = 64/95 (68%), Positives = 72/95 (76%), Gaps = 1/95 (1%)

Query  2   TDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYVV  61
           T N+    SRRRH++RL +FAG L+G+FYLVA   VI V  VR A V ATGP APL YVV
Sbjct  3   THNDSAPTSRRRHIVRLVVFAGFLVGMFYLVAATDVIDVAAVRGA-VSATGPAAPLTYVV  61

Query  62  VSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           VSA LGALFVPGPILAA SG+LFGPL+  FVTL A
Sbjct  62  VSAVLGALFVPGPILAASSGLLFGPLVGVFVTLGA  96


>gi|41410188|ref|NP_963024.1| hypothetical protein MAP4090c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41399022|gb|AAS06640.1| hypothetical protein MAP_4090c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=233

 Score =  114 bits (285),  Expect = 7e-24, Method: Compositional matrix adjust.
 Identities = 67/98 (69%), Positives = 73/98 (75%), Gaps = 3/98 (3%)

Query  1   MTDNECPAD--SRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLA  58
           M D E P    SRR H+LRLA+FAG L  +FYLVAVARVI V  +R A+V ATGP APL 
Sbjct  1   MDDQEAPDAPASRRAHILRLAVFAGFLAVVFYLVAVARVIDVGAIR-AVVSATGPAAPLT  59

Query  59  YVVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           YVV SA  GALFVPG ILAAGSG+LFGPLL  FVTL A
Sbjct  60  YVVASALAGALFVPGSILAAGSGLLFGPLLGVFVTLGA  97


>gi|240169395|ref|ZP_04748054.1| hypothetical protein MkanA1_08783 [Mycobacterium kansasii ATCC 
12478]
Length=235

 Score =  114 bits (285),  Expect = 7e-24, Method: Compositional matrix adjust.
 Identities = 65/97 (68%), Positives = 75/97 (78%), Gaps = 2/97 (2%)

Query  1   MTDNE-CPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAY  59
           M DN   P  SRR H++RL +FAG LLGL+YLVAVARV+ V+ +R A V ATGP APL Y
Sbjct  1   MVDNPGSPLTSRRHHIVRLVVFAGFLLGLWYLVAVARVVDVEVMRRA-VSATGPAAPLTY  59

Query  60  VVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           VV SA LGALFVPGP+LAAGSG+LFGP+   FVTL A
Sbjct  60  VVASAVLGALFVPGPVLAAGSGLLFGPVEGIFVTLGA  96


>gi|298524114|ref|ZP_07011523.1| conserved transmembrane protein [Mycobacterium tuberculosis 94_M4241A]
 gi|298493908|gb|EFI29202.1| conserved transmembrane protein [Mycobacterium tuberculosis 94_M4241A]
Length=246

 Score =  113 bits (283),  Expect = 1e-23, Method: Compositional matrix adjust.
 Identities = 63/95 (67%), Positives = 71/95 (75%), Gaps = 1/95 (1%)

Query  2   TDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYVV  61
           T N+    SRRRH++RL +FAG L+G+FYLVA   VI V  VR A V ATGP  PL YVV
Sbjct  3   THNDSAPTSRRRHIVRLVVFAGFLVGMFYLVAATDVIDVAAVRGA-VSATGPAVPLTYVV  61

Query  62  VSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           VSA LGALFVPGPILAA SG+LFGPL+  FVTL A
Sbjct  62  VSAVLGALFVPGPILAASSGLLFGPLVGVFVTLGA  96


>gi|336460590|gb|EGO39483.1| hypothetical protein MAPs_39460 [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=233

 Score =  112 bits (281),  Expect = 3e-23, Method: Compositional matrix adjust.
 Identities = 66/98 (68%), Positives = 72/98 (74%), Gaps = 3/98 (3%)

Query  1   MTDNECPAD--SRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLA  58
           M D E P    SRR H+LRLA+FAG L  +FYLVAVARVI V  +R A+V ATGP APL 
Sbjct  1   MDDQEAPDAPASRRAHILRLAVFAGFLAVVFYLVAVARVIDVGAIR-AVVSATGPAAPLT  59

Query  59  YVVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           Y V SA  GALFVPG ILAAGSG+LFGPLL  FVTL A
Sbjct  60  YAVASALAGALFVPGSILAAGSGLLFGPLLGVFVTLGA  97


>gi|118466458|ref|YP_883676.1| hypothetical protein MAV_4545 [Mycobacterium avium 104]
 gi|118167745|gb|ABK68642.1| conserved hypothetical protein [Mycobacterium avium 104]
Length=233

 Score =  112 bits (280),  Expect = 3e-23, Method: Compositional matrix adjust.
 Identities = 66/98 (68%), Positives = 73/98 (75%), Gaps = 3/98 (3%)

Query  1   MTDNECPAD--SRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLA  58
           M + E P    SRR H+LRLA+FAG L  +FYLVAVARVI V  +R A+V ATGP APL 
Sbjct  1   MDNQEAPDAPASRRAHILRLAVFAGFLAVVFYLVAVARVIDVGEIR-AVVSATGPAAPLT  59

Query  59  YVVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           YVV SA  GALFVPG ILAAGSG+LFGPLL  FVTL A
Sbjct  60  YVVASALAGALFVPGSILAAGSGLLFGPLLGVFVTLGA  97


>gi|254776978|ref|ZP_05218494.1| hypothetical protein MaviaA2_20236 [Mycobacterium avium subsp. 
avium ATCC 25291]
Length=233

 Score =  111 bits (277),  Expect = 7e-23, Method: Compositional matrix adjust.
 Identities = 65/97 (68%), Positives = 74/97 (77%), Gaps = 4/97 (4%)

Query  3   DNECPAD---SRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAY  59
           D++  +D   SRR H+LRLA+FAG L  +FYLVAVARVI V  +R A+V ATGP APL Y
Sbjct  2   DDQDASDAPASRRAHILRLAVFAGFLAVVFYLVAVARVIDVGEIR-AVVSATGPAAPLTY  60

Query  60  VVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           VV SA  GALFVPG ILAAGSG+LFGPLL  FVTL A
Sbjct  61  VVASALAGALFVPGSILAAGSGLLFGPLLGVFVTLGA  97


>gi|120402193|ref|YP_952022.1| hypothetical protein Mvan_1181 [Mycobacterium vanbaalenii PYR-1]
 gi|119955011|gb|ABM12016.1| conserved hypothetical protein [Mycobacterium vanbaalenii PYR-1]
Length=229

 Score =  110 bits (276),  Expect = 8e-23, Method: Compositional matrix adjust.
 Identities = 62/97 (64%), Positives = 70/97 (73%), Gaps = 2/97 (2%)

Query  1   MTDNE-CPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAY  59
           M D E  P  SRRRH+ RLALF  +L  L+YL AV RVI V  VR  ++ +TGP APL Y
Sbjct  3   MEDTEGTPETSRRRHITRLALFGAVLAVLYYLTAVERVIDVAQVRG-LIESTGPAAPLTY  61

Query  60  VVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           V VSA LGAL VPGP+LAAGSG LFGPL+ TFVTL A
Sbjct  62  VAVSAVLGALLVPGPLLAAGSGFLFGPLVGTFVTLGA  98


>gi|323720980|gb|EGB30045.1| membrane protein [Mycobacterium tuberculosis CDC1551A]
 gi|339293662|gb|AEJ45773.1| hypothetical protein CCDC5079_0583 [Mycobacterium tuberculosis 
CCDC5079]
 gi|339297303|gb|AEJ49413.1| hypothetical protein CCDC5180_0576 [Mycobacterium tuberculosis 
CCDC5180]
Length=230

 Score = 99.4 bits (246),  Expect = 2e-19, Method: Compositional matrix adjust.
 Identities = 57/81 (71%), Positives = 63/81 (78%), Gaps = 1/81 (1%)

Query  16  LRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYVVVSAALGALFVPGPI  75
           +RL +FAG L+G+FYLVA   VI V  VR A V ATGP APL YVVVSA LGALFVPGPI
Sbjct  1   MRLVVFAGFLVGMFYLVAATDVIDVAAVRGA-VSATGPAAPLTYVVVSAVLGALFVPGPI  59

Query  76  LAAGSGVLFGPLLDTFVTLPA  96
           LAA SG+LFGPL+  FVTL A
Sbjct  60  LAASSGLLFGPLVGVFVTLGA  80


>gi|254823501|ref|ZP_05228502.1| hypothetical protein MintA_26463 [Mycobacterium intracellulare 
ATCC 13950]
Length=251

 Score = 87.0 bits (214),  Expect = 1e-15, Method: Compositional matrix adjust.
 Identities = 62/97 (64%), Positives = 69/97 (72%), Gaps = 4/97 (4%)

Query  3    DNECPAD---SRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAY  59
            D   PA    SRR  V+RLA+FA  L   FYLVAVA VI ++ +R  +V ATGP APL Y
Sbjct  9    DGPAPASQPVSRRGPVVRLAVFAAFLAVAFYLVAVAHVIDIEEIRR-VVSATGPAAPLTY  67

Query  60   VVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
            VVVSA  GALFVPG ILAAGSG+LFGPLL  FVTL A
Sbjct  68   VVVSAVAGALFVPGSILAAGSGLLFGPLLGVFVTLGA  104


>gi|315446078|ref|YP_004078957.1| hypothetical protein Mspyr1_45710 [Mycobacterium sp. Spyr1]
 gi|315264381|gb|ADU01123.1| uncharacterized conserved protein [Mycobacterium sp. Spyr1]
Length=227

 Score = 85.1 bits (209),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 58/97 (60%), Positives = 71/97 (74%), Gaps = 2/97 (2%)

Query  1   MTD-NECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAY  59
           MTD  + P  S+RR + RLAL   +L  LFYL A+ARVI V+ VR  ++ +TGP+APL Y
Sbjct  1   MTDPTDAPETSKRRALARLALVVAVLAVLFYLTAIARVIDVEAVRD-LIESTGPLAPLTY  59

Query  60  VVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           V VSA LGAL VPGP+LAAGSG LFGP++ T VTL A
Sbjct  60  VGVSAVLGALLVPGPLLAAGSGFLFGPVVGTVVTLGA  96


>gi|145225727|ref|YP_001136405.1| hypothetical protein Mflv_5151 [Mycobacterium gilvum PYR-GCK]
 gi|145218213|gb|ABP47617.1| conserved hypothetical protein [Mycobacterium gilvum PYR-GCK]
Length=227

 Score = 85.1 bits (209),  Expect = 6e-15, Method: Compositional matrix adjust.
 Identities = 58/97 (60%), Positives = 72/97 (75%), Gaps = 2/97 (2%)

Query  1   MTD-NECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAY  59
           MTD  + P  S+RR ++RLAL   +L  LFYL A+ARVI V+ VR  ++ +TGP+APL Y
Sbjct  1   MTDPTDAPETSKRRALVRLALVVAVLAVLFYLTAIARVIDVEAVRD-LIESTGPLAPLTY  59

Query  60  VVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
           V VSA LGAL VPGP+LAAGSG LFGP++ T VTL A
Sbjct  60  VGVSAVLGALLVPGPLLAAGSGFLFGPVVGTVVTLGA  96


>gi|296168387|ref|ZP_06850292.1| conserved hypothetical protein [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295896734|gb|EFG76368.1| conserved hypothetical protein [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=248

 Score = 84.0 bits (206),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 62/92 (68%), Positives = 68/92 (74%), Gaps = 1/92 (1%)

Query  5    ECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYVVVSA  64
            E    SRR HV RLA+F   LL LFYLVAVARVI VD VR  +V ATGP AP+ YV VSA
Sbjct  17   ESEPTSRRTHVARLAVFVVFLLVLFYLVAVARVIDVDEVRR-VVSATGPAAPVTYVAVSA  75

Query  65   ALGALFVPGPILAAGSGVLFGPLLDTFVTLPA  96
             LGALFVPG +LAA SG+LFGP+L  FVTL A
Sbjct  76   VLGALFVPGAVLAAASGLLFGPVLGVFVTLGA  107


>gi|284042519|ref|YP_003392859.1| hypothetical protein Cwoe_1052 [Conexibacter woesei DSM 14684]
 gi|283946740|gb|ADB49484.1| SNARE associated Golgi protein-related protein [Conexibacter 
woesei DSM 14684]
Length=243

 Score = 51.6 bits (122),  Expect = 7e-05, Method: Compositional matrix adjust.
 Identities = 37/83 (45%), Positives = 49/83 (60%), Gaps = 4/83 (4%)

Query  11   RRRHVLRLALFAGI---LLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYVVVSAALG  67
            RR  ++ LA   G+   ++ LF + A    +  +GVR A V   GP+APL +VVVSA L 
Sbjct  26   RRAQLVALARLLGLGAFVVALFVVAASVFGLSSEGVRDA-VDGVGPLAPLVFVVVSAGLT  84

Query  68   ALFVPGPILAAGSGVLFGPLLDT  90
               VPGP+LA  SG+LFG  L T
Sbjct  85   VACVPGPLLAGASGLLFGTALGT  107


>gi|312882173|ref|ZP_07741921.1| AcrB/AcrD/AcrF family protein [Vibrio caribbenthicus ATCC BAA-2122]
 gi|309370135|gb|EFP97639.1| AcrB/AcrD/AcrF family protein [Vibrio caribbenthicus ATCC BAA-2122]
Length=1035

 Score = 48.9 bits (115),  Expect = 4e-04, Method: Composition-based stats.
 Identities = 38/117 (33%), Positives = 59/117 (51%), Gaps = 10/117 (8%)

Query  18   LALFAGIL-LGLFYLVA------VARVIHVDGV--RSAIVVATGPIAPLAYVVVSAALGA  68
            L +FA +L +GL    A      V RV+H DG+  R A   + G I+  A V ++  L A
Sbjct  392  LTMFAMVLAIGLLVDDAIVVVENVERVMHEDGLSPREATHKSMGQISS-ALVGIALTLSA  450

Query  69   LFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIASMHRSNG  125
            +FVP   ++  +GV++     T +T  A SA     +TP  C   + PI +  ++NG
Sbjct  451  VFVPMAFMSGSTGVIYRQFSVTIITAMALSAVVALVLTPALCATMLKPIKNEKQANG  507


>gi|345125339|gb|EGW55209.1| rhodanese domain protein [endosymbiont of Tevnia jerichonana 
(vent Tica)]
Length=333

 Score = 48.1 bits (113),  Expect = 6e-04, Method: Compositional matrix adjust.
 Identities = 28/76 (37%), Positives = 38/76 (50%), Gaps = 1/76 (1%)

Query  39   HVD-GVRSAIVVATGPIAPLAYVVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAF  97
            H+D G     V   GP APL ++V+ A    LF+PG ++    G LFGP+L TF  L   
Sbjct  27   HIDAGALQQWVEQAGPAAPLLFMVIYAIGTVLFLPGSVMTLAGGALFGPVLGTFYNLTGA  86

Query  98   SAGAQAGMTPRRCWVS  113
            + GA       R + S
Sbjct  87   TIGAVLAFLIARFFTS  102


>gi|95931277|ref|ZP_01313995.1| protein of unknown function DUF224, cysteine-rich region [Desulfuromonas 
acetoxidans DSM 684]
 gi|95132671|gb|EAT14352.1| protein of unknown function DUF224, cysteine-rich region [Desulfuromonas 
acetoxidans DSM 684]
Length=602

 Score = 46.2 bits (108),  Expect = 0.003, Method: Compositional matrix adjust.
 Identities = 35/101 (35%), Positives = 49/101 (49%), Gaps = 2/101 (1%)

Query  1    MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIAPLAYV  60
            MT  E    SR   V+ LAL    ++ L  +   A  +  + +R  I   TG  APL ++
Sbjct  375  MTTTEQKKKSRLGQVIVLALLIAAIVTL-KMTGAADYLQPEKLRDWIA-GTGFWAPLIFM  432

Query  61   VVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGA  101
            V+  A  ALF+PG  L    G+LFGP      T+   +AGA
Sbjct  433  VLYTAAPALFLPGLPLTILGGILFGPFWGVVYTITGATAGA  473


>gi|300864069|ref|ZP_07108969.1| conserved membrane hypothetical protein [Oscillatoria sp. PCC 
6506]
 gi|300337948|emb|CBN54115.1| conserved membrane hypothetical protein [Oscillatoria sp. PCC 
6506]
Length=238

 Score = 42.4 bits (98),  Expect = 0.042, Method: Compositional matrix adjust.
 Identities = 27/86 (32%), Positives = 45/86 (53%), Gaps = 6/86 (6%)

Query  3   DNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRS---AIVVATGPIAPLAY  59
           DN+   D  +    +L L  GIL  +  L+  A+  ++ G+      ++   GP  P+A+
Sbjct  2   DNQ--PDKNQPSSNKLKLIFGIL-SIIALIVGAKFFNLQGILKDSLELIANLGPWGPVAF  58

Query  60  VVVSAALGALFVPGPILAAGSGVLFG  85
           ++V      LF+PG +L  G+GVLFG
Sbjct  59  ILVYILATVLFIPGSLLTLGAGVLFG  84


>gi|117924412|ref|YP_865029.1| rhodanese [Magnetococcus sp. MC-1]
 gi|117608168|gb|ABK43623.1| Rhodanese domain protein [Magnetococcus sp. MC-1]
Length=325

 Score = 41.6 bits (96),  Expect = 0.057, Method: Compositional matrix adjust.
 Identities = 22/50 (44%), Positives = 30/50 (60%), Gaps = 0/50 (0%)

Query  52   GPIAPLAYVVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGA  101
            GP+A LA++V+ A     F+PG +L    G LFGP+L T V L   + GA
Sbjct  43   GPLAWLAFIVLYAVATVAFLPGSLLTLVGGALFGPILGTLVNLTGATLGA  92


>gi|334119426|ref|ZP_08493512.1| SNARE associated protein [Microcoleus vaginatus FGP-2]
 gi|333458214|gb|EGK86833.1| SNARE associated protein [Microcoleus vaginatus FGP-2]
Length=241

 Score = 41.2 bits (95),  Expect = 0.086, Method: Compositional matrix adjust.
 Identities = 29/88 (33%), Positives = 48/88 (55%), Gaps = 5/88 (5%)

Query  1   MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGV-RSAI--VVATGPIAPL  57
           M D+  P ++  R   R  L  GI L +  L+A  + +   G+ ++A+  + + GP  P 
Sbjct  1   MNDSRSPDENPPRSN-RWKLILGIGLAV-ALIAATKFLDFQGILKNALESIASLGPWGPA  58

Query  58  AYVVVSAALGALFVPGPILAAGSGVLFG  85
           A++++      LF+PG +L  GSGVLFG
Sbjct  59  AFILIYIVATVLFIPGSLLTLGSGVLFG  86


>gi|114319913|ref|YP_741596.1| hypothetical protein Mlg_0752 [Alkalilimnicola ehrlichii MLHE-1]
 gi|114226307|gb|ABI56106.1| conserved hypothetical protein [Alkalilimnicola ehrlichii MLHE-1]
Length=229

 Score = 40.8 bits (94),  Expect = 0.11, Method: Compositional matrix adjust.
 Identities = 36/93 (39%), Positives = 50/93 (54%), Gaps = 8/93 (8%)

Query  13   RHVLRLALFAGILLGLFYLVAVARVI----HVDGVRSAIVVATGPIAPLAYVVVSAALGA  68
            R ++R AL   I+LGL  ++A+A  +     VD +R A +   GP APLA++   A    
Sbjct  3    RRLIRKAL---IVLGLTLVIALAWALRDHLQVDVLR-ATLDDLGPWAPLAFMGAYAIAAV  58

Query  69   LFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGA  101
             FVPG +     GVLFGPL  T  +L   + GA
Sbjct  59   GFVPGSVFTLAGGVLFGPLWGTLYSLIGATVGA  91


>gi|17232678|ref|NP_489226.1| hypothetical protein alr5186 [Nostoc sp. PCC 7120]
 gi|17134325|dbj|BAB76885.1| alr5186 [Nostoc sp. PCC 7120]
Length=250

 Score = 40.4 bits (93),  Expect = 0.14, Method: Compositional matrix adjust.
 Identities = 29/104 (28%), Positives = 48/104 (47%), Gaps = 9/104 (8%)

Query  1    MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVV---ATGPIAPL  57
            M   E    +R+  +L + L   IL      + VAR  ++  +   +++   + G   P+
Sbjct  1    MIPKEQTRFNRKHRLLLIGLTIAIL------IIVARQFNIQALLQTLILWVQSLGFFGPI  54

Query  58   AYVVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGA  101
            AY+++      LF+PG IL   SG LFG    +   L A + GA
Sbjct  55   AYMIIYNLATLLFIPGSILTLKSGCLFGVFWGSVYVLIAATVGA  98


>gi|302036507|ref|YP_003796829.1| hypothetical protein NIDE1145 [Candidatus Nitrospira defluvii]
 gi|300604571|emb|CBK40903.1| conserved membrane protein of unknown function, DedA family [Candidatus 
Nitrospira defluvii]
Length=245

 Score = 39.7 bits (91),  Expect = 0.23, Method: Compositional matrix adjust.
 Identities = 34/114 (30%), Positives = 53/114 (47%), Gaps = 13/114 (11%)

Query  2    TDNECPADSRRRHV--LRLALFAGILLGLFYLVAVARVIHVDGVRS------AIVVATGP  53
            T  E P+ S+R  +  L L +F G+ L  F+   + + + +DG++S      A   A  P
Sbjct  10   TSVESPSSSKRAGLGKLMLGIFVGLSLAAFFYFDLGQYLSLDGLKSNRARLLAFTEANYP  69

Query  54   IAPLAYVVVSAALGALFVP-GPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMT  106
            +A   +V+    +  L +P G I+    G LFG LL T       + GA  G T
Sbjct  70   VAVAMFVLAYCVVVGLSLPGGAIMTLAGGFLFGSLLGTLYV----NVGATVGAT  119


>gi|75908987|ref|YP_323283.1| hypothetical protein Ava_2775 [Anabaena variabilis ATCC 29413]
 gi|75702712|gb|ABA22388.1| DedA [Anabaena variabilis ATCC 29413]
Length=250

 Score = 39.7 bits (91),  Expect = 0.26, Method: Compositional matrix adjust.
 Identities = 27/104 (26%), Positives = 47/104 (46%), Gaps = 9/104 (8%)

Query  1    MTDNECPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVV---ATGPIAPL  57
            M   E    +R+  +L + L   +L      + +AR  ++  +   ++    + G   P+
Sbjct  1    MVPKEQTRFNRKHKLLLMGLAIAVL------IVIARQFNIQSLFQTLIFWVQSLGFFGPI  54

Query  58   AYVVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGA  101
            AY+++      LF+PG IL   SG LFG    +   L A + GA
Sbjct  55   AYIIIYNLATLLFIPGSILTLKSGCLFGVFWGSVYVLIAATTGA  98


>gi|313896321|ref|ZP_07829874.1| acriflavine resistance protein B [Selenomonas sp. oral taxon 
137 str. F0430]
 gi|320529285|ref|ZP_08030375.1| putative inner membrane multidrug efflux protein BpeB [Selenomonas 
artemidis F0399]
 gi|312975120|gb|EFR40582.1| acriflavine resistance protein B [Selenomonas sp. oral taxon 
137 str. F0430]
 gi|320138459|gb|EFW30351.1| putative inner membrane multidrug efflux protein BpeB [Selenomonas 
artemidis F0399]
Length=1063

 Score = 38.1 bits (87),  Expect = 0.65, Method: Composition-based stats.
 Identities = 33/111 (30%), Positives = 47/111 (43%), Gaps = 17/111 (15%)

Query  18   LALFAGIL-LGLFY---LVAVARVIH--------VDGVRSAIVVATGPIAPLAYVVVSAA  65
            L LFA +L +GL     +V +  V H        +D    A+    GP+  +A+V     
Sbjct  393  LTLFAMVLAIGLVVDDAIVVIENVEHHMESGLSPIDATERAMAEVQGPVVAIAFV-----  447

Query  66   LGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAP  116
            L A+FVP   L    GVL+     T     A SA     +TP  C + + P
Sbjct  448  LAAVFVPVAFLGGMMGVLYKQFALTIAISMALSAFVALTLTPALCALMLKP  498


>gi|148263625|ref|YP_001230331.1| hypothetical protein Gura_1562 [Geobacter uraniireducens Rf4]
 gi|146397125|gb|ABQ25758.1| protein of unknown function DUF224, cysteine-rich region domain 
protein [Geobacter uraniireducens Rf4]
Length=623

 Score = 38.1 bits (87),  Expect = 0.74, Method: Compositional matrix adjust.
 Identities = 25/85 (30%), Positives = 41/85 (49%), Gaps = 8/85 (9%)

Query  25   LLGLFYLVAVARVIHVDGV--------RSAIVVATGPIAPLAYVVVSAALGALFVPGPIL  76
            L+ L  LVA    +H+ G           A++ + G +AP  Y+++ A    LF+PG  +
Sbjct  407  LIFLVLLVAAVAGVHLSGAAQYLQQEKLQALIASYGVLAPAIYILLYALAPVLFLPGLPI  466

Query  77   AAGSGVLFGPLLDTFVTLPAFSAGA  101
                G+LFGP+     T+   + GA
Sbjct  467  TIVGGILFGPVWGVVYTITGATIGA  491


>gi|186683627|ref|YP_001866823.1| hypothetical protein Npun_R3472 [Nostoc punctiforme PCC 73102]
 gi|186466079|gb|ACC81880.1| DedA [Nostoc punctiforme PCC 73102]
Length=264

 Score = 37.7 bits (86),  Expect = 0.80, Method: Compositional matrix adjust.
 Identities = 28/90 (32%), Positives = 42/90 (47%), Gaps = 7/90 (7%)

Query  31   LVAVARVIHVDGVRSAIVV---ATGPIAPLAYVVVSAALGALFVPGPILAAGSGVLFGPL  87
            L+  A+ ++  G+  A V+   + G + P+AY+V+      LF+PG +L    G LFG  
Sbjct  34   LIIAAKQLNFQGLLQASVIWVESLGVLGPIAYIVIYNLATLLFIPGSLLTLKGGCLFGVF  93

Query  88   LDTFVTLPAFSAGAQ----AGMTPRRCWVS  113
              +   L A   GA      G    R WVS
Sbjct  94   WGSIYVLIAAMVGATLAFIIGRYLSRDWVS  123


>gi|334127847|ref|ZP_08501749.1| RND superfamily resistance-nodulation-cell division:proton (H+) 
antiporter [Centipeda periodontii DSM 2778]
 gi|333388568|gb|EGK59742.1| RND superfamily resistance-nodulation-cell division:proton (H+) 
antiporter [Centipeda periodontii DSM 2778]
Length=1063

 Score = 37.7 bits (86),  Expect = 0.93, Method: Composition-based stats.
 Identities = 33/111 (30%), Positives = 47/111 (43%), Gaps = 17/111 (15%)

Query  18   LALFAGIL-LGLFY---LVAVARVIH--------VDGVRSAIVVATGPIAPLAYVVVSAA  65
            L LFA +L +GL     +V +  V H        +D    A+    GP+  +A+V     
Sbjct  393  LTLFAMVLAIGLVVDDAIVVIENVEHHMASGLTPIDATERAMSEVQGPVVAIAFV-----  447

Query  66   LGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAP  116
            L A+FVP   L    GVL+     T     A SA     +TP  C + + P
Sbjct  448  LAAVFVPVAFLGGMMGVLYKQFALTIAISMAISAFVALSLTPALCALMLKP  498


>gi|90581492|ref|ZP_01237286.1| AcrB/AcrD/AcrF family protein [Vibrio angustum S14]
 gi|90437353|gb|EAS62550.1| AcrB/AcrD/AcrF family protein [Vibrio angustum S14]
Length=1043

 Score = 37.7 bits (86),  Expect = 0.95, Method: Composition-based stats.
 Identities = 34/113 (31%), Positives = 52/113 (47%), Gaps = 18/113 (15%)

Query  18   LALFAGIL-LGLFYLVA------VARVIHVDGV------RSAIVVATGPIAPLAYVVVSA  64
            L +FA +L +GL    A      V RV+H +G+      R ++   TG     A V ++ 
Sbjct  393  LTMFAMVLAIGLLVDDAIVVVENVERVMHEEGLNAVEATRKSMDQITG-----ALVGIAM  447

Query  65   ALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPI  117
             L A+FVP   ++  +GV++     T VT  A S      +TP  C   + PI
Sbjct  448  TLSAVFVPMAFMSGSTGVIYRQFSITIVTAMALSVMVALILTPALCATMLKPI  500


>gi|89073891|ref|ZP_01160398.1| AcrB/AcrD/AcrF family protein [Photobacterium sp. SKA34]
 gi|89050426|gb|EAR55927.1| AcrB/AcrD/AcrF family protein [Photobacterium sp. SKA34]
Length=1043

 Score = 37.7 bits (86),  Expect = 0.95, Method: Composition-based stats.
 Identities = 34/113 (31%), Positives = 52/113 (47%), Gaps = 18/113 (15%)

Query  18   LALFAGIL-LGLFYLVA------VARVIHVDGV------RSAIVVATGPIAPLAYVVVSA  64
            L +FA +L +GL    A      V RV+H +G+      R ++   TG     A V ++ 
Sbjct  393  LTMFAMVLAIGLLVDDAIVVVENVERVMHEEGLNAVEATRKSMDQITG-----ALVGIAM  447

Query  65   ALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPI  117
             L A+FVP   ++  +GV++     T VT  A S      +TP  C   + PI
Sbjct  448  TLSAVFVPMAFMSGSTGVIYRQFSITIVTAMALSVMVALILTPALCATMLKPI  500


>gi|116749667|ref|YP_846354.1| hypothetical protein Sfum_2237 [Syntrophobacter fumaroxidans 
MPOB]
 gi|116698731|gb|ABK17919.1| conserved hypothetical protein [Syntrophobacter fumaroxidans 
MPOB]
Length=266

 Score = 37.7 bits (86),  Expect = 0.96, Method: Compositional matrix adjust.
 Identities = 37/106 (35%), Positives = 47/106 (45%), Gaps = 10/106 (9%)

Query  13   RHVLRLALFAGILLGLFYLVAVARVIHV-DGVRSAIVVATGPIAPLAYVVVSAALGALFV  71
            R +L   LFA + + LF+L     V+ V +  R       GP+ PL  V+       L +
Sbjct  19   RILLACLLFAAVAVSLFFLPVKKYVLEVLEWTRH-----LGPLGPLVVVLSFLVACVLPI  73

Query  72   PGPILAAGSGVLFGPLLDTFVTLPAFSAGA----QAGMTPRRCWVS  113
            PG ILA GSG LFGP   T       + GA      G T  R WV 
Sbjct  74   PGSILAMGSGFLFGPFGGTATAATGCTLGACFAFILGRTIARSWVE  119


>gi|260886616|ref|ZP_05897879.1| multidrug efflux RND transporter MexF [Selenomonas sputigena 
ATCC 35185]
 gi|330839550|ref|YP_004414130.1| transporter, hydrophobe/amphiphile efflux-1 (HAE1) family [Selenomonas 
sputigena ATCC 35185]
 gi|260863759|gb|EEX78259.1| multidrug efflux RND transporter MexF [Selenomonas sputigena 
ATCC 35185]
 gi|329747314|gb|AEC00671.1| transporter, hydrophobe/amphiphile efflux-1 (HAE1) family [Selenomonas 
sputigena ATCC 35185]
Length=1065

 Score = 37.7 bits (86),  Expect = 0.97, Method: Composition-based stats.
 Identities = 34/113 (31%), Positives = 48/113 (43%), Gaps = 17/113 (15%)

Query  18   LALFAGIL-LGLFY---LVAVARVIH--------VDGVRSAIVVATGPIAPLAYVVVSAA  65
            L LFA +L +GL     +V +  V H        +D    A+    GP+  +A+V     
Sbjct  393  LTLFAMVLAIGLVVDDAIVVIENVEHHMEEGLNVIDATERAMDEVQGPVVAIAFV-----  447

Query  66   LGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIA  118
            L A+FVP   L    GVL+     T     A SA     +TP  C + + P A
Sbjct  448  LAAVFVPVAFLGGMMGVLYKQFALTIAISMAISAFVALSLTPALCALILKPHA  500


>gi|338849388|gb|AEJ27599.1| RND efflux system inner membrane transporter protein [Paracoccus 
denitrificans SD1]
Length=430

 Score = 37.7 bits (86),  Expect = 0.98, Method: Compositional matrix adjust.
 Identities = 33/112 (30%), Positives = 51/112 (46%), Gaps = 5/112 (4%)

Query  18   LALFAGILL--GLFYLVAVARVIHVDGV--RSAIVVATGPIAPLAYVVVSAALGALFVPG  73
            + L  GIL+   +  +  V R++  +G+  R A   A G I+  A V ++  L A+FVP 
Sbjct  139  MVLAIGILVDDAIVVIENVERIMATEGLPPREATQKAMGQISG-AIVGITLVLAAVFVPM  197

Query  74   PILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIASMHRSNG  125
                  SG+++     T V    FSA     +TP  C   + PI+  H   G
Sbjct  198  AFFPGSSGIIYRQFALTMVVSILFSAFLALTLTPALCATFLKPISGHHEKKG  249


>gi|292670164|ref|ZP_06603590.1| RND superfamily drug:proton (H+) antiporter [Selenomonas noxia 
ATCC 43541]
 gi|292648116|gb|EFF66088.1| RND superfamily drug:proton (H+) antiporter [Selenomonas noxia 
ATCC 43541]
Length=1063

 Score = 37.4 bits (85),  Expect = 1.3, Method: Composition-based stats.
 Identities = 33/111 (30%), Positives = 47/111 (43%), Gaps = 17/111 (15%)

Query  18   LALFAGIL-LGLFY---LVAVARVIH--------VDGVRSAIVVATGPIAPLAYVVVSAA  65
            L LFA +L +GL     +V +  V H        +D    A+    GP+  +A+V     
Sbjct  393  LTLFAMVLAIGLVVDDAIVVIENVEHHMESGLSPIDATERAMDEVQGPVVAIAFV-----  447

Query  66   LGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAP  116
            L A+FVP   L    GVL+     T     A SA     +TP  C + + P
Sbjct  448  LAAVFVPVAFLGGMMGVLYKQFALTIAISMALSAFVALTLTPALCAMMLKP  498


>gi|238926903|ref|ZP_04658663.1| possible acridine efflux pump [Selenomonas flueggei ATCC 43531]
 gi|238885137|gb|EEQ48775.1| possible acridine efflux pump [Selenomonas flueggei ATCC 43531]
Length=577

 Score = 37.4 bits (85),  Expect = 1.3, Method: Compositional matrix adjust.
 Identities = 34/111 (31%), Positives = 47/111 (43%), Gaps = 17/111 (15%)

Query  18   LALFAGIL-LGLFY---LVAVARVIH--------VDGVRSAIVVATGPIAPLAYVVVSAA  65
            L LFA +L +GL     +V +  V H        VD    A+    GP+  +A+V     
Sbjct  393  LTLFAMVLAIGLVVDDAIVVIENVEHHMESGLSPVDATERAMAEVQGPVVAIAFV-----  447

Query  66   LGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAP  116
            L A+FVP   L    GVL+     T     A SA     +TP  C + + P
Sbjct  448  LAAVFVPVAFLGGMMGVLYKQFALTIAIAMALSAFVALTLTPALCAMMLKP  498


>gi|304436757|ref|ZP_07396725.1| RND superfamily drug:proton (H+) antiporter [Selenomonas sp. 
oral taxon 149 str. 67H29BP]
 gi|304370237|gb|EFM23894.1| RND superfamily drug:proton (H+) antiporter [Selenomonas sp. 
oral taxon 149 str. 67H29BP]
Length=1063

 Score = 37.0 bits (84),  Expect = 1.5, Method: Composition-based stats.
 Identities = 33/111 (30%), Positives = 46/111 (42%), Gaps = 17/111 (15%)

Query  18   LALFAGIL-LGLFY---LVAVARVIH--------VDGVRSAIVVATGPIAPLAYVVVSAA  65
            L LFA +L +GL     +V +  V H        VD    A+    GP+  +A+V     
Sbjct  393  LTLFAMVLAIGLVVDDAIVVIENVEHHMESGLSPVDATERAMAEVQGPVVAIAFV-----  447

Query  66   LGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAP  116
            L A+FVP   L    GVL+     T       SA     +TP  C + + P
Sbjct  448  LAAVFVPVAFLGGMMGVLYKQFALTIAIAMGLSAFVALTLTPALCALMLKP  498


>gi|338811703|ref|ZP_08623908.1| transporter, hydrophobe/amphiphile efflux-1 (HAE1) family protein 
[Acetonema longum DSM 6540]
 gi|337276240|gb|EGO64672.1| transporter, hydrophobe/amphiphile efflux-1 (HAE1) family protein 
[Acetonema longum DSM 6540]
Length=1047

 Score = 36.6 bits (83),  Expect = 1.9, Method: Composition-based stats.
 Identities = 23/82 (29%), Positives = 38/82 (47%), Gaps = 5/82 (6%)

Query  35   ARVIHVDGVRSAIVVATGPIAPLAYVVVSAALGALFVPGPILAAGSGVLFGPLLDTFVTL  94
            +R+  ++  R A+   +GP+  +A+V     L A+FVP   +    GVL+     T    
Sbjct  423  SRLTPLEATRRAMDEVSGPVIAIAFV-----LAAVFVPVAFIGGMVGVLYRQFALTIAVS  477

Query  95   PAFSAGAQAGMTPRRCWVSIAP  116
             A SA     +TP  C + + P
Sbjct  478  MALSALVALSLTPALCALLLKP  499


>gi|32476849|ref|NP_869843.1| hypothetical protein RB11207 [Rhodopirellula baltica SH 1]
 gi|32447397|emb|CAD78986.1| conserved hypothetical protein [Rhodopirellula baltica SH 1]
Length=538

 Score = 36.6 bits (83),  Expect = 2.0, Method: Compositional matrix adjust.
 Identities = 31/122 (26%), Positives = 55/122 (46%), Gaps = 4/122 (3%)

Query  6    CPADSRRRHVLRLALFAGILLGLFYLVAVARVIHVDGVRSAIVVATGPIA---PLAYVVV  62
             PA++    + +   +  I + +  L+ + R +  D V SA+    G +    P+  V++
Sbjct  1    MPAETTAAKINQYVRWGSIAIVVVSLLVIIRTLPFDVVTSAMNEWIGSLGWWGPVVLVLL  60

Query  63   SAALGALFVPGPILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIASMHR  122
                  LFVPG IL   +G +FG L+ T V     + GA       R +V+   +A + +
Sbjct  61   YIVATVLFVPGTILTLAAGAIFGLLVGTIVVSIGSTIGAALAFLISR-YVARERVAKLAK  119

Query  123  SN  124
             N
Sbjct  120  DN  121


>gi|225025203|ref|ZP_03714395.1| hypothetical protein EIKCOROL_02100 [Eikenella corrodens ATCC 
23834]
 gi|224941961|gb|EEG23170.1| hypothetical protein EIKCOROL_02100 [Eikenella corrodens ATCC 
23834]
Length=1082

 Score = 36.6 bits (83),  Expect = 2.1, Method: Composition-based stats.
 Identities = 28/90 (32%), Positives = 44/90 (49%), Gaps = 3/90 (3%)

Query  34   VARVIHVDGV--RSAIVVATGPIAPLAYVVVSAALGALFVPGPILAAGSGVLFGPLLDTF  91
            V R++  +G+  R A   A G I+  A V ++A L ++FVP  + +  +G ++     T 
Sbjct  414  VERIMSEEGLPPREATHKAMGQISG-AVVGITAVLISVFVPLAMFSGATGKIYQQFAITM  472

Query  92   VTLPAFSAGAQAGMTPRRCWVSIAPIASMH  121
            V   AFSA     +TP  C   + PI   H
Sbjct  473  VLSIAFSAFLALSLTPALCASLLKPIEKGH  502


>gi|340029272|ref|ZP_08665335.1| hydrophobe/amphiphile efflux-1 (HAE1) family protein [Paracoccus 
sp. TRP]
Length=1041

 Score = 36.6 bits (83),  Expect = 2.2, Method: Composition-based stats.
 Identities = 32/112 (29%), Positives = 49/112 (44%), Gaps = 5/112 (4%)

Query  18   LALFAGILL--GLFYLVAVARVIHVDGV--RSAIVVATGPIAPLAYVVVSAALGALFVPG  73
            + L  GIL+   +  +  V R++  +G+  R A   A   I+  A V ++  L A+FVP 
Sbjct  398  MVLAIGILVDDAIVVIENVERIMASEGLPPREATEKAMDQISG-AIVGITLVLAAVFVPM  456

Query  74   PILAAGSGVLFGPLLDTFVTLPAFSAGAQAGMTPRRCWVSIAPIASMHRSNG  125
                  SG+++     T V    FSA     +TP  C   + PI   H   G
Sbjct  457  AFFPGSSGIIYRQFALTMVVSILFSAFLALTLTPALCATFLKPINGHHEKKG  508



Lambda     K      H
   0.326    0.136    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 208621361780


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40