BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv2333c
Length=537
Score E
Sequences producing significant alignments: (Bits) Value
gi|15609470|ref|NP_216849.1| integral membrane transport protein... 1063 0.0
gi|15841836|ref|NP_336873.1| drug transporter [Mycobacterium tub... 1060 0.0
gi|298525817|ref|ZP_07013226.1| conserved integral membrane tran... 1058 0.0
gi|289443850|ref|ZP_06433594.1| drug transporter [Mycobacterium ... 999 0.0
gi|31793517|ref|NP_856010.1| integral membrane transport protein... 996 0.0
gi|183983622|ref|YP_001851913.1| integral membrane transport pro... 803 0.0
gi|289575025|ref|ZP_06455252.1| LOW QUALITY PROTEIN: drug transp... 550 2e-154
gi|118617132|ref|YP_905464.1| integral membrane transport protei... 477 2e-132
gi|183983780|ref|YP_001852071.1| integral membrane transport pro... 411 2e-112
gi|118618990|ref|YP_907322.1| integral membrane transport protei... 404 2e-110
gi|253798462|ref|YP_003031463.1| membrane transporter [Mycobacte... 387 2e-105
gi|15609596|ref|NP_216975.1| integral membrane transport protein... 387 2e-105
gi|15841983|ref|NP_337020.1| drug transporter [Mycobacterium tub... 387 2e-105
gi|254232593|ref|ZP_04925920.1| hypothetical protein TBCG_02400 ... 387 2e-105
gi|307085143|ref|ZP_07494256.1| conserved membrane transporter [... 387 3e-105
gi|31793640|ref|NP_856133.1| integral membrane transport protein... 385 1e-104
gi|145594704|ref|YP_001159001.1| EmrB/QacA family drug resistanc... 385 1e-104
gi|308232137|ref|ZP_07415066.2| conserved membrane transporter [... 384 2e-104
gi|240169656|ref|ZP_04748315.1| integral membrane transport prot... 382 8e-104
gi|159037939|ref|YP_001537192.1| EmrB/QacA family drug resistanc... 366 6e-99
gi|294994433|ref|ZP_06800124.1| membrane transporter [Mycobacter... 332 1e-88
gi|226304701|ref|YP_002764659.1| drug resistance efflux protein ... 289 8e-76
gi|229490123|ref|ZP_04383971.1| efflux membrane protein [Rhodoco... 289 1e-75
gi|312200663|ref|YP_004020724.1| drug resistance transporter Emr... 287 4e-75
gi|298251605|ref|ZP_06975408.1| drug resistance transporter, Emr... 285 2e-74
gi|254382912|ref|ZP_04998268.1| efflux membrane protein [Strepto... 282 9e-74
gi|256391255|ref|YP_003112819.1| drug resistance transporter Emr... 282 9e-74
gi|288918903|ref|ZP_06413246.1| drug resistance transporter, Emr... 279 7e-73
gi|297194492|ref|ZP_06911890.1| efflux membrane protein [Strepto... 276 6e-72
gi|111220069|ref|YP_710863.1| putative efflux membrane protein [... 273 5e-71
gi|209515436|ref|ZP_03264302.1| drug resistance transporter, Emr... 273 8e-71
gi|329934688|ref|ZP_08284729.1| efflux membrane protein [Strepto... 272 9e-71
gi|29832191|ref|NP_826825.1| efflux membrane protein [Streptomyc... 272 1e-70
gi|297199530|ref|ZP_06916927.1| efflux protein [Streptomyces svi... 271 3e-70
gi|302560756|ref|ZP_07313098.1| drug resistance transporter, Emr... 270 5e-70
gi|291439775|ref|ZP_06579165.1| efflux protein [Streptomyces gha... 270 7e-70
gi|340776391|ref|ZP_08696334.1| putative efflux membrane protein... 269 7e-70
gi|294812525|ref|ZP_06771168.1| Efflux membrane protein [Strepto... 268 2e-69
gi|254389019|ref|ZP_05004249.1| efflux membrane protein [Strepto... 267 3e-69
gi|307727391|ref|YP_003910604.1| drug resistance transporter Emr... 267 4e-69
gi|158318319|ref|YP_001510827.1| EmrB/QacA family drug resistanc... 266 5e-69
gi|338778012|gb|EGP42499.1| drug resistance MFS transporter, dru... 266 1e-68
gi|298246882|ref|ZP_06970687.1| drug resistance transporter, Emr... 265 1e-68
gi|296136482|ref|YP_003643724.1| major facilitator superfamily M... 265 2e-68
gi|337764480|emb|CCB73189.1| putative efflux protein [Streptomyc... 264 3e-68
gi|298251556|ref|ZP_06975359.1| drug resistance transporter, Emr... 263 6e-68
gi|345015034|ref|YP_004817388.1| EmrB/QacA subfamily drug resist... 263 8e-68
gi|295680907|ref|YP_003609481.1| major facilitator superfamily M... 263 9e-68
gi|336116572|ref|YP_004571339.1| putative drug resistance transp... 260 4e-67
gi|32141172|ref|NP_733574.1| efflux protein [Streptomyces coelic... 260 4e-67
>gi|15609470|ref|NP_216849.1| integral membrane transport protein [Mycobacterium tuberculosis
H37Rv]
gi|148662161|ref|YP_001283684.1| putative integral membrane transport protein [Mycobacterium tuberculosis
H37Ra]
gi|148823534|ref|YP_001288288.1| integral membrane transport protein [Mycobacterium tuberculosis
F11]
41 more sequence titles
Length=537
Score = 1063 bits (2748), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 537/537 (100%), Positives = 537/537 (100%), Gaps = 0/537 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM
Sbjct 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV
Sbjct 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL
Sbjct 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF
Sbjct 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
Query 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL
Sbjct 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
Query 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL
Sbjct 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE
Sbjct 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
Query 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL
Sbjct 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
Query 481 LVATATLAVVFLAGWRWFPRDVHTAGSDLSERLPTAMTVECAVSHMPGATWCRLWPA 537
LVATATLAVVFLAGWRWFPRDVHTAGSDLSERLPTAMTVECAVSHMPGATWCRLWPA
Sbjct 481 LVATATLAVVFLAGWRWFPRDVHTAGSDLSERLPTAMTVECAVSHMPGATWCRLWPA 537
>gi|15841836|ref|NP_336873.1| drug transporter [Mycobacterium tuberculosis CDC1551]
gi|254232477|ref|ZP_04925804.1| hypothetical protein TBCG_02278 [Mycobacterium tuberculosis C]
gi|254365113|ref|ZP_04981159.1| conserved integral membrane transport protein [Mycobacterium
tuberculosis str. Haarlem]
12 more sequence titles
Length=537
Score = 1060 bits (2740), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 536/537 (99%), Positives = 536/537 (99%), Gaps = 0/537 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM
Sbjct 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
SAATLADL GRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV
Sbjct 61 SAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL
Sbjct 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF
Sbjct 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
Query 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL
Sbjct 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
Query 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL
Sbjct 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE
Sbjct 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
Query 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL
Sbjct 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
Query 481 LVATATLAVVFLAGWRWFPRDVHTAGSDLSERLPTAMTVECAVSHMPGATWCRLWPA 537
LVATATLAVVFLAGWRWFPRDVHTAGSDLSERLPTAMTVECAVSHMPGATWCRLWPA
Sbjct 481 LVATATLAVVFLAGWRWFPRDVHTAGSDLSERLPTAMTVECAVSHMPGATWCRLWPA 537
>gi|298525817|ref|ZP_07013226.1| conserved integral membrane transport protein [Mycobacterium
tuberculosis 94_M4241A]
gi|298495611|gb|EFI30905.1| conserved integral membrane transport protein [Mycobacterium
tuberculosis 94_M4241A]
Length=537
Score = 1058 bits (2735), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 535/537 (99%), Positives = 535/537 (99%), Gaps = 0/537 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM
Sbjct 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
SAATLADL GRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV
Sbjct 61 SAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL
Sbjct 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF
Sbjct 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
Query 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL
Sbjct 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
Query 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL
Sbjct 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE
Sbjct 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
Query 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL
Sbjct 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
Query 481 LVATATLAVVFLAGWRWFPRDVHTAGSDLSERLPTAMTVECAVSHMPGATWCRLWPA 537
LVATATLAVVFLAGWRWFPRDVHTAGSDLSERL TAMTVECAVSHMPGATWCRLWPA
Sbjct 481 LVATATLAVVFLAGWRWFPRDVHTAGSDLSERLATAMTVECAVSHMPGATWCRLWPA 537
>gi|289443850|ref|ZP_06433594.1| drug transporter [Mycobacterium tuberculosis T46]
gi|289447974|ref|ZP_06437718.1| conserved membrane transporter [Mycobacterium tuberculosis CPHL_A]
gi|289570466|ref|ZP_06450693.1| conserved membrane transporter [Mycobacterium tuberculosis T17]
9 more sequence titles
Length=523
Score = 999 bits (2583), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 507/508 (99%), Positives = 507/508 (99%), Gaps = 0/508 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM
Sbjct 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
SAATLADL GRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV
Sbjct 61 SAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL
Sbjct 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF
Sbjct 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
Query 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL
Sbjct 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
Query 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL
Sbjct 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE
Sbjct 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
Query 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL
Sbjct 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
Query 481 LVATATLAVVFLAGWRWFPRDVHTAGSD 508
LVATATLAVVFLAGWRWFPRDVHTAGSD
Sbjct 481 LVATATLAVVFLAGWRWFPRDVHTAGSD 508
>gi|31793517|ref|NP_856010.1| integral membrane transport protein [Mycobacterium bovis AF2122/97]
gi|121638220|ref|YP_978444.1| putative integral membrane transport protein [Mycobacterium bovis
BCG str. Pasteur 1173P2]
gi|224990714|ref|YP_002645401.1| putative integral membrane transport protein [Mycobacterium bovis
BCG str. Tokyo 172]
gi|31619110|emb|CAD97222.1| PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN [Mycobacterium
bovis AF2122/97]
gi|121493868|emb|CAL72343.1| Probable conserved integral membrane transport protein [Mycobacterium
bovis BCG str. Pasteur 1173P2]
gi|224773827|dbj|BAH26633.1| putative integral membrane transport protein [Mycobacterium bovis
BCG str. Tokyo 172]
gi|341602258|emb|CCC64932.1| probable conserved integral membrane transport protein [Mycobacterium
bovis BCG str. Moreau RDJ]
Length=523
Score = 996 bits (2576), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 506/508 (99%), Positives = 506/508 (99%), Gaps = 0/508 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM
Sbjct 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
SAATLADL GRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV
Sbjct 61 SAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL
Sbjct 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF
Sbjct 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
Query 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL
Sbjct 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
Query 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL
Sbjct 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE
Sbjct 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
Query 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL
Sbjct 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
Query 481 LVATATLAVVFLAGWRWFPRDVHTAGSD 508
LVATATLAVVFLAGWRWFPRDV TAGSD
Sbjct 481 LVATATLAVVFLAGWRWFPRDVQTAGSD 508
>gi|183983622|ref|YP_001851913.1| integral membrane transport protein [Mycobacterium marinum M]
gi|183176948|gb|ACC42058.1| conserved integral membrane transport protein [Mycobacterium
marinum M]
Length=518
Score = 803 bits (2073), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 418/500 (84%), Positives = 446/500 (90%), Gaps = 0/500 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
MNRTQLLT+ ATGLGLFMIFLDA IVNVALPDIQ +F VGEDGLQWVVA+YSLGMAVFIM
Sbjct 1 MNRTQLLTIFATGLGLFMIFLDAFIVNVALPDIQNTFGVGEDGLQWVVAAYSLGMAVFIM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
SAATLAD GRRRWYL+G++LFTLGSIACGLAPSIA+LT ARG QG GAA VSVTSLALV
Sbjct 61 SAATLADRYGRRRWYLMGIALFTLGSIACGLAPSIAMLTAARGIQGFGAATVSVTSLALV 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
SAAFP KEKARAIGIWTA+AS+GT TGPTLGGLLVD WGWRSIFYVN+PMG V+ LT+
Sbjct 121 SAAFPNPKEKARAIGIWTAVASVGTATGPTLGGLLVDTWGWRSIFYVNVPMGVFVILLTV 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
+V ES N RA R DLSGQ LFIV VGA VYAVIEGPQIGWTS + +L TAAVGCALF
Sbjct 181 GFVAESRNARAGRLDLSGQALFIVTVGAFVYAVIEGPQIGWTSPLILTLLMTAAVGCALF 240
Query 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
+WLE RS++PMMDLTLFRD+SYAL+I TICTVFFAVYGMLLLTTQFLQNVRGYTP TGL
Sbjct 241 LWLEGRSADPMMDLTLFRDSSYALSIGTICTVFFAVYGMLLLTTQFLQNVRGYTPGATGL 300
Query 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
MILPFSA VA+VSPLVG LV R+GARV IL GL +LMLGLL LI SEHRS ALVLVGLG
Sbjct 301 MILPFSAGVAVVSPLVGSLVARVGARVLILIGLGLLMLGLLTLIASEHRSWALVLVGLGF 360
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
CG+GVALCLTPITTVAMTAVP ERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE
Sbjct 361 CGTGVALCLTPITTVAMTAVPPERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
Query 421 PHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEEDFIEGIRVAL 480
PHLE AVPDPVQRH +AE+IIDSANPRAHVGGIVPRR I HRDPVAIAEEDFIEGIRVA
Sbjct 421 PHLEPAVPDPVQRHTIAEVIIDSANPRAHVGGIVPRREIVHRDPVAIAEEDFIEGIRVAF 480
Query 481 LVATATLAVVFLAGWRWFPR 500
+ATA+L VFLAGWRWFPR
Sbjct 481 FIATASLGFVFLAGWRWFPR 500
>gi|289575025|ref|ZP_06455252.1| LOW QUALITY PROTEIN: drug transporter [Mycobacterium tuberculosis
K85]
gi|289539456|gb|EFD44034.1| LOW QUALITY PROTEIN: drug transporter [Mycobacterium tuberculosis
K85]
Length=292
Score = 550 bits (1418), Expect = 2e-154, Method: Compositional matrix adjust.
Identities = 277/277 (100%), Positives = 277/277 (100%), Gaps = 0/277 (0%)
Query 232 TAAVGCALFVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVR 291
TAAVGCALFVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVR
Sbjct 1 TAAVGCALFVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVR 60
Query 292 GYTPSVTGLMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSS 351
GYTPSVTGLMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSS
Sbjct 61 GYTPSVTGLMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSS 120
Query 352 ALVLVGLGLCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVL 411
ALVLVGLGLCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVL
Sbjct 121 ALVLVGLGLCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVL 180
Query 412 AAWLSATLEPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEED 471
AAWLSATLEPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEED
Sbjct 181 AAWLSATLEPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDPVAIAEED 240
Query 472 FIEGIRVALLVATATLAVVFLAGWRWFPRDVHTAGSD 508
FIEGIRVALLVATATLAVVFLAGWRWFPRDVHTAGSD
Sbjct 241 FIEGIRVALLVATATLAVVFLAGWRWFPRDVHTAGSD 277
>gi|118617132|ref|YP_905464.1| integral membrane transport protein [Mycobacterium ulcerans Agy99]
gi|118569242|gb|ABL03993.1| conserved integral membrane transport protein [Mycobacterium
ulcerans Agy99]
Length=301
Score = 477 bits (1228), Expect = 2e-132, Method: Compositional matrix adjust.
Identities = 238/294 (81%), Positives = 258/294 (88%), Gaps = 0/294 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
MNRTQLLT+ ATGLGLFMIFLDA IVNVALPDIQ +F VGEDGLQWVVA+YSLGMAVFIM
Sbjct 1 MNRTQLLTIFATGLGLFMIFLDAFIVNVALPDIQNTFGVGEDGLQWVVAAYSLGMAVFIM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
SAATLAD GRRRWYL+G+ LFTLGSIACGLAPSIA+LT ARG QG GAA VSVTSLALV
Sbjct 61 SAATLADRYGRRRWYLMGIVLFTLGSIACGLAPSIAMLTAARGVQGFGAATVSVTSLALV 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
SAAFP KEKARAIGIWTA+AS+GT TGPTLGGLLVD WGWRSIFYVN+PMG V+ LT+
Sbjct 121 SAAFPNPKEKARAIGIWTAVASVGTATGPTLGGLLVDTWGWRSIFYVNVPMGVFVILLTV 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
+V ES N RA + DLSGQ LFIV VGA VYAVIEGPQIGWTS + +L TA VGCALF
Sbjct 181 GFVAESRNARAGQLDLSGQALFIVTVGAFVYAVIEGPQIGWTSPLILTLLMTAIVGCALF 240
Query 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYT 294
+WLE RS++PMMDLTLFRD+SYAL+I TICTVFFAVYGMLLLTTQFL NVRGYT
Sbjct 241 LWLEGRSADPMMDLTLFRDSSYALSIGTICTVFFAVYGMLLLTTQFLHNVRGYT 294
>gi|183983780|ref|YP_001852071.1| integral membrane transport protein [Mycobacterium marinum M]
gi|183177106|gb|ACC42216.1| conserved integral membrane transport protein [Mycobacterium
marinum M]
Length=524
Score = 411 bits (1056), Expect = 2e-112, Method: Compositional matrix adjust.
Identities = 229/522 (44%), Positives = 313/522 (60%), Gaps = 18/522 (3%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M R Q LT+ ATGLG+FM+F+D IVNVALP IQR F GE GLQW VA YSLGMA +M
Sbjct 1 MTRRQRLTVAATGLGIFMVFVDVNIVNVALPSIQRVFHTGEQGLQWAVAGYSLGMAAMLM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR + +G++LF S+ C L ++ + T AR QGLGA+ +SV SLAL+
Sbjct 61 SCALLGDRYGRRRGFFVGLALFVASSVVCVLPINLGMFTAARVIQGLGASFISVLSLALL 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S AFP+ + KARAI W AI +G + P LGGL+V+ GWRS+F VN+P+GA+VL LTL
Sbjct 121 SHAFPDQRMKARAIADWMAIGMVGAASAPALGGLMVETLGWRSVFAVNVPLGAIVLVLTL 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQT--------IVMLWT 232
V+ES + D GQL F+ + L Y +IE P+ SV + +LWT
Sbjct 181 IGVDESRDPDPTELDWVGQLTFVPGIAVLAYTIIEAPRFQQRSVIVLTSLLLIIVALLWT 240
Query 233 AAVGCALFVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRG 292
F+ ERR+ P++DL LF + Y + V +G L++ TQF QNVR
Sbjct 241 -------FIRHERRAPFPLIDLQLFTEPVYRSVLIVYFVVMSCFFGTLMVITQFFQNVRD 293
Query 293 YTPSVTGLMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSA 352
+P GLM+LP A + S L G V + G R+P++ L ++ GL++ + + A
Sbjct 294 LSPLHAGLMMLPVPAGFGMASLLAGAAVNKWGPRLPVVTCLAAMVTGLVLFVTAMGHVPA 353
Query 353 LVLVGLGLCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLA 412
L L+GL + G+G +TP+ + MT V RAGMA+G+++ QR++G G A LGS+LA
Sbjct 354 LALMGLTVFGAGAGGSVTPLLHLGMTKVDDHRAGMAAGLLNLQRSMGGIFGVAFLGSILA 413
Query 413 AWLSATLEPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAE 469
AWL ATL +E +PDPV R ++ + I+DSANP AH I PR I + + V+ A+
Sbjct 414 AWLGATLPDSMEDDLPDPVVRSIVVDTIVDSANPHAHAAFIGPRHRITSAQETNIVSAAD 473
Query 470 EDFIEGIRVALLVATATLAVVFLAGWRWFPRDVHTAGSDLSE 511
DF++GIR+AL A+ LA F+ G R FPR D E
Sbjct 474 SDFMQGIRIALGCASVLLAAAFVLGLRRFPRPDSDESPDPDE 515
>gi|118618990|ref|YP_907322.1| integral membrane transport protein [Mycobacterium ulcerans Agy99]
gi|118571100|gb|ABL05851.1| conserved integral membrane transport protein [Mycobacterium
ulcerans Agy99]
Length=554
Score = 404 bits (1039), Expect = 2e-110, Method: Compositional matrix adjust.
Identities = 228/524 (44%), Positives = 314/524 (60%), Gaps = 14/524 (2%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M R Q LT+ ATGLG+FM+F+D IVNVALP IQR F GE GLQW VA YSLGMA +M
Sbjct 31 MTRRQRLTVAATGLGIFMVFVDVNIVNVALPSIQRVFHTGEQGLQWAVAGYSLGMAAMLM 90
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR + +G++LF S+ C L ++ + T AR QGL A+ +SV SLAL+
Sbjct 91 SCALLGDRYGRRRGFFVGLALFVASSVVCVLPINLGMFTAARVIQGLDASFISVLSLALL 150
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S AFP+ + KARAI W AI +G + P LGGL+V+ GWRS+F V++P+GA+VL LTL
Sbjct 151 SHAFPDQRMKARAIADWMAIGMVGAASAPALGGLMVETLGWRSVFAVSVPLGAIVLVLTL 210
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVG-CAL 239
V+ES + D GQL F+ + L Y +IE P+ SV + L V
Sbjct 211 IGVDESRDPDPTELDWVGQLTFVPGIAVLAYTIIEAPRFQQRSVIVLTSLLLIIVALLRT 270
Query 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299
F+ ERR+ P++DL LF + Y + V +G L++ TQF QNVR +P G
Sbjct 271 FIRHERRAPFPLIDLQLFTEPVYRSVLIVYFVVMSCFFGTLMVITQFFQNVRDLSPLHAG 330
Query 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359
LM+LP A + S L G V + G R+P++ L ++ GL++ + + AL L+GL
Sbjct 331 LMMLPVPAGFGMASLLAGAAVNKWGPRLPVVTCLAAMVTGLVLFVTAMGHVPALALMGLT 390
Query 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419
+ G+G +TP+ + MT V RAGMA+G+++ QR++G G A LGS+LAAWL ATL
Sbjct 391 VFGAGAGGSVTPLLHLGMTKVDDHRAGMAAGLLNLQRSMGGIFGVAFLGSILAAWLGATL 450
Query 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476
+E +PDPV R ++ + I+DSANP AH I PR I + + V+ A+ DF++GI
Sbjct 451 PDSMEDDLPDPVVRSIVVDTIVDSANPHAHAAFIGPRHRITSAQETNIVSAADSDFMQGI 510
Query 477 RVALLVATATLAVVFLAGWRWF----------PRDVHTAGSDLS 510
R+AL A+ LA F+ G+R F P + AGSDL
Sbjct 511 RIALGCASVLLAAAFVLGFRRFACPDSDESPDPDESQLAGSDLD 554
>gi|253798462|ref|YP_003031463.1| membrane transporter [Mycobacterium tuberculosis KZN 1435]
gi|308372238|ref|ZP_07427935.2| conserved membrane transporter [Mycobacterium tuberculosis SUMu004]
gi|253319965|gb|ACT24568.1| conserved membrane transporter [Mycobacterium tuberculosis KZN
1435]
gi|308333916|gb|EFP22767.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu004]
gi|339298967|gb|AEJ51077.1| integral membrane transport protein [Mycobacterium tuberculosis
CCDC5180]
Length=538
Score = 387 bits (995), Expect = 2e-105, Method: Compositional matrix adjust.
Identities = 222/504 (45%), Positives = 301/504 (60%), Gaps = 4/504 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M
Sbjct 31 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 90
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+
Sbjct 91 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 150
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL
Sbjct 151 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 210
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCA-L 239
V+ES + + D GQL I AV + Y +IE P+ S + L AA L
Sbjct 211 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 270
Query 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299
FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G
Sbjct 271 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 330
Query 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359
LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL
Sbjct 331 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 390
Query 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419
+ G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L
Sbjct 391 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 450
Query 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476
+ +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI
Sbjct 451 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 510
Query 477 RVALLVATATLAVVFLAGWRWFPR 500
++AL A L F+ GW FPR
Sbjct 511 KLALGGAAVLLTGAFVLGWTRFPR 534
>gi|15609596|ref|NP_216975.1| integral membrane transport protein [Mycobacterium tuberculosis
H37Rv]
gi|121638342|ref|YP_978566.1| putative integral membrane transport protein [Mycobacterium bovis
BCG str. Pasteur 1173P2]
gi|148662294|ref|YP_001283817.1| putative transmembrane transport protein [Mycobacterium tuberculosis
H37Ra]
33 more sequence titles
Length=508
Score = 387 bits (995), Expect = 2e-105, Method: Compositional matrix adjust.
Identities = 222/504 (45%), Positives = 301/504 (60%), Gaps = 4/504 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M
Sbjct 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+
Sbjct 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL
Sbjct 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCA-L 239
V+ES + + D GQL I AV + Y +IE P+ S + L AA L
Sbjct 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240
Query 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299
FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G
Sbjct 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300
Query 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359
LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL
Sbjct 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360
Query 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419
+ G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L
Sbjct 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420
Query 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476
+ +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI
Sbjct 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480
Query 477 RVALLVATATLAVVFLAGWRWFPR 500
++AL A L F+ GW FPR
Sbjct 481 KLALGGAAVLLTGAFVLGWTRFPR 504
>gi|15841983|ref|NP_337020.1| drug transporter [Mycobacterium tuberculosis CDC1551]
gi|148823659|ref|YP_001288413.1| integral membrane transport protein [Mycobacterium tuberculosis
F11]
gi|289553750|ref|ZP_06442960.1| conserved membrane transporter [Mycobacterium tuberculosis KZN
605]
18 more sequence titles
Length=523
Score = 387 bits (995), Expect = 2e-105, Method: Compositional matrix adjust.
Identities = 222/504 (45%), Positives = 301/504 (60%), Gaps = 4/504 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M
Sbjct 16 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 75
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+
Sbjct 76 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 135
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL
Sbjct 136 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 195
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCA-L 239
V+ES + + D GQL I AV + Y +IE P+ S + L AA L
Sbjct 196 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 255
Query 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299
FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G
Sbjct 256 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 315
Query 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359
LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL
Sbjct 316 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 375
Query 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419
+ G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L
Sbjct 376 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 435
Query 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476
+ +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI
Sbjct 436 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 495
Query 477 RVALLVATATLAVVFLAGWRWFPR 500
++AL A L F+ GW FPR
Sbjct 496 KLALGGAAVLLTGAFVLGWTRFPR 519
>gi|254232593|ref|ZP_04925920.1| hypothetical protein TBCG_02400 [Mycobacterium tuberculosis C]
gi|254365235|ref|ZP_04981281.1| conserved integral membrane transport protein [Mycobacterium
tuberculosis str. Haarlem]
gi|308369723|ref|ZP_07418839.2| conserved membrane transporter [Mycobacterium tuberculosis SUMu002]
10 more sequence titles
Length=532
Score = 387 bits (994), Expect = 2e-105, Method: Compositional matrix adjust.
Identities = 222/504 (45%), Positives = 301/504 (60%), Gaps = 4/504 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M
Sbjct 25 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 84
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+
Sbjct 85 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 144
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL
Sbjct 145 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 204
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCA-L 239
V+ES + + D GQL I AV + Y +IE P+ S + L AA L
Sbjct 205 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 264
Query 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299
FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G
Sbjct 265 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 324
Query 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359
LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL
Sbjct 325 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 384
Query 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419
+ G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L
Sbjct 385 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 444
Query 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476
+ +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI
Sbjct 445 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 504
Query 477 RVALLVATATLAVVFLAGWRWFPR 500
++AL A L F+ GW FPR
Sbjct 505 KLALGGAAVLLTGAFVLGWTRFPR 528
>gi|307085143|ref|ZP_07494256.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu012]
gi|308365322|gb|EFP54173.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu012]
gi|323718965|gb|EGB28115.1| membrane transporter [Mycobacterium tuberculosis CDC1551A]
Length=601
Score = 387 bits (993), Expect = 3e-105, Method: Compositional matrix adjust.
Identities = 222/504 (45%), Positives = 301/504 (60%), Gaps = 4/504 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M
Sbjct 25 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 84
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+
Sbjct 85 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 144
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL
Sbjct 145 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 204
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCA-L 239
V+ES + + D GQL I AV + Y +IE P+ S + L AA L
Sbjct 205 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 264
Query 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299
FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G
Sbjct 265 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 324
Query 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359
LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL
Sbjct 325 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 384
Query 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419
+ G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L
Sbjct 385 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 444
Query 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476
+ +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI
Sbjct 445 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 504
Query 477 RVALLVATATLAVVFLAGWRWFPR 500
++AL A L F+ GW FPR
Sbjct 505 KLALGGAAVLLTGAFVLGWTRFPR 528
>gi|31793640|ref|NP_856133.1| integral membrane transport protein [Mycobacterium bovis AF2122/97]
gi|31619233|emb|CAD97347.1| PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN [Mycobacterium
bovis AF2122/97]
Length=508
Score = 385 bits (989), Expect = 1e-104, Method: Compositional matrix adjust.
Identities = 221/504 (44%), Positives = 301/504 (60%), Gaps = 4/504 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLG+A +M
Sbjct 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGIAAVLM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+
Sbjct 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL
Sbjct 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCA-L 239
V+ES + + D GQL I AV + Y +IE P+ S + L AA L
Sbjct 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240
Query 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299
FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G
Sbjct 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300
Query 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359
LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL
Sbjct 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360
Query 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419
+ G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L
Sbjct 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420
Query 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476
+ +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI
Sbjct 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480
Query 477 RVALLVATATLAVVFLAGWRWFPR 500
++AL A L F+ GW FPR
Sbjct 481 KLALGGAAVLLTGAFVLGWTRFPR 504
>gi|145594704|ref|YP_001159001.1| EmrB/QacA family drug resistance transporter [Salinispora tropica
CNB-440]
gi|145304041|gb|ABP54623.1| drug resistance transporter, EmrB/QacA subfamily [Salinispora
tropica CNB-440]
Length=524
Score = 385 bits (988), Expect = 1e-104, Method: Compositional matrix adjust.
Identities = 212/485 (44%), Positives = 306/485 (64%), Gaps = 6/485 (1%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
R Q T++A GLG+F+ D L+ NVALP IQ + +GE GLQW+VASYS+GMA+ IM
Sbjct 16 TRAQKWTIVAAGLGVFITLHDVLVANVALPRIQAFYGLGESGLQWIVASYSMGMAIAIMP 75
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
AAT+AD GRRR YL V +F + S+ G+ + AV+ ARG QG+ +A ++V++LALVS
Sbjct 76 AATVADRFGRRRLYLSAVVVFIVASVISGVTSTFAVMLVARGVQGVASAVITVSALALVS 135
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
A FP +++ A+G++ A+A +G GP LGG+L + WR +F+VN+P+ L + LTL
Sbjct 136 ATFPHKRQRFFALGLFAAVADVGLALGPPLGGILTETASWRLVFFVNVPVAVLAVGLTLR 195
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
YV ES R DL GQLLF++ VGA + VI+G +GW S + AVG A F+
Sbjct 196 YVAESRESTRRVVDLPGQLLFVITVGAFTFTVIDGHDLGWGSPTILATFVAFAVGLAAFI 255
Query 242 WLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLM 301
E RS +PMMDL LF +Y L I F VYG LL+ TQ+ QNVR Y+P GL+
Sbjct 256 VRELRSRSPMMDLRLFASRAYRLGNMAIFFGMFTVYGALLIVTQYFQNVRLYSPIEAGLL 315
Query 302 ILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGLC 361
ILP S A SP+ G + R GAR+P LAG +L++GL +++ S V++G L
Sbjct 316 ILPSSLASVAFSPVAGFIAARRGARLPALAGQVLLVVGLAVMVVGVAHSVVAVVLGFLLL 375
Query 362 GSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLEP 421
G+G++L + P+ +A+ +VP ERAGMASGI++ QR +GST G+AVLG++++ W+ L+
Sbjct 376 GAGLSLIIPPVQGLALNSVPVERAGMASGIVATQRGLGSTAGYAVLGTIVSVWVGIALDG 435
Query 422 HLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEH--RDPV----AIAEEDFIEG 475
L R +PD +R + E I+D NP A + P R ++H D V +A+ F+ G
Sbjct 436 DLSRTIPDRDERAAVVEQIVDDTNPNAFEAVVGPGRPVDHPESDQVTTIRTVADRTFVRG 495
Query 476 IRVAL 480
++++L
Sbjct 496 MQLSL 500
>gi|308232137|ref|ZP_07415066.2| conserved membrane transporter [Mycobacterium tuberculosis SUMu001]
gi|308214889|gb|EFO74288.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu001]
Length=574
Score = 384 bits (986), Expect = 2e-104, Method: Compositional matrix adjust.
Identities = 222/510 (44%), Positives = 302/510 (60%), Gaps = 4/510 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M
Sbjct 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+
Sbjct 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL
Sbjct 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCA-L 239
V+ES + + D GQL I AV + Y +IE P+ S + L AA L
Sbjct 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240
Query 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299
FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G
Sbjct 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300
Query 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359
LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL
Sbjct 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360
Query 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419
+ G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L
Sbjct 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420
Query 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476
+ +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI
Sbjct 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480
Query 477 RVALLVATATLAVVFLAGWRWFPRDVHTAG 506
++AL A L F+ GW FP +G
Sbjct 481 KLALGGAAVLLTGAFVLGWTRFPGPRQLSG 510
>gi|240169656|ref|ZP_04748315.1| integral membrane transport protein [Mycobacterium kansasii ATCC
12478]
Length=520
Score = 382 bits (981), Expect = 8e-104, Method: Compositional matrix adjust.
Identities = 218/507 (43%), Positives = 301/507 (60%), Gaps = 3/507 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M Q +T++ATGLG+FM+F+D IVNVALP IQ + GE GLQW VA YSLGMA +M
Sbjct 11 MTPRQRMTVVATGLGIFMVFVDINIVNVALPSIQAVYKTGEQGLQWAVAGYSLGMAAVLM 70
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR + IG+ +F S+ C + S+ +LT AR QG+GAA +SV SLAL+
Sbjct 71 SCALLGDRYGRRRGFFIGLGVFAAASMICAVPVSLGILTVARVVQGVGAAFISVLSLALL 130
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S AFP+ KARAI W AI IG + P LGG+LV++ GWRS+F VN+P+GA V LT
Sbjct 131 SHAFPDPGMKARAIAGWMAIGCIGAGSAPALGGILVEEMGWRSVFAVNVPLGAAVWLLTR 190
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
V ES + + D GQL+F AV L YA+IE P+ +++L A V F
Sbjct 191 LSVTESKDPDPTQLDWPGQLMFAPAVALLAYAIIEAPRADRQPGLMVILLSVAFVLLWFF 250
Query 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
V ERR+ P++DL LF Y A+ V +G L++ TQ QNVRG+TP GL
Sbjct 251 VQHERRAVFPLIDLQLFTHPVYRSALVVYFVVMSCYFGTLMVITQHFQNVRGFTPLQAGL 310
Query 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
++LP I S L G V G R+P+L L +++GL + + R +V+ GL L
Sbjct 311 LMLPVPVGFGIASLLAGRAVESWGPRLPVLICLAAMIVGLALFGIAIGRVMPVVVAGLAL 370
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
G+G C TP+ +AMT V RAGMA+G+++ QR++GS G A+LGS+LA WLS L
Sbjct 371 FGAGAGGCATPLLHIAMTEVDDHRAGMAAGLINLQRSLGSIFGVALLGSILAGWLSVALP 430
Query 421 PHLERAVPDPVQRHVLAEIIIDSANPRAH---VGGIVPRRHIEHRDPVAIAEEDFIEGIR 477
L+ + DP +R + ++D ANPRAH +G P + + V +A+++FI G++
Sbjct 431 ERLDDVISDPAERASVLSSVVDGANPRAHAAEIGPGHPTTSQQEQTIVRVADKEFIRGVQ 490
Query 478 VALLVATATLAVVFLAGWRWFPRDVHT 504
+A+ A L+ + G R FP T
Sbjct 491 LAVAGAAVLLSAALVLGVRRFPSGHRT 517
>gi|159037939|ref|YP_001537192.1| EmrB/QacA family drug resistance transporter [Salinispora arenicola
CNS-205]
gi|157916774|gb|ABV98201.1| drug resistance transporter, EmrB/QacA subfamily [Salinispora
arenicola CNS-205]
Length=524
Score = 366 bits (939), Expect = 6e-99, Method: Compositional matrix adjust.
Identities = 218/500 (44%), Positives = 308/500 (62%), Gaps = 10/500 (2%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
R Q T++A GLG+F+ D L+ NVALP IQ + + E GLQW+VA+YS+GMAV IM
Sbjct 16 TRAQKWTIVAAGLGMFITLHDVLVANVALPRIQSFYGLRESGLQWIVAAYSMGMAVAIMP 75
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
AAT+AD GRRR +L V +F+L S+A G AV+ AR QG+ +A ++V++LALVS
Sbjct 76 AATMADRFGRRRLFLTAVVVFSLASVAAGATSVFAVMLAARAVQGVASAVITVSALALVS 135
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
A FP +++ RA+G + A+A IG GP LGG L + WR +F+VN+P+ + + LTL
Sbjct 136 ATFPHKRQRFRALGFFVAVADIGLALGPPLGGFLAENASWRVVFFVNVPVAVVAVGLTLR 195
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
YV ES R DL GQLLF+V VGA +AVI+G +GW S + A G F+
Sbjct 196 YVAESRESTRRVVDLFGQLLFVVTVGAFTFAVIDGHDLGWGSPIILGAFTVFAAGLVAFI 255
Query 242 WLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLM 301
E RS +PMMDL LF Y L I I F VYG LL+ TQ+ QNVR Y+P GL+
Sbjct 256 VRELRSRSPMMDLRLFAHRPYRLGIMAIFFGMFTVYGTLLIVTQYFQNVRLYSPLEAGLL 315
Query 302 ILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLGLC 361
ILP S A ++SP+ G + R G R+P L G +++ GL++++ S V+VG L
Sbjct 316 ILPSSLAAVVLSPVAGFVAARRGPRLPALTGQFLVVSGLVVMVVGVSVSVPAVVVGFLLL 375
Query 362 GSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLEP 421
G+G++L + P+ +A+ +VP ERAGMASGI++ QR +GST G+AVLG ++A W+ L+
Sbjct 376 GAGLSLIIAPVQGLALNSVPVERAGMASGIVATQRGLGSTAGYAVLGMIVAVWVGIALDS 435
Query 422 HLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHIEHRDP------VAIAEEDFIEG 475
L R +PD +R + I+D+ NP A + P R I H DP A+A+ F+ G
Sbjct 436 DLSRTIPDRDERATVVARIVDNTNPNAFEAVVGPGRPIAHPDPDQVTKIRAVADRTFVRG 495
Query 476 IRVAL----LVATATLAVVF 491
++++L LVA L ++F
Sbjct 496 MQLSLGFAALVALIILVILF 515
>gi|294994433|ref|ZP_06800124.1| membrane transporter [Mycobacterium tuberculosis 210]
Length=508
Score = 332 bits (850), Expect = 1e-88, Method: Compositional matrix adjust.
Identities = 202/504 (41%), Positives = 280/504 (56%), Gaps = 4/504 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
M Q LT++A G + + P +R F VA YSLGMA +M
Sbjct 1 MTPRQRLTVLARGWASSWVSWTSTSSMSHCPASKRCFTRANKVCSGPVAGYSLGMAAVLM 60
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
S A L D GRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+
Sbjct 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL
Sbjct 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCA-L 239
V+ES + + D GQL I AV + Y +IE P+ S + L AA L
Sbjct 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240
Query 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299
FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G
Sbjct 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300
Query 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359
LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL
Sbjct 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360
Query 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419
+ G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L
Sbjct 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420
Query 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476
+ +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI
Sbjct 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480
Query 477 RVALLVATATLAVVFLAGWRWFPR 500
++AL A L F+ GW FPR
Sbjct 481 KLALGGAAVLLTGAFVLGWTRFPR 504
>gi|226304701|ref|YP_002764659.1| drug resistance efflux protein [Rhodococcus erythropolis PR4]
gi|226183816|dbj|BAH31920.1| putative drug resistance efflux protein [Rhodococcus erythropolis
PR4]
Length=472
Score = 289 bits (740), Expect = 8e-76, Method: Compositional matrix adjust.
Identities = 168/406 (42%), Positives = 244/406 (61%), Gaps = 1/406 (0%)
Query 16 LFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLADLDGRRRWY 75
LF++ LD IVNVALP I F VG GL+W+V +Y+L +A ++S+ LAD GRRR +
Sbjct 35 LFVVGLDTTIVNVALPAIGEGFGVGTVGLEWIVNAYTLVLASLLISSGALADRFGRRRIF 94
Query 76 LIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPEAKEKARAIG 135
IG+ +F + SI C LAPS+ VL AR AQG+G + +S +LA+V + KE+A+AIG
Sbjct 95 QIGLVVFGVASIVCALAPSVGVLIAARIAQGVGGSMLSPVALAIVVNVMTDPKERAKAIG 154
Query 136 IWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARRFD 195
+W A+ + GP +GG+L++ +GWRS+F++N+P+ A+VL LT +V +S E+ RR D
Sbjct 155 VWAAVFGLSMAAGPIVGGVLIESFGWRSVFWINVPVIAVVLMLTAVFVPQSRAEQPRRLD 214
Query 196 LSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERRSSNPMMDLT 255
L GQ+L +V VG V +IEGP+IGW + I A A FV +E R S P+MD +
Sbjct 215 LPGQVLLMVVVGGSVALLIEGPRIGWLASGAIAGYVAVAAALAAFVRVESRKSEPLMDPS 274
Query 256 LFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFSAAVAIVSPL 315
LFR + A+ VF A+ LLL T +LQ R TP+ G M LP + A I +PL
Sbjct 275 LFRHRPFTAAVLGAIVVFVALNATLLLGTFYLQQAREMTPAAAGAMTLPMAVAATICAPL 334
Query 316 VGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGLCGSGVALCLTPITT 374
G LVGR GAR+P+L AG + GL ++ ++ +LV G G PIT
Sbjct 335 SGILVGRFGARLPLLIAGSFTALGGLCLVSLDNSTGTSTLLVAYLFLGIGFGFSNAPITN 394
Query 375 VAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
A+ +P +AG+A GI S+ R G+ +G A+ G ++A + ++
Sbjct 395 TAVNGLPRSQAGLAGGITSSARQFGAALGVALAGGMIAGSAQSDID 440
>gi|229490123|ref|ZP_04383971.1| efflux membrane protein [Rhodococcus erythropolis SK121]
gi|229322999|gb|EEN88772.1| efflux membrane protein [Rhodococcus erythropolis SK121]
Length=467
Score = 289 bits (739), Expect = 1e-75, Method: Compositional matrix adjust.
Identities = 161/397 (41%), Positives = 239/397 (61%), Gaps = 1/397 (0%)
Query 16 LFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLADLDGRRRWY 75
LF++ LD IVNVALP I F VG GL+WVV +Y+L +A ++S+ +AD GRRR +
Sbjct 30 LFVVGLDTTIVNVALPTIGEGFRVGTRGLEWVVNAYTLVLASLLISSGAVADRFGRRRVF 89
Query 76 LIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPEAKEKARAIG 135
IG+ +F + SIAC LAPS+ VL AR QG+G + +S +LA+V + KE+A+AIG
Sbjct 90 QIGLVVFGVASIACALAPSVEVLIAARIVQGVGGSMLSPVALAIVVNVMTDPKERAKAIG 149
Query 136 IWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARRFD 195
+W A+ + GP +GG+L++ +GWRS+F++N+P+ VL LT +V ES +++RR D
Sbjct 150 VWAAVFGLSMAAGPIVGGVLIESFGWRSVFWINVPVILAVLVLTAVFVPESRAQQSRRLD 209
Query 196 LSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERRSSNPMMDLT 255
L GQLL ++ VG V +IEGP+IGW S A A F+ +E R P+MDL
Sbjct 210 LPGQLLLVILVGGAVALLIEGPRIGWFSAAATAGYVVVAAALAAFIRVESRKREPLMDLA 269
Query 256 LFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFSAAVAIVSPL 315
LFR ++ A+ VF A+ LLL T +LQ+ RG +P++ G + LP + A + +PL
Sbjct 270 LFRRRPFSSAVIGAVVVFVALNATLLLGTFYLQHSRGMSPALAGAITLPMAVAATVCAPL 329
Query 316 VGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGLCGSGVALCLTPITT 374
G LVGR G R P+L AG + GL ++ + + ++L G G PIT
Sbjct 330 SGILVGRFGPRRPLLIAGSFTTLGGLCLVSLDNNTAIPMLLAAYLFLGIGFGFSNAPITN 389
Query 375 VAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVL 411
A+ +P +AG+A GI S+ R G+ +G A+ G ++
Sbjct 390 TAVNGLPRSQAGLAGGITSSARQFGAALGVALAGGII 426
>gi|312200663|ref|YP_004020724.1| drug resistance transporter EmrB/QacA subfamily [Frankia sp.
EuI1c]
gi|311231999|gb|ADP84854.1| drug resistance transporter, EmrB/QacA subfamily [Frankia sp.
EuI1c]
Length=480
Score = 287 bits (734), Expect = 4e-75, Method: Compositional matrix adjust.
Identities = 163/418 (39%), Positives = 238/418 (57%), Gaps = 5/418 (1%)
Query 16 LFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLADLDGRRRWY 75
LF++ LD I+NV LP ++ + GLQW + +Y L +A ++ + ++ D GR+R +
Sbjct 9 LFIVGLDTTILNVGLPSLKHDLHAPDSGLQWTIDAYGLVIASLLLFSGSMGDRFGRKRVF 68
Query 76 LIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPEAKEKARAIG 135
G+ LF+ GS+ C LAP + L R Q +G + ++ ++A+++ F E +E+ARAIG
Sbjct 69 RTGLILFSAGSLLCSLAPGLGWLIAFRMIQAVGGSMLNPVAMAIITNTFTERRERARAIG 128
Query 136 IWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARRFD 195
+W A+ + GP LGG+LVD GWRSIF++N+P+G + LT +V ES RARRFD
Sbjct 129 VWGAVIGLSMALGPVLGGVLVDGIGWRSIFWINVPIGLAAMVLTGLFVPESKAPRARRFD 188
Query 196 LSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERRSSNPMMDLT 255
+GQLL +G L Y +IE P GW S QTIVM AAV V +E R ++D+
Sbjct 189 PAGQLLVAATLGTLTYGIIEAPSAGWASTQTIVMFVIAAVALVGLVIVETRREEALLDMR 248
Query 256 LFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFSAAVAIVSPL 315
FR ++ A F A+ G L L T +LQNVRGY+ GL+ LP +A AI+ P+
Sbjct 249 FFRSVPFSGATGIAVCAFAALGGFLFLNTLYLQNVRGYSALHAGLLTLPMAAFAAIMPPI 308
Query 316 VGHLVGRIGARVP-ILAGLCMLMLGLLMLIFSEHRSSALVLVGLGLCGSGVALCLTPITT 374
G LVG G R I+AG+ + GLL+ H S L++ L G G + PIT
Sbjct 309 SGRLVGSRGPRPSLIVAGIALPASGLLLTFLGPHTSLVLLISAYVLFGIGFGMVNAPITN 368
Query 375 VAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLEPHLERAVPDPVQ 432
A++ +P +AG+A+ + S R IGS +G A+LGSV A + + RA DP
Sbjct 369 TAVSGMPVTQAGVAAAVASTSRQIGSALGVAILGSVAA----HSAAGQVGRAAIDPTS 422
>gi|298251605|ref|ZP_06975408.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter
racemifer DSM 44963]
gi|297546197|gb|EFH80065.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter
racemifer DSM 44963]
Length=529
Score = 285 bits (729), Expect = 2e-74, Method: Compositional matrix adjust.
Identities = 174/479 (37%), Positives = 265/479 (56%), Gaps = 8/479 (1%)
Query 5 QLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAAT 64
+L LI T +G FM+ LD IVNVALP IQ F LQW+V +Y+L A +++A +
Sbjct 9 KLAILIITCVGFFMVLLDTSIVNVALPTIQTDFHASLTDLQWMVDAYTLPFAALLLTAGS 68
Query 65 LADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAF 124
L D GR+R +LIG+ FTLGS C LAP++ +L R QG G AA+S SL+L+ AAF
Sbjct 69 LGDRFGRKRLFLIGLIGFTLGSALCALAPNLQLLIAGRALQGAGGAALSPGSLSLLVAAF 128
Query 125 PEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVE 184
+ KE+ +A+GIW+ I+ + GP +GG+L+ W +IF+VNLP+G LV L +
Sbjct 129 TDHKERTQALGIWSGISGLALAAGPVVGGVLIRVSNWPAIFFVNLPIGTLVFILGWRILA 188
Query 185 ESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLE 244
ES N ARR DL GQ+L I + +L YA+IEG GWTS + + +AA F+ +E
Sbjct 189 ESRNPHARRLDLPGQVLAIAGLASLTYALIEGESAGWTSPLILSLFASAAAFLIAFLVVE 248
Query 245 RRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILP 304
R P++ L LF+ ++ A A V FA+ + TQ+ Q+V+GY+ GL LP
Sbjct 249 ARVREPLLPLQLFKSVVFSTANAAAAVVGFALLSTVFFVTQYFQSVQGYSALDAGLRTLP 308
Query 305 FSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLI-FSEHRSSALVLVGLGLCGS 363
S + + +P+ G + R G RVPI G + + LL+LI S A + G+ G
Sbjct 309 SSMGIFLTAPVAGQVAARFGPRVPITLGALLSGVALLLLIRLDPTTSYANIWWNQGMYGI 368
Query 364 GVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLEPHL 423
G L L+P+T ++ +P RAG+ S +++ R IGS G A+LG+++ L L
Sbjct 369 GFGLMLSPLTAAGLSTIPQHRAGLGSAVLNTSRQIGSVFGIALLGALVEQQFINNLFSKL 428
Query 424 ER-AVPDPVQRHVLAEIIIDSAN-PRAHVGGIVP-RRHIEHRDPVAIAEEDFIEGIRVA 479
+P + + ++A I A + G +P H+ H+ + + F + + ++
Sbjct 429 SNLGIPGSISQKMVATIASAGAEGGQVQFSGSLPVASHVLHQ----VINQAFTDSLHIS 483
>gi|254382912|ref|ZP_04998268.1| efflux membrane protein [Streptomyces sp. Mg1]
gi|194341813|gb|EDX22779.1| efflux membrane protein [Streptomyces sp. Mg1]
Length=483
Score = 282 bits (722), Expect = 9e-74, Method: Compositional matrix adjust.
Identities = 162/416 (39%), Positives = 247/416 (60%), Gaps = 7/416 (1%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
+R +LL L + L ++ LD ++NVALP ++R G+QW + +Y+L +A ++
Sbjct 6 HRRRLLVLAICCMSLLIVSLDNTVLNVALPSMRRELHASVAGMQWTIDAYTLVLASLLIL 65
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
+ AD GRR+ + IG+++F LGS+ C +APS+ L R Q +G A ++ ++++++
Sbjct 66 MGSTADRIGRRKVFTIGLTVFVLGSLLCSVAPSLGWLIVFRTVQAIGGAMLNPVAMSIIT 125
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
F E E+ARAIGIW A+A I GP +GG+L D GWRSIF++N+P+G L LTL
Sbjct 126 NTFTEPAERARAIGIWGAVAGISMAAGPLIGGVLTDSVGWRSIFWINVPVGLFALALTLR 185
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
++ ES ER RR D GQLL + +G++ Y +IEGP GW+S ++L AV A V
Sbjct 186 WIPESRAERPRRPDPVGQLLVMALLGSVTYGIIEGPAAGWSSG---LILGCGAVAVASLV 242
Query 242 WL---ERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVT 298
L E+R + P++D FR ++ A + F + G L L T +LQ+VRG
Sbjct 243 GLVAYEQRRTEPLIDPRFFRSVPFSGATVMAVSAFSGMAGFLFLNTLYLQDVRGLDALDA 302
Query 299 GLMILPFSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVG 357
GL +LP +A + +P+ G LV G R+P+L AG+ M + GLL FS S++L+ G
Sbjct 303 GLYMLPMAACTILAAPVAGRLVAARGPRLPLLIAGVAMAVSGLLFAAFSAETSTSLMFTG 362
Query 358 LGLCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAA 413
L G G + PIT A++ +P +AG+A+ + S R GST+G AV+G+VLAA
Sbjct 363 YVLFGLGFGMVNAPITNTAVSGMPRSQAGVAAAVASTSRQTGSTLGVAVIGAVLAA 418
>gi|256391255|ref|YP_003112819.1| drug resistance transporter EmrB/QacA subfamily [Catenulispora
acidiphila DSM 44928]
gi|256357481|gb|ACU70978.1| drug resistance transporter, EmrB/QacA subfamily [Catenulispora
acidiphila DSM 44928]
Length=480
Score = 282 bits (722), Expect = 9e-74, Method: Compositional matrix adjust.
Identities = 167/404 (42%), Positives = 246/404 (61%), Gaps = 1/404 (0%)
Query 7 LTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLA 66
+TL+AT L LF+ +D VN+ALP I+ + G GLQWVV +Y++ A +++ TL
Sbjct 27 VTLLATCLALFLGQVDTTAVNLALPAIRHDLSGGISGLQWVVDAYNVTFAALLLTGGTLG 86
Query 67 DLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPE 126
D GRRR + GV++F LGS C LAP + VL R QG+G+ + SLA+++ AFP
Sbjct 87 DRFGRRRLFRTGVAVFVLGSTVCALAPGLPVLLAGRVTQGVGSGMMLPQSLAILATAFPG 146
Query 127 AKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEES 186
+E+ +A+ W+ +A G GPTLGGL V GW+SIF+VN+P+G L LTL +V ES
Sbjct 147 RRERNKAMAAWSIVAGSGLAVGPTLGGLAVQTLGWQSIFWVNVPIGIAALVLTLRHVPES 206
Query 187 CNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERR 246
N RAR D GQ+L I ++G L + ++G ++GWTS T+ + VG A FV +ERR
Sbjct 207 RNPRARTLDPLGQVLAIASLGLLTFVAVQGRELGWTSPATLACIAGCVVGPAAFVAVERR 266
Query 247 SSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFS 306
S+PM+ L L R +A+ + F +YG+ LLT+ Q RG + G+ +LP +
Sbjct 267 RSDPMLPLDLLRRGQLPVAVIVAACMTFGMYGLFLLTSLMFQQERGASALGAGVAMLPLA 326
Query 307 AAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVL-VGLGLCGSGV 365
A ++SPL G LV R G R+P+ AG+ + G+L+ + ++ LVL + + G G+
Sbjct 327 VAATVLSPLTGRLVTRYGPRLPMTAGMTAMGTGVLIFAVAGADANLLVLEIAFTVIGIGL 386
Query 366 ALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGS 409
AL P+ VA++AV +E AG+ASGI + R G+T+G AV GS
Sbjct 387 ALNTGPVVGVAVSAVASELAGLASGIANLARMFGATLGVAVQGS 430
>gi|288918903|ref|ZP_06413246.1| drug resistance transporter, EmrB/QacA subfamily [Frankia sp.
EUN1f]
gi|288349655|gb|EFC83889.1| drug resistance transporter, EmrB/QacA subfamily [Frankia sp.
EUN1f]
Length=539
Score = 279 bits (714), Expect = 7e-73, Method: Compositional matrix adjust.
Identities = 160/396 (41%), Positives = 240/396 (61%), Gaps = 1/396 (0%)
Query 14 LGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLADLDGRRR 73
+ L ++ LD IVN+ALP ++R F GLQW + SY++ +A +M A ++ D GRRR
Sbjct 20 MSLLIVGLDNTIVNIALPSLRRDFDASPAGLQWSIDSYTIVLASLLMLAGSMGDRLGRRR 79
Query 74 WYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPEAKEKARA 133
+ G++LFTLGS+ C +APS+ L R Q +G + ++ ++++++ F + +E+ARA
Sbjct 80 IFQTGLALFTLGSLLCSIAPSLHWLVAFRMVQAVGGSMLNPVAMSIITNTFTDPRERARA 139
Query 134 IGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARR 193
IG+W A+ I GP LGG+LV+ GWRSIF++N+P+G + L L YV ES R RR
Sbjct 140 IGVWGAVIGISMALGPVLGGVLVEWVGWRSIFWINIPIGLIALTLAQLYVPESRAARPRR 199
Query 194 FDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERRSSNPMMD 253
D GQ+L I + AL Y++I P+ GWTS +T+ +L A V AL V E R P++D
Sbjct 200 LDAVGQVLVIFILAALTYSLIAAPEAGWTSARTLGLLAGAGVAVALLVRYESRREEPLLD 259
Query 254 LTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFSAAVAIVS 313
+ LFR S++ A T A+ G LLL T +LQ+VRGY P GL+ LP +A + I +
Sbjct 260 VRLFRVASFSGATLTAVCALGALGGSLLLNTIYLQDVRGYEPLHAGLVTLPMAAGIIIGA 319
Query 314 PLVGHLVGRIGARVPILAGLCMLMLG-LLMLIFSEHRSSALVLVGLGLCGSGVALCLTPI 372
PL G V R G R +LA L LG L M+ F S+ +L+ + G+G L PI
Sbjct 320 PLSGRAVARFGPRPSLLAAGVGLTLGSLAMVGFDAGSSTGQLLIAYVVFGAGFGLVNAPI 379
Query 373 TTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLG 408
T A++ +P E+AG+A+ + S R +G ++G A++G
Sbjct 380 TNTAVSGMPVEQAGVAAAVASTSRQVGQSLGVALVG 415
>gi|297194492|ref|ZP_06911890.1| efflux membrane protein [Streptomyces pristinaespiralis ATCC
25486]
gi|197718698|gb|EDY62606.1| efflux membrane protein [Streptomyces pristinaespiralis ATCC
25486]
Length=490
Score = 276 bits (707), Expect = 6e-72, Method: Compositional matrix adjust.
Identities = 168/418 (41%), Positives = 247/418 (60%), Gaps = 1/418 (0%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
+R ++L L + L ++ LD I+NVALP ++R G+QWV+ +Y+L +A +M
Sbjct 6 HRHRILVLAICCMSLLIVSLDNTILNVALPSLRRELDASVAGMQWVIDAYTLVLASLLML 65
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
A ++AD GRR+ ++IG+ LFTLGS+ C LA ++ L R Q +G + ++ ++++++
Sbjct 66 AGSVADRVGRRKIFMIGLVLFTLGSLLCSLAQNLGSLVAFRMVQAVGGSMLNPVAMSIIT 125
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
F + +E+ARAIG+W + I GP +GGLLVD GWRSIF+VNLP+G L LT
Sbjct 126 NTFTDPRERARAIGVWGGVVGISMAAGPLVGGLLVDGVGWRSIFWVNLPVGLAALLLTWR 185
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
YV ES RARRFD GQLL I +G+L YA+IE P GWTS + AA+ A +
Sbjct 186 YVPESRAPRARRFDPVGQLLVITLLGSLTYAIIEAPVAGWTSPLILTFAVVAALALAGLL 245
Query 242 WLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLM 301
E R + P++DL F ++ A + F A+ G L + T +LQ+VRG + GL
Sbjct 246 RHEPRRAEPLIDLRFFHSLPFSGATVIAVSAFAALGGFLFVNTLYLQDVRGLSALNAGLY 305
Query 302 ILPFSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
+LP + + +PL G LV G R +L AG M G+L F S+AL+ G L
Sbjct 306 MLPMAGLTLVCAPLSGRLVAAYGPRPSLLAAGTAMTASGVLFAAFEAETSTALLFTGYVL 365
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSAT 418
G G L PIT A++ +P +AG+A+ + S R IG T+G AV+G+VLAA +SA+
Sbjct 366 FGLGFGLVNAPITNTAVSGMPRAQAGVAAAVASTSRQIGQTLGVAVIGAVLAAGVSAS 423
>gi|111220069|ref|YP_710863.1| putative efflux membrane protein [Frankia alni ACN14a]
gi|111147601|emb|CAJ59256.1| Putative efflux membrane protein (partial match) [Frankia alni
ACN14a]
Length=599
Score = 273 bits (698), Expect = 5e-71, Method: Compositional matrix adjust.
Identities = 162/415 (40%), Positives = 240/415 (58%), Gaps = 11/415 (2%)
Query 5 QLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAAT 64
+LL L + LF++ LD IVNVALP ++R GLQW + +Y+L +A +M +
Sbjct 9 RLLVLAICCMSLFIVGLDNTIVNVALPSLRRDLHASASGLQWTIDAYTLVLASLLMLGGS 68
Query 65 LADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAF 124
D GRRR + G+ LFTLGS+ C LAPS+ L R Q +G + ++ +++++S F
Sbjct 69 TGDRLGRRRVFQTGLVLFTLGSLLCSLAPSLTWLIVFRMVQAVGGSMLNPVAMSIISNTF 128
Query 125 PEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVE 184
+++E+ARAIG+W A+ + GP LGG LV+ WR+IF+VN+P+G L L +V
Sbjct 129 TDSRERARAIGVWGAVIGVSMALGPVLGGTLVESVSWRAIFWVNVPVGVAALVLAGLFVP 188
Query 185 ESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLE 244
ES RARRFD GQ L IV + +L Y +IE P GW + +T+ + +A+ A+ V E
Sbjct 189 ESRAARARRFDPVGQALVIVILASLTYGIIEAPSAGWLAARTLALFAVSALAAAVLVRYE 248
Query 245 RRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILP 304
R + P++D+ FR +A A F A+ G L L T +LQ VRGY+P + G+ LP
Sbjct 249 GRRAQPLLDVRFFRAAPFAGATGIAVFAFAALAGFLFLNTLYLQEVRGYSPLLAGITTLP 308
Query 305 FSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRS-----SALVLVGL 358
+ + +P+ G LV GAR P+L AG+ M +++ S SA VLVGL
Sbjct 309 MAGMTVVSAPIAGRLVASRGARTPLLIAGVTMTAGSVMLTALGVSTSILWLVSAYVLVGL 368
Query 359 GLCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAA 413
G + PIT A+T +P +AG+A+GI S R +G ++G AV+GS+ AA
Sbjct 369 GF-----GMVNAPITNTAVTGMPQSQAGVAAGIASTSRQVGQSLGVAVIGSLAAA 418
>gi|209515436|ref|ZP_03264302.1| drug resistance transporter, EmrB/QacA subfamily [Burkholderia
sp. H160]
gi|209504156|gb|EEA04146.1| drug resistance transporter, EmrB/QacA subfamily [Burkholderia
sp. H160]
Length=464
Score = 273 bits (697), Expect = 8e-71, Method: Compositional matrix adjust.
Identities = 162/397 (41%), Positives = 240/397 (61%), Gaps = 1/397 (0%)
Query 3 RTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSA 62
R+ L L+AT LG +I LD +VNVAL ++ S A+ L+WVV +Y+L A ++SA
Sbjct 10 RSSRLALLATSLGFVIICLDVTVVNVALARMRDSLALDSTALEWVVNAYTLAFASLLLSA 69
Query 63 ATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSA 122
LAD G RR +L G +FT S+ CGL+ A+L AR QG+GAA +SLAL++A
Sbjct 70 GALADRFGARRVFLAGFVVFTCASVGCGLSGGAAMLIVARVLQGVGAALCVPSSLALLAA 129
Query 123 AFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCY 182
AFP+ K +A+A+ +W A++ GP +GGLLVD++GW +IF +N+P+G ++LT+ +
Sbjct 130 AFPDPKARAKAVSVWAGTAALALGAGPLVGGLLVDRFGWPAIFLINVPIGVAGIWLTVAH 189
Query 183 VEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVW 242
++ +RR DL+GQ L ++A+ L YAV+E + GWTSV ++ L AAV LFV
Sbjct 190 APDTLGHASRRIDLAGQTLAVIALVGLTYAVVECGRPGWTSVTVMMGLAVAAVAGGLFVV 249
Query 243 LERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMI 302
+E R + P++ L LFR+ + ++ T ++ F YG++ + F QN R TP TGL
Sbjct 250 VEARHAQPLLPLALFRNAAVNVSSLTGLSLNFGYYGLMFAMSLFFQNARHDTPLETGLAF 309
Query 303 LPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSAL-VLVGLGLC 361
LP +A VA+ + G L R G R+P++ G + LG L L+F SSAL V + L
Sbjct 310 LPMTAVVAVANIASGSLTARFGYRLPMVVGQALAALGYLSLVFVRVDSSALAVSLPLLTV 369
Query 362 GSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAI 398
G GVAL + I T +T V G+ASG+++ R I
Sbjct 370 GVGVALAVPSINTAVLTHVDPSYLGVASGVLNTARQI 406
>gi|329934688|ref|ZP_08284729.1| efflux membrane protein [Streptomyces griseoaurantiacus M045]
gi|329305510|gb|EGG49366.1| efflux membrane protein [Streptomyces griseoaurantiacus M045]
Length=484
Score = 272 bits (696), Expect = 9e-71, Method: Compositional matrix adjust.
Identities = 161/424 (38%), Positives = 247/424 (59%), Gaps = 5/424 (1%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
+R ++L L + L ++ LD ++NVALP +Q GLQW + +Y+L +A +M
Sbjct 6 HRRRMLVLAICCMSLLIVGLDNTVLNVALPSLQEDLDTSTSGLQWAIDAYTLVLASLLML 65
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
A + AD GR+R +L G+++FT GS C LAP++ L R Q +G + ++ ++++++
Sbjct 66 AGSTADRIGRKRVFLTGLAVFTAGSALCSLAPNLQTLVVFRMVQAVGGSMLNPVAMSIIT 125
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
F + +E+ARAIG W A+ + GP +GGLLV+ GWRSIF++N+P+G L LTL
Sbjct 126 NTFTDPRERARAIGAWGAVMGVSMAAGPLVGGLLVESVGWRSIFWLNIPVGLAALLLTLR 185
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
+V ES + RR D GQL+ I GAL YA+IE P G+ +V +L AA+ A +
Sbjct 186 FVPESRAPKPRRLDPLGQLMVIALFGALTYAIIEVPDAGFRAVLPYAVLAAAAL--AGLL 243
Query 242 WLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLM 301
E R + P++DL FR ++ A + F ++ G L LTT +LQNVRG GL
Sbjct 244 LYEPRRAEPLIDLRFFRSAPFSGATVIAISAFASLGGFLFLTTLYLQNVRGLDALHAGLW 303
Query 302 ILPFSAAVAIVSPLVGHLVGRIGARVP-ILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
+LP + + +PL G LVG G R+P ILAG M L +F S+ + +G L
Sbjct 304 MLPMAVPTCLCAPLSGRLVGSRGPRLPLILAGCAMTACCALFAVFEAETSNVALFLGYVL 363
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLE 420
G G +PIT A++ +P E+AG+A+ + S R +G T+G AV+G+VLA+ + A+
Sbjct 364 FGIGFGFVNSPITNTAVSGMPKEQAGVAAAVASTSRQLGQTLGVAVVGAVLASGVGAS-- 421
Query 421 PHLE 424
P+ E
Sbjct 422 PYRE 425
>gi|29832191|ref|NP_826825.1| efflux membrane protein [Streptomyces avermitilis MA-4680]
gi|29609309|dbj|BAC73360.1| putative efflux membrane protein [Streptomyces avermitilis MA-4680]
Length=481
Score = 272 bits (696), Expect = 1e-70, Method: Compositional matrix adjust.
Identities = 163/412 (40%), Positives = 239/412 (59%), Gaps = 3/412 (0%)
Query 3 RTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSA 62
R +LL L L L ++ LD ++NVALP +Q+ GLQW + +Y+L +A +M A
Sbjct 7 RRRLLVLAICCLSLLIVSLDNTVLNVALPSMQKELHASVAGLQWTIDAYTLVLASLLMLA 66
Query 63 ATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSA 122
+ AD GRRR + G+ LFT+GS+ C LAP++ L R Q +G + ++ ++++++
Sbjct 67 GSTADRIGRRRVFRTGLVLFTIGSVLCSLAPNLESLVAFRMVQAVGGSMLNPVAMSIITN 126
Query 123 AFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCY 182
F E +E+ARAIG+W + I GP +GGLLVD GWRSIF++NLP+G + L LT Y
Sbjct 127 TFTEPRERARAIGVWGGVVGISMAAGPIVGGLLVDSVGWRSIFWINLPVGLVALLLTWRY 186
Query 183 VEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVW 242
V ES +ARR D GQLL I +G+L YA+IE P G + + + TA +W
Sbjct 187 VPESRAPKARRPDPVGQLLVIALLGSLTYAIIEAPSSG--AAEILAFGGTALAALIALLW 244
Query 243 LERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMI 302
E R + P++DL FR ++ A + F A+ G L L+T +LQNVRG + GL +
Sbjct 245 YEPRRAEPLIDLRFFRSVPFSGATVVAISAFAALSGFLFLSTLYLQNVRGLSALHAGLWM 304
Query 303 LPFSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGLC 361
LP + + +PL G LVG G R +L AG+ M G+L F S +++G L
Sbjct 305 LPMAVMCFVCAPLSGRLVGSRGPRFSLLTAGIAMTASGVLFAAFEAETSDVTLVIGYVLF 364
Query 362 GSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAA 413
G G PIT A++ +P +AG+A+ I S R IG T+G AV+G+VLA+
Sbjct 365 GVGFGFVNAPITNTAVSGMPRAQAGVAAAIASTSRQIGGTLGVAVVGAVLAS 416
>gi|297199530|ref|ZP_06916927.1| efflux protein [Streptomyces sviceus ATCC 29083]
gi|297147422|gb|EDY56955.2| efflux protein [Streptomyces sviceus ATCC 29083]
Length=481
Score = 271 bits (692), Expect = 3e-70, Method: Compositional matrix adjust.
Identities = 165/429 (39%), Positives = 249/429 (59%), Gaps = 5/429 (1%)
Query 3 RTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSA 62
R ++L L + L ++ LD +NVALP +QR GLQW + +Y+L +A +M A
Sbjct 7 RRRMLVLAICCMSLLIVSLDTTALNVALPAMQRGLDASTAGLQWTIDAYTLVLASLLMLA 66
Query 63 ATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSA 122
+ AD GR+R ++ G+ +FT+GS C AP++ L R Q +G + ++ ++++++
Sbjct 67 GSTADRIGRKRVFMAGLIVFTIGSALCSAAPNLEALIAFRMVQAVGGSMLNPVAMSIITN 126
Query 123 AFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCY 182
F + +E+ARAIG+W A+ I GP +GG+LVD GWRSIF+VNLP+G L LTL Y
Sbjct 127 TFTDPRERARAIGVWGAVVGISMAAGPLVGGVLVDSVGWRSIFWVNLPVGLAALLLTLRY 186
Query 183 VEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVW 242
V ES RARR D GQLL I G+L YA+IE P G++ V ++ A + A +W
Sbjct 187 VPESRAPRARRPDPVGQLLVIALFGSLTYAIIEAPASGFSYVLPFAVV--AVLALAGLLW 244
Query 243 LERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMI 302
E R P++DL FR ++ A + F + G L L+T +LQNVRG GL +
Sbjct 245 YEPRRDEPLIDLRFFRSAPFSGATVIAISAFAGLGGFLFLSTLYLQNVRGLDALHAGLWM 304
Query 303 LPFSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGLC 361
LP + + + +PL G LVG G R+P++ AG+ + G+L F S +L+G L
Sbjct 305 LPMAVPMFLCAPLAGRLVGSRGPRLPLIAAGVMITASGVLFAAFDAETSDRTLLLGYVLF 364
Query 362 GSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWL--SATL 419
G G L PIT A++ +P +AG+A+ + S R +G T+G AV+G+VLA+ + S+
Sbjct 365 GIGFGLVNAPITNTAVSGMPRAQAGVAAAVASTSRQLGQTLGVAVVGAVLASGVGSSSYK 424
Query 420 EPHLERAVP 428
E + AVP
Sbjct 425 EKFVSAAVP 433
>gi|302560756|ref|ZP_07313098.1| drug resistance transporter, EmrB/QacA family protein [Streptomyces
griseoflavus Tu4000]
gi|302478374|gb|EFL41467.1| drug resistance transporter, EmrB/QacA family protein [Streptomyces
griseoflavus Tu4000]
Length=481
Score = 270 bits (690), Expect = 5e-70, Method: Compositional matrix adjust.
Identities = 160/425 (38%), Positives = 239/425 (57%), Gaps = 5/425 (1%)
Query 5 QLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAAT 64
++L L + L ++ LD ++NVALP +QR GLQW + +Y+L +A +M A +
Sbjct 9 RMLVLAICCMSLLIVSLDNTVLNVALPSLQRDLHASTAGLQWTIDAYTLVLASLLMLAGS 68
Query 65 LADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAF 124
AD GRRR ++ G+ +FTLGS+ C LAP + L R Q +G + ++ ++++++ F
Sbjct 69 TADRIGRRRVFMTGLVVFTLGSVLCSLAPDLTSLVVFRMVQAVGGSMLNPVAMSIITNTF 128
Query 125 PEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVE 184
+ +E+ARAIG W A+ I GP +GGLLV+ GWR+IF++NLP+G L LT +V
Sbjct 129 TDPRERARAIGAWGAVVGISMAAGPLVGGLLVESVGWRAIFWINLPVGLAALLLTWRFVP 188
Query 185 ESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLE 244
ES RARR D GQLL IV G+L YA+IE P + A + + E
Sbjct 189 ESRAPRARRPDPVGQLLVIVLFGSLTYAIIEAPHAPLPVIAPFAA--VALLALLALLRYE 246
Query 245 RRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILP 304
R P++DL F ++ A F A+ G L L+T +LQNVRG + GL +LP
Sbjct 247 PRRREPLIDLRFFHSAPFSGATVIAVCAFAALGGFLFLSTLYLQNVRGLSAMEAGLWMLP 306
Query 305 FSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGLCGS 363
+ + +PL G LVG G R+P+L AG M + GLL +F S + +G L G
Sbjct 307 MAVPTFLCAPLSGRLVGSRGPRLPLLIAGAAMTVSGLLFALFEAETSDVTLFLGYVLFGV 366
Query 364 GVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATLEPHL 423
G PIT A++ +P +AG+AS + S R +G +G AV+G+VLAA + ++ P+
Sbjct 367 GFGFVNAPITNTAVSGMPTAQAGVASAVASTSRQLGQALGVAVIGAVLAAGVGSS--PYA 424
Query 424 ERAVP 428
+ VP
Sbjct 425 DAFVP 429
>gi|291439775|ref|ZP_06579165.1| efflux protein [Streptomyces ghanaensis ATCC 14672]
gi|291342670|gb|EFE69626.1| efflux protein [Streptomyces ghanaensis ATCC 14672]
Length=470
Score = 270 bits (689), Expect = 7e-70, Method: Compositional matrix adjust.
Identities = 157/399 (40%), Positives = 231/399 (58%), Gaps = 3/399 (0%)
Query 3 RTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSA 62
R ++L L + L ++ LD ++NVALP +QR F GLQW + +Y+L +A +M A
Sbjct 10 RRRVLVLAICCMSLLIVSLDNTVLNVALPSMQREFHASTSGLQWSIDAYTLVLASLLMLA 69
Query 63 ATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSA 122
+ AD GR+R ++ G+ +FTLGS+ C LAPS+ L R Q +G + ++ ++++++
Sbjct 70 GSTADRIGRKRVFMTGLVVFTLGSLLCSLAPSLEALVVFRMVQAVGGSMLNPVAMSIITN 129
Query 123 AFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCY 182
F + +E+ARAIG W A+ + GP +GGLLV GWRSIF++NLP+G L LTL +
Sbjct 130 TFTDPRERARAIGAWGAVVGLSMAAGPLVGGLLVQSVGWRSIFWINLPVGLAALLLTLRF 189
Query 183 VEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVW 242
V ES RARR D GQLL I G+L YA+IE P ++ +L A++ LF
Sbjct 190 VPESRAPRARRPDPVGQLLVIALFGSLTYAIIEAPHATLPAIAPFAVLALASLVALLFY- 248
Query 243 LERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMI 302
E R +P++DL FR ++ A + F A+ G L LTT +LQNVRG + GL +
Sbjct 249 -EPRRRDPLIDLRFFRSAPFSGATVIAVSAFAALGGFLFLTTLYLQNVRGLSALEAGLWM 307
Query 303 LPFSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGLC 361
LP + + +PL G LVG G R+P+L AG M + GLL +F S A + +G L
Sbjct 308 LPMAVPTFLCAPLSGRLVGSRGPRLPLLIAGGAMTVSGLLFALFEAETSDATLFIGYVLF 367
Query 362 GSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGS 400
G G PIT A++ +P +AG+AS + S R +G
Sbjct 368 GIGFGFVNAPITNTAVSGMPTAQAGVASAVASTSRQLGQ 406
>gi|340776391|ref|ZP_08696334.1| putative efflux membrane protein [Acetobacter aceti NBRC 14818]
Length=479
Score = 269 bits (688), Expect = 7e-70, Method: Compositional matrix adjust.
Identities = 161/416 (39%), Positives = 252/416 (61%), Gaps = 7/416 (1%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
R Q L L + L L ++ +D IVNV LP I+++F GLQW+V +Y+L +A +M+
Sbjct 11 RRHQWLVLASCCLSLLLVMMDVTIVNVVLPSIKQAFGASLSGLQWIVDAYTLTVAALLMA 70
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
A TLAD GRR+ +L G+ +F S CGLA + + AR QG+G A ++ +L++++
Sbjct 71 AGTLADRFGRRKVFLTGIVIFCTASAFCGLALTPTQMIVARILQGVGGAMLNPVALSIIA 130
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
F + ++ARAIG+W ++ I GP +GG + D WR++F++N+P+G + L +T+
Sbjct 131 NTFLDPGDRARAIGLWGMMSGIALALGPAVGGFIADALNWRAVFWINVPVGLIALVMTIR 190
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
+V ES + RFD +GQ L + ALV A+IEGP +GW S + + +L + + +F+
Sbjct 191 FVPESRSPIPARFDPAGQGLAALTSMALVGALIEGPDLGWRSARILGLLILSVLSLVVFL 250
Query 242 WLERRSSNPMMDLTLFRDTSYALA--IATICTVFFAVY-GMLLLTTQFLQNVRGYTPSVT 298
+E+RS++PM++L FR +A A +A +C FAV+ +L L+T +LQ+VRG+ P
Sbjct 251 IVEKRSTHPMLNLGFFRSVPFASATVLAVLC---FAVFSSLLFLSTIYLQDVRGFAPGAA 307
Query 299 GLMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVL-VG 357
G ++PF+ AV I +PL G LV GARVP++ C L G ML +S L L V
Sbjct 308 GWKLMPFAVAVVIAAPLSGRLVAAQGARVPLVLSGCGLAGGAWMLTGLAADTSPLWLAVA 367
Query 358 LGLCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAA 413
L G+G LC PIT A++ +P +AG+A+ + S R IG+ +G A+ GS+ A
Sbjct 368 YALTGAGFGLCNAPITNAAVSGMPRRQAGLAAAVASTSRQIGAALGVAIAGSLRGA 423
>gi|294812525|ref|ZP_06771168.1| Efflux membrane protein [Streptomyces clavuligerus ATCC 27064]
gi|326441022|ref|ZP_08215756.1| efflux membrane protein [Streptomyces clavuligerus ATCC 27064]
gi|294325124|gb|EFG06767.1| Efflux membrane protein [Streptomyces clavuligerus ATCC 27064]
Length=482
Score = 268 bits (685), Expect = 2e-69, Method: Compositional matrix adjust.
Identities = 170/413 (42%), Positives = 239/413 (58%), Gaps = 10/413 (2%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
+R +LL L + L ++ LD I+NVALP I R GLQW + +Y+L +A +M
Sbjct 6 SRRRLLVLAICCMSLLIVSLDNTILNVALPSIGRELNASVTGLQWTIDAYTLVLASLLML 65
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
+ + AD GRRR ++ G++LFTLGS+ C LAPS+ L R Q +G + ++ ++++++
Sbjct 66 SGSTADRIGRRRVFVAGLALFTLGSLLCSLAPSLETLVVFRMVQAVGGSMLNPVAMSIIT 125
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
F + E+ARAIG+W + I GP +GGLLVD GWRSIF+VNLP+G L LTL
Sbjct 126 NTFTDPAERARAIGVWGGVVGISMAAGPLVGGLLVDTVGWRSIFWVNLPVGIAALLLTLR 185
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
YV ES R RR D GQ+L I +G+L YA+IE V A + A +
Sbjct 186 YVPESRAPRPRRPDPVGQVLIIALLGSLTYAIIE---------TDAVFAGIAVLALAGVL 236
Query 242 WLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLM 301
+ E R P++DL FR ++ A F ++ G L L T +LQ+VRGYT GL
Sbjct 237 YYEPRRREPLIDLRFFRSAPFSGATVIAVCAFASLGGFLFLNTLYLQDVRGYTALHAGLY 296
Query 302 ILPFSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
+LP + I SPL G LVG G R+P+L AG M G+L F S+AL+ +G L
Sbjct 297 MLPMAGLTLICSPLSGRLVGSRGPRLPLLIAGTTMGACGVLFAAFEAETSNALLFLGFAL 356
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAA 413
G G L TPIT A++ +P +AG+A+ + S R IG T+G AV+G+VLAA
Sbjct 357 FGIGFGLVNTPITNTAVSGMPRAQAGVAAAVASTSRQIGQTLGVAVIGTVLAA 409
>gi|254389019|ref|ZP_05004249.1| efflux membrane protein [Streptomyces clavuligerus ATCC 27064]
gi|197702736|gb|EDY48548.1| efflux membrane protein [Streptomyces clavuligerus ATCC 27064]
Length=457
Score = 267 bits (683), Expect = 3e-69, Method: Compositional matrix adjust.
Identities = 170/413 (42%), Positives = 239/413 (58%), Gaps = 10/413 (2%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
+R +LL L + L ++ LD I+NVALP I R GLQW + +Y+L +A +M
Sbjct 6 SRRRLLVLAICCMSLLIVSLDNTILNVALPSIGRELNASVTGLQWTIDAYTLVLASLLML 65
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
+ + AD GRRR ++ G++LFTLGS+ C LAPS+ L R Q +G + ++ ++++++
Sbjct 66 SGSTADRIGRRRVFVAGLALFTLGSLLCSLAPSLETLVVFRMVQAVGGSMLNPVAMSIIT 125
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
F + E+ARAIG+W + I GP +GGLLVD GWRSIF+VNLP+G L LTL
Sbjct 126 NTFTDPAERARAIGVWGGVVGISMAAGPLVGGLLVDTVGWRSIFWVNLPVGIAALLLTLR 185
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
YV ES R RR D GQ+L I +G+L YA+IE V A + A +
Sbjct 186 YVPESRAPRPRRPDPVGQVLIIALLGSLTYAIIE---------TDAVFAGIAVLALAGVL 236
Query 242 WLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLM 301
+ E R P++DL FR ++ A F ++ G L L T +LQ+VRGYT GL
Sbjct 237 YYEPRRREPLIDLRFFRSAPFSGATVIAVCAFASLGGFLFLNTLYLQDVRGYTALHAGLY 296
Query 302 ILPFSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
+LP + I SPL G LVG G R+P+L AG M G+L F S+AL+ +G L
Sbjct 297 MLPMAGLTLICSPLSGRLVGSRGPRLPLLIAGTTMGACGVLFAAFEAETSNALLFLGFAL 356
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAA 413
G G L TPIT A++ +P +AG+A+ + S R IG T+G AV+G+VLAA
Sbjct 357 FGIGFGLVNTPITNTAVSGMPRAQAGVAAAVASTSRQIGQTLGVAVIGTVLAA 409
>gi|307727391|ref|YP_003910604.1| drug resistance transporter EmrB/QacA subfamily [Burkholderia
sp. CCGE1003]
gi|307587916|gb|ADN61313.1| drug resistance transporter, EmrB/QacA subfamily [Burkholderia
sp. CCGE1003]
Length=469
Score = 267 bits (682), Expect = 4e-69, Method: Compositional matrix adjust.
Identities = 159/399 (40%), Positives = 238/399 (60%), Gaps = 1/399 (0%)
Query 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60
++R+ L L+AT LG +I LD +VNVAL I+ S A+ L+WVV +Y+L A ++
Sbjct 8 LHRSPRLALLATSLGFVIICLDVTVVNVALARIRASLAMDSTALEWVVNAYTLAFASLLL 67
Query 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120
+A LAD G RR ++ G+++FT SIACG++ S +L +R QG GAA +SLAL+
Sbjct 68 TAGALADHFGARRVFVGGLAVFTCASIACGVSHSATLLIASRLVQGAGAALCVPSSLALL 127
Query 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180
AAFPE E+A+A+ IW A++ GP +GGLLVD +GW SIF +N+P+G ++LTL
Sbjct 128 GAAFPETGERAKAVSIWAGTAALALGAGPLVGGLLVDSFGWPSIFLINVPVGVAGIWLTL 187
Query 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALF 240
+ E+ RR DL+GQ+L +V + AL YAV+E ++GWT+ + +AV ALF
Sbjct 188 AHAPETVVNSRRRIDLAGQMLAVVTLAALTYAVVESGRLGWTNFTVLSAFALSAVMGALF 247
Query 241 VWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGL 300
+ +E R P++ LTLFR+ + ++ T ++ F YG++ + F Q VR TP TGL
Sbjct 248 IAVEARQDQPLLPLTLFRNAAVTVSALTGLSLNFGYYGLMFAMSVFFQYVRHDTPLETGL 307
Query 301 MILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVL-VGLG 359
LP +A VA+ + + G L R G RVP++ G + LG + L+ S LV + L
Sbjct 308 AFLPMTALVALANIVSGRLAARFGYRVPMIYGQVLAALGYVSLLSVSADGSPLVTALPLL 367
Query 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAI 398
G GVAL + I T + V G+ SG++++ R I
Sbjct 368 AVGIGVALAVPSINTAVLANVAPSYVGVGSGVLNSARQI 406
>gi|158318319|ref|YP_001510827.1| EmrB/QacA family drug resistance transporter [Frankia sp. EAN1pec]
gi|158113724|gb|ABW15921.1| drug resistance transporter, EmrB/QacA subfamily [Frankia sp.
EAN1pec]
Length=502
Score = 266 bits (681), Expect = 5e-69, Method: Compositional matrix adjust.
Identities = 154/397 (39%), Positives = 230/397 (58%), Gaps = 1/397 (0%)
Query 14 LGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLADLDGRRR 73
+ L ++ LD IVNVALP ++R GLQW + SY+L +A +M + D GRRR
Sbjct 18 MSLLIVGLDGTIVNVALPALRRDLGASPAGLQWTIDSYTLVLASLLMLGGSTGDRLGRRR 77
Query 74 WYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPEAKEKARA 133
+ G++LFT GS+ C LAP + L R Q +G + ++ ++++++ F + +E+ARA
Sbjct 78 IFQTGLALFTAGSLLCSLAPGLGWLVVFRMVQAVGGSMLNPVAMSIITNTFTDPRERARA 137
Query 134 IGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARR 193
IG+W A+ I GP LGG+LV+ WR+IF++N+P+G L LT +V ES RR
Sbjct 138 IGLWGAVIGISMALGPVLGGILVETVSWRAIFWINIPIGLAALVLTHRFVPESRAPSPRR 197
Query 194 FDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERRSSNPMMD 253
D GQLL I + L Y++IE P GWTS +T+V+L A AL V E R + P++D
Sbjct 198 LDPVGQLLVIAVLATLTYSIIEAPAAGWTSAETLVLLAVAVAAAALLVGYESRRTEPLLD 257
Query 254 LTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFSAAVAIVS 313
+ FR ++ A A F A+ G L L T +LQ+VRGY+ GL+ LP + A +++
Sbjct 258 VRFFRSAPFSGATAIAVCAFGALAGFLFLNTIYLQDVRGYSALHAGLLTLPMALATLVIA 317
Query 314 PLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGLCGSGVALCLTPI 372
PL G VGR G R +L AG+ + M S S ++V L G+G L PI
Sbjct 318 PLSGRAVGRFGPRPSLLAAGVALTAGSAAMTGLSPQTSVTTLMVAYVLFGTGFGLVNAPI 377
Query 373 TTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGS 409
T A++ +P E+AG+A+ + S R +G ++G AV+GS
Sbjct 378 TNTAVSGMPLEQAGVAAAVASTSRQVGQSLGVAVIGS 414
>gi|338778012|gb|EGP42499.1| drug resistance MFS transporter, drug:H+ antiporter 1 [Achromobacter
xylosoxidans AXX-A]
Length=497
Score = 266 bits (679), Expect = 1e-68, Method: Compositional matrix adjust.
Identities = 168/444 (38%), Positives = 248/444 (56%), Gaps = 10/444 (2%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
NR + L + A LG F+ LD IVNVALP +Q + + GLQWVV +Y+L ++ F++S
Sbjct 4 NRRRAL-VFAVNLGSFITILDISIVNVALPTMQAALRIDMAGLQWVVDAYALFLSAFMLS 62
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
A L D GR+R +L GV+LFTLGS CG+A ++ +L R QG+ A + +++L++
Sbjct 63 AGPLGDRYGRKRSWLAGVALFTLGSAFCGMADNLPLLLAGRAVQGVAGALLIPGAMSLLT 122
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
AFP+ E+ARAIG+W + +I GP LGGLLV + W+SIF +NLP+G + + L
Sbjct 123 QAFPDPGERARAIGLWASCNAISLIVGPMLGGLLVAHFSWQSIFLINLPVGVVAIALGAW 182
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
++ES + FD +GQ L ++ +GAL Y +I + GW + T+ L AA+G F+
Sbjct 183 GIQESAHPEHAAFDPAGQALSVIWLGALTYGLIAAGEHGWQAPGTLAALAVAAIGLTAFL 242
Query 242 WLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLM 301
W+E + P++ L LFRD +A + F Y L + +LQ+VRG +P G
Sbjct 243 WVEHTVARPILPLGLFRDAGFASTNFASFVMGFGAYSSLFFFSLYLQHVRGLSPLEAGWQ 302
Query 302 ILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLL-MLIFSEHRSSALVLVGLGL 360
+ P A IVS + G L R G ++AG M+ +L M+ F H AL + L
Sbjct 303 LAPQFVATGIVSTVFGRLNLRFGLPRLMIAGYGMVGAAMLGMMSFDAHTPYALSGSLMVL 362
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSV--------LA 412
G G+ L + + M VP ER+GMAS M+A R G TIG A+LG++ LA
Sbjct 363 LGLGMGLAVPATSMAVMATVPRERSGMASATMNALRQTGMTIGIALLGALMSGCAVDSLA 422
Query 413 AWLSATLEPHLERAVPDPVQRHVL 436
A L+ +P + V +HVL
Sbjct 423 AALTRLGQPDAQAVARIAVTQHVL 446
>gi|298246882|ref|ZP_06970687.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter
racemifer DSM 44963]
gi|297549541|gb|EFH83407.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter
racemifer DSM 44963]
Length=459
Score = 265 bits (678), Expect = 1e-68, Method: Compositional matrix adjust.
Identities = 157/408 (39%), Positives = 236/408 (58%), Gaps = 1/408 (0%)
Query 7 LTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLA 66
L L A G FM+ LD +VNVALP +Q +GLQWVV Y+L A ++SA TL
Sbjct 20 LGLTAICFGFFMVILDTSVVNVALPAMQHDLHGSLEGLQWVVNGYTLIFASLLLSAGTLG 79
Query 67 DLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPE 126
D G +R +L G LFT S+ C LAPS+ +L AR QG+G A + +SL+L++ F
Sbjct 80 DRLGHKRTFLTGYVLFTGASLLCSLAPSLNILIAARILQGVGPALLVPSSLSLITHGFQN 139
Query 127 AKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEES 186
+++ARA+G W + IG GP +GGLLV+ GWRSIF +N+P G L L LT+ +V E+
Sbjct 140 PEKRARAVGFWAGSSGIGLAGGPIVGGLLVETLGWRSIFLLNVPFGLLALALTMRFVSET 199
Query 187 CNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERR 246
++ DL GQ IVA+ L YA+IEG GW S+Q + M F+ +E R
Sbjct 200 PRTTTQKRDLWGQACVIVALATLTYALIEGRSQGWISLQIVGMFLLCIGASGGFLLIETR 259
Query 247 SSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFS 306
S PM+ L F T++++ I C + F +YG+L + + F Q++ Y ++ G+ +LP +
Sbjct 260 HSTPMLPLHFFSSTAFSMPILVGCVLNFGLYGILFVLSLFFQDIYHYPAALAGVALLPIT 319
Query 307 AAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVL-VGLGLCGSGV 365
A + + G + R+G R P++ GL LG L+L+ E S L+L VG + G G
Sbjct 320 VATGSTALISGRITARLGTRRPMIGGLAASCLGTLLLLLGETGDSILLLTVGEIVIGLGC 379
Query 366 ALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAA 413
+ + +TT + VP + G+AS +++A R +G +G A+LGS+L +
Sbjct 380 GMTVPAMTTAILNTVPKSQVGVASALLNASRQLGGVLGVAILGSILGS 427
>gi|296136482|ref|YP_003643724.1| major facilitator superfamily MFS_1 [Thiomonas intermedia K12]
gi|295796604|gb|ADG31394.1| major facilitator superfamily MFS_1 [Thiomonas intermedia K12]
Length=472
Score = 265 bits (676), Expect = 2e-68, Method: Compositional matrix adjust.
Identities = 157/406 (39%), Positives = 240/406 (60%), Gaps = 5/406 (1%)
Query 8 TLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLAD 67
TLIA LG ++ LD VNVAL + R FA GLQWVV +Y+L A ++++ +L D
Sbjct 21 TLIAAALGFVVVLLDVSAVNVALGALHRDFATAVAGLQWVVNAYTLVFAALLLTSGSLGD 80
Query 68 LDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPEA 127
G RR +L G +LFTL S AC +A ++ +L AR +GLGA+ + SLA++ AFP+
Sbjct 81 RLGSRRVFLCGFTLFTLASAACSVAINLPMLVVARLVEGLGASLLVPNSLAILKRAFPDK 140
Query 128 KEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESC 187
+++RA+G W AI I GP LGGLLV WGWRSIF +NLP+G + +LTL YV
Sbjct 141 LQRSRAVGWWGAIGGISLAAGPVLGGLLVTHWGWRSIFLINLPIGLVGGYLTLQYVAADG 200
Query 188 NERARR----FDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWL 243
+ R D GQL+ I+++ A A+ E Q+GW SV L A V A F+W+
Sbjct 201 SRHPRHHDDGLDWPGQLVAILSLAAFTAALTEAGQLGWGSVWVQGGLLLAVVAAAGFIWI 260
Query 244 ERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMIL 303
E RS +PM+ L LFR +++ +A + V F+ YG++ + + F Q + +P TG+ L
Sbjct 261 ESRSRSPMLPLGLFRVSAFTIATISGVIVNFSYYGLIFIFSLFFQIEQQLSPQQTGMAFL 320
Query 304 PFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLI-FSEHRSSALVLVGLGLCG 362
P + + V+ L G L+ R+GA+ ++ GL + G L+L+ + ++V + +
Sbjct 321 PMTIVLMGVNVLAGRLISRMGAKRLMVLGLLIAASGYLLLLPVRVDGAYGWLVVPMLIAS 380
Query 363 SGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLG 408
SG+AL + +T V +++V RAG+ASG++++ R +G +G AV G
Sbjct 381 SGIALMVPTMTNVTLSSVDDSRAGIASGVLNSARQVGGLLGVAVFG 426
>gi|337764480|emb|CCB73189.1| putative efflux protein [Streptomyces cattleya NRRL 8057]
Length=483
Score = 264 bits (674), Expect = 3e-68, Method: Compositional matrix adjust.
Identities = 158/415 (39%), Positives = 231/415 (56%), Gaps = 1/415 (0%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
R + + L +F+ L+ ++NVALP +QR GLQW +Y + +A +M
Sbjct 6 RRRRRMVLAVCCTSVFIGNLNNTVLNVALPAMQRDLHSSLSGLQWTTDAYLIVLAALLML 65
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
A + D GRRR + G+ +FTLGS+ CGLAP + LT R Q +GA+ ++ ++++++
Sbjct 66 AGSAGDRLGRRRVFQTGLVVFTLGSLLCGLAPGLGWLTGFRVLQAIGASMLNPVAMSIIT 125
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
F E+ARAIG+W A+ + GP +GG+LV GWRSIF++NLP+G +
Sbjct 126 NVFTGRSERARAIGVWGAVMGVAMAAGPLVGGVLVQAAGWRSIFWLNLPIGLAAVVCAAR 185
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
+V ES RR D GQLL +V + +L YA+IE P GW + T+ A +
Sbjct 186 FVPESRAAVPRRMDPVGQLLVVVLMASLTYAIIEAPATGWGAPATLGCAVAAGAALIGLI 245
Query 242 WLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLM 301
ERR S P++DL +FR +++ A A FF + G L L T +LQNVRG + G
Sbjct 246 GYERRRSEPLVDLRVFRSAAFSGASAMAVCSFFVLGGFLFLNTLYLQNVRGLSALAAGAY 305
Query 302 ILPFSAAVAIVSPLVGHLVGRIGARVP-ILAGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
+LP + + SP+ G L G R+P +LAG GLL+ S+AL+ L
Sbjct 306 LLPMAGMNILTSPVSGRLTATCGPRLPLLLAGAATTGGGLLLAAADAETSNALLFPAYCL 365
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWL 415
G GV L TP+T AMT +P E+AG+A+ ++S R G +G AVLG+VLAA L
Sbjct 366 IGIGVGLANTPVTNAAMTGMPTEQAGVAAAVVSTCRQFGQALGVAVLGAVLAAGL 420
>gi|298251556|ref|ZP_06975359.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter
racemifer DSM 44963]
gi|297546148|gb|EFH80016.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter
racemifer DSM 44963]
Length=490
Score = 263 bits (672), Expect = 6e-68, Method: Compositional matrix adjust.
Identities = 158/410 (39%), Positives = 238/410 (59%), Gaps = 5/410 (1%)
Query 7 LTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLA 66
L LI + +F++ +D I+NVALP IQ F QW + +Y+L +A ++ +++ A
Sbjct 24 LILIICCVSVFLVGVDTSILNVALPSIQHDFHASIAEAQWTLDAYTLVIASLLVLSSSTA 83
Query 67 DLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPE 126
D GRRR + +GVSLFTLGS+ C LAPSI L R Q +G + ++ +++++ F +
Sbjct 84 DRVGRRRIFQLGVSLFTLGSLLCSLAPSITWLIVFRMMQAVGGSMLNPVAMSIIGNTFIK 143
Query 127 AKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEES 186
E+ARA+G+W +A I GP LGGLLVD GWRSIF++N+P G V+ LT +V ES
Sbjct 144 PAERARAVGVWGGVAGISLAAGPILGGLLVDSIGWRSIFWINVPFGIAVILLTAKFVPES 203
Query 187 CNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERR 246
RRFD GQ+L I +G L+Y +IE P GWTS + + L AA F+ ER
Sbjct 204 KAPHPRRFDPIGQILVIALLGLLIYGIIEVPAYGWTSFEILACLIGAAACFVGFIAYERV 263
Query 247 SSNPMMDLTLFRDTSYALA-IATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPF 305
P++D+ FR ++ A I +CT F A+ G +L T +LQ++ ++P G LP
Sbjct 264 RKEPLIDIRFFRSVPFSGASIIALCT-FTALGGFSILNTLYLQDILHFSPLQAGTAFLPM 322
Query 306 SAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALV--LVGLGLCGS 363
+ A+AI SP+ G ++GR G R+ +L + +L E+ + + LV L GS
Sbjct 323 AVALAISSPISGRIIGRYGTRISLLI-GGAAIAIAGLLAAIEYNNLPFIGLLVCYALVGS 381
Query 364 GVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAA 413
GV I+ A++ +P +AG A+GI S R +G +G AV+GSV+A+
Sbjct 382 GVGWINAAISNTALSGMPRSQAGAAAGIASTMRQLGQALGVAVIGSVIAS 431
>gi|345015034|ref|YP_004817388.1| EmrB/QacA subfamily drug resistance transporter [Streptomyces
violaceusniger Tu 4113]
gi|344041383|gb|AEM87108.1| drug resistance transporter, EmrB/QacA subfamily [Streptomyces
violaceusniger Tu 4113]
Length=496
Score = 263 bits (671), Expect = 8e-68, Method: Compositional matrix adjust.
Identities = 145/407 (36%), Positives = 227/407 (56%), Gaps = 1/407 (0%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
+R ++L L + L ++ LD ++NVALP I+ G+QW + +Y+L +A +M
Sbjct 6 HRRRMLVLAICCMSLLLVSLDNTVLNVALPSIRSDLHASVSGMQWTIDAYTLVLAALLML 65
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
+ + AD GR+R + G+ +FTLGS C LAP++ L R Q +G + ++ ++++++
Sbjct 66 SGSTADRVGRKRTFQTGLVIFTLGSGLCSLAPNLETLVIFRMVQAIGGSMLNPVAMSIIT 125
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
F E KE+ARAIG+W + I GP +GG+LV+ GWRSIF++NLP+G L LT
Sbjct 126 NVFTEPKERARAIGVWGGVVGISMAAGPIVGGVLVESVGWRSIFWINLPVGVAALLLTAR 185
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
YV ES + RR D GQLL + +G L YA+IE P GW S + AAVG +
Sbjct 186 YVPESRAPKPRRADPVGQLLVVAVLGTLTYAIIEAPDRGWDSPLIVTFAAIAAVGLIALI 245
Query 242 WLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLM 301
E R P++DL F ++ A F A+ G L + T +LQ+VRG GL
Sbjct 246 RYELRREEPLIDLRFFHSAPFSGATVVAVCAFAALSGYLFMNTLYLQDVRGLDALHAGLW 305
Query 302 ILPFSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
+LP + + +PL G LVG G R +L AG+ + G++ +F + +L+G +
Sbjct 306 MLPMAFMCFVCAPLSGRLVGARGPRPSMLVAGVAITASGVMFAVFDVQTTDIGLLLGYAM 365
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVL 407
G G + PIT A++ +P +AG+A+ + S R +G ++G AV+
Sbjct 366 FGLGFGMVNAPITNTAVSGMPRSQAGVAAAVASTSRQVGQSLGVAVI 412
>gi|295680907|ref|YP_003609481.1| major facilitator superfamily MFS_1 [Burkholderia sp. CCGE1002]
gi|295440802|gb|ADG19970.1| major facilitator superfamily MFS_1 [Burkholderia sp. CCGE1002]
Length=464
Score = 263 bits (671), Expect = 9e-68, Method: Compositional matrix adjust.
Identities = 160/397 (41%), Positives = 235/397 (60%), Gaps = 1/397 (0%)
Query 3 RTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSA 62
R+ L L+AT LG +I LD +VNVAL ++ S + L+WVV +Y+L A ++SA
Sbjct 10 RSPRLALLATSLGFVIICLDVTVVNVALARMRDSLGLDSTALEWVVNAYTLAFASLLLSA 69
Query 63 ATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSA 122
LAD G RR +L G +FT S+ CGL+ A+L AR QG+GAA +SLAL+ A
Sbjct 70 GALADRFGARRIFLAGFVVFTCASVGCGLSDGAALLVGARVVQGIGAALCVPSSLALLGA 129
Query 123 AFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCY 182
AFP+ +ARA+ +W A++ GP +GG+LVD++GW +IF +N+P+G + ++LT+ +
Sbjct 130 AFPDPHARARAVSVWAGTAALALGAGPLVGGVLVDRFGWPAIFLINVPIGVVGIWLTIAH 189
Query 183 VEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVW 242
E+ ARR DL+GQ L +VA+ L YAV+E ++GWT + + L AAV LFV
Sbjct 190 APETKGHAARRVDLAGQTLAVVALVGLTYAVVESGRLGWTGMTVLTGLGVAAVAGGLFVI 249
Query 243 LERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMI 302
+E R + P++ L LFR + +++ T ++ F YG++ + F QN R TP TGL
Sbjct 250 VEARQAQPLLPLALFRHAAVSVSALTGLSLNFGYYGLMFAMSLFFQNARHDTPLETGLAF 309
Query 303 LPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSAL-VLVGLGLC 361
LP +A VA+ + G L R G R+P+L G + LG + L F SSAL V + L
Sbjct 310 LPMTAVVAVANVASGSLTARFGYRLPMLVGQALASLGYVSLAFVRVDSSALAVALPLLSV 369
Query 362 GSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAI 398
G GVAL + I T + V G+ASG+++ R I
Sbjct 370 GVGVALAVPSINTAVLAHVEPSYMGIASGVLNTARQI 406
>gi|336116572|ref|YP_004571339.1| putative drug resistance transporter [Microlunatus phosphovorus
NM-1]
gi|334684351|dbj|BAK33936.1| putative drug resistance transporter [Microlunatus phosphovorus
NM-1]
Length=457
Score = 260 bits (665), Expect = 4e-67, Method: Compositional matrix adjust.
Identities = 158/403 (40%), Positives = 233/403 (58%), Gaps = 10/403 (2%)
Query 14 LGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMSAATLADLDGRRR 73
LG F++ LDA IVNVALP I+ G GLQW+V Y+L + + TL+D G RR
Sbjct 27 LGFFVVALDAQIVNVALPHIRADLGGGLSGLQWIVTGYTLMFSALQLFGGTLSDRIGARR 86
Query 74 WYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVSAAFPEAKEKARA 133
Y IG+++F GS ACG APS+ VL R QG+GAA ++ TSLAL+ AF +A ++ RA
Sbjct 87 AYGIGMAVFVAGSAACGAAPSLTVLIAGRVVQGIGAAMITPTSLALIREAFLDAVQRGRA 146
Query 134 IGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLCYVEESCNERARR 193
I W S+ GP LGG+L Q+GWR IF VNLP+G +V + L V S R
Sbjct 147 ITYWALGGSVAAAAGPVLGGVL-TQFGWRWIFLVNLPVG-IVALIVLARVTPSAG-RVAP 203
Query 194 FDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFVWLERRSSNPMMD 253
FD +GQ+ I A+G L + +IEG +G+ + + + A +G +F+ + R +PMM
Sbjct 204 FDWAGQIAAIAALGGLTFGIIEGGSVGYAAPEVLAAFVVAIIGAIIFLIAQARGRHPMMP 263
Query 254 LTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLMILPFSAAVAIVS 313
L LFR + + + A YG++ + + + Q RG + VTGL+ LP + VAI +
Sbjct 264 LDLFRSGTVSTGLGIAFVTMAAFYGVVFVQSLYFQEQRGASALVTGLLFLPMTGLVAIFN 323
Query 314 PLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRS----SALVLVGLGLCGSGVALCL 369
P V + R+G V + G+ ++ LGL+ L + +AL++V +GL GS +
Sbjct 324 PFVARAMERLGKIVTTIGGMVLMALGLIALACLPADAPILVAALLMVPVGLGGS---FTV 380
Query 370 TPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLA 412
P+T + + VPA RAG ASGI++ R +G ++G A+ G+VLA
Sbjct 381 PPVTALILDQVPAARAGTASGILNTARQMGGSLGIAIFGAVLA 423
>gi|32141172|ref|NP_733574.1| efflux protein [Streptomyces coelicolor A3(2)]
gi|289771764|ref|ZP_06531142.1| efflux protein [Streptomyces lividans TK24]
gi|24413772|emb|CAD55309.1| putative efflux protein [Streptomyces coelicolor A3(2)]
gi|289701963|gb|EFD69392.1| efflux protein [Streptomyces lividans TK24]
Length=481
Score = 260 bits (665), Expect = 4e-67, Method: Compositional matrix adjust.
Identities = 148/401 (37%), Positives = 231/401 (58%), Gaps = 3/401 (0%)
Query 2 NRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIMS 61
+R ++L L + L ++ +D I+NVALP +QR GLQW + +Y+L +A +M
Sbjct 6 HRRRMLVLAICCMSLLIVSIDNTILNVALPSMQRDLHASTSGLQWAIDAYTLVLAALLML 65
Query 62 AATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALVS 121
+ + AD GR+R ++ G+ +FTLGS+ C LAP ++ L R Q +G + ++ ++++++
Sbjct 66 SGSTADRIGRKRVFMTGLVIFTLGSLLCSLAPGLSSLIVFRMMQAVGGSMLNPVAMSIIT 125
Query 122 AAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTLC 181
F + +E+ARAIG+W A+ I GP +GG+LV+ GWRSIF+VNLP+G L LTL
Sbjct 126 NTFTDPRERARAIGVWGAVVGISMAAGPLVGGVLVESVGWRSIFWVNLPVGLAALLLTLR 185
Query 182 YVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTIVMLWTAAVGCALFV 241
+V ES +ARR D GQL+ IV G+L YA+IE P G+ +V + A +
Sbjct 186 FVPESRAPKARRPDPLGQLMVIVLFGSLTYAIIEAPNAGFRTVLPFAV--LALAALIGLL 243
Query 242 WLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTGLM 301
E R ++P+++L FR ++ A + F A+ G L L+T +LQNVRG + GL
Sbjct 244 LHEPRRTDPLIELRFFRSAPFSGATVIAISAFAALGGFLFLSTLYLQNVRGLSALEAGLW 303
Query 302 ILPFSAAVAIVSPLVGHLVGRIGARVPIL-AGLCMLMLGLLMLIFSEHRSSALVLVGLGL 360
+LP + + +PL G LVG G R+P+L AG + + G L F S + +G L
Sbjct 304 MLPMAVPTFLCAPLSGRLVGSRGPRLPLLIAGGALTVSGTLFAAFEAETSDLTLFLGYVL 363
Query 361 CGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGST 401
G G PIT A++ +P +AG+A+ + S R +G T
Sbjct 364 FGIGFGFVNAPITNTAVSGMPRSQAGVAAAVASTSRQLGQT 404
Lambda K H
0.326 0.138 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 1180538684976
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40