BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2348c

Length=108
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609485|ref|NP_216864.1|  hypothetical protein Rv2348c [Mycob...   205    1e-51
gi|289553865|ref|ZP_06443075.1|  hypothetical protein TBXG_01615 ...   202    1e-50
gi|148823549|ref|YP_001288303.1|  hypothetical protein TBFG_12372...   191    3e-47
gi|167969904|ref|ZP_02552181.1|  hypothetical protein MtubH3_1849...   167    6e-40
gi|298525833|ref|ZP_07013242.1|  predicted protein [Mycobacterium...   137    5e-31
gi|240173289|ref|ZP_04751947.1|  hypothetical protein MkanA1_2851...   119    2e-25
gi|183983635|ref|YP_001851926.1|  hypothetical protein MMAR_3655 ...   115    3e-24
gi|41408233|ref|NP_961069.1|  hypothetical protein MAP2135c [Myco...  97.4    6e-19
gi|296166321|ref|ZP_06848758.1|  conserved hypothetical protein [...  85.9    2e-15
gi|118464811|ref|YP_881258.1|  hypothetical protein MAV_2040 [Myc...  70.9    7e-11
gi|342857483|ref|ZP_08714139.1|  hypothetical protein MCOL_01365 ...  68.2    4e-10
gi|254774764|ref|ZP_05216280.1|  hypothetical protein MaviaA2_088...  46.2    0.002
gi|254819375|ref|ZP_05224376.1|  hypothetical protein MintA_05595...  39.3    0.21 


>gi|15609485|ref|NP_216864.1| hypothetical protein Rv2348c [Mycobacterium tuberculosis H37Rv]
 gi|15841855|ref|NP_336892.1| hypothetical protein MT2413 [Mycobacterium tuberculosis CDC1551]
 gi|148662176|ref|YP_001283699.1| hypothetical protein MRA_2368 [Mycobacterium tuberculosis H37Ra]
 55 more sequence titles
 Length=108

 Score =  205 bits (522),  Expect = 1e-51, Method: Compositional matrix adjust.
 Identities = 107/108 (99%), Positives = 108/108 (100%), Gaps = 0/108 (0%)

Query  1    VLLPLGPPLPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAA  60
            +LLPLGPPLPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAA
Sbjct  1    MLLPLGPPLPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAA  60

Query  61   EGADAEAAAMDEWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG  108
            EGADAEAAAMDEWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG
Sbjct  61   EGADAEAAAMDEWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG  108


>gi|289553865|ref|ZP_06443075.1| hypothetical protein TBXG_01615 [Mycobacterium tuberculosis KZN 
605]
 gi|289438497|gb|EFD20990.1| hypothetical protein TBXG_01615 [Mycobacterium tuberculosis KZN 
605]
Length=106

 Score =  202 bits (515),  Expect = 1e-50, Method: Compositional matrix adjust.
 Identities = 105/106 (99%), Positives = 106/106 (100%), Gaps = 0/106 (0%)

Query  3    LPLGPPLPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEG  62
            +PLGPPLPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEG
Sbjct  1    MPLGPPLPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEG  60

Query  63   ADAEAAAMDEWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG  108
            ADAEAAAMDEWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG
Sbjct  61   ADAEAAAMDEWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG  106


>gi|148823549|ref|YP_001288303.1| hypothetical protein TBFG_12372 [Mycobacterium tuberculosis F11]
 gi|253798578|ref|YP_003031579.1| hypothetical protein TBMG_01630 [Mycobacterium tuberculosis KZN 
1435]
 gi|254365126|ref|ZP_04981172.1| hypothetical protein TBHG_02287 [Mycobacterium tuberculosis str. 
Haarlem]
 gi|294994550|ref|ZP_06800241.1| hypothetical protein Mtub2_08538 [Mycobacterium tuberculosis 
210]
 gi|134150640|gb|EBA42685.1| hypothetical protein TBHG_02287 [Mycobacterium tuberculosis str. 
Haarlem]
 gi|148722076|gb|ABR06701.1| hypothetical protein TBFG_12372 [Mycobacterium tuberculosis F11]
 gi|253320081|gb|ACT24684.1| hypothetical protein TBMG_01630 [Mycobacterium tuberculosis KZN 
1435]
Length=100

 Score =  191 bits (485),  Expect = 3e-47, Method: Compositional matrix adjust.
 Identities = 99/100 (99%), Positives = 100/100 (100%), Gaps = 0/100 (0%)

Query  9    LPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAA  68
            +PPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAA
Sbjct  1    MPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAA  60

Query  69   AMDEWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG  108
            AMDEWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG
Sbjct  61   AMDEWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG  100


>gi|167969904|ref|ZP_02552181.1| hypothetical protein MtubH3_18499 [Mycobacterium tuberculosis 
H37Ra]
 gi|254551396|ref|ZP_05141843.1| hypothetical protein Mtube_13199 [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
 gi|297634946|ref|ZP_06952726.1| hypothetical protein MtubK4_12526 [Mycobacterium tuberculosis 
KZN 4207]
 gi|297731937|ref|ZP_06961055.1| hypothetical protein MtubKR_12648 [Mycobacterium tuberculosis 
KZN R506]
 gi|313659272|ref|ZP_07816152.1| hypothetical protein MtubKV_12663 [Mycobacterium tuberculosis 
KZN V2475]
Length=86

 Score =  167 bits (422),  Expect = 6e-40, Method: Compositional matrix adjust.
 Identities = 86/86 (100%), Positives = 86/86 (100%), Gaps = 0/86 (0%)

Query  23   MLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAAAMDEWDEWQAWNEW  82
            MLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAAAMDEWDEWQAWNEW
Sbjct  1    MLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAAAMDEWDEWQAWNEW  60

Query  83   VAENAEPRFEVPRSSSSVIPHSPAAG  108
            VAENAEPRFEVPRSSSSVIPHSPAAG
Sbjct  61   VAENAEPRFEVPRSSSSVIPHSPAAG  86


>gi|298525833|ref|ZP_07013242.1| predicted protein [Mycobacterium tuberculosis 94_M4241A]
 gi|298495627|gb|EFI30921.1| predicted protein [Mycobacterium tuberculosis 94_M4241A]
Length=76

 Score =  137 bits (346),  Expect = 5e-31, Method: Compositional matrix adjust.
 Identities = 72/73 (99%), Positives = 73/73 (100%), Gaps = 0/73 (0%)

Query  1   VLLPLGPPLPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAA  60
           +LLPLGPPLPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAA
Sbjct  1   MLLPLGPPLPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAA  60

Query  61  EGADAEAAAMDEW  73
           EGADAEAAAMDEW
Sbjct  61  EGADAEAAAMDEW  73


>gi|240173289|ref|ZP_04751947.1| hypothetical protein MkanA1_28511 [Mycobacterium kansasii ATCC 
12478]
Length=116

 Score =  119 bits (298),  Expect = 2e-25, Method: Compositional matrix adjust.
 Identities = 66/97 (69%), Positives = 70/97 (73%), Gaps = 1/97 (1%)

Query  12   DAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAAAMD  71
            DAV AKR ESGMLGGLSVPLSWG AVPPDDYDHWA   E      V  A   +   ++ D
Sbjct  21   DAVSAKRGESGMLGGLSVPLSWGTAVPPDDYDHWAKEDEAAEVAVVPGAVDPEPAESSTD  80

Query  72   EWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG  108
            EWDEW  WNEW A NAEPRFEVPR SS V+PHSPAAG
Sbjct  81   EWDEWAEWNEWEAANAEPRFEVPR-SSRVVPHSPAAG  116


>gi|183983635|ref|YP_001851926.1| hypothetical protein MMAR_3655 [Mycobacterium marinum M]
 gi|183176961|gb|ACC42071.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=105

 Score =  115 bits (287),  Expect = 3e-24, Method: Compositional matrix adjust.
 Identities = 66/97 (69%), Positives = 71/97 (74%), Gaps = 3/97 (3%)

Query  12   DAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAAAMD  71
            DAV AKR ESG+L GLSVPLSWG AVPPDDYDHWAP PE     +    E  DA AA  D
Sbjct  12   DAVAAKRGESGLLCGLSVPLSWGTAVPPDDYDHWAPEPE--EGAEAVVEENVDAAAAGTD  69

Query  72   EWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG  108
            EWDEW  W EW A NAEP FE+PR +SSVIP+SPAAG
Sbjct  70   EWDEWAEWREWEAANAEPHFEMPR-TSSVIPNSPAAG  105


>gi|41408233|ref|NP_961069.1| hypothetical protein MAP2135c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41396588|gb|AAS04452.1| hypothetical protein MAP_2135c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=143

 Score = 97.4 bits (241),  Expect = 6e-19, Method: Compositional matrix adjust.
 Identities = 60/108 (56%), Positives = 65/108 (61%), Gaps = 13/108 (12%)

Query  1    VLLPLGPPLPPDAVVAKRAESGMLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAA  60
            VLLPLG PLP D V A R ESG+LGGLSVPL WGVAVPPDDYDHWAP PE  A+   + A
Sbjct  49   VLLPLGSPLPDDTVSAVRGESGVLGGLSVPLKWGVAVPPDDYDHWAPKPEASAEAVEETA  108

Query  61   EGADAEAAAMDEWDEWQAWNEWVAENAEPRFEVPRSSSSVIPHSPAAG  108
            E     A A   W  W          A PR      ++ VIPHSPAAG
Sbjct  109  EMPRPTAVADGVWSGWDG-------EAVPR------TAGVIPHSPAAG  143


>gi|296166321|ref|ZP_06848758.1| conserved hypothetical protein [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295898330|gb|EFG77899.1| conserved hypothetical protein [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=82

 Score = 85.9 bits (211),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 52/87 (60%), Positives = 58/87 (67%), Gaps = 6/87 (6%)

Query  23   MLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADV-DVQAAEGADAEAAAMDEWDEWQAWNE  81
            MLGGLSVPL WGVAVPPDDYDHWAP  E  AD  D  A   A A  +  ++W+EW+ W  
Sbjct  1    MLGGLSVPLKWGVAVPPDDYDHWAPKTEANADAGDPVADTPAPAAVSDANQWNEWKRWE-  59

Query  82   WVAENAEPRFEVPRSSSSVIPHSPAAG  108
                 AEP FE+PR S  VIPHSPAAG
Sbjct  60   ---GEAEPHFEMPR-SGGVIPHSPAAG  82


>gi|118464811|ref|YP_881258.1| hypothetical protein MAV_2040 [Mycobacterium avium 104]
 gi|118166098|gb|ABK66995.1| conserved hypothetical protein [Mycobacterium avium 104]
 gi|336461680|gb|EGO40543.1| hypothetical protein MAPs_28430 [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=73

 Score = 70.9 bits (172),  Expect = 7e-11, Method: Compositional matrix adjust.
 Identities = 45/86 (53%), Positives = 49/86 (57%), Gaps = 13/86 (15%)

Query  23   MLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAAAMDEWDEWQAWNEW  82
            MLGGLSVPL WGVAVPPDDYDHWAP PE  A+   + AE     A A   W  W      
Sbjct  1    MLGGLSVPLKWGVAVPPDDYDHWAPKPEASAEAVEETAEMPRPTAVADGVWSGWDG----  56

Query  83   VAENAEPRFEVPRSSSSVIPHSPAAG  108
                A PR      ++ VIPHSPAAG
Sbjct  57   ---EAVPR------TAGVIPHSPAAG  73


>gi|342857483|ref|ZP_08714139.1| hypothetical protein MCOL_01365 [Mycobacterium colombiense CECT 
3035]
 gi|342134816|gb|EGT87982.1| hypothetical protein MCOL_01365 [Mycobacterium colombiense CECT 
3035]
Length=73

 Score = 68.2 bits (165),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 44/86 (52%), Positives = 48/86 (56%), Gaps = 13/86 (15%)

Query  23   MLGGLSVPLSWGVAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAAAMDEWDEWQAWNEW  82
            MLGGLSVPL WGV VPPDDYDHWAP P+ GA+   + A+     A A   W  W      
Sbjct  1    MLGGLSVPLKWGVVVPPDDYDHWAPKPDAGAEAPEEMADVPRPTAVADGVWTGWDG----  56

Query  83   VAENAEPRFEVPRSSSSVIPHSPAAG  108
                      VPR S  VIPHSPAAG
Sbjct  57   --------DTVPR-SPGVIPHSPAAG  73


>gi|254774764|ref|ZP_05216280.1| hypothetical protein MaviaA2_08843 [Mycobacterium avium subsp. 
avium ATCC 25291]
Length=61

 Score = 46.2 bits (108),  Expect = 0.002, Method: Compositional matrix adjust.
 Identities = 33/74 (45%), Positives = 38/74 (52%), Gaps = 13/74 (17%)

Query  35   VAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAAAMDEWDEWQAWNEWVAENAEPRFEVP  94
            +AVPPDDYDHWAP PE  A+   + AE     A A   W  W          A PR    
Sbjct  1    MAVPPDDYDHWAPKPEASAEAVEETAEMPRPTAVADGVWSGWDG-------EAVPR----  49

Query  95   RSSSSVIPHSPAAG  108
              ++ VIPHSPAAG
Sbjct  50   --TAGVIPHSPAAG  61


>gi|254819375|ref|ZP_05224376.1| hypothetical protein MintA_05595 [Mycobacterium intracellulare 
ATCC 13950]
Length=61

 Score = 39.3 bits (90),  Expect = 0.21, Method: Compositional matrix adjust.
 Identities = 27/74 (37%), Positives = 32/74 (44%), Gaps = 13/74 (17%)

Query  35   VAVPPDDYDHWAPAPEDGADVDVQAAEGADAEAAAMDEWDEWQAWNEWVAENAEPRFEVP  94
            + VPPDDYDHWAP  +  AD   +  +     A A   W  W+              E  
Sbjct  1    MVVPPDDYDHWAPKSDASADTTEETLDAPRPTAVADGVWSGWEG-------------EAA  47

Query  95   RSSSSVIPHSPAAG  108
                 VIPHSPAAG
Sbjct  48   ARPVGVIPHSPAAG  61



Lambda     K      H
   0.311    0.131    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 129996839040


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40