BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2349c Length=508 Score E Sequences producing significant alignments: (Bits) Value gi|254551397|ref|ZP_05141844.1| phospholipase C 3 plcC [Mycobact... 1039 0.0 gi|148823550|ref|YP_001288304.1| phospholipase C 3 plcC [Mycobac... 1039 0.0 gi|15609486|ref|NP_216865.1| phospholipase C 3 PLCC [Mycobacteri... 1037 0.0 gi|294994549|ref|ZP_06800240.1| phospholipase C 3 plcC [Mycobact... 1036 0.0 gi|289575041|ref|ZP_06455268.1| phospholipase C 3 plcC [Mycobact... 1035 0.0 gi|289758474|ref|ZP_06517852.1| conserved hypothetical protein [... 1034 0.0 gi|240173290|ref|ZP_04751948.1| phospholipase C 3 plcC [Mycobact... 925 0.0 gi|183983636|ref|YP_001851927.1| membrane-associated phospholipa... 912 0.0 gi|289750954|ref|ZP_06510332.1| phospholipase C 3 plcC [Mycobact... 885 0.0 gi|240173292|ref|ZP_04751950.1| membrane-associated phospholipas... 709 0.0 gi|289745624|ref|ZP_06505002.1| phospholipase C 2 [Mycobacterium... 702 0.0 gi|339298872|gb|AEJ50982.1| phospholipase C [Mycobacterium tuber... 699 0.0 gi|308380173|ref|ZP_07669139.1| putative Tat (twin-arginine tran... 699 0.0 gi|289758476|ref|ZP_06517854.1| conserved hypothetical protein [... 698 0.0 gi|15841221|ref|NP_336258.1| phospholipase C [Mycobacterium tube... 698 0.0 gi|15841858|ref|NP_336895.1| phospholipase C [Mycobacterium tube... 697 0.0 gi|15609488|ref|NP_216867.1| membrane-associated phospholipase C... 697 0.0 gi|183983637|ref|YP_001851928.1| membrane-associated phospholipa... 697 0.0 gi|254231948|ref|ZP_04925275.1| phospholipase C 4 (fragment) plc... 687 0.0 gi|217069518|gb|ACJ83246.1| Rv2349c antigen [Mycobacterium tuber... 687 0.0 gi|183983547|ref|YP_001851838.1| membrane-associated phospholipa... 686 0.0 gi|118618235|ref|YP_906567.1| membrane-associated phospholipase ... 685 0.0 gi|240170410|ref|ZP_04749069.1| membrane-associated phospholipas... 682 0.0 gi|240173291|ref|ZP_04751949.1| membrane-associated phospholipas... 680 0.0 gi|183983797|ref|YP_001852088.1| membrane-associated phospholipa... 677 0.0 gi|183981500|ref|YP_001849791.1| membrane-associated phospholipa... 673 0.0 gi|240169308|ref|ZP_04747967.1| membrane-associated phospholipas... 672 0.0 gi|339295253|gb|AEJ47364.1| membrane-associated phospholipase C ... 672 0.0 gi|15609487|ref|NP_216866.1| membrane-associated phospholipase C... 670 0.0 gi|148823551|ref|YP_001288305.1| membrane-associated phospholipa... 670 0.0 gi|306780388|ref|ZP_07418725.1| membrane-associated phospholipas... 669 0.0 gi|308370983|ref|ZP_07423455.2| membrane-associated phospholipas... 669 0.0 gi|1399494|gb|AAC18944.1| phospholipase C [Mycobacterium tubercu... 649 0.0 gi|254232495|ref|ZP_04925822.1| membrane-associated phospholipas... 645 0.0 gi|183984690|ref|YP_001852981.1| membrane-associated phospholipa... 645 0.0 gi|183980315|ref|YP_001848606.1| membrane-associated phospholipa... 640 0.0 gi|340626764|ref|YP_004745216.1| phospholipase c 4 [Mycobacteriu... 613 2e-173 gi|333918704|ref|YP_004492285.1| phospholipase C [Amycolicicoccu... 522 5e-146 gi|111019467|ref|YP_702439.1| phospholipase C [Rhodococcus josti... 513 4e-143 gi|226361617|ref|YP_002779395.1| phospholipase C [Rhodococcus op... 509 4e-142 gi|308401612|ref|ZP_07669413.1| phosphoesterase family protein [... 480 3e-133 gi|148661554|ref|YP_001283077.1| putative phospholipase C 4 PlcD... 453 3e-125 gi|289575348|ref|ZP_06455575.1| predicted protein [Mycobacterium... 388 1e-105 gi|15608893|ref|NP_216271.1| phospholipase C 4 PLCD [Mycobacteri... 363 3e-98 gi|256389818|ref|YP_003111382.1| phospholipase C [Catenulispora ... 358 1e-96 gi|329937895|ref|ZP_08287377.1| phospholipase C [Streptomyces gr... 332 1e-88 gi|298525835|ref|ZP_07013244.1| predicted protein [Mycobacterium... 324 2e-86 gi|302544869|ref|ZP_07297211.1| phospholipase C [Streptomyces hy... 318 1e-84 gi|299139454|ref|ZP_07032629.1| Phospholipase C [Acidobacterium ... 316 6e-84 gi|295837178|ref|ZP_06824111.1| phospholipase C [Streptomyces sp... 315 8e-84 >gi|254551397|ref|ZP_05141844.1| phospholipase C 3 plcC [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|308370982|ref|ZP_07423454.2| phospholipase C 3 plcC [Mycobacterium tuberculosis SUMu003] gi|308373386|ref|ZP_07432124.2| phospholipase C 3 plcC [Mycobacterium tuberculosis SUMu005] gi|313659273|ref|ZP_07816153.1| phospholipase C 3 plcC [Mycobacterium tuberculosis KZN V2475] gi|18202462|sp|P95245.2|PHLC_MYCTU RecName: Full=Phospholipase C 3; Flags: Precursor gi|308330338|gb|EFP19189.1| phospholipase C 3 plcC [Mycobacterium tuberculosis SUMu003] gi|308337815|gb|EFP26666.1| phospholipase C 3 plcC [Mycobacterium tuberculosis SUMu005] Length=517 Score = 1039 bits (2687), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/508 (100%), Positives = 508/508 (100%), Gaps = 0/508 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF Sbjct 10 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 69 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI Sbjct 70 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 129 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL Sbjct 130 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 189 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL Sbjct 190 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 249 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT Sbjct 250 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 309 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP Sbjct 310 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 369 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR Sbjct 370 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 429 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE Sbjct 430 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 489 Query 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 GLPYRVPYPQTTPVQESGPARPIPSGIC Sbjct 490 GLPYRVPYPQTTPVQESGPARPIPSGIC 517 >gi|148823550|ref|YP_001288304.1| phospholipase C 3 plcC [Mycobacterium tuberculosis F11] gi|167969905|ref|ZP_02552182.1| phospholipase C 3 plcC [Mycobacterium tuberculosis H37Ra] gi|253798577|ref|YP_003031578.1| phospholipase C 3 plcC [Mycobacterium tuberculosis KZN 1435] 23 more sequence titles Length=516 Score = 1039 bits (2686), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/508 (100%), Positives = 508/508 (100%), Gaps = 0/508 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF Sbjct 9 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 68 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI Sbjct 69 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 128 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL Sbjct 129 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 188 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL Sbjct 189 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 248 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT Sbjct 249 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 308 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP Sbjct 309 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 368 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR Sbjct 369 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 428 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE Sbjct 429 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 488 Query 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 GLPYRVPYPQTTPVQESGPARPIPSGIC Sbjct 489 GLPYRVPYPQTTPVQESGPARPIPSGIC 516 >gi|15609486|ref|NP_216865.1| phospholipase C 3 PLCC [Mycobacterium tuberculosis H37Rv] gi|15841856|ref|NP_336893.1| phospholipase C [Mycobacterium tuberculosis CDC1551] gi|148662177|ref|YP_001283700.1| phospholipase C 3 PlcC [Mycobacterium tuberculosis H37Ra] 31 more sequence titles Length=508 Score = 1037 bits (2682), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/508 (100%), Positives = 508/508 (100%), Gaps = 0/508 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF Sbjct 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI Sbjct 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL Sbjct 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL Sbjct 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT Sbjct 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP Sbjct 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR Sbjct 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE Sbjct 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 Query 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 GLPYRVPYPQTTPVQESGPARPIPSGIC Sbjct 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 >gi|294994549|ref|ZP_06800240.1| phospholipase C 3 plcC [Mycobacterium tuberculosis 210] Length=517 Score = 1036 bits (2679), Expect = 0.0, Method: Compositional matrix adjust. Identities = 507/508 (99%), Positives = 507/508 (99%), Gaps = 0/508 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF Sbjct 10 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 69 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI Sbjct 70 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 129 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL Sbjct 130 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 189 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL Sbjct 190 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 249 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT Sbjct 250 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 309 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP Sbjct 310 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 369 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 EWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR Sbjct 370 CEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 429 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE Sbjct 430 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 489 Query 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 GLPYRVPYPQTTPVQESGPARPIPSGIC Sbjct 490 GLPYRVPYPQTTPVQESGPARPIPSGIC 517 >gi|289575041|ref|ZP_06455268.1| phospholipase C 3 plcC [Mycobacterium tuberculosis K85] gi|289539472|gb|EFD44050.1| phospholipase C 3 plcC [Mycobacterium tuberculosis K85] Length=508 Score = 1035 bits (2677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 507/508 (99%), Positives = 507/508 (99%), Gaps = 0/508 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF Sbjct 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRIN TGGPNGVGECVNDPDHQWI Sbjct 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINITGGPNGVGECVNDPDHQWI 120 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL Sbjct 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL Sbjct 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT Sbjct 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP Sbjct 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR Sbjct 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE Sbjct 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 Query 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 GLPYRVPYPQTTPVQESGPARPIPSGIC Sbjct 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 >gi|289758474|ref|ZP_06517852.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] gi|289714038|gb|EFD78050.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] gi|326903965|gb|EGE50898.1| phospholipase C 3 plcC [Mycobacterium tuberculosis W-148] gi|339295251|gb|AEJ47362.1| phospholipase C 3 plcC [Mycobacterium tuberculosis CCDC5079] gi|339298870|gb|AEJ50980.1| phospholipase C 3 plcC [Mycobacterium tuberculosis CCDC5180] Length=508 Score = 1034 bits (2673), Expect = 0.0, Method: Compositional matrix adjust. Identities = 507/508 (99%), Positives = 507/508 (99%), Gaps = 0/508 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF Sbjct 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI Sbjct 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL Sbjct 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL Sbjct 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT Sbjct 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP Sbjct 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 EWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR Sbjct 361 CEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE Sbjct 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 Query 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 GLPYRVPYPQTTPVQESGPARPIPSGIC Sbjct 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 >gi|240173290|ref|ZP_04751948.1| phospholipase C 3 plcC [Mycobacterium kansasii ATCC 12478] Length=538 Score = 925 bits (2390), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/508 (92%), Positives = 481/508 (95%), Gaps = 0/508 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR FLAKA GAGAAA LTDWAAPVIEKAY AGPCSGHLTDIEHIVLCLQENRSFDHYF Sbjct 31 MSRREFLAKATGAGAAAFLTDWAAPVIEKAYAAGPCSGHLTDIEHIVLCLQENRSFDHYF 90 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS+VDGFDTPTPLF QKGWNP+TQA+DP GITLPYRI+TT GPNGVGECVNDPDHQWI Sbjct 91 GTLSSVDGFDTPTPLFAQKGWNPQTQAVDPAGITLPYRIDTTRGPNGVGECVNDPDHQWI 150 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 AAHLSWNGGANDGWL AQARTRS ANTPVVMGYYARPDIPIHYLLADTFT+CD Y SSLL Sbjct 151 AAHLSWNGGANDGWLAAQARTRSAANTPVVMGYYARPDIPIHYLLADTFTVCDHYHSSLL 210 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GGTMPNRLYWIS TVNPDGDQGGPQIVEP+IQPKLTF+WRIMPQNLSDAGISWKVYNSKL Sbjct 211 GGTMPNRLYWISGTVNPDGDQGGPQIVEPSIQPKLTFSWRIMPQNLSDAGISWKVYNSKL 270 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LGGLNDTSLSRNGYVGSFK A DPRSDLARYGIAP YP DF+ DVINN LPQVSWVVPLT Sbjct 271 LGGLNDTSLSRNGYVGSFKAAGDPRSDLARYGIAPTYPMDFVLDVINNRLPQVSWVVPLT 330 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 V+SEHPSFP+AVGAVTIVNLIR LLRNPAVWEKTALIIAYDEHGGFFDHVTP TAP GTP Sbjct 331 VDSEHPSFPIAVGAVTIVNLIRTLLRNPAVWEKTALIIAYDEHGGFFDHVTPPTAPPGTP 390 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GEWIPNSVDI+KVDGSGGIRGPIGLG+RVPCFVISPYSRGGLMVHD+FDHTSQLQLIGKR Sbjct 391 GEWIPNSVDINKVDGSGGIRGPIGLGYRVPCFVISPYSRGGLMVHDQFDHTSQLQLIGKR 450 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 FGVPVPNLTPWRAS+TGDMTSAFNFAAPPDPS PNLDHP RQLPKVA CVPNVVLGFLNE Sbjct 451 FGVPVPNLTPWRASLTGDMTSAFNFAAPPDPSRPNLDHPARQLPKVANCVPNVVLGFLNE 510 Query 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 GLPYRVPYPQT PVQESGP R IPSGIC Sbjct 511 GLPYRVPYPQTMPVQESGPVRGIPSGIC 538 >gi|183983636|ref|YP_001851927.1| membrane-associated phospholipase C 2 PlcB_5 [Mycobacterium marinum M] gi|183176962|gb|ACC42072.1| membrane-associated phospholipase C 2 PlcB_5 [Mycobacterium marinum M] Length=516 Score = 912 bits (2356), Expect = 0.0, Method: Compositional matrix adjust. Identities = 446/508 (88%), Positives = 471/508 (93%), Gaps = 0/508 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR F+AKA G GA LTDWAAPVIEKAY AGPCSGHLTDIEHIVLCLQENRSFDHYF Sbjct 9 MSRREFMAKATGVGAGGFLTDWAAPVIEKAYAAGPCSGHLTDIEHIVLCLQENRSFDHYF 68 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 G+LS+VDGFDTPT LFQQKGW+P TQ++DP G T+PYRI+TT GPNGVGECVNDPDHQWI Sbjct 69 GSLSSVDGFDTPTSLFQQKGWDPRTQSVDPAGTTVPYRIDTTRGPNGVGECVNDPDHQWI 128 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 AAHLSWNGG NDGWL AQARTRS ANTPVVMGYYARPDIPIHYLLADTFTICDQY SSLL Sbjct 129 AAHLSWNGGGNDGWLAAQARTRSQANTPVVMGYYARPDIPIHYLLADTFTICDQYHSSLL 188 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GGTMPNRLYWIS TVNPDGD+GGPQIVEP IQPKLTF+WR+MP+NLSDAG+SWKVYNSKL Sbjct 189 GGTMPNRLYWISGTVNPDGDKGGPQIVEPTIQPKLTFSWRLMPENLSDAGVSWKVYNSKL 248 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LGGLNDTSLSRNGYVGSFKQA DPRSDLARYGIAP YP DF+ D++NN LPQVSWVVPLT Sbjct 249 LGGLNDTSLSRNGYVGSFKQAGDPRSDLARYGIAPRYPADFVLDIMNNRLPQVSWVVPLT 308 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 VESEHPSFPVAVGAVTIVNLIR LLRNPAVWEKTALIIAYDEHGGFFDHVTP T PEGTP Sbjct 309 VESEHPSFPVAVGAVTIVNLIRALLRNPAVWEKTALIIAYDEHGGFFDHVTPPTPPEGTP 368 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GEWIP +VDI+ VDGSGGIRGPIGLG+RVPCFVISPYSRGGL+ H+RFDHTSQLQLIGKR Sbjct 369 GEWIPPTVDINTVDGSGGIRGPIGLGYRVPCFVISPYSRGGLLAHERFDHTSQLQLIGKR 428 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNE 480 FGVPVPNLTPWRASVTGDMTSAFNFA PP+PSPPNLDHP +QLPK+ CVPN VLGFLNE Sbjct 429 FGVPVPNLTPWRASVTGDMTSAFNFAVPPNPSPPNLDHPAKQLPKLINCVPNAVLGFLNE 488 Query 481 GLPYRVPYPQTTPVQESGPARPIPSGIC 508 GLPYRVPYPQTTP QESGP R +PSGIC Sbjct 489 GLPYRVPYPQTTPTQESGPVRGVPSGIC 516 >gi|289750954|ref|ZP_06510332.1| phospholipase C 3 plcC [Mycobacterium tuberculosis T92] gi|289691541|gb|EFD58970.1| phospholipase C 3 plcC [Mycobacterium tuberculosis T92] Length=434 Score = 885 bits (2286), Expect = 0.0, Method: Compositional matrix adjust. Identities = 433/434 (99%), Positives = 434/434 (100%), Gaps = 0/434 (0%) Query 75 LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGW 134 +FQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGW Sbjct 1 MFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGW 60 Query 135 LPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISAT 194 LPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISAT Sbjct 61 LPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISAT 120 Query 195 VNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGY 254 VNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGY Sbjct 121 VNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGY 180 Query 255 VGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGA 314 VGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGA Sbjct 181 VGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGA 240 Query 315 VTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVD 374 VTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVD Sbjct 241 VTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVD 300 Query 375 GSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRAS 434 GSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRAS Sbjct 301 GSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRAS 360 Query 435 VTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNEGLPYRVPYPQTTPV 494 VTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNEGLPYRVPYPQTTPV Sbjct 361 VTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNVVLGFLNEGLPYRVPYPQTTPV 420 Query 495 QESGPARPIPSGIC 508 QESGPARPIPSGIC Sbjct 421 QESGPARPIPSGIC 434 >gi|240173292|ref|ZP_04751950.1| membrane-associated phospholipase C 2 PlcB_4 [Mycobacterium kansasii ATCC 12478] Length=511 Score = 709 bits (1829), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/512 (70%), Positives = 411/512 (81%), Gaps = 5/512 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR F AK GAGAAA+L D+A PVIEKAYGAGPCSGHLTDIEHIVL +QENRSFDHYF Sbjct 1 MSRREFFAKLTGAGAAALLMDFAGPVIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS+ GF+ P+P +QQKGWNP TQALDP GIT+P+R++TT GP GECVNDPDH WI Sbjct 61 GTLSSTRGFNDPSPAYQQKGWNPMTQALDPAGITIPFRLDTTRGPILDGECVNDPDHAWI 120 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 A H SWN G ND WLPAQ+ TR+ P+VMGYY R DIPIH+LLADTFTICD Y SLL Sbjct 121 AMHNSWNNGGNDNWLPAQSATRTGPYVPMVMGYYTRQDIPIHHLLADTFTICDGYHCSLL 180 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GGT+PNRLYW+SAT++P G GGPQ+VEP P+ ++WRIMP+NL DAGISWKVY SK Sbjct 181 GGTLPNRLYWMSATIDPAGTNGGPQLVEPGFLPEQQYSWRIMPENLEDAGISWKVYQSKD 240 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 G +T +S NG V +F+Q+A+PRS+LAR+GIAP YP DF DV N LPQVSW+VP Sbjct 241 AGRFINTPISNNGLVQAFRQSANPRSNLARFGIAPTYPLDFAADVKGNRLPQVSWLVPPF 300 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 ++SEHP+ PVA+GAV +VN +R+LL NPAVWEKTALII+YDE+GGFFDHVTP TAP GTP Sbjct 301 IQSEHPALPVALGAVAMVNALRILLSNPAVWEKTALIISYDENGGFFDHVTPPTAPPGTP 360 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GE++ DI+ V GSGGIRGPIGLGFRVPC VISP+SRGGLMVHD FDHTSQL+LI R Sbjct 361 GEYV-TVPDINAVTGSGGIRGPIGLGFRVPCLVISPFSRGGLMVHDTFDHTSQLKLIRAR 419 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLGFLN 479 FGVP+PNLT WR V GDMTSAFNFA PP+P+ PNL HP + +PK+ +C+PNVVLG + Sbjct 420 FGVPIPNLTAWRDGVVGDMTSAFNFATPPNPTRPNLSHPLLAAVPKLPQCIPNVVLGTTD 479 Query 480 EGL---PYRVPYPQTTPVQESGPARPIPSGIC 508 L PYRVPYPQ P QES P R IPSG+C Sbjct 480 GTLPAIPYRVPYPQIMPTQESSPTRGIPSGLC 511 >gi|289745624|ref|ZP_06505002.1| phospholipase C 2 [Mycobacterium tuberculosis 02_1987] gi|289686152|gb|EFD53640.1| phospholipase C 2 [Mycobacterium tuberculosis 02_1987] Length=520 Score = 702 bits (1811), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/513 (70%), Positives = 403/513 (79%), Gaps = 6/513 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR FL K GAGAAA L DWAAPVIEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 9 MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 68 Query 61 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 118 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 69 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 128 Query 119 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 129 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 188 Query 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 189 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 248 Query 238 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 297 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 249 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 308 Query 298 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 309 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 368 Query 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 GTPGE++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 369 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 427 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG Sbjct 428 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 487 Query 477 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 488 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 520 >gi|339298872|gb|AEJ50982.1| phospholipase C [Mycobacterium tuberculosis CCDC5180] Length=520 Score = 699 bits (1805), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/512 (69%), Positives = 406/512 (80%), Gaps = 5/512 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR FL K GAGAAA L DWAAPVIEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 9 MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 68 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS+ +GF+ +P FQQ GWNP TQALDP G+T+P+R++TT GP GECVNDP+HQW+ Sbjct 69 GTLSSTNGFNAASPAFQQMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQWV 128 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 HL+WNGGAND WLPAQA TR+ P+ MGYY R DIPIHYLLADTFTICD Y SLL Sbjct 129 GMHLAWNGGANDNWLPAQATTRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLL 188 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GT+PNRLYW+SA ++P G GGPQ+VEP P F+WRIMP+NL DAG+SWKVY +K Sbjct 189 TGTLPNRLYWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQNKG 248 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LG +T +S NG V +F+QAADPRS+LARYGIAP YP DF DV N LP+VSW+VP Sbjct 249 LGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLVPNI 308 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 ++SEHP+ PVA+GAV++V +R+LL NPAVWEKTALI++YDE+GGFFDHVTP TAP GTP Sbjct 309 LQSEHPALPVALGAVSMVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPPGTP 368 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GE++ +ID V GSGGIRGP+GLGFRVPC VISPYSRG LMV D FDHTSQL+LI R Sbjct 369 GEFV-TVPNIDAVPGSGGIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIRAR 427 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVR-QLPKVAKCVPNVVLGFLN 479 FGVPVPN+T WR V GDMTSAFNFAAPP+ + PNL HP+ LPK+ +C+PNVVLG + Sbjct 428 FGVPVPNMTAWRDGVVGDMTSAFNFAAPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTD 487 Query 480 EGL---PYRVPYPQTTPVQESGPARPIPSGIC 508 L PYRVPYPQ P QE+ P R PSG+C Sbjct 488 GALPSIPYRVPYPQVMPTQETTPVRGTPSGLC 519 >gi|308380173|ref|ZP_07669139.1| putative Tat (twin-arginine translocation) pathway signal sequence containing protein [Mycobacterium tuberculosis SUMu011] gi|339631808|ref|YP_004723450.1| phospholipase C [Mycobacterium africanum GM041182] gi|308362387|gb|EFP51238.1| putative Tat (twin-arginine translocation) pathway signal sequence containing protein [Mycobacterium tuberculosis SUMu011] gi|339331164|emb|CCC26844.1| putative phospholipase C 4 PLCD [Mycobacterium africanum GM041182] Length=525 Score = 699 bits (1803), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/509 (69%), Positives = 403/509 (80%), Gaps = 4/509 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 +SRR FLAK A GA A+++ +A PVIEKAYGAGPCSGHLTDIEH V +QENRSFDHYF Sbjct 20 VSRREFLAKVAAGGAGALMS-FAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYF 78 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS DGF+T +PLFQQKGWNP TQALD TG+T+PYR +TT GP G CVNDPDH W+ Sbjct 79 GTLSGTDGFNTVSPLFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHSWV 138 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 A H SWNGG ND WLPAQA+TRS A+TP VMGYY R DIPIHYLLAD FT+CD+YF S+L Sbjct 139 AMHESWNGGVNDNWLPAQAKTRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFCSVL 198 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 G T+PNRLYW+SAT++PDG GGP++ P QP F WRIMPQNLSDAG+SWKVY +K Sbjct 199 GPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYRNKT 258 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LG ++ L+ V SFKQ+ADPRSDL R+G+AP+YP F DV+ N LP+VSWV+P Sbjct 259 LGPISSV-LTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNV 317 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 +ESEHP+ P A GA IVN++R+LL NPAVWEKTALI++YDE+GGFFDHV P TAP GTP Sbjct 318 LESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTP 377 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GE++ DID+V GSGGIRGPIGLGFRVPCFVISPYSRG MVHD FDHTSQL+L+ R Sbjct 378 GEYV-TVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLETR 436 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLGFLN 479 FGVPVPNLT WR SVTGDMTS FNFA PP+ S PNLD+P + L V +CVPN LG +N Sbjct 437 FGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGTIN 496 Query 480 EGLPYRVPYPQTTPVQESGPARPIPSGIC 508 G+PYRVP PQ P QE+ P R IPSG C Sbjct 497 RGIPYRVPDPQIMPTQETTPTRGIPSGPC 525 >gi|289758476|ref|ZP_06517854.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] gi|294994547|ref|ZP_06800238.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis 210] gi|289714040|gb|EFD78052.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] gi|326903967|gb|EGE50900.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis W-148] Length=512 Score = 698 bits (1802), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/512 (69%), Positives = 406/512 (80%), Gaps = 5/512 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR FL K GAGAAA L DWAAPVIEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 1 MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS+ +GF+ +P FQQ GWNP TQALDP G+T+P+R++TT GP GECVNDP+HQW+ Sbjct 61 GTLSSTNGFNAASPAFQQMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQWV 120 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 HL+WNGGAND WLPAQA TR+ P+ MGYY R DIPIHYLLADTFTICD Y SLL Sbjct 121 GMHLAWNGGANDNWLPAQATTRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLL 180 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GT+PNRLYW+SA ++P G GGPQ+VEP P F+WRIMP+NL DAG+SWKVY +K Sbjct 181 TGTLPNRLYWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQNKG 240 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LG +T +S NG V +F+QAADPRS+LARYGIAP YP DF DV N LP+VSW+VP Sbjct 241 LGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLVPNI 300 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 ++SEHP+ PVA+GAV++V +R+LL NPAVWEKTALI++YDE+GGFFDHVTP TAP GTP Sbjct 301 LQSEHPALPVALGAVSMVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPPGTP 360 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GE++ +ID V GSGGIRGP+GLGFRVPC VISPYSRG LMV D FDHTSQL+LI R Sbjct 361 GEFV-TVPNIDAVPGSGGIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIRAR 419 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVR-QLPKVAKCVPNVVLGFLN 479 FGVPVPN+T WR V GDMTSAFNFAAPP+ + PNL HP+ LPK+ +C+PNVVLG + Sbjct 420 FGVPVPNMTAWRDGVVGDMTSAFNFAAPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTD 479 Query 480 EGL---PYRVPYPQTTPVQESGPARPIPSGIC 508 L PYRVPYPQ P QE+ P R PSG+C Sbjct 480 GALPSIPYRVPYPQVMPTQETTPVRGTPSGLC 511 >gi|15841221|ref|NP_336258.1| phospholipase C [Mycobacterium tuberculosis CDC1551] gi|31792943|ref|NP_855436.1| phospholipase C 4 PLCD [Mycobacterium bovis AF2122/97] gi|121637663|ref|YP_977886.1| putative phospholipase C 4 plcD [Mycobacterium bovis BCG str. Pasteur 1173P2] 28 more sequence titles Length=514 Score = 698 bits (1801), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/509 (69%), Positives = 403/509 (80%), Gaps = 4/509 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 +SRR FLAK A GA A+++ +A PVIEKAYGAGPCSGHLTDIEH V +QENRSFDHYF Sbjct 9 VSRREFLAKVAAGGAGALMS-FAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYF 67 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS DGF+T +PLFQQKGWNP TQALD TG+T+PYR +TT GP G CVNDPDH W+ Sbjct 68 GTLSGTDGFNTVSPLFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHSWV 127 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 A H SWNGG ND WLPAQA+TRS A+TP VMGYY R DIPIHYLLAD FT+CD+YF S+L Sbjct 128 AMHESWNGGVNDNWLPAQAKTRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFCSVL 187 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 G T+PNRLYW+SAT++PDG GGP++ P QP F WRIMPQNLSDAG+SWKVY +K Sbjct 188 GPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYRNKT 247 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LG ++ L+ V SFKQ+ADPRSDL R+G+AP+YP F DV+ N LP+VSWV+P Sbjct 248 LGPISSV-LTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNV 306 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 +ESEHP+ P A GA IVN++R+LL NPAVWEKTALI++YDE+GGFFDHV P TAP GTP Sbjct 307 LESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTP 366 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GE++ DID+V GSGGIRGPIGLGFRVPCFVISPYSRG MVHD FDHTSQL+L+ R Sbjct 367 GEYV-TVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLETR 425 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLGFLN 479 FGVPVPNLT WR SVTGDMTS FNFA PP+ S PNLD+P + L V +CVPN LG +N Sbjct 426 FGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGTIN 485 Query 480 EGLPYRVPYPQTTPVQESGPARPIPSGIC 508 G+PYRVP PQ P QE+ P R IPSG C Sbjct 486 RGIPYRVPDPQIMPTQETTPTRGIPSGPC 514 >gi|15841858|ref|NP_336895.1| phospholipase C [Mycobacterium tuberculosis CDC1551] gi|148823552|ref|YP_001288306.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis F11] gi|253798575|ref|YP_003031576.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis KZN 1435] 33 more sequence titles Length=520 Score = 697 bits (1800), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/512 (68%), Positives = 405/512 (80%), Gaps = 5/512 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR FL K GAGAAA L DWAAPVIEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 9 MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 68 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS+ +GF+ +P FQQ GWNP TQALDP G+T+P+R++TT GP GECVNDP+HQW+ Sbjct 69 GTLSSTNGFNAASPAFQQMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQWV 128 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 HL+WNGGAND WLPAQA TR+ P+ MGYY R DIPIHYLLADTFTICD Y SLL Sbjct 129 GMHLAWNGGANDNWLPAQATTRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLL 188 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GT+PNRLYW+SA ++P G GGPQ+VEP P F+WRIMP+NL DAG+SWKVY +K Sbjct 189 TGTLPNRLYWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQNKG 248 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LG +T +S NG V +F+QAADPRS+LARYGIAP YP DF DV N LP+VSW+VP Sbjct 249 LGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLVPNI 308 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 ++SEHP+ PVA+GAV++V +R+LL NPAVWEKTALI++YDE+GGFFDHVTP TAP GTP Sbjct 309 LQSEHPALPVALGAVSMVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPPGTP 368 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GE++ +ID V GSGGIRGP+GLGFRVPC VISPYSRG LMV D FDHTSQL+LI R Sbjct 369 GEFV-TVPNIDAVPGSGGIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIRAR 427 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVR-QLPKVAKCVPNVVLGFLN 479 FGVPVPN+T WR V GDMTSAFNFA PP+ + PNL HP+ LPK+ +C+PNVVLG + Sbjct 428 FGVPVPNMTAWRDGVVGDMTSAFNFATPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTD 487 Query 480 EGL---PYRVPYPQTTPVQESGPARPIPSGIC 508 L PYRVPYPQ P QE+ P R PSG+C Sbjct 488 GALPSIPYRVPYPQVMPTQETTPVRGTPSGLC 519 >gi|15609488|ref|NP_216867.1| membrane-associated phospholipase C [Mycobacterium tuberculosis H37Rv] gi|148662179|ref|YP_001283702.1| membrane-associated phospholipase C 1 [Mycobacterium tuberculosis H37Ra] gi|167969907|ref|ZP_02552184.1| membrane-associated phospholipase C 1 [Mycobacterium tuberculosis H37Ra] 18 more sequence titles Length=512 Score = 697 bits (1798), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/512 (68%), Positives = 405/512 (80%), Gaps = 5/512 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR FL K GAGAAA L DWAAPVIEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 1 MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS+ +GF+ +P FQQ GWNP TQALDP G+T+P+R++TT GP GECVNDP+HQW+ Sbjct 61 GTLSSTNGFNAASPAFQQMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQWV 120 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 HL+WNGGAND WLPAQA TR+ P+ MGYY R DIPIHYLLADTFTICD Y SLL Sbjct 121 GMHLAWNGGANDNWLPAQATTRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLL 180 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GT+PNRLYW+SA ++P G GGPQ+VEP P F+WRIMP+NL DAG+SWKVY +K Sbjct 181 TGTLPNRLYWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQNKG 240 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LG +T +S NG V +F+QAADPRS+LARYGIAP YP DF DV N LP+VSW+VP Sbjct 241 LGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLVPNI 300 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 ++SEHP+ PVA+GAV++V +R+LL NPAVWEKTALI++YDE+GGFFDHVTP TAP GTP Sbjct 301 LQSEHPALPVALGAVSMVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPPGTP 360 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GE++ +ID V GSGGIRGP+GLGFRVPC VISPYSRG LMV D FDHTSQL+LI R Sbjct 361 GEFV-TVPNIDAVPGSGGIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIRAR 419 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVR-QLPKVAKCVPNVVLGFLN 479 FGVPVPN+T WR V GDMTSAFNFA PP+ + PNL HP+ LPK+ +C+PNVVLG + Sbjct 420 FGVPVPNMTAWRDGVVGDMTSAFNFATPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTD 479 Query 480 EGL---PYRVPYPQTTPVQESGPARPIPSGIC 508 L PYRVPYPQ P QE+ P R PSG+C Sbjct 480 GALPSIPYRVPYPQVMPTQETTPVRGTPSGLC 511 >gi|183983637|ref|YP_001851928.1| membrane-associated phospholipase C 2 PlcB_4 [Mycobacterium marinum M] gi|183176963|gb|ACC42073.1| membrane-associated phospholipase C 2 PlcB_4 [Mycobacterium marinum M] Length=520 Score = 697 bits (1798), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/512 (69%), Positives = 406/512 (80%), Gaps = 5/512 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR F+AK GAGAAA+L D+A PVIEKAYGAGPCSG LTDIEHIVL +QENRSFDHYF Sbjct 9 MSRREFIAKMTGAGAAALLMDYAGPVIEKAYGAGPCSGQLTDIEHIVLLMQENRSFDHYF 68 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS++ GF P+P FQQKGWNP TQALDP G T+P+R++TT GP GECVNDP+HQW Sbjct 69 GTLSSIRGFSDPSPAFQQKGWNPRTQALDPAGTTIPFRLDTTRGPFLDGECVNDPEHQWT 128 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 A HLSWNGGAND WLPAQA TR+ P+ MGYY R DIPIH+LLADTFTICD Y SLL Sbjct 129 AMHLSWNGGANDNWLPAQANTRTGPYVPMTMGYYTRQDIPIHHLLADTFTICDGYHCSLL 188 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 GT+PNRLYW+SA +P G GGPQ+VEP P ++WRIMP+NL DAG+SWKVY +K Sbjct 189 TGTLPNRLYWMSAWNDPAGTNGGPQLVEPGFLPLHQYSWRIMPENLEDAGVSWKVYQNKD 248 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 G +T +S NG V +FKQ+ DPRS+LARYGIAP YP DF DV N LP+VSW+VP Sbjct 249 AGRFINTPISNNGLVQAFKQSGDPRSNLARYGIAPGYPVDFAADVKANRLPKVSWLVPNF 308 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 ++SEHP+ PVA+GAV +V +R+LL NPAVWEKTALII+YDE+GGFFDHVTP TAP GTP Sbjct 309 LQSEHPALPVALGAVAMVTALRILLSNPAVWEKTALIISYDENGGFFDHVTPPTAPPGTP 368 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GEW+ DI+ V GSGGIRGP+GLGFRVPC V+SP+SRGGLMVHD FDHTSQL+LI KR Sbjct 369 GEWV-TVPDINSVPGSGGIRGPLGLGFRVPCIVVSPFSRGGLMVHDIFDHTSQLKLISKR 427 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLGFLN 479 F VPVPNLT WR V GDMTS FNFA PP+PS PNL HP + +PK+ +C+PNVVLG + Sbjct 428 FDVPVPNLTAWRDGVVGDMTSTFNFATPPNPSRPNLSHPLLAAVPKLPQCIPNVVLGTSD 487 Query 480 ---EGLPYRVPYPQTTPVQESGPARPIPSGIC 508 +PYRVPYPQ+ P QES P R +PSG+C Sbjct 488 GTFPAIPYRVPYPQSMPGQESTPVRGVPSGLC 519 >gi|254231948|ref|ZP_04925275.1| phospholipase C 4 (fragment) plcD [Mycobacterium tuberculosis C] gi|124601007|gb|EAY60017.1| phospholipase C 4 (fragment) plcD [Mycobacterium tuberculosis C] Length=488 Score = 687 bits (1774), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/488 (70%), Positives = 388/488 (80%), Gaps = 3/488 (0%) Query 22 WAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYFGTLSAVDGFDTPTPLFQQKGW 81 +A PVIEKAYGAGPCSGHLTDIEH V +QENRSFDHYFGTLS DGF+T +PLFQQKGW Sbjct 3 FAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYFGTLSGTDGFNTVSPLFQQKGW 62 Query 82 NPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGWLPAQART 141 NP TQALD TG+T+PYR +TT GP G CVNDPDH W+A H SWNGG ND WLPAQA+T Sbjct 63 NPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHSWVAMHESWNGGVNDNWLPAQAKT 122 Query 142 RSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISATVNPDGDQ 201 RS A+TP VMGYY R DIPIHYLLAD FT+CD+YF S+LG T+PNRLYW+SAT++PDG Sbjct 123 RSAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNRLYWLSATIDPDGQN 182 Query 202 GGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKQA 261 GGP++ P QP F WRIMPQNLSDAG+SWKVY +K LG ++ L+ V SFKQ+ Sbjct 183 GGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYRNKTLGPISSV-LTYGSLVTSFKQS 241 Query 262 ADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGAVTIVNLI 321 ADPRSDL R+G+AP+YP F DV+ N LP+VSWV+P +ESEHP+ P A GA IVN++ Sbjct 242 ADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNVLESEHPAVPAAAGAFAIVNIL 301 Query 322 RVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVDGSGGIRG 381 R+LL NPAVWEKTALI++YDE+GGFFDHV P TAP GTPGE++ DID+V GSGGIRG Sbjct 302 RILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTPGEYV-TVPDIDQVPGSGGIRG 360 Query 382 PIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRASVTGDMTS 441 PIGLGFRVPCFVISPYSRG MVHD FDHTSQL+L+ RFGVPVPNLT WR SVTGDMTS Sbjct 361 PIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTS 420 Query 442 AFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLGFLNEGLPYRVPYPQTTPVQESGPA 500 FNFA PP+ S PNLD+P + L V +CVPN LG +N G+PYRVP PQ P QE+ P Sbjct 421 TFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGTINRGIPYRVPDPQIMPTQETTPT 480 Query 501 RPIPSGIC 508 R IPSG C Sbjct 481 RGIPSGPC 488 >gi|217069518|gb|ACJ83246.1| Rv2349c antigen [Mycobacterium tuberculosis] Length=338 Score = 687 bits (1773), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/338 (100%), Positives = 338/338 (100%), Gaps = 0/338 (0%) Query 171 ICDQYFSSLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAG 230 ICDQYFSSLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAG Sbjct 1 ICDQYFSSLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAG 60 Query 231 ISWKVYNSKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTL 290 ISWKVYNSKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTL Sbjct 61 ISWKVYNSKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTL 120 Query 291 PQVSWVVPLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHV 350 PQVSWVVPLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHV Sbjct 121 PQVSWVVPLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHV 180 Query 351 TPLTAPEGTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDH 410 TPLTAPEGTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDH Sbjct 181 TPLTAPEGTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDH 240 Query 411 TSQLQLIGKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCV 470 TSQLQLIGKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCV Sbjct 241 TSQLQLIGKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCV 300 Query 471 PNVVLGFLNEGLPYRVPYPQTTPVQESGPARPIPSGIC 508 PNVVLGFLNEGLPYRVPYPQTTPVQESGPARPIPSGIC Sbjct 301 PNVVLGFLNEGLPYRVPYPQTTPVQESGPARPIPSGIC 338 >gi|183983547|ref|YP_001851838.1| membrane-associated phospholipase C 2 PlcB [Mycobacterium marinum M] gi|183176873|gb|ACC41983.1| membrane-associated phospholipase C 2 PlcB [Mycobacterium marinum M] Length=521 Score = 686 bits (1770), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/512 (67%), Positives = 401/512 (79%), Gaps = 5/512 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR F+AK A A +A + A PVIEKAYGAGPCSGHLTDIEH V LQENRSFDHYF Sbjct 11 MSRREFMAKLAAASSAGAMMSLAGPVIEKAYGAGPCSGHLTDIEHFVFMLQENRSFDHYF 70 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 G+LS ++GFDTP+ FQQKGWNP+TQ++DP G+T+PYR +TT GP G CVNDP HQWI Sbjct 71 GSLSGINGFDTPSSAFQQKGWNPQTQSIDPAGVTIPYRFDTTRGPLLNGACVNDPGHQWI 130 Query 121 AAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSL 179 H ++N GAND WL AQA+ +++ N PV MGYY R D PIHYLLADTFTICD Y SL Sbjct 131 DMHRAFNNGANDNWLGAQAQAQTLQGNVPVTMGYYTRQDQPIHYLLADTFTICDGYHCSL 190 Query 180 LGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSK 239 +GGT PNRLYW+SA ++P+G+QGGP +V+P IQP+ F+WR MP NLSDAGISWKVY +K Sbjct 191 IGGTSPNRLYWMSAWIDPNGEQGGPLLVDPNIQPQGRFSWRTMPDNLSDAGISWKVYQNK 250 Query 240 LLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPL 299 LLG LN+T + +G + F QA DPRS++ARYGIAP YP DF+ DV +N LPQVSWV+P Sbjct 251 LLGALNNTVIGYDGMLNDFVQARDPRSNMARYGIAPTYPLDFVADVASNRLPQVSWVLPG 310 Query 300 TVESEHPSFPV--AVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 SEHP PV AVG IVN++R+LL NPAVWEKTALI+++DE+GGFFDHVTP TAPE Sbjct 311 FQVSEHPGVPVAPAVGGTAIVNILRILLSNPAVWEKTALIVSFDENGGFFDHVTPTTAPE 370 Query 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 GTPGEWI DI+ V GSGGIRGPIGLG+RVPCFVISPYSRG LMVHD FDHTSQL+L+ Sbjct 371 GTPGEWI-TVPDINAVTGSGGIRGPIGLGYRVPCFVISPYSRGPLMVHDIFDHTSQLRLL 429 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 +RFGVPVPNLT WR VTGDMTS FNFA PP+ SPPNLDHP ++ +P+ +CVP+ V Sbjct 430 EQRFGVPVPNLTTWRRGVTGDMTSTFNFAVPPNASPPNLDHPALKAVPQQVQCVPDTVTV 489 Query 477 FLNEGLPYRVPYPQTTPVQESGPARPIPSGIC 508 F PYRVP+PQ P QE+ P R IPSG C Sbjct 490 FTKTVPPYRVPFPQVMPSQETSPTRGIPSGPC 521 >gi|118618235|ref|YP_906567.1| membrane-associated phospholipase C 2 PlcB [Mycobacterium ulcerans Agy99] gi|118570345|gb|ABL05096.1| membrane-associated phospholipase C 2 PlcB [Mycobacterium ulcerans Agy99] Length=511 Score = 685 bits (1768), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/512 (67%), Positives = 400/512 (79%), Gaps = 5/512 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR F+AK A A +A + A PVIEKAYGAGPCSGHLTDIEH V LQENRSFDHYF Sbjct 1 MSRREFMAKLAAASSAGAMMSLAGPVIEKAYGAGPCSGHLTDIEHFVFMLQENRSFDHYF 60 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 G+LS ++GFDTP+ FQQKGWNP+TQ++DP G+T+PYR +TT GP G C NDP HQWI Sbjct 61 GSLSGINGFDTPSSAFQQKGWNPQTQSIDPAGVTIPYRFDTTRGPLLNGACANDPGHQWI 120 Query 121 AAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSL 179 H ++N GAND WL AQA+ +++ N PV MGYY R D PIHYLLADTFTICD Y SL Sbjct 121 DMHRAFNNGANDNWLGAQAQAQTLQGNVPVTMGYYTRQDQPIHYLLADTFTICDGYHCSL 180 Query 180 LGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSK 239 +GGT PNRLYW+SA V+P+G+QGGP +V+P IQP+ F+WR MP NLSDAGISWKVY +K Sbjct 181 IGGTSPNRLYWMSAWVDPNGEQGGPLLVDPNIQPQGRFSWRTMPDNLSDAGISWKVYQNK 240 Query 240 LLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPL 299 LLG LN+T + +G + F QA DPRS++ARYGIAP YP DF+ DV +N LPQVSWV+P Sbjct 241 LLGALNNTVIGYDGMLNDFVQARDPRSNMARYGIAPTYPLDFVADVASNRLPQVSWVLPG 300 Query 300 TVESEHPSFPV--AVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 SEHP PV AVG IVN++R+LL NPAVWEKTALI+++DE+GGFFDHVTP TAPE Sbjct 301 FQVSEHPGVPVAPAVGGTAIVNILRILLSNPAVWEKTALIVSFDENGGFFDHVTPTTAPE 360 Query 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 GTPGEWI DI+ V GSGGIRGPIGLG+RVPCFVISPYSRG LMVHD FDHTSQL+L+ Sbjct 361 GTPGEWI-TVPDINAVTGSGGIRGPIGLGYRVPCFVISPYSRGPLMVHDIFDHTSQLRLL 419 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 +RFGVPVPNLT WR VTGDMTS FNFA PP+ SPPNLDHP ++ +P+ +CVP+ V Sbjct 420 EQRFGVPVPNLTTWRRGVTGDMTSTFNFAVPPNASPPNLDHPALKAVPQQVQCVPDTVTV 479 Query 477 FLNEGLPYRVPYPQTTPVQESGPARPIPSGIC 508 F PYRVP+PQ P QE+ P R IPSG C Sbjct 480 FTKTVPPYRVPFPQVMPSQETSPTRGIPSGPC 511 >gi|240170410|ref|ZP_04749069.1| membrane-associated phospholipase C 2 PlcB_6 [Mycobacterium kansasii ATCC 12478] Length=517 Score = 682 bits (1759), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/510 (68%), Positives = 391/510 (77%), Gaps = 3/510 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 M+RR FLAKAA A AA L PVIEKAYGAGPCSG LTDIEHIVL +QENRSFDHYF Sbjct 9 MTRREFLAKAAAATTAASLMSLVGPVIEKAYGAGPCSGQLTDIEHIVLLMQENRSFDHYF 68 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS +DGFDT +PLFQQKGW+P TQ+LDP+GITLP+R +TT P G C+NDPDH WI Sbjct 69 GTLSDIDGFDTASPLFQQKGWDPRTQSLDPSGITLPFRFDTTRAPFLNGACINDPDHDWI 128 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 A H SWNGGAND WLPAQARTRS ANTP MGY+ R DIPIHYLLADTFT+CD YF S+L Sbjct 129 AIHQSWNGGANDNWLPAQARTRSAANTPATMGYHTRRDIPIHYLLADTFTVCDHYFCSVL 188 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 G T PNRLYW+SA ++P G GGP + + P F WRIMPQNLSDAG+SWKVY+ K Sbjct 189 GPTSPNRLYWLSAWIDPAGTNGGPLVETSSTAPIGAFNWRIMPQNLSDAGVSWKVYSDKS 248 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LG + + V FKQAADPRSDLAR+G+AP YPWDF DV N LPQVSW+VP Sbjct 249 LGPAVNAYVGYGEIVRWFKQAADPRSDLARFGVAPRYPWDFAADVRANRLPQVSWLVPNI 308 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 + SEHP+ P A GAV + + +R+LL NPAVWEKTALI++YDE+GGFFDHV P TAP GT Sbjct 309 LVSEHPAMPDAGGAVAMADTLRILLSNPAVWEKTALIVSYDENGGFFDHVVPPTAPPGTA 368 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GE++ DID V GSGGIRGPIGLGFRVPC VISP+SRGGLM HD FDHTSQL+LI KR Sbjct 369 GEYL-TVPDIDGVAGSGGIRGPIGLGFRVPCLVISPFSRGGLMAHDVFDHTSQLRLIEKR 427 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNV--VLGFL 478 FGVPVPNLT WR SVTGDMTSAFNFA PP+PSPP L+ R LP++A+C + + G Sbjct 428 FGVPVPNLTAWRRSVTGDMTSAFNFAVPPNPSPPKLNQSRRVLPELAQCGLGIGALTGTY 487 Query 479 NEGLPYRVPYPQTTPVQESGPARPIPSGIC 508 PYRVPYPQ P QE+ P R IPSG+C Sbjct 488 RLNPPYRVPYPQAMPSQETTPTRGIPSGLC 517 >gi|240173291|ref|ZP_04751949.1| membrane-associated phospholipase C 2 [Mycobacterium kansasii ATCC 12478] Length=510 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/511 (68%), Positives = 402/511 (79%), Gaps = 4/511 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 M+RR F AKAA A A LT AAP+IEKAYGAGPCSGHLTDIEHIVL +QENRSFDHYF Sbjct 1 MTRRQFFAKAAAATTAGALTSLAAPIIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS GF+ P+P F QKGWNP TQA+DP G T+P+R +TT GP GECVNDPDH WI Sbjct 61 GTLSGTRGFNDPSPAFAQKGWNPATQAVDPAGTTIPFRFDTTRGPLLDGECVNDPDHGWI 120 Query 121 AAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSL 179 A H SWNGGANDGWLPAQA + + N PV MGYY R D+PIHYLLADTFT+CD Y+ SL Sbjct 121 AMHNSWNGGANDGWLPAQAASSPLQGNVPVTMGYYTRRDLPIHYLLADTFTVCDAYYCSL 180 Query 180 LGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSK 239 LGGT PNRLYW+SA ++PDG GGP ++EP IQP+ +WRIMPQNL DA +SWKVY +K Sbjct 181 LGGTTPNRLYWMSAWIDPDGTNGGPILIEPNIQPQQKLSWRIMPQNLEDAAVSWKVYQNK 240 Query 240 LLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPL 299 LG LN+T + NG + F+QAADPRS+LARYGIAP YP DF DV NN LP+VSWV+P Sbjct 241 FLGPLNNTVVGYNGLINDFQQAADPRSNLARYGIAPTYPLDFAADVKNNALPKVSWVLPG 300 Query 300 TVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGT 359 + SEHP+ PV++GAV IV+++R+LL NPAVWEKTA+I+ YDE+GGFFDHVTP T P GT Sbjct 301 FLLSEHPALPVSIGAVGIVDVLRILLSNPAVWEKTAVIVNYDENGGFFDHVTPPTPPPGT 360 Query 360 PGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGK 419 PGE++ DI+ V GSGGIRGPIGLGFR PC VISPYSRG LMVHD FDHTS L+LI Sbjct 361 PGEYV-TVPDINAVPGSGGIRGPIGLGFRTPCIVISPYSRGPLMVHDTFDHTSTLKLISA 419 Query 420 RFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLGFL 478 RFGVPVPNL+ WR V GDMTS FNFA PP+PS PNLDHP ++ +PK+ +CVPN VLG Sbjct 420 RFGVPVPNLSAWRNGVVGDMTSTFNFAVPPNPSKPNLDHPLLKSVPKLPQCVPNAVLGTT 479 Query 479 NE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 + +PYRVP+PQ P QE+ P R IPSG+C Sbjct 480 TKTSIPYRVPFPQMMPTQETSPTRGIPSGVC 510 >gi|183983797|ref|YP_001852088.1| membrane-associated phospholipase C 2 PlcB_1 [Mycobacterium marinum M] gi|183177123|gb|ACC42233.1| membrane-associated phospholipase C 2 PlcB_1 [Mycobacterium marinum M] Length=518 Score = 677 bits (1746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/513 (68%), Positives = 402/513 (79%), Gaps = 8/513 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR FLAKAA A A A PVIEKAY AGPCSGHL+DIEHIVL +QENRSFDHYF Sbjct 9 MSRREFLAKAAAASGAGAFMSLAGPVIEKAYAAGPCSGHLSDIEHIVLFMQENRSFDHYF 68 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 G LS +GFD+ +PLF QKGWNP+TQ+ DP G T+PYR +TT GP GECVNDP H WI Sbjct 69 GKLSGTNGFDSGSPLFAQKGWNPQTQSNDPAGTTIPYRFDTTRGPLVAGECVNDPGHDWI 128 Query 121 AAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSL 179 A H +WN G ND WLPAQA ++ NTPV MGYY R DIPIHYLLADTFTICD YF SL Sbjct 129 AMHNAWNNGGNDNWLPAQAAVSALQGNTPVTMGYYQREDIPIHYLLADTFTICDGYFCSL 188 Query 180 LGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSK 239 +GGT PNRLYW+S T++PDG GGP +V+P IQP+ F+WR MP NL DAG+SWK+Y +K Sbjct 189 IGGTSPNRLYWMSGTIDPDGANGGPLLVDPNIQPQGRFSWRTMPDNLEDAGVSWKIYQNK 248 Query 240 LLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPL 299 LLG LN+T + +G + FKQA +PR++LARYGIAP YP DF+ DV NN LP+VSWV+P Sbjct 249 LLGALNNTVIGYDGMLNDFKQAQNPRTNLARYGIAPTYPRDFVSDVRNNRLPKVSWVLPG 308 Query 300 TVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGT 359 + SEHP+FPV VGAV IV+++R+LL NPAVWEKTALI++YDE+GGFFDHVTP TAP GT Sbjct 309 FLLSEHPAFPVNVGAVAIVDVLRILLSNPAVWEKTALIVSYDENGGFFDHVTPTTAPPGT 368 Query 360 PGEWI--PNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 PGEWI PN ID V GSGGIRGPIGLG+RVPCFVISPYSRG LMVHD FDHTSQL+LI Sbjct 369 PGEWITVPN---IDAVTGSGGIRGPIGLGYRVPCFVISPYSRGPLMVHDTFDHTSQLKLI 425 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 RFGVPVPN++ WR + GDMTS FNFA PP+ S PNL HP + + K+ +CVPN VLG Sbjct 426 ETRFGVPVPNISAWRNGLVGDMTSTFNFAVPPNSSRPNLSHPAINAVQKLPQCVPNYVLG 485 Query 477 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 + + +PYRVP+PQ P QE+ PAR IPSG+C Sbjct 486 TVTKTAVPYRVPFPQVMPTQETQPARGIPSGLC 518 >gi|183981500|ref|YP_001849791.1| membrane-associated phospholipase C 2 PlcB_2 [Mycobacterium marinum M] gi|183174826|gb|ACC39936.1| membrane-associated phospholipase C 2 PlcB_2 [Mycobacterium marinum M] Length=528 Score = 673 bits (1736), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/524 (66%), Positives = 405/524 (78%), Gaps = 18/524 (3%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR FLAKAA GA A+++ +A PVIEKAYGAGPCSGHL+DIEH V L ENRSFDHYF Sbjct 7 MSRRKFLAKAAAGGAGALMS-FAGPVIEKAYGAGPCSGHLSDIEHFVFFLMENRSFDHYF 65 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLSA DGFD+ +PLFQQKGWNP+TQ +DP GIT+PYR +TT GP GEC++DPDH W Sbjct 66 GTLSATDGFDSGSPLFQQKGWNPQTQTIDPAGITMPYRFDTTRGPFVDGECLSDPDHSWE 125 Query 121 AAHLSWNGGANDGWLPAQARTRSV---ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 A H SWNGGAND WLPAQ V N PV MGY R DIPIHYLLADTFT+CD+YFS Sbjct 126 AMHKSWNGGANDNWLPAQVGHSPVPNGGNVPVTMGYLTRKDIPIHYLLADTFTVCDRYFS 185 Query 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 S+LG T+PNRLYW+SA++ DG QGGPQ+ P P F+W MP+NLS AGISWK+Y Sbjct 186 SVLGPTLPNRLYWLSASLGADGTQGGPQLTSPPTDPIGRFSWTTMPENLSAAGISWKLYR 245 Query 238 SKLLGGLNDT--SLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSW 295 +K LG + + + + + V FKQA DPRS+LAR+G+AP YP++F+ DV N LPQVSW Sbjct 246 NKTLGPVLNQYFNYTYDDIVMFFKQAQDPRSELARFGMAPTYPFEFMADVKANRLPQVSW 305 Query 296 VVPLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTA 355 VVP T +SEHP+FP AVGAV IVNL+R+LL NPAVWEKTALI+ YDE+GGFFDHV P TA Sbjct 306 VVPNTPQSEHPAFPPAVGAVAIVNLLRILLSNPAVWEKTALIVGYDENGGFFDHVVPPTA 365 Query 356 PEGTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQ 415 PEGTPGE++ DI+ V G+GGIRGPIGLG+RVP VISP+SRGGLMVHD FDHTSQL+ Sbjct 366 PEGTPGEYL-TVPDINSVSGAGGIRGPIGLGYRVPGIVISPFSRGGLMVHDVFDHTSQLK 424 Query 416 LIGKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVV 474 LI KRF VPVPNLTPWR S GDMTSAFNFA PP+PS P+L HP + LPK+ +C+PNV Sbjct 425 LISKRFSVPVPNLTPWRDSTVGDMTSAFNFAVPPNPSRPSLSHPGLAALPKLPQCIPNVW 484 Query 475 LGFLN----------EGLPYRVPYPQTTPVQESGPARPIPSGIC 508 LG + +G+PYRVP+PQ+ P QE+ PAR IPSG C Sbjct 485 LGTVGVNPNPYTGSPQGIPYRVPFPQSLPSQETTPARGIPSGPC 528 >gi|240169308|ref|ZP_04747967.1| membrane-associated phospholipase C 2 PlcB [Mycobacterium kansasii ATCC 12478] Length=511 Score = 672 bits (1734), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/512 (68%), Positives = 401/512 (79%), Gaps = 5/512 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR F+A+ A AG+A L A PVIE+AYGAGPCSGHLTDIEH VL LQENRSFDH+F Sbjct 1 MSRREFMARIATAGSAGALMSLAGPVIERAYGAGPCSGHLTDIEHFVLMLQENRSFDHFF 60 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS ++GFDTP+P FQQKGWNP+TQ++DP G+T+PYR +TT GP G CVNDP HQWI Sbjct 61 GTLSGINGFDTPSPSFQQKGWNPQTQSIDPAGVTIPYRFDTTRGPVLNGACVNDPAHQWI 120 Query 121 AAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSL 179 H SWN GAND WLPAQA +++ N PV MGYY R D PIHYLLADTFTICD Y+ SL Sbjct 121 TIHKSWNNGANDNWLPAQAEQQTLQGNVPVSMGYYTRQDQPIHYLLADTFTICDGYYCSL 180 Query 180 LGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSK 239 LGGT PNRLYWISA ++PDG GGP +++P IQP+ F+WR MP NLSDAGISWKVY +K Sbjct 181 LGGTSPNRLYWISAWIDPDGVAGGPLLIDPNIQPQAQFSWRTMPDNLSDAGISWKVYQNK 240 Query 240 LLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPL 299 LLG LN+T + NG + FKQA DPRS++AR GIAP YP DF+ DV N LPQVSWV+P Sbjct 241 LLGALNNTVIGYNGMLVDFKQAQDPRSNIARNGIAPTYPLDFVADVAANRLPQVSWVLPG 300 Query 300 TVESEHPSFPV--AVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 SEHP PV AVG IVN++R+LL NP VWEKTALI+++DE+GGFFDHVTP TAP Sbjct 301 FQVSEHPGLPVTPAVGGTAIVNILRILLSNPQVWEKTALIVSFDENGGFFDHVTPPTAPP 360 Query 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 GTPGE++ DID V GSGGIRGPIGLG+RVPCF+ISPYSRG LMVHD FDHTSQL+L+ Sbjct 361 GTPGEYV-TVPDIDAVTGSGGIRGPIGLGYRVPCFIISPYSRGPLMVHDTFDHTSQLRLL 419 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQ-LPKVAKCVPNVVLG 476 KRFGVPVPNL+ WR SVTGDMTS FNFA PP+P+PPNLDHP Q +P +CVP+ V Sbjct 420 EKRFGVPVPNLSAWRRSVTGDMTSTFNFAVPPNPAPPNLDHPALQAIPPQVQCVPDTVAT 479 Query 477 FLNEGLPYRVPYPQTTPVQESGPARPIPSGIC 508 F PYRVP+PQ P QE+ PAR IPSG C Sbjct 480 FAKVTPPYRVPFPQVMPTQETTPARGIPSGPC 511 >gi|339295253|gb|AEJ47364.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis CCDC5079] Length=493 Score = 672 bits (1733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/492 (69%), Positives = 392/492 (80%), Gaps = 5/492 (1%) Query 21 DWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYFGTLSAVDGFDTPTPLFQQKG 80 DWAAPVIEKAYGAGPC GHLTDIEHIVL +QENRSFDHYFGTLS+ +GF+ +P FQQ G Sbjct 2 DWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYFGTLSSTNGFNAASPAFQQMG 61 Query 81 WNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGWLPAQAR 140 WNP TQALDP G+T+P+R++TT GP GECVNDP+HQW+ HL+WNGGAND WLPAQA Sbjct 62 WNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQWVGMHLAWNGGANDNWLPAQAT 121 Query 141 TRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISATVNPDGD 200 TR+ P+ MGYY R DIPIHYLLADTFTICD Y SLL GT+PNRLYW+SA ++P G Sbjct 122 TRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLLTGTLPNRLYWLSANIDPAGT 181 Query 201 QGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKQ 260 GGPQ+VEP P F+WRIMP+NL DAG+SWKVY +K LG +T +S NG V +F+Q Sbjct 182 DGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQNKGLGRFINTPISNNGLVQAFRQ 241 Query 261 AADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGAVTIVNL 320 AADPRS+LARYGIAP YP DF DV N LP+VSW+VP ++SEHP+ PVA+GAV++V Sbjct 242 AADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLVPNILQSEHPALPVALGAVSMVTA 301 Query 321 IRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVDGSGGIR 380 +R+LL NPAVWEKTALI++YDE+GGFFDHVTP TAP GTPGE++ +ID V GSGGIR Sbjct 302 LRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPPGTPGEFV-TVPNIDAVPGSGGIR 360 Query 381 GPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRASVTGDMT 440 GP+GLGFRVPC VISPYSRG LMV D FDHTSQL+LI RFGVPVPN+T WR V GDMT Sbjct 361 GPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIRARFGVPVPNMTAWRDGVVGDMT 420 Query 441 SAFNFAAPPDPSPPNLDHPVR-QLPKVAKCVPNVVLGFLNEGL---PYRVPYPQTTPVQE 496 SAFNFAAPP+ + PNL HP+ LPK+ +C+PNVVLG + L PYRVPYPQ P QE Sbjct 421 SAFNFAAPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTDGALPSIPYRVPYPQVMPTQE 480 Query 497 SGPARPIPSGIC 508 + P R PSG+C Sbjct 481 TTPVRGTPSGLC 492 >gi|15609487|ref|NP_216866.1| membrane-associated phospholipase C [Mycobacterium tuberculosis H37Rv] gi|15841857|ref|NP_336894.1| phospholipase C [Mycobacterium tuberculosis CDC1551] gi|148662178|ref|YP_001283701.1| membrane-associated phospholipase C 2 [Mycobacterium tuberculosis H37Ra] 36 more sequence titles Length=512 Score = 670 bits (1729), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/513 (68%), Positives = 397/513 (78%), Gaps = 6/513 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 118 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 Query 119 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 Query 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 Query 238 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 297 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 Query 298 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 Query 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 GTPGE++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 361 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG Sbjct 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 479 Query 477 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 >gi|148823551|ref|YP_001288305.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis F11] gi|253798576|ref|YP_003031577.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis KZN 1435] gi|289553863|ref|ZP_06443073.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis KZN 605] 9 more sequence titles Length=521 Score = 670 bits (1728), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/513 (68%), Positives = 397/513 (78%), Gaps = 6/513 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 10 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 69 Query 61 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 118 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 70 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 129 Query 119 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 130 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 189 Query 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 190 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 249 Query 238 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 297 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 250 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 309 Query 298 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 310 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 369 Query 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 GTPGE++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 370 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 428 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG Sbjct 429 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 488 Query 477 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 489 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 521 >gi|306780388|ref|ZP_07418725.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu002] gi|306968494|ref|ZP_07481155.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu009] gi|308326820|gb|EFP15671.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu002] gi|308353918|gb|EFP42769.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu009] Length=512 Score = 669 bits (1726), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/513 (68%), Positives = 396/513 (78%), Gaps = 6/513 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 118 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 Query 119 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 Query 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 Query 238 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 297 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 Query 298 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 Query 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 GTPGE++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 361 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK +CVPN VLG Sbjct 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKSPQCVPNAVLG 479 Query 477 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 >gi|308370983|ref|ZP_07423455.2| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu003] gi|308372210|ref|ZP_07427820.2| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu004] gi|308373387|ref|ZP_07432125.2| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu005] 9 more sequence titles Length=521 Score = 669 bits (1726), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/513 (68%), Positives = 396/513 (78%), Gaps = 6/513 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 10 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 69 Query 61 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 118 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 70 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 129 Query 119 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 130 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 189 Query 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 190 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 249 Query 238 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 297 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 250 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 309 Query 298 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 310 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 369 Query 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 GTPGE++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 370 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 428 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK +CVPN VLG Sbjct 429 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKSPQCVPNAVLG 488 Query 477 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 489 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 521 >gi|1399494|gb|AAC18944.1| phospholipase C [Mycobacterium tuberculosis H37Rv] Length=521 Score = 649 bits (1675), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/514 (67%), Positives = 392/514 (77%), Gaps = 8/514 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 10 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 69 Query 61 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 118 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 70 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 129 Query 119 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 130 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 189 Query 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 190 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 249 Query 238 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 297 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN L +VSWV+ Sbjct 250 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLTKVSWVL 309 Query 298 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 310 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 369 Query 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 GTPGE++ DID V GSGGIRG IGLG RVPC ISPY+ G LMVHD FDHTS L+LI Sbjct 370 GTPGEFV-TVPDIDSVPGSGGIRGAIGLGPRVPCLFISPYT-GPLMVHDTFDHTSTLKLI 427 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQ--LPKVAKCVPNVVL 475 RFGVPVPNLT WR + GD+TS FNFAAPP+PS PNLDHP Q LPK+ +CVPN VL Sbjct 428 RARFGVPVPNLTAWRDATVGDITSTFNFAAPPNPSKPNLDHPRAQCALPKLPQCVPNAVL 487 Query 476 GFLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 G + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 488 GTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 521 >gi|254232495|ref|ZP_04925822.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis C] gi|124601554|gb|EAY60564.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis C] Length=486 Score = 645 bits (1663), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/486 (67%), Positives = 381/486 (79%), Gaps = 5/486 (1%) Query 27 IEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYFGTLSAVDGFDTPTPLFQQKGWNPETQ 86 +++ GPC GHLTDIEHIVL +QENRSFDHYFGTLS+ +GF+ +P FQQ GWNP TQ Sbjct 1 MKRPTAPGPCPGHLTDIEHIVLLMQENRSFDHYFGTLSSTNGFNAASPAFQQMGWNPMTQ 60 Query 87 ALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGWLPAQARTRSVAN 146 ALDP G+T+P+R++TT GP GECVNDP+HQW+ HL+WNGGAND WLPAQA TR+ Sbjct 61 ALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQWVGMHLAWNGGANDNWLPAQATTRAGPY 120 Query 147 TPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISATVNPDGDQGGPQI 206 P+ MGYY R DIPIHYLLADTFTICD Y SLL GT+PNRLYW+SA ++P G GGPQ+ Sbjct 121 VPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLLTGTLPNRLYWLSANIDPAGTDGGPQL 180 Query 207 VEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKQAADPRS 266 VEP P F+WRIMP+NL DAG+SWKVY +K LG +T +S NG V +F+QAADPRS Sbjct 181 VEPGFLPLQQFSWRIMPENLEDAGVSWKVYQNKGLGRFINTPISNNGLVQAFRQAADPRS 240 Query 267 DLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGAVTIVNLIRVLLR 326 +LARYGIAP YP DF DV N LP+VSW+VP ++SEHP+ PVA+GAV++V +R+LL Sbjct 241 NLARYGIAPTYPGDFAADVRANRLPKVSWLVPNILQSEHPALPVALGAVSMVTALRILLS 300 Query 327 NPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVDGSGGIRGPIGLG 386 NPAVWEKTALI++YDE+GGFFDHVTP TAP GTPGE++ +ID V GSGGIRGP+GLG Sbjct 301 NPAVWEKTALIVSYDENGGFFDHVTPPTAPPGTPGEFV-TVPNIDAVPGSGGIRGPLGLG 359 Query 387 FRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRASVTGDMTSAFNFA 446 FRVPC VISPYSRG LMV D FDHTSQL+LI RFGVPVPN+T WR V GDMTSAFNFA Sbjct 360 FRVPCIVISPYSRGPLMVSDTFDHTSQLKLIRARFGVPVPNMTAWRDGVVGDMTSAFNFA 419 Query 447 APPDPSPPNLDHPVR-QLPKVAKCVPNVVLGFLNEGL---PYRVPYPQTTPVQESGPARP 502 PP+ + PNL HP+ LPK+ +C+PNVVLG + L PYRVPYPQ P QE+ P R Sbjct 420 TPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTDGALPSIPYRVPYPQVMPTQETTPVRG 479 Query 503 IPSGIC 508 PSG+C Sbjct 480 TPSGLC 485 >gi|183984690|ref|YP_001852981.1| membrane-associated phospholipase C 2 PlcB_6 [Mycobacterium marinum M] gi|183178016|gb|ACC43126.1| membrane-associated phospholipase C 2 PlcB_6 [Mycobacterium marinum M] Length=518 Score = 645 bits (1663), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/510 (65%), Positives = 381/510 (75%), Gaps = 3/510 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR FLAK A A + L A PVIEKAYGAGPCSGHLTDIEHIVL +QENRSFDHYF Sbjct 10 MSRREFLAKLAAATSTGALMSLAGPVIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYF 69 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS V+GFDTPTPLF QKGWNP TQA DP TLP+R++TT P G CVNDPDH W Sbjct 70 GTLSDVEGFDTPTPLFAQKGWNPRTQAPDPASTTLPFRLDTTRPPLLNGACVNDPDHGWA 129 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 H SWNGGAND WLPAQARTRS AN P +GY+ R D+PIH+LLADTFT+CD YF S++ Sbjct 130 TLHDSWNGGANDNWLPAQARTRSAANIPATLGYHTRDDLPIHFLLADTFTVCDHYFCSVI 189 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 G T PNRLYW+SA ++PDG GGP + P F+W IMPQ+LSDAG+SWK+Y K Sbjct 190 GPTFPNRLYWVSAWLDPDGANGGPLVETIPTPPIGKFSWPIMPQHLSDAGVSWKIYYDKR 249 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LG ++ + V F QA DPRSDL R+G P YP DF DV N LPQVSW++P Sbjct 250 LGPAVNSYVGYGEIVRWFTQAQDPRSDLVRFGATPRYPRDFATDVKANRLPQVSWLIPNF 309 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 +ESEHP+ P A GA+ ++++R+LL NPAVWEKTALI++YDE+GGFFDHV P T P+GTP Sbjct 310 LESEHPAMPNAGGAIAFMDVLRILLSNPAVWEKTALIVSYDENGGFFDHVVPPTPPDGTP 369 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GE++ DIDKV GSGGIRGPIGLG+RVP VISP+SRGGL+ HD FDHTSQL+LI R Sbjct 370 GEYL-TVPDIDKVRGSGGIRGPIGLGYRVPGLVISPFSRGGLVAHDVFDHTSQLRLIETR 428 Query 421 FGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQLPKVAKCVPNV--VLGFL 478 FGVPVPNLT WR SVTGDMTSAFNF PP+PS PNL+ R LP++A+C V V G Sbjct 429 FGVPVPNLTAWRRSVTGDMTSAFNFGVPPNPSRPNLNQSKRVLPQLAQCGLGVEAVAGIF 488 Query 479 NEGLPYRVPYPQTTPVQESGPARPIPSGIC 508 PYRVPYPQ P QE+ PAR IPSG+C Sbjct 489 ELNPPYRVPYPQAMPAQETTPARGIPSGLC 518 >gi|183980315|ref|YP_001848606.1| membrane-associated phospholipase C 2 PlcB_3 [Mycobacterium marinum M] gi|183173641|gb|ACC38751.1| membrane-associated phospholipase C 2 PlcB_3 [Mycobacterium marinum M] Length=580 Score = 640 bits (1650), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/514 (66%), Positives = 386/514 (76%), Gaps = 7/514 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 MSRR F+AK A A +A L A PVIEKAYGAGPCSGHLTDIEHIVL +QENRSFDHYF Sbjct 68 MSRRQFMAKLAAASSAGALMSLAGPVIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYF 127 Query 61 GTLSAVDGFDTPT--PLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 118 GTLS V GFD T +F QKGW+P TQ++DP GIT P+R +TT GP GECVNDP Sbjct 128 GTLSGVRGFDDTTDPAIFDQKGWDPRTQSIDPAGITSPFRFDTTRGPLLNGECVNDPVEG 187 Query 119 WIAAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSS 178 W+A H +WN GAND WLP+Q N P MGYY R D+PIHY+LADTFTICD Y+ S Sbjct 188 WVAMHTAWNNGANDTWLPSQYSQIRQGNIPACMGYYTRADLPIHYMLADTFTICDDYYCS 247 Query 179 LLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNS 238 +L GT PNRLYW+SA ++PDG GGP + EP P F+WRIMP+NL DAGISWKVY + Sbjct 248 MLTGTAPNRLYWLSAWIDPDGTNGGPLLNEPNFLPLQPFSWRIMPENLEDAGISWKVYQN 307 Query 239 KLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVP 298 K G ++ +S NG V +FKQ ADPRS+LAR+GIAP YP DF+ DV N LP+VSWVVP Sbjct 308 KFFGHYINSPISDNGLVQAFKQTADPRSNLARFGIAPTYPQDFVLDVKANRLPKVSWVVP 367 Query 299 LTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEG 358 ++SEHP+ PV VGAV IVN++R LL NPAVWEKTALII+YDE G FFDHVTP TAP G Sbjct 368 NIIQSEHPALPVNVGAVAIVNILRTLLSNPAVWEKTALIISYDECGSFFDHVTPPTAPPG 427 Query 359 TPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIG 418 TPGE++ DID V GSGGIRGPIGLG+RVPC VISPYSRG L+V D FDHTSQL+LI Sbjct 428 TPGEYV-TVPDIDAVSGSGGIRGPIGLGYRVPCIVISPYSRGPLVVSDTFDHTSQLRLIE 486 Query 419 KRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLGF 477 RFGVPVPNLTPWR SVT DMTSAFNFA PP+PS P LD P + LP++ +CVPN VLG Sbjct 487 TRFGVPVPNLTPWRRSVTEDMTSAFNFAVPPNPSRPKLDPPLLNALPRLPQCVPNAVLGS 546 Query 478 LNEGL---PYRVPYPQTTPVQESGPARPIPSGIC 508 L PYRVPYPQ P QE+ PAR PSG C Sbjct 547 LGGAAVANPYRVPYPQVPPTQETTPARGTPSGPC 580 >gi|340626764|ref|YP_004745216.1| phospholipase c 4 [Mycobacterium canettii CIPT 140010059] gi|340004954|emb|CCC44102.1| phospholipase c 4 [Mycobacterium canettii CIPT 140010059] Length=530 Score = 613 bits (1581), Expect = 2e-173, Method: Compositional matrix adjust. Identities = 302/434 (70%), Positives = 350/434 (81%), Gaps = 3/434 (0%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 +SRR FLAK A GA A+++ +A PVIEKAYGAGPCSGHLTDIEH V +QENRSFDHYF Sbjct 9 VSRREFLAKVAAGGAGALMS-FAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYF 67 Query 61 GTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWI 120 GTLS DGF+T +PLFQQKGWNP TQALD TG+T+PYR +TT GP G CVNDPDH W+ Sbjct 68 GTLSGTDGFNTVSPLFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHSWV 127 Query 121 AAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLL 180 A H SWNGG ND WLPAQA+TRS A+TP VMGYY R DIPIHYLLAD FT+CD+YF S+L Sbjct 128 AMHESWNGGVNDNWLPAQAKTRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFCSVL 187 Query 181 GGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKL 240 G T+PNRLYW+SAT++PDG GGP++ P QP F WRIMPQNLSDAG+SWKVY +K Sbjct 188 GPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYRNKT 247 Query 241 LGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLT 300 LG ++ L+ V SFKQ+ADPRSDL R+G+AP+YP F DV+ N LP+VSWV+P Sbjct 248 LGPISSV-LTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNV 306 Query 301 VESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTP 360 +ESEHP+ P A GA IVN++R+LL NPAVWEKTALI++YDE+GGFFDHV P TAP GTP Sbjct 307 LESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTP 366 Query 361 GEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKR 420 GE++ DID+V GSGGIRGPIGLGFRVPCFVISPYSRG MVHD FDHTSQL+L+ R Sbjct 367 GEYV-TVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLETR 425 Query 421 FGVPVPNLTPWRAS 434 FGVPVPNLT WR S Sbjct 426 FGVPVPNLTAWRRS 439 >gi|333918704|ref|YP_004492285.1| phospholipase C [Amycolicicoccus subflavus DQS3-9A1] gi|333480925|gb|AEF39485.1| Phospholipase C [Amycolicicoccus subflavus DQS3-9A1] Length=529 Score = 522 bits (1345), Expect = 5e-146, Method: Compositional matrix adjust. Identities = 278/508 (55%), Positives = 342/508 (68%), Gaps = 9/508 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCS-GHLTDIEHIVLCLQENRSFDHY 59 MSRR F AKA AG +LT WA PVIE+AY A P G L DIEH VL + ENRSFDHY Sbjct 29 MSRREFFAKAFAAGGTVLLTSWAGPVIERAYAADPMGHGTLDDIEHFVLLMLENRSFDHY 88 Query 60 FGTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQW 119 FGT S V GFD P+ + Q G+ P PTG P+R++TT G GEC+NDP H W Sbjct 89 FGTQSGVRGFDDPSAAWNQYGYAPGIGP-TPTGFLNPFRLDTTRGATLNGECINDPTHSW 147 Query 120 IAAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSL 179 H +WNGG D W+ + N P MGYY R D+P+HY L D FT+CD YF S+ Sbjct 148 GPQHHAWNGGRMDQWVTVHLQHEGPGNGPATMGYYTRDDLPVHYQLTDAFTLCDHYFCSV 207 Query 180 LGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSK 239 +G T PNRLYWISA+++P G GGP + P + P+ ++WR P+NL +AG+SWKVY +K Sbjct 208 MGPTDPNRLYWISASIDPAGTHGGPLVYTPELLPQHVYSWRTFPENLEEAGVSWKVYQNK 267 Query 240 LLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPL 299 G L+ L +G +G F Q+ADP+S L R G+AP YP +F DV N TLPQVSW+VP Sbjct 268 DFGPLSSVLL--DGMLGCFVQSADPQSALYRKGVAPTYPLEFQNDVQNGTLPQVSWIVPS 325 Query 300 TVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGT 359 +E EHP+ P A GAV +V ++ +L N A+WEKTALI++YDE+GGFFDHV P TAP GT Sbjct 326 LLECEHPALPPAFGAVGLVQVLDILTSNRALWEKTALIVSYDENGGFFDHVAPPTAPPGT 385 Query 360 PGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGK 419 PGE++ + + V S GI GPIGLGFRVP V+SPYSRGGL+ D DHTSQL+LI K Sbjct 386 PGEYL--TAPLASVTESDGIAGPIGLGFRVPSMVVSPYSRGGLVFSDVLDHTSQLRLIEK 443 Query 420 RFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPV-RQLPKVAKCVPNVVLGFL 478 RFGVPVPNLTPWR SV GDM++AFNFAA PDP NL P + +A+C P++V GF Sbjct 444 RFGVPVPNLTPWRRSVVGDMSAAFNFAAAPDPGSVNLGTPWPKAGAALAQCGPDIVTGFF 503 Query 479 NEGLPYRVPYPQTTPVQESGPARPIPSG 506 N+G PY VP P + P QE G R PSG Sbjct 504 NQGTPYAVP-PNSMPRQEPG-TRGRPSG 529 >gi|111019467|ref|YP_702439.1| phospholipase C [Rhodococcus jostii RHA1] gi|110818997|gb|ABG94281.1| phospholipase C [Rhodococcus jostii RHA1] Length=511 Score = 513 bits (1320), Expect = 4e-143, Method: Compositional matrix adjust. Identities = 283/509 (56%), Positives = 348/509 (69%), Gaps = 8/509 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPC-SGHLTDIEHIVLCLQENRSFDHY 59 +SRR FLA AA AG AA L+ WA PVI++AY P SG L DIEH V +QENRSFDHY Sbjct 7 ISRRKFLASAAAAGGAAFLSSWAGPVIDRAYAQDPGGSGSLNDIEHFVYLMQENRSFDHY 66 Query 60 FGTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQW 119 +GTLS V GFD P+P +QQ GW P PTG P+R++TT G + GEC+NDP H W Sbjct 67 YGTLSGVRGFDDPSPAWQQYGWTPGAGPT-PTGFLNPFRLDTTQGAHLDGECINDPTHSW 125 Query 120 IAAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSL 179 H +WNGGA D W+P N P MGYY R DIP+HY LAD FTICD YF S+ Sbjct 126 GPQHDAWNGGAMDRWMPVHIAHEGPLNGPATMGYYTRADIPVHYDLADAFTICDHYFCSV 185 Query 180 LGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSK 239 LG T PNRLYW++ T++PDG GGP + P + PK ++WR P+NL +AG+SWKVY +K Sbjct 186 LGPTDPNRLYWMTGTIDPDGLAGGPLVETPTVIPKFVYSWRTYPENLQEAGVSWKVYANK 245 Query 240 LLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPL 299 LG + +S++ +G +G F Q +DP S+LAR G+ P YP DF DV N TLP VSW+VP Sbjct 246 DLGPV--SSVALDGMLGCFTQYSDPNSELARRGLDPTYPNDFRADVANGTLPAVSWIVPN 303 Query 300 TVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGT 359 EHP+ P A GAV IV ++ +L NPA+WEKTALII+YDE+GGFFDHVTP T P GT Sbjct 304 IFTCEHPALPPAAGAVGIVEVLDILTSNPAIWEKTALIISYDENGGFFDHVTPPTPPPGT 363 Query 360 PGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGK 419 PGE++ +V ++ V S GPIGLGFRVP +ISPYSRGGL+ D FDHTSQL+L+ K Sbjct 364 PGEYL--TVPLNTVSESENNPGPIGLGFRVPSLIISPYSRGGLVASDTFDHTSQLRLLEK 421 Query 420 RFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQL-PKVAKCVPNVVLGFL 478 RFGVPVPNLT WR GDMTSAF+F++ P+ P + P +L +A+C PNV G L Sbjct 422 RFGVPVPNLTEWRRGAVGDMTSAFDFSSAPNAGVPAMTDPGPRLQAAIAQCGPNVAAGTL 481 Query 479 NEGLPYRVPYPQTTPVQESGPARPIPSGI 507 N G PY VP P + PVQE P R PSG+ Sbjct 482 NAGAPYPVP-PNSMPVQEQSPLRRRPSGL 509 >gi|226361617|ref|YP_002779395.1| phospholipase C [Rhodococcus opacus B4] gi|226240102|dbj|BAH50450.1| phospholipase C [Rhodococcus opacus B4] Length=511 Score = 509 bits (1312), Expect = 4e-142, Method: Compositional matrix adjust. Identities = 281/509 (56%), Positives = 348/509 (69%), Gaps = 8/509 (1%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPC-SGHLTDIEHIVLCLQENRSFDHY 59 +SRR FLA AA AG AA L+ WA PVI++AY P SG L DIEH V +QENRSFDHY Sbjct 7 ISRRKFLASAAAAGGAAFLSSWAGPVIDRAYAQDPGGSGSLNDIEHFVYLMQENRSFDHY 66 Query 60 FGTLSAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQW 119 +GTLS V GFD P+P +QQ GW P PTG P+R++TT G + GEC+NDP H W Sbjct 67 YGTLSGVRGFDDPSPAWQQYGWTPGAGPT-PTGFLEPFRLDTTQGTHLDGECINDPTHSW 125 Query 120 IAAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSL 179 H +WNGGA D W+P N P MGYY R DIP+HY LAD FTICD YF S+ Sbjct 126 GPQHDAWNGGAMDRWMPVHIAHEGPLNGPATMGYYTRADIPVHYDLADAFTICDHYFCSV 185 Query 180 LGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSK 239 LG T PNRLYW++ T++PDG GGP + P + P+ ++WR P+NL +AG+ WKVY +K Sbjct 186 LGPTDPNRLYWMTGTIDPDGLAGGPLVETPTVIPRFAYSWRTYPENLQEAGVGWKVYANK 245 Query 240 LLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPL 299 LG + +S++ +G +G FKQ +DP S+LAR G+ P YP DF DV N TLP VSW+VP Sbjct 246 DLGPV--SSVALDGMLGCFKQYSDPNSELARRGLDPTYPNDFRADVANGTLPAVSWIVPN 303 Query 300 TVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGT 359 EHP+ P A GAV IV ++ +L NPA+WEKTALII+YDE+GGFFDHVTP T P GT Sbjct 304 IFTCEHPALPPAAGAVGIVEVLDILTSNPAIWEKTALIISYDENGGFFDHVTPPTPPPGT 363 Query 360 PGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGK 419 PGE++ +V ++ V S GPIGLGFRVP +ISPYSRGGL+ D FDHTSQL+L+ + Sbjct 364 PGEYL--TVPLNTVAESENNPGPIGLGFRVPSLIISPYSRGGLVASDTFDHTSQLRLLEQ 421 Query 420 RFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHPVRQL-PKVAKCVPNVVLGFL 478 RFGVPVPNLT WR GDMTSAF+F++ P+ P + P +L +A+C PNV G L Sbjct 422 RFGVPVPNLTEWRRGAVGDMTSAFDFSSAPNAGVPAMTDPGPRLQAAIAQCGPNVAAGTL 481 Query 479 NEGLPYRVPYPQTTPVQESGPARPIPSGI 507 N G PY VP P + PVQE P R PSG+ Sbjct 482 NAGAPYPVP-PNSMPVQEPSPLRRRPSGL 509 >gi|308401612|ref|ZP_07669413.1| phosphoesterase family protein [Mycobacterium tuberculosis SUMu012] gi|308366040|gb|EFP54891.1| phosphoesterase family protein [Mycobacterium tuberculosis SUMu012] Length=414 Score = 480 bits (1235), Expect = 3e-133, Method: Compositional matrix adjust. Identities = 241/374 (65%), Positives = 286/374 (77%), Gaps = 3/374 (0%) Query 136 PAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISATV 195 PA+ + V+ + YY R DIPIHYLLAD FT+CD+YF S+LG T+PNRLYW+SAT+ Sbjct 43 PAEVSDQRVSGLTGAVHYYTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNRLYWLSATI 102 Query 196 NPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYV 255 +PDG GGP++ P QP F WRIMPQNLSDAG+SWKVY +K LG ++ L+ V Sbjct 103 DPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYRNKTLGPISSV-LTYGSLV 161 Query 256 GSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGAV 315 SFKQ+ADPRSDL R+G+AP+YP F DV+ N LP+VSWV+P +ESEHP+ P A GA Sbjct 162 TSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNVLESEHPAVPAAAGAF 221 Query 316 TIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVDG 375 IVN++R+LL NPAVWEKTALI++YDE+GGFFDHV P TAP GTPGE++ DID+V G Sbjct 222 AIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTPGEYV-TVPDIDQVPG 280 Query 376 SGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRASV 435 SGGIRGPIGLGFRVPCFVISPYSRG MVHD FDHTSQL+L+ RFGVPVPNLT WR SV Sbjct 281 SGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSV 340 Query 436 TGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLGFLNEGLPYRVPYPQTTPV 494 TGDMTS FNFA PP+ S PNLD+P + L V +CVPN LG +N G+PYRVP PQ P Sbjct 341 TGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGTINRGIPYRVPDPQIMPT 400 Query 495 QESGPARPIPSGIC 508 QE+ P R IPSG C Sbjct 401 QETTPTRGIPSGPC 414 >gi|148661554|ref|YP_001283077.1| putative phospholipase C 4 PlcD [Mycobacterium tuberculosis H37Ra] gi|167968627|ref|ZP_02550904.1| phospholipase C plcD [Mycobacterium tuberculosis H37Ra] gi|148505706|gb|ABQ73515.1| putative phospholipase C 4 PlcD [Mycobacterium tuberculosis H37Ra] Length=343 Score = 453 bits (1166), Expect = 3e-125, Method: Compositional matrix adjust. Identities = 227/345 (66%), Positives = 269/345 (78%), Gaps = 3/345 (0%) Query 165 LADTFTICDQYFSSLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQ 224 +AD FT+CD+YF S+LG T+PNRLYW+SAT++PDG GGP++ P QP F WRIMPQ Sbjct 1 MADAFTVCDRYFCSVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQ 60 Query 225 NLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRD 284 NLSDAG+SWKVY +K LG ++ L+ V SFKQ+ADPRSDL R+G+AP+YP F D Sbjct 61 NLSDAGVSWKVYRNKTLGPISSV-LTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAAD 119 Query 285 VINNTLPQVSWVVPLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHG 344 V+ N LP+VSWV+P +ESEHP+ P A GA IVN++R+LL NPAVWEKTALI++YDE+G Sbjct 120 VLANRLPRVSWVIPNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENG 179 Query 345 GFFDHVTPLTAPEGTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMV 404 GFFDHV P TAP GTPGE++ DID+V GSGGIRGPIGLGFRVPCFVISPYSRG MV Sbjct 180 GFFDHVVPATAPAGTPGEYV-TVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMV 238 Query 405 HDRFDHTSQLQLIGKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQL 463 HD FDHTSQL+L+ RFGVPVPNLT WR SVTGDMTS FNFA PP+ S PNLD+P + L Sbjct 239 HDTFDHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHAL 298 Query 464 PKVAKCVPNVVLGFLNEGLPYRVPYPQTTPVQESGPARPIPSGIC 508 V +CVPN LG +N G+PYRVP PQ P QE+ P R IPSG C Sbjct 299 STVPQCVPNAALGTINRGIPYRVPDPQIMPTQETTPTRGIPSGPC 343 >gi|289575348|ref|ZP_06455575.1| predicted protein [Mycobacterium tuberculosis K85] gi|289539779|gb|EFD44357.1| predicted protein [Mycobacterium tuberculosis K85] Length=252 Score = 388 bits (996), Expect = 1e-105, Method: Compositional matrix adjust. Identities = 189/196 (97%), Positives = 189/196 (97%), Gaps = 0/196 (0%) Query 4 RAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYFGTL 63 RAFLAKAAGA AVLTD AA IEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYFGTL Sbjct 57 RAFLAKAAGALTYAVLTDCAAAAIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYFGTL 116 Query 64 SAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAH 123 SAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRIN TGGPNGVGECVNDPDHQWIAAH Sbjct 117 SAVDGFDTPTPLFQQKGWNPETQALDPTGITLPYRINITGGPNGVGECVNDPDHQWIAAH 176 Query 124 LSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGT 183 LSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGT Sbjct 177 LSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGT 236 Query 184 MPNRLYWISATVNPDG 199 MPNRLYWISATVNPDG Sbjct 237 MPNRLYWISATVNPDG 252 >gi|15608893|ref|NP_216271.1| phospholipase C 4 PLCD [Mycobacterium tuberculosis H37Rv] gi|3242246|emb|CAB09340.1| PROBABLE PHOSPHOLIPASE C 4 (FRAGMENT) PLCD [Mycobacterium tuberculosis H37Rv] Length=280 Score = 363 bits (932), Expect = 3e-98, Method: Compositional matrix adjust. Identities = 187/282 (67%), Positives = 219/282 (78%), Gaps = 3/282 (1%) Query 228 DAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVIN 287 DAG+SWKVY +K LG ++ L+ V SFKQ+ADPRSDL R+G+AP+YP F DV+ Sbjct 1 DAGVSWKVYRNKTLGPISSV-LTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLA 59 Query 288 NTLPQVSWVVPLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFF 347 N LP+VSWV+P +ESEHP+ P A GA IVN++R+LL NPAVWEKTALI++YDE+GGFF Sbjct 60 NRLPRVSWVIPNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFF 119 Query 348 DHVTPLTAPEGTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDR 407 DHV P TAP GTPGE++ DID+V GSGGIRGPIGLGFRVPCFVISPYSRG MVHD Sbjct 120 DHVVPATAPAGTPGEYV-TVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDT 178 Query 408 FDHTSQLQLIGKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKV 466 FDHTSQL+L+ RFGVPVPNLT WR SVTGDMTS FNFA PP+ S PNLD+P + L V Sbjct 179 FDHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTV 238 Query 467 AKCVPNVVLGFLNEGLPYRVPYPQTTPVQESGPARPIPSGIC 508 +CVPN LG +N G+PYRVP PQ P QE+ P R IPSG C Sbjct 239 PQCVPNAALGTINRGIPYRVPDPQIMPTQETTPTRGIPSGPC 280 >gi|256389818|ref|YP_003111382.1| phospholipase C [Catenulispora acidiphila DSM 44928] gi|256356044|gb|ACU69541.1| Phospholipase C [Catenulispora acidiphila DSM 44928] Length=542 Score = 358 bits (919), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 203/478 (43%), Positives = 267/478 (56%), Gaps = 30/478 (6%) Query 42 DIEHIVLCLQENRSFDHYFGTLSAVDGFDTPT-----------PLFQQKGWNPETQALDP 90 D+EH+V+ +QENRSFD YFGTLS V GF P +F Q G+ P A Sbjct 75 DVEHVVVLMQENRSFDQYFGTLSGVRGFSDPAVPTQTVGGTEYTVFNQFGFAPGIGA-SA 133 Query 91 TGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGWLPAQARTRSVANTPVV 150 +G P+++ + P G+ ND H W H SWN GA D ++ A AN PV Sbjct 134 SGYLQPFQL-VSNPPLENGQTTNDVSHSWATQHQSWNHGAMDSFITAHLAADGAANGPVT 192 Query 151 MGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISATVNPDGDQGGP--QIVE 208 MGY+ R D+ ++ LAD FTICD Y S+LG T PNRL +SA+++P+G GGP + Sbjct 193 MGYFTRQDLAFYHALADAFTICDGYHCSVLGPTDPNRLMLMSASIDPEGAHGGPVVETFS 252 Query 209 PAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKQAADPRS-D 267 I +W MP+ L AG+SWKVYN + GL +LS Y ++ P + Sbjct 253 NRIGETGKLSWETMPERLLAAGVSWKVYNDPI--GL--LALSPLPYFKNYDNPFSPTGLE 308 Query 268 LARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGAVTIVNLIRVLLRN 327 L G+ P+YP DF D+ LP VSW++P + EHP+ P G + ++ L+ N Sbjct 309 LIGRGLTPSYPHDFKSDIAAGKLPSVSWIIPPVAQCEHPAAPPYYGEYFVQEVLAALVSN 368 Query 328 PAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVDGSGGIRGPIGLGF 387 P VW +T + + YDE+GGFFDHV P TAPEGT GEW+ +GG+ GPIGLGF Sbjct 369 PEVWARTVVFVVYDENGGFFDHVAPPTAPEGTAGEWLAT-----LPSAAGGVDGPIGLGF 423 Query 388 RVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRASVTGDMTSAFNFAA 447 R P V+SP+S GG DHTS L+ I RFGV VPNLT WR VTGD T A N A Sbjct 424 RTPALVLSPFSVGGYKYSGTLDHTSVLRFIESRFGVEVPNLTAWRRGVTGDFTGALNLTA 483 Query 448 PPDPSPPNLDHPVRQLPKVA---KCVPNVVLGFLNEGLPYRVPYPQTTPVQESGPARP 502 P +P+ P L PV + + + V N + G L+ G+PY +P + P QES PARP Sbjct 484 PANPAFPTL--PVVNIGDTSVAEQAVLNALAGTLDVGIPYPLPTSNSMPSQESTPARP 539 >gi|329937895|ref|ZP_08287377.1| phospholipase C [Streptomyces griseoaurantiacus M045] gi|329302852|gb|EGG46741.1| phospholipase C [Streptomyces griseoaurantiacus M045] Length=476 Score = 332 bits (850), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 191/451 (43%), Positives = 249/451 (56%), Gaps = 34/451 (7%) Query 25 PVIEKAYGAGP-CSGHLTDIEHIVLCLQENRSFDHYFGTLSAVDGFDTPTPLFQQKG--- 80 P ++KA AGP G L DIEH+VL +QENRSFDHYFGTLS V GF P L G Sbjct 29 PSVQKAVAAGPPKHGSLRDIEHVVLLMQENRSFDHYFGTLSGVRGFHDPRALKLDTGRSV 88 Query 81 -WNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGWLPAQA 139 + P+TQ +P G LP+ ++T + + H W H +WNGG D WLPA Sbjct 89 FFQPDTQ--NPRGYLLPFHLDTHAS---SAQAIPSTSHAWTVQHEAWNGGKMDRWLPAHR 143 Query 140 RTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISATVNPDG 199 + V N P VMGYY R DIP + LA+TFT+CD YF S+ G T PNRLYW++ T++P G Sbjct 144 KADGV-NGPYVMGYYTREDIPFQFALAETFTVCDAYFCSVFGPTWPNRLYWMTGTLDPGG 202 Query 200 DQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFK 259 +GGP + A P + W + L AG+SWKVY +D + +F+ Sbjct 203 TRGGPILTNKAPTP---YRWTTYAERLQAAGVSWKVYQQD-----DDYGCNLLEQFAAFR 254 Query 260 QAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGAVTIVN 319 +A P SDL G+ P F D N+ LP VSW++P + +SEHP + A GA + + Sbjct 255 EA-QPGSDLYERGMRPQPEGTFEEDARNDRLPAVSWIIPTSHQSEHPDYLPAAGADFVAS 313 Query 320 LIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVDGSGGI 379 I + NP VW KTA I+ YDE+ G FDHV P T PEGT E++ G+ Sbjct 314 KIEAIASNPKVWRKTAFILNYDENDGLFDHVPPPTPPEGTKDEFV------------QGL 361 Query 380 RGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRASVTGDM 439 PIG GFRVP VISP++ GG + + FDHTS LQ + K GV PN++ WR GD+ Sbjct 362 --PIGGGFRVPAVVISPWTVGGWVASEPFDHTSVLQFLEKFTGVAEPNISDWRRETFGDL 419 Query 440 TSAFNFAAPPDPSPPNLDHPVRQLPKVAKCV 470 TSAF F + P + QL K + V Sbjct 420 TSAFRFRSAHRRPPRLPEDTAEQLEKAKEEV 450 >gi|298525835|ref|ZP_07013244.1| predicted protein [Mycobacterium tuberculosis 94_M4241A] gi|298495629|gb|EFI30923.1| predicted protein [Mycobacterium tuberculosis 94_M4241A] Length=253 Score = 324 bits (831), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 171/248 (69%), Positives = 198/248 (80%), Gaps = 3/248 (1%) Query 263 DPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGAVTIVNLIR 322 DPRS+LAR+GI+P YP DF DV NN LP+VSWV+P + SEHP+FPV VGAV IV+ +R Sbjct 7 DPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALR 66 Query 323 VLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVDGSGGIRGP 382 +LL NPAVWEKTALI+ YDE+GGFFDHV P T P GTPGE++ DID V GSGGIRGP Sbjct 67 ILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFV-TVPDIDSVPGSGGIRGP 125 Query 383 IGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRASVTGDMTSA 442 IGLGFRVPC VISPYSRG LMVHD FDHTS L+LI RFGVPVPNLT WR + GDMTS Sbjct 126 IGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTST 185 Query 443 FNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLGFLNE-GLPYRVPYPQTTPVQESGPA 500 FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG + + +PYRVP+PQ+ P QE+ P Sbjct 186 FNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKTAIPYRVPFPQSMPTQETAPT 245 Query 501 RPIPSGIC 508 R IPSG+C Sbjct 246 RGIPSGLC 253 >gi|302544869|ref|ZP_07297211.1| phospholipase C [Streptomyces hygroscopicus ATCC 53653] gi|302462487|gb|EFL25580.1| phospholipase C [Streptomyces himastatinicus ATCC 53653] Length=511 Score = 318 bits (816), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 187/455 (42%), Positives = 245/455 (54%), Gaps = 36/455 (7%) Query 25 PVIEKAYGAGP-CSGHLTDIEHIVLCLQENRSFDHYFGTLSAVDGFDTPTPLFQQKGWNP 83 P +++A AGP G L DIEH+VL +QENRSFDHYFGTL V GF P L G + Sbjct 64 PSVQQAIAAGPPQGGSLDDIEHVVLLMQENRSFDHYFGTLKGVRGFADPDALTLSTGKSV 123 Query 84 ETQ--ALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGWLPAQART 141 Q ++P G LP+R++T + + + H W H +WNGGA D WLPA R Sbjct 124 FHQPDEVNPDGYLLPFRLDTR---STSAQAIPSTSHAWSVQHEAWNGGAMDKWLPAH-RK 179 Query 142 RSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISATVNPDGDQ 201 N P VMGY+ R DIP + LA+ FT+CD YF S+ G T PNRLYW++ T++P G + Sbjct 180 ADGENGPYVMGYHTREDIPFQFALAEAFTVCDNYFCSVFGPTWPNRLYWMTGTIDPAGVK 239 Query 202 GGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNGYVGSFKQA 261 GGP + A +P + W + L AG+SWKVY + G N + F+Q Sbjct 240 GGPVLENKAPKP---YRWTTYAERLQKAGVSWKVYQEEDNYGCN--------LLEEFQQF 288 Query 262 ADPR--SDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVGAVTIVN 319 D R L G+ + F D N+ LP VSW++P SEHP + A GA + + Sbjct 289 QDARPGDPLYDRGMVHSPAGTFEGDARNDRLPTVSWIIPTAEVSEHPDYLPAAGADYVAS 348 Query 320 LIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKVDGSGGI 379 I + NP VW KT I+ YDE+ G FDHV P T GT E++ GG+ Sbjct 349 KIEAIASNPDVWRKTVFILNYDENDGLFDHVPPPTPKAGTVDEFV------------GGL 396 Query 380 RGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRASVTGDM 439 PIG GFRVPC ++SP++ GG FDHTS LQ + + GV PN++ WR GD+ Sbjct 397 --PIGGGFRVPCLIVSPWTVGGWAAGQAFDHTSVLQFLERLTGVKEPNISEWRRRTFGDL 454 Query 440 TSAFNFAAPPDPSPPNL-DHPVRQLPKVAKCVPNV 473 TSAF F P PP L D QL K + V N+ Sbjct 455 TSAFGFGNAA-PEPPKLPDDTAEQLEKAKEDVENL 488 >gi|299139454|ref|ZP_07032629.1| Phospholipase C [Acidobacterium sp. MP5ACTX8] gi|298598723|gb|EFI54886.1| Phospholipase C [Acidobacterium sp. MP5ACTX8] Length=496 Score = 316 bits (810), Expect = 6e-84, Method: Compositional matrix adjust. Identities = 184/462 (40%), Positives = 256/462 (56%), Gaps = 36/462 (7%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGP-CSGHLTDIEHIVLCLQENRSFDHY 59 ++RR L AA + A + P ++K GP +G + DI+H+V+ +QENRSFDHY Sbjct 14 VTRRRLLKGAAQLASVAAASSLMPPNVQKLLAQGPPKNGSMKDIKHVVVLMQENRSFDHY 73 Query 60 FGTLSAVDGFDTPTPLFQQKG----WNPETQALDPTGITLPYRINTTGGPNGVGECVNDP 115 FG L+ V GF+ P L G + P+T ++P G LP+ ++T + + V Sbjct 74 FGMLAGVRGFNDPHALQLSTGKSVFYQPDT--VNPKGYMLPFHLDTQ---STNAQKVPST 128 Query 116 DHQWIAAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQY 175 +H W+ H +WNGG + WLPA R A+ P MGYY R DIP Y LA+ FTICD Y Sbjct 129 NHGWVVQHQAWNGGRMNQWLPAH-RAADGAHGPYCMGYYKREDIPFQYALAEAFTICDSY 187 Query 176 FSSLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKV 235 S++G T PNR+YW + T++PDG GGP I+ A P+ FTW + L +AG+SWKV Sbjct 188 HCSVMGPTWPNRMYWYTGTIDPDGRHGGPIIMNKA--PEGGFTWTTYAERLEEAGVSWKV 245 Query 236 YNSKLLGGLNDTSLSRNGY--VGSFKQAADPRSDLARY--GIAPAYPWDFIRDVINNTLP 291 Y N+ + G+ + +F++ D D Y G+ P +F D +++ LP Sbjct 246 YQYA-----NEDATHGVGFNMLHNFRKFQDAHKDSPLYTKGLVAVTPGEFEYDCLHDQLP 300 Query 292 QVSWVVPLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVT 351 VSWV P + SEHP A GA + ++I + NP VW KTA I+ YDE+ G FDHV Sbjct 301 AVSWVCPPHIASEHPDHLPAEGAAFVASIIDAIAANPDVWAKTAFILNYDENDGQFDHVQ 360 Query 352 PLTAPEGTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHT 411 P P+GT E++ G+ PIG GFRVPC ++SP++ GG + FDHT Sbjct 361 PPIPPKGTANEFV------------NGL--PIGGGFRVPCIIVSPWTTGGWVCSQNFDHT 406 Query 412 SQLQLIGKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSP 453 S +Q + K GV PN++ WR GDMTSAF F SP Sbjct 407 SVVQFLEKFTGVREPNISDWRRETFGDMTSAFRFDQASAKSP 448 >gi|295837178|ref|ZP_06824111.1| phospholipase C [Streptomyces sp. SPB74] gi|197698526|gb|EDY45459.1| phospholipase C [Streptomyces sp. SPB74] Length=524 Score = 315 bits (808), Expect = 8e-84, Method: Compositional matrix adjust. Identities = 184/479 (39%), Positives = 247/479 (52%), Gaps = 41/479 (8%) Query 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGP-CSGHLTDIEHIVLCLQENRSFDHY 59 M+RR L A A P + +A AGP G L D+EH+V+ +QENRSFDHY Sbjct 51 MTRRRLLGSAGTVVGATAALSLLPPSVREAVAAGPPHGGSLDDVEHVVMLMQENRSFDHY 110 Query 60 FGTLSAVDGFDTPTPLFQQKGWNPETQ--ALDPTGITLPYRINTTGGPNGVGECVNDPDH 117 FGT+ V GF+ P G + Q A P G TLP+ ++T + + H Sbjct 111 FGTMRGVRGFNDPRAQRLSTGRSVFYQPDAAHPDGYTLPFHLDTHAT---SAQAIPSTSH 167 Query 118 QWIAAHLSWNGGANDGWLPAQARTRSVANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 W H +WN G D WLPA R AN P VMGYY R DIP + LA+ FT+CD YF Sbjct 168 AWSVQHEAWNNGRMDNWLPAH-RKADGANGPYVMGYYTREDIPFQFALAEAFTVCDNYFC 226 Query 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 S+ G T PNR+YW++ T++P+G+ GGP + A P +TW + L AG+SWKVY Sbjct 227 SVFGPTWPNRMYWMTGTLDPNGEHGGPILDNTA--PAGGYTWTTYAERLEAAGVSWKVYQ 284 Query 238 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 297 +D + +F+ A P L G+ P F D LP VSW++ Sbjct 285 ED-----DDYGCNMLENFANFRD-AKPGDPLYEKGVRPQPTGTFEADARAGKLPTVSWII 338 Query 298 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 + +SEHP + A GA + + I + NP +W KTA I+ YDE+ G FDHV P T Sbjct 339 CTSEQSEHPDYLPAAGADYVASKIEAIASNPELWRKTAFILNYDENDGLFDHVVPPTPRP 398 Query 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 GTP E++ P+G GFRVPC ++SP++ GG + FDHTS LQ + Sbjct 399 GTPDEFVQGL--------------PVGGGFRVPCVIVSPWTAGGYAAGEAFDHTSVLQFL 444 Query 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNL-----------DHPVRQLPK 465 + GV PN++ WR GD+TSAF F +P PP+L H V+ LPK Sbjct 445 ERVTGVREPNISQWRRRTFGDLTSAFGFRSPAH-RPPHLPEDTAEQLEEARHEVKTLPK 502 Lambda K H 0.319 0.139 0.449 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1101757964944 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40