BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2350c Length=512 Score E Sequences producing significant alignments: (Bits) Value gi|15609487|ref|NP_216866.1| membrane-associated phospholipase C... 1044 0.0 gi|148823551|ref|YP_001288305.1| membrane-associated phospholipa... 1044 0.0 gi|308370983|ref|ZP_07423455.2| membrane-associated phospholipas... 1042 0.0 gi|306780388|ref|ZP_07418725.1| membrane-associated phospholipas... 1042 0.0 gi|289745624|ref|ZP_06505002.1| phospholipase C 2 [Mycobacterium... 988 0.0 gi|1399494|gb|AAC18944.1| phospholipase C [Mycobacterium tubercu... 956 0.0 gi|240173291|ref|ZP_04751949.1| membrane-associated phospholipas... 877 0.0 gi|183983797|ref|YP_001852088.1| membrane-associated phospholipa... 835 0.0 gi|240173292|ref|ZP_04751950.1| membrane-associated phospholipas... 785 0.0 gi|339298872|gb|AEJ50982.1| phospholipase C [Mycobacterium tuber... 781 0.0 gi|289758476|ref|ZP_06517854.1| conserved hypothetical protein [... 780 0.0 gi|15841858|ref|NP_336895.1| phospholipase C [Mycobacterium tube... 779 0.0 gi|15609488|ref|NP_216867.1| membrane-associated phospholipase C... 778 0.0 gi|183983547|ref|YP_001851838.1| membrane-associated phospholipa... 774 0.0 gi|118618235|ref|YP_906567.1| membrane-associated phospholipase ... 771 0.0 gi|183983637|ref|YP_001851928.1| membrane-associated phospholipa... 764 0.0 gi|339295253|gb|AEJ47364.1| membrane-associated phospholipase C ... 764 0.0 gi|240169308|ref|ZP_04747967.1| membrane-associated phospholipas... 764 0.0 gi|183980315|ref|YP_001848606.1| membrane-associated phospholipa... 750 0.0 gi|254232495|ref|ZP_04925822.1| membrane-associated phospholipas... 743 0.0 gi|308380173|ref|ZP_07669139.1| putative Tat (twin-arginine tran... 734 0.0 gi|15841221|ref|NP_336258.1| phospholipase C [Mycobacterium tube... 733 0.0 gi|240170410|ref|ZP_04749069.1| membrane-associated phospholipas... 727 0.0 gi|254231948|ref|ZP_04925275.1| phospholipase C 4 (fragment) plc... 724 0.0 gi|183981500|ref|YP_001849791.1| membrane-associated phospholipa... 723 0.0 gi|254551397|ref|ZP_05141844.1| phospholipase C 3 plcC [Mycobact... 693 0.0 gi|148823550|ref|YP_001288304.1| phospholipase C 3 plcC [Mycobac... 692 0.0 gi|183984690|ref|YP_001852981.1| membrane-associated phospholipa... 692 0.0 gi|15609486|ref|NP_216865.1| phospholipase C 3 PLCC [Mycobacteri... 692 0.0 gi|289575041|ref|ZP_06455268.1| phospholipase C 3 plcC [Mycobact... 690 0.0 gi|294994549|ref|ZP_06800240.1| phospholipase C 3 plcC [Mycobact... 690 0.0 gi|289758474|ref|ZP_06517852.1| conserved hypothetical protein [... 689 0.0 gi|240173290|ref|ZP_04751948.1| phospholipase C 3 plcC [Mycobact... 684 0.0 gi|183983636|ref|YP_001851927.1| membrane-associated phospholipa... 678 0.0 gi|340626764|ref|YP_004745216.1| phospholipase c 4 [Mycobacteriu... 631 8e-179 gi|289750954|ref|ZP_06510332.1| phospholipase C 3 plcC [Mycobact... 602 4e-170 gi|333918704|ref|YP_004492285.1| phospholipase C [Amycolicicoccu... 530 2e-148 gi|308401612|ref|ZP_07669413.1| phosphoesterase family protein [... 525 7e-147 gi|226361617|ref|YP_002779395.1| phospholipase C [Rhodococcus op... 521 1e-145 gi|111019467|ref|YP_702439.1| phospholipase C [Rhodococcus josti... 521 1e-145 gi|148661554|ref|YP_001283077.1| putative phospholipase C 4 PlcD... 500 2e-139 gi|298525835|ref|ZP_07013244.1| predicted protein [Mycobacterium... 495 8e-138 gi|217069518|gb|ACJ83246.1| Rv2349c antigen [Mycobacterium tuber... 468 8e-130 gi|15608893|ref|NP_216271.1| phospholipase C 4 PLCD [Mycobacteri... 410 2e-112 gi|256389818|ref|YP_003111382.1| phospholipase C [Catenulispora ... 384 2e-104 gi|289762518|ref|ZP_06521896.1| conserved hypothetical protein [... 376 6e-102 gi|295837178|ref|ZP_06824111.1| phospholipase C [Streptomyces sp... 356 5e-96 gi|302521121|ref|ZP_07273463.1| phospholipase C, phosphocholine-... 350 3e-94 gi|302544869|ref|ZP_07297211.1| phospholipase C [Streptomyces hy... 350 3e-94 gi|318058016|ref|ZP_07976739.1| non-hemolytic phospholipase C [S... 349 7e-94 >gi|15609487|ref|NP_216866.1| membrane-associated phospholipase C [Mycobacterium tuberculosis H37Rv] gi|15841857|ref|NP_336894.1| phospholipase C [Mycobacterium tuberculosis CDC1551] gi|148662178|ref|YP_001283701.1| membrane-associated phospholipase C 2 [Mycobacterium tuberculosis H37Ra] 36 more sequence titles Length=512 Score = 1044 bits (2700), Expect = 0.0, Method: Compositional matrix adjust. Identities = 512/512 (100%), Positives = 512/512 (100%), Gaps = 0/512 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF Sbjct 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS Sbjct 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC Sbjct 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ Sbjct 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL Sbjct 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP Sbjct 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR Sbjct 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT Sbjct 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 Query 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC Sbjct 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 >gi|148823551|ref|YP_001288305.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis F11] gi|253798576|ref|YP_003031577.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis KZN 1435] gi|289553863|ref|ZP_06443073.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis KZN 605] 9 more sequence titles Length=521 Score = 1044 bits (2699), Expect = 0.0, Method: Compositional matrix adjust. Identities = 512/512 (100%), Positives = 512/512 (100%), Gaps = 0/512 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF Sbjct 10 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 69 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS Sbjct 70 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 129 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC Sbjct 130 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 189 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ Sbjct 190 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 249 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL Sbjct 250 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 309 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP Sbjct 310 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 369 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR Sbjct 370 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 429 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT Sbjct 430 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 489 Query 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC Sbjct 490 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 521 >gi|308370983|ref|ZP_07423455.2| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu003] gi|308372210|ref|ZP_07427820.2| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu004] gi|308373387|ref|ZP_07432125.2| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu005] 9 more sequence titles Length=521 Score = 1042 bits (2694), Expect = 0.0, Method: Compositional matrix adjust. Identities = 511/512 (99%), Positives = 511/512 (99%), Gaps = 0/512 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF Sbjct 10 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 69 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS Sbjct 70 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 129 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC Sbjct 130 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 189 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ Sbjct 190 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 249 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL Sbjct 250 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 309 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP Sbjct 310 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 369 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR Sbjct 370 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 429 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPK PQCVPNAVLGT Sbjct 430 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKSPQCVPNAVLGT 489 Query 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC Sbjct 490 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 521 >gi|306780388|ref|ZP_07418725.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu002] gi|306968494|ref|ZP_07481155.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu009] gi|308326820|gb|EFP15671.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu002] gi|308353918|gb|EFP42769.1| membrane-associated phospholipase C 2 plcB [Mycobacterium tuberculosis SUMu009] Length=512 Score = 1042 bits (2694), Expect = 0.0, Method: Compositional matrix adjust. Identities = 511/512 (99%), Positives = 511/512 (99%), Gaps = 0/512 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF Sbjct 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS Sbjct 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC Sbjct 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ Sbjct 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL Sbjct 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP Sbjct 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR Sbjct 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPK PQCVPNAVLGT Sbjct 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKSPQCVPNAVLGT 480 Query 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC Sbjct 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 >gi|289745624|ref|ZP_06505002.1| phospholipase C 2 [Mycobacterium tuberculosis 02_1987] gi|289686152|gb|EFD53640.1| phospholipase C 2 [Mycobacterium tuberculosis 02_1987] Length=520 Score = 988 bits (2553), Expect = 0.0, Method: Compositional matrix adjust. Identities = 496/512 (97%), Positives = 499/512 (98%), Gaps = 0/512 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F K A A M A P+IEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF Sbjct 9 MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 68 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS Sbjct 69 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 128 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC Sbjct 129 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 188 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ Sbjct 189 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 248 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL Sbjct 249 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 308 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP Sbjct 309 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 368 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR Sbjct 369 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 428 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT Sbjct 429 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 488 Query 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC Sbjct 489 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 520 >gi|1399494|gb|AAC18944.1| phospholipase C [Mycobacterium tuberculosis H37Rv] Length=521 Score = 956 bits (2470), Expect = 0.0, Method: Compositional matrix adjust. Identities = 503/513 (99%), Positives = 505/513 (99%), Gaps = 2/513 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF Sbjct 10 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 69 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS Sbjct 70 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 129 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC Sbjct 130 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 189 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ Sbjct 190 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 249 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRL KVSWVL Sbjct 250 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLTKVSWVL 309 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP Sbjct 310 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 369 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGEFVTVPDIDSVPGSGGIRG IGLG RVPCL ISPY+ GPLMVHDTFDHTSTLKLIR Sbjct 370 GTPGEFVTVPDIDSVPGSGGIRGAIGLGPRVPCLFISPYT-GPLMVHDTFDHTSTLKLIR 428 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLN-ALPKLPQCVPNAVLG 479 ARFGVPVPNLTAWRDATVGD+TSTFNFAAPPNPSKPNLDHPR ALPKLPQCVPNAVLG Sbjct 429 ARFGVPVPNLTAWRDATVGDITSTFNFAAPPNPSKPNLDHPRAQCALPKLPQCVPNAVLG 488 Query 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC Sbjct 489 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 521 >gi|240173291|ref|ZP_04751949.1| membrane-associated phospholipase C 2 [Mycobacterium kansasii ATCC 12478] Length=510 Score = 877 bits (2265), Expect = 0.0, Method: Compositional matrix adjust. Identities = 443/512 (87%), Positives = 472/512 (93%), Gaps = 2/512 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 MTRRQFFAKAAAATTAGA SLA PIIEKAYGAGPC GHLTDIEHIVLLMQENRSFDHYF Sbjct 1 MTRRQFFAKAAAATTAGALTSLAAPIIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS TRGF+D +P FAQ GWNP TQAVDPAG T+P+RFDTTRGPL+ GECVNDPDH Sbjct 61 GTLSGTRGFNDPSP--AFAQKGWNPATQAVDPAGTTIPFRFDTTRGPLLDGECVNDPDHG 118 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI MHNSWNGGAND WLPAQ SPLQGNVPVTMG+YTRRDLPIHYLLADTFTVCD Y+C Sbjct 119 WIAMHNSWNGGANDGWLPAQAASSPLQGNVPVTMGYYTRRDLPIHYLLADTFTVCDAYYC 178 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGTTPNRLYWMSAWIDPDGT+GGP+LIEPNIQP Q SWRIMP+NLEDA VSWKVYQ Sbjct 179 SLLGGTTPNRLYWMSAWIDPDGTNGGPILIEPNIQPQQKLSWRIMPQNLEDAAVSWKVYQ 238 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NK LG LNNTVVGYNGL+NDF+QAADPRSNLAR+GI+PTYPLDFAADV+NN LPKVSWVL Sbjct 239 NKFLGPLNNTVVGYNGLINDFQQAADPRSNLARYGIAPTYPLDFAADVKNNALPKVSWVL 298 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 PGFLLSEHPA PV++GAV IVD LRILLSNPAVWEKTA+IVNYDENGGFFDHV PPTPPP Sbjct 299 PGFLLSEHPALPVSIGAVGIVDVLRILLSNPAVWEKTAVIVNYDENGGFFDHVTPPTPPP 358 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGE+VTVPDI++VPGSGGIRGPIGLGFR PC+VISPYSRGPLMVHDTFDHTSTLKLI Sbjct 359 GTPGEYVTVPDINAVPGSGGIRGPIGLGFRTPCIVISPYSRGPLMVHDTFDHTSTLKLIS 418 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVPVPNL+AWR+ VGDMTSTFNFA PPNPSKPNLDHP L ++PKLPQCVPNAVLGT Sbjct 419 ARFGVPVPNLSAWRNGVVGDMTSTFNFAVPPNPSKPNLDHPLLKSVPKLPQCVPNAVLGT 478 Query 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 TKT+IPYRVPFPQ MPTQET+PTRGIPSG+C Sbjct 479 TTKTSIPYRVPFPQMMPTQETSPTRGIPSGVC 510 >gi|183983797|ref|YP_001852088.1| membrane-associated phospholipase C 2 PlcB_1 [Mycobacterium marinum M] gi|183177123|gb|ACC42233.1| membrane-associated phospholipase C 2 PlcB_1 [Mycobacterium marinum M] Length=518 Score = 835 bits (2156), Expect = 0.0, Method: Compositional matrix adjust. Identities = 410/512 (81%), Positives = 454/512 (89%), Gaps = 2/512 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F AKAAAA+ AGAFMSLAGP+IEKAY AGPC GHL+DIEHIVL MQENRSFDHYF Sbjct 9 MSRREFLAKAAAASGAGAFMSLAGPVIEKAYAAGPCSGHLSDIEHIVLFMQENRSFDHYF 68 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 G LS T GFD +P +FAQ GWNP TQ+ DPAG T+PYRFDTTRGPLVAGECVNDP H Sbjct 69 GKLSGTNGFDSGSP--LFAQKGWNPQTQSNDPAGTTIPYRFDTTRGPLVAGECVNDPGHD 126 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI MHN+WN G NDNWLPAQ S LQGN PVTMG+Y R D+PIHYLLADTFT+CDGYFC Sbjct 127 WIAMHNAWNNGGNDNWLPAQAAVSALQGNTPVTMGYYQREDIPIHYLLADTFTICDGYFC 186 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SL+GGT+PNRLYWMS IDPDG +GGP+L++PNIQP +SWR MP+NLEDAGVSWK+YQ Sbjct 187 SLIGGTSPNRLYWMSGTIDPDGANGGPLLVDPNIQPQGRFSWRTMPDNLEDAGVSWKIYQ 246 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NKLLGALNNTV+GY+G++NDFKQA +PR+NLAR+GI+PTYP DF +DVRNNRLPKVSWVL Sbjct 247 NKLLGALNNTVIGYDGMLNDFKQAQNPRTNLARYGIAPTYPRDFVSDVRNNRLPKVSWVL 306 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 PGFLLSEHPAFPVNVGAVAIVD LRILLSNPAVWEKTALIV+YDENGGFFDHV P T PP Sbjct 307 PGFLLSEHPAFPVNVGAVAIVDVLRILLSNPAVWEKTALIVSYDENGGFFDHVTPTTAPP 366 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGE++TVP+ID+V GSGGIRGPIGLG+RVPC VISPYSRGPLMVHDTFDHTS LKLI Sbjct 367 GTPGEWITVPNIDAVTGSGGIRGPIGLGYRVPCFVISPYSRGPLMVHDTFDHTSQLKLIE 426 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 RFGVPVPN++AWR+ VGDMTSTFNFA PPN S+PNL HP +NA+ KLPQCVPN VLGT Sbjct 427 TRFGVPVPNISAWRNGLVGDMTSTFNFAVPPNSSRPNLSHPAINAVQKLPQCVPNYVLGT 486 Query 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 VTKTA+PYRVPFPQ MPTQET P RGIPSGLC Sbjct 487 VTKTAVPYRVPFPQVMPTQETQPARGIPSGLC 518 >gi|240173292|ref|ZP_04751950.1| membrane-associated phospholipase C 2 PlcB_4 [Mycobacterium kansasii ATCC 12478] Length=511 Score = 785 bits (2028), Expect = 0.0, Method: Compositional matrix adjust. Identities = 387/514 (76%), Positives = 438/514 (86%), Gaps = 5/514 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+FFAK A A M AGP+IEKAYGAGPC GHLTDIEHIVLLMQENRSFDHYF Sbjct 1 MSRREFFAKLTGAGAAALLMDFAGPVIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS TRGF+D +P + Q GWNPMTQA+DPAG+T+P+R DTTRGP++ GECVNDPDH+ Sbjct 61 GTLSSTRGFNDPSP--AYQQKGWNPMTQALDPAGITIPFRLDTTRGPILDGECVNDPDHA 118 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI MHNSWN G NDNWLPAQ + VP+ MG+YTR+D+PIH+LLADTFT+CDGY C Sbjct 119 WIAMHNSWNNGGNDNWLPAQSA-TRTGPYVPMVMGYYTRQDIPIHHLLADTFTICDGYHC 177 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGT PNRLYWMSA IDP GT+GGP L+EP P Q YSWRIMPENLEDAG+SWKVYQ Sbjct 178 SLLGGTLPNRLYWMSATIDPAGTNGGPQLVEPGFLPEQQYSWRIMPENLEDAGISWKVYQ 237 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +K G NT + NGLV F+Q+A+PRSNLARFGI+PTYPLDFAADV+ NRLP+VSW++ Sbjct 238 SKDAGRFINTPISNNGLVQAFRQSANPRSNLARFGIAPTYPLDFAADVKGNRLPQVSWLV 297 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P F+ SEHPA PV +GAVA+V+ALRILLSNPAVWEKTALI++YDENGGFFDHV PPT PP Sbjct 298 PPFIQSEHPALPVALGAVAMVNALRILLSNPAVWEKTALIISYDENGGFFDHVTPPTAPP 357 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGE+VTVPDI++V GSGGIRGPIGLGFRVPCLVISP+SRG LMVHDTFDHTS LKLIR Sbjct 358 GTPGEYVTVPDINAVTGSGGIRGPIGLGFRVPCLVISPFSRGGLMVHDTFDHTSQLKLIR 417 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVP+PNLTAWRD VGDMTS FNFA PPNP++PNL HP L A+PKLPQC+PN VLGT Sbjct 418 ARFGVPIPNLTAWRDGVVGDMTSAFNFATPPNPTRPNLSHPLLAAVPKLPQCIPNVVLGT 477 Query 481 VTKT--AIPYRVPFPQSMPTQETAPTRGIPSGLC 512 T AIPYRVP+PQ MPTQE++PTRGIPSGLC Sbjct 478 TDGTLPAIPYRVPYPQIMPTQESSPTRGIPSGLC 511 >gi|339298872|gb|AEJ50982.1| phospholipase C [Mycobacterium tuberculosis CCDC5180] Length=520 Score = 781 bits (2016), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/514 (76%), Positives = 430/514 (84%), Gaps = 5/514 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F K A A M A P+IEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF Sbjct 9 MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 68 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS T GF+ +P F Q GWNPMTQA+DPAGVT+P+R DTTRGP + GECVNDP+H Sbjct 69 GTLSSTNGFNAASP--AFQQMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQ 126 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 W+GMH +WNGGANDNWLPAQ + VP+TMG+YTR+D+PIHYLLADTFT+CDGY C Sbjct 127 WVGMHLAWNGGANDNWLPAQAT-TRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHC 185 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLL GT PNRLYW+SA IDP GTDGGP L+EP PLQ +SWRIMPENLEDAGVSWKVYQ Sbjct 186 SLLTGTLPNRLYWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQ 245 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NK LG NT + NGLV F+QAADPRSNLAR+GI+PTYP DFAADVR NRLPKVSW++ Sbjct 246 NKGLGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLV 305 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P L SEHPA PV +GAV++V ALRILLSNPAVWEKTALIV+YDENGGFFDHV PPT PP Sbjct 306 PNILQSEHPALPVALGAVSMVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPP 365 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGEFVTVP+ID+VPGSGGIRGP+GLGFRVPC+VISPYSRGPLMV DTFDHTS LKLIR Sbjct 366 GTPGEFVTVPNIDAVPGSGGIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIR 425 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVPVPN+TAWRD VGDMTS FNFAAPPN ++PNL HP L ALPKLPQC+PN VLGT Sbjct 426 ARFGVPVPNMTAWRDGVVGDMTSAFNFAAPPNSTRPNLSHPLLGALPKLPQCIPNVVLGT 485 Query 481 VTKT--AIPYRVPFPQSMPTQETAPTRGIPSGLC 512 +IPYRVP+PQ MPTQET P RG PSGLC Sbjct 486 TDGALPSIPYRVPYPQVMPTQETTPVRGTPSGLC 519 >gi|289758476|ref|ZP_06517854.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] gi|294994547|ref|ZP_06800238.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis 210] gi|289714040|gb|EFD78052.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] gi|326903967|gb|EGE50900.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis W-148] Length=512 Score = 780 bits (2015), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/514 (76%), Positives = 430/514 (84%), Gaps = 5/514 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F K A A M A P+IEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF Sbjct 1 MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS T GF+ +P F Q GWNPMTQA+DPAGVT+P+R DTTRGP + GECVNDP+H Sbjct 61 GTLSSTNGFNAASP--AFQQMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQ 118 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 W+GMH +WNGGANDNWLPAQ + VP+TMG+YTR+D+PIHYLLADTFT+CDGY C Sbjct 119 WVGMHLAWNGGANDNWLPAQAT-TRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHC 177 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLL GT PNRLYW+SA IDP GTDGGP L+EP PLQ +SWRIMPENLEDAGVSWKVYQ Sbjct 178 SLLTGTLPNRLYWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQ 237 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NK LG NT + NGLV F+QAADPRSNLAR+GI+PTYP DFAADVR NRLPKVSW++ Sbjct 238 NKGLGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLV 297 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P L SEHPA PV +GAV++V ALRILLSNPAVWEKTALIV+YDENGGFFDHV PPT PP Sbjct 298 PNILQSEHPALPVALGAVSMVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPP 357 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGEFVTVP+ID+VPGSGGIRGP+GLGFRVPC+VISPYSRGPLMV DTFDHTS LKLIR Sbjct 358 GTPGEFVTVPNIDAVPGSGGIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIR 417 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVPVPN+TAWRD VGDMTS FNFAAPPN ++PNL HP L ALPKLPQC+PN VLGT Sbjct 418 ARFGVPVPNMTAWRDGVVGDMTSAFNFAAPPNSTRPNLSHPLLGALPKLPQCIPNVVLGT 477 Query 481 VTKT--AIPYRVPFPQSMPTQETAPTRGIPSGLC 512 +IPYRVP+PQ MPTQET P RG PSGLC Sbjct 478 TDGALPSIPYRVPYPQVMPTQETTPVRGTPSGLC 511 >gi|15841858|ref|NP_336895.1| phospholipase C [Mycobacterium tuberculosis CDC1551] gi|148823552|ref|YP_001288306.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis F11] gi|253798575|ref|YP_003031576.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis KZN 1435] 33 more sequence titles Length=520 Score = 779 bits (2011), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/514 (76%), Positives = 429/514 (84%), Gaps = 5/514 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F K A A M A P+IEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF Sbjct 9 MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 68 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS T GF+ +P F Q GWNPMTQA+DPAGVT+P+R DTTRGP + GECVNDP+H Sbjct 69 GTLSSTNGFNAASP--AFQQMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQ 126 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 W+GMH +WNGGANDNWLPAQ + VP+TMG+YTR+D+PIHYLLADTFT+CDGY C Sbjct 127 WVGMHLAWNGGANDNWLPAQAT-TRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHC 185 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLL GT PNRLYW+SA IDP GTDGGP L+EP PLQ +SWRIMPENLEDAGVSWKVYQ Sbjct 186 SLLTGTLPNRLYWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQ 245 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NK LG NT + NGLV F+QAADPRSNLAR+GI+PTYP DFAADVR NRLPKVSW++ Sbjct 246 NKGLGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLV 305 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P L SEHPA PV +GAV++V ALRILLSNPAVWEKTALIV+YDENGGFFDHV PPT PP Sbjct 306 PNILQSEHPALPVALGAVSMVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPP 365 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGEFVTVP+ID+VPGSGGIRGP+GLGFRVPC+VISPYSRGPLMV DTFDHTS LKLIR Sbjct 366 GTPGEFVTVPNIDAVPGSGGIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIR 425 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVPVPN+TAWRD VGDMTS FNFA PPN ++PNL HP L ALPKLPQC+PN VLGT Sbjct 426 ARFGVPVPNMTAWRDGVVGDMTSAFNFATPPNSTRPNLSHPLLGALPKLPQCIPNVVLGT 485 Query 481 VTKT--AIPYRVPFPQSMPTQETAPTRGIPSGLC 512 +IPYRVP+PQ MPTQET P RG PSGLC Sbjct 486 TDGALPSIPYRVPYPQVMPTQETTPVRGTPSGLC 519 >gi|15609488|ref|NP_216867.1| membrane-associated phospholipase C [Mycobacterium tuberculosis H37Rv] gi|148662179|ref|YP_001283702.1| membrane-associated phospholipase C 1 [Mycobacterium tuberculosis H37Ra] gi|167969907|ref|ZP_02552184.1| membrane-associated phospholipase C 1 [Mycobacterium tuberculosis H37Ra] 18 more sequence titles Length=512 Score = 778 bits (2010), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/514 (76%), Positives = 429/514 (84%), Gaps = 5/514 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F K A A M A P+IEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF Sbjct 1 MSRREFLTKLTGAGAAAFLMDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS T GF+ +P F Q GWNPMTQA+DPAGVT+P+R DTTRGP + GECVNDP+H Sbjct 61 GTLSSTNGFNAASP--AFQQMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQ 118 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 W+GMH +WNGGANDNWLPAQ + VP+TMG+YTR+D+PIHYLLADTFT+CDGY C Sbjct 119 WVGMHLAWNGGANDNWLPAQAT-TRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHC 177 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLL GT PNRLYW+SA IDP GTDGGP L+EP PLQ +SWRIMPENLEDAGVSWKVYQ Sbjct 178 SLLTGTLPNRLYWLSANIDPAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQ 237 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NK LG NT + NGLV F+QAADPRSNLAR+GI+PTYP DFAADVR NRLPKVSW++ Sbjct 238 NKGLGRFINTPISNNGLVQAFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLV 297 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P L SEHPA PV +GAV++V ALRILLSNPAVWEKTALIV+YDENGGFFDHV PPT PP Sbjct 298 PNILQSEHPALPVALGAVSMVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPP 357 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGEFVTVP+ID+VPGSGGIRGP+GLGFRVPC+VISPYSRGPLMV DTFDHTS LKLIR Sbjct 358 GTPGEFVTVPNIDAVPGSGGIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIR 417 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 ARFGVPVPN+TAWRD VGDMTS FNFA PPN ++PNL HP L ALPKLPQC+PN VLGT Sbjct 418 ARFGVPVPNMTAWRDGVVGDMTSAFNFATPPNSTRPNLSHPLLGALPKLPQCIPNVVLGT 477 Query 481 VTKT--AIPYRVPFPQSMPTQETAPTRGIPSGLC 512 +IPYRVP+PQ MPTQET P RG PSGLC Sbjct 478 TDGALPSIPYRVPYPQVMPTQETTPVRGTPSGLC 511 >gi|183983547|ref|YP_001851838.1| membrane-associated phospholipase C 2 PlcB [Mycobacterium marinum M] gi|183176873|gb|ACC41983.1| membrane-associated phospholipase C 2 PlcB [Mycobacterium marinum M] Length=521 Score = 774 bits (1999), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/514 (74%), Positives = 431/514 (84%), Gaps = 5/514 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F AK AAA++AGA MSLAGP+IEKAYGAGPC GHLTDIEH V ++QENRSFDHYF Sbjct 11 MSRREFMAKLAAASSAGAMMSLAGPVIEKAYGAGPCSGHLTDIEHFVFMLQENRSFDHYF 70 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 G+LS GFD TP F Q GWNP TQ++DPAGVT+PYRFDTTRGPL+ G CVNDP H Sbjct 71 GSLSGINGFD--TPSSAFQQKGWNPQTQSIDPAGVTIPYRFDTTRGPLLNGACVNDPGHQ 128 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI MH ++N GANDNWL AQ LQGNVPVTMG+YTR+D PIHYLLADTFT+CDGY C Sbjct 129 WIDMHRAFNNGANDNWLGAQAQAQTLQGNVPVTMGYYTRQDQPIHYLLADTFTICDGYHC 188 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SL+GGT+PNRLYWMSAWIDP+G GGP+L++PNIQP +SWR MP+NL DAG+SWKVYQ Sbjct 189 SLIGGTSPNRLYWMSAWIDPNGEQGGPLLVDPNIQPQGRFSWRTMPDNLSDAGISWKVYQ 248 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NKLLGALNNTV+GY+G++NDF QA DPRSN+AR+GI+PTYPLDF ADV +NRLP+VSWVL Sbjct 249 NKLLGALNNTVIGYDGMLNDFVQARDPRSNMARYGIAPTYPLDFVADVASNRLPQVSWVL 308 Query 301 PGFLLSEHPAFPV--NVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTP 358 PGF +SEHP PV VG AIV+ LRILLSNPAVWEKTALIV++DENGGFFDHV P T Sbjct 309 PGFQVSEHPGVPVAPAVGGTAIVNILRILLSNPAVWEKTALIVSFDENGGFFDHVTPTTA 368 Query 359 PPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKL 418 P GTPGE++TVPDI++V GSGGIRGPIGLG+RVPC VISPYSRGPLMVHD FDHTS L+L Sbjct 369 PEGTPGEWITVPDINAVTGSGGIRGPIGLGYRVPCFVISPYSRGPLMVHDIFDHTSQLRL 428 Query 419 IRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVL 478 + RFGVPVPNLT WR GDMTSTFNFA PPN S PNLDHP L A+P+ QCVP+ V Sbjct 429 LEQRFGVPVPNLTTWRRGVTGDMTSTFNFAVPPNASPPNLDHPALKAVPQQVQCVPDTVT 488 Query 479 GTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 TKT PYRVPFPQ MP+QET+PTRGIPSG C Sbjct 489 -VFTKTVPPYRVPFPQVMPSQETSPTRGIPSGPC 521 >gi|118618235|ref|YP_906567.1| membrane-associated phospholipase C 2 PlcB [Mycobacterium ulcerans Agy99] gi|118570345|gb|ABL05096.1| membrane-associated phospholipase C 2 PlcB [Mycobacterium ulcerans Agy99] Length=511 Score = 771 bits (1992), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/514 (74%), Positives = 430/514 (84%), Gaps = 5/514 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F AK AAA++AGA MSLAGP+IEKAYGAGPC GHLTDIEH V ++QENRSFDHYF Sbjct 1 MSRREFMAKLAAASSAGAMMSLAGPVIEKAYGAGPCSGHLTDIEHFVFMLQENRSFDHYF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 G+LS GFD TP F Q GWNP TQ++DPAGVT+PYRFDTTRGPL+ G C NDP H Sbjct 61 GSLSGINGFD--TPSSAFQQKGWNPQTQSIDPAGVTIPYRFDTTRGPLLNGACANDPGHQ 118 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI MH ++N GANDNWL AQ LQGNVPVTMG+YTR+D PIHYLLADTFT+CDGY C Sbjct 119 WIDMHRAFNNGANDNWLGAQAQAQTLQGNVPVTMGYYTRQDQPIHYLLADTFTICDGYHC 178 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SL+GGT+PNRLYWMSAW+DP+G GGP+L++PNIQP +SWR MP+NL DAG+SWKVYQ Sbjct 179 SLIGGTSPNRLYWMSAWVDPNGEQGGPLLVDPNIQPQGRFSWRTMPDNLSDAGISWKVYQ 238 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NKLLGALNNTV+GY+G++NDF QA DPRSN+AR+GI+PTYPLDF ADV +NRLP+VSWVL Sbjct 239 NKLLGALNNTVIGYDGMLNDFVQARDPRSNMARYGIAPTYPLDFVADVASNRLPQVSWVL 298 Query 301 PGFLLSEHPAFPV--NVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTP 358 PGF +SEHP PV VG AIV+ LRILLSNPAVWEKTALIV++DENGGFFDHV P T Sbjct 299 PGFQVSEHPGVPVAPAVGGTAIVNILRILLSNPAVWEKTALIVSFDENGGFFDHVTPTTA 358 Query 359 PPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKL 418 P GTPGE++TVPDI++V GSGGIRGPIGLG+RVPC VISPYSRGPLMVHD FDHTS L+L Sbjct 359 PEGTPGEWITVPDINAVTGSGGIRGPIGLGYRVPCFVISPYSRGPLMVHDIFDHTSQLRL 418 Query 419 IRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVL 478 + RFGVPVPNLT WR GDMTSTFNFA PPN S PNLDHP L A+P+ QCVP+ V Sbjct 419 LEQRFGVPVPNLTTWRRGVTGDMTSTFNFAVPPNASPPNLDHPALKAVPQQVQCVPDTVT 478 Query 479 GTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 TKT PYRVPFPQ MP+QET+PTRGIPSG C Sbjct 479 -VFTKTVPPYRVPFPQVMPSQETSPTRGIPSGPC 511 >gi|183983637|ref|YP_001851928.1| membrane-associated phospholipase C 2 PlcB_4 [Mycobacterium marinum M] gi|183176963|gb|ACC42073.1| membrane-associated phospholipase C 2 PlcB_4 [Mycobacterium marinum M] Length=520 Score = 764 bits (1974), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/514 (75%), Positives = 423/514 (83%), Gaps = 5/514 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F AK A A M AGP+IEKAYGAGPC G LTDIEHIVLLMQENRSFDHYF Sbjct 9 MSRREFIAKMTGAGAAALLMDYAGPVIEKAYGAGPCSGQLTDIEHIVLLMQENRSFDHYF 68 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS RGF D +P F Q GWNP TQA+DPAG T+P+R DTTRGP + GECVNDP+H Sbjct 69 GTLSSIRGFSDPSP--AFQQKGWNPRTQALDPAGTTIPFRLDTTRGPFLDGECVNDPEHQ 126 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 W MH SWNGGANDNWLPAQ + VP+TMG+YTR+D+PIH+LLADTFT+CDGY C Sbjct 127 WTAMHLSWNGGANDNWLPAQAN-TRTGPYVPMTMGYYTRQDIPIHHLLADTFTICDGYHC 185 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLL GT PNRLYWMSAW DP GT+GGP L+EP PL YSWRIMPENLEDAGVSWKVYQ Sbjct 186 SLLTGTLPNRLYWMSAWNDPAGTNGGPQLVEPGFLPLHQYSWRIMPENLEDAGVSWKVYQ 245 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NK G NT + NGLV FKQ+ DPRSNLAR+GI+P YP+DFAADV+ NRLPKVSW++ Sbjct 246 NKDAGRFINTPISNNGLVQAFKQSGDPRSNLARYGIAPGYPVDFAADVKANRLPKVSWLV 305 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P FL SEHPA PV +GAVA+V ALRILLSNPAVWEKTALI++YDENGGFFDHV PPT PP Sbjct 306 PNFLQSEHPALPVALGAVAMVTALRILLSNPAVWEKTALIISYDENGGFFDHVTPPTAPP 365 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGE+VTVPDI+SVPGSGGIRGP+GLGFRVPC+V+SP+SRG LMVHD FDHTS LKLI Sbjct 366 GTPGEWVTVPDINSVPGSGGIRGPLGLGFRVPCIVVSPFSRGGLMVHDIFDHTSQLKLIS 425 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 RF VPVPNLTAWRD VGDMTSTFNFA PPNPS+PNL HP L A+PKLPQC+PN VLGT Sbjct 426 KRFDVPVPNLTAWRDGVVGDMTSTFNFATPPNPSRPNLSHPLLAAVPKLPQCIPNVVLGT 485 Query 481 VTKT--AIPYRVPFPQSMPTQETAPTRGIPSGLC 512 T AIPYRVP+PQSMP QE+ P RG+PSGLC Sbjct 486 SDGTFPAIPYRVPYPQSMPGQESTPVRGVPSGLC 519 >gi|339295253|gb|AEJ47364.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis CCDC5079] Length=493 Score = 764 bits (1974), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/495 (78%), Positives = 421/495 (86%), Gaps = 5/495 (1%) Query 20 MSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYFGTLSDTRGFDDTTPPVVFA 79 M A P+IEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYFGTLS T GF+ +P F Sbjct 1 MDWAAPVIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYFGTLSSTNGFNAASP--AFQ 58 Query 80 QSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHSWIGMHNSWNGGANDNWLPA 139 Q GWNPMTQA+DPAGVT+P+R DTTRGP + GECVNDP+H W+GMH +WNGGANDNWLPA Sbjct 59 QMGWNPMTQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQWVGMHLAWNGGANDNWLPA 118 Query 140 QVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFCSLLGGTTPNRLYWMSAWID 199 Q + VP+TMG+YTR+D+PIHYLLADTFT+CDGY CSLL GT PNRLYW+SA ID Sbjct 119 QAT-TRAGPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLLTGTLPNRLYWLSANID 177 Query 200 PDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQNKLLGALNNTVVGYNGLVN 259 P GTDGGP L+EP PLQ +SWRIMPENLEDAGVSWKVYQNK LG NT + NGLV Sbjct 178 PAGTDGGPQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQNKGLGRFINTPISNNGLVQ 237 Query 260 DFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVA 319 F+QAADPRSNLAR+GI+PTYP DFAADVR NRLPKVSW++P L SEHPA PV +GAV+ Sbjct 238 AFRQAADPRSNLARYGIAPTYPGDFAADVRANRLPKVSWLVPNILQSEHPALPVALGAVS 297 Query 320 IVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSG 379 +V ALRILLSNPAVWEKTALIV+YDENGGFFDHV PPT PPGTPGEFVTVP+ID+VPGSG Sbjct 298 MVTALRILLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPPGTPGEFVTVPNIDAVPGSG 357 Query 380 GIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVG 439 GIRGP+GLGFRVPC+VISPYSRGPLMV DTFDHTS LKLIRARFGVPVPN+TAWRD VG Sbjct 358 GIRGPLGLGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIRARFGVPVPNMTAWRDGVVG 417 Query 440 DMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKT--AIPYRVPFPQSMP 497 DMTS FNFAAPPN ++PNL HP L ALPKLPQC+PN VLGT +IPYRVP+PQ MP Sbjct 418 DMTSAFNFAAPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTDGALPSIPYRVPYPQVMP 477 Query 498 TQETAPTRGIPSGLC 512 TQET P RG PSGLC Sbjct 478 TQETTPVRGTPSGLC 492 >gi|240169308|ref|ZP_04747967.1| membrane-associated phospholipase C 2 PlcB [Mycobacterium kansasii ATCC 12478] Length=511 Score = 764 bits (1974), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/514 (75%), Positives = 431/514 (84%), Gaps = 5/514 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F A+ A A +AGA MSLAGP+IE+AYGAGPC GHLTDIEH VL++QENRSFDH+F Sbjct 1 MSRREFMARIATAGSAGALMSLAGPVIERAYGAGPCSGHLTDIEHFVLMLQENRSFDHFF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS GFD TP F Q GWNP TQ++DPAGVT+PYRFDTTRGP++ G CVNDP H Sbjct 61 GTLSGINGFD--TPSPSFQQKGWNPQTQSIDPAGVTIPYRFDTTRGPVLNGACVNDPAHQ 118 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI +H SWN GANDNWLPAQ LQGNVPV+MG+YTR+D PIHYLLADTFT+CDGY+C Sbjct 119 WITIHKSWNNGANDNWLPAQAEQQTLQGNVPVSMGYYTRQDQPIHYLLADTFTICDGYYC 178 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGT+PNRLYW+SAWIDPDG GGP+LI+PNIQP +SWR MP+NL DAG+SWKVYQ Sbjct 179 SLLGGTSPNRLYWISAWIDPDGVAGGPLLIDPNIQPQAQFSWRTMPDNLSDAGISWKVYQ 238 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NKLLGALNNTV+GYNG++ DFKQA DPRSN+AR GI+PTYPLDF ADV NRLP+VSWVL Sbjct 239 NKLLGALNNTVIGYNGMLVDFKQAQDPRSNIARNGIAPTYPLDFVADVAANRLPQVSWVL 298 Query 301 PGFLLSEHPAFPVN--VGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTP 358 PGF +SEHP PV VG AIV+ LRILLSNP VWEKTALIV++DENGGFFDHV PPT Sbjct 299 PGFQVSEHPGLPVTPAVGGTAIVNILRILLSNPQVWEKTALIVSFDENGGFFDHVTPPTA 358 Query 359 PPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKL 418 PPGTPGE+VTVPDID+V GSGGIRGPIGLG+RVPC +ISPYSRGPLMVHDTFDHTS L+L Sbjct 359 PPGTPGEYVTVPDIDAVTGSGGIRGPIGLGYRVPCFIISPYSRGPLMVHDTFDHTSQLRL 418 Query 419 IRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVL 478 + RFGVPVPNL+AWR + GDMTSTFNFA PPNP+ PNLDHP L A+P QCVP+ V Sbjct 419 LEKRFGVPVPNLSAWRRSVTGDMTSTFNFAVPPNPAPPNLDHPALQAIPPQVQCVPDTV- 477 Query 479 GTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 T K PYRVPFPQ MPTQET P RGIPSG C Sbjct 478 ATFAKVTPPYRVPFPQVMPTQETTPARGIPSGPC 511 >gi|183980315|ref|YP_001848606.1| membrane-associated phospholipase C 2 PlcB_3 [Mycobacterium marinum M] gi|183173641|gb|ACC38751.1| membrane-associated phospholipase C 2 PlcB_3 [Mycobacterium marinum M] Length=580 Score = 750 bits (1937), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/515 (74%), Positives = 430/515 (84%), Gaps = 5/515 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RRQF AK AAA++AGA MSLAGP+IEKAYGAGPC GHLTDIEHIVLLMQENRSFDHYF Sbjct 68 MSRRQFMAKLAAASSAGALMSLAGPVIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYF 127 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS RGFDDTT P +F Q GW+P TQ++DPAG+T P+RFDTTRGPL+ GECVNDP Sbjct 128 GTLSGVRGFDDTTDPAIFDQKGWDPRTQSIDPAGITSPFRFDTTRGPLLNGECVNDPVEG 187 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPL-QGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYF 179 W+ MH +WN GAND WLP+Q +S + QGN+P MG+YTR DLPIHY+LADTFT+CD Y+ Sbjct 188 WVAMHTAWNNGANDTWLPSQ--YSQIRQGNIPACMGYYTRADLPIHYMLADTFTICDDYY 245 Query 180 CSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVY 239 CS+L GT PNRLYW+SAWIDPDGT+GGP+L EPN PLQ +SWRIMPENLEDAG+SWKVY Sbjct 246 CSMLTGTAPNRLYWLSAWIDPDGTNGGPLLNEPNFLPLQPFSWRIMPENLEDAGISWKVY 305 Query 240 QNKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWV 299 QNK G N+ + NGLV FKQ ADPRSNLARFGI+PTYP DF DV+ NRLPKVSWV Sbjct 306 QNKFFGHYINSPISDNGLVQAFKQTADPRSNLARFGIAPTYPQDFVLDVKANRLPKVSWV 365 Query 300 LPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPP 359 +P + SEHPA PVNVGAVAIV+ LR LLSNPAVWEKTALI++YDE G FFDHV PPT P Sbjct 366 VPNIIQSEHPALPVNVGAVAIVNILRTLLSNPAVWEKTALIISYDECGSFFDHVTPPTAP 425 Query 360 PGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 PGTPGE+VTVPDID+V GSGGIRGPIGLG+RVPC+VISPYSRGPL+V DTFDHTS L+LI Sbjct 426 PGTPGEYVTVPDIDAVSGSGGIRGPIGLGYRVPCIVISPYSRGPLVVSDTFDHTSQLRLI 485 Query 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 479 RFGVPVPNLT WR + DMTS FNFA PPNPS+P LD P LNALP+LPQCVPNAVLG Sbjct 486 ETRFGVPVPNLTPWRRSVTEDMTSAFNFAVPPNPSRPKLDPPLLNALPRLPQCVPNAVLG 545 Query 480 TVTKTAI--PYRVPFPQSMPTQETAPTRGIPSGLC 512 ++ A+ PYRVP+PQ PTQET P RG PSG C Sbjct 546 SLGGAAVANPYRVPYPQVPPTQETTPARGTPSGPC 580 >gi|254232495|ref|ZP_04925822.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis C] gi|124601554|gb|EAY60564.1| membrane-associated phospholipase C 1 plcA [Mycobacterium tuberculosis C] Length=486 Score = 743 bits (1918), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/488 (77%), Positives = 412/488 (85%), Gaps = 5/488 (1%) Query 27 IEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYFGTLSDTRGFDDTTPPVVFAQSGWNPM 86 +++ GPCPGHLTDIEHIVLLMQENRSFDHYFGTLS T GF+ +P F Q GWNPM Sbjct 1 MKRPTAPGPCPGHLTDIEHIVLLMQENRSFDHYFGTLSSTNGFNAASP--AFQQMGWNPM 58 Query 87 TQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHSWIGMHNSWNGGANDNWLPAQVPFSPL 146 TQA+DPAGVT+P+R DTTRGP + GECVNDP+H W+GMH +WNGGANDNWLPAQ + Sbjct 59 TQALDPAGVTIPFRLDTTRGPFLDGECVNDPEHQWVGMHLAWNGGANDNWLPAQA-TTRA 117 Query 147 QGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFCSLLGGTTPNRLYWMSAWIDPDGTDGG 206 VP+TMG+YTR+D+PIHYLLADTFT+CDGY CSLL GT PNRLYW+SA IDP GTDGG Sbjct 118 GPYVPLTMGYYTRQDIPIHYLLADTFTICDGYHCSLLTGTLPNRLYWLSANIDPAGTDGG 177 Query 207 PVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQNKLLGALNNTVVGYNGLVNDFKQAAD 266 P L+EP PLQ +SWRIMPENLEDAGVSWKVYQNK LG NT + NGLV F+QAAD Sbjct 178 PQLVEPGFLPLQQFSWRIMPENLEDAGVSWKVYQNKGLGRFINTPISNNGLVQAFRQAAD 237 Query 267 PRSNLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRI 326 PRSNLAR+GI+PTYP DFAADVR NRLPKVSW++P L SEHPA PV +GAV++V ALRI Sbjct 238 PRSNLARYGIAPTYPGDFAADVRANRLPKVSWLVPNILQSEHPALPVALGAVSMVTALRI 297 Query 327 LLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPIG 386 LLSNPAVWEKTALIV+YDENGGFFDHV PPT PPGTPGEFVTVP+ID+VPGSGGIRGP+G Sbjct 298 LLSNPAVWEKTALIVSYDENGGFFDHVTPPTAPPGTPGEFVTVPNIDAVPGSGGIRGPLG 357 Query 387 LGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTFN 446 LGFRVPC+VISPYSRGPLMV DTFDHTS LKLIRARFGVPVPN+TAWRD VGDMTS FN Sbjct 358 LGFRVPCIVISPYSRGPLMVSDTFDHTSQLKLIRARFGVPVPNMTAWRDGVVGDMTSAFN 417 Query 447 FAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKT--AIPYRVPFPQSMPTQETAPT 504 FA PPN ++PNL HP L ALPKLPQC+PN VLGT +IPYRVP+PQ MPTQET P Sbjct 418 FATPPNSTRPNLSHPLLGALPKLPQCIPNVVLGTTDGALPSIPYRVPYPQVMPTQETTPV 477 Query 505 RGIPSGLC 512 RG PSGLC Sbjct 478 RGTPSGLC 485 >gi|308380173|ref|ZP_07669139.1| putative Tat (twin-arginine translocation) pathway signal sequence containing protein [Mycobacterium tuberculosis SUMu011] gi|339631808|ref|YP_004723450.1| phospholipase C [Mycobacterium africanum GM041182] gi|308362387|gb|EFP51238.1| putative Tat (twin-arginine translocation) pathway signal sequence containing protein [Mycobacterium tuberculosis SUMu011] gi|339331164|emb|CCC26844.1| putative phospholipase C 4 PLCD [Mycobacterium africanum GM041182] Length=525 Score = 734 bits (1895), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/512 (72%), Positives = 411/512 (81%), Gaps = 6/512 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 ++RR+F AK AA A MS AGP+IEKAYGAGPC GHLTDIEH V MQENRSFDHYF Sbjct 20 VSRREFLAKVAAGGAG-ALMSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYF 78 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS T GF+ +P +F Q GWNPMTQA+D GVT+PYRFDTTRGP + G CVNDPDHS Sbjct 79 GTLSGTDGFNTVSP--LFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHS 136 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 W+ MH SWNGG NDNWLPAQ + + P MG+YTR+D+PIHYLLAD FTVCD YFC Sbjct 137 WVAMHESWNGGVNDNWLPAQAK-TRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFC 195 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 S+LG T PNRLYW+SA IDPDG +GGP L P QP++ + WRIMP+NL DAGVSWKVY+ Sbjct 196 SVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYR 255 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NK LG ++ +V+ Y LV FKQ+ADPRS+L RFG++P+YP FAADV NRLP+VSWV+ Sbjct 256 NKTLGPIS-SVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVI 314 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P L SEHPA P GA AIV+ LRILL+NPAVWEKTALIV+YDENGGFFDHVVP T P Sbjct 315 PNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPA 374 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGE+VTVPDID VPGSGGIRGPIGLGFRVPC VISPYSRGP MVHDTFDHTS L+L+ Sbjct 375 GTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLE 434 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 RFGVPVPNLTAWR + GDMTSTFNFA PPN S PNLD+P L+AL +PQCVPNA LGT Sbjct 435 TRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGT 494 Query 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 + + IPYRVP PQ MPTQET PTRGIPSG C Sbjct 495 INR-GIPYRVPDPQIMPTQETTPTRGIPSGPC 525 >gi|15841221|ref|NP_336258.1| phospholipase C [Mycobacterium tuberculosis CDC1551] gi|31792943|ref|NP_855436.1| phospholipase C 4 PLCD [Mycobacterium bovis AF2122/97] gi|121637663|ref|YP_977886.1| putative phospholipase C 4 plcD [Mycobacterium bovis BCG str. Pasteur 1173P2] 28 more sequence titles Length=514 Score = 733 bits (1891), Expect = 0.0, Method: Compositional matrix adjust. Identities = 364/512 (72%), Positives = 411/512 (81%), Gaps = 6/512 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 ++RR+F AK AA A MS AGP+IEKAYGAGPC GHLTDIEH V MQENRSFDHYF Sbjct 9 VSRREFLAKVAAGGAG-ALMSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYF 67 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS T GF+ +P +F Q GWNPMTQA+D GVT+PYRFDTTRGP + G CVNDPDHS Sbjct 68 GTLSGTDGFNTVSP--LFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHS 125 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 W+ MH SWNGG NDNWLPAQ + + P MG+YTR+D+PIHYLLAD FTVCD YFC Sbjct 126 WVAMHESWNGGVNDNWLPAQAK-TRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFC 184 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 S+LG T PNRLYW+SA IDPDG +GGP L P QP++ + WRIMP+NL DAGVSWKVY+ Sbjct 185 SVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYR 244 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NK LG ++ +V+ Y LV FKQ+ADPRS+L RFG++P+YP FAADV NRLP+VSWV+ Sbjct 245 NKTLGPIS-SVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVI 303 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P L SEHPA P GA AIV+ LRILL+NPAVWEKTALIV+YDENGGFFDHVVP T P Sbjct 304 PNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPA 363 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGE+VTVPDID VPGSGGIRGPIGLGFRVPC VISPYSRGP MVHDTFDHTS L+L+ Sbjct 364 GTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLE 423 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 RFGVPVPNLTAWR + GDMTSTFNFA PPN S PNLD+P L+AL +PQCVPNA LGT Sbjct 424 TRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGT 483 Query 481 VTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 + + IPYRVP PQ MPTQET PTRGIPSG C Sbjct 484 INR-GIPYRVPDPQIMPTQETTPTRGIPSGPC 514 >gi|240170410|ref|ZP_04749069.1| membrane-associated phospholipase C 2 PlcB_6 [Mycobacterium kansasii ATCC 12478] Length=517 Score = 727 bits (1876), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/515 (71%), Positives = 415/515 (81%), Gaps = 9/515 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 MTRR+F AKAAAATTA + MSL GP+IEKAYGAGPC G LTDIEHIVLLMQENRSFDHYF Sbjct 9 MTRREFLAKAAAATTAASLMSLVGPVIEKAYGAGPCSGQLTDIEHIVLLMQENRSFDHYF 68 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLSD GFD +P +F Q GW+P TQ++DP+G+TLP+RFDTTR P + G C+NDPDH Sbjct 69 GTLSDIDGFDTASP--LFQQKGWDPRTQSLDPSGITLPFRFDTTRAPFLNGACINDPDHD 126 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI +H SWNGGANDNWLPAQ + N P TMG++TRRD+PIHYLLADTFTVCD YFC Sbjct 127 WIAIHQSWNGGANDNWLPAQA-RTRSAANTPATMGYHTRRDIPIHYLLADTFTVCDHYFC 185 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 S+LG T+PNRLYW+SAWIDP GT+GGP++ + P+ ++WRIMP+NL DAGVSWKVY Sbjct 186 SVLGPTSPNRLYWLSAWIDPAGTNGGPLVETSSTAPIGAFNWRIMPQNLSDAGVSWKVYS 245 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +K LG N VGY +V FKQAADPRS+LARFG++P YP DFAADVR NRLP+VSW++ Sbjct 246 DKSLGPAVNAYVGYGEIVRWFKQAADPRSDLARFGVAPRYPWDFAADVRANRLPQVSWLV 305 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P L+SEHPA P GAVA+ D LRILLSNPAVWEKTALIV+YDENGGFFDHVVPPT PP Sbjct 306 PNILVSEHPAMPDAGGAVAMADTLRILLSNPAVWEKTALIVSYDENGGFFDHVVPPTAPP 365 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GT GE++TVPDID V GSGGIRGPIGLGFRVPCLVISP+SRG LM HD FDHTS L+LI Sbjct 366 GTAGEYLTVPDIDGVAGSGGIRGPIGLGFRVPCLVISPFSRGGLMAHDVFDHTSQLRLIE 425 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGT 480 RFGVPVPNLTAWR + GDMTS FNFA PPNPS P L+ R LP+L QC +G Sbjct 426 KRFGVPVPNLTAWRRSVTGDMTSAFNFAVPPNPSPPKLNQSR-RVLPELAQC--GLGIGA 482 Query 481 VTKTAI---PYRVPFPQSMPTQETAPTRGIPSGLC 512 +T T PYRVP+PQ+MP+QET PTRGIPSGLC Sbjct 483 LTGTYRLNPPYRVPYPQAMPSQETTPTRGIPSGLC 517 >gi|254231948|ref|ZP_04925275.1| phospholipase C 4 (fragment) plcD [Mycobacterium tuberculosis C] gi|124601007|gb|EAY60017.1| phospholipase C 4 (fragment) plcD [Mycobacterium tuberculosis C] Length=488 Score = 724 bits (1870), Expect = 0.0, Method: Compositional matrix adjust. Identities = 356/493 (73%), Positives = 400/493 (82%), Gaps = 5/493 (1%) Query 20 MSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYFGTLSDTRGFDDTTPPVVFA 79 MS AGP+IEKAYGAGPC GHLTDIEH V MQENRSFDHYFGTLS T GF+ +P +F Sbjct 1 MSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYFGTLSGTDGFNTVSP--LFQ 58 Query 80 QSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHSWIGMHNSWNGGANDNWLPA 139 Q GWNPMTQA+D GVT+PYRFDTTRGP + G CVNDPDHSW+ MH SWNGG NDNWLPA Sbjct 59 QKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHSWVAMHESWNGGVNDNWLPA 118 Query 140 QVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFCSLLGGTTPNRLYWMSAWID 199 Q + + P MG+YTR+D+PIHYLLAD FTVCD YFCS+LG T PNRLYW+SA ID Sbjct 119 QAK-TRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNRLYWLSATID 177 Query 200 PDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQNKLLGALNNTVVGYNGLVN 259 PDG +GGP L P QP++ + WRIMP+NL DAGVSWKVY+NK LG ++ +V+ Y LV Sbjct 178 PDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYRNKTLGPIS-SVLTYGSLVT 236 Query 260 DFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVA 319 FKQ+ADPRS+L RFG++P+YP FAADV NRLP+VSWV+P L SEHPA P GA A Sbjct 237 SFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVIPNVLESEHPAVPAAAGAFA 296 Query 320 IVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSG 379 IV+ LRILL+NPAVWEKTALIV+YDENGGFFDHVVP T P GTPGE+VTVPDID VPGSG Sbjct 297 IVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPAGTPGEYVTVPDIDQVPGSG 356 Query 380 GIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVG 439 GIRGPIGLGFRVPC VISPYSRGP MVHDTFDHTS L+L+ RFGVPVPNLTAWR + G Sbjct 357 GIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSVTG 416 Query 440 DMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKTAIPYRVPFPQSMPTQ 499 DMTSTFNFA PPN S PNLD+P L+AL +PQCVPNA LGT+ + IPYRVP PQ MPTQ Sbjct 417 DMTSTFNFAVPPNSSWPNLDYPGLHALSTVPQCVPNAALGTINR-GIPYRVPDPQIMPTQ 475 Query 500 ETAPTRGIPSGLC 512 ET PTRGIPSG C Sbjct 476 ETTPTRGIPSGPC 488 >gi|183981500|ref|YP_001849791.1| membrane-associated phospholipase C 2 PlcB_2 [Mycobacterium marinum M] gi|183174826|gb|ACC39936.1| membrane-associated phospholipase C 2 PlcB_2 [Mycobacterium marinum M] Length=528 Score = 723 bits (1867), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/525 (70%), Positives = 413/525 (79%), Gaps = 16/525 (3%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F AKAAA A MS AGP+IEKAYGAGPC GHL+DIEH V + ENRSFDHYF Sbjct 7 MSRRKFLAKAAAGGAG-ALMSFAGPVIEKAYGAGPCSGHLSDIEHFVFFLMENRSFDHYF 65 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS T GFD +P +F Q GWNP TQ +DPAG+T+PYRFDTTRGP V GEC++DPDHS Sbjct 66 GTLSATDGFDSGSP--LFQQKGWNPQTQTIDPAGITMPYRFDTTRGPFVDGECLSDPDHS 123 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPL--QGNVPVTMGFYTRRDLPIHYLLADTFTVCDGY 178 W MH SWNGGANDNWLPAQV SP+ GNVPVTMG+ TR+D+PIHYLLADTFTVCD Y Sbjct 124 WEAMHKSWNGGANDNWLPAQVGHSPVPNGGNVPVTMGYLTRKDIPIHYLLADTFTVCDRY 183 Query 179 FCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKV 238 F S+LG T PNRLYW+SA + DGT GGP L P P+ +SW MPENL AG+SWK+ Sbjct 184 FSSVLGPTLPNRLYWLSASLGADGTQGGPQLTSPPTDPIGRFSWTTMPENLSAAGISWKL 243 Query 239 YQNKLLGALNNTVVGY--NGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKV 296 Y+NK LG + N Y + +V FKQA DPRS LARFG++PTYP +F ADV+ NRLP+V Sbjct 244 YRNKTLGPVLNQYFNYTYDDIVMFFKQAQDPRSELARFGMAPTYPFEFMADVKANRLPQV 303 Query 297 SWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPP 356 SWV+P SEHPAFP VGAVAIV+ LRILLSNPAVWEKTALIV YDENGGFFDHVVPP Sbjct 304 SWVVPNTPQSEHPAFPPAVGAVAIVNLLRILLSNPAVWEKTALIVGYDENGGFFDHVVPP 363 Query 357 TPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTL 416 T P GTPGE++TVPDI+SV G+GGIRGPIGLG+RVP +VISP+SRG LMVHD FDHTS L Sbjct 364 TAPEGTPGEYLTVPDINSVSGAGGIRGPIGLGYRVPGIVISPFSRGGLMVHDVFDHTSQL 423 Query 417 KLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNA 476 KLI RF VPVPNLT WRD+TVGDMTS FNFA PPNPS+P+L HP L ALPKLPQC+PN Sbjct 424 KLISKRFSVPVPNLTPWRDSTVGDMTSAFNFAVPPNPSRPSLSHPGLAALPKLPQCIPNV 483 Query 477 VLGTV---------TKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 LGTV + IPYRVPFPQS+P+QET P RGIPSG C Sbjct 484 WLGTVGVNPNPYTGSPQGIPYRVPFPQSLPSQETTPARGIPSGPC 528 >gi|254551397|ref|ZP_05141844.1| phospholipase C 3 plcC [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] gi|308370982|ref|ZP_07423454.2| phospholipase C 3 plcC [Mycobacterium tuberculosis SUMu003] gi|308373386|ref|ZP_07432124.2| phospholipase C 3 plcC [Mycobacterium tuberculosis SUMu005] gi|313659273|ref|ZP_07816153.1| phospholipase C 3 plcC [Mycobacterium tuberculosis KZN V2475] gi|18202462|sp|P95245.2|PHLC_MYCTU RecName: Full=Phospholipase C 3; Flags: Precursor gi|308330338|gb|EFP19189.1| phospholipase C 3 plcC [Mycobacterium tuberculosis SUMu003] gi|308337815|gb|EFP26666.1| phospholipase C 3 plcC [Mycobacterium tuberculosis SUMu005] Length=517 Score = 693 bits (1788), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/513 (68%), Positives = 397/513 (78%), Gaps = 6/513 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 10 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 69 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 70 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 127 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 128 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 186 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 187 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 246 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 247 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 306 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 307 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 366 Query 361 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 GTPGE++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 367 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 426 Query 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 479 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG Sbjct 427 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 485 Query 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 486 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 517 >gi|148823550|ref|YP_001288304.1| phospholipase C 3 plcC [Mycobacterium tuberculosis F11] gi|167969905|ref|ZP_02552182.1| phospholipase C 3 plcC [Mycobacterium tuberculosis H37Ra] gi|253798577|ref|YP_003031578.1| phospholipase C 3 plcC [Mycobacterium tuberculosis KZN 1435] 23 more sequence titles Length=516 Score = 692 bits (1787), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/513 (68%), Positives = 397/513 (78%), Gaps = 6/513 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 9 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 68 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 69 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 126 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 127 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 185 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 186 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 245 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 246 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 305 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 306 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 365 Query 361 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 GTPGE++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 366 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 425 Query 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 479 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG Sbjct 426 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 484 Query 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 485 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 516 >gi|183984690|ref|YP_001852981.1| membrane-associated phospholipase C 2 PlcB_6 [Mycobacterium marinum M] gi|183178016|gb|ACC43126.1| membrane-associated phospholipase C 2 PlcB_6 [Mycobacterium marinum M] Length=518 Score = 692 bits (1787), Expect = 0.0, Method: Compositional matrix adjust. Identities = 349/513 (69%), Positives = 405/513 (79%), Gaps = 5/513 (0%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F AK AAAT+ GA MSLAGP+IEKAYGAGPC GHLTDIEHIVLLMQENRSFDHYF Sbjct 10 MSRREFLAKLAAATSTGALMSLAGPVIEKAYGAGPCSGHLTDIEHIVLLMQENRSFDHYF 69 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLSD GFD TP +FAQ GWNP TQA DPA TLP+R DTTR PL+ G CVNDPDH Sbjct 70 GTLSDVEGFDTPTP--LFAQKGWNPRTQAPDPASTTLPFRLDTTRPPLLNGACVNDPDHG 127 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 W +H+SWNGGANDNWLPAQ + N+P T+G++TR DLPIH+LLADTFTVCD YFC Sbjct 128 WATLHDSWNGGANDNWLPAQA-RTRSAANIPATLGYHTRDDLPIHFLLADTFTVCDHYFC 186 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 S++G T PNRLYW+SAW+DPDG +GGP++ P+ +SW IMP++L DAGVSWK+Y Sbjct 187 SVIGPTFPNRLYWVSAWLDPDGANGGPLVETIPTPPIGKFSWPIMPQHLSDAGVSWKIYY 246 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +K LG N+ VGY +V F QA DPRS+L RFG +P YP DFA DV+ NRLP+VSW++ Sbjct 247 DKRLGPAVNSYVGYGEIVRWFTQAQDPRSDLVRFGATPRYPRDFATDVKANRLPQVSWLI 306 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P FL SEHPA P GA+A +D LRILLSNPAVWEKTALIV+YDENGGFFDHVVPPTPP Sbjct 307 PNFLESEHPAMPNAGGAIAFMDVLRILLSNPAVWEKTALIVSYDENGGFFDHVVPPTPPD 366 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGE++TVPDID V GSGGIRGPIGLG+RVP LVISP+SRG L+ HD FDHTS L+LI Sbjct 367 GTPGEYLTVPDIDKVRGSGGIRGPIGLGYRVPGLVISPFSRGGLVAHDVFDHTSQLRLIE 426 Query 421 ARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQC-VPNAVLG 479 RFGVPVPNLTAWR + GDMTS FNF PPNPS+PNL+ + LP+L QC + + Sbjct 427 TRFGVPVPNLTAWRRSVTGDMTSAFNFGVPPNPSRPNLNQSK-RVLPQLAQCGLGVEAVA 485 Query 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 + + PYRVP+PQ+MP QET P RGIPSGLC Sbjct 486 GIFELNPPYRVPYPQAMPAQETTPARGIPSGLC 518 >gi|15609486|ref|NP_216865.1| phospholipase C 3 PLCC [Mycobacterium tuberculosis H37Rv] gi|15841856|ref|NP_336893.1| phospholipase C [Mycobacterium tuberculosis CDC1551] gi|148662177|ref|YP_001283700.1| phospholipase C 3 PlcC [Mycobacterium tuberculosis H37Ra] 31 more sequence titles Length=508 Score = 692 bits (1786), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/513 (68%), Positives = 397/513 (78%), Gaps = 6/513 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 61 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 118 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 119 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 238 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 297 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 298 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 Query 361 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 GTPGE++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 Query 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 479 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG Sbjct 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 Query 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 477 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 >gi|289575041|ref|ZP_06455268.1| phospholipase C 3 plcC [Mycobacterium tuberculosis K85] gi|289539472|gb|EFD44050.1| phospholipase C 3 plcC [Mycobacterium tuberculosis K85] Length=508 Score = 690 bits (1781), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/513 (68%), Positives = 396/513 (78%), Gaps = 6/513 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR + T GP GECVNDPDH Sbjct 61 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINITGGPNGVGECVNDPDHQ 118 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 119 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 238 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 297 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 298 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 Query 361 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 GTPGE++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 358 GTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 Query 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 479 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG Sbjct 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 Query 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 477 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 >gi|294994549|ref|ZP_06800240.1| phospholipase C 3 plcC [Mycobacterium tuberculosis 210] Length=517 Score = 690 bits (1781), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/513 (68%), Positives = 396/513 (78%), Gaps = 6/513 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 10 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 69 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 70 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 127 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 128 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 186 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 187 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 246 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 247 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 306 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 307 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 366 Query 361 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 GTP E++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 367 GTPCEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 426 Query 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 479 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG Sbjct 427 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 485 Query 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 486 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 517 >gi|289758474|ref|ZP_06517852.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] gi|289714038|gb|EFD78050.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] gi|326903965|gb|EGE50898.1| phospholipase C 3 plcC [Mycobacterium tuberculosis W-148] gi|339295251|gb|AEJ47362.1| phospholipase C 3 plcC [Mycobacterium tuberculosis CCDC5079] gi|339298870|gb|AEJ50980.1| phospholipase C 3 plcC [Mycobacterium tuberculosis CCDC5180] Length=508 Score = 689 bits (1778), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/513 (68%), Positives = 396/513 (78%), Gaps = 6/513 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR F AKAA A A A P+IEKAYGAGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 1 MSRRAFLAKAAGAGAAAVLTDWAAPVIEKAYGAGPCSGHLTDIEHIVLCLQENRSFDHYF 60 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS GFD TP +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH Sbjct 61 GTLSAVDGFDTPTP--LFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQ 118 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI H SWNGGAND WLPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF Sbjct 119 WIAAHLSWNGGANDGWLPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFS 177 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY Sbjct 178 SLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYN 237 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+ Sbjct 238 SKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVV 297 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P Sbjct 298 PLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPE 357 Query 361 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 GTP E++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 358 GTPCEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLI 417 Query 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 479 RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG Sbjct 418 GKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLG 476 Query 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 477 FLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 508 >gi|240173290|ref|ZP_04751948.1| phospholipase C 3 plcC [Mycobacterium kansasii ATCC 12478] Length=538 Score = 684 bits (1764), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/513 (69%), Positives = 400/513 (78%), Gaps = 6/513 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F AKA A A A P+IEKAY AGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 31 MSRREFLAKATGAGAAAFLTDWAAPVIEKAYAAGPCSGHLTDIEHIVLCLQENRSFDHYF 90 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS GFD TP +FAQ GWNP TQAVDPAG+TLPYR DTTRGP GECVNDPDH Sbjct 91 GTLSSVDGFDTPTP--LFAQKGWNPQTQAVDPAGITLPYRIDTTRGPNGVGECVNDPDHQ 148 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI H SWNGGAND WL AQ + N PV MG+Y R D+PIHYLLADTFTVCD Y Sbjct 149 WIAAHLSWNGGANDGWLAAQAR-TRSAANTPVVMGYYARPDIPIHYLLADTFTVCDHYHS 207 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGT PNRLYW+S ++PDG GGP ++EP+IQP +SWRIMP+NL DAG+SWKVY Sbjct 208 SLLGGTMPNRLYWISGTVNPDGDQGGPQIVEPSIQPKLTFSWRIMPQNLSDAGISWKVYN 267 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +KLLG LN+T + NG V FK A DPRS+LAR+GI+PTYP+DF DV NNRLP+VSWV+ Sbjct 268 SKLLGGLNDTSLSRNGYVGSFKAAGDPRSDLARYGIAPTYPMDFVLDVINNRLPQVSWVV 327 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P + SEHP+FP+ VGAV IV+ +R LL NPAVWEKTALI+ YDE+GGFFDHV PPT PP Sbjct 328 PLTVDSEHPSFPIAVGAVTIVNLIRTLLRNPAVWEKTALIIAYDEHGGFFDHVTPPTAPP 387 Query 361 GTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 GTPGE++ DI+ V GSGGIRGPIGLG+RVPC VISPYSRG LMVHD FDHTS L+LI Sbjct 388 GTPGEWIPNSVDINKVDGSGGIRGPIGLGYRVPCFVISPYSRGGLMVHDQFDHTSQLQLI 447 Query 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 479 RFGVPVPNLT WR + GDMTS FNFAAPP+PS+PNLDHP LPK+ CVPN VLG Sbjct 448 GKRFGVPVPNLTPWRASLTGDMTSAFNFAAPPDPSRPNLDHP-ARQLPKVANCVPNVVLG 506 Query 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 + + +PYRVP+PQ+MP QE+ P RGIPSG+C Sbjct 507 FLNE-GLPYRVPYPQTMPVQESGPVRGIPSGIC 538 >gi|183983636|ref|YP_001851927.1| membrane-associated phospholipase C 2 PlcB_5 [Mycobacterium marinum M] gi|183176962|gb|ACC42072.1| membrane-associated phospholipase C 2 PlcB_5 [Mycobacterium marinum M] Length=516 Score = 678 bits (1750), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/514 (67%), Positives = 396/514 (78%), Gaps = 8/514 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 M+RR+F AKA G A P+IEKAY AGPC GHLTDIEHIVL +QENRSFDHYF Sbjct 9 MSRREFMAKATGVGAGGFLTDWAAPVIEKAYAAGPCSGHLTDIEHIVLCLQENRSFDHYF 68 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 G+LS GFD TP +F Q GW+P TQ+VDPAG T+PYR DTTRGP GECVNDPDH Sbjct 69 GSLSSVDGFD--TPTSLFQQKGWDPRTQSVDPAGTTVPYRIDTTRGPNGVGECVNDPDHQ 126 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 WI H SWNGG ND WL AQ + Q N PV MG+Y R D+PIHYLLADTFT+CD Y Sbjct 127 WIAAHLSWNGGGNDGWLAAQA-RTRSQANTPVVMGYYARPDIPIHYLLADTFTICDQYHS 185 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 SLLGGT PNRLYW+S ++PDG GGP ++EP IQP +SWR+MPENL DAGVSWKVY Sbjct 186 SLLGGTMPNRLYWISGTVNPDGDKGGPQIVEPTIQPKLTFSWRLMPENLSDAGVSWKVYN 245 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 +KLLG LN+T + NG V FKQA DPRS+LAR+GI+P YP DF D+ NNRLP+VSWV+ Sbjct 246 SKLLGGLNDTSLSRNGYVGSFKQAGDPRSDLARYGIAPRYPADFVLDIMNNRLPQVSWVV 305 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P + SEHP+FPV VGAV IV+ +R LL NPAVWEKTALI+ YDE+GGFFDHV PPTPP Sbjct 306 PLTVESEHPSFPVAVGAVTIVNLIRALLRNPAVWEKTALIIAYDEHGGFFDHVTPPTPPE 365 Query 361 GTPGEFV--TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKL 418 GTPGE++ TV DI++V GSGGIRGPIGLG+RVPC VISPYSRG L+ H+ FDHTS L+L Sbjct 366 GTPGEWIPPTV-DINTVDGSGGIRGPIGLGYRVPCFVISPYSRGGLLAHERFDHTSQLQL 424 Query 419 IRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVL 478 I RFGVPVPNLT WR + GDMTS FNFA PPNPS PNLDHP LPKL CVPNAVL Sbjct 425 IGKRFGVPVPNLTPWRASVTGDMTSAFNFAVPPNPSPPNLDHP-AKQLPKLINCVPNAVL 483 Query 479 GTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 G + + +PYRVP+PQ+ PTQE+ P RG+PSG+C Sbjct 484 GFLNE-GLPYRVPYPQTTPTQESGPVRGVPSGIC 516 >gi|340626764|ref|YP_004745216.1| phospholipase c 4 [Mycobacterium canettii CIPT 140010059] gi|340004954|emb|CCC44102.1| phospholipase c 4 [Mycobacterium canettii CIPT 140010059] Length=530 Score = 631 bits (1628), Expect = 8e-179, Method: Compositional matrix adjust. Identities = 309/436 (71%), Positives = 351/436 (81%), Gaps = 5/436 (1%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPGHLTDIEHIVLLMQENRSFDHYF 60 ++RR+F AK AA A MS AGP+IEKAYGAGPC GHLTDIEH V MQENRSFDHYF Sbjct 9 VSRREFLAKVAAGGAG-ALMSFAGPVIEKAYGAGPCSGHLTDIEHFVFFMQENRSFDHYF 67 Query 61 GTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHS 120 GTLS T GF+ +P +F Q GWNPMTQA+D GVT+PYRFDTTRGP + G CVNDPDHS Sbjct 68 GTLSGTDGFNTVSP--LFQQKGWNPMTQALDATGVTMPYRFDTTRGPFLDGACVNDPDHS 125 Query 121 WIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFC 180 W+ MH SWNGG NDNWLPAQ + + P MG+YTR+D+PIHYLLAD FTVCD YFC Sbjct 126 WVAMHESWNGGVNDNWLPAQAK-TRSAAHTPTVMGYYTRQDIPIHYLLADAFTVCDRYFC 184 Query 181 SLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQ 240 S+LG T PNRLYW+SA IDPDG +GGP L P QP++ + WRIMP+NL DAGVSWKVY+ Sbjct 185 SVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQNLSDAGVSWKVYR 244 Query 241 NKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVL 300 NK LG ++ +V+ Y LV FKQ+ADPRS+L RFG++P+YP FAADV NRLP+VSWV+ Sbjct 245 NKTLGPIS-SVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLANRLPRVSWVI 303 Query 301 PGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPP 360 P L SEHPA P GA AIV+ LRILL+NPAVWEKTALIV+YDENGGFFDHVVP T P Sbjct 304 PNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFFDHVVPATAPA 363 Query 361 GTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIR 420 GTPGE+VTVPDID VPGSGGIRGPIGLGFRVPC VISPYSRGP MVHDTFDHTS L+L+ Sbjct 364 GTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTFDHTSQLRLLE 423 Query 421 ARFGVPVPNLTAWRDA 436 RFGVPVPNLTAWR + Sbjct 424 TRFGVPVPNLTAWRRS 439 >gi|289750954|ref|ZP_06510332.1| phospholipase C 3 plcC [Mycobacterium tuberculosis T92] gi|289691541|gb|EFD58970.1| phospholipase C 3 plcC [Mycobacterium tuberculosis T92] Length=434 Score = 602 bits (1553), Expect = 4e-170, Method: Compositional matrix adjust. Identities = 295/437 (68%), Positives = 342/437 (79%), Gaps = 4/437 (0%) Query 77 VFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDHSWIGMHNSWNGGANDNW 136 +F Q GWNP TQA+DP G+TLPYR +TT GP GECVNDPDH WI H SWNGGAND W Sbjct 1 MFQQKGWNPETQALDPTGITLPYRINTTGGPNGVGECVNDPDHQWIAAHLSWNGGANDGW 60 Query 137 LPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYFCSLLGGTTPNRLYWMSA 196 LPAQ + N PV MG+Y R D+PIHYLLADTFT+CD YF SLLGGT PNRLYW+SA Sbjct 61 LPAQARTRSV-ANTPVVMGYYARPDIPIHYLLADTFTICDQYFSSLLGGTMPNRLYWISA 119 Query 197 WIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVYQNKLLGALNNTVVGYNG 256 ++PDG GGP ++EP IQP ++WRIMP+NL DAG+SWKVY +KLLG LN+T + NG Sbjct 120 TVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAGISWKVYNSKLLGGLNDTSLSRNG 179 Query 257 LVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVG 316 V FKQAADPRS+LAR+GI+P YP DF DV NN LP+VSWV+P + SEHP+FPV VG Sbjct 180 YVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTLPQVSWVVPLTVESEHPSFPVAVG 239 Query 317 AVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFV-TVPDIDSV 375 AV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV P T P GTPGE++ DID V Sbjct 240 AVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHVTPLTAPEGTPGEWIPNSVDIDKV 299 Query 376 PGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRD 435 GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDHTS L+LI RFGVPVPNLT WR Sbjct 300 DGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDHTSQLQLIGKRFGVPVPNLTPWRA 359 Query 436 ATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKTAIPYRVPFPQS 495 + GDMTS FNFAAPP+PS PNLDHP + LPK+ +CVPN VLG + + +PYRVP+PQ+ Sbjct 360 SVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKCVPNVVLGFLNE-GLPYRVPYPQT 417 Query 496 MPTQETAPTRGIPSGLC 512 P QE+ P R IPSG+C Sbjct 418 TPVQESGPARPIPSGIC 434 >gi|333918704|ref|YP_004492285.1| phospholipase C [Amycolicicoccus subflavus DQS3-9A1] gi|333480925|gb|AEF39485.1| Phospholipase C [Amycolicicoccus subflavus DQS3-9A1] Length=529 Score = 530 bits (1365), Expect = 2e-148, Method: Compositional matrix adjust. Identities = 294/511 (58%), Positives = 349/511 (69%), Gaps = 11/511 (2%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPC-PGHLTDIEHIVLLMQENRSFDHY 59 M+RR+FFAKA AA S AGP+IE+AY A P G L DIEH VLLM ENRSFDHY Sbjct 29 MSRREFFAKAFAAGGTVLLTSWAGPVIERAYAADPMGHGTLDDIEHFVLLMLENRSFDHY 88 Query 60 FGTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDH 119 FGT S RGFDD P + Q G+ P P G P+R DTTRG + GEC+NDP H Sbjct 89 FGTQSGVRGFDD--PSAAWNQYGYAPGIGPT-PTGFLNPFRLDTTRGATLNGECINDPTH 145 Query 120 SWIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGYF 179 SW H++WNGG D W+ + GN P TMG+YTR DLP+HY L D FT+CD YF Sbjct 146 SWGPQHHAWNGGRMDQWVTVHLQHEG-PGNGPATMGYYTRDDLPVHYQLTDAFTLCDHYF 204 Query 180 CSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKVY 239 CS++G T PNRLYW+SA IDP GT GGP++ P + P YSWR PENLE+AGVSWKVY Sbjct 205 CSVMGPTDPNRLYWISASIDPAGTHGGPLVYTPELLPQHVYSWRTFPENLEEAGVSWKVY 264 Query 240 QNKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSWV 299 QNK G L++ ++ +G++ F Q+ADP+S L R G++PTYPL+F DV+N LP+VSW+ Sbjct 265 QNKDFGPLSSVLL--DGMLGCFVQSADPQSALYRKGVAPTYPLEFQNDVQNGTLPQVSWI 322 Query 300 LPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPP 359 +P L EHPA P GAV +V L IL SN A+WEKTALIV+YDENGGFFDHV PPT P Sbjct 323 VPSLLECEHPALPPAFGAVGLVQVLDILTSNRALWEKTALIVSYDENGGFFDHVAPPTAP 382 Query 360 PGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLI 419 PGTPGE++T P + SV S GI GPIGLGFRVP +V+SPYSRG L+ D DHTS L+LI Sbjct 383 PGTPGEYLTAP-LASVTESDGIAGPIGLGFRVPSMVVSPYSRGGLVFSDVLDHTSQLRLI 441 Query 420 RARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLG 479 RFGVPVPNLT WR + VGDM++ FNFAA P+P NL P A L QC P+ V G Sbjct 442 EKRFGVPVPNLTPWRRSVVGDMSAAFNFAAAPDPGSVNLGTPWPKAGAALAQCGPDIVTG 501 Query 480 TVTKTAIPYRVPFPQSMPTQETAPTRGIPSG 510 + PY VP P SMP QE TRG PSG Sbjct 502 FFNQ-GTPYAVP-PNSMPRQEPG-TRGRPSG 529 >gi|308401612|ref|ZP_07669413.1| phosphoesterase family protein [Mycobacterium tuberculosis SUMu012] gi|308366040|gb|EFP54891.1| phosphoesterase family protein [Mycobacterium tuberculosis SUMu012] Length=414 Score = 525 bits (1353), Expect = 7e-147, Method: Compositional matrix adjust. Identities = 261/357 (74%), Positives = 295/357 (83%), Gaps = 2/357 (0%) Query 156 FYTRRDLPIHYLLADTFTVCDGYFCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQ 215 +YTR+D+PIHYLLAD FTVCD YFCS+LG T PNRLYW+SA IDPDG +GGP L P Q Sbjct 60 YYTRQDIPIHYLLADAFTVCDRYFCSVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQ 119 Query 216 PLQHYSWRIMPENLEDAGVSWKVYQNKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFG 275 P++ + WRIMP+NL DAGVSWKVY+NK LG ++ +V+ Y LV FKQ+ADPRS+L RFG Sbjct 120 PVRRFGWRIMPQNLSDAGVSWKVYRNKTLGPIS-SVLTYGSLVTSFKQSADPRSDLVRFG 178 Query 276 ISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWE 335 ++P+YP FAADV NRLP+VSWV+P L SEHPA P GA AIV+ LRILL+NPAVWE Sbjct 179 VAPSYPASFAADVLANRLPRVSWVIPNVLESEHPAVPAAAGAFAIVNILRILLANPAVWE 238 Query 336 KTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLV 395 KTALIV+YDENGGFFDHVVP T P GTPGE+VTVPDID VPGSGGIRGPIGLGFRVPC V Sbjct 239 KTALIVSYDENGGFFDHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFV 298 Query 396 ISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSK 455 ISPYSRGP MVHDTFDHTS L+L+ RFGVPVPNLTAWR + GDMTSTFNFA PPN S Sbjct 299 ISPYSRGPQMVHDTFDHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSW 358 Query 456 PNLDHPRLNALPKLPQCVPNAVLGTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 PNLD+P L+AL +PQCVPNA LGT+ + IPYRVP PQ MPTQET PTRGIPSG C Sbjct 359 PNLDYPGLHALSTVPQCVPNAALGTINR-GIPYRVPDPQIMPTQETTPTRGIPSGPC 414 >gi|226361617|ref|YP_002779395.1| phospholipase C [Rhodococcus opacus B4] gi|226240102|dbj|BAH50450.1| phospholipase C [Rhodococcus opacus B4] Length=511 Score = 521 bits (1342), Expect = 1e-145, Method: Compositional matrix adjust. Identities = 293/513 (58%), Positives = 351/513 (69%), Gaps = 12/513 (2%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGP-CPGHLTDIEHIVLLMQENRSFDHY 59 ++RR+F A AAAA A S AGP+I++AY P G L DIEH V LMQENRSFDHY Sbjct 7 ISRRKFLASAAAAGGAAFLSSWAGPVIDRAYAQDPGGSGSLNDIEHFVYLMQENRSFDHY 66 Query 60 FGTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDH 119 +GTLS RGFDD +P + Q GW P P G P+R DTT+G + GEC+NDP H Sbjct 67 YGTLSGVRGFDDPSP--AWQQYGWTPGAGPT-PTGFLEPFRLDTTQGTHLDGECINDPTH 123 Query 120 SWIGMHNSWNGGANDNWLPAQVPFS-PLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGY 178 SW H++WNGGA D W+P + PL G P TMG+YTR D+P+HY LAD FT+CD Y Sbjct 124 SWGPQHDAWNGGAMDRWMPVHIAHEGPLNG--PATMGYYTRADIPVHYDLADAFTICDHY 181 Query 179 FCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKV 238 FCS+LG T PNRLYWM+ IDPDG GGP++ P + P YSWR PENL++AGV WKV Sbjct 182 FCSVLGPTDPNRLYWMTGTIDPDGLAGGPLVETPTVIPRFAYSWRTYPENLQEAGVGWKV 241 Query 239 YQNKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSW 298 Y NK LG +++ V +G++ FKQ +DP S LAR G+ PTYP DF ADV N LP VSW Sbjct 242 YANKDLGPVSS--VALDGMLGCFKQYSDPNSELARRGLDPTYPNDFRADVANGTLPAVSW 299 Query 299 VLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTP 358 ++P EHPA P GAV IV+ L IL SNPA+WEKTALI++YDENGGFFDHV PPTP Sbjct 300 IVPNIFTCEHPALPPAAGAVGIVEVLDILTSNPAIWEKTALIISYDENGGFFDHVTPPTP 359 Query 359 PPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKL 418 PPGTPGE++TVP +++V S GPIGLGFRVP L+ISPYSRG L+ DTFDHTS L+L Sbjct 360 PPGTPGEYLTVP-LNTVAESENNPGPIGLGFRVPSLIISPYSRGGLVASDTFDHTSQLRL 418 Query 419 IRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVL 478 + RFGVPVPNLT WR VGDMTS F+F++ PN P + P + QC PN Sbjct 419 LEQRFGVPVPNLTEWRRGAVGDMTSAFDFSSAPNAGVPAMTDPGPRLQAAIAQCGPNVAA 478 Query 479 GTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGL 511 GT+ A PY VP P SMP QE +P R PSGL Sbjct 479 GTLNAGA-PYPVP-PNSMPVQEPSPLRRRPSGL 509 >gi|111019467|ref|YP_702439.1| phospholipase C [Rhodococcus jostii RHA1] gi|110818997|gb|ABG94281.1| phospholipase C [Rhodococcus jostii RHA1] Length=511 Score = 521 bits (1342), Expect = 1e-145, Method: Compositional matrix adjust. Identities = 293/513 (58%), Positives = 351/513 (69%), Gaps = 12/513 (2%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGP-CPGHLTDIEHIVLLMQENRSFDHY 59 ++RR+F A AAAA A S AGP+I++AY P G L DIEH V LMQENRSFDHY Sbjct 7 ISRRKFLASAAAAGGAAFLSSWAGPVIDRAYAQDPGGSGSLNDIEHFVYLMQENRSFDHY 66 Query 60 FGTLSDTRGFDDTTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGECVNDPDH 119 +GTLS RGFDD +P + Q GW P P G P+R DTT+G + GEC+NDP H Sbjct 67 YGTLSGVRGFDDPSP--AWQQYGWTPGAGPT-PTGFLNPFRLDTTQGAHLDGECINDPTH 123 Query 120 SWIGMHNSWNGGANDNWLPAQVPFS-PLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDGY 178 SW H++WNGGA D W+P + PL G P TMG+YTR D+P+HY LAD FT+CD Y Sbjct 124 SWGPQHDAWNGGAMDRWMPVHIAHEGPLNG--PATMGYYTRADIPVHYDLADAFTICDHY 181 Query 179 FCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWKV 238 FCS+LG T PNRLYWM+ IDPDG GGP++ P + P YSWR PENL++AGVSWKV Sbjct 182 FCSVLGPTDPNRLYWMTGTIDPDGLAGGPLVETPTVIPKFVYSWRTYPENLQEAGVSWKV 241 Query 239 YQNKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPKVSW 298 Y NK LG +++ V +G++ F Q +DP S LAR G+ PTYP DF ADV N LP VSW Sbjct 242 YANKDLGPVSS--VALDGMLGCFTQYSDPNSELARRGLDPTYPNDFRADVANGTLPAVSW 299 Query 299 VLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVPPTP 358 ++P EHPA P GAV IV+ L IL SNPA+WEKTALI++YDENGGFFDHV PPTP Sbjct 300 IVPNIFTCEHPALPPAAGAVGIVEVLDILTSNPAIWEKTALIISYDENGGFFDHVTPPTP 359 Query 359 PPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKL 418 PPGTPGE++TVP +++V S GPIGLGFRVP L+ISPYSRG L+ DTFDHTS L+L Sbjct 360 PPGTPGEYLTVP-LNTVSESENNPGPIGLGFRVPSLIISPYSRGGLVASDTFDHTSQLRL 418 Query 419 IRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVL 478 + RFGVPVPNLT WR VGDMTS F+F++ PN P + P + QC PN Sbjct 419 LEKRFGVPVPNLTEWRRGAVGDMTSAFDFSSAPNAGVPAMTDPGPRLQAAIAQCGPNVAA 478 Query 479 GTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGL 511 GT+ A PY VP P SMP QE +P R PSGL Sbjct 479 GTLNAGA-PYPVP-PNSMPVQEQSPLRRRPSGL 509 >gi|148661554|ref|YP_001283077.1| putative phospholipase C 4 PlcD [Mycobacterium tuberculosis H37Ra] gi|167968627|ref|ZP_02550904.1| phospholipase C plcD [Mycobacterium tuberculosis H37Ra] gi|148505706|gb|ABQ73515.1| putative phospholipase C 4 PlcD [Mycobacterium tuberculosis H37Ra] Length=343 Score = 500 bits (1288), Expect = 2e-139, Method: Compositional matrix adjust. Identities = 251/345 (73%), Positives = 283/345 (83%), Gaps = 2/345 (0%) Query 168 LADTFTVCDGYFCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPE 227 +AD FTVCD YFCS+LG T PNRLYW+SA IDPDG +GGP L P QP++ + WRIMP+ Sbjct 1 MADAFTVCDRYFCSVLGPTLPNRLYWLSATIDPDGQNGGPELQSPTFQPVRRFGWRIMPQ 60 Query 228 NLEDAGVSWKVYQNKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAAD 287 NL DAGVSWKVY+NK LG ++ +V+ Y LV FKQ+ADPRS+L RFG++P+YP FAAD Sbjct 61 NLSDAGVSWKVYRNKTLGPIS-SVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAAD 119 Query 288 VRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENG 347 V NRLP+VSWV+P L SEHPA P GA AIV+ LRILL+NPAVWEKTALIV+YDENG Sbjct 120 VLANRLPRVSWVIPNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENG 179 Query 348 GFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVH 407 GFFDHVVP T P GTPGE+VTVPDID VPGSGGIRGPIGLGFRVPC VISPYSRGP MVH Sbjct 180 GFFDHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVH 239 Query 408 DTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALP 467 DTFDHTS L+L+ RFGVPVPNLTAWR + GDMTSTFNFA PPN S PNLD+P L+AL Sbjct 240 DTFDHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALS 299 Query 468 KLPQCVPNAVLGTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 +PQCVPNA LGT+ + IPYRVP PQ MPTQET PTRGIPSG C Sbjct 300 TVPQCVPNAALGTINR-GIPYRVPDPQIMPTQETTPTRGIPSGPC 343 >gi|298525835|ref|ZP_07013244.1| predicted protein [Mycobacterium tuberculosis 94_M4241A] gi|298495629|gb|EFI30923.1| predicted protein [Mycobacterium tuberculosis 94_M4241A] Length=253 Score = 495 bits (1274), Expect = 8e-138, Method: Compositional matrix adjust. Identities = 247/247 (100%), Positives = 247/247 (100%), Gaps = 0/247 (0%) Query 266 DPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALR 325 DPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALR Sbjct 7 DPRSNLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALR 66 Query 326 ILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPI 385 ILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPI Sbjct 67 ILLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPI 126 Query 386 GLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTF 445 GLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTF Sbjct 127 GLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTF 186 Query 446 NFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKTAIPYRVPFPQSMPTQETAPTR 505 NFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKTAIPYRVPFPQSMPTQETAPTR Sbjct 187 NFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKTAIPYRVPFPQSMPTQETAPTR 246 Query 506 GIPSGLC 512 GIPSGLC Sbjct 247 GIPSGLC 253 >gi|217069518|gb|ACJ83246.1| Rv2349c antigen [Mycobacterium tuberculosis] Length=338 Score = 468 bits (1205), Expect = 8e-130, Method: Compositional matrix adjust. Identities = 230/340 (68%), Positives = 270/340 (80%), Gaps = 3/340 (0%) Query 174 VCDGYFCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAG 233 +CD YF SLLGGT PNRLYW+SA ++PDG GGP ++EP IQP ++WRIMP+NL DAG Sbjct 1 ICDQYFSSLLGGTMPNRLYWISATVNPDGDQGGPQIVEPAIQPKLTFTWRIMPQNLSDAG 60 Query 234 VSWKVYQNKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRNNRL 293 +SWKVY +KLLG LN+T + NG V FKQAADPRS+LAR+GI+P YP DF DV NN L Sbjct 61 ISWKVYNSKLLGGLNDTSLSRNGYVGSFKQAADPRSDLARYGIAPAYPWDFIRDVINNTL 120 Query 294 PKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHV 353 P+VSWV+P + SEHP+FPV VGAV IV+ +R+LL NPAVWEKTALI+ YDE+GGFFDHV Sbjct 121 PQVSWVVPLTVESEHPSFPVAVGAVTIVNLIRVLLRNPAVWEKTALIIAYDEHGGFFDHV 180 Query 354 VPPTPPPGTPGEFV-TVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDH 412 P T P GTPGE++ DID V GSGGIRGPIGLGFRVPC VISPYSRG LMVHD FDH Sbjct 181 TPLTAPEGTPGEWIPNSVDIDKVDGSGGIRGPIGLGFRVPCFVISPYSRGGLMVHDRFDH 240 Query 413 TSTLKLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLPQC 472 TS L+LI RFGVPVPNLT WR + GDMTS FNFAAPP+PS PNLDHP + LPK+ +C Sbjct 241 TSQLQLIGKRFGVPVPNLTPWRASVTGDMTSAFNFAAPPDPSPPNLDHP-VRQLPKVAKC 299 Query 473 VPNAVLGTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 VPN VLG + + +PYRVP+PQ+ P QE+ P R IPSG+C Sbjct 300 VPNVVLGFLNE-GLPYRVPYPQTTPVQESGPARPIPSGIC 338 >gi|15608893|ref|NP_216271.1| phospholipase C 4 PLCD [Mycobacterium tuberculosis H37Rv] gi|3242246|emb|CAB09340.1| PROBABLE PHOSPHOLIPASE C 4 (FRAGMENT) PLCD [Mycobacterium tuberculosis H37Rv] Length=280 Score = 410 bits (1054), Expect = 2e-112, Method: Compositional matrix adjust. Identities = 210/282 (75%), Positives = 234/282 (83%), Gaps = 2/282 (0%) Query 231 DAGVSWKVYQNKLLGALNNTVVGYNGLVNDFKQAADPRSNLARFGISPTYPLDFAADVRN 290 DAGVSWKVY+NK LG ++ +V+ Y LV FKQ+ADPRS+L RFG++P+YP FAADV Sbjct 1 DAGVSWKVYRNKTLGPIS-SVLTYGSLVTSFKQSADPRSDLVRFGVAPSYPASFAADVLA 59 Query 291 NRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFF 350 NRLP+VSWV+P L SEHPA P GA AIV+ LRILL+NPAVWEKTALIV+YDENGGFF Sbjct 60 NRLPRVSWVIPNVLESEHPAVPAAAGAFAIVNILRILLANPAVWEKTALIVSYDENGGFF 119 Query 351 DHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTF 410 DHVVP T P GTPGE+VTVPDID VPGSGGIRGPIGLGFRVPC VISPYSRGP MVHDTF Sbjct 120 DHVVPATAPAGTPGEYVTVPDIDQVPGSGGIRGPIGLGFRVPCFVISPYSRGPQMVHDTF 179 Query 411 DHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPNPSKPNLDHPRLNALPKLP 470 DHTS L+L+ RFGVPVPNLTAWR + GDMTSTFNFA PPN S PNLD+P L+AL +P Sbjct 180 DHTSQLRLLETRFGVPVPNLTAWRRSVTGDMTSTFNFAVPPNSSWPNLDYPGLHALSTVP 239 Query 471 QCVPNAVLGTVTKTAIPYRVPFPQSMPTQETAPTRGIPSGLC 512 QCVPNA LGT+ + IPYRVP PQ MPTQET PTRGIPSG C Sbjct 240 QCVPNAALGTINR-GIPYRVPDPQIMPTQETTPTRGIPSGPC 280 >gi|256389818|ref|YP_003111382.1| phospholipase C [Catenulispora acidiphila DSM 44928] gi|256356044|gb|ACU69541.1| Phospholipase C [Catenulispora acidiphila DSM 44928] Length=542 Score = 384 bits (986), Expect = 2e-104, Method: Compositional matrix adjust. Identities = 223/480 (47%), Positives = 279/480 (59%), Gaps = 32/480 (6%) Query 42 DIEHIVLLMQENRSFDHYFGTLSDTRGFDDTTPPV---------VFAQSGWNPMTQAVDP 92 D+EH+V+LMQENRSFD YFGTLS RGF D P VF Q G+ P A Sbjct 75 DVEHVVVLMQENRSFDQYFGTLSGVRGFSDPAVPTQTVGGTEYTVFNQFGFAPGIGA-SA 133 Query 93 AGVTLPYRFDTTRGPLVAGECVNDPDHSWIGMHNSWNGGANDNWLPAQVPFSPLQGNVPV 152 +G P++ + PL G+ ND HSW H SWN GA D+++ A + + N PV Sbjct 134 SGYLQPFQL-VSNPPLENGQTTNDVSHSWATQHQSWNHGAMDSFITAHLA-ADGAANGPV 191 Query 153 TMGFYTRRDLPIHYLLADTFTVCDGYFCSLLGGTTPNRLYWMSAWIDPDGTDGGPVL--I 210 TMG++TR+DL ++ LAD FT+CDGY CS+LG T PNRL MSA IDP+G GGPV+ Sbjct 192 TMGYFTRQDLAFYHALADAFTICDGYHCSVLGPTDPNRLMLMSASIDPEGAHGGPVVETF 251 Query 211 EPNIQPLQHYSWRIMPENLEDAGVSWKVYQNKLLGALNNTVVGYNGLVNDFKQAADPRS- 269 I SW MPE L AGVSWKVY N +G L + + Y FK +P S Sbjct 252 SNRIGETGKLSWETMPERLLAAGVSWKVY-NDPIGLLALSPLPY------FKNYDNPFSP 304 Query 270 ---NLARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRI 326 L G++P+YP DF +D+ +LP VSW++P EHPA P G + + L Sbjct 305 TGLELIGRGLTPSYPHDFKSDIAAGKLPSVSWIIPPVAQCEHPAAPPYYGEYFVQEVLAA 364 Query 327 LLSNPAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFV-TVPDIDSVPGSGGIRGPI 385 L+SNP VW +T + V YDENGGFFDHV PPT P GT GE++ T+P +GG+ GPI Sbjct 365 LVSNPEVWARTVVFVVYDENGGFFDHVAPPTAPEGTAGEWLATLPS-----AAGGVDGPI 419 Query 386 GLGFRVPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTF 445 GLGFR P LV+SP+S G T DHTS L+ I +RFGV VPNLTAWR GD T Sbjct 420 GLGFRTPALVLSPFSVGGYKYSGTLDHTSVLRFIESRFGVEVPNLTAWRRGVTGDFTGAL 479 Query 446 NFAAPPNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKTAIPYRVPFPQSMPTQETAPTR 505 N AP NP+ P L + Q V NA+ GT+ IPY +P SMP+QE+ P R Sbjct 480 NLTAPANPAFPTLPVVNIGDTSVAEQAVLNALAGTL-DVGIPYPLPTSNSMPSQESTPAR 538 >gi|289762518|ref|ZP_06521896.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] gi|289710024|gb|EFD74040.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] Length=245 Score = 376 bits (965), Expect = 6e-102, Method: Compositional matrix adjust. Identities = 194/244 (80%), Positives = 213/244 (88%), Gaps = 2/244 (0%) Query 271 LARFGISPTYPLDFAADVRNNRLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSN 330 +AR+GI+PTYP DFAADVR NRLPKVSW++P L SEHPA PV +GAV++V ALRILLSN Sbjct 1 MARYGIAPTYPGDFAADVRANRLPKVSWLVPNILQSEHPALPVALGAVSMVTALRILLSN 60 Query 331 PAVWEKTALIVNYDENGGFFDHVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFR 390 PAVWEKTALIV+YDENGGFFDHV PPT PPGTPGEFVTVP+ID+VPGSGGIRGP+GLGFR Sbjct 61 PAVWEKTALIVSYDENGGFFDHVTPPTAPPGTPGEFVTVPNIDAVPGSGGIRGPLGLGFR 120 Query 391 VPCLVISPYSRGPLMVHDTFDHTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAP 450 VPC+VISPYSRGPLMV DTFDHTS LKLIRARFGVPVPN+TAWRD VGDMTS FNFA P Sbjct 121 VPCIVISPYSRGPLMVSDTFDHTSQLKLIRARFGVPVPNMTAWRDGVVGDMTSAFNFATP 180 Query 451 PNPSKPNLDHPRLNALPKLPQCVPNAVLGTVTKT--AIPYRVPFPQSMPTQETAPTRGIP 508 PN ++PNL HP L ALPKLPQC+PN VLGT +IPYRVP+PQ MPTQET P RG P Sbjct 181 PNSTRPNLSHPLLGALPKLPQCIPNVVLGTTDGALPSIPYRVPYPQVMPTQETTPVRGTP 240 Query 509 SGLC 512 SGLC Sbjct 241 SGLC 244 >gi|295837178|ref|ZP_06824111.1| phospholipase C [Streptomyces sp. SPB74] gi|197698526|gb|EDY45459.1| phospholipase C [Streptomyces sp. SPB74] Length=524 Score = 356 bits (914), Expect = 5e-96, Method: Compositional matrix adjust. Identities = 206/498 (42%), Positives = 269/498 (55%), Gaps = 37/498 (7%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGP-CPGHLTDIEHIVLLMQENRSFDHY 59 MTRR+ A A A +SL P + +A AGP G L D+EH+V+LMQENRSFDHY Sbjct 51 MTRRRLLGSAGTVVGATAALSLLPPSVREAVAAGPPHGGSLDDVEHVVMLMQENRSFDHY 110 Query 60 FGTLSDTRGFDDTTPPVVFAQSGWNPMTQ--AVDPAGVTLPYRFDTTRGPLVAGECVNDP 117 FGT+ RGF+D P +G + Q A P G TLP+ DT + + + Sbjct 111 FGTMRGVRGFND--PRAQRLSTGRSVFYQPDAAHPDGYTLPFHLDTH---ATSAQAIPST 165 Query 118 DHSWIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDG 177 H+W H +WN G DNWLPA G P MG+YTR D+P + LA+ FTVCD Sbjct 166 SHAWSVQHEAWNNGRMDNWLPAHRKADGANG--PYVMGYYTREDIPFQFALAEAFTVCDN 223 Query 178 YFCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWK 237 YFCS+ G T PNR+YWM+ +DP+G GGP+L N P Y+W E LE AGVSWK Sbjct 224 YFCSVFGPTWPNRMYWMTGTLDPNGEHGGPIL--DNTAPAGGYTWTTYAERLEAAGVSWK 281 Query 238 VYQNKLLGALNNTVVGYNGLVN--DFKQAADPRSNLARFGISPTYPLDFAADVRNNRLPK 295 VYQ + G N L N +F+ A P L G+ P F AD R +LP Sbjct 282 VYQE-------DDDYGCNMLENFANFRDA-KPGDPLYEKGVRPQPTGTFEADARAGKLPT 333 Query 296 VSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVP 355 VSW++ SEHP + GA + + + SNP +W KTA I+NYDEN G FDHVVP Sbjct 334 VSWIICTSEQSEHPDYLPAAGADYVASKIEAIASNPELWRKTAFILNYDENDGLFDHVVP 393 Query 356 PTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTST 415 PTP PGTP EFV G+ P+G GFRVPC+++SP++ G + FDHTS Sbjct 394 PTPRPGTPDEFVQ-----------GL--PVGGGFRVPCVIVSPWTAGGYAAGEAFDHTSV 440 Query 416 LKLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPN--PSKPNLDHPRLNALPKLPQCV 473 L+ + GV PN++ WR T GD+TS F F +P + P P +L + + Sbjct 441 LQFLERVTGVREPNISQWRRRTFGDLTSAFGFRSPAHRPPHLPEDTAEQLEEARHEVKTL 500 Query 474 PNAVLGTVTKTAIPYRVP 491 P L ++ +P + P Sbjct 501 PKPTLPGTSRQRLPRQEP 518 >gi|302521121|ref|ZP_07273463.1| phospholipase C, phosphocholine-specific [Streptomyces sp. SPB78] gi|302430016|gb|EFL01832.1| phospholipase C, phosphocholine-specific [Streptomyces sp. SPB78] Length=477 Score = 350 bits (899), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 206/502 (42%), Positives = 270/502 (54%), Gaps = 45/502 (8%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPG-HLTDIEHIVLLMQENRSFDHY 59 MTRR+ A A +SL P +++A AGP G L D+EH+V+LMQENRSFDHY Sbjct 4 MTRRRLLGSAGTVAGGAAALSLLPPSVQEAVAAGPRHGGSLDDVEHVVMLMQENRSFDHY 63 Query 60 FGTLSDTRGFDD------TTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGEC 113 FGT+ RGF+D +T VF Q AV+P G TLP+ DT + + Sbjct 64 FGTMRGVRGFNDPRAQRLSTGKSVFFQP------DAVNPDGYTLPFHLDTHS---TSAQA 114 Query 114 VNDPDHSWIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFT 173 + H+W H +WN G DNWLPA G P MG+YTR D+P + LA+ FT Sbjct 115 IPSTSHAWSVQHEAWNNGKMDNWLPAHRKADGKNG--PYVMGYYTREDIPFQFALAEAFT 172 Query 174 VCDGYFCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAG 233 VCD YFCS+ G T PNR+YWM+ +DP+G GGP+L N P Y+W E LE AG Sbjct 173 VCDNYFCSVFGPTWPNRMYWMTGTLDPNGEHGGPILN--NTAPAGGYTWTTYAERLEAAG 230 Query 234 VSWKVYQNKLLGALNNTVVGYNGLVN--DFKQAADPRSNLARFGISPTYPLDFAADVRNN 291 VSW+VYQ + G N L N +F+ A P L G+ P F AD R Sbjct 231 VSWRVYQE-------DDDYGCNMLENFANFRDA-QPGDPLYEKGVRPQPTGTFEADARAG 282 Query 292 RLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFD 351 +LP VSW++ SEHP + GA + + + SNP +W KTA I+NYDEN G FD Sbjct 283 KLPTVSWIICTSEQSEHPDYLPAAGAEYVASKIEAIASNPELWRKTAFILNYDENDGLFD 342 Query 352 HVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFD 411 HVVPPTP GTP EFV G+ P+G GFRVPC+++SP++ G + FD Sbjct 343 HVVPPTPRAGTPDEFVQ-----------GL--PVGGGFRVPCVIVSPWTVGGYAAGEAFD 389 Query 412 HTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPN--PSKPNLDHPRLNALPKL 469 HTS L+ + GV PN++ WR T GD+TS F F +P + P P+ +L Sbjct 390 HTSVLQFLERVTGVREPNISQWRRRTFGDLTSAFGFRSPAHRPPHLPDDTAEQLEEARHE 449 Query 470 PQCVPNAVLGTVTKTAIPYRVP 491 + +P L T +P + P Sbjct 450 VETLPKPTLPGTTAQKLPGQEP 471 >gi|302544869|ref|ZP_07297211.1| phospholipase C [Streptomyces hygroscopicus ATCC 53653] gi|302462487|gb|EFL25580.1| phospholipase C [Streptomyces himastatinicus ATCC 53653] Length=511 Score = 350 bits (898), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 211/485 (44%), Positives = 267/485 (56%), Gaps = 38/485 (7%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGP-CPGHLTDIEHIVLLMQENRSFDHY 59 TRR+ AA + AGA M+L P +++A AGP G L DIEH+VLLMQENRSFDHY Sbjct 40 FTRRRLLGAAAGSLGAGAAMTLLPPSVQQAIAAGPPQGGSLDDIEHVVLLMQENRSFDHY 99 Query 60 FGTLSDTRGFDDTTPPVVFAQSGWNPMTQ--AVDPAGVTLPYRFDTTRGPLVAGECVNDP 117 FGTL RGF D P + +G + Q V+P G LP+R DT + + + Sbjct 100 FGTLKGVRGFAD--PDALTLSTGKSVFHQPDEVNPDGYLLPFRLDTRS---TSAQAIPST 154 Query 118 DHSWIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFTVCDG 177 H+W H +WNGGA D WLPA G P MG++TR D+P + LA+ FTVCD Sbjct 155 SHAWSVQHEAWNGGAMDKWLPAHRKADGENG--PYVMGYHTREDIPFQFALAEAFTVCDN 212 Query 178 YFCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAGVSWK 237 YFCS+ G T PNRLYWM+ IDP G GGPVL +P Y W E L+ AGVSWK Sbjct 213 YFCSVFGPTWPNRLYWMTGTIDPAGVKGGPVLENKAPKP---YRWTTYAERLQKAGVSWK 269 Query 238 VYQNKLLGALNNTVVGYNGLVNDFKQAADPRSN--LARFGISPTYPLDFAADVRNNRLPK 295 VYQ + N L+ +F+Q D R L G+ + F D RN+RLP Sbjct 270 VYQEEDNYGCN--------LLEEFQQFQDARPGDPLYDRGMVHSPAGTFEGDARNDRLPT 321 Query 296 VSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFDHVVP 355 VSW++P +SEHP + GA + + + SNP VW KT I+NYDEN G FDHV P Sbjct 322 VSWIIPTAEVSEHPDYLPAAGADYVASKIEAIASNPDVWRKTVFILNYDENDGLFDHVPP 381 Query 356 PTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFDHTST 415 PTP GT EFV GG+ PIG GFRVPCL++SP++ G FDHTS Sbjct 382 PTPKAGTVDEFV-----------GGL--PIGGGFRVPCLIVSPWTVGGWAAGQAFDHTSV 428 Query 416 LKLIRARFGVPVPNLTAWRDATVGDMTSTFNF--AAPPNPSKPNLDHPRLNALPKLPQCV 473 L+ + GV PN++ WR T GD+TS F F AAP P P+ +L + + + Sbjct 429 LQFLERLTGVKEPNISEWRRRTFGDLTSAFGFGNAAPEPPKLPDDTAEQLEKAKEDVENL 488 Query 474 PNAVL 478 P L Sbjct 489 PKPTL 493 >gi|318058016|ref|ZP_07976739.1| non-hemolytic phospholipase C [Streptomyces sp. SA3_actG] Length=477 Score = 349 bits (895), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 205/502 (41%), Positives = 270/502 (54%), Gaps = 45/502 (8%) Query 1 MTRRQFFAKAAAATTAGAFMSLAGPIIEKAYGAGPCPG-HLTDIEHIVLLMQENRSFDHY 59 MTRR+ A A +SL P +++A AGP G L D+EH+V+LMQENRSFDHY Sbjct 4 MTRRRLLGSAGTVAGGAAALSLLPPSVQEAVAAGPRHGGSLDDVEHVVMLMQENRSFDHY 63 Query 60 FGTLSDTRGFDD------TTPPVVFAQSGWNPMTQAVDPAGVTLPYRFDTTRGPLVAGEC 113 FGT+ RGF+D +T VF Q AV+P G TLP+ DT + + Sbjct 64 FGTMRGVRGFNDPRAQRLSTGKSVFFQP------DAVNPDGYTLPFHLDTHS---TSAQA 114 Query 114 VNDPDHSWIGMHNSWNGGANDNWLPAQVPFSPLQGNVPVTMGFYTRRDLPIHYLLADTFT 173 + H+W H +WN G DNWLPA G P MG+YTR D+P + LA+ FT Sbjct 115 IPSTSHAWSVQHEAWNNGKMDNWLPAHRKADGKNG--PYVMGYYTREDIPFQFALAEAFT 172 Query 174 VCDGYFCSLLGGTTPNRLYWMSAWIDPDGTDGGPVLIEPNIQPLQHYSWRIMPENLEDAG 233 VCD YFCS+ G T PNR+YWM+ +DP+G GGP+L N P Y+W E LE AG Sbjct 173 VCDNYFCSVFGPTWPNRMYWMTGTLDPNGEHGGPILN--NTAPAGGYTWTTYAERLEAAG 230 Query 234 VSWKVYQNKLLGALNNTVVGYNGLVN--DFKQAADPRSNLARFGISPTYPLDFAADVRNN 291 VSW+VYQ + G N L N +F+ A P L G+ P F AD R Sbjct 231 VSWRVYQE-------DDDYGCNMLENFANFRDAK-PGDPLYEKGVRPQPTGTFEADARAG 282 Query 292 RLPKVSWVLPGFLLSEHPAFPVNVGAVAIVDALRILLSNPAVWEKTALIVNYDENGGFFD 351 +LP VSW++ SEHP + GA + + + S+P +W KTA I+NYDEN G FD Sbjct 283 KLPTVSWIICTSEQSEHPDYLPAAGADYVASKIEAIASHPELWRKTAFILNYDENDGLFD 342 Query 352 HVVPPTPPPGTPGEFVTVPDIDSVPGSGGIRGPIGLGFRVPCLVISPYSRGPLMVHDTFD 411 HVVPPTP GTP EFV G+ P+G GFRVPC+++SP++ G + FD Sbjct 343 HVVPPTPRAGTPDEFVQ-----------GL--PVGGGFRVPCVIVSPWTVGGYAAGEAFD 389 Query 412 HTSTLKLIRARFGVPVPNLTAWRDATVGDMTSTFNFAAPPN--PSKPNLDHPRLNALPKL 469 HTS L+ + GV PN++ WR T GD+TS F F +P + P P+ +L Sbjct 390 HTSVLQFLERVTGVREPNISQWRRRTFGDLTSAFGFRSPAHRPPHLPDDTAEQLEEARHE 449 Query 470 PQCVPNAVLGTVTKTAIPYRVP 491 + +P L T +P + P Sbjct 450 VETLPKPTLPGTTAQKLPRQEP 471 Lambda K H 0.320 0.139 0.452 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1113865195328 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40