BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2383c Length=1414 Score E Sequences producing significant alignments: (Bits) Value gi|254551430|ref|ZP_05141877.1| phenyloxazoline synthase mbtB [M... 2801 0.0 gi|289762549|ref|ZP_06521927.1| phenyloxazoline synthase mbtB [M... 2801 0.0 gi|289746161|ref|ZP_06505539.1| phenyloxazoline synthase mbtB [M... 2801 0.0 gi|308376994|ref|ZP_07440798.2| phenyloxazoline synthase mbtB [M... 2800 0.0 gi|15609520|ref|NP_216899.1| phenyloxazoline synthase MBTB (phen... 2800 0.0 gi|289575076|ref|ZP_06455303.1| phenyloxazoline synthase mbtB [M... 2799 0.0 gi|289443905|ref|ZP_06433649.1| phenyloxazoline synthase mbtB [M... 2799 0.0 gi|31793560|ref|NP_856053.1| phenyloxazoline synthase MBTB (phen... 2799 0.0 gi|15841895|ref|NP_336932.1| dihydroaeruginoic acid synthetase [... 2798 0.0 gi|308375868|ref|ZP_07445369.2| phenyloxazoline synthase mbtB [M... 2797 0.0 gi|121638262|ref|YP_978486.1| phenyloxazoline synthase mbtB [Myc... 2796 0.0 gi|340627394|ref|YP_004745846.1| phenyloxazoline synthase [Mycob... 2792 0.0 gi|167968740|ref|ZP_02551017.1| phenyloxazoline synthase mbtB [M... 2588 0.0 gi|298525864|ref|ZP_07013273.1| phenyloxazoline synthase mbtb [M... 2420 0.0 gi|289553828|ref|ZP_06443038.1| phenyloxazoline synthase mbtB [M... 1653 0.0 gi|254774734|ref|ZP_05216250.1| MbtB protein [Mycobacterium aviu... 1608 0.0 gi|342857513|ref|ZP_08714169.1| MbtB protein [Mycobacterium colo... 1601 0.0 gi|254821623|ref|ZP_05226624.1| MbtB protein [Mycobacterium intr... 1596 0.0 gi|289750983|ref|ZP_06510361.1| phenyloxazoline synthase mbtB [M... 1590 0.0 gi|118464419|ref|YP_881228.1| MbtB protein [Mycobacterium avium ... 1560 0.0 gi|336458162|gb|EGO37145.1| amino acid adenylation enzyme/thioes... 1550 0.0 gi|41408275|ref|NP_961111.1| MbtB [Mycobacterium avium subsp. pa... 1544 0.0 gi|296170578|ref|ZP_06852162.1| mycobactin biosynthesis enzyme M... 1535 0.0 gi|333990169|ref|YP_004522783.1| phenyloxazoline synthase MbtB [... 1379 0.0 gi|118469771|ref|YP_888787.1| non-ribosomal peptide synthetase [... 1352 0.0 gi|126436059|ref|YP_001071750.1| amino acid adenylation domain-c... 1292 0.0 gi|108800436|ref|YP_640633.1| amino acid adenylation [Mycobacter... 1288 0.0 gi|120404807|ref|YP_954636.1| amino acid adenylation domain-cont... 1246 0.0 gi|145223279|ref|YP_001133957.1| amino acid adenylation domain-c... 1216 0.0 gi|315443739|ref|YP_004076618.1| amino acid adenylation enzyme/t... 1214 0.0 gi|54022735|ref|YP_116977.1| putative non-ribosomal peptide synt... 1085 0.0 gi|296394827|ref|YP_003659711.1| amino acid adenylation domain-c... 1040 0.0 gi|226361738|ref|YP_002779516.1| non-ribosomal peptide synthetas... 1039 0.0 gi|183983669|ref|YP_001851960.1| phenyloxazoline synthase MbtB [... 1031 0.0 gi|317506255|ref|ZP_07964074.1| amino acid adenylation domain-co... 1028 0.0 gi|118618904|ref|YP_907236.1| phenyloxazoline synthase MbtB [Myc... 1026 0.0 gi|169629210|ref|YP_001702859.1| putative phenyloxazoline syntha... 1024 0.0 gi|240169921|ref|ZP_04748580.1| phenyloxazoline synthase MbtB [M... 1022 0.0 gi|289758508|ref|ZP_06517886.1| phenyloxazoline synthase mbtB [M... 1001 0.0 gi|302526153|ref|ZP_07278495.1| non-ribosomal peptide synthetase... 997 0.0 gi|262200635|ref|YP_003271843.1| amino acid adenylation domain-c... 970 0.0 gi|326383363|ref|ZP_08205050.1| amino acid adenylation domain-co... 959 0.0 gi|269124629|ref|YP_003297999.1| amino acid adenylation domain-c... 957 0.0 gi|158317684|ref|YP_001510192.1| amino acid adenylation domain-c... 929 0.0 gi|134099239|ref|YP_001104900.1| non-ribosomal peptide synthase ... 904 0.0 gi|312198337|ref|YP_004018398.1| amino acid adenylation domain p... 904 0.0 gi|291007147|ref|ZP_06565120.1| non-ribosomal peptide synthase [... 903 0.0 gi|340795784|ref|YP_004761247.1| nonribosomal peptide synthetase... 879 0.0 gi|111223561|ref|YP_714355.1| putative non-ribosomal peptide syn... 855 0.0 gi|343925522|ref|ZP_08765041.1| putative non-ribosomal peptide s... 843 0.0 >gi|254551430|ref|ZP_05141877.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=1414 Score = 2801 bits (7261), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1412/1414 (99%), Positives = 1413/1414 (99%), Gaps = 0/1414 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALR AAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRRAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR Sbjct 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC Sbjct 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE Sbjct 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY Sbjct 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT Sbjct 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI Sbjct 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI Sbjct 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL Sbjct 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA Sbjct 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR Sbjct 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 Query 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA Sbjct 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 Query 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG Sbjct 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 Query 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD Sbjct 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 Query 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET Sbjct 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 Query 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 >gi|289762549|ref|ZP_06521927.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis GM 1503] gi|289710055|gb|EFD74071.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis GM 1503] Length=1414 Score = 2801 bits (7260), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1412/1414 (99%), Positives = 1413/1414 (99%), Gaps = 0/1414 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR Sbjct 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC Sbjct 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE Sbjct 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY Sbjct 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT Sbjct 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI Sbjct 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI Sbjct 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL Sbjct 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA Sbjct 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VGVHDDFFALGGDSVLATQVVAGIRRWLDSP LMVADMFAARTIAALAQLLTGREANADR Sbjct 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPILMVADMFAARTIAALAQLLTGREANADR 1140 Query 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA Sbjct 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 Query 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG Sbjct 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 Query 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD Sbjct 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 Query 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET Sbjct 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 Query 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 >gi|289746161|ref|ZP_06505539.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis 02_1987] gi|294994511|ref|ZP_06800202.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis 210] gi|289686689|gb|EFD54177.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis 02_1987] gi|326903999|gb|EGE50932.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis W-148] gi|339295282|gb|AEJ47393.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis CCDC5079] gi|339298901|gb|AEJ51011.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis CCDC5180] Length=1414 Score = 2801 bits (7260), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1412/1414 (99%), Positives = 1414/1414 (100%), Gaps = 0/1414 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR Sbjct 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC Sbjct 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 QVRVPVPTLLLAD+LAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE Sbjct 661 QVRVPVPTLLLADLLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY Sbjct 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT Sbjct 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI Sbjct 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI Sbjct 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL Sbjct 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA Sbjct 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR Sbjct 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 Query 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA Sbjct 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 Query 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG Sbjct 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 Query 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD Sbjct 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 Query 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET Sbjct 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 Query 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 >gi|308376994|ref|ZP_07440798.2| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis SUMu008] gi|308377998|ref|ZP_07481192.2| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis SUMu009] gi|308349275|gb|EFP38126.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis SUMu008] gi|308353895|gb|EFP42746.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis SUMu009] gi|328458308|gb|AEB03731.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis KZN 4207] Length=1413 Score = 2800 bits (7259), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1412/1413 (99%), Positives = 1413/1413 (100%), Gaps = 0/1413 (0%) Query 2 VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATL 61 +HATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATL Sbjct 1 MHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATL 60 Query 62 AATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGG 121 AATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGG Sbjct 61 AATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGG 120 Query 122 VAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVAD 181 VAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVAD Sbjct 121 VAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVAD 180 Query 182 LRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRI 241 LRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRI Sbjct 181 LRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRI 240 Query 242 LLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALP 301 LLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALP Sbjct 241 LLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALP 300 Query 302 TRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFL 361 TRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFL Sbjct 301 TRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFL 360 Query 362 LNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPG 421 LNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPG Sbjct 361 LNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPG 420 Query 422 LSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTE 481 LSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTE Sbjct 421 LSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTE 480 Query 482 FDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAA 541 FDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAA Sbjct 481 FDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAA 540 Query 542 LNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRV 601 LNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRV Sbjct 541 LNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRV 600 Query 602 GDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQ 661 GDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQ Sbjct 601 GDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQ 660 Query 662 VRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVET 721 VRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVET Sbjct 661 VRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVET 720 Query 722 FIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYE 781 FIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYE Sbjct 721 FIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYE 780 Query 782 VTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATE 841 VTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATE Sbjct 781 VTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATE 840 Query 842 TAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIA 901 TAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIA Sbjct 841 TAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIA 900 Query 902 RGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIE 961 RGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIE Sbjct 901 RGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIE 960 Query 962 AALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLL 1021 AALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLL Sbjct 961 AALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLL 1020 Query 1022 DRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAV 1081 DRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAV Sbjct 1021 DRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAV 1080 Query 1082 GVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRL 1141 GVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRL Sbjct 1081 GVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRL 1140 Query 1142 ELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAA 1201 ELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAA Sbjct 1141 ELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAA 1200 Query 1202 AYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGH 1261 AYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGH Sbjct 1201 AYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGH 1260 Query 1262 CMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDP 1321 CMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDP Sbjct 1261 CMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDP 1320 Query 1322 VLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETH 1381 VLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETH Sbjct 1321 VLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETH 1380 Query 1382 TSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 TSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 TSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1413 >gi|15609520|ref|NP_216899.1| phenyloxazoline synthase MBTB (phenyloxazoline synthetase) [Mycobacterium tuberculosis H37Rv] gi|148662215|ref|YP_001283738.1| dihydroaeruginoic acid synthetase [Mycobacterium tuberculosis H37Ra] gi|148823585|ref|YP_001288339.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis F11] 35 more sequence titles Length=1414 Score = 2800 bits (7259), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1413/1414 (99%), Positives = 1414/1414 (100%), Gaps = 0/1414 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR Sbjct 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC Sbjct 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE Sbjct 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY Sbjct 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT Sbjct 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI Sbjct 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI Sbjct 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL Sbjct 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA Sbjct 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR Sbjct 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 Query 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA Sbjct 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 Query 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG Sbjct 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 Query 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD Sbjct 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 Query 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET Sbjct 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 Query 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 >gi|289575076|ref|ZP_06455303.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis K85] gi|339632409|ref|YP_004724051.1| phenyloxazoline synthase [Mycobacterium africanum GM041182] gi|289539507|gb|EFD44085.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis K85] gi|339331765|emb|CCC27467.1| phenyloxazoline synthase MBTB (phenyloxazoline synthetase) [Mycobacterium africanum GM041182] Length=1414 Score = 2799 bits (7256), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1412/1414 (99%), Positives = 1413/1414 (99%), Gaps = 0/1414 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR Sbjct 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC Sbjct 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE Sbjct 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY Sbjct 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT Sbjct 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI Sbjct 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI Sbjct 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAALQRLPGVHAAAATV PGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL Sbjct 961 EAALQRLPGVHAAAATVFPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA Sbjct 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR Sbjct 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 Query 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA Sbjct 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 Query 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG Sbjct 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 Query 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD Sbjct 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 Query 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET Sbjct 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 Query 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 >gi|289443905|ref|ZP_06433649.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis T46] gi|289570527|ref|ZP_06450754.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis T17] gi|289416824|gb|EFD14064.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis T46] gi|289544281|gb|EFD47929.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis T17] Length=1414 Score = 2799 bits (7255), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1412/1414 (99%), Positives = 1414/1414 (100%), Gaps = 0/1414 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR Sbjct 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC Sbjct 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAH+AAMNTVE Sbjct 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHNAAMNTVE 720 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY Sbjct 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT Sbjct 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI Sbjct 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI Sbjct 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL Sbjct 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA Sbjct 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR Sbjct 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 Query 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA Sbjct 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 Query 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG Sbjct 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 Query 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD Sbjct 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 Query 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET Sbjct 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 Query 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 >gi|31793560|ref|NP_856053.1| phenyloxazoline synthase MBTB (phenyloxazoline synthetase) [Mycobacterium bovis AF2122/97] gi|81834917|sp|Q7TYQ4.1|MBTB_MYCBO RecName: Full=Phenyloxazoline synthase MbtB; AltName: Full=Mycobactin synthetase protein B gi|31619153|emb|CAD97265.1| PHENYLOXAZOLINE SYNTHASE MBTB (PHENYLOXAZOLINE SYNTHETASE) [Mycobacterium bovis AF2122/97] Length=1414 Score = 2799 bits (7255), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1412/1414 (99%), Positives = 1414/1414 (100%), Gaps = 0/1414 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTY+EYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYQEYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR Sbjct 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC Sbjct 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE Sbjct 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY Sbjct 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT Sbjct 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI Sbjct 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI Sbjct 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL Sbjct 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA Sbjct 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR Sbjct 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 Query 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA Sbjct 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 Query 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG Sbjct 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 Query 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD Sbjct 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 Query 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET Sbjct 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 Query 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 >gi|15841895|ref|NP_336932.1| dihydroaeruginoic acid synthetase [Mycobacterium tuberculosis CDC1551] gi|13882163|gb|AAK46746.1| dihydroaeruginoic acid synthetase [Mycobacterium tuberculosis CDC1551] Length=1414 Score = 2798 bits (7254), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1411/1414 (99%), Positives = 1414/1414 (100%), Gaps = 0/1414 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFP+APMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPVAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALR+AAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRTAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR Sbjct 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC Sbjct 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE Sbjct 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY Sbjct 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT Sbjct 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI Sbjct 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI Sbjct 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL Sbjct 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA Sbjct 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR Sbjct 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 Query 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA Sbjct 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 Query 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG Sbjct 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 Query 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD Sbjct 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 Query 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET Sbjct 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 Query 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 >gi|308375868|ref|ZP_07445369.2| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis SUMu007] gi|308344964|gb|EFP33815.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis SUMu007] Length=1413 Score = 2797 bits (7251), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1411/1413 (99%), Positives = 1412/1413 (99%), Gaps = 0/1413 (0%) Query 2 VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATL 61 +HATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATL Sbjct 1 MHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATL 60 Query 62 AATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGG 121 AATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGG Sbjct 61 AATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGG 120 Query 122 VAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVAD 181 VAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVAD Sbjct 121 VAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVAD 180 Query 182 LRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRI 241 LRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRI Sbjct 181 LRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRI 240 Query 242 LLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALP 301 LLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPV DADRDWWAQRIPQLPDPPALP Sbjct 241 LLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVSDADRDWWAQRIPQLPDPPALP 300 Query 302 TRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFL 361 TRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFL Sbjct 301 TRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFL 360 Query 362 LNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPG 421 LNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPG Sbjct 361 LNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPG 420 Query 422 LSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTE 481 LSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTE Sbjct 421 LSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTE 480 Query 482 FDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAA 541 FDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAA Sbjct 481 FDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAA 540 Query 542 LNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRV 601 LNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRV Sbjct 541 LNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRV 600 Query 602 GDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQ 661 GDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQ Sbjct 601 GDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQ 660 Query 662 VRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVET 721 VRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVET Sbjct 661 VRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVET 720 Query 722 FIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYE 781 FIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYE Sbjct 721 FIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYE 780 Query 782 VTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATE 841 VTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATE Sbjct 781 VTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATE 840 Query 842 TAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIA 901 TAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIA Sbjct 841 TAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIA 900 Query 902 RGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIE 961 RGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIE Sbjct 901 RGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIE 960 Query 962 AALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLL 1021 AALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLL Sbjct 961 AALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLL 1020 Query 1022 DRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAV 1081 DRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAV Sbjct 1021 DRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAV 1080 Query 1082 GVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRL 1141 GVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRL Sbjct 1081 GVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRL 1140 Query 1142 ELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAA 1201 ELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAA Sbjct 1141 ELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAA 1200 Query 1202 AYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGH 1261 AYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGH Sbjct 1201 AYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGH 1260 Query 1262 CMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDP 1321 CMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDP Sbjct 1261 CMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDP 1320 Query 1322 VLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETH 1381 VLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETH Sbjct 1321 VLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETH 1380 Query 1382 TSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 TSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 TSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1413 >gi|121638262|ref|YP_978486.1| phenyloxazoline synthase mbtB [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224990756|ref|YP_002645443.1| phenyloxazoline synthase [Mycobacterium bovis BCG str. Tokyo 172] gi|121493910|emb|CAL72385.1| Phenyloxazoline synthase mbtB [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224773869|dbj|BAH26675.1| phenyloxazoline synthase [Mycobacterium bovis BCG str. Tokyo 172] gi|341602300|emb|CCC64974.1| Phenyloxazoline synthase mbtB [Mycobacterium bovis BCG str. Moreau RDJ] Length=1414 Score = 2796 bits (7248), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1411/1414 (99%), Positives = 1413/1414 (99%), Gaps = 0/1414 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTY+EYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYQEYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR Sbjct 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC Sbjct 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE Sbjct 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY Sbjct 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT Sbjct 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI Sbjct 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI Sbjct 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL Sbjct 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA Sbjct 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR Sbjct 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 Query 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA Sbjct 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 Query 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHL APLTLFG Sbjct 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLPAPLTLFG 1260 Query 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD Sbjct 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 Query 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET Sbjct 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 Query 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 >gi|340627394|ref|YP_004745846.1| phenyloxazoline synthase [Mycobacterium canettii CIPT 140010059] gi|340005584|emb|CCC44746.1| phenyloxazoline synthase MBTB (phenyloxazoline synthetase) [Mycobacterium canettii CIPT 140010059] Length=1414 Score = 2792 bits (7237), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1408/1414 (99%), Positives = 1411/1414 (99%), Gaps = 0/1414 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFP+SVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPLSVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAA RAQAVQEALRSAAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAVRAQAVQEALRSAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR Sbjct 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC Sbjct 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE Sbjct 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIV VDEAQRRDPDAWARLIDTY Sbjct 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVAVDEAQRRDPDAWARLIDTY 780 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 EVTALNFMPGWLDML+EVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT Sbjct 781 EVTALNFMPGWLDMLVEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI Sbjct 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI Sbjct 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL Sbjct 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRAL RIVADILGRANDA Sbjct 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALCRIVADILGRANDA 1080 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR Sbjct 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 Query 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA Sbjct 1141 LELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAA 1200 Query 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG Sbjct 1201 AAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFG 1260 Query 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD Sbjct 1261 HCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTD 1320 Query 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET Sbjct 1321 PVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWET 1380 Query 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1381 HTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 >gi|167968740|ref|ZP_02551017.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis H37Ra] Length=1306 Score = 2588 bits (6709), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1305/1306 (99%), Positives = 1305/1306 (99%), Gaps = 0/1306 (0%) Query 109 MWVGRHDHQQLGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPP 168 MWVGRHDHQQLGGVAGHLYVEFDGA VDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPP Sbjct 1 MWVGRHDHQQLGGVAGHLYVEFDGAGVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPP 60 Query 169 AAGSRDFPISVADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVD 228 AAGSRDFPISVADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVD Sbjct 61 AAGSRDFPISVADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVD 120 Query 229 LDMQAADAMSYRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWA 288 LDMQAADAMSYRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWA Sbjct 121 LDMQAADAMSYRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWA 180 Query 289 QRIPQLPDPPALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFA 348 QRIPQLPDPPALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFA Sbjct 181 QRIPQLPDPPALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFA 240 Query 349 NVLARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQE 408 NVLARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQE Sbjct 241 NVLARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQE 300 Query 409 ALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIIS 468 ALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIIS Sbjct 301 ALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIIS 360 Query 469 QGPQVLLDAQVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSP 528 QGPQVLLDAQVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSP Sbjct 361 QGPQVLLDAQVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSP 420 Query 529 SALPAAQRAVRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQAS 588 SALPAAQRAVRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQAS Sbjct 421 SALPAAQRAVRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQAS 480 Query 589 AVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATG 648 AVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATG Sbjct 481 AVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATG 540 Query 649 SVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGV 708 SVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGV Sbjct 541 SVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGV 600 Query 709 EVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRR 768 EVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRR Sbjct 601 EVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRR 660 Query 769 DPDAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQA 828 DPDAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQA Sbjct 661 DPDAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQA 720 Query 829 PSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDW 888 PSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDW Sbjct 721 PSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDW 780 Query 889 VAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRV 948 VAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRV Sbjct 781 VAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRV 840 Query 949 KISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADL 1008 KISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADL Sbjct 841 KISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADL 900 Query 1009 VPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRR 1068 VPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRR Sbjct 901 VPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRR 960 Query 1069 IVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALA 1128 IVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALA Sbjct 961 IVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALA 1020 Query 1129 QLLTGREANADRLELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPG 1188 QLLTGREANADRLELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPG Sbjct 1021 QLLTGREANADRLELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPG 1080 Query 1189 AVLVFPHAGGAAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAG 1248 AVLVFPHAGGAAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAG Sbjct 1081 AVLVFPHAGGAAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALALELFEAG 1140 Query 1249 DWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRD 1308 DWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRD Sbjct 1141 DWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPLPTADRD 1200 Query 1309 VLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDH 1368 VLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDH Sbjct 1201 VLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDH 1260 Query 1369 RISREMLTSWETHTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 RISREMLTSWETHTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 1261 RISREMLTSWETHTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1306 >gi|298525864|ref|ZP_07013273.1| phenyloxazoline synthase mbtb [Mycobacterium tuberculosis 94_M4241A] gi|298495658|gb|EFI30952.1| phenyloxazoline synthase mbtb [Mycobacterium tuberculosis 94_M4241A] Length=1280 Score = 2420 bits (6271), Expect = 0.0, Method: Compositional matrix adjust. Identities = 1220/1221 (99%), Positives = 1221/1221 (100%), Gaps = 0/1221 (0%) Query 194 LAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAALYDGR 253 LAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAALYDGR Sbjct 60 LAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAALYDGR 119 Query 254 EPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRAGGERDRRRS 313 EPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRAGGERDRRRS Sbjct 120 EPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRAGGERDRRRS 179 Query 314 TRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLNLPLFSRQALH 373 TRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLNLPLFSRQALH Sbjct 180 TRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLNLPLFSRQALH 239 Query 374 PDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRG 433 PDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRG Sbjct 240 PDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRG 299 Query 434 TQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVR 493 TQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVR Sbjct 300 TQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVR 359 Query 494 EGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGRTAAPSTEA 553 EGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGRTAAPSTEA Sbjct 360 EGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGRTAAPSTEA 419 Query 554 LHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRVGDTVAVLGPKTG 613 LHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRVGDTVAVLGPKTG Sbjct 420 LHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRVGDTVAVLGPKTG 479 Query 614 EQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVRVPVPTLLLAD 673 EQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVRVPVPTLLLAD Sbjct 480 EQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVRVPVPTLLLAD 539 Query 674 VLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGAADR 733 +LAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGAADR Sbjct 540 LLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGAADR 599 Query 734 WLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLD 793 WLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLD Sbjct 600 WLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLD 659 Query 794 MLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQD 853 MLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQD Sbjct 660 MLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQD 719 Query 854 AANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAE 913 AANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAE Sbjct 720 AANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAE 779 Query 914 RFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAA 973 RFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAA Sbjct 780 RFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAA 839 Query 974 AATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRIPFTDSGKID 1033 AATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRIPFTDSGKID Sbjct 840 AATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRIPFTDSGKID 899 Query 1034 RAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGD 1093 RAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGD Sbjct 900 RAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGD 959 Query 1094 SVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLEIAN 1153 SVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLEIAN Sbjct 960 SVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLEIAN 1019 Query 1154 MTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAAAYRWLAKSLVAN 1213 MTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAAAYRWLAKSLVAN Sbjct 1020 MTSADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAAAYRWLAKSLVAN 1079 Query 1214 DVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGHCMGAIVAFEFAR 1273 DVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGHCMGAIVAFEFAR Sbjct 1080 DVDTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGHCMGAIVAFEFAR 1139 Query 1274 LAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELL 1333 LAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELL Sbjct 1140 LAERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELL 1199 Query 1334 VPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDG 1393 VPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDG Sbjct 1200 VPAVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDG 1259 Query 1394 GHFYLNDHLDAVARMVSADVR 1414 GHFYLNDHLDAVARMVSADVR Sbjct 1260 GHFYLNDHLDAVARMVSADVR 1280 >gi|289553828|ref|ZP_06443038.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis KZN 605] gi|289438460|gb|EFD20953.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis KZN 605] Length=832 Score = 1653 bits (4281), Expect = 0.0, Method: Compositional matrix adjust. Identities = 831/832 (99%), Positives = 832/832 (100%), Gaps = 0/832 (0%) Query 583 LRDQASAVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAE 642 +RDQASAVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAE Sbjct 1 MRDQASAVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAE 60 Query 643 RILATGSVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGST 702 RILATGSVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGST Sbjct 61 RILATGSVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGST 120 Query 703 GEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVV 762 GEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVV Sbjct 121 GEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVV 180 Query 763 DEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLAR 822 DEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLAR Sbjct 181 DEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLAR 240 Query 823 RLQVQAPSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSG 882 RLQVQAPSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSG Sbjct 241 RLQVQAPSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSG 300 Query 883 DDCPDWVAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVG 942 DDCPDWVAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVG Sbjct 301 DDCPDWVAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVG 360 Query 943 RADHRVKISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIR 1002 RADHRVKISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIR Sbjct 361 RADHRVKISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIR 420 Query 1003 QQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVL 1062 QQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVL Sbjct 421 QQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVL 480 Query 1063 QRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAAR 1122 QRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAAR Sbjct 481 QRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAAR 540 Query 1123 TIAALAQLLTGREANADRLELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFT 1182 TIAALAQLLTGREANADRLELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFT Sbjct 541 TIAALAQLLTGREANADRLELVAEVYLEIANMTSADVMAALDPIEQPAQPAFKPWVKRFT 600 Query 1183 GTDKPGAVLVFPHAGGAAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALAL 1242 GTDKPGAVLVFPHAGGAAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALAL Sbjct 601 GTDKPGAVLVFPHAGGAAAAYRWLAKSLVANDVDTFVVQYPQRADRRSHPAADSIEALAL 660 Query 1243 ELFEAGDWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPL 1302 ELFEAGDWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPL Sbjct 661 ELFEAGDWHLTAPLTLFGHCMGAIVAFEFARLAERNGVPVRALWASSGQAPSTVAASGPL 720 Query 1303 PTADRDVLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAV 1362 PTADRDVLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAV Sbjct 721 PTADRDVLADMVDLGGTDPVLLEDEEFVELLVPAVKADYRALSGYSCPPDVRIRANIHAV 780 Query 1363 GGNRDHRISREMLTSWETHTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 1414 GGNRDHRISREMLTSWETHTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR Sbjct 781 GGNRDHRISREMLTSWETHTSGRFTLSHFDGGHFYLNDHLDAVARMVSADVR 832 >gi|254774734|ref|ZP_05216250.1| MbtB protein [Mycobacterium avium subsp. avium ATCC 25291] Length=1166 Score = 1608 bits (4164), Expect = 0.0, Method: Compositional matrix adjust. Identities = 847/1177 (72%), Positives = 963/1177 (82%), Gaps = 19/1177 (1%) Query 2 VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATL 61 +HA A SE IRAEVAELLGV DA+ PG+NL+GQGLDSIR+M+L GRWRR+GIAVDFATL Sbjct 1 MHAPARSEDIRAEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRQGIAVDFATL 60 Query 62 AATPTIEAWSQLVSAGTGVAPTAVAAPGDAGL---SQEGEPFPLAPMQHAMWVGRHDHQQ 118 A TPT+EAW++LV+AG A S+E EPF LAPMQHAMWVGR ++QQ Sbjct 61 AETPTVEAWAELVNAGRPSADRPAEPADAPADAARSREDEPFSLAPMQHAMWVGRQENQQ 120 Query 119 LGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPIS 178 LGGVAGHLYVEFDG +DP+RLRAAAT LA RHPMLRV+FLPDGTQRI PA FP+ Sbjct 121 LGGVAGHLYVEFDGGGIDPERLRAAATALARRHPMLRVRFLPDGTQRIAPADEFGPFPVH 180 Query 179 VADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMS 238 V DLR + D+RLA IR AKSHQQLDGAVFELA+TLLP ER+RLHVDLDMQAADAMS Sbjct 181 VEDLRERSQGEADRRLAAIRAAKSHQQLDGAVFELAVTLLPAERSRLHVDLDMQAADAMS 240 Query 239 YRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPP 298 YR L+ADLAALY GR+ P L YTYR+YRQAIEAE+ PQP RDADR WWAQR+P+LPDPP Sbjct 241 YRTLMADLAALYLGRDLPELHYTYRQYRQAIEAEDARPQPARDADRAWWAQRLPELPDPP 300 Query 299 ALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASS 358 ALPT AG R +STRRWHWLDP TRDALFARA+ARG TPAM LAA FAN LARWS +S Sbjct 301 ALPTTAG--RAENQSTRRWHWLDPHTRDALFARAQARGFTPAMALAAGFANTLARWSTTS 358 Query 359 RFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSA 418 RFLLN+PLF RQALHPDVD LVGDFTSSLLLDVDLT A TA+ARAQ VQ A+R+AA HSA Sbjct 359 RFLLNVPLFGRQALHPDVDFLVGDFTSSLLLDVDLTRANTASARAQVVQAAMRTAAAHSA 418 Query 419 YPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQ 478 YPGLS+LRDLSRHRGTQVLAPVVFTSALGLG+LF DVT QFGTPGWIISQGPQVLLDAQ Sbjct 419 YPGLSLLRDLSRHRGTQVLAPVVFTSALGLGELFSSDVTGQFGTPGWIISQGPQVLLDAQ 478 Query 479 VTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAV 538 VTEFDGGVLVNWDVREGVF GVIDAMF H +DELLRLA+ D+AW+AP P ALP AQRAV Sbjct 479 VTEFDGGVLVNWDVREGVFPAGVIDAMFAHHIDELLRLASADEAWEAPGPPALPEAQRAV 538 Query 539 RAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAG 598 R A NGRTA PS EALHDGFFRQA+Q+PDAPAVFASSGDLSYAQLRDQA AVAAALRAAG Sbjct 539 REAANGRTAEPSGEALHDGFFRQAEQRPDAPAVFASSGDLSYAQLRDQALAVAAALRAAG 598 Query 599 LRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGP 658 + GDT+AV+GPKT EQ+ A+LGIL+ G VYLPIGVDQPRDRAERIL +G V+LA+VCG Sbjct 599 VTAGDTIAVMGPKTAEQIPALLGILSVGAVYLPIGVDQPRDRAERILESGGVSLAVVCG- 657 Query 659 PCQVRVPVPTLLLADVLAAAPA--EFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAM 716 ++ +PVP ++LAD+L APA E DP ALAYVLFTSGSTGEPKGVEV HDAAM Sbjct 658 GQRLSMPVPEVVLADILGGAPASTEITSARVDPAALAYVLFTSGSTGEPKGVEVTHDAAM 717 Query 717 NTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARL 776 NTVE RHF++G ADR LAL+TLE D+SV+D+F LR+GG+IVVVDEAQRRDPDAWARL Sbjct 718 NTVEFIGRHFDIGPADRCLALSTLEGDISVMDVFVTLRTGGSIVVVDEAQRRDPDAWARL 777 Query 777 IDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGL 836 ID ++VT L+FMPGWL+ML+EVG GRLSS+R V GGDWVRP++ RRL+ +AP+ RFAGL Sbjct 778 IDAHQVTVLHFMPGWLEMLVEVGRGRLSSVRVVPTGGDWVRPEVVRRLRAEAPNLRFAGL 837 Query 837 GGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVS 896 GGATET VH +IFEV + +P DW ++P+GVP PNNACRVV D+G DCPDWV GE WVS Sbjct 838 GGATETPVHNSIFEVTEP--IPDDWTALPFGVPLPNNACRVVDDTGADCPDWVPGEYWVS 895 Query 897 GRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVE 956 GRGIARGYRGRP+LTAERFVEHDGR WYRTGDL RYW DGTLEFVGRADHRVKISGYRVE Sbjct 896 GRGIARGYRGRPDLTAERFVEHDGRIWYRTGDLVRYWPDGTLEFVGRADHRVKISGYRVE 955 Query 957 LGEIEAALQRLPGVHAAAATVL--PGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMI 1014 LGEIE AL+R+PGV A A ++ G SDVLAA VC DDA VTAE IRQ LADLVPAHMI Sbjct 956 LGEIETALRRVPGVRTAVAALIAVSGESDVLAAQVCADDATVTAEGIRQSLADLVPAHMI 1015 Query 1015 PRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADIL 1074 PRH+T+++RI FTD+GK+DR V L V +S + + AP T LQ AL IV D+L Sbjct 1016 PRHITVVERIGFTDAGKLDRRAVARELEGAVSQS--QRPGHRAPSTPLQSALAMIVGDLL 1073 Query 1075 GRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGR 1134 GR N +G+ DDFFALGGDSVLATQ VA IR WLD+P +MVAD+FA RT+++LA +L Sbjct 1074 GRQN--IGIDDDFFALGGDSVLATQAVARIRAWLDAPDIMVADIFANRTVSSLAAVLGAG 1131 Query 1135 EANADRLELVAEVYLEIANMTSADVMAALDPIEQPAQ 1171 E + RL+ VAE+YLE+ M + V+AA +QPA+ Sbjct 1132 ERDPGRLDQVAELYLEVIGMDAESVLAA---SQQPAK 1165 >gi|342857513|ref|ZP_08714169.1| MbtB protein [Mycobacterium colombiense CECT 3035] gi|342134846|gb|EGT88012.1| MbtB protein [Mycobacterium colombiense CECT 3035] Length=1167 Score = 1601 bits (4145), Expect = 0.0, Method: Compositional matrix adjust. Identities = 847/1172 (73%), Positives = 962/1172 (83%), Gaps = 22/1172 (1%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHA+A SE IRAEVAELLGV DA+ PG+NL+GQGLDSIR+M+L GRWRR+GI VDFAT Sbjct 1 MVHASARSEDIRAEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRQGIDVDFAT 60 Query 61 LAATPTIEAWSQLVSAG---TGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQ 117 LA TPT+EAW++LVSAG T AAPG A S EPFPLAPMQHAMWVGR D+Q Sbjct 61 LAETPTVEAWARLVSAGGQATDRQALPAAAPGGAEPSGAYEPFPLAPMQHAMWVGRQDNQ 120 Query 118 QLGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPI 177 QLGGVAGHLYVEFDG +DP+RLRAAAT LA RHPMLRV+FLPDGTQRI PA S +F + Sbjct 121 QLGGVAGHLYVEFDGGPIDPERLRAAATELARRHPMLRVRFLPDGTQRITPADESGEFAV 180 Query 178 SVADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAM 237 SV DLR ++ D V++RLA IRDAKSHQQLDGAVFELA+TLLPG R+RLHVDLDMQAADAM Sbjct 181 SVEDLRSLSADDVERRLAAIRDAKSHQQLDGAVFELAVTLLPGGRSRLHVDLDMQAADAM 240 Query 238 SYRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDP 297 SYR L+ADLAA+Y G++ P L YTYR+YRQA+EAE PQP R+ADR WW QR+P+LPDP Sbjct 241 SYRTLMADLAAVYGGQDLPELNYTYRQYRQAVEAEAAQPQPAREADRAWWEQRLPELPDP 300 Query 298 PALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSAS 357 PALP+ G R STRRWHWLDPQTRDALFARA+ RGITPAM LAA FAN LARWS + Sbjct 301 PALPSI--GARGCNHSTRRWHWLDPQTRDALFARAQRRGITPAMALAAGFANTLARWSTT 358 Query 358 SRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHS 417 SRFLLN+PLF RQ LHPDVD LVGDFTSSLLLD+DL GARTAAARAQ VQ A+R+AA HS Sbjct 359 SRFLLNVPLFGRQPLHPDVDSLVGDFTSSLLLDIDLVGARTAAARAQVVQAAMRTAAAHS 418 Query 418 AYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDA 477 AYPGLSVLRDLSRHRGTQVLAPVVFTSALGLG+LF +VT+QFGTPGWIISQGPQVLLDA Sbjct 419 AYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGELFGRNVTDQFGTPGWIISQGPQVLLDA 478 Query 478 QVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRA 537 QVTEF+GGVLVNWDVREG+F PGVIDAMF + +DELL+LA +D+WDAP P+ALP AQR Sbjct 479 QVTEFNGGVLVNWDVREGMFPPGVIDAMFGYHIDELLQLAYAEDSWDAPGPAALPEAQRG 538 Query 538 VRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAA 597 VR A N RTA PS EALHDGFFRQA++QPDAPAVFASSGDLSYAQLRDQA AVAAALR A Sbjct 539 VREAANARTAEPSGEALHDGFFRQAERQPDAPAVFASSGDLSYAQLRDQALAVAAALRTA 598 Query 598 GLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCG 657 G+ GDTVAV+GPKT EQ+ A+LGIL+ G VYLPIGVDQPRDRAERIL TG+V+LALVCG Sbjct 599 GIAAGDTVAVMGPKTAEQIPALLGILSVGAVYLPIGVDQPRDRAERILDTGAVSLALVCG 658 Query 658 PPCQVRVPVPTLLLADVLAAA--PAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAA 715 + +PVP L+LADVL AE DP+ LAYVLFTSGSTGEPKGVEV HDAA Sbjct 659 GQ-PLSLPVPELVLADVLGNIRPGAEISSARVDPSDLAYVLFTSGSTGEPKGVEVTHDAA 717 Query 716 MNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWAR 775 MNTVE RHFE+G ADR LAL+TLE D+SV+D+F LR+GGAIVVVDEAQRRDPDAWAR Sbjct 718 MNTVEFIGRHFEIGPADRCLALSTLEGDISVMDVFVTLRTGGAIVVVDEAQRRDPDAWAR 777 Query 776 LIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAG 835 LID ++VT L+FMPGWL+ML+EVG GRLSS+R + GGDWVRP++ RRLQ +AP+ RFAG Sbjct 778 LIDAHKVTVLHFMPGWLEMLIEVGRGRLSSVRVIPTGGDWVRPEVVRRLQAEAPNLRFAG 837 Query 836 LGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWV 895 LGGATET VH TIFEV +A +P DW ++P+GVP PNNACRVV D+G DCPDWV GE WV Sbjct 838 LGGATETPVHNTIFEVTEA--IPEDWTALPFGVPLPNNACRVVDDNGADCPDWVPGEYWV 895 Query 896 SGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRV 955 SGRGIARGYRGRP+LTAERFVEH GR WYRTGDL RYW DGTLEFVGRADHRVKISGYRV Sbjct 896 SGRGIARGYRGRPDLTAERFVEHGGRLWYRTGDLVRYWPDGTLEFVGRADHRVKISGYRV 955 Query 956 ELGEIEAALQRLPGVHAAAATVLPGG--SDVLAAAVCVDDAGVTAESIRQQLADLVPAHM 1013 ELGEIE AL+R+PGV A A ++ G SDVLAA VC DD +T E IR+ L DLVPAHM Sbjct 956 ELGEIETALRRVPGVRTAVAALIAGSGESDVLAAQVCTDDMTLTGERIRRCLDDLVPAHM 1015 Query 1014 IPRHVTLLDRIPFTDSGKIDRAEVGALLAAEV---ERSGDRSAPYAAPRTVLQRALRRIV 1070 IPRH+ +++RI FTD+GK+DR V L A V +R G R AP + L+ AL I+ Sbjct 1016 IPRHIAVVERIGFTDAGKLDRRSVARELEAAVSQAQRPGHR-----APSSPLESALAMIL 1070 Query 1071 ADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQL 1130 D+LGR N VGV DDFFALGGDSVLATQ VA IR WLD+P +MVAD+FA RT+AALA + Sbjct 1071 GDLLGRDN--VGVDDDFFALGGDSVLATQAVARIRAWLDAPGIMVADVFANRTVAALAAV 1128 Query 1131 LTGREANADRLELVAEVYLEIANMTSADVMAA 1162 L+ E + DRLE VAE+YLE+ M + V+AA Sbjct 1129 LSAGENDPDRLEQVAELYLEVIGMDAESVLAA 1160 >gi|254821623|ref|ZP_05226624.1| MbtB protein [Mycobacterium intracellulare ATCC 13950] Length=1167 Score = 1596 bits (4132), Expect = 0.0, Method: Compositional matrix adjust. Identities = 853/1178 (73%), Positives = 969/1178 (83%), Gaps = 19/1178 (1%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHA A SE IRAEVAELLGV ADA+ PG+NL+GQGLDSIR+M+L GRWRR+GIAVDFAT Sbjct 1 MVHAPARSEDIRAEVAELLGVDADAVQPGSNLIGQGLDSIRIMTLAGRWRRQGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVA---PTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQ 117 LA TPT+EAW++LV+AG A AP DAG S E EPF LAPMQHAMWVGR ++Q Sbjct 61 LAETPTVEAWAELVNAGKPSADRPAEPADAPADAGRSGEDEPFSLAPMQHAMWVGRQENQ 120 Query 118 QLGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPI 177 QLGGVAGHLYVEFDG +DP+RLRAAAT LA RHPMLRV+FLPDGTQRI PA FP+ Sbjct 121 QLGGVAGHLYVEFDGGGIDPERLRAAATALARRHPMLRVRFLPDGTQRIAPADEFGPFPV 180 Query 178 SVADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAM 237 V DLR + D+RLA IR AKSHQQLDGAVFELA+TLLP ER+RLHVDLDMQAADAM Sbjct 181 HVEDLRERSTGEADRRLAAIRAAKSHQQLDGAVFELAVTLLPAERSRLHVDLDMQAADAM 240 Query 238 SYRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDP 297 SYR L+ADLAALY GR+ P LGYTYR+YR AIEAE+ PQP RDADR WWA+R+P+LPDP Sbjct 241 SYRTLMADLAALYLGRDLPELGYTYRQYRHAIEAEDARPQPARDADRAWWARRLPELPDP 300 Query 298 PALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSAS 357 PALPT G R +STRRWHWLDP TRDALFARA+ARG TPAM LAA FAN LARWS + Sbjct 301 PALPTTGG--RAENQSTRRWHWLDPHTRDALFARAQARGFTPAMALAAGFANTLARWSTT 358 Query 358 SRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHS 417 SRFLLN+PLF RQALHPDVD LVGDFTSSLLLDVDLT A TAAARAQ VQ+A+R+AA HS Sbjct 359 SRFLLNVPLFGRQALHPDVDSLVGDFTSSLLLDVDLTRANTAAARAQVVQDAMRTAAAHS 418 Query 418 AYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDA 477 AYPGL+VLRDLSRHRGTQVLAPVVFTSALGLG+LF DVT QFGTPGWIISQGPQVLLDA Sbjct 419 AYPGLAVLRDLSRHRGTQVLAPVVFTSALGLGELFSSDVTGQFGTPGWIISQGPQVLLDA 478 Query 478 QVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRA 537 QVTEFDGGVLVNWDVREGVF GVIDAMF H +DELLRLA+ D+AW+AP P ALP AQRA Sbjct 479 QVTEFDGGVLVNWDVREGVFPAGVIDAMFAHHIDELLRLASADEAWEAPGPPALPEAQRA 538 Query 538 VRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAA 597 VR A NGRTA PS EALHDGFFRQA+Q+PDAPAVFASSGDLSYAQLRDQA AVAAALRAA Sbjct 539 VREAANGRTAEPSGEALHDGFFRQAEQRPDAPAVFASSGDLSYAQLRDQALAVAAALRAA 598 Query 598 GLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCG 657 G+ GDT+AV+GPKT EQ+ A+LGIL+ G VYLPIGVDQPRDRAERIL +G V+LA+VCG Sbjct 599 GVTAGDTIAVMGPKTAEQIPALLGILSVGAVYLPIGVDQPRDRAERILESGGVSLAVVCG 658 Query 658 PPCQVRVPVPTLLLADVLAAAPA--EFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAA 715 ++ +PVP ++LAD+L APA E DP ALAYVLFTSGSTGEPKGVEV HDAA Sbjct 659 -GQRLSMPVPEVVLADILGGAPASTEITSARVDPAALAYVLFTSGSTGEPKGVEVTHDAA 717 Query 716 MNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWAR 775 MNTVE RHF++G ADR LAL+TLE D+SV+D+F LR+GG+IVVVDE QRRDPDAWAR Sbjct 718 MNTVEFIGRHFDIGPADRCLALSTLEGDISVMDVFVTLRTGGSIVVVDEVQRRDPDAWAR 777 Query 776 LIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAG 835 LID ++VT L+FMPGWL+ML+EVG GRLSS+R V GGDWVRP++ RRL+V+AP RFAG Sbjct 778 LIDAHQVTVLHFMPGWLEMLVEVGRGRLSSVRVVPTGGDWVRPEVVRRLRVEAPGVRFAG 837 Query 836 LGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWV 895 LGGATET VH +IFEV + +P DW ++P+GVP PNNACRVV D+G DCPDWV GE WV Sbjct 838 LGGATETPVHNSIFEVTEP--IPDDWTALPFGVPLPNNACRVVDDTGADCPDWVPGEYWV 895 Query 896 SGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRV 955 SGRGIARGYRGRP+LTAERFVEHDGR WYRTGDL RYW DGTLEFVGRADHRVKISGYRV Sbjct 896 SGRGIARGYRGRPDLTAERFVEHDGRIWYRTGDLVRYWPDGTLEFVGRADHRVKISGYRV 955 Query 956 ELGEIEAALQRLPGVHAAAATVL--PGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHM 1013 ELGE+E AL+R+PGV A A ++ G SDVLAA VC DDA VTAE IRQ LADLVPAHM Sbjct 956 ELGEVETALRRVPGVRTAVAALIAVSGESDVLAAQVCADDASVTAEGIRQALADLVPAHM 1015 Query 1014 IPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADI 1073 IPRH+T+++RI FTD+GK+DR V L + V +S + + AP T LQ AL IV D+ Sbjct 1016 IPRHITVVERIGFTDAGKLDRRAVARELESAVSQS--QRPGHRAPSTPLQSALATIVGDL 1073 Query 1074 LGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTG 1133 LGR N +G+ DDFFALGGDSVLATQ VA IR WLD+P +MVAD+FA RT++ALA +L Sbjct 1074 LGRQN--IGIDDDFFALGGDSVLATQAVARIRAWLDAPDIMVADIFANRTVSALAAVLGA 1131 Query 1134 REANADRLELVAEVYLEIANMTSADVMAALDPIEQPAQ 1171 E + RL+ VAE+YLE+ M + V+AA +QPA+ Sbjct 1132 GERDPGRLDQVAELYLEVIGMDAESVLAA---SQQPAK 1166 >gi|289750983|ref|ZP_06510361.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis T92] gi|289691570|gb|EFD58999.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis T92] Length=799 Score = 1590 bits (4116), Expect = 0.0, Method: Compositional matrix adjust. Identities = 797/799 (99%), Positives = 799/799 (100%), Gaps = 0/799 (0%) Query 616 VAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVRVPVPTLLLADVL 675 +AAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVRVPVPTLLLADVL Sbjct 1 MAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVRVPVPTLLLADVL 60 Query 676 AAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGAADRWL 735 AAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAH+AAMNTVETFIRHFELGAADRWL Sbjct 61 AAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHNAAMNTVETFIRHFELGAADRWL 120 Query 736 ALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDML 795 ALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDML Sbjct 121 ALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDML 180 Query 796 LEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQDAA 855 LEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQDAA Sbjct 181 LEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQDAA 240 Query 856 NLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAERF 915 NLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAERF Sbjct 241 NLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAERF 300 Query 916 VEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAAAA 975 VEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAAAA Sbjct 301 VEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAAAA 360 Query 976 TVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRA 1035 TVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRA Sbjct 361 TVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRA 420 Query 1036 EVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSV 1095 EVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSV Sbjct 421 EVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSV 480 Query 1096 LATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLEIANMT 1155 LATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLEIANMT Sbjct 481 LATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVYLEIANMT 540 Query 1156 SADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAAAYRWLAKSLVANDV 1215 SADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAAAYRWLAKSLVANDV Sbjct 541 SADVMAALDPIEQPAQPAFKPWVKRFTGTDKPGAVLVFPHAGGAAAAYRWLAKSLVANDV 600 Query 1216 DTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGHCMGAIVAFEFARLA 1275 DTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGHCMGAIVAFEFARLA Sbjct 601 DTFVVQYPQRADRRSHPAADSIEALALELFEAGDWHLTAPLTLFGHCMGAIVAFEFARLA 660 Query 1276 ERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELLVP 1335 ERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELLVP Sbjct 661 ERNGVPVRALWASSGQAPSTVAASGPLPTADRDVLADMVDLGGTDPVLLEDEEFVELLVP 720 Query 1336 AVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDGGH 1395 AVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDGGH Sbjct 721 AVKADYRALSGYSCPPDVRIRANIHAVGGNRDHRISREMLTSWETHTSGRFTLSHFDGGH 780 Query 1396 FYLNDHLDAVARMVSADVR 1414 FYLNDHLDAVARMVSADVR Sbjct 781 FYLNDHLDAVARMVSADVR 799 >gi|118464419|ref|YP_881228.1| MbtB protein [Mycobacterium avium 104] gi|118165706|gb|ABK66603.1| MbtB protein [Mycobacterium avium 104] Length=1164 Score = 1560 bits (4039), Expect = 0.0, Method: Compositional matrix adjust. Identities = 841/1174 (72%), Positives = 951/1174 (82%), Gaps = 18/1174 (1%) Query 2 VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATL 61 +HA A SE IR EVAELLGV DA+ PG+NL+GQGLDSIR+M+L GRWRR+GIAVDFATL Sbjct 1 MHAPARSEDIREEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRRGIAVDFATL 60 Query 62 AATPTIEAWSQLVSAG---TGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQ 118 A TPTIEAW+QLV+AG T A +PGD S E EPF LAPMQHAMWVGR D+QQ Sbjct 61 AETPTIEAWAQLVTAGRQDTDSAAPPADSPGDP--SGENEPFALAPMQHAMWVGRQDNQQ 118 Query 119 LGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPIS 178 LGGVAGHLYVEFD +DP RLRAAAT LA RHPMLRV+FLPDGTQRI PA DFP+ Sbjct 119 LGGVAGHLYVEFDAGLLDPGRLRAAATALARRHPMLRVRFLPDGTQRITPAVECGDFPVH 178 Query 179 VADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMS 238 V DLR + D V++RL +R+AKSHQQLDGAVFEL +TLLPG R+RLHVDLDMQAADAMS Sbjct 179 VEDLRELGTDEVERRLTALREAKSHQQLDGAVFELTVTLLPGGRSRLHVDLDMQAADAMS 238 Query 239 YRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPP 298 YR L+ADLAALY G + P L YTYR+YR A+EA++ PQP RDADRDWWA+R+P+LPDPP Sbjct 239 YRTLMADLAALYRGCDLPELSYTYRQYRHAVEAQDAQPQPRRDADRDWWARRLPELPDPP 298 Query 299 ALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASS 358 ALP AG R RSTRRWHWLDPQTRDALFARA+ARGITPAM LAA FAN LARWS++S Sbjct 299 ALPITAG--RGANRSTRRWHWLDPQTRDALFARAQARGITPAMALAAGFANTLARWSSNS 356 Query 359 RFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSA 418 RFLLN+PLF RQ LHPDVD LVGDFTSSLLLDVDL GA TAAARAQ VQ+A+R+AA HSA Sbjct 357 RFLLNVPLFGRQPLHPDVDALVGDFTSSLLLDVDLVGAHTAAARAQVVQDAMRTAAAHSA 416 Query 419 YPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQ 478 Y GLSVLRDLSRHRGTQVLAPVVFTSALGLG+LF P+VT+QFGTP WIISQGPQVLLDAQ Sbjct 417 YSGLSVLRDLSRHRGTQVLAPVVFTSALGLGELFSPEVTDQFGTPAWIISQGPQVLLDAQ 476 Query 479 VTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAV 538 VTEFDGGVLVNWDVREG F PGVIDAMF + +DELLRLA+ DDAWDAP P+ALP AQRAV Sbjct 477 VTEFDGGVLVNWDVREGFFPPGVIDAMFAYHIDELLRLASADDAWDAPGPAALPEAQRAV 536 Query 539 RAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAG 598 R A+NGRTA PS EALHDGFFRQA++QPDAPAVFA SGDLSYAQLRDQA AVAAAL AAG Sbjct 537 REAINGRTAPPSGEALHDGFFRQAERQPDAPAVFAGSGDLSYAQLRDQALAVAAALCAAG 596 Query 599 LRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGP 658 GDTVAV+GPK+ EQ+ AVLGIL+ G YLPIG DQPRDRAERIL +G V LALVCG Sbjct 597 AGAGDTVAVVGPKSAEQIPAVLGILSVGAAYLPIGADQPRDRAERILQSGRVRLALVCG- 655 Query 659 PCQVRVPVPTLLLADVLAAAP--AEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAM 716 Q+ +PVP L+LADVL AP AE DP LAYVLFTSGSTGEPKGVEV HDAAM Sbjct 656 GRQLSLPVPGLVLADVLGGAPADAEIACARVDPGELAYVLFTSGSTGEPKGVEVTHDAAM 715 Query 717 NTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARL 776 NTVE RHFE+G ADR LAL+TLE D+SV+D+F LR+GGAIVVVDEAQRRDPDAWARL Sbjct 716 NTVEFIGRHFEIGPADRCLALSTLEGDISVMDVFVTLRTGGAIVVVDEAQRRDPDAWARL 775 Query 777 IDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGL 836 IDT+ VT L+FMPGWL+ML+EVG GRLSS+R V GGDWVRP++ RRL+ +AP RFAGL Sbjct 776 IDTHRVTVLHFMPGWLEMLVEVGRGRLSSVRVVPTGGDWVRPEVVRRLRAEAPGLRFAGL 835 Query 837 GGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVS 896 GGATET VH TIFEV + +P D ++P+GVP PNN CRVV D+G DCPDWV GELWVS Sbjct 836 GGATETPVHNTIFEVTEP--IPADCTALPFGVPLPNNVCRVVGDTGGDCPDWVPGELWVS 893 Query 897 GRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVE 956 GRGIARGYRGRP+LTA+RFVEHDGRTWYRTGDL RY DGTLEFVGRADHRVKISGYRVE Sbjct 894 GRGIARGYRGRPDLTAQRFVEHDGRTWYRTGDLVRYRPDGTLEFVGRADHRVKISGYRVE 953 Query 957 LGEIEAALQRLPGVHAAAATVLPGG--SDVLAAAVCVDDAGVTAESIRQQLADLVPAHMI 1014 LGEIE+AL+R+PGV A A ++ G SDVLAA V DD +T E +RQ LADLVPAHMI Sbjct 954 LGEIESALRRVPGVRTAVAALIAGAGESDVLAAQVGTDDPALTGEQVRQYLADLVPAHMI 1013 Query 1015 PRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADIL 1074 PRHV +++RI FT +GK+DR V L + V +S RS + A T L+ AL I+ D+L Sbjct 1014 PRHVEVVERIGFTAAGKLDRRAVARELHSVVGQS--RSPGHRAASTPLEGALALILGDLL 1071 Query 1075 GRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGR 1134 GR + V FFALGGDSVLATQ VA IR WLD+P +MVAD+FA RT++ALA +L Sbjct 1072 GRDDVGVDDD--FFALGGDSVLATQAVARIRAWLDAPDVMVADIFANRTVSALAAVLRAA 1129 Query 1135 EANADRLELVAEVYLEIANMTSADVMAALDPIEQ 1168 E + DRL+ VAE+YLE+ M + V+AA I + Sbjct 1130 EDDPDRLDHVAELYLEVIGMDAESVLAATRQITK 1163 >gi|336458162|gb|EGO37145.1| amino acid adenylation enzyme/thioester reductase family protein [Mycobacterium avium subsp. paratuberculosis S397] Length=1164 Score = 1550 bits (4014), Expect = 0.0, Method: Compositional matrix adjust. Identities = 837/1167 (72%), Positives = 945/1167 (81%), Gaps = 16/1167 (1%) Query 2 VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATL 61 +HA A SE IR EVAELLGV DA+ PG+NL+GQGLDSIR+M+L GRWRR+GIAVDFATL Sbjct 1 MHAPARSEDIREEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRRGIAVDFATL 60 Query 62 AATPTIEAWSQLVSAGTGVAPTAVAAPGDAG--LSQEGEPFPLAPMQHAMWVGRHDHQQL 119 A TPTIEAW+QLV+AG +A A P D+ S E EPF LAPMQHAMWVGR D+QQL Sbjct 61 AETPTIEAWAQLVTAGRQDTDSA-APPADSSGDPSGENEPFALAPMQHAMWVGRQDNQQL 119 Query 120 GGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISV 179 G VAGHLYVEFD +D RLRAAAT LA RHPMLRV+FLPDGTQ I PA DFP+ V Sbjct 120 GEVAGHLYVEFDAGLLDSGRLRAAATALARRHPMLRVRFLPDGTQCITPAVECGDFPVHV 179 Query 180 ADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSY 239 DLR + D V++RL +R+AKSHQQLDGAVFEL +TLLPG R+RLHVDLDMQAADAMSY Sbjct 180 EDLRELGTDEVERRLTALREAKSHQQLDGAVFELTVTLLPGGRSRLHVDLDMQAADAMSY 239 Query 240 RILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPA 299 R L+ADLAALY G + P L YTYR+YR A+EA++ PQP RDADRDWWA+R+P+LPDPPA Sbjct 240 RTLMADLAALYRGCDLPELSYTYRQYRHAVEAQDAQPQPRRDADRDWWARRLPELPDPPA 299 Query 300 LPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSR 359 LP AG R RSTRRWHWLDPQTRDALFARA+ARGITPAM LAA FAN LARWS++SR Sbjct 300 LPITAG--RGANRSTRRWHWLDPQTRDALFARAQARGITPAMALAAGFANTLARWSSNSR 357 Query 360 FLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAY 419 FLLN+PLF RQ LHPDVD LVGDFTSSLLLDVDL GA TAAARAQ VQ+A+R+AA HSAY Sbjct 358 FLLNVPLFGRQPLHPDVDALVGDFTSSLLLDVDLVGAHTAAARAQVVQDAMRTAAAHSAY 417 Query 420 PGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQV 479 GLSVLRDLSRHRGTQVLAPVVFTSALGLG+LF P+VT QFGTP WIISQGPQVLLDAQV Sbjct 418 SGLSVLRDLSRHRGTQVLAPVVFTSALGLGELFSPEVTGQFGTPAWIISQGPQVLLDAQV 477 Query 480 TEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVR 539 TEFDGGVLVNWDVREG F PGVIDAMF + +DELLRLA+ DDAWDAP P+ALP AQRAVR Sbjct 478 TEFDGGVLVNWDVREGFFPPGVIDAMFAYHIDELLRLASADDAWDAPGPAALPEAQRAVR 537 Query 540 AALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGL 599 A+NGRTA PS EALHDGFFRQA++QPDAPAVFA SGDLSYAQLRDQA AVAAALRAAG Sbjct 538 EAINGRTAPPSGEALHDGFFRQAERQPDAPAVFAGSGDLSYAQLRDQALAVAAALRAAGA 597 Query 600 RVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPP 659 GDTVAV+GPK+ EQ+ AVLGIL+ G YLPIG DQPRDRAERIL +G V LALVCG Sbjct 598 GAGDTVAVVGPKSAEQIPAVLGILSVGAAYLPIGADQPRDRAERILQSGRVRLALVCG-G 656 Query 660 CQVRVPVPTLLLADVLAAAP--AEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMN 717 Q+ +PVP L+LADVL AP AE DP LAYVLFTSGSTGEPKGVEV HDAAMN Sbjct 657 RQLSLPVPGLVLADVLGGAPADAEIACARVDPGELAYVLFTSGSTGEPKGVEVTHDAAMN 716 Query 718 TVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLI 777 TVE RHFE+G ADR LAL+TLE D+SV+D+F LR+GGAIVVVDEAQRRDPDAWARLI Sbjct 717 TVEFIGRHFEIGPADRCLALSTLEGDISVMDVFVTLRTGGAIVVVDEAQRRDPDAWARLI 776 Query 778 DTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLG 837 DT+ VT L+FMPGWL+ML+EVG GRLSS+R V GGDWVRP++ RRL+ +AP RFAGLG Sbjct 777 DTHRVTVLHFMPGWLEMLVEVGRGRLSSVRVVPTGGDWVRPEVVRRLRAEAPGLRFAGLG 836 Query 838 GATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSG 897 GATET VH TIFEV + +P DW ++P+GVP PNN CRVV D+G DCPDWV GELWVSG Sbjct 837 GATETPVHNTIFEVTEP--IPADWTALPFGVPLPNNVCRVVGDTGGDCPDWVPGELWVSG 894 Query 898 RGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVEL 957 RGIARGYRGRP+LTA+RFVEHDGRTWYRTGDL RY DGTLEFVGRADHRVKISGYRVEL Sbjct 895 RGIARGYRGRPDLTAQRFVEHDGRTWYRTGDLVRYRPDGTLEFVGRADHRVKISGYRVEL 954 Query 958 GEIEAALQRLPGVHAAAATVLPGG--SDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIP 1015 GEIE+AL+R+PGV A A ++ G SDVLAA V DD +T E +RQ LADLVPAHMIP Sbjct 955 GEIESALRRVPGVRTAVAALIAGAGESDVLAAQVGTDDPALTGEQVRQYLADLVPAHMIP 1014 Query 1016 RHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILG 1075 RHV +++RI FT +GK+DR V L + V +S S + A T L+ AL I+ D+LG Sbjct 1015 RHVAVVERIGFTAAGKLDRRAVARELHSVVGQS--HSPGHRAASTPLEGALALILGDLLG 1072 Query 1076 RANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGRE 1135 R + V FFALGGDSVLATQ VA IR WLD+P +MVADMFA RT++ALA +L E Sbjct 1073 RDDVGVDDD--FFALGGDSVLATQAVARIRAWLDAPDVMVADMFANRTVSALAAVLRAAE 1130 Query 1136 ANADRLELVAEVYLEIANMTSADVMAA 1162 + DRL+ VAE+YLE+ M + V+ A Sbjct 1131 DDPDRLDHVAELYLEVIGMDAESVLTA 1157 >gi|41408275|ref|NP_961111.1| MbtB [Mycobacterium avium subsp. paratuberculosis K-10] gi|81413928|sp|Q73XY1.1|MBTB_MYCPA RecName: Full=Phenyloxazoline synthase MbtB; AltName: Full=Mycobactin synthetase protein B gi|41396630|gb|AAS04494.1| MbtB [Mycobacterium avium subsp. paratuberculosis K-10] Length=1165 Score = 1544 bits (3997), Expect = 0.0, Method: Compositional matrix adjust. Identities = 836/1168 (72%), Positives = 945/1168 (81%), Gaps = 16/1168 (1%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHA A SE IR EVAELLGV DA+ PG+NL+GQGLDSIR+M+L GRWRR+GIAVDFAT Sbjct 1 MVHAPARSEDIREEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRRGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAG--LSQEGEPFPLAPMQHAMWVGRHDHQQ 118 LA TPTIEAW+QLV+AG +A A P D+ S E EPF LAPMQHAMWVGR D+QQ Sbjct 61 LAETPTIEAWAQLVTAGRQDTDSA-APPADSSGDPSGETEPFALAPMQHAMWVGRQDNQQ 119 Query 119 LGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPIS 178 LGGVAGHLYVEFD +D RLRAAAT LA RHPMLRV+FLPDGTQ I PA DFP+ Sbjct 120 LGGVAGHLYVEFDAGLLDSGRLRAAATALARRHPMLRVRFLPDGTQCITPAVECGDFPVH 179 Query 179 VADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMS 238 V DLR + D V++RL +R+AKSHQQLDGAVFEL +TLLPG R+RLHVDLDMQAADAMS Sbjct 180 VEDLRELGTDEVERRLTALREAKSHQQLDGAVFELTVTLLPGGRSRLHVDLDMQAADAMS 239 Query 239 YRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPP 298 YR L+ADLAALY G + P L YTYR+YR A+EA++ PQP RDADRDWWA+R+P+LPDPP Sbjct 240 YRTLMADLAALYRGCDLPELSYTYRQYRHAVEAQDAQPQPRRDADRDWWARRLPELPDPP 299 Query 299 ALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASS 358 ALP AG R RSTRRWHWLDPQTRDALFARA+ARGITPAM LAA FAN LARWS++S Sbjct 300 ALPITAG--RGANRSTRRWHWLDPQTRDALFARAQARGITPAMALAAGFANTLARWSSNS 357 Query 359 RFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSA 418 RFLLN+PLF RQ LHPDVD LVGDFTSSLLLDVDL GA TAAARAQ VQ+A+R+AA HSA Sbjct 358 RFLLNVPLFGRQPLHPDVDALVGDFTSSLLLDVDLVGAHTAAARAQVVQDAMRTAAAHSA 417 Query 419 YPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQ 478 Y GLSVLRDLSRHRGTQVLAPVVFTSALGLG+LF P+VT QFGTP WIISQGPQVLLDAQ Sbjct 418 YSGLSVLRDLSRHRGTQVLAPVVFTSALGLGELFSPEVTGQFGTPAWIISQGPQVLLDAQ 477 Query 479 VTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAV 538 VTEFDGGVLVNWDVREG F PGVIDAMF + +DELLRLA+ DDAWDAP P+ALP AQRAV Sbjct 478 VTEFDGGVLVNWDVREGFFPPGVIDAMFAYHIDELLRLASADDAWDAPGPAALPEAQRAV 537 Query 539 RAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAG 598 R A+NGRTA PS EALHD FFRQA++QPDAPAVFA SGDLSYAQLRDQA AVAAALRAAG Sbjct 538 REAINGRTAPPSGEALHDRFFRQAERQPDAPAVFAGSGDLSYAQLRDQALAVAAALRAAG 597 Query 599 LRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGP 658 GDTVAV+GPK+ EQ+ AVLGIL+ G YLPIG DQPRDRAERIL +G V LALVCG Sbjct 598 AGAGDTVAVVGPKSAEQIPAVLGILSVGAAYLPIGADQPRDRAERILQSGRVRLALVCG- 656 Query 659 PCQVRVPVPTLLLADVLAAAP--AEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAM 716 Q+ +PVP L+LADVL AP AE DP LAYVLFTSGSTGEPKGVEV HDAAM Sbjct 657 GRQLSLPVPGLVLADVLGGAPADAEIACARVDPGELAYVLFTSGSTGEPKGVEVTHDAAM 716 Query 717 NTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARL 776 NTVE RHFE+G ADR LAL+TLE D+SV+D+F LR+GGAIVVVDEAQRRDPDAWARL Sbjct 717 NTVEFIGRHFEIGPADRCLALSTLEGDISVMDVFVTLRTGGAIVVVDEAQRRDPDAWARL 776 Query 777 IDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGL 836 IDT+ VT L+FMPGWL+ML+EVG GRLSS+R V GGDWVRP++ RRL+ +AP RFAGL Sbjct 777 IDTHRVTVLHFMPGWLEMLVEVGRGRLSSVRVVPTGGDWVRPEVVRRLRAEAPGLRFAGL 836 Query 837 GGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVS 896 GGATET VH TIFEV + +P DW ++P+GVP PNN CRVV D+G DCP+WV GELWVS Sbjct 837 GGATETPVHNTIFEVTEP--IPADWTALPFGVPLPNNVCRVVGDTGGDCPEWVPGELWVS 894 Query 897 GRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVE 956 GRGIARGYRGRP+LTA+RFVEHDGRT YRTGDL RY DGTLEFVGRADHRVKISGYRVE Sbjct 895 GRGIARGYRGRPDLTAQRFVEHDGRTSYRTGDLVRYRPDGTLEFVGRADHRVKISGYRVE 954 Query 957 LGEIEAALQRLPGVHAAAATVLPGG--SDVLAAAVCVDDAGVTAESIRQQLADLVPAHMI 1014 LGEIE+AL+R+PGV A A ++ G SDVLAA V DD +T E +RQ LADLVPAHMI Sbjct 955 LGEIESALRRVPGVRTAVAALIAGAGESDVLAAQVGTDDPALTGEQVRQYLADLVPAHMI 1014 Query 1015 PRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADIL 1074 PRHV +++RI FT +GK+DR V L + V +S S + A T L+ AL I+ D+L Sbjct 1015 PRHVAVVERIGFTAAGKLDRRAVARELHSVVGQS--HSPGHRAASTPLEGALALILGDLL 1072 Query 1075 GRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGR 1134 GR + V FFALGGDSVLATQ VA IR WLD+P +MVADMFA RT++ALA +L Sbjct 1073 GRDDVGVDDD--FFALGGDSVLATQAVARIRAWLDAPDVMVADMFANRTVSALAAVLRAA 1130 Query 1135 EANADRLELVAEVYLEIANMTSADVMAA 1162 E + DRL+ VAE+YLE+ M + V+ A Sbjct 1131 EDDPDRLDHVAELYLEVIGMDAESVLTA 1158 >gi|296170578|ref|ZP_06852162.1| mycobactin biosynthesis enzyme MbtB [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894810|gb|EFG74535.1| mycobactin biosynthesis enzyme MbtB [Mycobacterium parascrofulaceum ATCC BAA-614] Length=1177 Score = 1535 bits (3974), Expect = 0.0, Method: Compositional matrix adjust. Identities = 839/1171 (72%), Positives = 950/1171 (82%), Gaps = 15/1171 (1%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 VV A+A SE +RAEVAELLGV D +HP NL+GQGLDSIRMM+L GRWRR+GI VDFAT Sbjct 8 VVRASARSEDVRAEVAELLGVEVDDVHPDTNLIGQGLDSIRMMTLAGRWRRRGIPVDFAT 67 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWS LV+A A P AG EPFPLAPMQHAMWVGR D+QQLG Sbjct 68 LAATPTIEAWSGLVTAADAPAEDTERPPAGAGDDAAAEPFPLAPMQHAMWVGRQDNQQLG 127 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDG +DP RLRAAAT LA RHPMLRV+FLPDGTQRI AA FP++V Sbjct 128 GVAGHLYVEFDGGPIDPGRLRAAATALARRHPMLRVEFLPDGTQRI--AARGDAFPVAVE 185 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRH+ D VD+RLA +R+ +SHQQLDGAVFELALT LPGER+RLHVDLDMQAADAMSYR Sbjct 186 DLRHLGADEVDRRLAALRETRSHQQLDGAVFELALTRLPGERSRLHVDLDMQAADAMSYR 245 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 L+ADLA LY G PAL Y+YR+YR+A+EA+E PQP RD R+WWAQRIPQLPDPP+L Sbjct 246 TLMADLATLYRGHHLPALDYSYRQYRRAVEADEARPQPARDTARNWWAQRIPQLPDPPSL 305 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PT G+R RRS R WHWLDP+TRDALF+RARARG+TPAMTLAA+F++ LARWS SSRF Sbjct 306 PTT--GDRGSRRSVRLWHWLDPETRDALFSRARARGLTPAMTLAASFSHALARWSTSSRF 363 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLN+PLF RQ LHPDVD LVGDFTSSLLLDVDLTG TAA RA AVQ+A+R+AA H+AYP Sbjct 364 LLNVPLFGRQPLHPDVDSLVGDFTSSLLLDVDLTGLPTAAERAAAVQDAMRTAAAHAAYP 423 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLG LF +VT QFGTP WIISQGPQVLLDAQVT Sbjct 424 GLSVLRDLSRHRGTQVLAPVVFTSALGLGPLFGDEVTAQFGTPAWIISQGPQVLLDAQVT 483 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 E DGGVLVNWDVREGVFAPGVIDAMF + +DELLRLA+ D+ WDAP PS LPAAQRAVR Sbjct 484 ELDGGVLVNWDVREGVFAPGVIDAMFAYHIDELLRLASADEDWDAPGPSPLPAAQRAVRD 543 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 +NGRTA PS EALHDGFFRQA+ +PDAPAV A SGDLSYAQLRD+A AVAAALR AG+ Sbjct 544 RVNGRTAEPSGEALHDGFFRQAELRPDAPAVLAGSGDLSYAQLRDRALAVAAALRGAGVG 603 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 GDTVAV+GPKT EQV A+LGIL+ G VYLPIGVDQPRDRA+RIL TG V LALVCG Sbjct 604 AGDTVAVMGPKTAEQVPALLGILSIGAVYLPIGVDQPRDRADRILQTGGVRLALVCG-GQ 662 Query 661 QVRVPVPTLLLADVL--AAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNT 718 ++ +PVP L LA+VL AA E +P LAYVLFTSGSTGEPKGVEV HDAAMNT Sbjct 663 RLDLPVPELTLAEVLRGAAITTEIPSVRVEPAQLAYVLFTSGSTGEPKGVEVTHDAAMNT 722 Query 719 VETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLID 778 VE RHFE+G DR LAL+TLE D+SV+D+F LR+GG+IVVVDEAQRRDPDAWARLID Sbjct 723 VEFIARHFEIGPGDRCLALSTLEGDISVMDVFVTLRTGGSIVVVDEAQRRDPDAWARLID 782 Query 779 TYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGG 838 T+ VT L+FMPGWL+ML+EVG GRLSS+R + GGDWVRP+LARRL+ +AP+ RFAGLGG Sbjct 783 THRVTVLHFMPGWLEMLIEVGHGRLSSVRVIPTGGDWVRPELARRLRAEAPNLRFAGLGG 842 Query 839 ATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGR 898 ATET VH TIFEV D LP D ++PYGVP PNNACRVV D+GDDCPDWVAGELWVSGR Sbjct 843 ATETPVHNTIFEVIDPEGLPADSTALPYGVPLPNNACRVVDDAGDDCPDWVAGELWVSGR 902 Query 899 GIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELG 958 GIARGYRGRP+LTA+RFVE GR WYRTGDLARYW DGTLEFVGRADHRVKISGYRVELG Sbjct 903 GIARGYRGRPDLTADRFVERAGRRWYRTGDLARYWPDGTLEFVGRADHRVKISGYRVELG 962 Query 959 EIEAALQRLPGVHAAAATVL--PGGSDVLAAAVCVDDAG--VTAESIRQQLADLVPAHMI 1014 E+EAA++RLPGV A A +L PGGS++LAAAVC + +G + AE +R+ +A+L+PAHMI Sbjct 963 EVEAAMRRLPGVAIAVAALLPGPGGSEMLAAAVCPESSGADLAAERVRELMAELLPAHMI 1022 Query 1015 PRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADIL 1074 PRHV L+ RIPFTD+GKIDR V LAA V S +R AP +P T L+ AL ++ +L Sbjct 1023 PRHVALVRRIPFTDAGKIDRRAVARDLAAAVAAS-ERPAPR-SPATPLESALAALLGGLL 1080 Query 1075 GRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGR 1134 D VG DDFFALGGDSVLATQ V IR WLD+P + VAD+FA RT+AALA LL R Sbjct 1081 --GADTVGRDDDFFALGGDSVLATQAVGRIRTWLDAPHVAVADVFATRTVAALAALLVDR 1138 Query 1135 EANADRLELVAEVYLEIANMTSADVMAALDP 1165 E RL+ VAE+YLE+ M + V++A P Sbjct 1139 EGGGARLDQVAELYLEVIEMDADTVLSASRP 1169 >gi|333990169|ref|YP_004522783.1| phenyloxazoline synthase MbtB [Mycobacterium sp. JDM601] gi|333486137|gb|AEF35529.1| phenyloxazoline synthase MbtB [Mycobacterium sp. JDM601] Length=1175 Score = 1379 bits (3569), Expect = 0.0, Method: Compositional matrix adjust. Identities = 783/1172 (67%), Positives = 895/1172 (77%), Gaps = 25/1172 (2%) Query 8 SEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTI 67 S+ +R EVAELLGV D + P +L+ GLDSIRMMSL GRWR++GI VDFATLAA PT+ Sbjct 8 SQSVRDEVAELLGVSPDTIDPAQDLIASGLDSIRMMSLSGRWRKRGIDVDFATLAADPTV 67 Query 68 EAWSQLVSAGTGVAPTAVAAP-GDAGLSQEG---EPFPLAPMQHAMWVGRHDHQQLGGVA 123 AWS LV+A A AAP G A + G PFPLAP+QHA WVGR+D QQLGGVA Sbjct 68 AAWSDLVAAHAPGADALDAAPDGGASSADHGGPAAPFPLAPLQHAYWVGRNDQQQLGGVA 127 Query 124 GHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLR 183 HLYVEFDG VDP RL AAA LA+RHPMLRV+ + DGTQRI G R+ P+ ++DLR Sbjct 128 AHLYVEFDGTGVDPGRLAAAAAELAVRHPMLRVEIMSDGTQRI----GDRELPVKISDLR 183 Query 184 HVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILL 243 + + V+++L R+AKSHQ LDG V EL+L+LLPG RTRLHVDLDMQA DA+SYR + Sbjct 184 ELDAEAVERQLLATREAKSHQLLDGEVLELSLSLLPGGRTRLHVDLDMQAGDAVSYRRFM 243 Query 244 ADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDA-DRDWWAQRIPQLPDPPALPT 302 +DLA LY G PP L YTYREYR A+ E R A D+ WW++RIP LP PP+LP Sbjct 244 SDLAVLYAGGTPPQLDYTYREYRAAMSRLEA----ARSAQDQPWWSERIPSLPGPPSLPL 299 Query 303 RAGGER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFL 361 E+ D RRS RRWHW D R+ALFA AR+ G+TPAM AA++A LARWS S RFL Sbjct 300 VPTSEQSDPRRSVRRWHWFDAAAREALFAAARSHGVTPAMAFAASYAGTLARWSTSRRFL 359 Query 362 LNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPG 421 LNLP+F R+ HP VD+LVGDFTSSL+LDVDLT A + +RA AVQ+AL S+A H Y G Sbjct 360 LNLPMFGREPFHPQVDMLVGDFTSSLMLDVDLTQADSPLSRAVAVQQALHSSARHLGYSG 419 Query 422 LSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTE 481 LSVLRDLSRHRG Q LAP VFTS LGLGDLF +VTE FG P W ISQGPQVLLDAQVT Sbjct 420 LSVLRDLSRHRGVQTLAPFVFTSGLGLGDLFGGEVTEIFGAPVWTISQGPQVLLDAQVTP 479 Query 482 FDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAA 541 GG+LVNWDVRE F PGV+DAMF HQ+DEL RLA DAW P +P +QR VRAA Sbjct 480 LGGGLLVNWDVREEAFQPGVVDAMFGHQLDELHRLA-DPDAWTTPDSPEVPESQRVVRAA 538 Query 542 LNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRV 601 +N A PS EALH GFFRQA++QPDAPAVFA SGDLSY QLRDQA AVAAALRA G+R Sbjct 539 VNSTVAGPSGEALHTGFFRQAERQPDAPAVFARSGDLSYRQLRDQALAVAAALRAEGVRA 598 Query 602 GDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQ 661 GDT+AVLGPK EQV AVLGILAAG VYLPIG DQPR+RAER+L TGSV LAL+ G Q Sbjct 599 GDTIAVLGPKNAEQVPAVLGILAAGAVYLPIGADQPRERAERLLQTGSVRLALLSGA-QQ 657 Query 662 VRVPVPTLLLADVLAA--APAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTV 719 VP L LA+VL+ +P E + SDP ALAYVLFTSGSTGEPKGVE+ HDA MNTV Sbjct 658 TPSSVPALRLAEVLSGPTSPDESISVASDPEALAYVLFTSGSTGEPKGVELTHDAVMNTV 717 Query 720 ETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDT 779 E +RHF++GA+DRWL+LATLE DMSV DIFA LR+GGAIVVVDE QRRDPDAWA LI Sbjct 718 EFLLRHFDIGASDRWLSLATLESDMSVPDIFANLRAGGAIVVVDEDQRRDPDAWASLIHA 777 Query 780 YEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGA 839 + VTALNFMPGWL+MLL VG GRLSSLRAVAVGGDWVRP+LARRL++QAP ARFAGLGGA Sbjct 778 HRVTALNFMPGWLEMLLAVGDGRLSSLRAVAVGGDWVRPELARRLRLQAPRARFAGLGGA 837 Query 840 TETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRG 899 TETAVHATIFEV +AA L P+ +SVPYGVP PN ACRVV++SG DCPDWV GELWV+GRG Sbjct 838 TETAVHATIFEVDEAAGLLPNGSSVPYGVPLPNMACRVVSESGSDCPDWVIGELWVTGRG 897 Query 900 IARGYRGRPELTAERFVEHD----GRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRV 955 IARGYRGRP+LT ERFVE+ R+WYRTGDLARYW DGTLEFVGRADHR KISGYRV Sbjct 898 IARGYRGRPDLTGERFVEYPLHGVTRSWYRTGDLARYWPDGTLEFVGRADHRTKISGYRV 957 Query 956 ELGEIEAALQRLPG--VHAAAATVLPGGSDVLAAAVCV-DDAGVTAESIRQQLADLVPAH 1012 ELGE+EAAL R+PG AA GGSD LAA V V DD+G+TA IR L DLVPAH Sbjct 958 ELGEVEAALGRIPGVHAAVAAVLPAAGGSDGLAALVRVDDDSGLTAGRIRDALIDLVPAH 1017 Query 1013 MIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVAD 1072 MIPR ++ +DRIPFTD GKIDRA V L E + G + PR+ L+RAL IVA Sbjct 1018 MIPRWISPVDRIPFTDGGKIDRAAVACRLDQEFGQLGGATGSVTGPRSTLERALCHIVAG 1077 Query 1073 ILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLT 1132 +LGR DA+ VHDDFF+LGGDSVLAT+ VA IR WLDSP MV+DMFAART+AALA++L Sbjct 1078 VLGRDGDAMDVHDDFFSLGGDSVLATKAVAEIRVWLDSPRTMVSDMFAARTVAALAEVLI 1137 Query 1133 GREANADRLELVAEVYLEIANMTSADVMAALD 1164 GRE++ R+E VAE YLE+A M+ ADVM ALD Sbjct 1138 GRESDTGRMESVAEAYLEVAAMSEADVMVALD 1169 >gi|118469771|ref|YP_888787.1| non-ribosomal peptide synthetase [Mycobacterium smegmatis str. MC2 155] gi|118171058|gb|ABK71954.1| putative non-ribosomal peptide synthetase [Mycobacterium smegmatis str. MC2 155] Length=1169 Score = 1352 bits (3498), Expect = 0.0, Method: Compositional matrix adjust. Identities = 731/1174 (63%), Positives = 863/1174 (74%), Gaps = 27/1174 (2%) Query 4 ATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAA 63 A A S+ IRA VA+LLG+ ++A+ P A+L+GQGLDSIRMMSL GRWR++GI +DFATLAA Sbjct 5 AGANSQTIRAAVADLLGIGSEAVDPDADLIGQGLDSIRMMSLAGRWRQQGIDIDFATLAA 64 Query 64 TPTIEAWSQLVSAGTGVAPTAVAA----PGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQL 119 PT+ W++L++A + + + A P +AG Q G PFPLAPMQHAMWVGR D QQL Sbjct 65 NPTVSDWARLIAARSADSKASSAHANSRPSEAG-EQAGAPFPLAPMQHAMWVGREDDQQL 123 Query 120 GGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISV 179 GGVAGHLYVEFDG VDP+RLR AAT LA RHPMLRV+FLPDGTQRI A + +FP++V Sbjct 124 GGVAGHLYVEFDGTGVDPERLRRAATALAERHPMLRVEFLPDGTQRI--GAPANEFPVTV 181 Query 180 ADLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSY 239 DLR PD V +RL+ I+ AKSHQQL G VFEL L+LLP TRLHVDLDMQA DAMSY Sbjct 182 EDLRTATPDEVARRLSEIQRAKSHQQLQGEVFELTLSLLPSGATRLHVDLDMQAGDAMSY 241 Query 240 RILLADLAALYD-GREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPP 298 R L+ADLAALY+ G PALGYTYREYR +E E P DAD+ WWA+RIP LPDPP Sbjct 242 RTLMADLAALYNSGTSLPALGYTYREYR--LETPEG--GPAHDADQKWWAERIPDLPDPP 297 Query 299 ALPTRAGGER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSAS 357 LP E+ D +TRR HWLDPQTRDALFA AR RGITPAM LAA+FA VLA WSA Sbjct 298 RLPLIPVAEQADPHHTTRRHHWLDPQTRDALFAAARKRGITPAMALAASFAEVLAGWSAD 357 Query 358 SRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHS 417 RFLLN+PLF R+ HPDVD ++GDFTSSLLLD+DLT T RA+ VQ+ R+AAGH+ Sbjct 358 QRFLLNVPLFGREQRHPDVDKIIGDFTSSLLLDIDLTDTTTPTQRAKVVQDTFRAAAGHA 417 Query 418 AYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDA 477 YPGLSVLRDL RHRGTQV+APVV+TSALGLG+LF +VT+ FG P WI SQGPQVLLDA Sbjct 418 NYPGLSVLRDLGRHRGTQVIAPVVYTSALGLGELFATEVTDAFGKPVWINSQGPQVLLDA 477 Query 478 QVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRA 537 QVTEFDGGVLVNWDVRE F PGVIDAMF + EL RLA D AWD PSP LP +QR Sbjct 478 QVTEFDGGVLVNWDVREDAFRPGVIDAMFARHIAELRRLATDDTAWDIPSPPLLPQSQRD 537 Query 538 VRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAA 597 VR A+N R+AAPS ALHDGFF QA +P A A+ S+G L+YA+LR+QA AVA ALR A Sbjct 538 VRDAVNARSAAPSGRALHDGFFEQAAMRPGAVALIGSNGPLTYAELREQALAVATALRVA 597 Query 598 GLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCG 657 G+R G++VAV+GPK +Q+ A+LGILAAG VY+P+GVDQP DRAER+LA V +AL CG Sbjct 598 GVRRGESVAVMGPKGPDQIPALLGILAAGAVYVPVGVDQPTDRAERMLADAGVRMALFCG 657 Query 658 PPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMN 717 +P T+ A ++ P + P LAYVLFTSGSTGEPKGVEV HDAAMN Sbjct 658 DGTPTWLPALTVTEAVLVGRRHETVEPVSAAPDDLAYVLFTSGSTGEPKGVEVTHDAAMN 717 Query 718 TVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLI 777 TVET +F G D LAL LE D+SVLD+F L +GG+IV+VDEA RR+PD W I Sbjct 718 TVETLNTYFGTGPGDSVLALTHLESDLSVLDVFGTLAAGGSIVMVDEADRRNPDHWVAQI 777 Query 778 DTYEVTALNFMPGWLDMLLEVGGGR---LSSLRAVAVGGDWVRPDLARRLQVQAPSARFA 834 + + VT LNF+PG L+ML+E + SLRAV GGDWVR + R+LQ +P Sbjct 778 NAHGVTTLNFLPGSLEMLVETAWSTRTPMPSLRAVPTGGDWVRTTMVRKLQQLSPGVVLT 837 Query 835 GLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELW 894 GLGGATETA+HAT+FE A LP W +VPYG PFPNNACRVV +G DCPDWV GELW Sbjct 838 GLGGATETAIHATLFE---AKELPEHWTAVPYGAPFPNNACRVVNAAGQDCPDWVPGELW 894 Query 895 VSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYR 954 + GRGIARGYRG+P+LTAE+FV GR WYRTGDLARYW DGTLEFVGRADHRVK+SGYR Sbjct 895 IGGRGIARGYRGKPDLTAEKFVTWCGRRWYRTGDLARYWPDGTLEFVGRADHRVKLSGYR 954 Query 955 VELGEIEAALQRLPGVHAAAATVL--PGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAH 1012 +ELGE+EAALQRLPGVHAA A ++ P G D+LAA V +DD VT +R LA+L+P H Sbjct 955 IELGEVEAALQRLPGVHAAVADIVDTPAG-DLLAAVVGLDDTSVTDADLRAGLAELLPPH 1013 Query 1013 MIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVE--RSGDRSAPYAAPRTVLQRALRRIV 1070 M+PRH L ++PFT GK DR V LLA VE ++G R P T L+RAL I+ Sbjct 1014 MVPRHFELTGKVPFTVGGKTDRRAVARLLAEAVEQAQAGGRGTAR-RPETSLERALAAIL 1072 Query 1071 ADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQL 1130 ++L A+ VG +DFF LGGDSVLAT VA IR WLD+P++MV D+FA RT+ LA Sbjct 1073 GELLSVAD--VGADEDFFELGGDSVLATAAVARIRDWLDTPTVMVPDIFATRTVEKLASR 1130 Query 1131 LTGREANADRLELVAEVYLEIANMTSADVMAALD 1164 L REA+ RLE VAE+YLE+A M A VM+ALD Sbjct 1131 LVAREADGSRLEQVAELYLEVAAMDDAAVMSALD 1164 >gi|126436059|ref|YP_001071750.1| amino acid adenylation domain-containing protein [Mycobacterium sp. JLS] gi|126235859|gb|ABN99259.1| amino acid adenylation domain [Mycobacterium sp. JLS] Length=1167 Score = 1292 bits (3343), Expect = 0.0, Method: Compositional matrix adjust. Identities = 715/1165 (62%), Positives = 843/1165 (73%), Gaps = 21/1165 (1%) Query 7 CSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPT 66 S+ +RAEVAELLG+ AL P A+L+ GLDSIRMMSL GRWR++GI V FA +AA PT Sbjct 7 SSQTVRAEVAELLGIEESALDPDADLIASGLDSIRMMSLSGRWRKQGIDVRFAAMAANPT 66 Query 67 IEAWSQLVSAGTGVAPTAVAAPGDAGLS--QEGEPFPLAPMQHAMWVGRHDHQQLGGVAG 124 + AW++LV T +P A GD S PFPLAP+QHA+WVGR++ +LGGVA Sbjct 67 VAAWTRLVGERTAESPGAATQSGDTAASAGDPDAPFPLAPIQHALWVGRNELTELGGVAA 126 Query 125 HLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRH 184 HLYVEFDGA VDP+RLR AA LA RHPMLRV L DG QRI RD P+ V DLRH Sbjct 127 HLYVEFDGAGVDPERLRTAAAALAARHPMLRVDILGDGMQRI----SDRDLPVKVTDLRH 182 Query 185 VAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLA 244 + +Q+L IR AKSHQ L+G V ELALTLLP RTRLHVDLDMQAADA+SYR +A Sbjct 183 LDVADAEQQLEVIRHAKSHQLLEGEVLELALTLLPDGRTRLHVDLDMQAADAVSYRNFMA 242 Query 245 DLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRA 304 DLAALY G + P L YTYR+YR A A P P D DR WW +RIP LP+PPALP Sbjct 243 DLAALYRGAQLPELQYTYRQYRSAFTAT---PAPTVDEDRRWWTERIPDLPEPPALPLVP 299 Query 305 GGE-RDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLN 363 E RD RR TRRWH+LD RD LFA ARARGITPAM AA++A LARWS S FLLN Sbjct 300 RAEQRDPRRGTRRWHFLDTDIRDRLFAAARARGITPAMAFAASYAGTLARWSTSRHFLLN 359 Query 364 LPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLS 423 LP+F R+ HPDVD LVGDFTSSL+LDVD T A T A RA+ +QEAL ++A H+ Y GLS Sbjct 360 LPMFGREPFHPDVDKLVGDFTSSLMLDVDFTEAHTPAQRARVMQEALHTSAEHATYSGLS 419 Query 424 VLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFD 483 VLRDLSRH G+ LAP VFTSALGLGDLF DVT+QFGTP W ISQGPQVLLDAQVT FD Sbjct 420 VLRDLSRHHGSPSLAPFVFTSALGLGDLFAGDVTDQFGTPVWHISQGPQVLLDAQVTPFD 479 Query 484 GGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALN 543 GG+LVNWDVRE F PGVIDAMF +Q+ EL RLAA D AWDA P A+P AQRAVR A+N Sbjct 480 GGLLVNWDVREDAFRPGVIDAMFAYQLAELERLAADDAAWDAADPPAVPPAQRAVRDAVN 539 Query 544 GRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRVGD 603 A S +ALHDGFFR A PDA AV S+G L+YA+LR++ AV AL+ AG++ GD Sbjct 540 DTGARRSDDALHDGFFRTAAHTPDATAVIGSTGTLTYAELRERVLAVTGALQVAGIKPGD 599 Query 604 TVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVR 663 TVAV+GPK +QV A+L I AAG VY+PIG DQP DRA+ IL T V +AL CG Sbjct 600 TVAVMGPKCADQVTALLAIHAAGAVYVPIGADQPADRADSILQTAGVRMALACGDEPPTF 659 Query 664 VPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVETFI 723 +P T+ A + + + P +P +AYVLFTSGSTG PKGVEV H AAMNT+E Sbjct 660 LPALTIAEAVRVGSRVHDVTPATVEPDRVAYVLFTSGSTGAPKGVEVTHAAAMNTLEFIN 719 Query 724 RHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVT 783 HF +G +DR LAL+TLE D+SVLD+F LR+GG++VVVDEAQRRDPD+WARLI + VT Sbjct 720 DHFGIGPSDRSLALSTLEGDLSVLDVFGMLRAGGSLVVVDEAQRRDPDSWARLIAEHSVT 779 Query 784 ALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETA 843 L++MPGWL+MLLEVGG L S+R V GGDWVR ++ R L+ A RFAGLGGATETA Sbjct 780 VLHWMPGWLEMLLEVGGA-LPSVRVVPTGGDWVRTEMVRELRRAATGVRFAGLGGATETA 838 Query 844 VHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARG 903 +H TI E LP +W++VP+G P PNNACRVVA G DCPDWV GELWV GRGIARG Sbjct 839 IHNTICE---PGELPREWSAVPFGRPLPNNACRVVAADGADCPDWVPGELWVGGRGIARG 895 Query 904 YRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAA 963 YRGRP+LTAERFV HDGRTWYRTGDL RY DG ++FVGRADHRVKISGYR+ELGE+EAA Sbjct 896 YRGRPDLTAERFVVHDGRTWYRTGDLVRYLPDGQIDFVGRADHRVKISGYRIELGEVEAA 955 Query 964 LQRLPGVHAAAATVLP----GGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVT 1019 L+R+ V AA A VL G + LAA V VT + + +++A+LVP HM+P H+ Sbjct 956 LRRIAVVEAAVAAVLTAPGDGRGEQLAAIVRASSPAVTVDELTRRMAELVPPHMVPSHIA 1015 Query 1020 LLDRIPFTDSGKIDRAEVGALLAAEV-ERSGDRSAPYAAPRTVLQRALRRIVADILGRAN 1078 L++ +PFT GKIDR V A L + ER+ ++ Y AP T L+RAL IVA +L R Sbjct 1016 LVEAVPFTVGGKIDRRAVTAELTRSMAERANAQAPTYRAPSTALERALADIVATVLDR-- 1073 Query 1079 DAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANA 1138 D+VG DDFF LGGDSVLATQ VA IR WLDSP +MV D+FAAR + ALA+ L E+ + Sbjct 1074 DSVGADDDFFELGGDSVLATQAVARIREWLDSPGVMVTDIFAARRVGALARRLVDHESGS 1133 Query 1139 DRLELVAEVYLEIANMTSADVMAAL 1163 DRLE VAE+YLE+A+M SADV +AL Sbjct 1134 DRLEGVAELYLEVADMNSADVASAL 1158 >gi|108800436|ref|YP_640633.1| amino acid adenylation [Mycobacterium sp. MCS] gi|119869565|ref|YP_939517.1| amino acid adenylation domain-containing protein [Mycobacterium sp. KMS] gi|118572774|sp|Q1B6A7.1|MBTB_MYCSS RecName: Full=Phenyloxazoline synthase MbtB; AltName: Full=Mycobactin synthetase protein B gi|108770855|gb|ABG09577.1| Amino acid adenylation [Mycobacterium sp. MCS] gi|119695654|gb|ABL92727.1| amino acid adenylation domain [Mycobacterium sp. KMS] Length=1167 Score = 1288 bits (3332), Expect = 0.0, Method: Compositional matrix adjust. Identities = 715/1165 (62%), Positives = 843/1165 (73%), Gaps = 21/1165 (1%) Query 7 CSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPT 66 S+ +RAEVAELLG+ AL P A+L+ GLDSIRMMSL GRWR++GI V FA +AA PT Sbjct 7 SSQTVRAEVAELLGIEESALDPDADLIASGLDSIRMMSLSGRWRKQGIDVRFAAMAANPT 66 Query 67 IEAWSQLVSAGTGVAPTAVAAPGDAGLS--QEGEPFPLAPMQHAMWVGRHDHQQLGGVAG 124 + AW++LV T +P A GD S PFPLAP+QHA+WVGR++ +LGGVA Sbjct 67 VAAWTRLVGERTAESPGAATQSGDTAASAGDPDAPFPLAPIQHALWVGRNELTELGGVAA 126 Query 125 HLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRH 184 HLYVEFDGA VDP+RLR AA LA RHPMLRV L DG QRI RD P+ V DLRH Sbjct 127 HLYVEFDGAGVDPERLRTAAAALAARHPMLRVDILGDGMQRI----SDRDLPVKVTDLRH 182 Query 185 VAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLA 244 + +Q+L IR AKSHQ L+G V ELALTLLP RTRLHVDLDMQAADA+SYR +A Sbjct 183 LDVADAEQQLEVIRHAKSHQLLEGEVLELALTLLPDGRTRLHVDLDMQAADAVSYRNFMA 242 Query 245 DLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRA 304 DLAALY G + P L YTYR+YR A A P P D DR WW +RIP LP+PPALP Sbjct 243 DLAALYRGAQLPELQYTYRQYRSAFTAT---PAPTVDEDRRWWTERIPDLPEPPALPLVP 299 Query 305 GGE-RDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLN 363 E RD RR TRRWH+LD RD LFA ARARGITPAM AA++A LARWS S FLLN Sbjct 300 RAEQRDPRRGTRRWHFLDTDIRDRLFAAARARGITPAMAFAASYAGTLARWSTSRHFLLN 359 Query 364 LPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLS 423 LP+F R+ HPDVD LVGDFTSSL+LDVD T A T A RA+ +QEAL ++A H+ Y GLS Sbjct 360 LPMFGREPFHPDVDKLVGDFTSSLMLDVDFTEAHTPAQRARVMQEALHTSAEHATYSGLS 419 Query 424 VLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFD 483 VLRDLSRH G+ LAP VFTSALGLGDLF DVT+QFGTP W ISQGPQVLLDAQVT FD Sbjct 420 VLRDLSRHHGSPSLAPFVFTSALGLGDLFAGDVTDQFGTPVWHISQGPQVLLDAQVTPFD 479 Query 484 GGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALN 543 GG+LVNWDVRE F PGVIDAMF +Q+ EL RLAA D AWDA P A+P AQRAVR A+N Sbjct 480 GGLLVNWDVREDAFRPGVIDAMFAYQLAELERLAADDAAWDAADPPAVPPAQRAVRDAVN 539 Query 544 GRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRVGD 603 A S +ALHDGFFR A PDA AV S+G L+YA+LR++ AV AL+ AG++ GD Sbjct 540 DTGARRSDDALHDGFFRTAAHTPDATAVIGSTGTLTYAELRERVLAVTGALQVAGIKPGD 599 Query 604 TVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVR 663 TVAV+GPK +QV A+L I AAG VY+PIG DQP DRA+ IL T V +AL CG Sbjct 600 TVAVMGPKCADQVTALLAIHAAGAVYVPIGADQPADRADSILQTAGVRMALACGDEPPTF 659 Query 664 VPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVETFI 723 +P T+ A + + P +P +AYVLFTSGSTG PKGVEV H AAMNT+E Sbjct 660 LPALTIAEAVRVGSRVHGVTPATVEPDRVAYVLFTSGSTGAPKGVEVTHAAAMNTLEFIN 719 Query 724 RHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVT 783 HF +G +DR LAL+TLE D+SVLD+F LR+GG++VVVDEAQRRDPD+WARLI + VT Sbjct 720 DHFGIGPSDRSLALSTLEGDLSVLDVFGMLRAGGSLVVVDEAQRRDPDSWARLIAEHSVT 779 Query 784 ALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETA 843 L++MPGWL+MLLEVGG L S+R V GGDWVR ++ R L+ AP RFAGLGGATETA Sbjct 780 VLHWMPGWLEMLLEVGGA-LPSVRVVPTGGDWVRTEMVRELRRAAPGVRFAGLGGATETA 838 Query 844 VHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARG 903 +H TI E LP +W++VP+G P PNNACRVVA G DCPDWV GELWV GRGIARG Sbjct 839 IHNTICE---PGELPREWSAVPFGRPLPNNACRVVAADGADCPDWVPGELWVGGRGIARG 895 Query 904 YRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAA 963 YRGRP+LTAERFV HDGRTWYRTGDL RY DG ++FVGRADHRVKISGYR+ELGE+EAA Sbjct 896 YRGRPDLTAERFVVHDGRTWYRTGDLVRYLPDGQIDFVGRADHRVKISGYRIELGEVEAA 955 Query 964 LQRLPGVHAAAATVLP----GGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVT 1019 L+R+ GV AA A VL G + LAA V VT + + +++A+LVP HM+P H+ Sbjct 956 LRRIAGVEAAVAAVLTAPGDGRGEQLAAIVRASSPAVTVDELTRRMAELVPPHMVPSHIA 1015 Query 1020 LLDRIPFTDSGKIDRAEVGALLAAEV-ERSGDRSAPYAAPRTVLQRALRRIVADILGRAN 1078 L++ +PFT GKIDR V A L + ER+ ++ Y P T L+RAL IV+ +L R Sbjct 1016 LVEAVPFTVGGKIDRRAVTAELTRSMAERANAQAPTYRVPSTALERALADIVSTVLDR-- 1073 Query 1079 DAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANA 1138 D+VG DDFF LGGDSVLATQ VA IR WLDSP +MV D+FAAR + ALA+ L E+ + Sbjct 1074 DSVGADDDFFELGGDSVLATQAVARIREWLDSPGVMVTDIFAARRVGALARRLVDHESGS 1133 Query 1139 DRLELVAEVYLEIANMTSADVMAAL 1163 DRLE VAE+YLE+A+M SADV +AL Sbjct 1134 DRLEGVAELYLEVADMNSADVASAL 1158 >gi|120404807|ref|YP_954636.1| amino acid adenylation domain-containing protein [Mycobacterium vanbaalenii PYR-1] gi|119957625|gb|ABM14630.1| amino acid adenylation domain [Mycobacterium vanbaalenii PYR-1] Length=1149 Score = 1246 bits (3225), Expect = 0.0, Method: Compositional matrix adjust. Identities = 687/1169 (59%), Positives = 828/1169 (71%), Gaps = 34/1169 (2%) Query 4 ATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAA 63 A+ + +R EVAELLGV L P A+L+ GLDSIRMM+L GRWRR+G+ V FA LAA Sbjct 4 ASTTAMSVRDEVAELLGVSPAELDPQADLIASGLDSIRMMTLSGRWRRQGVDVGFAALAA 63 Query 64 TPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVA 123 PT+ AW++LVS A G EG+ FPLAP+QHAMW+GR++ QQLGGVA Sbjct 64 NPTVAAWTELVSGRDAPPAADPAPDATTG-PGEGDTFPLAPIQHAMWIGRNEDQQLGGVA 122 Query 124 GHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLR 183 HLYVEFDGA VDPDRLR AA +LA RHPMLRV+ LPDGTQRI G R P++V DLR Sbjct 123 AHLYVEFDGAGVDPDRLRDAAAKLAARHPMLRVEILPDGTQRI----GDRGLPVTVYDLR 178 Query 184 HVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILL 243 + +RL GIRD KSHQ + G V +++L+LL RTRLHVD+DMQAADA+SYR + Sbjct 179 DLDLLAAAERLEGIRDEKSHQMMHGEVLQISLSLLADGRTRLHVDMDMQAADAVSYRNFM 238 Query 244 ADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTR 303 ADLA Y G P LGYTYREYR A+ + D DR WWA+R+P LP+ PALP Sbjct 239 ADLADFYSGVTLPELGYTYREYRAALTSTTV----ESDEDRRWWAERVPGLPEGPALPLV 294 Query 304 AGGER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLL 362 E+ D +R+ RRWH D TRDALFA A RGITPAM +AA++A LARWS + RFLL Sbjct 295 PRSEQADPKRARRRWHIFDVATRDALFAAAHRRGITPAMAVAASYAGTLARWSTNRRFLL 354 Query 363 NLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGL 422 NLP+F R+ HPDVD LVGDFTSSL+LDVDL+GA T AR + +QE L + A HS+Y GL Sbjct 355 NLPMFGREQFHPDVDKLVGDFTSSLMLDVDLSGADTPMARCRVLQETLHTTAQHSSYSGL 414 Query 423 SVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEF 482 SVLRDL+RH GT LAPVV+TSALGLGDLF VTE FG P W ISQGPQVLLDAQ T Sbjct 415 SVLRDLTRHHGTPTLAPVVYTSALGLGDLFAGKVTEHFGRPVWTISQGPQVLLDAQATPV 474 Query 483 DGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAAL 542 G+++NWD RE F PGV DAMF + + EL RLA + AWDA PSA+ A Q+A R + Sbjct 475 AEGLMINWDTREDAFRPGVADAMFAYHLAELERLATDESAWDAADPSAVTAQQQAARDVV 534 Query 543 NGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRVG 602 N T PS + LH GFFR A+ PDAPAV+ GDL+Y +LR+Q AVAAAL AG+R Sbjct 535 NAVTRTPSGDVLHAGFFRNAEAYPDAPAVWCRDGDLTYGELREQVLAVAAALHVAGVRRA 594 Query 603 DTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCG--PPC 660 DTVAV+GPK EQ+ A+L I A G Y+P+GVD P +RA R+LA G+V +ALVCG PP Sbjct 595 DTVAVMGPKNFEQIVALLAISAIGAAYVPVGVDHPAERAARMLANGAVRMALVCGDRPPT 654 Query 661 QVRVPVPTLLLADVLAAA--PAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNT 718 + P L +A+ L EF DP LAY+LFTSGSTGEPKGVE++HDAAMNT Sbjct 655 TL----PALTVAEALRVGRRETEFTLPAVDPADLAYILFTSGSTGEPKGVEMSHDAAMNT 710 Query 719 VETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLID 778 VE HF++G ADR LAL+TLECD+SVLD+F L +GG+IVVVDE RRDPD WARL++ Sbjct 711 VEFINAHFDIGPADRCLALSTLECDLSVLDVFGMLGAGGSIVVVDEEHRRDPDVWARLVE 770 Query 779 TYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGG 838 + VT L+FMPGWL+ML EV G LSSLR V GGDWVRP++ R L+ +AP RFAGLGG Sbjct 771 RHGVTVLHFMPGWLEMLAEVDGD-LSSLRVVPTGGDWVRPEMVRALRKRAPHMRFAGLGG 829 Query 839 ATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGR 898 ATETA H TI EV+D +P +W SVP GVP PNN CRVV G DCPDWV GELWV GR Sbjct 830 ATETATHNTICEVED---IPAEWTSVPLGVPLPNNTCRVVGPDGRDCPDWVPGELWVGGR 886 Query 899 GIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELG 958 G+ARGY RP+LTAERFVE+DGRTWYRTGDL RY G +EFVGRADHR+KISGYRVELG Sbjct 887 GVARGYCARPDLTAERFVEYDGRTWYRTGDLVRYRPGGVIEFVGRADHRIKISGYRVELG 946 Query 959 EIEAALQRLPGVHAAAATVLP--GGSDVLAAAVCVDDAGVT-AESIRQQLADLVPAHMIP 1015 E+E+AL+R+PGV +A A V+ GG DVLAA + +GV + + +A++VP HMIP Sbjct 947 EVESALRRIPGVDSAVAAVVAADGGRDVLAALI----SGVADPQKVTTAMAEVVPPHMIP 1002 Query 1016 RHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILG 1075 + + D IP+T GKIDRA V +LA + G Y AP T L+ AL I+ +LG Sbjct 1003 QIIVAADHIPYTLGGKIDRAAVTRMLADADLQCG---TGYRAPATPLESALCDIIGTVLG 1059 Query 1076 RANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGRE 1135 RA AVG DDFFA GGDSVLATQVVA +R WLD+P++ VAD+FA RT AALA L+ E Sbjct 1060 RA--AVGADDDFFASGGDSVLATQVVARVRTWLDTPAVAVADIFATRTAAALAARLSAGE 1117 Query 1136 ANADRLELVAEVYLEIANMTSADVMAALD 1164 RL VAE+YL++A M A+V++AL+ Sbjct 1118 PEGTRLAEVAELYLQVAGMDGAEVVSALE 1146 >gi|145223279|ref|YP_001133957.1| amino acid adenylation domain-containing protein [Mycobacterium gilvum PYR-GCK] gi|145215765|gb|ABP45169.1| amino acid adenylation domain [Mycobacterium gilvum PYR-GCK] Length=1152 Score = 1216 bits (3146), Expect = 0.0, Method: Compositional matrix adjust. Identities = 675/1170 (58%), Positives = 814/1170 (70%), Gaps = 33/1170 (2%) Query 4 ATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAA 63 A+ + +R EVAELLG+ L P A+L+ GLDSIRMMSL GRWRR+GI V FA LAA Sbjct 2 ASTTAPSVRDEVAELLGIDPGGLDPEADLIASGLDSIRMMSLSGRWRRQGIDVGFAALAA 61 Query 64 TPTIEAWSQLVSAGTGVAPTAV---AAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 PT+ AW++LV+ + AP V AAP G + FPLAP+QHAMWVGR+D QQLG Sbjct 62 NPTVAAWTELVADRS--APPIVDETAAPNVHG-DDVSDTFPLAPIQHAMWVGRNDDQQLG 118 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GV HLYVEFDGA VDP RLR AA RLA RHPMLRV+ LPDG QRI R P++V Sbjct 119 GVGAHLYVEFDGAGVDPVRLREAAGRLAQRHPMLRVEILPDGMQRI----SDRGLPVTVY 174 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLR + + RL IR KSHQ L G V +L+L+LL RTR+HVD+DMQA+DA+SYR Sbjct 175 DLRDLDAATAEHRLDEIRHEKSHQMLHGEVLQLSLSLLADGRTRVHVDMDMQASDAVSYR 234 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 +ADLA Y G + P LGYTYREYR AE D DR WWA+RIP+LP+ P L Sbjct 235 NFMADLAEFYSGADLPELGYTYREYR----AELAATTAESDEDRRWWAERIPELPEGPTL 290 Query 301 PTRAGGER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSR 359 P E+ D +RS RRWH LD RDALFA A+ RGITPAM +AA++A LARWS R Sbjct 291 PLVPRAEQQDPKRSRRRWHILDVAARDALFAAAQRRGITPAMAVAASYAGTLARWSTQRR 350 Query 360 FLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAY 419 FLLNLP+F R+ HPDVD LVGDFTSSL+LDVDLTGA T AR + +QE L + A H+ Y Sbjct 351 FLLNLPMFGREQFHPDVDKLVGDFTSSLMLDVDLTGADTPLARCRVLQETLHATARHAGY 410 Query 420 PGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQV 479 GLSVLRDL+RH GT VLAP+V+TSA+GLGDLF VTE FG P W ISQGPQVLLDAQ Sbjct 411 SGLSVLRDLTRHHGTPVLAPIVYTSAIGLGDLFAGKVTEHFGRPVWTISQGPQVLLDAQA 470 Query 480 TEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVR 539 T G+++NWD RE F PGV DAMF H + EL RLA + AWD P+A+PA Q+A R Sbjct 471 TPVAEGLMINWDTREDAFRPGVADAMFAHHIAELERLATDESAWDTIDPTAVPADQQAAR 530 Query 540 AALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGL 599 A+N A S + LHDGFFR+AQ +PDAPAV++ G L+Y +LR VAAAL+ AG+ Sbjct 531 DAVNTVADAASGDTLHDGFFRRAQARPDAPAVWSHDGALTYGELRATVLDVAAALQVAGI 590 Query 600 RVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPP 659 R GD VAV+GPK EQV A+L I A G VY+P+GV+ P +RA R+LA G V +ALVCG Sbjct 591 RHGDAVAVMGPKNHEQVIALLAISALGAVYVPVGVEHPAERATRMLANGRVRMALVCGDE 650 Query 660 CQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTV 719 + T+ A + F +PT LAY+LFTSGSTGEPKGVE+ H A+MNTV Sbjct 651 PVTTMCSLTVQEAIRVGRRATGFTLPAVEPTDLAYILFTSGSTGEPKGVEMTHAASMNTV 710 Query 720 ETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDT 779 E HFE+G DR LAL+TLECD+SVLD+F LR+GG+IVVVDE RRD + WA LI+ Sbjct 711 EFINGHFEIGPDDRCLALSTLECDLSVLDVFGMLRAGGSIVVVDEEHRRDAEVWAHLIEQ 770 Query 780 YEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGA 839 + VT L+FMPGWL+ML EVGG LSS+R V GGDWVRPD+ R L+ +AP RFAGLGGA Sbjct 771 HGVTVLHFMPGWLEMLTEVGGD-LSSVRVVPTGGDWVRPDMVRALRKRAPGMRFAGLGGA 829 Query 840 TETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRG 899 TETA H TI E+ ++P +W S+P GVP PNNACRVV G DCPDWV GELWV GRG Sbjct 830 TETATHNTICEI--VGDIPQEWTSIPLGVPLPNNACRVVGPDGRDCPDWVPGELWVGGRG 887 Query 900 IARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGE 959 IARGY RP+LTAERFV + + WYRTGDL RY G +EFVGR DHRVKISGYRVELGE Sbjct 888 IARGYCARPDLTAERFVRYQDQNWYRTGDLVRYRTGGVIEFVGRVDHRVKISGYRVELGE 947 Query 960 IEAALQRLPGVHAAAATVLP--GGSDVLAAAV-CVDDAGVTAESIRQQLADLVPAHMIPR 1016 +E+AL+R+PGV +A A ++P GG DVLAA + V A V A + + LV HMIP+ Sbjct 948 VESALRRIPGVESAVAAMVPADGGRDVLAALIEPVAGAAVDAAGVIAAMGQLVAPHMIPK 1007 Query 1017 HVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGR 1076 V RIPFT GKIDR V LL + +S + AP T L+ AL ADILG Sbjct 1008 IVEPAPRIPFTAGGKIDRQAVAKLLG---QARSPQSRAHRAPVTSLECAL----ADILGG 1060 Query 1077 AND--AVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGR 1134 D A+G DDFFA GGDSVLATQ V+ IR WLD+ ++ VAD+F ART++ALA+ LT R Sbjct 1061 VLDGVALGADDDFFACGGDSVLATQAVSRIRTWLDTSTVAVADIFGARTVSALAERLTAR 1120 Query 1135 EANADRLELVAEVYLEIANMTSADVMAALD 1164 + +RLE VAE+YL++A M +ADV++ L+ Sbjct 1121 D---ERLEKVAEMYLDVARMDAADVVSTLE 1147 >gi|315443739|ref|YP_004076618.1| amino acid adenylation enzyme/thioester reductase family protein [Mycobacterium sp. Spyr1] gi|315262042|gb|ADT98783.1| amino acid adenylation enzyme/thioester reductase family protein [Mycobacterium sp. Spyr1] Length=1154 Score = 1214 bits (3142), Expect = 0.0, Method: Compositional matrix adjust. Identities = 671/1169 (58%), Positives = 809/1169 (70%), Gaps = 31/1169 (2%) Query 4 ATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAA 63 A+ + +R EVAELLG+ L P A+L+ GLDSIRMMSL GRWRR+GI V FA LAA Sbjct 4 ASTTAPSVRDEVAELLGIDPGGLDPEADLIASGLDSIRMMSLSGRWRRQGIDVGFAALAA 63 Query 64 TPTIEAWSQLVSAGTGVAPTA--VAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGG 121 PT+ AW++LV A P AAP G + FPLAP+QHAMWVGR+D QQLGG Sbjct 64 NPTVAAWTELV-ADRSTPPIVDETAAPSVHG-DDVSDTFPLAPIQHAMWVGRNDDQQLGG 121 Query 122 VAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVAD 181 V HLYVEFDGA VDP RLR AA RLA RHPMLRV+ LPDG QRI R P++V D Sbjct 122 VGAHLYVEFDGAGVDPVRLREAAGRLAQRHPMLRVEILPDGMQRI----SDRGLPVTVYD 177 Query 182 LRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYRI 241 LR + + RL IR KSHQ L G V +L+L+LL RTR+HVD+DMQA+DA+SYR Sbjct 178 LRDLDAATAEHRLDEIRHEKSHQMLHGEVLQLSLSLLADGRTRVHVDMDMQASDAVSYRN 237 Query 242 LLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALP 301 +ADLA Y G + P LGYTYREYR AE D DR WWA+RIP+LP+ P LP Sbjct 238 FMADLAEFYSGADLPELGYTYREYR----AELAATTAESDEDRRWWAERIPELPEGPTLP 293 Query 302 TRAGGER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 E+ D +RS RRWH LD RDALFA A+ RGITPAM +AA++A LARWS RF Sbjct 294 LVPRAEQQDPKRSRRRWHVLDVAARDALFAAAQRRGITPAMAVAASYAGTLARWSTQRRF 353 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLP+F R+ HPDVD LVGDFTSSL+LDVDLTGA T AR + +QE L + A H+ Y Sbjct 354 LLNLPMFGREQFHPDVDKLVGDFTSSLMLDVDLTGADTPLARCRVLQETLHATARHAGYS 413 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDL+RH GT VLAP+V+TSA+GLGDLF VTE FG P W ISQGPQVLLDAQ T Sbjct 414 GLSVLRDLTRHHGTPVLAPIVYTSAIGLGDLFAGKVTEHFGRPVWTISQGPQVLLDAQAT 473 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRA 540 G+++NWD RE F PGV DAMF H + EL RLA + AW+ P+A+PA Q+A R Sbjct 474 PVAEGLMINWDTREDAFRPGVADAMFAHHIAELERLATDESAWETIDPTAVPADQQAARD 533 Query 541 ALNGRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLR 600 A+N A S + LHDGFFR+AQ +PDAPAV++ G L+Y +LR VAAAL+ AG+R Sbjct 534 AVNTVADAASGDTLHDGFFRRAQARPDAPAVWSHDGALTYGELRATVLDVAAALQVAGIR 593 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 GD VAV+GPK EQV A+L I A G VY+P+GV+ P +RA R+LA G V +ALVCG Sbjct 594 HGDAVAVMGPKNHEQVIALLAISALGAVYVPVGVEHPAERATRMLANGRVRMALVCGDEP 653 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 + T+ A + F +PT LAY+LFTSGSTGEPKGVE+ H A+MNTVE Sbjct 654 VTTMCSLTVQEAIRVGRRATGFTLPAVEPTDLAYILFTSGSTGEPKGVEMTHAASMNTVE 713 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 HFE+G DR LAL+TLECD+SVLD+F LR+GG+IVVVDE RRD + WARLI+ + Sbjct 714 FINGHFEIGPDDRCLALSTLECDLSVLDVFGMLRAGGSIVVVDEEHRRDAEVWARLIEQH 773 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 VT L+FMPGWL+ML EVGG LSS+R V GGDWVRPD+ R L+ +AP RFAGLGGAT Sbjct 774 GVTVLHFMPGWLEMLTEVGGD-LSSVRVVPTGGDWVRPDMVRALRKRAPGMRFAGLGGAT 832 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETA H TI E+ ++P +W S+P GVP PNNACRVV G DCPDWV GELWV GRGI Sbjct 833 ETATHNTICEI--VGDIPQEWTSIPLGVPLPNNACRVVGPDGRDCPDWVPGELWVGGRGI 890 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 ARGY RP+LTAERFV + + WYRTGDL RY G +EFVGR DHRVKISGYRVELGE+ Sbjct 891 ARGYCARPDLTAERFVRYQDQNWYRTGDLVRYRTGGVIEFVGRVDHRVKISGYRVELGEV 950 Query 961 EAALQRLPGVHAAAATVLP--GGSDVLAAAV-CVDDAGVTAESIRQQLADLVPAHMIPRH 1017 E+AL+R+PGV +A A ++P GG +VLAA V V A V A + + LV HMIP+ Sbjct 951 ESALRRIPGVESAVAAMVPADGGREVLAALVEPVAGAAVDAAGVIAAMGQLVAPHMIPKI 1010 Query 1018 VTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRA 1077 V RIPFT GKIDR V LL G +P + L +L +ADILG Sbjct 1011 VEPAPRIPFTAGGKIDRQAVAKLL-------GQARSPQSRAHRALVTSLECALADILGGV 1063 Query 1078 ND--AVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGRE 1135 D A+G DDFFA GGDSVLATQ V+ IR WLD+ ++ VAD+F ART++ALA+ LT R+ Sbjct 1064 LDGVALGADDDFFACGGDSVLATQAVSRIRTWLDTSTVAVADIFGARTVSALAERLTARD 1123 Query 1136 ANADRLELVAEVYLEIANMTSADVMAALD 1164 +RLE VAE+YL++A M +ADV++ L+ Sbjct 1124 ---ERLEKVAEMYLDVARMDAADVVSTLE 1149 >gi|54022735|ref|YP_116977.1| putative non-ribosomal peptide synthetase [Nocardia farcinica IFM 10152] gi|54014243|dbj|BAD55613.1| putative non-ribosomal peptide synthetase [Nocardia farcinica IFM 10152] Length=1167 Score = 1085 bits (2807), Expect = 0.0, Method: Compositional matrix adjust. Identities = 609/1166 (53%), Positives = 759/1166 (66%), Gaps = 31/1166 (2%) Query 11 IRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAW 70 +RA +A LG+ + + G +L+ GLDSIR M L G WR++G+ V+FA LAA PT+EAW Sbjct 20 VRAAIAAQLGLAVEDIADGDDLIQLGLDSIRTMKLAGGWRKRGVDVNFAQLAAEPTVEAW 79 Query 71 SQLVSAGTGVAPTAVAAPGDAGLSQ---EGEPFPLAPMQHAMWVGRHDHQQLGGVAGHLY 127 L+ AG G P A P + E PFPLA MQHA W+GR Q+LGGVA HLY Sbjct 80 YALLGAGDGAEPVAAEEPAGQQAAADADESAPFPLATMQHAYWIGRSGEQELGGVAAHLY 139 Query 128 VEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAP 187 VEFDG R+DP RL A L HPMLR +FLPDGTQ+ PA G F SV DLR Sbjct 140 VEFDGGRIDPARLEKAVADLVAAHPMLRTRFLPDGTQQTMPAPGKPVF--SVVDLRDRDA 197 Query 188 DVVDQRLAGIRDAKSHQQLD---GAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLA 244 D + LA +R+ K+HQ LD G V ++ LTL TRLH+D+DM A DAMSYR+L++ Sbjct 198 DATEAALADLREQKTHQLLDIEAGQVIDITLTLRDENSTRLHLDVDMLAGDAMSYRVLIS 257 Query 245 DLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRA 304 DLA LY G P GY+YR YR E + + R+ DR WW +R+P+LP P LPT Sbjct 258 DLADLYHGATLPTPGYSYRRYR----TERQIDEAARERDRRWWQERLPELPGAPELPTVP 313 Query 305 GGER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLN 363 ER D R+ R HWL P+ + L A A RGITPAM LAA FA V+ WSA SRFLLN Sbjct 314 VAERTDPHRTVRYNHWLAPEAKQRLLAAAHERGITPAMALAAVFAEVIGGWSAQSRFLLN 373 Query 364 LPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLS 423 +PLF R+ +HPD+D ++GDFTSS++L+VD+T T A RA+A+Q ++ + H+AY GL Sbjct 374 VPLFHREPVHPDIDRVIGDFTSSIMLEVDVTENMTVADRARALQRSMHDSGAHTAYSGLE 433 Query 424 VLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFD 483 VLRDL RHRG VLAPVV+TSAL LG+LF VTE FG P WIISQGPQVLLDAQVTE Sbjct 434 VLRDLGRHRGEPVLAPVVYTSALNLGELFADKVTETFGEPVWIISQGPQVLLDAQVTEVR 493 Query 484 GGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALN 543 GG+L+NWDVRE F G+I+AMF + + RL G+ W A + LP AQ VRAA+N Sbjct 494 GGLLLNWDVRESAFPDGMIEAMFACYTEAIGRLGEGEAGWQAEAAVRLPRAQAEVRAAVN 553 Query 544 GRTAAPSTEALHDGFFRQAQQQPDAPAVF----ASSGDLSYAQLRDQASAVAAALRAAGL 599 S LH+GFF +A PDA AV A G +Y +L QA AVA ALRA G+ Sbjct 554 ATDGPVSGRCLHEGFFTRAAANPDATAVVWGIGADEGRWTYGELAGQALAVAGALRAEGV 613 Query 600 RVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPP 659 GD VAV PK +Q+ AVLG+LAAG Y+PIG DQP R IL TG + AL P Sbjct 614 GRGDAVAVQLPKGRDQILAVLGVLAAGATYVPIGFDQPVGRRAEILRTGDIVAALTV-PG 672 Query 660 CQVRVPVPTLLLADVLAAAPAEFVPGPSDPTA-LAYVLFTSGSTGEPKGVEVAHDAAMNT 718 + VP+PTL + D A PA PT+ +AYV+FTSGSTG PKGV+V H AMNT Sbjct 673 ADLGVPIPTLSI-DAARAYPAPLDAPDIPPTSEIAYVIFTSGSTGVPKGVDVPHSGAMNT 731 Query 719 VETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLID 778 ++ FE+G+ADR LAL+ LE D SV DIF GG+IV VD +R + W L+ Sbjct 732 IDAVNDWFEVGSADRVLALSALEFDASVYDIFGMFAVGGSIVAVDAERRAEATTWVDLLR 791 Query 779 TYEVTALNFMPGWLDMLLEVGGGRLS-SLRAVAVGGDWVRPDLARRLQVQAPSARFAGLG 837 + VT LN +P LDM+LE+GG L SLRAV +GGDWV DLARRL Q P RF+GLG Sbjct 792 HHRVTILNCVPSMLDMILEIGGDELGDSLRAVTLGGDWVGADLARRLARQVPGCRFSGLG 851 Query 838 GATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSG 897 GATET++H TI EV P WA+VP+GVP N CRVV+ +G DCPDWV GE WV G Sbjct 852 GATETSIHNTICEV--VGEPPAHWATVPFGVPLRNVRCRVVSQAGRDCPDWVPGEFWVGG 909 Query 898 RGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVEL 957 +A GYR PE TAERFVEHDG WY+TGD+ARYW DGT+EF+GRADH+V+I GYRVEL Sbjct 910 ANVAAGYRNDPERTAERFVEHDGMRWYKTGDMARYWPDGTIEFLGRADHQVQIRGYRVEL 969 Query 958 GEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRH 1017 GE+E+AL+ +PGV A A V+ G+ L AAV + + I +A L+PA+MIP Sbjct 970 GEVESALRTVPGVRHAVAAVVGAGAPKLVAAVAGERGEIG--DITGAVAHLLPAYMIPTR 1027 Query 1018 VTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRA 1077 + LD++P T +GK+DR V ALL V D +PR ++ AL IVA +LG Sbjct 1028 IEYLDQMPLTANGKLDRRAVVALLEPRV----DGEDVDGSPRDDVEAALADIVAGVLG-- 1081 Query 1078 NDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREAN 1137 ++VGVHDDFF +GGDSVLAT V+A IR WLD +VAD+FA+RTIAALA L RE++ Sbjct 1082 VESVGVHDDFFGMGGDSVLATTVIARIREWLDLDHALVADLFASRTIAALATRLAERESD 1141 Query 1138 ADRLELVAEVYLEIANMTSADVMAAL 1163 +RL VA +YLE++ MT +++A + Sbjct 1142 PNRLTEVARMYLEVSAMTDEEILAQM 1167 >gi|296394827|ref|YP_003659711.1| amino acid adenylation domain-containing protein [Segniliparus rotundus DSM 44985] gi|296181974|gb|ADG98880.1| amino acid adenylation domain protein [Segniliparus rotundus DSM 44985] Length=1164 Score = 1040 bits (2690), Expect = 0.0, Method: Compositional matrix adjust. Identities = 595/1166 (52%), Positives = 753/1166 (65%), Gaps = 33/1166 (2%) Query 9 EIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIE 68 E IR +VA +L V D+L A+L+ GLDSIRMMSL G WR++G+ V F LAA PT+ Sbjct 9 EKIRHQVAGVLAVPPDSLATDADLISLGLDSIRMMSLAGAWRKQGVDVAFGALAAAPTLA 68 Query 69 AWSQLVSAGTGVAPTAV---AAPGDAG-LSQEGEPFPLAPMQHAMWVGRHDHQQLGGVAG 124 W L+ AV AAP AG L+ G+ FPLA MQHA WVGR Q+LGGVA Sbjct 69 GWHALLQNAPKKPSPAVRSSAAPVQAGELASAGKVFPLAAMQHAQWVGRDGGQRLGGVAA 128 Query 125 HLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRH 184 HLYVEFDGA VDP RL+AA L RHPMLRVQ LP+G QR+ PAAG + F + DL Sbjct 129 HLYVEFDGAHVDPARLKAAVDLLVQRHPMLRVQILPEGAQRVLPAAGGQVF--AHEDLGA 186 Query 185 VAPDVVDQRLAGIRDAKSHQQL---DGAVFELALTLLPGERTRLHVDLDMQAADAMSYRI 241 +A +RL IR+ KSHQ L +G VF++ L LP R+RL +D+DM AADAMSYR+ Sbjct 187 LAEHDAQERLELIREQKSHQHLAVHEGQVFDVLLVSLPDGRSRLCLDVDMIAADAMSYRV 246 Query 242 LLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALP 301 L+ADLAALY G L T++E+ +E + + + DR WWA+R+ LP PP LP Sbjct 247 LVADLAALYRGERLEPLSITFQEH---LERKRAVADSREETDRAWWAERLAALPPPPELP 303 Query 302 TRAGGER---DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASS 358 E R+TRR +WL PQ + ALF R R+RG+TPAM LA+ FA + WSA+ Sbjct 304 VLPEAESGLAHSPRATRRHYWLSPQRKQALFERCRSRGVTPAMALASIFATAIGNWSANP 363 Query 359 RFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSA 418 +FLLNLPLF+R A +D +VGDFTSS++L VDL +T RA ++Q++ AA HSA Sbjct 364 KFLLNLPLFTRDAADSRLDRVVGDFTSSVMLSVDLAEPQTVGERACSLQQSFHEAAAHSA 423 Query 419 YPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQ 478 Y GL+VLRDLSR G Q+LAPVV+TSA+GLG+LF V E FG P ++SQGPQV LDAQ Sbjct 424 YSGLNVLRDLSRLHGEQILAPVVYTSAIGLGELFAQGVAETFGKPVHVLSQGPQVALDAQ 483 Query 479 VTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPS-PSALPAAQRA 537 VTE DGG+L+NWDVRE + PGV++AMF E+ RLA + W A S ALPA QR Sbjct 484 VTEIDGGLLLNWDVREPLLRPGVVEAMFAWYTAEIERLATDPEQWAALSGQGALPARQRE 543 Query 538 VRAALNGRTAAPSTE-ALHDGFFRQAQQQPDAPAVFASSGDL-SYAQLRDQASAVAAALR 595 VR AL A T+ ALH GFF A++ P A AV A G + +YA+LR QA AVA AL Sbjct 544 VREALRASAPASDTQRALHTGFFENAERNPGAVAVIAEDGSVTTYAELRRQALAVAGALA 603 Query 596 AAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALV 655 G+R G+ VAV K Q+ +LG+LA+GGVY+P+GVDQP+ R ++I T + + Sbjct 604 ELGVRRGEAVAVALAKGAAQIPVLLGVLASGGVYVPVGVDQPQARRQQIARTARIAAVIA 663 Query 656 CGPPCQVRVPVPTLLLADVLAAAPAEF---VPGPSDPTA--LAYVLFTSGSTGEPKGVEV 710 V + V A + E +P P TA LAYVLFTSGSTGEPKGVE+ Sbjct 664 PDDVAAASVEAWAGTVPAVSATSATEHPRPLPEPVAVTADDLAYVLFTSGSTGEPKGVEL 723 Query 711 AHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDP 770 H A MNT+ + F + DR L+L+ LECD SV DIF GG++VV++EA R++P Sbjct 724 RHGAPMNTIAAVVDRFGITETDRCLSLSPLECDWSVFDIFGMFSVGGSVVVIEEASRQEP 783 Query 771 DAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPS 830 WA+L+ T+EVT + +MPGWLD+LL+ G L SLR GGDWV DL RRL+V+AP Sbjct 784 ALWAQLMRTHEVTYIGWMPGWLDLLLDASSGDLPSLRVALAGGDWVSADLPRRLRVRAPQ 843 Query 831 ARFAGLGGATETAVHATIFEVQDAANLPP-DWASVPYGVPFPNNACRVVADSGDDCPDWV 889 RFAGLGGATETA+H+T+FEV + PP W ++P+G P CRVV G+DCPDWV Sbjct 844 TRFAGLGGATETAIHSTVFEVPNEEGSPPAHWRAIPFGRPLAGVRCRVVNPRGEDCPDWV 903 Query 890 AGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVK 949 GE WV G GIA GYRG PE T +RFV++ G WYRTGDL R W DG LEFVGR DHR+K Sbjct 904 PGEYWVGGAGIAEGYRGDPERTEQRFVQYQGERWYRTGDLVRCWPDGVLEFVGRMDHRIK 963 Query 950 ISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVD-DAGVTAESIRQQLADL 1008 + GY VELGE+E AL+R+PGV A L G + L AV V+ A + A S+R L Sbjct 964 VRGYGVELGEVETALRRIPGVARAVVVPLEGVTTRLVGAVSVEAGADLDANSVRAALGCA 1023 Query 1009 VPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRR 1068 +PAHM+P V LL+ +P T GK+DRA V L+ + ++ +PRT L+ AL R Sbjct 1024 LPAHMVPDTVVLLEAMPLTAVGKLDRAAVRKLV-----ETAAQAQEGVSPRTSLEAALVR 1078 Query 1069 IVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALA 1128 I+ +++G +GV DDFF+ G DS+LA + V+ IR WLDSP VAD FAART+A LA Sbjct 1079 ILGEVVG---GEIGVLDDFFSFGVDSILAIKAVSQIRDWLDSPQAAVADFFAARTVAGLA 1135 Query 1129 QLLTGREANADRLELVAEVYLEIANM 1154 + L +EA RLE VAEVYLE+A M Sbjct 1136 ERLQAKEAEPGRLEKVAEVYLEVAAM 1161 >gi|226361738|ref|YP_002779516.1| non-ribosomal peptide synthetase [Rhodococcus opacus B4] gi|226240223|dbj|BAH50571.1| non-ribosomal peptide synthetase [Rhodococcus opacus B4] Length=1153 Score = 1039 bits (2686), Expect = 0.0, Method: Compositional matrix adjust. Identities = 612/1167 (53%), Positives = 750/1167 (65%), Gaps = 37/1167 (3%) Query 4 ATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAA 63 A ++ IR V++ LG+ A+ + PG++L+G GLDSIRMM L G WR++G V+FA LAA Sbjct 4 ARISTDDIREVVSQQLGIPAERIEPGSDLIGLGLDSIRMMKLAGGWRKRGFDVNFAELAA 63 Query 64 TPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVA 123 P++E W +L+ P A P + GE FPLAPMQHA WVGR + Q+LGGVA Sbjct 64 HPSVEQWCELLGRRAPREPAA--RPDGSAPIAAGEAFPLAPMQHAYWVGRSEGQELGGVA 121 Query 124 GHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLR 183 HLYVEFDG +DP L A L HPMLR QFLPDGTQRI G F +V DLR Sbjct 122 AHLYVEFDGPALDPVALAGAVDALVAHHPMLRAQFLPDGTQRILALPGRPVF--TVVDLR 179 Query 184 HVAPDVVDQRLAGIRDAKSHQQL---DGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 + D V RL G+RD K+HQ+L DG V ++ L+ LPG R RLH+D+DM AADAMSYR Sbjct 180 DRSDDDVSTRLDGVRDMKTHQRLAVEDGQVLDITLSRLPGGRARLHLDVDMLAADAMSYR 239 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 IL+ DLA LY G E PA Y++R Y E ++ V DRDWW R+ LP PAL Sbjct 240 ILVDDLARLYGGGELPATDYSFRYY-----LERSVAHTVPKRDRDWWRSRLADLPAAPAL 294 Query 301 PTRAGGER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSR 359 P ER D + R HWLD + L A + RG+TPAM LA+ FA V+ RWS R Sbjct 295 PVVPEAERVDPCLTVRYHHWLDASAKSRLLAESHRRGVTPAMALASVFAEVIGRWSTEPR 354 Query 360 FLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAY 419 FLLNLPLF R+ HPDV+ LVGDFTSS+LL+VDL + + RA+A+Q A+ +A H+AY Sbjct 355 FLLNLPLFHREDTHPDVERLVGDFTSSVLLEVDLRDTASVSERAEALQRAMHAAGAHAAY 414 Query 420 PGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQV 479 GL VLRDL R RG VLAPVV+TSAL LG+LF T+ FG P WIISQGPQVLLDAQV Sbjct 415 TGLDVLRDLGRSRGEPVLAPVVYTSALNLGELFSEGATDIFGEPVWIISQGPQVLLDAQV 474 Query 480 TEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDA--WDAPSPSALPAAQRA 537 TE GG+L+NWDVR F PGVIDAMF + RLA DA W A + ALPA QR Sbjct 475 TEVSGGLLLNWDVRTSAFRPGVIDAMFARYTAAVDRLA---DAGFWTARAAPALPADQRE 531 Query 538 VRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAV-FASSGDLSYAQLRDQASAVAAALRA 596 R +N T A LH+GFF A P PAV + + G +Y +L D+A V AAL Sbjct 532 TRTRVNATTVAVPRNTLHEGFFGHAAVDPGHPAVLWGADGCSTYGELADRALRVGAALTD 591 Query 597 AGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVC 656 AG+ GD VAV P+ Q+ AVLG+LAAGGVY+P+G QP R RILAT V A+ Sbjct 592 AGVGAGDAVAVQLPQGPVQIVAVLGVLAAGGVYVPVGFHQPEARRARILATAGVVAAITT 651 Query 657 GPPCQVRVPVPTLLLADVLAAAPAEFVPGPS--DPTALAYVLFTSGSTGEPKGVEVAHDA 714 P +P L + AA +P P+ DP LAYVLFTSGSTG PKGVEV H A Sbjct 652 DPATFDGTGIPALAVE--AAATHPSPLPDPARPDPEELAYVLFTSGSTGTPKGVEVPHRA 709 Query 715 AMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWA 774 AMNT+ FE+GAADR LA++ LE D+SV D+F L +GG +V VD+A R+ PD W Sbjct 710 AMNTIADLNARFEIGAADRCLAVSALEFDLSVYDLFGLLSAGGTVVAVDDANRQSPDGWV 769 Query 775 RLIDTYEVTALNFMPGWLDMLLEVGGGRLS-SLRAVAVGGDWVRPDLARRLQVQAPSARF 833 + + VT LN +P LDM+L VGG L+ SLR V VGGD V DL RR+ Q P RF Sbjct 770 DAVRRHGVTVLNCVPSILDMMLSVGGDALAGSLRVVIVGGDVVGVDLPRRVAAQLPGCRF 829 Query 834 AGLGGATETAVHATIFEVQDAANLPPD-WASVPYGVPFPNNACRVVADSGDDCPDWVAGE 892 AGLGG TETA+H+TI EV + PPD W SVPYG P N CRVV +G DCP+WVAGE Sbjct 830 AGLGGTTETAIHSTICEVVE----PPDFWRSVPYGTPLGNVQCRVVNTAGLDCPEWVAGE 885 Query 893 LWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISG 952 LW+ G G+ARGYRG PE +A+RFV G+ WYRTGDLARYW DGTLEF+GRADH+V+I G Sbjct 886 LWIGGDGVARGYRGDPERSADRFVAVGGQRWYRTGDLARYWPDGTLEFLGRADHQVQIRG 945 Query 953 YRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAH 1012 YR+ELGE+EAAL+ LP VH A A ++ + LAAAV + + A + QLA L+PA Sbjct 946 YRIELGEVEAALRSLPPVHLAVAAIVGTTTPKLAAAVTI--STTPASDLAGQLAALLPAQ 1003 Query 1013 MIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVAD 1072 MIP + L+ P T +GK+DR + A+L + G + + APRT L+ AL +V Sbjct 1004 MIPERIVTLETFPLTPNGKLDRRALWAVL----DDDGAATPAFVAPRTSLEAALADVVGT 1059 Query 1073 ILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLT 1132 +L R VG DDFFALGGDSVLAT +A IR WLD+P VAD+FAART+A LA L Sbjct 1060 VLERRE--VGASDDFFALGGDSVLATTAIARIRDWLDAPHATVADIFAARTVAELAHRLD 1117 Query 1133 GREANADRLELVAEVYLEIANMTSADV 1159 +A RLE VAEVYLE+A M ++ Sbjct 1118 ANDAVPGRLERVAEVYLEVAGMDDEEI 1144 >gi|183983669|ref|YP_001851960.1| phenyloxazoline synthase MbtB [Mycobacterium marinum M] gi|183176995|gb|ACC42105.1| phenyloxazoline synthase MbtB [Mycobacterium marinum M] Length=1163 Score = 1031 bits (2667), Expect = 0.0, Method: Compositional matrix adjust. Identities = 599/1168 (52%), Positives = 756/1168 (65%), Gaps = 37/1168 (3%) Query 11 IRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAW 70 IRA +A L A + +L+ GL+SIRMMS+ GRWR++G + FA LAAT T+++W Sbjct 14 IRAAIAAQLDCPAADVADDDDLIQLGLNSIRMMSMAGRWRKRGADITFAQLAATATVQSW 73 Query 71 SQLVSAGT-GVAPTAVAAPGDAGLSQEG--EPFPLAPMQHAMWVGRHDHQQLGGVAGHLY 127 +L++A G A TA A ++ L E PFPLA MQHA W+GR D Q+LGGVA HLY Sbjct 74 HELLNADQLGCAVTAPADRPESLLEPEAPQAPFPLATMQHAYWIGRSDEQELGGVAAHLY 133 Query 128 VEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAP 187 VEFDG +DP+RL A + L HPMLR +FL DGTQ+ P+ G F ++ DLR +P Sbjct 134 VEFDGTGIDPERLERAVSDLVAVHPMLRTRFLADGTQQTMPSPGRPVF--ALVDLRGQSP 191 Query 188 DVVDQRLAGIRDAKSHQQL---DGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLA 244 D V+ L +R+ HQ+L DG V + LTL G+R+RLH+D+DM A DAMSYR+L++ Sbjct 192 DEVESALLQMRERNGHQRLAIEDGQVIDFTLTLWDGDRSRLHLDVDMLAGDAMSYRVLVS 251 Query 245 DLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRA 304 DLA LY G + G++YR YR E + + R+ DR WW +R+P++ P LPT A Sbjct 252 DLAQLYRGATLQSPGFSYRRYRTEYEPD----RAARERDRQWWQRRLPEMAGAPQLPTVA 307 Query 305 GGERDRRRSTRRW-HWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLN 363 E T R+ HWL P+ + L A A ARG+TPAM LAA FA+ + WS +FLLN Sbjct 308 VREPGAPHRTERYEHWLAPEAKQQLMAGAHARGVTPAMALAAVFADTIGGWSEQGKFLLN 367 Query 364 LPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLS 423 +PLF R+++HPD+D +VGDFTSS++L+VD+T + A RA+ +Q + + H+AY GL Sbjct 368 VPLFQRESVHPDIDRVVGDFTSSIMLEVDVTEDVSVAQRARDIQRRMYESGSHAAYSGLE 427 Query 424 VLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFD 483 VLRDL R RG VLAPVVFTSAL LG+LF +V E FG P WIISQGPQVLLDAQVTE Sbjct 428 VLRDLGRCRGEPVLAPVVFTSALDLGELFADEVIETFGDPVWIISQGPQVLLDAQVTELR 487 Query 484 GGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALN 543 GG+LVNWD RE F PG+ID MF D + RLA GD WDA +P LPAAQ A RAA N Sbjct 488 GGLLVNWDARESAFPPGLIDTMFNRFTDAVKRLADGDAGWDASAPVQLPAAQAATRAATN 547 Query 544 GRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGD----LSYAQLRDQASAVAAALRAAGL 599 S + LH GFF A PDAPAV GD SY +LR Q+ AVAA L G+ Sbjct 548 ATDGPASEKCLHQGFFEHAAANPDAPAVVWDVGDDGGVWSYRELRRQSLAVAATLHECGV 607 Query 600 RVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLAL-VCGP 658 R GD VAV PK Q+ AVLG+LAAGG Y+PIG DQP R +IL T V AL V G Sbjct 608 RPGDAVAVQLPKGRAQIPAVLGVLAAGGTYVPIGFDQPEARRAKILQTADVVAALTVEGA 667 Query 659 PCQVRVPVPTLLLA-DVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMN 717 +P ++ A D P P D +AYV+FTSGSTG PKGV+V H AAMN Sbjct 668 RMGDAIPCVSIDTARDHPKPLPEPVFP---DIGEIAYVIFTSGSTGLPKGVDVPHCAAMN 724 Query 718 TVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLI 777 T++ F +G+ADR LAL+ LE D SV DIF GG++V VD Q+ P +W L+ Sbjct 725 TIDAVNEWFGVGSADRVLALSALEFDASVYDIFGMFAVGGSLVAVDAEQKSAPTSWVELL 784 Query 778 DTYEVTALNFMPGWLDMLLEVGGGRL-SSLRAVAVGGDWVRPDLARRLQVQAPSARFAGL 836 + V+ LN +P LDM+L++GG RL +SLRAV +GGDWV DLARRL Q P RF+GL Sbjct 785 VHHRVSILNCVPSMLDMILDLGGDRLGNSLRAVTLGGDWVGADLARRLARQVPGCRFSGL 844 Query 837 GGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVS 896 GGATETA+H TI EV P WA+VP+G P N CR+V+ SG DC DWVAGELWV Sbjct 845 GGATETAIHNTICEV--VGEPPAHWATVPFGRPLRNVRCRIVSPSGRDCLDWVAGELWVG 902 Query 897 GRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVE 956 G +A YR P+ TAERFVEH G WY+TGD+ARYW DGT+EF+GRADH+V+I GYRVE Sbjct 903 GANVAARYRNDPQRTAERFVEHQGIRWYKTGDMARYWPDGTIEFLGRADHQVQIRGYRVE 962 Query 957 LGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPR 1016 LGE+E AL+ + GV A A V+ + L AAV D T I LADL+P++M+P Sbjct 963 LGEVENALRAVSGVRHAVAAVVGASAPKLVAAVAADPN--TVGDISAVLADLLPSYMVPT 1020 Query 1017 HVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGR 1076 +R P T +GK+DR V ALL E + DR APR ++ AL IVA++L + Sbjct 1021 RTVFFERFPLTANGKLDRRAVTALLEPEACTTEDR-----APRNDVEAALAEIVAEVLDQ 1075 Query 1077 ANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREA 1136 A+ VGVHDDFFALGGDSVLAT V+A IR WLD ++VAD+FAART+ ALAQ L REA Sbjct 1076 AS--VGVHDDFFALGGDSVLATAVIARIRDWLDIDHVVVADLFAARTVGALAQRLQDREA 1133 Query 1137 ---NADRLELVAEVYLEIANMTSADVMA 1161 +RL ++A YL++A +T +V+A Sbjct 1134 ARGTPERLSVIARHYLDVAALTDEEVLA 1161 >gi|317506255|ref|ZP_07964074.1| amino acid adenylation domain-containing protein [Segniliparus rugosus ATCC BAA-974] gi|316255501|gb|EFV14752.1| amino acid adenylation domain-containing protein [Segniliparus rugosus ATCC BAA-974] Length=1189 Score = 1028 bits (2659), Expect = 0.0, Method: Compositional matrix adjust. Identities = 599/1183 (51%), Positives = 754/1183 (64%), Gaps = 40/1183 (3%) Query 9 EIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIE 68 E IR +VA LLGV A++L +L+ GLDS+RMMSL GRWR++G AV FA LAA PT+ Sbjct 26 EDIRDQVAGLLGVPAESLAQDDDLISFGLDSLRMMSLAGRWRKRGFAVGFAELAANPTLR 85 Query 69 AWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVAGHLYV 128 W ++ A + A A + + EPFPLAPMQHA WVGR Q+LGGVA HLYV Sbjct 86 CWCDILRAAPRLETRAAPAAPEPEAQESAEPFPLAPMQHAQWVGRDGGQRLGGVAAHLYV 145 Query 129 EFDGAR-----VDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLR 183 EFDGA +DPDRL +A +L RHPMLRVQ LPDGTQ++ P + F DLR Sbjct 146 EFDGAGSGGAGIDPDRLASAVDQLVRRHPMLRVQVLPDGTQQVLPKPKLQIF--EAVDLR 203 Query 184 HVAPDVVDQRLAGIRDAKSHQQL---DGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 D RLA IR+AKS Q L +G V ++ L LPG R+RL +D+DM AADAMSYR Sbjct 204 EADEDEARLRLAEIREAKSSQTLAVHEGQVIDVLLVSLPGGRSRLCLDVDMIAADAMSYR 263 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 +L+ADLAALY G +L +++R+ + + P +ADR WWA R+ +LP PP L Sbjct 264 VLVADLAALYQGE---SLEKPQKDFRRHLVEKLAACDPASEADRLWWAGRLEELPSPPQL 320 Query 301 PTRAGGER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSR 359 P A + R+ R HWL P+ + AL+AR G+TPAM LA+ FA + WSA+ + Sbjct 321 PVVAEADYAPDARTVRHHHWLAPERKAALYARCHEHGVTPAMALASIFAAAVGNWSANPK 380 Query 360 FLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAY 419 FLLNLPLF+R+ +D +VGDFTSS++L VDL+ T RA VQ A AA HSAY Sbjct 381 FLLNLPLFTREETEAGLDRVVGDFTSSVMLGVDLSAPATVGERAHEVQRAFHEAAAHSAY 440 Query 420 PGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQV 479 GLSVLRDLSR G QVLA VV+TSA+GLG+LF VT+ FG+P IISQGPQV LDAQV Sbjct 441 SGLSVLRDLSRLHGEQVLANVVYTSAIGLGELFADSVTQTFGSPVHIISQGPQVALDAQV 500 Query 480 TEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPS-ALPAAQRAV 538 TE GG+L+NWDVRE PG +AMF E+ RLA + W PS + A QRA Sbjct 501 TEVSGGLLLNWDVREPYLRPGAAEAMFAWYTAEVDRLADNAEQWSRPSGAGAASKDQRAA 560 Query 539 RAALNGRTAAP--STEALHDGFFRQAQQQPDAPAVFASSG-DLSYAQLRDQASAVAAALR 595 R AL AP S + LH GFF A++ PDA AV A G SY +LR+QA AVA AL Sbjct 561 RDALFDPGPAPQGSGQTLHGGFFECAEENPDAVAVIAQDGTTTSYGKLREQALAVAGALV 620 Query 596 AAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALV 655 +G++ GD VAV PK QV A+LGILAAG Y+P+GVDQP R +++ T V + Sbjct 621 DSGVKRGDAVAVALPKGAAQVPALLGILAAGAAYVPVGVDQPPARRQQMAQTADVRAVIA 680 Query 656 CGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTA--LAYVLFTSGSTGEPKGVEVAHD 713 VP + A AA +P P T LAYVLFTSGSTG PKGVE+ H Sbjct 681 AADEDLAAPGVPVVAFAR--AAEHCRPLPQPVPVTGDDLAYVLFTSGSTGVPKGVELRHG 738 Query 714 AAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAW 773 AAMNT+E + FE+ +DR L+LA LE DMSV D+F L GGA+VV+DE+ RR+P W Sbjct 739 AAMNTLEDLVWRFEIAESDRCLSLAALESDMSVFDVFVPLGVGGAVVVIDESSRREPATW 798 Query 774 ARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARF 833 ARL++ + VT +N++PGWLD+LL+ G L SLR V +GGDWV DL RRL+ +AP +RF Sbjct 799 ARLVERHAVTCVNWIPGWLDILLDTPSGDLGSLRVVLLGGDWVSVDLPRRLRERAPRSRF 858 Query 834 AGLGGATETAVHATIFEVQDAANLPPD-WASVPYGVPFPNNACRVVADSGDDCPDWVAGE 892 AGLGGATETA+HA++ EV + P D W SVPYG P CRVV G+DCPDW GE Sbjct 859 AGLGGATETAIHASVCEV----DQPQDGWLSVPYGRPLRGMRCRVVNARGEDCPDWAVGE 914 Query 893 LWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISG 952 +W G GIA GYRG TAERFV+H+G WYRTGDL R+W GT+EFVGRADHRVKISG Sbjct 915 IWFGGPGIAEGYRGDAARTAERFVQHEGMRWYRTGDLGRHWPGGTVEFVGRADHRVKISG 974 Query 953 YRVELGEIEAALQRLPGVHAAAATVLPG-----GSDVLAAAVCVDDAGVTAESIRQQLAD 1007 YRVELGE+E+AL++ P V A A L G+ + AA + + LA Sbjct 975 YRVELGEVESALRQAPRVLRAVALALGEPTARMGTRIAAAVAGAPGNRPDTDEVLAALAR 1034 Query 1008 LVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALR 1067 +P HM+P + +L+ +P TD+GK+DRA V LL E +G + APRT L+ AL Sbjct 1035 SMPQHMVPTQLLVLESMPLTDNGKLDRAAVRRLL----EEAGPTRS-QRAPRTKLEAALV 1089 Query 1068 RIVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAAL 1127 RI+ D+LGR +G +DFF G DS+ A + VA IR WLDSPS VAD FAART+A L Sbjct 1090 RILHDVLGR---EIGAEEDFFRFGVDSIFAIKAVARIRDWLDSPSAAVADFFAARTVAGL 1146 Query 1128 AQLLTGREANADRLELVAEVYLEIANMTSADVMAALDPIEQPA 1170 A+ L ++ RLE VAEVYLE+A+++ +++A + E A Sbjct 1147 ARRLAEKDGEPGRLEQVAEVYLEVADLSEDELLAQTNEEESYA 1189 >gi|118618904|ref|YP_907236.1| phenyloxazoline synthase MbtB [Mycobacterium ulcerans Agy99] gi|118571014|gb|ABL05765.1| phenyloxazoline synthase MbtB [Mycobacterium ulcerans Agy99] Length=1163 Score = 1026 bits (2653), Expect = 0.0, Method: Compositional matrix adjust. Identities = 595/1168 (51%), Positives = 755/1168 (65%), Gaps = 37/1168 (3%) Query 11 IRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAW 70 IRA +A L A + +L+ GL+SIRMMS+ GRWR++G + FA LAAT T+++W Sbjct 14 IRAAIAAQLDCPAADVADDDDLIQLGLNSIRMMSMAGRWRKRGADITFAQLAATATVQSW 73 Query 71 SQLVSAGT-GVAPTAVAAPGDAGLSQEG--EPFPLAPMQHAMWVGRHDHQQLGGVAGHLY 127 +L++A G A TA A + L E PFPLA MQHA W+GR D Q+LGGVA HLY Sbjct 74 HELLNADQLGCAVTAPADRPELLLEPEAPQAPFPLATMQHAYWIGRADEQELGGVAAHLY 133 Query 128 VEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAP 187 VEFDG +DP+RL A + L HPMLR +FL DGTQ+ P+ G F ++ DLR + Sbjct 134 VEFDGTGIDPERLERAVSDLVAVHPMLRTRFLADGTQQTMPSPGRPVF--ALVDLRGQSA 191 Query 188 DVVDQRLAGIRDAKSHQQL---DGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLA 244 D V+ L +R+ HQ+L DG V + LTL G+R+RLH+D+DM A DAMSYR+L++ Sbjct 192 DEVESALLQMRERNGHQRLAIEDGQVIDFTLTLWDGDRSRLHLDVDMLAGDAMSYRVLVS 251 Query 245 DLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRA 304 DLA LY G + G++YR YR E + + R+ DR WW +R+P++ P LPT A Sbjct 252 DLAQLYRGATLQSPGFSYRRYRTEYEPD----RAARERDRQWWQRRLPEMAGAPQLPTVA 307 Query 305 GGERDRRRSTRRW-HWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLN 363 E T R+ HWL P+ + L A A ARG+TPAM LAA FA+ + WS +FLLN Sbjct 308 VREPGAPHRTERYEHWLAPEAKQQLMAGAHARGVTPAMALAAVFADTIGGWSEQGKFLLN 367 Query 364 LPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLS 423 +PLF R+++HPD+D +VGDFTSS++L+VD+T + A RA+ +Q + + H+AY GL Sbjct 368 VPLFQRESVHPDIDRVVGDFTSSIMLEVDVTEDVSVAQRARDIQRRMYESGSHAAYSGLE 427 Query 424 VLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFD 483 VLRDL R+RG +LAPVVFTSAL LG+LF +V E FG P WIISQGPQVLLDAQVTE Sbjct 428 VLRDLGRYRGEPMLAPVVFTSALDLGELFADEVIETFGDPVWIISQGPQVLLDAQVTELR 487 Query 484 GGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALN 543 GG+LVNWD RE F PG+ID MF D + RLA GD WDA +P LPAAQ A RAA N Sbjct 488 GGLLVNWDARESAFPPGLIDTMFNRFTDAVKRLADGDAGWDASAPVQLPAAQAATRAATN 547 Query 544 GRTAAPSTEALHDGFFRQAQQQPDAPAVFASSGD----LSYAQLRDQASAVAAALRAAGL 599 S + LH GFF PDAPAV GD SY +LR Q+ AVAA L G+ Sbjct 548 ATDGPASEKCLHQGFFEHGAANPDAPAVVWDVGDDGGVWSYRELRRQSLAVAATLHECGV 607 Query 600 RVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLAL-VCGP 658 R GD VAV PK Q+ AVLG+LAAGG Y+PIG DQP R +IL T +V AL V G Sbjct 608 RPGDAVAVQLPKGRAQIPAVLGVLAAGGTYVPIGFDQPEARRAKILQTANVVAALTVEGA 667 Query 659 PCQVRVPVPTLLLA-DVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMN 717 +P ++ A D +P P D +AYV+FTSGSTG PKGV+V H AAMN Sbjct 668 RMGDAIPCVSIDTARDHPKPSPEPVFP---DIGEIAYVIFTSGSTGLPKGVDVPHSAAMN 724 Query 718 TVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLI 777 T++ F +G+ADR LAL+ LE D SV DIF GG++V VD Q+ P W L+ Sbjct 725 TIDAVNEWFGVGSADRVLALSALEFDASVYDIFGMFAVGGSLVAVDAEQKSAPTTWVELL 784 Query 778 DTYEVTALNFMPGWLDMLLEVGGGRL-SSLRAVAVGGDWVRPDLARRLQVQAPSARFAGL 836 + V+ LN +P LDM+L++GG RL +SLRAV +GGDWV DLARRL Q P RF+GL Sbjct 785 VHHRVSILNCVPSMLDMILDLGGDRLGNSLRAVTLGGDWVGADLARRLARQVPGCRFSGL 844 Query 837 GGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVS 896 GGATETA+H TI EV P WA+VP+G P N CR+V+ SG DC DWVAGELWV Sbjct 845 GGATETAIHNTICEV--VGEPPAHWATVPFGRPLRNVRCRIVSPSGRDCLDWVAGELWVG 902 Query 897 GRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVE 956 G +A YR P+ TAERFVEH G WY+TGD+ARYW DGT+EF+GRADH+V+I GYRVE Sbjct 903 GANVAARYRNDPQRTAERFVEHQGIRWYKTGDMARYWPDGTIEFLGRADHQVQIRGYRVE 962 Query 957 LGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPR 1016 LGE+E AL+ + GV A A V+ + L AAV D T I LADL+P++M+P Sbjct 963 LGEVENALRAVSGVRHAVAAVVGASAPKLVAAVAADPN--TVGDITAVLADLLPSYMVPT 1020 Query 1017 HVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGR 1076 +R P T +GK+DR V ALL E + DR APR ++ AL IVA++L + Sbjct 1021 RTVFFERFPLTANGKLDRRAVTALLEPEACTTEDR-----APRNDVEAALAEIVAEVLDQ 1075 Query 1077 ANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREA 1136 A+ +GVHDDFFALGGDSVLAT V+A IR WLD ++VAD+FAART+ ALAQ L REA Sbjct 1076 AS--IGVHDDFFALGGDSVLATAVIARIRDWLDIDHVVVADLFAARTVGALAQRLQDREA 1133 Query 1137 ---NADRLELVAEVYLEIANMTSADVMA 1161 +RL ++A YL++A +T +V+A Sbjct 1134 ARGTPERLSVIARHYLDVAALTDEEVLA 1161 >gi|169629210|ref|YP_001702859.1| putative phenyloxazoline synthase MbtB [Mycobacterium abscessus ATCC 19977] gi|169241177|emb|CAM62205.1| Putative phenyloxazoline synthase MbtB [Mycobacterium abscessus] Length=1155 Score = 1024 bits (2648), Expect = 0.0, Method: Compositional matrix adjust. Identities = 600/1173 (52%), Positives = 755/1173 (65%), Gaps = 51/1173 (4%) Query 11 IRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAW 70 I+ VA+L+G+ A + G +L+ GLDSIRMM+L G WR++G V FA LAA P++++W Sbjct 9 IKLTVADLIGLTAQDISDGDDLITLGLDSIRMMTLAGGWRKRGSRVTFAQLAAEPSVDSW 68 Query 71 SQLVSAGTGVAPTAVAAPGDAGLSQEGE--PFPLAPMQHAMWVGRHDHQQLGGVAGHLYV 128 L+ A VAP AA D Q+GE PFPLA MQHA W+GR + Q+LGGVA HLYV Sbjct 69 YALLRADDEVAPDEEAA-ADETDGQDGEDAPFPLATMQHAYWIGRSEDQELGGVAAHLYV 127 Query 129 EFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPD 188 EFDG +DPDRL+AA RL HPMLR +FLPDGTQ+ A G F +V DLR A Sbjct 128 EFDGGAIDPDRLKAAVERLVAAHPMLRTKFLPDGTQQTMAAPGRDVF--TVVDLRGRAAG 185 Query 189 VVDQRLAGIRDAKSHQQL---DGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLAD 245 VD LA +R+ K+HQ+L DG V ++ LTL +RLH+D+DM A DAMSYR+L++D Sbjct 186 EVDAALAELREHKTHQRLAIEDGQVLDVTLTLRDDNNSRLHLDVDMLAGDAMSYRVLISD 245 Query 246 LAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTRAG 305 LAALY G P LGY+YR YR E+ + DR WW R+ LP P LP Sbjct 246 LAALYHGGAQPELGYSYRRYR----TEDRGDAAAHERDRQWWQDRLADLPGAPELPVVPV 301 Query 306 GER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLNL 364 ER D+ R+ R +WL+P+ + L A RGITPAM +AA FA + WSA SRFLLN+ Sbjct 302 SERTDQHRTVRYNYWLEPEAKQQLLVAAHQRGITPAMAMAAVFAETIGGWSAQSRFLLNV 361 Query 365 PLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLSV 424 PLF R+++HPD+D ++GDFTSS++LDVDLT + A RA+A+Q + + HSAYPGL+V Sbjct 362 PLFHRESVHPDIDRVIGDFTSSIMLDVDLTEDMSVADRARALQRTMYESGAHSAYPGLNV 421 Query 425 LRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDG 484 LRDL RHRG VLAP+V+TSAL LG+LF V + FG P WIISQGPQVLLDAQVTE G Sbjct 422 LRDLGRHRGEPVLAPIVYTSALNLGELFAEPVMQTFGEPVWIISQGPQVLLDAQVTEVRG 481 Query 485 GVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNG 544 G+L+NWDVRE F G++ AMF D + L G D W++ + LPA+Q VR A+N Sbjct 482 GLLLNWDVRESAFPHGMVAAMFERYTDAVAALCTGADGWNSDAAVRLPASQERVRRAVNA 541 Query 545 RTAAPST-EALHDGFFRQAQQQPDAPAVFASSGD----LSYAQLRDQASAVAAALRAAGL 599 TA P T LH+GFF AQ P PAV GD SY + QA AVA ALR G+ Sbjct 542 -TAGPVTGRRLHEGFFDFAQSNPGMPAVVWGFGDEDGVWSYRDVAAQALAVAGALRERGV 600 Query 600 RVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPP 659 R GD VAV PK +Q+ AVLG+LAAG Y+PIG DQP R IL TG +++AL Sbjct 601 RPGDCVAVQLPKGRDQIPAVLGVLAAGATYVPIGFDQPAQRRAAILETGGISVALTT--- 657 Query 660 CQVRVPVPTLLLADVLAAAPAEFVPGP------SDPTALAYVLFTSGSTGEPKGVEVAHD 713 +P+ D L+ A P P D + +AYVLFTSGSTG PKGV+V+H Sbjct 658 ADSDMPI------DHLSIDAARQYPEPLREPVLPDASQIAYVLFTSGSTGTPKGVDVSHA 711 Query 714 AAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAW 773 AAMNT++ FE+ +DR L L+ LE D+SV DIF G A+V VD AQR + W Sbjct 712 AAMNTIDALNDEFEVVTSDRALGLSALEFDLSVYDIFGMFSVGAAVVAVDAAQRAEATTW 771 Query 774 ARLIDTYEVTALNFMPGWLDMLLEVGGGRL-SSLRAVAVGGDWVRPDLARRLQVQAPSAR 832 LI + V+ +N +PG LDM+L +GGG L SLRAV +GGDWV DLARRL Q P R Sbjct 772 VELIRRHRVSIINCVPGLLDMILAMGGGELGDSLRAVILGGDWVSSDLARRLAAQVPGCR 831 Query 833 FAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGE 892 F GLGGATE A+H+TI EV + P WA++P+GVP N CRVV+ +G DC DWV GE Sbjct 832 FTGLGGATEAAIHSTICEV--LGDPPQHWATIPFGVPLRNVRCRVVSQAGRDCLDWVPGE 889 Query 893 LWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISG 952 LW+ G +A GYR PE TAERFVEHDG WYRTGD+ARYW DGT+EF+GRADH+VKI G Sbjct 890 LWIGGDSVASGYRNDPERTAERFVEHDGLRWYRTGDMARYWPDGTIEFLGRADHQVKIRG 949 Query 953 YRVELGEIEAALQRLPGV-HAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPA 1011 YRVELGE+E+AL+ +PG+ HA AA V +++AA D ++ L DL+P Sbjct 950 YRVELGEVESALRLIPGIRHAVAAVVGADAPNLVAAVAGTPDPAADYAAL---LGDLLPG 1006 Query 1012 HMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVA 1071 +MIP + LL+++P T +GK+DR V ALL D A PR L AL +V+ Sbjct 1007 YMIPARIELLEQMPLTSNGKMDRRAVTALLEQVAVGGAD-----AGPRHDLDAALVDLVS 1061 Query 1072 DILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLL 1131 +LG +++GVHDDFFA GGDSVLAT V+A +R WL +V D FA RT+A LA L Sbjct 1062 GVLG--IESMGVHDDFFARGGDSVLATAVIARVRDWLSVDHALVGDFFATRTVAGLADRL 1119 Query 1132 TGREAN---ADRLELVAEVYLEIANMTSADVMA 1161 REA+ DRL +VA YLEIA MT +V+A Sbjct 1120 LQREADRGTPDRLAVVAGHYLEIAAMTDEEVLA 1152 >gi|240169921|ref|ZP_04748580.1| phenyloxazoline synthase MbtB [Mycobacterium kansasii ATCC 12478] Length=1162 Score = 1022 bits (2642), Expect = 0.0, Method: Compositional matrix adjust. Identities = 591/1165 (51%), Positives = 738/1165 (64%), Gaps = 32/1165 (2%) Query 11 IRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAW 70 IRA +A LG AD L +L+ GL+SIRMM L G WR++G + FA LAA PT+ +W Sbjct 14 IRAAIAAELGCPADELGDHDDLIQLGLNSIRMMGLAGGWRKRGADITFAQLAAAPTVASW 73 Query 71 SQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVAGHLYVEF 130 L+S T + A AA PFPLA MQ A W+GR D Q+LGGVA HLY EF Sbjct 74 YALLSGDTASSAAAPAAVAPDEPEAHDAPFPLAGMQLAYWIGRSDEQELGGVAAHLYAEF 133 Query 131 DGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDVV 190 DG +DPDRL+ A L HPMLR +FLPDGTQ+ P G F + DLR V Sbjct 134 DGPAIDPDRLQRAVRDLVATHPMLRTRFLPDGTQQTMPKPGRPVF--TAIDLRGRGSQEV 191 Query 191 DQRLAGIRDAKSHQQL---DGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLA 247 LA +R+AK+HQ+L DG V ++ LT +RLH+D+DM A DAMSYR+L++DLA Sbjct 192 QSTLAELREAKTHQRLHIEDGQVIDITLTRYGDNHSRLHLDIDMLAGDAMSYRVLVSDLA 251 Query 248 ALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTR-AGG 306 LY G PA GY+YR YR A + + R DR WW +R+PQ+P P LPT G Sbjct 252 ELYRGAAVPAPGYSYRRYRTARQPDSV----ARQRDRQWWQRRLPQMPGAPELPTVPVGS 307 Query 307 ERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLNLPL 366 R R+ R HWL P + +L A A ARG+TPAM +AA FA+ + WSA +RFLLN+PL Sbjct 308 RRAPHRTVRYHHWLAPDAKRSLIAGAHARGVTPAMAVAALFADTVGGWSAQTRFLLNVPL 367 Query 367 FSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLSVLR 426 F R+++H DV+ ++GDFT+S++L+VD+T + A RA+ +Q + +A H+AY GL VLR Sbjct 368 FQRESVHSDVNRVIGDFTTSVMLEVDVTENMSVADRARDIQHRMYESASHAAYSGLEVLR 427 Query 427 DLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGV 486 DL R RG +LAPVVFTSAL LG+LF V + FG P WIISQGPQVLLDAQVTE GG+ Sbjct 428 DLGRQRGEAMLAPVVFTSALDLGELFADGVIQTFGEPVWIISQGPQVLLDAQVTELRGGL 487 Query 487 LVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGRT 546 LVNWDVRE F G++DAMFT + RLA GD WDA + LP+ Q VRAA+N Sbjct 488 LVNWDVRESAFPAGLVDAMFTRFAQAVDRLARGDAGWDAEAAVQLPSEQATVRAAVNATD 547 Query 547 AAPSTEALHDGFFRQAQQQPDAPAVF----ASSGDLSYAQLRDQASAVAAALRAAGLRVG 602 S LH GFF QA PDAPAV G SY +L +QA +VA AL+A G+R G Sbjct 548 GPVSGRCLHQGFFEQAAMNPDAPAVVWGLDNEDGAWSYRELGNQALSVAGALQAHGVRHG 607 Query 603 DTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQV 662 DTVAV PK +QV AVLGILAAGG Y+PIG DQP R +IL T AL + Sbjct 608 DTVAVQLPKGRDQVVAVLGILAAGGAYVPIGFDQPDARRAKILQTADAVAALTV-ESADM 666 Query 663 RVPVPTLLLADVLAAAPAEFVPGPSDP--TALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 + T L D P P P P T +AYV+FTSGSTG PKGVEV H AAMNT++ Sbjct 667 GTGI-TCLSIDAARNYPNPL-PEPVFPDITEIAYVIFTSGSTGLPKGVEVRHSAAMNTID 724 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 F +G+ DR LAL+ LE D SV DIF +GG++V VD Q+ W LI + Sbjct 725 AVNDWFAVGSTDRVLALSALEFDASVYDIFGMFSAGGSLVAVDAEQKAVATTWVELIRRH 784 Query 781 EVTALNFMPGWLDMLLEVGGGRL-SSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGA 839 V+ LN +P LDM+LE+GG +L SLRAV +GGDWV DLARRL Q P RF+GLGGA Sbjct 785 RVSILNCVPSMLDMILELGGDQLGGSLRAVTLGGDWVGADLARRLARQVPGCRFSGLGGA 844 Query 840 TETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRG 899 TETA+H TI EV A P W +VP+G P N CRVVA SG DC DWV GELWV G Sbjct 845 TETAIHHTICEV--AGEPPAHWTTVPFGRPLRNVRCRVVAPSGRDCLDWVPGELWVGGVN 902 Query 900 IARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGE 959 +A GYR P+ TA +FVEHDG WY+TGDLARYW DGT+EF+GRADH+V+I GYRVELGE Sbjct 903 VAAGYRNDPQRTARQFVEHDGLRWYKTGDLARYWPDGTIEFLGRADHQVQIRGYRVELGE 962 Query 960 IEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVT 1019 +E+AL+ +PGV A ATV+ G+ L AAV A + +A L+P +MIP + Sbjct 963 VESALRTVPGVRHAVATVVGSGAPKLVAAVAG--DADAAGDLTAAVATLLPDYMIPTRIV 1020 Query 1020 LLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRAND 1079 + +P T +GK+DR V ALL E S S + PR L+ AL I A++LG D Sbjct 1021 FFEHLPLTANGKLDRRAVAALLEPRPEDSAPAS---SGPRNDLEAALADITAEVLG--VD 1075 Query 1080 AVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREA--- 1136 +VGV DFFA GGDSVLAT ++A +R WL + +VAD+FA RT+A LA+ L REA Sbjct 1076 SVGVQQDFFASGGDSVLATTLIARVRDWLQTDHAVVADLFATRTVAGLAERLAQREARRG 1135 Query 1137 NADRLELVAEVYLEIANMTSADVMA 1161 +RL LVA YL+++ +T +V+A Sbjct 1136 TPERLGLVARHYLDVSALTDEEVLA 1160 >gi|289758508|ref|ZP_06517886.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis T85] gi|289714072|gb|EFD78084.1| phenyloxazoline synthase mbtB [Mycobacterium tuberculosis T85] Length=542 Score = 1001 bits (2589), Expect = 0.0, Method: Compositional matrix adjust. Identities = 505/506 (99%), Positives = 506/506 (100%), Gaps = 0/506 (0%) Query 1 VVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 +VHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT Sbjct 1 MVHATACSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFAT 60 Query 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG Sbjct 61 LAATPTIEAWSQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLG 120 Query 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA Sbjct 121 GVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVA 180 Query 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR Sbjct 181 DLRHVAPDVVDQRLAGIRDAKSHQQLDGAVFELALTLLPGERTRLHVDLDMQAADAMSYR 240 Query 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL Sbjct 241 ILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 Query 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF Sbjct 301 PTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRF 360 Query 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP Sbjct 361 LLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYP 420 Query 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT Sbjct 421 GLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVT 480 Query 481 EFDGGVLVNWDVREGVFAPGVIDAMF 506 EFDGGVLVNWDVREGVFAPGVIDAMF Sbjct 481 EFDGGVLVNWDVREGVFAPGVIDAMF 506 >gi|302526153|ref|ZP_07278495.1| non-ribosomal peptide synthetase [Streptomyces sp. AA4] gi|302435048|gb|EFL06864.1| non-ribosomal peptide synthetase [Streptomyces sp. AA4] Length=1117 Score = 997 bits (2578), Expect = 0.0, Method: Compositional matrix adjust. Identities = 581/1160 (51%), Positives = 716/1160 (62%), Gaps = 67/1160 (5%) Query 14 EVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAWSQL 73 +V LLG A L +L+ GLDSI +M + WRR+GI V FA LA TPT+ W ++ Sbjct 14 DVTGLLGPEAADLSEEDSLIEWGLDSIALMQVANAWRRRGIKVSFAELAKTPTLAGWRRV 73 Query 74 VSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVAGHLYVEFDGA 133 ++ +GVAP VAA E PFPLA MQHA W+GR + LG VA HLYVEFDG Sbjct 74 LAEASGVAPEPVAAVE----VDESAPFPLALMQHAYWIGRDEETTLGSVAAHLYVEFDGE 129 Query 134 RVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDVVDQR 193 VDP RL AA +L RH MLR F DG QRI R P A L H D D Sbjct 130 GVDPVRLEAAVGKLVQRHGMLRATFDDDGRQRI---LADRAQP---ALLVHDITD--DAE 181 Query 194 LAGIRDAKSHQQLD---GAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAALY 250 L IRD SH +LD G VF + L+ L RTRLHVD+DM AADA+SYR+LLADLA Y Sbjct 182 LEQIRDQSSHARLDVARGEVFRIQLSRLRDGRTRLHVDVDMLAADALSYRVLLADLARFY 241 Query 251 DGREPPALGYTYREYRQAIEAEETLPQPVRDAD----RDWWAQRIPQLPDPPALPTRAGG 306 +G EP +GY+Y Y E P R AD +DWW QRIP LP P LP Sbjct 242 EGAEPEPIGYSYPRYLAERE-------PARAADHARAKDWWQQRIPSLPSAPELPLVPEN 294 Query 307 ER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLNLP 365 ER D R TRR HWL P+ R L ARA G+TPAM +A AFA L+ WS RFLLN+P Sbjct 295 ERGDATRVTRRHHWLAPEGRKQLAARAHEHGLTPAMVVATAFAETLSAWSGQPRFLLNVP 354 Query 366 LFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLSVL 425 +F R++ HP+VD LVGDFT S+LLDVDL+ + A +A+A+QE + + A H+AY G+ VL Sbjct 355 MFDRESTHPEVDRLVGDFTGSVLLDVDLSAEASFADQAKALQERMHTGAAHAAYSGVEVL 414 Query 426 RDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGG 485 RDLSR++G QVLAPVVFTSAL LG+LF DV FG WI+SQGPQVLLDAQVTE + G Sbjct 415 RDLSRYQGEQVLAPVVFTSALNLGELFDADVRRLFGEAVWIVSQGPQVLLDAQVTEVNEG 474 Query 486 VLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGR 545 +L+NWDVRE F G+ID MF + +L DD W+ P ALPAAQ RA N Sbjct 475 LLINWDVRENAFPAGLIDDMFAAFHRLVTQLGQDDDVWERPVGGALPAAQARTRAKANAT 534 Query 546 TAAPSTEALHDGFFRQAQQQPDAPA-VFASSGDLSYAQLRDQASAVAAALRAAGLRVGDT 604 S + LH GFF A+++PDA A V+A +G L+Y +L D+A VAA L +R GD Sbjct 535 AGPRSKKLLHQGFFEHARREPDAVALVWAKNGQLTYGELADKALRVAAGL---NVRPGDA 591 Query 605 VAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVRV 664 V + PK +Q+AAVLG+LAAG Y+PIGVDQP RA+RI + Sbjct 592 VGITLPKGPDQIAAVLGVLAAGAAYVPIGVDQPPARADRIRRVAGIQ------------- 638 Query 665 PVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVETFIR 724 TL D A AE V G DP ++AYVLFTSGSTGEPKGVEV H AAMNT+E Sbjct 639 --ATLTTVDTTAELLAEPVVG--DPESIAYVLFTSGSTGEPKGVEVPHRAAMNTIEDLNE 694 Query 725 HFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTA 784 F +G DR LA++ L+ D+SV DIF +GGA+ +V+E R+D AWA L+ VT Sbjct 695 RFGIGPGDRCLAVSALDFDLSVYDIFGLFSAGGAVALVEEDDRKDARAWAELVADRGVTL 754 Query 785 LNFMPGWLDMLL-EVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETA 843 +N +P LDMLL G L+ LR V +GGDWV DL R+ AP RFAGLGG TETA Sbjct 755 VNCVPALLDMLLVSARPGELAGLRTVLLGGDWVGTDLPGRVAAHAPRCRFAGLGGTTETA 814 Query 844 VHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARG 903 +H+T+ EV A W SVPYG P N ACRVV G DCPDWV GELW+ G G+ARG Sbjct 815 IHSTVCEVHGVA---AHWRSVPYGTPLRNVACRVVDSRGRDCPDWVGGELWIGGDGVARG 871 Query 904 YRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAA 963 YR PE TA+RFV+HDG+ WYRTGDLARYW DGTLEF+GR DH+VK+ G R+ELGE+EAA Sbjct 872 YRADPERTADRFVDHDGQRWYRTGDLARYWPDGTLEFLGRRDHQVKVRGVRIELGEVEAA 931 Query 964 LQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDR 1023 L P V A V + L AAV VT + +R+ ++P HM+P V +LD Sbjct 932 LAEHPDVRRGIAGV---AGNQLVAAVA---GAVTPDEVREFARTILPPHMVPSRVVVLDE 985 Query 1024 IPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAVGV 1083 +P T +GK+DR V A AE + Y AP++ L++ L ++ A++L D VGV Sbjct 986 LPLTANGKVDRRAVAAHWTAETD-------SYEAPQSALEQVLAKVWAEVL--EVDRVGV 1036 Query 1084 HDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLEL 1143 D FFALGGDSVLAT +V +R LDS + V +FA T+ +A L E+ RL Sbjct 1037 DDPFFALGGDSVLATMIVGRLREALDSTEVTVRTLFATLTVGGMAARLLAEESVPGRLAQ 1096 Query 1144 VAEVYLEIANMTSADVMAAL 1163 VAE+YLE+ +T +DV A L Sbjct 1097 VAEIYLEVEALTESDVDAEL 1116 >gi|262200635|ref|YP_003271843.1| amino acid adenylation domain-containing protein [Gordonia bronchialis DSM 43247] gi|262083982|gb|ACY19950.1| amino acid adenylation domain protein [Gordonia bronchialis DSM 43247] Length=1174 Score = 970 bits (2508), Expect = 0.0, Method: Compositional matrix adjust. Identities = 577/1176 (50%), Positives = 721/1176 (62%), Gaps = 35/1176 (2%) Query 11 IRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAW 70 +R +VAE LG+ + +L+ GLDSIR+M + G WR++G ++FA LAA PT+ AW Sbjct 7 VRQKVAEALGISEYEIGDADDLIELGLDSIRIMKIAGGWRKQGHRLNFAQLAAEPTVAAW 66 Query 71 SQLV--------------SAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDH 116 + + A P+A + + + +PFPLAPMQHA W+GR D Sbjct 67 AARLDETRPETATSPAEDEAHVAHEPSAQESVDLESVDRADDPFPLAPMQHAFWIGRSDV 126 Query 117 QQLGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFP 176 +LGGVA HLYVEFDG +DP RL A RL HPMLR +FLPDGTQ++ P Sbjct 127 AELGGVAAHLYVEFDGDGIDPARLGEAMRRLVRLHPMLRARFLPDGTQQVLDDLPHN--P 184 Query 177 ISVADLRHVAPDVVDQRLAGIRDAKSHQQLD---GAVFELALTLLPGERTRLHVDLDMQA 233 V DLR + V L R+ KSHQ LD G V +L +TLLP R R+H D+DM A Sbjct 185 FRVHDLRQAGAEQVADELDRRREEKSHQVLDVAAGEVVDLTVTLLPDGRHRIHFDIDMLA 244 Query 234 ADAMSYRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQ 293 ADAMSYR+LLADL ALYDG +P +TYR+Y + P P R++D+ WW +R+P+ Sbjct 245 ADAMSYRLLLADLVALYDGAQPAPAAFTYRDY---LNHRAAHPDPDRESDQQWWRRRLPE 301 Query 294 LPDPPALPTRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLAR 353 LP PALP R GG D R R WLDP + L A +GITPA+ LAA FA + Sbjct 302 LPLGPALPARTGGPADSTRVVRFHRWLDPTVKQQLLDAAHRQGITPAIALAAVFAATIRG 361 Query 354 WSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSA 413 WS + RFLLN+PLF R+ +HPDVD L GDF+SS+L+DVD A + + AQA+Q+ + + Sbjct 362 WSGADRFLLNVPLFHREQIHPDVDRLSGDFSSSVLIDVDADSADSLLSLAQAMQKTMHAN 421 Query 414 AGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQV 473 H+ Y L VLRDL R G VLAPVV+TSALGLG+LF DV ++ G P WIISQGPQV Sbjct 422 GSHAGYGALDVLRDLGRQHGEHVLAPVVYTSALGLGELFSDDVLDRLGEPTWIISQGPQV 481 Query 474 LLDAQVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPA 533 LDAQVTE GG+L+NWDVR F GV+DAMFT + L D WD P ALPA Sbjct 482 TLDAQVTEVRGGLLLNWDVRSAAFPDGVVDAMFTRYTSMIDELIGTDGGWDRPVVDALPA 541 Query 534 AQRAVRAALNGRTAAPST-EALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAA 592 QRAVR +N TA PST LH FF A ++P A+ G +Y +L D A AVAA Sbjct 542 EQRAVRDRVND-TAGPSTGRVLHQEFFAIAGREPHRTALLWDGGSATYGELADDALAVAA 600 Query 593 ALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNL 652 AL AAG VGD VAV PK +QVAA LG+ AAG V++PI D P R IL TG + Sbjct 601 ALHAAGAGVGDAVAVQVPKGPDQVAATLGVFAAGCVWVPIAHDHPPARRATILDTGGIRH 660 Query 653 ALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAH 712 L P V V + LA A P + P DP +AYVLFTSGSTG PKGVEV H Sbjct 661 LLGVDVPAGVPDSVTVIDLASARTAVPRD-APVVGDPEDVAYVLFTSGSTGTPKGVEVPH 719 Query 713 DAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDA 772 AAMNT++ F +G DR L +A LE D+SV DIF +GGA+V V RDP A Sbjct 720 RAAMNTIDDVNERFGVGPDDRSLTVAALEFDISVYDIFGLYSAGGAVVAVSGDAARDPAA 779 Query 773 WARLIDTYEVTALNFMPGWLDMLLEVGG----GRLSSLRAVAVGGDWVRPDLARRLQVQA 828 WA LI + V+ L +P LDMLL G SLRA +GGDWV DL RL Sbjct 780 WAELIRRHRVSILTCVPSALDMLLTAAHTDPLGLGDSLRATLLGGDWVGTDLPGRLHALV 839 Query 829 PSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDW 888 P ARFAGLGGATE A+H T+ EV + +P W ++P+G P N CRVV +G DCPDW Sbjct 840 PGARFAGLGGATEIAIHGTVCEVPPTSAVPEHWRAIPFGTPLRNVVCRVVDAAGRDCPDW 899 Query 889 VAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRV 948 V GELWV G G+A GYR PE TA+RFV DG WYRTGDLARYW DGT+EF+GRADH+V Sbjct 900 VTGELWVGGAGVAHGYRNDPERTAQRFVTVDGIRWYRTGDLARYWPDGTIEFLGRADHQV 959 Query 949 KISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVT-AESIRQQLAD 1007 KI G+RVELGE+E AL+ LPGV A A+++ G LAA + VDD G + ++ L Sbjct 960 KIRGFRVELGEVEGALRALPGVRTAVASLVADGGRSLAAVITVDDDGPSDGAAVADALRA 1019 Query 1008 LVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALR 1067 ++PA+M+P V ++D IP T +GK DR + LL+ + R+ P L+ ALR Sbjct 1020 VLPAYMVPSTVVIVDAIPLTSNGKHDRRAITTLLSRQTARN-----EIVGPAGDLEEALR 1074 Query 1068 RIVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAAL 1127 +VA+++ R D +GV DDFFA+GGDSVLAT +VA +R WLD+P V D+FA RTI AL Sbjct 1075 AVVAELISRPADEIGVTDDFFAIGGDSVLATTLVARVREWLDAPQAGVRDVFATRTIRAL 1134 Query 1128 AQLLTGREANADRLELVAEVYLEIANMTSADVMAAL 1163 A+ L + RL VA +YLE+A M V A + Sbjct 1135 ARRLDETDERPGRLAEVAALYLEVAAMDDEAVAAEV 1170 >gi|326383363|ref|ZP_08205050.1| amino acid adenylation domain-containing protein [Gordonia neofelifaecis NRRL B-59395] gi|326197769|gb|EGD54956.1| amino acid adenylation domain-containing protein [Gordonia neofelifaecis NRRL B-59395] Length=1174 Score = 959 bits (2480), Expect = 0.0, Method: Compositional matrix adjust. Identities = 598/1186 (51%), Positives = 735/1186 (62%), Gaps = 51/1186 (4%) Query 7 CSEIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPT 66 +RA++A LL V + G +L+G GLDSIRMM L G WR+ G V+FA LAA+PT Sbjct 8 SESTVRADIAALLDVDPSTIGDGDDLIGLGLDSIRMMRLAGGWRKLGHDVNFADLAASPT 67 Query 67 IEAWSQLVSAGTG--VAPTAVAAPGDAGLSQE---GEPFPLAPMQHAMWVGRHDHQQLGG 121 + WS ++ A + V G G E + FPLAPMQHA WVGR LGG Sbjct 68 VADWSAMLGAADAEPAGASGVTEQGIGGFDAEDWAADSFPLAPMQHAYWVGRTGAADLGG 127 Query 122 VAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFP---IS 178 VA HLYVEFDGA +DPDRL AAA L RH MLR +F DG Q++ A P + Sbjct 128 VAAHLYVEFDGAGLDPDRLAAAAEALVARHGMLRARFGADGRQQVLDA-----LPRPALV 182 Query 179 VADLRHVAPDVVDQRLAGIRDAKSHQQLD---GAVFELALTLLPGERTRLHVDLDMQAAD 235 V DLR +++ L R++KSHQ LD G VF+L LTLLPG R RLH D+DM AAD Sbjct 183 VDDLRGTDSADIERLLTERRESKSHQVLDIAAGQVFDLTLTLLPGGRHRLHFDIDMLAAD 242 Query 236 AMSYRILLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLP 295 AMSYR LL DL ALYDG + P L YR+Y + P R ADRDWWA R+ LP Sbjct 243 AMSYRTLLRDLVALYDGAQLPPLSVGYRDY---LRHRAEHPDSARAADRDWWADRLADLP 299 Query 296 DPPALPTRAGGE--RDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLAR 353 P LP R G+ DR R R HWLD R L A A RG+TPA + A +A + Sbjct 300 GGPILPARPAGQTQSDRARVVRMNHWLDAGARAGLLAAAHERGVTPAAVVGAVYAASVGA 359 Query 354 WSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLT-----GARTAAARAQAVQE 408 WS++ FLLN+PLF R +H ++D + GDF+SS+L+DVDL G + A+ VQ Sbjct 360 WSSTPHFLLNVPLFQRVPMHDEIDAVSGDFSSSILVDVDLRVLTAPGNGSVLDLARDVQR 419 Query 409 ALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIIS 468 + A HSAY L +LRDL R RG VLAPVVFTSALGLG+LF +V + G P I+S Sbjct 420 RMHEAGSHSAYGALDILRDLGRLRGETVLAPVVFTSALGLGELFADEVYARLGRPAHIVS 479 Query 469 QGPQVLLDAQVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDA--WDAP 526 QGPQVLLDAQ+TE GG+L NWDVR F GV++AMF H L LAAG + W A Sbjct 480 QGPQVLLDAQITEVGGGLLTNWDVRIDQFPDGVVEAMFEHFTTTLDGLAAGGSSAGWLAE 539 Query 527 SPSALPAAQRAVRAALNGRTAAPST-EALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRD 585 + LPA+QRAVR +N TAAP+T LH GFF A + P+ PA+ G L+Y +L Sbjct 540 ALPQLPASQRAVRCEVN-NTAAPTTGRVLHQGFFEVAAEDPERPALLWRDGGLAYGELAP 598 Query 586 QASAVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERIL 645 QA AVAAALR+AG+R GD V V PK Q+ A LG+ AAG V++P+ DQP R IL Sbjct 599 QALAVAAALRSAGVRPGDAVGVQIPKGYRQMIATLGVYAAGAVWVPVTYDQPAPRRAAIL 658 Query 646 ATGSVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGP--SDPTALAYVLFTSGSTG 703 T L L G R+ VP L L+D LAAAP + GP DP A+AYVLFTSGSTG Sbjct 659 RTAEAALLLTDGVVEPDRLEVPALELSDALAAAP---LSGPYLPDPEAVAYVLFTSGSTG 715 Query 704 EPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVD 763 PKGVEV H AAMNT++ R F +G DR L +A LE D+SV DIF +GGA++ V Sbjct 716 TPKGVEVPHRAAMNTIDDVNRRFGVGPGDRSLTVAALEFDISVYDIFGLYSAGGAVIAVG 775 Query 764 EAQRRDPDAWARLIDTYEVTALNFMPGWLDMLL-----EVGGGRLS-SLRAVAVGGDWVR 817 +DP AW L+ + + L +P LDMLL E GGG L SLRAV +GGDWV Sbjct 776 ADDAKDPAAWRDLLVAHRASVLTCVPSALDMLLTLAETETGGGALGDSLRAVLLGGDWVG 835 Query 818 PDLARRLQVQAPSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRV 877 DL RL+ AP ARFAGLGGATE A+H T+ EV + P W SVP+G P N ACRV Sbjct 836 ADLPGRLRSLAPGARFAGLGGATEIAIHGTVCEVSEP---PAHWTSVPFGTPLANVACRV 892 Query 878 VADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGT 937 V+D G DCPDWV+GELWV G G+A GYR P+ TAERFVE +GR WYRTGDLARYW DGT Sbjct 893 VSDLGTDCPDWVSGELWVGGDGVAHGYRNEPQRTAERFVEFEGRRWYRTGDLARYWPDGT 952 Query 938 LEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGV- 996 +EF+GRAD++VKI G+RVELGEIE AL+ LP V A A ++ G AAV + G Sbjct 953 VEFLGRADNQVKIRGFRVELGEIEGALRTLPSVRHAVAVLVAGNGPATLAAVVAPEPGSA 1012 Query 997 -TAESIRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPY 1055 + +R LADLVP +M+P + + +P T +GK+DRA + A L + S+P Sbjct 1013 PNPDELRDSLADLVPGYMVPAVIDVRAELPLTGNGKLDRAAITASLGT----TAADSSPR 1068 Query 1056 AAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMV 1115 P T L RAL I+AD+LG + +GV DDFFA GGDSVLAT V+A +R LD+P V Sbjct 1069 RDPETDLHRALLAIMADVLG-GDRELGVDDDFFAAGGDSVLATTVIARVRDLLDAPQAGV 1127 Query 1116 ADMFAARTIAALAQLLTGREANADRLELVAEVYLEIANMTSADVMA 1161 AD+FAART+ LA+ L + RLE VA +YLEIA M ++MA Sbjct 1128 ADIFAARTVDELARRLDDADERPGRLEQVAAIYLEIAAMDDEELMA 1173 >gi|269124629|ref|YP_003297999.1| amino acid adenylation domain-containing protein [Thermomonospora curvata DSM 43183] gi|268309587|gb|ACY95961.1| amino acid adenylation domain protein [Thermomonospora curvata DSM 43183] Length=1131 Score = 957 bits (2474), Expect = 0.0, Method: Compositional matrix adjust. Identities = 572/1163 (50%), Positives = 719/1163 (62%), Gaps = 48/1163 (4%) Query 9 EIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIE 68 E + + ++LG + D P NL+ G+DSIR+MSL GR R++GI + FA LA PT+ Sbjct 5 EELHQSLTQVLGEQVD---PHDNLIELGMDSIRLMSLTGRLRKRGIEITFAELAERPTLA 61 Query 69 AWSQLVSAGTGVAPTAV-AAPGD-AGLSQEGE-PFPLAPMQHAMWVGRHDHQQLGGVAGH 125 W +L++ +AP A P + A +QE + PFPLA MQHA W+GR Q+LG VA H Sbjct 62 QWWELLAERGALAPAAEPETPQEPAADAQEPDGPFPLALMQHAYWIGRDSEQELGSVAAH 121 Query 126 LYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFP-ISVADLRH 184 LYVE DG +DP RL A L RHPMLRV DGTQR+ P R P I+V DLR Sbjct 122 LYVELDGRDIDPGRLEKAVRTLVERHPMLRVAICDDGTQRVLP---ERPGPAITVLDLRR 178 Query 185 VAPDVVDQRLAGIRDAKSHQQL---DGAVFELALTLLPGERTRLHVDLDMQAADAMSYRI 241 A + L +R S Q+L G VF+L L+LLP RLH+D+DM AADAMSYR Sbjct 179 AADPQAE--LERVRREMSTQRLPIDTGKVFDLRLSLLPSGTARLHLDVDMVAADAMSYRT 236 Query 242 LLADLAALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALP 301 +LADLAALY+G P L Y+Y Y A + R+ DR WWAQR+ LP PP LP Sbjct 237 MLADLAALYEGETLPPLRYSYARYLAADPRAQA-----RERDRAWWAQRLADLPGPPELP 291 Query 302 TRAGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFL 361 + R R+ HWL P+ + L RA G+TPAM LA FA V+ WSA+ RF+ Sbjct 292 VVP---KPGHRVVRKHHWLSPEGKRQLITRAHREGVTPAMALATIFAEVIGAWSATPRFI 348 Query 362 LNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPG 421 LNLPLF R+ +HPDVD LVGDFT S+LL++DLT RA+AVQ L +A HS Y G Sbjct 349 LNLPLFHREPVHPDVDKLVGDFTGSILLEIDLTEELPFVERARAVQAKLHTAGTHSDYSG 408 Query 422 LSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTE 481 L VLRDLSR RG QVLAP+V+TSAL LG+LF V FG P WIISQGPQVLLDAQVTE Sbjct 409 LEVLRDLSRQRGEQVLAPIVYTSALNLGELFDERVRALFGEPVWIISQGPQVLLDAQVTE 468 Query 482 FDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAA 541 GG+L+NWDVRE F GV DAMF D + RL A D W P P Q +R Sbjct 469 VSGGLLLNWDVREPAFPEGVADAMFAAYTDAVTRLGAPDADWSRPLRIQAPPEQLEIRKR 528 Query 542 LNGRTAAPSTEALHDGFFRQAQQQPDAPAV-FASSGDLSYAQLRDQASAVAAALRAAGLR 600 LN R A PS L +GFF A+ P APAV + G L+Y +L D+A VA L A G+R Sbjct 529 LNARPAPPS-RTLIEGFFANARHNPQAPAVHWDDDGTLTYGELADRALRVAGHLVAQGVR 587 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 GD VA+ PK +Q AVLG+LAAG Y+PIGV+QP R E+I T + L+L Sbjct 588 PGDRVAIELPKGPDQAVAVLGVLAAGAAYVPIGVEQPPARREKITKTAQIALSLTPA--- 644 Query 661 QVRVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMNTVE 720 L LA A P P P +AYVLFTSGSTGEPKGVEV+H AAMNT+ Sbjct 645 ---------ALTWALAQAQPLAEPVPITPGQVAYVLFTSGSTGEPKGVEVSHRAAMNTIG 695 Query 721 TFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTY 780 I F LG D L ++ L+ D+SV D+FA +GGA+V+ E +R+D WA L+ Sbjct 696 DLIERFSLGPRDVSLGISALDFDLSVFDLFALWTAGGAVVIPAEEERKDAARWAELVARR 755 Query 781 EVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGAT 840 VT LN +P L+MLL+ GG + SLR V +GGDWV L L +AP RF LGG T Sbjct 756 SVTVLNCVPSVLEMLLQTGGD-VRSLRVVLLGGDWVGVHLPGMLAERAPGCRFVALGGTT 814 Query 841 ETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGI 900 ETA+H+T+ EV + +P DW +VPYGVP ACRVV + G D PDWV GELW+ G G+ Sbjct 815 ETAIHSTVQEV--SGPVPEDWHAVPYGVPLRGVACRVVDEQGRDRPDWVPGELWIGGGGV 872 Query 901 ARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEI 960 A GY G PE TA+RFV H+G WYRTGD+ARY DGTLEF+GR DH+VK+ G+R+ELGEI Sbjct 873 AEGYCGDPERTADRFVTHEGVRWYRTGDMARYRPDGTLEFLGRRDHQVKVRGFRIELGEI 932 Query 961 EAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTL 1020 EAAL+ P V A A L GS LAAA+ V + ++ + DL+P HM+P + Sbjct 933 EAALESHPRVRRAVA--LLAGSR-LAAAIVPASGEVDRQELQDHVRDLLPPHMVPELLVR 989 Query 1021 LDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDA 1080 ++ +P T +GKIDR + AL AAE + +A Y P T L++ + R + ++LG + Sbjct 990 VEELPLTANGKIDRKALTALAAAEAGEA---AATYVEPTTALEKVIARTIGEVLG--IER 1044 Query 1081 VGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADR 1140 VG DDFFALGGDSVLAT VVA +R LD+ SL V +FA RT++ +A+ T E R Sbjct 1045 VGAEDDFFALGGDSVLATTVVARLREALDTTSLPVRVIFAQRTVSRIARRFTELEETPGR 1104 Query 1141 LELVAEVYLEIANMTSADVMAAL 1163 LE VA+++L +A+MT +V A L Sbjct 1105 LEAVADIWLTVADMTDEEVEAHL 1127 >gi|158317684|ref|YP_001510192.1| amino acid adenylation domain-containing protein [Frankia sp. EAN1pec] gi|158113089|gb|ABW15286.1| amino acid adenylation domain [Frankia sp. EAN1pec] Length=1678 Score = 929 bits (2400), Expect = 0.0, Method: Compositional matrix adjust. Identities = 590/1228 (49%), Positives = 725/1228 (60%), Gaps = 84/1228 (6%) Query 9 EIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIE 68 E +R VAEL+ A+ ANL GL+SI +M VGRWRR G+AV FA LA PT++ Sbjct 463 EDVRRIVAELIDEDPSAIGNEANLFELGLESIALMKAVGRWRRAGMAVSFAELAENPTVD 522 Query 69 AWSQLVSAGTGVAPTAVAAPGDAGLSQ-EGEPFPLAPMQHAMWVGRHDHQQLGGVAGHLY 127 W +L+S APT A D ++ E FPLA MQHA WVGR Q LG VA HLY Sbjct 523 GWCKLLSM---RAPTEPAGADDGAQARAEAGEFPLALMQHAYWVGRDGGQPLGEVAAHLY 579 Query 128 VEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAP 187 EFDGA VD DRLR A L RH MLRV+ +G+Q + +G R ++V DLR + Sbjct 580 TEFDGAGVDVDRLRTAIEALVARHDMLRVRITDNGSQVVEATSGWRG--LTVHDLRELGQ 637 Query 188 DVVDQRLAGIRDAKSHQQLD---GAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLA 244 RLA +RD SHQ LD G VF AL+LLP RTRLH+D+DM AADA+SYR+LL Sbjct 638 AETQARLAAVRDRMSHQMLDIEHGEVFATALSLLPQGRTRLHLDVDMVAADAVSYRVLLN 697 Query 245 DLAALYD--GREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPT 302 DLA YD G E P LGYTYREYR A A +WW R+P LP P LP Sbjct 698 DLARFYDRPGEEHPPLGYTYREYRAARVPARRA---AARAAAEWWQGRLPGLPGAPGLPR 754 Query 303 RAGGE--------------------RDRRRSTRRWHWLDPQTRDALFARARARGITPAMT 342 A + + R TRR L P R AL A +RG+TPAM Sbjct 755 LASPDDAGTASSAGAASTAGATGSTGEPPRVTRRHFVLGPSARQALQRAAHSRGVTPAMA 814 Query 343 LAAAFANVLARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAAR 402 +A AFA VLA WS SRF+LN+P+F R +H DV+ +VGDFTSS+LL+VDL + A R Sbjct 815 VATAFAEVLAGWSTESRFVLNVPMFDRDQVHADVNQVVGDFTSSVLLEVDLAEPQPFATR 874 Query 403 AQAVQEALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGT 462 + VQ L + A H+ Y G+ VLRDL+R G QVLAPVVFTSALGLG+LF P V + FG Sbjct 875 VRQVQARLHADAAHADYSGVEVLRDLTRRTGEQVLAPVVFTSALGLGELFGPGVRQHFGD 934 Query 463 PGWIISQGPQVLLDAQVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLR-LAAGDD 521 P WIISQGPQVLLDAQVTE DGG+LVNWDVR+G FAPGV+DAMF + L+R LA Sbjct 935 PVWIISQGPQVLLDAQVTELDGGLLVNWDVRDGEFAPGVVDAMFG-AFERLVRGLADTAG 993 Query 522 AWDAPSPSALPAAQRAVRAALNGRTAAPSTEALHDGFFRQAQQQPDAPAVF----ASSGD 577 WD +P RA+RAA N T LH+GFF A PDAPA+ G Sbjct 994 TWDTAVDGLVPEPARAIRAAANDTAGPVPTRLLHEGFFENAVLAPDAPALLWDTAGGPGS 1053 Query 578 LSYAQLRDQASAVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQP 637 L+Y +LR +A +A AL G+R GD V V PK QV AVLG+LAAG Y+P+G++QP Sbjct 1054 LAYGELRRRALGLAGALAGHGVRRGDLVGVSLPKGPSQVVAVLGVLAAGATYVPVGIEQP 1113 Query 638 RDRAERILATGSVNLALVCGPPCQVRVPVPTLLLADVLAAAPAEFVPGPSDPTAL----- 692 R ERI A + ++ + VP + LA A PA VP + P L Sbjct 1114 AARVERIAA--AAGFGVLITESHRDGVPAGVVQLAPDQPAEPAP-VPDLAAPGELGGLDR 1170 Query 693 -AYVLFTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFA 751 AYVLFTSGSTG+PKGVEV H AAMNT+ I LG DR LA++ L+ D+SV DIFA Sbjct 1171 PAYVLFTSGSTGQPKGVEVGHRAAMNTIADLIDRLGLGTDDRTLAVSALDFDLSVFDIFA 1230 Query 752 ALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAV 811 L +GGA+ +VDE RR+ WA LI + VT LN +P LD++L G SLRAV + Sbjct 1231 PLSAGGAVALVDEDSRREASRWAELIRDHRVTVLNCVPTVLDLVLAAGVALGDSLRAVLL 1290 Query 812 GGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFP 871 GGD V DL RL P RF GLGG TETA+H+TI EV+ A+ LPP W VPYG P Sbjct 1291 GGDKVGVDLPGRLAAAVPGCRFLGLGGTTETAIHSTICEVEGASPLPPQWRLVPYGTPLR 1350 Query 872 NNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLAR 931 N RVV G DCPD VAGELW+ G G+ARGY G PE TA+RFVEH G WYRTGD+AR Sbjct 1351 NVRLRVVDPLGRDCPDHVAGELWIGGDGVARGYLGDPERTADRFVEHTGIRWYRTGDIAR 1410 Query 932 YWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAAAATVLPGGSD-------- 983 Y DGT++F+GR D +VKI G+RVELGE+EAAL LP V A A ++ G S Sbjct 1411 YLPDGTVDFLGRRDDQVKIRGFRVELGEVEAALTTLPEVRAGVAVLVRGASGRSAVLGGG 1470 Query 984 -------------------VLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRI 1024 D A ++R+ L +P HM+P V LD + Sbjct 1471 VVLGAGVVPATPATGEADDGGGGGESSGDGAGIAGAVREGLRRALPPHMVPDLVVALDSL 1530 Query 1025 PFTDSGKIDRAEVGALLAAEVERS-GDRSAPYAAPRTVLQRALRRIVADILGRANDAVGV 1083 P T +GKIDR V A VER+ R+A +A PRT L+R + + ++LG A G+ Sbjct 1531 PLTANGKIDRRAV----TAAVERAVAGRAADHAPPRTDLERVVHNVWREVLGVAE--FGI 1584 Query 1084 HDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLEL 1143 D+FFALGGDSVLAT +V +R LD+ ++ V +F A T+AALA+ + + R E Sbjct 1585 TDEFFALGGDSVLATALVTRLRDELDTAAVTVRSVFGAPTVAALAERIRAADTVPGRAER 1644 Query 1144 VAEVYLEIANMTSADVMAAL-DPIEQPA 1170 VA + LEIA M+ +V A L DP PA Sbjct 1645 VAAIALEIAAMSDDEVAAELVDPDTLPA 1672 >gi|134099239|ref|YP_001104900.1| non-ribosomal peptide synthase [Saccharopolyspora erythraea NRRL 2338] gi|133911862|emb|CAM01975.1| non-ribosomal peptide synthase [Saccharopolyspora erythraea NRRL 2338] Length=1167 Score = 904 bits (2336), Expect = 0.0, Method: Compositional matrix adjust. Identities = 584/1169 (50%), Positives = 717/1169 (62%), Gaps = 46/1169 (3%) Query 15 VAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAWSQLV 74 +AEL+ + + ANL GLDSI +M LV RWR+ G+ DFA LA PT+ W++L+ Sbjct 18 LAELVEEEPEDVRASANLFELGLDSIDLMKLVSRWRQAGVQADFAELAHRPTVRDWARLL 77 Query 75 S--AGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVAGHLYVEFDG 132 + T P A D G + + E F LA MQHA WVGR QQLGGVA HLY EFDG Sbjct 78 ADRHETPAQPEHDGAVQDPGSASDAE-FDLALMQHAYWVGRTADQQLGGVAAHLYTEFDG 136 Query 133 ARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDV-VD 191 VDPDRLR+A + L RH MLRV+ DG QR+ G R + V DLR APD V+ Sbjct 137 TGVDPDRLRSALSHLVQRHDMLRVRVGDDGRQRVCAEPGWRG--LVVRDLRD-APDAEVE 193 Query 192 QRLAGIRDAKSHQQLD---GAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAA 248 Q L RDA SHQ LD G V L+LLPG RTR H+D+DM AADA+SYRILLADLA Sbjct 194 QSLERTRDAMSHQVLDIEAGEVLSTVLSLLPGGRTRFHLDVDMVAADAVSYRILLADLAR 253 Query 249 LY---DGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTR-- 303 LY D PP + Y+YREY A +E R A+ WA R+P LP P LP Sbjct 254 LYAEPDAALPP-IRYSYREY-LAARSESRDDAATRAAEH--WAARLPGLPGAPELPMAPQ 309 Query 304 --AGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFL 361 A G R R R +L P+ RD L AR G+T A +A AFA VL WS+ RFL Sbjct 310 FPAPG---RPRVVREHVFLPPEERDLLERAARRHGVTLAAAVATAFAEVLGAWSSEPRFL 366 Query 362 LNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPG 421 +N+P+F R +H DVDLLVGDFTSS+LL VDLT A R +A QE L + A H+ + G Sbjct 367 VNVPMFDRSPVHSDVDLLVGDFTSSVLLAVDLTEPLAFADRVRATQERLHADAAHAEHSG 426 Query 422 LSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTE 481 + VLRDL+R G QVLAPVVFTSAL LG+LF V E FG WI+SQGPQVLLDAQ+TE Sbjct 427 VEVLRDLTRSAGRQVLAPVVFTSALNLGELFPGGVRELFGEAVWIVSQGPQVLLDAQITE 486 Query 482 FDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAA 541 G+LVNWDVRE FA GV+ AMF + RLA DAW +P+AQ AVR Sbjct 487 VADGLLVNWDVREREFAEGVVPAMFAAFSSLVERLAGEPDAWRTQVDGMIPSAQAAVRDR 546 Query 542 LNGRTAAPSTEALHDGFFRQAQQQPDAPAVF-ASSGDLSYAQLRDQASAVAAALRAAGLR 600 +N S LH+ FF A +P+APAV LSY +L DQA V AAL G+ Sbjct 547 VNETAGPRSGRLLHEDFFAHAAAEPEAPAVLWGEDRGLSYGELADQALRVGAALLDRGVA 606 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 GD V V PK +QV AVLG+LAAGGVY+P+G+DQP RA RI A V G Sbjct 607 PGDPVGVSLPKGADQVVAVLGVLAAGGVYVPVGIDQPATRAARI--------AQVAGFQV 658 Query 661 QV---RVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMN 717 Q+ R L L D A P P D LAYVLFTSGSTGEPKGVEV H AAMN Sbjct 659 QITADRDADGALALEDAFAHPPLA-APVTQDEEQLAYVLFTSGSTGEPKGVEVPHRAAMN 717 Query 718 TVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLI 777 T+E R F LG DR LA++ L+ D+SV D+FA L +GGA+VVV E +RRD WA L+ Sbjct 718 TIEDLRRRFGLGPGDRTLAVSALDFDLSVFDVFAPLSAGGAVVVVAEEERRDAHRWAELV 777 Query 778 DTYEVTALNFMPGWLDMLLEVGGGR--LSSLRAVAVGGDWVRPDLARRLQVQAPSARFAG 835 ++V+ LN +P LD+LL G L+SLR V +GGD V DL RL AP RF Sbjct 778 RGHQVSVLNCVPPLLDVLLRAVGESQDLASLRVVLLGGDRVGVDLPGRLSAAAPGCRFIA 837 Query 836 LGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWV 895 LGG TETA+H+TI EV +LP D SVPYG P N A RVV G DCPDWVAGELW+ Sbjct 838 LGGTTETAIHSTIHEVPAGGSLPADCQSVPYGTPLRNVALRVVDALGRDCPDWVAGELWI 897 Query 896 SGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRV 955 G G+ARGYR P+ TA+RFVE GR WYRTGDLARY G +EF+GR D +VKI G+RV Sbjct 898 GGDGVARGYRADPDRTADRFVESGGRRWYRTGDLARYRPGGIVEFLGRHDDQVKIRGFRV 957 Query 956 ELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIP 1015 ELGE+EAAL V AA A S VL AAV D G +S+R+++ DL+P HM+P Sbjct 958 ELGEVEAALLDDSRVRAAVAVAHGESSPVLGAAVVTD--GTDVDSVRERVRDLLPPHMVP 1015 Query 1016 RHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILG 1075 + +++IP T +GK+DR V + VERS + APRT L+RAL + A++LG Sbjct 1016 DRLVAVEQIPLTGNGKVDRRAV----RSTVERSVRNATDRIAPRTDLERALAIVWAEVLG 1071 Query 1076 RAN-DAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGR 1134 + ++V V DDFFA GGDS+LAT++V G+R LD+ ++ V + + TIA LA + Sbjct 1072 IDDLESVSVDDDFFAAGGDSLLATKLVTGVRDALDTAAVSVRMLLSQPTIAGLADRMGAA 1131 Query 1135 EANADRLELVAEVYLEIANMTSADVMAAL 1163 E +RLE A ++ EIA ++ +V+A L Sbjct 1132 EQVPERLERAAALFCEIAALSEEEVVAQL 1160 >gi|312198337|ref|YP_004018398.1| amino acid adenylation domain protein [Frankia sp. EuI1c] gi|311229673|gb|ADP82528.1| amino acid adenylation domain protein [Frankia sp. EuI1c] Length=1673 Score = 904 bits (2335), Expect = 0.0, Method: Compositional matrix adjust. Identities = 587/1215 (49%), Positives = 719/1215 (60%), Gaps = 72/1215 (5%) Query 9 EIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIE 68 E +R VAEL+ +L NL +GL+SI ++ +G+WRR G+ V+FA LA TPT++ Sbjct 461 EALRRTVAELIEEDPASLGDDDNLFERGLESIALIRAIGQWRRAGLEVNFAELAETPTLD 520 Query 69 AWSQLVSAG------------TGVAPTAVAAPGD--AGLSQEGEPFPLAPMQHAMWVGRH 114 W +L+SA GV P + A P + AG GE FPLA MQHA W+GR Sbjct 521 GWFKLLSARRPAAAPEAVAGPAGVDPVS-AGPAETAAGPDDAGE-FPLAVMQHAYWIGRG 578 Query 115 DHQQLGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRD 174 Q GGVA HLY EFDG VDP RL AA RL RH LR + G Q + AG R Sbjct 579 AGQSYGGVAAHLYSEFDGDGVDPARLAAAVERLIQRHEALRTRITDLGGQVVEQVAGWRG 638 Query 175 FPISVADLRHVAPDVVDQRLAGIRDAKSHQQLD---GAVFELALTLLPGERTRLHVDLDM 231 ++V DLR + + +QRLA +RD SHQ LD G VF L+L P TRLH+D+DM Sbjct 639 --LAVHDLRDLDDEAAEQRLAAVRDRLSHQLLDIERGEVFATELSLRPDGTTRLHLDVDM 696 Query 232 QAADAMSYRILLADLAALYDGRE---PPALGYTYREYRQA-----IEAEETLPQPVRDAD 283 AADA SYR+LLADLA LY GR PA Y+YR YR + T Sbjct 697 VAADAGSYRVLLADLADLY-GRPDTVAPAPAYSYRRYRAERAAARLGQRGTARGEAAARA 755 Query 284 RDWWAQRIPQLPDPPAL--------PTRAGGERDRRRSTRRWHWLDPQTRDALFARARAR 335 R W R+P LP PP L P G R +RR L P R AL A Sbjct 756 RRAWFDRLPGLPGPPQLALAPATDNPAGGDGPAAAPRVSRRHFRLPPSARAALDRAAHRH 815 Query 336 GITPAMTLAAAFANVLARWSASSRFLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTG 395 G+TPAM +A AFA VL WSA RFLLN+PLF R+ LHPDV+ +VGDFTSS+LL++DLT Sbjct 816 GVTPAMAVATAFAEVLGGWSAQPRFLLNVPLFDREQLHPDVNRIVGDFTSSVLLEIDLTD 875 Query 396 ARTAAARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPD 455 RA+ VQ L + A H+ Y G+ VLRDL RH G LAPVVFTSALGLG+LF Sbjct 876 RVPFVDRARRVQTRLHADAAHADYSGVEVLRDLGRHHGEPALAPVVFTSALGLGELFDAP 935 Query 456 VTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLR 515 V +FG P WIISQGPQVLLDAQVTE DGG+LVNWD+REG FAPGV+DAMF + L+R Sbjct 936 VRREFGRPVWIISQGPQVLLDAQVTELDGGLLVNWDIREGTFAPGVVDAMFA-AFERLVR 994 Query 516 LAA--GDDA--------WDAPSPSALPAAQRAVRAALNGRTAAPSTEALHDGFFRQAQQQ 565 A G D W+ P L + R VR + ST LH+GFF A Q+ Sbjct 995 GLAEPGPDTTGLPDTTVWEQPVDGLLDPSVRDVRRRVGAVAGPASTRLLHEGFFAAAAQR 1054 Query 566 PDAPAVF---ASSG----DLSYAQLRDQASAVAAALRAAGLRVGDTVAVLGPKTGEQVAA 618 PDAPA+ A +G LSY +L +A+AVA L A G+R GD V V PK QV A Sbjct 1055 PDAPALRWDEAGTGPRRRSLSYGELAARATAVAGTLAARGVRPGDLVGVSLPKGPGQVVA 1114 Query 619 VLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQVRVPVPTLLLADVLAAA 678 VLG+LAAG Y+PIGVDQP R ERI+AT + P V L L D LA A Sbjct 1115 VLGVLAAGAAYVPIGVDQPAARIERIVATAGFRTVVTDRPGSDWPAGVTPLSLDDALAGA 1174 Query 679 PAEFVPG-----PSDPTAL---AYVLFTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGA 730 P E V G DP L AYVLFTSGSTG+PKGVEV H AAMNT++ + +G Sbjct 1175 PTEPVAGLVLRAADDPARLDEPAYVLFTSGSTGQPKGVEVGHRAAMNTLDDLVERLGIGP 1234 Query 731 ADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPG 790 DR L ++ L+ D+SV D+FA L +GGA+V+VDE RR+ WA LI + VT LN +P Sbjct 1235 GDRTLGVSALDFDLSVFDLFAPLSAGGAVVLVDEESRREAARWADLIAGHGVTILNCVPA 1294 Query 791 WLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFE 850 LD++L G +SLRAV +GGD V DL RL P RF LGG TETA+H+TI E Sbjct 1295 VLDLVLATGAPLGTSLRAVLLGGDKVGVDLPARLAKAVPGCRFLALGGTTETAIHSTICE 1354 Query 851 VQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPEL 910 V A P+W SVPYG P N RVV G DCPD VAGELW+ G G+ARGYR PE Sbjct 1355 VVGGAAR-PEWRSVPYGTPLRNVRLRVVDALGRDCPDHVAGELWIGGAGVARGYRADPER 1413 Query 911 TAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGV 970 TA+RFV H G WYRTGDLARY DGT+EF+GR DH+VKI G+RVELGE+EAAL LPG+ Sbjct 1414 TADRFVTHGGERWYRTGDLARYLPDGTVEFLGRRDHQVKIRGFRVELGEVEAALAALPGI 1473 Query 971 HAAAATVLPG--GSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPRHVTLLDRIPFTD 1028 A A + G G AV A +IR L ++P HM+P V ++ +P + Sbjct 1474 RAGVAALTAGADGRPATLGAVVAAPPQEDAAAIRAALRSVLPPHMVPDRVVVVAELPLSA 1533 Query 1029 SGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFF 1088 +GKIDR VGALLA E++ S P P + L+R + + ++LG GV D+FF Sbjct 1534 NGKIDRKAVGALLARELDAPRPASRP---PASDLERVILAVWREVLGVGE--CGVLDEFF 1588 Query 1089 ALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREANADRLELVAEVY 1148 ALGGDSVLAT VVA +R LD+ + V +FAA T+A LA+ L E RL+ VA + Sbjct 1589 ALGGDSVLATAVVARLREELDTDEVTVRTLFAAPTVAGLAERLRAAETTPGRLDRVASIA 1648 Query 1149 LEIANMTSADVMAAL 1163 LEIA ++ ++ A L Sbjct 1649 LEIALLSDEEIEARL 1663 >gi|291007147|ref|ZP_06565120.1| non-ribosomal peptide synthase [Saccharopolyspora erythraea NRRL 2338] Length=1164 Score = 903 bits (2334), Expect = 0.0, Method: Compositional matrix adjust. Identities = 584/1169 (50%), Positives = 717/1169 (62%), Gaps = 46/1169 (3%) Query 15 VAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAWSQLV 74 +AEL+ + + ANL GLDSI +M LV RWR+ G+ DFA LA PT+ W++L+ Sbjct 15 LAELVEEEPEDVRASANLFELGLDSIDLMKLVSRWRQAGVQADFAELAHRPTVRDWARLL 74 Query 75 S--AGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVAGHLYVEFDG 132 + T P A D G + + E F LA MQHA WVGR QQLGGVA HLY EFDG Sbjct 75 ADRHETPAQPEHDGAVQDPGSASDAE-FDLALMQHAYWVGRTADQQLGGVAAHLYTEFDG 133 Query 133 ARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDV-VD 191 VDPDRLR+A + L RH MLRV+ DG QR+ G R + V DLR APD V+ Sbjct 134 TGVDPDRLRSALSHLVQRHDMLRVRVGDDGRQRVCAEPGWRG--LVVRDLRD-APDAEVE 190 Query 192 QRLAGIRDAKSHQQLD---GAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLAA 248 Q L RDA SHQ LD G V L+LLPG RTR H+D+DM AADA+SYRILLADLA Sbjct 191 QSLERTRDAMSHQVLDIEAGEVLSTVLSLLPGGRTRFHLDVDMVAADAVSYRILLADLAR 250 Query 249 LY---DGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALPTR-- 303 LY D PP + Y+YREY A +E R A+ WA R+P LP P LP Sbjct 251 LYAEPDAALPP-IRYSYREY-LAARSESRDDAATRAAEH--WAARLPGLPGAPELPMAPQ 306 Query 304 --AGGERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFL 361 A G R R R +L P+ RD L AR G+T A +A AFA VL WS+ RFL Sbjct 307 FPAPG---RPRVVREHVFLPPEERDLLERAARRHGVTLAAAVATAFAEVLGAWSSEPRFL 363 Query 362 LNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPG 421 +N+P+F R +H DVDLLVGDFTSS+LL VDLT A R +A QE L + A H+ + G Sbjct 364 VNVPMFDRSPVHSDVDLLVGDFTSSVLLAVDLTEPLAFADRVRATQERLHADAAHAEHSG 423 Query 422 LSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTE 481 + VLRDL+R G QVLAPVVFTSAL LG+LF V E FG WI+SQGPQVLLDAQ+TE Sbjct 424 VEVLRDLTRSAGRQVLAPVVFTSALNLGELFPGGVRELFGEAVWIVSQGPQVLLDAQITE 483 Query 482 FDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAA 541 G+LVNWDVRE FA GV+ AMF + RLA DAW +P+AQ AVR Sbjct 484 VADGLLVNWDVREREFAEGVVPAMFAAFSSLVERLAGEPDAWRTQVDGMIPSAQAAVRDR 543 Query 542 LNGRTAAPSTEALHDGFFRQAQQQPDAPAVF-ASSGDLSYAQLRDQASAVAAALRAAGLR 600 +N S LH+ FF A +P+APAV LSY +L DQA V AAL G+ Sbjct 544 VNETAGPRSGRLLHEDFFAHAAAEPEAPAVLWGEDRGLSYGELADQALRVGAALLDRGVA 603 Query 601 VGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPC 660 GD V V PK +QV AVLG+LAAGGVY+P+G+DQP RA RI A V G Sbjct 604 PGDPVGVSLPKGADQVVAVLGVLAAGGVYVPVGIDQPATRAARI--------AQVAGFQV 655 Query 661 QV---RVPVPTLLLADVLAAAPAEFVPGPSDPTALAYVLFTSGSTGEPKGVEVAHDAAMN 717 Q+ R L L D A P P D LAYVLFTSGSTGEPKGVEV H AAMN Sbjct 656 QITADRDADGALALEDAFAHPPLA-APVTQDEEQLAYVLFTSGSTGEPKGVEVPHRAAMN 714 Query 718 TVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLI 777 T+E R F LG DR LA++ L+ D+SV D+FA L +GGA+VVV E +RRD WA L+ Sbjct 715 TIEDLRRRFGLGPGDRTLAVSALDFDLSVFDVFAPLSAGGAVVVVAEEERRDAHRWAELV 774 Query 778 DTYEVTALNFMPGWLDMLLEVGGGR--LSSLRAVAVGGDWVRPDLARRLQVQAPSARFAG 835 ++V+ LN +P LD+LL G L+SLR V +GGD V DL RL AP RF Sbjct 775 RGHQVSVLNCVPPLLDVLLRAVGESQDLASLRVVLLGGDRVGVDLPGRLSAAAPGCRFIA 834 Query 836 LGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWV 895 LGG TETA+H+TI EV +LP D SVPYG P N A RVV G DCPDWVAGELW+ Sbjct 835 LGGTTETAIHSTIHEVPAGGSLPADCQSVPYGTPLRNVALRVVDALGRDCPDWVAGELWI 894 Query 896 SGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRV 955 G G+ARGYR P+ TA+RFVE GR WYRTGDLARY G +EF+GR D +VKI G+RV Sbjct 895 GGDGVARGYRADPDRTADRFVESGGRRWYRTGDLARYRPGGIVEFLGRHDDQVKIRGFRV 954 Query 956 ELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIP 1015 ELGE+EAAL V AA A S VL AAV D G +S+R+++ DL+P HM+P Sbjct 955 ELGEVEAALLDDSRVRAAVAVAHGESSPVLGAAVVTD--GTDVDSVRERVRDLLPPHMVP 1012 Query 1016 RHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILG 1075 + +++IP T +GK+DR V + VERS + APRT L+RAL + A++LG Sbjct 1013 DRLVAVEQIPLTGNGKVDRRAV----RSTVERSVRNATDRIAPRTDLERALAIVWAEVLG 1068 Query 1076 RAN-DAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGR 1134 + ++V V DDFFA GGDS+LAT++V G+R LD+ ++ V + + TIA LA + Sbjct 1069 IDDLESVSVDDDFFAAGGDSLLATKLVTGVRDALDTAAVSVRMLLSQPTIAGLADRMGAA 1128 Query 1135 EANADRLELVAEVYLEIANMTSADVMAAL 1163 E +RLE A ++ EIA ++ +V+A L Sbjct 1129 EQVPERLERAAALFCEIAALSEEEVVAQL 1157 >gi|340795784|ref|YP_004761247.1| nonribosomal peptide synthetase [Corynebacterium variabile DSM 44702] gi|340535694|gb|AEK38174.1| nonribosomal peptide synthetase [Corynebacterium variabile DSM 44702] Length=1186 Score = 879 bits (2270), Expect = 0.0, Method: Compositional matrix adjust. Identities = 544/1178 (47%), Positives = 690/1178 (59%), Gaps = 50/1178 (4%) Query 10 IIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRR-KGIAVDFATLAATPTIE 68 ++R A+ LG + NL+ GLDS+ M+ + R R G+ V FA A +++ Sbjct 12 LMRQLAADSLGATVAEIEDSENLISLGLDSVAMIGISARVREATGLQVPFAAFARDASVD 71 Query 69 AWSQLVSAGTGVAPTAVAAPGD---AGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVAGH 125 W+++V+ P AA D AG E PFPLA MQHA WVGR + Q LGGVA H Sbjct 72 GWTRIVAEAAAEGPADAAAATDLSPAGSPLEAAPFPLATMQHAYWVGRTEGQVLGGVAAH 131 Query 126 LYVEFDGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHV 185 LY EFDG VDPDRL AA RL RH LR + LP+GTQ + A G F +V DLR Sbjct 132 LYAEFDGPAVDPDRLSAAVDRLTDRHTSLRTRVLPNGTQEVLDAPGKPVF--TVTDLRDR 189 Query 186 APDVVDQRLAGIRDAKSHQQLD---GAVFELALTLLPGERTRLHVDLDMQAADAMSYRIL 242 ++Q L IR+ K+HQ LD G V +++LTLLPG+R+RLH+D+DM AADAMSYR + Sbjct 190 NTTEIEQDLESIRETKTHQLLDLAAGQVIDISLTLLPGDRSRLHLDVDMIAADAMSYRTI 249 Query 243 LADLAALYDGREP-PA-LGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPAL 300 LADLAA Y +EP PA L Y YR Y + T + + WW +R+ P+ P+L Sbjct 250 LADLAAFYREQEPSPAILDYQYRTY---LHEHGTSMSAAAEKEGAWWRERVTDYPEAPSL 306 Query 301 PTRAGGER-DRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSR 359 P + D RS R L P + L+ RA A G+TPAM LA F++ LARWS+ R Sbjct 307 PLVPEQKMADPHRSVRLDVLLSPDQKARLYDRAHAHGVTPAMVLATVFSDTLARWSSHQR 366 Query 360 FLLNLPLFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAY 419 FLLNLPLF R+ LH V LVGDF++SLLLDVD+ ++ R +++Q L A HSA+ Sbjct 367 FLLNLPLFDREPLHEHVAGLVGDFSNSLLLDVDVDAGKSFLERVRSMQSTLHETAEHSAF 426 Query 420 PGLSVLRDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQV 479 GL VLR+L + G V APVV+TS L LG+LF VTE+FG P WIISQGPQV+LDAQV Sbjct 427 RGLDVLRELGHNAGAPVTAPVVYTSGLDLGELFAEAVTEEFGEPVWIISQGPQVVLDAQV 486 Query 480 TEFDGGVLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDA---WDAPSPSALPAAQR 536 E GG+L+NWDVR F GVI+AMF L L A D+ W P ALP +QR Sbjct 487 AEIKGGILLNWDVRRDAFPEGVIEAMFAAYRGLLEELLARDEMASDWTLPHTIALPESQR 546 Query 537 AVRAALNGRTAAP----STEALHDGFFRQAQQQPDAPAVF-------------ASSGDLS 579 VR + A + LHD FF +A PD PAVF A +G L+ Sbjct 547 QVRERIEKEAAEAGAAITPRTLHDSFFDRAATDPDRPAVFWGTGENGRGTGIDAKTGQLT 606 Query 580 YAQLRDQASAVAAALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRD 639 Y +L ++A VA AL+A G++ GDTVAV K Q+ VLGILA G +LPIG DQP Sbjct 607 YGELAERALRVAGALQAKGVKAGDTVAVHTAKGHRQIPVVLGILALGANFLPIGADQPEA 666 Query 640 RAERILA-TGSVNLALVCGPPCQVRVP--VPTLLLADVLAAAPAEFVPGPSDPTALAYVL 696 R IL +G+V + +P V L L L + + DP A+AYVL Sbjct 667 RRTVILERSGAVAIVTDKHGKRLGSLPEGVTKLDLQAALTSLDSLTERATVDPDAVAYVL 726 Query 697 FTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSG 756 FTSGSTGEPKGVEV H AA NT++ F L DR L ++ LE D SV+D F AL G Sbjct 727 FTSGSTGEPKGVEVPHRAAANTIDAVAEVFHLDENDRTLNISVLEFDPSVMDFFGALHWG 786 Query 757 GAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVGG-GRLSSLRAVAVGGDW 815 G+I+ V+ + ++ WA+L Y TAL P L MLL+V +L SL AV +GGDW Sbjct 787 GSIIAVEADEAKEALVWAQLAQRYGATALTVAPSILGMLLDVATVEQLQSLHAVMLGGDW 846 Query 816 VRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNAC 875 V DL RL AP ARFAGLGGATE A+H T+ EV +P W++VPYG P PN C Sbjct 847 VTVDLPTRLHELAPQARFAGLGGATEVAIHCTVCEV--TGPVPEQWSAVPYGTPLPNFRC 904 Query 876 RVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHD 935 RVV +G D PD+VAGELW+ G +A GYR PE TAE+FVE DG WYRTGDLA Y D Sbjct 905 RVVNAAGQDAPDFVAGELWIGGPSVADGYRNDPERTAEKFVEEDGTRWYRTGDLAFYHPD 964 Query 936 GTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVC---VD 992 G LEF+GRADH+V++ GYR+ELGE+E AL+ +PG A A V L AAV Sbjct 965 GMLEFLGRADHQVQVKGYRIELGEVETALRTVPGASEAVAFVTDDSPKRLFAAVTPVEST 1024 Query 993 DAGVTAES-IRQQLADLVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDR 1051 DA AE+ +R+ + LVPA+M+P V + + P T +GK DR + A +AA + Sbjct 1025 DAEALAETDLREAVGALVPAYMVPERVEVFETFPLTRNGKTDRKAIAAEVAARGAAAAAE 1084 Query 1052 SAPYAAPRTVLQRALRRIVADILGRANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSP 1111 A P L+ AL IV ++L + V V DFF+ GGDSVLAT+ A IR L Sbjct 1085 GNAPATP---LEVALTVIVNEVL--PEELVAVDRDFFSAGGDSVLATRATAHIREHLAVQ 1139 Query 1112 SLMVADMFAARTIAALAQLLTGREANADRLELVAEVYL 1149 +L+ AD F ARTI LA+LL +E AD ++ YL Sbjct 1140 TLVSADFFQARTIRDLAKLLRKQEDTADGMDEAVAAYL 1177 >gi|111223561|ref|YP_714355.1| putative non-ribosomal peptide synthase [Frankia alni ACN14a] gi|111151093|emb|CAJ62802.1| Putative non-ribosomal peptide synthase [Frankia alni ACN14a] Length=1862 Score = 855 bits (2208), Expect = 0.0, Method: Compositional matrix adjust. Identities = 597/1361 (44%), Positives = 740/1361 (55%), Gaps = 204/1361 (14%) Query 9 EIIRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIE 68 E +R AEL+ L NL +GL+SI ++ VG+WRR GI V+FA LA PT++ Sbjct 473 ERLRCIAAELVEEDPADLADDDNLFERGLESIALIRAVGQWRRAGIEVNFAELAENPTVD 532 Query 69 AWSQLVSAGTGVA-----------------PTAVAAPG-------------DAGLSQ-EG 97 W L+++ A PT VA P +AG + +G Sbjct 533 GWFTLLASRQPAAARQPGAEGPAGEPAPAGPTTVATPHAGAEANGVEVAGVEAGEGEMDG 592 Query 98 EPFPLAPMQHAMWVGRHDHQQLGGVAGHLYVEFDGARVDPDRLRAAATRLALRHPMLRVQ 157 FPLA MQHA W+GR D Q GGVA HLY EFDG+ ++P RL AA RL RH LR + Sbjct 593 AEFPLAHMQHAYWIGRGDGQTYGGVAAHLYTEFDGSGLEPARLTAAIERLVERHEALRTR 652 Query 158 FLPDGTQRIPPAAGSRDFPISVADLRHVAPDVVDQRLAGIRDAKSHQQLD---GAVFELA 214 +G Q + +G R ++V DLR + D V RLA +RD SHQ LD G VF A Sbjct 653 ITDNGAQIVEARSGWRG--LTVHDLRELDADEVTARLAAVRDRLSHQMLDIERGEVFSTA 710 Query 215 LTLLPGERTRLHVDLDMQAADAMSYRILLADLAALY---DGREP-PALGYTYREYRQAIE 270 L+L P TR H+D+DM AADA+SYR+LLADLA Y D P PA +TYR YR + Sbjct 711 LSLRPDGTTRFHLDVDMVAADAVSYRVLLADLAEEYGRPDEVAPAPAPAFTYRRYRAERD 770 Query 271 AEETLPQPVRDADRDWWAQRIPQLPDPPALPTR-----------------AGGERDRRRS 313 + W R+P LP P LP AG R Sbjct 771 VDARAAAEQARRA---WLDRLPGLPGAPQLPLAPHLPLAPQLPLAPQPGAAGAPSGAPRV 827 Query 314 TRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLNLPLFSRQALH 373 +RR L P R AL A G+TPAM +A AFA VL WSA RFLLN+PLF R+ +H Sbjct 828 SRRHFRLPPSARAALGRAAHRHGLTPAMAVATAFAEVLGGWSAQPRFLLNVPLFDREPIH 887 Query 374 PDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLSVLRDLSRHRG 433 PDV+ +VGDFTSS+LL+VDLT + RA+ +Q L + A H+ Y G+ VLRDL R RG Sbjct 888 PDVNRIVGDFTSSVLLEVDLTDSIPFVERARRLQARLHADAAHADYSGVEVLRDLGRLRG 947 Query 434 TQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGGVLVNWDVR 493 VLAPVVFTSALGLG+LF V +FG P WIISQGPQVLLDAQVTE DGG+LVNWDVR Sbjct 948 EPVLAPVVFTSALGLGELFDASVRREFGEPEWIISQGPQVLLDAQVTELDGGMLVNWDVR 1007 Query 494 EGVFAPGVIDAMFT---HQVDELLRLAAGDD---------AWDAPSPSALPAAQRAVRAA 541 E FAPGV+DAMF+ V L L D AWD P L A+ RAVRA Sbjct 1008 EDTFAPGVVDAMFSVFERLVRGLADLGPTDGSAVTGAAAVAWDQPVDGLLDASTRAVRAR 1067 Query 542 LNGRTAAPSTEALHDGFFRQAQQQPDAPAVF--ASSG--------DLSYAQLRDQASAVA 591 +N ST LH+GFF A+ P+APA+ A +G LSY +L QA+AVA Sbjct 1068 VNTIAGPLSTRLLHEGFFAAARDDPNAPALVWDAPAGGAQSPVRRSLSYGELAGQATAVA 1127 Query 592 AALRAAGLRVGDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVN 651 AL A +R GD V V PK EQV A+LG+LAAG Y+PIGV+QP R RI+ T + Sbjct 1128 GALVARSVRPGDLVGVSLPKGPEQVVAILGVLAAGATYVPIGVEQPAARVARIVDTAGLR 1187 Query 652 LALVC--------------------------GP--PCQVR-VPVPTLLLADVLAAAPAEF 682 + GP P VR + + L A A+ A Sbjct 1188 TVITVPSTASSADRASSADRASSADGSAAPSGPDWPVGVRPLSLDDALAAGAATASGALT 1247 Query 683 VPGPSDPTAL---AYVLFTSGSTGEPKGVEVAHDAAMNTVETFIRHFELGAADRWLALAT 739 + DP L AYVLFTSGSTG+PKGVEV+H AAMNT++ LG DR L ++ Sbjct 1248 LSAADDPARLDEPAYVLFTSGSTGQPKGVEVSHRAAMNTIDDLADRLGLGPGDRTLGVSA 1307 Query 740 LECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARLIDTYEVTALNFMPGWLDMLLEVG 799 L+ D+SV D+FA L SGGA+VVVDE RR+ WA LI + VT LN +P LD++L G Sbjct 1308 LDFDLSVFDVFAPLSSGGAVVVVDEESRREATRWAELIAAHRVTILNCVPAVLDLVLATG 1367 Query 800 GGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGLGGATETAVHATIFEVQDAANLPP 859 +SLRAV +GGD V DL RL+ RF GLGG TETA+H+T+ EV +PP Sbjct 1368 VPLGASLRAVLLGGDRVGVDLPGRLEAAVAGCRFLGLGGTTETAIHSTVCEVVGGGPVPP 1427 Query 860 DWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVSGRGIARGYRGRPELTAERFVEHD 919 W SVPYG P RVV G DCPD V GELW+ G G+ARGYRG PE TA+RFV H Sbjct 1428 AWRSVPYGTPLRGVRLRVVDGLGRDCPDHVVGELWIGGAGVARGYRGDPERTADRFVRHA 1487 Query 920 GRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVELGEIEAALQRLPGVHAAAATVLP 979 G WYRTGDLARY DGT+EF+GR DH+VKI G+RVELGEIEAAL +PGV A A L Sbjct 1488 GERWYRTGDLARYLLDGTVEFLGRRDHQVKIRGFRVELGEIEAALASVPGVRAGVAA-LT 1546 Query 980 GGSD----VLAAAVCV-------------------DDAGVTAESIRQQLAD--------- 1007 GG+D L A V + D A T + + LAD Sbjct 1547 GGADGHPSALGAVVVLTAAEGPPRPADQTRPADQTDPADQTDPADQTDLADQTDLATVRA 1606 Query 1008 ----LVPAHMIPRHVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYA-APRTVL 1062 ++P HM+P V + +P + +GKIDR VGALL ER D + P A AP + L Sbjct 1607 GLRAVLPPHMVPDRVVAVAELPLSANGKIDRKAVGALL----ERDLDGTRPAATAPTSDL 1662 Query 1063 QRAL----RRIV-------------------------------------ADILGRAND-- 1079 +R + R I+ AD +G A + Sbjct 1663 ERVILSVWREILPRDTVGVTDTVRAADTVRAADTVRAADTVRAADTVRAADTVGAAGEFG 1722 Query 1080 ---AVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREA 1136 A GV D+FFALGGDSVLAT +VA +R LD+ + V +F A T+AALAQ + E+ Sbjct 1723 VSGAFGVTDEFFALGGDSVLATAMVARLRDELDTGEVTVRMLFGAPTVAALAQAMRAAES 1782 Query 1137 NADRLELVAEVYLEIANMTSADVMA-ALDPIEQPAQPAFKP 1176 RL+ VA + EIA ++ ++ A LDP+ P PA P Sbjct 1783 TPGRLDRVAAIIWEIACLSDDEIEARLLDPVGPPG-PADTP 1822 >gi|343925522|ref|ZP_08765041.1| putative non-ribosomal peptide synthetase [Gordonia alkanivorans NBRC 16433] gi|343764614|dbj|GAA11967.1| putative non-ribosomal peptide synthetase [Gordonia alkanivorans NBRC 16433] Length=1151 Score = 843 bits (2179), Expect = 0.0, Method: Compositional matrix adjust. Identities = 536/1167 (46%), Positives = 695/1167 (60%), Gaps = 52/1167 (4%) Query 11 IRAEVAELLGVRADALHPGANLVGQGLDSIRMMSLVGRWRRKGIAVDFATLAATPTIEAW 70 IRA+VA LGV ++L P +L+ QGLDS+RMM L G WR++GI +DFA LAA+PT++AW Sbjct 20 IRAQVAAALGVTPESLDPTGDLIAQGLDSLRMMRLAGTWRKRGIDIDFARLAASPTLDAW 79 Query 71 SQLVSAGTGVAPTAVAAPGDAGLSQEGEPFPLAPMQHAMWVGRHDHQQLGGVAGHLYVEF 130 + L+ G A+P + + PFPLAPMQHA W+GR D G VA HLY+EF Sbjct 80 TALL-GGPSTPAEMSASPENVDPTA---PFPLAPMQHAYWIGRSDSHAFGNVAAHLYIEF 135 Query 131 DGARVDPDRLRAAATRLALRHPMLRVQFLPDGTQRIPPAAGSRDFPISVADLRHVAPDVV 190 DG +DPDR A L RHPMLRV+ LPDGTQ + PA I+V DLR + ++V Sbjct 136 DGHGLDPDRFTTAMGELMERHPMLRVRVLPDGTQVVGPAHPD---AIAVHDLRSQSAEMV 192 Query 191 DQRLAGIRDAKSHQQL---DGAVFELALTLLPGERTRLHVDLDMQAADAMSYRILLADLA 247 ++ LA R +H+ L +GAV L+LLP TR+H+D+DM AADAMSYR+L+ D A Sbjct 193 EKILAETRSHGTHRTLPVEEGAVIRAELSLLPDGSTRVHLDVDMIAADAMSYRVLVDDFA 252 Query 248 ALYDGREPPALGYTYREYRQAIEAEETLPQPVRDADRDWWAQRIPQLPDPPALP--TRAG 305 LY G P LG T+ I A+ T + +RD D WW +RIP LP PP LP RA Sbjct 253 RLYRGETLPELGVTF----ATITADRT-SREIRDEDLAWWRERIPHLPGPPELPLDDRAA 307 Query 306 GERDRRRSTRRWHWLDPQTRDALFARARARGITPAMTLAAAFANVLARWSASSRFLLNLP 365 RS R H + L A RG+TPA +AA FA + +A+SRFLL +P Sbjct 308 RGEVEPRSVRLHHSVSASEWKRLEEHAHRRGVTPAAAVAAVFAEAVGTHAANSRFLLTVP 367 Query 366 LFSRQALHPDVDLLVGDFTSSLLLDVDLTGARTAAARAQAVQEALRSAAGHSAYPGLSVL 425 LF R +H DV+ +VGDFTSS+L++ DL+ + T A RA+ ++ A+ AA H + GL VL Sbjct 368 LFDRPRIHADVERVVGDFTSSILVEADLSESATLAERARQMRSAMHDAAAHGSMSGLDVL 427 Query 426 RDLSRHRGTQVLAPVVFTSALGLGDLFCPDVTEQFGTPGWIISQGPQVLLDAQVTEFDGG 485 R+L R RG V++PVVFTSALGLGDLF P T+ G P WI+SQGPQVLLDAQVTE GG Sbjct 428 RELGRARGESVISPVVFTSALGLGDLFSPQATDVLGDPAWIVSQGPQVLLDAQVTEIAGG 487 Query 486 VLVNWDVREGVFAPGVIDAMFTHQVDELLRLAAGDDAWDAPSPSALPAAQRAVRAALNGR 545 +L+NWDVR AMF + V L L G+ WD P+P + RA R L+ Sbjct 488 LLLNWDVRVSDLDESTARAMFDYYVRLLGLLVDGE--WDVPAPDPVADDVRAQR--LSVE 543 Query 546 TAAPSTE----ALHDGFFRQAQQQPDAPAVFASSGDLSYAQLRDQASAVAAALRAAGLRV 601 P T+ LH F +A Q+P PAV S ++ +L D+A VA AL AAG+ Sbjct 544 RPLPDTDTFDGTLHGTIFGRAAQRPTTPAVTTDSRTWTHGELTDEALRVAGALAAAGVCT 603 Query 602 GDTVAVLGPKTGEQVAAVLGILAAGGVYLPIGVDQPRDRAERILATGSVNLALVCGPPCQ 661 GDTV V PK G+QV A L +LA G Y+PI QP R +RI++ L Sbjct 604 GDTVVVNLPKGGDQVVAALAVLAVGAAYVPIAPTQPATRRDRIVSIAGPRAVLTADVDAW 663 Query 662 VRVPVPTLLLADVLAAAPAEFVPGPSDPT-----ALAYVLFTSGSTGEPKGVEVAHDAAM 716 PT++ D A P DP LAY+LFTSGSTG PKGV+V H AA+ Sbjct 664 TESNGPTVIDLD------AARTSAPVDPVEVTGEELAYILFTSGSTGLPKGVQVPHRAAV 717 Query 717 NTVETFIRHFELGAADRWLALATLECDMSVLDIFAALRSGGAIVVVDEAQRRDPDAWARL 776 T+ + + + A DR L +++LE D+SV DIF L GGA+VV + +R D W RL Sbjct 718 ATISDLVDRYSIDARDRSLQVSSLEFDLSVFDIFGLLAVGGAVVVPGDDERTKVDDWVRL 777 Query 777 IDTYEVTALNFMPGWLDMLLEVGGGRLSSLRAVAVGGDWVRPDLARRLQVQAPSARFAGL 836 + + V+ LN +P L M+L++ S+R + +GGD V L R+ Q P R AGL Sbjct 778 LAEHSVSVLNCVPSILGMILDI-DSLPPSMRMIIMGGDKVDVSLLERVATQLPDCRVAGL 836 Query 837 GGATETAVHATIFEVQDAANLPPDWASVPYGVPFPNNACRVVADSGDDCPDWVAGELWVS 896 GG TETA+H+TI E D +P A VPYGVP CRVV ++G D PD V GELW+ Sbjct 837 GGTTETAIHSTICEADD---VPAGMAFVPYGVPLRGVRCRVVDETGRDRPDLVPGELWIG 893 Query 897 GRGIARGYRGRPELTAERFVEHDGRTWYRTGDLARYWHDGTLEFVGRADHRVKISGYRVE 956 G G+A GYRG PE TA+RFV HDG WYRTGDLARY G L+F+GRADH VK+ GYRVE Sbjct 894 GAGVADGYRGDPERTADRFVHHDGEKWYRTGDLARYLPGGFLDFLGRADHMVKVRGYRVE 953 Query 957 LGEIEAALQRLPGVHAAAATVLPGGSDVLAAAVCVDDAGVTAESIRQQLADLVPAHMIPR 1016 LGE+EA L L V A+A G D L AAV + +IR +L++ +P HMIPR Sbjct 954 LGEVEAGLLALDEV--ASAVAWSDGRD-LQAAVVAAGTVIDENAIRDRLSESLPPHMIPR 1010 Query 1017 HVTLLDRIPFTDSGKIDRAEVGALLAAEVERSGDRSAPYAAPRTVLQRALRRIVADILGR 1076 VT+LD +P T +GK DR + AL+ + + APRT L+ AL I +++L Sbjct 1011 TVTVLDALPLTANGKYDRKALAALV-----DTAEGGPQVVAPRTPLEEALVVIFSEVL-- 1063 Query 1077 ANDAVGVHDDFFALGGDSVLATQVVAGIRRWLDSPSLMVADMFAARTIAALAQLLTGREA 1136 +GV +DF +LGGDSV AT++VA R WLD+P L VAD+F RTIA LA+ LT E Sbjct 1064 PVRPIGVTEDFISLGGDSVQATRLVALSRTWLDAPRLSVADIFGHRTIAGLAERLTALEG 1123 Query 1137 NADRLELVAEVYLEIANMTSADVMAAL 1163 R+E VA + L++ ++ V A L Sbjct 1124 T--RVERVAAILLDVVALSDQQVDAEL 1148 Lambda K H 0.321 0.136 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 3643966848574 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40