BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2384 Length=565 Score E Sequences producing significant alignments: (Bits) Value gi|15609521|ref|NP_216900.1| bifunctional salicyl-AMP ligase/sal... 1125 0.0 gi|289443906|ref|ZP_06433650.1| bifunctional salicyl-AMP ligase/... 1125 0.0 gi|340627395|ref|YP_004745847.1| bifunctional salicyl-AMP ligase... 1124 0.0 gi|254774733|ref|ZP_05216249.1| 2,3-dihydroxybenzoate-AMP ligase... 832 0.0 gi|296170577|ref|ZP_06852161.1| mycobactin-specific salicyl-AMP ... 830 0.0 gi|336458161|gb|EGO37144.1| peptide arylation enzyme [Mycobacter... 828 0.0 gi|118462251|ref|YP_881227.1| 2,3-dihydroxybenzoate-AMP ligase [... 827 0.0 gi|254821622|ref|ZP_05226623.1| 2,3-dihydroxybenzoate-AMP ligase... 827 0.0 gi|342857514|ref|ZP_08714170.1| 2,3-dihydroxybenzoate-AMP ligase... 810 0.0 gi|183983678|ref|YP_001851969.1| bifunctional enzyme MbtA: salic... 788 0.0 gi|118618913|ref|YP_907245.1| bifunctional enzyme MbtA: salicyl-... 782 0.0 gi|240169929|ref|ZP_04748588.1| bifunctional enzyme MbtA: salicy... 759 0.0 gi|118468444|ref|YP_888788.1| 2,3-dihydroxybenzoate-AMP ligase [... 754 0.0 gi|289758509|ref|ZP_06517887.1| salicyl-AMP ligase + salicyl-S-a... 707 0.0 gi|126436060|ref|YP_001071751.1| AMP-dependent synthetase and li... 705 0.0 gi|108800437|ref|YP_640634.1| AMP-dependent synthetase and ligas... 704 0.0 gi|315443738|ref|YP_004076617.1| peptide arylation enzyme [Mycob... 681 0.0 gi|145223278|ref|YP_001133956.1| AMP-dependent synthetase and li... 681 0.0 gi|120404808|ref|YP_954637.1| AMP-dependent synthetase and ligas... 674 0.0 gi|333990168|ref|YP_004522782.1| bifunctional enzyme MbtA: salic... 663 0.0 gi|169629333|ref|YP_001702982.1| bifunctional salicyl-AMP ligase... 660 0.0 gi|226361743|ref|YP_002779521.1| 2,3-dihydroxybenzoate-AMP ligas... 565 9e-159 gi|54022587|ref|YP_116829.1| putative hydroxybenzoate-AMP ligase... 563 3e-158 gi|134099240|ref|YP_001104901.1| 2,3-dihydroxybenzoate-AMP ligas... 523 4e-146 gi|288922802|ref|ZP_06416969.1| AMP-dependent synthetase and lig... 509 6e-142 gi|269124635|ref|YP_003298005.1| AMP-dependent synthetase and li... 508 1e-141 gi|115374171|ref|ZP_01461458.1| 2,3-dihydroxybenzoate-AMP ligase... 498 8e-139 gi|111223560|ref|YP_714354.1| 2,3-dihydroxybenzoate-AMP ligase [... 498 9e-139 gi|326383365|ref|ZP_08205052.1| AMP-dependent synthetase and lig... 497 2e-138 gi|11127897|gb|AAG31128.1|AF299336_5 MxcE [Stigmatella aurantiac... 496 3e-138 gi|338534899|ref|YP_004668233.1| 2,3-dihydroxybenzoate-AMP ligas... 496 4e-138 gi|317506252|ref|ZP_07964071.1| 2,3-dihydroxybenzoate-AMP ligase... 494 1e-137 gi|262200633|ref|YP_003271841.1| AMP-dependent synthetase and li... 493 3e-137 gi|312198336|ref|YP_004018397.1| AMP-dependent synthetase and li... 493 4e-137 gi|41408276|ref|NP_961112.1| MbtA [Mycobacterium avium subsp. pa... 492 7e-137 gi|229017675|ref|ZP_04174566.1| 2,3-dihydroxybenzoate-AMP ligase... 490 2e-136 gi|108757791|ref|YP_631832.1| 2,3-dihydroxybenzoate-AMP ligase [... 490 3e-136 gi|228945975|ref|ZP_04108317.1| 2,3-dihydroxybenzoate-AMP ligase... 489 6e-136 gi|196043674|ref|ZP_03110912.1| 2,3-dihydroxybenzoate-AMP ligase... 488 1e-135 gi|229030073|ref|ZP_04186137.1| 2,3-dihydroxybenzoate-AMP ligase... 488 1e-135 gi|228914959|ref|ZP_04078564.1| 2,3-dihydroxybenzoate-AMP ligase... 487 2e-135 gi|301053889|ref|YP_003792100.1| 2,3-dihydroxybenzoate-AMP ligas... 487 2e-135 gi|229091345|ref|ZP_04222560.1| 2,3-dihydroxybenzoate-AMP ligase... 487 2e-135 gi|229060018|ref|ZP_04197389.1| 2,3-dihydroxybenzoate-AMP ligase... 486 4e-135 gi|30262375|ref|NP_844752.1| 2,3-dihydroxybenzoate-AMP ligase [B... 486 5e-135 gi|81681119|emb|CAJ34366.1| putative 3-hydroxy-quinaldate-AMP-Li... 486 5e-135 gi|72162270|ref|YP_289927.1| 2,3-dihydroxybenzoate-AMP ligase [T... 486 6e-135 gi|167639615|ref|ZP_02397885.1| 2,3-dihydroxybenzoate-AMP ligase... 486 6e-135 gi|52143109|ref|YP_083720.1| 2,3-dihydroxybenzoate-AMP ligase [B... 486 6e-135 gi|228965341|ref|ZP_04126433.1| 2,3-dihydroxybenzoate-AMP ligase... 485 7e-135 >gi|15609521|ref|NP_216900.1| bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase [Mycobacterium tuberculosis H37Rv] gi|15841896|ref|NP_336933.1| 2,3-dihydroxybenzoate-AMP ligase [Mycobacterium tuberculosis CDC1551] gi|31793561|ref|NP_856054.1| bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase [Mycobacterium bovis AF2122/97] 68 more sequence titles Length=565 Score = 1125 bits (2911), Expect = 0.0, Method: Compositional matrix adjust. Identities = 565/565 (100%), Positives = 565/565 (100%), Gaps = 0/565 (0%) Query 1 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA 60 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA Sbjct 1 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA 60 Query 61 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA 120 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA Sbjct 61 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA 120 Query 121 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP 180 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP Sbjct 121 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP 180 Query 181 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL 240 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL Sbjct 181 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL 240 Query 241 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA 300 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA Sbjct 241 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA 300 Query 301 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL 360 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL Sbjct 301 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL 360 Query 361 NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER 420 NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER Sbjct 361 NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER 420 Query 421 DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS 480 DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS Sbjct 421 DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS 480 Query 481 AAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPI 540 AAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPI Sbjct 481 AAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPI 540 Query 541 GKIDKRAIVRQLGIATGPVTTQRCH 565 GKIDKRAIVRQLGIATGPVTTQRCH Sbjct 541 GKIDKRAIVRQLGIATGPVTTQRCH 565 >gi|289443906|ref|ZP_06433650.1| bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase mbtA [Mycobacterium tuberculosis T46] gi|289570528|ref|ZP_06450755.1| bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase mbtA [Mycobacterium tuberculosis T17] gi|289416825|gb|EFD14065.1| bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase mbtA [Mycobacterium tuberculosis T46] gi|289544282|gb|EFD47930.1| bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase mbtA [Mycobacterium tuberculosis T17] Length=565 Score = 1125 bits (2909), Expect = 0.0, Method: Compositional matrix adjust. Identities = 564/565 (99%), Positives = 565/565 (100%), Gaps = 0/565 (0%) Query 1 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA 60 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA Sbjct 1 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA 60 Query 61 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA 120 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA Sbjct 61 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA 120 Query 121 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP 180 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP Sbjct 121 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP 180 Query 181 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL 240 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL Sbjct 181 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL 240 Query 241 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA 300 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA Sbjct 241 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA 300 Query 301 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL 360 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL Sbjct 301 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL 360 Query 361 NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER 420 NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER Sbjct 361 NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER 420 Query 421 DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS 480 DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS Sbjct 421 DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS 480 Query 481 AAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPI 540 AAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDRRGVA+HTRPDQLVAMPALPTTPI Sbjct 481 AAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDRRGVASHTRPDQLVAMPALPTTPI 540 Query 541 GKIDKRAIVRQLGIATGPVTTQRCH 565 GKIDKRAIVRQLGIATGPVTTQRCH Sbjct 541 GKIDKRAIVRQLGIATGPVTTQRCH 565 >gi|340627395|ref|YP_004745847.1| bifunctional salicyl-AMP ligase/salicyl-S-ArCP synthetase [Mycobacterium canettii CIPT 140010059] gi|340005585|emb|CCC44747.1| bifunctional enzyme MBTA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase [Mycobacterium canettii CIPT 140010059] Length=565 Score = 1124 bits (2908), Expect = 0.0, Method: Compositional matrix adjust. Identities = 564/565 (99%), Positives = 565/565 (100%), Gaps = 0/565 (0%) Query 1 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA 60 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA Sbjct 1 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA 60 Query 61 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA 120 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA Sbjct 61 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA 120 Query 121 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP 180 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP Sbjct 121 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP 180 Query 181 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL 240 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL Sbjct 181 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL 240 Query 241 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA 300 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA Sbjct 241 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA 300 Query 301 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL 360 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL Sbjct 301 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL 360 Query 361 NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER 420 NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER Sbjct 361 NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER 420 Query 421 DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS 480 DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS Sbjct 421 DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS 480 Query 481 AAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPI 540 AAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLD+RGVAAHTRPDQLVAMPALPTTPI Sbjct 481 AAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDQRGVAAHTRPDQLVAMPALPTTPI 540 Query 541 GKIDKRAIVRQLGIATGPVTTQRCH 565 GKIDKRAIVRQLGIATGPVTTQRCH Sbjct 541 GKIDKRAIVRQLGIATGPVTTQRCH 565 >gi|254774733|ref|ZP_05216249.1| 2,3-dihydroxybenzoate-AMP ligase [Mycobacterium avium subsp. avium ATCC 25291] Length=545 Score = 832 bits (2148), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/542 (81%), Positives = 471/542 (87%), Gaps = 9/542 (1%) Query 13 PDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLS 72 P G L GFVPFPADRAA+YRAAGYW+GRTLDT+L+DAAR+WPDR AV DA G G S Sbjct 8 PAGVLDGFVPFPADRAAAYRAAGYWAGRTLDTILTDAARQWPDRTAVRDA---VGGTGFS 64 Query 73 YAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAA 132 YA+LD +A+RA+ L LGI PGDRVLLQLPN CQFAVALF LLRAGA+PVMCLPGHRAA Sbjct 65 YADLDDQANRASGGLRALGIAPGDRVLLQLPNSCQFAVALFGLLRAGAVPVMCLPGHRAA 124 Query 133 ELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQ 192 ELGHFAAVSAATGL++AD A+GFDYR MA L+ ++PTLRHVIVDGDPGPF SWAQLC + Sbjct 125 ELGHFAAVSAATGLLIADTAAGFDYRTMALGLIEENPTLRHVIVDGDPGPFTSWAQLCER 184 Query 193 AGTGSPAPP--ADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYL 250 A P PP ADPGSPALLLVSGGTTG PKLIPRTHDDYVFNATASA LCRL+ DDVYL Sbjct 185 A----PGPPSSADPGSPALLLVSGGTTGTPKLIPRTHDDYVFNATASAELCRLTCDDVYL 240 Query 251 VVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWA 310 VL+AGHNFPLACPGLLGAMTVGAT VF DPSPEAAFAAI+RHGVTVTALVPALAKLWA Sbjct 241 AVLSAGHNFPLACPGLLGAMTVGATTVFGTDPSPEAAFAAIDRHGVTVTALVPALAKLWA 300 Query 311 QSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPE 370 Q+CEWEPVTPK+LRLLQVGG+KLEPEDAR VRTALTPGLQQVFGMAEGLLN+TR DPPE Sbjct 301 QACEWEPVTPKTLRLLQVGGAKLEPEDARLVRTALTPGLQQVFGMAEGLLNYTRPDDPPE 360 Query 371 VVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDG 430 + EHTQGRPL ADELR+VNA GEPV PGEEGELLVRGPYT NGYF AERDNERCFD G Sbjct 361 LTEHTQGRPLSAADELRVVNAAGEPVPPGEEGELLVRGPYTFNGYFRAERDNERCFDAQG 420 Query 431 FYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQY 490 F+RSGDLVR DDG +VVTGRVKDVICR GETI+A+DLEEQ+ SHPAIFSAAAV LPD Y Sbjct 421 FFRSGDLVRITDDGYVVVTGRVKDVICRGGETISAADLEEQMHSHPAIFSAAAVALPDPY 480 Query 491 LGEKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVR 550 LGEKICAAVVF G ++LAELNGYLD RGVAAH RPD LV M LPTTPIGKIDK+AI Sbjct 481 LGEKICAAVVFNGPELSLAELNGYLDGRGVAAHARPDVLVPMTTLPTTPIGKIDKKAIAG 540 Query 551 QL 552 Q+ Sbjct 541 QI 542 >gi|296170577|ref|ZP_06852161.1| mycobactin-specific salicyl-AMP ligase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894809|gb|EFG74534.1| mycobactin-specific salicyl-AMP ligase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=554 Score = 830 bits (2145), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/547 (80%), Positives = 475/547 (87%), Gaps = 4/547 (0%) Query 6 ADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDR 65 A+ R+P G L GFVPFPADRAA+YRAAGYW+GR LDT+L DAARRWP+R AV DA D Sbjct 3 ANTRQPRA-GALDGFVPFPADRAAAYRAAGYWAGRPLDTILGDAARRWPERTAVLDAAD- 60 Query 66 PGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMC 125 GLSYAELD+ ADRAAA LH LGI PGDRVLLQLPNG +FAVALF LLRAGA+PVMC Sbjct 61 --GAGLSYAELDEHADRAAAGLHRLGIAPGDRVLLQLPNGRRFAVALFGLLRAGAVPVMC 118 Query 126 LPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVS 185 LPGHRAAELGHFAAVS A+ LV+AD ASGFDYR MA EL+ + L HV+VDGDPGPF S Sbjct 119 LPGHRAAELGHFAAVSQASALVIADAASGFDYRAMADELLRANAGLEHVVVDGDPGPFTS 178 Query 186 WAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSA 245 W +LC Q G P DPGSPALLLVSGGTTG PKLIPRTHDDYVFNATASA +C L+A Sbjct 179 WTRLCDQPGGRPRVPAPDPGSPALLLVSGGTTGTPKLIPRTHDDYVFNATASAQVCGLTA 238 Query 246 DDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPAL 305 DDVYLV+L+AGHNFPLACPGLLGAMTVGAT VF DPSPEAAFAAIERHGVT TALVPAL Sbjct 239 DDVYLVLLSAGHNFPLACPGLLGAMTVGATTVFGTDPSPEAAFAAIERHGVTATALVPAL 298 Query 306 AKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRI 365 AKLWAQ+CEWEPVTPKSLRLLQVGG+KLEP+DAR +R+ALTPGLQQVFGMAEGLLN+TR Sbjct 299 AKLWAQACEWEPVTPKSLRLLQVGGAKLEPDDARLIRSALTPGLQQVFGMAEGLLNYTRP 358 Query 366 GDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERC 425 GDPPE+V+HTQGRPLCPADELR+V+A+G PV PGEEGELLVRGPYTLNGY+ AERDNERC Sbjct 359 GDPPELVDHTQGRPLCPADELRVVDAEGAPVAPGEEGELLVRGPYTLNGYYRAERDNERC 418 Query 426 FDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVG 485 FDPDGF+RSGDLVR R DG L VTGRVKDVICRAGET++A+DLEEQLL HP+IFSAAAV Sbjct 419 FDPDGFFRSGDLVRLRPDGYLTVTGRVKDVICRAGETVSAADLEEQLLHHPSIFSAAAVA 478 Query 486 LPDQYLGEKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDK 545 LPD YLGEKICAAVVF G +TLAELN +LDRRGVAAH RPD LV M ALPTTPIGK+DK Sbjct 479 LPDPYLGEKICAAVVFTGPAVTLAELNAHLDRRGVAAHARPDVLVPMAALPTTPIGKVDK 538 Query 546 RAIVRQL 552 +AI QL Sbjct 539 KAIAGQL 545 >gi|336458161|gb|EGO37144.1| peptide arylation enzyme [Mycobacterium avium subsp. paratuberculosis S397] Length=551 Score = 828 bits (2140), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/540 (79%), Positives = 464/540 (86%), Gaps = 3/540 (0%) Query 13 PDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLS 72 P G L GFVPFPA+RAA+YRAAG W+GR LDT+L+DAARRWPDR AV DA G G S Sbjct 8 PAGVLDGFVPFPAERAAAYRAAGLWTGRALDTILTDAARRWPDRTAVLDAS---GGTGFS 64 Query 73 YAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAA 132 YA LD++A+RAAA L GI PGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAA Sbjct 65 YAGLDEQANRAAAGLADAGIAPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAA 124 Query 133 ELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQ 192 ELGHFAA+S AT L++AD A+GFDYR MA L+ +H L HVIVDGDPGPF+SWAQLC + Sbjct 125 ELGHFAALSQATALLIADTAAGFDYRTMAAGLIEEHEALAHVIVDGDPGPFLSWAQLCER 184 Query 193 AGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVV 252 A G PA P DPGSPALLLVSGGTTG PKLIPRTH+DYVFNATASA LC L+ DDVYL V Sbjct 185 APAGRPATPVDPGSPALLLVSGGTTGTPKLIPRTHNDYVFNATASAELCGLTRDDVYLAV 244 Query 253 LAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQS 312 L+AGHNFPLACPGLLGAMTVGAT VF DPSPEAAFA I RHGVTVTALVPALAKLWAQ+ Sbjct 245 LSAGHNFPLACPGLLGAMTVGATTVFGTDPSPEAAFATIARHGVTVTALVPALAKLWAQA 304 Query 313 CEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVV 372 CEWE PKSLRLLQVGG+KLE +DAR +R+ALTPGLQQVFGMAEGLLN+TR+ DPPE+ Sbjct 305 CEWEDNPPKSLRLLQVGGAKLEADDARVIRSALTPGLQQVFGMAEGLLNYTRLDDPPEIT 364 Query 373 EHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFY 432 EHTQGRPL ADE+R+V+A G PV PG+EGELLVRGPYT NGYF AERDN+RCFD GF+ Sbjct 365 EHTQGRPLSTADEVRVVDAAGNPVAPGQEGELLVRGPYTFNGYFRAERDNQRCFDAQGFF 424 Query 433 RSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLG 492 RSGDLVR RDDG LVVTGRVKDVICR GETI+A+DLEEQ+LSHPAIFSAAAV LPD YLG Sbjct 425 RSGDLVRVRDDGYLVVTGRVKDVICRGGETISAADLEEQMLSHPAIFSAAAVPLPDPYLG 484 Query 493 EKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 EKICAAVVF G ++LAELNGYLD RGVAAH RPD L AMP+LPTTPIGKIDK+AI Q+ Sbjct 485 EKICAAVVFEGPALSLAELNGYLDERGVAAHARPDVLAAMPSLPTTPIGKIDKKAIANQV 544 >gi|118462251|ref|YP_881227.1| 2,3-dihydroxybenzoate-AMP ligase [Mycobacterium avium 104] gi|118163538|gb|ABK64435.1| 2,3-dihydroxybenzoate-AMP ligase [Mycobacterium avium 104] Length=551 Score = 827 bits (2135), Expect = 0.0, Method: Compositional matrix adjust. Identities = 423/540 (79%), Positives = 462/540 (86%), Gaps = 3/540 (0%) Query 13 PDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLS 72 P G L GFVPFPA+RAA+YRAAG W+GR LDT+L+DAARRWPDR AV DA G G S Sbjct 8 PAGVLDGFVPFPAERAAAYRAAGLWTGRALDTILTDAARRWPDRTAVLDAS---GGTGFS 64 Query 73 YAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAA 132 YA LD++A+RAAA L GI PGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAA Sbjct 65 YAGLDEQANRAAAGLADAGIAPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAA 124 Query 133 ELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQ 192 ELGHFAA+S AT L++AD A+GFDYR MA LV +H L HVIVDGDPGPF+SWAQLC + Sbjct 125 ELGHFAALSQATALLIADTAAGFDYRTMAAGLVEEHEALAHVIVDGDPGPFLSWAQLCER 184 Query 193 AGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVV 252 A G PA P DPGSPALLLVSGGTTG PKLIPRTHDDYVFNA ASA LC L+ DDVYL V Sbjct 185 APAGRPATPVDPGSPALLLVSGGTTGTPKLIPRTHDDYVFNANASAELCGLTRDDVYLAV 244 Query 253 LAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQS 312 L+AGHNFPLACPGLLGAMTVGAT VF DPSPEAAFA I RHGVTVTALVPALAKLWA + Sbjct 245 LSAGHNFPLACPGLLGAMTVGATTVFGTDPSPEAAFATIARHGVTVTALVPALAKLWAHA 304 Query 313 CEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVV 372 CEWE PKSLRLLQVGG+KLE +DAR +R+ALTPGLQQVFGMAEGLLN+TR+ DPPE+ Sbjct 305 CEWEDNPPKSLRLLQVGGAKLEADDARVIRSALTPGLQQVFGMAEGLLNYTRLDDPPEIT 364 Query 373 EHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFY 432 EHTQGRPL ADE+R+V+A G PV PG+EGELLVRGPYT NGYF AERDN+RCFD GF+ Sbjct 365 EHTQGRPLSTADEVRVVDAAGNPVAPGQEGELLVRGPYTFNGYFRAERDNQRCFDAQGFF 424 Query 433 RSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLG 492 RSGDLVR RDDG LVVTGRVKDVICR GETI+A+DLEEQ+LSHPAIFSAAAV LPD YLG Sbjct 425 RSGDLVRVRDDGYLVVTGRVKDVICRGGETISAADLEEQMLSHPAIFSAAAVPLPDPYLG 484 Query 493 EKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 EKICAAVVF G ++LAELNGYLD RGVAAH RPD L AMP+LPTTPIGKIDK+AI Q+ Sbjct 485 EKICAAVVFEGPALSLAELNGYLDERGVAAHARPDVLAAMPSLPTTPIGKIDKKAIANQV 544 >gi|254821622|ref|ZP_05226623.1| 2,3-dihydroxybenzoate-AMP ligase [Mycobacterium intracellulare ATCC 13950] Length=530 Score = 827 bits (2135), Expect = 0.0, Method: Compositional matrix adjust. Identities = 431/534 (81%), Positives = 466/534 (88%), Gaps = 9/534 (1%) Query 21 VPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQRA 80 +PFPADRAA+YRAAGYW+GRTLDT+L+DAAR+WPDR AV DA G G SYA+LD +A Sbjct 1 MPFPADRAAAYRAAGYWAGRTLDTILTDAARQWPDRTAVRDA---VGGTGFSYADLDDQA 57 Query 81 DRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAAV 140 +RAA L LGI PGDRVLLQLPN CQFAVALF LLRAGA+PVMCLPGHRAAELGHFAAV Sbjct 58 NRAAGGLRALGIAPGDRVLLQLPNSCQFAVALFGLLRAGAVPVMCLPGHRAAELGHFAAV 117 Query 141 SAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSPAP 200 SAATGL++AD A+GFDYR MA L+ +HPTLRHVIVDGDPGPF SWAQLC QA P P Sbjct 118 SAATGLLIADTAAGFDYRTMALGLIEEHPTLRHVIVDGDPGPFTSWAQLCEQA----PGP 173 Query 201 P--ADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHN 258 P ADPGSPALLLVSGGTTG PKLIPRTHDDYVFNATASA LCRL+ DDVYL VL+AGHN Sbjct 174 PSSADPGSPALLLVSGGTTGTPKLIPRTHDDYVFNATASAELCRLTCDDVYLAVLSAGHN 233 Query 259 FPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPV 318 FPLACPGLLGAMTVGAT VF DPSPEAAFAAI+RHGVTVTALVPALAKLWAQ+CEWEPV Sbjct 234 FPLACPGLLGAMTVGATTVFGTDPSPEAAFAAIDRHGVTVTALVPALAKLWAQACEWEPV 293 Query 319 TPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGR 378 TPK+LRLLQVGG+KLEPEDAR VRTALTPGLQQVFGMAEGLLN+TR DPPE+ EHTQGR Sbjct 294 TPKTLRLLQVGGAKLEPEDARLVRTALTPGLQQVFGMAEGLLNYTRPDDPPELTEHTQGR 353 Query 379 PLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLV 438 PL ADELR+VNA GEP+ PGEEGELLVRGPYT NGYF AERDNERCFD GF+RSGDLV Sbjct 354 PLSAADELRVVNAAGEPMPPGEEGELLVRGPYTFNGYFRAERDNERCFDAQGFFRSGDLV 413 Query 439 RRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKICAA 498 R DDG +VVTGRVKDVICR GETI+A+DLEEQ+ SHPAIFSAAAV LPD YLGEKICAA Sbjct 414 RITDDGYVVVTGRVKDVICRGGETISAADLEEQMHSHPAIFSAAAVALPDPYLGEKICAA 473 Query 499 VVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 +VF G ++LAELNGYLD RGVAAH RPD LV M LPTTPIGKIDK+AI Q+ Sbjct 474 IVFNGPELSLAELNGYLDGRGVAAHARPDVLVPMTTLPTTPIGKIDKKAIAGQI 527 >gi|342857514|ref|ZP_08714170.1| 2,3-dihydroxybenzoate-AMP ligase [Mycobacterium colombiense CECT 3035] gi|342134847|gb|EGT88013.1| 2,3-dihydroxybenzoate-AMP ligase [Mycobacterium colombiense CECT 3035] Length=548 Score = 810 bits (2091), Expect = 0.0, Method: Compositional matrix adjust. Identities = 419/536 (79%), Positives = 465/536 (87%), Gaps = 3/536 (0%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L GFVPFPADRAA+YRAAGYW+GR LD +L+DAA++WPDR AV DA G GLSYA+L Sbjct 13 LDGFVPFPADRAAAYRAAGYWAGRPLDAILTDAAQQWPDRTAVVDA---MGDTGLSYADL 69 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D +A+RAA+ L G GI PGDRVL+QLPNGCQFAVALF LLRAGAIPVMCLPGHRAAE+GH Sbjct 70 DDQANRAASGLRGAGIAPGDRVLVQLPNGCQFAVALFGLLRAGAIPVMCLPGHRAAEMGH 129 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 FAAVS AT L++AD A GFDYR MAR LV L HVIVDGDPGPF SWAQL +A TG Sbjct 130 FAAVSGATALLIADTAGGFDYRTMARGLVERCTALEHVIVDGDPGPFTSWAQLRDRAVTG 189 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 +P DPGSPALLLVSGGTTGMPKLIPRTHDDYVFNA ASA LC L+ +DVYL VL+AG Sbjct 190 APLSAPDPGSPALLLVSGGTTGMPKLIPRTHDDYVFNARASAELCGLTGEDVYLAVLSAG 249 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HNFPLACPGLLGAMT GAT VF DPSPEAAFAA+ RHGVTVTALVPALAKLWAQ+C+WE Sbjct 250 HNFPLACPGLLGAMTAGATTVFGTDPSPEAAFAAVARHGVTVTALVPALAKLWAQACDWE 309 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 PVTPK+LRLLQ+GG++LEPEDAR VR ALTPGLQQVFGMAEGLLN+TR+ DP E+ EHTQ Sbjct 310 PVTPKTLRLLQIGGARLEPEDARLVRAALTPGLQQVFGMAEGLLNYTRLDDPAELTEHTQ 369 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRPLCPADELR+V+A+G+PV GEEGELLVRGPYT NGYF A+RDNER FDPDGF+RSGD Sbjct 370 GRPLCPADELRVVDAEGKPVPQGEEGELLVRGPYTFNGYFRADRDNERSFDPDGFFRSGD 429 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 +VR R+DG LVVTGRVKDVICR GETI+A+DLEEQL HPAIFSAAAV LPD+YLGEKIC Sbjct 430 VVRLRNDGYLVVTGRVKDVICRGGETISAADLEEQLHGHPAIFSAAAVALPDRYLGEKIC 489 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 AAVVF G +TLAE+NGYLD+RGVAAH RPD LVAM +LPTTPIGKIDK+AI Q+ Sbjct 490 AAVVFNGPELTLAEVNGYLDQRGVAAHARPDVLVAMTSLPTTPIGKIDKKAIAGQV 545 >gi|183983678|ref|YP_001851969.1| bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase [Mycobacterium marinum M] gi|183177004|gb|ACC42114.1| bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase [Mycobacterium marinum M] Length=550 Score = 788 bits (2035), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/559 (72%), Positives = 450/559 (81%), Gaps = 14/559 (2%) Query 1 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA 60 MP +A RP P + GF+P+P +R ASYRAAGYW+GR++ ++L AA RWPDR+ V Sbjct 1 MPVTSAQPPRPGP---VAGFIPYPPERVASYRAAGYWTGRSIGSLLRQAAARWPDRVGVV 57 Query 61 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA 120 DAG ++ ELD+ ADRAAA LGI PGDRVLLQLPN C+FAVALF LLRAGA Sbjct 58 DAG-----ASHTFCELDKLADRAAAGFVSLGIAPGDRVLLQLPNSCRFAVALFGLLRAGA 112 Query 121 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP 180 IPVMCLPGHR AEL HFA VS A GL+VA A GFDYR MA LVA HP LRHVI+DG+ Sbjct 113 IPVMCLPGHRLAELHHFAEVSGAVGLIVAQHAGGFDYRSMAERLVAAHPQLRHVIIDGES 172 Query 181 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL 240 GPF+ W+ L A +P D SPALLLVSGGTTG PKLIPRTHDDYV+NATASA L Sbjct 173 GPFLPWSSLSEGA---TPDIDVDTTSPALLLVSGGTTGTPKLIPRTHDDYVYNATASAQL 229 Query 241 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA 300 CRL+ADDVYLV L A HNFPLACPG+LG+M VGAT VF+ DPSPEAAF IERHGVTVTA Sbjct 230 CRLTADDVYLVSLPAAHNFPLACPGILGSMAVGATIVFSTDPSPEAAFTLIERHGVTVTA 289 Query 301 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLL 360 LVPALAKLW Q+C+WEPVTPKSLRLLQVGGS+LEPEDAR+ R ALTPGLQQVFGMAEGLL Sbjct 290 LVPALAKLWTQACDWEPVTPKSLRLLQVGGSRLEPEDARQAREALTPGLQQVFGMAEGLL 349 Query 361 NFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAER 420 NFTR+ DPP+++EHTQGRPLC ADELRIV+ G PV PG EGELLVRGPYT+NGYF A+R Sbjct 350 NFTRLEDPPDLLEHTQGRPLCSADELRIVDGAGAPVAPGAEGELLVRGPYTINGYFCADR 409 Query 421 DNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFS 480 DNERCFDP GFYRSGDLVR RDDG L VTGRVKDVICR GETI+A DLEEQLLSHPAI S Sbjct 410 DNERCFDPAGFYRSGDLVRLRDDGYLQVTGRVKDVICRCGETISAQDLEEQLLSHPAIRS 469 Query 481 AAAVGLPDQYLGEKICAAVVFAG---APITLAELNGYLDRRGVAAHTRPDQLVAMPALPT 537 AAAV LPD +GE ICAA+VFAG P TL+ LN YL++RGVAAH R D+LVAMP+LPT Sbjct 470 AAAVPLPDPDMGELICAAIVFAGPPQTPQTLSGLNDYLEQRGVAAHIRIDRLVAMPSLPT 529 Query 538 TPIGKIDKRAIVRQLGIAT 556 TP+GKIDK+AI Q+ T Sbjct 530 TPVGKIDKKAIASQILTTT 548 >gi|118618913|ref|YP_907245.1| bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase [Mycobacterium ulcerans Agy99] gi|118571023|gb|ABL05774.1| bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase [Mycobacterium ulcerans Agy99] Length=537 Score = 782 bits (2020), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/543 (73%), Positives = 441/543 (82%), Gaps = 11/543 (2%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 + GF+P+P +R ASYRAAGYW+GR++ ++L AA RWPDR+ V DAG ++ EL Sbjct 1 MAGFIPYPPERVASYRAAGYWTGRSIGSLLRQAAARWPDRVGVVDAG-----ASHTFCEL 55 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D+ ADR AA LGI PGDRVLLQLPN C+FAVALF LLRAGAIPVMCLPGHR AEL H Sbjct 56 DKLADRVAAGFVSLGIAPGDRVLLQLPNSCRFAVALFGLLRAGAIPVMCLPGHRLAELHH 115 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 FA VS A GL+VA A GFDYR MA LVA HP LRHVI+DG+ GPF+ W+ L A Sbjct 116 FAEVSGAVGLIVAQHAGGFDYRSMAERLVAAHPQLRHVIIDGESGPFLPWSSLSEGA--- 172 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 +P D SPALLLVSGGTTG PKLIPRTHDDYV+NATASA LCRL+ADDVYLV L A Sbjct 173 TPDIDVDTTSPALLLVSGGTTGTPKLIPRTHDDYVYNATASAQLCRLTADDVYLVSLPAA 232 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HNFPLACPG+LG+M VGAT VF+ DPSPEAAF IERHGVTVTALVPALAKLW Q+C+WE Sbjct 233 HNFPLACPGILGSMAVGATIVFSTDPSPEAAFTLIERHGVTVTALVPALAKLWTQACDWE 292 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 PV PKSLRLLQVGGS+LEPEDAR+ R ALTPGLQQVFGMAEGLLNFTR+ DPP+++EHTQ Sbjct 293 PVIPKSLRLLQVGGSRLEPEDARQAREALTPGLQQVFGMAEGLLNFTRLEDPPDLLEHTQ 352 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRPLC ADELRIV+ G PV PG EGELLVRGPYT+NGYF A+RDNERCFDP GFYRSGD Sbjct 353 GRPLCSADELRIVDGAGAPVAPGAEGELLVRGPYTINGYFCADRDNERCFDPAGFYRSGD 412 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LVR RDDG L VTGRVKDVICR GETI+A DLEEQLLSHPAI SAAAV LPD +GE IC Sbjct 413 LVRLRDDGYLQVTGRVKDVICRCGETISAQDLEEQLLSHPAIRSAAAVPLPDPDMGELIC 472 Query 497 AAVVFAG---APITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLG 553 AA+VFAG P TL+ LN YL++RGVAAH R D+LVAMP+LPTTP+GKIDK+AI Q+ Sbjct 473 AAIVFAGPPQTPQTLSGLNDYLEQRGVAAHIRIDRLVAMPSLPTTPVGKIDKKAIASQIL 532 Query 554 IAT 556 T Sbjct 533 TTT 535 >gi|240169929|ref|ZP_04748588.1| bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase [Mycobacterium kansasii ATCC 12478] Length=551 Score = 759 bits (1961), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/543 (73%), Positives = 435/543 (81%), Gaps = 11/543 (2%) Query 9 RRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGH 68 RRP+ L GFVPFP DR +YR AGYW+GRT+D++L AA WP R+AVADA R Sbjct 9 RRPA---SLHGFVPFPPDRETAYRTAGYWTGRTVDSLLRRAATAWPGRVAVADAVGRH-- 63 Query 69 GGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPG 128 +Y+ELD+ ADRAAA LG+ P DRV+LQLPN +F VALF LLRAGAIPVMCLPG Sbjct 64 ---TYSELDELADRAAAGFAALGVAPRDRVVLQLPNSARFCVALFGLLRAGAIPVMCLPG 120 Query 129 HRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQ 188 HR AEL HF VS A GLVVA+ A GF YRPMA +L A HP LRHVI+DG+ GPF+SW+ Sbjct 121 HRFAELDHFVGVSGAIGLVVAETAGGFHYRPMAEQLAAAHPQLRHVIIDGNAGPFLSWSA 180 Query 189 LCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDV 248 L G P AD +PALLLVSGGTTG PKLIPRTHDDYV+NATASA LC L+ DDV Sbjct 181 L---PGGRPPDIAADTAAPALLLVSGGTTGTPKLIPRTHDDYVYNATASAELCGLTCDDV 237 Query 249 YLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKL 308 YLV L A HNF LACPG+LG ++ G T VF DPSPEAAFA IERHGVTVTALVPALAKL Sbjct 238 YLVALPAAHNFALACPGILGTLSAGGTVVFGTDPSPEAAFATIERHGVTVTALVPALAKL 297 Query 309 WAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDP 368 WAQ+C WEPVTPK+LRLLQVGGSKLEPEDAR VR ALTPGLQQVFGMAEGLLNFTR+ DP Sbjct 298 WAQACHWEPVTPKTLRLLQVGGSKLEPEDARAVRAALTPGLQQVFGMAEGLLNFTRLEDP 357 Query 369 PEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDP 428 PEVVEHTQGRPLC ADELR+V+ADG PV PG EGELL RGPYT+NGYF AE DN+ CFDP Sbjct 358 PEVVEHTQGRPLCAADELRVVDADGHPVAPGAEGELLTRGPYTINGYFRAEHDNQLCFDP 417 Query 429 DGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPD 488 DGFYRSGDLVR R+DG LVVTGRVKDVICRAGET++A +LEEQLL HP I SAAAV LPD Sbjct 418 DGFYRSGDLVRLREDGYLVVTGRVKDVICRAGETVSAQELEEQLLRHPGIGSAAAVPLPD 477 Query 489 QYLGEKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAI 548 LGE CAAVVF GAPITLAELNGYLD RGVA H R D L+ + +LPTT +GKIDK+AI Sbjct 478 PALGEIACAAVVFVGAPITLAELNGYLDERGVAVHARLDMLLPLASLPTTAVGKIDKKAI 537 Query 549 VRQ 551 RQ Sbjct 538 ARQ 540 >gi|118468444|ref|YP_888788.1| 2,3-dihydroxybenzoate-AMP ligase [Mycobacterium smegmatis str. MC2 155] gi|118169731|gb|ABK70627.1| 2,3-dihydroxybenzoate-AMP ligase [Mycobacterium smegmatis str. MC2 155] Length=558 Score = 754 bits (1948), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/541 (71%), Positives = 435/541 (81%), Gaps = 9/541 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L GF PFPA+RA +YRAAGYW + LD+VL AAR WPD +AV DA R +YAEL Sbjct 22 LAGFTPFPAERAQAYRAAGYWRDQLLDSVLRTAARTWPDHIAVIDADHRH-----TYAEL 76 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D+ ADRAAA + GLGI PGDRVL+QLPN +FAVALF LLRAGA+PVMCLPGHR AEL H Sbjct 77 DRLADRAAAGIAGLGIRPGDRVLVQLPNTAEFAVALFGLLRAGAVPVMCLPGHRLAELTH 136 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 FA VS+A LVVAD A GFD+R +ARELV HP +RHV+VDGD F+SWA++ A Sbjct 137 FAEVSSAVALVVADTAGGFDHRDLARELVRSHPDVRHVLVDGDAAEFLSWAEVTRAAPGP 196 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P DP +PALLLVSGGTTG PKLIPRTH DYV+NATASA LCRL+ADDVYLV L A Sbjct 197 VPEIAPDPAAPALLLVSGGTTGAPKLIPRTHQDYVYNATASAELCRLTADDVYLVALPAA 256 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HNFPLACPGLLGAMTVGAT VF DPSPEAAFAAI+ HGVT TALVPALAKLWAQ+C WE Sbjct 257 HNFPLACPGLLGAMTVGATTVFTTDPSPEAAFAAIDEHGVTATALVPALAKLWAQACAWE 316 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 P+ PK+LRLLQVGG+KL DA VR ALTPGLQQVFGMAEGLLN+TRIGDPPEV+E+TQ Sbjct 317 PLAPKTLRLLQVGGAKLAAPDAALVRGALTPGLQQVFGMAEGLLNYTRIGDPPEVLENTQ 376 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRPL P DE+RIV+ G V PG EGELLVRGPYTLNGYF AE NER F PDGFYRSGD Sbjct 377 GRPLSPDDEIRIVDEVGNEVPPGAEGELLVRGPYTLNGYFNAEAANERSFSPDGFYRSGD 436 Query 437 LVRRRDDGNLV----VTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLG 492 VRR DG L VTGR+KDVI R GE ++A DLEE LL+HP++++AAAV LPD++LG Sbjct 437 RVRRFADGPLAGYLEVTGRIKDVIVRGGENVSALDLEEHLLTHPSVWAAAAVALPDEFLG 496 Query 493 EKICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 EKICA VVF G P++LAEL+ +L++RGVAAH+RPD LV MP+LPTT +GKIDK+AIVRQL Sbjct 497 EKICAVVVFNGPPVSLAELHAHLEQRGVAAHSRPDALVPMPSLPTTAVGKIDKKAIVRQL 556 Query 553 G 553 G Sbjct 557 G 557 >gi|289758509|ref|ZP_06517887.1| salicyl-AMP ligase + salicyl-S-arcp synthetase [Mycobacterium tuberculosis T85] gi|289714073|gb|EFD78085.1| salicyl-AMP ligase + salicyl-S-arcp synthetase [Mycobacterium tuberculosis T85] Length=359 Score = 707 bits (1824), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/358 (100%), Positives = 358/358 (100%), Gaps = 0/358 (0%) Query 1 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA 60 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA Sbjct 1 MPPKAADGRRPSPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVA 60 Query 61 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA 120 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA Sbjct 61 DAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGA 120 Query 121 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP 180 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP Sbjct 121 IPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDP 180 Query 181 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL 240 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL Sbjct 181 GPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAAL 240 Query 241 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA 300 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA Sbjct 241 CRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTA 300 Query 301 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEG 358 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEG Sbjct 301 LVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEG 358 >gi|126436060|ref|YP_001071751.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS] gi|126235860|gb|ABN99260.1| AMP-dependent synthetase and ligase [Mycobacterium sp. JLS] Length=549 Score = 705 bits (1819), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/538 (67%), Positives = 412/538 (77%), Gaps = 9/538 (1%) Query 19 GFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQ 78 GFVPFP DRA YR AGYW+GR L+++L DAA R PD AV D G L++AEL Sbjct 15 GFVPFPEDRAEQYRRAGYWTGRPLESLLLDAAHRRPDHPAVVDV-----DGSLTFAELTA 69 Query 79 RADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFA 138 RAD AAAL GLGI PGDRVLLQLPN +FAVA F LLRAGA+PVMCLPGHR AELGHFA Sbjct 70 RADTVAAALAGLGIRPGDRVLLQLPNSVRFAVAFFGLLRAGAVPVMCLPGHRTAELGHFA 129 Query 139 AVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSP 198 VS A L+V D GFDYR MA +LVAD PTLRHV+VDGDPGPF+SWA L G Sbjct 130 DVSGAVALIVPDEVGGFDYREMAAQLVADRPTLRHVLVDGDPGPFLSWAALIDSGGVAPE 189 Query 199 APPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHN 258 P D PALLLVSGGTTG+PKLIPRTHDDYV+ A +SA C + DDVYLV L AGHN Sbjct 190 IGPVDTSLPALLLVSGGTTGLPKLIPRTHDDYVYTAVSSAQACHFTPDDVYLVALPAGHN 249 Query 259 FPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPV 318 FPLACPG+LGAMTVGAT VF DPSPE AFA I++H VTVT LV AL KLWAQ+C+WEPV Sbjct 250 FPLACPGMLGAMTVGATTVFTADPSPEEAFALIDKHQVTVTGLVNALGKLWAQACDWEPV 309 Query 319 TPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGR 378 P SLRL+QVGGS++ PE+AR + LTPGL Q+FGMAEG+LNFTR GDP +VV HTQGR Sbjct 310 LPTSLRLVQVGGSRMSPEEARFILDLLTPGLSQIFGMAEGMLNFTRPGDPLDVVVHTQGR 369 Query 379 PLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLV 438 P+ P DE+R+V+ G V PGEEGELLVRGP TLNGY+ A+ N RCF PDGFYR+GD V Sbjct 370 PVSPHDEMRVVDESGVEVAPGEEGELLVRGPNTLNGYYRADEANARCFSPDGFYRTGDRV 429 Query 439 RRRDD----GNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEK 494 R D GN+ VTGR+KDVI R GET++A+DLE+ LL+HPAI++AAAV LPD YLGEK Sbjct 430 RIFADGPLAGNVEVTGRIKDVIHRGGETVSATDLEDHLLTHPAIYAAAAVALPDDYLGEK 489 Query 495 ICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 ICAAVVF G +TLAELN +LD RG + H RPD L AMP+LP T +GK+DK+ +V QL Sbjct 490 ICAAVVFRGKQLTLAELNAFLDERGASTHARPDVLAAMPSLPLTAVGKVDKKKLVEQL 547 >gi|108800437|ref|YP_640634.1| AMP-dependent synthetase and ligase [Mycobacterium sp. MCS] gi|119869566|ref|YP_939518.1| AMP-dependent synthetase and ligase [Mycobacterium sp. KMS] gi|108770856|gb|ABG09578.1| AMP-dependent synthetase and ligase [Mycobacterium sp. MCS] gi|119695655|gb|ABL92728.1| AMP-dependent synthetase and ligase [Mycobacterium sp. KMS] Length=549 Score = 704 bits (1817), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/538 (67%), Positives = 412/538 (77%), Gaps = 9/538 (1%) Query 19 GFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQ 78 GFVPFP DRA YR AGYW+GR L+++L DAA R PD AV D G L++AEL Sbjct 15 GFVPFPEDRAEQYRRAGYWTGRPLESLLLDAAHRRPDHPAVVDV-----DGSLTFAELTA 69 Query 79 RADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFA 138 RAD AAAL GLGI PGDRVLLQLPN +FAVA F LLRAGA+PVMCLPGHR AELGHFA Sbjct 70 RADTVAAALAGLGIRPGDRVLLQLPNSVRFAVAFFGLLRAGAVPVMCLPGHRTAELGHFA 129 Query 139 AVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSP 198 VS A L+V D GFDYR MA +LVAD PTLRHV+VDGDPGPF+SWA L G Sbjct 130 DVSGAVALIVPDEVGGFDYREMAAQLVADRPTLRHVLVDGDPGPFLSWAALIDSGGVAPE 189 Query 199 APPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHN 258 P D PALLLVSGGTTG+PKLIPRTHDDYV+ A +SA C + DDVYLV L AGHN Sbjct 190 IGPVDTSLPALLLVSGGTTGLPKLIPRTHDDYVYTAVSSAQACHFTPDDVYLVALPAGHN 249 Query 259 FPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPV 318 FPLACPG+LGAMTVGAT VF DPSPE AFA I++H VTVT LV AL KLWAQ+C+WEPV Sbjct 250 FPLACPGMLGAMTVGATTVFTADPSPEEAFALIDKHQVTVTGLVNALGKLWAQACDWEPV 309 Query 319 TPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGR 378 P SLRL+QVGGS++ PE+AR + LTPGL Q+FGMAEG+LNFTR GDP +VV HTQGR Sbjct 310 LPTSLRLVQVGGSRMSPEEARFILDRLTPGLSQIFGMAEGMLNFTRPGDPLDVVVHTQGR 369 Query 379 PLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLV 438 P+ P DE+R+V+ G V PGEEGELLVRGP TLNGY+ A+ N RCF PDGFYR+GD V Sbjct 370 PVSPHDEMRVVDESGVEVAPGEEGELLVRGPNTLNGYYRADEANARCFSPDGFYRTGDRV 429 Query 439 RRRDD----GNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEK 494 R D GN+ VTGR+KDVI R GET++A+DLE+ LL+HPAI++AAAV LPD YLGEK Sbjct 430 RIFADGPLAGNVEVTGRIKDVIHRGGETVSATDLEDHLLTHPAIYAAAAVALPDDYLGEK 489 Query 495 ICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 ICAAVVF G +TLAELN +LD RG + H RPD L AMP+LP T +GK+DK+ +V QL Sbjct 490 ICAAVVFRGKQLTLAELNAFLDERGASTHARPDVLAAMPSLPLTAVGKVDKKKLVAQL 547 >gi|315443738|ref|YP_004076617.1| peptide arylation enzyme [Mycobacterium sp. Spyr1] gi|315262041|gb|ADT98782.1| peptide arylation enzyme [Mycobacterium sp. Spyr1] Length=562 Score = 681 bits (1756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/538 (66%), Positives = 413/538 (77%), Gaps = 9/538 (1%) Query 19 GFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQ 78 GFVPFP DRA +YR AGYW+GR LD++L+DAA RWPD+ A+ DA ++AELD Sbjct 26 GFVPFPEDRAEAYRRAGYWTGRPLDSILTDAASRWPDKPAIIDATR-----SYTFAELDA 80 Query 79 RADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFA 138 ADRAAA L LGI PG+RVLLQLPN CQFAVALFALLRAG +PVMCL GHR AELGHFA Sbjct 81 AADRAAAGLADLGIRPGERVLLQLPNSCQFAVALFALLRAGVVPVMCLTGHRTAELGHFA 140 Query 139 AVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSP 198 VS A ++V D A GFDYR MA L A P LRHVIVDG+PG VSW + AG Sbjct 141 DVSGAVAVIVPDRAGGFDYRDMAASLAAQRPALRHVIVDGEPGDQVSWQSILDFAGPRLG 200 Query 199 APPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHN 258 P DP PALLLVSGGTTG+PKLI RTHDDYV+NA A A C ++ +D YLV L AGHN Sbjct 201 RTPVDPSLPALLLVSGGTTGLPKLIARTHDDYVYNAHACAQACEMTGEDAYLVALPAGHN 260 Query 259 FPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPV 318 FPLACPGLLG+MTVGA VF DPSPE AFA I++H +TVT LV ALAKLWAQ+C+WEPV Sbjct 261 FPLACPGLLGSMTVGAPTVFTADPSPENAFALIDKHRITVTGLVNALAKLWAQACDWEPV 320 Query 319 TPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGR 378 P SLR +QVGGS++ PE+AR + LTPG+ Q+FGMAEG+LNFTR GDP +VV HTQGR Sbjct 321 LPTSLRFVQVGGSRMSPEEARFILDRLTPGMSQIFGMAEGMLNFTRPGDPEDVVVHTQGR 380 Query 379 PLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLV 438 P+ P DE+R+V+ DG V PGEEGELLVRGPYTLNGY+ A+ N R F PDGFYR+GD V Sbjct 381 PMSPHDEMRVVDEDGVEVAPGEEGELLVRGPYTLNGYYRADDANARSFTPDGFYRTGDRV 440 Query 439 RRRDD----GNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEK 494 R D G + VTGRVKDVI R GET++A+DLE+ L +HP++++AAAV LPD+YLGEK Sbjct 441 RIFTDGPRAGYVEVTGRVKDVIHRGGETVSATDLEDHLHTHPSVYAAAAVALPDEYLGEK 500 Query 495 ICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 ICAAVVF G P+TLA+LN +LD RG + H RPD LV +P+LPTT +GK+DK+A+V QL Sbjct 501 ICAAVVFTGPPLTLADLNAFLDERGASTHARPDVLVPVPSLPTTAVGKVDKKALVAQL 558 >gi|145223278|ref|YP_001133956.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] gi|145215764|gb|ABP45168.1| AMP-dependent synthetase and ligase [Mycobacterium gilvum PYR-GCK] Length=557 Score = 681 bits (1756), Expect = 0.0, Method: Compositional matrix adjust. Identities = 350/538 (66%), Positives = 413/538 (77%), Gaps = 9/538 (1%) Query 19 GFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQ 78 GFVPFP DRA +YR AGYW+GR LD++L+DAA RWPD+ A+ DA ++AELD Sbjct 21 GFVPFPEDRAEAYRRAGYWTGRPLDSILTDAASRWPDKPAIIDATR-----SYTFAELDA 75 Query 79 RADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFA 138 ADRAAA L LGI PG+RVLLQLPN CQFAVALFALLRAG +PVMCL GHR AELGHFA Sbjct 76 AADRAAAGLADLGIRPGERVLLQLPNSCQFAVALFALLRAGVVPVMCLTGHRTAELGHFA 135 Query 139 AVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSP 198 VS A ++V D A GFDYR MA L A P LRHVIVDG+PG VSW + AG Sbjct 136 DVSGAVAVIVPDRAGGFDYRDMAASLAAQRPALRHVIVDGEPGDQVSWQSILDFAGPRLG 195 Query 199 APPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHN 258 P DP PALLLVSGGTTG+PKLI RTHDDYV+NA A A C ++ +D YLV L AGHN Sbjct 196 RTPVDPSLPALLLVSGGTTGLPKLIARTHDDYVYNAHACAQACEMTGEDAYLVALPAGHN 255 Query 259 FPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPV 318 FPLACPGLLG+MTVGA VF DPSPE AFA I++H +TVT LV ALAKLWAQ+C+WEPV Sbjct 256 FPLACPGLLGSMTVGAPTVFTADPSPENAFALIDKHRITVTGLVNALAKLWAQACDWEPV 315 Query 319 TPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGR 378 P SLR +QVGGS++ PE+AR + LTPG+ Q+FGMAEG+LNFTR GDP +VV HTQGR Sbjct 316 LPTSLRFVQVGGSRMSPEEARFILDRLTPGMSQIFGMAEGMLNFTRPGDPEDVVVHTQGR 375 Query 379 PLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLV 438 P+ P DE+R+V+ DG V PGEEGELLVRGPYTLNGY+ A+ N R F PDGFYR+GD V Sbjct 376 PMSPHDEMRVVDEDGVEVAPGEEGELLVRGPYTLNGYYRADDANARSFTPDGFYRTGDRV 435 Query 439 RRRDD----GNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEK 494 R D G + VTGRVKDVI R GET++A+DLE+ L +HP++++AAAV LPD+YLGEK Sbjct 436 RIFTDGPRAGYVEVTGRVKDVIHRGGETVSATDLEDHLHTHPSVYAAAAVALPDEYLGEK 495 Query 495 ICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 ICAAVVF G P+TLA+LN +LD RG + H RPD LV +P+LPTT +GK+DK+A+V QL Sbjct 496 ICAAVVFTGPPLTLADLNAFLDERGASTHARPDVLVPVPSLPTTAVGKVDKKALVAQL 553 >gi|120404808|ref|YP_954637.1| AMP-dependent synthetase and ligase [Mycobacterium vanbaalenii PYR-1] gi|119957626|gb|ABM14631.1| AMP-dependent synthetase and ligase [Mycobacterium vanbaalenii PYR-1] Length=550 Score = 674 bits (1738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/538 (64%), Positives = 408/538 (76%), Gaps = 9/538 (1%) Query 19 GFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQ 78 GFVPFP DRA YR AGYW+GR LD++L++AA WPD+ AV D+ ++ ELD Sbjct 16 GFVPFPPDRAEVYRRAGYWTGRPLDSILTEAAATWPDKPAVIDSAQT-----YTFRELDA 70 Query 79 RADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFA 138 ADR AA L LGI PGDRVLLQLPN CQFA+ALF LLRA A+PVMCLPGHR AELGHFA Sbjct 71 AADRVAAGLAALGIRPGDRVLLQLPNSCQFAIALFGLLRAAAVPVMCLPGHRTAELGHFA 130 Query 139 AVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSP 198 VS A L+V D A GFDYR MA L A+HP+L+HVIVDG+ GPFV+W+ + G Sbjct 131 EVSGAVALIVPDEAGGFDYRDMAGRLAAEHPSLQHVIVDGENGPFVAWSSIRDFDGPAVE 190 Query 199 APPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHN 258 DPG PALLLVSGGTTG+PKLI RTHDDYV+NA ASA C ++A+D YLV L AGHN Sbjct 191 RAAVDPGLPALLLVSGGTTGLPKLIARTHDDYVYNAVASAQACEMTAEDAYLVALPAGHN 250 Query 259 FPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPV 318 FPLACPG+LG+MTVGA VF DPSPE AFA I++ +TVT LV ALAKLWAQ+CEWEPV Sbjct 251 FPLACPGMLGSMTVGAPTVFTADPSPENAFALIDKFRITVTGLVNALAKLWAQACEWEPV 310 Query 319 TPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGR 378 P SLR +QVGGS++ PE+AR + LTPG+ Q+FGMAEG+LNFTR GDP +VV HTQGR Sbjct 311 LPTSLRFVQVGGSRMSPEEARFILERLTPGMSQIFGMAEGMLNFTRPGDPEDVVVHTQGR 370 Query 379 PLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLV 438 P+ P DE+R+V+ G+ V PGEEGELLVRGPYTL GY+ + N R F PDGFYR+GD V Sbjct 371 PMSPHDEVRVVDESGDGVPPGEEGELLVRGPYTLYGYYRDDDANARSFSPDGFYRTGDRV 430 Query 439 RRRDD----GNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEK 494 R D G + V GR+KDVI R GET++A+DLE+ L +HPAI++AAAV LPD+YLGEK Sbjct 431 RIFADGPRAGYVEVVGRIKDVIHRGGETVSATDLEDHLHTHPAIYAAAAVALPDEYLGEK 490 Query 495 ICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 ICAAVVF G PITLAELN +LD RG + H RPD L+ + +LPTT +GK+DK+ + QL Sbjct 491 ICAAVVFRGKPITLAELNAFLDERGASKHARPDVLMPVRSLPTTAVGKVDKKQLGAQL 548 >gi|333990168|ref|YP_004522782.1| bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase)/salicyl-S-ACP synthetase [Mycobacterium sp. JDM601] gi|333486136|gb|AEF35528.1| bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase [Mycobacterium sp. JDM601] Length=513 Score = 663 bits (1711), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/516 (65%), Positives = 397/516 (77%), Gaps = 9/516 (1%) Query 42 LDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQ 101 +D++L++AA WP R AV DAG S+AELD ADR AA L LGI GDRVLLQ Sbjct 1 MDSILTEAASNWPQRPAVIDAGR-----SYSFAELDSAADRFAAGLARLGIAAGDRVLLQ 55 Query 102 LPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMA 161 LPN QFA+A F +LRAGA+PVMCLPGHRAAELGHFA VS A L++AD A GFDYR +A Sbjct 56 LPNSTQFALAFFGVLRAGAVPVMCLPGHRAAELGHFADVSDAVALIIADRAGGFDYRELA 115 Query 162 RELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPK 221 + L+HVIVDGDPGPF W+ + AG D +PALLLVSGGTTGMPK Sbjct 116 ARVTEGRSRLQHVIVDGDPGPFTVWSTVAQCAGPAVQRADVDTTTPALLLVSGGTTGMPK 175 Query 222 LIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPD 281 LIPRTHDDY++N TA A C L+ DDVYLV L AGHNFPL CPG+LGAMTVGA VF D Sbjct 176 LIPRTHDDYLYNTTACAQACGLTGDDVYLVALPAGHNFPLGCPGMLGAMTVGAATVFTAD 235 Query 282 PSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRV 341 PSPEAAFA I RHGVT TALV ALAKLWAQ+C+WEP P +LRLLQVGGS++ P++AR + Sbjct 236 PSPEAAFALIHRHGVTATALVNALAKLWAQACDWEPNPPTALRLLQVGGSRMAPDEARYL 295 Query 342 RTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEE 401 R L PGLQQ+FGMAEG+LNFTR GDP EVVE TQGRP+ P DELR+V+ +GE V PGEE Sbjct 296 RETLGPGLQQIFGMAEGMLNFTRPGDPVEVVEQTQGRPMSPHDELRVVDDNGEDVAPGEE 355 Query 402 GELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLVRRRDD----GNLVVTGRVKDVIC 457 GELLVRGPYTLNGY+ A++ N R F PDGF+R+GD VR D GN+ VTGR+KDVI Sbjct 356 GELLVRGPYTLNGYYRADQANARSFSPDGFFRTGDQVRIFADGPLAGNVEVTGRIKDVIH 415 Query 458 RAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKICAAVVFAGAPITLAELNGYLDR 517 R GET++ASD+EE +L+HPA+ +AAA+ LPD++LGEKICAAV+F I+LAELN +LD Sbjct 416 RGGETVSASDIEEHILTHPAVSAAAAIALPDEFLGEKICAAVIFKSEQISLAELNRHLDE 475 Query 518 RGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLG 553 RGV+AH+RPD LVAMP+LP T +GK+DK+ IV Q+G Sbjct 476 RGVSAHSRPDMLVAMPSLPITAVGKVDKKQIVAQVG 511 >gi|169629333|ref|YP_001702982.1| bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase [Mycobacterium abscessus ATCC 19977] gi|169241300|emb|CAM62328.1| Bifunctional enzyme MbtA : salicyl-AMP ligase + salicyl-S-ArCP synthetase [Mycobacterium abscessus] Length=550 Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/536 (64%), Positives = 399/536 (75%), Gaps = 5/536 (0%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L GFVPFP+ RA YR AGYW+G T++++L +A R P AV D H LSY EL Sbjct 18 LDGFVPFPSVRADEYRRAGYWTGNTVESLLRVSAARRPCHPAVIDE-----HRALSYREL 72 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D+ AD AA A LGI PGDRVLLQLPN FAVALF L+RAGAIPVMCLPGHRAAEL H Sbjct 73 DEAADNAAHAFLRLGIAPGDRVLLQLPNRASFAVALFGLMRAGAIPVMCLPGHRAAELSH 132 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F V+ A GLV+ D A GFDYR +A L HP LR V+V+GD GPF SW L Sbjct 133 FIEVADAVGLVIPDSAGGFDYRALAVALSQRHPRLRTVVVEGDAGPFASWTSLLKSVEPQ 192 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P +PALLLVSGGTT PKLIPRTH+DYV+NAT +A +C L+ DDVYLV L AG Sbjct 193 GPLPTVQTDTPALLLVSGGTTAAPKLIPRTHEDYVYNATQAARVCGLTQDDVYLVALPAG 252 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HNFPLACPGLLGA++ GAT VF DPSPE+AFA I RH V+VTA+VP+LA+LWAQ+ WE Sbjct 253 HNFPLACPGLLGAISTGATTVFLSDPSPESAFATIARHRVSVTAVVPSLAQLWAQATAWE 312 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 PV P++LRLLQVGG+KL +DAR VR +LT GLQQVFGMAEGLL T+ GDP ++++++Q Sbjct 313 PVLPETLRLLQVGGAKLGADDARAVRESLTQGLQQVFGMAEGLLCLTQPGDPTDILDNSQ 372 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+C ADE+RIV+ DG V GE GELLVRGPYTLNGY+ A+ DN R F DGFYRSGD Sbjct 373 GRPMCDADEVRIVDEDGADVPAGETGELLVRGPYTLNGYYRADADNMRSFTVDGFYRSGD 432 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 VR G L VTGR+KDVI R GE+IAA DLE L +HPA+++AAAVGLPDQYLGE +C Sbjct 433 RVRALPGGYLEVTGRIKDVILRGGESIAALDLESHLQTHPAVYAAAAVGLPDQYLGEIVC 492 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 AA+VF G P+ AELN +L RG A H+R D+LVA+ ALP T +GKIDKRA++ L Sbjct 493 AAIVFKGKPVAAAELNQHLQARGAATHSRVDKLVAVSALPLTAVGKIDKRALLASL 548 >gi|226361743|ref|YP_002779521.1| 2,3-dihydroxybenzoate-AMP ligase [Rhodococcus opacus B4] gi|226240228|dbj|BAH50576.1| 2,3-dihydroxybenzoate-AMP ligase [Rhodococcus opacus B4] Length=535 Score = 565 bits (1455), Expect = 9e-159, Method: Compositional matrix adjust. Identities = 297/535 (56%), Positives = 358/535 (67%), Gaps = 9/535 (1%) Query 19 GFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQ 78 GFVPFP + YRA GYW G L +L AA RWP R A+ +YA+LD Sbjct 10 GFVPFPDADSDRYRACGYWRGEPLGDILRRAAHRWPQRPAIL------ADDTTTYAQLDS 63 Query 79 RADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFA 138 ADR A+ L +G PGDRV++QLPN +FAV F LLRA AIPV+CLP HR E+GH A Sbjct 64 AADRMASGLMRMGFAPGDRVVVQLPNVPEFAVVFFGLLRAAAIPVLCLPAHREREIGHLA 123 Query 139 AVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSP 198 A+S A G VVAD G+DYR +AR + A P++ HV+V GD F S A + A T Sbjct 124 ALSGAIGYVVADRVGGYDYRELARAVRAAAPSVEHVLVHGDAREFTSLASVPA---TVRE 180 Query 199 APPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHN 258 P DP A+LL+SGGTTG+PKLI RTHDDY +NA ASA +C L+ DDVYLV L A HN Sbjct 181 LPTVDPADVAVLLISGGTTGVPKLIARTHDDYAYNARASAEVCALTGDDVYLVALPAAHN 240 Query 259 FPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPV 318 FPLACPG+LG VG F DPSPE+AFAAIERH TVTA+VP LA+LW + EWE Sbjct 241 FPLACPGILGTFGVGGAVTFLADPSPESAFAAIERHRATVTAVVPPLAQLWCTATEWESA 300 Query 319 TPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGR 378 P SLRLLQVGG+KL AR VR L LQQVFGMAEGLLN+TR+ DP ++V +QGR Sbjct 301 DPGSLRLLQVGGAKLAENAAREVRPRLGAALQQVFGMAEGLLNYTRLDDPDDLVATSQGR 360 Query 379 PLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLV 438 PL DE+RIV+ G V G EGELL RGPYT+ GY+ A N R F DGFYRSGDLV Sbjct 361 PLSELDEVRIVDDAGNDVPAGTEGELLTRGPYTIRGYYRAAEHNARAFTADGFYRSGDLV 420 Query 439 RRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKICAA 498 RR G+LVVTGR+KDVI R GE+++A ++EE LL+HPA+ A +GLPD LGE++CAA Sbjct 421 RRLPSGHLVVTGRIKDVINRGGESVSAGEVEEHLLAHPAVVQVAVIGLPDDDLGERVCAA 480 Query 499 VVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLG 553 +V TLA+L +L RG+A PD L + LP T +GKIDKRA+ +G Sbjct 481 MVVDDTLPTLAQLKDFLTGRGLAPFKHPDLLHVVEHLPVTAVGKIDKRAVAADIG 535 >gi|54022587|ref|YP_116829.1| putative hydroxybenzoate-AMP ligase [Nocardia farcinica IFM 10152] gi|54014095|dbj|BAD55465.1| putative salicylate-AMP ligase [Nocardia farcinica IFM 10152] Length=536 Score = 563 bits (1451), Expect = 3e-158, Method: Compositional matrix adjust. Identities = 298/531 (57%), Positives = 363/531 (69%), Gaps = 10/531 (1%) Query 19 GFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAV-ADAGDRPGHGGLSYAELD 77 G+VPFPA+ A +YRAAGYW+GR L +L A P R A+ D G R YA +D Sbjct 10 GYVPFPAETAEAYRAAGYWTGRPLGDLLRATASAHPGRTALLTDDGAR------DYAWVD 63 Query 78 QRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHF 137 ADR A L LGI PGDRV++QLPN +F LF LLRAG IPV+ LP HR AE+ H Sbjct 64 AEADRMAHGLLALGIAPGDRVVVQLPNVPEFLTVLFGLLRAGIIPVLTLPAHRRAEIEHL 123 Query 138 AAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGS 197 A +S A ++AD FDYR +A + + P+LRHV+V GD GPF L A G Sbjct 124 ATLSEAVAYIIADRQGDFDYRELAATVCDNVPSLRHVLVLGDAGPFT---DLSGIARDGD 180 Query 198 PAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGH 257 P DP AL+LVSGGTTG+PKLI RTHDDYV+NATASA LC L+A+DVYL L A H Sbjct 181 SLPEIDPSDIALMLVSGGTTGLPKLIARTHDDYVYNATASAELCELTAEDVYLATLPAAH 240 Query 258 NFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEP 317 NFPLACPG+LG+++VGA F DPSPE AFA IERH VTVTA+VP LA+LW + EWE Sbjct 241 NFPLACPGILGSVSVGAAVAFVTDPSPENAFAVIERHRVTVTAVVPPLAQLWCAAVEWEE 300 Query 318 VTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQG 377 SLRLLQVGG++L +AR V AL LQQVFGMAEGLLN+TR+ DP +++ TQG Sbjct 301 ADLGSLRLLQVGGARLADVNAREVTPALGATLQQVFGMAEGLLNYTRLDDPEDLICTTQG 360 Query 378 RPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDL 437 RPL PADE+R+V+ +G V PGEEGELL RGPYT+ GY+ A N R F PDG+YRSGDL Sbjct 361 RPLSPADEVRVVDGEGNDVAPGEEGELLTRGPYTIRGYYRAPEHNARAFTPDGYYRSGDL 420 Query 438 VRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKICA 497 VR G+L+V+GR+KDVI R GE I+ +LEE LL++PA+ AAAVGLPD LGEK+CA Sbjct 421 VRVLPSGHLIVSGRIKDVINRGGENISCDELEEHLLAYPAVRHAAAVGLPDAALGEKVCA 480 Query 498 AVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAI 548 +V G +LAE+ +L RG+A PD L LP T +GKIDK+ + Sbjct 481 VLVVDGDMPSLAEVKKFLLGRGLATFKLPDVLRQADTLPLTAVGKIDKKVL 531 >gi|134099240|ref|YP_001104901.1| 2,3-dihydroxybenzoate-AMP ligase [Saccharopolyspora erythraea NRRL 2338] gi|291007146|ref|ZP_06565119.1| 2,3-dihydroxybenzoate-AMP ligase [Saccharopolyspora erythraea NRRL 2338] gi|133911863|emb|CAM01976.1| 2,3-dihydroxybenzoate-AMP ligase [Saccharopolyspora erythraea NRRL 2338] Length=554 Score = 523 bits (1346), Expect = 4e-146, Method: Compositional matrix adjust. Identities = 289/536 (54%), Positives = 351/536 (66%), Gaps = 6/536 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L GF P+P + A YR AG+W TL +L A R D AV A + LSYAEL Sbjct 7 LDGFTPWPGELADHYRNAGHWRDETLGGLLRTWAARSGDAPAVV-AENVGSARRLSYAEL 65 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D R D AA L LGI DRV++ LPN F V FALLR GA+PV+ LP HR +E+ H Sbjct 66 DGRVDATAAGLRALGIAARDRVVVHLPNTLDFVVVFFALLRCGAVPVLALPAHRQSEIEH 125 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F +S A VV D GFD+R +A ++ A P+LRHV+V GDPGPF + L AG+ Sbjct 126 FVTLSEAVAYVVPDEHEGFDFRGLAADVAAKAPSLRHVLVSGDPGPFTALDAL--PAGSA 183 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P ADPG A+LL+SGGTTG PKLIPRTH DY +NA ASA +C L++DDVYL L Sbjct 184 EPLPEADPGDVAVLLISGGTTGKPKLIPRTHRDYAYNARASAEVCALTSDDVYLASLPVA 243 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HNFPLACPGLLG + G T V +P PSP+ +ERH VTVTALVP + ++W W+ Sbjct 244 HNFPLACPGLLGVLGAGGTVVLSPSPSPDVGLRLVERHRVTVTALVPPMVRMWVDVAAWD 303 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SLRLLQVGG+KL+ AR+V AL LQQVFGMAEGLLN+TR+ DP E+V TQ Sbjct 304 THDRSSLRLLQVGGAKLDDGLARQVTPALGCRLQQVFGMAEGLLNYTRLDDPDELVFGTQ 363 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRPL P DE+R+V+ +G+PV PGE GEL RGPYTL GY+ N F PDGFYRSGD Sbjct 364 GRPLSPDDEVRVVDENGDPVAPGEVGELWTRGPYTLRGYYRVPEYNATSFTPDGFYRSGD 423 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LVR+ G+LVV GR KDVI R GE ++A+ LEE LL+HPAI A +GLPD +GE++C Sbjct 424 LVRQLPSGHLVVEGRRKDVINRGGENVSAATLEEHLLAHPAIAQVAVLGLPDDSVGERVC 483 Query 497 AAVVF---AGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIV 549 A VV AG L EL +L RG+A PD+LV ALP T +GKI+KR +V Sbjct 484 AVVVLAPDAGRAPKLKELRAFLIDRGLARFMYPDRLVVRDALPLTGVGKINKRELV 539 >gi|288922802|ref|ZP_06416969.1| AMP-dependent synthetase and ligase [Frankia sp. EUN1f] gi|288345845|gb|EFC80207.1| AMP-dependent synthetase and ligase [Frankia sp. EUN1f] Length=597 Score = 509 bits (1310), Expect = 6e-142, Method: Compositional matrix adjust. Identities = 282/565 (50%), Positives = 357/565 (64%), Gaps = 37/565 (6%) Query 19 GFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQ 78 G+ +PA+ Y+ AGYW RTLD +L + ARR A+ GDR +SYAELD+ Sbjct 37 GWNRWPAEFVERYQEAGYWGDRTLDELLREWARRSGPATALV-CGDRR----ISYAELDE 91 Query 79 RADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFA 138 D AA L LGI PGD +++ LPN +F + LFAL+R GAI ++ LP HR E+ HFA Sbjct 92 AVDDLAAGLASLGIGPGDHLVVHLPNRAEFVMTLFALMRRGAIGILALPAHRRVEIEHFA 151 Query 139 AVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSP 198 +++ A G V+AD GFDYR +AR++ P++RHV+V G+PGP+ L A + Sbjct 152 SLAGAVGYVIADRFEGFDYRELARQVTEAVPSVRHVLVAGEPGPYTGLDALAAAGRSARL 211 Query 199 A-----------------------------PPADPGSPALLLVSGGTTGMPKLIPRTHDD 229 A P DPG A+LL+SGGTTG PKLIPRTH D Sbjct 212 AAAPSSDATAADATAADATAADATAAGATVPGLDPGDIAVLLISGGTTGKPKLIPRTHRD 271 Query 230 YVFNATASAALCRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFA 289 Y +NA ASA +CRL+A DVYLV L A HNFPLACPG+LGA TVGA+AV A SP+A F Sbjct 272 YAYNARASAEVCRLTAADVYLVALPAAHNFPLACPGILGAFTVGASAVMALSSSPDAVFD 331 Query 290 AIERHGVTVTALVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGL 349 I R VT+TA VP LA+LW ++ WE SLRLLQVGG+KL+ ARR+ L G+ Sbjct 332 LISRERVTITAAVPPLARLWVEAAGWEGPDTTSLRLLQVGGAKLDEGLARRITPTLGAGV 391 Query 350 QQVFGMAEGLLNFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGP 409 QQVFGMAEGLLN+TR+ DP E V TQGRPL ADE+R+++ G V G+ GEL RGP Sbjct 392 QQVFGMAEGLLNYTRLDDPDETVFTTQGRPLAEADEVRVLDGSGYEVPAGQVGELWTRGP 451 Query 410 YTLNGYFAAERDNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLE 469 YT+ GY+ A N F DGF+R+GDLVR+ G+LVV GRVKDVI R GE ++A +LE Sbjct 452 YTIRGYYRAAAHNATVFGADGFFRTGDLVRQLPTGHLVVEGRVKDVINRGGENVSAGELE 511 Query 470 EQLLSHPAIFSAAAVGLPDQYLGEKICAAVVFA--GAPITLAELNGYLDRRGVAAHTRPD 527 E L +HPA+ A VGLPD +GE +CA VV A GAP L E+ YL RG+A PD Sbjct 512 EHLQTHPAVAQVAVVGLPDPDVGESVCAVVVAAPGGAP-RLKEIKNYLRDRGLARFMLPD 570 Query 528 QLVAMPALPTTPIGKIDKRAIVRQL 552 +L + P T +GKIDKR + ++L Sbjct 571 RLEVVDGFPYTAVGKIDKRELRKRL 595 >gi|269124635|ref|YP_003298005.1| AMP-dependent synthetase and ligase [Thermomonospora curvata DSM 43183] gi|268309593|gb|ACY95967.1| AMP-dependent synthetase and ligase [Thermomonospora curvata DSM 43183] Length=524 Score = 508 bits (1308), Expect = 1e-141, Method: Compositional matrix adjust. Identities = 277/537 (52%), Positives = 349/537 (65%), Gaps = 17/537 (3%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 + GF P+P + AA Y A GYW D VL + + PDR+A+ +R L+YAEL Sbjct 1 MEGFTPWPEELAARYIAEGYWG----DHVLGEVPQGDPDRVALVAGDER-----LTYAEL 51 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 ++R DR AA LH LGI GDRV+LQLPN F + AL+R GA PV+ LP HR +E+G+ Sbjct 52 ERRIDRTAAGLHRLGIRRGDRVVLQLPNTASFVIVFLALMRLGAPPVLALPAHRHSEIGY 111 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 ++ A ++ D +G+DYR +AR L + HVIVDG+ F A+L A Sbjct 112 LCELAEAKAYIIPDRHAGYDYRELARSLGG----VEHVIVDGEAAEFTPLAELDADP--- 164 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P DP L L+SGGTTG+PKLIPRTH DYV+N TASA +C ++ VYLVVL A Sbjct 165 IPLERPDPADVGLFLLSGGTTGLPKLIPRTHRDYVYNLTASAEVCGFTSGTVYLVVLPAA 224 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HNF LACPGLLG ++VG T V AP SP+AAF IER TV A+VP +A LW + W Sbjct 225 HNFALACPGLLGTLSVGGTVVLAPSGSPDAAFPLIERERATVCAVVPPIALLWLDAATWS 284 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL+LLQVGG+KL E A ++ L LQQVFGMAEGLLN+TR+ DPPE++E TQ Sbjct 285 EEDLSSLQLLQVGGAKLATEPASKIPGVLGCKLQQVFGMAEGLLNYTRLDDPPELIETTQ 344 Query 377 GRPLCPADELRIVNAD-GEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSG 435 GRPL PADE+R+V+ D GE V GE GELL RGPYTL GY+ A N R F DGFYR+G Sbjct 345 GRPLSPADEIRVVDPDTGEDVPEGEVGELLTRGPYTLRGYYKAPEHNARSFTADGFYRTG 404 Query 436 DLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKI 495 DLVRR G+LVV GR KD I R GE IAA +LE L++HPA+ AA VG+PD +GE+ Sbjct 405 DLVRRLPSGHLVVEGRHKDQINRGGEKIAAEELEGHLIAHPAVHDAAVVGVPDPVMGERT 464 Query 496 CAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 CA +V G P TL E+ +L RGVA + PD++ + A P TP+GKI K+A++ L Sbjct 465 CAFLVARGTPPTLREVKEFLRDRGVADYKWPDRIEVVDAFPRTPVGKISKKALLAML 521 >gi|115374171|ref|ZP_01461458.1| 2,3-dihydroxybenzoate-AMP ligase [Stigmatella aurantiaca DW4/3-1] gi|310820855|ref|YP_003953213.1| 2,3-dihydroxybenzoate-amp ligase [Stigmatella aurantiaca DW4/3-1] gi|115368838|gb|EAU67786.1| 2,3-dihydroxybenzoate-AMP ligase [Stigmatella aurantiaca DW4/3-1] gi|309393927|gb|ADO71386.1| 2,3-dihydroxybenzoate-AMP ligase [Stigmatella aurantiaca DW4/3-1] Length=544 Score = 498 bits (1283), Expect = 8e-139, Method: Compositional matrix adjust. Identities = 258/536 (49%), Positives = 338/536 (64%), Gaps = 7/536 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G P+P + AA YR AGYW G T +L + A+R DR A+ R SY E Sbjct 13 LPGCTPWPEEFAARYRQAGYWRGETFGQMLRERAQRHGDRTALVAGTQR-----WSYREF 67 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D+R DR A H LGI P DRV++QLPN +F +FAL R GA+PV LP HR+AE+ + Sbjct 68 DERTDRLVAGFHALGIKPRDRVVVQLPNIAEFFEVVFALFRLGALPVFALPAHRSAEINY 127 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F + A V+ D SGFDYR +A ++ P+LRHVIV G+ GPF +QL A G Sbjct 128 FCEFTEAVAYVIPDKHSGFDYRTLAEKVRGAVPSLRHVIVVGEAGPFTPLSQLYASPAAG 187 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P P A +SGG+TG+PKLIPRTHDDY+++ S +C L VYL L A Sbjct 188 LPGPA--PSDVAFFQLSGGSTGVPKLIPRTHDDYIYSLRGSVEICGLDETSVYLCALPAA 245 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HNFPL+ PG+LG + G TAV A PSP+ F IER VT+TALVP LA +W + + Sbjct 246 HNFPLSSPGVLGTLYAGGTAVLALHPSPDQTFPLIERERVTLTALVPPLAMIWLDAAKAR 305 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL++LQVGG++L E A+RVR L LQQV+GMAEGL+N+TR+ DP E++ TQ Sbjct 306 RHDLSSLKVLQVGGARLSAEAAQRVRPTLGCTLQQVYGMAEGLVNYTRLDDPEELIVATQ 365 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ P DE+RI++ DG V PGE G+LL RGPYT+ GY+ AE N R F DGFY +GD Sbjct 366 GRPISPDDEIRIIDEDGRDVAPGETGQLLTRGPYTIRGYYNAEAHNARAFTSDGFYCTGD 425 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LVR +G +VV GR KD I R G+ IAA ++E LL+HP++ AA + +PD +LGE+ C Sbjct 426 LVRVTPEGYMVVEGRAKDQINRGGDKIAAEEVENHLLAHPSVHDAAVISIPDPFLGERTC 485 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 A V+ AP T A L +L RG+AA+ PD++ + P T +GK+ K+A+ L Sbjct 486 AFVIPREAPPTAATLTSFLRERGLAAYKIPDRVEFVTTFPQTGVGKVSKKALRETL 541 >gi|111223560|ref|YP_714354.1| 2,3-dihydroxybenzoate-AMP ligase [Frankia alni ACN14a] gi|111151092|emb|CAJ62801.1| 2,3-dihydroxybenzoate-AMP ligase [Frankia alni ACN14a] Length=578 Score = 498 bits (1283), Expect = 9e-139, Method: Compositional matrix adjust. Identities = 288/567 (51%), Positives = 355/567 (63%), Gaps = 34/567 (5%) Query 15 GGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDR-----LAVADAGDRPGHG 69 G + G+V +P D A Y A GYW G L D R W +R VA RP Sbjct 18 GTVDGWVRWPDDVARRYVAEGYWEGGPL----GDRLRAWAERSGSATAVVAGPPSRPVR- 72 Query 70 GLSYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGH 129 LSYA+LD+ D A L LG+ PG+RVL+QLPN +F LFALLR GAIPV+ LP H Sbjct 73 -LSYADLDRAVDDLAVGLDRLGLAPGERVLVQLPNRVEFVTLLFALLRLGAIPVLALPAH 131 Query 130 RAAELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPF------ 183 R E+ H A ++ A + D GFD+R +A+E+VA P++RHV+V G+ G F Sbjct 132 RRVEIEHLARLAGAVAYAIPDTHEGFDHRTLAQEIVAAVPSVRHVLVAGEAGRFTGIDAV 191 Query 184 ---------------VSWAQLCAQAGTGSPAPPA-DPGSPALLLVSGGTTGMPKLIPRTH 227 V + + + +P PA DP A+LL+SGGTTG PKLIPRTH Sbjct 192 AAAGADARAAAAPTSVPSTSVPSTSVPSTPVLPAPDPAGVAVLLISGGTTGKPKLIPRTH 251 Query 228 DDYVFNATASAALCRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAA 287 DY +NA ASA LC L+A+DV L L A HNFPLACPG+LGA+ VGAT V AP PSPE Sbjct 252 WDYAYNAAASAGLCGLTAEDVCLAALPAAHNFPLACPGILGALGVGATVVLAPSPSPEIV 311 Query 288 FAAIERHGVTVTALVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTP 347 F + R VTVTALVPALA++ + EWE SLRLLQVGG++L+ E ARR+ L P Sbjct 312 FELLARERVTVTALVPALARILVDAAEWEKPDTSSLRLLQVGGARLDAELARRIPAVLGP 371 Query 348 GLQQVFGMAEGLLNFTRIGDPPEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVR 407 +QQVFGMAEGLLN+TR + E+ TQGRPL PADE+RIV+ DG V PGE GEL R Sbjct 372 RVQQVFGMAEGLLNYTRQDEDAELSFTTQGRPLAPADEIRIVDRDGADVAPGEIGELWTR 431 Query 408 GPYTLNGYFAAERDNERCFDPDGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASD 467 GPYT+ GY+ A N F PDGFYR+GDLVR GNLVV GR+KDVI R GE ++A++ Sbjct 432 GPYTVRGYYRAAEHNATAFSPDGFYRTGDLVRLTASGNLVVEGRIKDVINRGGENVSATE 491 Query 468 LEEQLLSHPAIFSAAAVGLPDQYLGEKICAAVVFA-GAPITLAELNGYLDRRGVAAHTRP 526 LEE LL+HPAI AA V D+ +GE + A VV GA +TL + YL RG+A P Sbjct 492 LEEHLLAHPAIAQAAVVAAADEQVGESVRAVVVLTPGAGLTLKVIKAYLRGRGLARFMLP 551 Query 527 DQLVAMPALPTTPIGKIDKRAIVRQLG 553 D L + LP TP+GKIDKR + R+LG Sbjct 552 DLLTVVDTLPLTPVGKIDKRELRRRLG 578 >gi|326383365|ref|ZP_08205052.1| AMP-dependent synthetase and ligase [Gordonia neofelifaecis NRRL B-59395] gi|326197771|gb|EGD54958.1| AMP-dependent synthetase and ligase [Gordonia neofelifaecis NRRL B-59395] Length=546 Score = 497 bits (1279), Expect = 2e-138, Method: Compositional matrix adjust. Identities = 285/537 (54%), Positives = 343/537 (64%), Gaps = 11/537 (2%) Query 19 GFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQ 78 GF P D A SYRAAG + R L + L+ A P AV D L+Y L Sbjct 11 GFAPHRPDLADSYRAAGVFDDRPLWSALAARAVSNPTDPAVTDGAT---GTTLTYRGLLD 67 Query 79 RADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFA 138 +DR AA G+ PGDRV+LQL N +FAV F LLRAG +PVM LP HR E+ H A Sbjct 68 ASDRRAAGFATAGLRPGDRVILQLHNSAEFAVTFFGLLRAGLVPVMTLPAHRITEIAHLA 127 Query 139 AVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSP 198 A S A V D+ GFDYR +A +L + P + H+ V GD G S+ L +G P Sbjct 128 AGSGARAYVCDDIRGGFDYRDLAADLRSRVPAVEHIFVTGDAG---SFRPLPEDSGDWHP 184 Query 199 APPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHN 258 P D PAL LVSGGTTG+PKLI RTH+DY FNA SAA+ L+A DVYL L A HN Sbjct 185 -PAVDADLPALFLVSGGTTGLPKLIARTHNDYAFNAVTSAAIAELTASDVYLAALPAAHN 243 Query 259 FPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPV 318 FPL CPGLLG + VG VF DPSP++AF IER+ VTVTALVPALA+LW + EWEP Sbjct 244 FPLCCPGLLGMIGVGGHTVFTQDPSPDSAFDVIERYRVTVTALVPALAQLWCAATEWEPA 303 Query 319 TPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGR 378 SLRLLQVGGSKL DA + A+ P +QQVFGMAEGL+ +TR+ DP ++V +QG Sbjct 304 DISSLRLLQVGGSKLAAPDAAAIDAAMGPVVQQVFGMAEGLICYTRLDDPRDLVHVSQGA 363 Query 379 PLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLV 438 P+ P DE+RIV+ DG PV GEEGEL VRGPYT+ GY+ A N R F DGFY SGDLV Sbjct 364 PMSPLDEVRIVDEDGAPVPDGEEGELQVRGPYTIRGYYRAPEHNLRSFTDDGFYASGDLV 423 Query 439 RRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKICAA 498 RR G+L VTGR+KD I RAGE +AA D+EE LL+HPAI AA +GLPD LGE ICA Sbjct 424 RRLPSGHLAVTGRIKDTIVRAGENVAADDVEEHLLAHPAIAHAAVIGLPDDALGELICAV 483 Query 499 VV---FAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 VV AP +L ++ +L RG+A+ PD+ A+ LP T +GKIDK A+ L Sbjct 484 VVPGRDTTAP-SLPDVRSFLADRGLASFKLPDRFHAIDELPVTSVGKIDKAALRTDL 539 >gi|11127897|gb|AAG31128.1|AF299336_5 MxcE [Stigmatella aurantiaca Sg a15] Length=543 Score = 496 bits (1278), Expect = 3e-138, Method: Compositional matrix adjust. Identities = 261/538 (49%), Positives = 340/538 (64%), Gaps = 12/538 (2%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G +P + AA YR AGYW G T +L + A+R DR AV R SY EL Sbjct 13 LPGCTAWPEEYAAHYRKAGYWRGETFGQMLRERAQRHGDRTAVVAGTQR-----WSYREL 67 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D+R DR A H LGI P DRV++QLPN +F +FAL R GA+PV LP HR+AE+ + Sbjct 68 DERTDRLVAGFHALGIKPRDRVVVQLPNTAEFFEVIFALFRLGALPVFALPAHRSAEINY 127 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F + A V+ D SGFDYR +A ++ + P LRHV+V G+ GPF S +QL A Sbjct 128 FCEFTEAVAYVIPDKHSGFDYRTLAEKVRSAVPGLRHVVVVGEAGPFTSLSQLYA----- 182 Query 197 SPA--PPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLA 254 SP P P A +SGG+TG+PKLIPRTHDDY+++ S +C+L VYL L Sbjct 183 SPVDLPGPIPSDVAFFQLSGGSTGVPKLIPRTHDDYIYSLRGSVEICQLDETTVYLCALP 242 Query 255 AGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCE 314 A HNFPL+ PG+LG + G TAV A PSP+ AF IER +T TALVP LA +W + + Sbjct 243 AAHNFPLSSPGVLGTLYAGGTAVMALHPSPDQAFPLIERERITFTALVPPLAMIWMDAAK 302 Query 315 WEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEH 374 SL++LQVGG++L E A+RVR L LQQV+GMAEGL+N+TR+ DP E+V Sbjct 303 ARRHDLSSLKVLQVGGARLSTEAAQRVRPTLGCALQQVYGMAEGLVNYTRLDDPDELVIA 362 Query 375 TQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRS 434 TQGRP+ P DE+RI++ DG V PGE G+LL RGPYT+ GY+ AE N R F DGFY + Sbjct 363 TQGRPISPDDEIRIIDEDGRDVAPGETGQLLTRGPYTIRGYYNAEAHNARAFTSDGFYCT 422 Query 435 GDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEK 494 GDLVR +G LVV GR KD I R G+ IAA ++E LL+HP++ AA + +PD +LGE+ Sbjct 423 GDLVRVTPEGYLVVEGRAKDQINRGGDKIAAEEVENHLLAHPSVHDAAVISIPDPFLGER 482 Query 495 ICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 CA V+ AP T A L +L RG+AA+ PD++ + P T +GK+ K+A+ L Sbjct 483 TCAFVIPREAPPTAATLTSFLRERGLAAYKIPDRVEFVATFPQTGVGKVSKKALRETL 540 >gi|338534899|ref|YP_004668233.1| 2,3-dihydroxybenzoate-AMP ligase [Myxococcus fulvus HW-1] gi|337260995|gb|AEI67155.1| 2,3-dihydroxybenzoate-AMP ligase [Myxococcus fulvus HW-1] Length=548 Score = 496 bits (1277), Expect = 4e-138, Method: Compositional matrix adjust. Identities = 259/526 (50%), Positives = 342/526 (66%), Gaps = 7/526 (1%) Query 23 FPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQRADR 82 +P D AA YRAAGYW G T +L + AR +R A+ AG+R L+YA LD R + Sbjct 12 WPEDYAARYRAAGYWRGETFGQLLHERARTHGERTALV-AGER----RLTYAALDARVSQ 66 Query 83 AAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAAVSA 142 AA H LGI DRV++QLPN +F +FAL R GA+PV LP HRA+E+G+F A + Sbjct 67 LAAGFHALGIQAKDRVVVQLPNVAEFFEVVFALFRLGALPVFALPAHRASEIGYFCAFTE 126 Query 143 ATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSPAPPA 202 A V+AD +GFDYR +A ++ A+ PTL+HVIV GD G F + L A A T P PA Sbjct 127 AVAYVIADKQAGFDYRALAEQVRANCPTLKHVIVAGDAGAFTPLSSLFA-APTELPPGPA 185 Query 203 DPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHNFPLA 262 P A +SGG+TG+PKLIPRTHDDY+++ S +C++ D VYL L A HNFPL+ Sbjct 186 -PSDVAFFQLSGGSTGVPKLIPRTHDDYIYSLRGSVDICQVDEDSVYLCALPAAHNFPLS 244 Query 263 CPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPVTPKS 322 PG+LG G TAV AP+PSP+ F IER VT+TA+VP LA +W + + S Sbjct 245 SPGVLGTFYAGGTAVLAPNPSPDTVFPLIERERVTLTAVVPPLAMVWMDAAKARQHQLAS 304 Query 323 LRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGRPLCP 382 L++LQVGG++L E ARRV+ L LQQVFGMAEGL+N+TR+ DP +V+ TQGRP+ P Sbjct 305 LKVLQVGGARLSDEAARRVKPTLGCTLQQVFGMAEGLVNYTRLDDPEDVIVSTQGRPISP 364 Query 383 ADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLVRRRD 442 DE+R+V+ DGE V PGE G+LL RGPYT+ GY+ AE N + F DGFY +GD+VR Sbjct 365 DDEIRVVDEDGEDVAPGETGQLLTRGPYTIRGYYKAEAHNAKAFTADGFYHTGDVVRVTP 424 Query 443 DGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKICAAVVFA 502 G LVV GR KD I R G+ +AA ++E LL+HP + AA V +PD +LGE+ CA V+ Sbjct 425 QGYLVVEGRAKDQINRGGDKVAAEEVENHLLAHPDVHDAAVVAVPDAFLGERTCAFVIAR 484 Query 503 GAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAI 548 G P L +L +RG+AA PD++ + P T +GK+ K+A+ Sbjct 485 GTPPAPKVLTAFLRQRGLAAFKIPDRVEFVETFPKTGVGKVSKKAL 530 >gi|317506252|ref|ZP_07964071.1| 2,3-dihydroxybenzoate-AMP ligase [Segniliparus rugosus ATCC BAA-974] gi|316255498|gb|EFV14749.1| 2,3-dihydroxybenzoate-AMP ligase [Segniliparus rugosus ATCC BAA-974] Length=518 Score = 494 bits (1273), Expect = 1e-137, Method: Compositional matrix adjust. Identities = 280/525 (54%), Positives = 341/525 (65%), Gaps = 37/525 (7%) Query 42 LDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQRADRAAAALHGLGITPGDRVLLQ 101 L +L+ AA RWPDR+AVA A DR L+Y EL+ A A L G+ PG++ LLQ Sbjct 16 LGALLTRAAERWPDRVAVAQA-DR----TLTYRELEDEARSFAMGLAAFGLEPGEKALLQ 70 Query 102 LPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAAVSAATGLVVADVASGFDYRPMA 161 +PN +F +ALF L AG +PVMCLPGHR AEL HF V A + R MA Sbjct 71 IPNSPEFLIALFGALTAGVVPVMCLPGHRDAELAHFTRVCGAV--------AHLTTRHMA 122 Query 162 RELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSPAPPADPGSPALLLVSGGTTGMPK 221 + LV+ P +R + D ++A+ ++ P DP SPALLLVSGGTTG+PK Sbjct 123 K-LVS--PPVRALTTDVVLAAGRAYAKNVSE-------PVLDPDSPALLLVSGGTTGLPK 172 Query 222 LIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHNFPLACPGLLGAMTVGATAVFAPD 281 LIPRTH DY++N +A+A +C LS DVYL L HNFPLACPG LGAM++G+ VFA D Sbjct 173 LIPRTHRDYLYNLSAAARVCELSESDVYLAALPVAHNFPLACPGALGAMSLGSAVVFAAD 232 Query 282 PSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRV 341 PSPEAAFAAIERH VTVTAL P LA LWA + EWEP SLRLLQVGG+KLE E A+ + Sbjct 233 PSPEAAFAAIERHRVTVTALTPPLAGLWASAAEWEPADLGSLRLLQVGGAKLEAERAKEI 292 Query 342 RTAL---------TPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGRPLCPADELRIVNAD 392 AL GLQQVFGMAEGL+ FTR DP E+V +QGRP+ DE+R+++ Sbjct 293 LPALGLDRASNAGRMGLQQVFGMAEGLVCFTRPDDPDELVFESQGRPMSDQDEVRLMDES 352 Query 393 GEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLVRRRDDGNLVVTGRV 452 G V GE GEL RGPYT+ GY+ A N R F PDGFYRSGDL RR G+LVV GR Sbjct 353 GAEVPDGEVGELETRGPYTIAGYYNAPEANARAFAPDGFYRSGDLARRLPSGHLVVVGRA 412 Query 453 KDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKICAAVVF-----AGAPIT 507 KDVI R GETI+A ++EE L +HP I AAAV PD++LGEKICAAVV P+ Sbjct 413 KDVINRGGETISAEEVEEHLHAHPEIDLAAAVPCPDEFLGEKICAAVVLRTGACESGPLD 472 Query 508 LAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 L L +L RG++A +PD L+ +P LP TP+GK+DKRAI QL Sbjct 473 LPRLRAFLAARGLSAEKQPDMLLQLPTLPMTPVGKVDKRAIAAQL 517 >gi|262200633|ref|YP_003271841.1| AMP-dependent synthetase and ligase [Gordonia bronchialis DSM 43247] gi|262083980|gb|ACY19948.1| AMP-dependent synthetase and ligase [Gordonia bronchialis DSM 43247] Length=562 Score = 493 bits (1270), Expect = 3e-137, Method: Compositional matrix adjust. Identities = 278/551 (51%), Positives = 341/551 (62%), Gaps = 13/551 (2%) Query 12 SPDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGL 71 +P GFVP PAD YRA G + L +L DAA PD A+ D G +P L Sbjct 10 TPTAVTTGFVPRPADFIDRYRARGCYLDAPLWQLLDDAATSSPDSPALTDPGAQPPRT-L 68 Query 72 SYAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRA 131 +YA L R A G+ PG RV++Q N + V +FAL+RAG +PVM LP HR Sbjct 69 TYAALLAATRRRAGGFLRAGLRPGQRVVVQQNNTAELVVNVFALMRAGLLPVMALPAHRR 128 Query 132 AELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCA 191 AE+ H A S A+ V D GFD+R +A +LV D +L HV +DGDPG F+ Sbjct 129 AEITHLARTSGASAYVTEDGRHGFDHRTLATDLVDDVESLAHVFIDGDPGGFLPLPD--- 185 Query 192 QAGTGSPAPPAD---PGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDV 248 G P AD PAL L+SGGTTG+PKLIPRTH+DY FNA SA + L DV Sbjct 186 --ADGVELPSADGIDANLPALFLISGGTTGLPKLIPRTHNDYSFNARRSAEIAGLVDTDV 243 Query 249 YLVVLAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKL 308 YLV L HNFPL CPG+LG ++ G V DPSP+AAF IE +GVTVTALVPALA++ Sbjct 244 YLVALPGAHNFPLCCPGMLGVISTGGHIVLGTDPSPDAAFDLIETYGVTVTALVPALAQV 303 Query 309 WAQSCEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDP 368 W + EWEP SLRLLQVGG+KL DA + AL +QQVFGMAEGL+ +TR+ DP Sbjct 304 WCAATEWEPADISSLRLLQVGGAKLAEPDAVALDAALGDVVQQVFGMAEGLICYTRLDDP 363 Query 369 PEVVEHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDP 428 E+V TQGRP+ DELR+V+ G V G EGELLVRGPYT+ GY+ A+ N R F Sbjct 364 RELVHTTQGRPMSDDDELRVVDESGVDVPVGTEGELLVRGPYTIRGYYRADDHNTRSFTD 423 Query 429 DGFYRSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPD 488 DGFYRSGD VR G++ VTGR+KD I RAGE +AA D+EE LL+HP+I A +GLPD Sbjct 424 DGFYRSGDRVRVLPSGHVAVTGRIKDTIVRAGENVAADDVEESLLAHPSIRQVAVIGLPD 483 Query 489 QYLGEKICAAVVFAGAPIT----LAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKID 544 LGE+ICA VV P + L L +L +GVA PDQ++ LP TP+GKID Sbjct 484 DSLGERICAVVVPTDGPKSPAADLRTLRTFLTDQGVAPFKLPDQVIVATRLPVTPVGKID 543 Query 545 KRAIVRQLGIA 555 KRA+V + A Sbjct 544 KRALVEEFTAA 554 >gi|312198336|ref|YP_004018397.1| AMP-dependent synthetase and ligase [Frankia sp. EuI1c] gi|311229672|gb|ADP82527.1| AMP-dependent synthetase and ligase [Frankia sp. EuI1c] Length=555 Score = 493 bits (1269), Expect = 4e-137, Method: Compositional matrix adjust. Identities = 284/542 (53%), Positives = 348/542 (65%), Gaps = 13/542 (2%) Query 20 FVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQR 79 +VP+P + A Y A GYW G +L L R W +R A A A G LSYA+LD+ Sbjct 19 WVPWPDEAADRYVAEGYWRGGSLGERL----RGWAERYATATA-LVAGPVRLSYADLDRA 73 Query 80 ADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAA 139 AD AA L G G+T GDRV++ LPN +F LFAL R GAIPV+ LP HR E+ H Sbjct 74 ADDLAAGLAGTGLTVGDRVVVHLPNRAEFVTLLFALCRLGAIPVLTLPAHRRVEIEHLTR 133 Query 140 VSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSW------AQLCAQA 193 +S A + D GFD+R +A+E+V P++R V+V G PGPF S Sbjct 134 LSGAVAYAIPDTHEGFDHRVLAQEIVTAVPSVRQVLVAGAPGPFTSLEALAAAGAAARAD 193 Query 194 GTGSPAPPA-DPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVV 252 GT P P A DP A+LL+SGGTTG PKLIPRTH DY +NA ASA LC L+A D YLV Sbjct 194 GTARPVPAAPDPAGVAVLLISGGTTGKPKLIPRTHWDYGYNAEASARLCGLTAADTYLVA 253 Query 253 LAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQS 312 L A HNFPLACPG+LGA+ VGAT V A PSPE AF I VTVTALVPALA++W + Sbjct 254 LPAAHNFPLACPGILGALGVGATVVLAASPSPETAFGLIGGERVTVTALVPALARIWVDA 313 Query 313 CEWEPVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVV 372 EWE SLRLLQVGG++L+ E ARR+ AL +QQVFGMAEGLLN+TR+ + E+ Sbjct 314 AEWERPDTSSLRLLQVGGARLDAELARRIPRALGAQVQQVFGMAEGLLNYTRLDEDDELA 373 Query 373 EHTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFY 432 TQGRPL ADE+R+V DG V G GEL RGPYT+ GY+ A N F PDGFY Sbjct 374 FTTQGRPLAAADEIRVVGPDGADVPAGAVGELWARGPYTIRGYYRAAEHNATAFSPDGFY 433 Query 433 RSGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLG 492 RSGDLVR GNLVV GR+KDV+ R GE ++A++LEE LL+HP+I AA + PD+ +G Sbjct 434 RSGDLVRLTPSGNLVVEGRIKDVVNRGGENVSATELEEHLLAHPSIAQAAVIAAPDEQVG 493 Query 493 EKICAAVV-FAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQ 551 E + A +V GA TL + +L RG+A PD L + ALP TP+GKIDKR + R+ Sbjct 494 ESVRAVIVPVPGAAPTLKAVKAFLRERGLARFMLPDLLTVLDALPLTPVGKIDKRELRRR 553 Query 552 LG 553 LG Sbjct 554 LG 555 >gi|41408276|ref|NP_961112.1| MbtA [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396632|gb|AAS04495.1| MbtA [Mycobacterium avium subsp. paratuberculosis K-10] Length=400 Score = 492 bits (1267), Expect = 7e-137, Method: Compositional matrix adjust. Identities = 258/333 (78%), Positives = 282/333 (85%), Gaps = 3/333 (0%) Query 13 PDGGLGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLS 72 P G L GFVPFPA+RAA+YRAAG W+GR LDT+L+DAARRWPDR AV DA G G S Sbjct 8 PAGVLDGFVPFPAERAAAYRAAGLWTGRALDTILTDAARRWPDRTAVLDAS---GGTGFS 64 Query 73 YAELDQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAA 132 YA LD++A+RAAA L GI PGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAA Sbjct 65 YAGLDEQANRAAAGLADAGIAPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAA 124 Query 133 ELGHFAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQ 192 ELGHFAA+S AT L++AD A+GFDYR MA L+ +H L HVIVDGDPGPF+SWAQLC + Sbjct 125 ELGHFAALSQATALLIADTAAGFDYRTMAAGLIEEHEALAHVIVDGDPGPFLSWAQLCER 184 Query 193 AGTGSPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVV 252 A G PA P DPGSPALLLVSGGTTG PKLIPRTH+DYVFNATASA LC L+ DDVYL V Sbjct 185 APAGRPATPVDPGSPALLLVSGGTTGTPKLIPRTHNDYVFNATASAELCGLTRDDVYLAV 244 Query 253 LAAGHNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQS 312 L+AGHNFPLACPGLLGAMTVGAT VF DPSPEAAFA I RHGVTVTALVPALAKLWAQ+ Sbjct 245 LSAGHNFPLACPGLLGAMTVGATTVFGTDPSPEAAFATIARHGVTVTALVPALAKLWAQA 304 Query 313 CEWEPVTPKSLRLLQVGGSKLEPEDARRVRTAL 345 CEWE PKSLRLLQVGG+KLE +DAR +R+AL Sbjct 305 CEWEDNPPKSLRLLQVGGAKLEADDARVIRSAL 337 >gi|229017675|ref|ZP_04174566.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus AH1273] gi|229023893|ref|ZP_04180376.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus AH1272] gi|228737406|gb|EEL87918.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus AH1272] gi|228743601|gb|EEL93710.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus AH1273] Length=538 Score = 490 bits (1262), Expect = 2e-136, Method: Compositional matrix adjust. Identities = 237/532 (45%), Positives = 333/532 (63%), Gaps = 8/532 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T ++L + A ++ D++AV G ++Y+EL Sbjct 2 LTGYTEWPEEFANRYREEGCWLGETFGSLLRERAEKYGDQIAVV-----SGDTHITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR AA L LG+ DRV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLAAGLLNLGVKQEDRVVIQLPNIIEFFEICFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ + L + Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVAGEEEEFVNISDLYIDS--- 173 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C L+A+ VY+ +L Sbjct 174 VPLPEVKPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLNAESVYMAILPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ AFA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL+++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NNDLSSLQVIQVGGAKFSAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLNDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ + V PGE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSTFDEVRVVDENDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNVRSFTKDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ A V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAI 548 A V+ G T++EL +L RG+AA+ PD++ + + P T +GK+ K+ + Sbjct 474 AFVIARGQAPTVSELKMFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKEL 525 >gi|108757791|ref|YP_631832.1| 2,3-dihydroxybenzoate-AMP ligase [Myxococcus xanthus DK 1622] gi|108461671|gb|ABF86856.1| 2,3-dihydroxybenzoate-AMP ligase [Myxococcus xanthus DK 1622] Length=548 Score = 490 bits (1261), Expect = 3e-136, Method: Compositional matrix adjust. Identities = 260/541 (49%), Positives = 342/541 (64%), Gaps = 7/541 (1%) Query 23 FPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQRADR 82 +P AA YR AGYW T +L + A+R +R A+ AG+R L+YA LD R + Sbjct 12 WPEAYAARYREAGYWRSETFGQLLHERAQRHGERTALV-AGER----RLTYANLDARVSQ 66 Query 83 AAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAAVSA 142 AA H LGI DRV++QLPN +F +FAL R GA+PV LP HRA+E+G+F A + Sbjct 67 LAAGFHALGIQARDRVVVQLPNVAEFFEVIFALFRLGALPVFALPAHRASEIGYFCAFTE 126 Query 143 ATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSPAPPA 202 A V+AD +GFDYR +A ++ PTL+HVIV GD GPF + + L A A T P PA Sbjct 127 AVAYVIADKQAGFDYRTLAEQVRGTCPTLKHVIVAGDAGPFTALSSLYA-APTALPPGPA 185 Query 203 DPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHNFPLA 262 P A +SGG+TG+PKLIPRTHDDY+++ S +C+L VYL L A HNFPL+ Sbjct 186 -PSDVAFFQLSGGSTGVPKLIPRTHDDYIYSLRGSVDICQLDETSVYLCALPAAHNFPLS 244 Query 263 CPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPVTPKS 322 PG+LG G TAV AP+ SP+ F IER VT+TA+VP LA +W + + S Sbjct 245 SPGVLGTFYAGGTAVLAPNSSPDTVFPIIERERVTITAVVPPLAMVWMDAAKTRRHQLAS 304 Query 323 LRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGRPLCP 382 LR+LQVGG++L E A RV+ L LQQVFGMAEGL+N+TR+ DP +V+ TQGRP+ P Sbjct 305 LRVLQVGGARLSTEAAMRVKPTLGCTLQQVFGMAEGLVNYTRLDDPEDVIVSTQGRPISP 364 Query 383 ADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLVRRRD 442 DE+R+V+ DGE V PGE G+LL RGPYT+ GY+ AE N + F DGFY +GD+VR Sbjct 365 DDEIRVVDEDGEDVAPGETGQLLTRGPYTIRGYYKAEAHNAKAFTDDGFYHTGDVVRVTP 424 Query 443 DGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKICAAVVFA 502 G LVV GR KD I R G+ +AA ++E LL+HP + AA V +PD +LGE+ CA V+ Sbjct 425 QGYLVVEGRAKDQINRGGDKVAAEEVENHLLAHPDVHDAAVVAVPDAFLGERTCAFVIAR 484 Query 503 GAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLGIATGPVTTQ 562 G P L +L +RG+AA PD++ + A P T +GK+ K+A+ L A P Sbjct 485 GTPPAPNVLTAFLRQRGLAAFKIPDRVEFVEAFPKTGVGKVSKKALRDVLAGAPSPTPVS 544 Query 563 R 563 R Sbjct 545 R 545 >gi|228945975|ref|ZP_04108317.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus thuringiensis serovar monterrey BGSC 4AJ1] gi|228813723|gb|EEM60002.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus thuringiensis serovar monterrey BGSC 4AJ1] Length=538 Score = 489 bits (1259), Expect = 6e-136, Method: Compositional matrix adjust. Identities = 244/547 (45%), Positives = 339/547 (62%), Gaps = 10/547 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T VL + A ++ D++AV G+ ++Y+EL Sbjct 2 LTGYTKWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVS-----GNTYITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR A+ L LGI P +RV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLASGLLNLGIKPENRVVIQLPNVIEFFEMCFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ + L Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEEEEFVNISDLYIDP--- 173 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C L+ D VY+ VL Sbjct 174 VPLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAGICNLNTDSVYMAVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ AFA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL ++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NNDLSSLEVIQVGGAKFSAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLNDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ + V PGE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSTFDEVRVVDENDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNARSFTKDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ G ++V GR KD I R GE +AA ++E LL+H A+ AA V +PD YLGE+ C Sbjct 414 LVKVNKQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDAAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLGIAT 556 A V+ G ++EL +L RG+AA+ PD++ + + P T +GK+ K+ + R++ IA Sbjct 474 AFVIARGQAPAVSELKMFLRERGIAAYKIPDRIEFIDSFPQTGVGKVSKKEL-RKV-IAE 531 Query 557 GPVTTQR 563 +T +R Sbjct 532 KLITVKR 538 >gi|196043674|ref|ZP_03110912.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus 03BB108] gi|196025983|gb|EDX64652.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus 03BB108] Length=538 Score = 488 bits (1256), Expect = 1e-135, Method: Compositional matrix adjust. Identities = 245/547 (45%), Positives = 337/547 (62%), Gaps = 10/547 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T VL + A ++ D++AV G+ ++Y+EL Sbjct 2 LTGYTKWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVS-----GNTYITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR A+ L LGI P DRV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLASGLLNLGIKPEDRVVIQLPNVIEFFEMCFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ + L Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEEEEFVNISDLYIDP--- 173 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C LSAD VY+ VL Sbjct 174 VLLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLSADSVYMAVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ FA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDETFALIEKEKVTITALVPPLAMIWLDAASLR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL ++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NNDLSSLEVIQVGGAKFSAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLNDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ V PGE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSALDEVRVVDEYDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNARSFTKDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ A V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLGIAT 556 A V+ G ++EL +L RG+AA+ PD++ + + P T +GK+ K+ + R++ IA Sbjct 474 AFVIARGQAPAVSELKRFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKEL-RKV-IAE 531 Query 557 GPVTTQR 563 VT +R Sbjct 532 KLVTVKR 538 >gi|229030073|ref|ZP_04186137.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus AH1271] gi|228731243|gb|EEL82161.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus AH1271] Length=538 Score = 488 bits (1255), Expect = 1e-135, Method: Compositional matrix adjust. Identities = 242/547 (45%), Positives = 339/547 (62%), Gaps = 10/547 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T +L + A ++ D++AV G+ ++Y+EL Sbjct 2 LTGYTKWPKEFADHYREEGCWLGETFGGMLRERAEKYGDQIAVV-----SGNTHITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR A+ L LGI DRV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLASGLLNLGIKQEDRVVIQLPNAIEFFEICFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ + L + Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEEEEFVNISDLYIDS--- 173 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C L+ D VY+ VL Sbjct 174 IPLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLNTDSVYMAVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ AFA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLANGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL ++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NNDLSSLEVIQVGGAKFGAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLNDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ + V GE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSTYDEVRVVDENDNDVKVGEVGSLLTRGPYTIRGYYKAEEHNARSFTEDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ A V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLGIAT 556 A V+ G T++EL +L RG+AA+ PD++ + + P T +GK+ K+ + R++ IA Sbjct 474 AFVIARGQAPTVSELKMFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKEL-RKV-IAE 531 Query 557 GPVTTQR 563 +T +R Sbjct 532 KLITVKR 538 >gi|228914959|ref|ZP_04078564.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus thuringiensis serovar pulsiensis BGSC 4CC1] gi|228844755|gb|EEM89801.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus thuringiensis serovar pulsiensis BGSC 4CC1] Length=538 Score = 487 bits (1254), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 240/532 (46%), Positives = 330/532 (63%), Gaps = 8/532 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T VL + A ++ D++AV G+ ++Y+EL Sbjct 2 LTGYTKWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVS-----GNTYITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR A+ L LGI P DRV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLASGLLNLGIKPEDRVVIQLPNVIEFFEMCFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ + L Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEKEEFVNISDLYIDP--- 173 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C LSA+ VY+ VL Sbjct 174 VPLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLSAESVYMAVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ AFA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL ++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NNDLSSLEVIQVGGAKFSAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ V PGE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSALDEVRVVDEYDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNARSFTKDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ A V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAI 548 A V+ G ++EL +L RG+AA+ PD++ + + P T +GK+ K+ + Sbjct 474 AFVIARGQAPAVSELKRFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKEL 525 >gi|301053889|ref|YP_003792100.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus biovar anthracis str. CI] gi|300376058|gb|ADK04962.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus biovar anthracis str. CI] Length=538 Score = 487 bits (1254), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 245/547 (45%), Positives = 338/547 (62%), Gaps = 10/547 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T VL + A ++ D++AV G+ ++Y+EL Sbjct 2 LTGYTKWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVS-----GNTYITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR A+ L LGI P DRV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLASGLLNLGIKPEDRVVIQLPNVIEFFEMCFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ + L Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEKEEFVNISDLYIDP--- 173 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C LSA+ VY+ VL Sbjct 174 VPLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLSAESVYMAVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ AFA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL ++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NNDLSSLEVIQVGGAKFSAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ V PGE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSALDEVRVVDEYDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNARSFTKDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ A V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLGIAT 556 A V+ G ++EL +L RG+AA+ PD++ + + P T +GK+ K+ + R++ IA Sbjct 474 AFVIARGQAPAVSELKRFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKEL-RKV-IAE 531 Query 557 GPVTTQR 563 V +R Sbjct 532 KLVMVKR 538 >gi|229091345|ref|ZP_04222560.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus Rock3-42] gi|228691974|gb|EEL45716.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus Rock3-42] Length=538 Score = 487 bits (1254), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 244/547 (45%), Positives = 339/547 (62%), Gaps = 10/547 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T VL + A ++ D++AV G+ ++Y+EL Sbjct 2 LTGYTKWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVS-----GNTYITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR A+ L LGI P +RV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLASGLLNLGIKPENRVVIQLPNVIEFFEMCFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ + L Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEKEEFVNISDLYIDP--- 173 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C LS + VY+ VL Sbjct 174 VPLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLSVESVYMAVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ AFA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL ++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NNDLSSLEVIQVGGAKFSAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ V PGE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSTLDEVRVVDEYDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNARSFTKDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ AA V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDAAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLGIAT 556 A V+ G ++EL +L RG+AA+ PD++ + + P T +GK+ K+ + R++ IA Sbjct 474 AFVIARGQAPAVSELKMFLRERGIAAYKIPDRIEFIDSFPQTGVGKVSKKEL-RKV-IAE 531 Query 557 GPVTTQR 563 +T +R Sbjct 532 KLITVKR 538 >gi|229060018|ref|ZP_04197389.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus AH603] gi|228719237|gb|EEL70845.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus AH603] Length=538 Score = 486 bits (1251), Expect = 4e-135, Method: Compositional matrix adjust. Identities = 236/532 (45%), Positives = 330/532 (63%), Gaps = 8/532 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T ++L + A ++ D++AV + ++Y+EL Sbjct 2 LIGYTEWPKEFANRYREEGCWLGETFGSMLKERAEKYGDQIAVVSSNTH-----ITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR A+ L LGI DRV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLASGLLNLGIKKEDRVVIQLPNIIEFFEICFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FVS +L Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEEEEFVSINELYMNP--- 173 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C L+A+ VY+ VL Sbjct 174 VPLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSADICNLNAESVYMAVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ +FA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDESFALIEKEKVTITALVPPLAMIWLDAASSR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL+++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NDDLSSLQVIQVGGAKFSAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLNDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ + V GE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSTFDEVRVVDENDNDVKLGEVGSLLTRGPYTIRGYYKAEEHNARSFTEDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ A V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAI 548 A V+ G +T EL +L RG+AA+ PD++ + + P T +GK+ K+ + Sbjct 474 AFVIARGQVLTANELKMFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKEL 525 >gi|30262375|ref|NP_844752.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus anthracis str. Ames] gi|47527665|ref|YP_019014.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus anthracis str. 'Ames Ancestor'] gi|49185215|ref|YP_028467.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus anthracis str. Sterne] 17 more sequence titles Length=538 Score = 486 bits (1251), Expect = 5e-135, Method: Compositional matrix adjust. Identities = 245/547 (45%), Positives = 338/547 (62%), Gaps = 10/547 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T VL + A ++ D++AV G+ ++Y+EL Sbjct 2 LTGYTKWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVS-----GNTYITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR A+ L LGI P DRV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLASGLLNLGIKPEDRVVIQLPNVIEFFEMCFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ + L Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEKEEFVNISDLYIDPVL- 175 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C LSA+ VY+ VL Sbjct 176 --LPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLSAESVYMAVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ AFA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWLDAASSR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL ++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NNDLSSLEVIQVGGAKFSAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ V PGE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSALDEVRVVDEYDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNARSFTNDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ A V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLGIAT 556 A V+ G ++EL +L RG+AA+ PD++ + + P T +GK+ K+ + R++ IA Sbjct 474 AFVIARGQAPAVSELKRFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKEL-RKV-IAE 531 Query 557 GPVTTQR 563 VT +R Sbjct 532 KLVTVKR 538 >gi|81681119|emb|CAJ34366.1| putative 3-hydroxy-quinaldate-AMP-Ligase [Micromonospora sp. ML1] Length=523 Score = 486 bits (1251), Expect = 5e-135, Method: Compositional matrix adjust. Identities = 259/525 (50%), Positives = 336/525 (64%), Gaps = 9/525 (1%) Query 21 VPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAELDQRA 80 +P+P + AA YR GYW GR L +L++A R D+ A+ G+R ++YAEL + + Sbjct 1 MPWPEELAALYRREGYWQGRPLGDLLTEACARHADKTALV-CGER----RMTYAELSRAS 55 Query 81 DRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGHFAAV 140 A L +GI P DRV++QLPN +F V ++ALLR GAIPVM LPGHR EL H A Sbjct 56 ADVAGGLLDVGIEPLDRVVVQLPNVPEFVVVVYALLRIGAIPVMALPGHRKVELTHLCAH 115 Query 141 SAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTGSPAP 200 S A LVV D GFD+R +ARE+ A+ P L+HV+V GD F + A L + G P Sbjct 116 SQAVALVVVDQVKGFDHRALAREVRAEVPALKHVVVAGDAEEFTALADLYRR---GRDLP 172 Query 201 PADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAGHNFP 260 DP PAL L+SGGTTG+PKLIPRTHDDY +N A+A R A+DVYL V GHN Sbjct 173 AVDPSEPALFLLSGGTTGLPKLIPRTHDDYAYNMRATADALRFGAEDVYLAVNPIGHNSA 232 Query 261 LACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWEPVTP 320 L CPG+LGA+ VG TAV P+ F +ER VT+T LVP + +LW + V Sbjct 233 LGCPGVLGALLVGGTAVLTSSVRPDEVFELLERERVTLTTLVPPVVRLWLDAARKSDVRF 292 Query 321 KSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQGRPL 380 +L +LQVG SK +P A VRT+L L Q FG+ EGLL +TR+ DP EVV T+GRPL Sbjct 293 PNL-MLQVGSSKFDPARAAEVRTSLGAVLTQWFGVGEGLLTYTRLDDPEEVVLATEGRPL 351 Query 381 CPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGDLVRR 440 DE+ +V+ DG PV G EGELLVRGPYT+ GY+ AE N R F PDG++R+GD+VRR Sbjct 352 AAHDEILVVDTDGRPVPDGAEGELLVRGPYTIRGYYRAEEQNRRSFTPDGYFRTGDMVRR 411 Query 441 RDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKICAAVV 500 R DG++VV GR+KD+I R GE + A ++EE LL+H AI AA VG+ D LGEK A V+ Sbjct 412 RPDGSIVVVGRIKDIINRGGEKVPAEEIEEHLLAHAAIRDAAVVGVADPVLGEKTVAFVI 471 Query 501 FAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDK 545 PI+ A + +L RG+A + PD++V + P T +GK+DK Sbjct 472 LRDEPISPAAVKSFLRERGLATYKIPDRVVPIEEFPRTAVGKVDK 516 >gi|72162270|ref|YP_289927.1| 2,3-dihydroxybenzoate-AMP ligase [Thermobifida fusca YX] gi|71916002|gb|AAZ55904.1| 2,3-dihydroxybenzoate-AMP ligase [Thermobifida fusca YX] Length=543 Score = 486 bits (1250), Expect = 6e-135, Method: Compositional matrix adjust. Identities = 258/539 (48%), Positives = 338/539 (63%), Gaps = 8/539 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G P+PA+ A YR AGYW+G T ++D RR+ DRLAV AG R +YAEL Sbjct 2 LDGCTPWPAEFAVRYREAGYWTGETFSDFVTDRTRRFADRLAVVGAGQR-----WTYAEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 +R+ A L LGI GDRV++QLPN + +FAL R GA+PV LP HRA E+ H Sbjct 57 GERSAVLATGLARLGIAAGDRVVVQLPNIPELFEVVFALFRLGALPVYALPAHRAHEITH 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 + A L++ D +GFDYR MA +L HV+V G+PG F A+L A Sbjct 117 LCTTAQAKALIIPDRHAGFDYRTMAAQLRHAGTAPEHVVVVGEPGGFTPLAELRADRPDP 176 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 + A L +SGGTTG+PKLIPRTHDDY+++ ASA +C L D VYL L A Sbjct 177 GVFTRPEASDAAFLQLSGGTTGLPKLIPRTHDDYLYSVRASAEICALGTDTVYLAALPAV 236 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HNFP++ PG LG G T V AP+PSP+ AF+ IE VT+TA+VP +A W + E Sbjct 237 HNFPMSSPGFLGTFHAGGTVVLAPNPSPDTAFSLIETERVTITAVVPPIALQWLDAVEHG 296 Query 317 PVTPK---SLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVE 373 + + SLR+LQVGG+K PE ARRVR L LQQVFGMAEGL+N+TR+ DP +++ Sbjct 297 SQSHRDLSSLRVLQVGGAKFAPEAARRVRPVLGCTLQQVFGMAEGLVNYTRLDDPDDIIT 356 Query 374 HTQGRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYR 433 TQGRP+ P DE+RIV+ PV GE G LL RGPYT+ GY+ AE N F PDGFYR Sbjct 357 TTQGRPISPDDEIRIVDEADRPVPDGEVGHLLTRGPYTIRGYYRAEEHNATAFTPDGFYR 416 Query 434 SGDLVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGE 493 +GDLVRR G+LVV GR KD I R GE ++A ++E +L+HPA+ AA VG+ D YLGE Sbjct 417 TGDLVRRTPTGHLVVEGRAKDQINRGGEKVSAEEVENHILAHPAVHDAAVVGMSDPYLGE 476 Query 494 KICAAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQL 552 ++CA V+ P + +EL +L RG+A++ PD++ + P T +GKI + + R+L Sbjct 477 RVCAYVIARTEPPSRSELLRFLRERGLASYKIPDRVEFVDRFPVTGVGKISRSELRREL 535 >gi|167639615|ref|ZP_02397885.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus anthracis str. A0193] gi|177649419|ref|ZP_02932421.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus anthracis str. A0174] gi|254737395|ref|ZP_05195099.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus anthracis str. Western North America USA6153] gi|167512324|gb|EDR87700.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus anthracis str. A0193] gi|172084493|gb|EDT69551.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus anthracis str. A0174] Length=538 Score = 486 bits (1250), Expect = 6e-135, Method: Compositional matrix adjust. Identities = 245/547 (45%), Positives = 338/547 (62%), Gaps = 10/547 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T VL + A ++ D++AV G+ ++Y+EL Sbjct 2 LTGYTKWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVS-----GNTYITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR A+ L LGI P DRV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLASGLLNLGIKPEDRVVIQLPNVIEFFEMCFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ + L Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEKEEFVNISDLYIDPVL- 175 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C LSA+ VY+ VL Sbjct 176 --LPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLSAESVYMAVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ AFA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDEAFALIEKEKVTITALVPPLAMIWIDAASSR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL ++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NNDLSSLEVIQVGGAKFSAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ V PGE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSALDEVRVVDEYDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNARSFTNDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ A V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAIVRQLGIAT 556 A V+ G ++EL +L RG+AA+ PD++ + + P T +GK+ K+ + R++ IA Sbjct 474 AFVIARGQAPAVSELKRFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKEL-RKV-IAE 531 Query 557 GPVTTQR 563 VT +R Sbjct 532 KLVTVKR 538 >gi|52143109|ref|YP_083720.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus E33L] gi|51976578|gb|AAU18128.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus cereus E33L] Length=538 Score = 486 bits (1250), Expect = 6e-135, Method: Compositional matrix adjust. Identities = 239/532 (45%), Positives = 329/532 (62%), Gaps = 8/532 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR G W G T VL + A ++ D++AV G+ ++Y+EL Sbjct 2 LTGYTKWPKEFADRYREEGCWLGETFGGVLRERAEKYGDQIAVVS-----GNTYITYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR A+ L LGI P DRV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLASGLLNLGIKPEDRVVIQLPNVIEFFEMCFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ + L Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVQEKVPTLQHVIVVGEEEEFVNISDLYIDP--- 173 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C LSA+ VY+ VL Sbjct 174 VPLPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLSAESVYMAVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ FA IE+ VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDETFALIEKEKVTITALVPPLAMIWLDAASLR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL ++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NNDLSSLEVIQVGGAKFSVEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ V PGE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSALDEVRVVDEYDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNARSFTNDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ A V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAI 548 A V+ G ++EL +L RG+AA+ PD++ + + P T +GK+ K+ + Sbjct 474 AFVIARGQAPAVSELKRFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKEL 525 >gi|228965341|ref|ZP_04126433.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus thuringiensis serovar sotto str. T04001] gi|228794331|gb|EEM41845.1| 2,3-dihydroxybenzoate-AMP ligase [Bacillus thuringiensis serovar sotto str. T04001] Length=538 Score = 485 bits (1249), Expect = 7e-135, Method: Compositional matrix adjust. Identities = 240/532 (46%), Positives = 329/532 (62%), Gaps = 8/532 (1%) Query 17 LGGFVPFPADRAASYRAAGYWSGRTLDTVLSDAARRWPDRLAVADAGDRPGHGGLSYAEL 76 L G+ +P + A YR AG W G T VL + A ++ D++AV G ++Y+EL Sbjct 2 LVGYTEWPKEFADRYREAGCWLGETFGGVLRERAEKYGDQIAVV-----SGKTHVTYSEL 56 Query 77 DQRADRAAAALHGLGITPGDRVLLQLPNGCQFAVALFALLRAGAIPVMCLPGHRAAELGH 136 D++ DR AA L LGI DRV++QLPN +F FAL R GA+PV LP HR++E+ + Sbjct 57 DKKVDRLAAGLLNLGIKKEDRVVIQLPNIIEFFEICFALFRIGALPVFALPSHRSSEISY 116 Query 137 FAAVSAATGLVVADVASGFDYRPMARELVADHPTLRHVIVDGDPGPFVSWAQLCAQAGTG 196 F A+ V++D A GFDYR +ARE+ PTL+HVIV G+ FV+ L + Sbjct 117 FCEFGEASAYVISDKALGFDYRKLAREVKEKVPTLQHVIVVGEEEEFVNINDLYMDPIS- 175 Query 197 SPAPPADPGSPALLLVSGGTTGMPKLIPRTHDDYVFNATASAALCRLSADDVYLVVLAAG 256 P P A L +SGGTTG+ KLIPRTHDDY+++ SA +C L+A+ VY+ VL Sbjct 176 --LPEVQPSDVAFLQLSGGTTGLSKLIPRTHDDYIYSLRVSAEICNLNAESVYMTVLPVA 233 Query 257 HNFPLACPGLLGAMTVGATAVFAPDPSPEAAFAAIERHGVTVTALVPALAKLWAQSCEWE 316 HN+P++ PG G G V A SP+ AFA IE VT+TALVP LA +W + Sbjct 234 HNYPMSSPGTFGTFYAGGKVVLATGGSPDEAFALIEEEKVTITALVPPLAMIWLDAASSR 293 Query 317 PVTPKSLRLLQVGGSKLEPEDARRVRTALTPGLQQVFGMAEGLLNFTRIGDPPEVVEHTQ 376 SL ++QVGG+K E A+R+R LQQVFGMAEGL+N+TR+ DP E++ HTQ Sbjct 294 NADLSSLEVIQVGGAKFSAEVAKRIRPTFGCTLQQVFGMAEGLVNYTRLDDPEEIIIHTQ 353 Query 377 GRPLCPADELRIVNADGEPVGPGEEGELLVRGPYTLNGYFAAERDNERCFDPDGFYRSGD 436 GRP+ DE+R+V+ + V PGE G LL RGPYT+ GY+ AE N R F DGFYR+GD Sbjct 354 GRPMSAHDEVRVVDENDNDVKPGEVGSLLTRGPYTIRGYYKAEEHNARSFTKDGFYRTGD 413 Query 437 LVRRRDDGNLVVTGRVKDVICRAGETIAASDLEEQLLSHPAIFSAAAVGLPDQYLGEKIC 496 LV+ + G ++V GR KD I R GE +AA ++E LL+H A+ A V +PD YLGE+ C Sbjct 414 LVKVNEQGYIIVEGRDKDQINRGGEKVAAEEVENHLLAHDAVHDVAIVSMPDDYLGERTC 473 Query 497 AAVVFAGAPITLAELNGYLDRRGVAAHTRPDQLVAMPALPTTPIGKIDKRAI 548 A V+ G T++EL +L RG+AA+ PD++ + + P T +GK+ K+ + Sbjct 474 AFVIARGQVPTVSELKMFLRERGIAAYKIPDRIEFIESFPQTGVGKVSKKEL 525 Lambda K H 0.320 0.138 0.425 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1264862876760 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40