BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2388c

Length=375
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|289553823|ref|ZP_06443033.1|  oxygen-independent coproporphyri...   749    0.0   
gi|15841901|ref|NP_336938.1|  coproporphyrinogen III oxidase [Myc...   749    0.0   
gi|15609525|ref|NP_216904.1|  coproporphyrinogen III oxidase [Myc...   749    0.0   
gi|289448030|ref|ZP_06437774.1|  oxygen-independent coproporphyri...   748    0.0   
gi|31793565|ref|NP_856058.1|  coproporphyrinogen III oxidase [Myc...   748    0.0   
gi|340627399|ref|YP_004745851.1|  putative oxygen-independent cop...   745    0.0   
gi|240169937|ref|ZP_04748596.1|  coproporphyrinogen III oxidase [...   649    0.0   
gi|183983689|ref|YP_001851980.1|  oxygen-independent coproporphyr...   616    2e-174
gi|118618922|ref|YP_907254.1|  coproporphyrinogen III oxidase [My...   616    2e-174
gi|342857790|ref|ZP_08714446.1|  coproporphyrinogen III oxidase [...   611    5e-173
gi|254822300|ref|ZP_05227301.1|  coproporphyrinogen III oxidase [...   609    3e-172
gi|339295287|gb|AEJ47398.1|  coproporphyrinogen III oxidase [Myco...   593    1e-167
gi|296170555|ref|ZP_06852139.1|  coproporphyrinogen dehydrogenase...   588    7e-166
gi|118463403|ref|YP_881013.1|  coproporphyrinogen III oxidase [My...   586    2e-165
gi|41408305|ref|NP_961141.1|  coproporphyrinogen III oxidase [Myc...   584    8e-165
gi|333990162|ref|YP_004522776.1|  oxygen-independent coproporphyr...   543    1e-152
gi|145223274|ref|YP_001133952.1|  coproporphyrinogen III oxidase ...   540    1e-151
gi|315443734|ref|YP_004076613.1|  coproporphyrinogen III oxidase ...   540    1e-151
gi|120404813|ref|YP_954642.1|  coproporphyrinogen III oxidase [My...   539    3e-151
gi|118473719|ref|YP_888797.1|  coproporphyrinogen III oxidase [My...   531    9e-149
gi|108800439|ref|YP_640636.1|  coproporphyrinogen III oxidase [My...   500    2e-139
gi|126436063|ref|YP_001071754.1|  coproporphyrinogen III oxidase ...   497    1e-138
gi|169628753|ref|YP_001702402.1|  coproporphyrinogen III oxidase ...   485    5e-135
gi|308404907|ref|ZP_07494180.2|  HemN C- region superfamily [Myco...   484    9e-135
gi|226360384|ref|YP_002778162.1|  coproporphyrinogen III oxidase ...   482    5e-134
gi|111018259|ref|YP_701231.1|  coproporphyrinogen III oxidase [Rh...   478    9e-133
gi|229493209|ref|ZP_04387001.1|  putative oxygen-independent copr...   476    2e-132
gi|226307231|ref|YP_002767191.1|  coproporphyrinogen III oxidase ...   473    3e-131
gi|325677129|ref|ZP_08156798.1|  coproporphyrinogen dehydrogenase...   464    1e-128
gi|312140297|ref|YP_004007633.1|  oxygen-independent coproporphyr...   461    9e-128
gi|326381607|ref|ZP_08203301.1|  coproporphyrinogen III oxidase [...   452    6e-125
gi|333918863|ref|YP_004492444.1|  Coproporphyrinogen dehydrogenas...   451    8e-125
gi|324998261|ref|ZP_08119373.1|  coproporphyrinogen III oxidase, ...   451    9e-125
gi|296140464|ref|YP_003647707.1|  oxygen-independent coproporphyr...   450    2e-124
gi|343926586|ref|ZP_08766088.1|  oxygen-independent coproporphyri...   447    1e-123
gi|302528865|ref|ZP_07281207.1|  coproporphyrinogen III oxidase [...   447    2e-123
gi|257055326|ref|YP_003133158.1|  coproporphyrinogen III oxidase,...   445    6e-123
gi|54023388|ref|YP_117630.1|  coproporphyrinogen III oxidase [Noc...   439    3e-121
gi|317508577|ref|ZP_07966238.1|  HemN protein [Segniliparus rugos...   437    1e-120
gi|62391133|ref|YP_226535.1|  coproporphyrinogen III oxidase [Cor...   436    4e-120
gi|300788491|ref|YP_003768782.1|  oxygen-independent coproporphyr...   435    6e-120
gi|344044709|gb|EGV40385.1|  coproporphyrinogen III oxidase [Cory...   435    7e-120
gi|262203055|ref|YP_003274263.1|  oxygen-independent coproporphyr...   432    4e-119
gi|227833636|ref|YP_002835343.1|  oxygen-independent coproporphyr...   429    4e-118
gi|256375378|ref|YP_003099038.1|  coproporphyrinogen III oxidase ...   425    6e-117
gi|25028747|ref|NP_738801.1|  coproporphyrinogen III oxidase [Cor...   421    1e-115
gi|259507808|ref|ZP_05750708.1|  oxygen-independent coproporphyri...   421    1e-115
gi|134098063|ref|YP_001103724.1|  coproporphyrinogen III oxidase ...   420    2e-115
gi|38234293|ref|NP_940060.1|  coproporphyrinogen III oxidase [Cor...   419    3e-115
gi|213965780|ref|ZP_03393972.1|  putative oxygen-independent copr...   419    3e-115


>gi|289553823|ref|ZP_06443033.1| oxygen-independent coproporphyrinogen III oxidase hemN [Mycobacterium 
tuberculosis KZN 605]
 gi|289438455|gb|EFD20948.1| oxygen-independent coproporphyrinogen III oxidase hemN [Mycobacterium 
tuberculosis KZN 605]
Length=381

 Score =  749 bits (1935),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 375/375 (100%), Positives = 375/375 (100%), Gaps = 0/375 (0%)

Query  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  60
            MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV
Sbjct  7    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  66

Query  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120
            HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT
Sbjct  67   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  126

Query  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180
            RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS
Sbjct  127  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  186

Query  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240
            VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW
Sbjct  187  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  246

Query  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP
Sbjct  247  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  306

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360
            VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG
Sbjct  307  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  366

Query  361  RGRLLADAVVRTLLG  375
            RGRLLADAVVRTLLG
Sbjct  367  RGRLLADAVVRTLLG  381


>gi|15841901|ref|NP_336938.1| coproporphyrinogen III oxidase [Mycobacterium tuberculosis CDC1551]
 gi|148823590|ref|YP_001288344.1| coproporphyrinogen III oxidase [Mycobacterium tuberculosis F11]
 gi|167968733|ref|ZP_02551010.1| coproporphyrinogen III oxidase [Mycobacterium tuberculosis H37Ra]
 38 more sequence titles
 Length=390

 Score =  749 bits (1935),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 375/375 (100%), Positives = 375/375 (100%), Gaps = 0/375 (0%)

Query  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  60
            MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV
Sbjct  16   MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  75

Query  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120
            HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT
Sbjct  76   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  135

Query  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180
            RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS
Sbjct  136  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  195

Query  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240
            VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW
Sbjct  196  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  255

Query  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP
Sbjct  256  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  315

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360
            VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG
Sbjct  316  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  375

Query  361  RGRLLADAVVRTLLG  375
            RGRLLADAVVRTLLG
Sbjct  376  RGRLLADAVVRTLLG  390


>gi|15609525|ref|NP_216904.1| coproporphyrinogen III oxidase [Mycobacterium tuberculosis H37Rv]
 gi|148662221|ref|YP_001283744.1| coproporphyrinogen III oxidase [Mycobacterium tuberculosis H37Ra]
 gi|289443910|ref|ZP_06433654.1| oxygen-independent coproporphyrinogen III oxidase [Mycobacterium 
tuberculosis T46]
 22 more sequence titles
 Length=375

 Score =  749 bits (1933),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 375/375 (100%), Positives = 375/375 (100%), Gaps = 0/375 (0%)

Query  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  60
            MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV
Sbjct  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  60

Query  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120
            HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT
Sbjct  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120

Query  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180
            RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS
Sbjct  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180

Query  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240
            VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW
Sbjct  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240

Query  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP
Sbjct  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360
            VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG
Sbjct  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360

Query  361  RGRLLADAVVRTLLG  375
            RGRLLADAVVRTLLG
Sbjct  361  RGRLLADAVVRTLLG  375


>gi|289448030|ref|ZP_06437774.1| oxygen-independent coproporphyrinogen III oxidase hemN [Mycobacterium 
tuberculosis CPHL_A]
 gi|289420988|gb|EFD18189.1| oxygen-independent coproporphyrinogen III oxidase hemN [Mycobacterium 
tuberculosis CPHL_A]
Length=375

 Score =  748 bits (1932),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 374/375 (99%), Positives = 374/375 (99%), Gaps = 0/375 (0%)

Query  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  60
            MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV
Sbjct  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  60

Query  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120
            HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT
Sbjct  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120

Query  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180
            RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS
Sbjct  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180

Query  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240
            VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW
Sbjct  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240

Query  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP
Sbjct  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360
            VAGFEQLGADALHTEDVLLKVRLRQGLP ARLGAAERERAEAVLADGLLDYHGDRLVLTG
Sbjct  301  VAGFEQLGADALHTEDVLLKVRLRQGLPFARLGAAERERAEAVLADGLLDYHGDRLVLTG  360

Query  361  RGRLLADAVVRTLLG  375
            RGRLLADAVVRTLLG
Sbjct  361  RGRLLADAVVRTLLG  375


>gi|31793565|ref|NP_856058.1| coproporphyrinogen III oxidase [Mycobacterium bovis AF2122/97]
 gi|121638267|ref|YP_978491.1| coproporphyrinogen III oxidase [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|224990761|ref|YP_002645448.1| coproporphyrinogen III oxidase [Mycobacterium bovis BCG str. 
Tokyo 172]
 gi|31619158|emb|CAD97270.1| PROBABLE OXYGEN-INDEPENDENT COPROPORPHYRINOGEN III OXIDASE HEMN 
(COPROPORPHYRINOGENASE) (COPROGEN OXIDASE) [Mycobacterium 
bovis AF2122/97]
 gi|121493915|emb|CAL72390.1| Probable oxygen-independent coproporphyrinogen III oxidase hemN 
[Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224773874|dbj|BAH26680.1| coproporphyrinogen III oxidase [Mycobacterium bovis BCG str. 
Tokyo 172]
 gi|341602305|emb|CCC64979.1| probable oxygen-independent coproporphyrinogen III oxidase hemN 
[Mycobacterium bovis BCG str. Moreau RDJ]
Length=375

 Score =  748 bits (1930),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 374/375 (99%), Positives = 374/375 (99%), Gaps = 0/375 (0%)

Query  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  60
            MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV
Sbjct  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  60

Query  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120
            HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT
Sbjct  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120

Query  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180
            RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS
Sbjct  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180

Query  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240
            VDA VQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW
Sbjct  181  VDATVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240

Query  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP
Sbjct  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360
            VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG
Sbjct  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360

Query  361  RGRLLADAVVRTLLG  375
            RGRLLADAVVRTLLG
Sbjct  361  RGRLLADAVVRTLLG  375


>gi|340627399|ref|YP_004745851.1| putative oxygen-independent coproporphyrinogen III oxidase [Mycobacterium 
canettii CIPT 140010059]
 gi|340005589|emb|CCC44751.1| putative oxygen-independent coproporphyrinogen III oxidase HEMN 
(coproporphyrinogenase) (coprogen oxidase) [Mycobacterium 
canettii CIPT 140010059]
Length=375

 Score =  745 bits (1923),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 372/375 (99%), Positives = 374/375 (99%), Gaps = 0/375 (0%)

Query  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  60
            MPGQPFGVYLHVPFCLTRCGYCDFNTYTPA+LGGVSPDRWLLALRAELELAAAKLDAPTV
Sbjct  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAELGGVSPDRWLLALRAELELAAAKLDAPTV  60

Query  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120
            HTVYVGGGTPSLLGGERLA LLDMVRDHFVLAPDAEV+TEANPESTWPEFFATIRAAGYT
Sbjct  61   HTVYVGGGTPSLLGGERLAMLLDMVRDHFVLAPDAEVTTEANPESTWPEFFATIRAAGYT  120

Query  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180
            RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS
Sbjct  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180

Query  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240
            VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW
Sbjct  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240

Query  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP
Sbjct  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360
            VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG
Sbjct  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360

Query  361  RGRLLADAVVRTLLG  375
            RGRLLADAVVRTLLG
Sbjct  361  RGRLLADAVVRTLLG  375


>gi|240169937|ref|ZP_04748596.1| coproporphyrinogen III oxidase [Mycobacterium kansasii ATCC 12478]
Length=378

 Score =  649 bits (1675),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 319/374 (86%), Positives = 344/374 (92%), Gaps = 0/374 (0%)

Query  2    PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVH  61
            PGQPFG+Y+HVPFC+TRCGYCDFNTYTPA+LGGV+PD WLLAL  ELELAAA+LDAPT++
Sbjct  5    PGQPFGLYVHVPFCVTRCGYCDFNTYTPAELGGVNPDAWLLALGTELELAAARLDAPTLN  64

Query  62   TVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTR  121
            TV+VGGGTPSLLGGERL  LL MVRD F LAPDAE++TEANPESTWPEFF  IRAAGYTR
Sbjct  65   TVFVGGGTPSLLGGERLTRLLGMVRDCFALAPDAEITTEANPESTWPEFFDAIRAAGYTR  124

Query  122  VSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSV  181
            VSLGMQSVAPRVLATLDRVHSPGRA+AAA EA+  GF HVNLDLIYGTPGESDDDL+RSV
Sbjct  125  VSLGMQSVAPRVLATLDRVHSPGRASAAAREAMDAGFEHVNLDLIYGTPGESDDDLLRSV  184

Query  182  DAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY  241
             AA+ AGVDHVSAYALVVE GTALARRVRRGEL+APD DVLAHRYEL DARL+AAG  WY
Sbjct  185  AAAIDAGVDHVSAYALVVEDGTALARRVRRGELSAPDGDVLAHRYELADARLTAAGLRWY  244

Query  242  EVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPV  301
            EVSNW RPGGECRHNLGYWDGGQWWGAGPGAHGY+G TRWWNVKHPN YAE++AGATLPV
Sbjct  245  EVSNWARPGGECRHNLGYWDGGQWWGAGPGAHGYVGATRWWNVKHPNAYAELVAGATLPV  304

Query  302  AGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGR  361
            AGFEQLGADALHTEDVLLK+RLRQGLP++RL +AERERA+ VLADGLL   GDRLVLT R
Sbjct  305  AGFEQLGADALHTEDVLLKIRLRQGLPMSRLDSAERERAKVVLADGLLATEGDRLVLTDR  364

Query  362  GRLLADAVVRTLLG  375
            GRLLADAVVRTLLG
Sbjct  365  GRLLADAVVRTLLG  378


>gi|183983689|ref|YP_001851980.1| oxygen-independent coproporphyrinogen III oxidase HemN [Mycobacterium 
marinum M]
 gi|183177015|gb|ACC42125.1| oxygen-independent coproporphyrinogen III oxidase HemN [Mycobacterium 
marinum M]
Length=390

 Score =  616 bits (1589),  Expect = 2e-174, Method: Compositional matrix adjust.
 Identities = 310/374 (83%), Positives = 344/374 (92%), Gaps = 0/374 (0%)

Query  2    PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVH  61
            PG+PFG+YLHVPFC+TRCGYCDFNTYTPA+LGGV+PD WLLALR+ELELAAA+L+APTV+
Sbjct  17   PGRPFGLYLHVPFCVTRCGYCDFNTYTPAELGGVNPDAWLLALRSELELAAARLNAPTVN  76

Query  62   TVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTR  121
            TV+VGGGTPSLLGG+RL TLLDMVRDHFVLAPD E++TEANPESTWPEFF  IR+AGYTR
Sbjct  77   TVFVGGGTPSLLGGQRLTTLLDMVRDHFVLAPDVEITTEANPESTWPEFFDAIRSAGYTR  136

Query  122  VSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSV  181
            VSLGMQSVAPRVLATLDRVHSPGRA+AAA EA A GF HVNLDLIYGTPGE+DDDL+RSV
Sbjct  137  VSLGMQSVAPRVLATLDRVHSPGRASAAAREAFAAGFEHVNLDLIYGTPGETDDDLLRSV  196

Query  182  DAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY  241
            DAA++AGVDHVSAYALVVE GTA+ARRVR+GEL   D+DVLAHRYEL DARL+AAG AWY
Sbjct  197  DAAIEAGVDHVSAYALVVEDGTAMARRVRQGELPPVDNDVLAHRYELADARLTAAGLAWY  256

Query  242  EVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPV  301
            EVSNW RPGGECRHNLGYW+GGQWWGAGPGAHGY+G TRWWNVKHPNTYAEILAG++LPV
Sbjct  257  EVSNWARPGGECRHNLGYWNGGQWWGAGPGAHGYVGATRWWNVKHPNTYAEILAGSSLPV  316

Query  302  AGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGR  361
            AG E+L  DALHTE+V+L +RLRQGLPLA L A ERERA+A +ADGLL   GD +VLT R
Sbjct  317  AGLERLEEDALHTEEVMLGLRLRQGLPLAHLDAGERERAQAAVADGLLTAEGDSVVLTDR  376

Query  362  GRLLADAVVRTLLG  375
            GRLLADAVVRTLLG
Sbjct  377  GRLLADAVVRTLLG  390


>gi|118618922|ref|YP_907254.1| coproporphyrinogen III oxidase [Mycobacterium ulcerans Agy99]
 gi|118571032|gb|ABL05783.1| oxygen-independent coproporphyrinogen III oxidase HemN [Mycobacterium 
ulcerans Agy99]
Length=390

 Score =  616 bits (1588),  Expect = 2e-174, Method: Compositional matrix adjust.
 Identities = 309/374 (83%), Positives = 344/374 (92%), Gaps = 0/374 (0%)

Query  2    PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVH  61
            PG+PFG+YLHVPFC+TRCGYCDFNTYTPA+LGGV+PD WLLALR+ELELAAA+L+APTV+
Sbjct  17   PGRPFGLYLHVPFCVTRCGYCDFNTYTPAELGGVNPDAWLLALRSELELAAARLNAPTVN  76

Query  62   TVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTR  121
            TV+VGGGTPSLLGG+RL TLLDMVRDHFVLAPD E++TEANPESTWPEFF  IR+AGYTR
Sbjct  77   TVFVGGGTPSLLGGQRLTTLLDMVRDHFVLAPDVEITTEANPESTWPEFFDAIRSAGYTR  136

Query  122  VSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSV  181
            VSLGMQSVAPRVLATLDRVHSPGRA+AAA EA A GF HVNLDLIYGTPGE+DDDL+RS+
Sbjct  137  VSLGMQSVAPRVLATLDRVHSPGRASAAAREAFAAGFEHVNLDLIYGTPGETDDDLLRSI  196

Query  182  DAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY  241
            DAA++AGVDHVSAYALVVE GTA+ARRVR+GEL   D+DVLAHRYEL DARL+AAG AWY
Sbjct  197  DAAIEAGVDHVSAYALVVEDGTAMARRVRQGELPPVDNDVLAHRYELADARLTAAGLAWY  256

Query  242  EVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPV  301
            EVSNW RPGGECRHNLGYW+GGQWWGAGPGAHGY+G TRWWNVKHPNTYAEILAG++LPV
Sbjct  257  EVSNWARPGGECRHNLGYWNGGQWWGAGPGAHGYVGATRWWNVKHPNTYAEILAGSSLPV  316

Query  302  AGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGR  361
            AG E+L  DALHTE+V+L +RLRQGLPLA L A ERERA+A +ADGLL   GD +VLT R
Sbjct  317  AGLERLEEDALHTEEVMLGLRLRQGLPLAHLDAGERERAQAAVADGLLTAEGDSVVLTDR  376

Query  362  GRLLADAVVRTLLG  375
            GRLLADAVVRTLLG
Sbjct  377  GRLLADAVVRTLLG  390


>gi|342857790|ref|ZP_08714446.1| coproporphyrinogen III oxidase [Mycobacterium colombiense CECT 
3035]
 gi|342135123|gb|EGT88289.1| coproporphyrinogen III oxidase [Mycobacterium colombiense CECT 
3035]
Length=390

 Score =  611 bits (1576),  Expect = 5e-173, Method: Compositional matrix adjust.
 Identities = 305/373 (82%), Positives = 331/373 (89%), Gaps = 0/373 (0%)

Query  3    GQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHT  62
            GQPFG+Y+HVPFC+TRCGYCDFNTYTPA+LGGV+PD WL AL  ELELAAA+L AP V T
Sbjct  18   GQPFGIYVHVPFCVTRCGYCDFNTYTPAELGGVNPDAWLSALGTELELAAARLQAPPVST  77

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLGG+R+ATLL MVR HF LAPDAEV+TEANPES WP+FF  IRAAGYTRV
Sbjct  78   VFVGGGTPSLLGGQRMATLLGMVRQHFTLAPDAEVTTEANPESAWPDFFDAIRAAGYTRV  137

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQSVAPRVL  LDR+H+P R+AAAA EA+A GF HV+LDLIYGTPGESDDDL+ SVD
Sbjct  138  SLGMQSVAPRVLGVLDRIHTPNRSAAAAREALAAGFEHVSLDLIYGTPGESDDDLLCSVD  197

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
             A++ GVDHVSAYALVVE GTALARRVRRGELAAPDDDVLAHRYELVDARLS AG +WYE
Sbjct  198  TAIETGVDHVSAYALVVEEGTALARRVRRGELAAPDDDVLAHRYELVDARLSQAGLSWYE  257

Query  243  VSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVA  302
            VSNW RPGGECRHNLGYWDGGQWWGAGPGAHGY+G TRWWNVKHPN YAE L+ A LPVA
Sbjct  258  VSNWSRPGGECRHNLGYWDGGQWWGAGPGAHGYLGATRWWNVKHPNAYAERLSAAALPVA  317

Query  303  GFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRG  362
            GFEQL +DALHTEDVLLK RLRQGLP+  L +AERERAE  +ADGLL   GDRLVLT RG
Sbjct  318  GFEQLDSDALHTEDVLLKTRLRQGLPVELLSSAERERAEGAVADGLLVSEGDRLVLTPRG  377

Query  363  RLLADAVVRTLLG  375
            RLLADAVVRTLLG
Sbjct  378  RLLADAVVRTLLG  390


>gi|254822300|ref|ZP_05227301.1| coproporphyrinogen III oxidase [Mycobacterium intracellulare 
ATCC 13950]
Length=390

 Score =  609 bits (1570),  Expect = 3e-172, Method: Compositional matrix adjust.
 Identities = 304/373 (82%), Positives = 329/373 (89%), Gaps = 0/373 (0%)

Query  3    GQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHT  62
            GQPFG+Y+HVPFC+TRCGYCDFNTYTPA+LGGV+PD WL ALRAELELAAA+L AP V T
Sbjct  18   GQPFGIYVHVPFCVTRCGYCDFNTYTPAELGGVNPDAWLGALRAELELAAARLQAPPVST  77

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLGG RL TLLDMVR+HF LA DAE++TEANPES WP+ F  IRAAGYTRV
Sbjct  78   VFVGGGTPSLLGGARLVTLLDMVREHFPLAADAEITTEANPESAWPDLFDAIRAAGYTRV  137

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQSVAPRVL  LDR+H+P R+A AA EA+A GF HV+LDLIYGTPGESDDDL+RSVD
Sbjct  138  SLGMQSVAPRVLGVLDRIHTPNRSADAAREALAAGFEHVSLDLIYGTPGESDDDLLRSVD  197

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
             A++ GVDHVSAYALVVE GTALARRVRRGELAAPDDDVLAHRYELVDARLS AG +WYE
Sbjct  198  TAIETGVDHVSAYALVVEEGTALARRVRRGELAAPDDDVLAHRYELVDARLSEAGMSWYE  257

Query  243  VSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVA  302
            VSNW RPGGECRHNLGYWDGGQWWGAGPGAHGY+G TRWWNVKHPN YAE L  A LPVA
Sbjct  258  VSNWSRPGGECRHNLGYWDGGQWWGAGPGAHGYVGTTRWWNVKHPNAYAERLGAAALPVA  317

Query  303  GFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRG  362
            GFE+L AD LHTEDVLLKVRLRQGLP+  L + ERERA  V+ADGLL   GDRLVLT RG
Sbjct  318  GFERLDADTLHTEDVLLKVRLRQGLPVGLLNSEERERAAGVVADGLLVTTGDRLVLTDRG  377

Query  363  RLLADAVVRTLLG  375
            RLLADAVVRTLLG
Sbjct  378  RLLADAVVRTLLG  390


>gi|339295287|gb|AEJ47398.1| coproporphyrinogen III oxidase [Mycobacterium tuberculosis CCDC5079]
Length=312

 Score =  593 bits (1530),  Expect = 1e-167, Method: Compositional matrix adjust.
 Identities = 300/302 (99%), Positives = 300/302 (99%), Gaps = 0/302 (0%)

Query  74   GGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRV  133
            GG  LATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRV
Sbjct  11   GGSSLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRV  70

Query  134  LATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVDHVS  193
            LATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVDHVS
Sbjct  71   LATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVDHVS  130

Query  194  AYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVSNWCRPGGEC  253
            AYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVSNWCRPGGEC
Sbjct  131  AYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVSNWCRPGGEC  190

Query  254  RHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGADALH  313
            RHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGADALH
Sbjct  191  RHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGADALH  250

Query  314  TEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTL  373
            TEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTL
Sbjct  251  TEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTL  310

Query  374  LG  375
            LG
Sbjct  311  LG  312


>gi|296170555|ref|ZP_06852139.1| coproporphyrinogen dehydrogenase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295894787|gb|EFG74512.1| coproporphyrinogen dehydrogenase [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=390

 Score =  588 bits (1515),  Expect = 7e-166, Method: Compositional matrix adjust.
 Identities = 293/375 (79%), Positives = 322/375 (86%), Gaps = 0/375 (0%)

Query  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTV  60
            +PG+PFGVY+HVPFC+TRCGYCDFNTYTPA+LGGV+PD WL ALR EL+LAA +L  PTV
Sbjct  16   VPGRPFGVYIHVPFCITRCGYCDFNTYTPAELGGVNPDAWLAALRTELQLAAERLAGPTV  75

Query  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120
             TV+VGGGTPSLLGG R+A+LLDMVR+HF LAPDAE++TEANPES WP+FF   RAAGYT
Sbjct  76   DTVFVGGGTPSLLGGARVASLLDMVREHFALAPDAEITTEANPESAWPDFFDAARAAGYT  135

Query  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180
            RVSLGMQSV+P VL  LDR+H+P R+AAAA EA+  GF HV+LDLIYGTPGESDDDL+RS
Sbjct  136  RVSLGMQSVSPTVLGVLDRIHTPNRSAAAAREALDAGFEHVSLDLIYGTPGESDDDLLRS  195

Query  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240
            +D AV+ GVDHVSAYALVVE GTALARRVRRGELAAPDDDVLAHRYELVDARLS AG  W
Sbjct  196  LDTAVETGVDHVSAYALVVEEGTALARRVRRGELAAPDDDVLAHRYELVDARLSEAGLTW  255

Query  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            YEVSNW RPGGECRHNLGYWDGGQWWGAGPGAHG++G  RWWNVKHPN YAE+LA A LP
Sbjct  256  YEVSNWSRPGGECRHNLGYWDGGQWWGAGPGAHGHVGAVRWWNVKHPNAYAEMLARAALP  315

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360
            V GFE L  DALHTE VLLK RLRQGLP   L  AER RAE  +ADGLL    DR VLT 
Sbjct  316  VGGFELLDPDALHTEVVLLKTRLRQGLPHDVLNPAERRRAEGAVADGLLVSADDRFVLTP  375

Query  361  RGRLLADAVVRTLLG  375
            RGRLLADAVVRT+LG
Sbjct  376  RGRLLADAVVRTVLG  390


>gi|118463403|ref|YP_881013.1| coproporphyrinogen III oxidase [Mycobacterium avium 104]
 gi|254774606|ref|ZP_05216122.1| coproporphyrinogen III oxidase [Mycobacterium avium subsp. avium 
ATCC 25291]
 gi|118164690|gb|ABK65587.1| putative oxygen-independent coproporphyrinogen III oxidase [Mycobacterium 
avium 104]
Length=390

 Score =  586 bits (1510),  Expect = 2e-165, Method: Compositional matrix adjust.
 Identities = 300/373 (81%), Positives = 331/373 (89%), Gaps = 0/373 (0%)

Query  3    GQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHT  62
            G+PFG+Y+HVPFC+TRCGYCDFNTYTPA+LGGV+PD WL ALR ELELAAA+L  P V+T
Sbjct  18   GRPFGLYVHVPFCVTRCGYCDFNTYTPAELGGVNPDAWLGALRTELELAAARLRPPPVNT  77

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLGG RLA LLDMVR+HF LAPDAE++TEANPESTWPEFF  IRAAGYTRV
Sbjct  78   VFVGGGTPSLLGGARLALLLDMVREHFALAPDAEITTEANPESTWPEFFDAIRAAGYTRV  137

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQSVAPRVL  LDR+H+P R+A AA EA+A GF HV+LDLIYGTPGESD+DL+ S+D
Sbjct  138  SLGMQSVAPRVLGVLDRIHTPNRSADAAREALAAGFEHVSLDLIYGTPGESDEDLLWSLD  197

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
             A++ GVDHVSAYALVVE GTALARRVRRGELAAPDDDVLAHRYELVDARLS AG +WYE
Sbjct  198  TAIETGVDHVSAYALVVEEGTALARRVRRGELAAPDDDVLAHRYELVDARLSQAGLSWYE  257

Query  243  VSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVA  302
            VSNW RPGG+CRHNLGYWDGGQWWGAGPGAHGY+G TRWWNVKHPN YAE L  A LPVA
Sbjct  258  VSNWSRPGGQCRHNLGYWDGGQWWGAGPGAHGYVGTTRWWNVKHPNAYAERLNAAALPVA  317

Query  303  GFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRG  362
            GFEQLG++ALHTEDVLLK+RLRQGLP+  L  AERER + V+ADGLL   GDRLVLT RG
Sbjct  318  GFEQLGSEALHTEDVLLKIRLRQGLPVDLLNPAERERVQGVVADGLLVRDGDRLVLTPRG  377

Query  363  RLLADAVVRTLLG  375
            RLLAD VVRTLLG
Sbjct  378  RLLADGVVRTLLG  390


>gi|41408305|ref|NP_961141.1| coproporphyrinogen III oxidase [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41396661|gb|AAS04524.1| HemN [Mycobacterium avium subsp. paratuberculosis K-10]
Length=390

 Score =  584 bits (1506),  Expect = 8e-165, Method: Compositional matrix adjust.
 Identities = 299/373 (81%), Positives = 331/373 (89%), Gaps = 0/373 (0%)

Query  3    GQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHT  62
            G PFG+Y+HVPFC+TRCGYCDFNTYTPA+LGGV+PD WL ALR ELELAAA+L  P V+T
Sbjct  18   GHPFGLYVHVPFCVTRCGYCDFNTYTPAELGGVNPDAWLGALRTELELAAARLRPPPVNT  77

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLGG RLA LLDMVR+HF LAPDAE++TEANPESTWPEFF  I AAGYTRV
Sbjct  78   VFVGGGTPSLLGGARLALLLDMVREHFALAPDAEITTEANPESTWPEFFDAIGAAGYTRV  137

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQSVAPRVL  LDR+H+P R+A AA EA+A GF HV+LDLIYGTPGESD+DL+ S+D
Sbjct  138  SLGMQSVAPRVLGVLDRIHTPNRSADAAREALAAGFEHVSLDLIYGTPGESDEDLLWSLD  197

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
             A+++GVDHVSAYALVVE GTALARRVRRGELAAPDDDVLAHRYELVDARLS AG +WYE
Sbjct  198  TAIESGVDHVSAYALVVEEGTALARRVRRGELAAPDDDVLAHRYELVDARLSQAGLSWYE  257

Query  243  VSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVA  302
            VSNW RPGG+CRHNLGYWDGGQWWGAGPGAHGY+G TRWWNVKHPN YAE L  A LPVA
Sbjct  258  VSNWSRPGGQCRHNLGYWDGGQWWGAGPGAHGYVGTTRWWNVKHPNAYAERLNAAALPVA  317

Query  303  GFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRG  362
            GFEQLG++ALHTEDVLLK+RLRQG P+  L +AERERA+ V+ADGLL   GDRLVLT RG
Sbjct  318  GFEQLGSEALHTEDVLLKIRLRQGFPVDLLNSAERERAQGVVADGLLVRDGDRLVLTPRG  377

Query  363  RLLADAVVRTLLG  375
            RLLAD VVRTLLG
Sbjct  378  RLLADGVVRTLLG  390


>gi|333990162|ref|YP_004522776.1| oxygen-independent coproporphyrinogen III oxidase HemN [Mycobacterium 
sp. JDM601]
 gi|333486130|gb|AEF35522.1| oxygen-independent coproporphyrinogen III oxidase HemN [Mycobacterium 
sp. JDM601]
Length=392

 Score =  543 bits (1400),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 272/371 (74%), Positives = 310/371 (84%), Gaps = 0/371 (0%)

Query  5    PFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVY  64
            PFGVY+HVPFC TRCGYCDFNTYTPA+LGG +PD W+ AL  ELELAAA+L  P   TV+
Sbjct  22   PFGVYVHVPFCFTRCGYCDFNTYTPAELGGANPDAWVAALARELELAAARLGGPRADTVF  81

Query  65   VGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSL  124
            VGGGTPSLLG  RLA +LD VR+HF L+ DAEV+TEANPEST PEFF +I AAGYTRVSL
Sbjct  82   VGGGTPSLLGSARLAAVLDHVREHFGLSDDAEVTTEANPESTSPEFFESILAAGYTRVSL  141

Query  125  GMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAA  184
            GMQSV+PRVLATLDR+HSPGR  AAA EA A GF H+N+DLIYGTPGE+DDDL+RSVDAA
Sbjct  142  GMQSVSPRVLATLDRIHSPGRPVAAAREASAAGFEHLNIDLIYGTPGETDDDLLRSVDAA  201

Query  185  VQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVS  244
            ++AGVDHVSAY+L+VE GTALARRVRRGEL  PD+DV+AHRYELVD+RL AAG  WYEVS
Sbjct  202  LEAGVDHVSAYSLIVEDGTALARRVRRGELPVPDNDVMAHRYELVDSRLRAAGMDWYEVS  261

Query  245  NWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGF  304
            NW R G  CRHNLGYW GG+WWGAGPGAHGY G  R+WNVKHPN YA++L   TLP+AGF
Sbjct  262  NWGRAGAACRHNLGYWSGGRWWGAGPGAHGYDGTLRFWNVKHPNAYAQLLGEMTLPIAGF  321

Query  305  EQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRL  364
            E+L     HTE+V+L +R+R+GL LA L   ERERAE+ + DGLL   GDRLVLT RGRL
Sbjct  322  EELSEADRHTEEVMLGLRMREGLALAVLDPGERERAESAVDDGLLCVDGDRLVLTDRGRL  381

Query  365  LADAVVRTLLG  375
            LADAVVR+LLG
Sbjct  382  LADAVVRSLLG  392


>gi|145223274|ref|YP_001133952.1| coproporphyrinogen III oxidase [Mycobacterium gilvum PYR-GCK]
 gi|145215760|gb|ABP45164.1| coproporphyrinogen III oxidase, anaerobic [Mycobacterium gilvum 
PYR-GCK]
Length=398

 Score =  540 bits (1392),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 272/374 (73%), Positives = 298/374 (80%), Gaps = 3/374 (0%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLG--GVSPDRWLLALRAELELAAAKL-DAPTV  60
            +PFGVY+HVPFC TRCGYCDFNTYTPA+LG  G +PD WL ALRAEL++AAA L + P V
Sbjct  24   RPFGVYIHVPFCATRCGYCDFNTYTPAELGAGGATPDGWLTALRAELQMAAAHLGEPPPV  83

Query  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120
             TV+VGGGTPSLLG   LA +LD VR  F L PDAE++TE+NPEST P FFA +RAAGYT
Sbjct  84   STVFVGGGTPSLLGAAGLARVLDAVRADFTLTPDAEITTESNPESTSPRFFAGLRAAGYT  143

Query  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180
            RVSLGMQS AP VL  LDRVHSPGRA  AA EA AEGF HVNLDLIYGTPGE+DDDL+RS
Sbjct  144  RVSLGMQSTAPHVLRALDRVHSPGRAVDAAREARAEGFDHVNLDLIYGTPGETDDDLLRS  203

Query  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240
             DAAV+AGVDHVS YAL+VE GTALARRVRRGE+A PDDDV A RYEL+D RL+ AGF W
Sbjct  204  ADAAVEAGVDHVSGYALIVEDGTALARRVRRGEIARPDDDVHARRYELLDCRLTDAGFTW  263

Query  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            YEVSNW RP GECRHNLGYWDGGQWWGAGPGAHGY+  TRWWNVKHPN YA  L    LP
Sbjct  264  YEVSNWSRPDGECRHNLGYWDGGQWWGAGPGAHGYVDATRWWNVKHPNAYAATLETGALP  323

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360
            VA  E + A+  H E+V+LK RLR GLP A L A ERERA   +ADGLL   G   VLT 
Sbjct  324  VADLEAIDAETSHVEEVMLKTRLRTGLPAATLSARERERAAVAVADGLLRADGQSFVLTD  383

Query  361  RGRLLADAVVRTLL  374
            RGRLLADAVVR LL
Sbjct  384  RGRLLADAVVRDLL  397


>gi|315443734|ref|YP_004076613.1| coproporphyrinogen III oxidase anaerobic [Mycobacterium sp. Spyr1]
 gi|315262037|gb|ADT98778.1| coproporphyrinogen III oxidase, anaerobic [Mycobacterium sp. 
Spyr1]
Length=398

 Score =  540 bits (1391),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 272/374 (73%), Positives = 298/374 (80%), Gaps = 3/374 (0%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLG--GVSPDRWLLALRAELELAAAKL-DAPTV  60
            +PFGVY+HVPFC TRCGYCDFNTYTPA+LG  G +PD WL ALRAEL++AAA L + P V
Sbjct  24   RPFGVYIHVPFCATRCGYCDFNTYTPAELGAGGATPDGWLTALRAELQMAAAHLGEPPPV  83

Query  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120
             TV+VGGGTPSLLG   LA +LD VR  F L PDAE++TE+NPEST P FFA +RAAGYT
Sbjct  84   STVFVGGGTPSLLGAAGLARVLDAVRADFTLTPDAEITTESNPESTSPRFFAGLRAAGYT  143

Query  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180
            RVSLGMQS AP VL  LDRVHSPGRA  AA EA AEGF HVNLDLIYGTPGE+DDDL+RS
Sbjct  144  RVSLGMQSTAPHVLRALDRVHSPGRAVDAAREARAEGFDHVNLDLIYGTPGETDDDLLRS  203

Query  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240
             DAAV+AGVDHVS YAL+VE GTALARRVRRGE+A PDDDV A RYEL+D RL+ AGF W
Sbjct  204  ADAAVEAGVDHVSGYALIVEDGTALARRVRRGEIARPDDDVHARRYELLDRRLTDAGFTW  263

Query  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            YEVSNW RP GECRHNLGYWDGGQWWGAGPGAHGY+  TRWWNVKHPN YA  L    LP
Sbjct  264  YEVSNWSRPDGECRHNLGYWDGGQWWGAGPGAHGYVDATRWWNVKHPNAYAATLETGALP  323

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360
            VA  E + A+  H E+V+LK RLR GLP A L A ERERA   +ADGLL   G   VLT 
Sbjct  324  VADLEAIDAETSHVEEVMLKTRLRTGLPAATLSARERERAAVAVADGLLRADGQSFVLTD  383

Query  361  RGRLLADAVVRTLL  374
            RGRLLADAVVR LL
Sbjct  384  RGRLLADAVVRDLL  397


>gi|120404813|ref|YP_954642.1| coproporphyrinogen III oxidase [Mycobacterium vanbaalenii PYR-1]
 gi|119957631|gb|ABM14636.1| coproporphyrinogen III oxidase, anaerobic [Mycobacterium vanbaalenii 
PYR-1]
Length=394

 Score =  539 bits (1389),  Expect = 3e-151, Method: Compositional matrix adjust.
 Identities = 270/375 (72%), Positives = 296/375 (79%), Gaps = 1/375 (0%)

Query  2    PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKL-DAPTV  60
            P QPFG+Y+HVPFC  RCGYCDFNTYTPA+LGG +PD WL ALR EL LAAA L + P V
Sbjct  20   PSQPFGIYVHVPFCAVRCGYCDFNTYTPAELGGANPDGWLSALRTELRLAAAHLGEPPDV  79

Query  61   HTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYT  120
             TV+VGGGTPSLLG   L  +LD +R+ F LAP AEV+TE+NPEST P FF  +R AGYT
Sbjct  80   QTVFVGGGTPSLLGAAGLTAVLDAIREDFTLAPGAEVTTESNPESTSPRFFDGLRRAGYT  139

Query  121  RVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRS  180
            RVSLGMQS AP VLA LDRVHSPGRA  AA EA   GF HVNLDLIYGTPGE+DDDLVRS
Sbjct  140  RVSLGMQSTAPHVLAALDRVHSPGRALDAAREAREAGFDHVNLDLIYGTPGETDDDLVRS  199

Query  181  VDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAW  240
              +AV+AGVDHVSAYAL+VE GTALARRVRRGE+ APDDDVLA RYEL+D RL+ AGF W
Sbjct  200  ASSAVEAGVDHVSAYALIVEDGTALARRVRRGEMPAPDDDVLARRYELLDRRLADAGFDW  259

Query  241  YEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            YEVSNW RPGG+CRHN+GYWDGG+WWGAGPGAHGY+   RWWNVKHPN YA       LP
Sbjct  260  YEVSNWSRPGGQCRHNIGYWDGGEWWGAGPGAHGYVDSVRWWNVKHPNAYAAASDKGELP  319

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTG  360
            VA FE L     H EDV+L+VRLR GLP A L A ER RAE  +ADGLL   GD LVLT 
Sbjct  320  VADFEALDEPTAHIEDVMLRVRLRTGLPAAALSAPERRRAERAVADGLLRTDGDALVLTD  379

Query  361  RGRLLADAVVRTLLG  375
            RGRLLADAVVR LLG
Sbjct  380  RGRLLADAVVRDLLG  394


>gi|118473719|ref|YP_888797.1| coproporphyrinogen III oxidase [Mycobacterium smegmatis str. 
MC2 155]
 gi|118175006|gb|ABK75902.1| putative oxygen-independent coproporphyrinogen III oxidase [Mycobacterium 
smegmatis str. MC2 155]
Length=390

 Score =  531 bits (1367),  Expect = 9e-149, Method: Compositional matrix adjust.
 Identities = 275/373 (74%), Positives = 311/373 (84%), Gaps = 0/373 (0%)

Query  2    PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVH  61
            PG+PFG+Y+HVPFC TRCGYCDFNTYTP++LGG +P+ WL ALR EL LAA ++ A  V 
Sbjct  17   PGRPFGIYIHVPFCATRCGYCDFNTYTPSELGGANPEGWLEALRVELRLAAERVGALAVQ  76

Query  62   TVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTR  121
            TV+VGGGTPSLLGG+ L+ +LD VRD+FVLA  AEV+TEANPEST PE FA +R AGYTR
Sbjct  77   TVFVGGGTPSLLGGDGLSAVLDAVRDNFVLATGAEVTTEANPESTSPELFAALRNAGYTR  136

Query  122  VSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSV  181
            +SLGMQSVAP VLA L+R HSPGRA AA  EA A GF HVNLDLIYGTPGESDDDL+RSV
Sbjct  137  ISLGMQSVAPHVLAVLNRTHSPGRAPAAVAEAKAAGFEHVNLDLIYGTPGESDDDLLRSV  196

Query  182  DAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY  241
            DAAV AGVDHVS YALVVE GTALARRVRRGE+AAPDDDVLAHRYEL+DA+LSAAGFAWY
Sbjct  197  DAAVHAGVDHVSGYALVVEDGTALARRVRRGEIAAPDDDVLAHRYELLDAQLSAAGFAWY  256

Query  242  EVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPV  301
            EVSNW RPGGEC HNLGYWDGG+WWGAGPGAHG++  TRWWN KHPN YA+ LA   LP+
Sbjct  257  EVSNWSRPGGECLHNLGYWDGGEWWGAGPGAHGFLNATRWWNAKHPNAYAQTLAEGALPI  316

Query  302  AGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGR  361
            A FE L A   HTEDV+L++RLR+GL L  L A ER R   ++A+GLLD  G+R+VLT R
Sbjct  317  ADFEVLDAADRHTEDVMLRLRLRRGLALDDLAADERARVPEIVAEGLLDTAGERVVLTDR  376

Query  362  GRLLADAVVRTLL  374
            GRLLAD VVR LL
Sbjct  377  GRLLADGVVRALL  389


>gi|108800439|ref|YP_640636.1| coproporphyrinogen III oxidase [Mycobacterium sp. MCS]
 gi|119869568|ref|YP_939520.1| coproporphyrinogen III oxidase [Mycobacterium sp. KMS]
 gi|108770858|gb|ABG09580.1| coproporphyrinogen III oxidase, anaerobic [Mycobacterium sp. 
MCS]
 gi|119695657|gb|ABL92730.1| coproporphyrinogen III oxidase, anaerobic [Mycobacterium sp. 
KMS]
Length=392

 Score =  500 bits (1287),  Expect = 2e-139, Method: Compositional matrix adjust.
 Identities = 267/373 (72%), Positives = 293/373 (79%), Gaps = 1/373 (0%)

Query  3    GQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPT-VH  61
            G+PFG+Y+HVPFC TRCGYCDFNTYTPA+ GG +P+ WL+A+R EL LAA  L  P  V 
Sbjct  18   GRPFGLYIHVPFCATRCGYCDFNTYTPAEAGGANPEGWLVAMRQELALAARTLGTPPPVR  77

Query  62   TVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTR  121
            TV+VGGGTPSLLGG  L  +L  VR+HF LAP AEV+TEANPES+ PE F  + AAGYTR
Sbjct  78   TVFVGGGTPSLLGGAGLTAVLAAVREHFDLAPGAEVTTEANPESSGPELFDALLAAGYTR  137

Query  122  VSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSV  181
            VSLGMQS A  VL  LDR+HSPGRA AAA EA A GF HVNLDLIYGTPGE+DDDL RS 
Sbjct  138  VSLGMQSTARHVLKVLDRLHSPGRAVAAAGEARAAGFGHVNLDLIYGTPGETDDDLRRSA  197

Query  182  DAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY  241
            DAA+ AGVDHVSAYALVVE GTALARRVRRGE+ APDDDVLA RYEL+DARL  AGF WY
Sbjct  198  DAAIGAGVDHVSAYALVVEDGTALARRVRRGEVTAPDDDVLAARYELLDARLGEAGFDWY  257

Query  242  EVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPV  301
            EVSNW R GGECRHNLGYW GG+WWG GPGAHG++G TRWWNVKHPN YA  L    LPV
Sbjct  258  EVSNWARSGGECRHNLGYWAGGEWWGVGPGAHGFLGDTRWWNVKHPNAYATALGDGALPV  317

Query  302  AGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGR  361
            + FE L   A HTEDV+L+VRLR GLPL  L A ER R   V+ADGL    G  LVLT R
Sbjct  318  SDFEVLDPAARHTEDVMLRVRLRSGLPLDMLTADERSRVGTVVADGLAVVDGAALVLTDR  377

Query  362  GRLLADAVVRTLL  374
            GRLLAD VVRTLL
Sbjct  378  GRLLADGVVRTLL  390


>gi|126436063|ref|YP_001071754.1| coproporphyrinogen III oxidase [Mycobacterium sp. JLS]
 gi|126235863|gb|ABN99263.1| coproporphyrinogen III oxidase, anaerobic [Mycobacterium sp. 
JLS]
Length=392

 Score =  497 bits (1280),  Expect = 1e-138, Method: Compositional matrix adjust.
 Identities = 266/373 (72%), Positives = 293/373 (79%), Gaps = 1/373 (0%)

Query  3    GQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPT-VH  61
            G+PFG+Y+HVPFC TRCGYCDFNTYTPA+ GG +P+ WL+A+R EL LAA  L  P  V 
Sbjct  18   GRPFGLYIHVPFCATRCGYCDFNTYTPAEAGGANPEGWLVAMRQELALAARTLGTPPPVR  77

Query  62   TVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTR  121
            TV+VGGGTPSLLGG  L  +L  VR+HF LAP AEV+TEANPES+ PE F  + AAGYTR
Sbjct  78   TVFVGGGTPSLLGGAGLTAVLAAVREHFELAPGAEVTTEANPESSGPELFDALLAAGYTR  137

Query  122  VSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSV  181
            VSLGMQS A  VL  LDR+HSPGRA AAA EA A GF HVNLDLIYGTPGE+DDDL RS 
Sbjct  138  VSLGMQSTARHVLKVLDRLHSPGRAVAAAGEARAAGFGHVNLDLIYGTPGETDDDLRRSA  197

Query  182  DAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY  241
            DAA+ AGVDHVSAYALVVE GTALARRVRRGE+ APDDDVLA RYEL+DARL  AGF WY
Sbjct  198  DAAIGAGVDHVSAYALVVEDGTALARRVRRGEVTAPDDDVLAARYELLDARLGEAGFDWY  257

Query  242  EVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPV  301
            EVSNW R GGECRHNLGYW GG+WWG GPGAHG++G TRWWNV+HPN YA  L    LPV
Sbjct  258  EVSNWARFGGECRHNLGYWAGGEWWGVGPGAHGFLGDTRWWNVRHPNAYATALGDGALPV  317

Query  302  AGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGR  361
            + FE L   A HTEDV+L+VRLR GLPL  L A ER R   V+ADGL    G  LVLT R
Sbjct  318  SDFEVLDPAARHTEDVMLRVRLRSGLPLDMLTADERSRVGTVVADGLAVVDGAALVLTDR  377

Query  362  GRLLADAVVRTLL  374
            GRLLAD VVRTLL
Sbjct  378  GRLLADGVVRTLL  390


>gi|169628753|ref|YP_001702402.1| coproporphyrinogen III oxidase [Mycobacterium abscessus ATCC 
19977]
 gi|169240720|emb|CAM61748.1| Probable oxygen-independent coproporphyrinogen III oxidase HemN 
[Mycobacterium abscessus]
Length=388

 Score =  485 bits (1248),  Expect = 5e-135, Method: Compositional matrix adjust.
 Identities = 263/376 (70%), Positives = 289/376 (77%), Gaps = 3/376 (0%)

Query  2    PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKLDA-PT  59
            PG+PFG+Y+HVPFC TRCGYCDFNTYT  +LG G SP  WL ALRAELELAA  L   P 
Sbjct  12   PGRPFGIYVHVPFCATRCGYCDFNTYTADELGEGTSPAGWLEALRAELELAARTLAGNPP  71

Query  60   VHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGY  119
            V TV+VGGGTPSLLGG  LA +LD +  HFVLAP AEV+TEANPEST P FF TIRAAGY
Sbjct  72   VETVFVGGGTPSLLGGSGLAEVLDAIGAHFVLAPGAEVTTEANPESTSPAFFDTIRAAGY  131

Query  120  TRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVR  179
            TRVSLGMQS AP VLATLDRVH+PGRA AAA EA A G  HVNLDLIYGTPGE+DDDL R
Sbjct  132  TRVSLGMQSAAPHVLATLDRVHAPGRAVAAAREARAAGLGHVNLDLIYGTPGETDDDLRR  191

Query  180  SVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFA  239
            S+ A ++AGVDHVSAYALVVE GTALARRVRRGEL  PD+D LA RY+L+DA L+ AG  
Sbjct  192  SIAAVLEAGVDHVSAYALVVEEGTALARRVRRGELPNPDEDALADRYQLLDAALTEAGLD  251

Query  240  WYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAG-AT  298
            WYEVSNW RPGG+CRHNLGYW GG WWGAGPGAHG++   RWWNVKHPNTYA  L G   
Sbjct  252  WYEVSNWARPGGQCRHNLGYWAGGDWWGAGPGAHGHVNGVRWWNVKHPNTYARRLLGEGQ  311

Query  299  LPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVL  358
            LPV G E L     HTE+VLL VRL  G+ L  L   ER R  AV+  GL     +RLVL
Sbjct  312  LPVGGHEILSPVERHTEEVLLAVRLNTGIALTDLTIEERGRVPAVVDRGLGRLVDERLVL  371

Query  359  TGRGRLLADAVVRTLL  374
            T +GRLLAD VVR +L
Sbjct  372  TDQGRLLADGVVRAIL  387


>gi|308404907|ref|ZP_07494180.2| HemN C- region superfamily [Mycobacterium tuberculosis SUMu012]
 gi|308365388|gb|EFP54239.1| HemN C- region superfamily [Mycobacterium tuberculosis SUMu012]
Length=245

 Score =  484 bits (1246),  Expect = 9e-135, Method: Compositional matrix adjust.
 Identities = 245/245 (100%), Positives = 245/245 (100%), Gaps = 0/245 (0%)

Query  131  PRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVD  190
            PRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVD
Sbjct  1    PRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVD  60

Query  191  HVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVSNWCRPG  250
            HVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVSNWCRPG
Sbjct  61   HVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVSNWCRPG  120

Query  251  GECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGAD  310
            GECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGAD
Sbjct  121  GECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGAD  180

Query  311  ALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVV  370
            ALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVV
Sbjct  181  ALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVV  240

Query  371  RTLLG  375
            RTLLG
Sbjct  241  RTLLG  245


>gi|226360384|ref|YP_002778162.1| coproporphyrinogen III oxidase [Rhodococcus opacus B4]
 gi|226238869|dbj|BAH49217.1| putative oxygen-independent coproporphyrinogen III oxidase [Rhodococcus 
opacus B4]
Length=402

 Score =  482 bits (1240),  Expect = 5e-134, Method: Compositional matrix adjust.
 Identities = 247/372 (67%), Positives = 283/372 (77%), Gaps = 1/372 (0%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKLDAPTVHT  62
            +PFG+Y+HVPFC TRCGYCDFNTY   +LG   SP  W+  LR EL+LAA    AP V T
Sbjct  30   RPFGIYVHVPFCATRCGYCDFNTYMAGELGTSASPQSWMEGLRRELDLAAQMTGAPAVDT  89

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLGG+ LA +L  VR  F L+  AEV+TE+NPEST PEFF  + A G+TR+
Sbjct  90   VFVGGGTPSLLGGDGLADVLGAVRSSFGLSDGAEVTTESNPESTSPEFFERLLAGGFTRI  149

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQS A  VL  LDR H+PGRA AAA EA A GF HVNLDLIYGTPGE D+DL  S+D
Sbjct  150  SLGMQSAAQHVLKVLDRTHTPGRAVAAALEARAAGFGHVNLDLIYGTPGERDEDLDLSLD  209

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
            A + AGVDHVSAYAL+VE GTALAR+VRRGEL APDDDVLA RYE +DARL+ AG  WYE
Sbjct  210  AVLSAGVDHVSAYALIVEDGTALARKVRRGELPAPDDDVLASRYERIDARLAEAGLTWYE  269

Query  243  VSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVA  302
            VSNW R G  CRHNLGYWDGG WWGAGPGAH ++G  RWWNVKHP  YA+ LA  +LPV 
Sbjct  270  VSNWAREGAACRHNLGYWDGGDWWGAGPGAHSHVGGVRWWNVKHPARYADQLAAGSLPVG  329

Query  303  GFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRG  362
            G EQL  + +H E V+L  RLR GLP+A L   E+  AEAV+ADGLL   G+ LVLT RG
Sbjct  330  GSEQLTGEDVHVERVMLTARLRTGLPVAELDDVEKSAAEAVIADGLLVRAGEHLVLTERG  389

Query  363  RLLADAVVRTLL  374
            RLLADAVVR++L
Sbjct  390  RLLADAVVRSVL  401


>gi|111018259|ref|YP_701231.1| coproporphyrinogen III oxidase [Rhodococcus jostii RHA1]
 gi|110817789|gb|ABG93073.1| probable O2-independent coproporphyrinogen III oxidase [Rhodococcus 
jostii RHA1]
Length=420

 Score =  478 bits (1229),  Expect = 9e-133, Method: Compositional matrix adjust.
 Identities = 250/377 (67%), Positives = 285/377 (76%), Gaps = 6/377 (1%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKLDAPTVHT  62
            +PFG+Y+HVPFC TRCGYCDFNTYT  +LG   SP  W+  LR EL+LAA    AP V T
Sbjct  43   RPFGIYVHVPFCATRCGYCDFNTYTAGELGTSASPQSWMEGLRRELDLAAEMTGAPAVDT  102

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLGG+ L+ +L  VR  F +A  AEV+TE+NPEST PEFF  +RA G+TR+
Sbjct  103  VFVGGGTPSLLGGDGLSDVLGAVRSSFGIAKGAEVTTESNPESTSPEFFERLRAGGFTRI  162

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQS A  VL  LDR H+PGRA AAA EA A GF HVNLDLIYGTPGE D+DL  S+D
Sbjct  163  SLGMQSAAQHVLRVLDRTHTPGRAVAAAQEARAAGFEHVNLDLIYGTPGERDEDLDLSLD  222

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
            A + AGVDHVSAYAL+VE GTALAR+VRRGEL APDDDVLA RYE +DARL+ AG  WYE
Sbjct  223  AVLSAGVDHVSAYALIVEDGTALARKVRRGELPAPDDDVLASRYERIDARLADAGLTWYE  282

Query  243  VSNWCRPG---GE--CRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGA  297
            VSNW       GE  CRHNLGYWD G WWGAGPGAH ++G  RWWNVKHP  YA+ LA  
Sbjct  283  VSNWASADAATGESRCRHNLGYWDDGDWWGAGPGAHSHVGGVRWWNVKHPARYADQLAAG  342

Query  298  TLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLV  357
            +LPV G EQL A+ +H E V+L  RLR GLP+A L AAE+  AE V+ADGLL   G  LV
Sbjct  343  SLPVGGSEQLTAEDVHVERVMLTARLRTGLPVAELDAAEQHAAETVVADGLLVRQGQHLV  402

Query  358  LTGRGRLLADAVVRTLL  374
            LT RGRLLADAVVRT+L
Sbjct  403  LTDRGRLLADAVVRTVL  419


>gi|229493209|ref|ZP_04387001.1| putative oxygen-independent coproporphyrinogen III oxidase [Rhodococcus 
erythropolis SK121]
 gi|229319940|gb|EEN85769.1| putative oxygen-independent coproporphyrinogen III oxidase [Rhodococcus 
erythropolis SK121]
Length=408

 Score =  476 bits (1226),  Expect = 2e-132, Method: Compositional matrix adjust.
 Identities = 244/378 (65%), Positives = 280/378 (75%), Gaps = 7/378 (1%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKLDAPTVHT  62
            +PFG+Y+HVPFC TRCGYCDFNTYT  +LG   SP  WL  LR EL+LAA    AP   T
Sbjct  30   RPFGIYIHVPFCATRCGYCDFNTYTAGELGTSASPQSWLEGLRRELDLAAEMTGAPAAET  89

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLGG+ L  +L  VR  F LAP AEV+TE+NPEST PEFF  +R+AG+TR+
Sbjct  90   VFVGGGTPSLLGGDGLTDVLSAVRSSFGLAPGAEVTTESNPESTSPEFFGALRSAGFTRI  149

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQS A  VL  LDR H+PGRA AAA EA A GF+HVNLDLIYGTPGE D DL  S+D
Sbjct  150  SLGMQSAAQHVLKILDRTHTPGRAVAAAKEARAAGFSHVNLDLIYGTPGERDQDLDASLD  209

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
            A + A VDHVSAYAL+VE GTA+AR+VRRGEL APDDDVLA RYE +D+RLS AG  WYE
Sbjct  210  AVLSADVDHVSAYALIVEDGTAMARKVRRGELPAPDDDVLASRYERIDSRLSEAGLGWYE  269

Query  243  VSNWCRP------GGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAG  296
            VSNW +          CRHN+GYWDGG WWGAGPGAH ++G  RWWNVKHP  YAE LA 
Sbjct  270  VSNWAKAETADSGDTRCRHNIGYWDGGDWWGAGPGAHSHVGGVRWWNVKHPARYAEQLAL  329

Query  297  ATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRL  356
              LPV G E+L A+  H E V+L  RLR GLPL+ L A+ER  AE V+ DGL     D +
Sbjct  330  GELPVGGSEELTAEDEHMERVMLTARLRTGLPLSELSASERLSAEQVVVDGLAVIENDHV  389

Query  357  VLTGRGRLLADAVVRTLL  374
            VLT RGRLLADAV+RT+L
Sbjct  390  VLTDRGRLLADAVIRTIL  407


>gi|226307231|ref|YP_002767191.1| coproporphyrinogen III oxidase [Rhodococcus erythropolis PR4]
 gi|226186348|dbj|BAH34452.1| coproporphyrinogen III oxidase [Rhodococcus erythropolis PR4]
Length=408

 Score =  473 bits (1216),  Expect = 3e-131, Method: Compositional matrix adjust.
 Identities = 244/378 (65%), Positives = 279/378 (74%), Gaps = 7/378 (1%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKLDAPTVHT  62
            +PFG+Y+HVPFC TRCGYCDFNTYT  +LG   SP  WL  LR EL+LAA    AP   T
Sbjct  30   RPFGIYIHVPFCATRCGYCDFNTYTAGELGTSASPQSWLEGLRRELDLAAEMTGAPAAKT  89

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLGG+ L+ +L  VR  F LA  AEV+TE+NPEST PEFF  +R+AG+TR+
Sbjct  90   VFVGGGTPSLLGGDGLSDVLSAVRSSFGLASGAEVTTESNPESTSPEFFDALRSAGFTRI  149

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQS A  VL  LDR H+PGRA AAA EA A GF+HVNLDLIYGTPGE D DL  S+D
Sbjct  150  SLGMQSAAQHVLKILDRTHTPGRAVAAAKEARAAGFSHVNLDLIYGTPGERDQDLDASLD  209

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
            A + A VDHVSAYAL+VE GTA+AR+VRRGEL APDDDVLA RYE +D+RLS AG  WYE
Sbjct  210  AVLSADVDHVSAYALIVEDGTAMARKVRRGELPAPDDDVLASRYERIDSRLSEAGLHWYE  269

Query  243  VSNWCRP------GGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAG  296
            VSNW +          CRHNLGYWDGG WWGAGPGAH ++G  RWWNVKHP  YAE LA 
Sbjct  270  VSNWAKAETADSGDTRCRHNLGYWDGGDWWGAGPGAHSHVGGVRWWNVKHPARYAEQLAL  329

Query  297  ATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRL  356
              LPV G E L A+  H E V+L  RLR GLPL+ L A+ER  AE V+ DGL     D +
Sbjct  330  GELPVGGSEDLTAEDEHMERVMLTARLRTGLPLSELSASERLSAEQVVVDGLAVIENDHV  389

Query  357  VLTGRGRLLADAVVRTLL  374
            VLT RGRLLADAV+RT+L
Sbjct  390  VLTDRGRLLADAVIRTIL  407


>gi|325677129|ref|ZP_08156798.1| coproporphyrinogen dehydrogenase [Rhodococcus equi ATCC 33707]
 gi|325552114|gb|EGD21807.1| coproporphyrinogen dehydrogenase [Rhodococcus equi ATCC 33707]
Length=395

 Score =  464 bits (1193),  Expect = 1e-128, Method: Compositional matrix adjust.
 Identities = 247/373 (67%), Positives = 279/373 (75%), Gaps = 2/373 (0%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKLDAPTVHT  62
            +PFG+Y+HVPFC TRCGYCDFNTYT  +LG   SP  WL AL+ EL  AA    AP V T
Sbjct  22   RPFGIYVHVPFCATRCGYCDFNTYTAGELGTSASPQSWLEALKRELASAAEITGAPKVDT  81

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLGG+ LA +L  V+  F LA  AEV+TE+NPEST PEFF  +R AG+TR+
Sbjct  82   VFVGGGTPSLLGGDGLAEVLGAVQASFGLADGAEVTTESNPESTSPEFFTRLREAGFTRI  141

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQS A  VL  LDR H+PGRA AAA EA A GF HVNLDLIYGTPGE+D DL  S+D
Sbjct  142  SLGMQSAAEHVLRVLDRTHTPGRAVAAAREARAAGFDHVNLDLIYGTPGETDRDLDASLD  201

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
            A + AGVDHVSAYAL+VE GTALAR+VRRGEL APDDDVLA RYE +DARL+ AG  WYE
Sbjct  202  AVLGAGVDHVSAYALIVEDGTALARKVRRGELPAPDDDVLASRYERIDARLADAGLHWYE  261

Query  243  VSNW-CRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPV  301
            VSNW       CRHNLGYWDGG WWGAGPGAH ++G  RWWNVKHP  YA+ L+   LPV
Sbjct  262  VSNWAANDASRCRHNLGYWDGGDWWGAGPGAHSHVGGVRWWNVKHPARYADRLSAGELPV  321

Query  302  AGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGR  361
             G E L A+  H E V+L VRLR GLPL+ LG +ER  AE V+ADGL    G  LVLT R
Sbjct  322  GGSETLTAEDAHVERVMLTVRLRTGLPLSDLGDSERGAAERVVADGLARVEGAHLVLTDR  381

Query  362  GRLLADAVVRTLL  374
            GRLLADAVVR +L
Sbjct  382  GRLLADAVVRDIL  394


>gi|312140297|ref|YP_004007633.1| oxygen-independent coproporphyrinogen-iii oxidase hemn [Rhodococcus 
equi 103S]
 gi|311889636|emb|CBH48953.1| oxygen-independent coproporphyrinogen-III oxidase HemN [Rhodococcus 
equi 103S]
Length=395

 Score =  461 bits (1186),  Expect = 9e-128, Method: Compositional matrix adjust.
 Identities = 247/373 (67%), Positives = 278/373 (75%), Gaps = 2/373 (0%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKLDAPTVHT  62
            +PFG+Y+HVPFC TRCGYCDFNTYT  +LG   SP  WL AL+ EL  AA    AP V T
Sbjct  22   RPFGIYVHVPFCATRCGYCDFNTYTAGELGTSASPQSWLEALKRELASAAEITGAPKVDT  81

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLGG+ LA +L  V+  F LA  AEV+TE+NPEST PEFF  +R AG+TR+
Sbjct  82   VFVGGGTPSLLGGDGLAEVLGAVQASFGLADGAEVTTESNPESTSPEFFTRLREAGFTRI  141

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQS A  VL  LDR H+PGRA AAA EA A GF HVNLDLIYGTPGE+D DL  S+D
Sbjct  142  SLGMQSAAEHVLRVLDRTHTPGRAVAAAREARAAGFDHVNLDLIYGTPGETDRDLDASLD  201

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
            A + AGVDHVSAYAL+VE GTALAR+VRRGEL APDDDVLA RYE +DARL+ AG  WYE
Sbjct  202  AVLGAGVDHVSAYALIVEDGTALARKVRRGELPAPDDDVLASRYERIDARLADAGLHWYE  261

Query  243  VSNW-CRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPV  301
            VSNW       CRHNLGYWDGG WWGAGPGAH ++G  RWWNVKHP  YA+ L    LPV
Sbjct  262  VSNWAANDASRCRHNLGYWDGGDWWGAGPGAHSHVGGVRWWNVKHPARYADRLWAGELPV  321

Query  302  AGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGR  361
             G E L A+  H E V+L VRLR GLPL+ LG +ER  AE V+ADGL    G  LVLT R
Sbjct  322  GGSETLTAEDAHVERVMLTVRLRTGLPLSDLGDSERGAAERVVADGLARVEGAHLVLTDR  381

Query  362  GRLLADAVVRTLL  374
            GRLLADAVVR +L
Sbjct  382  GRLLADAVVRDIL  394


>gi|326381607|ref|ZP_08203301.1| coproporphyrinogen III oxidase [Gordonia neofelifaecis NRRL B-59395]
 gi|326199854|gb|EGD57034.1| coproporphyrinogen III oxidase [Gordonia neofelifaecis NRRL B-59395]
Length=407

 Score =  452 bits (1162),  Expect = 6e-125, Method: Compositional matrix adjust.
 Identities = 230/381 (61%), Positives = 269/381 (71%), Gaps = 10/381 (2%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVS-PDRWLLALRAELELAAAKL-DAPTVH  61
            +P  +YLHVPFC TRCGYCDFNTYT  +LG  S P  W+  +RAEL+ AAA L     V 
Sbjct  25   RPLSLYLHVPFCATRCGYCDFNTYTAGELGSSSSPQSWMEGVRAELDQAAALLARGREVS  84

Query  62   TVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTR  121
            TV+VGGGTPSLLGG+ LA LLD VRD F LAP AEV+TE+NPEST PEFF  +R AG+TR
Sbjct  85   TVFVGGGTPSLLGGQGLARLLDAVRDSFDLAPGAEVTTESNPESTSPEFFGALRDAGFTR  144

Query  122  VSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSV  181
            +SLGMQS AP VLA L+R H+PGRA  AA EA A GF HVNLD+IYGTPGE D DL  ++
Sbjct  145  ISLGMQSAAPHVLAVLERTHTPGRALDAAREASAAGFEHVNLDMIYGTPGERDTDLRETL  204

Query  182  DAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY  241
            DA +   VDHVSAYAL+VE GT  AR+VRRGE+  PDDDVLA RYE++DARLS AG  WY
Sbjct  205  DAVLSVPVDHVSAYALIVEDGTRFARKVRRGEVPMPDDDVLAARYEMIDARLSEAGMTWY  264

Query  242  EVSNWCR--------PGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEI  293
            EVSNW R        P   CRHN  YW    WWG GPGAH ++   RWWN KHP TY+  
Sbjct  265  EVSNWARAQADSLPAPQSVCRHNEAYWRSDDWWGVGPGAHSHVNGVRWWNQKHPATYSAS  324

Query  294  LAGATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHG  353
            LA   LP+ G E L    +HTE V+L++R+R GLP   L + ER+RA+A +A GLL   G
Sbjct  325  LADGALPIGGQEILSEADIHTESVMLRLRMRDGLPANLLDSGERQRADAAVARGLLTVAG  384

Query  354  DRLVLTGRGRLLADAVVRTLL  374
            +  VLT  GRLLAD VVR +L
Sbjct  385  EAYVLTDAGRLLADGVVRDML  405


>gi|333918863|ref|YP_004492444.1| Coproporphyrinogen dehydrogenase [Amycolicicoccus subflavus DQS3-9A1]
 gi|333481084|gb|AEF39644.1| Coproporphyrinogen dehydrogenase [Amycolicicoccus subflavus DQS3-9A1]
Length=399

 Score =  451 bits (1160),  Expect = 8e-125, Method: Compositional matrix adjust.
 Identities = 232/379 (62%), Positives = 274/379 (73%), Gaps = 5/379 (1%)

Query  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGG-VSPDRWLLALRAELELAAAKLDA--  57
            +P + FG+Y+HVPFC TRCGYCDFNTYT  +LG   SP+ WL A + E ELAA  L A  
Sbjct  18   VPERRFGIYVHVPFCATRCGYCDFNTYTAGELGSSASPESWLEAFKRETELAAKMLSAAG  77

Query  58   -PTVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRA  116
             P   +V+VGGGTPSLLG   LA ++D + + F + P+AEV+TEANPEST P+FF TIR 
Sbjct  78   VPQADSVFVGGGTPSLLGAAALADVIDTISNTFGIRPNAEVTTEANPESTSPQFFQTIRE  137

Query  117  AGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDD  176
            AG+TRVSLGMQS A  VLA LDR H+PGRA +AA EA   GF HVNLDLIYGTPGE D D
Sbjct  138  AGFTRVSLGMQSAAQHVLAALDRTHTPGRAISAAQEAREAGFKHVNLDLIYGTPGERDSD  197

Query  177  LVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAA  236
            L  S+DA + AG DHVSAYAL+VE GTALARR+R+GE+ APDDDVLA RYEL+D+RL+ A
Sbjct  198  LDASLDAVLAAGADHVSAYALIVEDGTALARRIRKGEMPAPDDDVLAARYELIDSRLAGA  257

Query  237  GFAWYEVSNW-CRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILA  295
            GF WYEVSNW       CRHN+GYW+   WWG GPGAH ++G  RWWN KHP  YA+ LA
Sbjct  258  GFQWYEVSNWAANEEAICRHNVGYWNESNWWGIGPGAHSHVGGVRWWNAKHPARYADQLA  317

Query  296  GATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDR  355
               LPV G E L A+  H E V+L VR+R GL L RL +AER  AE    +GL +    R
Sbjct  318  SGFLPVGGVETLSAEDQHLEYVMLAVRMRAGLALRRLSSAERAAAERCADEGLAEIAEGR  377

Query  356  LVLTGRGRLLADAVVRTLL  374
            L LTGRGRLLAD VVR ++
Sbjct  378  LRLTGRGRLLADGVVRQIV  396


>gi|324998261|ref|ZP_08119373.1| coproporphyrinogen III oxidase, anaerobic [Pseudonocardia sp. 
P1]
Length=395

 Score =  451 bits (1160),  Expect = 9e-125, Method: Compositional matrix adjust.
 Identities = 237/375 (64%), Positives = 273/375 (73%), Gaps = 5/375 (1%)

Query  5    PFGVYLHVPFCLTRCGYCDFNTYTPAQLGG--VSPDRWLLALRAELELAAAKLDAPTVHT  62
            PFG+Y+HVPFC TRCGYCDFNTYT ++L G   SP+ WL A R E+ LAA  +   TV T
Sbjct  12   PFGIYVHVPFCATRCGYCDFNTYTASELAGDASSPEGWLEAARREIALAARTVGDRTVET  71

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPSLLG +RL+ ++  +R  F +AP  EV+TE+NPEST PEFFA IR  GYTRV
Sbjct  72   VFVGGGTPSLLGADRLSAVMAAIRSEFRVAPGCEVTTESNPESTSPEFFAGIRDGGYTRV  131

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQS A  VLA LDR H+PGRA  AA EA A GF HVNLDLIY TPGE+DDDL RS D
Sbjct  132  SLGMQSAARHVLAVLDRTHTPGRAVDAAREARAAGFGHVNLDLIYATPGETDDDLRRSAD  191

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
            A ++AGVDHVSAYAL+VE GTALARRVRRGEL APDDDV A RYEL+DARL  AG  WYE
Sbjct  192  AVLEAGVDHVSAYALIVEDGTALARRVRRGELPAPDDDVAATRYELLDARLRDAGLRWYE  251

Query  243  VSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVA  302
            VSNW  PG ECRHNLGYW  G WWG GPGAH ++  TRWWNVKHP  +A +LA   +P A
Sbjct  252  VSNWSLPGAECRHNLGYWRDGDWWGVGPGAHSHLAGTRWWNVKHPARWAGLLADGAVPEA  311

Query  303  GFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLD---YHGDRLVLT  359
            G E+L     HTE V+L++RL +G+PL  L    R  A     +GLL+   +   R VLT
Sbjct  312  GREELTPAERHTESVMLRLRLAEGMPLGLLDDGGRAAASRAAGEGLLEPAAHDAGRAVLT  371

Query  360  GRGRLLADAVVRTLL  374
             RGRLLAD VV  LL
Sbjct  372  DRGRLLADRVVTDLL  386


>gi|296140464|ref|YP_003647707.1| oxygen-independent coproporphyrinogen III oxidase [Tsukamurella 
paurometabola DSM 20162]
 gi|296028598|gb|ADG79368.1| oxygen-independent coproporphyrinogen III oxidase [Tsukamurella 
paurometabola DSM 20162]
Length=391

 Score =  450 bits (1158),  Expect = 2e-124, Method: Compositional matrix adjust.
 Identities = 240/372 (65%), Positives = 271/372 (73%), Gaps = 2/372 (0%)

Query  5    PFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVS-PDRWLLALRAELELAAAKLDAPTVHTV  63
            PFG+YLHVPFC TRCGYCDFNTYT  +LGG S P  W  A+  EL LA A +    VHTV
Sbjct  19   PFGLYLHVPFCATRCGYCDFNTYTAGELGGSSSPQAWAEAIDGELALARATVGDVPVHTV  78

Query  64   YVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVS  123
            +VGGGTPSLLGG+ LA LLD  R HF    +AE++TE+NPEST PEFF  +R AG+TRVS
Sbjct  79   FVGGGTPSLLGGDGLAALLDTARRHFRFVDNAEITTESNPESTSPEFFRRLRDAGFTRVS  138

Query  124  LGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDA  183
            LGMQS A  VL  LDR H+PGRA AAA EA A GF HVNLDLIYGTPGE+D DL  S+DA
Sbjct  139  LGMQSAAAHVLTVLDRTHTPGRAVAAAKEARAAGFEHVNLDLIYGTPGETDADLAASLDA  198

Query  184  AVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEV  243
             + AGVDHVSAYAL+VE GTALARR+RRGEL   DDDVLA RYE VD  L  AGF WYEV
Sbjct  199  VLDAGVDHVSAYALIVEDGTALARRIRRGELPDTDDDVLARRYEQVDGALRGAGFDWYEV  258

Query  244  SNWCRP-GGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVA  302
            SNW R     C HN  YW+G  WWGAGPGAHG+I  TR WN+KHP  YA+ +    LP+A
Sbjct  259  SNWARSDAARCHHNELYWEGANWWGAGPGAHGHIAGTRVWNIKHPARYADAVGRGELPLA  318

Query  303  GFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRG  362
            G E L A+  H EDV+L+VR+R GLPLA L  AERERA+A  A+G LD  G   VLT  G
Sbjct  319  GHETLTAEQQHVEDVMLRVRMRSGLPLAVLRPAERERADAEAAEGNLDRVGAAYVLTDAG  378

Query  363  RLLADAVVRTLL  374
            RLLAD VVR +L
Sbjct  379  RLLADGVVRRIL  390


>gi|343926586|ref|ZP_08766088.1| oxygen-independent coproporphyrinogen III oxidase [Gordonia alkanivorans 
NBRC 16433]
 gi|343763507|dbj|GAA13014.1| oxygen-independent coproporphyrinogen III oxidase [Gordonia alkanivorans 
NBRC 16433]
Length=403

 Score =  447 bits (1150),  Expect = 1e-123, Method: Compositional matrix adjust.
 Identities = 239/377 (64%), Positives = 274/377 (73%), Gaps = 5/377 (1%)

Query  2    PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVS-PDRWLLALRAELELAAAKLDAPT-  59
            P  PFG+YLHVPFC TRCGYCDFNTYT  +LG  S P+ W  A+ AELE +AA+L APT 
Sbjct  26   PDVPFGLYLHVPFCATRCGYCDFNTYTAGELGSTSSPESWQEAVAAELE-SAARLLAPTR  84

Query  60   -VHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAG  118
             V T++VGGGTPSLLG + L  LLD VR +F LAPDAEV+TE+NPEST P FF  +R AG
Sbjct  85   KVSTIFVGGGTPSLLGADGLTRLLDAVRANFDLAPDAEVTTESNPESTSPAFFEQLRGAG  144

Query  119  YTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLV  178
            +TR+SLGMQS A  VL  LDRVH+PGRA AAA EA A GF HVNLDLIYGTPGE+D DL 
Sbjct  145  FTRISLGMQSAAQHVLKVLDRVHTPGRAVAAAREARAAGFDHVNLDLIYGTPGETDADLH  204

Query  179  RSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGF  238
             ++DA + AGVDHVSAYAL+VE GTALARR+RRGE+ APDDDVLA RY+++D RL A GF
Sbjct  205  TTLDAVLSAGVDHVSAYALIVEDGTALARRIRRGEMPAPDDDVLADRYKILDDRLGANGF  264

Query  239  AWYEVSNWC-RPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGA  297
             WYEVSNW     G CRHNL YW+   WWG GPGAH ++   RWWNVKHP  YA+ L   
Sbjct  265  GWYEVSNWALDDAGACRHNLAYWNSSDWWGIGPGAHSHVNGVRWWNVKHPARYAQTLKEG  324

Query  298  TLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLV  357
             LP A  EQL A+  H E V+L  RLR GLP   L  AER  AE + ADGLL   G   V
Sbjct  325  VLPAASSEQLTAEDRHMEAVMLTTRLRTGLPNDLLDDAERANAEKLCADGLLGSTGGAYV  384

Query  358  LTGRGRLLADAVVRTLL  374
            LT  GRLLAD V+R +L
Sbjct  385  LTDAGRLLADGVIRRVL  401


>gi|302528865|ref|ZP_07281207.1| coproporphyrinogen III oxidase [Streptomyces sp. AA4]
 gi|302437760|gb|EFL09576.1| coproporphyrinogen III oxidase [Streptomyces sp. AA4]
Length=423

 Score =  447 bits (1149),  Expect = 2e-123, Method: Compositional matrix adjust.
 Identities = 242/380 (64%), Positives = 272/380 (72%), Gaps = 9/380 (2%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGV-SPDRWLLALRAELELAAAKL-DAPTVH  61
            +PFGVY+HVPFC TRCGYCDFNTYT  +LG   SP  WL ALR ELEL A  L  AP   
Sbjct  45   RPFGVYVHVPFCATRCGYCDFNTYTAGELGSAASPRSWLDALRRELELGAEILGSAPPAE  104

Query  62   TVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTR  121
            TV+VGGGTPSLLG + LA +LD VR  F LAP AEV+TE+NPEST PEFFA IR AGYTR
Sbjct  105  TVFVGGGTPSLLGADGLAEVLDGVRSAFGLAPGAEVTTESNPESTSPEFFAGIRDAGYTR  164

Query  122  VSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSV  181
            VSLGMQS A  VL  LDRVH+PGR   AA EA A GF HVNLDLIYGTPGE  +DL  S+
Sbjct  165  VSLGMQSAARHVLKVLDRVHTPGRPVDAAREARAAGFEHVNLDLIYGTPGERVEDLRASL  224

Query  182  DAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY  241
            DA + AGVDHVSAYAL+VE GTALARRVRRGEL APDDD LA  YEL+D+ L++AG  WY
Sbjct  225  DAVLSAGVDHVSAYALIVEDGTALARRVRRGELPAPDDDTLASYYELIDSVLASAGLTWY  284

Query  242  EVSNWCR-PGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            EVSNW       CRHNLGYW GG WWGAGPGAH ++G  RWWNVKHP  Y+ +LA    P
Sbjct  285  EVSNWVSDEAARCRHNLGYWQGGDWWGAGPGAHSHVGGVRWWNVKHPAKYSSLLAEGQSP  344

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGL-----LDYHGDR  355
             A  E L  +  H E ++L++R+  GL L+ L  A  + A A  A+GL     LD  G R
Sbjct  345  EADREVLTPEDRHLERIMLELRISDGLALSALDEAGLKEARAAAAEGLLEQSDLDSQG-R  403

Query  356  LVLTGRGRLLADAVVRTLLG  375
             VLT RGRLLADAVVR L G
Sbjct  404  AVLTDRGRLLADAVVRRLAG  423


>gi|257055326|ref|YP_003133158.1| coproporphyrinogen III oxidase, anaerobic [Saccharomonospora 
viridis DSM 43017]
 gi|256585198|gb|ACU96331.1| coproporphyrinogen III oxidase, anaerobic [Saccharomonospora 
viridis DSM 43017]
Length=422

 Score =  445 bits (1144),  Expect = 6e-123, Method: Compositional matrix adjust.
 Identities = 240/377 (64%), Positives = 272/377 (73%), Gaps = 6/377 (1%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKL-DAPTVH  61
            +PFGVY+HVPFC TRCGYCDFNTYT  +LG   SP  W   LR EL+LA   L D P   
Sbjct  45   RPFGVYVHVPFCATRCGYCDFNTYTAGELGTAASPASWFDGLRRELDLAVTTLGDPPPAD  104

Query  62   TVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTR  121
            TV+VGGGTPSLLG + LA +LD VRD F LA D EV+TE+NPEST PEFFA +R AGYTR
Sbjct  105  TVFVGGGTPSLLGADGLARVLDAVRDTFGLASDVEVTTESNPESTSPEFFAGLREAGYTR  164

Query  122  VSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSV  181
            VSLGMQS AP VL  LDRVH+PGR   AA EA A GF HVNLDLIYGTPGE   DL  SV
Sbjct  165  VSLGMQSTAPHVLRVLDRVHTPGRPTQAAAEARAAGFEHVNLDLIYGTPGERTADLRASV  224

Query  182  DAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY  241
            +A ++AGVDHVSAYAL+VE GTALARRVR+GE+ APDDDVLA  YEL+D+ L+ AG  WY
Sbjct  225  EAVLEAGVDHVSAYALIVEEGTALARRVRKGEIPAPDDDVLAADYELIDSMLTDAGLRWY  284

Query  242  EVSNW-CRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            EVSNW   P   CRHNLGYW GG WWGAGPGAH ++G  RWWNVKHP  YA +LA   LP
Sbjct  285  EVSNWAASPDARCRHNLGYWRGGDWWGAGPGAHSHVGGVRWWNVKHPARYAAVLADGKLP  344

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHG---DRLV  357
            VAG E+L     + E V+L++RL +GLPL  L       A+  + DGLLD         V
Sbjct  345  VAGQEELTDSERYLERVMLELRLAEGLPLDVLDDDGLREAKRAVEDGLLDRDAAARGHAV  404

Query  358  LTGRGRLLADAVVRTLL  374
            LT RGRLLADAVVR L+
Sbjct  405  LTDRGRLLADAVVRRLV  421


>gi|54023388|ref|YP_117630.1| coproporphyrinogen III oxidase [Nocardia farcinica IFM 10152]
 gi|54014896|dbj|BAD56266.1| putative oxygen-independent coproporphyrinogen III oxidase [Nocardia 
farcinica IFM 10152]
Length=424

 Score =  439 bits (1130),  Expect = 3e-121, Method: Compositional matrix adjust.
 Identities = 246/379 (65%), Positives = 278/379 (74%), Gaps = 7/379 (1%)

Query  3    GQPFGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKL-----D  56
            G PFG+Y+HVPFC TRCGYCDFNTYT  +LG   SP  WL ALR EL  AAA+       
Sbjct  45   GGPFGIYVHVPFCATRCGYCDFNTYTAGELGTSASPQSWLAALRGELATAAAQFARLPSP  104

Query  57   APTVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRA  116
             P V TV+VGGGTPSLLGGE LA +LD VR +F +A DAE++TE+NPEST P FF  +R 
Sbjct  105  VPPVATVFVGGGTPSLLGGEGLAEVLDAVRANFTVAADAEITTESNPESTSPRFFERLRE  164

Query  117  AGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDD  176
            AGYTR+SLGMQS A  VLA LDR H+PGRA AAA EA A GF HVNLDLIYGTPGE+D D
Sbjct  165  AGYTRISLGMQSAAQHVLAVLDRTHTPGRAVAAAREARAAGFEHVNLDLIYGTPGETDAD  224

Query  177  LVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAA  236
            L  ++DA + AGVDHVSAY+L+VE GTALARRVRRGEL APD+DVLA RYE +D RL+AA
Sbjct  225  LDATLDAVLAAGVDHVSAYSLIVEDGTALARRVRRGELPAPDEDVLAARYERIDRRLTAA  284

Query  237  GFAWYEVSNW-CRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILA  295
            G AWYEVSNW       CRHNLGYWDGG W GAGPGAH ++G  RWWNVKHP  YAE +A
Sbjct  285  GLAWYEVSNWAATESARCRHNLGYWDGGDWLGAGPGAHSHLGGVRWWNVKHPARYAERVA  344

Query  296  GATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDR  355
               LP AG+E L  D  + E V+L VRLR GLPLA L  A     + V+ADGL       
Sbjct  345  RGGLPAAGWEALTDDERYLERVMLTVRLRTGLPLADLAPAAAPALDRVVADGLATRTPTH  404

Query  356  LVLTGRGRLLADAVVRTLL  374
            LVLT RGRLLADAVVR L+
Sbjct  405  LVLTDRGRLLADAVVRRLV  423


>gi|317508577|ref|ZP_07966238.1| HemN protein [Segniliparus rugosus ATCC BAA-974]
 gi|316253121|gb|EFV12530.1| HemN protein [Segniliparus rugosus ATCC BAA-974]
Length=399

 Score =  437 bits (1125),  Expect = 1e-120, Method: Compositional matrix adjust.
 Identities = 228/379 (61%), Positives = 266/379 (71%), Gaps = 6/379 (1%)

Query  2    PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVS-PDRWLLALRAELELAAAKLD----  56
            P  PFGVY+HVPFC +RCGYCDFNTYTP +LGG S    WL AL  EL+LAA+ L     
Sbjct  19   PDAPFGVYVHVPFCASRCGYCDFNTYTPGELGGRSGTGEWLTALGQELDLAASALGRAGG  78

Query  57   APTVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRA  116
             PTV TV+VGGGTPSLLG   LA +LD +   F +A   E + EANPEST P FF  IRA
Sbjct  79   PPTVRTVFVGGGTPSLLGAAGLARVLDAIGARFPMAESLEATCEANPESTSPAFFEGIRA  138

Query  117  AGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDD  176
            AGYTRVSLGMQS A  VLA LDR H+PGRA  AA EA A G  HVNLDLIYGTPGE++ D
Sbjct  139  AGYTRVSLGMQSEAAHVLAVLDRAHTPGRATRAAQEARASGIEHVNLDLIYGTPGETEPD  198

Query  177  LVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAA  236
            L RS+ A VQA VDHVSAYAL V  GTA+ R V +GELAAPDDDVLA R+ +VD  L+AA
Sbjct  199  LARSLAAVVQAPVDHVSAYALTVHQGTAMGRAVAKGELAAPDDDVLAERHAMVDEALAAA  258

Query  237  GFAWYEVSNWCR-PGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILA  295
            GF WYEVSNW + P   CRHNLGYW GG WWGAGPGAH ++   RWWN KHP  +A + A
Sbjct  259  GFEWYEVSNWAKSPEARCRHNLGYWQGGDWWGAGPGAHSHVNGVRWWNAKHPARHAALAA  318

Query  296  GATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDR  355
                PVAGFE L  +  HTEDV+L++R+R+G+  A L   E +RA  ++A+GLL    DR
Sbjct  319  SGRAPVAGFEALTDEERHTEDVMLRLRVREGVARAVLRGPELDRAAQLVAEGLLLEQTDR  378

Query  356  LVLTGRGRLLADAVVRTLL  374
            + L    R+LAD +   LL
Sbjct  379  IALAPSSRMLADGLAVRLL  397


>gi|62391133|ref|YP_226535.1| coproporphyrinogen III oxidase [Corynebacterium glutamicum ATCC 
13032]
 gi|161486712|ref|NP_601492.2| coproporphyrinogen III oxidase [Corynebacterium glutamicum ATCC 
13032]
 gi|41326472|emb|CAF20634.1| PUTATIVE ANAEROBIC COPROPORPHYRINOGEN III OXIDASE [Corynebacterium 
glutamicum ATCC 13032]
Length=380

 Score =  436 bits (1120),  Expect = 4e-120, Method: Compositional matrix adjust.
 Identities = 212/372 (57%), Positives = 272/372 (74%), Gaps = 3/372 (0%)

Query  6    FGVYLHVPFCLTRCGYCDFNTYTPAQLGGVS-PDRWLLALRAELELAAAKLDAP-TVHTV  63
            FGVY+HVPFC TRCGYCDFNTYT  +LG  + PD +L +L  ELE+A A LD P    T+
Sbjct  4    FGVYIHVPFCSTRCGYCDFNTYTAGELGSTAGPDTYLDSLEVELEMAVASLDNPRQAETI  63

Query  64   YVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVS  123
            ++GGGTPSL+G + LA +L  VR+ F +A  AEV+TE+NPEST PEFF  +R AGY R+S
Sbjct  64   FIGGGTPSLIGADGLARVLGAVRNTFGIADGAEVTTESNPESTSPEFFDGLREAGYNRIS  123

Query  124  LGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDA  183
            LGMQS +  VL  LDR H+PGR  AAA EA   GF HVNLD+IYGTP E+DDD+ +++DA
Sbjct  124  LGMQSASSSVLKVLDRTHTPGRPVAAAKEAREAGFEHVNLDMIYGTPTETDDDVRKTLDA  183

Query  184  AVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEV  243
             ++A VDHVSAY+L+VE GTA+AR+VR+GEL APD+DV A R+EL+DARL +AGF WYEV
Sbjct  184  VLEANVDHVSAYSLIVEDGTAMARKVRKGELPAPDEDVYADRFELIDARLRSAGFDWYEV  243

Query  244  SNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAG  303
            SNW +PGGEC+HN+GYW  G WWGAGPGAH +IG  R++N+KHP  Y+  +A   LP+  
Sbjct  244  SNWAKPGGECKHNMGYWVDGDWWGAGPGAHSHIGDRRFYNIKHPARYSAQIAAGELPIKE  303

Query  304  FEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHG-DRLVLTGRG  362
             E+L A+  HTE V+L +RL+QG+PL     A R   +  +A GLL  +    L +T  G
Sbjct  304  TERLTAEDHHTERVMLGLRLKQGVPLNLFAPAARPVIDRHIAGGLLHVNALGNLAVTDAG  363

Query  363  RLLADAVVRTLL  374
            RLLAD ++  +L
Sbjct  364  RLLADGIIADIL  375


>gi|300788491|ref|YP_003768782.1| oxygen-independent coproporphyrinogen III oxidase [Amycolatopsis 
mediterranei U32]
 gi|299798005|gb|ADJ48380.1| oxygen-independent coproporphyrinogen III oxidase [Amycolatopsis 
mediterranei U32]
 gi|340530096|gb|AEK45301.1| oxygen-independent coproporphyrinogen III oxidase [Amycolatopsis 
mediterranei S699]
Length=410

 Score =  435 bits (1118),  Expect = 6e-120, Method: Compositional matrix adjust.
 Identities = 242/378 (65%), Positives = 271/378 (72%), Gaps = 9/378 (2%)

Query  6    FGVYLHVPFCLTRCGYCDFNTYTPAQL-GGVSPDRWLLALRAELELAAAKLDAP-TVHTV  63
            FGVY+HVPFC TRCGYCDFNTYT  +L  G SP+ WL  LR ELELAA  L  P    TV
Sbjct  34   FGVYVHVPFCATRCGYCDFNTYTAGELDSGSSPESWLEGLRRELELAARTLVVPPAADTV  93

Query  64   YVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVS  123
            +VGGGTPSLLG + L ++LD VRD F LAP AEV+TE+NPEST PEFFA IR AGYTR+S
Sbjct  94   FVGGGTPSLLGADGLRSVLDAVRDVFGLAPGAEVTTESNPESTSPEFFAGIREAGYTRIS  153

Query  124  LGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDA  183
            LGMQS AP VL  LDRVH+PGR   AA EA A GF HVNLD+IYGTPGE  DDL  ++DA
Sbjct  154  LGMQSAAPHVLKILDRVHTPGRPGKAAAEARAAGFEHVNLDVIYGTPGERADDLRATLDA  213

Query  184  AVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEV  243
             + AGVDHVSAYAL+VE GTALARRVRRGEL APDDDVLA  YE++DA LS+AG  WYEV
Sbjct  214  VLAAGVDHVSAYALIVEEGTALARRVRRGELPAPDDDVLAADYEMIDAMLSSAGLRWYEV  273

Query  244  SNW-CRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVA  302
            SNW       CRHNLGYW G  WWGAGPGAH ++G  RWWNVKHP  YA +LAG   P A
Sbjct  274  SNWAASDAARCRHNLGYWRGDDWWGAGPGAHSHVGGVRWWNVKHPARYAALLAGGDSPAA  333

Query  303  GFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLAD-----GLLDYHGDRLV  357
            G E L  D  H E ++L++R+ +GLPL  L A     A A  A+       LD  G R V
Sbjct  334  GREVLTDDDQHLERIMLELRVAEGLPLDVLDAPGLAEARAAAAEGLLDPSALDSRG-RAV  392

Query  358  LTGRGRLLADAVVRTLLG  375
            LT RGRLLAD VVR L G
Sbjct  393  LTDRGRLLADGVVRRLAG  410


>gi|344044709|gb|EGV40385.1| coproporphyrinogen III oxidase [Corynebacterium glutamicum S9114]
Length=380

 Score =  435 bits (1118),  Expect = 7e-120, Method: Compositional matrix adjust.
 Identities = 212/372 (57%), Positives = 271/372 (73%), Gaps = 3/372 (0%)

Query  6    FGVYLHVPFCLTRCGYCDFNTYTPAQLGGVS-PDRWLLALRAELELAAAKLDAP-TVHTV  63
            FGVY+HVPFC TRCGYCDFNTYT  +LG  + PD +L +L  ELE+A A LD P    T+
Sbjct  4    FGVYIHVPFCSTRCGYCDFNTYTAGELGSTAGPDTYLDSLEVELEMAVASLDNPRQAETI  63

Query  64   YVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVS  123
            ++GGGTPSL+G + LA +L  VR+ F +A  AEV+TE+NPEST PEFF  +R AGY R+S
Sbjct  64   FIGGGTPSLIGADGLARVLGAVRNTFGIADGAEVTTESNPESTSPEFFDGLREAGYNRIS  123

Query  124  LGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDA  183
            LGMQS +  VL  LDR H+PGR  AAA EA   GF HVNLD+IYGTP E+DDD+ +++DA
Sbjct  124  LGMQSASSSVLKVLDRTHTPGRPVAAAKEARRAGFEHVNLDMIYGTPTETDDDVRKTLDA  183

Query  184  AVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEV  243
             ++A VDHVSAY+L+VE GTA+AR+VR+GEL APD+DV A R+EL+DARL +AGF WYEV
Sbjct  184  VLEANVDHVSAYSLIVEDGTAMARKVRKGELPAPDEDVYADRFELIDARLRSAGFDWYEV  243

Query  244  SNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAG  303
            SNW +PGGEC+HN+GYW  G WWGAGPGAH +IG  R++N+KHP  Y+  +A   LP+  
Sbjct  244  SNWAKPGGECKHNMGYWVDGDWWGAGPGAHSHIGDRRFYNIKHPARYSAQIAAGELPIKE  303

Query  304  FEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHG-DRLVLTGRG  362
             E L A+  HTE V+L +RL+QG+PL     A R   +  +A GLL  +    L +T  G
Sbjct  304  TEMLTAEDHHTERVMLGLRLKQGVPLNLFAPAARPVIDRHIAGGLLHINALGNLAVTDAG  363

Query  363  RLLADAVVRTLL  374
            RLLAD ++  +L
Sbjct  364  RLLADGIIADIL  375


>gi|262203055|ref|YP_003274263.1| oxygen-independent coproporphyrinogen III oxidase [Gordonia bronchialis 
DSM 43247]
 gi|262086402|gb|ACY22370.1| oxygen-independent coproporphyrinogen III oxidase [Gordonia bronchialis 
DSM 43247]
Length=401

 Score =  432 bits (1112),  Expect = 4e-119, Method: Compositional matrix adjust.
 Identities = 237/376 (64%), Positives = 271/376 (73%), Gaps = 3/376 (0%)

Query  2    PGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVS-PDRWLLALRAELELAAAKLD-APT  59
            P  PFG+YLHVPFC TRCGYCDFNTYT  +LG  S P+ W  A+ AELELAA  L  A  
Sbjct  24   PDTPFGLYLHVPFCATRCGYCDFNTYTAGELGSSSSPESWRRAVAAELELAAGMLSPARP  83

Query  60   VHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGY  119
            V +++VGGGTPSLLG   L  LLD VRD+F LA DAE++TE+NPEST P FF  + AAG+
Sbjct  84   VSSIFVGGGTPSLLGASGLTELLDRVRDNFELADDAEITTESNPESTSPAFFDGLAAAGF  143

Query  120  TRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVR  179
            TRVSLGMQS AP VLA LDR+H+PGRA AAA EA A GF HVNLDLIYGTPGE+D DL  
Sbjct  144  TRVSLGMQSAAPHVLAVLDRIHTPGRAVAAAREATAAGFDHVNLDLIYGTPGETDADLHA  203

Query  180  SVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFA  239
            S+DA + AGVDHVSAYAL+VE GTALARR+RRGE+ APDDDVLA RY ++D RL+ AGF+
Sbjct  204  SIDAVLDAGVDHVSAYALIVEDGTALARRIRRGEMPAPDDDVLADRYRILDRRLTDAGFS  263

Query  240  WYEVSNWCRP-GGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGAT  298
            WYEVSNW R   GECRHNL YW    WWG GPGAH ++   RWWNVKHP  YA+ L    
Sbjct  264  WYEVSNWARSASGECRHNLAYWRSDDWWGIGPGAHSHVNGVRWWNVKHPARYAQTLGERH  323

Query  299  LPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVL  358
            LP A  E L  +  H E V+L  R R+GLP + L  AE  RA  +  DGLL    D  VL
Sbjct  324  LPRASSETLTPEDRHVETVMLTARCREGLPASALDDAENRRARELCGDGLLTAGEDSYVL  383

Query  359  TGRGRLLADAVVRTLL  374
            T  GRLLAD VVR +L
Sbjct  384  TDEGRLLADGVVRRIL  399


>gi|227833636|ref|YP_002835343.1| oxygen-independent coproporphyrinogen III oxidase [Corynebacterium 
aurimucosum ATCC 700975]
 gi|227454652|gb|ACP33405.1| oxygen-independent coproporphyrinogen III oxidase [Corynebacterium 
aurimucosum ATCC 700975]
Length=382

 Score =  429 bits (1103),  Expect = 4e-118, Method: Compositional matrix adjust.
 Identities = 209/370 (57%), Positives = 268/370 (73%), Gaps = 1/370 (0%)

Query  5    PFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVY  64
            PFG+Y+HVPFC +RCGYCDFNTYTP +LGG     +L+AL  ELE+AA ++D     TV+
Sbjct  3    PFGLYIHVPFCASRCGYCDFNTYTPGELGGDLTSDYLVALEKELEMAAVQVDR-EAETVF  61

Query  65   VGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSL  124
            +GGGTPSLLG E L  +L  VRD F LAP AEV+TE+NPEST PE+FA +  AG+TR+SL
Sbjct  62   IGGGTPSLLGAEGLGRVLSKVRDTFGLAPGAEVTTESNPESTSPEYFAGLLDAGFTRLSL  121

Query  125  GMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAA  184
            GMQS +P VLA L+R H+PGRA  AA EAIA GF HVNLD+IYGTP E D D+  +++ A
Sbjct  122  GMQSASPGVLAVLERAHTPGRAFDAAREAIAAGFEHVNLDMIYGTPTEEDADVALTLERA  181

Query  185  VQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVS  244
            ++ GVDH+SAY+L+VE GT +AR+V +G L APD+DVLA RYE++ + L A GF WYEVS
Sbjct  182  LETGVDHISAYSLIVEDGTRMARKVSKGLLPAPDEDVLARRYEMISSTLEAEGFEWYEVS  241

Query  245  NWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGF  304
            NW +PGGEC+HN  YW  G WWGAGPGAH ++G  R++NVK+P TY + +    LP+   
Sbjct  242  NWAKPGGECQHNRIYWVDGNWWGAGPGAHSHLGNERFYNVKNPRTYIKAVGEGELPIKER  301

Query  305  EQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRL  364
            EQL     HTE ++L +RLR+G+P + L  A    A   +  GLL+  GDRL +T  GRL
Sbjct  302  EQLTEADRHTERIMLGLRLREGMPASWLAPAAEPVAARSIERGLLERAGDRLRVTKAGRL  361

Query  365  LADAVVRTLL  374
            LAD ++  LL
Sbjct  362  LADGIITDLL  371


>gi|256375378|ref|YP_003099038.1| coproporphyrinogen III oxidase [Actinosynnema mirum DSM 43827]
 gi|255919681|gb|ACU35192.1| oxygen-independent coproporphyrinogen III oxidase [Actinosynnema 
mirum DSM 43827]
Length=404

 Score =  425 bits (1093),  Expect = 6e-117, Method: Compositional matrix adjust.
 Identities = 238/376 (64%), Positives = 267/376 (72%), Gaps = 6/376 (1%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKLDAP-TVH  61
            +PFGVY+HVPFC TRCGYCDFNTYT  +LG   SP+ WL  LR EL+LAA  L +P    
Sbjct  28   RPFGVYVHVPFCATRCGYCDFNTYTAGELGTSASPESWLEGLRRELDLAARVLGSPPAAE  87

Query  62   TVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTR  121
            TV+VGGGTPSLLG + LA +L+ VR    LAP AEV+TE+NPEST  EFFA IR AGYTR
Sbjct  88   TVFVGGGTPSLLGADGLAAVLEAVRSSVGLAPGAEVTTESNPESTSSEFFAAIREAGYTR  147

Query  122  VSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSV  181
            VSLGMQS A  VL  LDR H+PGRAAAAA EA   GF HVNLDLIYGTPGE D+DL  S+
Sbjct  148  VSLGMQSAARHVLQILDRKHTPGRAAAAAREAREGGFEHVNLDLIYGTPGERDEDLRESL  207

Query  182  DAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWY  241
                 AGVDH+SAYAL+VE GTALARRVRRGEL APDDDVLA RYE+VDA     G +WY
Sbjct  208  AVVRDAGVDHLSAYALIVEEGTALARRVRRGELPAPDDDVLAERYEMVDAAAREMGMSWY  267

Query  242  EVSNW-CRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLP  300
            EVSNW     G CRHN+ YW G  WWGAGPGAH ++G  RWWNVKHP  YA +LAG   P
Sbjct  268  EVSNWAASEEGRCRHNVLYWQGADWWGAGPGAHSHVGGVRWWNVKHPAKYAAVLAGGGSP  327

Query  301  VAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHG---DRLV  357
             AG E L  D    E VLL++RL +GLP+  L    R  A  V A+GLL+       R V
Sbjct  328  AAGREVLAEDDRRVERVLLELRLSEGLPVEVLDRDGRREAARVAAEGLLEPMALARGRCV  387

Query  358  LTGRGRLLADAVVRTL  373
            LT RGRLLADAVVR L
Sbjct  388  LTDRGRLLADAVVRRL  403


>gi|25028747|ref|NP_738801.1| coproporphyrinogen III oxidase [Corynebacterium efficiens YS-314]
 gi|23494033|dbj|BAC19001.1| putative oxygen-independent coproporphyrinogen III oxidase [Corynebacterium 
efficiens YS-314]
Length=401

 Score =  421 bits (1082),  Expect = 1e-115, Method: Compositional matrix adjust.
 Identities = 214/386 (56%), Positives = 272/386 (71%), Gaps = 12/386 (3%)

Query  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVS-PDRWLLALRAELELAAAKL----  55
            +P   FGVY+HVPFC TRCGYCDFNTYT  +LG  + PD +L AL  ELE+A A+L    
Sbjct  6    VPRSVFGVYVHVPFCSTRCGYCDFNTYTAGELGSTAGPDTYLDALEVELEMAVARLAAAH  65

Query  56   ----DAP---TVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWP  108
                D P      TV++GGGTPSL+G + L+ +L  +R+ F LAP AE++TE+NPEST P
Sbjct  66   EADSDQPGPRPAETVFIGGGTPSLIGADGLSRVLSGIRNTFGLAPGAEITTESNPESTSP  125

Query  109  EFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYG  168
            EFF  +R +GY R+SLGMQS +  VL  LDR H+PGR  AAA EA A GF HVNLD+IYG
Sbjct  126  EFFDALRESGYNRISLGMQSASSSVLRVLDRRHTPGRPVAAAKEARAAGFDHVNLDMIYG  185

Query  169  TPGESDDDLVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYEL  228
            TP E+D+D+ +++DA ++A VDHVSAY+L+VE GTA+AR+VRRGEL APD+DV A RYE+
Sbjct  186  TPTETDEDVRKTLDAVLEADVDHVSAYSLIVEDGTAMARKVRRGELPAPDEDVYADRYEM  245

Query  229  VDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPN  288
            +D RL A GF WYEVSNW +PGGECRHN+GYW  G WWGAGPGAH +IG  R++NVKHP 
Sbjct  246  IDQRLRANGFDWYEVSNWAKPGGECRHNMGYWVDGDWWGAGPGAHSHIGDHRFYNVKHPA  305

Query  289  TYAEILAGATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGL  348
             Y+  +AG  LP+   E L AD  HTE V+L +RL+QGLP      +     +  +  GL
Sbjct  306  RYSAQIAGGELPIMDTELLTADDHHTERVMLGLRLKQGLPAGIFSPSAHRVIDRHIDRGL  365

Query  349  LDYHGDRLVLTGRGRLLADAVVRTLL  374
            L   G  + +T  GRLLAD ++  +L
Sbjct  366  LHRVGGNIAVTDAGRLLADGIIADIL  391


>gi|259507808|ref|ZP_05750708.1| oxygen-independent coproporphyrinogen III oxidase [Corynebacterium 
efficiens YS-314]
 gi|259164601|gb|EEW49155.1| oxygen-independent coproporphyrinogen III oxidase [Corynebacterium 
efficiens YS-314]
Length=398

 Score =  421 bits (1082),  Expect = 1e-115, Method: Compositional matrix adjust.
 Identities = 214/386 (56%), Positives = 272/386 (71%), Gaps = 12/386 (3%)

Query  1    MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVS-PDRWLLALRAELELAAAKL----  55
            +P   FGVY+HVPFC TRCGYCDFNTYT  +LG  + PD +L AL  ELE+A A+L    
Sbjct  3    VPRSVFGVYVHVPFCSTRCGYCDFNTYTAGELGSTAGPDTYLDALEVELEMAVARLAAAH  62

Query  56   ----DAP---TVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWP  108
                D P      TV++GGGTPSL+G + L+ +L  +R+ F LAP AE++TE+NPEST P
Sbjct  63   EADSDQPGPRPAETVFIGGGTPSLIGADGLSRVLSGIRNTFGLAPGAEITTESNPESTSP  122

Query  109  EFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYG  168
            EFF  +R +GY R+SLGMQS +  VL  LDR H+PGR  AAA EA A GF HVNLD+IYG
Sbjct  123  EFFDALRESGYNRISLGMQSASSSVLRVLDRRHTPGRPVAAAKEARAAGFDHVNLDMIYG  182

Query  169  TPGESDDDLVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYEL  228
            TP E+D+D+ +++DA ++A VDHVSAY+L+VE GTA+AR+VRRGEL APD+DV A RYE+
Sbjct  183  TPTETDEDVRKTLDAVLEADVDHVSAYSLIVEDGTAMARKVRRGELPAPDEDVYADRYEM  242

Query  229  VDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPN  288
            +D RL A GF WYEVSNW +PGGECRHN+GYW  G WWGAGPGAH +IG  R++NVKHP 
Sbjct  243  IDQRLRANGFDWYEVSNWAKPGGECRHNMGYWVDGDWWGAGPGAHSHIGDHRFYNVKHPA  302

Query  289  TYAEILAGATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGL  348
             Y+  +AG  LP+   E L AD  HTE V+L +RL+QGLP      +     +  +  GL
Sbjct  303  RYSAQIAGGELPIMDTELLTADDHHTERVMLGLRLKQGLPAGIFSPSAHRVIDRHIDRGL  362

Query  349  LDYHGDRLVLTGRGRLLADAVVRTLL  374
            L   G  + +T  GRLLAD ++  +L
Sbjct  363  LHRVGGNIAVTDAGRLLADGIIADIL  388


>gi|134098063|ref|YP_001103724.1| coproporphyrinogen III oxidase [Saccharopolyspora erythraea NRRL 
2338]
 gi|133910686|emb|CAM00799.1| putative oxygen-independent coproporphyrinogen III oxidase [Saccharopolyspora 
erythraea NRRL 2338]
Length=409

 Score =  420 bits (1079),  Expect = 2e-115, Method: Compositional matrix adjust.
 Identities = 232/381 (61%), Positives = 268/381 (71%), Gaps = 10/381 (2%)

Query  4    QPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSP-DRWLLALRAELELAAAKLDA-----  57
            +PFGVY+HVPFC TRCGYCDFNTYT  +LG  +    WL  LRAEL+L A  L A     
Sbjct  28   RPFGVYVHVPFCATRCGYCDFNTYTADELGSSAGFGSWLEGLRAELDLGARVLAAGGEPV  87

Query  58   PTVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAA  117
            P   TV+ GGGTPSLLG ERL  +LD VR  F LA  AEV+TE+NPEST PEFF  I AA
Sbjct  88   PAAGTVFAGGGTPSLLGAERLGEVLDAVRSSFGLADGAEVTTESNPESTSPEFFEGIAAA  147

Query  118  GYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDL  177
            GYTRVSLGMQS A  VL  L+R H+PGRA  AA EA A GF HVNLDLIYGTPGE+DDDL
Sbjct  148  GYTRVSLGMQSAAQHVLRVLERRHTPGRAVEAAREARAAGFGHVNLDLIYGTPGETDDDL  207

Query  178  VRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAG  237
              S+DA ++AGVDHVSAY+L+VE GTA+AR+VRRG+L  PD+DVLA RYEL+D  L  AG
Sbjct  208  RASLDAVLEAGVDHVSAYSLIVEDGTAMARKVRRGDLPMPDEDVLADRYELLDGVLGGAG  267

Query  238  FAWYEVSNWCR-PGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAG  296
              WYEVSNW R     C HN+GYW GG WWGAGPGAH ++G  RWWNVKHP  Y+ +LA 
Sbjct  268  LHWYEVSNWARDDAARCMHNIGYWRGGDWWGAGPGAHSHVGGVRWWNVKHPARYSALLAE  327

Query  297  ATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLD---YHG  353
               P    E L A+    E V+L++RL  GLPLA L  A R  A+  +ADGLL       
Sbjct  328  GASPALAREVLDAEDQRIERVMLELRLASGLPLAVLDEAGRLAAKEAVADGLLRADALAA  387

Query  354  DRLVLTGRGRLLADAVVRTLL  374
            DR VLT RGRLLAD V++ L+
Sbjct  388  DRCVLTDRGRLLADGVIQRLI  408


>gi|38234293|ref|NP_940060.1| coproporphyrinogen III oxidase [Corynebacterium diphtheriae NCTC 
13129]
 gi|38200556|emb|CAE50251.1| Putative oxygen-independent coproporphyrinogen III oxidase [Corynebacterium 
diphtheriae]
Length=377

 Score =  419 bits (1078),  Expect = 3e-115, Method: Compositional matrix adjust.
 Identities = 205/370 (56%), Positives = 262/370 (71%), Gaps = 1/370 (0%)

Query  6    FGVYLHVPFCLTRCGYCDFNTYTPAQLGGV-SPDRWLLALRAELELAAAKLDAPTVHTVY  64
            FGVY+HVPFC +RCGYCDFNTYTP +LGG  SP+ +L AL  ELELAAA        TV+
Sbjct  5    FGVYVHVPFCSSRCGYCDFNTYTPGELGGTASPESYLDALEKELELAAASGTTRPATTVF  64

Query  65   VGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSL  124
            +GGGTPS+LG   L  +L  VR+   +AP AEV+TE+NPE+T PEFF+ +  AGY R+SL
Sbjct  65   IGGGTPSMLGASGLTRVLSAVRNTIGIAPGAEVTTESNPETTSPEFFSELLDAGYNRISL  124

Query  125  GMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAA  184
            GMQS +  VL  L+R H+PGRA  AA EA+  GF HVNLD+IYGTP E+DDD+  +++ A
Sbjct  125  GMQSASSSVLRVLERKHTPGRAFDAALEAMNAGFLHVNLDMIYGTPTETDDDVRLTLERA  184

Query  185  VQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVS  244
            +  GVDH+SAY+L+VE GTA+AR+V +G+L  P++DV A RY L+D  L A GF WYEVS
Sbjct  185  LDTGVDHISAYSLIVEDGTAMARKVHKGQLPPPNEDVYADRYGLIDTALRAQGFDWYEVS  244

Query  245  NWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGF  304
            NW +PGGEC+HNLGYW  G WWGAGPGAH +I   R++NVKHP+TYA+ LA   LP+   
Sbjct  245  NWAKPGGECQHNLGYWLDGDWWGAGPGAHSHIASRRFFNVKHPSTYAQHLADGQLPIKEE  304

Query  305  EQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRL  364
            E L +   H E V+L +RLRQGL L+R   AER   E  +   LL  +  R+  T +GRL
Sbjct  305  ELLDSTERHEESVMLGLRLRQGLELSRFTEAERAVIEKYVGLKLLHIYDGRVASTLQGRL  364

Query  365  LADAVVRTLL  374
            L D ++  +L
Sbjct  365  LIDGIIADIL  374


>gi|213965780|ref|ZP_03393972.1| putative oxygen-independent coproporphyrinogen III oxidase [Corynebacterium 
amycolatum SK46]
 gi|213951539|gb|EEB62929.1| putative oxygen-independent coproporphyrinogen III oxidase [Corynebacterium 
amycolatum SK46]
Length=387

 Score =  419 bits (1077),  Expect = 3e-115, Method: Compositional matrix adjust.
 Identities = 220/376 (59%), Positives = 269/376 (72%), Gaps = 7/376 (1%)

Query  6    FGVYLHVPFCLTRCGYCDFNTYTPAQLG-GVSPDRWLLALRAELELAAAKLD--APTVHT  62
            FGVYLHVPFC TRCGYCDFNTYTP QLG G +   +L A+ AELE+A  K    A    T
Sbjct  11   FGVYLHVPFCATRCGYCDFNTYTPGQLGSGATQGDYLDAIVAELEMAVVKHPELARGADT  70

Query  63   VYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRV  122
            V+VGGGTPS+LG   L  LLD VR+ F LA DAEV+TE+NPEST PEFF  +  AG+TRV
Sbjct  71   VFVGGGTPSMLGASGLRRLLDGVRNSFGLADDAEVTTESNPESTSPEFFEGLAEAGFTRV  130

Query  123  SLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVD  182
            SLGMQS  P VL TLDR H+PGR AAA  EA A GF H+NLD+IYGTPGES  DL  +++
Sbjct  131  SLGMQSAVPHVLTTLDRTHTPGRPAAAVAEARAAGFEHINLDVIYGTPGESMADLDTTLE  190

Query  183  AAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYE  242
            A +   VDHVSAY+L+VE GTA+AR+VRRGEL  PDDD LA RYE +DA LS AGF+WYE
Sbjct  191  AVLATEVDHVSAYSLIVEPGTAMARKVRRGELPMPDDDDLADRYERIDAALSQAGFSWYE  250

Query  243  VSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVA  302
            VSNW +PGG+CRHN+ YW  G WWGAGPGAH ++  TR++N KHP  YA  ++G  LP+ 
Sbjct  251  VSNWAKPGGQCRHNMIYWRDGNWWGAGPGAHSHLDGTRFYNAKHPARYAATISGGELPIK  310

Query  303  GFEQLGADALHTEDVLLKVRLRQGLPLARLGAAE----RERAEAVLADGLLDYHGDRLVL  358
              E+L A+  HTE ++L +RL +G+    LG  E    R +AEA + + +    G R+ L
Sbjct  311  DSEELTAEDRHTEKIMLGLRLAEGIDANLLGEDELGKARRQAEAGMVEFVSVDGGQRIQL  370

Query  359  TGRGRLLADAVVRTLL  374
            T RGRLLADA++  +L
Sbjct  371  TNRGRLLADAIIVDIL  386



Lambda     K      H
   0.321    0.138    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 718963958700


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40