BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2407

Length=273
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609544|ref|NP_216923.1|  ribonuclease Z [Mycobacterium tuber...   544    4e-153
gi|31793586|ref|NP_856079.1|  ribonuclease Z [Mycobacterium bovis...   518    3e-145
gi|289575101|ref|ZP_06455328.1|  ribonuclease Z [Mycobacterium tu...   517    9e-145
gi|121638288|ref|YP_978512.1|  ribonuclease Z [Mycobacterium bovi...   516    2e-144
gi|340627418|ref|YP_004745870.1|  hypothetical protein MCAN_24411...   515    3e-144
gi|240169957|ref|ZP_04748616.1|  ribonuclease Z [Mycobacterium ka...   444    7e-123
gi|183983707|ref|YP_001851998.1|  metal-dependent hydrolase [Myco...   441    6e-122
gi|161350067|ref|NP_336961.2|  ribonuclease Z [Mycobacterium tube...   441    7e-122
gi|118618938|ref|YP_907270.1|  ribonuclease Z [Mycobacterium ulce...   440    1e-121
gi|13882195|gb|AAK46775.1|  arylsulfatase, putative [Mycobacteriu...   430    9e-119
gi|254818757|ref|ZP_05223758.1|  ribonuclease Z [Mycobacterium in...   416    2e-114
gi|342857805|ref|ZP_08714461.1|  ribonuclease Z [Mycobacterium co...   408    4e-112
gi|41408318|ref|NP_961154.1|  ribonuclease Z [Mycobacterium avium...   404    6e-111
gi|333990144|ref|YP_004522758.1|  metal-dependent hydrolase [Myco...   401    5e-110
gi|296170536|ref|ZP_06852120.1|  ribonuclease Z [Mycobacterium pa...   399    2e-109
gi|120404862|ref|YP_954691.1|  ribonuclease Z [Mycobacterium vanb...   395    3e-108
gi|145223256|ref|YP_001133934.1|  ribonuclease Z [Mycobacterium g...   392    3e-107
gi|118468499|ref|YP_888836.1|  ribonuclease Z [Mycobacterium smeg...   390    1e-106
gi|118466889|ref|YP_880999.1|  ribonuclease Z [Mycobacterium aviu...   380    9e-104
gi|108800472|ref|YP_640669.1|  ribonuclease Z [Mycobacterium sp. ...   362    3e-98 
gi|41017532|sp|Q49744.2|RNZ_MYCLE  RecName: Full=Putative ribonuc...   194    1e-47 
gi|466962|gb|AAA17148.1|  B1937_C1_163 [Mycobacterium leprae]          182    6e-44 
gi|197105711|ref|YP_002131088.1|  metallo-beta-lactamase family p...   157    2e-36 
gi|220916746|ref|YP_002492050.1|  Ribonuclease Z [Anaeromyxobacte...   148    8e-34 
gi|167646632|ref|YP_001684295.1|  ribonuclease Z [Caulobacter sp....   148    1e-33 
gi|163792586|ref|ZP_02186563.1|  ribonuclease Z [alpha proteobact...   147    1e-33 
gi|197121970|ref|YP_002133921.1|  ribonuclease Z [Anaeromyxobacte...   146    3e-33 
gi|149927436|ref|ZP_01915691.1|  ribonuclease Z [Limnobacter sp. ...   145    7e-33 
gi|85708124|ref|ZP_01039190.1|  metallo-beta-lactamase family pro...   143    3e-32 
gi|254514783|ref|ZP_05126844.1|  ribonuclease Z [gamma proteobact...   142    4e-32 
gi|340788141|ref|YP_004753606.1|  hydrolase [Collimonas fungivora...   139    4e-31 
gi|154251904|ref|YP_001412728.1|  ribonuclease Z [Parvibaculum la...   136    3e-30 
gi|254490530|ref|ZP_05103716.1|  metallo-beta-lactamase superfami...   135    6e-30 
gi|241663940|ref|YP_002982300.1|  beta-lactamase domain-containin...   134    1e-29 
gi|16125428|ref|NP_419992.1|  ribonuclease Z [Caulobacter crescen...   134    1e-29 
gi|221234171|ref|YP_002516607.1|  ribonuclease Z [Caulobacter cre...   134    2e-29 
gi|187929827|ref|YP_001900314.1|  beta-lactamase domain-containin...   133    2e-29 
gi|309781470|ref|ZP_07676206.1|  hydrolase [Ralstonia sp. 5_7_47F...   133    2e-29 
gi|114799524|ref|YP_760010.1|  ribonuclease Z [Hyphomonas neptuni...   130    2e-28 
gi|119474698|ref|ZP_01615051.1|  ribonuclease Z [marine gamma pro...   129    4e-28 
gi|299065910|emb|CBJ37090.1|  putative arylsulfatase (Aryl-sulfat...   128    1e-27 
gi|334195076|gb|AEG68261.1|  arylsulfatase precursor (aryl-sulfat...   127    1e-27 
gi|117618007|ref|YP_855738.1|  ribonuclease Z, putative [Aeromona...   127    2e-27 
gi|206590350|emb|CAQ37311.1|  arylsulfatase precursor (aryl-sulfa...   127    2e-27 
gi|83749087|ref|ZP_00946093.1|  Metal-dependent hydrolase [Ralsto...   127    2e-27 
gi|300703243|ref|YP_003744845.1|  arylsulfatase [Ralstonia solana...   127    2e-27 
gi|17547214|ref|NP_520616.1|  hydrolase [Ralstonia solanacearum G...   125    5e-27 
gi|300690635|ref|YP_003751630.1|  arylsulfatase (aryl-sulfate sul...   125    6e-27 
gi|344167403|emb|CCA79626.1|  putative arylsulfatase (Aryl-sulfat...   125    6e-27 
gi|330830709|ref|YP_004393661.1|  ribonuclease Z [Aeromonas veron...   125    9e-27 


>gi|15609544|ref|NP_216923.1| ribonuclease Z [Mycobacterium tuberculosis H37Rv]
 gi|148662240|ref|YP_001283763.1| ribonuclease Z [Mycobacterium tuberculosis H37Ra]
 gi|167966868|ref|ZP_02549145.1| ribonuclease Z [Mycobacterium tuberculosis H37Ra]
 12 more sequence titles
 Length=273

 Score =  544 bits (1402),  Expect = 4e-153, Method: Compositional matrix adjust.
 Identities = 273/273 (100%), Positives = 273/273 (100%), Gaps = 0/273 (0%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT
Sbjct  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60

Query  61   HLHGDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPP  120
            HLHGDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPP
Sbjct  61   HLHGDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPP  120

Query  121  IEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPCDSLDQLA  180
            IEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPCDSLDQLA
Sbjct  121  IEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPCDSLDQLA  180

Query  181  AGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTHYVPAIGP  240
            AGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTHYVPAIGP
Sbjct  181  AGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTHYVPAIGP  240

Query  241  GQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  273
            GQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR
Sbjct  241  GQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  273


>gi|31793586|ref|NP_856079.1| ribonuclease Z [Mycobacterium bovis AF2122/97]
 gi|148823610|ref|YP_001288364.1| ribonuclease Z [Mycobacterium tuberculosis F11]
 gi|253798515|ref|YP_003031516.1| hypothetical protein TBMG_01567 [Mycobacterium tuberculosis KZN 
1435]
 54 more sequence titles
 Length=280

 Score =  518 bits (1335),  Expect = 3e-145, Method: Compositional matrix adjust.
 Identities = 273/280 (98%), Positives = 273/280 (98%), Gaps = 7/280 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT
Sbjct  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA
Sbjct  61   HLHSDHIAELGDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC
Sbjct  121  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
            DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH
Sbjct  181  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  273
            YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR
Sbjct  241  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  280


>gi|289575101|ref|ZP_06455328.1| ribonuclease Z [Mycobacterium tuberculosis K85]
 gi|339632434|ref|YP_004724076.1| hypothetical protein MAF_24220 [Mycobacterium africanum GM041182]
 gi|289539532|gb|EFD44110.1| ribonuclease Z [Mycobacterium tuberculosis K85]
 gi|339331790|emb|CCC27492.1| conserved hypothetical protein [Mycobacterium africanum GM041182]
Length=280

 Score =  517 bits (1331),  Expect = 9e-145, Method: Compositional matrix adjust.
 Identities = 272/280 (98%), Positives = 272/280 (98%), Gaps = 7/280 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT
Sbjct  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA
Sbjct  61   HLHSDHIAELGDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPV PTIGFRIESDGASVVLAGDTVPC
Sbjct  121  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVKPTIGFRIESDGASVVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
            DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH
Sbjct  181  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  273
            YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR
Sbjct  241  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  280


>gi|121638288|ref|YP_978512.1| ribonuclease Z [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224990782|ref|YP_002645469.1| ribonuclease Z [Mycobacterium bovis BCG str. Tokyo 172]
 gi|166991488|sp|A1KL99.1|RNZ_MYCBP RecName: Full=Ribonuclease Z; Short=RNase Z; AltName: Full=tRNA 
3 endonuclease; AltName: Full=tRNase Z
 gi|254808649|sp|C1AQX2.1|RNZ_MYCBT RecName: Full=Ribonuclease Z; Short=RNase Z; AltName: Full=tRNA 
3 endonuclease; AltName: Full=tRNase Z
 gi|121493936|emb|CAL72411.1| Conserved hypothetical protein [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|224773895|dbj|BAH26701.1| ribonuclease Z [Mycobacterium bovis BCG str. Tokyo 172]
 gi|341602326|emb|CCC65000.1| conserved hypothetical protein [Mycobacterium bovis BCG str. 
Moreau RDJ]
Length=280

 Score =  516 bits (1329),  Expect = 2e-144, Method: Compositional matrix adjust.
 Identities = 272/280 (98%), Positives = 273/280 (98%), Gaps = 7/280 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT
Sbjct  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA
Sbjct  61   HLHSDHIAELGDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC
Sbjct  121  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
            DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSV+EAAATANRAGVGTLVMTH
Sbjct  181  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVREAAATANRAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  273
            YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR
Sbjct  241  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  280


>gi|340627418|ref|YP_004745870.1| hypothetical protein MCAN_24411 [Mycobacterium canettii CIPT 
140010059]
 gi|340005608|emb|CCC44772.1| conserved hypothetical protein [Mycobacterium canettii CIPT 140010059]
Length=280

 Score =  515 bits (1326),  Expect = 3e-144, Method: Compositional matrix adjust.
 Identities = 271/280 (97%), Positives = 271/280 (97%), Gaps = 7/280 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT
Sbjct  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLITSWVTNFA DPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA
Sbjct  61   HLHSDHIAELGDVLITSWVTNFATDPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC
Sbjct  121  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
            DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANR GVGTLVMTH
Sbjct  181  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRVGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  273
            YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR
Sbjct  241  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  280


>gi|240169957|ref|ZP_04748616.1| ribonuclease Z [Mycobacterium kansasii ATCC 12478]
Length=280

 Score =  444 bits (1142),  Expect = 7e-123, Method: Compositional matrix adjust.
 Identities = 232/280 (83%), Positives = 250/280 (90%), Gaps = 7/280 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+EITLLGTGSPIPDP+RAGP+TLVRA  Q FL+DCGRGVLQRAAAVGVGAAGLSA+L+T
Sbjct  1    MIEITLLGTGSPIPDPNRAGPATLVRADGQVFLIDCGRGVLQRAAAVGVGAAGLSALLIT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDV+IT+WVTNFA    PL IIGPPGTAEVV ATL+AFGHDIGYRIAHHA
Sbjct  61   HLHSDHIAELGDVIITNWVTNFAPAAPPLQIIGPPGTAEVVAATLRAFGHDIGYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DL  PPP+EVHEYT G  WDR+GVTIRVAPTDHRPV PTIGFRIES G SVVLAGDTVPC
Sbjct  121  DLDAPPPVEVHEYTEGTVWDREGVTIRVAPTDHRPVAPTIGFRIESGGVSVVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
             SLD+LAAGADALVHTVIRKDI+  +PQQRVKD+CDYHSSVQEAAATANRAGVGTLVMTH
Sbjct  181  ASLDELAAGADALVHTVIRKDILAHVPQQRVKDVCDYHSSVQEAAATANRAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  273
            YVPAI  GQE+QWRALAATEFSG IE+G+DLHRVEVHPRR
Sbjct  241  YVPAIIAGQEDQWRALAATEFSGTIELGDDLHRVEVHPRR  280


>gi|183983707|ref|YP_001851998.1| metal-dependent hydrolase [Mycobacterium marinum M]
 gi|254808650|sp|B2HMC3.1|RNZ_MYCMM RecName: Full=Ribonuclease Z; Short=RNase Z; AltName: Full=tRNA 
3 endonuclease; AltName: Full=tRNase Z
 gi|183177033|gb|ACC42143.1| metal-dependent hydrolase [Mycobacterium marinum M]
Length=279

 Score =  441 bits (1134),  Expect = 6e-122, Method: Compositional matrix adjust.
 Identities = 240/279 (87%), Positives = 248/279 (89%), Gaps = 7/279 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+EITLLGTGSPIPDPDRAGPSTLVRAG Q FLVDCGRGVLQRAAAVGVGAAGLSAVLLT
Sbjct  1    MIEITLLGTGSPIPDPDRAGPSTLVRAGGQVFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLITSWVTNFAADPAPL +IGPPGTAE V+A LKAFG DIGYRIAHHA
Sbjct  61   HLHSDHIAELGDVLITSWVTNFAADPAPLQVIGPPGTAETVDAMLKAFGRDIGYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DL  PPPIEVHEYT G  WDRDGV IRVAPTDHRPV PTIGFR+E DGAS VLAGDTVPC
Sbjct  121  DLNAPPPIEVHEYTDGTVWDRDGVAIRVAPTDHRPVAPTIGFRVEFDGASAVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
             SLD+LAAGA ALVHTVIRKDI+T  PQQRVKDICDYHSSVQEAAATA RAGVGTLVMTH
Sbjct  181  PSLDELAAGAGALVHTVIRKDIITNFPQQRVKDICDYHSSVQEAAATAARAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPR  272
            YVPAI  GQE+QWRALAATEF GRIE+GNDLHRVEVH R
Sbjct  241  YVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR  279


>gi|161350067|ref|NP_336961.2| ribonuclease Z [Mycobacterium tuberculosis CDC1551]
 gi|323719004|gb|EGB28153.1| hypothetical protein TMMG_01699 [Mycobacterium tuberculosis CDC1551A]
Length=241

 Score =  441 bits (1133),  Expect = 7e-122, Method: Compositional matrix adjust.
 Identities = 233/241 (97%), Positives = 234/241 (98%), Gaps = 7/241 (2%)

Query  40   VLQRAAAVGVGAAGLSAVLLTHLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAE  92
            +LQRAAAVGVGAAGLSAVLLTHLH       GDVLITSWVTNFAADPAPLPIIGPPGTAE
Sbjct  1    MLQRAAAVGVGAAGLSAVLLTHLHSDHIAELGDVLITSWVTNFAADPAPLPIIGPPGTAE  60

Query  93   VVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPT  152
            VVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPT
Sbjct  61   VVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPT  120

Query  153  IGFRIESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHS  212
            IGFRIESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHS
Sbjct  121  IGFRIESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHS  180

Query  213  SVQEAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPR  272
            SVQEAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPR
Sbjct  181  SVQEAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPR  240

Query  273  R  273
            R
Sbjct  241  R  241


>gi|118618938|ref|YP_907270.1| ribonuclease Z [Mycobacterium ulcerans Agy99]
 gi|166991492|sp|A0PTY0.1|RNZ_MYCUA RecName: Full=Ribonuclease Z; Short=RNase Z; AltName: Full=tRNA 
3 endonuclease; AltName: Full=tRNase Z
 gi|118571048|gb|ABL05799.1| metal-dependent hydrolase [Mycobacterium ulcerans Agy99]
Length=279

 Score =  440 bits (1131),  Expect = 1e-121, Method: Compositional matrix adjust.
 Identities = 240/279 (87%), Positives = 247/279 (89%), Gaps = 7/279 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+EITLLGTGSPIPDPDRAGPSTLVRAG Q FLVDCGRGVLQRAAAVGVGAAGLSAVLLT
Sbjct  1    MIEITLLGTGSPIPDPDRAGPSTLVRAGGQVFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLITSWVTNFAADPAPL +IGPPGTAE VEA LKAFG DIGYRIAHHA
Sbjct  61   HLHSDHIAELGDVLITSWVTNFAADPAPLQVIGPPGTAETVEAMLKAFGRDIGYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DL  PPPIEVHEYT G  WDRDGV IRVAPTDHRPV PTIGFR+E DGAS VLAG TVPC
Sbjct  121  DLNAPPPIEVHEYTDGTVWDRDGVAIRVAPTDHRPVAPTIGFRVEFDGASAVLAGGTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
             SLD+LAAGA ALVHTVIRKDI+T  PQQRVKDICDYHSSVQEAAATA RAGVGTLVMTH
Sbjct  181  PSLDELAAGAGALVHTVIRKDIITNFPQQRVKDICDYHSSVQEAAATAARAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPR  272
            YVPAI  GQE+QWRALAATEF GRIE+GNDLHRVEVH R
Sbjct  241  YVPAIIAGQEDQWRALAATEFGGRIELGNDLHRVEVHAR  279


>gi|13882195|gb|AAK46775.1| arylsulfatase, putative [Mycobacterium tuberculosis CDC1551]
Length=224

 Score =  430 bits (1106),  Expect = 9e-119, Method: Compositional matrix adjust.
 Identities = 216/224 (97%), Positives = 217/224 (97%), Gaps = 7/224 (3%)

Query  57   VLLTHLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRI  109
            +LLTHLH       GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRI
Sbjct  1    MLLTHLHSDHIAELGDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRI  60

Query  110  AHHADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGD  169
            AHHADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGD
Sbjct  61   AHHADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGD  120

Query  170  TVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTL  229
            TVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTL
Sbjct  121  TVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTL  180

Query  230  VMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  273
            VMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR
Sbjct  181  VMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPRR  224


>gi|254818757|ref|ZP_05223758.1| ribonuclease Z [Mycobacterium intracellulare ATCC 13950]
Length=280

 Score =  416 bits (1070),  Expect = 2e-114, Method: Compositional matrix adjust.
 Identities = 225/276 (82%), Positives = 242/276 (88%), Gaps = 7/276 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+E+TLLGTGSPIPDP+RAGPSTLVRAG Q FL DCGRGVLQRAAAVGVGAAGLSA+LLT
Sbjct  1    MIEVTLLGTGSPIPDPNRAGPSTLVRAGGQVFLADCGRGVLQRAAAVGVGAAGLSALLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLIT W++ F  DPAPLPIIGPPGTAE+VEATLKAF HDIGYRIAHHA
Sbjct  61   HLHSDHVGDLGDVLITRWISTFTPDPAPLPIIGPPGTAELVEATLKAFHHDIGYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DL  PP +EVHEYT GP WDRDGV+IRV  TDHRPV PTIGFRIE +GASVVLAGDTVPC
Sbjct  121  DLNAPPAVEVHEYTDGPVWDRDGVSIRVGATDHRPVAPTIGFRIEYEGASVVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
             SLD+LAAGA ALVHTVIRKDIV  IPQQR+ DICDYHSSV+EAAATA RAGVGTLVMTH
Sbjct  181  ASLDELAAGAGALVHTVIRKDIVAAIPQQRLVDICDYHSSVEEAAATAARAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEV  269
            YVPA+ PGQEEQWRALAA +F GRIE+G DLHRV+V
Sbjct  241  YVPALVPGQEEQWRALAAEQFGGRIELGYDLHRVQV  276


>gi|342857805|ref|ZP_08714461.1| ribonuclease Z [Mycobacterium colombiense CECT 3035]
 gi|342135138|gb|EGT88304.1| ribonuclease Z [Mycobacterium colombiense CECT 3035]
Length=280

 Score =  408 bits (1049),  Expect = 4e-112, Method: Compositional matrix adjust.
 Identities = 219/276 (80%), Positives = 240/276 (87%), Gaps = 7/276 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+E+TLLGTGSPIPDP+RAGPSTLV+AG Q FLVDCGRGVLQRAA+VGVGAAGL+A+LLT
Sbjct  1    MIEVTLLGTGSPIPDPNRAGPSTLVQAGGQVFLVDCGRGVLQRAASVGVGAAGLTALLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLIT W++ F  DPAPLPIIGPPGTAE V ATL AF HDIGYRIAHH+
Sbjct  61   HLHSDHIGDLGDVLITRWISTFTPDPAPLPIIGPPGTAEAVAATLNAFRHDIGYRIAHHS  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DL  PP ++VHEYT G  WDRDGV IRVAPTDHRPV PTIGFRIE  GAS VLAGDTVPC
Sbjct  121  DLNEPPAVDVHEYTEGAVWDRDGVAIRVAPTDHRPVAPTIGFRIEYQGASAVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
              LD+LAAGA ALVHTVIRKDIV  IPQQR++DICDYHSSV+EAAATA RAGVGTLVMTH
Sbjct  181  AGLDELAAGAGALVHTVIRKDIVVNIPQQRLQDICDYHSSVEEAAATAARAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEV  269
            YVPA+ PGQEEQWRALAAT+F GRIE+G+DLHRV+V
Sbjct  241  YVPALVPGQEEQWRALAATQFGGRIELGDDLHRVQV  276


>gi|41408318|ref|NP_961154.1| ribonuclease Z [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|56749440|sp|Q73XT9.1|RNZ_MYCPA RecName: Full=Ribonuclease Z; Short=RNase Z; AltName: Full=tRNA 
3 endonuclease; AltName: Full=tRNase Z
 gi|41396674|gb|AAS04537.1| hypothetical protein MAP_2220 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336458246|gb|EGO37227.1| metal-dependent hydrolase, beta-lactamase superfamily III [Mycobacterium 
avium subsp. paratuberculosis S397]
Length=280

 Score =  404 bits (1039),  Expect = 6e-111, Method: Compositional matrix adjust.
 Identities = 217/276 (79%), Positives = 239/276 (87%), Gaps = 7/276 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+E+TLLGTGSPIPDP+RAGPSTLVRAG Q FLVDCGRGVLQRAAA GVGAAGLSA+LLT
Sbjct  1    MIEVTLLGTGSPIPDPNRAGPSTLVRAGGQVFLVDCGRGVLQRAAAGGVGAAGLSALLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLIT W++ F  DP PLPIIGPPGTAE+V ATL A  HDIGYRIAHHA
Sbjct  61   HLHSDHVGDLGDVLITRWISTFTPDPVPLPIIGPPGTAELVAATLNALRHDIGYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DL  PP ++V E+T GP WDRDGV+IRVAPTDHRPV PTIGFR+E  GASVVLAGDTVPC
Sbjct  121  DLNAPPAVDVREHTDGPVWDRDGVSIRVAPTDHRPVAPTIGFRVEYQGASVVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
              LD+LAAGA ALVHTVIRKDIV  IPQQR++DICDYHSSV+EAAATA RAGVGTLVMTH
Sbjct  181  AGLDELAAGAGALVHTVIRKDIVATIPQQRLQDICDYHSSVEEAAATAARAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEV  269
            YVPA+  GQEEQWRALAA EF+GR+E+G+DLHRV+V
Sbjct  241  YVPALVAGQEEQWRALAAREFAGRVELGDDLHRVQV  276


>gi|333990144|ref|YP_004522758.1| metal-dependent hydrolase [Mycobacterium sp. JDM601]
 gi|333486112|gb|AEF35504.1| metal-dependent hydrolase [Mycobacterium sp. JDM601]
Length=285

 Score =  401 bits (1031),  Expect = 5e-110, Method: Compositional matrix adjust.
 Identities = 211/282 (75%), Positives = 235/282 (84%), Gaps = 11/282 (3%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT-  60
            +EITLLGTGSPIPDP+RAGPSTL+RAG QA LVDCGRGVLQR AA G  A  L+A+LLT 
Sbjct  3    IEITLLGTGSPIPDPNRAGPSTLIRAGGQALLVDCGRGVLQRLAAAGASANTLAALLLTH  62

Query  61   ----HLH--GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
                H+   GD+LIT WVT F  DPAPLPIIGPPGTA+VV A L+AFGHDIGYRIAHH D
Sbjct  63   LHSDHIADLGDLLITRWVTTFTPDPAPLPIIGPPGTADVVAAMLRAFGHDIGYRIAHHDD  122

Query  115  LTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIE----SDGASVVLAGDT  170
            LT PPP++V E+TAG  WDRDGV I VAPTDHRPVTPTIGFRIE    S  ASVV+AGDT
Sbjct  123  LTAPPPVDVQEHTAGQVWDRDGVRITVAPTDHRPVTPTIGFRIEHTDASGTASVVMAGDT  182

Query  171  VPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLV  230
            VPCDSLD+LAAGADALVHTVIR D++  +PQQR++DICDYHSSV +A ATA RAGVGTLV
Sbjct  183  VPCDSLDELAAGADALVHTVIRSDLIAALPQQRIRDICDYHSSVAQAGATARRAGVGTLV  242

Query  231  MTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPR  272
            +THYVPAI PGQEEQWRALAA EF G IE+G+DLHRV+V  R
Sbjct  243  LTHYVPAIAPGQEEQWRALAAAEFDGPIELGDDLHRVDVVAR  284


>gi|296170536|ref|ZP_06852120.1| ribonuclease Z [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295894768|gb|EFG74493.1| ribonuclease Z [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=279

 Score =  399 bits (1026),  Expect = 2e-109, Method: Compositional matrix adjust.
 Identities = 218/276 (79%), Positives = 240/276 (87%), Gaps = 7/276 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+EITLLGTGSPIPDP+RAGPSTLVRAG Q FLVDCGRGVLQRAAAVGVGAAGL+A+L+T
Sbjct  1    MIEITLLGTGSPIPDPNRAGPSTLVRAGGQVFLVDCGRGVLQRAAAVGVGAAGLTALLIT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GD+LIT W++ FA DPAPLPIIGPPG AE VEATL+AF HDI YRIAHHA
Sbjct  61   HLHSDHIGDLGDLLITRWISTFAPDPAPLPIIGPPGIAETVEATLQAFRHDIEYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DL  PP +EVHE T G  WDRDGV+IRVAPTDHRPVTPT+GFRI+   ASVVLAGDTVPC
Sbjct  121  DLNAPPAVEVHECTEGAVWDRDGVSIRVAPTDHRPVTPTVGFRIDHGTASVVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
              LD+LAAGA ALVHTVIRKDIV  IPQQR++DICDYHSSV+EAAATA RAGVGTLVMTH
Sbjct  181  PGLDRLAAGAGALVHTVIRKDIVGNIPQQRLQDICDYHSSVEEAAATAARAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEV  269
            YVPA   GQEEQWRALAA++F GRIE+G+DLHRVE+
Sbjct  241  YVPAPVAGQEEQWRALAASQFGGRIELGDDLHRVEI  276


>gi|120404862|ref|YP_954691.1| ribonuclease Z [Mycobacterium vanbaalenii PYR-1]
 gi|119957680|gb|ABM14685.1| beta-lactamase domain protein [Mycobacterium vanbaalenii PYR-1]
Length=300

 Score =  395 bits (1016),  Expect = 3e-108, Method: Compositional matrix adjust.
 Identities = 210/278 (76%), Positives = 234/278 (85%), Gaps = 7/278 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+E+TLLGTGSPIPD  RAGPSTLVRAG Q FLVDCGRGVLQR AAVGVGA  ++A+LLT
Sbjct  15   MIEVTLLGTGSPIPDARRAGPSTLVRAGGQTFLVDCGRGVLQRLAAVGVGANNITALLLT  74

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLIT WV+NFA D APLPIIGPPGTAEVVE TLKAFG DIGYRIAHHA
Sbjct  75   HLHSDHIADLGDVLITRWVSNFAPDLAPLPIIGPPGTAEVVENTLKAFGFDIGYRIAHHA  134

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DLTTPPP+EV E T G  W RD V+IRV PTDHRPVTPTIGFRIE +GASVVLAGDTVPC
Sbjct  135  DLTTPPPVEVEEVTEGVVWGRDEVSIRVGPTDHRPVTPTIGFRIEHNGASVVLAGDTVPC  194

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
              LD+LAAGA ALVHTVIR D++  +P QR++DICDYHSSV++AA TA RAGVG L++TH
Sbjct  195  RGLDELAAGAGALVHTVIRPDLIEAMPVQRIRDICDYHSSVEQAADTATRAGVGILILTH  254

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHP  271
            YVP + PGQEE WRALAA+ F  +IE+G+DLHRVEVHP
Sbjct  255  YVPTLQPGQEEDWRALAASVFDRQIEIGDDLHRVEVHP  292


>gi|145223256|ref|YP_001133934.1| ribonuclease Z [Mycobacterium gilvum PYR-GCK]
 gi|315443716|ref|YP_004076595.1| metal-dependent hydrolase, beta-lactamase superfamily III [Mycobacterium 
sp. Spyr1]
 gi|189043787|sp|A4T2G4.1|RNZ_MYCGI RecName: Full=Ribonuclease Z; Short=RNase Z; AltName: Full=tRNA 
3 endonuclease; AltName: Full=tRNase Z
 gi|145215742|gb|ABP45146.1| beta-lactamase-like protein [Mycobacterium gilvum PYR-GCK]
 gi|315262019|gb|ADT98760.1| metal-dependent hydrolase, beta-lactamase superfamily III [Mycobacterium 
sp. Spyr1]
Length=286

 Score =  392 bits (1008),  Expect = 3e-107, Method: Compositional matrix adjust.
 Identities = 207/278 (75%), Positives = 231/278 (84%), Gaps = 7/278 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+E+TLLGTGSPIPD  RAGPSTLVRAG Q FLVDCGRGVLQRAAAVGVGA  +SA+LLT
Sbjct  1    MIEVTLLGTGSPIPDARRAGPSTLVRAGGQTFLVDCGRGVLQRAAAVGVGANQISALLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLIT WV+NFA D  PLPIIGPPGTAEVVE  LKAF  DIGYRIAHH 
Sbjct  61   HLHSDHIADLGDVLITRWVSNFAPDLPPLPIIGPPGTAEVVENMLKAFSFDIGYRIAHHD  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DLTTPPP+EV E T G  W RD V+IRV PTDHRPVTPTIGFRIE  GASVVLAGDTVPC
Sbjct  121  DLTTPPPVEVEEVTDGVVWGRDEVSIRVGPTDHRPVTPTIGFRIEHHGASVVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
              LD+LAAGA ALVHTVIR+D++  +P QR++DICDYHSSV++AA TA RAGVG L++TH
Sbjct  181  RGLDKLAAGAGALVHTVIRRDLIEALPMQRIRDICDYHSSVEQAAETATRAGVGILILTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHP  271
            YVP + PGQE+ WRALAAT F  +IE+G+DLHRV+VHP
Sbjct  241  YVPTLQPGQEDDWRALAATRFDRQIEIGDDLHRVQVHP  278


>gi|118468499|ref|YP_888836.1| ribonuclease Z [Mycobacterium smegmatis str. MC2 155]
 gi|118169786|gb|ABK70682.1| ribonuclease Z [Mycobacterium smegmatis str. MC2 155]
Length=286

 Score =  390 bits (1002),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 211/278 (76%), Positives = 232/278 (84%), Gaps = 7/278 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+E+TLLGTGSPIPDPDRAGPST+VRAG Q FLVDCGRGVLQR AA G  A+ LSA+LLT
Sbjct  1    MIEVTLLGTGSPIPDPDRAGPSTMVRAGGQTFLVDCGRGVLQRLAAAGSSASQLSALLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDV+IT WV+ F  D  PLPIIGPPGTAEVVEATLKAFGHDIGYRIAHH 
Sbjct  61   HLHSDHIADLGDVIITRWVSTFTPDAPPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHD  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DLT PPP+EVHE+T G  WDRDGV IRV PTDHRPVTPTI FR+E   ASVV AGD+VPC
Sbjct  121  DLTAPPPVEVHEHTEGVVWDRDGVVIRVGPTDHRPVTPTIAFRVEHADASVVAAGDSVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
             +LD LA GA AL+HTVIRKDI+  +PQQR++DICDYHSSVQEAAATA RAGVG L++TH
Sbjct  181  ATLDALATGAGALIHTVIRKDIIETLPQQRIRDICDYHSSVQEAAATAARAGVGILILTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHP  271
            YVPAI PG E+QWR LAATEF  +IEVG DLHRVEVHP
Sbjct  241  YVPAIAPGTEDQWRELAATEFDRQIEVGADLHRVEVHP  278


>gi|118466889|ref|YP_880999.1| ribonuclease Z [Mycobacterium avium 104]
 gi|254774593|ref|ZP_05216109.1| ribonuclease Z [Mycobacterium avium subsp. avium ATCC 25291]
 gi|166991487|sp|A0QDL1.1|RNZ_MYCA1 RecName: Full=Ribonuclease Z; Short=RNase Z; AltName: Full=tRNA 
3 endonuclease; AltName: Full=tRNase Z
 gi|118168176|gb|ABK69073.1| ribonuclease Z [Mycobacterium avium 104]
Length=280

 Score =  380 bits (977),  Expect = 9e-104, Method: Compositional matrix adjust.
 Identities = 216/276 (79%), Positives = 239/276 (87%), Gaps = 7/276 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+E+TLLGTGSPIPDP+RAGPSTLVRAG Q FLVDCGRGVLQRAAAVGVGAAGLS +LLT
Sbjct  1    MIEVTLLGTGSPIPDPNRAGPSTLVRAGGQVFLVDCGRGVLQRAAAVGVGAAGLSTLLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GDVLIT WV+ F  DP PLPIIGPPGTAE+V ATL A  HDIGYRIAHHA
Sbjct  61   HLHSDHVGDLGDVLITRWVSTFTPDPVPLPIIGPPGTAELVAATLNALRHDIGYRIAHHA  120

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DL  PP ++V E+T GP WDRDGV+IRVAPTDHRPV PTIGFR++  GASVVLAGDTVPC
Sbjct  121  DLNAPPAVDVREHTDGPVWDRDGVSIRVAPTDHRPVAPTIGFRVDYQGASVVLAGDTVPC  180

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
              LD+LAAGA ALVHTVIRKDIV  IPQQR++DICDYHSSV++AAATA RAGVGTLVMTH
Sbjct  181  AGLDELAAGAGALVHTVIRKDIVATIPQQRLQDICDYHSSVEQAAATAARAGVGTLVMTH  240

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEV  269
            YVPA+  GQEEQWRALAA EF+GR+E+G+DLHRV+V
Sbjct  241  YVPALVAGQEEQWRALAAREFAGRVELGDDLHRVQV  276


>gi|108800472|ref|YP_640669.1| ribonuclease Z [Mycobacterium sp. MCS]
 gi|119869610|ref|YP_939562.1| ribonuclease Z [Mycobacterium sp. KMS]
 gi|126436095|ref|YP_001071786.1| ribonuclease Z [Mycobacterium sp. JLS]
 6 more sequence titles
 Length=285

 Score =  362 bits (929),  Expect = 3e-98, Method: Compositional matrix adjust.
 Identities = 200/278 (72%), Positives = 221/278 (80%), Gaps = 8/278 (2%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            M+E+TLLGTGSP+PD  RAGPSTLVRAG  AFLVDCGRGV  R AA G+ A GLSA+LLT
Sbjct  1    MIEVTLLGTGSPVPDARRAGPSTLVRAGGHAFLVDCGRGVQLRMAAAGIAANGLSALLLT  60

Query  61   HLH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            HLH       GD+LIT WVT F  D  PL IIGPPGTAE V A L AFG DIGYRIAHH 
Sbjct  61   HLHSDHIADLGDLLITRWVTTFT-DQVPLQIIGPPGTAETVTAMLAAFGRDIGYRIAHHP  119

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
            DLT PPP+EVHE T G AWD DGVT+RVAPTDHRPV PTIGFR+E   ASVVLAGDTVPC
Sbjct  120  DLTAPPPVEVHEVTEGVAWDHDGVTVRVAPTDHRPVAPTIGFRVEHADASVVLAGDTVPC  179

Query  174  DSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTH  233
             +LD LAAGA ALVHT IRKD+V   PQQRV+++C+YHSSV+EAA TA RAGVG LV+TH
Sbjct  180  ATLDALAAGAGALVHTAIRKDLVELAPQQRVREVCEYHSSVEEAAETAERAGVGILVLTH  239

Query  234  YVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHP  271
            Y+P I PGQE  WRA AAT F  +IE+G+DLHRVEVHP
Sbjct  240  YLPPIAPGQEADWRARAATAFPRQIELGDDLHRVEVHP  277


>gi|41017532|sp|Q49744.2|RNZ_MYCLE RecName: Full=Putative ribonuclease Z; Short=RNase Z; Short=tRNase 
Z; AltName: Full=tRNA 3 endonuclease
 gi|2398684|emb|CAB16144.1| hypothetical protein MLCL536.01 [Mycobacterium leprae]
Length=220

 Score =  194 bits (492),  Expect = 1e-47, Method: Compositional matrix adjust.
 Identities = 115/187 (62%), Positives = 128/187 (69%), Gaps = 10/187 (5%)

Query  25   VRAGAQAFLVDCGRGVLQRAAAVGVGA-AGLSAVLLTHLHGD-------VLITSWVTNFA  76
            ++AG Q FLVDC  GVLQRA+A      A       THLHGD       +LIT WVT FA
Sbjct  1    MQAGRQLFLVDCWLGVLQRASAGPTHTPAVCQRCCSTHLHGDRISDLGDLLITHWVTTFA  60

Query  77   ADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTAG-PAWDRD  135
             DP PLPIIG P TAE VEA LKA GHDI Y+I HH  L TPP IEV+EYT G      D
Sbjct  61   LDPPPLPIIGSPDTAETVEAKLKASGHDIEYQITHHTYLNTPPLIEVYEYTKGFVGAPPD  120

Query  136  GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDI  195
            GV+IR   T+H PVTPTIGFRIES   SVVL G TVPC SLD+LAA ADALVHT+IRK+I
Sbjct  121  GVSIR-GSTNHGPVTPTIGFRIESGPTSVVLTGGTVPCASLDELAAEADALVHTIIRKNI  179

Query  196  VTQIPQQ  202
            V ++ QQ
Sbjct  180  VIRVHQQ  186


>gi|466962|gb|AAA17148.1| B1937_C1_163 [Mycobacterium leprae]
Length=211

 Score =  182 bits (461),  Expect = 6e-44, Method: Compositional matrix adjust.
 Identities = 108/178 (61%), Positives = 121/178 (68%), Gaps = 10/178 (5%)

Query  34   VDCGRGVLQRAAAVGVGAAGLSA-VLLTHLHGD-------VLITSWVTNFAADPAPLPII  85
            +DC  GVLQRA+A       +      THLHGD       +LIT WVT FA DP PLPII
Sbjct  1    MDCWLGVLQRASAGPTHTPAVCQRCCSTHLHGDRISDLGDLLITHWVTTFALDPPPLPII  60

Query  86   GPPGTAEVVEATLKAFGHDIGYRIAHHADLTTPPPIEVHEYTAG-PAWDRDGVTIRVAPT  144
            G P TAE VEA LKA GHDI Y+I HH  L TPP IEV+EYT G      DGV+IR   T
Sbjct  61   GSPDTAETVEAKLKASGHDIEYQITHHTYLNTPPLIEVYEYTKGFVGAPPDGVSIR-GST  119

Query  145  DHRPVTPTIGFRIESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQ  202
            +H PVTPTIGFRIES   SVVL G TVPC SLD+LAA ADALVHT+IRK+IV ++ QQ
Sbjct  120  NHGPVTPTIGFRIESGPTSVVLTGGTVPCASLDELAAEADALVHTIIRKNIVIRVHQQ  177


>gi|197105711|ref|YP_002131088.1| metallo-beta-lactamase family protein [Phenylobacterium zucineum 
HLK1]
 gi|196479131|gb|ACG78659.1| metallo-beta-lactamase family protein [Phenylobacterium zucineum 
HLK1]
Length=362

 Score =  157 bits (396),  Expect = 2e-36, Method: Compositional matrix adjust.
 Identities = 104/288 (37%), Positives = 143/288 (50%), Gaps = 28/288 (9%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            L + L G GSP+PDP RAGP T V AG Q F+VD G G ++  + +    A + A L+TH
Sbjct  54   LHVGLCGAGSPMPDPTRAGPCTAVLAGRQLFIVDAGAGSVKNLSLMNFPPARVDAALITH  113

Query  62   LH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H       G++++  W     A PAPLP+ GP G  +VV+    A+G D GYRIAHH  
Sbjct  114  FHSDHIDGLGELMLQRWAGG--AWPAPLPVYGPTGVEQVVDGFEAAYGPDRGYRIAHHGP  171

Query  115  LTTPPP---IEVHEYTAGPA----WDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLA  167
              TPP     +   +  G       D+ G+ +   P  H P  P +G+R +  G SVV++
Sbjct  172  QVTPPSGFGGDPRPFAPGAQDVVLIDQPGLRVTAFPVPHSPAEPAVGYRFDYKGRSVVIS  231

Query  168  GDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVK-----------DICDYHSSVQE  216
            GDT     L+  A GAD LVH  +   +V    +   K           DI  YH++ +E
Sbjct  232  GDTAASPRLEAAARGADLLVHEGLSPKLVALQGRSADKGGKANLSHILHDIPSYHATPEE  291

Query  217  AAATANRAGVGTLVMTHYVPAIG-PGQEEQWRALAATEFSGRIEVGND  263
             A  A RAGV  L+ TH +P +     E  W   A   ++G I VG D
Sbjct  292  VAGIAQRAGVRYLLFTHVIPPLPIRALEGPWLGKAGKIYAGAIRVGRD  339


>gi|220916746|ref|YP_002492050.1| Ribonuclease Z [Anaeromyxobacter dehalogenans 2CP-1]
 gi|219954600|gb|ACL64984.1| Ribonuclease Z [Anaeromyxobacter dehalogenans 2CP-1]
Length=322

 Score =  148 bits (374),  Expect = 8e-34, Method: Compositional matrix adjust.
 Identities = 101/284 (36%), Positives = 143/284 (51%), Gaps = 18/284 (6%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            + +TLLGTG P P+ DR GPSTLV AG    L D GRGV QR   + +    + AV LTH
Sbjct  26   IRVTLLGTGRPAPEIDRFGPSTLVEAGGHRLLFDAGRGVTQRLWQLRIPLRDVDAVFLTH  85

Query  62   LHG-------DVLITSWV-TNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            LH        D+ +T W+ T F    APL + GP GT ++V A  +A+  D+  R  H  
Sbjct  86   LHSDHVVGLPDLWLTGWLPTPFGRRAAPLSLWGPAGTVDMVAALRRAYAWDLRARSGHQQ  145

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRP-VTPTIGFRIESDGASVVLAGDTVP  172
                   I   +   G  ++RDGV +     DH P + P +G+R++  G SV ++GDT P
Sbjct  146  LPEAGTTIRARDVKQGVVYERDGVKVTAFLVDHGPHLRPALGYRVDHAGRSVAISGDTRP  205

Query  173  CDSLDQLAAGADALVHTV--IRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLV  230
            C++L + AAG D LVH V   RK++V +     V+ I + H+S ++A     R      V
Sbjct  206  CENLVRFAAGTDVLVHEVAAARKELVER--SAVVRSILEVHTSPEDAGRVFTRVKPRLAV  263

Query  231  MTHYV-----PAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEV  269
             TH       P +         A   T ++G + VG DL  V +
Sbjct  264  FTHVALVTTDPDVPAPSVADIIARTRTTYAGPLVVGEDLMTVVI  307


>gi|167646632|ref|YP_001684295.1| ribonuclease Z [Caulobacter sp. K31]
 gi|167349062|gb|ABZ71797.1| beta-lactamase domain protein [Caulobacter sp. K31]
Length=364

 Score =  148 bits (373),  Expect = 1e-33, Method: Compositional matrix adjust.
 Identities = 101/293 (35%), Positives = 142/293 (49%), Gaps = 36/293 (12%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            L I L G G+PIPDP RAGP   V AG + F+VD G G  +  + + +  A + A+ LTH
Sbjct  54   LHIGLCGAGAPIPDPTRAGPCEAVLAGQRLFVVDAGAGGTKNLSLMNLPPARVEAIFLTH  113

Query  62   LH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H       G++++  W     A  +P+P+ GP G   VV   + A+  D GYRIAHH  
Sbjct  114  FHSDHIDGLGELMLQRW--GGGAATSPVPVYGPTGVDSVVNGFMAAYALDRGYRIAHHGP  171

Query  115  LTTPP--------PIEVHEYTAGPA---WDRDGVTIRVAPTDHRPVTPTIGFRIESDGAS  163
               PP        P  +    AGP     D  G+ +   P DH PV P +G+R +  G S
Sbjct  172  RVMPPSGFGGAPRPFAIDH--AGPNVVLIDDGGLKVTAFPVDHGPVEPAVGYRFDYKGRS  229

Query  164  VVLAGDTVPCDSLDQLAAGADALVHTVIRKDIV-----TQIPQQR------VKDICDYHS  212
            +V++GDT P   L+  A G D L H  +  D+V       +  +R        DI  YH+
Sbjct  230  LVISGDTAPSARLEATAKGVDLLAHEGLAPDLVAIQHRAAVAAKRDNLAAVTHDIPSYHT  289

Query  213  SVQEAAATANRAGVGTLVMTHYVPAIGPGQ--EEQWRALAATEFSGRIEVGND  263
            + + AA  A RAGV  L+  H +P + P +  E  W   +   F G + VG D
Sbjct  290  APEAAAGIAQRAGVRYLLFEHIIPPV-PFEALEGPWLGRSRRIFHGAVRVGRD  341


>gi|163792586|ref|ZP_02186563.1| ribonuclease Z [alpha proteobacterium BAL199]
 gi|159182291|gb|EDP66800.1| ribonuclease Z [alpha proteobacterium BAL199]
Length=295

 Score =  147 bits (372),  Expect = 1e-33, Method: Compositional matrix adjust.
 Identities = 98/284 (35%), Positives = 137/284 (49%), Gaps = 18/284 (6%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            +++TLLGTG P     R GP+ LVR G+ + LVDCG GV QR    G     L AVLLTH
Sbjct  1    MKVTLLGTGCPQCHTKRYGPANLVRHGSVSVLVDCGSGVTQRLVGAGSPGGKLDAVLLTH  60

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
            LH D       ++++ W         PL I GP GT   V+  L  +  +   RIAH   
Sbjct  61   LHSDHLVDLYQLIVSGW---HQGRTTPLRIYGPKGTRAYVDGLLALWKDERELRIAHEQR  117

Query  115  LTTPP-PIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIES-DGASVVLAGDTVP  172
             ++     EV EY  GP  D  G+++     DHRPV    GF   + DG++ V +GDT  
Sbjct  118  PSSAGFTAEVMEYAEGPVVDLPGLSVTAVKVDHRPVEEAYGFVFRADDGSTAVFSGDTRY  177

Query  173  CDSLDQLAAGADALVHTVIRKDIVTQIPQQR----VKDICDYHSSVQEAAATANRAGVGT  228
            C +L + A GAD L+H      ++  +P  R    +  +  YH+   E    A  A    
Sbjct  178  CPALIRAARGADVLIHECFIHGLMKPVPGMRTQVGIDAVASYHTLSAEVGKVATEAEARF  237

Query  229  LVMTHYVPAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEVHPR  272
            L++ H+VPA      E   A  A +F+G   +G DL   ++  R
Sbjct  238  LMLNHFVPA--EFDREALSAEVARDFTGPFAIGEDLMSYDIPTR  279


>gi|197121970|ref|YP_002133921.1| ribonuclease Z [Anaeromyxobacter sp. K]
 gi|196171819|gb|ACG72792.1| Ribonuclease Z [Anaeromyxobacter sp. K]
Length=323

 Score =  146 bits (368),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 101/284 (36%), Positives = 142/284 (50%), Gaps = 18/284 (6%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
              +TLLGTG P P+ DR GPSTLV AG    L D GRGV QR   + +    + AV LTH
Sbjct  27   FRVTLLGTGRPAPEIDRFGPSTLVEAGGHRLLFDAGRGVTQRLWQLRMPLRDIDAVFLTH  86

Query  62   LHG-------DVLITSWV-TNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHA  113
            LH        D+ +T W+ T F     PL + GP GT ++V A  +A+  D+  R  H  
Sbjct  87   LHSDHVVGIPDLWLTGWLPTPFGRRVVPLALWGPAGTVDMVAALRRAYAWDLRARSGHQQ  146

Query  114  DLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHRP-VTPTIGFRIESDGASVVLAGDTVP  172
                   +   +   G  ++RDGV +     DH P + P +G+R++  G SVV++GDT P
Sbjct  147  LPDAGATVRARDVGQGVVYERDGVKVTAFTVDHGPHLRPALGYRVDHAGRSVVISGDTRP  206

Query  173  CDSLDQLAAGADALVHTV--IRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLV  230
            C++L + AAGAD LVH V   RK++V +    R   I   H+S ++A     R      V
Sbjct  207  CENLVRFAAGADVLVHEVAAARKELVDRSAVAR--SILAVHTSPEDAGRVFTRVKPRLAV  264

Query  231  MTHYV-----PAIGPGQEEQWRALAATEFSGRIEVGNDLHRVEV  269
             TH       PA+      +  A     ++G + VG DL  V +
Sbjct  265  FTHVALLTTDPAVPAPSIAELVARTRETYAGPLVVGEDLMTVVI  308


>gi|149927436|ref|ZP_01915691.1| ribonuclease Z [Limnobacter sp. MED105]
 gi|149823928|gb|EDM83153.1| ribonuclease Z [Limnobacter sp. MED105]
Length=355

 Score =  145 bits (366),  Expect = 7e-33, Method: Compositional matrix adjust.
 Identities = 100/289 (35%), Positives = 140/289 (49%), Gaps = 29/289 (10%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            L + L GTGSP PDP RA P TLV AG   FL D G    ++ A +      L  V +TH
Sbjct  51   LHVGLCGTGSPFPDPQRAAPCTLVIAGKDMFLFDAGSAAAKQIANMNFSTGQLKGVFITH  110

Query  62   LH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
            LH       G+VL+T W  +   +   L + GP G + V+     A+  D GYR AHH  
Sbjct  111  LHSDHIDGLGEVLMTRWAQH--TEGQRLTVHGPTGVSNVLNGFKMAYEADNGYRTAHHGA  168

Query  115  LTTPPPI---EVHEYTAGPA-----WDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVL  166
             T PP +   +V+E+T           +  + I     +H+P+ P +G+RI   G +VVL
Sbjct  169  ATMPPELAGADVNEFTVQKGSTTTVLQQPDLLIEAFAVNHQPINPAVGYRIAYKGRTVVL  228

Query  167  AGDTVPCDSLDQLAAGADALVHTVIRKDIV-----TQIPQQRVK------DICDYHSSVQ  215
            +GDT   + +   A  AD LVH  +  ++V     T I  QR K      DI +YH+S  
Sbjct  229  SGDTTSDEQVKNAARKADLLVHEALSPELVARLQDTAIKNQRSKLAKIFSDIPNYHASPL  288

Query  216  EAAATANRAGVGTLVMTHYV-PAIGPGQEEQWRALAATEFSGRIEVGND  263
            + A  A  A VG +V++H V P   P  +E +   A   F G   +G D
Sbjct  289  DVAVLAQEAEVGHVVLSHIVPPLPLPPLKEIFLGKAPDVFQGPFRIGED  337


>gi|85708124|ref|ZP_01039190.1| metallo-beta-lactamase family protein [Erythrobacter sp. NAP1]
 gi|85689658|gb|EAQ29661.1| metallo-beta-lactamase family protein [Erythrobacter sp. NAP1]
Length=352

 Score =  143 bits (360),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 105/290 (37%), Positives = 144/290 (50%), Gaps = 32/290 (11%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            L + L GTGSP+P+PDRAGP  LV AG QA++VD G G  +    +G      +A+LLTH
Sbjct  48   LHLVLCGTGSPLPNPDRAGPCNLVVAGDQAYVVDIGEGGARNLNLMGYFIPSTTALLLTH  107

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       + +  W        APLP+ GP G   +VE   +A+  D  YR+ HH  
Sbjct  108  YHSDHVDGIGPLSLLYWTQ--GTKTAPLPVHGPQGLNVLVEGFNRAYELDRTYRVEHHTS  165

Query  115  LTTPP--------PIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVL  166
               P         P E+ E       +R G+ I     DH PV P++G+R +  G S+V+
Sbjct  166  EIVPETGGGLTAIPFEIGEQPV-TVIERGGLRITAFRVDHDPVRPSVGYRFDYKGRSIVI  224

Query  167  AGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQQR-----------VKDICDYHSSVQ  215
            +GD    DS+ + A GAD LVH  ++  +V  I                +DI DYH++ +
Sbjct  225  SGDAAKSDSIAKAARGADILVHDALQPRLVGHITDALDEAGNEAVATITRDILDYHATPE  284

Query  216  EAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATE--FSGRIEVGND  263
            EAA TA  AGV  L+++H VP I P        L   E  F G+I VG D
Sbjct  285  EAAETAQAAGVRHLILSHLVPPI-PNAFFYPAFLGDAEDAFDGKITVGED  333


>gi|254514783|ref|ZP_05126844.1| ribonuclease Z [gamma proteobacterium NOR5-3]
 gi|219677026|gb|EED33391.1| ribonuclease Z [gamma proteobacterium NOR5-3]
Length=375

 Score =  142 bits (359),  Expect = 4e-32, Method: Compositional matrix adjust.
 Identities = 93/274 (34%), Positives = 134/274 (49%), Gaps = 32/274 (11%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            L + L G G P+P P+ +GP   V AG + F+VD G   L+    +G  A  + AV LTH
Sbjct  69   LHLALCGAGGPLPAPNASGPCVAVVAGKRLFIVDAGTDGLRNLGRMGYAAGSIEAVFLTH  128

Query  62   LH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H       G++    WV+  AA+  PLP+ GP G  +VV     A+  D  YR AHH D
Sbjct  129  FHSDHIDGLGELATIRWVS--AANTEPLPVYGPMGVTQVVGGFNMAYALDEQYRHAHHGD  186

Query  115  LTTPPP---IEVHEYTAGPA-------WDRDGVTIRVAPTDHRPVTPTIGFRIESDGASV  164
               PP    +    + A PA       +D   + +     +H P+ P +G+R      S+
Sbjct  187  TVAPPSGAGMTAKPF-AAPATGTLTTLFDEADLKVEALAVNHAPIKPAVGYRFTYKDRSL  245

Query  165  VLAGDTVPCDSLDQLAAGADALVHTVIRKDIV-----------TQIPQQRVKDICDYHSS  213
            +++GDT   D++ Q + G D L+H  +  ++V            +I  +   DI DYH+S
Sbjct  246  LISGDTSKQDNIRQFSQGVDLLIHEALAPNLVNMMHEAAEAADNEILAKITHDILDYHTS  305

Query  214  VQEAAATANRAGVGTLVMTHYVPAI-GPGQEEQW  246
              EAA TA  AGVG L+  H VP I  PGQE  +
Sbjct  306  PVEAAETARDAGVGHLLYYHIVPPIVFPGQETLF  339


>gi|340788141|ref|YP_004753606.1| hydrolase [Collimonas fungivorans Ter331]
 gi|340553408|gb|AEK62783.1| hydrolase [Collimonas fungivorans Ter331]
Length=308

 Score =  139 bits (350),  Expect = 4e-31, Method: Compositional matrix adjust.
 Identities = 91/279 (33%), Positives = 138/279 (50%), Gaps = 21/279 (7%)

Query  3    EITLLGT-GSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            ++ LLGT G P P   RA P+ ++    Q ++VDCG GV  +    GV    +  + LTH
Sbjct  31   QLILLGTKGGPTPSALRAAPANVLLVDGQPYVVDCGNGVALQLTKAGVRLPQIRDIFLTH  90

Query  62   LH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H       G+++  +W T  A    P+ + GPPG  ++++  +     DI  R+     
Sbjct  91   QHSDHNADLGNLVFLAWATGLAT---PVHLYGPPGMRQMMDDFVHMNAIDIATRMQEEGR  147

Query  115  LTTPPPIEVHEYTAGP--AWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVP  172
                P I  HE+  GP    + D V +  A  DH  + PT  +R ++   SVV +GDT  
Sbjct  148  PPLRPLINTHEFD-GPRVVMENDQVKVTAALVDHYTLKPTFAYRFDTRDRSVVFSGDTAY  206

Query  173  CDSLDQLAAGADALVHTVIRKDIVTQIPQ------QRVKDICDYHSSVQEAAATANRAGV  226
             ++L QLA GAD LVH V+    + ++ +        +  +   H+S  +    A RAGV
Sbjct  207  NENLIQLAKGADVLVHEVMYLPALEKLMKTVDNAPTLLDHLVKSHTSTAQVGKVAARAGV  266

Query  227  GTLVMTHYVPAIGPG-QEEQWRALAATEFSGRIEVGNDL  264
             TLV++H+VP   P   ++ W A A  +FSG I VG DL
Sbjct  267  KTLVLSHFVPGGDPAISDDMWSAEARRQFSGEIIVGKDL  305


>gi|154251904|ref|YP_001412728.1| ribonuclease Z [Parvibaculum lavamentivorans DS-1]
 gi|154155854|gb|ABS63071.1| beta-lactamase domain protein [Parvibaculum lavamentivorans DS-1]
Length=381

 Score =  136 bits (343),  Expect = 3e-30, Method: Compositional matrix adjust.
 Identities = 95/281 (34%), Positives = 130/281 (47%), Gaps = 49/281 (17%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            L + L GTGSP+PDP RA   T V AG    ++D G G   R  A  + A  +  +L TH
Sbjct  56   LHVFLCGTGSPMPDPTRANACTAVIAGGHIVVIDTGPGSWSRIVAGKLPAGKIGTILFTH  115

Query  62   LH-------GDVLITSWVTNFAADPAPLPIIGP-------------------PGTAEVVE  95
            LH       G+  + SW+        PL + GP                    GT +VV 
Sbjct  116  LHSDHIGALGEFAVQSWI---GGRVVPLEVYGPGKLEGSVPPLNSLGHAYGSSGTVDVVR  172

Query  96   ATLKAFGHDIGYRIAHHA-DLTTPPPIEV--HEY------TAGPAWDRDGVTIRVAPTDH  146
               +AF  D GYRI HH  D  +P    +  HE       T  P +D+DG+ I     DH
Sbjct  173  GFAEAFDSDSGYRILHHGTDYLSPEGARIIGHEIARPAPNTLVPVFDKDGLQISAFLVDH  232

Query  147  RPVTPTIGFRIESDGASVVLAGDTVPCDSLDQLAAGADALVHTVIRKDIVTQIPQ-----  201
             PV P  G+R+E  G   +++GDT   +S++  + GAD LVH  +   + + I +     
Sbjct  233  HPVEPAFGYRVEYQGRVAIISGDTKRTESVELFSKGADLLVHEALNHSMSSIISEALTET  292

Query  202  ------QRVKDICDYHSSVQEAAATANRAGVGTLVMTHYVP  236
                  + V D  DYH+S  +AA  A  AGV  LV+TH VP
Sbjct  293  DNLRLAKMVHDTLDYHASPVDAAEIARDAGVPMLVLTHIVP  333


>gi|254490530|ref|ZP_05103716.1| metallo-beta-lactamase superfamily, putative [Methylophaga thiooxidans 
DMS010]
 gi|224464274|gb|EEF80537.1| metallo-beta-lactamase superfamily, putative [Methylophaga thiooxydans 
DMS010]
Length=295

 Score =  135 bits (340),  Expect = 6e-30, Method: Compositional matrix adjust.
 Identities = 92/278 (34%), Positives = 138/278 (50%), Gaps = 13/278 (4%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            L +TLLGTG+PIP  +R G STL+    + FL D GRG   R + +G+  + +  + LTH
Sbjct  24   LTVTLLGTGTPIPSIERFGSSTLIEHKGKYFLFDVGRGATIRLSQIGMYPSDIDNIFLTH  83

Query  62   LHGDVLI---TSWVTNFAADPA-PLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHADLTT  117
            LH D +      W+T      A  L + GP GT   VE T  AF  D  YR    +    
Sbjct  84   LHSDHITGFDDFWITGGIWQRANTLNVYGPDGTKSFVEHTQGAFSLDAFYREKQSSLNLK  143

Query  118  PPPIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPCDSLD  177
               + V E   G  +D DG+ +     DH  V    G+RI+SD  SV+++GDT   ++L 
Sbjct  144  GLEVNVTEIKEGLIYDEDGLKVSAFRVDHGAVEHAYGYRIDSDRHSVLISGDTTYSENLI  203

Query  178  QLAAGADALVH--TVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVMTHYV  235
              +   D L+H  +VI   ++   P  ++K I  YH+S+Q+      +      V+ H +
Sbjct  204  ANSQELDLLIHEVSVIEPKLLQSNP--KLKSISKYHTSLQQLHKLVEKVKPQKTVLNHLL  261

Query  236  PAIGPGQEEQWRALAATEFSGR-IEVGNDLHRVEVHPR  272
              IG   E +   L  T+F  + I+VG+DL  + +H R
Sbjct  262  -LIGS-DETELSHLLETKFQDKNIDVGHDL--MTIHLR  295


>gi|241663940|ref|YP_002982300.1| beta-lactamase domain-containing protein [Ralstonia pickettii 
12D]
 gi|240865967|gb|ACS63628.1| beta-lactamase domain protein [Ralstonia pickettii 12D]
Length=319

 Score =  134 bits (338),  Expect = 1e-29, Method: Compositional matrix adjust.
 Identities = 89/281 (32%), Positives = 138/281 (50%), Gaps = 19/281 (6%)

Query  3    EITLLGT-GSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGT G P P  +R+ P+ ++     +++VDCG GV ++    G+    +  V LTH
Sbjct  42   RLILLGTAGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVTAGLKLKDIRHVFLTH  101

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+      P+   GPP  A +    L+ + +DI  RIA    
Sbjct  102  QHSDHNADYGTLMLLAWATDLTG---PVDAWGPPPLAAMTTKFLELYDYDIRTRIADEGR  158

Query  115  LTTPPPIEVHEYTAGPAWDRD-GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P I  HE + G    +D  V +  A   H PV+P   FR +S   S+V++GDT P 
Sbjct  159  PPLAPMIHPHEISEGGLVMQDANVKVTSALVKHPPVSPAFAFRFDSADRSIVISGDTAPS  218

Query  174  DSLDQLAAGADALVHTVIR----KDIVTQIPQQRV--KDICDYHSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+       +++  P  +   + +   H+S +E    A  A V 
Sbjct  219  ENLVRLAYGADVLVHEVMHLPSLDKLLSTEPNAKTLREHLLASHTSTEEVGRIATEAKVK  278

Query  228  TLVMTHYVPAIGPGQEEQ-WRALAATEFSGRIEVGNDLHRV  267
            TLV++H+VP   P  E+  W       F G I VG+DL  +
Sbjct  279  TLVLSHFVPGGYPYLEDSVWLDAVRPHFKGEIIVGHDLQEI  319


>gi|16125428|ref|NP_419992.1| ribonuclease Z [Caulobacter crescentus CB15]
 gi|13422498|gb|AAK23160.1| metallo-beta-lactamase family protein [Caulobacter crescentus 
CB15]
Length=317

 Score =  134 bits (337),  Expect = 1e-29, Method: Compositional matrix adjust.
 Identities = 96/291 (33%), Positives = 144/291 (50%), Gaps = 32/291 (10%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            L + L G GSP+ DP R+GP   V AG   F+VD G G  +    + +    +SAV +TH
Sbjct  8    LHVGLCGAGSPMADPLRSGPCVAVVAGKDLFVVDSGSGSTRNLLLMNMPPPRVSAVFITH  67

Query  62   LH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H       G++++  W     A   P P+ GP G  +VV+   +A+  D GYRIAHH +
Sbjct  68   YHSDHIADLGELMLQRWAG--GASKTPTPVYGPQGLEQVVQGFEQAYTLDRGYRIAHHGE  125

Query  115  LTTPPP---IEVHEYTAGPA------WDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVV  165
               PP     +   + A PA       ++ G+ +   P  H PV   +G+R E  G SVV
Sbjct  126  AVAPPSGFGGDPRPFVADPAAPDVLVLEKPGLKVWAFPVAHHPVEGAVGYRFEYKGRSVV  185

Query  166  LAGDTVPCDSLDQLAAGADALVH-------TVIRKDIVTQIPQQR----VKDICDYHSSV  214
            ++GDT P + L + + GAD L+H         ++KD+  ++ +        DI DYH++ 
Sbjct  186  ISGDTGPSERLVKASKGADLLLHEGLAPNLVAVQKDVADKMGRDNYAKIFHDILDYHTAP  245

Query  215  QEAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATE--FSGRIEVGND  263
            + AA  A  AGVG L+  H +P + P +      L  +   F G I+VG D
Sbjct  246  EVAAEEAKAAGVGALMFYHIIPPL-PVRALDGPFLGRSREIFDGPIKVGRD  295


>gi|221234171|ref|YP_002516607.1| ribonuclease Z [Caulobacter crescentus NA1000]
 gi|220963343|gb|ACL94699.1| metal-dependent hydrolase [Caulobacter crescentus NA1000]
Length=363

 Score =  134 bits (337),  Expect = 2e-29, Method: Compositional matrix adjust.
 Identities = 96/291 (33%), Positives = 144/291 (50%), Gaps = 32/291 (10%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            L + L G GSP+ DP R+GP   V AG   F+VD G G  +    + +    +SAV +TH
Sbjct  54   LHVGLCGAGSPMADPLRSGPCVAVVAGKDLFVVDSGSGSTRNLLLMNMPPPRVSAVFITH  113

Query  62   LH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H       G++++  W     A   P P+ GP G  +VV+   +A+  D GYRIAHH +
Sbjct  114  YHSDHIADLGELMLQRWAGG--ASKTPTPVYGPQGLEQVVQGFEQAYTLDRGYRIAHHGE  171

Query  115  LTTPPP---IEVHEYTAGPA------WDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVV  165
               PP     +   + A PA       ++ G+ +   P  H PV   +G+R E  G SVV
Sbjct  172  AVAPPSGFGGDPRPFVADPAAPDVLVLEKPGLKVWAFPVAHHPVEGAVGYRFEYKGRSVV  231

Query  166  LAGDTVPCDSLDQLAAGADALVH-------TVIRKDIVTQIPQQR----VKDICDYHSSV  214
            ++GDT P + L + + GAD L+H         ++KD+  ++ +        DI DYH++ 
Sbjct  232  ISGDTGPSERLVKASKGADLLLHEGLAPNLVAVQKDVADKMGRDNYAKIFHDILDYHTAP  291

Query  215  QEAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAATE--FSGRIEVGND  263
            + AA  A  AGVG L+  H +P + P +      L  +   F G I+VG D
Sbjct  292  EVAAEEAKAAGVGALMFYHIIPPL-PVRALDGPFLGRSREIFDGPIKVGRD  341


>gi|187929827|ref|YP_001900314.1| beta-lactamase domain-containing protein [Ralstonia pickettii 
12J]
 gi|187726717|gb|ACD27882.1| beta-lactamase domain protein [Ralstonia pickettii 12J]
Length=321

 Score =  133 bits (335),  Expect = 2e-29, Method: Compositional matrix adjust.
 Identities = 89/281 (32%), Positives = 139/281 (50%), Gaps = 19/281 (6%)

Query  3    EITLLGT-GSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGT G P P  +R+ P+ ++     +++VDCG GV ++    G+    +  V +TH
Sbjct  44   RLILLGTAGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVTAGLKLKDIRHVFITH  103

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+      P+   GPP  A +    L+ + +DI  RIA    
Sbjct  104  QHSDHNADYGTLMLLAWATDLTG---PVDAWGPPPLAAMTTKFLELYDYDIRTRIADEGR  160

Query  115  LTTPPPIEVHEYTAGPAWDRD-GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P +  HE T G    +D  V +  A   H PV+P   FR +S   S+V++GDT P 
Sbjct  161  PPLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAFRFDSADRSIVISGDTAPS  220

Query  174  DSLDQLAAGADALVHTVIR-----KDIVTQIPQQRVKD-ICDYHSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+      K + T+   + +++ +   H+S +E    A  A V 
Sbjct  221  ENLVRLAYGADVLVHEVMHLPSLDKLLSTEPNAKTLREHLLASHTSTEEVGRIATEAKVK  280

Query  228  TLVMTHYVPAIGPGQEEQ-WRALAATEFSGRIEVGNDLHRV  267
            TLV++H+VP   P  E+  W       F G I VG DL  +
Sbjct  281  TLVLSHFVPGGYPYLEDSVWLDAVRPHFKGEIIVGRDLQEI  321


>gi|309781470|ref|ZP_07676206.1| hydrolase [Ralstonia sp. 5_7_47FAA]
 gi|308919883|gb|EFP65544.1| hydrolase [Ralstonia sp. 5_7_47FAA]
Length=319

 Score =  133 bits (335),  Expect = 2e-29, Method: Compositional matrix adjust.
 Identities = 89/281 (32%), Positives = 137/281 (49%), Gaps = 19/281 (6%)

Query  3    EITLLGT-GSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGT G P P  +R+ P+ ++     +++VDCG GV ++    G+    +  V LTH
Sbjct  42   RLILLGTAGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVTAGLKLKDIRHVFLTH  101

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+      P+   GPP  A +    L+ + +DI  RIA    
Sbjct  102  QHSDHNADYGTLMLLAWATDLTG---PVDAWGPPPLAAMTTKFLELYDYDIRTRIADEGR  158

Query  115  LTTPPPIEVHEYTAGPAWDRD-GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P I  HE + G    +D  V +  A   H PV+P   FR +S   S+V++GDT P 
Sbjct  159  PPLAPMIHPHEISEGGLVMQDANVKVTSALVKHPPVSPAFAFRFDSADRSIVISGDTAPS  218

Query  174  DSLDQLAAGADALVHTVIR----KDIVTQIPQQRV--KDICDYHSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+       +++  P  +   + +   H+S  E    A  A V 
Sbjct  219  ENLVRLAYGADVLVHEVMHLPSLDKLLSTEPNAKTLREHLLASHTSTDEVGRIATEAKVK  278

Query  228  TLVMTHYVPAIGPGQEEQ-WRALAATEFSGRIEVGNDLHRV  267
            TLV++H+VP   P  E+  W       F G I VG+DL  +
Sbjct  279  TLVLSHFVPGGYPYLEDSVWLDAVRPHFKGEIIVGHDLQEI  319


>gi|114799524|ref|YP_760010.1| ribonuclease Z [Hyphomonas neptunium ATCC 15444]
 gi|114739698|gb|ABI77823.1| metallo-beta-lactamase family protein [Hyphomonas neptunium ATCC 
15444]
Length=362

 Score =  130 bits (327),  Expect = 2e-28, Method: Compositional matrix adjust.
 Identities = 101/292 (35%), Positives = 144/292 (50%), Gaps = 33/292 (11%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            L + + G+GSP+PD  RAGP   V AG +AF+ D G G ++R   +G        + L+H
Sbjct  54   LHLYVCGSGSPLPDAARAGPCIGVLAGDRAFIFDVGAGSIRRLTRMGFPTGRTEKLYLSH  113

Query  62   LH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
            LH       G+++I +WV    +  APLP+ GP G AEV+     A+  D  YR+AHH  
Sbjct  114  LHSDHFDGIGELMIGAWVG--GSRSAPLPVAGPEGVAEVMNGFNAAYRIDSTYRMAHHGP  171

Query  115  LTTPP-----PIEVHEYTAGPA-----WDRDGVTIRVAPTDHRPVTPTIGFRIESDGASV  164
                P       EV +  AGP       D   + I     +H P+ P  GFRI+  G S 
Sbjct  172  GVANPDGYGLAPEVIDLPAGPGSRAVLLDEGDLLITAFLVNHSPIEPAYGFRIDYKGRSA  231

Query  165  VLAGDTVPCDSLDQLAAGADALVHTVIRKDIV----------TQIPQQRV-KDICDYHSS  213
            V++GDTV  ++L  ++ GAD L H  +  ++V             P  +V  DI +YH+S
Sbjct  232  VISGDTVYSENLVAVSEGADILFHEALHPEMVAAMSSAAAEAGAAPLSKVFSDILNYHAS  291

Query  214  VQEAAATANRAGVGTLVMTHYVPAIGPGQEEQWRALAAT--EFSGRIEVGND  263
              EAA  A  AG G LV+ H VP + P +      L  T   FSG +++  D
Sbjct  292  PVEAARAAQSAGAGRLVLYHTVPPL-PSKLLYPYFLDGTGEAFSGPVDIAED  342


>gi|119474698|ref|ZP_01615051.1| ribonuclease Z [marine gamma proteobacterium HTCC2143]
 gi|119450901|gb|EAW32134.1| ribonuclease Z [marine gamma proteobacterium HTCC2143]
Length=347

 Score =  129 bits (325),  Expect = 4e-28, Method: Compositional matrix adjust.
 Identities = 88/258 (35%), Positives = 125/258 (49%), Gaps = 24/258 (9%)

Query  2    LEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
            LE+ + G+ SP+PDP RA    +VRAG + FLVD G G  +     GV    +  +LLTH
Sbjct  52   LEVMVCGSSSPLPDPSRAQACIMVRAGNRIFLVDAGSGSAEVLRLEGVPMQLIGTILLTH  111

Query  62   LH-------GDVLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H        DV + SWV   A  PA L I+GP G   VV     A+G D  YR AHH +
Sbjct  112  FHSDHISAIADVNLGSWV---AGRPARLQIVGPEGVNSVVAGFNLAYGLDRSYRTAHHGE  168

Query  115  LTTPP---PIEVHEYTAGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTV  171
               P     ++    T G  +  D +TI     DH P++P +G+R +  G SVV+ GDT+
Sbjct  169  DFLPSVLGALQAQTITPGVIYAEDELTITAFEVDHAPISPAVGYRFDYMGRSVVVTGDTI  228

Query  172  PCDSLDQLAAGADALVHTVIRKDIVTQIPQ-----------QRVKDICDYHSSVQEAAAT  220
                ++  A  AD L+   +  D++  + +             +KDI DYH+  +     
Sbjct  229  VTKGIEVAAKDADLLLTDALSHDLINAMSEGAAAGGMDRGATILKDIMDYHADTKNIGKM  288

Query  221  ANRAGVGTLVMTHYVPAI  238
            A  AGVG +   H VP +
Sbjct  289  AAAAGVGQVAFYHLVPPV  306


>gi|299065910|emb|CBJ37090.1| putative arylsulfatase (Aryl-sulfate sulphohydrolase) [Ralstonia 
solanacearum CMR15]
Length=320

 Score =  128 bits (321),  Expect = 1e-27, Method: Compositional matrix adjust.
 Identities = 86/278 (31%), Positives = 139/278 (50%), Gaps = 19/278 (6%)

Query  3    EITLLGTGS-PIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGTG  P P  +R+ P+ ++     +++VDCG GV ++  + G+    +  V +TH
Sbjct  43   RLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVSAGLKLKAIRHVFITH  102

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+      P+   GPP  AE+    L+ + +DI  RIA    
Sbjct  103  QHSDHNADYGALMLLAWGTDLTG---PVDTWGPPPLAEMTTKFLELYDYDIRTRIADEGR  159

Query  115  LTTPPPIEVHEYTAGPAWDRD-GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P +  HE T G    +D  V +  A   H PV+P   +R ++   S+V++GDT P 
Sbjct  160  PPLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPS  219

Query  174  DSLDQLAAGADALVHTVIR-----KDIVTQIPQQRVKD-ICDYHSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+      K + T+     +++ +   H+S ++    A  A V 
Sbjct  220  ENLVRLAHGADVLVHEVMHLPSLDKLLATERNATTLREHLLASHTSAEDVGRIATEAKVK  279

Query  228  TLVMTHYVPAIGPGQEEQ-WRALAATEFSGRIEVGNDL  264
            TLV++H+VP   P  ++  W       F G I VG DL
Sbjct  280  TLVLSHFVPGGYPYLDDAVWLDAVRPHFKGEIIVGRDL  317


>gi|334195076|gb|AEG68261.1| arylsulfatase precursor (aryl-sulfate sulfohydrolase) protein 
[Ralstonia solanacearum Po82]
Length=321

 Score =  127 bits (320),  Expect = 1e-27, Method: Compositional matrix adjust.
 Identities = 85/278 (31%), Positives = 138/278 (50%), Gaps = 19/278 (6%)

Query  3    EITLLGTGS-PIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGTG  P P  +R+ P+ ++     +++VDCG GV ++  + G+    +  V +TH
Sbjct  44   RLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVSAGLKLKAIRHVFITH  103

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+      P+   GPP  A +    L+ + +DI  RIA    
Sbjct  104  QHSDHNADYGALMLLAWGTDLTG---PVDTWGPPPLAAMTTKFLELYDYDIRTRIADEGR  160

Query  115  LTTPPPIEVHEYTAGPAWDRD-GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P +  HE T G    +D  V +  A   H PV+P   +R ++   S+V++GDT P 
Sbjct  161  PPLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPS  220

Query  174  DSLDQLAAGADALVHTVIRKDIVTQI--PQQRVKDICDY----HSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+    + Q+   ++  K + ++    H+  +E    A  A V 
Sbjct  221  ENLVRLAHGADVLVHEVMHLPSLDQLLSTERNAKTLREHLLASHTPAEEVGRIATEAKVK  280

Query  228  TLVMTHYVPAIGPGQEEQ-WRALAATEFSGRIEVGNDL  264
            TLV++H+VP   P  ++  W       F G I VG DL
Sbjct  281  TLVLSHFVPGGYPNLDDSVWLDAVRPHFKGEIIVGRDL  318


>gi|117618007|ref|YP_855738.1| ribonuclease Z, putative [Aeromonas hydrophila subsp. hydrophila 
ATCC 7966]
 gi|117559414|gb|ABK36362.1| ribonuclease Z, putative [Aeromonas hydrophila subsp. hydrophila 
ATCC 7966]
Length=346

 Score =  127 bits (319),  Expect = 2e-27, Method: Compositional matrix adjust.
 Identities = 88/281 (32%), Positives = 133/281 (48%), Gaps = 16/281 (5%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            +  ++LLGTG+P+P   R G STLV AG Q  + D GR    R   + +    ++A  LT
Sbjct  48   IFRVSLLGTGTPVPQISRGGYSTLVEAGNQKLVFDFGRNSATRLWQLHIPIGRVNAFFLT  107

Query  61   HLHG-------DVLITSWVT-NFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHH  112
            H H        D+ +T W+   +    AP+ + GP GT  +     +A+  DI  R+   
Sbjct  108  HFHSDHTNGLADLWLTGWLQPAYGQRHAPMELYGPRGTDALAHGLQQAYATDIATRVKDE  167

Query  113  ADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHR-PVTPTIGFRIESDGASVVLAGDTV  171
                    I  HE TAG  +D+DGV +     DH   + P+ G+RI+  G SVVL+GDT 
Sbjct  168  GTPLDGVKINSHEVTAGVVYDQDGVKVTAFDNDHGVNIKPSFGYRIDYHGHSVVLSGDTR  227

Query  172  PCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVM  231
                + + A GAD LVH V              + I  + +S ++AA   N A     V 
Sbjct  228  YSPQVVKEAKGADLLVHCVSMTSAARMKANPGYRAIAGHLASPEQAARVLNEAKPALTVF  287

Query  232  THYVPAIGPGQEEQWRALAAT---EFSGRIEVGNDLHRVEV  269
            +H    IG   +   + LA +    +SG   +GNDL ++++
Sbjct  288  SH----IGLNGKITVKDLAQSLRARYSGPFVIGNDLMQIDL  324


>gi|206590350|emb|CAQ37311.1| arylsulfatase precursor (aryl-sulfate sulphohydrolase) protein 
[Ralstonia solanacearum MolK2]
Length=321

 Score =  127 bits (319),  Expect = 2e-27, Method: Compositional matrix adjust.
 Identities = 85/278 (31%), Positives = 138/278 (50%), Gaps = 19/278 (6%)

Query  3    EITLLGTGS-PIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGTG  P P  +R+ P+ ++     +++VDCG GV ++  + G+    +  V +TH
Sbjct  44   RLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVSAGLKLKAIRHVFITH  103

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+      P+   GPP  A +    L+ + +DI  RIA    
Sbjct  104  QHSDHNADYGALMLLAWGTDLTG---PVDTWGPPPLAAMTTKFLELYDYDIRTRIADEGR  160

Query  115  LTTPPPIEVHEYTAGPAWDRD-GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P +  HE T G    +D  V +  A   H PV+P   +R ++   S+V++GDT P 
Sbjct  161  PPLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPS  220

Query  174  DSLDQLAAGADALVHTVIR-----KDIVTQIPQQRVKD-ICDYHSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+      K + T+   + +++ +   H+  +E    A  A V 
Sbjct  221  ENLVRLAYGADVLVHEVMHLPSLDKLLSTERNAKTLREHLLASHTPAEEVGRIATEAKVK  280

Query  228  TLVMTHYVPAIGPGQEEQ-WRALAATEFSGRIEVGNDL  264
            TLV++H+VP   P  ++  W       F G I VG DL
Sbjct  281  TLVLSHFVPGGYPNLDDSVWLDAVRPHFKGEIIVGRDL  318


>gi|83749087|ref|ZP_00946093.1| Metal-dependent hydrolase [Ralstonia solanacearum UW551]
 gi|207742546|ref|YP_002258938.1| arylsulfatase precursor (aryl-sulfate sulphohydrolase) protein 
[Ralstonia solanacearum IPO1609]
 gi|83724277|gb|EAP71449.1| Metal-dependent hydrolase [Ralstonia solanacearum UW551]
 gi|206593938|emb|CAQ60865.1| arylsulfatase precursor (aryl-sulfate sulphohydrolase) protein 
[Ralstonia solanacearum IPO1609]
Length=321

 Score =  127 bits (319),  Expect = 2e-27, Method: Compositional matrix adjust.
 Identities = 85/278 (31%), Positives = 138/278 (50%), Gaps = 19/278 (6%)

Query  3    EITLLGTGS-PIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGTG  P P  +R+ P+ ++     +++VDCG GV ++  + G+    +  V +TH
Sbjct  44   RLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVSAGLKLKAIRHVFITH  103

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+      P+   GPP  A +    L+ + +DI  RIA    
Sbjct  104  QHSDHNADYGALMLLAWGTDLTG---PVDTWGPPPLAAMTTKFLELYDYDIRTRIADEGR  160

Query  115  LTTPPPIEVHEYTAGPAWDRD-GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P +  HE T G    +D  V +  A   H PV+P   +R ++   S+V++GDT P 
Sbjct  161  PPLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPS  220

Query  174  DSLDQLAAGADALVHTVIR-----KDIVTQIPQQRVKD-ICDYHSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+      K + T+   + +++ +   H+  +E    A  A V 
Sbjct  221  ENLVRLAYGADVLVHEVMHLPSLDKLLSTERNAKTLREHLLASHTPAEEVGRIATEAKVK  280

Query  228  TLVMTHYVPAIGPGQEEQ-WRALAATEFSGRIEVGNDL  264
            TLV++H+VP   P  ++  W       F G I VG DL
Sbjct  281  TLVLSHFVPGGYPNLDDSVWLDAVRPHFKGEIIVGRDL  318


>gi|300703243|ref|YP_003744845.1| arylsulfatase [Ralstonia solanacearum CFBP2957]
 gi|299070906|emb|CBJ42208.1| putative arylsulfatase (Aryl-sulfate sulphohydrolase) [Ralstonia 
solanacearum CFBP2957]
Length=321

 Score =  127 bits (318),  Expect = 2e-27, Method: Compositional matrix adjust.
 Identities = 85/278 (31%), Positives = 138/278 (50%), Gaps = 19/278 (6%)

Query  3    EITLLGTGS-PIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGTG  P P  +R+ P+ ++     +++VDCG GV ++  + G+    +  V +TH
Sbjct  44   RLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVSAGLKLKAIRHVFITH  103

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+      P+   GPP  A +    L+ + +DI  RIA    
Sbjct  104  QHSDHNADYGALMLLAWGTDLTG---PVDTWGPPPLAAMTTKFLELYDYDIRTRIADEGR  160

Query  115  LTTPPPIEVHEYT-AGPAWDRDGVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P +  HE T AG       V +  A  +H PV+P   +R ++   S+V++GDT P 
Sbjct  161  PPLAPMLHPHELTEAGLVMQDANVKVTSALVEHPPVSPAFAYRFDAADRSIVISGDTAPS  220

Query  174  DSLDQLAAGADALVHTVIRKDIVTQI--PQQRVKDICDY----HSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+    + Q+   ++  K + ++    H+  +E    A  A V 
Sbjct  221  ENLVRLAYGADVLVHEVMHLPSLDQLLSTERNAKTLREHLLASHTPAEEVGRIATEAKVK  280

Query  228  TLVMTHYVPAIGPGQEE-QWRALAATEFSGRIEVGNDL  264
            TLV++H+VP   P  ++  W       F G I VG DL
Sbjct  281  TLVLSHFVPGGYPYLDDAAWLDAVRPHFKGEIIVGRDL  318


>gi|17547214|ref|NP_520616.1| hydrolase [Ralstonia solanacearum GMI1000]
 gi|17429516|emb|CAD16202.1| probable arylsulfatase precursor (aryl-sulfate sulphohydrolase) 
protein [Ralstonia solanacearum GMI1000]
Length=320

 Score =  125 bits (315),  Expect = 5e-27, Method: Compositional matrix adjust.
 Identities = 86/278 (31%), Positives = 140/278 (51%), Gaps = 19/278 (6%)

Query  3    EITLLGTGS-PIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGTG  P P  +R+ P+ ++     +++VDCG GV ++  + G+    +  V +TH
Sbjct  43   RLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVSAGLTLKAIRHVFITH  102

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+ A    P+   GPP  A +    L+ + +DI  RIA    
Sbjct  103  QHSDHNADYGALMLLAWGTDLAG---PVDAWGPPPLAAMTARFLELYDYDIRTRIADEGR  159

Query  115  LTTPPPIEVHEYTAGPAWDRD-GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P +  HE T G    +D  V +  A   H PV+P   +R ++   S+V++GDT P 
Sbjct  160  PPLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPS  219

Query  174  DSLDQLAAGADALVHTVIR-----KDIVTQIPQQRVKD-ICDYHSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+      K + T+   + +++ +   H+S ++    A  A V 
Sbjct  220  ENLVRLAHGADVLVHEVMHLPSLDKLLSTEPNAKTLREHLLASHTSAEDVGRIATEAKVK  279

Query  228  TLVMTHYVPAIGPGQEE-QWRALAATEFSGRIEVGNDL  264
            TLV++H+VP   P  ++  W       F G I VG DL
Sbjct  280  TLVLSHFVPGGYPYLDDAAWLDAVRPHFKGEIIVGRDL  317


>gi|300690635|ref|YP_003751630.1| arylsulfatase (aryl-sulfate sulphohydrolase) [Ralstonia solanacearum 
PSI07]
 gi|299077695|emb|CBJ50331.1| putative arylsulfatase (Aryl-sulfate sulphohydrolase) [Ralstonia 
solanacearum PSI07]
Length=321

 Score =  125 bits (314),  Expect = 6e-27, Method: Compositional matrix adjust.
 Identities = 86/278 (31%), Positives = 139/278 (50%), Gaps = 19/278 (6%)

Query  3    EITLLGTGS-PIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGTG  P P  +R+ P+ ++     +++VDCG GV ++  + G+    +  V +TH
Sbjct  44   RLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVSAGLKLRAIRHVFITH  103

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+ A    P+   GPP  A +    L+ + +DI  RIA    
Sbjct  104  QHSDHNADYGALMLLAWGTDLAG---PVDAWGPPPLAAMTAKFLELYDYDIRTRIADEGR  160

Query  115  LTTPPPIEVHEYTAGPAWDRD-GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P +  HE T G    +D  V +  A   H PV+P   +R ++   S+V++GDT P 
Sbjct  161  PPLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPS  220

Query  174  DSLDQLAAGADALVHTVIR-----KDIVTQIPQQRVKD-ICDYHSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+      K + T+     +++ +   H+S ++    A  A V 
Sbjct  221  ENLVRLAYGADVLVHEVMHLPSLDKLLSTEPNATTLREHLLASHTSTEDVGRIATEAKVK  280

Query  228  TLVMTHYVPAIGPGQEEQ-WRALAATEFSGRIEVGNDL  264
            TLV++H+VP   P  ++  W       F G I VG DL
Sbjct  281  TLVLSHFVPGGYPYLDDAVWLDAVRPHFKGEIIVGRDL  318


>gi|344167403|emb|CCA79626.1| putative arylsulfatase (Aryl-sulfate sulphohydrolase) [blood 
disease bacterium R229]
Length=321

 Score =  125 bits (314),  Expect = 6e-27, Method: Compositional matrix adjust.
 Identities = 86/278 (31%), Positives = 139/278 (50%), Gaps = 19/278 (6%)

Query  3    EITLLGTGS-PIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLTH  61
             + LLGTG  P P  +R+ P+ ++     +++VDCG GV ++  + G+    +  V +TH
Sbjct  44   RLILLGTGGGPTPKKNRSAPAQVIVINGVSYVVDCGNGVARQYVSAGLKLRAIRHVFITH  103

Query  62   LHGD-------VLITSWVTNFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHHAD  114
             H D       +++ +W T+ A    P+   GPP  A +    L+ + +DI  RIA    
Sbjct  104  QHSDHNADYGALMLLAWGTDLAG---PVDAWGPPPLAAMTTKFLELYDYDIRTRIADEGR  160

Query  115  LTTPPPIEVHEYTAGPAWDRD-GVTIRVAPTDHRPVTPTIGFRIESDGASVVLAGDTVPC  173
                P +  HE T G    +D  V +  A   H PV+P   +R ++   S+V++GDT P 
Sbjct  161  PPLAPMLHPHELTEGGLVMQDANVKVTSALVKHPPVSPAFAYRFDAADRSIVISGDTAPS  220

Query  174  DSLDQLAAGADALVHTVIR-----KDIVTQIPQQRVKD-ICDYHSSVQEAAATANRAGVG  227
            ++L +LA GAD LVH V+      K + T+     +++ +   H+S ++    A  A V 
Sbjct  221  ENLVRLAYGADVLVHEVMHLPSLDKLLSTEPNATTLREHLLASHTSTEDVGRIATEAKVK  280

Query  228  TLVMTHYVPAIGPGQEEQ-WRALAATEFSGRIEVGNDL  264
            TLV++H+VP   P  ++  W       F G I VG DL
Sbjct  281  TLVLSHFVPGGYPYLDDAVWLDAVRPHFKGEIIVGRDL  318


>gi|330830709|ref|YP_004393661.1| ribonuclease Z [Aeromonas veronii B565]
 gi|328805845|gb|AEB51044.1| Ribonuclease Z, putative [Aeromonas veronii B565]
Length=340

 Score =  125 bits (313),  Expect = 9e-27, Method: Compositional matrix adjust.
 Identities = 87/281 (31%), Positives = 131/281 (47%), Gaps = 16/281 (5%)

Query  1    MLEITLLGTGSPIPDPDRAGPSTLVRAGAQAFLVDCGRGVLQRAAAVGVGAAGLSAVLLT  60
            +  ++LLGTG+P+P   R G STLV AG Q  + D GR    R   + +    ++A  LT
Sbjct  44   IFRVSLLGTGTPVPQISRGGYSTLVEAGNQKLVFDFGRNSATRLWQLHIPIGRVNAFFLT  103

Query  61   HLHG-------DVLITSWVT-NFAADPAPLPIIGPPGTAEVVEATLKAFGHDIGYRIAHH  112
            H H        D+ +T W+   +    AP+ + GP  T  +     +A+  DI  R+   
Sbjct  104  HFHSDHTNGLADLWLTGWLQPAYGQRHAPMELYGPKSTDALASGLQQAYATDIATRVKDE  163

Query  113  ADLTTPPPIEVHEYTAGPAWDRDGVTIRVAPTDHR-PVTPTIGFRIESDGASVVLAGDTV  171
                    I  HE TAG  ++ DGV +     DH   + P+ G+RI+  G SVVL+GDT 
Sbjct  164  GTPLDGVEINSHEVTAGVVYNHDGVKVTAFDNDHGVNIKPSFGYRIDYHGHSVVLSGDTR  223

Query  172  PCDSLDQLAAGADALVHTVIRKDIVTQIPQQRVKDICDYHSSVQEAAATANRAGVGTLVM  231
                + + A GAD LVH V              K I  + +S ++AA   N A     V 
Sbjct  224  YSPEVVKQAKGADLLVHCVSMTSAEQMKANPGYKAIAGHLASPEQAAQVMNEAKPALTVF  283

Query  232  THYVPAIGPGQEEQWRALAA---TEFSGRIEVGNDLHRVEV  269
            +H    IG   + + + LA      +SG   +GNDL ++++
Sbjct  284  SH----IGLNGKIRVKDLAQDLRARYSGPFVIGNDLMQIDL  320



Lambda     K      H
   0.319    0.136    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 426144143792


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40