BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2415c Length=297 Score E Sequences producing significant alignments: (Bits) Value gi|15609552|ref|NP_216931.1| hypothetical protein Rv2415c [Mycob... 569 2e-160 gi|289758544|ref|ZP_06517922.1| conserved hypothetical protein [... 569 2e-160 gi|31793594|ref|NP_856087.1| hypothetical protein Mb2438c [Mycob... 566 1e-159 gi|253798507|ref|YP_003031508.1| hypothetical protein TBMG_01559... 506 2e-141 gi|339295312|gb|AEJ47423.1| hypothetical protein CCDC5079_2233 [... 404 8e-111 gi|15841933|ref|NP_336970.1| hypothetical protein MT2488 [Mycoba... 400 1e-109 gi|254819864|ref|ZP_05224865.1| helix-hairpin-helix repeat-conta... 347 2e-93 gi|240170821|ref|ZP_04749480.1| helix-hairpin-helix repeat-conta... 327 1e-87 gi|118466311|ref|YP_880992.1| competence protein ComEA [Mycobact... 323 2e-86 gi|336458238|gb|EGO37219.1| competence protein ComEA-like protei... 322 6e-86 gi|41408324|ref|NP_961160.1| hypothetical protein MAP2226c [Myco... 318 7e-85 gi|296170527|ref|ZP_06852112.1| competence protein ComEA helix-h... 317 2e-84 gi|333990140|ref|YP_004522754.1| hypothetical protein JDM601_150... 273 2e-71 gi|118471779|ref|YP_888843.1| DNA-binding protein [Mycobacterium... 264 1e-68 gi|183983716|ref|YP_001852007.1| membrane protein ComEA [Mycobac... 255 6e-66 gi|108800486|ref|YP_640683.1| competence protein ComEA helix-hai... 249 5e-64 gi|118618948|ref|YP_907280.1| membrane protein ComEA [Mycobacter... 248 7e-64 gi|120404869|ref|YP_954698.1| helix-hairpin-helix repeat-contain... 234 2e-59 gi|169628716|ref|YP_001702365.1| hypothetical protein MAB_1626 [... 214 1e-53 gi|145223249|ref|YP_001133927.1| helix-hairpin-helix repeat-cont... 199 3e-49 gi|226307258|ref|YP_002767218.1| DNA-binding protein [Rhodococcu... 172 7e-41 gi|262203079|ref|YP_003274287.1| competence protein ComEA helix-... 165 8e-39 gi|229493137|ref|ZP_04386929.1| DNA-binding protein [Rhodococcus... 160 3e-37 gi|326381587|ref|ZP_08203281.1| competence protein ComEA helix-h... 157 2e-36 gi|343926807|ref|ZP_08766300.1| putative DNA-binding protein [Go... 153 4e-35 gi|312140322|ref|YP_004007658.1| competence protein comea [Rhodo... 152 5e-35 gi|325677102|ref|ZP_08156771.1| helix-hairpin-helix repeat-conta... 151 1e-34 gi|54023349|ref|YP_117591.1| putative DNA-binding protein [Nocar... 149 6e-34 gi|134098021|ref|YP_001103682.1| competence protein ComEA helix-... 146 4e-33 gi|111018302|ref|YP_701274.1| hypothetical protein RHA1_ro01292 ... 145 6e-33 gi|333918814|ref|YP_004492395.1| hypothetical protein AS9A_1143 ... 140 2e-31 gi|269127474|ref|YP_003300844.1| competence protein ComEA helix-... 140 3e-31 gi|256375340|ref|YP_003099000.1| competence protein ComEA helix-... 135 9e-30 gi|117927981|ref|YP_872532.1| helix-hairpin-helix DNA-binding mo... 132 7e-29 gi|302528892|ref|ZP_07281234.1| competence protein ComEA helix-h... 131 1e-28 gi|226360428|ref|YP_002778206.1| DNA-binding protein [Rhodococcu... 129 4e-28 gi|331695851|ref|YP_004332090.1| competence protein ComEA helix-... 127 3e-27 gi|311743010|ref|ZP_07716818.1| helix-hairpin-helix repeat-conta... 125 1e-26 gi|257055303|ref|YP_003133135.1| DNA uptake protein [Saccharomon... 124 1e-26 gi|296269125|ref|YP_003651757.1| competence protein ComEA helix-... 123 4e-26 gi|119716118|ref|YP_923083.1| helix-hairpin-helix repeat-contain... 121 1e-25 gi|296393431|ref|YP_003658315.1| soluble ligand binding domain-c... 120 3e-25 gi|269926773|ref|YP_003323396.1| competence protein ComEA helix-... 118 1e-24 gi|336119106|ref|YP_004573880.1| putative competence protein Com... 117 3e-24 gi|323359817|ref|YP_004226213.1| DNA uptake protein [Microbacter... 117 3e-24 gi|227504489|ref|ZP_03934538.1| possible competence protein EA [... 115 6e-24 gi|289771695|ref|ZP_06531073.1| DNA-binding protein [Streptomyce... 115 7e-24 gi|29832034|ref|NP_826668.1| DNA-binding protein [Streptomyces a... 115 7e-24 gi|152967378|ref|YP_001363162.1| competence protein ComEA helix-... 115 8e-24 gi|21221027|ref|NP_626806.1| DNA-binding protein [Streptomyces c... 115 1e-23 >gi|15609552|ref|NP_216931.1| hypothetical protein Rv2415c [Mycobacterium tuberculosis H37Rv] gi|148662249|ref|YP_001283772.1| hypothetical protein MRA_2440 [Mycobacterium tuberculosis H37Ra] gi|148823618|ref|YP_001288372.1| hypothetical protein TBFG_12443 [Mycobacterium tuberculosis F11] 43 more sequence titles Length=297 Score = 569 bits (1466), Expect = 2e-160, Method: Compositional matrix adjust. Identities = 297/297 (100%), Positives = 297/297 (100%), Gaps = 0/297 (0%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD Sbjct 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT Sbjct 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 Query 121 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN 180 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN Sbjct 121 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN 180 Query 181 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLN 240 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLN Sbjct 181 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLN 240 Query 241 TATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 TATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV Sbjct 241 TATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 >gi|289758544|ref|ZP_06517922.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] gi|289714108|gb|EFD78120.1| conserved hypothetical protein [Mycobacterium tuberculosis T85] Length=311 Score = 569 bits (1466), Expect = 2e-160, Method: Compositional matrix adjust. Identities = 297/297 (100%), Positives = 297/297 (100%), Gaps = 0/297 (0%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD Sbjct 15 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 74 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT Sbjct 75 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 134 Query 121 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN 180 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN Sbjct 135 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN 194 Query 181 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLN 240 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLN Sbjct 195 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLN 254 Query 241 TATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 TATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV Sbjct 255 TATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 311 >gi|31793594|ref|NP_856087.1| hypothetical protein Mb2438c [Mycobacterium bovis AF2122/97] gi|121638296|ref|YP_978520.1| hypothetical protein BCG_2431c [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224990790|ref|YP_002645477.1| hypothetical protein JTY_2425 [Mycobacterium bovis BCG str. Tokyo 172] 20 more sequence titles Length=297 Score = 566 bits (1459), Expect = 1e-159, Method: Compositional matrix adjust. Identities = 296/297 (99%), Positives = 296/297 (99%), Gaps = 0/297 (0%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD Sbjct 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT Sbjct 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 Query 121 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN 180 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN Sbjct 121 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN 180 Query 181 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLN 240 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLN Sbjct 181 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLN 240 Query 241 TATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 TATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDK RNLVRV Sbjct 241 TATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKLRNLVRV 297 >gi|253798507|ref|YP_003031508.1| hypothetical protein TBMG_01559 [Mycobacterium tuberculosis KZN 1435] gi|289553795|ref|ZP_06443005.1| conserved hypothetical protein [Mycobacterium tuberculosis KZN 605] gi|297635019|ref|ZP_06952799.1| hypothetical protein MtubK4_12899 [Mycobacterium tuberculosis KZN 4207] 6 more sequence titles Length=298 Score = 506 bits (1302), Expect = 2e-141, Method: Compositional matrix adjust. Identities = 297/298 (99%), Positives = 297/298 (99%), Gaps = 1/298 (0%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD Sbjct 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT Sbjct 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 Query 121 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN 180 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN Sbjct 121 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN 180 Query 181 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAE-VLDL 239 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAE VLDL Sbjct 181 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVVLDL 240 Query 240 NTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 NTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV Sbjct 241 NTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 298 >gi|339295312|gb|AEJ47423.1| hypothetical protein CCDC5079_2233 [Mycobacterium tuberculosis CCDC5079] Length=215 Score = 404 bits (1039), Expect = 8e-111, Method: Compositional matrix adjust. Identities = 214/215 (99%), Positives = 215/215 (100%), Gaps = 0/215 (0%) Query 83 LAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSV 142 +AVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSV Sbjct 1 MAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSV 60 Query 143 VGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQP 202 VGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQP Sbjct 61 VGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQP 120 Query 203 RVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIV 262 RVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIV Sbjct 121 RVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIV 180 Query 263 AWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 AWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV Sbjct 181 AWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 215 >gi|15841933|ref|NP_336970.1| hypothetical protein MT2488 [Mycobacterium tuberculosis CDC1551] gi|13882204|gb|AAK46784.1| comE operon protein 1, putative [Mycobacterium tuberculosis CDC1551] Length=213 Score = 400 bits (1029), Expect = 1e-109, Method: Compositional matrix adjust. Identities = 212/213 (99%), Positives = 213/213 (100%), Gaps = 0/213 (0%) Query 85 VIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSVVG 144 +IAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSVVG Sbjct 1 MIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSVVG 60 Query 145 LVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRV 204 LVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRV Sbjct 61 LVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRV 120 Query 205 LGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAW 264 LGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAW Sbjct 121 LGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAW 180 Query 265 RQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 RQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV Sbjct 181 RQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 213 >gi|254819864|ref|ZP_05224865.1| helix-hairpin-helix repeat-containing competence protein ComEA [Mycobacterium intracellulare ATCC 13950] Length=287 Score = 347 bits (889), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 205/300 (69%), Positives = 228/300 (76%), Gaps = 16/300 (5%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 MRTELPAERLQRRL A PD D+ A + D DD NSLLPRWLPD Sbjct 1 MRTELPAERLQRRLRAEPDADAAAGDSGTTSA----------EDSANDDQNSLLPRWLPD 50 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 S +GW ++RADPGRAGA+ LA++AALAVLVTVFTL+RDR PVMSAKLPPVE V+ Sbjct 51 ASDDRGWVAKVRADPGRAGAIGLAIVAALAVLVTVFTLVRDRPAPVMSAKLPPVEKVATA 110 Query 121 NPRSSASPGS-PDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGL 179 +PRSSASP + PD PVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAV+GADT+GL Sbjct 111 SPRSSASPAAEPDH---PVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVNGADTIGL 167 Query 180 NMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTP--GPAGTSGTATTGPKTAPKTAEVL 237 NMAR LGDGEQIVVGLAP GQP LGSSV +G+P A PK E + Sbjct 168 NMARPLGDGEQIVVGLAPAPGQPTALGSSVASGSPPTSKAPPPRPGAGPGSAKPKAGEAV 227 Query 238 DLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 +LNTATV++LDALPG+GPVTAAAIVAWRQ NGRFTSVDQLADV+GIGPARL+K R LVRV Sbjct 228 NLNTATVQELDALPGVGPVTAAAIVAWRQANGRFTSVDQLADVEGIGPARLEKLRALVRV 287 >gi|240170821|ref|ZP_04749480.1| helix-hairpin-helix repeat-containing competence protein ComEA [Mycobacterium kansasii ATCC 12478] Length=304 Score = 327 bits (838), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 218/301 (73%), Positives = 237/301 (79%), Gaps = 12/301 (3%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 MRTELPAERL RRLGA PD A A ++ E D+GPD DDPNSLLPRWLP Sbjct 12 MRTELPAERLHRRLGADPDCRPAANPAAVEAES---ADEGPD-----DDPNSLLPRWLPA 63 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSP- 119 T+ GW ++RADPGRAGA+ALA++AALAVLVTVFTL+RDR PVMSAKLP VE VS Sbjct 64 TTGSHGWLAKVRADPGRAGAIALALVAALAVLVTVFTLLRDRPAPVMSAKLPAVERVSGP 123 Query 120 --TNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTV 177 + PR SA+PG P PVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADT+ Sbjct 124 SGSGPRPSATPGQPPGPDRPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTI 183 Query 178 GLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPA-GTSGTATTGPKTAPKTAEV 236 LNMARQL DGEQIVVGLAP GQP L SS+GAGTP P TSG G + + K AEV Sbjct 184 ALNMARQLVDGEQIVVGLAPVPGQPITLRSSIGAGTPAPGPATSGAPHPGTQPSSKPAEV 243 Query 237 LDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVR 296 LDLNTATVEQLD LPG+GPVTAAAIVAWRQ NGRFTSVDQLADVDGIGPARL+K R+LVR Sbjct 244 LDLNTATVEQLDTLPGVGPVTAAAIVAWRQANGRFTSVDQLADVDGIGPARLEKLRSLVR 303 Query 297 V 297 V Sbjct 304 V 304 >gi|118466311|ref|YP_880992.1| competence protein ComEA [Mycobacterium avium 104] gi|254774583|ref|ZP_05216099.1| helix-hairpin-helix repeat-containing competence protein ComEA [Mycobacterium avium subsp. avium ATCC 25291] gi|118167598|gb|ABK68495.1| competence protein ComEA helix-hairpin-helix repeat region [Mycobacterium avium 104] Length=286 Score = 323 bits (829), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 208/298 (70%), Positives = 227/298 (77%), Gaps = 13/298 (4%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 MRTELPAERLQRRL A PD D A + PE P D P DD NSLLPRWLP Sbjct 1 MRTELPAERLQRRLRAEPDAD-----AAVQPEEPGPI---AGEDFPDDDQNSLLPRWLPG 52 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVS-P 119 +GW RIRADPGRAGA+ LA++AALAVLVTVFTLIRDR PVMSAKLPPVE VS Sbjct 53 APEHRGWVARIRADPGRAGAIGLAIVAALAVLVTVFTLIRDRPAPVMSAKLPPVEKVSTA 112 Query 120 TNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGL 179 + S++ G PDR PVVVSVVGLVHTPGLVTLAPGARIADA+QAAGGAV+GADT GL Sbjct 113 SPRSSASPSGGPDR---PVVVSVVGLVHTPGLVTLAPGARIADAVQAAGGAVNGADTAGL 169 Query 180 NMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDL 239 NMAR L DGEQIVVGLAP GQP VLGSSV AG+ A K PKT++ +DL Sbjct 170 NMARPLDDGEQIVVGLAPVPGQPPVLGSSVAAGSTP-APKPPPGPGAAKAKPKTSDAVDL 228 Query 240 NTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 NTATV++LDALPG+GPVTAAAIVAWRQ NGRFTSVDQLADV+GIGPARL+K R LVRV Sbjct 229 NTATVQELDALPGVGPVTAAAIVAWRQTNGRFTSVDQLADVEGIGPARLEKLRALVRV 286 >gi|336458238|gb|EGO37219.1| competence protein ComEA-like protein with helix-hairpin-helix repeat region [Mycobacterium avium subsp. paratuberculosis S397] Length=286 Score = 322 bits (824), Expect = 6e-86, Method: Compositional matrix adjust. Identities = 207/298 (70%), Positives = 226/298 (76%), Gaps = 13/298 (4%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 M+TELPAERLQRRL A PD D A + PE P D P DD NSLLPRWLP Sbjct 1 MQTELPAERLQRRLRAEPDAD-----AAVQPEEPGPI---AGEDSPDDDQNSLLPRWLPG 52 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVS-P 119 +GW RIRADPGRAGA+ LA++AALAVLVTVFTLIRDR PVMSAKLPPVE VS Sbjct 53 APEHRGWVARIRADPGRAGAIGLAIVAALAVLVTVFTLIRDRPAPVMSAKLPPVEKVSTA 112 Query 120 TNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGL 179 + S++ G PDR PVVVSVVGLVHTPGLVTLAPGARIADA+QAAGGAV+GADT GL Sbjct 113 SPRSSASPSGGPDR---PVVVSVVGLVHTPGLVTLAPGARIADAVQAAGGAVNGADTAGL 169 Query 180 NMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDL 239 NMAR L DGEQIVVGLAP GQP VLGSSV AG+ A K PKT + +DL Sbjct 170 NMARPLDDGEQIVVGLAPVPGQPPVLGSSVAAGSTP-APKPPPGPGAAKAKPKTGDAVDL 228 Query 240 NTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 NTATV++LDALPG+GPVTAAAIVAWRQ NGRFTSVDQLADV+GIGPARL+K R LVRV Sbjct 229 NTATVQELDALPGVGPVTAAAIVAWRQTNGRFTSVDQLADVEGIGPARLEKLRALVRV 286 >gi|41408324|ref|NP_961160.1| hypothetical protein MAP2226c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396680|gb|AAS04543.1| hypothetical protein MAP_2226c [Mycobacterium avium subsp. paratuberculosis K-10] Length=286 Score = 318 bits (815), Expect = 7e-85, Method: Compositional matrix adjust. Identities = 206/298 (70%), Positives = 225/298 (76%), Gaps = 13/298 (4%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 M+TELPAER QRRL A PD D A + PE P D P DD NSLLPRWLP Sbjct 1 MQTELPAERPQRRLRAEPDAD-----AAVQPEEPGPI---AGEDSPDDDQNSLLPRWLPG 52 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVS-P 119 +GW RIRADPGRAGA+ LA++AALAVLVTVFTLIRDR PVMSAKLPPVE VS Sbjct 53 APEHRGWVARIRADPGRAGAIGLAIVAALAVLVTVFTLIRDRPAPVMSAKLPPVEKVSTA 112 Query 120 TNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGL 179 + S++ G PDR PVVVSVVGLVHTPGLVTLAPGARIADA+QAAGGAV+GADT GL Sbjct 113 SPRSSASPSGGPDR---PVVVSVVGLVHTPGLVTLAPGARIADAVQAAGGAVNGADTAGL 169 Query 180 NMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDL 239 NMAR L DGEQIVVGLAP GQP VLGSSV AG+ A K PKT + +DL Sbjct 170 NMARPLDDGEQIVVGLAPVPGQPPVLGSSVAAGSTP-APKPPPGPGAAKAKPKTGDAVDL 228 Query 240 NTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 NTATV++LDALPG+GPVTAAAIVAWRQ NGRFTSVDQLADV+GIGPARL+K R LVRV Sbjct 229 NTATVQELDALPGVGPVTAAAIVAWRQTNGRFTSVDQLADVEGIGPARLEKLRALVRV 286 >gi|296170527|ref|ZP_06852112.1| competence protein ComEA helix-hairpin-helix region [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894819|gb|EFG74543.1| competence protein ComEA helix-hairpin-helix region [Mycobacterium parascrofulaceum ATCC BAA-614] Length=281 Score = 317 bits (812), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 198/298 (67%), Positives = 222/298 (75%), Gaps = 18/298 (6%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 M+ ELP RLQRRLGA PD+D P+ P DE D NSLLPRWLPD Sbjct 1 MQPELPGARLQRRLGAEPDVD---------PDGAGPASSAEAADE---DQNSLLPRWLPD 48 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 S +GWA R+RADPGRAGA+ LA++AALAV+VTVFT++RDR PVMSAKLPPVE S Sbjct 49 GSPDRGWAARLRADPGRAGAIGLAIVAALAVMVTVFTVLRDRPAPVMSAKLPPVERASTV 108 Query 121 NPRSSASPGS-PDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGL 179 + +ASP + PDR PVVVSVVGLVH+PGLVTLA GAR+ADALQAAGGAV+GADTVGL Sbjct 109 SATPTASPAAGPDR---PVVVSVVGLVHSPGLVTLAAGARVADALQAAGGAVNGADTVGL 165 Query 180 NMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDL 239 NMAR LGDGEQIVVGLAP GQP LGSSV G+ + G PK VLDL Sbjct 166 NMARPLGDGEQIVVGLAPVPGQPPALGSSVATGS--TPKPAPPRPGGGPVKPKAGAVLDL 223 Query 240 NTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 NTATV+ LDALPG+GPVTAAAIVAWRQ NG+FTSVDQLA+VDGIGPARL+K R LVRV Sbjct 224 NTATVQDLDALPGVGPVTAAAIVAWRQANGKFTSVDQLAEVDGIGPARLEKLRALVRV 281 >gi|333990140|ref|YP_004522754.1| hypothetical protein JDM601_1500 [Mycobacterium sp. JDM601] gi|333486108|gb|AEF35500.1| membrane protein ComEA [Mycobacterium sp. JDM601] Length=283 Score = 273 bits (698), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 185/300 (62%), Positives = 216/300 (72%), Gaps = 20/300 (6%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 M E P ERLQRRLG +P+ D +A EP D DPNSLLPRWLPD Sbjct 1 MAPEPPGERLQRRLGLLPEPDRTEKAA----EPGD-----------EADPNSLLPRWLPD 45 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 + GW ++RADPGRAGA+ALAVIAA+AVL+TVFT++RDR PV+SAKLPPVE VS Sbjct 46 ATDA-GWLAKVRADPGRAGAIALAVIAAVAVLITVFTVVRDRPAPVLSAKLPPVEMVSTA 104 Query 121 NPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLN 180 + R + P VVVSVVGLVH PGL TL+PG+RIADAL AAGGA+DGADT+GLN Sbjct 105 STRGAEPSADPAPVADQVVVSVVGLVHKPGLATLSPGSRIADALTAAGGALDGADTIGLN 164 Query 181 MARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTP---GPAGTSGTATTGPKTAPKTAEVL 237 +AR + DGEQIVVGL PP+G P VLGSSVGA +P P ++ T K PK E + Sbjct 165 LARPVVDGEQIVVGLVPPAGPP-VLGSSVGAASPPPEAPRSSTAPTATATKPEPKGGEPV 223 Query 238 DLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 +LNTATVEQLDALPG+GPVTAAAIVAWR+ +G+F VDQL DVDGIGPARL+K R LVRV Sbjct 224 NLNTATVEQLDALPGVGPVTAAAIVAWREAHGKFADVDQLGDVDGIGPARLEKLRALVRV 283 >gi|118471779|ref|YP_888843.1| DNA-binding protein [Mycobacterium smegmatis str. MC2 155] gi|118173066|gb|ABK73962.1| DNA-binding protein [Mycobacterium smegmatis str. MC2 155] Length=292 Score = 264 bits (674), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 171/300 (57%), Positives = 204/300 (68%), Gaps = 23/300 (7%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 M TELP +RL+RRLG+ D + A + D E P++ L +WLPD Sbjct 13 MGTELPVQRLRRRLGSDTDATTDTIDAADAGDTED--------SESGVAPDTALSKWLPD 64 Query 61 TSRGQ--GWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVS 118 T+ GQ W + IRADPGR G +ALA + LAVL+TVF ++RDR PVMSA LPPV+ VS Sbjct 65 TTEGQRPAWLNVIRADPGRVGVLALATLGVLAVLITVFVVLRDRPAPVMSANLPPVQMVS 124 Query 119 PTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVG 178 + P A+ G PVVVSVVGLVH PGLVTL+ GARIADAL AAGGA+DGAD +G Sbjct 125 SSAPTPEAAAG-------PVVVSVVGLVHKPGLVTLSSGARIADALTAAGGALDGADLIG 177 Query 179 LNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEV-L 237 LNMAR++ DGEQIVVG+A P+GQP +GSSV A +G A +TA L Sbjct 178 LNMARRVADGEQIVVGIAAPAGQPTTMGSSVST-----AEATGAAEPAAGGGGQTASGPL 232 Query 238 DLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 DLNTATVEQLDALPG+GPVTA AIV+WR NG+F SVDQL +VDGIGPARL+K R LVRV Sbjct 233 DLNTATVEQLDALPGVGPVTAEAIVSWRNANGQFASVDQLGEVDGIGPARLEKLRGLVRV 292 >gi|183983716|ref|YP_001852007.1| membrane protein ComEA [Mycobacterium marinum M] gi|183177042|gb|ACC42152.1| conserved hypothetical membrane protein ComEA [Mycobacterium marinum M] Length=291 Score = 255 bits (651), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 205/303 (68%), Positives = 229/303 (76%), Gaps = 18/303 (5%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 MRTELPAERLQRRL PD+ HA S + HD+ DDPNSLLPRWLP+ Sbjct 1 MRTELPAERLQRRLSTAPDLRLHAESGAAE-------SGADPHDDRDDDPNSLLPRWLPE 53 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 G G R+RADPGRAGA+ALAV+AALAVLVT FTL+RDR PVMSAKLP VE VS + Sbjct 54 AGDGSGLLSRVRADPGRAGAIALAVVAALAVLVTAFTLLRDRPAPVMSAKLPAVEHVSGS 113 Query 121 NPRSSASPGSP------DRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGA 174 + S S SP DR PVVVSVVGLVHTPGL TLAPGAR+ADALQAAGGA+ GA Sbjct 114 SGASPGSSASPAAAAGPDR---PVVVSVVGLVHTPGLFTLAPGARVADALQAAGGALAGA 170 Query 175 DTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTA 234 DT+GLNMARQL DGEQIVVGLAP +GQP+ GSS+GA TP PA + + T P P A Sbjct 171 DTIGLNMARQLADGEQIVVGLAPVAGQPKRFGSSIGAATPSPAPAATSGTRSP--GPNPA 228 Query 235 EVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNL 294 EVLDLNTATVEQLD+LPG+GPVTAAAIV+WR NG+FTSVDQLA+VDGIGPARL K R+L Sbjct 229 EVLDLNTATVEQLDSLPGVGPVTAAAIVSWRAANGKFTSVDQLAEVDGIGPARLQKLRSL 288 Query 295 VRV 297 VRV Sbjct 289 VRV 291 >gi|108800486|ref|YP_640683.1| competence protein ComEA helix-hairpin-helix region [Mycobacterium sp. MCS] gi|119869625|ref|YP_939577.1| helix-hairpin-helix repeat-containing competence protein ComEA [Mycobacterium sp. KMS] gi|126436102|ref|YP_001071793.1| helix-hairpin-helix repeat-containing competence protein ComEA [Mycobacterium sp. JLS] gi|108770905|gb|ABG09627.1| Competence protein ComEA helix-hairpin-helix region [Mycobacterium sp. MCS] gi|119695714|gb|ABL92787.1| competence protein ComEA helix-hairpin-helix repeat protein [Mycobacterium sp. KMS] gi|126235902|gb|ABN99302.1| competence protein ComEA helix-hairpin-helix repeat protein [Mycobacterium sp. JLS] Length=267 Score = 249 bits (635), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 174/299 (59%), Positives = 203/299 (68%), Gaps = 34/299 (11%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 MRTE PAERL RRLGA ++ PDHD R P++ L RWLPD Sbjct 1 MRTEEPAERLHRRLGA---------------------EEEPDHDGAR--PDTALSRWLPD 37 Query 61 TSR--GQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVS 118 T+ G GW +RADPGRAG V LAV+ +AVLVTVFT+ RD PV++AKLP VE VS Sbjct 38 TATPTGPGWVAAVRADPGRAGVVGLAVVGVIAVLVTVFTMWRDDPPPVVAAKLPEVEMVS 97 Query 119 PTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVG 178 +P+ + PD+ PVVVSVVGLVH PGLVTL PGARIADAL+AAGGAVDGAD +G Sbjct 98 SASPKPA-----PDQ---PVVVSVVGLVHKPGLVTLEPGARIADALEAAGGAVDGADLIG 149 Query 179 LNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLD 238 LNMAR+L DGEQI+VG+A GQP +GSS A G A + +T E ++ Sbjct 150 LNMARRLTDGEQIIVGIAAGPGQPATMGSSTTAAGDGGAAAPSGSAPAERTG-APGEPVN 208 Query 239 LNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 LNTATVEQLD LPG+GPVTAAAIVAWR +G F+SVDQL DVDGIGPARL K R+LV V Sbjct 209 LNTATVEQLDTLPGVGPVTAAAIVAWRDAHGAFSSVDQLGDVDGIGPARLAKLRDLVHV 267 >gi|118618948|ref|YP_907280.1| membrane protein ComEA [Mycobacterium ulcerans Agy99] gi|118571058|gb|ABL05809.1| conserved hypothetical membrane protein ComEA [Mycobacterium ulcerans Agy99] Length=291 Score = 248 bits (634), Expect = 7e-64, Method: Compositional matrix adjust. Identities = 202/303 (67%), Positives = 225/303 (75%), Gaps = 18/303 (5%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 MRTELPAERLQRRL PD+ HA S + HD+ DDPNSLLPRWL + Sbjct 1 MRTELPAERLQRRLTTAPDLRLHAESGAAE-------SGADPHDDRDDDPNSLLPRWLSE 53 Query 61 TSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPT 120 G G R+RADPGRAGA+ALAV+AALAVLVT FTL+ DR PVMSAKLP VE VS + Sbjct 54 AGDGSGLLSRVRADPGRAGAIALAVVAALAVLVTAFTLLHDRPAPVMSAKLPAVEHVSGS 113 Query 121 NPRSSASPGSP------DRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGA 174 + S S SP DR PVVVSVVGLVHT GL TLAPGAR+ADALQAAGGA+ GA Sbjct 114 SGASPGSSASPAAAAGPDR---PVVVSVVGLVHTSGLFTLAPGARVADALQAAGGALAGA 170 Query 175 DTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTA 234 DT+GLNMARQL DGEQIVVGLAP +GQP+ GSS+GA TP PA + + T P P A Sbjct 171 DTIGLNMARQLADGEQIVVGLAPVAGQPKRFGSSIGAATPSPAPAATSGTRSP--GPNLA 228 Query 235 EVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNL 294 EVLDLNTATVEQLD+LPG+GPVTAAAIV+WR NG FTSVDQLA+VDGIGPARL K R+L Sbjct 229 EVLDLNTATVEQLDSLPGVGPVTAAAIVSWRAANGNFTSVDQLAEVDGIGPARLQKLRSL 288 Query 295 VRV 297 VRV Sbjct 289 VRV 291 >gi|120404869|ref|YP_954698.1| helix-hairpin-helix repeat-containing competence protein ComEA [Mycobacterium vanbaalenii PYR-1] gi|119957687|gb|ABM14692.1| competence protein ComEA helix-hairpin-helix repeat protein [Mycobacterium vanbaalenii PYR-1] Length=269 Score = 234 bits (596), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 175/299 (59%), Positives = 203/299 (68%), Gaps = 32/299 (10%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPD 60 M TELPAERL+RRLGA D HA D G D D P ++ L RWLP Sbjct 1 MSTELPAERLRRRLGA----DGHA-------------DTGDDEDPP----DTTLSRWLPA 39 Query 61 TSRG--QGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVS 118 ++ G R+RADPGRAG VAL VI +AVLVTV +LIRD V+SAKLPPVE VS Sbjct 40 SAPGGPSALMARVRADPGRAGVVALGVIGIVAVLVTVLSLIRDSPPAVVSAKLPPVEMVS 99 Query 119 PTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVG 178 P + + P VVVSVVGLVHTPGLVTLAPGARIADAL AAGGA+DGAD +G Sbjct 100 SPAPGAGPAAPGPAGP---VVVSVVGLVHTPGLVTLAPGARIADALDAAGGALDGADVLG 156 Query 179 LNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLD 238 LNMAR++ DGEQIVVG+ P+GQP +GSS+ + P S P+T + ++D Sbjct 157 LNMARRVADGEQIVVGIGAPAGQPTEMGSSIVSQAAEPGAAS------PQTPAASTGLVD 210 Query 239 LNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 LNTAT EQLD LPG+GPVTAAAI+AWR NGRF+SV+QL DVDGIGPARLDK R LVRV Sbjct 211 LNTATAEQLDTLPGVGPVTAAAILAWRDANGRFSSVEQLGDVDGIGPARLDKLRALVRV 269 >gi|169628716|ref|YP_001702365.1| hypothetical protein MAB_1626 [Mycobacterium abscessus ATCC 19977] gi|169240683|emb|CAM61711.1| Conserved hypothetical protein (competence protein ComEA?) [Mycobacterium abscessus] Length=277 Score = 214 bits (545), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 133/251 (53%), Positives = 164/251 (66%), Gaps = 21/251 (8%) Query 48 DDPNSLLPRWLPDTSRG---QGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTE 104 +P S L RWLPD+ +GW + +R DPGRAG VAL I LAVLVTVFT++R Sbjct 43 SEPESAL-RWLPDSLTAGGTRGWLESVRTDPGRAGVVALGAIGVLAVLVTVFTVMRQ--- 98 Query 105 PVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADAL 164 P PVS P S + +V+SVVGLV PGLVTLA GAR+ADA+ Sbjct 99 --------PPAPVSANLPPVQPVSSSSVSAPSSLVISVVGLVKRPGLVTLATGARVADAV 150 Query 165 QAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTAT 224 AAGGAVDGAD + LNMAR + DG+QIVVGLAP GQP + SS+ A PAG++G+ Sbjct 151 TAAGGAVDGADVITLNMARPVADGDQIVVGLAPVPGQPVGMASSIVAAGQTPAGSTGS-- 208 Query 225 TGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIG 284 P ++LNTAT +LDALPG+GPV AA+IV WR +G+FTS+DQLA+VDGIG Sbjct 209 ----KGPGAPGRVNLNTATESELDALPGVGPVMAASIVRWRSEHGKFTSIDQLAEVDGIG 264 Query 285 PARLDKRRNLV 295 P+RLDK R+ V Sbjct 265 PSRLDKLRDFV 275 >gi|145223249|ref|YP_001133927.1| helix-hairpin-helix repeat-containing competence protein ComEA [Mycobacterium gilvum PYR-GCK] gi|315443709|ref|YP_004076588.1| competence protein ComEA-like protein with helix-hairpin-helix repeat region [Mycobacterium sp. Spyr1] gi|145215735|gb|ABP45139.1| competence protein ComEA helix-hairpin-helix repeat protein [Mycobacterium gilvum PYR-GCK] gi|315262012|gb|ADT98753.1| competence protein ComEA-like protein with helix-hairpin-helix repeat region [Mycobacterium sp. Spyr1] Length=263 Score = 199 bits (507), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 172/299 (58%), Positives = 199/299 (67%), Gaps = 38/299 (12%) Query 1 MRTELPAERLQRRLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLP- 59 M TELPA+RL+RRLG+ PD DD PD + L RWLP Sbjct 1 MSTELPADRLRRRLGSDPDTAE---------------DDAPD---------TSLSRWLPA 36 Query 60 -DTSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVS 118 + S W RIRADPGRAG +AL V+ +AVLVTV TLI D V+SAKLPPV+ S Sbjct 37 DEPSGPSAWLTRIRADPGRAGVIALGVVGVVAVLVTVLTLIGDSPPAVVSAKLPPVDMAS 96 Query 119 PTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVG 178 P + A VVVSVVGLVHTPGLVTL PG+RIADAL AAGGA+DGAD +G Sbjct 97 SAAPGAPAPAEP-------VVVSVVGLVHTPGLVTLPPGSRIADALDAAGGALDGADMLG 149 Query 179 LNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLD 238 LNMAR++ DGEQIVVGL P GQP +GS+V A P G + P+ +P + ++D Sbjct 150 LNMARRVADGEQIVVGLGAPPGQPTRMGSAVVADAGSPGGGA-----MPENSPGSPGLVD 204 Query 239 LNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 LN+ATVEQLD LPG+GPVTAAAIVAWR NGRFTSVDQL DVDGIGPARLDK R+LVRV Sbjct 205 LNSATVEQLDTLPGVGPVTAAAIVAWRDANGRFTSVDQLGDVDGIGPARLDKLRDLVRV 263 >gi|226307258|ref|YP_002767218.1| DNA-binding protein [Rhodococcus erythropolis PR4] gi|226186375|dbj|BAH34479.1| putative DNA-binding protein [Rhodococcus erythropolis PR4] Length=306 Score = 172 bits (435), Expect = 7e-41, Method: Compositional matrix adjust. Identities = 133/325 (41%), Positives = 172/325 (53%), Gaps = 47/325 (14%) Query 1 MRTELPAERLQRRLGAV-------PDIDSHAASAHLDPEPHDPTDDGP------DHDEPR 47 MR ER + RL A+ +D SA + P P + P D DE Sbjct 1 MRISEERERARDRLAAMDGNYRQRQAVDDFEDSASFERSPQ-PFERSPEWLQDFDEDEYE 59 Query 48 DDPNSLLPRWLPDTSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVM 107 P+S LP+ RG W P R+ LA++AALA + +FT+ D P + Sbjct 60 AQPDSSRFDRLPERWRGTRWR------PSRSATWVLAIVAALATAIGLFTVWWD--SPSL 111 Query 108 SAKLPPVEPVSPTNPRSSASPGSPD--RSGLPV-------------VVSVVGLVHTPGLV 152 A P P + T +A + D S PV VVSVVGLV TPGLV Sbjct 112 QAVPPLPSPQNVTEQNVTAQNVTADDGESASPVPTGVVAEQPPEALVVSVVGLVRTPGLV 171 Query 153 TLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAG 212 L G+RIADAL AAGG ++GA+TVGLN+A++L DG+QIVVG A SG V A Sbjct 172 NLHSGSRIADALAAAGGVLEGAETVGLNLAQKLADGDQIVVGAADQSG-------GVSAS 224 Query 213 TPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFT 272 + + T+G A +++LNTAT +LD LPG+GPVTAAAI++WR NG+FT Sbjct 225 S---STTAGGTGPAAAGESGGAGLVNLNTATEAELDDLPGVGPVTAAAIISWRTSNGKFT 281 Query 273 SVDQLADVDGIGPARLDKRRNLVRV 297 ++QL +VDGIGPARL K R LV V Sbjct 282 DIEQLGEVDGIGPARLAKLRVLVSV 306 >gi|262203079|ref|YP_003274287.1| competence protein ComEA helix-hairpin-helix repeat-containing protein [Gordonia bronchialis DSM 43247] gi|262086426|gb|ACY22394.1| competence protein ComEA helix-hairpin-helix repeat protein [Gordonia bronchialis DSM 43247] Length=286 Score = 165 bits (418), Expect = 8e-39, Method: Compositional matrix adjust. Identities = 105/169 (63%), Positives = 124/169 (74%), Gaps = 9/169 (5%) Query 135 GLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVG 194 G +VVSVVGLVH PGLV L PGAR+ADA+ +AGGA GADTV LN+A+ L DG+QI+VG Sbjct 121 GAQLVVSVVGLVHRPGLVRLPPGARVADAIASAGGARRGADTVSLNLAQLLNDGDQILVG 180 Query 195 LAPPSGQPRVLGSSV----GAGTPGPAGTSGTATTGPKTAPKTAEV--LDLNTATVEQLD 248 A P G RVL S+V G+G P PA GT + P AP + ++LNTAT +QLD Sbjct 181 YAGPDG--RVLRSAVVAATGSGAP-PANEPGTTSGAPSAAPSGSSGSRVNLNTATEDQLD 237 Query 249 ALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 ALPG+GPVTA AI+ WR RNGRFTSVDQL +VDGIGPARL K R+LV V Sbjct 238 ALPGVGPVTARAIIDWRTRNGRFTSVDQLGEVDGIGPARLAKLRDLVTV 286 >gi|229493137|ref|ZP_04386929.1| DNA-binding protein [Rhodococcus erythropolis SK121] gi|229319868|gb|EEN85697.1| DNA-binding protein [Rhodococcus erythropolis SK121] Length=293 Score = 160 bits (404), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 128/318 (41%), Positives = 164/318 (52%), Gaps = 46/318 (14%) Query 1 MRTELPAERLQRRLGAV--------PDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNS 52 MR ER + RL A+ D+D S + P D D D+ P+S Sbjct 1 MRISEERERARDRLAAMDGNYRRRHEDVDEFEDSGSFERSPEWLRD--FDEDDYEAQPDS 58 Query 53 LLPRWLPDTSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLP 112 LP+ RG W P R+ LA++A LA + +F + D P M A +P Sbjct 59 SRFDRLPEHWRGTRWR------PSRSATWVLAIVAVLATGIGLFAVWWD--SPSMQA-VP 109 Query 113 PVEPVSPTNPRSSASPGSPDRSGLPVVVSVVG-------------LVHTPGLVTLAPGAR 159 P+ SP N + S PV V+ LV TPGLV L G+R Sbjct 110 PLP--SPQNVTAENVTAGDGESASPVPTGVMAEQPPEAVVVSVVGLVRTPGLVNLHSGSR 167 Query 160 IADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGT 219 IADAL AAGG +DGA+TVGLN+A++L DG+QIVVG A SG + SS AG PA Sbjct 168 IADALAAAGGVLDGAETVGLNLAQKLVDGDQIVVGAADQSGG---VSSSTTAGGTSPA-- 222 Query 220 SGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLAD 279 A +++LNTAT +LD LPG+GPVTAAAI++WR NG+FT ++QL + Sbjct 223 -------AAGESGGAGLVNLNTATEAELDELPGVGPVTAAAIISWRTSNGKFTDIEQLGE 275 Query 280 VDGIGPARLDKRRNLVRV 297 VDGIGPARL K R LV V Sbjct 276 VDGIGPARLAKLRVLVSV 293 >gi|326381587|ref|ZP_08203281.1| competence protein ComEA helix-hairpin-helix repeat-containing protein [Gordonia neofelifaecis NRRL B-59395] gi|326199834|gb|EGD57014.1| competence protein ComEA helix-hairpin-helix repeat-containing protein [Gordonia neofelifaecis NRRL B-59395] Length=319 Score = 157 bits (396), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 112/249 (45%), Positives = 145/249 (59%), Gaps = 18/249 (7%) Query 60 DTSRGQGWADRIRAD---PGRA-------GAVALAVIAALAVLVTVFTLIRDRTEPVMSA 109 D R WAD D P R+ A+ L V+ +A + ++L++ R EP Sbjct 77 DQVRADDWADEEWEDDWDPPRSRFAMLPPAAIGLLVVGLIACAIAGYSLLK-RNEPTA-- 133 Query 110 KLPPVEPVSPTNPRSSASPGSPDRSGLP-VVVSVVGLVHTPGLVTLAPGARIADALQAAG 168 P V S PR+SA P D S P +VVSVVG+VH PGLVTL AR+ADA+ AG Sbjct 134 --PLVAFESSAGPRTSAPPDPSDGSPDPRIVVSVVGMVHRPGLVTLTGSARVADAIARAG 191 Query 169 GAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPK 228 GA DGAD + LNMA+ L DG+QI++G G V + V A G + G Sbjct 192 GARDGADLLSLNMAQLLRDGDQILIGRD--DGAATVHSAVVAAAGGPAPGAPVPSAPGGS 249 Query 229 TAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARL 288 ++DLN+AT +QLDALPG+GPVTA+AI++WR+ +GRF SVDQLA+VDGIGP RL Sbjct 250 VPAVGTGLVDLNSATADQLDALPGVGPVTASAIISWRESHGRFASVDQLAEVDGIGPGRL 309 Query 289 DKRRNLVRV 297 K + LV V Sbjct 310 AKLKPLVTV 318 >gi|343926807|ref|ZP_08766300.1| putative DNA-binding protein [Gordonia alkanivorans NBRC 16433] gi|343763167|dbj|GAA13226.1| putative DNA-binding protein [Gordonia alkanivorans NBRC 16433] Length=250 Score = 153 bits (386), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 104/216 (49%), Positives = 135/216 (63%), Gaps = 7/216 (3%) Query 86 IAALAVLVTVFTLIRDR-TEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSVVG 144 + +A +V F L R T PV+ P S T+ S+ + P + +VVSVVG Sbjct 38 VGVIACVVAGFGLFRGTDTTPVVDFGAPGP---SSTSEVSAPTAAQPSTTPAQLVVSVVG 94 Query 145 LVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRV 204 LV+ PGLV LAPGAR+A+A++ AGGA GAD + LN+A+ L DG+Q++VG A GQ + Sbjct 95 LVNKPGLVRLAPGARVAEAIEQAGGARKGADLLSLNLAQVLRDGDQVLVGYAGGEGQMSM 154 Query 205 LGSSVGAGTPGPAGTSGTATTGPKTAPKTAEV---LDLNTATVEQLDALPGIGPVTAAAI 261 + VGA PA P A AE ++LNTAT +LDALPG+GPVTA AI Sbjct 155 RSAVVGAEGAAPAPGPSAGPGSPPPASSAAEAGGRVNLNTATETELDALPGVGPVTAKAI 214 Query 262 VAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 + WR+RNGRF SV QLA+VDGIGPARL + R+LV V Sbjct 215 LDWRERNGRFMSVGQLAEVDGIGPARLARLRDLVTV 250 >gi|312140322|ref|YP_004007658.1| competence protein comea [Rhodococcus equi 103S] gi|311889661|emb|CBH48978.1| putative competence protein ComEA [Rhodococcus equi 103S] Length=291 Score = 152 bits (385), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 122/296 (42%), Positives = 153/296 (52%), Gaps = 56/296 (18%) Query 24 AASAHLDPEPHDPTD-----------DGPDHDEPRDDPNSLLPRWLPDTSRGQGWADRIR 72 AA +H D D D D P+ DEP S PR R Sbjct 26 AAESHSDGSAFDAADERAPGWLFERGDAPEQDEP----TSFSPR--------------SR 67 Query 73 ADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPD 132 GR GA L + +A V + RDR P A +PP+ V P + + Sbjct 68 LALGRRGAAVLVLAGLIAAGVAGVAVWRDR--PTAQA-VPPLPVVEVREPEAVGD----E 120 Query 133 RSGLP-------------VVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGL 179 +GLP +VVSVVGLV+ GLV L PG+R+ADAL AAGG GAD +GL Sbjct 121 DAGLPAPAVEAEPVGDAQLVVSVVGLVNQAGLVRLPPGSRVADALAAAGGPRPGADVLGL 180 Query 180 NMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDL 239 NMA ++ DG+QI+VG PP G P +GS+ G + K A ++L Sbjct 181 NMAERVDDGDQILVGAMPPDGGPTTVGSA-------RVGPGAAPGSAAGGGGKAAGKVNL 233 Query 240 NTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLV 295 NTA +LDALPG+GPVTAAAIV+WRQ NG+FT V+QL +VDGIGPARL K R+LV Sbjct 234 NTAGEGELDALPGVGPVTAAAIVSWRQSNGKFTDVEQLGEVDGIGPARLAKLRDLV 289 >gi|325677102|ref|ZP_08156771.1| helix-hairpin-helix repeat-containing competence protein ComEA [Rhodococcus equi ATCC 33707] gi|325552087|gb|EGD21780.1| helix-hairpin-helix repeat-containing competence protein ComEA [Rhodococcus equi ATCC 33707] Length=291 Score = 151 bits (381), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 121/293 (42%), Positives = 154/293 (53%), Gaps = 50/293 (17%) Query 24 AASAHLDPEPHDPTDDGP--------DHDEPRDDPNSLLPRWLPDTSRGQGWADRIRADP 75 AA +H D D D+ D E +D+P S PR R Sbjct 26 AAESHSDGSAFDAADERAPGWLFERGDASE-QDEPTSFSPR--------------SRLAL 70 Query 76 GRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSG 135 GR GA L + +A V + RDR P A +PP+ V P + + +G Sbjct 71 GRRGAAVLVLAGLIAAGVAGVAVWRDR--PTAQA-VPPLPVVEVREPEAVGD----EDAG 123 Query 136 LP-------------VVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMA 182 LP +VVSVVGLV+ GLV L PG+R+ADAL AAGG GAD +GLNMA Sbjct 124 LPAPAVEAEPVGDAQLVVSVVGLVNQAGLVRLPPGSRVADALAAAGGPRPGADVLGLNMA 183 Query 183 RQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTA 242 ++ DG+QI+VG PP G P +GS+ G + K A ++LNTA Sbjct 184 ERVDDGDQILVGAMPPDGGPTTVGSA-------RVGPGAAPGSAAGGGGKAAGKVNLNTA 236 Query 243 TVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLV 295 +LDALPG+GPVTAAAIV+WRQ NG+FT V+QL +VDGIGPARL K R+LV Sbjct 237 GEGELDALPGVGPVTAAAIVSWRQSNGKFTDVEQLGEVDGIGPARLAKLRDLV 289 >gi|54023349|ref|YP_117591.1| putative DNA-binding protein [Nocardia farcinica IFM 10152] gi|54014857|dbj|BAD56227.1| putative DNA-binding protein [Nocardia farcinica IFM 10152] Length=532 Score = 149 bits (376), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 132/265 (50%), Positives = 158/265 (60%), Gaps = 26/265 (9%) Query 55 PRWLPDTSRGQGWADRI--------RADPGRAGAVALAVIAALAVLVTVFTLIRDR--TE 104 P WL + + W R+ R DPGR GAV L ++ LAVLVT F L R + T Sbjct 272 PEWLREPQAPEPWTRRLVPERFRGARVDPGRRGAVTLVLVGVLAVLVTAFVLTRAQPVTH 331 Query 105 PV------MSAKLPPVEPVSPTNPRSSASPGS------PDRSGLPVVVSVVGLVHTPGLV 152 PV + PP PVS +A+PGS P +G +VVSVVGLVH GLV Sbjct 332 PVPPLASVRTTTAPPGVPVSGAARTQAAAPGSVPVPETPPATG-ELVVSVVGLVHRGGLV 390 Query 153 TLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAG 212 L GAR+ADAL AAGG DGAD GLN+A+++ DG+QI+VG A P+G LGS+ Sbjct 391 RLPAGARVADALAAAGGPRDGADLTGLNLAQRVQDGDQILVGAAAPTGDGPRLGSAT--- 447 Query 213 TPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFT 272 TT P TA +DLNTAT QLDALPG+GPVTA AI+AWR NGRFT Sbjct 448 ISAGGAGGAAGTTTGAPVPGTAGKIDLNTATEAQLDALPGVGPVTARAILAWRTANGRFT 507 Query 273 SVDQLADVDGIGPARLDKRRNLVRV 297 +VDQLA+VDGIGPARL + R LV V Sbjct 508 AVDQLAEVDGIGPARLARLRELVTV 532 >gi|134098021|ref|YP_001103682.1| competence protein ComEA helix-hairpin-helix region [Saccharopolyspora erythraea NRRL 2338] gi|291007214|ref|ZP_06565187.1| competence protein ComEA helix-hairpin-helix region [Saccharopolyspora erythraea NRRL 2338] gi|133910644|emb|CAM00757.1| competence protein ComEA helix-hairpin-helix region [Saccharopolyspora erythraea NRRL 2338] Length=200 Score = 146 bits (368), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 104/225 (47%), Positives = 128/225 (57%), Gaps = 27/225 (12%) Query 74 DPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDR 133 DPGR+G +A+ +I + FT+ + E S PP+ T P +P Sbjct 2 DPGRSGLLAIVLIGLVVACALTFTVWTAQPE-AESVPPPPLAAPVLTAP-------APTP 53 Query 134 SGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVV 193 L VVSVVGLV PGL+TL G R+ADALQ AGGA+ GAD LN+AR++ DGEQ+ V Sbjct 54 EAL--VVSVVGLVPKPGLITLHTGDRVADALQGAGGALPGADISALNLARKVSDGEQLYV 111 Query 194 GLAPPSGQPRV-LGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPG 252 G+ PP P + GS VG+ GTSG +DLNTAT EQ D LPG Sbjct 112 GVPPP---PELATGSPVGSAR----GTSGNGNDSK---------IDLNTATEEQFDELPG 155 Query 253 IGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 +G VTA IV WR NGRF SV+QL +VDGIG R + R LVRV Sbjct 156 VGEVTAKRIVQWRTENGRFASVEQLREVDGIGDTRFSRLRELVRV 200 >gi|111018302|ref|YP_701274.1| hypothetical protein RHA1_ro01292 [Rhodococcus jostii RHA1] gi|110817832|gb|ABG93116.1| conserved hypothetical protein [Rhodococcus jostii RHA1] Length=287 Score = 145 bits (367), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 104/232 (45%), Positives = 132/232 (57%), Gaps = 14/232 (6%) Query 67 WADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVS---PTNPR 123 W D R DPGR+GA+ L V+ + TV + DR E LP S Sbjct 65 WRD-ARFDPGRSGALVLIVVGIVVATATVLGVRSDRPETQAVPSLPAAGVHSLTPAPVTT 123 Query 124 SSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMAR 183 + A+ + +VVSVVGLV + GLV L PG+R+ADAL AAGG DG DT+GLN+A+ Sbjct 124 APAAAAAAPAPAEEIVVSVVGLVASTGLVRLPPGSRVADALAAAGGVRDGGDTLGLNLAQ 183 Query 184 QLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTAT 243 +L DG+Q++VG A P +G GA P A +++LNTAT Sbjct 184 RLSDGDQVLVGAATTQAPPSAVG---GASAASPGTAG-------AAAVTGGGLVNLNTAT 233 Query 244 VEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLV 295 +LDALPG+GPVTAAAIVAWR NG FT + QL +VDGIGP RL+K R V Sbjct 234 ETELDALPGVGPVTAAAIVAWRTTNGTFTDISQLGEVDGIGPVRLEKLRGQV 285 >gi|333918814|ref|YP_004492395.1| hypothetical protein AS9A_1143 [Amycolicicoccus subflavus DQS3-9A1] gi|333481035|gb|AEF39595.1| hypothetical protein AS9A_1143 [Amycolicicoccus subflavus DQS3-9A1] Length=305 Score = 140 bits (354), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 106/285 (38%), Positives = 144/285 (51%), Gaps = 33/285 (11%) Query 36 PTDDGPDHDEPRDDPNSLLPRWLPDTSRGQGWADRIRADPGRAGAVALAVIAALAVLVTV 95 P D G + D + P + + R W RIR D R GA+AL + L L Sbjct 31 PNDAGLSQQD-NDTDGAAAPWFTEEEQRPAPWRQRIRLDLTRTGAIALVGVGLLGALFAG 89 Query 96 FTLIRDR------------TEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVV---- 139 F ++RD T+ A L ++ P + S S G + S + VV Sbjct 90 FVMLRDSHGSGATVGVVPVTDGTELAALSALDSADPGHGHGS-SQGIEESSHVEVVQSAH 148 Query 140 --VSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAP 197 VSV G V PGLV L+ GAR+ADAL AGGA+ AD + LN+A+ L DG+QIVVG Sbjct 149 VIVSVAGHVQLPGLVELSEGARVADALSRAGGALPQADLITLNLAQPLADGDQIVVGRRD 208 Query 198 PSGQP-----RVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPG 252 +L + V P G G AT P +++LN+AT L +LPG Sbjct 209 GGSDEIPHVSMILRTGVPVMAADPGGAVGHATAAP--------LVNLNSATESDLVSLPG 260 Query 253 IGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 +GPVTA AI+ WR NG+F+S+++L V GIGPA+LD+ R+ V V Sbjct 261 VGPVTAGAIIEWRSTNGQFSSIEELRQVRGIGPAKLDQIRDHVTV 305 >gi|269127474|ref|YP_003300844.1| competence protein ComEA helix-hairpin-helix repeat-containing protein [Thermomonospora curvata DSM 43183] gi|268312432|gb|ACY98806.1| competence protein ComEA helix-hairpin-helix repeat protein [Thermomonospora curvata DSM 43183] Length=271 Score = 140 bits (352), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 101/224 (46%), Positives = 123/224 (55%), Gaps = 23/224 (10%) Query 75 PGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPG-SPDR 133 PG GA ALAV+ ALAVL+ L R P SA P P ASP P Sbjct 70 PGHPGARALAVLGALAVLLACGYLWLSRPRPQPSADAVPA-------PSVVASPVLHPAP 122 Query 134 SGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVV 193 S +VV V G V PG+VTL PGAR+ADA+QAAGG GADT LN+AR+L DGEQ+++ Sbjct 123 SAANLVVHVAGKVRKPGVVTLPPGARVADAIQAAGGLRPGADTGSLNLARRLVDGEQLMI 182 Query 194 GLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGI 253 GL P+ GP+ A ++DLNTAT EQL+ LPG+ Sbjct 183 GLPAPTTA---------------MPPPDAMPAGPQDAGAPGGLIDLNTATAEQLETLPGV 227 Query 254 GPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 GPV A I+ +R RNG F SV+QL +V GIG R + R VRV Sbjct 228 GPVLAQRIIEYRTRNGGFRSVEQLQEVTGIGARRYAELRTRVRV 271 >gi|256375340|ref|YP_003099000.1| competence protein ComEA helix-hairpin-helix repeat-containing protein [Actinosynnema mirum DSM 43827] gi|255919643|gb|ACU35154.1| competence protein ComEA helix-hairpin-helix repeat protein [Actinosynnema mirum DSM 43827] Length=242 Score = 135 bits (339), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 88/185 (48%), Positives = 107/185 (58%), Gaps = 37/185 (20%) Query 113 PVEPVSPTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVD 172 PV PV+ S+A P +VV V G VH PGLVT+ GAR+AD L AGG Sbjct 95 PVLPVAEATSSSAAPP--------VLVVDVAGEVHAPGLVTVEDGARVADVLSRAGGVKP 146 Query 173 GADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPK 232 GA GLN+AR++ DGEQI VG+ P SG GAG P P Sbjct 147 GASLTGLNLARKVTDGEQIAVGVPPASG---------GAGPPAP---------------- 181 Query 233 TAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRR 292 +++NTATVEQLDALPG+GPVTA IV R R GRFTSV QL +V+GIG ++L K Sbjct 182 ----VNINTATVEQLDALPGVGPVTAQRIVDHRARRGRFTSVQQLGEVEGIGGSKLAKLT 237 Query 293 NLVRV 297 +L+RV Sbjct 238 DLIRV 242 >gi|117927981|ref|YP_872532.1| helix-hairpin-helix DNA-binding motif-containing protein [Acidothermus cellulolyticus 11B] gi|117648444|gb|ABK52546.1| helix-hairpin-helix motif protein [Acidothermus cellulolyticus 11B] Length=250 Score = 132 bits (332), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 81/162 (50%), Positives = 105/162 (65%), Gaps = 9/162 (5%) Query 138 VVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAP 197 +VV VVG V PGLVTL PGAR+ DA+ AAGG + G DTV LN+A +L DGEQ+VVG+ Sbjct 96 LVVDVVGRVAHPGLVTLPPGARVFDAVTAAGGVLPGTDTVALNLASRLVDGEQVVVGIPL 155 Query 198 PSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAE--VLDLNTATVEQLDALPGIGP 255 P+ S +G P + TA + AE +++LNTAT ++L+ LPG+GP Sbjct 156 PT-------SGIGGVLPARDAGEPPSEASRPTAGQAAEHGLINLNTATQQELETLPGVGP 208 Query 256 VTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 V A IVAWR R+GRF+SV QL +V GIGPA+ + R VRV Sbjct 209 VLAGNIVAWRNRHGRFSSVAQLQEVPGIGPAKYAQLRTRVRV 250 >gi|302528892|ref|ZP_07281234.1| competence protein ComEA helix-hairpin-helix region [Streptomyces sp. AA4] gi|302437787|gb|EFL09603.1| competence protein ComEA helix-hairpin-helix region [Streptomyces sp. AA4] Length=280 Score = 131 bits (330), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 97/257 (38%), Positives = 135/257 (53%), Gaps = 46/257 (17%) Query 41 PDHDEPRDDPNSLLPRWLPDTSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIR 100 P+H E R L RWLP ++ G+ GR G + + A A ++ I Sbjct 69 PEHTEHR-----LTRRWLPGSTGLPGFL-------GRRGMIFALALLATAAVIAGGLAIF 116 Query 101 DRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARI 160 R+ P ++P P + A ++ +V+SVVG V +PGLVT+ G+R+ Sbjct 117 GRS---------PAAEIAPPLPTARAQVPHASKANENLVISVVGHVRSPGLVTVPSGSRV 167 Query 161 ADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTS 220 ADAL+AAGGA G D LN+AR+L DGEQ+ VG+ P+ Q +GSS A Sbjct 168 ADALRAAGGANPGVDLTTLNLARKLTDGEQLAVGV--PAAQAAPVGSSAAASK------- 218 Query 221 GTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADV 280 +DLN+AT EQLD+LPG+G VTA I WR ++G F+SV+QL DV Sbjct 219 ----------------IDLNSATAEQLDSLPGVGEVTARRITDWRTQHGGFSSVEQLRDV 262 Query 281 DGIGPARLDKRRNLVRV 297 DGIG ++ +K R V V Sbjct 263 DGIGESKFEKLREQVTV 279 >gi|226360428|ref|YP_002778206.1| DNA-binding protein [Rhodococcus opacus B4] gi|226238913|dbj|BAH49261.1| putative DNA-binding protein [Rhodococcus opacus B4] Length=286 Score = 129 bits (325), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 105/231 (46%), Positives = 139/231 (61%), Gaps = 13/231 (5%) Query 67 WADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDR--TEPVMSAKLPPVEPVSPTNPRS 124 W D R DPGR GA+AL V+ + TV + DR T+ V S V +SP + Sbjct 65 WRD-ARFDPGRYGAIALIVVGIVVATATVLAVRSDRPATQAVPSLPAAGVHSLSPAPEPA 123 Query 125 SASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQ 184 + + +VVSVVGLV + GLV L PGAR+ADAL AAGG DG DT+GLN+A++ Sbjct 124 TVAAAPAPALEEEIVVSVVGLVVSAGLVRLPPGARVADALAAAGGVRDGGDTLGLNLAQR 183 Query 185 LGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATV 244 L DG+Q++VG+A P +G + ++G+ P +++LNTAT Sbjct 184 LSDGDQVLVGVATTQPPPSAVGGT----------SAGSPGPAGAATPAAGGLVNLNTATE 233 Query 245 EQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLV 295 +LDALPG+GPVTAAAIVAWR NG+FT + QL +VDGIGP RL+K R V Sbjct 234 TELDALPGVGPVTAAAIVAWRTTNGKFTDISQLGEVDGIGPVRLEKLRAQV 284 >gi|331695851|ref|YP_004332090.1| competence protein ComEA helix-hairpin-helix repeat-containing protein [Pseudonocardia dioxanivorans CB1190] gi|326950540|gb|AEA24237.1| competence protein ComEA helix-hairpin-helix repeat protein [Pseudonocardia dioxanivorans CB1190] Length=261 Score = 127 bits (318), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 104/241 (44%), Positives = 135/241 (57%), Gaps = 21/241 (8%) Query 57 WLPDTSRGQGWADRIRADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEP 116 W+P+ RG R DPGR GA+ALA++ A+A L + +R P Sbjct 41 WVPEGLRGA------RLDPGRPGAIALALVTAVAALAAAIGVWGERPRAEALPAAP-AAG 93 Query 117 VSPTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADT 176 +SP ++ + G PD P+VVSVVG V PGLV +A GAR+ADAL+AAGG + G D Sbjct 94 LSPLVATTAPTEG-PDAG--PIVVSVVGKVARPGLVRVAAGARLADALEAAGGTLPGTDV 150 Query 177 VGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEV 236 LN+AR+L DGEQ+VVG + A G + + G P Sbjct 151 AALNLARRLTDGEQLVVGAPAAT-----------ADALASGGAAAGSDGGAGGVPGAGAR 199 Query 237 LDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVR 296 +DLN+ATV QLD LPG+GPVTA IV WR RNGRF+ VDQL ++DGIG + + R LV Sbjct 200 IDLNSATVAQLDELPGVGPVTAQHIVDWRTRNGRFSRVDQLREIDGIGERKFGRLRELVV 259 Query 297 V 297 V Sbjct 260 V 260 >gi|311743010|ref|ZP_07716818.1| helix-hairpin-helix repeat-containing competence protein ComEA [Aeromicrobium marinum DSM 15272] gi|311313690|gb|EFQ83599.1| helix-hairpin-helix repeat-containing competence protein ComEA [Aeromicrobium marinum DSM 15272] Length=253 Score = 125 bits (313), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 82/174 (48%), Positives = 100/174 (58%), Gaps = 23/174 (13%) Query 124 SSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMAR 183 S + G +G +VV VVG V PG+VTL PG+R+ +AL AAGG V DT LNMAR Sbjct 103 ESTTAGPTAAAGPDLVVDVVGRVARPGIVTLPPGSRVHEALAAAGGVVGDVDTTALNMAR 162 Query 184 QLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTAT 243 L DGEQ++VG + P G + TGP ++LNTAT Sbjct 163 VLSDGEQLLVG--------------IDPVVPVVPGGGPSGATGP---------VNLNTAT 199 Query 244 VEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 LD LPG+GPVTA +I+ WR NGRFTSVD L DV GIG A LD+ R+LV V Sbjct 200 AADLDELPGVGPVTAESILTWRAENGRFTSVDDLLDVSGIGEATLDRLRDLVTV 253 >gi|257055303|ref|YP_003133135.1| DNA uptake protein [Saccharomonospora viridis DSM 43017] gi|256585175|gb|ACU96308.1| DNA uptake protein [Saccharomonospora viridis DSM 43017] Length=352 Score = 124 bits (312), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 76/162 (47%), Positives = 98/162 (61%), Gaps = 21/162 (12%) Query 138 VVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAP 197 +VVSVVG V PGL+T+ PGAR+AD ++ AGGA D + +N+AR++ DGEQI VG+ P Sbjct 209 LVVSVVGTVARPGLITVRPGARVADVIELAGGADSDTDLLTVNLARRVSDGEQIYVGVTP 268 Query 198 PSG--QPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGP 255 P G P V A P TS A +DLNTA + L LPG+G Sbjct 269 PPGAEHPPV------AAVPADPSTS-------------AAKVDLNTADRQLLQTLPGVGE 309 Query 256 VTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 TA+ I+ WR+R+GRFTSV QL +VDGIG R + R+LV V Sbjct 310 ATASRILEWRERHGRFTSVSQLREVDGIGEKRFARLRDLVSV 351 >gi|296269125|ref|YP_003651757.1| competence protein ComEA helix-hairpin-helix repeat-containing protein [Thermobispora bispora DSM 43833] gi|296091912|gb|ADG87864.1| competence protein ComEA helix-hairpin-helix repeat protein [Thermobispora bispora DSM 43833] Length=315 Score = 123 bits (308), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 108/285 (38%), Positives = 139/285 (49%), Gaps = 22/285 (7%) Query 13 RLGAVPDIDSHAASAHLDPEPHDPTDDGPDHDEPRDDPNSLLPRWLPDTSRGQGWADRIR 72 RL + P + S P P + + HDEP P P P R R Sbjct 53 RLRSAPTVPGPPPSFGALPGPGTRSAEPERHDEPVPAPG--WPGARPTGVRAALGRSLPR 110 Query 73 ADPGRAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPD 132 DPG G AL LA L+T + R R ++ +PP PV+ P ++ + GSP Sbjct 111 LDPGSPGLRALIAAGVLAALITAVFVWRSRP---VAEPIPPPVPVASGGPAATEAAGSPT 167 Query 133 RSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIV 192 + L VVV V G V PG++TLA G+R+ADA+ AAGG GAD +N+AR+L DGEQIV Sbjct 168 PTAL-VVVHVTGKVRRPGVLTLAAGSRVADAIDAAGGVRKGADPGPINLARRLVDGEQIV 226 Query 193 VGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPG 252 VG APP G +++LNTAT EQL ALPG Sbjct 227 VGGAPPGAP----------------TPPGALAPPVPGGSPPGPMVNLNTATAEQLTALPG 270 Query 253 IGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 +G V A I+ +R +G F SVDQL DV GIG R + R+ V V Sbjct 271 VGEVLAQRIIEYRTAHGGFQSVDQLKDVPGIGGQRFARLRDKVSV 315 >gi|119716118|ref|YP_923083.1| helix-hairpin-helix repeat-containing competence protein ComEA [Nocardioides sp. JS614] gi|119536779|gb|ABL81396.1| competence protein ComEA helix-hairpin-helix repeat protein [Nocardioides sp. JS614] Length=300 Score = 121 bits (304), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 84/185 (46%), Positives = 105/185 (57%), Gaps = 27/185 (14%) Query 113 PVEPVSPTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVD 172 P+ SP ++ASP + V V V G V PG+V L GAR+ DAL+AAGGA Sbjct 143 PLSDASPVAAEATASPAT-------VTVDVTGKVRRPGIVVLDTGARVVDALEAAGGARR 195 Query 173 GADTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPK 232 G D GLN+AR L DGEQ+VVG +P P P G + T G P Sbjct 196 GVDLSGLNLARVLVDGEQVVVG------EP----------APTPLGAAAVPTPGAPGGP- 238 Query 233 TAEVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRR 292 ++DLNTAT +L+ALP +GPVTA AI+AWR +G FTSVD+L +VDGIG A L + Sbjct 239 ---LVDLNTATQAELEALPEVGPVTAQAILAWRDEHGGFTSVDELLEVDGIGDATLGQLA 295 Query 293 NLVRV 297 V V Sbjct 296 PFVTV 300 >gi|296393431|ref|YP_003658315.1| soluble ligand binding domain-containing protein [Segniliparus rotundus DSM 44985] gi|296180578|gb|ADG97484.1| Soluble ligand binding domain protein [Segniliparus rotundus DSM 44985] Length=263 Score = 120 bits (301), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 99/275 (36%), Positives = 137/275 (50%), Gaps = 26/275 (9%) Query 34 HDPTDDGPDHDEPRDDPNSLLPRWLPDTSRGQGWADRIRADPGRAGAVALAVIAALAVLV 93 HD D+ +D+ ++P RW Q W+ R+ A A AL + LA+ Sbjct 4 HDAFDETDFYDDGFEEPRR--SRW---KHGEQWWSGRV------AAAAALCAVGVLALAF 52 Query 94 TVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVT 153 T+F R+ + LP V P P + P + +VVSVVG V PGL Sbjct 53 TLFDATREGPKAAAYPALPSVVP----PPTQATEPTTAAAQAREIVVSVVGAVRQPGLAR 108 Query 154 LAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAPPSGQ---PRVLGSSVG 210 LAPGAR+ADA++AAGG A+ LN A++L DG+Q+VVG A S P SS Sbjct 109 LAPGARVADAVEAAGGLNPDAEAAELNFAQRLQDGDQVVVGAAVTSVTPVPPAPKASSAP 168 Query 211 AGTPGPAGTSGTATT--------GPKTAPKTAEVLDLNTATVEQLDALPGIGPVTAAAIV 262 P PA T A++ AP ++ D+NTAT +LD +PG+G A AIV Sbjct 169 RPGPVPAATRAPASSRCDCAGGSAGGAAPSRSKQTDVNTATEAELDIVPGVGKSIARAIV 228 Query 263 AWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 +R +GR ++D+LA V +G RL K R +RV Sbjct 229 QYRAAHGRIRNLDELAKVKQVGARRLQKLRPYLRV 263 >gi|269926773|ref|YP_003323396.1| competence protein ComEA helix-hairpin-helix repeat protein [Thermobaculum terrenum ATCC BAA-798] gi|269790433|gb|ACZ42574.1| competence protein ComEA helix-hairpin-helix repeat protein [Thermobaculum terrenum ATCC BAA-798] Length=206 Score = 118 bits (296), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 65/158 (42%), Positives = 98/158 (63%), Gaps = 8/158 (5%) Query 138 VVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAP 197 V V ++G V PG+ TL +R+ D ++ AGG ADT+ +N+A+ L D Q++V Sbjct 54 VTVHILGAVSKPGVYTLPARSRVVDVVKMAGGFTTRADTMSVNLAQILRDEMQVIVPFKA 113 Query 198 PSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVT 257 P + LGS+ G P +SG+A P+ AP +++NTAT EQL+ LPGIGP Sbjct 114 PGSK---LGSNNGQSALNPTHSSGSAAQEPQVAP-----ININTATKEQLEELPGIGPSK 165 Query 258 AAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLV 295 AAAI+ +RQ++G F S++ L DV GIGP+ L+ +++V Sbjct 166 AAAIIEFRQKHGPFNSLEDLLDVPGIGPSTLENIKSMV 203 >gi|336119106|ref|YP_004573880.1| putative competence protein ComEA [Microlunatus phosphovorus NM-1] gi|334686892|dbj|BAK36477.1| putative competence protein ComEA [Microlunatus phosphovorus NM-1] Length=282 Score = 117 bits (292), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 88/223 (40%), Positives = 122/223 (55%), Gaps = 13/223 (5%) Query 77 RAGAVALAVIAALAVLVTVFTLIRDRTEPVMSAKLPPVEPVSPTNPRSSA-SPGSPDRSG 135 R + +A I L +L+ + ++R R PV A PP PT SSA S +P + Sbjct 71 RPHVIIVAAIVVLGILLAGWAVLRAR--PVAVAVTPPT--AGPTASASSAPSDPAPSANT 126 Query 136 LPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGL 195 + V V+G V PG+V LA G+R+ DALQ AGG AD LN+A+ + DG+QIVVG Sbjct 127 AELFVHVLGAVKKPGVVKLATGSRVQDALQKAGGLTGKADPGELNLAQPVSDGQQIVVGT 186 Query 196 A-PPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIG 254 P+G+ R S G+ + S GP+ ++LNTAT QL+ LPG+G Sbjct 187 KGKPNGEVRDGTSGGGSSGTTGSSGSSGGAAGPQP-------VNLNTATQAQLEELPGVG 239 Query 255 PVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 PV A I+AWR NGRF+ V++L ++ G+GP K L RV Sbjct 240 PVMAGKIIAWRTENGRFSRVEELQEISGVGPKTYAKLAPLCRV 282 >gi|323359817|ref|YP_004226213.1| DNA uptake protein [Microbacterium testaceum StLB037] gi|323276188|dbj|BAJ76333.1| DNA uptake protein [Microbacterium testaceum StLB037] Length=205 Score = 117 bits (292), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 95/222 (43%), Positives = 121/222 (55%), Gaps = 34/222 (15%) Query 77 RAGAVALAVIAALAVLVTV-FTLIRDRTEPVMSAKLPPVEPVSPTNPRSSASPGSPDRSG 135 R G A+ V+ LA VT+ ++R + V+ VS + + +P +P +G Sbjct 17 RLGVGAVIVLLVLAFAVTIGIGMLR---------GVSGVQGVSAASSPITTAP-APPAAG 66 Query 136 LPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGL 195 L V V G V PGL LA G R+ADA+ AGG D A+ G+N+AR + DGEQIVV + Sbjct 67 L--CVHVAGAVRAPGLYRLAAGDRVADAIARAGGFTDDAERAGVNLARPVADGEQIVVPV 124 Query 196 APPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGP 255 VGA TP G A+ P TA ++DLNTAT EQLD LP +GP Sbjct 125 -------------VGA-TP-----DGGASVAPGTA--AGGLIDLNTATREQLDTLPRVGP 163 Query 256 VTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVRV 297 A I+AWR+ NGRFTSVD L V GIG LD R+LVRV Sbjct 164 AIADRIIAWRKENGRFTSVDDLGSVPGIGQKMLDGLRDLVRV 205 >gi|227504489|ref|ZP_03934538.1| possible competence protein EA [Corynebacterium striatum ATCC 6940] gi|227198906|gb|EEI78954.1| possible competence protein EA [Corynebacterium striatum ATCC 6940] Length=208 Score = 115 bits (289), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 83/183 (46%), Positives = 105/183 (58%), Gaps = 33/183 (18%) Query 115 EPVSPTNPRSSASPGSPDRSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGA 174 EP + T+P SS +P S L VVSVVG V PGLVT+AP ARIADAL A G Sbjct 59 EPYAATSPTSS----TPAPSSL--VVSVVGEVDNPGLVTVAPDARIADALDHARPK-PGI 111 Query 175 DTVGLNMARQLGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTA 234 D + LN+A++L DGEQIVVG+ P PGPAG G Sbjct 112 DLLNLNLAKRLTDGEQIVVGMPAP--------------VPGPAGEPGQG----------- 146 Query 235 EVLDLNTATVEQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNL 294 +L LN AT EQL L G+G VTA AI+A R+ G F+SV+QL D+ GIGPA+ + ++ Sbjct 147 -LLSLNAATKEQLMDLKGVGEVTAEAIIAHREEIGGFSSVEQLMDISGIGPAKFEGLKDQ 205 Query 295 VRV 297 V++ Sbjct 206 VQL 208 >gi|289771695|ref|ZP_06531073.1| DNA-binding protein [Streptomyces lividans TK24] gi|289701894|gb|EFD69323.1| DNA-binding protein [Streptomyces lividans TK24] Length=348 Score = 115 bits (289), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 92/232 (40%), Positives = 122/232 (53%), Gaps = 28/232 (12%) Query 77 RAGAVALAVIAALAVLVTVFTLIRDRTEPVMS-------AKLPPVEPVSPTNPRSSASPG 129 R AL+V+ +A + V RT PV + A +P R +A Sbjct 132 RRSVAALSVLLVIAAVFAVQHFWTGRTHPVAAPEVVREAAAYGAGKPEPTAEDRDTAGGS 191 Query 130 SPD-----RSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQ 184 P +G +VV V G V PG+ +L G+R+ADAL+AAGG G T GLN AR Sbjct 192 GPKAAATATAGPEIVVDVGGKVRDPGVHSLPAGSRVADALRAAGGVRPGTKTDGLNRARF 251 Query 185 LGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATV 244 L DGEQ++VG P +P GAG P P G +G A GP A + L+TAT Sbjct 252 LVDGEQVIVGAPAPVPRP-------GAG-PAPDGPTGVA--GP------AAPVSLSTATT 295 Query 245 EQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVR 296 +QLD LPG+GPV A I+ +R ++G F SVD+L +V+GIG R R+LVR Sbjct 296 DQLDTLPGVGPVLAQHIIDYRTQHGGFRSVDELREVNGIGERRFADLRDLVR 347 >gi|29832034|ref|NP_826668.1| DNA-binding protein [Streptomyces avermitilis MA-4680] gi|29609152|dbj|BAC73203.1| putative exogenous DNA-binding protein [Streptomyces avermitilis MA-4680] Length=387 Score = 115 bits (289), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 72/159 (46%), Positives = 93/159 (59%), Gaps = 15/159 (9%) Query 138 VVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAP 197 +VV V G V PG+ L G+R+ADAL+AAGG G + GLN AR L DGEQ+VVG Sbjct 243 IVVDVSGKVRNPGIQRLPAGSRVADALRAAGGVRPGTNMQGLNRARLLADGEQVVVGGPA 302 Query 198 PSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVT 257 P+ P GT+ TAT G + + LNTAT +QLD LPG+GPV Sbjct 303 PAPDP---------------GTAATATGGSGAGTTPSTPVSLNTATADQLDTLPGVGPVL 347 Query 258 AAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVR 296 A I+ +R ++G F SVD+L +V+GIG R +NLVR Sbjct 348 AQHIIDYRTQHGGFRSVDELREVNGIGDRRFADLQNLVR 386 >gi|152967378|ref|YP_001363162.1| competence protein ComEA helix-hairpin-helix repeat-containing protein [Kineococcus radiotolerans SRS30216] gi|151361895|gb|ABS04898.1| competence protein ComEA helix-hairpin-helix repeat protein [Kineococcus radiotolerans SRS30216] Length=304 Score = 115 bits (288), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 77/158 (49%), Positives = 95/158 (61%), Gaps = 21/158 (13%) Query 138 VVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQLGDGEQIVVGLAP 197 VVV V G V PGLVTL G+R+ DAL AAGGA+ GAD +N+AR L DGEQ++V + Sbjct 166 VVVHVTGRVTAPGLVTLPAGSRVGDALTAAGGALPGADLDAVNLARVLVDGEQVLVPV-- 223 Query 198 PSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATVEQLDALPGIGPVT 257 P P + ++ GAG+ G GP LDLN AT E+LD LPG+G V Sbjct 224 PGQHPVAVPAAPGAGSRG----------GP---------LDLNAATPEELDGLPGVGEVL 264 Query 258 AAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLV 295 A IVAWR+ NG F V+ L +V GIGP LD R+LV Sbjct 265 AGRIVAWREENGPFRDVEDLGEVPGIGPKVLDGLRDLV 302 >gi|21221027|ref|NP_626806.1| DNA-binding protein [Streptomyces coelicolor A3(2)] gi|6714674|emb|CAB66246.1| putative DNA-binding protein [Streptomyces coelicolor A3(2)] Length=355 Score = 115 bits (287), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 92/232 (40%), Positives = 122/232 (53%), Gaps = 28/232 (12%) Query 77 RAGAVALAVIAALAVLVTVFTLIRDRTEPVMS-------AKLPPVEPVSPTNPRSSASPG 129 R AL+V+ +A + V RT PV + A +P R +A Sbjct 139 RRSVAALSVLLVVAAVFAVQHFWTGRTHPVAAPEVVREAAAYGAGKPEPTAEDRDTAGGS 198 Query 130 SPD-----RSGLPVVVSVVGLVHTPGLVTLAPGARIADALQAAGGAVDGADTVGLNMARQ 184 P +G +VV V G V PG+ +L G+R+ADAL+AAGG G T GLN AR Sbjct 199 GPKAAATATAGPEIVVDVGGKVRDPGVHSLPAGSRVADALRAAGGVRPGTKTDGLNRARF 258 Query 185 LGDGEQIVVGLAPPSGQPRVLGSSVGAGTPGPAGTSGTATTGPKTAPKTAEVLDLNTATV 244 L DGEQ++VG P +P GAG P P G +G A GP A + L+TAT Sbjct 259 LVDGEQVIVGAPAPVPRP-------GAG-PAPDGPTGAA--GP------AAPVSLSTATT 302 Query 245 EQLDALPGIGPVTAAAIVAWRQRNGRFTSVDQLADVDGIGPARLDKRRNLVR 296 +QLD LPG+GPV A I+ +R ++G F SVD+L +V+GIG R R+LVR Sbjct 303 DQLDTLPGVGPVLAQHIIDYRTQHGGFRSVDELREVNGIGERRFADLRDLVR 354 Lambda K H 0.314 0.134 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 495791177136 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40