BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2434c Length=481 Score E Sequences producing significant alignments: (Bits) Value gi|15609571|ref|NP_216950.1| transmembrane protein [Mycobacteriu... 966 0.0 gi|298525914|ref|ZP_07013323.1| conserved hypothetical protein [... 963 0.0 gi|254232569|ref|ZP_04925896.1| hypothetical protein TBCG_02376 ... 931 0.0 gi|289762603|ref|ZP_06521981.1| conserved hypothetical protein [... 919 0.0 gi|254551484|ref|ZP_05141931.1| hypothetical protein Mtube_13659... 808 0.0 gi|240170849|ref|ZP_04749508.1| hypothetical protein MkanA1_1616... 705 0.0 gi|323718941|gb|EGB28091.1| cyclic nucleotide-binding protein [M... 697 0.0 gi|183983736|ref|YP_001852027.1| hypothetical protein MMAR_3756 ... 683 0.0 gi|118618965|ref|YP_907297.1| hypothetical protein MUL_3699 [Myc... 675 0.0 gi|296170505|ref|ZP_06852092.1| cyclic nucleotide-binding protei... 648 0.0 gi|254819844|ref|ZP_05224845.1| hypothetical protein MintA_07964... 625 5e-177 gi|342857829|ref|ZP_08714485.1| hypothetical protein MCOL_03105 ... 623 2e-176 gi|254774562|ref|ZP_05216078.1| hypothetical protein MaviaA2_078... 599 4e-169 gi|240170839|ref|ZP_04749498.1| hypothetical protein MkanA1_1611... 598 8e-169 gi|118466400|ref|YP_882384.1| transmembrane protein [Mycobacteri... 591 9e-167 gi|254775650|ref|ZP_05217166.1| transmembrane protein [Mycobacte... 587 2e-165 gi|254820708|ref|ZP_05225709.1| transmembrane protein [Mycobacte... 583 3e-164 gi|336457929|gb|EGO36920.1| small-conductance mechanosensitive c... 581 8e-164 gi|183983734|ref|YP_001852025.1| hypothetical protein MMAR_3754 ... 575 7e-162 gi|333990120|ref|YP_004522734.1| transmembrane protein [Mycobact... 573 3e-161 gi|342860845|ref|ZP_08717495.1| transmembrane protein [Mycobacte... 572 4e-161 gi|118618963|ref|YP_907295.1| hypothetical protein MUL_3697 [Myc... 568 9e-160 gi|118473923|ref|YP_887882.1| transmembrane protein [Mycobacteri... 543 3e-152 gi|289758566|ref|ZP_06517944.1| cyclic nucleotide-binding protei... 484 1e-134 gi|336458216|gb|EGO37197.1| small-conductance mechanosensitive c... 445 9e-123 gi|41408346|ref|NP_961182.1| hypothetical protein MAP2248c [Myco... 442 8e-122 gi|41407376|ref|NP_960212.1| hypothetical protein MAP1278c [Myco... 389 8e-106 gi|229818727|ref|YP_002880253.1| cyclic nucleotide-regulated sma... 326 5e-87 gi|339295327|gb|AEJ47438.1| transmembrane protein [Mycobacterium... 314 2e-83 gi|289758565|ref|ZP_06517943.1| cyclic nucleotide-binding protei... 259 8e-67 gi|158334573|ref|YP_001515745.1| mechanosensitive ion channel/cy... 235 1e-59 gi|307151658|ref|YP_003887042.1| cyclic nucleotide-regulated sma... 234 3e-59 gi|332709913|ref|ZP_08429869.1| small-conductance mechanosensiti... 233 5e-59 gi|254422992|ref|ZP_05036710.1| transporter, MscS family [Synech... 227 3e-57 gi|126660522|ref|ZP_01731629.1| probable conserved transmembrane... 192 1e-46 gi|220906966|ref|YP_002482277.1| cyclic nucleotide-regulated sma... 169 1e-39 gi|254425845|ref|ZP_05039562.1| transporter, MscS family [Synech... 159 9e-37 gi|41408347|ref|NP_961183.1| hypothetical protein MAP2249c [Myco... 153 6e-35 gi|158425588|ref|YP_001526880.1| integral membrane protein [Azor... 139 9e-31 gi|67925546|ref|ZP_00518878.1| hypothetical protein CwatDRAFT_06... 127 4e-27 gi|300864235|ref|ZP_07109118.1| putative Cyclic nucleotide-regul... 127 5e-27 gi|300866764|ref|ZP_07111446.1| putative Cyclic nucleotide-regul... 123 8e-26 gi|159899231|ref|YP_001545478.1| cyclic nucleotide-regulated sma... 120 6e-25 gi|182678163|ref|YP_001832309.1| cyclic nucleotide-regulated sma... 114 5e-23 gi|196230474|ref|ZP_03129336.1| MscS Mechanosensitive ion channe... 111 3e-22 gi|241205479|ref|YP_002976575.1| cyclic nucleotide-regulated sma... 110 5e-22 gi|115376585|ref|ZP_01463816.1| transporter, small conductance m... 110 5e-22 gi|158423266|ref|YP_001524558.1| mechanosensitive ion channel pr... 109 9e-22 gi|330827988|ref|YP_004390940.1| small conductance mechanosensit... 109 1e-21 gi|222087270|ref|YP_002545805.1| mechanosensitive ion channel pr... 108 3e-21 >gi|15609571|ref|NP_216950.1| transmembrane protein [Mycobacterium tuberculosis H37Rv] gi|15841954|ref|NP_336991.1| cyclic nucleotide-binding protein [Mycobacterium tuberculosis CDC1551] gi|31793614|ref|NP_856107.1| transmembrane protein [Mycobacterium bovis AF2122/97] 66 more sequence titles Length=481 Score = 966 bits (2496), Expect = 0.0, Method: Compositional matrix adjust. Identities = 481/481 (100%), Positives = 481/481 (100%), Gaps = 0/481 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL Sbjct 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF Sbjct 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST Sbjct 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV Sbjct 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI Sbjct 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE Sbjct 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPAR 480 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPAR Sbjct 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPAR 480 Query 481 R 481 R Sbjct 481 R 481 >gi|298525914|ref|ZP_07013323.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298495708|gb|EFI31002.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=481 Score = 963 bits (2489), Expect = 0.0, Method: Compositional matrix adjust. Identities = 480/481 (99%), Positives = 480/481 (99%), Gaps = 0/481 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL Sbjct 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVA F Sbjct 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVALF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST Sbjct 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV Sbjct 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI Sbjct 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE Sbjct 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPAR 480 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPAR Sbjct 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPAR 480 Query 481 R 481 R Sbjct 481 R 481 >gi|254232569|ref|ZP_04925896.1| hypothetical protein TBCG_02376 [Mycobacterium tuberculosis C] gi|124601628|gb|EAY60638.1| hypothetical protein TBCG_02376 [Mycobacterium tuberculosis C] Length=464 Score = 931 bits (2406), Expect = 0.0, Method: Compositional matrix adjust. Identities = 464/464 (100%), Positives = 464/464 (100%), Gaps = 0/464 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL Sbjct 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF Sbjct 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST Sbjct 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV Sbjct 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI Sbjct 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE Sbjct 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRD 464 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRD Sbjct 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRD 464 >gi|289762603|ref|ZP_06521981.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] gi|289710109|gb|EFD74125.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 1503] Length=479 Score = 919 bits (2376), Expect = 0.0, Method: Compositional matrix adjust. Identities = 476/481 (99%), Positives = 477/481 (99%), Gaps = 2/481 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL Sbjct 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LVKASEVPAEDPTVRVLTTAFGFLVL+L L NATLFQGAPQQSWRKRLPAIFVDVARF Sbjct 61 LVKASEVPAEDPTVRVLTTAFGFLVLLLSLL--NATLFQGAPQQSWRKRLPAIFVDVARF 118 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 119 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 178 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST Sbjct 179 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 238 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV Sbjct 239 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 298 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI Sbjct 299 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 358 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE Sbjct 359 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 418 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPAR 480 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPAR Sbjct 419 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPAR 478 Query 481 R 481 R Sbjct 479 R 479 >gi|254551484|ref|ZP_05141931.1| hypothetical protein Mtube_13659 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=480 Score = 808 bits (2088), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/481 (91%), Positives = 442/481 (92%), Gaps = 1/481 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL Sbjct 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF Sbjct 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST Sbjct 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV Sbjct 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI Sbjct 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLK L Sbjct 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKGAAVQALLVALAVRGLGSCWIGS 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPAR 480 + A + R+ L+ V +P+ +G DERQRKAQQAIRRDLHQSPAAAGEHRGPAR Sbjct 421 TIFAADLVRDELDLPVDWEPLGAIAIGYA-DERQRKAQQAIRRDLHQSPAAAGEHRGPAR 479 Query 481 R 481 R Sbjct 480 R 480 >gi|240170849|ref|ZP_04749508.1| hypothetical protein MkanA1_16167 [Mycobacterium kansasii ATCC 12478] Length=467 Score = 705 bits (1819), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/464 (79%), Positives = 407/464 (88%), Gaps = 0/464 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MN+L + WFYWAV IAIGLP GLI+LTELHN LVRR SHLARQ LLRNYLLPLGA+LLL Sbjct 1 MNVLSTPWFYWAVAIAIGLPVGLIILTELHNSLVRRKSHLARQVGLLRNYLLPLGALLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LVKAS++PA D TVR+LTT FGFLVLVLLLS LNAT+FQ AP+ SWRKRLP IF+DVARF Sbjct 61 LVKASQIPAGDGTVRILTTLFGFLVLVLLLSALNATVFQSAPEDSWRKRLPTIFLDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALIG+GLA+ILSY+WGVRVGG+F ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 121 ALIGVGLAMILSYVWGVRVGGIFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+TPTARGRVVEVNWRAVHI+TG+GL+I PNSMLATT+FTNLSRP G+H+C+ITT F+ Sbjct 181 WLDTPTARGRVVEVNWRAVHIETGTGLRITPNSMLATTSFTNLSRPGGSHKCTITTKFAA 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 +D P++VCAML R A LP +KPG +P T+A G EYRTTVRL SPAD+G QATFL WV Sbjct 241 ADAPNQVCAMLTRIAGGLPQLKPGTIPETVALGGGEYRTTVRLRSPADDGAAQATFLPWV 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARRE LHLDE+DDEFST ERV ALRTVVGPELRLS ++QQSL YAR+VRYG DEI Sbjct 301 WYAARREELHLDESDDEFSTTERVWDALRTVVGPELRLSLTEQQSLVPYARVVRYGADEI 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 VQHAGVVP G+ F+IAGSVRLT T +DGSVV I TL +G FLGLTALTRQP+PAGAVALE Sbjct 361 VQHAGVVPKGMAFIIAGSVRLTATAEDGSVVPIGTLNQGAFLGLTALTRQPNPAGAVALE 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRD 464 E+TAL+I REHLE VVMNKPMLLQELGR+IDERQ KAQ+ R+ Sbjct 421 EMTALEIDREHLEHVVMNKPMLLQELGRLIDERQSKAQRVTGRE 464 >gi|323718941|gb|EGB28091.1| cyclic nucleotide-binding protein [Mycobacterium tuberculosis CDC1551A] Length=345 Score = 697 bits (1800), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/345 (99%), Positives = 345/345 (100%), Gaps = 0/345 (0%) Query 137 VRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVVEVNW 196 +RVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVVEVNW Sbjct 1 MRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVVEVNW 60 Query 197 RAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAMLNRAAS 256 RAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAMLNRAAS Sbjct 61 RAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAMLNRAAS 120 Query 257 ALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAARREGLHLDEADD 316 ALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAARREGLHLDEADD Sbjct 121 ALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAARREGLHLDEADD 180 Query 317 EFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIA 376 EFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIA Sbjct 181 EFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIA 240 Query 377 GSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVV 436 GSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVV Sbjct 241 GSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVV 300 Query 437 MNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPARR 481 MNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPARR Sbjct 301 MNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPARR 345 >gi|183983736|ref|YP_001852027.1| hypothetical protein MMAR_3756 [Mycobacterium marinum M] gi|183177062|gb|ACC42172.1| conserved hypothetical membrane protein [Mycobacterium marinum M] Length=466 Score = 683 bits (1762), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/464 (76%), Positives = 402/464 (87%), Gaps = 1/464 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MN+L ++WF+WAVGIAIG+P GLI+LTELHN L RRNSHLARQ +LLRN+LLPLGA+LL Sbjct 1 MNVLGASWFHWAVGIAIGVPVGLILLTELHNSLARRNSHLARQVTLLRNFLLPLGALLLF 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LVKAS+VPA + TVR+LTT FGFLVLVLLLS LNAT+F APQ SWRKRLP IF+DVARF Sbjct 61 LVKASQVPAGEGTVRILTTVFGFLVLVLLLSALNATVFASAPQDSWRKRLPTIFLDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALIGIGLA+ILSY+WGVRVGG+F ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 121 ALIGIGLAMILSYVWGVRVGGIFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+TPTARGRVVEVNWRAVHI+TG+GL+I PNS+LATTAFTNLSRP G+H+CSITT F+ Sbjct 181 WLDTPTARGRVVEVNWRAVHIETGTGLRITPNSVLATTAFTNLSRPGGSHKCSITTKFAA 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 D PDKVCAML R ASALP++K GV+PAT+A G AEYRTTVR+ SPA++G Q TFLRWV Sbjct 241 DDAPDKVCAMLTRVASALPNLKSGVMPATVALGGAEYRTTVRIKSPAEDGAAQDTFLRWV 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARREGL LD A D FST +RV+ ALR V PEL+LS DQQSLA YA++VRYGTDE Sbjct 301 WYAARREGLALDGAGDTFSTPQRVQDALRA-VSPELKLSLLDQQSLAPYAKVVRYGTDET 359 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 VQ AGVVP G++F+IAGSVRL VT DG VA+ TL KG FLG+TALTRQP+P GAVALE Sbjct 360 VQQAGVVPKGMSFIIAGSVRLMVTPADGPAVAVGTLGKGAFLGVTALTRQPNPGGAVALE 419 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRD 464 EVT L I RE+LE++VM+KP LLQELGR+IDERQ K +Q +R+ Sbjct 420 EVTVLDIDREYLERIVMSKPALLQELGRLIDERQMKVRQVTQRE 463 >gi|118618965|ref|YP_907297.1| hypothetical protein MUL_3699 [Mycobacterium ulcerans Agy99] gi|118571075|gb|ABL05826.1| conserved hypothetical membrane protein [Mycobacterium ulcerans Agy99] Length=466 Score = 675 bits (1742), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/464 (75%), Positives = 400/464 (87%), Gaps = 1/464 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MN+L ++WF+WA+GIAIG+P LI+LTELHN L RRNSHLARQ +LLRN+LLPLGA+LL Sbjct 1 MNVLGASWFHWAIGIAIGVPVDLILLTELHNSLARRNSHLARQVTLLRNFLLPLGALLLF 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LVKAS+VPA + TVR+LTT FGFLVLVLLLS LNAT+F APQ SWRKRLP IF+DVARF Sbjct 61 LVKASQVPAGEGTVRILTTVFGFLVLVLLLSALNATVFASAPQDSWRKRLPTIFLDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALIGIGLA+ILSY+WGVRVGG+F ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 121 ALIGIGLAMILSYVWGVRVGGIFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+TPTARGRVVEVNWRAVHI+TG+GL+I PNS+LATTAFTNLSRP G+H+CSITT F+ Sbjct 181 WLDTPTARGRVVEVNWRAVHIETGTGLRITPNSVLATTAFTNLSRPGGSHKCSITTKFAA 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 D PDKVCAML R ASALP++K GV+PAT+A G AEYRTTVR+ SPA++G Q TFLRWV Sbjct 241 DDAPDKVCAMLTRVASALPNLKSGVMPATVALGGAEYRTTVRIKSPAEDGAAQDTFLRWV 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARREGL LD A D +ST +RV+ ALR V PEL+LS DQQSLA YA++VRYGTDE Sbjct 301 WYAARREGLALDGAGDSYSTPQRVQDALRA-VSPELKLSLLDQQSLAPYAKVVRYGTDET 359 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 VQ AGVVP G++F+IAGSVRL VT DG V + TL KG FLG+TALTRQP+P GAVALE Sbjct 360 VQQAGVVPKGMSFIIAGSVRLMVTPADGPAVVVGTLGKGVFLGVTALTRQPNPGGAVALE 419 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRD 464 EVT L I RE+LE++VM+KP LLQELGR+IDE+Q K +Q +R+ Sbjct 420 EVTVLDIDREYLERIVMSKPALLQELGRLIDEQQMKVRQVTQRE 463 >gi|296170505|ref|ZP_06852092.1| cyclic nucleotide-binding protein [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894857|gb|EFG74579.1| cyclic nucleotide-binding protein [Mycobacterium parascrofulaceum ATCC BAA-614] Length=481 Score = 648 bits (1671), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/464 (71%), Positives = 385/464 (83%), Gaps = 0/464 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MNL +S+WFYWA+GIA+G P GLI+LTELH LVRR SHLARQ SLLRNYLLPLGA+LLL Sbjct 1 MNLFESSWFYWAIGIAVGFPVGLILLTELHRALVRRRSHLARQVSLLRNYLLPLGALLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 +VK S+VPA D +VR+LTT FG LVLVL+LS LNAT+F+GAP+ SWRKRLPAIFVDVARF Sbjct 61 VVKVSQVPAGDGSVRILTTVFGLLVLVLVLSALNATVFEGAPEDSWRKRLPAIFVDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 +IG+GLA++LSYIWGVR+GGLF ALG+TSVVIGLMLQNSVGQ+VSGLFMLFEQPFRIDD Sbjct 121 GVIGVGLALMLSYIWGVRIGGLFTALGITSVVIGLMLQNSVGQVVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+T T RGRVVEVNWR+VHIDTGSG++IMPNSMLA T+FTNLSRP A++C+I T F+ Sbjct 181 WLDTGTTRGRVVEVNWRSVHIDTGSGIRIMPNSMLAGTSFTNLSRPPRAYDCAIATKFAA 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 D PD+VCAML R A ALP KP P T+A G +YRTTVRL SPAD T+ATFLRWV Sbjct 241 GDAPDRVCAMLTRVAGALPARKPEASPTTVALGGGQYRTTVRLLSPADAEATEATFLRWV 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARR L LD ADD +ST RVE ALRTVV P LRLS +DQQSL YA++VRYG DE+ Sbjct 301 WYAARRARLRLDGADDNYSTKPRVEKALRTVVAPALRLSHTDQQSLVPYAKIVRYGADEV 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 ++ G V G+TF+I G VRLT T DDGSV+ ++ L +G+FLGLTALTRQP+ AGA AL Sbjct 361 IESTGQVSSGMTFLIEGRVRLTATADDGSVIPVSVLDEGSFLGLTALTRQPNLAGAYALG 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRD 464 EVTAL I REHLE +VM KP+LLQ+LGR+IDERQ K ++A R + Sbjct 421 EVTALHIDREHLEHLVMRKPLLLQDLGRLIDERQTKVREATRHE 464 >gi|254819844|ref|ZP_05224845.1| hypothetical protein MintA_07964 [Mycobacterium intracellulare ATCC 13950] Length=467 Score = 625 bits (1612), Expect = 5e-177, Method: Compositional matrix adjust. Identities = 322/462 (70%), Positives = 382/462 (83%), Gaps = 0/462 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MN+ S+WFYWAVGIAIGLP G+I+LTELH+ L+RR S LARQ LLRNYLLPL A+LLL Sbjct 1 MNIFGSSWFYWAVGIAIGLPVGMILLTELHDALLRRQSPLARQVGLLRNYLLPLAALLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LV+AS +PA D VR+LTT FG LV+VLLLS LNAT+F+ AP++SWRKRLP IF+DVAR Sbjct 61 LVQASGIPAGDIPVRILTTVFGLLVVVLLLSGLNATVFERAPEKSWRKRLPTIFIDVARI 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALI +GLAV+ SYIWGVR+GG+F ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 121 ALICVGLAVMSSYIWGVRIGGVFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+T TARGRVVEVNWRAVHIDTGSG++IMPN+ LATT+FTNLSRP G H+ +ITTTFS Sbjct 181 WLDTGTARGRVVEVNWRAVHIDTGSGIRIMPNAALATTSFTNLSRPPGPHKVAITTTFSA 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 +D PD+VCA+L+R A ALP +KPG VP ++ GA EYRTT+ L SPAD G ATFLRW Sbjct 241 ADAPDRVCAVLSRVARALPQLKPGSVPRSVPVGAGEYRTTIGLDSPADAGAATATFLRWA 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARRE LHLD+ADD+FST ERVE AL VV P LRLS+ +Q+SL AR+VRYGTDE+ Sbjct 301 WYAARRENLHLDDADDDFSTVERVEHALHEVVAPALRLSTEEQRSLRSSARIVRYGTDEL 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 V+ AG VP +TF++AG V+LT T DDG+VV I+TL +G FLGLTALTRQP+ A A A+E Sbjct 361 VEDAGQVPTAMTFLVAGRVQLTATADDGTVVPISTLSEGAFLGLTALTRQPNLASAYAVE 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIR 462 EVTAL+I REH+E +VM P LLQ G +++ER+ K + A R Sbjct 421 EVTALEIDREHIEHLVMRAPALLQNFGTILEERRSKVRTARR 462 >gi|342857829|ref|ZP_08714485.1| hypothetical protein MCOL_03105 [Mycobacterium colombiense CECT 3035] gi|342135162|gb|EGT88328.1| hypothetical protein MCOL_03105 [Mycobacterium colombiense CECT 3035] Length=467 Score = 623 bits (1607), Expect = 2e-176, Method: Compositional matrix adjust. Identities = 320/462 (70%), Positives = 387/462 (84%), Gaps = 0/462 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MNL +STWFYWA+GIA+GLP GLI LTELH+ L+RRNS LARQ LLRNYLLPLGA+LLL Sbjct 1 MNLFNSTWFYWAIGIAVGLPLGLIALTELHDALLRRNSPLARQVGLLRNYLLPLGALLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LV+AS+VPA+D VRVLTT FG LVLVLLLS LNAT+F+GAP++SWRKRLP IF+D AR Sbjct 61 LVQASQVPADDVPVRVLTTVFGLLVLVLLLSGLNATMFEGAPEKSWRKRLPTIFLDCARL 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 A+IG+GLAV+ SYIWGVR+GG+F ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRID+ Sbjct 121 AVIGVGLAVMSSYIWGVRIGGIFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDE 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+T TARGRVVEVNWR+VHIDTGSG+++MPNSMLA+ AFTNLSRP GAH+ ++TT FS+ Sbjct 181 WLDTGTARGRVVEVNWRSVHIDTGSGIRVMPNSMLASNAFTNLSRPPGAHKLAVTTMFSS 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 DPPD+VCA+L+R A LP +K G VP T+ GA EYRTT+ L SPAD G +ATFLRW Sbjct 241 VDPPDRVCAVLSRIAQGLPQLKAGSVPRTVPVGAGEYRTTIGLDSPADAGAAKATFLRWA 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYA RRE LHLD+ADD+FST ERVE AL TVV P LR+ + +Q+SL AR+VRYG DE+ Sbjct 301 WYATRREELHLDDADDDFSTVERVEHALHTVVAPALRIGAEEQRSLRSAARIVRYGADEV 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 V++AG VP +TF+++G V+LT T DDG++V I+TL +G+FLGLTALTRQP+ A A AL+ Sbjct 361 VEYAGQVPTTMTFLVSGRVQLTATADDGALVPISTLVEGSFLGLTALTRQPNLASAYALD 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIR 462 EVTAL+I REH+E +V P+LLQ G +I+ER+ K + A R Sbjct 421 EVTALEIDREHIEHLVTRAPVLLQNFGNIIEERRSKVRSARR 462 >gi|254774562|ref|ZP_05216078.1| hypothetical protein MaviaA2_07813 [Mycobacterium avium subsp. avium ATCC 25291] Length=467 Score = 599 bits (1544), Expect = 4e-169, Method: Compositional matrix adjust. Identities = 315/462 (69%), Positives = 374/462 (81%), Gaps = 0/462 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MN S+WFYWA+GIAIGLP G+I LTE+H+ L+RR S LARQ LLRNYLLPLGA+LL Sbjct 1 MNAFGSSWFYWAIGIAIGLPIGMIALTEIHDALLRRQSPLARQVGLLRNYLLPLGALLLF 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LV+AS +PA VR+LTTAFG LVLVLLLS LNAT+F+ AP++SWRKRLP IF+DVAR Sbjct 61 LVQASGIPAGHIPVRILTTAFGLLVLVLLLSGLNATVFERAPEKSWRKRLPTIFIDVARL 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALI +GLAV+ SYIWGVR+GGLF ALG+TSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 121 ALICVGLAVMSSYIWGVRIGGLFTALGITSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+T T GRVVEVNWR+VHIDTG+G++IMPNSMLATT+F NLSRP G H+ +I TTFST Sbjct 181 WLDTGTTSGRVVEVNWRSVHIDTGAGIRIMPNSMLATTSFINLSRPPGPHKVAIDTTFST 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 +D PD+VCA L+R A ALP VKPG V T+ GAA YRT + L SPAD G +ATFLRW Sbjct 241 ADAPDRVCATLSRVARALPQVKPGTVTRTVPVGAAGYRTVIWLDSPADAGAAKATFLRWA 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARRE LHLD ADD+FST +RVE AL TVV LRLS+ +Q+SL AR+VRYG DEI Sbjct 301 WYAARREELHLDGADDDFSTVQRVEHALDTVVAAALRLSTEEQRSLRSAARIVRYGADEI 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 V+ AG VP +TF+++G V+LT T +DG+VV ++TL +G FLGLTALTRQP+ A A ALE Sbjct 361 VEDAGQVPSAMTFLVSGRVQLTATAEDGTVVPVSTLTEGEFLGLTALTRQPNLASAYALE 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIR 462 EVTAL+I REH+E +V P LLQ GR+++ER+ K + A R Sbjct 421 EVTALEIDREHIEHLVTRAPALLQNFGRILEERRSKVRGARR 462 >gi|240170839|ref|ZP_04749498.1| hypothetical protein MkanA1_16117 [Mycobacterium kansasii ATCC 12478] Length=467 Score = 598 bits (1541), Expect = 8e-169, Method: Compositional matrix adjust. Identities = 309/464 (67%), Positives = 380/464 (82%), Gaps = 0/464 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MN+ ++WFYWAV +A+GLP +++LTEL + L RR SHLARQ SLLRNYLLPLGA+LLL Sbjct 1 MNIFGASWFYWAVSVALGLPVLIVILTELQHTLRRRGSHLARQISLLRNYLLPLGALLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 +V + VPA D VR+LTT FGFLVLVLLLS LNAT+F APQ SWRKRLP IF+DVARF Sbjct 61 IVNSEGVPAHDNAVRILTTVFGFLVLVLLLSGLNATVFAAAPQGSWRKRLPVIFLDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 LIG GLAVILSY+WGVR+GGLF A+GVTSVVIGLMLQNSVGQIVSGLFMLFEQPF+IDD Sbjct 121 VLIGAGLAVILSYVWGVRIGGLFTAVGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFQIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+T TARGR+VEVNWRAVHIDTGSGL+I PNS+LA+T FTNLSRPAG ++ ++ TTFS Sbjct 181 WLDTSTARGRIVEVNWRAVHIDTGSGLRITPNSVLASTPFTNLSRPAGGYQLAMKTTFSD 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 +D PD+VCA+L+R A+ LP + G +P + G AEY TT+ L SPADE +ATFLRW+ Sbjct 241 ADSPDRVCALLSRIAAELPQLHSGFIPTSEPLGGAEYCTTIGLRSPADESDARATFLRWI 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARRE LHLD ADD+FST ER+ AL+ VVGP LRL+ +DQQ+L +ARL+RYG EI Sbjct 301 WYAARREKLHLDGADDDFSTTERLRDALKAVVGPALRLNDADQQTLLSHARLLRYGAGEI 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 VQ AG VP+ + FV+ G VRLT T DDGSVV I TL++G FLGLTALTRQP+ + A A++ Sbjct 361 VQCAGEVPVEMMFVVTGLVRLTATADDGSVVPITTLEEGGFLGLTALTRQPNLSNAYAID 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRD 464 EVT ++IGREH+E +VM +P+LLQ+ G +++ERQ + +Q++ R+ Sbjct 421 EVTTVEIGREHVEHLVMRQPLLLQDFGHILEERQSQVRQSLHRE 464 >gi|118466400|ref|YP_882384.1| transmembrane protein [Mycobacterium avium 104] gi|118167687|gb|ABK68584.1| probable conserved transmembrane protein [Mycobacterium avium 104] Length=473 Score = 591 bits (1524), Expect = 9e-167, Method: Compositional matrix adjust. Identities = 300/461 (66%), Positives = 363/461 (79%), Gaps = 0/461 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 M+ DS+ YWA + GLP LIVLTE H LVR++S LAR A LLR+YL+PLGA+L+L Sbjct 1 MSTFDSSSLYWATAVVFGLPLLLIVLTEWHQSLVRKHSPLARPAFLLRSYLIPLGALLVL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LV + +PA+ +VRVL TAFGF+V+VLLLS LNAT+F+GAP+ SWR+R+P IF+DV RF Sbjct 61 LVNVARMPAQFTSVRVLATAFGFVVVVLLLSGLNATIFEGAPEGSWRQRVPGIFLDVTRF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 LIG+GLAVI SY+WGVRVGGLF ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRI D Sbjct 121 VLIGVGLAVIFSYVWGVRVGGLFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIGD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+TP ARGR+VE NWR+VHI TG GLQI PNS+LATT+FTNLSRP G H+ ++T TFS Sbjct 181 WLDTPAARGRIVEANWRSVHIQTGHGLQITPNSVLATTSFTNLSRPPGGHQLTLTATFSE 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 +DPPD+VCA+L R A ALP +P V A + G EY T+ LTSPAD+ QAT LRW+ Sbjct 241 TDPPDRVCALLRRVADALPQRRPDAVAAAVPAGGGEYHVTIGLTSPADDSAAQATLLRWL 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WY ARREGL LD A+D+ ST ER+E ALR VV P LRL DQQ+L +AR+VRYG DEI Sbjct 301 WYGARREGLRLDGAEDDISTPERIERALRMVVAPALRLGPPDQQALVSHARIVRYGADEI 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 V+HAG VP +TF++AG VRLT T DGSVVA+ L +G+FLG+TALTRQP+ A A A+ Sbjct 361 VEHAGRVPEKMTFLLAGGVRLTATAPDGSVVAVGGLDEGSFLGVTALTRQPNLADAQAVA 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAI 461 EVTAL+I REHL ++V KP+LLQ+LGR IDER+ +A+ Sbjct 421 EVTALEIDREHLVELVTGKPLLLQDLGRTIDERRALVHRAV 461 >gi|254775650|ref|ZP_05217166.1| transmembrane protein [Mycobacterium avium subsp. avium ATCC 25291] Length=473 Score = 587 bits (1513), Expect = 2e-165, Method: Compositional matrix adjust. Identities = 299/461 (65%), Positives = 362/461 (79%), Gaps = 0/461 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 M+ DS+ YWA + GLP LIVLTE H LVR++S LAR LLR+YL+PLGA+L+L Sbjct 1 MSTFDSSSLYWAAAVVFGLPLLLIVLTEWHQSLVRKHSPLARPVFLLRSYLIPLGALLVL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LV + +PA+ +VRVL TAFGF+V+VLLLS LNAT+F+GAP+ SWR+R+P IF+DV RF Sbjct 61 LVNVARMPAQFTSVRVLATAFGFVVVVLLLSGLNATIFEGAPEGSWRQRVPGIFLDVTRF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 LIG+GLAVI SY+WGVRVGGLF ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRI D Sbjct 121 VLIGVGLAVIFSYVWGVRVGGLFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIGD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+TP ARGR+VE NWR+VHI TG GLQI PNS+LATT+FTNLSRP G H+ ++T TFS Sbjct 181 WLDTPAARGRIVEANWRSVHIQTGHGLQITPNSVLATTSFTNLSRPPGGHQLTLTATFSE 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 +DPPD+VCA+L R A ALP +P V A + G AEY T+ LTSPAD+ QAT LRW+ Sbjct 241 TDPPDRVCALLRRVADALPQRRPDAVAAAVPAGGAEYHVTIGLTSPADDSAAQATLLRWL 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WY ARREGL LD A+D+ ST ER+E ALR VV P LRL DQQ+L +AR+VRYG DEI Sbjct 301 WYGARREGLRLDGAEDDISTPERIERALRMVVAPALRLGPPDQQALVSHARIVRYGADEI 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 V+HAG VP +TF++AG VRLT DGSVVA+ L +G+FLG+TALTRQP+ A A A+ Sbjct 361 VEHAGRVPEKMTFLLAGGVRLTAAAPDGSVVAVGGLDEGSFLGVTALTRQPNLADAQAVA 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAI 461 EVTAL+I REHL ++V KP+LLQ+LGR IDER+ +A+ Sbjct 421 EVTALEIDREHLVELVTGKPLLLQDLGRTIDERRALVHRAV 461 >gi|254820708|ref|ZP_05225709.1| transmembrane protein [Mycobacterium intracellulare ATCC 13950] Length=468 Score = 583 bits (1502), Expect = 3e-164, Method: Compositional matrix adjust. Identities = 303/465 (66%), Positives = 371/465 (80%), Gaps = 0/465 (0%) Query 4 LDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLLVK 63 +DS+ YWA G+ IGLP LI LTE H LVRR+S LAR A LLR+YL+PLGA+L+LLV Sbjct 1 MDSSSLYWAAGVVIGLPLLLIALTEWHQSLVRRDSPLARPAFLLRSYLIPLGALLVLLVN 60 Query 64 ASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALI 123 + +PA+ +VRVL T FGF+VLVLLLS LNAT+F+GAPQ +WR+R+P IF+DV RF LI Sbjct 61 VARMPAQFTSVRVLATVFGFVVLVLLLSGLNATVFEGAPQGTWRQRIPGIFLDVTRFVLI 120 Query 124 GIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLE 183 G+GLAVI SY+WGVRVGGLF ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRI DWL+ Sbjct 121 GVGLAVIFSYVWGVRVGGLFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIGDWLD 180 Query 184 TPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDP 243 TP ARGR+VE NWR+VHI TG GLQI PNS+LATT+FTNLSRP G H+ +ITTTFS DP Sbjct 181 TPAARGRIVEANWRSVHIQTGRGLQITPNSVLATTSFTNLSRPPGGHQLAITTTFSEVDP 240 Query 244 PDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYA 303 PD+VCA+L R A+ALP +P V A GAAEY TV L SPAD+ QATFLRW+WYA Sbjct 241 PDRVCALLERVANALPQRRPNAVAAATPAGAAEYLLTVGLRSPADDSAAQATFLRWLWYA 300 Query 304 ARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQH 363 ARREGL LD +D+ ST ER+E ALRTVV P LRLS DQQ+L +AR+VRYG +EIV+H Sbjct 301 ARREGLRLDGTEDDISTPERIEKALRTVVAPALRLSQPDQQALTSHARIVRYGANEIVEH 360 Query 364 AGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVT 423 AG VP +TF++AG VRLT T DG+ VA+ L +G+FLG+TALTRQP+ + A A++E+T Sbjct 361 AGRVPDKMTFLLAGGVRLTATARDGTAVAVGGLDEGSFLGVTALTRQPNLSDAQAIDEIT 420 Query 424 ALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQS 468 AL+I R+HL ++V +KP+LLQ+LGR IDER+ + +A+ ++ S Sbjct 421 ALEIDRDHLVELVTSKPLLLQDLGRAIDERRARVHEAMGQEFALS 465 >gi|336457929|gb|EGO36920.1| small-conductance mechanosensitive channel [Mycobacterium avium subsp. paratuberculosis S397] Length=474 Score = 581 bits (1498), Expect = 8e-164, Method: Compositional matrix adjust. Identities = 297/462 (65%), Positives = 363/462 (79%), Gaps = 1/462 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 M+ DS+ YWA + +GLP LIV TE H LVR++S LAR LLR+YL+PLGA+L+L Sbjct 1 MSTFDSSSLYWAAAVVLGLPLLLIVFTEWHQSLVRKHSPLARPVFLLRSYLIPLGALLVL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLL-SLLNATLFQGAPQQSWRKRLPAIFVDVAR 119 LV + +PA+ +VRVL TAFGF+V+V+LL S LNAT+F+GAP+ SWR+R+P IF+DV R Sbjct 61 LVNVARMPAQFTSVRVLATAFGFVVVVVLLLSGLNATVFEGAPEGSWRQRVPGIFLDVTR 120 Query 120 FALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRID 179 F LIG+GLAVI SY+WGVRVGGLF ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRI Sbjct 121 FVLIGVGLAVIFSYVWGVRVGGLFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIG 180 Query 180 DWLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFS 239 DWL+TP ARGR+VE NWR+VHI TG GLQI PNS+LATT+FTNLSRP G H+ ++T TFS Sbjct 181 DWLDTPAARGRIVEANWRSVHIQTGRGLQITPNSVLATTSFTNLSRPPGGHQLTLTATFS 240 Query 240 TSDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRW 299 +DPPD+VCA+L R A ALP +P V A ++ G AEY T+ LTSPAD+ QAT LRW Sbjct 241 ETDPPDRVCALLRRVADALPQRRPDAVAAAVSAGGAEYHVTIGLTSPADDSAAQATLLRW 300 Query 300 VWYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDE 359 +WY ARREGL LD A+D+ ST ER+E ALR VV P LRL DQQ+L +AR+VRYG DE Sbjct 301 LWYGARREGLRLDGAEDDISTPERIERALRMVVAPALRLGPPDQQALVSHARIVRYGADE 360 Query 360 IVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVAL 419 IV+HAG VP +TF++AG VRLT DGSVVA+ L +G+FLG+TALTRQP+ A A A+ Sbjct 361 IVEHAGRVPEKMTFLLAGGVRLTAAAPDGSVVAVGGLDEGSFLGVTALTRQPNLADAQAV 420 Query 420 EEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAI 461 EVTAL+I REHL ++V KP+LLQ+LGR IDER+ +A+ Sbjct 421 AEVTALEIDREHLVELVTGKPLLLQDLGRTIDERRALVHRAV 462 >gi|183983734|ref|YP_001852025.1| hypothetical protein MMAR_3754 [Mycobacterium marinum M] gi|183177060|gb|ACC42170.1| conserved hypothetical membrane protein [Mycobacterium marinum M] Length=464 Score = 575 bits (1481), Expect = 7e-162, Method: Compositional matrix adjust. Identities = 301/459 (66%), Positives = 370/459 (81%), Gaps = 0/459 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 M++ S WFYWAVGIA LP +++LTE+ +L RR S LARQ LLRNY+LPLGA+LLL Sbjct 1 MSVFGSAWFYWAVGIAAALPVLVVILTEVQRLLRRRQSALARQVGLLRNYVLPLGALLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 +V A+ VPA D VR+L T FGFLVLVLLLS LNA +F GAPQ SWR+RLP IFVDVARF Sbjct 61 MVNATGVPAHDTAVRLLATVFGFLVLVLLLSGLNAAVFSGAPQGSWRRRLPVIFVDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 LIG GLAVILS++WGVR+GGLF ALGVTSVVIGLMLQNSV QIVSGLFMLFEQPF+IDD Sbjct 121 VLIGAGLAVILSFVWGVRIGGLFTALGVTSVVIGLMLQNSVSQIVSGLFMLFEQPFQIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+T T RGR+VEVNWRAVHI+TGSGL+I PNS+LA+T FTNLSRPAGA++ +I T FS Sbjct 181 WLDTTTTRGRIVEVNWRAVHIETGSGLRITPNSVLASTPFTNLSRPAGAYQLAIPTKFSD 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 +D PD+VCA+L+R A+ALP + G + T G EY TT+ L SPA+E +ATFLRW+ Sbjct 241 ADAPDRVCALLSRVAAALPQLDGGFLVTTEPVGGTEYCTTIGLRSPAEESAARATFLRWI 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARREGLHL+ ADD+FST ERV+ AL+TVV P +RLS +DQQ+L AR++R+ E Sbjct 301 WYAARREGLHLNGADDDFSTTERVQHALKTVVAPVMRLSDTDQQALLSSARIIRFAAGET 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 +++AG VP G+TF+I G VRLT T +DGSVV + TL +G FLGLTALTRQP+ AGA AL+ Sbjct 361 MEYAGQVPAGMTFLITGRVRLTATAEDGSVVPVTTLHEGGFLGLTALTRQPNLAGAHALD 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQ 459 EVTAL++ REHLE +VM +P+LLQ+ G +++ERQ K ++ Sbjct 421 EVTALEVDREHLEHLVMREPLLLQDFGHILEERQSKVRR 459 >gi|333990120|ref|YP_004522734.1| transmembrane protein [Mycobacterium sp. JDM601] gi|333486088|gb|AEF35480.1| transmembrane protein [Mycobacterium sp. JDM601] Length=454 Score = 573 bits (1476), Expect = 3e-161, Method: Compositional matrix adjust. Identities = 306/454 (68%), Positives = 365/454 (81%), Gaps = 4/454 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MN+L WFYWAVG+A G PAGLI+LTE H L RR S+LAR +L+RNYLLPLGA+L+L Sbjct 1 MNIL-GPWFYWAVGVAAGFPAGLILLTEWHVALTRRGSYLARPVALVRNYLLPLGALLVL 59 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 L + + VPA+DPTVRV+ T FGF++LVLLLS LN T FQ AP+ SWR R P IFVDVARF Sbjct 60 LGQVAAVPAQDPTVRVIYTLFGFVLLVLLLSGLNVTFFQSAPKGSWRGRFPTIFVDVARF 119 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 LIG+GLA+ILSY+WG ++GGLF ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRI D Sbjct 120 LLIGVGLALILSYVWGAKIGGLFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIGD 179 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL TPTARGRVVEVNWRAVHI T GLQ+ PNS+LA+T+FTN+SR GAH SITTTF+ Sbjct 180 WLSTPTARGRVVEVNWRAVHISTAGGLQVTPNSVLASTSFTNVSRSGGAHRVSITTTFAV 239 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 SDPPD+VCA+L+R A+ALP G P ++A G EYRTTV L SP D+GP QATFLRW+ Sbjct 240 SDPPDRVCALLSRVATALPLRTTGEAPGSVALGGGEYRTTVALDSPDDDGPAQATFLRWL 299 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARREGLHLD++DD FST ERV ALRTVV P LRL+ +DQQ++A YA +VRYG DE+ Sbjct 300 WYAARREGLHLDDSDDVFSTPERVAEALRTVVAPALRLTDADQQAVAPYAAVVRYGADEV 359 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 ++ AG VP + F+ GSVRL TT+D +V ATL+ G FLG+T LTRQ A A+E Sbjct 360 LEQAGHVPTAMIFLTEGSVRL--TTEDPAVPG-ATLRHGAFLGVTTLTRQASQFDARAVE 416 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQ 454 EVTA+ I REH+E++VM KP+LLQELGR+ID+R+ Sbjct 417 EVTAVVIDREHIEELVMAKPLLLQELGRIIDQRR 450 >gi|342860845|ref|ZP_08717495.1| transmembrane protein [Mycobacterium colombiense CECT 3035] gi|342131869|gb|EGT85126.1| transmembrane protein [Mycobacterium colombiense CECT 3035] Length=456 Score = 572 bits (1475), Expect = 4e-161, Method: Compositional matrix adjust. Identities = 299/446 (68%), Positives = 357/446 (81%), Gaps = 0/446 (0%) Query 15 IAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLLVKASEVPAEDPTV 74 + GLP LI LTE H LVR+ S LAR LLR+YL+PLGA+L+LLV + +PA+ +V Sbjct 1 MVFGLPLLLIALTEWHQGLVRKASPLARPVLLLRSYLVPLGALLVLLVNVARMPAQFTSV 60 Query 75 RVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALIGIGLAVILSYI 134 RVL T FGF+VLVLLLS LNAT+F+GAPQ SWR+R+P IF+DV RF LIG+GLAVI SY+ Sbjct 61 RVLATVFGFVVLVLLLSGLNATVFEGAPQGSWRQRIPGIFLDVTRFVLIGVGLAVIFSYV 120 Query 135 WGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVVEV 194 WGVRVGGLF ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRI DWL+TP+ARGR+VE Sbjct 121 WGVRVGGLFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIGDWLDTPSARGRIVEA 180 Query 195 NWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAMLNRA 254 NWRAVHI++G GLQI PNS+LATT+FTNLSRP G H+ +ITTTFS DPPD+VCA+L R Sbjct 181 NWRAVHIESGRGLQITPNSVLATTSFTNLSRPPGGHQLAITTTFSEIDPPDRVCALLERV 240 Query 255 ASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAARREGLHLDEA 314 A ALP +P V + G AEYR TV L SPAD+ A FLRW+WYAARREGLHLD A Sbjct 241 ADALPQRRPDTVASAAPTGGAEYRVTVGLKSPADDAAAHAAFLRWLWYAARREGLHLDGA 300 Query 315 DDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFV 374 +D+ ST ER+E A+RTVV P LRLS DQQ+L +AR+VRYG DEIV+HAG VP G+TF+ Sbjct 301 EDDISTTERIERAVRTVVAPALRLSQPDQQALVSHARIVRYGADEIVEHAGRVPAGMTFL 360 Query 375 IAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQ 434 I G VRLT DGSV A+ L +G+FLG+TALTRQP+ A A A++EVTAL+I R+HL + Sbjct 361 IEGGVRLTAIATDGSVAAVGGLDEGSFLGVTALTRQPNLADAQAIDEVTALEIDRDHLVE 420 Query 435 VVMNKPMLLQELGRVIDERQRKAQQA 460 +VM+KP+LLQELGR IDER+ + Q A Sbjct 421 LVMDKPLLLQELGRTIDERRARVQAA 446 >gi|118618963|ref|YP_907295.1| hypothetical protein MUL_3697 [Mycobacterium ulcerans Agy99] gi|118571073|gb|ABL05824.1| conserved hypothetical membrane protein [Mycobacterium ulcerans Agy99] Length=464 Score = 568 bits (1463), Expect = 9e-160, Method: Compositional matrix adjust. Identities = 299/459 (66%), Positives = 369/459 (81%), Gaps = 0/459 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 M++ S WFYWAVGIA LP +++LTE+ +L RR S LARQ LLRNY+LPLGA+LLL Sbjct 1 MSVFGSAWFYWAVGIAAALPVLVVILTEVQRLLRRRQSALARQVGLLRNYVLPLGALLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LV A+ VPA D VR+L T FGFLVLVLLLS LNA +F GAPQ SWR+RLP IFVDVARF Sbjct 61 LVNATGVPAHDTAVRLLATVFGFLVLVLLLSGLNAAVFSGAPQGSWRRRLPVIFVDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 LIG GLAVILS++WGVR+GGLF ALGVTSVVIGLMLQNSV QIVSGLFMLFEQPF+IDD Sbjct 121 VLIGAGLAVILSFVWGVRIGGLFTALGVTSVVIGLMLQNSVSQIVSGLFMLFEQPFQIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+T T RGR+VEVNWRAV I+TGSGL+I PNS+LA+T FTNLSRPAGA++ +I T FS Sbjct 181 WLDTTTTRGRIVEVNWRAVRIETGSGLRITPNSVLASTPFTNLSRPAGAYQLAIPTKFSD 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 +D PD+VCA+L+R A+ALP + G + T G EY TT+ L SPA+E +ATFLRW+ Sbjct 241 ADAPDRVCALLSRVAAALPQLDGGFLVTTEPVGGTEYCTTIGLRSPAEESAARATFLRWI 300 Query 301 WYAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEI 360 WYAARREGLHL+ ADD+FST ERV+ AL+TVV P +RLS +DQQ+L AR++R+ + Sbjct 301 WYAARREGLHLNGADDDFSTTERVQHALKTVVAPVMRLSDTDQQALLSSARIIRFAAGDT 360 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALE 420 +++AG VP G+TF+I G VRLT T +DGS+V + TL +G FLGLTALTRQP+ AGA AL+ Sbjct 361 MEYAGQVPAGMTFLITGRVRLTATAEDGSIVPVTTLHEGGFLGLTALTRQPNLAGAHALD 420 Query 421 EVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQ 459 EVTAL++ REHLE +VM +P+LLQ+ G +++ERQ K ++ Sbjct 421 EVTALEVDREHLEHLVMREPLLLQDFGHILEERQSKVRR 459 >gi|118473923|ref|YP_887882.1| transmembrane protein [Mycobacterium smegmatis str. MC2 155] gi|118175210|gb|ABK76106.1| probable conserved transmembrane protein [Mycobacterium smegmatis str. MC2 155] Length=464 Score = 543 bits (1399), Expect = 3e-152, Method: Compositional matrix adjust. Identities = 268/463 (58%), Positives = 351/463 (76%), Gaps = 1/463 (0%) Query 2 NLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLL 61 ++L++ WFYWA+ +A+GLP GL++LTELHN L R S+LAR SLLRNY+LPL A+L+LL Sbjct 3 SVLEANWFYWALSVAVGLPIGLVLLTELHNTLARHGSYLARPVSLLRNYILPLAALLILL 62 Query 62 VKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFA 121 VK SE+ AE VR++ T FGF+V++LLLS LNATLFQGAP+ SWRKR+P+IF+DVARFA Sbjct 63 VKGSEISAEATPVRIVATGFGFVVIILLLSGLNATLFQGAPEGSWRKRIPSIFLDVARFA 122 Query 122 LIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDW 181 LI +G+ +I++Y+WG VGGLF ALGVTS+V+GL LQN+VGQI+SGL +LFEQPF++ DW Sbjct 123 LIAVGVGMIMAYVWGANVGGLFTALGVTSIVLGLALQNAVGQIISGLLLLFEQPFQLGDW 182 Query 182 LETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTS 241 L+TP+ARGRVVEVNWRA HIDTG GLQIMPNS+LA +FTNLSRP AH S+TTTF S Sbjct 183 LDTPSARGRVVEVNWRATHIDTGGGLQIMPNSVLAGASFTNLSRPEAAHSLSVTTTFGVS 242 Query 242 DPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVW 301 D PD VCA+L R A+ LP + G P I GA EY+T++ L +PAD+ +A FLRW+W Sbjct 243 DSPDAVCALLTRVATQLPQRRAGAAPKAIPLGAGEYKTSIPLRTPADDSAARAVFLRWLW 302 Query 302 YAARREGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIV 361 YAARR LHLD D+FST ER+ A+R + P LRLS ++QQ + ++ LVR+G DEI+ Sbjct 303 YAARRAELHLDGETDDFSTPERLTKAVRQ-MAPTLRLSHTEQQEVLNHSALVRFGADEII 361 Query 362 QHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEE 421 Q AG +P ++F+++G V ++V D +V+ + TL + FLG TALTR+ A A AL E Sbjct 362 QEAGEIPTRMSFIVSGRVGVSVAGDGDAVIPVRTLTENDFLGQTALTREGALASAHALTE 421 Query 422 VTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRD 464 T LQI RE LE++V P+LL EL R+ID+R+ A+ A+ D Sbjct 422 TTVLQISREFLEELVAGNPLLLLELSRIIDDRRSAARAALTAD 464 >gi|289758566|ref|ZP_06517944.1| cyclic nucleotide-binding protein [Mycobacterium tuberculosis T85] gi|289714130|gb|EFD78142.1| cyclic nucleotide-binding protein [Mycobacterium tuberculosis T85] gi|339295328|gb|AEJ47439.1| cyclic nucleotide-binding protein [Mycobacterium tuberculosis CCDC5079] gi|339298946|gb|AEJ51056.1| cyclic nucleotide-binding protein [Mycobacterium tuberculosis CCDC5180] Length=266 Score = 484 bits (1247), Expect = 1e-134, Method: Compositional matrix adjust. Identities = 243/243 (100%), Positives = 243/243 (100%), Gaps = 0/243 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL Sbjct 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF Sbjct 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD Sbjct 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST Sbjct 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 Query 241 SDP 243 SDP Sbjct 241 SDP 243 >gi|336458216|gb|EGO37197.1| small-conductance mechanosensitive channel [Mycobacterium avium subsp. paratuberculosis S397] Length=331 Score = 445 bits (1144), Expect = 9e-123, Method: Compositional matrix adjust. Identities = 218/326 (67%), Positives = 261/326 (81%), Gaps = 0/326 (0%) Query 137 VRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVVEVNW 196 +R+GGLF ALG+TSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWL+T T GRVVEVNW Sbjct 1 MRIGGLFTALGITSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLDTGTTSGRVVEVNW 60 Query 197 RAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAMLNRAAS 256 R+VHIDTG+G++IMPNSMLATT+F NLSRP G H+ +I TTFST+D PD+VCA L+R A Sbjct 61 RSVHIDTGAGIRIMPNSMLATTSFINLSRPPGPHKVAIDTTFSTADAPDRVCATLSRVAR 120 Query 257 ALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAARREGLHLDEADD 316 ALP VKPG V T+ GAA YRT + L SPAD G +ATFLRW WYAARRE LHLD ADD Sbjct 121 ALPQVKPGTVARTVPVGAAGYRTVIWLDSPADAGAAKATFLRWAWYAARREELHLDGADD 180 Query 317 EFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIA 376 +FST +RVE AL TVV LRLS+ +Q+SL AR+VRYG DEIV+ AG VP +TF+++ Sbjct 181 DFSTVQRVEHALDTVVAAALRLSAEEQRSLRSAARIVRYGADEIVEDAGQVPSAMTFLVS 240 Query 377 GSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVV 436 G V+LT T +DG+VV ++TL +G FLGLTALTRQP+ A A ALEEVTAL+I REH+E +V Sbjct 241 GRVQLTATAEDGTVVPVSTLAEGEFLGLTALTRQPNLASAYALEEVTALEIDREHIEHLV 300 Query 437 MNKPMLLQELGRVIDERQRKAQQAIR 462 P LLQ GR+++ER+ K + A R Sbjct 301 TRAPALLQNFGRILEERRSKVRGARR 326 >gi|41408346|ref|NP_961182.1| hypothetical protein MAP2248c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396702|gb|AAS04565.1| hypothetical protein MAP_2248c [Mycobacterium avium subsp. paratuberculosis K-10] Length=331 Score = 442 bits (1136), Expect = 8e-122, Method: Compositional matrix adjust. Identities = 217/326 (67%), Positives = 260/326 (80%), Gaps = 0/326 (0%) Query 137 VRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVVEVNW 196 +R+GGLF ALG+TSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWL+T T GRVVEVNW Sbjct 1 MRIGGLFTALGITSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLDTGTTSGRVVEVNW 60 Query 197 RAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAMLNRAAS 256 R+VHIDTG+G++IMPNSMLATT+F NLSRP G H+ +I TTFST+D PD+VCA L+R A Sbjct 61 RSVHIDTGAGIRIMPNSMLATTSFINLSRPPGPHKVAIDTTFSTADAPDRVCATLSRVAR 120 Query 257 ALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAARREGLHLDEADD 316 ALP VKPG V T+ GAA YRT + L SPAD G +ATFLRW WYAARRE LHLD ADD Sbjct 121 ALPQVKPGTVARTVPVGAAGYRTVIWLDSPADAGAAKATFLRWAWYAARREELHLDGADD 180 Query 317 EFSTAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIA 376 +FST +RVE AL TVV LRLS+ +Q+SL AR+VRYG DEIV+ AG VP +TF+++ Sbjct 181 DFSTVQRVEHALDTVVAAALRLSAEEQRSLRSAARIVRYGADEIVEDAGQVPSAMTFLVS 240 Query 377 GSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVV 436 G V+LT T +DG+VV ++TL +G FLGLTALTRQP+ A A ALEEVTAL+I REH+E + Sbjct 241 GRVQLTATAEDGTVVPVSTLAEGEFLGLTALTRQPNLASAYALEEVTALEIDREHIEHLG 300 Query 437 MNKPMLLQELGRVIDERQRKAQQAIR 462 P LLQ GR+++ER+ K + A R Sbjct 301 TRAPALLQNFGRILEERRSKVRGARR 326 >gi|41407376|ref|NP_960212.1| hypothetical protein MAP1278c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41395728|gb|AAS03595.1| hypothetical protein MAP_1278c [Mycobacterium avium subsp. paratuberculosis K-10] Length=370 Score = 389 bits (998), Expect = 8e-106, Method: Compositional matrix adjust. Identities = 199/298 (67%), Positives = 239/298 (81%), Gaps = 0/298 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 M+ DS+ YWA + +GLP LIV TE H LVR++S LAR LLR+YL+PLGA+L+L Sbjct 1 MSTFDSSSLYWAAAVVLGLPLLLIVFTEWHQSLVRKHSPLARPVFLLRSYLIPLGALLVL 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LV + +PA+ +VRVL TAFGF+V+VLLLS LNAT+F+GAP+ SWR+R+P IF+DV RF Sbjct 61 LVNVARMPAQFTSVRVLATAFGFVVVVLLLSGLNATVFEGAPEGSWRQRVPGIFLDVTRF 120 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 LIG+GLAVI SY+WGVRVGGLF ALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRI D Sbjct 121 VLIGVGLAVIFSYVWGVRVGGLFTALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIGD 180 Query 181 WLETPTARGRVVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 WL+TP ARGR+VE NWR+VHI TG GLQI PNS+LATT+FTNLSRP G H+ ++T TFS Sbjct 181 WLDTPAARGRIVEANWRSVHIQTGRGLQITPNSVLATTSFTNLSRPPGGHQLTLTATFSE 240 Query 241 SDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLR 298 +DPPD+VCA+L R A ALP +P V A ++ G AEY T+ LTSPAD+ QAT LR Sbjct 241 TDPPDRVCALLRRVADALPQRRPDAVAAAVSAGGAEYHVTIGLTSPADDSAAQATLLR 298 >gi|229818727|ref|YP_002880253.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Beutenbergia cavernae DSM 12333] gi|229564640|gb|ACQ78491.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Beutenbergia cavernae DSM 12333] Length=473 Score = 326 bits (836), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 183/443 (42%), Positives = 252/443 (57%), Gaps = 0/443 (0%) Query 20 PAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLLVKASEVPAEDPTVRVLTT 79 P L +LT+ ++L RR S L S LRN ++P + +L+ A+E P + VRVL T Sbjct 18 PLALFLLTQWQDVLRRRGSALLAPVSFLRNAVVPAFGIFVLVRFAAEFPPTNVWVRVLAT 77 Query 80 AFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALIGIGLAVILSYIWGVRV 139 G +LV LS LNA +F A + SWR R+P+IFV++AR L+ +G+AVILS++WG V Sbjct 78 VAGVALLVFALSALNAMMFAQAREGSWRARIPSIFVEIARLVLVVLGMAVILSWVWGADV 137 Query 140 GGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVVEVNWRAV 199 GG+FAALGVT +V+G LQ ++G +VSGL +LFEQPF+I D L A GRVVEVNWR+V Sbjct 138 GGMFAALGVTGIVLGFALQGAIGSVVSGLLLLFEQPFQIGDRLSAAGAVGRVVEVNWRSV 197 Query 200 HIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAMLNRAASALP 259 HI+TG G+ I+PNS L ++F NLS P G + +I F+ DPP V +L A LP Sbjct 198 HIETGEGVHIIPNSSLGGSSFVNLSEPEGRFDVAIDAVFAADDPPATVIGVLRDVARDLP 257 Query 260 HVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAARREGLHLDEADDEFS 319 ++ G P+ Y TT+ L PADE + F W+WYAARR GL LD S Sbjct 258 TLRSGARPSVALTAPHTYTTTLPLHGPADESSATSVFRLWLWYAARRAGLSLDGGSAGPS 317 Query 320 TAERVESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSV 379 + +A V LS + A L YG EI+ HAG V G+ FV+AG V Sbjct 318 AGDEASAAAMAEVQELFGLSDAVVDGARDSAVLRVYGDGEILHHAGAVARGLLFVLAGRV 377 Query 380 RLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVVMNK 439 +L+V+ + A +++G + G L R+P A AL E L + E + + Sbjct 378 QLSVSLGGEARAVEAPIERGGYTGEACLAREPHGFTAHALGETRVLFVPAEVTRAAALAE 437 Query 440 PMLLQELGRVIDERQRKAQQAIR 462 P L Q +G V D R+R ++ R Sbjct 438 PQLAQRIGAVADARRRLVREIAR 460 >gi|339295327|gb|AEJ47438.1| transmembrane protein [Mycobacterium tuberculosis CCDC5079] gi|339298945|gb|AEJ51055.1| transmembrane protein [Mycobacterium tuberculosis CCDC5180] Length=158 Score = 314 bits (805), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 157/158 (99%), Positives = 158/158 (100%), Gaps = 0/158 (0%) Query 324 VESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTV 383 +ESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTV Sbjct 1 MESALRTVVGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTV 60 Query 384 TTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVVMNKPMLL 443 TTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVVMNKPMLL Sbjct 61 TTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAVALEEVTALQIGREHLEQVVMNKPMLL 120 Query 444 QELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPARR 481 QELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPARR Sbjct 121 QELGRVIDERQRKAQQAIRRDLHQSPAAAGEHRGPARR 158 >gi|289758565|ref|ZP_06517943.1| cyclic nucleotide-binding protein [Mycobacterium tuberculosis T85] gi|289714129|gb|EFD78141.1| cyclic nucleotide-binding protein [Mycobacterium tuberculosis T85] Length=129 Score = 259 bits (662), Expect = 8e-67, Method: Compositional matrix adjust. Identities = 128/129 (99%), Positives = 129/129 (100%), Gaps = 0/129 (0%) Query 353 VRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPD 412 +RYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPD Sbjct 1 MRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPD 60 Query 413 PAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAA 472 PAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAA Sbjct 61 PAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQSPAAA 120 Query 473 GEHRGPARR 481 GEHRGPARR Sbjct 121 GEHRGPARR 129 >gi|158334573|ref|YP_001515745.1| mechanosensitive ion channel/cyclic nucleotide-binding domain-containing protein [Acaryochloris marina MBIC11017] gi|158304814|gb|ABW26431.1| mechanosensitive ion channel/cyclic nucleotide-binding domain protein, putative [Acaryochloris marina MBIC11017] Length=483 Score = 235 bits (599), Expect = 1e-59, Method: Compositional matrix adjust. Identities = 154/484 (32%), Positives = 248/484 (52%), Gaps = 34/484 (7%) Query 2 NLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLL 61 +LL +WF W+ G+ +G P ++VL E ++ L +LRN +LP+ ++L Sbjct 4 SLLQQSWFLWSCGLMVGFPCLMLVLNESIVYTQKQGKPLVHTLRILRNLVLPIFVGFIVL 63 Query 62 VKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFA 121 K + E +R++ T+ ++ LS +N LF A +W+ ++P + D+ RF Sbjct 64 TKIVGLDPEQTAIRLVQTSLWVSLIHAALSFVNVLLFVEAGGHTWQAQVPKLLRDLTRFF 123 Query 122 LIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDW 181 LI IG A +LS +W +GGL ALGV+S+VIGL LQ+++G + SG+ +LF +PF I DW Sbjct 124 LILIGTAFVLSLVWKTDLGGLLTALGVSSIVIGLALQDTLGNLFSGIALLFGRPFVIGDW 183 Query 182 LETPTARGRVVEVNWRAVHIDT-GSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 L+ G+V+E+NWRAVH+ T + I+PNS+LA F N RP H + FS Sbjct 184 LKFGDTVGKVIEINWRAVHLITRNKEMLIVPNSVLAKEVFYNYRRPQSLHGEPMELGFSY 243 Query 241 SDPPDKVCAMLNRAASALPHV--KPGVVPATIARGAAEYRTTVRLT-SPADEGP-TQATF 296 DPP+KV ++ +AA P V P + T A G + VRL D P + F Sbjct 244 DDPPNKVKQVIRQAALETPGVLSDPEPIIQTSAYGDSSINYYVRLYLRDYDRVPEIRDAF 303 Query 297 LRWVWYAARREGL----------HLDEADDEFSTA-ERVESALRTVVG--------PELR 337 + VWYAA+R GL H E + R+ + LR++ E Sbjct 304 MTRVWYAAQRHGLTIPFPIRTLIHERPPKPELNGGTNRIITELRSLPCFITTHTEVLEKL 363 Query 338 LSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLK 397 ++++D +S + R++ G +E+ H F++ G V++ V + + L Sbjct 364 VTNADFKSFGKGERIIYQGQEEVNLH---------FLLTGQVQMNVLSQTNHDQEVLRLS 414 Query 398 KGTFLGLTA-LTRQPDPAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRK 456 KG F G TA L+R+P VAL +V + + E ++ ++ P L +E+ +I+ R++ Sbjct 415 KGDFFGATALLSREPSSNSVVALSDVDVMILEIEAMQVLIERTPQLAREMDEIIEARRKA 474 Query 457 AQQA 460 Q A Sbjct 475 IQIA 478 >gi|307151658|ref|YP_003887042.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Cyanothece sp. PCC 7822] gi|306981886|gb|ADN13767.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Cyanothece sp. PCC 7822] Length=485 Score = 234 bits (597), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 156/486 (33%), Positives = 248/486 (52%), Gaps = 26/486 (5%) Query 3 LLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLLV 62 ++ WF W + +G P +++L E L R+ L +LRN ++P A+ LLLV Sbjct 5 IIKQNWFVWTWVLILGFPMLMLLLNEFVVQLERQQKPLVTPVRILRNLVVPTLAIFLLLV 64 Query 63 KASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFAL 122 K ++ E VR++ T ++ +L+L+N LF+ A +SW+ ++P +F+D++RF L Sbjct 65 KVLQLAEEAILVRLIETVLWIFIIYAVLTLINILLFEQARPESWQSQVPKLFLDLSRFFL 124 Query 123 IGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWL 182 I +G A++LS +W +G L ALGV S+VIGL LQ+S+G I SG+ +LFE+P R DW+ Sbjct 125 ILVGTALVLSSVWKTDLGALLTALGVGSLVIGLALQDSLGNIFSGIALLFERPIRSGDWV 184 Query 183 ETPTARGRVVEVNWRAVHIDT-GSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTS 241 E G+V+EV WR+VH+ T L ++PNS LA + F NLSRP G H + FS Sbjct 185 EIGDKVGKVIEVTWRSVHLQTWNRDLLVIPNSELAKSNFRNLSRPTGLHVETFEVGFSYD 244 Query 242 DPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADE-GPTQAT---FL 297 DPP++V +L A V P G ++ ++ D+ G ++ F+ Sbjct 245 DPPNRVKQILKTTARETQGVLSDPEPFVQTTGYKDFYINYKVGLFIDDYGQSRKILDEFI 304 Query 298 RWVWYAARREGLHLD---EADDEFSTAE--------RVESALRTVVGPELRLSSS---DQ 343 +WYAA+R L + + E+ R+ LR++ P L + DQ Sbjct 305 TRIWYAAKRHHLTIPYPIQNQYEYQGVAPIPEDRVLRITEILRSI--PSLSMIDPLLLDQ 362 Query 344 QSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLG 403 L +YG EIV +G+ ++ G V+L V G+ + L +G F G Sbjct 363 --LNDNITTQKYGKGEIVIAQEQRLLGLYIILQGRVQLWVRDRTGNTQPVLELSEGDFFG 420 Query 404 LTA--LTRQPDPAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAI 461 + A L+ ALE++ L + E L+ +++ P ELG +++ R RK QA Sbjct 421 VQASLLSDHQSDVSVEALEDLEVLILDTETLQLLLLRSPRFALELGELMESR-RKLVQAA 479 Query 462 RRDLHQ 467 + L Q Sbjct 480 KSSLFQ 485 >gi|332709913|ref|ZP_08429869.1| small-conductance mechanosensitive channel [Lyngbya majuscula 3L] gi|332351284|gb|EGJ30868.1| small-conductance mechanosensitive channel [Lyngbya majuscula 3L] Length=501 Score = 233 bits (594), Expect = 5e-59, Method: Compositional matrix adjust. Identities = 142/486 (30%), Positives = 249/486 (52%), Gaps = 18/486 (3%) Query 6 STWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLLVKAS 65 + WF WA+ + IG P +I+LTE+ + L RR +A L+RN +LP+ LL + Sbjct 8 NDWFIWAIALGIGFPLLVIILTEITHRLQRRGQPIAVTLRLVRNRVLPVLVFLLFIQNVV 67 Query 66 EVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALIGI 125 E+ ++ V+++ T V+ LSL+N+ LF+ A + +WR R+P + +D++RF L+ + Sbjct 68 ELDLDNNVVKLVETLLWIFVIDASLSLINSVLFEAAGENTWRGRIPKLLLDLSRFFLVAL 127 Query 126 GLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETP 185 G A++LS +WG + GL ALGV S+VIGL LQ+S+G + SG+ +LF +PF + DWL+ Sbjct 128 GAAIVLSKVWGADLAGLATALGVGSIVIGLALQDSLGSVFSGVALLFARPFEVGDWLQIG 187 Query 186 TARGRVVEVNWRAVHIDTGSG-LQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPP 244 G+V+++NWRAVH+ T G + I+P+ +L N S+P H + F + DPP Sbjct 188 DKVGQVIDMNWRAVHLVTRDGDMIIIPHRVLGGEIVLNYSKPKPIHVETFRIDFDSDDPP 247 Query 245 DKVCAMLNRAASA----LPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWV 300 + + +L A A L P + Y + D + + + Sbjct 248 NLIKQVLKETALATEGILSDPSPEIRTMEYNDYRGNYEVKFSIEDYKDAPRIREQLMTRI 307 Query 301 WYAARREGL----------HLD-EADDEFSTAERVESALRTV-VGPELRLSSSDQQSLAR 348 WYAA+R L LD + + ST + +L+++ V + + ++L++ Sbjct 308 WYAAQRNNLGPTIPIYRLRKLDSDPNQADSTLTKFTESLKSMPVFVPVAKQQKNLENLSK 367 Query 349 YARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTAL- 407 A L +G E V G + +IAG L + G + TL G F G AL Sbjct 368 GAVLQHFGVGETVIRQGDPGHALYIIIAGKAVLNLKDSYGEQQEVMTLSSGEFFGEMALF 427 Query 408 TRQPDPAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRDLHQ 467 + +P +E++ + + + + Q++ + P L +E+G++I+ R++ + + +L Sbjct 428 SGKPSSVSVTVVEDLQTIALYSDLVNQMIESTPSLAREIGQIIEARRKAIDEVKQANLAS 487 Query 468 SPAAAG 473 S A++ Sbjct 488 SLASSN 493 >gi|254422992|ref|ZP_05036710.1| transporter, MscS family [Synechococcus sp. PCC 7335] gi|196190481|gb|EDX85445.1| transporter, MscS family [Synechococcus sp. PCC 7335] Length=492 Score = 227 bits (579), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 152/481 (32%), Positives = 251/481 (53%), Gaps = 25/481 (5%) Query 1 MNL-LDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLL 59 MN+ L W W + + +G P ++++ EL L + N + + A LR ++ PL A+ Sbjct 1 MNVSLADDWLRWGLILMLGFPTLMLLVGELVLQLDKLNHPMVKVAKELRTFVFPLSALFF 60 Query 60 LLVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVAR 119 LL + E+ ++ ++++ T ++ LS N LF GA SW+ +P +F D+ R Sbjct 61 LLTRVLELSSDWVVIKIIETLAWVALIAAALSFANVLLFTGAKPHSWQAEMPKLFRDLVR 120 Query 120 FALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRID 179 LI +G A++L ++G +GGL ALG+ VV+G LQ+++G ++SG+ +LFE+PF++ Sbjct 121 VFLIALGAALVLREVFGQDLGGLITALGLGGVVLGFALQDTLGNLISGMALLFERPFQVG 180 Query 180 DWLETPTARGRVVEVNWRAVHIDTGS-GLQIMPNSMLATTAFTNLSRPAGAHECSITTTF 238 DWLE G+V+EVNWR+VHI T + ++PNS+L+ N + P H + F Sbjct 181 DWLEIDGNTGKVIEVNWRSVHIVTRELEMLVVPNSVLSQAVIRNYNGPQPRHIEPVDIGF 240 Query 239 STSDPPDKVCAMLNRAASALPHV--KPGVVPATIARG--AAEYRTTVRLTSPADEGPTQA 294 S SDPP+KV ++ A V +P V TI+ + YR + L + A + Sbjct 241 SYSDPPNKVKQVMLETALGTDGVLKQPAPVVHTISYDDFSITYRVRLFLANYALVPTIRD 300 Query 295 TFLRWVWYAARREGL-----------HLDEADDEFSTAERVESALRTVVGPELRL-SSSD 342 F+ +WYAA+R GL H E T +R+ ++++ P L + S Sbjct 301 EFVTRIWYAAQRNGLSIPFPIRDVYHHHVPKVTEGETLQRLAYYMKSL--PSLAIVEDSV 358 Query 343 QQSLARYARLVRYGTDE--IVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGT 400 +++A A +G E IVQH V + FV+AG G IA L +G Sbjct 359 LEAIAAQASFRHFGKGESPIVQHQQEVKL--HFVLAGEAIAFCQDAKGKKYTIAELTRGD 416 Query 401 FLGLTA-LTRQPDPAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQ 459 F G +A L +P P A +++ L + E +++++ P+ Q+LG VI++RQRK ++ Sbjct 417 FFGYSAVLANEPSPMTITATKDLEVLILEIEAVQKMLNQTPLFAQQLGAVIEDRQRKLKE 476 Query 460 A 460 A Sbjct 477 A 477 >gi|126660522|ref|ZP_01731629.1| probable conserved transmembrane protein [Cyanothece sp. CCY0110] gi|126618222|gb|EAZ88984.1| probable conserved transmembrane protein [Cyanothece sp. CCY0110] Length=416 Score = 192 bits (488), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 125/420 (30%), Positives = 209/420 (50%), Gaps = 27/420 (6%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 + L++ WF WA+ + +G P +I+L E+ L + L + RN + PL A+LL Sbjct 3 ITLVEQNWFRWAILLILGFPLVMILLNEVIVRLRQEEKPLVATIIIFRNLVFPLVALLLF 62 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 L + E+P E +R + T ++ +LS +F A SW++R+P + +D+ RF Sbjct 63 LTRVLEIPEETTIIRSVKTLVWIGMIHAILSAFKVVIFDQAVAGSWQERVPDLLLDLIRF 122 Query 121 ALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDD 180 L+ AVILS +W + +G L A GV S+VIGL LQ+++ + SG+ +LFE+PF + D Sbjct 123 FLVACITAVILSTVWKIDLGALLTAFGVGSLVIGLALQDTLKNLFSGILLLFERPFALGD 182 Query 181 WLETPTARGRVVEVNWRAVHIDT-GSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFS 239 WL+ G+V++VNWR+V++ T ++PNS+LA FTN +RP H FS Sbjct 183 WLQVGDTIGKVIKVNWRSVYLQTRDRDSVVIPNSILAQGNFTNYNRPTPLHVERFLFGFS 242 Query 240 TSDPPDKVCAMLNRAASALPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPT----QAT 295 DPP+KV +L A + P + P A++ T ++ D T + Sbjct 243 YDDPPNKVIQVLTETALSTPGILRDPSPWVRVENYADFSITYQIGLFVDNYETMLKIRND 302 Query 296 FLRWVWYAARREGL----------HLDEAD-DEFSTAERVESALRTV-----VGPELRLS 339 F+ +WYAA+R L H+D A + + ++V +R++ + E + Sbjct 303 FVIRIWYAAKRYHLTIPYPIQTEYHMDLATMPKPNPTQQVTDMMRSLPNFGNMAAERFIE 362 Query 340 SSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKG 399 D ++ YA+ E V G +G+ ++ G + V ++ IA L +G Sbjct 363 EKDASNIRYYAQ------GEWVFQEGERILGLYLILNGHAVILVRDNNEQNQEIARLGQG 416 >gi|220906966|ref|YP_002482277.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Cyanothece sp. PCC 7425] gi|219863577|gb|ACL43916.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Cyanothece sp. PCC 7425] Length=479 Score = 169 bits (427), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 137/470 (30%), Positives = 221/470 (48%), Gaps = 22/470 (4%) Query 12 AVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLLVKASEVPAED 71 + I +GLP +I L EL R ++ + +++RN L P A+ LLL + +V + Sbjct 13 GLAIILGLPLLVIGLGELIERSKREHNPFTQVLTVIRNLLFPPLALWLLLRQFFQVAEDG 72 Query 72 PTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALIGIG-LAVI 130 +RV+ + F ++ LLL LN TL G Q+SW+ LP + + R AL+ +G LA + Sbjct 73 IALRVVGSLFWVALIYLLLLFLNTTLTAGKQQKSWQLHLPNLLFQLLR-ALVVLGILAYV 131 Query 131 LSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGR 190 L IW V + + ALG+ S+VI L LQ+++ +VSG ++ E PF++ DW++ G Sbjct 132 LGNIWQVDLTKIMGALGIGSLVIALALQDTLSNLVSGFLLIIESPFKVGDWIKVGELEGE 191 Query 191 VVEVNWRAVHIDT-GSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCA 249 V+E+NWRAV I T + I+PN L N + H + S + PD+V Sbjct 192 VIEINWRAVRIKTLDKDIIIIPNGNLGKENICNYTLHDPLHVVRMYMPISYEEHPDRVIQ 251 Query 250 MLNRAASAL----PHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAAR 305 +L A ++ P P + P EY +T + + F R +YA Sbjct 252 VLQDVALSVDGIEPQPLPDIDPQAYKNSYIEYEIRFCITDYSRLEEIKGDFFRRAYYAIH 311 Query 306 REGLHLDEAD-----------DEFSTAERVESALRTVVGPEL-RLSSSDQQSLARYARLV 353 R H+ D D TAER+ LR++ P RL S L ++A L Sbjct 312 RNQFHIPFPDKVEYRVFNLPQDPEDTAERLTEILRSL--PLFSRLDSRTLLELKQHATLE 369 Query 354 RYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLG-LTALTRQPD 412 R+ E + AG + +++G V L++ G IA L +G FLG + L + Sbjct 370 RFAVGERIIDAGTLDQAFYILLSGQVMLSLVGLMGEEQEIAHLTEGDFLGEMVFLPGETS 429 Query 413 PAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIR 462 P A E ++I + ++ + P E+ + I+ER++ + A R Sbjct 430 PVYATVTETAKVIRIAPVAIVHLIQHHPKFAVEMSQFIEERKKWIRLAHR 479 >gi|254425845|ref|ZP_05039562.1| transporter, MscS family [Synechococcus sp. PCC 7335] gi|196188268|gb|EDX83233.1| transporter, MscS family [Synechococcus sp. PCC 7335] Length=491 Score = 159 bits (402), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 131/463 (29%), Positives = 218/463 (48%), Gaps = 16/463 (3%) Query 14 GIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLLVKASEVPAEDPT 73 G+ +G+P I L+E+ L RR LA RN LPL + +L+L ++ A Sbjct 11 GLIVGIPLAAIALSEIIERLRRRKVPLADALRGFRNVTLPLLSAVLILQYVFQLTANSQP 70 Query 74 VRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALIGIGLAVILSY 133 +RVL TA L+ L LL+ + + + ++P++++ R ++ + IL+ Sbjct 71 LRVLQTALWLSFLINGLHLLSTLFTPSSRRIKGKIQVPSLYLMAGRILVVVLCAIYILAN 130 Query 134 IWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVVE 193 IW + + + +ALGV S+V+ L LQ+++ +VSG +L ++PF DWL+ V+E Sbjct 131 IWQIDLARITSALGVGSLVVALALQDTLSNLVSGFLLLLDRPFNEGDWLQLGDVEAEVLE 190 Query 194 VNWRAVHI-DTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAMLN 252 VNWR+V + + + I+PN L N + AH +IT FS DPP+ V +L Sbjct 191 VNWRSVRLRNRDRDIIIIPNGELGKATICNYTLLDLAHAETITVGFSYDDPPNVVKPVLL 250 Query 253 RAASALP--HVKPGVVPATIARG--AAEYRTTVRLTSPADEGPTQATFLRWVWYAARREG 308 +A +A P V + G + +Y LT + + ++Y ARR+G Sbjct 251 KAVAATEGAMASPAPVVRVVNYGDFSVDYNVKFFLTDYQGKDDIASELRSHIYYMARRQG 310 Query 309 LHLD-----EADDE---FSTAERVESALRTVVGPELRLS-SSDQQS-LARYARLVRYGTD 358 L + E E + E VE L + G S S DQ S LA+ + L YG Sbjct 311 LTIPYPIALEYQLEGAALAPPETVEPILNILKGLTYFSSISPDQLSQLAQESELETYGRG 370 Query 359 EIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTR-QPDPAGAV 417 E + AG + G + GSV L+ +D G + L+ G G L R +P Sbjct 371 EQIVAAGDLAPGFFIIQYGSVSLSAMSDQGESQEVTRLQAGDCFGERVLLRTEPSLVTVS 430 Query 418 ALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQA 460 +E++ A++I + + +++ ++IDER R+ + A Sbjct 431 VVEDLKAVRISPWMMANIAERNAKFARDINQLIDERVREVRIA 473 >gi|41408347|ref|NP_961183.1| hypothetical protein MAP2249c [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396703|gb|AAS04566.1| hypothetical protein MAP_2249c [Mycobacterium avium subsp. paratuberculosis K-10] gi|336458215|gb|EGO37196.1| hypothetical protein MAPs_15100 [Mycobacterium avium subsp. paratuberculosis S397] Length=154 Score = 153 bits (387), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 95/135 (71%), Positives = 112/135 (83%), Gaps = 0/135 (0%) Query 1 MNLLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLL 60 MN S+WFYWA+GIAIGLP G+I LTE+H+ L+RR S LARQ LLRNYLLPLGA+LL Sbjct 1 MNAFGSSWFYWAIGIAIGLPIGMIALTEIHDALLRRQSPLARQVGLLRNYLLPLGALLLF 60 Query 61 LVKASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARF 120 LV+AS +PA VR+LTTAFG LVLVLLLS LNAT+F+ AP++SWRKRLP IF+DVAR Sbjct 61 LVQASGIPAGHIPVRILTTAFGLLVLVLLLSGLNATVFERAPEKSWRKRLPTIFIDVARL 120 Query 121 ALIGIGLAVILSYIW 135 ALI +GLAV+ SYIW Sbjct 121 ALICVGLAVMSSYIW 135 >gi|158425588|ref|YP_001526880.1| integral membrane protein [Azorhizobium caulinodans ORS 571] gi|158332477|dbj|BAF89962.1| putative integral membrane protein [Azorhizobium caulinodans ORS 571] Length=473 Score = 139 bits (351), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 116/457 (26%), Positives = 215/457 (48%), Gaps = 25/457 (5%) Query 11 WAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLLVKASEVPAE 70 W + I +G P ++L EL +S R L+ ++P GAV +++ + +P E Sbjct 12 WTILIVLGFPLLTVLLIELTRRFAGPDSAARRPIKALQMIVVPAGAVWIIVHELLHLPPE 71 Query 71 DPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALIGIGLAVI 130 TV+++ TA G L+L + ++L +L + R P +F ++ A++ IG A+I Sbjct 72 GLTVKIVDTAVGILLLHAVFTILQ-SLIIAFSETVGRLPAPRLFYELGSSAVVAIGAAII 130 Query 131 LSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGR 190 +S IW V +G L ALG+ SVV+GL LQN +G +V+G+ + + F + DWL+ + Sbjct 131 VSTIWDVDLGSLLGALGIGSVVLGLALQNVIGGLVAGVIVFSGRHFNLGDWLQIDGTPAK 190 Query 191 VVEVNWRAVHIDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAM 250 VV+++WRA+ ++T SG +I+ S ++A ++R + + + P + A+ Sbjct 191 VVQIDWRAITVETLSGERIVVPSANMSSASLRITRARQSVSVATDVSLPPGTAPAEAKAL 250 Query 251 LNRAASALPHVKPGVVPAT----IARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAARR 306 L AA +P + A + A Y + + + + FL +WY +R Sbjct 251 LLEAARDVPQLLDANAVACRVKQLGGTAIVYGVSFPVADASQVVKARDAFLHRLWYVGQR 310 Query 307 EGLHLDE--ADDEFSTAERVESALRTVVGP-ELRLSSSDQQSLARYARLVRYGTDEIVQH 363 G+ + E + +E + ++ L + G S D + +A ARL Y EI+ Sbjct 311 HGVSVAEGVSAEELYGTDTPQTRLAALAGTGAFGAVSDDLRVVAVDARLRLYAAGEIILR 370 Query 364 AGVVPMGITFVIAGSVRLTVTTD-------DGSVVAIATLKKGTFLGLTALTRQPDPAGA 416 AG +++G+ R+++ DG++ A +GT P Sbjct 371 AGEAAPYFLVLLSGAARVSLPAGGVVERLADGALYATRDAFRGT----------PSSVEV 420 Query 417 VALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDER 453 +A EV L++ +E+++ P L Q + +++ R Sbjct 421 LAESEVHLLEVPVTAMERLLERHPALAQRVDMIVEAR 457 >gi|67925546|ref|ZP_00518878.1| hypothetical protein CwatDRAFT_0633 [Crocosphaera watsonii WH 8501] gi|67852603|gb|EAM48030.1| hypothetical protein CwatDRAFT_0633 [Crocosphaera watsonii WH 8501] Length=209 Score = 127 bits (319), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 66/191 (35%), Positives = 110/191 (58%), Gaps = 0/191 (0%) Query 3 LLDSTWFYWAVGIAIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLLV 62 L++ WF WA+ + +G P +I+L E+ L + L + RN + PL A+L L Sbjct 19 LVEQNWFRWAISLILGFPLIMIILNEIIVRLRQEEKPLIATIIIFRNLVFPLVALLFLFT 78 Query 63 KASEVPAEDPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFAL 122 + E+P E +R++ T ++ +LS +F A SW++R+P + +D+ RF L Sbjct 79 RVLEIPEETTIIRLVKTLVWIGMIHAMLSAFKVLIFDQAVSGSWQERVPDVLLDLIRFFL 138 Query 123 IGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWL 182 + AVILS +W + +G L A GV S+VIGL LQ+++ + SG+ +LFE+PF + DWL Sbjct 139 VACITAVILSTVWKIDLGALLTAFGVGSLVIGLALQDTLKNLFSGILLLFERPFALGDWL 198 Query 183 ETPTARGRVVE 193 + G+V++ Sbjct 199 QVGETIGKVIK 209 >gi|300864235|ref|ZP_07109118.1| putative Cyclic nucleotide-regulated small mechanosensitive ion channel [Oscillatoria sp. PCC 6506] gi|300337772|emb|CBN54264.1| putative Cyclic nucleotide-regulated small mechanosensitive ion channel [Oscillatoria sp. PCC 6506] Length=503 Score = 127 bits (319), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 128/470 (28%), Positives = 213/470 (46%), Gaps = 24/470 (5%) Query 12 AVGIAIGLPAGLIVLTELHNILV-RRNSHLARQASLLRNYLLPLGAVLLLLVKASEVPAE 70 A+ +G P +++L E+ + L R N L R + LR+++ P A+ L++ + P Sbjct 8 ALIFILGFPLLIVILGEVISRLEPRGNIRLVRFLNSLRSFVFPCLAIWLVMNQFLGFPHN 67 Query 71 DPTVRVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWR-KRLPAIFVDVARFALIGIGLAV 129 +R+L T V+ + LL L SW ++P +F+ + R L +G+ Sbjct 68 SIFLRLLETLILLGVIFAGILLLGILLTTEQNPTSWHLFKVPRLFLQIIR-ILFFLGITT 126 Query 130 -ILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTAR 188 ILS +W V + + AALGV SVVI L LQ ++ +VSG +LF+ PF++ DW+ Sbjct 127 YILSSLWQVDLSNIAAALGVGSVVIALALQTTLSNLVSGFLLLFDSPFKVGDWIRFGDIE 186 Query 189 GRVVEVNWRAVHIDT-GSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKV 247 G+VV++NWR+V + T L I+PN +L N H FS D P+ V Sbjct 187 GQVVDLNWRSVRLRTLNRELLIVPNGVLDQQNIFNYHSGDRVHGERFKIGFSYDDSPNFV 246 Query 248 CAMLNRAASA----LPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYA 303 A++ AA A L P V + A Y + + + F ++YA Sbjct 247 QAVIKSAAIATKGILSDPAPDVFTMSYDDFAITYEVKYFIDDFQNVEEIRNDFRTRIFYA 306 Query 304 ARREGLHL-----DEADDEFSTAERVESALRTVVGPE-------LRLSSSDQQSLARYAR 351 A+R GL + T +R E + + L L + + LA A Sbjct 307 AKRNGLTIPFPIRTLQHVRIRTPQREERVQEIAIFLQSLPFFAFLELEAIAK--LADVAI 364 Query 352 LVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALT-RQ 410 L YG + V G+ G + +G+++L VT GS + L + F G TAL + Sbjct 365 LQFYGLGDEVISEGIPDPGFYIIESGAIKLLVTDLSGSQQEVIHLSREDFFGETALLPGE 424 Query 411 PDPAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQA 460 V +++T L RE + ++ +++ + I+ER+++ +QA Sbjct 425 NSQVTGVVTQDLTVLVFEREAIATLMAGSARFARQINQFIEERKKRIEQA 474 >gi|300866764|ref|ZP_07111446.1| putative Cyclic nucleotide-regulated small mechanosensitive ion channel [Oscillatoria sp. PCC 6506] gi|300335270|emb|CBN56606.1| putative Cyclic nucleotide-regulated small mechanosensitive ion channel [Oscillatoria sp. PCC 6506] Length=479 Score = 123 bits (308), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 114/437 (27%), Positives = 194/437 (45%), Gaps = 9/437 (2%) Query 24 IVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLLLLVKASEVPAEDPTVRVLTTAFGF 83 I+L E + L R++ LA +R Y+LP AV+L++ + + ++ R L T Sbjct 21 ILLGEAVSRLERQHHPLAIGLRQVREYVLPPLAVILVIRQVLRIGDQNSWARFLETLTWV 80 Query 84 LVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVAR-FALIGIGLAVILSYIWGVRVGGL 142 V+V LSL+NA L + +P +F +AR ++ IG +I + +W + + G Sbjct 81 AVIVAGLSLINALLTTKKQPIKGQIHVPNLFFQIARGLVILAIGYHII-NGVWEISLTGF 139 Query 143 FAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVVEVNWRAVHID 202 A+G+ S VI L LQ+++ +VSGL +LF +PFR DW+E +GRV+E NW +V I Sbjct 140 SEAVGLASAVIALALQDTLSNLVSGLLLLFAKPFRAGDWIEIDEKQGRVLEQNWWSVTIV 199 Query 203 TGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAMLNRAASALPHV- 261 T +PN +L+ + N + GA +I+ +FS D P+KV LN + + Sbjct 200 TSEWKLNIPNGVLSQASIINYGQ--GAIWKNISASFSYDDSPNKVMTALNSLIEGIDAIE 257 Query 262 -KPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAARREGLHLDEADDEFST 320 K V ++ Y + ++ P + ++Y +R G L E + Sbjct 258 DKGSAVVSSYEDDRIIYNLSYKIL-PEQDANVSGQLKSRLYYLTKRYGFTLPYPMKEECS 316 Query 321 AERVESALRTVVGPELRLSSSDQ-QSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSV 379 + E A P + Q LA YG E++ G G + G Sbjct 317 LDLQELATYLQSLPYFSTLNDHQINKLAESVTFKAYGNGELIIQEGKEDEGFYIMFKGRG 376 Query 380 RLTVTTDDGSVVAIATLKKGTFLGLTAL-TRQPDPAGAVALEEVTALQIGREHLEQVVMN 438 + G + L+ G A+ + P VA E+V + I + + Q + + Sbjct 377 HAYFKDEKGERQTVDKLELNQAFGEMAIFPGEVSPVTTVADEDVEVVVIPADAIVQAIES 436 Query 439 KPMLLQELGRVIDERQR 455 E+ + I+ER++ Sbjct 437 NNKFASEILQYIEERKK 453 >gi|159899231|ref|YP_001545478.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Herpetosiphon aurantiacus DSM 785] gi|159892270|gb|ABX05350.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Herpetosiphon aurantiacus DSM 785] Length=507 Score = 120 bits (301), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 99/429 (24%), Positives = 187/429 (44%), Gaps = 22/429 (5%) Query 75 RVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALIGIGLAVILSYI 134 ++L T ++ ++L + + L + +P + D+AR ++ + L + + + Sbjct 69 KILQTTVTVSIIAVVLHIGDQLLVRRLAADGRPNAIPRLMRDIARGFVLLMTLLICIGHF 128 Query 135 WGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDW--LETPTARGRVV 192 + V++G + + V + V+GL LQ+ + +++G+ + E+PF DW ++ T GRV+ Sbjct 129 FKVQIGTVLLSSTVFTAVVGLALQDLLKNVIAGIALQMERPFMPGDWIFIDVQTGYGRVL 188 Query 193 EVNWRAVHIDTGSG-LQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAML 251 E++WRA+ + G + ++PN+++A N+S + T PP V +L Sbjct 189 EMSWRAIRVKPRDGQVVVIPNTIIAQQQIINMSATGLPVAMRVAVTVDCVHPPMMVRELL 248 Query 252 NRAASALPHVKPGVVPATIARGAAEYRTTVRLT---SPADEGPT-QATFLRWVWYAARRE 307 A + V P R + TT + S D+ P Q L +WY +R+ Sbjct 249 KEAVLSSRGVVAQPEPFVFVRNYTAFSTTYEVKCWISNYDDFPQLQGDALSRIWYVFQRQ 308 Query 308 GLHLDEADDEFSTAERVESALRTVVGPE-----LR-------LSSSDQQSLARYARLVRY 355 G+H + + E+ R PE LR L + + L+ + + + Sbjct 309 GIHFASNEMVLTRPEQASRQRRLDYTPEQIFDRLRRIKLLDGLHEQELRFLSEHVEIRLF 368 Query 356 GTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTA-LTRQPDPA 414 EI+ H G + + G VR+ V DD + ++ L G G L +P A Sbjct 369 ERGEILAHQGRHEHILYAITRGKVRVEVAHDDQPAIVVSHLGAGDVFGERGMLMDEPRSA 428 Query 415 GAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAI--RRDLHQSPAAA 472 +A E+ + I R L + P L + LG ++ ERQ+ + +R ++Q+P + Sbjct 429 SVIAEEDTRTIVIERHDLAPLYAKNPSLAERLGVMVAERQQATHNYLEQQRSVNQNPTPS 488 Query 473 GEHRGPARR 481 R R Sbjct 489 PAARSITER 497 >gi|182678163|ref|YP_001832309.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Beijerinckia indica subsp. indica ATCC 9039] gi|182634046|gb|ACB94820.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Beijerinckia indica subsp. indica ATCC 9039] Length=505 Score = 114 bits (284), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 96/359 (27%), Positives = 165/359 (46%), Gaps = 21/359 (5%) Query 121 ALIGIGLAV-ILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRID 179 LI +G+A+ I++ ++G VG L A GV ++++GL LQN++ + SG+ + QP+ I Sbjct 120 GLIYVGVALSIVTNVFGFPVGTLIATSGVVAIILGLALQNTLSDLFSGVALNLGQPYGIG 179 Query 180 DWL-ETPTARGRVVEVNWRAVHIDTGSG-LQIMPNSMLATTAFTNLSRPAGAHECSITTT 237 DW+ + GRVVE NWRA H+ G+ L I+PNS LA N+S P +H + Sbjct 180 DWIVVSDVIEGRVVETNWRATHLLNGANDLVILPNSNLAKANLINMSSPDRSHGVKFSVR 239 Query 238 FSTSDPPDKVCAMLNRAASALPHVK---PGVVPATIARGAAEYRTTVRLTSPADEGPTQA 294 + + P + M + S+ ++ P ++ ++ A E + R+ G + Sbjct 240 LAPTRPAFIIEVMRDVLLSSTKILRTPAPTLLIKSLDAQAIEIEFSFRVMDLGGVGAAKN 299 Query 295 TFLRWVWYAARREGLHLDEAD-DEFSTAERVESALR---TVVGPE---------LRLSSS 341 ++ A+ GL L D E S+A ++ GP L+ Sbjct 300 ELFDLIYRHAKAAGLSLAPYDGSEPSSATSTTGDMKQPGNYYGPSRLLAALPLFASLTEE 359 Query 342 DQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTF 401 ++++LA Y DEIV GVV + V G++ + +D + + L G Sbjct 360 EREALAETVSSRTYHKDEIVVEQGVVQNSLVIVRRGALVVNRMEEDRK-IELGRLAPGDC 418 Query 402 LGLTALTRQPDPAGAV-ALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQ 459 G +L G V AL V +I +E L ++ ++P + +ELG ++ R + Q Sbjct 419 FGEASLLAGTGSPGTVQALTFVMVYEIAKEALMPLMQDRPAIAEELGLILSRRVQNEQH 477 >gi|196230474|ref|ZP_03129336.1| MscS Mechanosensitive ion channel [Chthoniobacter flavus Ellin428] gi|196225404|gb|EDY19912.1| MscS Mechanosensitive ion channel [Chthoniobacter flavus Ellin428] Length=503 Score = 111 bits (277), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 112/463 (25%), Positives = 203/463 (44%), Gaps = 27/463 (5%) Query 16 AIGLPAGLIVLTELHNILVRRNSHLARQASLLRNYLLPLGAVLL-LLVKASEVPAEDPTV 74 A+ +PA + L L RR Q LL + A+ L + + ++ +P + Sbjct 15 AVAIPALFAITLGLGRFLKRRA---GVQLGLLYQLFCIVFAIWLPMEIVGTDFSNREPIM 71 Query 75 RVLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALIGIGLAVILSYI 134 VL A L + +L+LL ++ ++ + + P + L I L V++ + Sbjct 72 HVLRAANVLLGTIFILALLRRYYWELWFEKHQQGKAPKFISQLFGLILFIIALFVVIGGV 131 Query 135 WGVRVGGLFAALGVTSVV--IGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVV 192 +G + G A G T VV +G +Q+ +G I++G+ + +PF+ DWL+ V+ Sbjct 132 YGYPIQG--AVFGSTVVVGIVGFAMQDLLGNIIAGIALEIGKPFKTGDWLKIDQQYAEVI 189 Query 193 EVNWRAVHIDTGSGLQI---MPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCA 249 A+ G+ I +PN +A + NL+ P H + F P+ V Sbjct 190 G-GQLALLRGCGTNDDIYLDIPNKAIAGGSIINLTYPTRQHAVRLNVGFDYGTAPNFVKD 248 Query 250 MLNRAASA----LPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAAR 305 +++RAA++ LP P V A A Y + + A +WYAA+ Sbjct 249 IISRAAASVHGVLPSPPPKVYLKDFADSAVHYEIKLWIDDQAMYNDIMDGVRTNIWYAAQ 308 Query 306 REGLHLD------EADDEFSTAERVESALRTVV--GPELR-LSSSDQQSLARYARLVRYG 356 R G+ + + + + A+ V S R V P L+ L Q+ L +A+ +RYG Sbjct 309 RHGIKIPYPIRTVQIERVTAGAKDVMSIARACVRKQPFLQLLDEGQQEKLLGHAKYLRYG 368 Query 357 TDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLG-LTALTRQPDPAG 415 E V G + ++ G + V +G+ +ATL+ G + G ++ LT P A Sbjct 369 RREKVIIQGASGASMFILLHGEAHVYVQA-NGTETRVATLQTGDYCGEMSLLTGDPRSAT 427 Query 416 AVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQ 458 VA + +IG+E L +++ L+Q+L ++ +R+ + + Sbjct 428 VVAATDCEMWEIGKEVLAEILQQNETLVQKLSELLAQRRLETE 470 >gi|241205479|ref|YP_002976575.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Rhizobium leguminosarum bv. trifolii WSM1325] gi|240859369|gb|ACS57036.1| cyclic nucleotide-regulated small mechanosensitive ion channel [Rhizobium leguminosarum bv. trifolii WSM1325] Length=493 Score = 110 bits (275), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 112/397 (29%), Positives = 184/397 (47%), Gaps = 42/397 (10%) Query 81 FGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALIGIGLAVILSYIWGVRVG 140 GF+ L L+L +G+P+++ + L + + V IG+ L+V L++++GV +G Sbjct 90 IGFIRLYLVL--------EGSPREA--RLLQDLVIGVV---YIGMALSV-LAFVFGVPIG 135 Query 141 GLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDW-LETPTARGRVVEVNWRAV 199 L A GV ++++GL LQN++ + SG+ + +P+ I DW L + GRVVE NWRA Sbjct 136 TLVATSGVVAIILGLALQNTLADVFSGIALTLGRPYIIGDWILLSDGTEGRVVESNWRAT 195 Query 200 HIDT-GSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFSTSDPPDKVCAMLNRAASAL 258 HI T G+ + ++PNS LA TN+SRP +H +T + + P V ++ A ++ Sbjct 196 HILTSGNNVVVLPNSFLAKLGLTNVSRPDESHLLILTIRIAPTRMPASVRHVMATALASC 255 Query 259 PHVKPGVVPATIARG----AAEYRTTVRLTSPADEGPTQATFLRWVWYAARREGLHL--- 311 + P +G A E R+TSP+ P + L V+ + GL L Sbjct 256 NSIVREPPPVVALKGLDATALEVELQFRVTSPSQRVPARNEVLDLVYRHCKSAGLLLAIP 315 Query 312 --------DEADDEFSTAERVES-ALRTVVGPELRLSSSDQQSLAR--YARLVRYGTDEI 360 D +E + V AL + L+S +++ LA R R G D I Sbjct 316 PSATVLTADLPTEESAKPPSVTPLALIEAIPVFTTLTSDEKRRLAETTTVREFRKG-DVI 374 Query 361 VQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALTRQPDPAGAV-AL 419 VQ ++P + V AG + ++ L G F G T L + AL Sbjct 375 VQEDEMLP-SLMMVRAGIIAARNAGEE-----CGRLAPGDFFGETGLLAGMQEVCTLEAL 428 Query 420 EEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRK 456 VTA +I +E ++ +P L +E+ + R + Sbjct 429 TPVTAYEIDQEAFAPLLSERPALAEEIADHLASRAER 465 >gi|115376585|ref|ZP_01463816.1| transporter, small conductance mechanosensitive ion channel (MscS) family [Stigmatella aurantiaca DW4/3-1] gi|310822493|ref|YP_003954851.1| mechanosensitive ion channel/cyclic nucleotide-binding domain-containing protein [Stigmatella aurantiaca DW4/3-1] gi|115366390|gb|EAU65394.1| transporter, small conductance mechanosensitive ion channel (MscS) family [Stigmatella aurantiaca DW4/3-1] gi|309395565|gb|ADO73024.1| Mechanosensitive ion channel/cyclic nucleotide-binding domain protein [Stigmatella aurantiaca DW4/3-1] Length=502 Score = 110 bits (275), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 105/366 (29%), Positives = 161/366 (44%), Gaps = 32/366 (8%) Query 111 PAIFVDVARFALIGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFM 170 P I DV F L G+ IL + +GGL A V SVVIGL LQ ++G + +GL + Sbjct 112 PKILRDVIDFTLYGLAALPILQSQLDLNLGGLLATSAVLSVVIGLALQETLGNLFAGLSL 171 Query 171 LFEQPFRIDDWLETPTARGRVVEVNWRAVHIDTGSGLQI-MPNSMLATTAFTNLSRPAGA 229 E+P+++ D++ GRVV++ WRA I T + +PNSM+A N S Sbjct 172 QLERPYQVGDFIRIGEHSGRVVQIGWRATRISTFRCESVTLPNSMVAKEVVRNFSYGYVP 231 Query 230 HECSITTTFSTSDPPDKVCAMLNRAASALPHVKPGVVPA--TIARGAAEYRTTVRL---- 283 I S PP+ V A + +P + VP T A + R +R Sbjct 232 IGVDIFIGLSRDTPPNTVKAAVLDVLDEIPLILKTPVPQCRTWAYDGSSIRYQIRYWVSD 291 Query 284 TSPADEGPTQATFLRWVWYAARREGL---------HLDEADDEFSTA-ERVESALRTV-- 331 S AD Q +WY RRE + HL + D + E V L+ V Sbjct 292 FSQADNAMEQ--IYTQLWYRLRRERIEIPYPQQTVHLRQGMDHAEVSQETVRDLLKAVDL 349 Query 332 --VGPELRLSSSDQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGS 389 V + L Q +AR R+G E + G G TF + S ++V T Sbjct 350 FSVLDDSELHQVHQDLVAR-----RFGKGETIIQEG--DAGHTFYLVASGEVSVRTGKAQ 402 Query 390 VVAIATLKKGTFLG-LTALTRQPDPAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGR 448 + + L++G+ LG ++ LT +P A VA+E+ L++ R ++ + P L L Sbjct 403 -LEVTRLQRGSSLGEMSLLTGEPRAATVVAVEDSLLLELDRPAFARMFASNPGLAHRLSA 461 Query 449 VIDERQ 454 ++ +R+ Sbjct 462 LLAQRR 467 >gi|158423266|ref|YP_001524558.1| mechanosensitive ion channel protein [Azorhizobium caulinodans ORS 571] gi|158330155|dbj|BAF87640.1| putative mechanosensitive ion channel protein [Azorhizobium caulinodans ORS 571] Length=507 Score = 109 bits (273), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 100/351 (29%), Positives = 159/351 (46%), Gaps = 17/351 (4%) Query 123 IGIGLAVILSYIWGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWL 182 +G L+V+ + ++ V VG L A GV ++V+GL LQ+++ + SG+ + +P+ + DW+ Sbjct 128 VGAALSVV-ADVFSVPVGTLIATSGVVAIVLGLALQSTLADLFSGIALNISRPYGVGDWV 186 Query 183 ETPTA-RGRVVEVNWRAVH-IDTGSGLQIMPNSMLATTAFTNLSRPAGAHECSITTTFST 240 P GRV+E NWRA H + +G+ L I+PNS LA TN S P H + Sbjct 187 ILPNGVEGRVIETNWRATHLLSSGNDLVILPNSNLAKEMLTNASGPERRHGVKLRVRLVP 246 Query 241 SDPPDKVCAMLNRAASA----LPHVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATF 296 + P + +L A S+ L H P V T+ A + + + + Sbjct 247 TLAPLALARVLRDALSSSTLILSHPAPAVHIKTLDAQAVDLELSFHVAELGASSAAKDEM 306 Query 297 LRWVWYAARREGLHL----DEADDEFSTAERVES--ALRTVVGPEL--RLSSSDQQSLAR 348 V+ A+ GLHL D +E + +LR + L LS ++ +LA Sbjct 307 FDLVYRHAKAAGLHLAAPAGAGGDSVPRSEVSQRPLSLRLLDSVALFSSLSEEEKAALAD 366 Query 349 YARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLGLTALT 408 Y DE+V G V + V +G + LT + D I L G +G + Sbjct 367 AMEQRAYRKDEVVAREGEVLSVLMIVRSGILGLTRSA-DAPGAEIHRLAPGDLIGEEGVL 425 Query 409 RQPDPAGAV-ALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQ 458 AG V AL V A I +E L ++ ++P L ELG ++ +R+ A Sbjct 426 LGEGEAGTVRALTYVVAFAIAKEALAPLLKDRPGLADELGALLAQRRETAH 476 >gi|330827988|ref|YP_004390940.1| small conductance mechanosensitive ion channel (MscS) family transporter [Aeromonas veronii B565] gi|328803124|gb|AEB48323.1| Transporter, small conductance mechanosensitive ion channel (MscS) family [Aeromonas veronii B565] Length=508 Score = 109 bits (272), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 102/416 (25%), Positives = 183/416 (44%), Gaps = 45/416 (10%) Query 76 VLTTAFGFLVLVLLLSLLNATLFQGAPQQSWRKRLPAIFVDVARFALIGIGLAVILSYIW 135 +L +G L+ LL L + R+P I D+ + IG + Y Sbjct 87 ILVKIWGILLFEFLLPLCHV-------------RIPRIIADIV-ITIGYIGWGLFRLYAS 132 Query 136 GVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDWLETPTARGRVVEVN 195 G+ +G + V + VI +Q+++G +++G+ + + I DWL+ T +GRVVE+N Sbjct 133 GMALGEIVTTSAVITAVIAFAMQDTLGNLLAGVSIQLDNSIAIGDWLQVDTTQGRVVEIN 192 Query 196 WRAVHIDTGSGLQ-IMPNSMLATTAFTNLSRPAGA---HECSITTTFSTSDPPDKVCAML 251 WRA I+T + ++PNS L FT L R G + + P ++ A++ Sbjct 193 WRATTIETRNWETVVIPNSHLLKQRFTVLGRRRGEPLQWRRWVWFDLTLDTLPTQIIALI 252 Query 252 NRA--ASALP----HVKPGVVPATIARGAAEYRTTVRLTSPADEGPTQATFLRWVWYAAR 305 ++ + LP H +P + + G A Y LT A + PT + + A R Sbjct 253 EKSLRETKLPCVAKHPQPDCLLMNVEGGIARYAVRYWLTDLARDDPTDSMVRSLIDAALR 312 Query 306 R----------------EGLHLDEADDEFSTAERVESALRTVVGPELRLSSSDQQSLARY 349 R E HLD A + TAER ++ + + L ++ LA Sbjct 313 RNDRRLTPPIFNVFMAKEKQHLD-ARHKRHTAERTDTLRKLPLFA--MLQENELLQLADQ 369 Query 350 ARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTFLG-LTALT 408 + + + +I+ G V + ++ G + V +G + + TL G F G L+ LT Sbjct 370 VKFAPFVSGDIMLEQGDVSSWLFVLVKGEAEMVVNV-EGRELKLGTLNAGDFFGELSLLT 428 Query 409 RQPDPAGAVALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDERQRKAQQAIRRD 464 +P A+ V +I + +++VM + L++ L RV+ +RQ++ + + R+ Sbjct 429 GEPSSFTVRAVATVETYRINQAMFQELVMQREALVEPLYRVLSDRQQEQRALLERE 484 >gi|222087270|ref|YP_002545805.1| mechanosensitive ion channel protein [Agrobacterium radiobacter K84] gi|221724718|gb|ACM27874.1| mechanosensitive ion channel protein [Agrobacterium radiobacter K84] Length=503 Score = 108 bits (269), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 91/353 (26%), Positives = 162/353 (46%), Gaps = 25/353 (7%) Query 125 IGLAVILSYI---WGVRVGGLFAALGVTSVVIGLMLQNSVGQIVSGLFMLFEQPFRIDDW 181 I L ILS + + V +G L A GV ++++GL LQ+++ + SGL + +P+ I DW Sbjct 116 IYLGAILSVVADVFSVPIGTLIATSGVFAIILGLALQSTLSDVFSGLALNLGRPYSIGDW 175 Query 182 LETPT-ARGRVVEVNWRAVHIDTGSG-LQIMPNSMLATTAFTNLSRPAGAHECSITTTFS 239 + +GRVVE NWRA H+ G+ L ++PNS LA T TNLS P +H +IT Sbjct 176 VVLDNDIQGRVVETNWRATHLLNGTNDLVVIPNSTLAKTRITNLSSPDESHGVTITVRVQ 235 Query 240 TSDPPDKVCAMLNRAASALPHVK----PGVVPATIARGAAEYRTTVRLTSPADEGPTQAT 295 + P+ + ++ + ++ P V+ +I A E + T R+ + + Sbjct 236 PTTQPNVIAEVMRNVLISCNTIQKTPEPSVMVNSIDAQAVELQLTFRIRDISQTTAAKNE 295 Query 296 FLRWVWYAARREGLHL------------DEADDEFSTAERVESALRTVVGPEL--RLSSS 341 ++ ++ GL L + A+ S A+ + R + L L+ Sbjct 296 IYDLIYRHSKAGGLKLAGPPGAIMMPSEERAEVAASIAQHPGTPWRLLSNIPLFSSLTED 355 Query 342 DQQSLARYARLVRYGTDEIVQHAGVVPMGITFVIAGSVRLTVTTDDGSVVAIATLKKGTF 401 +++ LA + + Y D ++ G +T V +G V +T + + + L G + Sbjct 356 EKEHLASHMQRHTYRKDTVIAEQGTRLRALTIVRSGVVSIT-RKEAQRQIELTRLAPGDY 414 Query 402 LGLTALTRQPDPAGAV-ALEEVTALQIGREHLEQVVMNKPMLLQELGRVIDER 453 G L G + AL V +I + L ++ ++P L +ELG ++ +R Sbjct 415 FGEAGLLMDTGEVGTIKALTFVVTYEISEDCLAPLLRDRPSLAEELGAILSKR 467 Lambda K H 0.322 0.136 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1020034159852 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40