BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2435c

Length=730
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609572|ref|NP_216951.1|  cyclase [Mycobacterium tuberculosis...  1492    0.0   
gi|289448079|ref|ZP_06437823.1|  cyclase [Mycobacterium tuberculo...  1490    0.0   
gi|339632462|ref|YP_004724104.1|  cyclase [Mycobacterium africanu...  1489    0.0   
gi|289746218|ref|ZP_06505596.1|  conserved hypothetical protein [...  1442    0.0   
gi|240170850|ref|ZP_04749509.1|  putative cyclase [Mycobacterium ...  1201    0.0   
gi|183983737|ref|YP_001852028.1|  adenylate or guanylate cyclase ...  1179    0.0   
gi|296170504|ref|ZP_06852091.1|  adenylate and guanylate cyclase ...  1004    0.0   
gi|118464838|ref|YP_880971.1|  adenylate and guanylate cyclase ca...   997    0.0   
gi|336458214|gb|EGO37195.1|  family 3 adenylate cyclase [Mycobact...   993    0.0   
gi|41408348|ref|NP_961184.1|  hypothetical protein MAP2250c [Myco...   993    0.0   
gi|254819843|ref|ZP_05224844.1|  adenylate and guanylate cyclase ...   976    0.0   
gi|240170840|ref|ZP_04749499.1|  adenylate or guanylate cyclase [...   974    0.0   
gi|342857830|ref|ZP_08714486.1|  adenylate and guanylate cyclase ...   974    0.0   
gi|254820709|ref|ZP_05225710.1|  hypothetical protein MintA_12321...   951    0.0   
gi|336457930|gb|EGO36921.1|  family 3 adenylate cyclase [Mycobact...   950    0.0   
gi|342860844|ref|ZP_08717494.1|  hypothetical protein MCOL_18273 ...   949    0.0   
gi|254775649|ref|ZP_05217165.1|  hypothetical protein MaviaA2_134...   948    0.0   
gi|41407377|ref|NP_960213.1|  hypothetical protein MAP1279c [Myco...   947    0.0   
gi|183983735|ref|YP_001852026.1|  adenylate or guanylate cyclase ...   921    0.0   
gi|118618964|ref|YP_907296.1|  adenylate or guanylate cyclase [My...   902    0.0   
gi|333990119|ref|YP_004522733.1|  adenylate or guanylate cyclase ...   894    0.0   
gi|118469724|ref|YP_887881.1|  cyclase [Mycobacterium smegmatis s...   876    0.0   
gi|229818726|ref|YP_002880252.1|  adenylate/guanylate cyclase wit...   583    3e-164
gi|326332469|ref|ZP_08198745.1|  putative adenylate cyclase [Noca...   487    3e-135
gi|332709914|ref|ZP_08429870.1|  adenylate cyclase, family 3 prot...   479    6e-133
gi|158334574|ref|YP_001515746.1|  cyclase [Acaryochloris marina M...   479    8e-133
gi|307151657|ref|YP_003887041.1|  integral membrane sensor-contai...   469    8e-130
gi|126657175|ref|ZP_01728341.1|  putative cyclase (adenylyl-or gu...   431    3e-118
gi|254425372|ref|ZP_05039090.1|  Adenylate and Guanylate cyclase ...   419    8e-115
gi|336036484|gb|AEH82415.1|  putative cyclase (adenylyl-or guanyl...   392    1e-106
gi|333814333|gb|AEG07001.1|  adenylate/guanylate cyclase with int...   392    2e-106
gi|300864236|ref|ZP_07109119.1|  putative Adenylate/guanylate cyc...   378    2e-102
gi|300866763|ref|ZP_07111445.1|  putative Globin domain protein [...   377    4e-102
gi|220906967|ref|YP_002482278.1|  adenylate/guanylate cyclase wit...   357    5e-96 
gi|254425852|ref|ZP_05039569.1|  Globin domain protein [Synechoco...   343    8e-92 
gi|158425589|ref|YP_001526881.1|  adenylate cyclase [Azorhizobium...   332    1e-88 
gi|262275612|ref|ZP_06053421.1|  methyl-accepting chemotaxis prot...   244    3e-62 
gi|83815947|ref|YP_446697.1|  methyl-accepting chemotaxis protein...   240    7e-61 
gi|294508633|ref|YP_003572692.1|  methyl-accepting chemotaxis pro...   240    8e-61 
gi|260777498|ref|ZP_05886392.1|  methyl-accepting chemotaxis prot...   221    3e-55 
gi|124003802|ref|ZP_01688650.1|  PAS domain S-box protein [Micros...   221    3e-55 
gi|331006729|ref|ZP_08330002.1|  methyl-accepting chemotaxis sens...   212    2e-52 
gi|323497131|ref|ZP_08102151.1|  methyl-accepting chemotaxis prot...   211    5e-52 
gi|170724924|ref|YP_001758950.1|  methyl-accepting chemotaxis sen...   209    1e-51 
gi|254506531|ref|ZP_05118672.1|  methyl-accepting chemotaxis prot...   207    8e-51 
gi|320158661|ref|YP_004191039.1|  methyl-accepting chemotaxis pro...   206    1e-50 
gi|335043473|ref|ZP_08536500.1|  methyl-accepting chemotaxis sens...   206    1e-50 
gi|343498784|ref|ZP_08736800.1|  methyl-accepting chemotaxis prot...   204    3e-50 
gi|330448376|ref|ZP_08312024.1|  HAMP domain protein [Photobacter...   204    4e-50 
gi|27366778|ref|NP_762305.1|  methyl-accepting chemotaxis protein...   204    4e-50 


>gi|15609572|ref|NP_216951.1| cyclase [Mycobacterium tuberculosis H37Rv]
 gi|15841955|ref|NP_336992.1| adenylate cyclase, putative [Mycobacterium tuberculosis CDC1551]
 gi|31793615|ref|NP_856108.1| putative cyclase (adenylyl-or guanylyl-)(adenylate-or guanylate-) 
[Mycobacterium bovis AF2122/97]
 56 more sequence titles
 Length=730

 Score = 1492 bits (3862),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 729/730 (99%), Positives = 730/730 (100%), Gaps = 0/730 (0%)

Query  1    LTSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY  60
            +TSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY
Sbjct  1    MTSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY  60

Query  61   QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL  120
            QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL
Sbjct  61   QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL  120

Query  121  ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ  180
            ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ
Sbjct  121  ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ  180

Query  181  DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI  240
            DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI
Sbjct  181  DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI  240

Query  241  LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA  300
            LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA
Sbjct  241  LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA  300

Query  301  LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG  360
            LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG
Sbjct  301  LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG  360

Query  361  TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD  420
            TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD
Sbjct  361  TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD  420

Query  421  LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK  480
            LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK
Sbjct  421  LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK  480

Query  481  ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE  540
            ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE
Sbjct  481  ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE  540

Query  541  RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER  600
            RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER
Sbjct  541  RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER  600

Query  601  IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS  660
            IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS
Sbjct  601  IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS  660

Query  661  GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE  720
            GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE
Sbjct  661  GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE  720

Query  721  EPIYRLSERS  730
            EPIYRLSERS
Sbjct  721  EPIYRLSERS  730


>gi|289448079|ref|ZP_06437823.1| cyclase [Mycobacterium tuberculosis CPHL_A]
 gi|289421037|gb|EFD18238.1| cyclase [Mycobacterium tuberculosis CPHL_A]
Length=730

 Score = 1490 bits (3857),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 728/730 (99%), Positives = 729/730 (99%), Gaps = 0/730 (0%)

Query  1    LTSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY  60
            +TSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY
Sbjct  1    MTSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY  60

Query  61   QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL  120
            QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL
Sbjct  61   QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL  120

Query  121  ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ  180
            ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ
Sbjct  121  ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ  180

Query  181  DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI  240
            DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI
Sbjct  181  DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI  240

Query  241  LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA  300
            LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA
Sbjct  241  LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA  300

Query  301  LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG  360
            LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG
Sbjct  301  LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG  360

Query  361  TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD  420
            TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD
Sbjct  361  TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD  420

Query  421  LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK  480
            LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK
Sbjct  421  LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK  480

Query  481  ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE  540
            ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE
Sbjct  481  ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE  540

Query  541  RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER  600
            RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER
Sbjct  541  RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER  600

Query  601  IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS  660
            IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS
Sbjct  601  IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS  660

Query  661  GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE  720
            GLVGRSSVVYDMWGAAVSL YQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE
Sbjct  661  GLVGRSSVVYDMWGAAVSLVYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE  720

Query  721  EPIYRLSERS  730
            EPIYRLSERS
Sbjct  721  EPIYRLSERS  730


>gi|339632462|ref|YP_004724104.1| cyclase [Mycobacterium africanum GM041182]
 gi|339331818|emb|CCC27521.1| putative cyclase (adenylyl-or guanylyl-)(adenylate-or guanylate-) 
[Mycobacterium africanum GM041182]
Length=730

 Score = 1489 bits (3856),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 728/730 (99%), Positives = 729/730 (99%), Gaps = 0/730 (0%)

Query  1    LTSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY  60
            +TSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY
Sbjct  1    MTSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY  60

Query  61   QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL  120
            QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL
Sbjct  61   QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL  120

Query  121  ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ  180
            ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ
Sbjct  121  ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ  180

Query  181  DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI  240
            DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI
Sbjct  181  DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI  240

Query  241  LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA  300
            LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA
Sbjct  241  LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA  300

Query  301  LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG  360
            LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG
Sbjct  301  LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG  360

Query  361  TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD  420
            TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD
Sbjct  361  TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD  420

Query  421  LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK  480
            LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK
Sbjct  421  LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK  480

Query  481  ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE  540
            ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE
Sbjct  481  ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE  540

Query  541  RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER  600
            RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER
Sbjct  541  RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER  600

Query  601  IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS  660
            IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS
Sbjct  601  IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS  660

Query  661  GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE  720
            GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQF AAGTISVGGLE
Sbjct  661  GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFKAAGTISVGGLE  720

Query  721  EPIYRLSERS  730
            EPIYRLSERS
Sbjct  721  EPIYRLSERS  730


>gi|289746218|ref|ZP_06505596.1| conserved hypothetical protein [Mycobacterium tuberculosis 02_1987]
 gi|308232130|ref|ZP_07415043.2| cyclase [Mycobacterium tuberculosis SUMu001]
 gi|308369716|ref|ZP_07418817.2| putative adenylate and Guanylate cyclase catalytic domain protein 
[Mycobacterium tuberculosis SUMu002]
 17 more sequence titles
 Length=706

 Score = 1442 bits (3733),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 705/706 (99%), Positives = 706/706 (100%), Gaps = 0/706 (0%)

Query  25   VLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKR  84
            +LRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKR
Sbjct  1    MLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKR  60

Query  85   AVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITP  144
            AVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITP
Sbjct  61   AVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITP  120

Query  145  VERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSY  204
            VERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSY
Sbjct  121  VERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSY  180

Query  205  FREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVD  264
            FREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVD
Sbjct  181  FREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVD  240

Query  265  FTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMG  324
            FTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMG
Sbjct  241  FTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMG  300

Query  325  SGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATE  384
            SGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATE
Sbjct  301  SGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATE  360

Query  385  GLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRA  444
            GLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRA
Sbjct  361  GLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRA  420

Query  445  LVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAA  504
            LVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAA
Sbjct  421  LVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAA  480

Query  505  FNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADIL  564
            FNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADIL
Sbjct  481  FNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADIL  540

Query  565  GVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPR  624
            GVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPR
Sbjct  541  GVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPR  600

Query  625  TVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMH  684
            TVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMH
Sbjct  601  TVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMH  660

Query  685  SGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSERS  730
            SGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSERS
Sbjct  661  SGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSERS  706


>gi|240170850|ref|ZP_04749509.1| putative cyclase [Mycobacterium kansasii ATCC 12478]
Length=689

 Score = 1201 bits (3106),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 587/689 (86%), Positives = 644/689 (94%), Gaps = 0/689 (0%)

Query  42   VLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYE  101
            +LLLL+SIVSVAA+  + YQ+GR SLR AAYERLT+LRESQKRA+ETLFSDLTNSLVIY 
Sbjct  1    MLLLLSSIVSVAAVVIVGYQTGRASLREAAYERLTELRESQKRAIETLFSDLTNSLVIYA  60

Query  102  RGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPT  161
            RGLTVV AV +FTAGFDQLADATI+PAQQQAIVNYYNN+ I PVERTTG+KLDITALLPT
Sbjct  61   RGLTVVQAVAQFTAGFDQLADATINPAQQQAIVNYYNNQLIKPVERTTGEKLDITALLPT  120

Query  162  SPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLD  221
            SPAQ+YLQAYYTAPFTSDQD+MR DDAGDGSAWSAANA+FN YFREIVTRFDYDDAVLLD
Sbjct  121  SPAQKYLQAYYTAPFTSDQDSMRFDDAGDGSAWSAANARFNGYFREIVTRFDYDDAVLLD  180

Query  222  TRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVP  281
            TRGNIVY+LSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQL VP
Sbjct  181  TRGNIVYSLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLDVP  240

Query  282  TAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSD  341
            TAWLVAPV+A G+TQGV+ALPLPI KIN+IMTA++QWQ+AGMG GTETYLAGPDSLMRSD
Sbjct  241  TAWLVAPVQADGRTQGVIALPLPIAKINRIMTANQQWQSAGMGRGTETYLAGPDSLMRSD  300

Query  342  SRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTD  401
            SRLF++DP+EYR+Q VAAGT LDVVNRAIQ GGTTLLQPVA+ GLRAAQRGQTGT+T+TD
Sbjct  301  SRLFVEDPDEYRRQSVAAGTPLDVVNRAIQLGGTTLLQPVASAGLRAAQRGQTGTITATD  360

Query  402  YTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASM  461
            YT ++ELEAYAPL+VP+SDLHWSILATR++SEAFAAVA+FSRALVLVTV II+ ICVASM
Sbjct  361  YTDNKELEAYAPLDVPNSDLHWSILATRDNSEAFAAVAAFSRALVLVTVAIILGICVASM  420

Query  462  LIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNE  521
            LIA AMVRP+RRLE GTQKISAGDY+V IPV +RDEIGDLTAAFNEMSRNL+ KE LLNE
Sbjct  421  LIAQAMVRPVRRLEAGTQKISAGDYDVTIPVTTRDEIGDLTAAFNEMSRNLEIKEGLLNE  480

Query  522  QRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKI  581
            QR+ENDRLLLSMMPEPVV+RYR GE+TIAQEHQDV V+FADILG+D+IS  LSGNELV I
Sbjct  481  QRRENDRLLLSMMPEPVVQRYREGEKTIAQEHQDVAVIFADILGLDDISRDLSGNELVGI  540

Query  582  VDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNC  641
            VD+L RQFDSAAE LGVERIRTLHNGYLA CGVTTPRLDN+ RT+DFALEMRRI+DRFN 
Sbjct  541  VDDLFRQFDSAAESLGVERIRTLHNGYLASCGVTTPRLDNVARTIDFALEMRRIIDRFNR  600

Query  642  QTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEA  701
            QTG++L LR GINTG+VISGLVGRSSVVYDMWGAAVSLAYQ HSGSPQPGIYVTS VYEA
Sbjct  601  QTGHELRLRAGINTGNVISGLVGRSSVVYDMWGAAVSLAYQTHSGSPQPGIYVTSPVYEA  660

Query  702  MRDVWQFTAAGTISVGGLEEPIYRLSERS  730
            MRDV QFT AGTISVGG+++PIYRLSERS
Sbjct  661  MRDVRQFTPAGTISVGGVDQPIYRLSERS  689


>gi|183983737|ref|YP_001852028.1| adenylate or guanylate cyclase [Mycobacterium marinum M]
 gi|183177063|gb|ACC42173.1| adenylate or guanylate cyclase [Mycobacterium marinum M]
Length=719

 Score = 1179 bits (3049),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 583/717 (82%), Positives = 645/717 (90%), Gaps = 0/717 (0%)

Query  14   ESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYE  73
            E  PA    K   RRRPRFR SIQSKLMVLLLL+SIVSVAAI A+ + +GR+SL AAAY 
Sbjct  3    EGAPAHDGAKGTRRRRPRFRVSIQSKLMVLLLLSSIVSVAAIVAVGFHTGRSSLSAAAYG  62

Query  74   RLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAI  133
            RLTQLRESQ RAVETLFSDLTNSLVIY RGLTV+DAV +FTAGFDQLADATISPAQQ+++
Sbjct  63   RLTQLRESQLRAVETLFSDLTNSLVIYARGLTVIDAVAQFTAGFDQLADATISPAQQESL  122

Query  134  VNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSA  193
            VNYYN++ I PVE  TG KLD+ ALLPTSPAQ+YLQAYYTAPFTSDQD+MRLDDAGDGSA
Sbjct  123  VNYYNDQLIKPVEHLTGTKLDLEALLPTSPAQKYLQAYYTAPFTSDQDSMRLDDAGDGSA  182

Query  194  WSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDA  253
            WSAANA+FN YFREIVTRFDYDDAVLLDTRGNIVY+LSKDPDLGTNILTGPYRESNLRDA
Sbjct  183  WSAANAEFNGYFREIVTRFDYDDAVLLDTRGNIVYSLSKDPDLGTNILTGPYRESNLRDA  242

Query  254  YLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMT  313
            YL+ALGANAVDFTWITDF+PYQPQL   TAWLV+PV  GG+T+GVLALPLPI KINK+MT
Sbjct  243  YLRALGANAVDFTWITDFEPYQPQLDAATAWLVSPVLQGGRTEGVLALPLPIAKINKMMT  302

Query  314  ADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFG  373
            AD+ WQAAGMG+GTETYLAGPD+LMRSDSRLFLQDPEEYR+Q VAAGTS +VVNRAIQ G
Sbjct  303  ADKNWQAAGMGTGTETYLAGPDNLMRSDSRLFLQDPEEYRRQAVAAGTSPEVVNRAIQLG  362

Query  374  GTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSE  433
             T LLQPVAT GLR AQRGQTGTV++ DYTG+RELEA+APLN+P+SDLHWSILAT +DS 
Sbjct  363  STVLLQPVATAGLREAQRGQTGTVSAVDYTGNRELEAFAPLNIPNSDLHWSILATNDDSA  422

Query  434  AFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVK  493
            AFAA A+FS+ALVLVTV +IV+ICV SMLIA  MVRPIRRLE GT+KIS GDY+V IPVK
Sbjct  423  AFAAAAAFSKALVLVTVAMIVIICVFSMLIAQLMVRPIRRLEAGTEKISGGDYDVAIPVK  482

Query  494  SRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEH  553
            SRDEIGDLTAAFNEMSR+L  KE+LLNEQR+ENDRLLLSMMPEPVV+RYR GEQTIAQEH
Sbjct  483  SRDEIGDLTAAFNEMSRSLNIKEDLLNEQRRENDRLLLSMMPEPVVQRYREGEQTIAQEH  542

Query  554  QDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCG  613
            QDVTV+FADILG+DE+S  LSGNEL+ IVD+L RQFDSAAE LGVERIRTLHNGYLA CG
Sbjct  543  QDVTVIFADILGLDEVSRSLSGNELIAIVDDLFRQFDSAAESLGVERIRTLHNGYLASCG  602

Query  614  VTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMW  673
            VTTPRLDN+ RTV FALEM+RI++RFN Q+G+ L LR GINTG+VISGLVGR+SVVYDMW
Sbjct  603  VTTPRLDNVARTVAFALEMQRIIERFNHQSGHQLRLRAGINTGNVISGLVGRTSVVYDMW  662

Query  674  GAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSERS  730
            GAAVS AYQMHSGSPQPGIYVTSQVYEAMRD  QF  AGTI+VGG E+ IYR+SE+S
Sbjct  663  GAAVSTAYQMHSGSPQPGIYVTSQVYEAMRDERQFAPAGTIAVGGAEQQIYRMSEQS  719


>gi|296170504|ref|ZP_06852091.1| adenylate and guanylate cyclase catalytic domain protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295894856|gb|EFG74578.1| adenylate and guanylate cyclase catalytic domain protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=744

 Score = 1004 bits (2595),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 492/730 (68%), Positives = 601/730 (83%), Gaps = 1/730 (0%)

Query  2    TSGEALDSVAESESTP-AKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY  60
            T+ E      E+ + P  + R     RRR  FR  +QSKL++ LLL SI+S+  I  I  
Sbjct  15   TAPERAQPTTETTAAPEGEARAIQKPRRRRVFRIGLQSKLLLTLLLCSILSIGVIGFIGA  74

Query  61   QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL  120
             SGRT+LR    ERLT+LRESQ R V+ LF ++TNSL++Y  G ++V+A   FT GF QL
Sbjct  75   SSGRTALRQVESERLTELRESQARQVQALFKEVTNSLIVYSGGFSIVEATTAFTDGFAQL  134

Query  121  ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ  180
            ++ATI+PAQQQA+VNYY+N  I P++R TG++LD  A+ P+S AQ+YLQAYYTAP +S  
Sbjct  135  SNATITPAQQQALVNYYDNNMIKPIKRITGEELDRNAIFPSSNAQKYLQAYYTAPNSSTA  194

Query  181  DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI  240
            +A ++DDAGDGSAWSAA+A++  Y R+IVTRF+Y DA+LLD +GN++++++K PDLGTNI
Sbjct  195  EARKVDDAGDGSAWSAASARYGFYLRDIVTRFEYPDALLLDMQGNVIFSVNKGPDLGTNI  254

Query  241  LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA  300
            LTGPYRESNLRDAY KAL +N ++F WITDF+PYQPQL VPTAW+V+PV   GK  GV+A
Sbjct  255  LTGPYRESNLRDAYQKALRSNDLNFVWITDFQPYQPQLDVPTAWVVSPVGMNGKFNGVMA  314

Query  301  LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG  360
            LPLPI KINKIMTAD+ W+AAGMG  TETYLAGPD+LMRSDSRLFL+DP EYR++ VAAG
Sbjct  315  LPLPISKINKIMTADKHWEAAGMGPATETYLAGPDNLMRSDSRLFLEDPAEYRREAVAAG  374

Query  361  TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD  420
            T  +VV  AI+ GGTTL+QPVAT GLRAA RGQTG +++TDY G+RELEAYAPL VP+SD
Sbjct  375  TPPEVVEEAIRLGGTTLVQPVATAGLRAAHRGQTGVLSATDYLGNRELEAYAPLTVPNSD  434

Query  421  LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK  480
            L+WSILATR++S+AFA +  FSR LVL    +I  ICVASM++A  M+RPIRRL+ GTQK
Sbjct  435  LNWSILATRDNSDAFARLGRFSRTLVLAVAIMIFAICVASMVLAQLMLRPIRRLQAGTQK  494

Query  481  ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE  540
            IS+GDYEVNIPVK+RDEIG+LTAAFNEMSRNL  KEELLNEQR+ENDRLLL++MPE VV+
Sbjct  495  ISSGDYEVNIPVKTRDEIGELTAAFNEMSRNLAIKEELLNEQRRENDRLLLALMPESVVQ  554

Query  541  RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER  600
            RYR G++TIAQEHQDV ++FA+I+G+DE+S+ LSG+ELV IVDEL RQFDSAAE LGVER
Sbjct  555  RYREGQETIAQEHQDVAIIFAEIVGLDEVSADLSGDELVGIVDELFRQFDSAAESLGVER  614

Query  601  IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS  660
            IRT HNGYLA CGV TPRLD+I R+VDFA+EMR I++RFN  TG++L LRVGI+TG+VIS
Sbjct  615  IRTFHNGYLASCGVVTPRLDSIHRSVDFAMEMRHIIERFNSSTGHELRLRVGISTGNVIS  674

Query  661  GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE  720
            GLVGRS +VYDMWGAAVSLAYQM SGS Q GIYVTSQVY+AMRDV QF  AGTISVGG +
Sbjct  675  GLVGRSGLVYDMWGAAVSLAYQMQSGSSQSGIYVTSQVYDAMRDVRQFAPAGTISVGGTD  734

Query  721  EPIYRLSERS  730
            + IYRLSERS
Sbjct  735  QAIYRLSERS  744


>gi|118464838|ref|YP_880971.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium avium 104]
 gi|254774561|ref|ZP_05216077.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium avium subsp. avium ATCC 25291]
 gi|118166125|gb|ABK67022.1| adenylate and Guanylate cyclase catalytic domain protein [Mycobacterium 
avium 104]
Length=731

 Score =  997 bits (2577),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 469/701 (67%), Positives = 575/701 (83%), Gaps = 0/701 (0%)

Query  29   RPRFRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVET  88
            R RFR  IQSK+++ +LL+SI+ VA I  I   SGR +LR    ERL +LRE QKRAV+ 
Sbjct  31   RSRFRFGIQSKILITMLLSSILGVAVIGLIGAVSGRNALRQVESERLIELREGQKRAVQA  90

Query  89   LFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT  148
            LF ++TNSL+++  G T+ +A    T GF QLA+ATI+PAQQQ +VNYY+N+ + P++  
Sbjct  91   LFREVTNSLIVWSGGFTINEATAALTTGFAQLANATITPAQQQQLVNYYDNQMLKPIKHA  150

Query  149  TGDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREI  208
            TGD +DI A+LP S AQ+Y+QAYYTA      D++ + DAGDGSAWSAANA+F+ Y R+I
Sbjct  151  TGDSIDINAVLPNSNAQKYVQAYYTAAPRPTPDSLPVQDAGDGSAWSAANARFDFYVRDI  210

Query  209  VTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWI  268
             TRFDY DA+LLDT+GN+VY++ K PDLGTNILTGPYRES LR+AY KAL +N VDF WI
Sbjct  211  ATRFDYRDALLLDTQGNVVYSVMKGPDLGTNILTGPYRESKLREAYQKALASNDVDFVWI  270

Query  269  TDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTE  328
            TDF+PYQPQL  PTAW+V+PV   G+ +GV+ALP+P  KINKIMTA   W+AAGMG  TE
Sbjct  271  TDFQPYQPQLDAPTAWVVSPVGMNGRIEGVMALPVPAAKINKIMTAGGHWEAAGMGPATE  330

Query  329  TYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRA  388
            TYLAGPD LMRSDSR+F++DP++YR+  + AGT  DVV+RAI  GGTTL+QPVAT GLRA
Sbjct  331  TYLAGPDDLMRSDSRVFVEDPQQYRRDAIDAGTPPDVVDRAIHLGGTTLVQPVATAGLRA  390

Query  389  AQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLV  448
            AQRG+TG VT+TDY G+RELEAYAPLN+P+SDLHWSILATR++S+AFA +  FS+ LV+ 
Sbjct  391  AQRGETGVVTATDYMGNRELEAYAPLNIPNSDLHWSILATRDNSDAFARLGRFSKNLVIA  450

Query  449  TVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEM  508
               +I VICVASM +A A VRP+RRLE GT+KIS+GDY++NIPV++RDEIGDLTAAFNEM
Sbjct  451  VTAMIFVICVASMFVAQAAVRPVRRLEEGTRKISSGDYDINIPVRARDEIGDLTAAFNEM  510

Query  509  SRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDE  568
            SRNL  KEELLNEQR+ENDRLLL++MPE V++RYR GE+TIAQ+HQDV +++ADI+G+DE
Sbjct  511  SRNLAIKEELLNEQRRENDRLLLALMPESVLQRYREGEETIAQKHQDVAIIYADIVGLDE  570

Query  569  ISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDF  628
            + + +   +LV  VDEL RQFDSAAE LGVERIRT HNGYLA CGV TPRLD+I R VDF
Sbjct  571  LFTEMPEAQLVGTVDELFRQFDSAAETLGVERIRTFHNGYLASCGVVTPRLDSIHRAVDF  630

Query  629  ALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSP  688
            ALE+ RI+DRFN QTG+ L LR+G+NTG+V+SGLVGRS +VYDMWG AVSLAYQMHSGSP
Sbjct  631  ALEIGRIIDRFNSQTGHQLGLRIGVNTGNVVSGLVGRSGLVYDMWGGAVSLAYQMHSGSP  690

Query  689  QPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSER  729
            QPGIYV+SQVYEAMRDV QF  AGTISVGG ++ IYRL ER
Sbjct  691  QPGIYVSSQVYEAMRDVRQFAPAGTISVGGTDQAIYRLLER  731


>gi|336458214|gb|EGO37195.1| family 3 adenylate cyclase [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=731

 Score =  993 bits (2567),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 468/701 (67%), Positives = 574/701 (82%), Gaps = 0/701 (0%)

Query  29   RPRFRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVET  88
            R RFR  IQSK+++ +LL+SI+ VA I  I   SGR +LR    ERL +LRE QKRAV+ 
Sbjct  31   RSRFRFGIQSKILITMLLSSILGVAVIGLIGAVSGRNALRQVESERLIELREGQKRAVQA  90

Query  89   LFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT  148
            LF ++TNSL+++  G T+ +A    TAGF +LA+ATI+PAQQQ +VNYY+N+ + P++  
Sbjct  91   LFREVTNSLIVWSGGFTINEATAALTAGFARLANATITPAQQQQLVNYYDNQMLKPIKHA  150

Query  149  TGDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREI  208
            TGD +DI A+LP S AQ+Y+QAYYTA      D++ + DAGDGSAWSAANA+F+ Y R+I
Sbjct  151  TGDSIDINAVLPNSNAQKYVQAYYTAAPRPTPDSLPVQDAGDGSAWSAANARFDFYVRDI  210

Query  209  VTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWI  268
             TRFDY DA+LLDT+GN+VY++ K PDLGTNILTGPYRES LR+AY KAL +N VDF WI
Sbjct  211  ATRFDYRDALLLDTQGNVVYSVMKGPDLGTNILTGPYRESKLREAYQKALASNDVDFVWI  270

Query  269  TDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTE  328
            TDF+PYQPQL  PTAW+V+PV   G+ +GV+ALP+P  KINKIMTA   W+AAGMG  TE
Sbjct  271  TDFQPYQPQLDAPTAWVVSPVGMNGRVEGVMALPVPAAKINKIMTAGGHWEAAGMGPATE  330

Query  329  TYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRA  388
            TYLAGPD LMRSDSR+F++DP++YR+  + AGT  DVV+RAI  GGTTL+QPVAT GLRA
Sbjct  331  TYLAGPDDLMRSDSRVFVEDPQQYRRDAIDAGTPPDVVDRAIHLGGTTLVQPVATAGLRA  390

Query  389  AQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLV  448
            AQRG+TG VT+TDY G+RELEAYAPLN+P+SDLHWSILATR++S+AFA +  FS+ LV+ 
Sbjct  391  AQRGETGVVTATDYMGNRELEAYAPLNIPNSDLHWSILATRDNSDAFARLGRFSKNLVIA  450

Query  449  TVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEM  508
               +I VICVASM +A A VRP+RRLE GT+KIS+GDY++NIPV++RDEIGDLTAAFNEM
Sbjct  451  VTAMIFVICVASMFVAQAAVRPVRRLEEGTRKISSGDYDINIPVRARDEIGDLTAAFNEM  510

Query  509  SRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDE  568
            SRNL  KEELLNEQR+ENDRLLL++MPE V++RYR GE+ IAQ+HQDV +++ADI+G+DE
Sbjct  511  SRNLAIKEELLNEQRRENDRLLLALMPESVLQRYREGEEAIAQKHQDVAIIYADIVGLDE  570

Query  569  ISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDF  628
            + + +   +LV  VDEL RQFDSAAE LGVERIRT HNGYLA CGV TPRLD+I R VDF
Sbjct  571  LFTEMPEAQLVGTVDELFRQFDSAAETLGVERIRTFHNGYLASCGVVTPRLDSIHRAVDF  630

Query  629  ALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSP  688
            ALE+ RI+DRFN QTG+ L LRVG+NTG+V+SGLVGRS +VYDMWG AVSLAYQMHSGSP
Sbjct  631  ALEIGRIIDRFNSQTGHQLGLRVGVNTGNVVSGLVGRSGLVYDMWGGAVSLAYQMHSGSP  690

Query  689  QPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSER  729
            QPG YV+SQVYEAMRDV QF  AGTISVGG ++ IYRL ER
Sbjct  691  QPGNYVSSQVYEAMRDVRQFAPAGTISVGGTDQAIYRLLER  731


>gi|41408348|ref|NP_961184.1| hypothetical protein MAP2250c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41396704|gb|AAS04567.1| hypothetical protein MAP_2250c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=731

 Score =  993 bits (2566),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 468/701 (67%), Positives = 574/701 (82%), Gaps = 0/701 (0%)

Query  29   RPRFRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVET  88
            R RFR  IQSK+++ +LL+SI+ VA I  I   SGR +LR    ERL +LRE QKRAV+ 
Sbjct  31   RSRFRFGIQSKILITMLLSSILGVAVIGLIGAVSGRNALRQVESERLIELREGQKRAVQA  90

Query  89   LFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT  148
            LF ++TNSL+++  G T+ +A    TAGF +LA+ATI+PAQQQ +VNYY+N+ + P++  
Sbjct  91   LFREVTNSLIVWSGGFTINEATAALTAGFARLANATITPAQQQQLVNYYDNQMLKPIKHA  150

Query  149  TGDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREI  208
            TGD +DI A+LP S AQ+Y+QAYYTA      D++ + DAGDGSAWSAAN +F+ Y R+I
Sbjct  151  TGDSIDINAVLPNSNAQKYVQAYYTAAPRPTPDSLPVQDAGDGSAWSAANVRFDFYVRDI  210

Query  209  VTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWI  268
             TRFDY DA+LLDT+GN+VY++ K PDLGTNILTGPYRES LR+AY KAL +N VDF WI
Sbjct  211  ATRFDYRDALLLDTQGNVVYSVMKGPDLGTNILTGPYRESKLREAYQKALASNDVDFVWI  270

Query  269  TDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTE  328
            TDF+PYQPQL  PTAW+V+PV   G+ +GV+ALP+P  KINKIMTA   W+AAGMG  TE
Sbjct  271  TDFQPYQPQLDAPTAWVVSPVGMNGRIEGVMALPVPAAKINKIMTAGGHWEAAGMGPATE  330

Query  329  TYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRA  388
            TYLAGPD LMRSDSR+F++DP++YR+  + AGT  DVV+RAI  GGTTL+QPVAT GLRA
Sbjct  331  TYLAGPDDLMRSDSRVFVEDPQQYRRDAIDAGTPPDVVDRAIHLGGTTLVQPVATAGLRA  390

Query  389  AQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLV  448
            AQRG+TG VT+TDY G+RELEAYAPLN+P+SDLHWSILATR++S+AFA +  FS+ LV+ 
Sbjct  391  AQRGETGVVTATDYMGNRELEAYAPLNIPNSDLHWSILATRDNSDAFARLGRFSKNLVIA  450

Query  449  TVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEM  508
               +I VICVASM +A A VRP+RRLE GT+KIS+GDY++NIPV++RDEIGDLTAAFNEM
Sbjct  451  VTAMIFVICVASMFVAQAAVRPVRRLEEGTRKISSGDYDINIPVRARDEIGDLTAAFNEM  510

Query  509  SRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDE  568
            SRNL  KEELLNEQR+ENDRLLL++MPE V++RYR GE+TIAQ+HQDV +++ADI+G+DE
Sbjct  511  SRNLAIKEELLNEQRRENDRLLLALMPESVLQRYREGEETIAQKHQDVAIIYADIVGLDE  570

Query  569  ISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDF  628
            + + +   +LV  VDEL RQFDSAAE LGVERIRT HNGYLA CGV TPRLD+I R VDF
Sbjct  571  LFTEMPEAQLVGTVDELFRQFDSAAETLGVERIRTFHNGYLASCGVVTPRLDSIHRAVDF  630

Query  629  ALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSP  688
            ALE+ RI+DRFN QTG+ L LRVG+NTG+V+SGLVGRS +VYDMWG AVSLAYQMHSGSP
Sbjct  631  ALEIGRIIDRFNSQTGHQLGLRVGVNTGNVVSGLVGRSGLVYDMWGGAVSLAYQMHSGSP  690

Query  689  QPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSER  729
            QPG YV+SQVYEAMRDV QF  AGTISVGG ++ IYRL ER
Sbjct  691  QPGNYVSSQVYEAMRDVRQFAPAGTISVGGTDQAIYRLLER  731


>gi|254819843|ref|ZP_05224844.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium intracellulare ATCC 13950]
Length=729

 Score =  976 bits (2523),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 461/729 (64%), Positives = 583/729 (80%), Gaps = 0/729 (0%)

Query  1    LTSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY  60
            +T+ E  D+    E  PA +      + R RFR  IQSK+++ +LL+SI+ VA I  I  
Sbjct  1    MTTSELTDAAPRIEPGPAHQPVTRTRQPRSRFRFGIQSKILITMLLSSILGVAVIGLIGA  60

Query  61   QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL  120
             SGRT+LR    ERL ++RESQKRAV+ LF +LT+SL++   G  + +A    +  F QL
Sbjct  61   VSGRTALREVESERLIEMRESQKRAVQALFRELTSSLIVQSGGFGINEATANLSTAFAQL  120

Query  121  ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ  180
            A+A I+PA++Q +VNYY N+ I P++R TG+ +D+ A+LP+S AQ+YLQA+YTA      
Sbjct  121  ANANITPAEEQTLVNYYENDMIKPIKRITGNAIDLKAVLPSSNAQKYLQAHYTAAPRPTA  180

Query  181  DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI  240
            D+   +DAGDGSAWSAANA+F+ + R IVTRFDY DA+LLD +GN+VY++ K PDLGTNI
Sbjct  181  DSPPAEDAGDGSAWSAANARFDFFLRGIVTRFDYRDALLLDMQGNVVYSVMKGPDLGTNI  240

Query  241  LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA  300
            LTGPYR SNLR AY KA+ +N VDF WITDF+ YQPQL  PTAW+V+PV   GK +GV+A
Sbjct  241  LTGPYRGSNLRGAYQKAVASNDVDFVWITDFQQYQPQLDTPTAWVVSPVGMNGKFEGVMA  300

Query  301  LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG  360
            LP+PI KIN IMTA++ W+ AGMG  TETYLAGPD LMRSDSR+F++DP++YR + + AG
Sbjct  301  LPVPIGKINTIMTANKHWEDAGMGPATETYLAGPDDLMRSDSRVFIEDPKQYRHEAIEAG  360

Query  361  TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD  420
            T  DVV+RA++ GGTTL+QPV T GLRAAQRG+TG +++TDYTG+RELEAYAPL++P+SD
Sbjct  361  TPPDVVDRALRLGGTTLVQPVPTAGLRAAQRGETGVMSATDYTGNRELEAYAPLDIPNSD  420

Query  421  LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK  480
            LHWSILATR++S+AFA +  FS+ LV+    +I  ICVASM +A A VRP+RRLE GT+K
Sbjct  421  LHWSILATRDNSDAFARLGRFSKNLVIAVTAMIFAICVASMFVAQAAVRPVRRLEEGTRK  480

Query  481  ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE  540
            IS+GDY++NIPV++RDEIGDLTAAFNEMSRNL  KEELLNEQR+ENDRL+L++MPE V++
Sbjct  481  ISSGDYDINIPVRTRDEIGDLTAAFNEMSRNLAIKEELLNEQRRENDRLMLALMPESVLQ  540

Query  541  RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER  600
            RYR GE+TIAQ+HQDV +++ADI+G+DE+ + +  +ELV  VDEL RQFDSAAE LGVER
Sbjct  541  RYREGEETIAQKHQDVAIIYADIVGLDEMFTEMPEDELVGTVDELFRQFDSAAESLGVER  600

Query  601  IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS  660
            IRT HNGYLA CGV TPRLD+I R VDFALE+ RI+DRFN Q+ + L LRVG+NTG+V+S
Sbjct  601  IRTFHNGYLASCGVVTPRLDSIHRAVDFALEIGRIIDRFNSQSRHQLGLRVGVNTGNVVS  660

Query  661  GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE  720
            GLVGRS +VYDMWG AVSLAYQMHSG+PQ GIYV+SQVYEAMRDV QFTAAGTISVGG +
Sbjct  661  GLVGRSGLVYDMWGGAVSLAYQMHSGAPQAGIYVSSQVYEAMRDVRQFTAAGTISVGGTD  720

Query  721  EPIYRLSER  729
            + IYRL ER
Sbjct  721  QAIYRLLER  729


>gi|240170840|ref|ZP_04749499.1| adenylate or guanylate cyclase [Mycobacterium kansasii ATCC 12478]
Length=697

 Score =  974 bits (2519),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 458/694 (66%), Positives = 563/694 (82%), Gaps = 0/694 (0%)

Query  36   IQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTN  95
            IQSKL+V LLL SI+SVA +    Y +GR +L+  A ERL +LRES KR +E LF + TN
Sbjct  3    IQSKLLVTLLLCSIMSVAVVGLTGYVTGRNALQQVATERLLELRESHKRQLEGLFGEFTN  62

Query  96   SLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDKLDI  155
            SL +Y  G + V A+  FT GF+QL++ATISPAQQ++IVNYY+N  + P+ + TGD +DI
Sbjct  63   SLEVYSSGFSAVQAIEAFTDGFNQLSNATISPAQQESIVNYYSNAVVKPISQLTGDDVDI  122

Query  156  TALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYD  215
             ALLPTS +Q+YLQA YT    S  +++   DAGDGS WSAANA++N +FR IVTRFDY 
Sbjct  123  NALLPTSNSQKYLQANYTPQCASATESVSCSDAGDGSTWSAANARYNDFFRGIVTRFDYR  182

Query  216  DAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQ  275
            DA+LLD  GN+VYT+SK PDLGTNI TGPYRE+ LRDAY KAL +N V+F WITDF+ YQ
Sbjct  183  DALLLDLHGNVVYTVSKGPDLGTNIFTGPYRETVLRDAYRKALRSNNVNFVWITDFQQYQ  242

Query  276  PQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPD  335
            PQL  PTAW+V+P+   GK +GV+ALPLPI KIN IM A + W+A GMG  TETYL GPD
Sbjct  243  PQLDAPTAWVVSPIGMAGKIEGVMALPLPISKINDIMNAHKHWEAVGMGRSTETYLVGPD  302

Query  336  SLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTG  395
            +LMRSDSRLFLQD ++Y+++ +A GT  DVV+ AI+ G T L+QPV + G+R A+RGQTG
Sbjct  303  NLMRSDSRLFLQDRDKYQREAIAGGTPRDVVDSAIRLGTTVLVQPVPSAGVRYAERGQTG  362

Query  396  TVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTVGIIVV  455
                TDY G+REL+AYAP++VP+SDLHWSILATR+D +A+  +++F + LVL   GI + 
Sbjct  363  VTKDTDYLGNRELQAYAPVDVPNSDLHWSILATRDDWDAYQRLSTFGKTLVLAVAGITLA  422

Query  456  ICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTK  515
            ICV SML+A  +VRPIRRLE GT++ISAGDYEV +PV+SRDE+GDLTAAFNEMSRNL+ K
Sbjct  423  ICVVSMLLAKLLVRPIRRLEAGTERISAGDYEVTVPVRSRDELGDLTAAFNEMSRNLKIK  482

Query  516  EELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSG  575
            EELLNEQRKENDRLLLS+MP PVV+RYR G QT+AQEHQDV V+FAD++G+D++S  LSG
Sbjct  483  EELLNEQRKENDRLLLSLMPAPVVQRYREGVQTVAQEHQDVAVIFADMVGLDDMSDDLSG  542

Query  576  NELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRI  635
            +ELV +V+EL RQFDSAAE LGVERIRT HNGYLA CG TTPRLDNI R+VDFA+E++RI
Sbjct  543  DELVAVVNELFRQFDSAAEALGVERIRTFHNGYLASCGATTPRLDNIHRSVDFAIEIQRI  602

Query  636  VDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVT  695
            +DRFN ++ + L LRVG+NTG VISGLVGR+S+ YDMWGAAVSLAYQMHSGSPQPGIYVT
Sbjct  603  IDRFNSRSRHKLRLRVGVNTGKVISGLVGRASLAYDMWGAAVSLAYQMHSGSPQPGIYVT  662

Query  696  SQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSER  729
            SQVYEAMRD+W+F  AGTISVGG E+ I+RL ER
Sbjct  663  SQVYEAMRDIWKFVPAGTISVGGSEQQIWRLVER  696


>gi|342857830|ref|ZP_08714486.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium colombiense CECT 3035]
 gi|342135163|gb|EGT88329.1| adenylate and guanylate cyclase catalytic domain-containing protein 
[Mycobacterium colombiense CECT 3035]
Length=730

 Score =  974 bits (2517),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 464/730 (64%), Positives = 582/730 (80%), Gaps = 1/730 (0%)

Query  1    LTSGEALDSVAESESTPAKKRHKNVLRRR-PRFRASIQSKLMVLLLLTSIVSVAAIAAIV  59
            +T+ E  D+    +  PA+   K   +R   RFR  IQSK+++ +LL+SI+ VA I AI 
Sbjct  1    MTTSELTDAEPHIDPEPAQPAAKRPRQRALARFRFGIQSKILITMLLSSILGVAVIGAIG  60

Query  60   YQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQ  119
              SGR +LR    ERL ++RESQKRAV+ LF +++NSL+ +  G  +  A    TA F Q
Sbjct  61   AASGRNALRQVESERLIEMRESQKRAVQALFREVSNSLITWSGGFGINQATTALTADFAQ  120

Query  120  LADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSD  179
            L +A ISPAQQQ++V+YY+N+ I P++R TGD +DI A+LP+S AQ+Y+QAYYTA     
Sbjct  121  LNNAQISPAQQQSLVDYYDNDMIKPIKRITGDTIDIRAVLPSSNAQKYIQAYYTAAPRPG  180

Query  180  QDAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTN  239
             DA+   DAGDGSAWSAANA+F+ Y R IVTRFDY DA+LLD +GN+VY++ K PDLGTN
Sbjct  181  PDALPAQDAGDGSAWSAANARFDFYMRGIVTRFDYRDALLLDMQGNVVYSVLKGPDLGTN  240

Query  240  ILTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVL  299
            ILTGPYRES LR+AY KAL +N +DF WITDF+ YQP L  PTAW+V+P+   GK +GV+
Sbjct  241  ILTGPYRESKLREAYQKALASNDLDFVWITDFQQYQPALDTPTAWVVSPIGMNGKFEGVM  300

Query  300  ALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAA  359
            ALP+P+ KINKIMTAD+ W+AAGMG  TETYLAGPD LMRSDSR F++DP+ YR+  + A
Sbjct  301  ALPVPVAKINKIMTADKHWEAAGMGPATETYLAGPDDLMRSDSRDFIEDPKGYRRSAIDA  360

Query  360  GTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDS  419
            GT  DVV+RAI+ G TTL+QPV T GLRAA+RG+TG +++TDY G+RELEAY+PL++P+S
Sbjct  361  GTPPDVVDRAIRLGTTTLVQPVDTAGLRAAKRGETGVISATDYLGNRELEAYSPLSIPNS  420

Query  420  DLHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQ  479
            DLHWSILATR++S+AFA +  FS+ LV+    +I  ICVAS+ +A A VRP+RRLE GT+
Sbjct  421  DLHWSILATRDNSDAFARLGRFSKTLVIAVAAMIFAICVASLFVAQAAVRPVRRLEEGTR  480

Query  480  KISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVV  539
            KIS+GDYE+NIPV+ RDEIGDLTAAFNEMSRNL  KEELLNEQR+ENDRLLL++MPE V+
Sbjct  481  KISSGDYEINIPVRHRDEIGDLTAAFNEMSRNLAIKEELLNEQRRENDRLLLALMPESVL  540

Query  540  ERYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVE  599
            +RYR GE+TIAQ+HQDV +++ADI+G+DE S+ +  +ELV  VD+L RQFDSAAE LGVE
Sbjct  541  QRYREGEETIAQKHQDVAIIYADIVGLDEFSNDVPEDELVATVDDLFRQFDSAAEALGVE  600

Query  600  RIRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVI  659
            RIRT HNGYLA CGV TPRLD+I R VDFALE+ RI+DRFN Q  + L LRVG+NTG+V+
Sbjct  601  RIRTFHNGYLASCGVVTPRLDSIHRAVDFALEIGRIIDRFNRQAAHQLGLRVGVNTGNVV  660

Query  660  SGLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGL  719
            SGLVGRSS+VYDMWG AVSLAYQMHSGSPQPG+YV+SQVYEAMRDV QF  AG+ISVGG+
Sbjct  661  SGLVGRSSLVYDMWGGAVSLAYQMHSGSPQPGVYVSSQVYEAMRDVRQFAPAGSISVGGV  720

Query  720  EEPIYRLSER  729
            ++ IYRL ER
Sbjct  721  DQAIYRLLER  730


>gi|254820709|ref|ZP_05225710.1| hypothetical protein MintA_12321 [Mycobacterium intracellulare 
ATCC 13950]
Length=727

 Score =  951 bits (2457),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 461/728 (64%), Positives = 571/728 (79%), Gaps = 5/728 (0%)

Query  3    SGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVYQS  62
            +G + + V   E  PA+   +  LR   RF  SIQSK+M++LL+ S+ S+  I  + Y +
Sbjct  2    AGRSTEPVPPDEQNPARTTWRR-LRALSRF--SIQSKVMLMLLVASLASLGVIGTVEYVA  58

Query  63   GRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLAD  122
             R +L  AA ER+TQ+R +QKRA+ETLFSDL++SLV+Y  G T +DAV  FTAGFDQLA+
Sbjct  59   ARNALLPAASERMTQMRAAQKRAIETLFSDLSDSLVVYSHGTTALDAVREFTAGFDQLAN  118

Query  123  ATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYT--APFTSDQ  180
            A + P QQ+A+V++Y  + I P+ER TG KL + A+LP++ AQ+YLQA+YT  A  +S+Q
Sbjct  119  APVDPGQQRALVDFYTKKLIEPIERDTGKKLALDAVLPSNNAQKYLQAHYTVAANRSSNQ  178

Query  181  DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI  240
                 DDAGDGSAWSAANA+FN YFREI TRF+Y DA+LLDTRGN+VY++ K   LGTN+
Sbjct  179  TGSTPDDAGDGSAWSAANARFNDYFREIATRFEYRDALLLDTRGNVVYSVKKSASLGTNV  238

Query  241  LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA  300
             TGPYR+SNLRDAY KA+ AN+VDF WITDF PYQ QLG P AWL AP+   G   GVLA
Sbjct  239  RTGPYRQSNLRDAYEKAMAANSVDFVWITDFAPYQAQLGQPIAWLTAPIGPPGNAAGVLA  298

Query  301  LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG  360
            LPLPI K+N+IMTAD+QW+AAGMG   ETYLAGPD LMRSDSRLFL+DP+ Y++  VAAG
Sbjct  299  LPLPIAKVNRIMTADKQWKAAGMGDTAETYLAGPDHLMRSDSRLFLEDPQRYKRDAVAAG  358

Query  361  TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD  420
            T    V+ AI++GGTTL+QPVAT  +RAA RG++GT+T T Y G REL AYAPL+VP+SD
Sbjct  359  TRPAAVDTAIRWGGTTLVQPVATAAVRAADRGESGTLTDTSYLGRRELAAYAPLSVPNSD  418

Query  421  LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK  480
            LHWSI+ATR  +EA A V S ++ LV+ T  ++ VICVA++L+A   VRPIRRL+ G Q+
Sbjct  419  LHWSIVATRETAEANARVMSLTQTLVITTTAMVFVICVAALLVAQIFVRPIRRLQAGAQE  478

Query  481  ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE  540
            I AG+Y+V IPV S DEIG+LTAAFNEMSRNLQ KEELL EQRKENDRLL S+MPEPV  
Sbjct  479  IGAGNYDVAIPVTSHDEIGELTAAFNEMSRNLQIKEELLGEQRKENDRLLGSLMPEPVAR  538

Query  541  RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER  600
            RYR GE TIAQEHQDVTV+FAD++G+DEIS  LSG ELV IVDEL+R+ DSAAE LG+E 
Sbjct  539  RYREGEHTIAQEHQDVTVIFADLVGLDEISGRLSGRELVGIVDELIRELDSAAESLGIEP  598

Query  601  IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS  660
            IRTLHNGYLA CG+  PRLD++ RTV+FA+EM+ I+ RFN +TG  L LR GINTG+VIS
Sbjct  599  IRTLHNGYLASCGLNFPRLDSVHRTVEFAVEMKDIIARFNARTGYHLALRAGINTGNVIS  658

Query  661  GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE  720
            GLVGRSS+VYDMWGAAV+LA+Q  S + Q GIYVTS+VYE M D+ QFT AGTI+VGG+E
Sbjct  659  GLVGRSSIVYDMWGAAVNLAHQTRSSTTQTGIYVTSKVYEVMHDIRQFTPAGTITVGGVE  718

Query  721  EPIYRLSE  728
            + I++LSE
Sbjct  719  QQIWKLSE  726


>gi|336457930|gb|EGO36921.1| family 3 adenylate cyclase [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=730

 Score =  950 bits (2456),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 468/709 (67%), Positives = 572/709 (81%), Gaps = 7/709 (0%)

Query  27   RRRPRFR-ASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRA  85
            RRRP     SIQSK+MV+LL++S+ S+  I  + Y + R +L+ AA ER+ QLRE+QKRA
Sbjct  22   RRRPGLSWISIQSKVMVMLLVSSLASLGVIGTVEYVAARNALQPAASERMVQLREAQKRA  81

Query  86   VETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPV  145
            +ETLFSDL++SLV+Y RG T ++AV  FTAGFDQLA+A + PAQQ+A+V++Y    I PV
Sbjct  82   IETLFSDLSDSLVVYSRGSTALEAVQAFTAGFDQLANAPVDPAQQRALVDFYTERLIKPV  141

Query  146  ERTTGDKLDITALLPTSPAQRYLQAYYT----APFTSDQDAMRLDDAGDGSAWSAANAQF  201
            ER TG KL + A+LP   AQRYLQA+YT     PF     A   DDAGDGSAWSAANA+F
Sbjct  142  ERDTGKKLALDAVLPADNAQRYLQAHYTVAAGGPFEGTGSAP--DDAGDGSAWSAANARF  199

Query  202  NSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGAN  261
            N YFREI TRF+Y DA+LLDTRGN+VY++ K   LGTNILTGPYR+SNLR AY KA+ AN
Sbjct  200  NDYFREIATRFEYRDALLLDTRGNVVYSVRKSASLGTNILTGPYRQSNLRGAYEKAMAAN  259

Query  262  AVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAA  321
            +V+F WITDF+PYQPQLG PTAWLVAP+ A G+  GVLALPLPI K+N+IMTAD+QW+AA
Sbjct  260  SVNFVWITDFQPYQPQLGQPTAWLVAPIGAPGRAAGVLALPLPIAKVNRIMTADKQWRAA  319

Query  322  GMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPV  381
            GMG   ETYLAGPD+LMRSDSRL L+DPE Y +  VAAGT  + V+ AI++GGTTL+QPV
Sbjct  320  GMGRTAETYLAGPDNLMRSDSRLILEDPERYARDAVAAGTPRNTVDTAIRWGGTTLVQPV  379

Query  382  ATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASF  441
            AT  +RAAQRG+TGTVT T Y G REL AYAPL++P+SDLHWSILATR  +EA A V S 
Sbjct  380  ATAAVRAAQRGETGTVTDTGYLGRRELAAYAPLSLPNSDLHWSILATRETAEANARVVSL  439

Query  442  SRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDL  501
            ++ LVL T  ++ VICVA++L+A   VRPIRRL+ G ++ISAG+Y+V IPV SRDEIG+L
Sbjct  440  TQTLVLTTTAMVFVICVAALLVAQMFVRPIRRLQAGAREISAGNYDVTIPVTSRDEIGEL  499

Query  502  TAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFA  561
            TAAFN+MSRNLQ K+ELL EQRKENDRLL S+MPEPV  RYR GEQTIAQEHQDVTV+FA
Sbjct  500  TAAFNDMSRNLQIKQELLGEQRKENDRLLASLMPEPVARRYREGEQTIAQEHQDVTVIFA  559

Query  562  DILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDN  621
            DI+G+DEIS+ LSG ELV +VDELVR+ DSAAE LGVE IRTLHNGYLA CG+  PRLD+
Sbjct  560  DIVGLDEISAKLSGRELVGVVDELVREIDSAAETLGVEPIRTLHNGYLASCGLNVPRLDS  619

Query  622  IPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAY  681
            + RTV+FA+E++ I+ RFN +TG  L LR GINTG+V+SGLVGRSS+VYDMWGAAV+LA+
Sbjct  620  VQRTVEFAVEVQGIIARFNGRTGYHLGLRAGINTGNVVSGLVGRSSLVYDMWGAAVNLAH  679

Query  682  QMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSERS  730
            Q  S + Q GIYVTS+V E MRD+  FT AGT++VGG+E+ I++LSER+
Sbjct  680  QTRSSTTQTGIYVTSKVCEVMRDIRHFTPAGTVTVGGVEQQIWQLSERT  728


>gi|342860844|ref|ZP_08717494.1| hypothetical protein MCOL_18273 [Mycobacterium colombiense CECT 
3035]
 gi|342131868|gb|EGT85125.1| hypothetical protein MCOL_18273 [Mycobacterium colombiense CECT 
3035]
Length=726

 Score =  949 bits (2453),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 449/694 (65%), Positives = 564/694 (82%), Gaps = 0/694 (0%)

Query  35   SIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLT  94
            SIQSK+M++LL++S+ S+  I  + Y + R +L  AA ER+TQLR SQKRA+ETLFSDL+
Sbjct  29   SIQSKVMLMLLVSSLASLGVIGTVEYVAARNALLPAATERMTQLRASQKRAIETLFSDLS  88

Query  95   NSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDKLD  154
            +SLV+Y RG+T  +AV  FT+GFDQLA+A + P QQQA+V++YN   I P+ER TG+KL 
Sbjct  89   DSLVVYSRGMTAFEAVQAFTSGFDQLANAPVDPGQQQALVDFYNERLIKPLERDTGNKLA  148

Query  155  ITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDY  214
            + A+LP++ AQ+YLQA+YT       +    DDAGDGSAWSAANA+FN YFREI TRF+Y
Sbjct  149  LDAVLPSNNAQKYLQAHYTVAAHGSSNGSAPDDAGDGSAWSAANARFNDYFREIATRFEY  208

Query  215  DDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFKPY  274
             DA+LLDTRGN+VYT+ K   LGTN+LTGPYR+SNLR AY KA+ AN+++F WITDF+PY
Sbjct  209  QDAMLLDTRGNVVYTVRKSASLGTNVLTGPYRQSNLRGAYEKAMAANSLNFVWITDFQPY  268

Query  275  QPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGP  334
            QPQLG P AWLVAP+ + G+  GVLALPLPI  +N+IMTAD+QW+AAGMG   ETYLAGP
Sbjct  269  QPQLGHPIAWLVAPIGSPGRPIGVLALPLPIATVNRIMTADQQWRAAGMGRTAETYLAGP  328

Query  335  DSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQT  394
            DSLMRSDSR+FL+D E YR++ +AAG   + V+ AI++GGTTL+QPVAT  +RAAQRG+T
Sbjct  329  DSLMRSDSRVFLEDRERYRREALAAGVRRETVDTAIKWGGTTLVQPVATAAVRAAQRGET  388

Query  395  GTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTVGIIV  454
            GTVT T Y G +EL +YAPL++P+SDLHWSI+ATR  SEA A VAS ++ L+L T  ++ 
Sbjct  389  GTVTDTGYLGRKELMSYAPLSLPNSDLHWSIVATRETSEANARVASLTQTLILTTAAMVF  448

Query  455  VICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQT  514
            VICVA++L+A   VRPIRRL+ G ++I AG+Y+V+IPV SRDEIG+L AAFN+MSRNLQ 
Sbjct  449  VICVAALLVAQIFVRPIRRLQAGAREIGAGNYDVSIPVTSRDEIGELMAAFNDMSRNLQI  508

Query  515  KEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEISSGLS  574
            KEELL EQRKENDRLL S+MPEPV  RYR GEQTI+QEHQDVTV+FADI+G+DEIS  +S
Sbjct  509  KEELLTEQRKENDRLLASLMPEPVARRYRDGEQTISQEHQDVTVIFADIVGLDEISGKIS  568

Query  575  GNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRR  634
            G ELV IVD+L+R+ DSAAE LG+E IRTLHNGYLA CG+  PRLD++ RTV+FA+EM+ 
Sbjct  569  GRELVGIVDQLIRELDSAAESLGIEPIRTLHNGYLASCGLNFPRLDSVHRTVEFAVEMQD  628

Query  635  IVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYV  694
            I+ RFN +TG  L LR GINTG VISGLVGRSS+VYDMWGAAV+LA+Q  S + Q GIYV
Sbjct  629  IIARFNSKTGYHLALRAGINTGHVISGLVGRSSIVYDMWGAAVNLAHQTRSSTTQSGIYV  688

Query  695  TSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSE  728
            T+QVYE M D+ +FT AGTI+VGG+E+ I++LSE
Sbjct  689  TAQVYEVMHDIRRFTPAGTITVGGVEQQIWKLSE  722


>gi|254775649|ref|ZP_05217165.1| hypothetical protein MaviaA2_13405 [Mycobacterium avium subsp. 
avium ATCC 25291]
Length=730

 Score =  948 bits (2451),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 467/709 (66%), Positives = 571/709 (81%), Gaps = 7/709 (0%)

Query  27   RRRPRFR-ASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRA  85
            RRRP     SIQSK+MV+LL++S+ S+  I  + Y + R +L+ AA ER+ QLRE+QKRA
Sbjct  22   RRRPGLSWISIQSKVMVMLLVSSLASLGVIGTVEYVAARNALQPAASERMVQLREAQKRA  81

Query  86   VETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPV  145
            +ETLFSDL++SLV+Y RG T ++AV  FTAGFDQLA+A + PAQQ+A+V++Y    I P 
Sbjct  82   IETLFSDLSDSLVVYSRGSTALEAVQAFTAGFDQLANAPVDPAQQRALVDFYTERLIKPF  141

Query  146  ERTTGDKLDITALLPTSPAQRYLQAYYT----APFTSDQDAMRLDDAGDGSAWSAANAQF  201
            ER TG KL + A+LP   AQRYLQA+YT     PF     A   DDAGDGSAWSAANA+F
Sbjct  142  ERDTGKKLALDAVLPADNAQRYLQAHYTVAAGGPFEGTGSAP--DDAGDGSAWSAANARF  199

Query  202  NSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGAN  261
            N YFREI TRF+Y DA+LLDTRGN+VY++ K   LGTNILTGPYR+SNLR AY KA+ AN
Sbjct  200  NDYFREIATRFEYRDALLLDTRGNVVYSVRKSASLGTNILTGPYRQSNLRGAYEKAMAAN  259

Query  262  AVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAA  321
            +V+F WITDF+PYQPQLG PTAWLVAP+ A G+  GVLALPLPI K+N+IMTAD+QW+AA
Sbjct  260  SVNFVWITDFQPYQPQLGQPTAWLVAPIGAPGRAAGVLALPLPIAKVNRIMTADKQWRAA  319

Query  322  GMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPV  381
            GMG   ETYLAGPD+LMRSDSRL L+DPE Y +  VAAGT  + V+ AI++GGTTL+QPV
Sbjct  320  GMGRTAETYLAGPDNLMRSDSRLILEDPERYARDAVAAGTPRNTVDTAIRWGGTTLVQPV  379

Query  382  ATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASF  441
            AT  +RAAQRG+TGTVT T Y G REL AYAPL++P+SDLHWSILATR  +EA A V S 
Sbjct  380  ATAAVRAAQRGETGTVTDTGYLGRRELAAYAPLSLPNSDLHWSILATRETAEANARVVSL  439

Query  442  SRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDL  501
            ++ LVL T  ++ VICVA++L+A   VRPIRRL+ G ++ISAG+Y+V IPV SRDEIG+L
Sbjct  440  TQTLVLTTTAMVFVICVAALLVAQMFVRPIRRLQAGAREISAGNYDVTIPVTSRDEIGEL  499

Query  502  TAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFA  561
            TAAFN+MSRNLQ K+ELL EQ KENDRLL S+MPEPV  RYR GEQTIAQEHQDVTV+FA
Sbjct  500  TAAFNDMSRNLQIKQELLGEQCKENDRLLASLMPEPVARRYREGEQTIAQEHQDVTVIFA  559

Query  562  DILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDN  621
            DI+G+DEIS+ LSG ELV +VDELVR+ DSAAE LGVE IRTLHNGYLA CG+  PRLD+
Sbjct  560  DIVGLDEISAKLSGRELVGVVDELVREIDSAAETLGVEPIRTLHNGYLASCGLNVPRLDS  619

Query  622  IPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAY  681
            + RTV+FA+E++ I+ RFN +TG  L LR GINTG+V+SGLVGRSS+VYDMWGAAV+LA+
Sbjct  620  VQRTVEFAVEVQGIIARFNGRTGYHLGLRAGINTGNVVSGLVGRSSLVYDMWGAAVNLAH  679

Query  682  QMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSERS  730
            Q  S + Q GIYVTS+VYE MRD+  FT AGT++VGG+E+ I++LSER+
Sbjct  680  QTRSSTTQTGIYVTSKVYEVMRDIRHFTPAGTVTVGGVEQQIWQLSERT  728


>gi|41407377|ref|NP_960213.1| hypothetical protein MAP1279c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41395729|gb|AAS03596.1| hypothetical protein MAP_1279c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=730

 Score =  947 bits (2448),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 467/709 (66%), Positives = 571/709 (81%), Gaps = 7/709 (0%)

Query  27   RRRPRFR-ASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRA  85
            RRRP     SIQSK+MV+LL++S+ S+  I  + Y + R +L+ AA ER+ QLRE+QKRA
Sbjct  22   RRRPGLSWISIQSKVMVMLLVSSLASLGVIGTVEYVAARNALQPAASERMVQLREAQKRA  81

Query  86   VETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPV  145
            +ETLFSDL++SLV+Y RG T ++AV  FTAGFDQLA+A + PAQQ+A+V++Y    I PV
Sbjct  82   IETLFSDLSDSLVVYSRGSTALEAVQAFTAGFDQLANAPVDPAQQRALVDFYTERLIKPV  141

Query  146  ERTTGDKLDITALLPTSPAQRYLQAYYT----APFTSDQDAMRLDDAGDGSAWSAANAQF  201
            ER TG KL + A+LP   AQRYLQA+YT     PF     A   DDAGDGSAWSAANA+F
Sbjct  142  ERDTGKKLALDAVLPADNAQRYLQAHYTVVAGGPFEGTGSAP--DDAGDGSAWSAANARF  199

Query  202  NSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGAN  261
            N YFREI TRF+Y DA+LLDTRGN+VY++ K   LGTNILTGPYR+SNLR AY KA+ AN
Sbjct  200  NDYFREIATRFEYRDALLLDTRGNVVYSVRKSASLGTNILTGPYRQSNLRGAYEKAMAAN  259

Query  262  AVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAA  321
            +V+F WITDF+PYQPQLG PTAWLVAP+ A G+  GVLALPLPI K+N+IMTAD+QW+AA
Sbjct  260  SVNFVWITDFQPYQPQLGQPTAWLVAPIGAPGRAAGVLALPLPIAKVNRIMTADKQWRAA  319

Query  322  GMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPV  381
            GMG   ETYLAGPD+LMRS SRL L+DPE Y +  VAAGT  + V+ AI++GGTTL+QPV
Sbjct  320  GMGRTAETYLAGPDNLMRSASRLILEDPERYARDAVAAGTPRNTVDTAIRWGGTTLVQPV  379

Query  382  ATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASF  441
            AT  +RAAQRG+TGTVT T Y G REL AYAPL++P+SDLHWSILATR  +EA A V S 
Sbjct  380  ATAAVRAAQRGETGTVTDTGYLGRRELAAYAPLSLPNSDLHWSILATRETAEANARVVSL  439

Query  442  SRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDL  501
            ++ LVL T  ++ VICVA++L+A   VRPIRRL+ G ++ISAG+Y+V IPV SRDEIG+L
Sbjct  440  TQTLVLTTTAMVFVICVAALLVAQMFVRPIRRLQAGAREISAGNYDVTIPVTSRDEIGEL  499

Query  502  TAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFA  561
            TAAFN+MSRNLQ K+ELL EQRKENDRLL S+MPEPV  RYR GEQTIAQEHQDVTV+FA
Sbjct  500  TAAFNDMSRNLQIKQELLGEQRKENDRLLASLMPEPVARRYREGEQTIAQEHQDVTVIFA  559

Query  562  DILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDN  621
            DI+G+DEIS+ LSG ELV +VDELVR+ DSAAE LGVE IRTLHNGYLA CG+  PRLD+
Sbjct  560  DIVGLDEISAKLSGRELVGVVDELVREIDSAAETLGVEPIRTLHNGYLASCGLNVPRLDS  619

Query  622  IPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAY  681
            + RTV+FA+E++ I+ RFN +TG  L LR GINTG+V+SGLVGRSS+VYDMWGAAV+LA+
Sbjct  620  VQRTVEFAVEVQGIIARFNGRTGYHLGLRAGINTGNVVSGLVGRSSLVYDMWGAAVNLAH  679

Query  682  QMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSERS  730
            Q  S + Q GIYVTS+V E MRD+  FT AGT++VGG+E+ I++LSER+
Sbjct  680  QTRSSTTQTGIYVTSKVCEVMRDIRHFTPAGTVTVGGVEQQIWQLSERT  728


>gi|183983735|ref|YP_001852026.1| adenylate or guanylate cyclase [Mycobacterium marinum M]
 gi|183177061|gb|ACC42171.1| adenylate or guanylate cyclase [Mycobacterium marinum M]
Length=730

 Score =  921 bits (2380),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 436/729 (60%), Positives = 566/729 (78%), Gaps = 0/729 (0%)

Query  1    LTSGEALDSVAESESTPAKKRHKNVLRRRPRFRASIQSKLMVLLLLTSIVSVAAIAAIVY  60
            +TSG+  + V  + S    +      R     R  IQ+KL+V LL+ SI+SVA +  I Y
Sbjct  1    MTSGQPTEPVTAAASGQTGRTDSRGRRLLRFLRVGIQAKLLVTLLVCSILSVAVVGVIGY  60

Query  61   QSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQL  120
             SGR +L+  A ERL QLRE+QKR VE LFS+LT S+++Y  G++  +A   FT GF QL
Sbjct  61   VSGRNALQRVAVERLLQLREAQKRQVEALFSELTKSVMVYSNGMSANEATAAFTDGFAQL  120

Query  121  ADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQ  180
            A+AT+ P QQQAIV+YY NE I P+++ TG +LD+ A+LP SPAQ YLQAYYTAPF+S  
Sbjct  121  ANATVDPVQQQAIVDYYVNELIKPIDQATGHELDLEAVLPASPAQTYLQAYYTAPFSSSS  180

Query  181  DAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNI  240
            ++MR ++AGDGSAWSAANA+FN +FR IVTRF Y DA+LLD +GN+VY+++K PDLGTN+
Sbjct  181  ESMRFNNAGDGSAWSAANARFNDFFRGIVTRFQYRDALLLDLQGNVVYSVNKGPDLGTNL  240

Query  241  LTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLA  300
             TGPYRE+NLR AY KAL +N +DF WITDF+ YQP++  PTAWLV+PV   GK QGV+A
Sbjct  241  FTGPYRETNLRTAYQKALASNEIDFVWITDFQRYQPEVDAPTAWLVSPVGVDGKLQGVMA  300

Query  301  LPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAG  360
            L LP   +N+IM A+ +W+A GMG  TETYLAG D+LMRSDSRLFL+ P+EYR++ +A G
Sbjct  301  LALPPTNLNQIMNANEKWEAVGMGRSTETYLAGSDNLMRSDSRLFLESPDEYRREALAGG  360

Query  361  TSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSD  420
            T  DVVN+AI+ G T L+QPV + GLRAA RGQ+G    TDY G+RELEAYAPL+VP+SD
Sbjct  361  TREDVVNKAIRLGTTVLVQPVPSAGLRAALRGQSGITKDTDYLGNRELEAYAPLDVPNSD  420

Query  421  LHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQK  480
            L W+ILATR+D +A+  ++SF R +VL   GI + ICV SM++A  +VRPIRRLE GT+K
Sbjct  421  LRWAILATRDDWDAYERLSSFGRTVVLAVAGITLFICVVSMVLAKLLVRPIRRLEAGTEK  480

Query  481  ISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVE  540
            I +GDYEV +PVKSRDE+GDLTAAFNEMS NL+ K++LL EQR +N++LLL++MPEPVV+
Sbjct  481  IRSGDYEVTVPVKSRDELGDLTAAFNEMSSNLKVKDQLLTEQRSQNEQLLLALMPEPVVQ  540

Query  541  RYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVER  600
            RYR G + IA+EHQDVTV+FA+++G++EIS GLSG+ELV IVDEL RQFDSAA+ LGVE 
Sbjct  541  RYRAGGEVIAEEHQDVTVIFAELIGLEEISDGLSGDELVGIVDELFRQFDSAAQSLGVEP  600

Query  601  IRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVIS  660
            IRT HNGYLA CG TTPRLDN+ R ++FALE+  IV+RF  Q+ + L +RVG+ TG V+S
Sbjct  601  IRTFHNGYLAACGATTPRLDNVHRGIEFALEIELIVNRFANQSQHPLRVRVGVTTGRVVS  660

Query  661  GLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLE  720
            GLVGRS++ YDMWG AV +AY+M      PGIYV+++V++AMR++W FT AG ISV G +
Sbjct  661  GLVGRSNLAYDMWGGAVQMAYRMLGHLSDPGIYVSARVHDAMREIWTFTPAGAISVRGSQ  720

Query  721  EPIYRLSER  729
            + I+++SER
Sbjct  721  QQIWQVSER  729


>gi|118618964|ref|YP_907296.1| adenylate or guanylate cyclase [Mycobacterium ulcerans Agy99]
 gi|118571074|gb|ABL05825.1| adenylate or guanylate cyclase [Mycobacterium ulcerans Agy99]
Length=703

 Score =  902 bits (2332),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 425/700 (61%), Positives = 551/700 (79%), Gaps = 1/700 (0%)

Query  31   RF-RASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETL  89
            RF R  I +KL+V LL+ SI+SVA +  I Y SGR +L+  A ERL QLRE+QKR VE L
Sbjct  3    RFLRVGIPAKLLVTLLVCSILSVAVVGVIGYVSGRNALQRVAVERLHQLREAQKRQVEAL  62

Query  90   FSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTT  149
            FS+LT S+++Y  G++  +A    T GF QLA+AT+ P QQQAIV+YY NE I P+++ T
Sbjct  63   FSELTKSVMVYSNGMSANEATAALTDGFAQLANATVDPVQQQAIVDYYVNELIKPIDQAT  122

Query  150  GDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIV  209
            G +LD+ A+L  SPAQ YLQAYYTAPF+S  ++MR ++AGDGSAWSAANA+FN +FR IV
Sbjct  123  GHELDLEAVLSASPAQTYLQAYYTAPFSSSSESMRFNNAGDGSAWSAANARFNDFFRGIV  182

Query  210  TRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWIT  269
            TRF Y DA+LLD +GN+VY++++ PDLGTN+ TGPYRE+NLR AY KAL +N +DF WIT
Sbjct  183  TRFQYRDALLLDLQGNVVYSVNEGPDLGTNLFTGPYRETNLRTAYQKALASNEIDFVWIT  242

Query  270  DFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTET  329
            DF+ YQP++  PTAWLV+PV   GK QGV+AL LP   +N+IM A+ +W+A GMG  TET
Sbjct  243  DFQRYQPEVDAPTAWLVSPVGVDGKLQGVMALALPPTNLNQIMNANEKWEAVGMGRSTET  302

Query  330  YLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAA  389
            YLAG D+LMRSDSRLFL+ P+EYR++ +A GT  DVVN+A+  G T L+QPV + GLRAA
Sbjct  303  YLAGSDNLMRSDSRLFLESPDEYRREALAGGTREDVVNKAMWLGTTVLVQPVPSAGLRAA  362

Query  390  QRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVT  449
             RGQ+G    TDY G+RELEAYAPL+VP+SDL W+ILATR+D +A+  ++SF R +VL  
Sbjct  363  LRGQSGITKDTDYLGNRELEAYAPLDVPNSDLRWAILATRDDWDAYERLSSFGRTVVLAV  422

Query  450  VGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMS  509
             GI + ICV SM++A  +VRPIRRLE GT+KI +GDYEV +PVKSRDE+GDLTAAFNEMS
Sbjct  423  AGITLFICVVSMVLAKLLVRPIRRLEAGTEKIRSGDYEVTVPVKSRDELGDLTAAFNEMS  482

Query  510  RNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEI  569
             NL+ K++LL EQR +N++LLL++MPEPVV+RYR   + IA+EHQDVTV+FA+++G++EI
Sbjct  483  SNLKVKDQLLTEQRSQNEQLLLALMPEPVVQRYRADGEVIAEEHQDVTVIFAELIGLEEI  542

Query  570  SSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFA  629
            S GLSG+ELV IVDEL RQFDSAA+ LGVE IRT HNGYLA CG TTPRLDN+ R ++FA
Sbjct  543  SDGLSGDELVGIVDELFRQFDSAAQSLGVEPIRTFHNGYLAACGATTPRLDNVHRGIEFA  602

Query  630  LEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQ  689
            LE+  IV+RF  Q+ + L +RVG+ TG V+SG VGRS++ YDMWG AV +AY+M      
Sbjct  603  LEIELIVNRFANQSQHPLRVRVGVTTGRVVSGRVGRSNLAYDMWGGAVQMAYRMLGHLSD  662

Query  690  PGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSER  729
            PGIYV+++V++AMR++W FT AG ISV G ++ I+++SER
Sbjct  663  PGIYVSARVHDAMREIWTFTPAGAISVRGSQQQIWQVSER  702


>gi|333990119|ref|YP_004522733.1| adenylate or guanylate cyclase [Mycobacterium sp. JDM601]
 gi|333486087|gb|AEF35479.1| adenylate or guanylate cyclase [Mycobacterium sp. JDM601]
Length=721

 Score =  894 bits (2310),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 435/720 (61%), Positives = 559/720 (78%), Gaps = 5/720 (0%)

Query  12   ESESTPAKKRHKNVLRRRPRF--RASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRA  69
            ES  + A     NV RRR     R SIQ+KLM++LLLTSIVSV  +  + +Q G   L+ 
Sbjct  2    ESAPSAAADDTANVERRRRWLPSRLSIQTKLMLILLLTSIVSVGVVGFVEFQYGAAELQR  61

Query  70   AAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQ  129
            +A  +L Q RE+Q+RAV +LF+++T+SL+I+  G    +A+  FTAGFD+LA AT++P Q
Sbjct  62   SATSKLVQAREAQRRAVSSLFAEMTSSLIIFSGGAMASNALHAFTAGFDELARATVTPEQ  121

Query  130  QQAIVNYYNNEFITPVERTTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAG  189
            Q+AIV +Y + FI  +   TG++ DI ALLP S AQRYLQA+YTA +T + D  + +DAG
Sbjct  122  QRAIVGHYRDNFIEQLAERTGERADIAALLPASTAQRYLQAHYTAGYTGESD--KPEDAG  179

Query  190  DGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESN  249
            DGSAWSAANA+FNS+F EIV R +Y DA+LLDTRGN+VY+ +K  DLGTN+LTGPYRES 
Sbjct  180  DGSAWSAANAEFNSFFAEIVKRNEYLDALLLDTRGNVVYSANKGVDLGTNVLTGPYRESV  239

Query  250  LRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKIN  309
            LRDAY KAL +NAV+F WITD++PYQP L  PTAWLV+PV   G  +GVLALPLP  K+N
Sbjct  240  LRDAYRKALASNAVNFVWITDYQPYQPNLDTPTAWLVSPVGVKGTVEGVLALPLPSAKVN  299

Query  310  KIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRA  369
            +IMTA+R W+AA +G  TETYLAGPD LMRSDSRLFL+DPE YR + VAAGT +  V+RA
Sbjct  300  RIMTANRDWKAAQVGRTTETYLAGPDDLMRSDSRLFLEDPERYRSEAVAAGTPVATVDRA  359

Query  370  IQFGGTTLLQPVATEGLRAAQRGQTGTV-TSTDYTGSRELEAYAPLNVPDSDLHWSILAT  428
            ++ G TTL+QPV++ GLRAAQRGQTGT+ T  DY G+REL AYAPL +P+SDL WSILAT
Sbjct  360  LKLGTTTLVQPVSSPGLRAAQRGQTGTLNTGYDYLGNRELAAYAPLTIPNSDLQWSILAT  419

Query  429  RNDSEAFAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEV  488
            R+ S+A+A V SFS+ +VL T G+IV ICV +ML+A   +RPIRRL+   Q+ISAGDY  
Sbjct  420  RDYSDAYAGVTSFSKRVVLATTGVIVAICVLAMLLARLFLRPIRRLQAAAQRISAGDYTA  479

Query  489  NIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQT  548
             +P  + DEIGDLT AFN+M R+L+TKEELLNEQRK+ND LLLS+MPE VV RYR GEQ 
Sbjct  480  AVPSGTADEIGDLTKAFNDMGRSLRTKEELLNEQRKQNDELLLSLMPESVVRRYRGGEQA  539

Query  549  IAQEHQDVTVLFADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGY  608
            IA+EH +V+V++A++ G+D++S  ++ NELV +VDELVRQFD+AAE +GVERIRT++NGY
Sbjct  540  IAEEHHNVSVVYAELQGIDQLSGEVAANELVTVVDELVRQFDAAAEVVGVERIRTMYNGY  599

Query  609  LAGCGVTTPRLDNIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSV  668
            LAGCG+TTPRLD + R V+FA EM+RIVDRFN ++G+ L L  G+NTG+V+SGLVGRS V
Sbjct  600  LAGCGLTTPRLDGVHRIVEFASEMQRIVDRFNVKSGHRLSLWAGVNTGEVVSGLVGRSGV  659

Query  669  VYDMWGAAVSLAYQMHSGSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSE  728
             YD+WG+AV+LAYQ+  G+PQ GIYVT  V + +    +FT AGT+++G  EE  +RLSE
Sbjct  660  TYDLWGSAVNLAYQLRRGTPQSGIYVTGAVRDMLGGGGEFTPAGTVAIGDTEEQAWRLSE  719


>gi|118469724|ref|YP_887881.1| cyclase [Mycobacterium smegmatis str. MC2 155]
 gi|118171011|gb|ABK71907.1| putative cyclase [Mycobacterium smegmatis str. MC2 155]
Length=705

 Score =  876 bits (2264),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 421/703 (60%), Positives = 539/703 (77%), Gaps = 9/703 (1%)

Query  33   RASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSD  92
            R SIQSKL+ +LL+TS++S A +  I YQSGR+SLR + ++RLT++R +Q R +ET F  
Sbjct  4    RISIQSKLLAMLLVTSVLSAAVVGFIGYQSGRSSLRDSVFDRLTEIRTAQARQLETQFRS  63

Query  93   LTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTT---  149
              NSLVIY RG T ++A   FTAGFDQL DATISPAQQ+AI ++Y N+F    E +    
Sbjct  64   FRNSLVIYTRGTTAIEAARAFTAGFDQLGDATISPAQQKAITDWYENQFSATTEHSDAAD  123

Query  150  ---GDKLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFR  206
               G+++D+ ALLP+S  Q+YLQA YTAPFT    A+  DDAGDGS WSAANA FN +FR
Sbjct  124  NLDGNEVDVEALLPSSNPQKYLQALYTAPFTDWDKAIENDDAGDGSGWSAANALFNGFFR  183

Query  207  EIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFT  266
            EIVTR  +DDA+LLDTRGN+VYT  K  DLGTNI TGPY+   L +AY +AL +N VD+ 
Sbjct  184  EIVTRSGFDDALLLDTRGNVVYTAYKGSDLGTNIYTGPYKGGELSEAYREALNSNTVDYV  243

Query  267  WITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSG  326
             +TDF  YQP  G PTAW+V+P+  GG+ +GVLAL  PI  +N++MT D +W+ +G+G  
Sbjct  244  AVTDFGIYQPS-GTPTAWMVSPIGGGGRIEGVLALQFPISVVNQLMTMDGKWEESGLGET  302

Query  327  TETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGL  386
             ETYL GPD LMRSDSRLFL++PE+++  V+ AGT   V  ++I  GGTTL+QPV+ E  
Sbjct  303  GETYLVGPDGLMRSDSRLFLENPEQFKADVIEAGTPPGVAEQSILHGGTTLVQPVSDEAS  362

Query  387  RAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALV  446
            + A +GQ+G++   DY G   L+AYAPL++  + L WS++A  + +EAFA V  F+R LV
Sbjct  363  KLAGQGQSGSIIERDYLGQETLQAYAPLDL--TGLDWSVVAKIDTAEAFAPVTKFTRTLV  420

Query  447  LVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFN  506
            L TV +I  +C+A++L+A   VRPIRRLE G Q+ISAGDY V +PV SRDE GDLT AFN
Sbjct  421  LSTVAMIFAVCIAAILLARVFVRPIRRLEAGAQQISAGDYGVALPVVSRDEFGDLTVAFN  480

Query  507  EMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGV  566
            EMSRNL+ KE+LL+EQRKENDRLLLS+MPEPVV+RYR GE+TIAQ+HQ+VTVLFAD++G+
Sbjct  481  EMSRNLRIKEDLLDEQRKENDRLLLSLMPEPVVQRYREGEETIAQDHQNVTVLFADLMGL  540

Query  567  DEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTV  626
            D +S+ +S +E + IV++LVRQFD+AAE LGVER+RTLHNGYLA CG+T PRLDN+ RTV
Sbjct  541  DRLSASMSSDEHLSIVNKLVRQFDAAAESLGVERVRTLHNGYLASCGLTVPRLDNVRRTV  600

Query  627  DFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSG  686
            DFA EM+RIVDRF  +TG DL LR GI+TG V SGLVGRSS+ YDMWGAAV LAYQ+  G
Sbjct  601  DFAFEMQRIVDRFRGETGYDLRLRAGIDTGTVSSGLVGRSSLAYDMWGAAVDLAYQVQRG  660

Query  687  SPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSER  729
             PQPG+YVT QV++A+RD+ QFTA G+++V G E PI+RLSER
Sbjct  661  MPQPGVYVTDQVHDAVRDIRQFTAVGSVTVDGTERPIWRLSER  703


>gi|229818726|ref|YP_002880252.1| adenylate/guanylate cyclase with integral membrane sensor [Beutenbergia 
cavernae DSM 12333]
 gi|229564639|gb|ACQ78490.1| adenylate/guanylate cyclase with integral membrane sensor [Beutenbergia 
cavernae DSM 12333]
Length=695

 Score =  583 bits (1503),  Expect = 3e-164, Method: Compositional matrix adjust.
 Identities = 306/698 (44%), Positives = 456/698 (66%), Gaps = 4/698 (0%)

Query  32   FRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFS  91
             R  IQSKL+V+LL  ++V+   +  I Y+SG  +L  AAY+++TQ+RES+ R V + F+
Sbjct  1    MRIEIQSKLLVMLLAMALVTALVVGWIGYRSGTQALEQAAYQQVTQVRESRAREVASYFT  60

Query  92   DLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGD  151
             L  ++V+  R  T  +++  F AG+  LA A +S  Q+  +   Y++  +  +    G 
Sbjct  61   GLERAVVLNSR--TAENSMQAFEAGWRDLAGAQVSADQRAQVEAVYSDVLLPQLAENAGQ  118

Query  152  KLDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTR  211
            +  + + LPTS A  YLQA+YT P       + +DDAGDGS WSAA+A+++   REIVT+
Sbjct  119  EFTVESFLPTSDAAWYLQAHYTDPALDYDATLAVDDAGDGSVWSAAHARYHDTLREIVTQ  178

Query  212  FDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDF  271
             +++D +L+D  GN+VY+  K  DLGTN+L+GPY   +L D + + + +N  D+  + DF
Sbjct  179  NEFEDLLLIDPDGNVVYSAYKGVDLGTNVLSGPYAGGSLEDTFRETVTSNGQDYVGLADF  238

Query  272  KPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYL  331
            +PYQP    PT ++++P++  G T GVLA+    D++N+++T+  QWQ AG G   ETYL
Sbjct  239  EPYQPLADSPTQFVMSPIQDDGLTVGVLAIQASTDRLNEVLTSGGQWQQAGFGETGETYL  298

Query  332  AGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQR  391
             GPD  +RS SRL +++PEEY  +VVAAGT  DV    ++ G   L Q V +  +  A  
Sbjct  299  VGPDGTLRSTSRLLVENPEEYVDRVVAAGTPRDVAETVVRLGNPILRQSVQSPAIERALD  358

Query  392  GQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTVG  451
            G+TG V +T Y  +  + AY P++ P   L+W I A  + SE FA V  F R LVL   G
Sbjct  359  GETGIVRTTGYRDTDVIVAYTPVDAPG--LNWVIAAAVDPSEVFAPVQDFQRQLVLSIAG  416

Query  452  IIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMSRN  511
            ++++  VAS+L+A   VRPIR L  G + +SAGD +  + V++ DE+GDL  AFNEM+ +
Sbjct  417  MLLLAAVASLLLAQVFVRPIRSLVSGVRAVSAGDLDAQVRVRTNDEVGDLAEAFNEMATS  476

Query  512  LQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEISS  571
            L+TK+ELL  ++ E DR+LLS+MP  V E+ + GE+TIAQ+ QDV+V+FAD++G    +S
Sbjct  477  LRTKQELLEAEQAEKDRILLSLMPPAVAEQVKGGEETIAQDFQDVSVVFADLVGFAGFTS  536

Query  572  GLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALE  631
            G+  +  ++ ++ELVR FD AAE  GVE++R+L NG+LA CG+  PR+D+  R V F  E
Sbjct  537  GMDSHAALEHLNELVRAFDEAAERTGVEKVRSLRNGFLASCGLVIPRVDHARRIVQFTSE  596

Query  632  MRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQPG  691
            +  +V  FN + G+DL LR GIN G V SG+VGR+SVVYD+WG AV LAY++H+  P+PG
Sbjct  597  LTEVVAAFNARHGSDLSLRAGINVGTVTSGIVGRASVVYDLWGEAVDLAYRVHAEEPEPG  656

Query  692  IYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRLSER  729
            IYVT ++Y+A+RD ++FT AG +     E P++RL ER
Sbjct  657  IYVTDRIYDAVRDQYEFTEAGVVRSSDGEHPVWRLDER  694


>gi|326332469|ref|ZP_08198745.1| putative adenylate cyclase [Nocardioidaceae bacterium Broad-1]
 gi|325949782|gb|EGD41846.1| putative adenylate cyclase [Nocardioidaceae bacterium Broad-1]
Length=751

 Score =  487 bits (1254),  Expect = 3e-135, Method: Compositional matrix adjust.
 Identities = 250/696 (36%), Positives = 412/696 (60%), Gaps = 12/696 (1%)

Query  36   IQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTN  95
            IQSKL+++L+LTS++S   +    Y+SG  +L  +   RL  + + +   V  + ++++ 
Sbjct  60   IQSKLLLMLVLTSVLSSIVVGYFGYRSGTQALEDSTRSRLQDVLDERASRVSAMINNVSG  119

Query  96   SLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDKLDI  155
             +++  +G+   +++  F+A +D+LA  T+ PA   A+  YYN+ +   ++   G +++ 
Sbjct  120  GVILDSQGVGP-ESMADFSAAYDELARGTVDPADTAALTRYYNDYYGPHLQENVGGEINA  178

Query  156  TALLPTSPAQRYLQAYYTAPFTSDQDAMR----LDDAGDGSAWSAANAQFNSYFREIVTR  211
             A +PTSPA+ YLQA YT   T++ D  R    +DDAGDGSAW+AAN ++N Y+R +   
Sbjct  179  EAFIPTSPARTYLQARYTVKATTETDTSRPVSDVDDAGDGSAWTAANKKWNPYWRAVRDS  238

Query  212  FDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDF  271
               DD +++DT G IVYT  K  DLG+++ TG  R+  L   + +AL +N  D+  I+D+
Sbjct  239  LGLDDVMMIDTEGRIVYTADKGSDLGSDVDTGELRDGALESLWREALRSNNRDYVAISDY  298

Query  272  KPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQ-AAGMGSGTETY  330
            + YQP  G P  ++ +P+  GG   GVL   +  + I  + T     +   G+G   E+Y
Sbjct  299  ESYQPAFGRPRMFVASPIGTGGDATGVLVYEVSSNAITSLTTGSGTAEKVTGLGETGESY  358

Query  331  LAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQ  390
            + G D L+R++SR  L DP+ + +++   GTS + V++ ++      L     +    A+
Sbjct  359  IVGTDGLLRTNSRELLADPKAFAERMRDNGTSEETVDKMLRMKLAVGLLSAGPDVSEVAK  418

Query  391  RGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTV  450
            +G TG    TDY G   L AY PL+V    L WS++AT    EA A V  F+R ++L T 
Sbjct  419  QGDTGVGEMTDYAGHEVLAAYEPLDV--EGLDWSLVATIETEEALAPVQGFARNVLLATA  476

Query  451  GIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMSR  510
             +I+++C  S+L+A    RP+ RL  G + ++ GD    +   SRDE GDL  AFN++S 
Sbjct  477  AVILLVCAISILLARVFTRPVGRLMKGVRAVAGGDLGAQVDAGSRDEFGDLATAFNDLSS  536

Query  511  NLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEIS  570
            +L  K+EL++ Q+ EN R+L S+MPE + +RY+ GE TI+ EHQ+ +V++ +I G D  +
Sbjct  537  SLAAKQELVDAQQAENSRILRSLMPEAIADRYQGGETTISAEHQNASVVYTEIDGFDSFA  596

Query  571  SGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFAL  630
                  E + ++ EL   FD+AA   G+E++R++  GY+   G+   R+D++ R  DFA+
Sbjct  597  GKRPAEESLAMLKELSAGFDAAAHRAGIEKVRSVGTGYIGSSGLIVQRVDHVRRVADFAV  656

Query  631  EMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQP  690
            ++ R+V+RFN   G  L LR G++TGDV  GLVG+  +VY++WG AV LAY++ + + + 
Sbjct  657  DVARMVERFNVTNGAQLVLRAGVHTGDVRGGLVGQGDMVYNLWGDAVDLAYRVRTVAGEA  716

Query  691  GIYVTSQVYEAMRDVWQFTAAGTISVGGLEEPIYRL  726
            GIYVT +V E +   + F   GTI     + P++R+
Sbjct  717  GIYVTDEVKEQLAAAYDFEQVGTIE----DSPVWRV  748


>gi|332709914|ref|ZP_08429870.1| adenylate cyclase, family 3 protein [Lyngbya majuscula 3L]
 gi|332351285|gb|EGJ30869.1| adenylate cyclase, family 3 protein [Lyngbya majuscula 3L]
Length=700

 Score =  479 bits (1234),  Expect = 6e-133, Method: Compositional matrix adjust.
 Identities = 255/683 (38%), Positives = 405/683 (60%), Gaps = 10/683 (1%)

Query  43   LLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYER  102
            +LL  S  S+   A I Y+SG++ L      +LT LR S+   +E+ F D+ +       
Sbjct  1    MLLALSTCSLFVTAYIGYRSGKSHLSKTVSNQLTSLRASKADQIESYFEDIRHQTQTLSE  60

Query  103  GLTVVDAVVRFTAGFDQLADA---TISPAQ-QQAIVNYYNNEFITPVERTTGDKLDITAL  158
             L VV+A+  F   ++QL  +   T +P   +  +  YY  EF+T +  T+  K  + + 
Sbjct  61   NLMVVEAMQEFKTAYNQLQQSRTPTDTPTDLEDTLKEYYRKEFLTKLAETSDGKPVLESY  120

Query  159  LPTSPAQRYLQAYYTA--PFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDD  216
            LP + A RYLQ YY A  P  + +  + LDD  D S +S+ + +++  FR IV +F Y D
Sbjct  121  LPETSAARYLQYYYIATNPNPAGEKHL-LDDPEDKSEYSSIHTRYHPIFRNIVEKFAYQD  179

Query  217  AVLLDTR-GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQ  275
             +L+D + G IVY++ K+ D GTN+ TGPY +SNL  A      A   D+  I DF  Y+
Sbjct  180  MLLIDPQTGEIVYSVFKETDFGTNLTTGPYSDSNLAFALGDLRKAKGKDYVQIFDFDSYR  239

Query  276  PQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPD  335
            P  G P A++ AP+  G K  GVLA  LP+++IN +MT  R+W++ G+G   E YL G D
Sbjct  240  PSFGAPVAFIAAPIYDGSKFIGVLAFQLPVNQINNVMTGYRKWKSNGLGDTGEIYLVGED  299

Query  336  SLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTG  395
             LMRS SR  +QDP  Y K +   G    ++ R  QFG + L QPV TE ++AA  GQ G
Sbjct  300  YLMRSVSRFLIQDPTAYSKALREQGVKEQILKRIEQFGTSILQQPVKTEAVKAALAGQEG  359

Query  396  TVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTVGIIVV  455
            T    DY G   L +YAPLN+    L W IL+  + +EA+A V +F + +++    II++
Sbjct  360  TQIINDYRGIEVLSSYAPLNI--DGLEWVILSEMDLAEAYAPVYAFQKRVLVSAALIILL  417

Query  456  ICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTK  515
            I + +M++AH  V+P+R L    +K++ G+ +  + + S DE G+L  +FN+M  +L+T+
Sbjct  418  ITLLAMVLAHLFVQPVRALIASARKVTDGEVDAVVNINSEDEFGELAESFNQMVGSLRTQ  477

Query  516  EELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEISSGLSG  575
             +L+ ++ +EN++LL S+ P+ V +R + GE  IA+   +VTVLF DI G  ++S  +  
Sbjct  478  TKLVEQKNRENEKLLTSVFPDSVAKRLKRGETNIAESVSNVTVLFCDIAGFGKLSRSMDT  537

Query  576  NELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALEMRRI  635
            +E++ I+++LV  FD A    G+E+I+T+ + Y+A CG++   +D+  R VDFALEM  +
Sbjct  538  HEVIAILNDLVSLFDQATAKYGIEKIKTIGDNYMAVCGLSILHIDHQKRAVDFALEMLAL  597

Query  636  VDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQPGIYVT  695
              RF+ + G D+ L +GI++GD+++G+VGR  VVYD+WG  V++A ++    P+  I V+
Sbjct  598  THRFSHERGFDIDLEIGIHSGDIVAGIVGREKVVYDVWGDTVNVANKLMFDCPRGAILVS  657

Query  696  SQVYEAMRDVWQFTAAGTISVGG  718
              VY ++ D++ F  A  I+  G
Sbjct  658  QNVYNSLHDIYDFEQAEDITPNG  680


>gi|158334574|ref|YP_001515746.1| cyclase [Acaryochloris marina MBIC11017]
 gi|158304815|gb|ABW26432.1| cyclase, putative [Acaryochloris marina MBIC11017]
Length=699

 Score =  479 bits (1233),  Expect = 8e-133, Method: Compositional matrix adjust.
 Identities = 246/687 (36%), Positives = 399/687 (59%), Gaps = 3/687 (0%)

Query  33   RASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSD  92
            + SIQSKL ++ L  S+ S+  IA I Y SG+  L    + +LT LR S+   V + F  
Sbjct  4    KLSIQSKLTLMFLGVSVSSILVIAFIGYNSGKAVLTRRIFNQLTSLRTSKSYEVRSFFDQ  63

Query  93   LTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDK  152
            L + +       T  +A+  F     +L    I    QQAI  YY  EFI P++     +
Sbjct  64   LNHQMRFLSDDPTTKEAMKAFRQAHQELKSQKIPSQWQQAIQAYYQKEFIQPLDANIDGE  123

Query  153  LDITALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTRF  212
              +   LP   +  YLQ +YT       + +++D+ GDGS ++  + +++  FR +V+ F
Sbjct  124  PQVQTYLPLGNSDVYLQYHYTIKTPDFDEKVKIDNPGDGSKYTQVHQRYHPTFRSLVSEF  183

Query  213  DYDDAVLLDTR-GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDF  271
             Y+D  L+D + G +VY+  K  D  T++ +GPY +S L  A+ + +      F   TDF
Sbjct  184  TYEDLFLIDPKSGKVVYSAYKGVDFSTDLESGPYSQSVLAQAFREVVRKGEPKFVTFTDF  243

Query  272  KPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYL  331
            +PY+P L  P A + +P+  GG+  GV+AL + I+KI+++MT  R+WQ  G+G   ETYL
Sbjct  244  EPYRPSLNSPAAIIASPLFEGGELIGVMALQVNINKIDEVMTNGRRWQDMGLGKSGETYL  303

Query  332  AGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQR  391
             GPD L+RS+SR  L++   Y + +  +G     + R  +   + L Q V T   + A  
Sbjct  304  VGPDFLLRSNSRFLLENSPSYFQSLTQSGLEASQIERMRRQKNSILEQEVKTVAAQRALL  363

Query  392  GQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTVG  451
            G +G     DY G   L +Y+ L V   D  W+ILA  +  EAFA +  F + +++ T  
Sbjct  364  GNSGIDIVNDYRGIPVLSSYSTLQVKGLD--WAILAEMDADEAFAPITEFQKQVLISTAI  421

Query  452  IIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMSRN  511
            +I+VI + ++L++   V+PI+ L  G +++S G+ +V + + S+DE  DL  +FN+M  +
Sbjct  422  LILVITILALLLSRLFVKPIQTLIAGFRQLSEGNTDVTVSMNSQDEFHDLAVSFNQMVES  481

Query  512  LQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEISS  571
            L  K + L  Q +EN++LL  ++PEPV +R + GE+ IA  + +VTVLFAD++G  +++ 
Sbjct  482  LSHKTQALEHQSQENEQLLSCILPEPVAQRLKSGEEQIADSYANVTVLFADLIGFTDLAE  541

Query  572  GLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFALE  631
             LS +E+V +++ELVR FD AAE  GVE+I+T+ +GY+A CG++ PRLD+  R +DF +E
Sbjct  542  ILSASEIVALLNELVRAFDEAAERFGVEKIKTIGSGYMAVCGLSVPRLDHTKRIMDFGIE  601

Query  632  MRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQPG  691
            + RIV RFN      L  RVGIN+G V++G+VGRS  +YD+WG  V++A++M +      
Sbjct  602  ITRIVQRFNQTHQTALKARVGINSGAVVAGIVGRSKFIYDLWGDTVNIAHRMQTAGKGDT  661

Query  692  IYVTSQVYEAMRDVWQFTAAGTISVGG  718
            + V+  V+  + D+++F     + + G
Sbjct  662  VQVSQSVHNQLGDIYEFENGREVEISG  688


>gi|307151657|ref|YP_003887041.1| integral membrane sensor-containing adenylate/guanylate cyclase 
[Cyanothece sp. PCC 7822]
 gi|306981885|gb|ADN13766.1| adenylate/guanylate cyclase with integral membrane sensor [Cyanothece 
sp. PCC 7822]
Length=724

 Score =  469 bits (1207),  Expect = 8e-130, Method: Compositional matrix adjust.
 Identities = 247/686 (37%), Positives = 398/686 (59%), Gaps = 4/686 (0%)

Query  33   RASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSD  92
            + SIQSKL+++LLL SI  +     + Y SG+T+     + +L  LR  + + +E+ F  
Sbjct  6    KLSIQSKLLLMLLLISIALIFITGYMDYSSGKTAFTKTIFNQLVILRSVRAKEIESYFQF  65

Query  93   LTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDK  152
              N ++      + ++A+  F A + +L   T++P QQQ +  YY N FI  +     D 
Sbjct  66   SKNQILTVSESPSAIEAMKTFKAAYQKLETQTLNPNQQQQLEKYYQNVFIPELGHNVVDG  125

Query  153  LDIT-ALLPTSPAQRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTR  211
              I    LP +   +YLQ +Y A   S Q    L++ GDGS +S  + +++  FR +  R
Sbjct  126  TPIAETYLPQTSVAQYLQYHYLAKNRSKQRQNDLENPGDGSEYSKVHQKYHPLFRNLQKR  185

Query  212  FDYDDAVLLDT-RGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITD  270
            F Y+D  L+D   GNIVY+  K  D  TNI  GPY  +NL  A L    +       I D
Sbjct  186  FKYNDIYLIDVDSGNIVYSAEKQVDFATNIGLGPYENTNLAKAILSIEKSRDHSLIIIKD  245

Query  271  FKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETY  330
            F+PY+P    P+A++   +  G +  G L   LPI+KIN IMT+  QW+  G+G   ETY
Sbjct  246  FEPYRPSYNKPSAFIATTIFDGTEFIGALVFQLPIEKINGIMTSSGQWEQTGLGQTGETY  305

Query  331  LAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQ  390
            L GPD+L+RS  R F+++P +Y + +   G   + + R  +     L+Q + +  L  A 
Sbjct  306  LVGPDNLLRSLPRQFVENPNQYYQALEKNGLDNNTIERIRRLNTPILVQKIESSALEQAI  365

Query  391  RGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTV  450
             G+ GT    DY G   L AY P+ V   D +W ++A  +  EAFA +  F+R L++ + 
Sbjct  366  TGKKGTAIYQDYRGIPVLAAYQPIQV--GDFNWGLIAQMSADEAFAPINEFTRQLLVTSA  423

Query  451  GIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMSR  510
             ++V     S  +A   VRPI++L  G  +I +G+ +V + ++S+DE G+L  AFN MS 
Sbjct  424  ILVVFFTPLSNWLARLFVRPIKQLRAGACRIGSGETDVKLNIQSKDEFGELAVAFNYMSE  483

Query  511  NLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEIS  570
            NL  +E L+ + ++EN+ LLL+++P+ + +RY+ GEQ IA    +VTVL+A+I G +E+S
Sbjct  484  NLHQRELLIQQMKQENENLLLNILPDLIAKRYKKGEQAIADTFPNVTVLYAEIEGFNELS  543

Query  571  SGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFAL  630
            + L   + +++++E+V  FD AAE  GVE++RT+ N Y+A CG++  R+D++ RTVDFAL
Sbjct  544  AELPPEQTIRLLNEIVSAFDEAAEAYGVEKMRTIGNLYVAVCGLSVARVDHVKRTVDFAL  603

Query  631  EMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQP  690
            ++ +++ RFN Q G  L L +GI+ G V+ G+VG++  +Y + G  + +AY +HS   Q 
Sbjct  604  DLLKLITRFNQQQGTKLSLDIGIHCGPVVGGIVGKTRFIYALTGETMRIAYAIHSSPRQN  663

Query  691  GIYVTSQVYEAMRDVWQFTAAGTISV  716
             I VT +VYE+++D++ F   G + +
Sbjct  664  VIQVTHKVYESVKDLYPFEQIGEVEI  689


>gi|126657175|ref|ZP_01728341.1| putative cyclase (adenylyl-or guanylyl-)(adenylate-or guanylate-) 
[Cyanothece sp. CCY0110]
 gi|126621446|gb|EAZ92157.1| putative cyclase (adenylyl-or guanylyl-)(adenylate-or guanylate-) 
[Cyanothece sp. CCY0110]
Length=712

 Score =  431 bits (1107),  Expect = 3e-118, Method: Compositional matrix adjust.
 Identities = 244/693 (36%), Positives = 380/693 (55%), Gaps = 13/693 (1%)

Query  33   RASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSD  92
            R SIQSKLM++LL  SI S+  I+ + Y SG+ ++    Y ++T+LR S+ R V++ F+ 
Sbjct  6    RLSIQSKLMLMLLAVSIASILVISYVGYTSGKEAILENIYYQITELRNSRARQVQSYFNY  65

Query  93   LTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDK  152
            + N  +      TV++A V FT  F+QL +  +S      +  +Y  EFI  ++      
Sbjct  66   VQNHAITLAEDPTVIEATVSFTDSFNQLENEEVSSNMISELWRFYEKEFIPRLQMNVDGN  125

Query  153  LDITALLPTSPAQRYLQAYYTA--PFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVT  210
              + +  P     RYLQ +Y    P+  D  + RLD A DGS +S  +  F+ +FR I T
Sbjct  126  PTVLSYFPKENIARYLQYHYLVKNPYDVDNKS-RLDMAQDGSKYSEIHQNFHKFFRSITT  184

Query  211  RFDYDDAVLLDTR-GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWIT  269
            RFDY +  L+D+  GNIVY++ KD    T+   GPY  S   + +             + 
Sbjct  185  RFDYRNLFLVDSETGNIVYSVHKDTGFATSFKDGPYAYSGAANLFETLQNNRERGAFEVI  244

Query  270  DFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTET  329
            DF  ++P  G P A++ +P+       G+L L LP+++IN+IMT + QW+  G+G   ET
Sbjct  245  DFTSFRPSYGQPVAFIGSPIFQQSNLVGILLLQLPVNEINRIMTGNFQWKKDGLGKTGET  304

Query  330  YLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAA  389
             L G D LMRS SR  +++P+ Y K++     S  ++ R  +     LLQ V T  +  A
Sbjct  305  ILVGSDYLMRSQSRFLVENPDTYFKELKKQNISDRIIQRIKENNSPILLQEVKTNSIEKA  364

Query  390  QRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVT  449
             +G+ G     DY G   L AYAPL + D +L W IL+    SEAF  +  F +  VLVT
Sbjct  365  LKGEEGLGILDDYRGVSSLVAYAPLKLSD-NLDWVILSKIYVSEAFEPIQIFGKR-VLVT  422

Query  450  VGIIV-VICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEM  508
              I+V ++ + S+ ++  +V PI RL  GT+KI++G   V + V S DE   L  AFN+M
Sbjct  423  SAILVPIVTILSLFLSRRLVMPIYRLISGTKKITSGQSNVVVTVPSDDEFCQLAGAFNKM  482

Query  509  SRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDE  568
            +R +  ++E L EQ ++ND LLL  +P P+V+R + GE+ IA +   VTVL A+I+G DE
Sbjct  483  ARTIDEEKEALEEQIRKNDALLLKTLPAPIVKRLKQGEEKIADKFPHVTVLSANIVGFDE  542

Query  569  ISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDF  628
                +S  E V ++++++  FD AA+   VE+I T+   YLA  G+  PRLD     ++ 
Sbjct  543  QCDLMSAEEAVGLLNDIISAFDDAAQRHDVEKISTVGTSYLAASGLFVPRLDRDKAVIEL  602

Query  629  ALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMH----  684
             LEM RIV  F+ +      +R+GI +G+VI GL+G+   +Y++ G    +A  +     
Sbjct  603  GLEMLRIVRAFSQEKHLKFEIRIGIYSGEVIGGLLGKQKFIYNLIGNTAKVARFLMIVNS  662

Query  685  -SGSPQPGIYVTSQVYEAMRDVWQFTAAGTISV  716
              G P   I ++  +YE +++ +QF   G I +
Sbjct  663  VEGKPN-SILISQNLYEPLQEFYQFFKMGEIDI  694


>gi|254425372|ref|ZP_05039090.1| Adenylate and Guanylate cyclase catalytic domain protein [Synechococcus 
sp. PCC 7335]
 gi|196192861|gb|EDX87825.1| Adenylate and Guanylate cyclase catalytic domain protein [Synechococcus 
sp. PCC 7335]
Length=699

 Score =  419 bits (1077),  Expect = 8e-115, Method: Compositional matrix adjust.
 Identities = 240/702 (35%), Positives = 402/702 (58%), Gaps = 11/702 (1%)

Query  30   PRF-RASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVET  88
            P F R SIQSKLM +LL  SI S+  IA   Y+SGR +L  +  ++LT LR ++ R +E 
Sbjct  2    PSFNRLSIQSKLMSMLLAVSIGSIIVIAYEGYRSGRKALAGSFEKQLTSLRAAKARQIEN  61

Query  89   LFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADAT--ISPAQQQAIVNYYNNEFITPVE  146
             F  L + + +Y    + ++A+  F++ +D + D +  I   +   + ++Y NEF+  + 
Sbjct  62   YFQRLRSEIQVYGSTPSTIEAMKAFSSAYDSVLDESDSIDVRRTNGLRDFYRNEFVPALV  121

Query  147  RTTGDKLDITALLPTSPAQRYLQAYYTAPFTSD-QDAMRLDDAGDGSAWSAANAQFNSYF  205
              TG  +D    LP++   RYLQ  Y     +   D    +   D + +S A+ +++  F
Sbjct  122  ERTGLAVDSDVYLPSTIVSRYLQFEYIVENPNPIGDKEEFEGPTDSTDYSQAHRRYHPIF  181

Query  206  REIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDF  265
            R++V    Y D  L+D +GN+VY++ K+ D  T++L G    SNL + Y  A   N+  +
Sbjct  182  RKVVEELGYYDLFLIDNQGNVVYSVEKEIDFATSLLFGA-ASSNLAEVYKDAQRQNS-GY  239

Query  266  TWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGS  325
              + DF+ Y P    P A++  P+  G +  GV+A+ L +D+IN++MT +++W A G+G 
Sbjct  240  VAMVDFEFYIPSYSAPAAFMATPIYDGVELVGVMAIQLSVDEINRVMTGNQRWVADGLGE  299

Query  326  GTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEG  385
              ET+L G DS+MRSDSR+ L+DP+ Y   + A  T  + + R  Q   + L Q V  + 
Sbjct  300  TGETFLVGEDSMMRSDSRVRLEDPDRYFAAIAATATDTEQIERIRQLETSILSQEVNNQA  359

Query  386  LRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRAL  445
            + +AQ GQ+G  T  +Y G   L AYAPL++   D  W I +  +++E FA V+ F+R +
Sbjct  360  IDSAQEGQSGIDTVINYLGEPVLSAYAPLDIRGVD--WVIASEVDEAEIFAPVSIFARRV  417

Query  446  VLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAF  505
            ++   G++ +I +AS+ +A A ++P+ RL  G ++++ G  EV + V + DE+G+LT AF
Sbjct  418  LISAAGLVFLITLASLWLARAFLKPVNRLSEGFRRLALGHQEVLVDVLADDELGELTKAF  477

Query  506  NEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILG  565
            N M +  +    L++++ +E + LLL+M P  V +R R GE  I  E + VTV+F ++L 
Sbjct  478  NHMVKKNRKTSALVSQKTQETEALLLNMFPASVAKRLRKGEDLIVDEAESVTVVFINVLN  537

Query  566  VDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRT  625
               ++  L   + ++++++LV+  D A E  GVE+I+T  + YLA  G++  RLD+  R 
Sbjct  538  FQHLTEELKPRKAIEVLNDLVKALDEATESHGVEKIKTTGSEYLAVSGLSVARLDHSKRI  597

Query  626  VDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHS  685
            +DFA E  +IV + N +   +L +R+G++TG V++G VG   ++YD+WG  V  A+ + S
Sbjct  598  IDFAAESLQIVAQVNREWKVNLKMRIGVHTGGVMAGTVGTQRLIYDVWGDTVVTAHHVQS  657

Query  686  GSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGGLEE-PIYRL  726
             +    IYVT  V   + D++ F    T  V   E  PI+R+
Sbjct  658  AAAPNSIYVTKAVVGRLSDLYDFEP--TFDVESRENLPIFRV  697


>gi|336036484|gb|AEH82415.1| putative cyclase (adenylyl-or guanylyl- )(adenylate-or guanylate-) 
[Sinorhizobium meliloti SM11]
Length=710

 Score =  392 bits (1008),  Expect = 1e-106, Method: Compositional matrix adjust.
 Identities = 229/693 (34%), Positives = 369/693 (54%), Gaps = 7/693 (1%)

Query  29   RPRFRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVET  88
            RP  R  +  KL  +L+L   ++V     + Y   R +L  A +++LT  R+++ R VE 
Sbjct  11   RP-VRWGLAVKLFTILVLLGAIAVLVTGVLGYFRARDALEKAVFDQLTAARQTKTRQVED  69

Query  89   LFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT  148
             F  +   L +       VDA   F    DQL  A   P  +Q +  +Y   FI  + R 
Sbjct  70   YFRTIDAELRLLASSKMAVDATREFRIVVDQLDRAGAPPELRQKVGTWYTENFIPGITRV  129

Query  149  TGDKLDITALLPTSPAQRYLQAYYTA--PFTSDQDAMRLDDAGDGSAWSAANAQFNSYFR  206
             G K  +   LP   A  YLQ +Y    P  +++  + LDDAGDGS +S  +A ++   R
Sbjct  130  LGRKPVLADYLPVGAAPYYLQYHYIVANPHPAERRKL-LDDAGDGSEYSRLHAMYHPMMR  188

Query  207  EIVTRFDYDDAVLLDTR-GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDF  265
                   + D ++ D + G ++YT+ K+ D  T++  GPYR SN   A  +   +     
Sbjct  189  AAAATLGFFDFMIADPKSGRLIYTVEKEVDFTTSLQAGPYRHSNAAAAAARCAASPDRSA  248

Query  266  TWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGS  325
              + DF PY P  G P A++ APV   G   GVL   L  ++I+ ++T  R+W+  G G 
Sbjct  249  VCLEDFAPYAPSGGAPIAFMGAPVIDRGVVIGVLIAQLSNEEIDNVVTGGRRWRQEGFGD  308

Query  326  GTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEG  385
              E YL GPD L+RS  R F ++ E Y  ++ + G   + +    ++G     Q + T+ 
Sbjct  309  TGEAYLVGPDYLVRSGPRAFYENRENYFAELKSVGAPGEEIAAIERYGTPVQHQRINTKA  368

Query  386  LRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRAL  445
             +AA  G  GT     Y G   L ++ PL +P   + W ++A  + +EAFA +    + L
Sbjct  369  TQAALAGVEGTGEIVGYRGVPTLASWGPLAIPG--IKWGLVAKIDSAEAFAPIERLRQDL  426

Query  446  VLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAF  505
            ++V    ++V+      ++ A++ P+R L  G ++ +AGDY  ++PV++ DEIG L +AF
Sbjct  427  LVVGGLALLVVAATGAWLSRALLGPLRELTAGVRRFAAGDYRASVPVRTHDEIGQLCSAF  486

Query  506  NEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILG  565
            N M  +L  K  ++  + +EN++LLL+++P P+  R R GE+ IA    +VTV FAD++G
Sbjct  487  NGMVEDLHQKNVVIENKNRENEQLLLNVLPAPIANRLRGGEEAIADGFAEVTVAFADLVG  546

Query  566  VDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRT  625
              E++S +  +++V +++EL  +FDSAA  LG+E+I+T+ + Y+A CG+  P  ++  R 
Sbjct  547  FTELTSEMPPHDVVTLLNELFTRFDSAAHDLGIEKIKTVGDAYMAVCGLPEPVANHAERM  606

Query  626  VDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHS  685
            V  A+ M  I      +    + LRVGINTG V++G++G S  +YD+WG  V+LA +M S
Sbjct  607  VRMAIRMVHITREHGMEHNASMKLRVGINTGPVVAGVIGTSKYIYDLWGDTVNLASRMES  666

Query  686  GSPQPGIYVTSQVYEAMRDVWQFTAAGTISVGG  718
            G     I VT  VYE ++  + F   G I V G
Sbjct  667  GGIPDSIQVTRSVYEKLKGQFAFEPRGAIEVKG  699


>gi|333814333|gb|AEG07001.1| adenylate/guanylate cyclase with integral membrane sensor [Sinorhizobium 
meliloti BL225C]
Length=698

 Score =  392 bits (1006),  Expect = 2e-106, Method: Compositional matrix adjust.
 Identities = 226/690 (33%), Positives = 367/690 (54%), Gaps = 6/690 (0%)

Query  32   FRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFS  91
             R  +  KL  +L+L   ++V     + Y   R +L  A +++LT  R+++ R VE  F 
Sbjct  1    MRWGLAVKLFTILVLLGAIAVLVTGVLGYFRARDALEKAVFDQLTAARQTKTRQVEDYFR  60

Query  92   DLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGD  151
             +   L +       VDA   F    DQL  A   P  +Q +  +Y   FI  + R  G 
Sbjct  61   TIDAELRLLASSKMAVDATREFRIVVDQLDRAGAPPELRQKVGTWYTENFIPGITRVLGR  120

Query  152  KLDITALLPTSPAQRYLQAYYTA--PFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIV  209
            K  +   LP   A  YLQ +Y    P  +++  + LDDAGDGS +S  +A ++   R   
Sbjct  121  KPVLADYLPVGAAPYYLQYHYIVANPHPAERRKL-LDDAGDGSEYSRLHAMYHPMMRAAA  179

Query  210  TRFDYDDAVLLDTR-GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWI  268
                + D ++ D + G ++YT+ K+ D  T++  GPYR SN   A  +   +       +
Sbjct  180  ATLGFFDFMIADPKSGRLIYTVEKEVDFTTSLQAGPYRHSNAAAAAARCAASPDRSAVCL  239

Query  269  TDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTE  328
             DF PY P  G P A++ APV   G   GVL   L  ++I+ ++T  R+W+  G G   E
Sbjct  240  EDFAPYAPSGGAPIAFMGAPVIDRGVVIGVLIAQLSNEEIDNVVTGGRRWRQEGFGDTGE  299

Query  329  TYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRA  388
             YL GPD L+RS  R F ++ E Y  ++ + G   + +    ++G     Q + T+  +A
Sbjct  300  AYLVGPDYLVRSGPRAFYENRENYFAELKSVGAPGEEIAAIERYGTPVQHQRINTKATQA  359

Query  389  AQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLV  448
            A  G  GT     Y G   L ++ PL +P   + W ++A  + +EAFA +    + L++V
Sbjct  360  ALAGVEGTGEIVGYRGVPTLASWGPLAIPG--IKWGLVAKIDSAEAFAPIERLRQDLLVV  417

Query  449  TVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEM  508
                ++V+      ++ A++ P+R L  G ++ +AGDY  ++PV++ DEIG L +AFN M
Sbjct  418  GGLALLVVAATGAWLSRALLGPLRELTAGVRRFAAGDYRASVPVRTHDEIGQLCSAFNGM  477

Query  509  SRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDE  568
              +L  K  ++  + +EN++LLL+++P P+  R R GE+ IA    +VTV FAD++G  E
Sbjct  478  VEDLHQKNVVIENKNRENEQLLLNVLPAPIANRLRGGEEAIADGFAEVTVAFADLVGFTE  537

Query  569  ISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDF  628
            ++S +  +++V +++EL  +FD+AA  LG+E+I+T+ + Y+A CG+  P  ++  R V  
Sbjct  538  LTSEMPPHDVVTLLNELFTRFDAAAHDLGIEKIKTVGDAYMAVCGLPEPVANHAERMVRM  597

Query  629  ALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSP  688
            A+ M  I      +    + LRVGINTG V++G++G S  +YD+WG  V+LA +M SG  
Sbjct  598  AIRMVHITREHGMEHNASMKLRVGINTGPVVAGVIGTSKYIYDLWGDTVNLASRMESGGI  657

Query  689  QPGIYVTSQVYEAMRDVWQFTAAGTISVGG  718
               I VT  VYE ++  + F   G I V G
Sbjct  658  PDSIQVTRSVYEKLKGQFAFEPRGAIEVKG  687


>gi|300864236|ref|ZP_07109119.1| putative Adenylate/guanylate cyclase with integral membrane sensor 
[Oscillatoria sp. PCC 6506]
 gi|300337773|emb|CBN54265.1| putative Adenylate/guanylate cyclase with integral membrane sensor 
[Oscillatoria sp. PCC 6506]
Length=728

 Score =  378 bits (971),  Expect = 2e-102, Method: Compositional matrix adjust.
 Identities = 213/686 (32%), Positives = 371/686 (55%), Gaps = 7/686 (1%)

Query  36   IQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTN  95
            I+SKL + LL+ ++ S A +  + +   ++ L    + +LT +R ++   +E+ F  + N
Sbjct  9    IKSKLTIALLVVTLGSTAIVGILTWNRAKSILTQRIFSQLTSVRAAKAAQIESYFQYIHN  68

Query  96   SLVIYERGLTVVDAVVRFTAGFDQL--ADATISPAQQQAIVNYYNNEFITPVERTTGDKL  153
             +        +V A+V F   F QL  +  TISP   Q+I +YY  EF   + +      
Sbjct  69   QIETLSEDRMIVTAMVDFNQAFQQLNQSKLTISPTWNQSIQSYYTKEFFPRLSKNIEGTP  128

Query  154  DITALLPTSPAQRYLQAYY-TAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTRF  212
                  P +   +YLQ +Y T  F        L  A DGS +SA +++++   R ++ +F
Sbjct  129  VFELYAPKTELAQYLQYHYITNNFHPVGKKDELMAATDGSEYSAIHSKYHKILRNLIKKF  188

Query  213  DYDDAVLLDTRGN-IVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDF  271
             Y D  L++     IVY++ K+ D  +N+ TGPY +SNL                 I DF
Sbjct  189  GYYDLFLINPETEEIVYSVYKETDFTSNLQTGPYSQSNLASVVAAVKQNPDPSAVQIVDF  248

Query  272  KPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYL  331
              Y+P  G P A++  P+    +  G+LA+ LP+D+IN I+T +R W+  G+G   ETYL
Sbjct  249  ASYRPSYGAPAAFMAVPIYQETQLVGILAVQLPVDEINSILTGNRGWEREGLGKTGETYL  308

Query  332  AGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQR  391
             G D LMRS SR  ++DP  Y + + + GT   ++    Q   + LLQ V TEG + A +
Sbjct  309  VGSDYLMRSISRFLIEDPINYYQALRSGGTPERIIQTIEQLKTSILLQRVETEGSKKALQ  368

Query  392  GQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTVG  451
            G+ GT    DY     L +YAPL +    ++W +L+  + +EA+  + +    ++++ V 
Sbjct  369  GKQGTEIINDYRQVPVLSSYAPLKI--KGINWVVLSEIDLAEAYEPLNNLQNYIIILAVV  426

Query  452  IIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYE-VNIPVKSRDEIGDLTAAFNEMSR  510
            +++ + + S++ A+  V+PI  L   +++I  G  E   +   ++DE+  L   FNEM R
Sbjct  427  LVLFVTLISLVAANNFVKPIEILIQDSRQIMRGKLEDAELQSTTQDELSHLVKTFNEMIR  486

Query  511  NLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEIS  570
            +LQ +  L  ++++EN+ LLL+++P  V +R++ GE+ I  E +  T+L A + G++E+S
Sbjct  487  SLQDQTILAEQRQRENEELLLNILPSTVAQRWKTGEEGITDETEQATILVASLEGINELS  546

Query  571  SGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFAL  630
             G   +E+  +++E++  FD+AA+ L V  I  +   Y A CG+ TPRLD+  R V+  L
Sbjct  547  IGRGVSEVASLLNEMINGFDAAAQQLDVLGITRIGELYFAVCGLATPRLDHTKRVVELGL  606

Query  631  EMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQP  690
            EM  I+  FN +   +L LR+GI+ G ++  ++   S  Y +WG  +++A Q++  +   
Sbjct  607  EMLDILQAFNNKYNLNLKLRIGIDAGKIMGAVIEAKSFSYYIWGEGLAIASQLNRMAAPN  666

Query  691  GIYVTSQVYEAMRDVWQFTAAGTISV  716
             I + ++V+E +RD++ F  A  I +
Sbjct  667  TIRIPNEVHERVRDLYIFQPAEEIEL  692


>gi|300866763|ref|ZP_07111445.1| putative Globin domain protein [Oscillatoria sp. PCC 6506]
 gi|300335269|emb|CBN56605.1| putative Globin domain protein [Oscillatoria sp. PCC 6506]
Length=866

 Score =  377 bits (968),  Expect = 4e-102, Method: Compositional matrix adjust.
 Identities = 222/692 (33%), Positives = 375/692 (55%), Gaps = 5/692 (0%)

Query  33   RASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSD  92
            R +IQSKL  LLL  S+ SV  ++ I +   + +LR+   E+L  +  ++    E+ F +
Sbjct  23   RWTIQSKLQALLLGVSLGSVVVVSGIGWYQTQATLRSKIAEQLEGISTTKAEQFESYFEN  82

Query  93   LTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERT-TGD  151
            L N + +      VV A+V   +G+  L    I P   +A+  YY+ +F   +++  + +
Sbjct  83   LNNQVGMLAADGNVVKAMVELNSGYRILESNLIPPEWDKALDTYYSEKFFPRLQKNLSPE  142

Query  152  KLDITALLPTSPAQRYLQAYYTAPFTSD-QDAMRLDDAGDGSAWSAANAQFNSYFREIVT  210
             ++ +  +PT  A RYLQ +Y A   +   +  +L DAGDGS +S A+A++  +  EI+ 
Sbjct  143  AINPSVYIPTGQAARYLQYHYIASNPNPVGEKNKLLDAGDGSDYSKAHAKYQQFLAEIIE  202

Query  211  RFDYDDAVLLDTR-GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWIT  269
            RF Y D  L++ + G+I+Y+  K+ D  T+ L G Y +S+L D   K           + 
Sbjct  203  RFGYYDLFLINHKTGDIIYSYFKETDFATSRLQGFYYQSSLADLVQKVQSNPTKGNIQVA  262

Query  270  DFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTET  329
            DFKPY+P    P A++  P+ +G    G+LA+ +P DKI++ ++ +  W+ +G+    E 
Sbjct  263  DFKPYRPSYNAPAAFVATPIYSGSNMIGILAVQIPTDKIDQAISRNNNWETSGLQKTGEA  322

Query  330  YLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAA  389
            YL GPD+LMRS SR +++DP++Y+  V   GT    +     F  T  LQ + +   +AA
Sbjct  323  YLVGPDALMRSTSRFWVEDPKKYQNIVGNTGTDKRTLELMENFKTTIGLQKIDSTAAQAA  382

Query  390  QRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVT  449
              G+ G + +++Y G   L AY+PL +  + L+W+ILA     EA++ + +    L++  
Sbjct  383  LEGKQGMMVNSNYRGVEVLSAYSPLKL--NGLNWAILAEIEVGEAYSPLYNLQIILLIAA  440

Query  450  VGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMS  509
               ++     + + A     P+RRL    +K+SAGD +V + VKS+DE G+L   F E++
Sbjct  441  ALFLLGTAFLAAMAAKIFTTPLRRLSENARKLSAGDLDVEVEVKSQDEFGELATEFKEVA  500

Query  510  RNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVDEI  569
              L+  EE L  + +EN  LL +++P  + ER + GE++IA   + VT+L  ++ G+ E+
Sbjct  501  NKLRQTEEQLQIKDRENSILLNNILPNAIAERRKQGEESIADNLKQVTILNVNLAGISEL  560

Query  570  SSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVDFA  629
            +  LS  ++ +++ +L   FDSAAE  G+ER+ +    Y+A CG+T  R D+  R VD A
Sbjct  561  NKRLSPQKMTELLTQLFDDFDSAAERYGLERLNSATTSYMAVCGLTQARFDHSQRAVDLA  620

Query  630  LEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGSPQ  689
            L M  I+ R N    + L LR+ I+ G V +G+VG     Y +WG    +A  + +    
Sbjct  621  LVMLEIIQRLNVNYNSPLALRISIHAGSVTTGVVGTERFGYKIWGETAYIASSLQNQPNL  680

Query  690  PGIYVTSQVYEAMRDVWQFTAAGTISVGGLEE  721
              I +T  VYE + D + F     + + G  E
Sbjct  681  NYILLTQSVYERIADSYTFIKNPVVKIQGFPE  712


>gi|220906967|ref|YP_002482278.1| adenylate/guanylate cyclase with integral membrane sensor [Cyanothece 
sp. PCC 7425]
 gi|219863578|gb|ACL43917.1| adenylate/guanylate cyclase with integral membrane sensor [Cyanothece 
sp. PCC 7425]
Length=758

 Score =  357 bits (916),  Expect = 5e-96, Method: Compositional matrix adjust.
 Identities = 215/688 (32%), Positives = 366/688 (54%), Gaps = 20/688 (2%)

Query  35   SIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLT  94
            SI+SKL ++LL+ S+ S+  +A +     +  L    + +LT +R ++   +ET F  L 
Sbjct  26   SIKSKLQIMLLIVSLGSIVVVAYLSLSKAQQILTQRIFAQLTSVRTAKADQIETYFHTLR  85

Query  95   NSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDKLD  154
            + L        V  A+  F   + +L D  I P   +AI +YYN EF+  + +       
Sbjct  86   HQLETLSESRMVATAMQDFNRDYQKLNDQKIPPVWDRAIESYYNQEFLPRLSKHIDGTPI  145

Query  155  ITALLPTSPAQRYLQAYYTA----PFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVT  210
                 PTSP  R+LQ  Y A    P     D ++     DGS +S  +A ++ +FR +V 
Sbjct  146  FATYRPTSPESRFLQYQYIAHNPNPVGEKDDLLQ---PKDGSNYSKVHALYHPFFRNLVQ  202

Query  211  RFDYDDAVLLDTR-GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWIT  269
            R  Y+D  L+D   G+++Y++ K+ D  +N+ TGPYR+SNL     +           + 
Sbjct  203  RLGYEDLFLIDAETGDVIYSVKKETDFASNLYTGPYRDSNLAAVVKEVRNNPDRGAIQLV  262

Query  270  DFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTET  329
            DF+ Y+P    P A++ A +  G +  G+L + L  D IN+I+T ++QW+  G+G   ET
Sbjct  263  DFQFYRPSYNAPAAFMAASIFDGTRRVGILVVQLSSDTINQILTGNQQWKQQGLGETGET  322

Query  330  YLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAA  389
            Y+ G D  +RS  RL ++ P  Y   +   G S + +    +   + LLQP+ T   +AA
Sbjct  323  YIVGDDFRLRSVLRLLIEQPSAYFNALRREGVSPETIQSIQRLNSSLLLQPIETVAAQAA  382

Query  390  QRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVT  449
             +G+TGT     Y GS  L +YAPLN+    ++W I++    SEAFA + +  + L+L  
Sbjct  383  LQGKTGTQILPGYRGSLVLASYAPLNI--RGVNWGIISEMALSEAFAPINALQQYLLLSA  440

Query  450  VGIIVVICVASMLIAHAMVRPI-----RRLEVGTQKISAGDYEVN----IPVKSRDEIGD  500
            + +I+++ + + + A   VRPI     R    G   +  G+ +V+    +   S+DE+ +
Sbjct  441  IIMILLVTLFAAIAAQRFVRPIDLMVQRYGNCGADPLPDGE-DVSSLSELKFGSQDELSE  499

Query  501  LTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLF  560
            L    N M   +  K   + E+ KEN+ LLL+++P PV+ER+R GE+ I  + Q VTV+ 
Sbjct  500  LAQICNGMVVQIHQKTAAIAEKEKENETLLLNILPRPVMERWRKGEKQIIDQVQQVTVIV  559

Query  561  ADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLD  620
              I+G++   +      + + ++EL+   D  A+   VER+    + Y+A CG+T PRLD
Sbjct  560  VQIVGLERAMTQPDNQMMAEGLNELITLLDKKADKFDVERLNCFGDRYVAVCGLTKPRLD  619

Query  621  NIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLA  680
            ++ R VDFA +  +++   N +   +L+LR+GI+TG V + L+G+  V YD+WG  VS+A
Sbjct  620  HVKRGVDFAQDGLQLIKEVNQKYSLNLNLRMGIHTGAVTAALIGQKKVCYDIWGETVSIA  679

Query  681  YQMHSGSPQPGIYVTSQVYEAMRDVWQF  708
             Q+   +    +  T+ + +++ D++ F
Sbjct  680  TQLAQQAETDTLRATANICDSVPDLFPF  707


>gi|254425852|ref|ZP_05039569.1| Globin domain protein [Synechococcus sp. PCC 7335]
 gi|196188275|gb|EDX83240.1| Globin domain protein [Synechococcus sp. PCC 7335]
Length=876

 Score =  343 bits (879),  Expect = 8e-92, Method: Compositional matrix adjust.
 Identities = 210/689 (31%), Positives = 359/689 (53%), Gaps = 11/689 (1%)

Query  35   SIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLT  94
            + +SKL++L L  SI SV  IA +     R  LR AA+ +L  LR  Q   V+  F  L 
Sbjct  12   TFKSKLILLTLFASISSVIVIAILSIGLSRRGLRQAAFSQLNVLRSEQAEQVQNYFQQLQ  71

Query  95   NSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDKLD  154
            +  +       +V A+V F   F +L    I     + +  YY   +   +   TG +  
Sbjct  72   SHTLTLSANRAIVVAMVEFNKEFRRLDRQFIPTEWDEPLKRYYEANYFPRLSDITGSEPR  131

Query  155  ITALLPTSPAQRYLQAYYTAPFTS-DQDAMRLDDAGDGSAWSAANAQFNSYFREIVTRFD  213
              +  P+  A RYLQ YY +     D +  +L  A D S +S  +++F+    +I  +F 
Sbjct  132  FGSYRPSGQAARYLQHYYLSQNDYLDAEKNQLITADDDSEYSRYHSEFHPLLNDIAQQFG  191

Query  214  YDDAVLLDTR-GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFK  272
            Y D  L++ + G+IVY+++K PD GTN+ TG YR+S+L D       ++A     I DF 
Sbjct  192  YADLYLINQKTGDIVYSVNKRPDYGTNLETGAYRDSSLADLVATVRESSARGEVAIADFA  251

Query  273  PYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLA  332
            PY+P  GVP+ ++ +P+  G    G+LA+ L  D+I+++MT           +  ++YL 
Sbjct  252  PYEPASGVPSLFIASPIYNGPYVVGILAIRLETDQISQLMTETLTEDTPS--TSLDSYLV  309

Query  333  GPDSLMRSDSRLF-----LQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLR  387
            G D  +RS+ + F       D + Y +++   G S + +    +     LLQPV     +
Sbjct  310  GADGSLRSEPQFFRDSLSKDDIQSYTRRLRRQGVSDETLAAITRLESPVLLQPVKAAAAQ  369

Query  388  AAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVL  447
            +A  G T T    DY G   L AYAPL +    L W++++  + +EAFA +     A+++
Sbjct  370  SAIGGATDTERLQDYRGVSVLSAYAPLEI--EGLDWAVISQIDTAEAFATLTHLELAILV  427

Query  448  VTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNE  507
             ++ +I      +M  A   ++P+R+L     ++  GD+E  I +   DEIG LT     
Sbjct  428  ASILLITAFTFLAMAAATMTIQPVRQLNEWADRVVDGDFEAEIDLDLEDEIGQLTDTLQI  487

Query  508  MSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLFADILGVD  567
            M  +L  +   L+++  +N+ LL +++P  + +R + GE  IA + + +TV++A+I+G+ 
Sbjct  488  MVTSLSHQVATLDQKMAQNEVLLTNLVPPAIAKRLKRGETIIADQIRQITVIYANIVGIS  547

Query  568  EISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLDNIPRTVD  627
            E+S  LS  E+  ++ +L++ FD   E  G+ER  T    Y+A CG+TT RLD+  RTVD
Sbjct  548  ELSQTLSPEEVTALLTKLMQAFDDVGEQHGMERQNTPSVDYMAICGLTTARLDHTKRTVD  607

Query  628  FALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLAYQMHSGS  687
            FALEM +I++         L LR+ ++TG V +G+VG     Y +WG ++ L  ++++ +
Sbjct  608  FALEMLKIINLPEFGQSFALGLRLAVHTGPVTAGVVGTKRFGYSVWGESIYLVTRLYAHA  667

Query  688  PQPGIYVTSQVYEAMRDVWQFTAAGTISV  716
                + +T   Y+ + + +   AAG +++
Sbjct  668  ALNSVVLTEAAYQQIAETYTCVAAGAVAI  696


>gi|158425589|ref|YP_001526881.1| adenylate cyclase [Azorhizobium caulinodans ORS 571]
 gi|158332478|dbj|BAF89963.1| putative adenylate cyclase [Azorhizobium caulinodans ORS 571]
Length=739

 Score =  332 bits (852),  Expect = 1e-88, Method: Compositional matrix adjust.
 Identities = 215/682 (32%), Positives = 356/682 (53%), Gaps = 22/682 (3%)

Query  35   SIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLT  94
            SI+SK++ +LL+  I  + A + +  +SG T+L+++ +++LT LR ++   V   F D++
Sbjct  30   SIRSKVLAMLLICGIGCLVAASLVAMRSGTTTLKSSIFDQLTTLRTAKAAQVVNWFQDVS  89

Query  95   NSLVIYERGLTVVDAVVRFTAGFDQL---ADATISPAQQQAIVNYYNNEFITPVERTTGD  151
            +      +  + +  +  F+A + +    A AT +P     +  YY ++F+         
Sbjct  90   DDFSDISQDASTIAGIQAFSAAYLRAGVGASATPTPE----LDAYYKDKFLPSFAMLVDA  145

Query  152  KLDITALLPTSPAQRYLQAYYTA----PF----TSDQDAMRLDDAGDGSAWSAANAQFNS  203
             L     LP SPA   LQA Y      P      S +D  +  D+G  +A+  A A+F  
Sbjct  146  PLVPRGFLPASPAALRLQAAYVTRNANPVGTEGVSREDTGQPADSGL-AAYDDAVARFQP  204

Query  204  YFREIVTRFDYDDAVLLDTR-GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKAL-GAN  261
            +FR  V     +D +L+DTR G IVYT++K  DLG ++ +G    S    A+ + + G  
Sbjct  205  FFRRAVETHALEDILLVDTRSGTIVYTVAKRTDLGASLKSGSLSTSGAARAFSRVIEGGG  264

Query  262  AVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAA  321
                T + DF  Y P    P+A++ APV + G   GV+   L + +IN +MT DR W+ A
Sbjct  265  VPGHTVLEDFSAYIPAGLRPSAFIAAPVFSDGNLVGVVIGVLSVKQINALMTNDRHWEEA  324

Query  322  GMGSGTETYLAGPDSL-MRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQP  380
            G+G   E YL G + L MRS SR  +QDP  Y K + A G S + + R   F    + Q 
Sbjct  325  GLGRTGEVYLVGVNELLMRSPSRFLIQDPAAYFKALEATGVSSETLARIRHFDSPIMAQK  384

Query  381  VATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVAS  440
            V+TE  R  Q+G++ T    DY G   L ++ P+ V    LHW ++A ++++EA A V  
Sbjct  385  VSTEATREGQKGRSDTQIVADYRGVSTLSSWGPVAV--QGLHWIVVAQQDEAEALAPVDG  442

Query  441  FSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGD  500
               ++++V     V++   S+ +A    RPI+ +  G   ++AGD  V IPVK RDE  D
Sbjct  443  LRHSILVVAALAAVILTAISVALASVFTRPIQAVLAGVNTLAAGDESVRIPVKGRDEFAD  502

Query  501  LTAAFNEMSRNLQTKEELLNEQRKENDRLLLSMMPEPVVERYRLGEQTIAQEHQDVTVLF  560
            L  AFN M+  +  +   + ++  E ++LL +  P+ + +R R GE   ++  ++V V+ 
Sbjct  503  LARAFNAMANEIAERSARIEQKTVEYEQLLRNFYPDLIADRIRNGEGAFSEHVRNVCVVV  562

Query  561  ADILGVDEISSGLSGNELVKIVDELVRQFDSAAEHLGVERIRTLHNGYLAGCGVTTPRLD  620
              I G + +  G SG  L + V+ +V   D      G+E+IRT+   Y+A CG++TPRLD
Sbjct  563  LIIEGFEGLVRGGSGETLER-VNAVVGDLDELCTAGGLEKIRTIGETYMAACGLSTPRLD  621

Query  621  NIPRTVDFALEMRRIVDRFNCQTGNDLHLRVGINTGDVISGLVGRSSVVYDMWGAAVSLA  680
               R + F  ++   +DR +     +L +R G+  GDV  G+VGR  ++YD+WGA +  A
Sbjct  622  AAQRGLAFVEQVSGALDRLSRVYEVELSVRAGVALGDVEVGIVGRHRMLYDVWGATMLEA  681

Query  681  YQMHSGSPQPGIYVTSQVYEAM  702
             ++   +    + VT  V++ +
Sbjct  682  RRIVFDAEPGTVRVTEAVFQQL  703


>gi|262275612|ref|ZP_06053421.1| methyl-accepting chemotaxis protein [Grimontia hollisae CIP 101886]
 gi|262219420|gb|EEY70736.1| methyl-accepting chemotaxis protein [Grimontia hollisae CIP 101886]
Length=771

 Score =  244 bits (624),  Expect = 3e-62, Method: Compositional matrix adjust.
 Identities = 154/489 (32%), Positives = 250/489 (52%), Gaps = 21/489 (4%)

Query  35   SIQSKLMVLLLLTSIVSVAAIAAIV----YQSGRTSLRAAAYERLTQLRESQKRAVETLF  90
            +I SK+ +  +  S  +V A A ++      +  T++      +L  +RE +K  VE  F
Sbjct  2    NISSKIKMAFVAISATAVIATAGLLATTAIDASTTAMEKQIENQLLSVREVKKSEVENYF  61

Query  91   SDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIV-NYYNNEFITPVERTT  149
            ++++  L+         DA+V+F+  F+ +A  T   + Q AI+ +YY N F    + T 
Sbjct  62   TNISKQLINLANSTMTEDAMVQFSQSFNSVATETFPKSNQAAILKDYYQNAFAAVYQETN  121

Query  150  GDKLD-ITALLPTSPAQRYLQAYYTA----PFTSDQDAMRLDDAGDGSAWSAANAQFNSY  204
             +  + +T L         LQ  Y      P  S      LD A DG+ +S  +  F++ 
Sbjct  122  NEPTNALTHLNDIDLNGLLLQQAYIGLNKNPLGSKH---LLDKANDGTIYSEVHEVFHNN  178

Query  205  FREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVD  264
            +R  +  F Y D  L+D  GN+VY++ K+ D  TN+ TGPY+ S L +A++ A   N  D
Sbjct  179  YRTFLESFGYYDIFLIDNAGNVVYSVFKELDYATNLQTGPYKNSGLAEAFISAKDLNKGD  238

Query  265  FTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMG  324
            F ++ DFKPY P    P +++  PV  GG+  GVLA  +PID IN IMT++ +W+  GMG
Sbjct  239  FAFV-DFKPYYPSYDSPASFIGTPVIKGGRHVGVLAFQMPIDTINSIMTSNGKWRENGMG  297

Query  325  SGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATE  384
               E +L G D LMRS +R+ + + +EY K +   G S +V+ R      +T  QPV ++
Sbjct  298  ESGELFLVGSDGLMRSQARMLVDNKDEYLKHLGETGVSPNVIERISTTNSSTGQQPVNSK  357

Query  385  GLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAV----AS  440
                A  G+ G VTS ++ GS    AY P+ + D+   W ++A  +  EA A V    ++
Sbjct  358  HADQALDGKKGFVTSENHLGSTVFAAYTPIKILDT--QWGLIAEISKQEALANVHALQST  415

Query  441  FSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISA-GDYEVNIPVKSRDEIG  499
              +A  +  + II +  + + L+A ++ RPI  L      I+   D  V +  K +DEI 
Sbjct  416  LHQAAGITGIVIIAIAMICAWLMASSISRPIVALTHHITTIATHHDLTVRLNTKGKDEIA  475

Query  500  DLTAAFNEM  508
             L+++ N M
Sbjct  476  QLSSSMNAM  484


>gi|83815947|ref|YP_446697.1| methyl-accepting chemotaxis protein [Salinibacter ruber DSM 13855]
 gi|83757341|gb|ABC45454.1| methyl-accepting chemotaxis protein [Salinibacter ruber DSM 13855]
Length=932

 Score =  240 bits (612),  Expect = 7e-61, Method: Compositional matrix adjust.
 Identities = 155/494 (32%), Positives = 259/494 (53%), Gaps = 12/494 (2%)

Query  23   KNVLRRRPRFRA-SIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRES  81
            ++V    PR R  SI++KL++ LL    +SV  +  I Y S R  L + A  RL  ++ +
Sbjct  22   QHVFSVMPRLRDLSIRAKLLLTLLGIGGLSVGIMGWIGYSSARQRLESEALGRLAGVQAN  81

Query  82   QKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISP--AQQQAIVNYYNN  139
            +  AVE    DL   +V   +    V A+ +F + F  L     +P      A+  YY +
Sbjct  82   KANAVEAYVEDLRRQVVTTSKDDQTVRAMQKFRSAFRVLDARNAAPIGGGTAAVRTYYED  141

Query  140  EFITPVERTTGDKLDITALLPTSPAQRYLQAYYTA--PF-TSDQDAMRLDDAGDG-SAWS  195
            EF   +E  TG      + +P     +YLQ  Y A  P    ++D  RLD  G+G   + 
Sbjct  142  EFGPRLEEGTGTDGAAASYVPEEGHIQYLQNKYIASNPHPVGEKD--RLDRPGEGWEVYH  199

Query  196  AANAQFNSYFREIVTRFDYDDAVLLD-TRGNIVYTLSKDPDLGTNILTGPYRESNLRDAY  254
              +A+++  FR ++  F++ D  L++   G++VY++ K+ D GT++L GPYR+SNL +A+
Sbjct  200  VPHARYHDAFRRLLHAFNHADLFLVEPDNGHVVYSVQKEVDFGTSLLDGPYRDSNLAEAF  259

Query  255  LKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTA  314
              A GA   D   + DF  Y P  G P +++ +P+   G+  GVL   + + +IN+ +T 
Sbjct  260  RAARGAETGDAHRMVDFAAYGPSHGTPASFVASPIMDAGEVIGVLVFQVSVGEINETLTG  319

Query  315  DRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGG  374
             + W A G+G   ET L G D  MR+D+R  L+D + Y + + + G     ++R      
Sbjct  320  GQDWAAEGLGETGETVLVGADRRMRTDARFLLEDQDAYLQTLRSQGHDDATIDRIDALNT  379

Query  375  TTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEA  434
            T L Q V  E +  A  G TG  T  DY G   L AY P+++    ++W++++  +  EA
Sbjct  380  TILQQEVRMEAVDRALAGSTGRTTEADYRGEAVLSAYGPVDL--EGVNWAVVSKIDRDEA  437

Query  435  FAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKS  494
             AAV + +  + L    ++V++   + ++  ++ RP+  L    +K +AG  +  +PV+ 
Sbjct  438  LAAVDALTGRIALWGGALLVLVAGIAFVVVRSLTRPLLALRDAARKATAGTLDAAVPVEG  497

Query  495  RDEIGDLTAAFNEM  508
            +DE+G+LTAAFNEM
Sbjct  498  QDEVGELTAAFNEM  511


>gi|294508633|ref|YP_003572692.1| methyl-accepting chemotaxis protein DcrH [Salinibacter ruber 
M8]
 gi|294344962|emb|CBH25740.1| Methyl-accepting chemotaxis protein DcrH [Salinibacter ruber 
M8]
Length=932

 Score =  240 bits (612),  Expect = 8e-61, Method: Compositional matrix adjust.
 Identities = 155/494 (32%), Positives = 259/494 (53%), Gaps = 12/494 (2%)

Query  23   KNVLRRRPRFRA-SIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRES  81
            ++V    PR R  SI++KL++ LL    +SV  +  I Y S R  L + A  RL  ++ +
Sbjct  22   QHVFSVMPRLRDLSIRAKLLLTLLGIGGLSVGIMGWIGYSSARQRLESEALGRLAGVQAN  81

Query  82   QKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISP--AQQQAIVNYYNN  139
            +  AVE    DL   +V   +    V A+ +F + F  L     +P      A+  YY +
Sbjct  82   KANAVEAYVEDLRRQVVTTSKDDQTVRAMQKFRSAFRVLDARNAAPIGGGTAAVRTYYED  141

Query  140  EFITPVERTTGDKLDITALLPTSPAQRYLQAYYTA--PF-TSDQDAMRLDDAGDG-SAWS  195
            EF   +E  TG      + +P     +YLQ  Y A  P    ++D  RLD  G+G   + 
Sbjct  142  EFGPRLEEGTGTDGAAASYVPEEGHIQYLQNKYIASNPHPVGEKD--RLDRPGEGWEVYH  199

Query  196  AANAQFNSYFREIVTRFDYDDAVLLD-TRGNIVYTLSKDPDLGTNILTGPYRESNLRDAY  254
              +A+++  FR ++  F++ D  L++   G++VY++ K+ D GT++L GPYR+SNL +A+
Sbjct  200  VPHARYHDAFRRLLHAFNHADLFLVEPDNGHVVYSVQKEVDFGTSLLDGPYRDSNLAEAF  259

Query  255  LKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTA  314
              A GA   D   + DF  Y P  G P +++ +P+   G+  GVL   + + +IN+ +T 
Sbjct  260  RAARGAETGDAHRMVDFAAYGPSHGTPASFVASPIMDAGEVIGVLVFQVSVGEINETLTG  319

Query  315  DRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGG  374
             + W A G+G   ET L G D  MR+D+R  L+D + Y + + + G     ++R      
Sbjct  320  GQDWAAEGLGETGETVLVGADRRMRTDARFLLEDQDAYLQTLRSQGHDDATIDRIDALNT  379

Query  375  TTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEA  434
            T L Q V  E +  A  G TG  T  DY G   L AY P+++    ++W++++  +  EA
Sbjct  380  TILQQEVRMEAVDRALAGSTGRTTEADYRGEAVLSAYGPVDL--EGVNWAVVSKIDRDEA  437

Query  435  FAAVASFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVKS  494
             AAV + +  + L    ++V++   + ++  ++ RP+  L    +K +AG  +  +PV+ 
Sbjct  438  LAAVDALTGRIALWGGALLVLVAGIAFVVVRSLTRPLLALRDAARKATAGTLDAAVPVEG  497

Query  495  RDEIGDLTAAFNEM  508
            +DE+G+LTAAFNEM
Sbjct  498  QDEVGELTAAFNEM  511


>gi|260777498|ref|ZP_05886392.1| methyl-accepting chemotaxis protein [Vibrio coralliilyticus ATCC 
BAA-450]
 gi|260607164|gb|EEX33438.1| methyl-accepting chemotaxis protein [Vibrio coralliilyticus ATCC 
BAA-450]
Length=770

 Score =  221 bits (563),  Expect = 3e-55, Method: Compositional matrix adjust.
 Identities = 151/491 (31%), Positives = 250/491 (51%), Gaps = 27/491 (5%)

Query  42   VLLLLTSIVSVAAIAAIVYQSGRTS------LRAAAYERLTQLRESQKRAVETLFSDLTN  95
            ++L  T + S+A +A   +   R S      L   A  +LT +RE++K  +E  F  +  
Sbjct  7    IVLASTLLCSIAVVATGTFVGWRASELSEQALYQRAISQLTSIRENKKSEIENYFQHIRG  66

Query  96   SLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDKL--  153
             +V     + V DA+V F   F++    ++S +   ++ NYY + F T      G     
Sbjct  67   QIVTTANSIGVRDAMVAFKDTFERYPVESVSSSDLSSLSNYYTSNFGTTYRTANGGNSAN  126

Query  154  DITALLPTSPAQRYLQAYYTA----PFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIV  209
            ++  L   SP  + LQA Y      P   ++  M  D  G  + +   + +++   +  +
Sbjct  127  ELQKLNMLSPRAKALQARYIGVNPNPL-GEKHQMMADSLG--TEYDKVHNKYHPSIKGFL  183

Query  210  TRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWIT  269
              F Y D  L+D  GN+VY++ K+ D  TN+ +GPY  S +  A+  AL   A  +  + 
Sbjct  184  EEFGYYDIFLVDPSGNVVYSVFKELDYATNLNSGPYAGSGIAKAFKNALNKGASQY-HLE  242

Query  270  DFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTET  329
            DF PY P      +++  PV+   KT GVL   +P+DKIN IMT    W  AG+G+  ET
Sbjct  243  DFAPYFPSYEAAASFIATPVKVDNKTIGVLIFQMPVDKINSIMTFGENWSYAGLGNSGET  302

Query  330  YLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTL-LQPVATEGLRA  388
            YL GPDSL+RS+SR  L++PE Y +++ A+G S +++++ IQ   + +  Q V T  ++A
Sbjct  303  YLVGPDSLLRSESRFLLEEPELYFEELKASGVSKNIMDQ-IQGKSSAIGRQMVDTASVKA  361

Query  389  AQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAV-----ASFSR  443
            A RGQ+G+    DY G   L  Y+PL+   + L W+I+   + +EA A +     + F+ 
Sbjct  362  AFRGQSGSEVVDDYRGIEVLSVYSPLDA--AGLQWAIVTEIDKAEALADLDALVQSKFTT  419

Query  444  ALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKISA-GDYEVNIPVKSRDEIGDLT  502
             L  + VG+   + V S  +  ++ +PIR      Q+IS   D    + V+ +DE+ DL 
Sbjct  420  VLTSIVVGVTAAVLV-SYFLGSSISKPIRVASEKIQRISRDNDLTERLDVEGKDEMTDLA  478

Query  503  AAFNEMSRNLQ  513
             + N +  +LQ
Sbjct  479  VSLNSLFTHLQ  489


>gi|124003802|ref|ZP_01688650.1| PAS domain S-box protein [Microscilla marina ATCC 23134]
 gi|123990857|gb|EAY30324.1| PAS domain S-box protein [Microscilla marina ATCC 23134]
Length=1528

 Score =  221 bits (563),  Expect = 3e-55, Method: Compositional matrix adjust.
 Identities = 128/482 (27%), Positives = 240/482 (50%), Gaps = 13/482 (2%)

Query  45   LLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGL  104
            +L  IV +  +  + +      LR   +++L  +RE +K+ +E  F  + N +    +  
Sbjct  1    MLVGIVPLIILMFLGFWFTGNLLRKKNFDQLNAIREYKKQTIEEYFQLVRNEIQYLSKNH  60

Query  105  TVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITALLPTSPA  164
            T+V+A+  F   F   A   ++      + +YY ++    +     +  ++  L+P    
Sbjct  61   TIVNAMREFKDSFHASAPTRLNENDIAKVKSYYKDKIFKKLGNNLSN-FELNRLIPQDST  119

Query  165  QRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTR-  223
              + Q YY A               +   +   + ++N      + +F Y D +L+D   
Sbjct  120  TLFFQRYYMAEMAG---------IKNDHPYHDVHTKYNQDITNFLKKFKYYDILLIDNET  170

Query  224  GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTA  283
            G+I+Y++ K+ D  T++ TGPY +SN+   + +   A   DF  I DF+ Y P    P  
Sbjct  171  GHIIYSVDKEIDFATSLKTGPYSQSNIAKVFQEVKQAREPDFVKIYDFEQYTPSFMFPAM  230

Query  284  WLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSR  343
            ++  PV  G +  G L   L   +I++ MT + +W   G+G   E+Y+ G DS MR+D+R
Sbjct  231  FIGTPVFDGKRNIGTLVFELSTKEIDRTMTNEHKWTEVGLGKTGESYIVGRDSKMRNDAR  290

Query  344  LFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYT  403
              ++DP+ + K +     +   + +  QF  + L Q + TE ++ A  G+     +TDY 
Sbjct  291  AMIEDPKAFLKLLTKLKLNAGDLEKMKQFQSSILFQEIKTEAVKDAYLGRVDAKIATDYR  350

Query  404  GSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICVASMLI  463
              R L +Y PL +P  DL W ++   ++ E    + SF+R      + ++++I V ++L+
Sbjct  351  NQRVLTSYTPLKIP--DLEWFLVTQIDEKEVMQPMDSFARKAYQGVLILLIIILVITLLL  408

Query  464  AHAMVRPIRRLEVGTQKISAGDYEVNIPVKSRDEIGDLTAAFNEMSRNLQTKEELLNEQR  523
            +  +  PI++L  GT+ I  G  +  + V S+DEIGDL  +FN+M++N++ K E L+E+R
Sbjct  409  SKNLSSPIKQLLEGTKNIQQGKLDTEVQVTSKDEIGDLAHSFNQMAQNIKEKNESLDEKR  468

Query  524  KE  525
            ++
Sbjct  469  QK  470


>gi|331006729|ref|ZP_08330002.1| methyl-accepting chemotaxis sensory transducer [gamma proteobacterium 
IMCC1989]
 gi|330419461|gb|EGG93854.1| methyl-accepting chemotaxis sensory transducer [gamma proteobacterium 
IMCC1989]
Length=814

 Score =  212 bits (540),  Expect = 2e-52, Method: Compositional matrix adjust.
 Identities = 149/495 (31%), Positives = 240/495 (49%), Gaps = 33/495 (6%)

Query  36   IQSKLMV----LLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFS  91
            I +K+++    L ++  +VS   +A I     R +L   A + L  +R+     +     
Sbjct  3    INTKMIIGGGFLSVIPVVVSGIFLANIAINESRVALEEDAKQSLIAIRDITATEITNYIH  62

Query  92   DLTNSLVIYERGLTVVDAVVRFTAGFDQLADA---TISPAQQQAIVNYYNNEFITP-VER  147
             +          L VVDA+  F+  F + A     + S  Q+ ++ NYY   F     E 
Sbjct  63   TIEKEAASLSENLMVVDAMNEFSTAFSEYASNIPNSESAQQKNSVDNYYRQAFGQHFAEL  122

Query  148  TTGDKLDITALLPTSPAQRYLQAYYTAPFTSDQDA-----MRLDDAGDGSAWSAANAQFN  202
                ++D TALL +   +     Y    F S+ D+      +LD     S+++  + +++
Sbjct  123  NHNTQIDTTALLGSLDKESIALQY---DFISNNDSPLGSKHQLDKPTRASSYANHHEKYH  179

Query  203  SYFREIVTRFDYDDAVLLDTR-GNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGAN  261
              FR+ + RF + D  L+D R G+IVY++ K+ D  T+++ GPY  S +  A+ KA  A+
Sbjct  180  PVFRKYIERFGFYDLFLVDHRTGDIVYSVFKELDYATSLIDGPYANSGIGQAFRKANNAD  239

Query  262  AVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAA  321
            + DFT +TDF PY P    P +++  P+       G+L L +PID IN +MT ++ W+ +
Sbjct  240  STDFTGLTDFAPYVPSYNAPASFIATPIYDKNLKVGILILQMPIDNINAVMTHNQDWKNS  299

Query  322  GMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPV  381
            G+G   E+YL G D  MRS+ R  L+D   Y   +   G     +        T  LQPV
Sbjct  300  GLGDSGESYLVGADFTMRSNGRFLLEDKVAYLDLMSHIGLPKKTIEELDTKNTTIGLQPV  359

Query  382  ATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASF  441
             TEG  AA  G+ G     DY G   L AY PLN+    L W+I++  +++EAFA V + 
Sbjct  360  QTEGTEAALSGEKGYAIFPDYRGISVLSAYKPLNI--GGLQWAIMSEIDETEAFAPVENI  417

Query  442  SRALVLVTVGIIVVICVAS-----MLIAHAMVRPIRRLEVGTQKISA-----GDYEVNIP  491
              A+   T+ II++I +A+      L+A  +V PI++L   TQ I +     GD    + 
Sbjct  418  KSAITQTTL-IILLIALATGPLLGWLLASTVVGPIKKL---TQTIHSMADGEGDLTQRLD  473

Query  492  VKSRDEIGDLTAAFN  506
             K   E+ +L    N
Sbjct  474  DKGTSELHELAMWLN  488


>gi|323497131|ref|ZP_08102151.1| methyl-accepting chemotaxis protein [Vibrio sinaloensis DSM 21326]
 gi|323317706|gb|EGA70697.1| methyl-accepting chemotaxis protein [Vibrio sinaloensis DSM 21326]
Length=770

 Score =  211 bits (536),  Expect = 5e-52, Method: Compositional matrix adjust.
 Identities = 144/491 (30%), Positives = 242/491 (50%), Gaps = 15/491 (3%)

Query  36   IQSKLMVLLLLTSIVSVAAIAAIV-YQSGRTS---LRAAAYERLTQLRESQKRAVETLFS  91
            I +K++    L   ++V A   IV ++S   S   L   A E+L  +RE +K  +E  F 
Sbjct  3    IATKIVSASTLLCTLAVIATGVIVGWRSAALSEEALYKRATEQLISVREIKKHEIELYFE  62

Query  92   DLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGD  151
             +   L+     + V DA+  F+  F       +  +   A+  YY  +F        G 
Sbjct  63   QIRGQLITTANSVGVQDAISAFSDSFASYPVERVKESDIGALSQYYQTQFGATYRSANGG  122

Query  152  KL--DITALLPTSPAQRYLQAYYTAPFTSD-QDAMRLDDAGDGSAWSAANAQFNSYFREI  208
                ++  L   S   + LQA Y    ++   +  +L     G+ +   +A+++   +  
Sbjct  123  AAANEMQKLAMLSSRAKALQARYIGANSNPLGEKHQLMSDSLGTDYDQVHAKYHPSIKGF  182

Query  209  VTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWI  268
            +  F Y D  L+D +GN+VY++ K+ D  TN+  GPY  S +  AY  A+      F  +
Sbjct  183  LEEFGYYDIFLVDPQGNVVYSVFKELDYATNLKQGPYAGSGIAKAYNSAMSKGQNQF-HL  241

Query  269  TDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTE  328
             DF PY P      +++  P++  G+T GVL   +P+D+IN IMT + +W  AG+G   E
Sbjct  242  EDFAPYYPSYQAAASFIATPIKQDGQTLGVLIFQMPVDEINNIMTFNGKWGHAGLGESGE  301

Query  329  TYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRA  388
            +YL GPD L+RS+SR  ++DPE+Y   +  AG +   + +    G     +PV+T   +A
Sbjct  302  SYLVGPDGLLRSESRFLMEDPEQYFAAMEQAGMASATLAQIRGKGSAIGRKPVSTPTSKA  361

Query  389  AQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLV  448
            A RGQ+G+   TDY G   L AYAP+N   + L W IL   +  EA   V     A+V+ 
Sbjct  362  ALRGQSGSDVVTDYRGVGVLSAYAPVNA--AGLSWGILTEIDKDEALKDVGGLISAMVVT  419

Query  449  TVGIIVVICVASMLIAHAMVRPIRR-LEVGTQKI----SAGDYEVNIPVKSRDEIGDLTA  503
             +  IVVI + ++ I++ + R I + +++ ++KI       D    + V  +DE+ +L  
Sbjct  420  VLTSIVVIVLVAIAISYFLGRSIAQPIKIASEKIQHISKNNDLTQRLEVSGKDEMTELAI  479

Query  504  AFNEMSRNLQT  514
            + N +  +LQ+
Sbjct  480  SLNGLFTHLQS  490


>gi|170724924|ref|YP_001758950.1| methyl-accepting chemotaxis sensory transducer [Shewanella woodyi 
ATCC 51908]
 gi|169810271|gb|ACA84855.1| methyl-accepting chemotaxis sensory transducer [Shewanella woodyi 
ATCC 51908]
Length=773

 Score =  209 bits (532),  Expect = 1e-51, Method: Compositional matrix adjust.
 Identities = 150/482 (32%), Positives = 244/482 (51%), Gaps = 24/482 (4%)

Query  49   IVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVD  108
            I++  ++  I Y+ G+  +   A   LT +R+ +K  +E  +S L   +        ++ 
Sbjct  20   IIACISVGLIAYKMGQEIIHEQAENHLTSIRDIKKDQIERYYSTLKRQVQTLSNDRMIIT  79

Query  109  AVVRFTAGFDQLADATISPAQQQAIVNYYNNEF------ITPVERTTGDKLDITALLPTS  162
            A+  F   +      T    Q Q +  YY  EF      + P ER   ++L +T+L P +
Sbjct  80   AMEEFKQAYKDFPQLTEDGRQPQELQRYYQQEFGRQFDRLNPKERINTERL-LTSLSPQA  138

Query  163  PA--QRYLQAYYTAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLL  220
             A  Q Y+ A+   P   ++D  +L +AGDGS +S  + +++ +  + + +F Y D  L+
Sbjct  139  LALQQSYI-AFNPNPL-GEKD--KLLNAGDGSQYSQLHQEYHPHISDFLQKFSYYDIFLI  194

Query  221  D-TRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFKPYQPQLG  279
            D T GNIVY++ K+ D  T+++ GPY +S + +A+  A  A   D T I++FKPY P   
Sbjct  195  DDTTGNIVYSVFKELDFATSLIDGPYADSGIAEAFRAANRAGNRDLTVISNFKPYLPSYM  254

Query  280  VPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGPDSLMR  339
             P A++ +P+    +  GVL    PID+IN IMT +  W ++G+G   E YL      M+
Sbjct  255  GPAAFIASPIYQDTQKIGVLIFQAPIDEINAIMTFNHNWASSGLGDSGEAYLIDESQKMQ  314

Query  340  SDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTL-LQPVATEGLRAAQRGQTGTVT  398
            S SR  L+D   Y   + ++G S   VN AI    T++ LQ V + G+RAA  G+ G   
Sbjct  315  SVSRFLLEDKPAYLAALSSSGVSPKEVN-AIDTKNTSIGLQKVDSPGVRAALAGEHGFAI  373

Query  399  STDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVLVTVGIIVVICV  458
              DY     L AYAPL++   +L  +IL+  + +EAFA+ +  +  +   ++ II+++  
Sbjct  374  FPDYRNVEVLSAYAPLDIEGVEL--AILSEIDVAEAFASQSVLATNITTWSLVIILLLVS  431

Query  459  ASMLI----AHAMVRPIRRLEVGTQKI--SAGDYEVNIPVKSRDEIGDLTAAFNEMSRNL  512
            AS LI    A  + +PI  +     +I  + GD    I    RDE G L   FN     +
Sbjct  432  ASSLIGWVVAGQITKPINTVVNSLNQIAEAGGDLTQRIDSTRRDETGRLAVGFNGFVSKI  491

Query  513  QT  514
            QT
Sbjct  492  QT  493


>gi|254506531|ref|ZP_05118672.1| methyl-accepting chemotaxis protein [Vibrio parahaemolyticus 
16]
 gi|219550404|gb|EED27388.1| methyl-accepting chemotaxis protein [Vibrio parahaemolyticus 
16]
Length=779

 Score =  207 bits (526),  Expect = 8e-51, Method: Compositional matrix adjust.
 Identities = 134/453 (30%), Positives = 226/453 (50%), Gaps = 15/453 (3%)

Query  71   AYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQ  130
            A E+L  +RE +K  +E  F  +   L+     + V DA+  F+  F Q    +++    
Sbjct  51   ATEQLISVREIKKNEIELYFEQIRGQLITTAHSVGVQDAITEFSQAFAQYPIESVTERDH  110

Query  131  QAIVNYYNNEFITPVERTTGDKL--DITALLPTSPAQRYLQAYY--TAPF-TSDQDAMRL  185
             A+  YY ++F      +   +   ++  L   SP  + LQA Y  T P    D+  +  
Sbjct  111  SALERYYQSQFGATYRASNSGRSANEMQKLSMISPLGKALQARYIGTNPNPLGDKHQLIA  170

Query  186  DDAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPY  245
            D  G  + +   +A+++   +  + +F Y D  L++  G++VY++ K+ D  TN+LTGPY
Sbjct  171  DSLG--TRYDEVHAKYHPSIKGFLEQFGYYDIFLVNPNGDVVYSVFKELDYATNLLTGPY  228

Query  246  RESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPI  305
              S +  A+ +AL  +   F  + DF PY P      +++ +P++ G  T GVL   +P+
Sbjct  229  AGSGIAKAFSQALSMSDGQF-HLEDFAPYYPSYQAAASFISSPIKQGSTTLGVLIFQMPV  287

Query  306  DKINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDV  365
            D+IN IMT +  W  AG+G   E+YL GPD L+RS+SR  ++D + Y K ++ +G S  +
Sbjct  288  DEINNIMTFNGNWSNAGLGESGESYLVGPDGLLRSESRFLMEDADNYYKTMLNSGVSNTI  347

Query  366  VNRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSI  425
            + +    G     QPV T   ++A RGQ+G+    DY G   L AYAP+N   + L W I
Sbjct  348  IEQIKGKGSAIGRQPVTTSTSKSALRGQSGSDVVVDYRGEDVLSAYAPVNA--AGLSWGI  405

Query  426  LATRNDSEAFAAVASFSRALVLVTVG----IIVVICVASMLIAHAMVRPIRRLEVGTQKI  481
            +   +  EA   V S   A++   +     I+ +  V S  +  ++  PI+      Q+I
Sbjct  406  VTEIDKHEALKDVDSLINAMIFTVLSSIVVIVFIAIVISYFLGRSIAWPIKLASERIQQI  465

Query  482  SA-GDYEVNIPVKSRDEIGDLTAAFNEMSRNLQ  513
            S   D    + V  +DE+ +L  + N +  +LQ
Sbjct  466  SENNDLTQRLEVAGKDEMTELALSLNGLFTHLQ  498


>gi|320158661|ref|YP_004191039.1| methyl-accepting chemotaxis protein [Vibrio vulnificus MO6-24/O]
 gi|319933973|gb|ADV88836.1| methyl-accepting chemotaxis protein [Vibrio vulnificus MO6-24/O]
Length=770

 Score =  206 bits (524),  Expect = 1e-50, Method: Compositional matrix adjust.
 Identities = 134/452 (30%), Positives = 222/452 (50%), Gaps = 13/452 (2%)

Query  71   AYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQ  130
            A ++L  +RE +K  +E+ F  +   +      +   DA+  FT  F       I+    
Sbjct  42   ASQQLVSVREIKKSEIESYFEQIHYQVETLADDIATKDAMKAFTQAFQTYPSQQIASQDV  101

Query  131  QAIVNYYNNEFITPVERTTGDKL--DITALLPTSPAQRYLQAYYTA--PFTSDQDAMRLD  186
             A+ NYY+N+F           +  +I+ L       + LQA Y A  P    +    L 
Sbjct  102  NALRNYYSNQFGQKYRELNEGAVANEISMLDQIGEVGKALQARYIAINPNPLGEKHQYLS  161

Query  187  DAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYR  246
            D   G+ +   +A+++   +  +  F Y D   +D  GN+VY++ K+ D  TN+  GPY 
Sbjct  162  DTL-GTTYDQIHAKYHPSIKHFLEAFGYYDIFFVDNDGNVVYSVFKELDFATNLKQGPYS  220

Query  247  ESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPID  306
             + + +AY KA   N  D  ++ DFKPY P      +++  P+  G    GVL   +P+D
Sbjct  221  NTGIAEAYRKAAALNK-DQYYLDDFKPYYPSYEAAASFIATPIMEGDSRLGVLIFQMPVD  279

Query  307  KINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVV  366
             IN IMT    W A+G+G   ETYL GPD  MRS SR  L+ P++Y   + +AG S  ++
Sbjct  280  VINDIMTFKGNWAASGLGESGETYLIGPDKKMRSQSRFLLEAPDDYLAVMKSAGVSPQLL  339

Query  367  NRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSIL  426
             +    G T   Q + ++  R A  G++G     DY G + + AY+P+ V  + L W+IL
Sbjct  340  TQIASKGSTIGRQEIDSDAARNALMGRSGFEIIDDYRGVQVMSAYSPVTV--AGLKWAIL  397

Query  427  ATRNDSEAFAAVA----SFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKIS  482
               +  EA   +A    S    +++  VGIIVV  + S ++ +++ RPIR      ++I 
Sbjct  398  TEIDYDEALQDLALLEDSVRNTVLMSIVGIIVVSVLLSYVLGNSISRPIRLACEKVERIC  457

Query  483  A-GDYEVNIPVKSRDEIGDLTAAFNEMSRNLQ  513
               D    + V+ +DE+ +L+++ N +  +LQ
Sbjct  458  GNNDLTERLDVQGKDEVTELSSSLNHLFSHLQ  489


>gi|335043473|ref|ZP_08536500.1| methyl-accepting chemotaxis sensory transducer [Methylophaga 
aminisulfidivorans MP]
 gi|333790087|gb|EGL55969.1| methyl-accepting chemotaxis sensory transducer [Methylophaga 
aminisulfidivorans MP]
Length=777

 Score =  206 bits (524),  Expect = 1e-50, Method: Compositional matrix adjust.
 Identities = 144/508 (29%), Positives = 243/508 (48%), Gaps = 38/508 (7%)

Query  31   RFRASIQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYERLTQLRESQKRAVETLF  90
            + +  I    +V+ L   ++S A    I       +LR  + ERL  LR  +K  +   F
Sbjct  2    KIKQKITLAAIVIALTPILISTALTNYIATNESSIALRELSQERLISLRNVKKNQIRDYF  61

Query  91   SDLTNSLVIYERGLTVVDAVVRFTAGFDQLADAT---ISPAQQQAIVNYYNNEFITPVER  147
            + + N L        +  A+          A+        + +Q +  YY+  F    E 
Sbjct  62   ATIKNQLTNLANSSLITQALGDLNTAAQNYANDIGEYNKASLRQHVKTYYDTTFSQRYES  121

Query  148  TTG-----------DKLDITALLPTSPAQRYLQAYYT----APFTSDQDAMRLDDAGDGS  192
              G            KLD+  L         LQ  Y     AP     D ++ DD   GS
Sbjct  122  LNGVKPPVNMDDVLSKLDVNGLA--------LQQTYIVDNPAPLGKKDDLVQADD---GS  170

Query  193  AWSAANAQFNSYFREIVTRFDYDDAVLLDT-RGNIVYTLSKDPDLGTNILTGPYRESNLR  251
            ++++ +A+++ Y ++ + +F Y D  L+D   G +VY++ K+ D  T++  GPY  + L 
Sbjct  171  SYASYHAKYHPYLKDFLEKFGYYDIFLVDADTGMVVYSVFKELDYATSLKNGPYANTALG  230

Query  252  DAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKI  311
             A+ KAL     +   + D+ PY P    P +++ AP+   G  +GVL   +P+D+IN+I
Sbjct  231  QAFNKALEMGPDEQVAVVDYAPYLPSYESPASFMAAPISLNGSKKGVLIFQMPVDRINQI  290

Query  312  MTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQ  371
            MT +++W  AG+G   ETYL GPD  +RS+SR  ++D   Y + +       +     I+
Sbjct  291  MTFEKKWMEAGLGDSGETYLVGPDKRLRSESRFLVEDKAAYLEMLTKTQVIDEKSRNLIE  350

Query  372  FGGTTL-LQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRN  430
              G+ L + P+ + G+  A  G++G    TDY G+  L AYAPL++  + L+W+ILA  +
Sbjct  351  RKGSALGILPLNSHGVEDALAGKSGFDIITDYRGTHVLSAYAPLDI--AGLNWAILAEID  408

Query  431  DSEAFAAVASFSRALVLVTVGIIVVICVASMLIA----HAMVRPIRRLEVGTQKISAG-D  485
            ++EAFA     S +L L  + I+VVI + ++L A    + +  PI ++      ++   D
Sbjct  409  EAEAFAPANQLSNSLWLYGLSILVVIALLAVLFAVKASNLISTPILQISNFISGVAKDLD  468

Query  486  YEVNIPVKSRDEIGDLTAAFNEMSRNLQ  513
                + +K  DEIGD + A N M   +Q
Sbjct  469  LTARLDMKRTDEIGDASKALNNMLITMQ  496


>gi|343498784|ref|ZP_08736800.1| methyl-accepting chemotaxis protein [Vibrio tubiashii ATCC 19109]
 gi|342823884|gb|EGU58472.1| methyl-accepting chemotaxis protein [Vibrio tubiashii ATCC 19109]
Length=770

 Score =  204 bits (520),  Expect = 3e-50, Method: Compositional matrix adjust.
 Identities = 143/491 (30%), Positives = 239/491 (49%), Gaps = 17/491 (3%)

Query  36   IQSKLMVLLLLTSIVSVAAIAAIVYQSGRTSLRAAAYER----LTQLRESQKRAVETLFS  91
            I +K+++   L   ++V A   IV          A +ER    L  +RE +K  +E+ F 
Sbjct  3    IATKIVLASTLLCTLAVVATGVIVGWRSSGLSEQALFERATSQLISVREIKKNEIESYFK  62

Query  92   DLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTG-  150
             ++  +V     + V DA+  F+  F       +S +    + +YY   F    +   G 
Sbjct  63   HISGQVVTTANSVGVKDAMGAFSEAFKSYPIEQVSQSDIGQLQSYYQANFGATYKGANGG  122

Query  151  -DKLDITALLPTSPAQRYLQAYY--TAPFTSDQDAMRLDDAGDGSAWSAANAQFNSYFRE  207
                ++  L   SP  + LQA Y  T P    +    + D+  G+ + + +A ++   + 
Sbjct  123  ASANEMQKLNALSPLSKALQARYIGTNPNPLGEKHNLMSDS-LGTEYDSVHATYHPSIKG  181

Query  208  IVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTW  267
             +  F Y D  L+D  GNIVY++ K+ D  TN+ +GPY  S +  A+  AL  +A  +  
Sbjct  182  FLEEFGYYDIFLVDVDGNIVYSVFKELDYATNLNSGPYANSGIAKAFKNALNLSANQY-H  240

Query  268  ITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGT  327
            + DF PY P      +++  PV+   +T GVL   +P+D+IN+IMT +  W  AG+G   
Sbjct  241  LEDFYPYYPSYEAAASFIATPVKKSNQTLGVLIFQMPVDEINRIMTFNSNWSFAGLGESG  300

Query  328  ETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLR  387
            ETYL G D L+RS+SR  +++P+ Y   +  AG S  V+ +          QPVAT   +
Sbjct  301  ETYLVGQDGLLRSESRFLMENPDSYFAALKEAGVSQSVLAQIEGKSSAIGRQPVATATSK  360

Query  388  AAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFSRALVL  447
            AA +GQ+G+   TDY G   L AY+P+N   + L W I+   +  EA   + +   +L +
Sbjct  361  AALKGQSGSDIVTDYRGVEVLSAYSPVNA--AGLTWGIVTDIDKHEALEDLETLISSLAM  418

Query  448  -VTVGIIVVICVA---SMLIAHAMVRPIRRLEVGTQKISA-GDYEVNIPVKSRDEIGDLT  502
             V   I++V+ +A   S L+ +++ +PI+      Q I    D    +    +DE+ DL 
Sbjct  419  TVITSIVIVVALAVFISYLLGNSIAKPIKLASEKVQWIGKNNDLTQRLEESGKDEMTDLA  478

Query  503  AAFNEMSRNLQ  513
             + N +  +LQ
Sbjct  479  ISLNSLFAHLQ  489


>gi|330448376|ref|ZP_08312024.1| HAMP domain protein [Photobacterium leiognathi subsp. mandapamensis 
svers.1.1.]
 gi|328492567|dbj|GAA06521.1| HAMP domain protein [Photobacterium leiognathi subsp. mandapamensis 
svers.1.1.]
Length=768

 Score =  204 bits (520),  Expect = 4e-50, Method: Compositional matrix adjust.
 Identities = 140/483 (29%), Positives = 245/483 (51%), Gaps = 23/483 (4%)

Query  41   MVLLLLTSIVSVAAIAAIVYQSGRTSLRAA---AYERLTQLRESQKRAVETLFSDLTNSL  97
            + L +L +   V +   I ++S   S +A    A E+L  +RE +K  +E  F+     +
Sbjct  9    LTLSVLCACCVVLSGIYIAWKSAAISQQALYDRAIEQLISIREIKKTEIENHFNTTATLI  68

Query  98   VIYERGLTVVDAVVRFTAGFDQLADATISPAQQQAIVNYYNNEFITPVERTTGDKLDITA  157
              +    ++  A+ RF AGF+   +  I  A +QA++ +Y  +F   + R    +  I+ 
Sbjct  69   GTFSSDPSIKQAMQRFNAGFNSYPNQDIVMADKQALLQFYQEQF-AALYRDKNKEATISN  127

Query  158  LLPT-SPAQRYLQAYYTAPFTSDQDAMR--LDDAGDGSAWSAANAQFNSYFREIVTRFDY  214
            +    S     LQ+ Y A   S++   +  LD+    + +   +  F+   R  +  F +
Sbjct  128  IYEQLSDTAVSLQSRYIAN-NSNKLGQKHFLDNDTLNTDYDKTHQVFHPVLRHYLESFGF  186

Query  215  DDAVLLDTRGNIVYTLSKDPDLGTNILTGPYRESNLRDAYLKALGANAVDFTWITDFKPY  274
             D  L+D +GN+VY++ K+ D  TN+  GP++ S L +AY  AL  +  + T +TDFKPY
Sbjct  187  YDIFLVDNQGNVVYSVFKEVDFATNLQQGPFKNSGLANAYHGALKLSDGEVT-LTDFKPY  245

Query  275  QPQLGVPTAWLVAPVEAGGKTQGVLALPLPIDKINKIMTADRQWQAAGMGSGTETYLAGP  334
             P   +P+++L  P+    K  G + +  PID IN IMT D+ W  AG+G   E YL G 
Sbjct  246  TPSFELPSSFLSTPIFDNQKRIGYMIIQTPIDAINNIMTFDQNWNKAGLGKSGEIYLVGM  305

Query  335  DSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVVNRAIQFGGTTLLQPVATEGLRAAQRGQT  394
            DS +RS SR F++D + Y + + A   S +V++   +       QPV T  ++ A+ G+T
Sbjct  306  DSTLRSQSRFFIEDKQAYLQTLQANNISSNVIDNISKKDTAIGFQPVNTSSVQFARDGKT  365

Query  395  GTVTSTDYTGSRELEAYAPLNVPDSDLHWSILATRNDSEAFAAVASFS----RALVLVTV  450
            G+   TDY     L AYAP+ + +   HW I++  + +EA A V++      +A+ + +V
Sbjct  366  GSHAITDYRDIAVLSAYAPITLLNQ--HWMIISEIDKAEALADVSALKTQLYKAVAICSV  423

Query  451  GIIVVICVASMLIAHAMVRPIRRLEVGTQKISAGDYEVNIPVK-----SRDEIGDLTAAF  505
             ++++    S  I  ++ +PI+ L   ++KI A     N+  +        E+ DL+ +F
Sbjct  424  LLLLLAAFFSYFIGESIAKPIKIL---SKKIIAISDNKNLSARLTIRNGGSEVNDLSTSF  480

Query  506  NEM  508
            N+ 
Sbjct  481  NQF  483


>gi|27366778|ref|NP_762305.1| methyl-accepting chemotaxis protein [Vibrio vulnificus CMCP6]
 gi|27358345|gb|AAO07295.1|AE016809_57 Methyl-accepting chemotaxis protein [Vibrio vulnificus CMCP6]
Length=770

 Score =  204 bits (519),  Expect = 4e-50, Method: Compositional matrix adjust.
 Identities = 136/452 (31%), Positives = 222/452 (50%), Gaps = 13/452 (2%)

Query  71   AYERLTQLRESQKRAVETLFSDLTNSLVIYERGLTVVDAVVRFTAGFDQLADATISPAQQ  130
            A ++L  +RE +K  +E+ F  +   +      +   DA+  FT  F       I+    
Sbjct  42   ASQQLVSVREIKKSEIESYFEQIHYQVETLADDIATKDAMKAFTQAFQTYPSQQIASQDV  101

Query  131  QAIVNYYNNEFITPV-ERTTGDKL-DITALLPTSPAQRYLQAYYTA--PFTSDQDAMRLD  186
             A+ NYY+N+F     E   G    +I+ L       + LQA Y A  P    +    L 
Sbjct  102  NALRNYYSNQFGQKYRELNEGAAANEISMLDQIGEVGKALQARYIAINPNPLGEKHQYLS  161

Query  187  DAGDGSAWSAANAQFNSYFREIVTRFDYDDAVLLDTRGNIVYTLSKDPDLGTNILTGPYR  246
            D   G+ +   +A+++   +  +  F Y D   +D  GN+VY++ K+ D  TN+  GPY 
Sbjct  162  DTL-GTTYDQIHAKYHPSIKHFLEAFGYYDIFFVDNDGNVVYSVFKELDFATNLKQGPYS  220

Query  247  ESNLRDAYLKALGANAVDFTWITDFKPYQPQLGVPTAWLVAPVEAGGKTQGVLALPLPID  306
             + + +AY KA   N  D  ++ DFKPY P      +++  P+  G    GVL   +P+D
Sbjct  221  NTGIAEAYRKAAALNK-DQYYLDDFKPYYPSYEAAASFIATPIMEGDSRLGVLIFQMPVD  279

Query  307  KINKIMTADRQWQAAGMGSGTETYLAGPDSLMRSDSRLFLQDPEEYRKQVVAAGTSLDVV  366
             IN IMT    W A+G+G   E+YL GPD  MRS SR  L+ P++Y   + +AG S  ++
Sbjct  280  VINNIMTFKGNWAASGLGESGESYLIGPDKKMRSQSRFLLEAPDDYLAVMKSAGVSPQLL  339

Query  367  NRAIQFGGTTLLQPVATEGLRAAQRGQTGTVTSTDYTGSRELEAYAPLNVPDSDLHWSIL  426
             +    G T   Q +  +  R A  G++G     DY G + + AY+P+ V  + L W+IL
Sbjct  340  AQIASKGSTIGRQEIDGDAARNALMGRSGFEIIDDYRGVQVMSAYSPVTV--AGLKWAIL  397

Query  427  ATRNDSEAFAAVA----SFSRALVLVTVGIIVVICVASMLIAHAMVRPIRRLEVGTQKIS  482
               +  EA   +A    S    +++  VGIIVV  + S ++ +++ RPIR      ++I 
Sbjct  398  TEIDYDEALQDLAILEDSVRNTVLMSIVGIIVVSVLLSYVLGNSISRPIRLACEKVERIC  457

Query  483  A-GDYEVNIPVKSRDEIGDLTAAFNEMSRNLQ  513
               D    + V+ +DE+ +L+A+ N +  +LQ
Sbjct  458  GNNDLTERLDVQGKDEVTELSASLNHLFSHLQ  489



Lambda     K      H
   0.318    0.133    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 1737992751286


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40