BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2459 Length=508 Score E Sequences producing significant alignments: (Bits) Value gi|253798462|ref|YP_003031463.1| membrane transporter [Mycobacte... 1001 0.0 gi|254232593|ref|ZP_04925920.1| hypothetical protein TBCG_02400 ... 1001 0.0 gi|15841983|ref|NP_337020.1| drug transporter [Mycobacterium tub... 1001 0.0 gi|15609596|ref|NP_216975.1| integral membrane transport protein... 999 0.0 gi|31793640|ref|NP_856133.1| integral membrane transport protein... 998 0.0 gi|307085143|ref|ZP_07494256.1| conserved membrane transporter [... 994 0.0 gi|308232137|ref|ZP_07415066.2| conserved membrane transporter [... 988 0.0 gi|294994433|ref|ZP_06800124.1| membrane transporter [Mycobacter... 894 0.0 gi|183983780|ref|YP_001852071.1| integral membrane transport pro... 796 0.0 gi|118618990|ref|YP_907322.1| integral membrane transport protei... 783 0.0 gi|240169656|ref|ZP_04748315.1| integral membrane transport prot... 715 0.0 gi|183983622|ref|YP_001851913.1| integral membrane transport pro... 379 5e-103 gi|31793517|ref|NP_856010.1| integral membrane transport protein... 370 3e-100 gi|289443850|ref|ZP_06433594.1| drug transporter [Mycobacterium ... 370 3e-100 gi|15841836|ref|NP_336873.1| drug transporter [Mycobacterium tub... 370 4e-100 gi|298525817|ref|ZP_07013226.1| conserved integral membrane tran... 370 4e-100 gi|15609470|ref|NP_216849.1| integral membrane transport protein... 366 6e-99 gi|145594704|ref|YP_001159001.1| EmrB/QacA family drug resistanc... 303 3e-80 gi|159037939|ref|YP_001537192.1| EmrB/QacA family drug resistanc... 282 8e-74 gi|118617132|ref|YP_905464.1| integral membrane transport protei... 261 2e-67 gi|329934688|ref|ZP_08284729.1| efflux membrane protein [Strepto... 247 3e-63 gi|29832191|ref|NP_826825.1| efflux membrane protein [Streptomyc... 234 2e-59 gi|288918903|ref|ZP_06413246.1| drug resistance transporter, Emr... 233 8e-59 gi|302560756|ref|ZP_07313098.1| drug resistance transporter, Emr... 232 1e-58 gi|254382912|ref|ZP_04998268.1| efflux membrane protein [Strepto... 230 5e-58 gi|294629228|ref|ZP_06707788.1| EmrB/QacA family drug resistance... 230 6e-58 gi|291439775|ref|ZP_06579165.1| efflux protein [Streptomyces gha... 228 1e-57 gi|337765578|emb|CCB74287.1| putative efflux membrane protein [S... 226 6e-57 gi|32141172|ref|NP_733574.1| efflux protein [Streptomyces coelic... 226 8e-57 gi|298246882|ref|ZP_06970687.1| drug resistance transporter, Emr... 224 2e-56 gi|121611491|ref|YP_999298.1| EmrB/QacA family drug resistance t... 224 3e-56 gi|296136482|ref|YP_003643724.1| major facilitator superfamily M... 223 6e-56 gi|256391255|ref|YP_003112819.1| drug resistance transporter Emr... 222 1e-55 gi|298251605|ref|ZP_06975408.1| drug resistance transporter, Emr... 222 1e-55 gi|297199530|ref|ZP_06916927.1| efflux protein [Streptomyces svi... 220 5e-55 gi|298251556|ref|ZP_06975359.1| drug resistance transporter, Emr... 219 7e-55 gi|345015034|ref|YP_004817388.1| EmrB/QacA subfamily drug resist... 219 8e-55 gi|297194492|ref|ZP_06911890.1| efflux membrane protein [Strepto... 219 9e-55 gi|229490123|ref|ZP_04383971.1| efflux membrane protein [Rhodoco... 218 1e-54 gi|294812525|ref|ZP_06771168.1| Efflux membrane protein [Strepto... 217 4e-54 gi|254389019|ref|ZP_05004249.1| efflux membrane protein [Strepto... 217 4e-54 gi|338778012|gb|EGP42499.1| drug resistance MFS transporter, dru... 216 7e-54 gi|158318319|ref|YP_001510827.1| EmrB/QacA family drug resistanc... 214 3e-53 gi|157371058|ref|YP_001479047.1| major facilitator transporter [... 214 3e-53 gi|302534307|ref|ZP_07286649.1| efflux protein [Streptomyces sp.... 213 5e-53 gi|226304701|ref|YP_002764659.1| drug resistance efflux protein ... 212 1e-52 gi|107027637|ref|YP_625148.1| major facilitator transporter [Bur... 211 2e-52 gi|296117263|ref|ZP_06835855.1| drug resistance transporter, Emr... 211 3e-52 gi|290960586|ref|YP_003491768.1| major facilitator transporter [... 210 5e-52 gi|302551271|ref|ZP_07303613.1| efflux protein [Streptomyces vir... 209 8e-52 >gi|253798462|ref|YP_003031463.1| membrane transporter [Mycobacterium tuberculosis KZN 1435] gi|308372238|ref|ZP_07427935.2| conserved membrane transporter [Mycobacterium tuberculosis SUMu004] gi|253319965|gb|ACT24568.1| conserved membrane transporter [Mycobacterium tuberculosis KZN 1435] gi|308333916|gb|EFP22767.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu004] gi|339298967|gb|AEJ51077.1| integral membrane transport protein [Mycobacterium tuberculosis CCDC5180] Length=538 Score = 1001 bits (2589), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/508 (100%), Positives = 508/508 (100%), Gaps = 0/508 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM Sbjct 31 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 90 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL Sbjct 91 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 150 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL Sbjct 151 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 210 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL Sbjct 211 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 270 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG Sbjct 271 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 330 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT Sbjct 331 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 390 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL Sbjct 391 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 450 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI Sbjct 451 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 510 Query 481 KLALGGAAVLLTGAFVLGWTRFPRTPAS 508 KLALGGAAVLLTGAFVLGWTRFPRTPAS Sbjct 511 KLALGGAAVLLTGAFVLGWTRFPRTPAS 538 >gi|254232593|ref|ZP_04925920.1| hypothetical protein TBCG_02400 [Mycobacterium tuberculosis C] gi|254365235|ref|ZP_04981281.1| conserved integral membrane transport protein [Mycobacterium tuberculosis str. Haarlem] gi|308369723|ref|ZP_07418839.2| conserved membrane transporter [Mycobacterium tuberculosis SUMu002] 10 more sequence titles Length=532 Score = 1001 bits (2588), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/508 (100%), Positives = 508/508 (100%), Gaps = 0/508 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM Sbjct 25 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 84 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL Sbjct 85 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 144 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL Sbjct 145 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 204 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL Sbjct 205 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 264 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG Sbjct 265 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 324 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT Sbjct 325 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 384 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL Sbjct 385 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 444 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI Sbjct 445 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 504 Query 481 KLALGGAAVLLTGAFVLGWTRFPRTPAS 508 KLALGGAAVLLTGAFVLGWTRFPRTPAS Sbjct 505 KLALGGAAVLLTGAFVLGWTRFPRTPAS 532 >gi|15841983|ref|NP_337020.1| drug transporter [Mycobacterium tuberculosis CDC1551] gi|148823659|ref|YP_001288413.1| integral membrane transport protein [Mycobacterium tuberculosis F11] gi|289553750|ref|ZP_06442960.1| conserved membrane transporter [Mycobacterium tuberculosis KZN 605] 18 more sequence titles Length=523 Score = 1001 bits (2587), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/508 (100%), Positives = 508/508 (100%), Gaps = 0/508 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM Sbjct 16 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 75 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL Sbjct 76 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 135 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL Sbjct 136 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 195 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL Sbjct 196 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 255 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG Sbjct 256 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 315 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT Sbjct 316 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 375 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL Sbjct 376 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 435 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI Sbjct 436 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 495 Query 481 KLALGGAAVLLTGAFVLGWTRFPRTPAS 508 KLALGGAAVLLTGAFVLGWTRFPRTPAS Sbjct 496 KLALGGAAVLLTGAFVLGWTRFPRTPAS 523 >gi|15609596|ref|NP_216975.1| integral membrane transport protein [Mycobacterium tuberculosis H37Rv] gi|121638342|ref|YP_978566.1| putative integral membrane transport protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|148662294|ref|YP_001283817.1| putative transmembrane transport protein [Mycobacterium tuberculosis H37Ra] 33 more sequence titles Length=508 Score = 999 bits (2584), Expect = 0.0, Method: Compositional matrix adjust. Identities = 508/508 (100%), Positives = 508/508 (100%), Gaps = 0/508 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM Sbjct 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL Sbjct 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL Sbjct 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL Sbjct 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG Sbjct 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT Sbjct 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL Sbjct 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI Sbjct 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 Query 481 KLALGGAAVLLTGAFVLGWTRFPRTPAS 508 KLALGGAAVLLTGAFVLGWTRFPRTPAS Sbjct 481 KLALGGAAVLLTGAFVLGWTRFPRTPAS 508 >gi|31793640|ref|NP_856133.1| integral membrane transport protein [Mycobacterium bovis AF2122/97] gi|31619233|emb|CAD97347.1| PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN [Mycobacterium bovis AF2122/97] Length=508 Score = 998 bits (2579), Expect = 0.0, Method: Compositional matrix adjust. Identities = 507/508 (99%), Positives = 508/508 (100%), Gaps = 0/508 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLG+AAVLM Sbjct 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGIAAVLM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL Sbjct 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL Sbjct 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL Sbjct 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG Sbjct 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT Sbjct 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL Sbjct 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI Sbjct 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 Query 481 KLALGGAAVLLTGAFVLGWTRFPRTPAS 508 KLALGGAAVLLTGAFVLGWTRFPRTPAS Sbjct 481 KLALGGAAVLLTGAFVLGWTRFPRTPAS 508 >gi|307085143|ref|ZP_07494256.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu012] gi|308365322|gb|EFP54173.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu012] gi|323718965|gb|EGB28115.1| membrane transporter [Mycobacterium tuberculosis CDC1551A] Length=601 Score = 994 bits (2569), Expect = 0.0, Method: Compositional matrix adjust. Identities = 506/506 (100%), Positives = 506/506 (100%), Gaps = 0/506 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM Sbjct 25 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 84 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL Sbjct 85 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 144 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL Sbjct 145 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 204 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL Sbjct 205 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 264 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG Sbjct 265 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 324 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT Sbjct 325 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 384 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL Sbjct 385 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 444 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI Sbjct 445 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 504 Query 481 KLALGGAAVLLTGAFVLGWTRFPRTP 506 KLALGGAAVLLTGAFVLGWTRFPRTP Sbjct 505 KLALGGAAVLLTGAFVLGWTRFPRTP 530 >gi|308232137|ref|ZP_07415066.2| conserved membrane transporter [Mycobacterium tuberculosis SUMu001] gi|308214889|gb|EFO74288.1| conserved membrane transporter [Mycobacterium tuberculosis SUMu001] Length=574 Score = 988 bits (2553), Expect = 0.0, Method: Compositional matrix adjust. Identities = 503/503 (100%), Positives = 503/503 (100%), Gaps = 0/503 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM Sbjct 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL Sbjct 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL Sbjct 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL Sbjct 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG Sbjct 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT Sbjct 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL Sbjct 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI Sbjct 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 Query 481 KLALGGAAVLLTGAFVLGWTRFP 503 KLALGGAAVLLTGAFVLGWTRFP Sbjct 481 KLALGGAAVLLTGAFVLGWTRFP 503 >gi|294994433|ref|ZP_06800124.1| membrane transporter [Mycobacterium tuberculosis 210] Length=508 Score = 894 bits (2311), Expect = 0.0, Method: Compositional matrix adjust. Identities = 476/508 (94%), Positives = 480/508 (95%), Gaps = 0/508 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MTPRQRLTVLA G V P+ ++ F + VAGYSLGMAAVLM Sbjct 1 MTPRQRLTVLARGWASSWVSWTSTSSMSHCPASKRCFTRANKVCSGPVAGYSLGMAAVLM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL Sbjct 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL Sbjct 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL Sbjct 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG Sbjct 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT Sbjct 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL Sbjct 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI Sbjct 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 Query 481 KLALGGAAVLLTGAFVLGWTRFPRTPAS 508 KLALGGAAVLLTGAFVLGWTRFPRTPAS Sbjct 481 KLALGGAAVLLTGAFVLGWTRFPRTPAS 508 >gi|183983780|ref|YP_001852071.1| integral membrane transport protein [Mycobacterium marinum M] gi|183177106|gb|ACC42216.1| conserved integral membrane transport protein [Mycobacterium marinum M] Length=524 Score = 796 bits (2055), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/504 (78%), Positives = 447/504 (89%), Gaps = 0/504 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MT RQRLTV ATGLGIFMVFVDVNIVNVALPSIQ+VFHTGEQGLQWAVAGYSLGMAA+LM Sbjct 1 MTRRQRLTVAATGLGIFMVFVDVNIVNVALPSIQRVFHTGEQGLQWAVAGYSLGMAAMLM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRR F G+ LFV SS+VCVLP++L +FT ARVIQGLGA+FISVLSLALL Sbjct 61 SCALLGDRYGRRRGFFVGLALFVASSVVCVLPINLGMFTAARVIQGLGASFISVLSLALL 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SH+FP+ RMKARAI++WMAIGMVGAASAPALGGLMV+ LGWRSVF VNVPLGAIV +LTL Sbjct 121 SHAFPDQRMKARAIADWMAIGMVGAASAPALGGLMVETLGWRSVFAVNVPLGAIVLVLTL 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 +GVDES+DP+PT+LDWVGQLT +P +A++AYTIIEAPRF ++S + +LLL LLW Sbjct 181 IGVDESRDPDPTELDWVGQLTFVPGIAVLAYTIIEAPRFQQRSVIVLTSLLLIIVALLWT 240 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 F+RHE RA FPL+DL+LF EP+YRSVLIVYFVVMSCFFGTLMVITQ FQNVRDLSPLHAG Sbjct 241 FIRHERRAPFPLIDLQLFTEPVYRSVLIVYFVVMSCFFGTLMVITQFFQNVRDLSPLHAG 300 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LMMLPVPAGFG+ASLLAG AVNKWGP+LPV+TCLAAM GL +F +M H +AL+GLT Sbjct 301 LMMLPVPAGFGMASLLAGAAVNKWGPRLPVVTCLAAMVTGLVLFVTAMGHVPALALMGLT 360 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 +FGAGAGG TPLLHLGMTKVDD RAGMAAG+LNLQRS+GGIFGVAFLG+I+AAWLGA L Sbjct 361 VFGAGAGGSVTPLLHLGMTKVDDHRAGMAAGLLNLQRSMGGIFGVAFLGSILAAWLGATL 420 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 P++M D++PDP+ R+IVVD IVDSANPHAHAAFIGP HRIT+AQE IV AAD+ F+ GI Sbjct 421 PDSMEDDLPDPVVRSIVVDTIVDSANPHAHAAFIGPRHRITSAQETNIVSAADSDFMQGI 480 Query 481 KLALGGAAVLLTGAFVLGWTRFPR 504 ++ALG A+VLL AFVLG RFPR Sbjct 481 RIALGCASVLLAAAFVLGLRRFPR 504 >gi|118618990|ref|YP_907322.1| integral membrane transport protein [Mycobacterium ulcerans Agy99] gi|118571100|gb|ABL05851.1| conserved integral membrane transport protein [Mycobacterium ulcerans Agy99] Length=554 Score = 783 bits (2023), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/502 (78%), Positives = 444/502 (89%), Gaps = 0/502 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MT RQRLTV ATGLGIFMVFVDVNIVNVALPSIQ+VFHTGEQGLQWAVAGYSLGMAA+LM Sbjct 31 MTRRQRLTVAATGLGIFMVFVDVNIVNVALPSIQRVFHTGEQGLQWAVAGYSLGMAAMLM 90 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRR F G+ LFV SS+VCVLP++L +FT ARVIQGL A+FISVLSLALL Sbjct 91 SCALLGDRYGRRRGFFVGLALFVASSVVCVLPINLGMFTAARVIQGLDASFISVLSLALL 150 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SH+FP+ RMKARAI++WMAIGMVGAASAPALGGLMV+ LGWRSVF V+VPLGAIV +LTL Sbjct 151 SHAFPDQRMKARAIADWMAIGMVGAASAPALGGLMVETLGWRSVFAVSVPLGAIVLVLTL 210 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 +GVDES+DP+PT+LDWVGQLT +P +A++AYTIIEAPRF ++S + +LLL LL Sbjct 211 IGVDESRDPDPTELDWVGQLTFVPGIAVLAYTIIEAPRFQQRSVIVLTSLLLIIVALLRT 270 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 F+RHE RA FPL+DL+LF EP+YRSVLIVYFVVMSCFFGTLMVITQ FQNVRDLSPLHAG Sbjct 271 FIRHERRAPFPLIDLQLFTEPVYRSVLIVYFVVMSCFFGTLMVITQFFQNVRDLSPLHAG 330 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LMMLPVPAGFG+ASLLAG AVNKWGP+LPV+TCLAAM GL +F +M H +AL+GLT Sbjct 331 LMMLPVPAGFGMASLLAGAAVNKWGPRLPVVTCLAAMVTGLVLFVTAMGHVPALALMGLT 390 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 +FGAGAGG TPLLHLGMTKVDD RAGMAAG+LNLQRS+GGIFGVAFLG+I+AAWLGA L Sbjct 391 VFGAGAGGSVTPLLHLGMTKVDDHRAGMAAGLLNLQRSMGGIFGVAFLGSILAAWLGATL 450 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 P++M D++PDP+ R+IVVD IVDSANPHAHAAFIGP HRIT+AQE IV AAD+ F+ GI Sbjct 451 PDSMEDDLPDPVVRSIVVDTIVDSANPHAHAAFIGPRHRITSAQETNIVSAADSDFMQGI 510 Query 481 KLALGGAAVLLTGAFVLGWTRF 502 ++ALG A+VLL AFVLG+ RF Sbjct 511 RIALGCASVLLAAAFVLGFRRF 532 >gi|240169656|ref|ZP_04748315.1| integral membrane transport protein [Mycobacterium kansasii ATCC 12478] Length=520 Score = 715 bits (1846), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/503 (71%), Positives = 411/503 (82%), Gaps = 1/503 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 MTPRQR+TV+ATGLGIFMVFVD+NIVNVALPSIQ V+ TGEQGLQWAVAGYSLGMAAVLM Sbjct 11 MTPRQRMTVVATGLGIFMVFVDINIVNVALPSIQAVYKTGEQGLQWAVAGYSLGMAAVLM 70 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 SCALLGDRYGRRR F G+ +F +S++C +PVSL + TVARV+QG+GAAFISVLSLALL Sbjct 71 SCALLGDRYGRRRGFFIGLGVFAAASMICAVPVSLGILTVARVVQGVGAAFISVLSLALL 130 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 SH+FP+P MKARAI+ WMAIG +GA SAPALGG++V+ +GWRSVF VNVPLGA VWLLT Sbjct 131 SHAFPDPGMKARAIAGWMAIGCIGAGSAPALGGILVEEMGWRSVFAVNVPLGAAVWLLTR 190 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 + V ES+DP+PTQLDW GQL PAVAL+AY IIEAPR DRQ G + LL A VLLW Sbjct 191 LSVTESKDPDPTQLDWPGQLMFAPAVALLAYAIIEAPRADRQP-GLMVILLSVAFVLLWF 249 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FV+HE RA FPL+DL+LF P+YRS L+VYFVVMSC+FGTLMVITQHFQNVR +PL AG Sbjct 250 FVQHERRAVFPLIDLQLFTHPVYRSALVVYFVVMSCYFGTLMVITQHFQNVRGFTPLQAG 309 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 L+MLPVP GFG+ASLLAGRAV WGP+LPVL CLAAM +GLA+F I++ PV + GL Sbjct 310 LLMLPVPVGFGIASLLAGRAVESWGPRLPVLICLAAMIVGLALFGIAIGRVMPVVVAGLA 369 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 +FGAGAGGCATPLLH+ MT+VDD RAGMAAG++NLQRSLG IFGVA LG+I+A WL AL Sbjct 370 LFGAGAGGCATPLLHIAMTEVDDHRAGMAAGLINLQRSLGSIFGVALLGSILAGWLSVAL 429 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 P + D I DP RA V+ +VD ANP AHAA IGPGH T+ QE IV AD F+ G+ Sbjct 430 PERLDDVISDPAERASVLSSVVDGANPRAHAAEIGPGHPTTSQQEQTIVRVADKEFIRGV 489 Query 481 KLALGGAAVLLTGAFVLGWTRFP 503 +LA+ GAAVLL+ A VLG RFP Sbjct 490 QLAVAGAAVLLSAALVLGVRRFP 512 >gi|183983622|ref|YP_001851913.1| integral membrane transport protein [Mycobacterium marinum M] gi|183176948|gb|ACC42058.1| conserved integral membrane transport protein [Mycobacterium marinum M] Length=518 Score = 379 bits (974), Expect = 5e-103, Method: Compositional matrix adjust. Identities = 226/504 (45%), Positives = 297/504 (59%), Gaps = 4/504 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 M Q LT+ ATGLG+FM+F+D IVNVALP IQ F GE GLQW VA YSLGMA +M Sbjct 1 MNRTQLLTIFATGLGLFMIFLDAFIVNVALPDIQNTFGVGEDGLQWVVAAYSLGMAVFIM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 S A L DRYGRRR ++ G+ LF + SI C L S+A+ T AR IQG GAA +SV SLAL+ Sbjct 61 SAATLADRYGRRRWYLMGIALFTLGSIACGLAPSIAMLTAARGIQGFGAATVSVTSLALV 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 S +FPNP+ KARAI W A+ VG A+ P LGGL+VD GWRS+F VNVP+G V LLT+ Sbjct 121 SAAFPNPKEKARAIGIWTAVASVGTATGPTLGGLLVDTWGWRSIFYVNVPMGVFVILLTV 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 V ES++ +LD GQ I V Y +IE P+ S + LL+ A V L Sbjct 181 GFVAESRNARAGRLDLSGQALFIVTVGAFVYAVIEGPQIGWTSP-LILTLLMTAAVGCAL 239 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 F+ E R+A P++DL LF + Y + V +G L++ TQ QNVR +P G Sbjct 240 FLWLEGRSADPMMDLTLFRDSSYALSIGTICTVFFAVYGMLLLTTQFLQNVRGYTPGATG 299 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LM+LP AG V S L G V + G ++ +L L + +GL S + + LVGL Sbjct 300 LMILPFSAGVAVVSPLVGSLVARVGARVLILIGLGLLMLGLLTLIASEHRSWALVLVGLG 359 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 G G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L Sbjct 360 FCGTGVALCLTPITTVAMTAVPPERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 + +PDP+ R + +VI+DSANP AH I P I D + +A + F+ GI Sbjct 420 EPHLEPAVPDPVQRHTIAEVIIDSANPRAHVGGIVPRREIV--HRDPVAIAEED-FIEGI 476 Query 481 KLALGGAAVLLTGAFVLGWTRFPR 504 ++A A L F+ GW FPR Sbjct 477 RVAFFIATASLGFVFLAGWRWFPR 500 >gi|31793517|ref|NP_856010.1| integral membrane transport protein [Mycobacterium bovis AF2122/97] gi|121638220|ref|YP_978444.1| putative integral membrane transport protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224990714|ref|YP_002645401.1| putative integral membrane transport protein [Mycobacterium bovis BCG str. Tokyo 172] gi|31619110|emb|CAD97222.1| PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN [Mycobacterium bovis AF2122/97] gi|121493868|emb|CAL72343.1| Probable conserved integral membrane transport protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224773827|dbj|BAH26633.1| putative integral membrane transport protein [Mycobacterium bovis BCG str. Tokyo 172] gi|341602258|emb|CCC64932.1| probable conserved integral membrane transport protein [Mycobacterium bovis BCG str. Moreau RDJ] Length=523 Score = 370 bits (950), Expect = 3e-100, Method: Compositional matrix adjust. Identities = 223/504 (45%), Positives = 303/504 (61%), Gaps = 4/504 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M Sbjct 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 S A L D YGRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+ Sbjct 61 SAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL Sbjct 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 V+ES + + D GQL I AV + Y +IE P+ S + +L A V L Sbjct 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTI-VMLWTAAVGCAL 239 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G Sbjct 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL Sbjct 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 + G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L Sbjct 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 + +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI Sbjct 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476 Query 481 KLALGGAAVLLTGAFVLGWTRFPR 504 ++AL A L F+ GW FPR Sbjct 477 RVALLVATATLAVVFLAGWRWFPR 500 >gi|289443850|ref|ZP_06433594.1| drug transporter [Mycobacterium tuberculosis T46] gi|289447974|ref|ZP_06437718.1| conserved membrane transporter [Mycobacterium tuberculosis CPHL_A] gi|289570466|ref|ZP_06450693.1| conserved membrane transporter [Mycobacterium tuberculosis T17] 9 more sequence titles Length=523 Score = 370 bits (950), Expect = 3e-100, Method: Compositional matrix adjust. Identities = 223/504 (45%), Positives = 303/504 (61%), Gaps = 4/504 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M Sbjct 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 S A L D YGRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+ Sbjct 61 SAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL Sbjct 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 V+ES + + D GQL I AV + Y +IE P+ S + +L A V L Sbjct 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTI-VMLWTAAVGCAL 239 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G Sbjct 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL Sbjct 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 + G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L Sbjct 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 + +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI Sbjct 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476 Query 481 KLALGGAAVLLTGAFVLGWTRFPR 504 ++AL A L F+ GW FPR Sbjct 477 RVALLVATATLAVVFLAGWRWFPR 500 >gi|15841836|ref|NP_336873.1| drug transporter [Mycobacterium tuberculosis CDC1551] gi|254232477|ref|ZP_04925804.1| hypothetical protein TBCG_02278 [Mycobacterium tuberculosis C] gi|254365113|ref|ZP_04981159.1| conserved integral membrane transport protein [Mycobacterium tuberculosis str. Haarlem] 12 more sequence titles Length=537 Score = 370 bits (949), Expect = 4e-100, Method: Compositional matrix adjust. Identities = 223/504 (45%), Positives = 303/504 (61%), Gaps = 4/504 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M Sbjct 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 S A L D YGRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+ Sbjct 61 SAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL Sbjct 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 V+ES + + D GQL I AV + Y +IE P+ S + +L A V L Sbjct 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTI-VMLWTAAVGCAL 239 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G Sbjct 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL Sbjct 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 + G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L Sbjct 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 + +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI Sbjct 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476 Query 481 KLALGGAAVLLTGAFVLGWTRFPR 504 ++AL A L F+ GW FPR Sbjct 477 RVALLVATATLAVVFLAGWRWFPR 500 >gi|298525817|ref|ZP_07013226.1| conserved integral membrane transport protein [Mycobacterium tuberculosis 94_M4241A] gi|298495611|gb|EFI30905.1| conserved integral membrane transport protein [Mycobacterium tuberculosis 94_M4241A] Length=537 Score = 370 bits (949), Expect = 4e-100, Method: Compositional matrix adjust. Identities = 223/504 (45%), Positives = 303/504 (61%), Gaps = 4/504 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M Sbjct 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 S A L D YGRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+ Sbjct 61 SAATLADLYGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL Sbjct 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 V+ES + + D GQL I AV + Y +IE P+ S + +L A V L Sbjct 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTI-VMLWTAAVGCAL 239 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G Sbjct 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL Sbjct 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 + G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L Sbjct 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 + +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI Sbjct 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476 Query 481 KLALGGAAVLLTGAFVLGWTRFPR 504 ++AL A L F+ GW FPR Sbjct 477 RVALLVATATLAVVFLAGWRWFPR 500 >gi|15609470|ref|NP_216849.1| integral membrane transport protein [Mycobacterium tuberculosis H37Rv] gi|148662161|ref|YP_001283684.1| putative integral membrane transport protein [Mycobacterium tuberculosis H37Ra] gi|148823534|ref|YP_001288288.1| integral membrane transport protein [Mycobacterium tuberculosis F11] 41 more sequence titles Length=537 Score = 366 bits (939), Expect = 6e-99, Method: Compositional matrix adjust. Identities = 222/504 (45%), Positives = 302/504 (60%), Gaps = 4/504 (0%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 M Q LT++ATGLG+FM+F+D IVNVALP IQ+ F GE GLQW VA YSLGMA +M Sbjct 1 MNRTQLLTLIATGLGLFMIFLDALIVNVALPDIQRSFAVGEDGLQWVVASYSLGMAVFIM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 S A L D GRRR ++ GV+LF + SI C L S+AV T AR QGLGAA +SV SLAL+ Sbjct 61 SAATLADLDGRRRWYLIGVSLFTLGSIACGLAPSIAVLTTARGAQGLGAAAVSVTSLALV 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 S +FP + KARAI W AI +G + P LGGL+VD GWRS+F VN+P+GA+V LTL Sbjct 121 SAAFPEAKEKARAIGIWTAIASIGTTTGPTLGGLLVDQWGWRSIFYVNLPMGALVLFLTL 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 V+ES + + D GQL I AV + Y +IE P+ S + +L A V L Sbjct 181 CYVEESCNERARRFDLSGQLLFIVAVGALVYAVIEGPQIGWTSVQTI-VMLWTAAVGCAL 239 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 FV E R++ P++DL LF + Y + V +G L++ TQ QNVR +P G Sbjct 240 FVWLERRSSNPMMDLTLFRDTSYALAIATICTVFFAVYGMLLLTTQFLQNVRGYTPSVTG 299 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLT 360 LM+LP A + S L G V + G ++P+L L + +GL + S + + LVGL Sbjct 300 LMILPFSAAVAIVSPLVGHLVGRIGARVPILAGLCMLMLGLLMLIFSEHRSSALVLVGLG 359 Query 361 IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAAL 420 + G+G C TP+ + MT V RAGMA+G+++ QR++G G A LG+++AAWL A L Sbjct 360 LCGSGVALCLTPITTVAMTAVPAERAGMASGIMSAQRAIGSTIGFAVLGSVLAAWLSATL 419 Query 421 PNTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVLAADAVFVSGI 480 + +PDP+ R ++ ++I+DSANP AH I P I + + V A+ F+ GI Sbjct 420 EPHLERAVPDPVQRHVLAEIIIDSANPRAHVGGIVPRRHI---EHRDPVAIAEEDFIEGI 476 Query 481 KLALGGAAVLLTGAFVLGWTRFPR 504 ++AL A L F+ GW FPR Sbjct 477 RVALLVATATLAVVFLAGWRWFPR 500 >gi|145594704|ref|YP_001159001.1| EmrB/QacA family drug resistance transporter [Salinispora tropica CNB-440] gi|145304041|gb|ABP54623.1| drug resistance transporter, EmrB/QacA subfamily [Salinispora tropica CNB-440] Length=524 Score = 303 bits (777), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 190/492 (39%), Positives = 283/492 (58%), Gaps = 4/492 (0%) Query 2 TPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMS 61 T Q+ T++A GLG+F+ DV + NVALP IQ + GE GLQW VA YS+GMA +M Sbjct 16 TRAQKWTIVAAGLGVFITLHDVLVANVALPRIQAFYGLGESGLQWIVASYSMGMAIAIMP 75 Query 62 CALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLS 121 A + DR+GRRR ++ V +F+V+S++ + + AV VAR +QG+ +A I+V +LAL+S Sbjct 76 AATVADRFGRRRLYLSAVVVFIVASVISGVTSTFAVMLVARGVQGVASAVITVSALALVS 135 Query 122 HSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTLV 181 +FP+ R + A+ + A+ VG A P LGG++ + WR VF VNVP+ + LTL Sbjct 136 ATFPHKRQRFFALGLFAAVADVGLALGPPLGGILTETASWRLVFFVNVPVAVLAVGLTLR 195 Query 182 GVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWLF 241 V ES++ +D GQL + V +T+I+ S +A +A V L F Sbjct 196 YVAESRESTRRVVDLPGQLLFVITVGAFTFTVIDGHDLGWGSPTILAT-FVAFAVGLAAF 254 Query 242 VRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGL 301 + E R+ P++DL+LFA YR + F M +G L+++TQ+FQNVR SP+ AGL Sbjct 255 IVRELRSRSPMMDLRLFASRAYRLGNMAIFFGMFTVYGALLIVTQYFQNVRLYSPIEAGL 314 Query 302 MMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLTI 361 ++LP S +AG + G +LP L + +GLA+ + + H+ ++G + Sbjct 315 LILPSSLASVAFSPVAGFIAARRGARLPALAGQVLLVVGLAVMVVGVAHSVVAVVLGFLL 374 Query 362 FGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAALP 421 GAG P+ L + V RAGMA+G++ QR LG G A LGTIV+ W+G AL Sbjct 375 LGAGLSLIIPPVQGLALNSVPVERAGMASGIVATQRGLGSTAGYAVLGTIVSVWVGIALD 434 Query 422 NTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIV---LAADAVFVS 478 ++ IPD RA VV+ IVD NP+A A +GPG + + D++ AD FV Sbjct 435 GDLSRTIPDRDERAAVVEQIVDDTNPNAFEAVVGPGRPVDHPESDQVTTIRTVADRTFVR 494 Query 479 GIKLALGGAAVL 490 G++L+LG AA++ Sbjct 495 GMQLSLGFAALV 506 >gi|159037939|ref|YP_001537192.1| EmrB/QacA family drug resistance transporter [Salinispora arenicola CNS-205] gi|157916774|gb|ABV98201.1| drug resistance transporter, EmrB/QacA subfamily [Salinispora arenicola CNS-205] Length=524 Score = 282 bits (722), Expect = 8e-74, Method: Compositional matrix adjust. Identities = 193/492 (40%), Positives = 279/492 (57%), Gaps = 4/492 (0%) Query 2 TPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMS 61 T Q+ T++A GLG+F+ DV + NVALP IQ + E GLQW VA YS+GMA +M Sbjct 16 TRAQKWTIVAAGLGMFITLHDVLVANVALPRIQSFYGLRESGLQWIVAAYSMGMAVAIMP 75 Query 62 CALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLS 121 A + DR+GRRR F+ V +F ++S+ AV AR +QG+ +A I+V +LAL+S Sbjct 76 AATMADRFGRRRLFLTAVVVFSLASVAAGATSVFAVMLAARAVQGVASAVITVSALALVS 135 Query 122 HSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTLV 181 +FP+ R + RA+ ++A+ +G A P LGG + + WR VF VNVP+ + LTL Sbjct 136 ATFPHKRQRFRALGFFVAVADIGLALGPPLGGFLAENASWRVVFFVNVPVAVVAVGLTLR 195 Query 182 GVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWLF 241 V ES++ +D GQL + V + +I+ S + A + A L+ Sbjct 196 YVAESRESTRRVVDLFGQLLFVVTVGAFTFAVIDGHDLGWGSPIILGAFTVFAAGLVAFI 255 Query 242 VRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGL 301 VR E R+ P++DL+LFA YR ++ F M +GTL+++TQ+FQNVR SPL AGL Sbjct 256 VR-ELRSRSPMMDLRLFAHRPYRLGIMAIFFGMFTVYGTLLIVTQYFQNVRLYSPLEAGL 314 Query 302 MMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALVGLTI 361 ++LP V S +AG + GP+LP LT + GL + + + + P +VG + Sbjct 315 LILPSSLAAVVLSPVAGFVAARRGPRLPALTGQFLVVSGLVVMVVGVSVSVPAVVVGFLL 374 Query 362 FGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAALP 421 GAG P+ L + V RAGMA+G++ QR LG G A LG IVA W+G AL Sbjct 375 LGAGLSLIIAPVQGLALNSVPVERAGMASGIVATQRGLGSTAGYAVLGMIVAVWVGIALD 434 Query 422 NTMADEIPDPIARAIVVDVIVDSANPHAHAAFIGPGHRITAAQEDEIVL---AADAVFVS 478 + ++ IPD RA VV IVD+ NP+A A +GPG I D++ AD FV Sbjct 435 SDLSRTIPDRDERATVVARIVDNTNPNAFEAVVGPGRPIAHPDPDQVTKIRAVADRTFVR 494 Query 479 GIKLALGGAAVL 490 G++L+LG AA++ Sbjct 495 GMQLSLGFAALV 506 >gi|118617132|ref|YP_905464.1| integral membrane transport protein [Mycobacterium ulcerans Agy99] gi|118569242|gb|ABL03993.1| conserved integral membrane transport protein [Mycobacterium ulcerans Agy99] Length=301 Score = 261 bits (667), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 147/296 (50%), Positives = 186/296 (63%), Gaps = 9/296 (3%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 M Q LT+ ATGLG+FM+F+D IVNVALP IQ F GE GLQW VA YSLGMA +M Sbjct 1 MNRTQLLTIFATGLGLFMIFLDAFIVNVALPDIQNTFGVGEDGLQWVVAAYSLGMAVFIM 60 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 S A L DRYGRRR ++ G+ LF + SI C L S+A+ T AR +QG GAA +SV SLAL+ Sbjct 61 SAATLADRYGRRRWYLMGIVLFTLGSIACGLAPSIAMLTAARGVQGFGAATVSVTSLALV 120 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 S +FPNP+ KARAI W A+ VG A+ P LGGL+VD GWRS+F VNVP+G V LLT+ Sbjct 121 SAAFPNPKEKARAIGIWTAVASVGTATGPTLGGLLVDTWGWRSIFYVNVPMGVFVILLTV 180 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL 240 V ES++ QLD GQ I V Y +IE P+ S + LL+ A V L Sbjct 181 GFVAESRNARAGQLDLSGQALFIVTVGAFVYAVIEGPQIGWTSP-LILTLLMTAIVGCAL 239 Query 241 FVRHEHRAAFPLVDLKLFAEPLYR----SVLIVYFVVMSCFFGTLMVITQHFQNVR 292 F+ E R+A P++DL LF + Y ++ V+F V +G L++ TQ NVR Sbjct 240 FLWLEGRSADPMMDLTLFRDSSYALSIGTICTVFFAV----YGMLLLTTQFLHNVR 291 >gi|329934688|ref|ZP_08284729.1| efflux membrane protein [Streptomyces griseoaurantiacus M045] gi|329305510|gb|EGG49366.1| efflux membrane protein [Streptomyces griseoaurantiacus M045] Length=484 Score = 247 bits (631), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 151/423 (36%), Positives = 245/423 (58%), Gaps = 9/423 (2%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 ++ R+R+ VLA + + +V +D ++NVALPS+Q+ T GLQWA+ Y+L +A++L Sbjct 4 LSHRRRMLVLAICCMSLLIVGLDNTVLNVALPSLQEDLDTSTSGLQWAIDAYTLVLASLL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GR+R F+ G+ +F S +C L +L V R++Q +G + ++ +++++ Sbjct 64 MLAGSTADRIGRKRVFLTGLAVFTAGSALCSLAPNLQTLVVFRMVQAVGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +PR +ARAI W A+ V A+ P +GGL+V+ +GWRS+F +N+P+G LLT Sbjct 124 ITNTFTDPRERARAIGAWGAVMGVSMAAGPLVGGLLVESVGWRSIFWLNIPVGLAALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGF--VAALLLAAGVL 237 L V ES+ P+P +LD +GQL +I + Y IIE P AGF V + A Sbjct 184 LRFVPESRAPKPRRLDPLGQLMVIALFGALTYAIIEVP-----DAGFRAVLPYAVLAAAA 238 Query 238 LWLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPL 297 L + +E R A PL+DL+ F + ++ + G L + T + QNVR L L Sbjct 239 LAGLLLYEPRRAEPLIDLRFFRSAPFSGATVIAISAFASLGGFLFLTTLYLQNVRGLDAL 298 Query 298 HAGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVAL- 356 HAGL MLP+ + + L+GR V GP+LP++ AM A+FA+ VAL Sbjct 299 HAGLWMLPMAVPTCLCAPLSGRLVGSRGPRLPLILAGCAMTACCALFAVFEAETSNVALF 358 Query 357 VGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWL 416 +G +FG G G +P+ + ++ + +AG+AA + + R LG GVA +G ++A+ + Sbjct 359 LGYVLFGIGFGFVNSPITNTAVSGMPKEQAGVAAAVASTSRQLGQTLGVAVVGAVLASGV 418 Query 417 GAA 419 GA+ Sbjct 419 GAS 421 >gi|29832191|ref|NP_826825.1| efflux membrane protein [Streptomyces avermitilis MA-4680] gi|29609309|dbj|BAC73360.1| putative efflux membrane protein [Streptomyces avermitilis MA-4680] Length=481 Score = 234 bits (598), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 157/424 (38%), Positives = 240/424 (57%), Gaps = 21/424 (4%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 ++PR+RL VLA L + +V +D ++NVALPS+QK H GLQW + Y+L +A++L Sbjct 4 LSPRRRLLVLAICCLSLLIVSLDNTVLNVALPSMQKELHASVAGLQWTIDAYTLVLASLL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GRRR F G+ LF + S++C L +L R++Q +G + ++ +++++ Sbjct 64 MLAGSTADRIGRRRVFRTGLVLFTIGSVLCSLAPNLESLVAFRMVQAVGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F PR +ARAI W + + A+ P +GGL+VD +GWRS+F +N+P+G + LLT Sbjct 124 ITNTFTEPRERARAIGVWGGVVGISMAAGPIVGGLLVDSVGWRSIFWINLPVGLVALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAG---- 235 V ES+ P+ + D VGQL +I + + Y IIEAP S+G AA +LA G Sbjct 184 WRYVPESRAPKARRPDPVGQLLVIALLGSLTYAIIEAP-----SSG--AAEILAFGGTAL 236 Query 236 ----VLLWLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNV 291 LLW +E R A PL+DL+ F + +V + G L + T + QNV Sbjct 237 AALIALLW----YEPRRAEPLIDLRFFRSVPFSGATVVAISAFAALSGFLFLSTLYLQNV 292 Query 292 RDLSPLHAGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHA 351 R LS LHAGL MLP+ V + L+GR V GP+ +LT AM +FA Sbjct 293 RGLSALHAGLWMLPMAVMCFVCAPLSGRLVGSRGPRFSLLTAGIAMTASGVLFAAFEAET 352 Query 352 HPVALV-GLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGT 410 V LV G +FG G G P+ + ++ + +AG+AA + + R +GG GVA +G Sbjct 353 SDVTLVIGYVLFGVGFGFVNAPITNTAVSGMPRAQAGVAAAIASTSRQIGGTLGVAVVGA 412 Query 411 IVAA 414 ++A+ Sbjct 413 VLAS 416 >gi|288918903|ref|ZP_06413246.1| drug resistance transporter, EmrB/QacA subfamily [Frankia sp. EUN1f] gi|288349655|gb|EFC83889.1| drug resistance transporter, EmrB/QacA subfamily [Frankia sp. EUN1f] Length=539 Score = 233 bits (593), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 142/411 (35%), Positives = 241/411 (59%), Gaps = 3/411 (0%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 +T +RL VL + + +V +D IVN+ALPS+++ F GLQW++ Y++ +A++L Sbjct 6 LTRNRRLAVLGICSMSLLIVGLDNTIVNIALPSLRRDFDASPAGLQWSIDSYTIVLASLL 65 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M +GDR GRRR F G+ LF + S++C + SL R++Q +G + ++ +++++ Sbjct 66 MLAGSMGDRLGRRRIFQTGLALFTLGSLLCSIAPSLHWLVAFRMVQAVGGSMLNPVAMSI 125 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +PR +ARAI W A+ + A P LGG++V+ +GWRS+F +N+P+G I L Sbjct 126 ITNTFTDPRERARAIGVWGAVIGISMALGPVLGGVLVEWVGWRSIFWINIPIGLIALTLA 185 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLW 239 + V ES+ P +LD VGQ+ +I +A + Y++I AP SA + LL AGV + Sbjct 186 QLYVPESRAARPRRLDAVGQVLVIFILAALTYSLIAAPEAGWTSARTL-GLLAGAGVAVA 244 Query 240 LFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHA 299 L VR+E R PL+D++LF + + + G+L++ T + Q+VR PLHA Sbjct 245 LLVRYESRREEPLLDVRLFRVASFSGATLTAVCALGALGGSLLLNTIYLQDVRGYEPLHA 304 Query 300 GLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIG-LAIFAISMDHAHPVALVG 358 GL+ LP+ AG + + L+GRAV ++GP+ +L + +G LA+ + L+ Sbjct 305 GLVTLPMAAGIIIGAPLSGRAVARFGPRPSLLAAGVGLTLGSLAMVGFDAGSSTGQLLIA 364 Query 359 LTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLG 409 +FGAG G P+ + ++ + +AG+AA + + R +G GVA +G Sbjct 365 YVVFGAGFGLVNAPITNTAVSGMPVEQAGVAAAVASTSRQVGQSLGVALVG 415 >gi|302560756|ref|ZP_07313098.1| drug resistance transporter, EmrB/QacA family protein [Streptomyces griseoflavus Tu4000] gi|302478374|gb|EFL41467.1| drug resistance transporter, EmrB/QacA family protein [Streptomyces griseoflavus Tu4000] Length=481 Score = 232 bits (591), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 142/417 (35%), Positives = 236/417 (57%), Gaps = 5/417 (1%) Query 5 QRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCA 63 +R+ VLA + + +V +D ++NVALPS+Q+ H GLQW + Y+L +A++LM Sbjct 8 RRMLVLAICCMSLLIVSLDNTVLNVALPSLQRDLHASTAGLQWTIDAYTLVLASLLMLAG 67 Query 64 LLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHS 123 DR GRRR F+ G+ +F + S++C L L V R++Q +G + ++ +++++++++ Sbjct 68 STADRIGRRRVFMTGLVVFTLGSVLCSLAPDLTSLVVFRMVQAVGGSMLNPVAMSIITNT 127 Query 124 FPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTLVGV 183 F +PR +ARAI W A+ + A+ P +GGL+V+ +GWR++F +N+P+G LLT V Sbjct 128 FTDPRERARAIGAWGAVVGISMAAGPLVGGLLVESVGWRAIFWINLPVGLAALLLTWRFV 187 Query 184 DESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWLFVR 243 ES+ P + D VGQL +I + Y IIEAP +A A + L +R Sbjct 188 PESRAPRARRPDPVGQLLVIVLFGSLTYAIIEAP---HAPLPVIAPFAAVALLALLALLR 244 Query 244 HEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGLMM 303 +E R PL+DL+ F + ++ + G L + T + QNVR LS + AGL M Sbjct 245 YEPRRREPLIDLRFFHSAPFSGATVIAVCAFAALGGFLFLSTLYLQNVRGLSAMEAGLWM 304 Query 304 LPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVAL-VGLTIF 362 LP+ + + L+GR V GP+LP+L AAM + +FA+ V L +G +F Sbjct 305 LPMAVPTFLCAPLSGRLVGSRGPRLPLLIAGAAMTVSGLLFALFEAETSDVTLFLGYVLF 364 Query 363 GAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAA 419 G G G P+ + ++ + +AG+A+ + + R LG GVA +G ++AA +G++ Sbjct 365 GVGFGFVNAPITNTAVSGMPTAQAGVASAVASTSRQLGQALGVAVIGAVLAAGVGSS 421 >gi|254382912|ref|ZP_04998268.1| efflux membrane protein [Streptomyces sp. Mg1] gi|194341813|gb|EDX22779.1| efflux membrane protein [Streptomyces sp. Mg1] Length=483 Score = 230 bits (586), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 142/420 (34%), Positives = 236/420 (57%), Gaps = 11/420 (2%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 ++ R+RL VLA + + +V +D ++NVALPS+++ H G+QW + Y+L +A++L Sbjct 4 LSHRRRLLVLAICCMSLLIVSLDNTVLNVALPSMRRELHASVAGMQWTIDAYTLVLASLL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 + DR GRR+ F G+T+FV+ S++C + SL V R +Q +G A ++ +++++ Sbjct 64 ILMGSTADRIGRRKVFTIGLTVFVLGSLLCSVAPSLGWLIVFRTVQAIGGAMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F P +ARAI W A+ + A+ P +GG++ D +GWRS+F +NVP+G LT Sbjct 124 ITNTFTEPAERARAIGIWGAVAGISMAAGPLIGGVLTDSVGWRSIFWINVPVGLFALALT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVL-- 237 L + ES+ P + D VGQL ++ + + Y IIE P +AG+ + L+L G + Sbjct 184 LRWIPESRAERPRRPDPVGQLLVMALLGSVTYGIIEGP-----AAGWSSGLILGCGAVAV 238 Query 238 --LWLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLS 295 L V +E R PL+D + F + ++ S G L + T + Q+VR L Sbjct 239 ASLVGLVAYEQRRTEPLIDPRFFRSVPFSGATVMAVSAFSGMAGFLFLNTLYLQDVRGLD 298 Query 296 PLHAGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFI-GLAIFAISMDHAHPV 354 L AGL MLP+ A +A+ +AGR V GP+LP+L AM + GL A S + + + Sbjct 299 ALDAGLYMLPMAACTILAAPVAGRLVAARGPRLPLLIAGVAMAVSGLLFAAFSAETSTSL 358 Query 355 ALVGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAA 414 G +FG G G P+ + ++ + +AG+AA + + R G GVA +G ++AA Sbjct 359 MFTGYVLFGLGFGMVNAPITNTAVSGMPRSQAGVAAAVASTSRQTGSTLGVAVIGAVLAA 418 >gi|294629228|ref|ZP_06707788.1| EmrB/QacA family drug resistance transporter [Streptomyces sp. e14] gi|292832561|gb|EFF90910.1| EmrB/QacA family drug resistance transporter [Streptomyces sp. e14] Length=483 Score = 230 bits (586), Expect = 6e-58, Method: Compositional matrix adjust. Identities = 145/421 (35%), Positives = 243/421 (58%), Gaps = 5/421 (1%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 ++ R+RL VLA + + +V +D ++NVALPS+Q+ H GLQW + Y+L +A++L Sbjct 4 LSHRRRLLVLAICCMSLLIVSIDNTVLNVALPSMQRELHASTSGLQWTIDAYTLVLASLL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GR+R F+ G+ +F V S++C L +L + V R++Q +G + ++ +++++ Sbjct 64 MLAGSTADRIGRKRIFMTGLIVFSVGSLLCSLAPNLELLIVFRMVQAVGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +PR +ARAI W A+ + A+ P +GGL+V+ +GWRS+F VN+P+G LLT Sbjct 124 ITNTFTDPRERARAIGVWGAVVGISMAAGPLVGGLLVESVGWRSIFWVNLPVGLAALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLW 239 L V ES+ P+ + D VGQ+ +I + Y IIEAP S V + A L Sbjct 184 LRFVPESRAPKARRPDPVGQVLVIALFGALTYAIIEAP---EASLARVVPFAVVALAALL 240 Query 240 LFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHA 299 + +E R PL+DL+ F + ++ + G L + T + QNVR L LHA Sbjct 241 GLLAYEPRRPEPLIDLRFFRSAPFSGATVIAVSAFAALGGFLFLSTLYLQNVRGLDALHA 300 Query 300 GLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIF-AISMDHAHPVALVG 358 GL MLP+ + + L+GR V GP+LP+L AAM + +F A + ++ ++G Sbjct 301 GLWMLPMALPTFLCAPLSGRLVGSRGPRLPLLVAGAAMTVSAVLFAAFEAETSNLTLVIG 360 Query 359 LTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGA 418 +FG G G P+ + ++ + +AG+AA + + R LG GVA +G ++A+ +G+ Sbjct 361 YVLFGIGFGFVNAPITNTAVSGMPRAQAGVAAAVASTSRQLGQTLGVAVVGALLASGIGS 420 Query 419 A 419 + Sbjct 421 S 421 >gi|291439775|ref|ZP_06579165.1| efflux protein [Streptomyces ghanaensis ATCC 14672] gi|291342670|gb|EFE69626.1| efflux protein [Streptomyces ghanaensis ATCC 14672] Length=470 Score = 228 bits (582), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 137/402 (35%), Positives = 229/402 (57%), Gaps = 5/402 (1%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 ++PR+R+ VLA + + +V +D ++NVALPS+Q+ FH GLQW++ Y+L +A++L Sbjct 7 LSPRRRVLVLAICCMSLLIVSLDNTVLNVALPSMQREFHASTSGLQWSIDAYTLVLASLL 66 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GR+R F+ G+ +F + S++C L SL V R++Q +G + ++ +++++ Sbjct 67 MLAGSTADRIGRKRVFMTGLVVFTLGSLLCSLAPSLEALVVFRMVQAVGGSMLNPVAMSI 126 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +PR +ARAI W A+ + A+ P +GGL+V +GWRS+F +N+P+G LLT Sbjct 127 ITNTFTDPRERARAIGAWGAVVGLSMAAGPLVGGLLVQSVGWRSIFWINLPVGLAALLLT 186 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLW 239 L V ES+ P + D VGQL +I + Y IIEAP + +A + A L Sbjct 187 LRFVPESRAPRARRPDPVGQLLVIALFGSLTYAIIEAPHATLPA---IAPFAVLALASLV 243 Query 240 LFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHA 299 + +E R PL+DL+ F + ++ + G L + T + QNVR LS L A Sbjct 244 ALLFYEPRRRDPLIDLRFFRSAPFSGATVIAVSAFAALGGFLFLTTLYLQNVRGLSALEA 303 Query 300 GLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAI-SMDHAHPVALVG 358 GL MLP+ + + L+GR V GP+LP+L AM + +FA+ + + +G Sbjct 304 GLWMLPMAVPTFLCAPLSGRLVGSRGPRLPLLIAGGAMTVSGLLFALFEAETSDATLFIG 363 Query 359 LTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLG 400 +FG G G P+ + ++ + +AG+A+ + + R LG Sbjct 364 YVLFGIGFGFVNAPITNTAVSGMPTAQAGVASAVASTSRQLG 405 >gi|337765578|emb|CCB74287.1| putative efflux membrane protein [Streptomyces cattleya NRRL 8057] Length=472 Score = 226 bits (577), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 147/412 (36%), Positives = 237/412 (58%), Gaps = 4/412 (0%) Query 14 LGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCALLGDRYGRRR 73 + + +V +D ++NVALPS+Q+ HT GLQW + Y+L +A++LM DR GRRR Sbjct 9 MSLLIVSLDNTVLNVALPSMQRELHTSVSGLQWTIDAYTLVLASLLMLSGSTADRIGRRR 68 Query 74 SFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHSFPNPRMKARA 133 +F G+ +F +S++C L SL+ AR++Q +G + ++ +++++++++F PR +ARA Sbjct 69 TFQVGLAVFSAASLLCSLAPSLSWLVAARMLQAVGGSMLNPVAMSIITNTFTVPRERARA 128 Query 134 ISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTLVGVDESQDPEPTQ 193 I W + + A+ P +GG +V+ GWR++F +NVP+G + +LT + V ES+ P+P + Sbjct 129 IGVWGGVVGISMAAGPIIGGALVESTGWRAIFWLNVPVGVLALVLTRLFVPESRAPKPRR 188 Query 194 LDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWLFVRHEHRAAFPLV 253 +D VGQL +I +A + Y IIE P S + LA LL + V +E R A PL+ Sbjct 189 VDPVGQLLMIVLLAALTYGIIETPAHGWSSPLVLGCEALAVLALLGI-VWYEPRRAEPLI 247 Query 254 DLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGLMMLPVPAGFGVA 313 DL+ F + ++ + G L + + + Q+VR L PLHAGL MLP+ A V Sbjct 248 DLRFFRSAPFSGATVIAICGFAALGGFLFLNSLYLQDVRGLDPLHAGLFMLPMAAMTLVC 307 Query 314 SLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVA-LVGL-TIFGAGAGGCAT 371 + L+GR V GP+LP+L AAM A+ P A LV + +FG G G Sbjct 308 APLSGRIVGARGPRLPLLLAGAAMCASAIPLAVDFSAHTPTAWLVAVYVVFGIGFGLVNA 367 Query 372 PLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVA-AWLGAALPN 422 P+ + ++ + +AG+AA + + R +G GVA +G ++A A LGA P Sbjct 368 PITNTAVSGMPRAQAGVAAAVASTSRQIGQSLGVAVIGAVMASASLGAGAPG 419 >gi|32141172|ref|NP_733574.1| efflux protein [Streptomyces coelicolor A3(2)] gi|289771764|ref|ZP_06531142.1| efflux protein [Streptomyces lividans TK24] gi|24413772|emb|CAD55309.1| putative efflux protein [Streptomyces coelicolor A3(2)] gi|289701963|gb|EFD69392.1| efflux protein [Streptomyces lividans TK24] Length=481 Score = 226 bits (576), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 140/404 (35%), Positives = 230/404 (57%), Gaps = 9/404 (2%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 +T R+R+ VLA + + +V +D I+NVALPS+Q+ H GLQWA+ Y+L +AA+L Sbjct 4 LTHRRRMLVLAICCMSLLIVSIDNTILNVALPSMQRDLHASTSGLQWAIDAYTLVLAALL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GR+R F+ G+ +F + S++C L L+ V R++Q +G + ++ +++++ Sbjct 64 MLSGSTADRIGRKRVFMTGLVIFTLGSLLCSLAPGLSSLIVFRMMQAVGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +PR +ARAI W A+ + A+ P +GG++V+ +GWRS+F VN+P+G LLT Sbjct 124 ITNTFTDPRERARAIGVWGAVVGISMAAGPLVGGVLVESVGWRSIFWVNLPVGLAALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGF--VAALLLAAGVL 237 L V ES+ P+ + D +GQL +I + Y IIEAP +AGF V + A Sbjct 184 LRFVPESRAPKARRPDPLGQLMVIVLFGSLTYAIIEAP-----NAGFRTVLPFAVLALAA 238 Query 238 LWLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPL 297 L + HE R PL++L+ F + ++ + G L + T + QNVR LS L Sbjct 239 LIGLLLHEPRRTDPLIELRFFRSAPFSGATVIAISAFAALGGFLFLSTLYLQNVRGLSAL 298 Query 298 HAGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIF-AISMDHAHPVAL 356 AGL MLP+ + + L+GR V GP+LP+L A+ + +F A + + Sbjct 299 EAGLWMLPMAVPTFLCAPLSGRLVGSRGPRLPLLIAGGALTVSGTLFAAFEAETSDLTLF 358 Query 357 VGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLG 400 +G +FG G G P+ + ++ + +AG+AA + + R LG Sbjct 359 LGYVLFGIGFGFVNAPITNTAVSGMPRSQAGVAAAVASTSRQLG 402 >gi|298246882|ref|ZP_06970687.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter racemifer DSM 44963] gi|297549541|gb|EFH83407.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter racemifer DSM 44963] Length=459 Score = 224 bits (572), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 145/421 (35%), Positives = 228/421 (55%), Gaps = 13/421 (3%) Query 3 PRQRLTVLATGL-----GIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAA 57 P ++ ++ A GL G FMV +D ++VNVALP++Q H +GLQW V GY+L A+ Sbjct 11 PSKKESIHALGLTAICFGFFMVILDTSVVNVALPAMQHDLHGSLEGLQWVVNGYTLIFAS 70 Query 58 VLMSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSL 117 +L+S LGDR G +R+F+ G LF +S++C L SL + AR++QG+G A + SL Sbjct 71 LLLSAGTLGDRLGHKRTFLTGYVLFTGASLLCSLAPSLNILIAARILQGVGPALLVPSSL 130 Query 118 ALLSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWL 177 +L++H F NP +ARA+ W +G A P +GGL+V+ LGWRS+FL+NVP G + Sbjct 131 SLITHGFQNPEKRARAVGFWAGSSGIGLAGGPIVGGLLVETLGWRSIFLLNVPFGLLALA 190 Query 178 LTLVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLL---AA 234 LT+ V E+ + D GQ +I A+A + Y +IE S V LL A+ Sbjct 191 LTMRFVSETPRTTTQKRDLWGQACVIVALATLTYALIEGRSQGWISLQIVGMFLLCIGAS 250 Query 235 GVLLWLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDL 294 G L + RH P++ L F+ + ++V V+ +G L V++ FQ++ Sbjct 251 GGFLLIETRHST----PMLPLHFFSSTAFSMPILVGCVLNFGLYGILFVLSLFFQDIYHY 306 Query 295 SPLHAGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPV 354 AG+ +LP+ G +L++GR + G + P++ LAA +G + + + Sbjct 307 PAALAGVALLPITVATGSTALISGRITARLGTRRPMIGGLAASCLGTLLLLLGETGDSIL 366 Query 355 AL-VGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVA 413 L VG + G G G + + V + G+A+ +LN R LGG+ GVA LG+I+ Sbjct 367 LLTVGEIVIGLGCGMTVPAMTTAILNTVPKSQVGVASALLNASRQLGGVLGVAILGSILG 426 Query 414 A 414 + Sbjct 427 S 427 >gi|121611491|ref|YP_999298.1| EmrB/QacA family drug resistance transporter [Verminephrobacter eiseniae EF01-2] gi|121556131|gb|ABM60280.1| drug resistance transporter, EmrB/QacA subfamily [Verminephrobacter eiseniae EF01-2] Length=452 Score = 224 bits (571), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 148/416 (36%), Positives = 222/416 (54%), Gaps = 12/416 (2%) Query 5 QRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCAL 64 QR + AT + +V +D +IVNVAL I HT GLQW V Y+L A +L+S Sbjct 8 QRRVLAATSISYIVVILDTSIVNVALERISNALHTHISGLQWVVNAYTLAFACLLLSGGT 67 Query 65 LGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHSF 124 LGDR+G R ++ G+ LF +S +C L + T+ARV+QG+GAA + SL L++H++ Sbjct 68 LGDRWGARNIYLAGLALFTAASALCGFAPDLTILTIARVLQGVGAALLVPCSLTLINHAY 127 Query 125 PNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAI-VWLLTLVGV 183 P+P +A A W + G A+ P +GGL+++ GWRS+FL NVP+G + VWL V Sbjct 128 PDPGERAVAFGVWASCGGAAMAAGPLVGGLLINMFGWRSIFLANVPIGLLGVWLTWRVAR 187 Query 184 DESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFV--AALLLAAGVLLWLF 241 D+S + + LD GQL+LI A+ + +IE P QS + A+ +A+G LF Sbjct 188 DKS-EAQIRHLDLSGQLSLIVALGSLITVLIEGPVLGWQSLPILIGIAVSIASGG---LF 243 Query 242 VRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGL 301 + E P++ L F L+ ++V V F+G + +++ +FQ VR+ S L GL Sbjct 244 LVIESLRDQPMLPLSFFGNGLFSGSVVVTMVSALIFYGLVFMLSLYFQQVRNYSALQTGL 303 Query 302 MMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCL---AAMFIGLAIFAISMDHAHPVALVG 358 LP+ A S+++ R K+GP+ PV L A F GL ++ D + + + Sbjct 304 SFLPLTAMVTFGSMISSRLTKKYGPRWPVAVALGLYATGFFGL--LPVTADSPYWMIALP 361 Query 359 LTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAA 414 L + G AG M V+ RAG+AAG+ N R G GVA G + A Sbjct 362 LPVIGLAAGLITPAATTALMGTVEKSRAGVAAGVQNSSRQTGASIGVAIFGALSVA 417 >gi|296136482|ref|YP_003643724.1| major facilitator superfamily MFS_1 [Thiomonas intermedia K12] gi|295796604|gb|ADG31394.1| major facilitator superfamily MFS_1 [Thiomonas intermedia K12] Length=472 Score = 223 bits (568), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 150/416 (37%), Positives = 234/416 (57%), Gaps = 14/416 (3%) Query 6 RLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCALL 65 R T++A LG +V +DV+ VNVAL ++ + F T GLQW V Y+L AA+L++ L Sbjct 19 RGTLIAAALGFVVVLLDVSAVNVALGALHRDFATAVAGLQWVVNAYTLVFAALLLTSGSL 78 Query 66 GDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHSFP 125 GDR G RR F+ G TLF ++S C + ++L + VAR+++GLGA+ + SLA+L +FP Sbjct 79 GDRLGSRRVFLCGFTLFTLASAACSVAINLPMLVVARLVEGLGASLLVPNSLAILKRAFP 138 Query 126 NPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL--VGV 183 + ++RA+ W AIG + A+ P LGGL+V GWRS+FL+N+P+G + LTL V Sbjct 139 DKLQRSRAVGWWGAIGGISLAAGPVLGGLLVTHWGWRSIFLINLPIGLVGGYLTLQYVAA 198 Query 184 DESQDPEPTQ--LDWVGQLTLIPAVALIAYTIIEAPRFDRQS----AGFVAALLLAAGVL 237 D S+ P LDW GQL I ++A + EA + S G + A++ AAG Sbjct 199 DGSRHPRHHDDGLDWPGQLVAILSLAAFTAALTEAGQLGWGSVWVQGGLLLAVVAAAG-- 256 Query 238 LWLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPL 297 F+ E R+ P++ L LF + I +V ++G + + + FQ + LSP Sbjct 257 ---FIWIESRSRSPMLPLGLFRVSAFTIATISGVIVNFSYYGLIFIFSLFFQIEQQLSPQ 313 Query 298 HAGLMMLPVPAGFGVASLLAGRAVNKWG-PQLPVLTCLAAMFIGLAIFAISMDHAHPVAL 356 G+ LP+ ++LAGR +++ G +L VL L A L + + +D A+ + Sbjct 314 QTGMAFLPMTIVLMGVNVLAGRLISRMGAKRLMVLGLLIAASGYLLLLPVRVDGAYGWLV 373 Query 357 VGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIV 412 V + I +G + ++ ++ VDD RAG+A+G+LN R +GG+ GVA G +V Sbjct 374 VPMLIASSGIALMVPTMTNVTLSSVDDSRAGIASGVLNSARQVGGLLGVAVFGYLV 429 >gi|256391255|ref|YP_003112819.1| drug resistance transporter EmrB/QacA subfamily [Catenulispora acidiphila DSM 44928] gi|256357481|gb|ACU70978.1| drug resistance transporter, EmrB/QacA subfamily [Catenulispora acidiphila DSM 44928] Length=480 Score = 222 bits (566), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 152/414 (37%), Positives = 228/414 (56%), Gaps = 14/414 (3%) Query 4 RQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCA 63 R +T+LAT L +F+ VD VN+ALP+I+ G GLQW V Y++ AA+L++ Sbjct 24 RPGVTLLATCLALFLGQVDTTAVNLALPAIRHDLSGGISGLQWVVDAYNVTFAALLLTGG 83 Query 64 LLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHS 123 LGDR+GRRR F GV +FV+ S VC L L V RV QG+G+ + SLA+L+ + Sbjct 84 TLGDRFGRRRLFRTGVAVFVLGSTVCALAPGLPVLLAGRVTQGVGSGMMLPQSLAILATA 143 Query 124 FPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTLVGV 183 FP R + +A++ W + G A P LGGL V LGW+S+F VNVP+G +LTL V Sbjct 144 FPGRRERNKAMAAWSIVAGSGLAVGPTLGGLAVQTLGWQSIFWVNVPIGIAALVLTLRHV 203 Query 184 DESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLW--LF 241 ES++P LD +GQ+ I ++ L+ + ++ S +A + AG ++ F Sbjct 204 PESRNPRARTLDPLGQVLAIASLGLLTFVAVQGRELGWTSPATLACI---AGCVVGPAAF 260 Query 242 VRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSC----FFGTLMVITQHFQNVRDLSPL 297 V E R + P++ L L L R L V +V +C +G ++ + FQ R S L Sbjct 261 VAVERRRSDPMLPLDL----LRRGQLPVAVIVAACMTFGMYGLFLLTSLMFQQERGASAL 316 Query 298 HAGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVAL- 356 AG+ MLP+ V S L GR V ++GP+LP+ + AM G+ IFA++ A+ + L Sbjct 317 GAGVAMLPLAVAATVLSPLTGRLVTRYGPRLPMTAGMTAMGTGVLIFAVAGADANLLVLE 376 Query 357 VGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGT 410 + T+ G G P++ + ++ V AG+A+G+ NL R G GVA G+ Sbjct 377 IAFTVIGIGLALNTGPVVGVAVSAVASELAGLASGIANLARMFGATLGVAVQGS 430 >gi|298251605|ref|ZP_06975408.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter racemifer DSM 44963] gi|297546197|gb|EFH80065.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter racemifer DSM 44963] Length=529 Score = 222 bits (565), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 144/444 (33%), Positives = 243/444 (55%), Gaps = 13/444 (2%) Query 4 RQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCA 63 R+ ++ T +G FMV +D +IVNVALP+IQ FH LQW V Y+L AA+L++ Sbjct 8 RKLAILIITCVGFFMVLLDTSIVNVALPTIQTDFHASLTDLQWMVDAYTLPFAALLLTAG 67 Query 64 LLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHS 123 LGDR+GR+R F+ G+ F + S +C L +L + R +QG G A +S SL+LL + Sbjct 68 SLGDRFGRKRLFLIGLIGFTLGSALCALAPNLQLLIAGRALQGAGGAALSPGSLSLLVAA 127 Query 124 FPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTLVGV 183 F + + + +A+ W I + A+ P +GG+++ W ++F VN+P+G +V++L + Sbjct 128 FTDHKERTQALGIWSGISGLALAAGPVVGGVLIRVSNWPAIFFVNLPIGTLVFILGWRIL 187 Query 184 DESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLL----AAGVLLW 239 ES++P +LD GQ+ I +A + Y +IE +SAG+ + L+L +A L Sbjct 188 AESRNPHARRLDLPGQVLAIAGLASLTYALIEG-----ESAGWTSPLILSLFASAAAFLI 242 Query 240 LFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHA 299 F+ E R PL+ L+LF ++ + VV T+ +TQ+FQ+V+ S L A Sbjct 243 AFLVVEARVREPLLPLQLFKSVVFSTANAAAAVVGFALLSTVFFVTQYFQSVQGYSALDA 302 Query 300 GLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALV-- 357 GL LP G + + +AG+ ++GP++P+ T A + + I +D A + Sbjct 303 GLRTLPSSMGIFLTAPVAGQVAARFGPRVPI-TLGALLSGVALLLLIRLDPTTSYANIWW 361 Query 358 GLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLG 417 ++G G G +PL G++ + RAG+ + +LN R +G +FG+A LG +V Sbjct 362 NQGMYGIGFGLMLSPLTAAGLSTIPQHRAGLGSAVLNTSRQIGSVFGIALLGALVEQQFI 421 Query 418 AALPNTMAD-EIPDPIARAIVVDV 440 L + +++ IP I++ +V + Sbjct 422 NNLFSKLSNLGIPGSISQKMVATI 445 >gi|297199530|ref|ZP_06916927.1| efflux protein [Streptomyces sviceus ATCC 29083] gi|297147422|gb|EDY56955.2| efflux protein [Streptomyces sviceus ATCC 29083] Length=481 Score = 220 bits (560), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 147/430 (35%), Positives = 242/430 (57%), Gaps = 23/430 (5%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 ++PR+R+ VLA + + +V +D +NVALP++Q+ GLQW + Y+L +A++L Sbjct 4 LSPRRRMLVLAICCMSLLIVSLDTTALNVALPAMQRGLDASTAGLQWTIDAYTLVLASLL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GR+R F+ G+ +F + S +C +L R++Q +G + ++ +++++ Sbjct 64 MLAGSTADRIGRKRVFMAGLIVFTIGSALCSAAPNLEALIAFRMVQAVGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +PR +ARAI W A+ + A+ P +GG++VD +GWRS+F VN+P+G LLT Sbjct 124 ITNTFTDPRERARAIGVWGAVVGISMAAGPLVGGVLVDSVGWRSIFWVNLPVGLAALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGF-------VAALLL 232 L V ES+ P + D VGQL +I + Y IIEAP ++GF V A+L Sbjct 184 LRYVPESRAPRARRPDPVGQLLVIALFGSLTYAIIEAP-----ASGFSYVLPFAVVAVLA 238 Query 233 AAGVLLWLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVR 292 AG LLW +E R PL+DL+ F + ++ + G L + T + QNVR Sbjct 239 LAG-LLW----YEPRRDEPLIDLRFFRSAPFSGATVIAISAFAGLGGFLFLSTLYLQNVR 293 Query 293 DLSPLHAGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFI---GLAIFAISMD 349 L LHAGL MLP+ + + LAGR V GP+LP++ A + I G+ A + Sbjct 294 GLDALHAGLWMLPMAVPMFLCAPLAGRLVGSRGPRLPLIA--AGVMITASGVLFAAFDAE 351 Query 350 HAHPVALVGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLG 409 + L+G +FG G G P+ + ++ + +AG+AA + + R LG GVA +G Sbjct 352 TSDRTLLLGYVLFGIGFGLVNAPITNTAVSGMPRAQAGVAAAVASTSRQLGQTLGVAVVG 411 Query 410 TIVAAWLGAA 419 ++A+ +G++ Sbjct 412 AVLASGVGSS 421 >gi|298251556|ref|ZP_06975359.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter racemifer DSM 44963] gi|297546148|gb|EFH80016.1| drug resistance transporter, EmrB/QacA subfamily [Ktedonobacter racemifer DSM 44963] Length=490 Score = 219 bits (559), Expect = 7e-55, Method: Compositional matrix adjust. Identities = 134/412 (33%), Positives = 232/412 (57%), Gaps = 2/412 (0%) Query 4 RQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCA 63 R+ L ++ + +F+V VD +I+NVALPSIQ FH QW + Y+L +A++L+ + Sbjct 21 RRNLILIICCVSVFLVGVDTSILNVALPSIQHDFHASIAEAQWTLDAYTLVIASLLVLSS 80 Query 64 LLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHS 123 DR GRRR F GV+LF + S++C L S+ V R++Q +G + ++ ++++++ ++ Sbjct 81 STADRVGRRRIFQLGVSLFTLGSLLCSLAPSITWLIVFRMMQAVGGSMLNPVAMSIIGNT 140 Query 124 FPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTLVGV 183 F P +ARA+ W + + A+ P LGGL+VD +GWRS+F +NVP G V LLT V Sbjct 141 FIKPAERARAVGVWGGVAGISLAAGPILGGLLVDSIGWRSIFWINVPFGIAVILLTAKFV 200 Query 184 DESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWLFVR 243 ES+ P P + D +GQ+ +I + L+ Y IIE P + S +A L+ AA + F+ Sbjct 201 PESKAPHPRRFDPIGQILVIALLGLLIYGIIEVPAYGWTSFEILACLIGAAACFVG-FIA 259 Query 244 HEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGLMM 303 +E PL+D++ F + I+ + G ++ T + Q++ SPL AG Sbjct 260 YERVRKEPLIDIRFFRSVPFSGASIIALCTFTALGGFSILNTLYLQDILHFSPLQAGTAF 319 Query 304 LPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVA-LVGLTIF 362 LP+ ++S ++GR + ++G ++ +L AA+ I + AI ++ + LV + Sbjct 320 LPMAVALAISSPISGRIIGRYGTRISLLIGGAAIAIAGLLAAIEYNNLPFIGLLVCYALV 379 Query 363 GAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAA 414 G+G G + + ++ + +AG AAG+ + R LG GVA +G+++A+ Sbjct 380 GSGVGWINAAISNTALSGMPRSQAGAAAGIASTMRQLGQALGVAVIGSVIAS 431 >gi|345015034|ref|YP_004817388.1| EmrB/QacA subfamily drug resistance transporter [Streptomyces violaceusniger Tu 4113] gi|344041383|gb|AEM87108.1| drug resistance transporter, EmrB/QacA subfamily [Streptomyces violaceusniger Tu 4113] Length=496 Score = 219 bits (559), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 134/411 (33%), Positives = 227/411 (56%), Gaps = 5/411 (1%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 ++ R+R+ VLA + + +V +D ++NVALPSI+ H G+QW + Y+L +AA+L Sbjct 4 LSHRRRMLVLAICCMSLLLVSLDNTVLNVALPSIRSDLHASVSGMQWTIDAYTLVLAALL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GR+R+F G+ +F + S +C L +L + R++Q +G + ++ +++++ Sbjct 64 MLSGSTADRVGRKRTFQTGLVIFTLGSGLCSLAPNLETLVIFRMVQAIGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 +++ F P+ +ARAI W + + A+ P +GG++V+ +GWRS+F +N+P+G LLT Sbjct 124 ITNVFTEPKERARAIGVWGGVVGISMAAGPIVGGVLVESVGWRSIFWINLPVGVAALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQ-SAGFVAALLLAAGVLL 238 V ES+ P+P + D VGQL ++ + + Y IIEAP DR + + A V L Sbjct 184 ARYVPESRAPKPRRADPVGQLLVVAVLGTLTYAIIEAP--DRGWDSPLIVTFAAIAAVGL 241 Query 239 WLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLH 298 +R+E R PL+DL+ F + +V + G L + T + Q+VR L LH Sbjct 242 IALIRYELRREEPLIDLRFFHSAPFSGATVVAVCAFAALSGYLFMNTLYLQDVRGLDALH 301 Query 299 AGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVA-LV 357 AGL MLP+ V + L+GR V GP+ +L A+ +FA+ + L+ Sbjct 302 AGLWMLPMAFMCFVCAPLSGRLVGARGPRPSMLVAGVAITASGVMFAVFDVQTTDIGLLL 361 Query 358 GLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFL 408 G +FG G G P+ + ++ + +AG+AA + + R +G GVA + Sbjct 362 GYAMFGLGFGMVNAPITNTAVSGMPRSQAGVAAAVASTSRQVGQSLGVAVI 412 >gi|297194492|ref|ZP_06911890.1| efflux membrane protein [Streptomyces pristinaespiralis ATCC 25486] gi|197718698|gb|EDY62606.1| efflux membrane protein [Streptomyces pristinaespiralis ATCC 25486] Length=490 Score = 219 bits (558), Expect = 9e-55, Method: Compositional matrix adjust. Identities = 145/425 (35%), Positives = 241/425 (57%), Gaps = 11/425 (2%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 ++ R R+ VLA + + +V +D I+NVALPS+++ G+QW + Y+L +A++L Sbjct 4 LSHRHRILVLAICCMSLLIVSLDNTILNVALPSLRRELDASVAGMQWVIDAYTLVLASLL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M + DR GRR+ F+ G+ LF + S++C L +L R++Q +G + ++ +++++ Sbjct 64 MLAGSVADRVGRRKIFMIGLVLFTLGSLLCSLAQNLGSLVAFRMVQAVGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +PR +ARAI W + + A+ P +GGL+VDG+GWRS+F VN+P+G LLT Sbjct 124 ITNTFTDPRERARAIGVWGGVVGISMAAGPLVGGLLVDGVGWRSIFWVNLPVGLAALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLA----AG 235 V ES+ P + D VGQL +I + + Y IIEAP AG+ + L+L A Sbjct 184 WRYVPESRAPRARRFDPVGQLLVITLLGSLTYAIIEAP-----VAGWTSPLILTFAVVAA 238 Query 236 VLLWLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLS 295 + L +RHE R A PL+DL+ F + ++ + G L V T + Q+VR LS Sbjct 239 LALAGLLRHEPRRAEPLIDLRFFHSLPFSGATVIAVSAFAALGGFLFVNTLYLQDVRGLS 298 Query 296 PLHAGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIF-AISMDHAHPV 354 L+AGL MLP+ V + L+GR V +GP+ +L AM +F A + + + Sbjct 299 ALNAGLYMLPMAGLTLVCAPLSGRLVAAYGPRPSLLAAGTAMTASGVLFAAFEAETSTAL 358 Query 355 ALVGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAA 414 G +FG G G P+ + ++ + +AG+AA + + R +G GVA +G ++AA Sbjct 359 LFTGYVLFGLGFGLVNAPITNTAVSGMPRAQAGVAAAVASTSRQIGQTLGVAVIGAVLAA 418 Query 415 WLGAA 419 + A+ Sbjct 419 GVSAS 423 >gi|229490123|ref|ZP_04383971.1| efflux membrane protein [Rhodococcus erythropolis SK121] gi|229322999|gb|EEN88772.1| efflux membrane protein [Rhodococcus erythropolis SK121] Length=467 Score = 218 bits (556), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 147/413 (36%), Positives = 231/413 (56%), Gaps = 7/413 (1%) Query 4 RQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSC 62 R+R +LA +F+V +D IVNVALP+I + F G +GL+W V Y+L +A++L+S Sbjct 17 RRRWGILAICCTSLFVVGLDTTIVNVALPTIGEGFRVGTRGLEWVVNAYTLVLASLLISS 76 Query 63 ALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSH 122 + DR+GRRR F G+ +F V+SI C L S+ V AR++QG+G + +S ++LA++ + Sbjct 77 GAVADRFGRRRVFQIGLVVFGVASIACALAPSVEVLIAARIVQGVGGSMLSPVALAIVVN 136 Query 123 SFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTLVG 182 +P+ +A+AI W A+ + A+ P +GG++++ GWRSVF +NVP+ V +LT V Sbjct 137 VMTDPKERAKAIGVWAAVFGLSMAAGPIVGGVLIESFGWRSVFWINVPVILAVLVLTAVF 196 Query 183 VDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWLFV 242 V ES+ + +LD GQL L+ V +IE PR SA A ++ A L F+ Sbjct 197 VPESRAQQSRRLDLPGQLLLVILVGGAVALLIEGPRIGWFSAAATAGYVVVAAALA-AFI 255 Query 243 RHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGLM 302 R E R PL+DL LF + S +I VV TL++ T + Q+ R +SP AG + Sbjct 256 RVESRKREPLMDLALFRRRPFSSAVIGAVVVFVALNATLLLGTFYLQHSRGMSPALAGAI 315 Query 303 MLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFI---GLAIFAISMDHAHPVALVGL 359 LP+ V + L+G V ++GP+ P+L +A F GL + ++ + A P+ L Sbjct 316 TLPMAVAATVCAPLSGILVGRFGPRRPLL--IAGSFTTLGGLCLVSLDNNTAIPMLLAAY 373 Query 360 TIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIV 412 G G G P+ + + + +AG+A G+ + R G GVA G I+ Sbjct 374 LFLGIGFGFSNAPITNTAVNGLPRSQAGLAGGITSSARQFGAALGVALAGGII 426 >gi|294812525|ref|ZP_06771168.1| Efflux membrane protein [Streptomyces clavuligerus ATCC 27064] gi|326441022|ref|ZP_08215756.1| efflux membrane protein [Streptomyces clavuligerus ATCC 27064] gi|294325124|gb|EFG06767.1| Efflux membrane protein [Streptomyces clavuligerus ATCC 27064] Length=482 Score = 217 bits (552), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 150/416 (37%), Positives = 237/416 (57%), Gaps = 12/416 (2%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 +T R+RL VLA + + +V +D I+NVALPSI + + GLQW + Y+L +A++L Sbjct 4 LTSRRRLLVLAICCMSLLIVSLDNTILNVALPSIGRELNASVTGLQWTIDAYTLVLASLL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GRRR FV G+ LF + S++C L SL V R++Q +G + ++ +++++ Sbjct 64 MLSGSTADRIGRRRVFVAGLALFTLGSLLCSLAPSLETLVVFRMVQAVGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +P +ARAI W + + A+ P +GGL+VD +GWRS+F VN+P+G LLT Sbjct 124 ITNTFTDPAERARAIGVWGGVVGISMAAGPLVGGLLVDTVGWRSIFWVNLPVGIAALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLW 239 L V ES+ P P + D VGQ+ +I + + Y IIE D AG A+L AGVL Sbjct 184 LRYVPESRAPRPRRPDPVGQVLIIALLGSLTYAIIET---DAVFAGI--AVLALAGVLY- 237 Query 240 LFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHA 299 +E R PL+DL+ F + ++ + G L + T + Q+VR + LHA Sbjct 238 ----YEPRRREPLIDLRFFRSAPFSGATVIAVCAFASLGGFLFLNTLYLQDVRGYTALHA 293 Query 300 GLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAM-FIGLAIFAISMDHAHPVALVG 358 GL MLP+ + S L+GR V GP+LP+L M G+ A + ++ + +G Sbjct 294 GLYMLPMAGLTLICSPLSGRLVGSRGPRLPLLIAGTTMGACGVLFAAFEAETSNALLFLG 353 Query 359 LTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAA 414 +FG G G TP+ + ++ + +AG+AA + + R +G GVA +GT++AA Sbjct 354 FALFGIGFGLVNTPITNTAVSGMPRAQAGVAAAVASTSRQIGQTLGVAVIGTVLAA 409 >gi|254389019|ref|ZP_05004249.1| efflux membrane protein [Streptomyces clavuligerus ATCC 27064] gi|197702736|gb|EDY48548.1| efflux membrane protein [Streptomyces clavuligerus ATCC 27064] Length=457 Score = 217 bits (552), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 150/416 (37%), Positives = 237/416 (57%), Gaps = 12/416 (2%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 +T R+RL VLA + + +V +D I+NVALPSI + + GLQW + Y+L +A++L Sbjct 4 LTSRRRLLVLAICCMSLLIVSLDNTILNVALPSIGRELNASVTGLQWTIDAYTLVLASLL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GRRR FV G+ LF + S++C L SL V R++Q +G + ++ +++++ Sbjct 64 MLSGSTADRIGRRRVFVAGLALFTLGSLLCSLAPSLETLVVFRMVQAVGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +P +ARAI W + + A+ P +GGL+VD +GWRS+F VN+P+G LLT Sbjct 124 ITNTFTDPAERARAIGVWGGVVGISMAAGPLVGGLLVDTVGWRSIFWVNLPVGIAALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLW 239 L V ES+ P P + D VGQ+ +I + + Y IIE D AG A+L AGVL Sbjct 184 LRYVPESRAPRPRRPDPVGQVLIIALLGSLTYAIIET---DAVFAGI--AVLALAGVLY- 237 Query 240 LFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHA 299 +E R PL+DL+ F + ++ + G L + T + Q+VR + LHA Sbjct 238 ----YEPRRREPLIDLRFFRSAPFSGATVIAVCAFASLGGFLFLNTLYLQDVRGYTALHA 293 Query 300 GLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAM-FIGLAIFAISMDHAHPVALVG 358 GL MLP+ + S L+GR V GP+LP+L M G+ A + ++ + +G Sbjct 294 GLYMLPMAGLTLICSPLSGRLVGSRGPRLPLLIAGTTMGACGVLFAAFEAETSNALLFLG 353 Query 359 LTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAA 414 +FG G G TP+ + ++ + +AG+AA + + R +G GVA +GT++AA Sbjct 354 FALFGIGFGLVNTPITNTAVSGMPRAQAGVAAAVASTSRQIGQTLGVAVIGTVLAA 409 >gi|338778012|gb|EGP42499.1| drug resistance MFS transporter, drug:H+ antiporter 1 [Achromobacter xylosoxidans AXX-A] Length=497 Score = 216 bits (550), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 147/417 (36%), Positives = 222/417 (54%), Gaps = 7/417 (1%) Query 1 MTP-RQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 MTP R+R V A LG F+ +D++IVNVALP++Q GLQW V Y+L ++A + Sbjct 1 MTPNRRRALVFAVNLGSFITILDISIVNVALPTMQAALRIDMAGLQWVVDAYALFLSAFM 60 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 +S LGDRYGR+RS++ GV LF + S C + +L + R +QG+ A + +++L Sbjct 61 LSAGPLGDRYGRKRSWLAGVALFTLGSAFCGMADNLPLLLAGRAVQGVAGALLIPGAMSL 120 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 L+ +FP+P +ARAI W + + P LGGL+V W+S+FL+N+P+G + L Sbjct 121 LTQAFPDPGERARAIGLWASCNAISLIVGPMLGGLLVAHFSWQSIFLINLPVGVVAIALG 180 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLW 239 G+ ES PE D GQ + + + Y +I A Q+ G +AAL +AA + L Sbjct 181 AWGIQESAHPEHAAFDPAGQALSVIWLGALTYGLIAAGEHGWQAPGTLAALAVAA-IGLT 239 Query 240 LFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHA 299 F+ EH A P++ L LF + + S FV+ + +L + + Q+VR LSPL A Sbjct 240 AFLWVEHTVARPILPLGLFRDAGFASTNFASFVMGFGAYSSLFFFSLYLQHVRGLSPLEA 299 Query 300 GLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFA-ISMDHAHPVALVG 358 G + P G+ S + GR ++G LP L +G A+ +S D P AL G Sbjct 300 GWQLAPQFVATGIVSTVFGRLNLRFG--LPRLMIAGYGMVGAAMLGMMSFDAHTPYALSG 357 Query 359 LTIFGAGAG-GCATPLLHLG-MTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVA 413 + G G G A P + M V R+GMA+ +N R G G+A LG +++ Sbjct 358 SLMVLLGLGMGLAVPATSMAVMATVPRERSGMASATMNALRQTGMTIGIALLGALMS 414 >gi|158318319|ref|YP_001510827.1| EmrB/QacA family drug resistance transporter [Frankia sp. EAN1pec] gi|158113724|gb|ABW15921.1| drug resistance transporter, EmrB/QacA subfamily [Frankia sp. EAN1pec] Length=502 Score = 214 bits (545), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 142/415 (35%), Positives = 232/415 (56%), Gaps = 11/415 (2%) Query 2 TPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 T R+R VLA + + +V +D IVNVALP++++ GLQW + Y+L +A++LM Sbjct 5 TSRRRFAVLAICCMSLLIVGLDGTIVNVALPALRRDLGASPAGLQWTIDSYTLVLASLLM 64 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 GDR GRRR F G+ LF S++C L L V R++Q +G + ++ ++++++ Sbjct 65 LGGSTGDRLGRRRIFQTGLALFTAGSLLCSLAPGLGWLVVFRMVQAVGGSMLNPVAMSII 124 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 +++F +PR +ARAI W A+ + A P LGG++V+ + WR++F +N+P+G +LT Sbjct 125 TNTFTDPRERARAIGLWGAVIGISMALGPVLGGILVETVSWRAIFWINIPIGLAALVLTH 184 Query 181 VGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAA----LLLAAGV 236 V ES+ P P +LD VGQL +I +A + Y+IIEAP +AG+ +A LL A Sbjct 185 RFVPESRAPSPRRLDPVGQLLVIAVLATLTYSIIEAP-----AAGWTSAETLVLLAVAVA 239 Query 237 LLWLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSP 296 L V +E R PL+D++ F + + G L + T + Q+VR S Sbjct 240 AAALLVGYESRRTEPLLDVRFFRSAPFSGATAIAVCAFGALAGFLFLNTIYLQDVRGYSA 299 Query 297 LHAGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIG-LAIFAISMDHAHPVA 355 LHAGL+ LP+ V + L+GRAV ++GP+ +L A+ G A+ +S + Sbjct 300 LHAGLLTLPMALATLVIAPLSGRAVGRFGPRPSLLAAGVALTAGSAAMTGLSPQTSVTTL 359 Query 356 LVGLTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGT 410 +V +FG G G P+ + ++ + +AG+AA + + R +G GVA +G+ Sbjct 360 MVAYVLFGTGFGLVNAPITNTAVSGMPLEQAGVAAAVASTSRQVGQSLGVAVIGS 414 >gi|157371058|ref|YP_001479047.1| major facilitator transporter [Serratia proteamaculans 568] gi|157322822|gb|ABV41919.1| major facilitator superfamily MFS_1 [Serratia proteamaculans 568] Length=463 Score = 214 bits (545), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 148/420 (36%), Positives = 225/420 (54%), Gaps = 14/420 (3%) Query 1 MTPRQRLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLM 60 + Q+ ++AT L +V +D +IVNVALPSI G GLQW V Y+L A++L+ Sbjct 4 LNQHQKSVLMATSLSYVIVILDTSIVNVALPSIAGELGAGLSGLQWVVNAYTLAFASLLL 63 Query 61 SCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALL 120 S LGDR G R ++ G+ +F +S++C L +L V ARV QG+GAA + SL LL Sbjct 64 SGGALGDRLGATRLYLGGLAVFAGASVICGLAETLPVLVAARVCQGVGAALLVPSSLMLL 123 Query 121 SHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTL 180 + +F + R++A AI W G V A+ P +GGL+++ GWRS+F +N+P+ IV + L Sbjct 124 NAAFGDARLRAGAIGVWAGCGGVAMAAGPLVGGLLIELWGWRSLFWINLPV--IVLGIGL 181 Query 181 VGVDESQDPEPT--QLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLL 238 E + P P Q+D+ GQ +I A+A + +IE R S + + +AA + Sbjct 182 TLRIEVRRPVPALRQMDYAGQGAVILALASSVWVLIEGTRLGWCSGWILGGMAIAA-LSW 240 Query 239 WLFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLH 298 W FV E R P++ L LF L+ + +V V F+G +++ +FQ VR +PL Sbjct 241 WRFVVIERRHRQPMLPLTLFRSTLFSASALVSLVSALVFYGVFFLLSLYFQRVRGWTPLQ 300 Query 299 AGLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCL---AAMFIGLAIFAISMDHAHPVA 355 +GL LP+ + S ++GR V WG V L A F+GL +++ + P Sbjct 301 SGLAFLPLTMMVTLGSFISGRLVRAWGGGRVVYCSLLLYALGFVGL----LALAESPPYW 356 Query 356 LVGLT--IFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVA 413 + L+ + G AG M V + RAG+AAG+LN R G FGVA G +++ Sbjct 357 RIALSFPLLGLAAGIITPAATSALMNDVANERAGIAAGVLNAARQSGSAFGVAIFGALMS 416 >gi|302534307|ref|ZP_07286649.1| efflux protein [Streptomyces sp. C] gi|302443202|gb|EFL15018.1| efflux protein [Streptomyces sp. C] Length=504 Score = 213 bits (543), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 144/416 (35%), Positives = 235/416 (57%), Gaps = 3/416 (0%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 M+ R+RL VLA + + +V +D ++NVALP++++ FH G+QW + Y+L +A++L Sbjct 1 MSRRRRLLVLAICCMSLLIVSLDNTVLNVALPAMRREFHASVSGMQWTIDAYTLVIASLL 60 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 + DR GRRR F +G+ LF S++C L L R++Q +G A ++ +++++ Sbjct 61 ILAGSTADRIGRRRVFAWGLVLFTAGSVLCSLAPGLEWLIAFRMLQAVGGAMLNPVAMSI 120 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +PR +ARAI W A+ + A+ P +GGL+VD +GWRS+F VNVP+G + LLT Sbjct 121 ITNTFTDPRERARAIGVWGAVVGISMAAGPLVGGLLVDSVGWRSIFWVNVPVGLLALLLT 180 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLW 239 L V ES+ P + D VGQL ++ + + Y IIEAP + S+ + L A L Sbjct 181 LRHVPESRSERPRRADPVGQLLVMVLLGGVTYAIIEAPA-EGWSSPPILGCALGAAAALA 239 Query 240 LFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHA 299 + +E R A PL+D + F + ++ + G L + T + Q VR L L A Sbjct 240 GLLYYESRRADPLIDPRFFRSAPFSGATVIAVSTFASLSGFLFLTTLYLQEVRGLGALDA 299 Query 300 GLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAM-FIGLAIFAISMDHAHPVALVG 358 GL MLP+ A + + ++GR V +GP+ +L AM GL A S + + P+ G Sbjct 300 GLHMLPMAAFAFLCAPVSGRLVANYGPRPSLLIAGVAMGASGLLFAAFSAETSTPLMFTG 359 Query 359 LTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAA 414 +FG G G P+ + ++ + +AG+AA + + R GG GVA +G ++AA Sbjct 360 YVLFGIGFGLVNAPITNTAVSGMPRAQAGVAAAVASTSRQTGGALGVAVIGAVLAA 415 >gi|226304701|ref|YP_002764659.1| drug resistance efflux protein [Rhodococcus erythropolis PR4] gi|226183816|dbj|BAH31920.1| putative drug resistance efflux protein [Rhodococcus erythropolis PR4] Length=472 Score = 212 bits (540), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 145/414 (36%), Positives = 236/414 (58%), Gaps = 7/414 (1%) Query 4 RQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSC 62 R+R +LA +F+V +D IVNVALP+I + F G GL+W V Y+L +A++L+S Sbjct 22 RRRWGILAICCTSLFVVGLDTTIVNVALPAIGEGFGVGTVGLEWIVNAYTLVLASLLISS 81 Query 63 ALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSH 122 L DR+GRRR F G+ +F V+SIVC L S+ V AR+ QG+G + +S ++LA++ + Sbjct 82 GALADRFGRRRIFQIGLVVFGVASIVCALAPSVGVLIAARIAQGVGGSMLSPVALAIVVN 141 Query 123 SFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTLVG 182 +P+ +A+AI W A+ + A+ P +GG++++ GWRSVF +NVP+ A+V +LT V Sbjct 142 VMTDPKERAKAIGVWAAVFGLSMAAGPIVGGVLIESFGWRSVFWINVPVIAVVLMLTAVF 201 Query 183 VDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWLFV 242 V +S+ +P +LD GQ+ L+ V +IE PR ++G +A + A L FV Sbjct 202 VPQSRAEQPRRLDLPGQVLLMVVVGGSVALLIEGPRIGWLASGAIAGYVAVAAALA-AFV 260 Query 243 RHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGLM 302 R E R + PL+D LF + + ++ VV TL++ T + Q R+++P AG M Sbjct 261 RVESRKSEPLMDPSLFRHRPFTAAVLGAIVVFVALNATLLLGTFYLQQAREMTPAAAGAM 320 Query 303 MLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGL-AIFAISMDHAHPVA--LVGL 359 LP+ + + L+G V ++G +LP+L +A F L + +S+D++ + LV Sbjct 321 TLPMAVAATICAPLSGILVGRFGARLPLL--IAGSFTALGGLCLVSLDNSTGTSTLLVAY 378 Query 360 TIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVA 413 G G G P+ + + + +AG+A G+ + R G GVA G ++A Sbjct 379 LFLGIGFGFSNAPITNTAVNGLPRSQAGLAGGITSSARQFGAALGVALAGGMIA 432 >gi|107027637|ref|YP_625148.1| major facilitator transporter [Burkholderia cenocepacia AU 1054] gi|116693652|ref|YP_839185.1| major facilitator transporter [Burkholderia cenocepacia HI2424] gi|105897011|gb|ABF80175.1| major facilitator superfamily MFS_1 [Burkholderia cenocepacia AU 1054] gi|116651652|gb|ABK12292.1| major facilitator superfamily MFS_1 [Burkholderia cenocepacia HI2424] Length=468 Score = 211 bits (537), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 147/414 (36%), Positives = 214/414 (52%), Gaps = 13/414 (3%) Query 6 RLTVLATGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCALL 65 R + AT + +V +D +IVNVAL I F + GLQW V Y+L A++L++ L Sbjct 12 RRVLAATCVSYMLVLLDASIVNVALTDIAHTFGSRVAGLQWIVNAYTLAFASLLLTGGTL 71 Query 66 GDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHSFP 125 GDR G R +V G+ +FV +S +C + +L VAR +QG+G+A + SLAL++ +FP Sbjct 72 GDRLGDRTVYVAGLAVFVAASALCGVAPTLPALAVARALQGVGSAMLVPCSLALINRAFP 131 Query 126 NPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLG-AIVWLLTLV--- 181 P +A AIS WM G + AS P +GGL++D GWRS+F VN+PLG A +WL V Sbjct 132 EPAARASAISVWMGCGGIAMASGPLIGGLLIDLSGWRSLFFVNLPLGLAGIWLGRTVAPA 191 Query 182 GVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLWL- 240 VD S+ Q DW GQ I A+ + T+IE P +SA V + A V+ W+ Sbjct 192 AVDRSR-----QFDWGGQAAAIVAIGALIGTLIEGPSLGWRSAPIVGGAM--ASVVAWIA 244 Query 241 FVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAG 300 F+ E R P++ L F L+ V F+G L V++ ++ VR SPL G Sbjct 245 FIAIEARRRAPMLPLAFFRNRLFAGSTFVSMASAFVFYGLLFVLSLFYRQVRGASPLDTG 304 Query 301 LMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIG-LAIFAISMDHAHPVALVGL 359 L LP+ A + L +GR V ++G + + G L I AI +A+ + Sbjct 305 LAFLPMTAMVALGGLTSGRVVARFGARGTMCAAFGLYAAGALGITAIGATTPAWLAVAPM 364 Query 360 TIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVA 413 G +G + + +D RAG+AA +LN R G GVA G +A Sbjct 365 LAIGFASGFISPAATAPALGTIDRPRAGVAAAVLNAARQSGSALGVAIFGACIA 418 >gi|296117263|ref|ZP_06835855.1| drug resistance transporter, EmrB/QacA subfamily protein [Gluconacetobacter hansenii ATCC 23769] gi|295976216|gb|EFG83002.1| drug resistance transporter, EmrB/QacA subfamily protein [Gluconacetobacter hansenii ATCC 23769] Length=506 Score = 211 bits (536), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 141/413 (35%), Positives = 227/413 (55%), Gaps = 14/413 (3%) Query 14 LGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVLMSCALLGDRYGRRR 73 L + +V +DV IVNVALPSI+ H LQW V GY+L +A++L+ + DR GRRR Sbjct 36 LSLLLVMMDVTIVNVALPSIRTALHGSFSTLQWVVDGYTLMVASLLVLMGAIADRLGRRR 95 Query 74 SFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLALLSHSFPNPRMKARA 133 FV G+++F + S++C L S+ + AR++QG+G A ++ ++L+++++ F PR +A+A Sbjct 96 VFVAGISVFCLGSMLCALSGSITMLVGARMLQGIGGAMLNPVALSIIANVFTEPRARAQA 155 Query 134 ISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLTLVGVDESQDPEPTQ 193 I W V A P +GG++V + W++VF VNVP+GA+ L+L + ES+ P Sbjct 156 IGVWGGASGVALALGPVVGGVLVHWVNWQAVFWVNVPIGAMAIFLSLRFIPESRAPHIRP 215 Query 194 LDWVGQLTLIPAVALIAYTIIEAPRF---DRQSAGFVAALLLAAGVLLWL-FVRHEHRAA 249 D GQL ++ +A++ +IE F D +GF L+ GVL + FV E R+ Sbjct 216 FDAPGQLLVMVTLAMLTAALIEVRDFGWGDPVISGF-----LSLGVLAMVGFVIVEQRST 270 Query 250 FPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHAGLMMLPVPAG 309 PLVDL+ F + ++ + + F L + T + Q R +S LHAGL LP Sbjct 271 APLVDLRFFHALPFSGAIVTAILAFAVFSAFLFLNTLYLQGARAMSALHAGLCTLPFAVC 330 Query 310 FGVASLLAGRAVNKWGPQLPVLTCLAAM-FIGLAIFAISMDHAHP--VALVGLTIFGAGA 366 + + L+GR V + G ++P+L L+A+ F A+ + A P V L + G G Sbjct 331 SSICAPLSGRLVGRIGARVPLL--LSALGFAVSALLLTQLSAATPLGVLLAAYGLCGCGF 388 Query 367 GGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGAA 419 G C P+ + + + +AG+AA + + R +G + G+A GT+ G A Sbjct 389 GLCNAPITNAAVAGMPRSQAGVAAALASTSRQIGVLLGIALCGTLTGGAAGQA 441 >gi|290960586|ref|YP_003491768.1| major facilitator transporter [Streptomyces scabiei 87.22] gi|260650112|emb|CBG73228.1| putative major facilitator transporter [Streptomyces scabiei 87.22] Length=481 Score = 210 bits (534), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 150/421 (36%), Positives = 238/421 (57%), Gaps = 5/421 (1%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 ++ R RL VLA + +V +D ++NVALPS+Q+ GLQW + Y+L +AA+L Sbjct 4 LSRRHRLLVLAICCTSLLIVSLDNTVLNVALPSMQRDLDASLAGLQWTIDAYTLVLAALL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GRRR F+ G+ +F S++C L +L V R++Q +G + ++ +++++ Sbjct 64 MLAGSTADRIGRRRVFMAGLVVFAAGSLLCSLAPNLESLVVFRMVQAVGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +PR +ARAI W A+ + A+ P +GGL+V+ +GWRS+F +N+P+G LLT Sbjct 124 ITNTFTDPRERARAIGAWGAVVGISMAAGPIIGGLLVESVGWRSIFWINLPVGLAALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLW 239 V ES+ P+ + D VGQL +I + + Y IIEAP + A+ LAA + L Sbjct 184 WRFVPESRAPKARRPDPVGQLLVIALLGSLTYAIIEAPTAPLPRTLALGAVALAALLGL- 242 Query 240 LFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHA 299 +R+E R PL+DL+ F + ++ + G L + T + QNVR L LHA Sbjct 243 --LRYEPRREEPLIDLRFFRSAPFSGATVIAVSAFAGLGGFLFLSTLYLQNVRGLDALHA 300 Query 300 GLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFIGLAIFAISMDHAHPVALV-G 358 GL MLP+ V + +AGR V GP+LP+L AM +FA V LV G Sbjct 301 GLWMLPMAVLCFVCAPVAGRLVGSRGPRLPLLIAGIAMTASGVLFAAFEAETGNVTLVIG 360 Query 359 LTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLGGIFGVAFLGTIVAAWLGA 418 +FG G G P+ + ++ + +AG+AA + + R +G GVA +G ++AA +GA Sbjct 361 YVLFGLGFGFVNAPITNTAVSGMPRAQAGVAAAVASTSRQIGQTLGVAVIGAVLAAGIGA 420 Query 419 A 419 + Sbjct 421 S 421 >gi|302551271|ref|ZP_07303613.1| efflux protein [Streptomyces viridochromogenes DSM 40736] gi|302468889|gb|EFL31982.1| efflux protein [Streptomyces viridochromogenes DSM 40736] Length=481 Score = 209 bits (533), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 137/402 (35%), Positives = 226/402 (57%), Gaps = 5/402 (1%) Query 1 MTPRQRLTVLA-TGLGIFMVFVDVNIVNVALPSIQKVFHTGEQGLQWAVAGYSLGMAAVL 59 ++ R+R+ VLA + + +V +D ++NVALPS+Q+ H GLQW + Y+L +A++L Sbjct 4 LSHRRRMLVLAICCMSLLIVSLDNTVLNVALPSMQQDLHASTSGLQWTIDAYTLVLASLL 63 Query 60 MSCALLGDRYGRRRSFVFGVTLFVVSSIVCVLPVSLAVFTVARVIQGLGAAFISVLSLAL 119 M DR GR+R F+ G+ +F + S++C L +L R++Q +G + ++ +++++ Sbjct 64 MLAGSTADRIGRKRVFMAGLVVFTLGSVLCSLAPNLEALIAFRMVQAVGGSMLNPVAMSI 123 Query 120 LSHSFPNPRMKARAISNWMAIGMVGAASAPALGGLMVDGLGWRSVFLVNVPLGAIVWLLT 179 ++++F +PR +ARAI W A+ + A+ P +GGL+V+ +GWRS+F +N+P+G LLT Sbjct 124 ITNTFTDPRERARAIGVWGAVVGISMAAGPLVGGLLVESVGWRSIFWINLPVGLAALLLT 183 Query 180 LVGVDESQDPEPTQLDWVGQLTLIPAVALIAYTIIEAPRFDRQSAGFVAALLLAAGVLLW 239 L V ES+ + D VGQL +I + Y IIEAP S A L++ A L Sbjct 184 LRFVPESRAGRARRPDPVGQLLVIALFGSLTYAIIEAPTTPFAS---TAPLVVVALAALT 240 Query 240 LFVRHEHRAAFPLVDLKLFAEPLYRSVLIVYFVVMSCFFGTLMVITQHFQNVRDLSPLHA 299 + +E R A PL+DL+ F + ++ + G L + T + QNVR L+ L A Sbjct 241 GLLLYEPRRAEPLIDLRFFRSAPFSGATVIAISAFAALGGFLFLSTLYLQNVRGLTALEA 300 Query 300 GLMMLPVPAGFGVASLLAGRAVNKWGPQLPVLTCLAAMFI-GLAIFAISMDHAHPVALVG 358 GL MLP+ A + + L+GR V GP+LP+L AM GL A + + + G Sbjct 301 GLWMLPMAAPTFLCAPLSGRLVGTRGPRLPLLIAGGAMTASGLLFAAFDAETSDLTLVAG 360 Query 359 LTIFGAGAGGCATPLLHLGMTKVDDGRAGMAAGMLNLQRSLG 400 +FG G G P+ + ++ + +AG+AA + + R LG Sbjct 361 YVLFGIGFGFVNAPITNTAVSGMPRAQAGVAAAVASTSRQLG 402 Lambda K H 0.328 0.141 0.432 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1101757964944 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40