BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2497c Length=367 Score E Sequences producing significant alignments: (Bits) Value gi|15609634|ref|NP_217013.1| pyruvate dehydrogenase E1 component... 754 0.0 gi|289448142|ref|ZP_06437886.1| pyruvate dehydrogenase E1 compon... 753 0.0 gi|289746279|ref|ZP_06505657.1| pyruvate dehydrogenase E1 compon... 752 0.0 gi|308232154|ref|ZP_07415107.2| pyruvate dehydrogenase E1 compon... 733 0.0 gi|323718905|gb|EGB28059.1| pyruvate dehydrogenase E1 component ... 729 0.0 gi|289754606|ref|ZP_06513984.1| pyruvate dehydrogenase E1 compon... 709 0.0 gi|289570657|ref|ZP_06450884.1| pyruvate dehydrogenase E1 compon... 669 0.0 gi|240171578|ref|ZP_04750237.1| putative pyruvate dehydrogenase ... 627 8e-178 gi|296170433|ref|ZP_06852021.1| pyruvate dehydrogenase complex E... 615 5e-174 gi|342857888|ref|ZP_08714544.1| PdhA [Mycobacterium colombiense ... 612 3e-173 gi|183983819|ref|YP_001852110.1| pyruvate dehydrogenase E1 compo... 606 2e-171 gi|254823116|ref|ZP_05228117.1| PdhA [Mycobacterium intracellula... 603 1e-170 gi|118619020|ref|YP_907352.1| pyruvate dehydrogenase E1 componen... 597 1e-168 gi|118466239|ref|YP_880907.1| pyruvate dehydrogenase E1 componen... 595 3e-168 gi|254774501|ref|ZP_05216017.1| PdhA [Mycobacterium avium subsp.... 595 4e-168 gi|41408407|ref|NP_961243.1| PdhA [Mycobacterium avium subsp. pa... 593 1e-167 gi|289762665|ref|ZP_06522043.1| pyruvate dehydrogenase E1 compon... 583 2e-164 gi|333990058|ref|YP_004522672.1| pyruvate dehydrogenase E1 compo... 582 5e-164 gi|108800592|ref|YP_640789.1| pyruvate dehydrogenase (lipoamide)... 557 1e-156 gi|120405040|ref|YP_954869.1| pyruvate dehydrogenase [Mycobacter... 547 9e-154 gi|118467989|ref|YP_888972.1| pyruvate dehydrogenase E1 componen... 542 4e-152 gi|289751106|ref|ZP_06510484.1| pyruvate dehydrogenase E1 compon... 527 1e-147 gi|289444027|ref|ZP_06433771.1| pyruvate dehydrogenase E1 compon... 468 8e-130 gi|238059377|ref|ZP_04604086.1| pyruvate dehydrogenase [Micromon... 322 7e-86 gi|308178212|ref|YP_003917618.1| 2-oxoacid dehydrogenase E1 comp... 322 9e-86 gi|315505682|ref|YP_004084569.1| pyruvate dehydrogenase e1 compo... 321 1e-85 gi|302867913|ref|YP_003836550.1| pyruvate dehydrogenase E1 compo... 320 3e-85 gi|145594629|ref|YP_001158926.1| pyruvate dehydrogenase [Salinis... 319 4e-85 gi|330468696|ref|YP_004406439.1| pyruvate dehydrogenase e1 compo... 317 1e-84 gi|159037836|ref|YP_001537089.1| pyruvate dehydrogenase [Salinis... 314 2e-83 gi|289706157|ref|ZP_06502524.1| dehydrogenase E1 component [Micr... 313 3e-83 gi|239918260|ref|YP_002957818.1| pyruvate/2-oxoglutarate dehydro... 312 5e-83 gi|290963053|ref|YP_003494235.1| pyruvate dehydrogenase E1 prote... 312 7e-83 gi|163839304|ref|YP_001623709.1| pyruvate dehydrogenase E1 compo... 312 7e-83 gi|331696888|ref|YP_004333127.1| pyruvate dehydrogenase [Pseudon... 311 1e-82 gi|302529578|ref|ZP_07281920.1| pyruvate dehydrogenase E1 compon... 310 2e-82 gi|295695284|ref|YP_003588522.1| pyruvate dehydrogenase E1 compo... 310 2e-82 gi|325964391|ref|YP_004242297.1| pyruvate/2-oxoglutarate dehydro... 310 2e-82 gi|328883634|emb|CCA56873.1| Pyruvate dehydrogenase E1 component... 308 1e-81 gi|163841387|ref|YP_001625792.1| pyruvate dehydrogenase E1 compo... 307 2e-81 gi|116669942|ref|YP_830875.1| pyruvate dehydrogenase (acetyl-tra... 307 2e-81 gi|312139114|ref|YP_004006450.1| branched-chain alpha/keto acid ... 306 2e-81 gi|297158851|gb|ADI08563.1| putative branched-chain alpha keto a... 306 3e-81 gi|51891549|ref|YP_074240.1| pyruvate dehydrogenase E1 alpha sub... 306 3e-81 gi|335430409|ref|ZP_08557303.1| pyruvate dehydrogenase (acetyl-t... 306 4e-81 gi|260907141|ref|ZP_05915463.1| pyruvate dehydrogenase (acetyl-t... 305 6e-81 gi|220913649|ref|YP_002488958.1| pyruvate dehydrogenase [Arthrob... 305 6e-81 gi|345000793|ref|YP_004803647.1| pyruvate dehydrogenase (acetyl-... 305 8e-81 gi|325673585|ref|ZP_08153276.1| pyruvate dehydrogenase complex E... 305 1e-80 gi|184201771|ref|YP_001855978.1| branched-chain alpha-keto acid ... 304 1e-80 >gi|15609634|ref|NP_217013.1| pyruvate dehydrogenase E1 component alpha subunit PdhA [Mycobacterium tuberculosis H37Rv] gi|15842025|ref|NP_337062.1| 2-oxoisovalerate dehydrogenase E1 component, alpha subunit, putative [Mycobacterium tuberculosis CDC1551] gi|31793677|ref|NP_856170.1| pyruvate dehydrogenase E1 component alpha subunit PdhA [Mycobacterium bovis AF2122/97] 39 more sequence titles Length=367 Score = 754 bits (1946), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/367 (100%), Positives = 367/367 (100%), Gaps = 0/367 (0%) Query 1 MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE 60 MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE Sbjct 1 MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE 60 Query 61 FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW 120 FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW Sbjct 61 FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW 120 Query 121 RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH 180 RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH Sbjct 121 RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH 180 Query 181 EALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY 240 EALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY Sbjct 181 EALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY 240 Query 241 AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL 300 AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL Sbjct 241 AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL 300 Query 301 QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR 360 QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR Sbjct 301 QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR 360 Query 361 AELARTD 367 AELARTD Sbjct 361 AELARTD 367 >gi|289448142|ref|ZP_06437886.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis CPHL_A] gi|289421100|gb|EFD18301.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis CPHL_A] Length=367 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/367 (99%), Positives = 367/367 (100%), Gaps = 0/367 (0%) Query 1 MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE 60 MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE Sbjct 1 MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE 60 Query 61 FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW 120 FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW Sbjct 61 FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW 120 Query 121 RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH 180 RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH Sbjct 121 RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH 180 Query 181 EALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY 240 EALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY Sbjct 181 EALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY 240 Query 241 AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL 300 AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL Sbjct 241 AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL 300 Query 301 QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR 360 QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR Sbjct 301 QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR 360 Query 361 AELARTD 367 A+LARTD Sbjct 361 AKLARTD 367 >gi|289746279|ref|ZP_06505657.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis 02_1987] gi|289686807|gb|EFD54295.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis 02_1987] Length=367 Score = 752 bits (1941), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/367 (99%), Positives = 367/367 (100%), Gaps = 0/367 (0%) Query 1 MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE 60 MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE Sbjct 1 MGEGSRRPSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTE 60 Query 61 FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW 120 FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW Sbjct 61 FVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAW 120 Query 121 RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH 180 RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH Sbjct 121 RGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVH 180 Query 181 EALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY 240 EAL+FAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY Sbjct 181 EALDFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACY 240 Query 241 AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL 300 AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL Sbjct 241 AVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYL 300 Query 301 QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR 360 QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR Sbjct 301 QDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLR 360 Query 361 AELARTD 367 AELARTD Sbjct 361 AELARTD 367 >gi|308232154|ref|ZP_07415107.2| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis SUMu001] gi|308369734|ref|ZP_07418873.2| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis SUMu002] gi|308371033|ref|ZP_07423619.2| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis SUMu003] 21 more sequence titles Length=357 Score = 733 bits (1893), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/357 (100%), Positives = 357/357 (100%), Gaps = 0/357 (0%) Query 11 MLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGEL 70 MLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGEL Sbjct 1 MLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGEL 60 Query 71 ALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQF 130 ALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQF Sbjct 61 ALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQF 120 Query 131 TTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFT 190 TTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFT Sbjct 121 TTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFT 180 Query 191 TPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARA 250 TPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARA Sbjct 181 TPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARA 240 Query 251 RAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRL 310 RAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRL Sbjct 241 RAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRL 300 Query 311 EEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 EEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD Sbjct 301 EEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 357 >gi|323718905|gb|EGB28059.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis CDC1551A] Length=355 Score = 729 bits (1883), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/355 (100%), Positives = 355/355 (100%), Gaps = 0/355 (0%) Query 13 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL Sbjct 1 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 60 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT Sbjct 61 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 120 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP Sbjct 121 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 180 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA Sbjct 181 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 240 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE Sbjct 241 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 300 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD Sbjct 301 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 355 >gi|289754606|ref|ZP_06513984.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis EAS054] gi|289695193|gb|EFD62622.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis EAS054] Length=345 Score = 709 bits (1831), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/345 (100%), Positives = 345/345 (100%), Gaps = 0/345 (0%) Query 23 VGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCRGQEAA 82 VGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCRGQEAA Sbjct 1 VGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCRGQEAA 60 Query 83 QVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPI 142 QVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPI Sbjct 61 QVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPI 120 Query 143 GTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQW 202 GTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQW Sbjct 121 GTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQW 180 Query 203 AISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAV 262 AISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAV Sbjct 181 AISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAV 240 Query 263 TYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVR 322 TYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVR Sbjct 241 TYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVR 300 Query 323 SELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 SELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD Sbjct 301 SELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 345 >gi|289570657|ref|ZP_06450884.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis T17] gi|289544411|gb|EFD48059.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis T17] Length=349 Score = 669 bits (1725), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/352 (97%), Positives = 341/352 (97%), Gaps = 7/352 (1%) Query 20 VQLVGP----DGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTP 75 +QLVGP DG A HRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTP Sbjct 1 MQLVGPGRYADGPNAAT---HRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTP 57 Query 76 CRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCC 135 CRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCC Sbjct 58 CRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCC 117 Query 136 APMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVF 195 APMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVF Sbjct 118 APMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVF 177 Query 196 YVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDG 255 YVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDG Sbjct 178 YVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDG 237 Query 256 PTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVT 315 PTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVT Sbjct 238 PTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVT 297 Query 316 ARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 ARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD Sbjct 298 ARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 349 >gi|240171578|ref|ZP_04750237.1| putative pyruvate dehydrogenase E1 component subunit alpha [Mycobacterium kansasii ATCC 12478] Length=355 Score = 627 bits (1617), Expect = 8e-178, Method: Compositional matrix adjust. Identities = 301/355 (85%), Positives = 321/355 (91%), Gaps = 0/355 (0%) Query 13 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 M+VDLEPVQL+GPDG PTAE RY RDL ETL WLYEMMVVTRELD EFVNLQRQGELAL Sbjct 1 MTVDLEPVQLIGPDGKPTAEERYSRDLSAETLCWLYEMMVVTRELDDEFVNLQRQGELAL 60 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 +TPCRGQEAAQVGAAACLR DWLFPQYRELGVYLVRGIPPGHVG AWRG+WHGGL+FTT Sbjct 61 FTPCRGQEAAQVGAAACLRAADWLFPQYRELGVYLVRGIPPGHVGAAWRGSWHGGLEFTT 120 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 KCCAPMSVP+GTQTLHAVGAAMAAQRL EDSVTV FLGDGATSEGDVHEALN A VF P Sbjct 121 KCCAPMSVPVGTQTLHAVGAAMAAQRLGEDSVTVPFLGDGATSEGDVHEALNLAGVFRVP 180 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 C+FYVQNNQWAIS PV +QTAA SIAHKAIGYGMPGIRVDGNDVLACYAVMAEAA RARA Sbjct 181 CLFYVQNNQWAISTPVRKQTAAVSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAATRARA 240 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G+GP+LIEAVTYRLGPHTTADDPTRYR Q+E+DRW LDPIPR+R YLQD GLWSQ LE+ Sbjct 241 GNGPSLIEAVTYRLGPHTTADDPTRYRDQQELDRWLALDPIPRFRRYLQDLGLWSQSLED 300 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 +V AR+ R+ELRDAVFDAPDFDVDE+FT VYA ITP L+AQR QLRAELART+ Sbjct 301 RVAARSAGQRAELRDAVFDAPDFDVDELFTAVYAHITPELEAQRRQLRAELARTE 355 >gi|296170433|ref|ZP_06852021.1| pyruvate dehydrogenase complex E1 component [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894904|gb|EFG74625.1| pyruvate dehydrogenase complex E1 component [Mycobacterium parascrofulaceum ATCC BAA-614] Length=366 Score = 615 bits (1585), Expect = 5e-174, Method: Compositional matrix adjust. Identities = 302/355 (86%), Positives = 324/355 (92%), Gaps = 0/355 (0%) Query 13 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 M+VDLEPVQLV DGTPT E RY RDL ETL WLYEMMVVTRELDTEFVNL+RQGEL L Sbjct 9 MTVDLEPVQLVAADGTPTPEHRYGRDLRAETLCWLYEMMVVTRELDTEFVNLKRQGELGL 68 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 + CRGQEAAQVGA ACLRKTDWLFPQYRELG YLVRGIPPGHVG WRGTWHGGL+FT Sbjct 69 FASCRGQEAAQVGAVACLRKTDWLFPQYRELGAYLVRGIPPGHVGAVWRGTWHGGLEFTK 128 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 KCCAP S+PIGTQ LHAVGAAMAAQRL EDSVTVAFLGDGATS GDVHEALNFAAVF TP Sbjct 129 KCCAPTSIPIGTQALHAVGAAMAAQRLGEDSVTVAFLGDGATSVGDVHEALNFAAVFATP 188 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 CVF+VQNNQWAIS+P+ +QT APSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA Sbjct 189 CVFFVQNNQWAISVPIHKQTKAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 248 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 GDGPTLIEAVTYRLGPHTT+DDP+RYR+QEEVDRWA LDPIPRYRTYLQ QGLWS RLE+ Sbjct 249 GDGPTLIEAVTYRLGPHTTSDDPSRYRTQEEVDRWAALDPIPRYRTYLQAQGLWSDRLED 308 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 +V ARAK +R+ELRDAVF APDFD++EVFTTVYAE+TPGL+AQ +QLRAEL R+D Sbjct 309 RVAARAKRMRAELRDAVFGAPDFDIEEVFTTVYAEMTPGLRAQLQQLRAELERSD 363 >gi|342857888|ref|ZP_08714544.1| PdhA [Mycobacterium colombiense CECT 3035] gi|342135221|gb|EGT88387.1| PdhA [Mycobacterium colombiense CECT 3035] Length=355 Score = 612 bits (1578), Expect = 3e-173, Method: Compositional matrix adjust. Identities = 301/355 (85%), Positives = 326/355 (92%), Gaps = 0/355 (0%) Query 13 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 M+VDLEPVQLV PDG+PT E RY R+LP ETL WLYEMMVVTRELD EFVNL+RQGEL L Sbjct 1 MTVDLEPVQLVAPDGSPTPEDRYSRELPAETLSWLYEMMVVTRELDGEFVNLKRQGELGL 60 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 + C GQEAAQVGAAACLRKTDWLFPQYRELG +LVRGIPPGHVG AWRGTWHGGL FT Sbjct 61 FASCHGQEAAQVGAAACLRKTDWLFPQYRELGAFLVRGIPPGHVGAAWRGTWHGGLDFTK 120 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 KCCAP+S+PIGTQTLHAVGAAMAAQRL EDSVT+AFLGDGATS GDVHEALNFAAVFTTP Sbjct 121 KCCAPLSIPIGTQTLHAVGAAMAAQRLGEDSVTMAFLGDGATSVGDVHEALNFAAVFTTP 180 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 CVF+VQNNQWAIS+P+S+QTAAPS+AHKAIGYGMPGIRVDGNDVLACYAV AEAAARARA Sbjct 181 CVFFVQNNQWAISVPISKQTAAPSLAHKAIGYGMPGIRVDGNDVLACYAVTAEAAARARA 240 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GPTLIEAVTYRL PHTT+DDP+RYR+Q+EVD WA L+PI RYR YLQ QGLWSQRLEE Sbjct 241 GGGPTLIEAVTYRLAPHTTSDDPSRYRTQDEVDHWAALEPIARYRNYLQGQGLWSQRLEE 300 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 +V ARAK +R+ELRDAVFDAPDFD+DEVFT+VYAEITPGLQAQR QLRAEL R+D Sbjct 301 RVAARAKRMRAELRDAVFDAPDFDIDEVFTSVYAEITPGLQAQRRQLRAELDRSD 355 >gi|183983819|ref|YP_001852110.1| pyruvate dehydrogenase E1 component (alpha subunit) PdhA [Mycobacterium marinum M] gi|183177145|gb|ACC42255.1| pyruvate dehydrogenase E1 component (alpha subunit) PdhA [Mycobacterium marinum M] Length=363 Score = 606 bits (1562), Expect = 2e-171, Method: Compositional matrix adjust. Identities = 300/355 (85%), Positives = 318/355 (90%), Gaps = 0/355 (0%) Query 13 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 M+V LEPVQLV DG PT E RY RDLPEETL WLYEMMVVTRELD EF+NL+RQGELAL Sbjct 9 MTVGLEPVQLVNADGEPTDEHRYSRDLPEETLCWLYEMMVVTRELDAEFINLKRQGELAL 68 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 + CRGQEAAQVGA ACLRKTDWLFPQYRELG YLVRGIPPGHVG AWRGTWHGGL+FT Sbjct 69 FASCRGQEAAQVGATACLRKTDWLFPQYRELGAYLVRGIPPGHVGAAWRGTWHGGLEFTK 128 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 KCCAP+SVPIGTQ LHAVGAAMAAQRL EDSVTVAFLGDGATSEGDVHEALNFAAVF Sbjct 129 KCCAPISVPIGTQALHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDVHEALNFAAVFDAG 188 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 CVFYVQNNQWAIS+PVS+QTAAPSIAHKAIGYGMPGIRVDGNDVLACYAV AEAAARAR Sbjct 189 CVFYVQNNQWAISVPVSKQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVTAEAAARARR 248 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 GDGPTLIEAVTYR+G HTTADDP RYRSQEEVD W LDPI RYR+YLQ QGLWSQRLEE Sbjct 249 GDGPTLIEAVTYRVGAHTTADDPGRYRSQEEVDHWLALDPISRYRSYLQGQGLWSQRLEE 308 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 +V AR+ +R+ELR+AVF A DFDVD+VFTTV+AEITPGLQ QR+QLRAEL R D Sbjct 309 RVAARSGRLRAELREAVFGASDFDVDDVFTTVFAEITPGLQTQRQQLRAELDRID 363 >gi|254823116|ref|ZP_05228117.1| PdhA [Mycobacterium intracellulare ATCC 13950] Length=355 Score = 603 bits (1556), Expect = 1e-170, Method: Compositional matrix adjust. Identities = 294/355 (83%), Positives = 325/355 (92%), Gaps = 0/355 (0%) Query 13 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 M+VDLEPVQLV DG+PT ERRY RDLP ETL WLYE+MV+TRELD EFVNL+RQGELAL Sbjct 1 MAVDLEPVQLVAADGSPTPERRYGRDLPAETLSWLYELMVITRELDAEFVNLKRQGELAL 60 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 + CRGQEAAQ+GAAACLRKTDWLFPQYRELG +LVRGIPPGHVG WRGTWHGGL+FT Sbjct 61 FASCRGQEAAQIGAAACLRKTDWLFPQYRELGAFLVRGIPPGHVGAVWRGTWHGGLEFTK 120 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 KCCAP+S+PIGTQTLHAVGAAMAAQRL EDSVT+AFLGDGATS GDVHEALNFAAVFTTP Sbjct 121 KCCAPLSIPIGTQTLHAVGAAMAAQRLGEDSVTLAFLGDGATSTGDVHEALNFAAVFTTP 180 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 CVF VQNNQWAIS PV +QTAAPS+AHKAIGYGMPG+RVDGNDVLACYAV AEAAARARA Sbjct 181 CVFLVQNNQWAISTPVHKQTAAPSLAHKAIGYGMPGVRVDGNDVLACYAVTAEAAARARA 240 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GPTLIEA+TYR+GPHTT+DDP+RYR+Q+EVD WA LDPI RYR YL+ QGLWS+RLEE Sbjct 241 GGGPTLIEAITYRMGPHTTSDDPSRYRTQDEVDHWAALDPIARYRCYLRAQGLWSERLEE 300 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 +V RA+ +R+ELRDAV DAPDFD+DEVFT+VYAEITPGLQAQR+QLRAEL R+D Sbjct 301 RVIGRAQRMRTELRDAVVDAPDFDIDEVFTSVYAEITPGLQAQRQQLRAELDRSD 355 >gi|118619020|ref|YP_907352.1| pyruvate dehydrogenase E1 component (alpha subunit) PdhA [Mycobacterium ulcerans Agy99] gi|118571130|gb|ABL05881.1| pyruvate dehydrogenase E1 component (alpha subunit) PdhA [Mycobacterium ulcerans Agy99] Length=355 Score = 597 bits (1538), Expect = 1e-168, Method: Compositional matrix adjust. Identities = 296/355 (84%), Positives = 314/355 (89%), Gaps = 0/355 (0%) Query 13 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 M+V LEPVQLV DG PT E RY RDLPEETL WLYEMMVVTRELD EF+NL+RQGELAL Sbjct 1 MTVGLEPVQLVNADGEPTDEHRYSRDLPEETLCWLYEMMVVTRELDAEFINLKRQGELAL 60 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 + CRGQEAAQVGA ACLRKTDWLFPQYRELG YLVRGIPPGHVG AWRGTWHGGL+FT Sbjct 61 FASCRGQEAAQVGATACLRKTDWLFPQYRELGAYLVRGIPPGHVGAAWRGTWHGGLEFTK 120 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 KCC P+SVPIGTQ LHAVGAA AAQRL EDSVTVAFLGDGATSEGDVHEALNFAAVF Sbjct 121 KCCVPISVPIGTQALHAVGAAQAAQRLGEDSVTVAFLGDGATSEGDVHEALNFAAVFDAG 180 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 CVFYVQNNQWAIS+PVS+QTAAPSIAHKAIGYGMPGIRVDGNDVLACYAV A AAARAR Sbjct 181 CVFYVQNNQWAISVPVSKQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVTAVAAARARR 240 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 GDGPTLIEAVTYR+G HTTADDP RYRSQEEVD W LDPI RYR+YLQ QGLWSQRLE Sbjct 241 GDGPTLIEAVTYRVGAHTTADDPGRYRSQEEVDHWLALDPISRYRSYLQGQGLWSQRLEV 300 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 +V AR+ +R+ELR+AVF A DFDVD+VFTTV+AEITPGLQ QR+QLRAEL R D Sbjct 301 RVAARSGRLRAELREAVFGASDFDVDDVFTTVFAEITPGLQTQRQQLRAELDRID 355 >gi|118466239|ref|YP_880907.1| pyruvate dehydrogenase E1 component, alpha subunit [Mycobacterium avium 104] gi|118167526|gb|ABK68423.1| pyruvate dehydrogenase E1 component, alpha subunit [Mycobacterium avium 104] Length=363 Score = 595 bits (1535), Expect = 3e-168, Method: Compositional matrix adjust. Identities = 291/355 (82%), Positives = 321/355 (91%), Gaps = 0/355 (0%) Query 13 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 M+VDL+PVQLV DGTPT+E RY R+LP ETL WLYEMMV+TRELD EFVNL+RQG+LAL Sbjct 9 MTVDLQPVQLVAADGTPTSEHRYSRELPAETLSWLYEMMVLTRELDGEFVNLKRQGQLAL 68 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 + CRGQEAAQVGA ACLRKTDWLFPQYRELG +LVRGIPPG+VG WRGTWHGGL FT Sbjct 69 FASCRGQEAAQVGATACLRKTDWLFPQYRELGAFLVRGIPPGNVGAVWRGTWHGGLGFTD 128 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 KCCAP+S+PIGTQTLHAVGAAMAAQRL EDSVT+AFLGDGATS GDVHEALNFAAVF TP Sbjct 129 KCCAPLSIPIGTQTLHAVGAAMAAQRLGEDSVTIAFLGDGATSVGDVHEALNFAAVFRTP 188 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 CVF+VQNNQWAIS+PV++QTA+PS+AHKAIGYGMPGIRVDGNDVLACYAV AEAAARARA Sbjct 189 CVFFVQNNQWAISLPVAKQTASPSLAHKAIGYGMPGIRVDGNDVLACYAVTAEAAARARA 248 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GPTLIEA+TYRLGPHTT+DDPTRYR+Q+EVD WA LDPIPRYR+YLQ QGLWS+RLEE Sbjct 249 GGGPTLIEAITYRLGPHTTSDDPTRYRTQDEVDHWAALDPIPRYRSYLQGQGLWSERLEE 308 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 +V RA +R+ELRDAVFDAPD DVDEVFT VYAEITP LQAQR LR EL ++D Sbjct 309 RVIGRATRMRAELRDAVFDAPDLDVDEVFTAVYAEITPELQAQRRALRTELEKSD 363 >gi|254774501|ref|ZP_05216017.1| PdhA [Mycobacterium avium subsp. avium ATCC 25291] Length=355 Score = 595 bits (1534), Expect = 4e-168, Method: Compositional matrix adjust. Identities = 292/355 (83%), Positives = 320/355 (91%), Gaps = 0/355 (0%) Query 13 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 M+VDL+PVQLV DGTPT E RY R+LP ETL WLYEMMV+TRELD EFVNL+RQG+LAL Sbjct 1 MTVDLQPVQLVAADGTPTPEHRYSRELPAETLSWLYEMMVLTRELDGEFVNLKRQGQLAL 60 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 + CRGQEAAQVGA ACLRKTDWLFPQYRELG +LVRGIPPG+VG WRGTWHGGL FT Sbjct 61 FASCRGQEAAQVGATACLRKTDWLFPQYRELGAFLVRGIPPGNVGAVWRGTWHGGLGFTD 120 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 KCCAP+S+PIGTQTLHAVGAAMAAQRL EDSVT+AFLGDGATS GDVHEALNFAAVF TP Sbjct 121 KCCAPLSIPIGTQTLHAVGAAMAAQRLGEDSVTIAFLGDGATSVGDVHEALNFAAVFRTP 180 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 CVF+VQNNQWAIS+PV++QTAAPS+AHKAIGYGMPGIRVDGNDVLACYAV AEAAARARA Sbjct 181 CVFFVQNNQWAISLPVAKQTAAPSLAHKAIGYGMPGIRVDGNDVLACYAVTAEAAARARA 240 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GPTLIEA+TYRLGPHTT+DDPTRYR+Q+EVD WA LDPIPRYR+YLQ QGLWS+RLEE Sbjct 241 GGGPTLIEAITYRLGPHTTSDDPTRYRTQDEVDHWAALDPIPRYRSYLQGQGLWSERLEE 300 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 +V RA +R+ELRDAVFDAPD DVDEVFT VYAEITP LQAQR LR EL ++D Sbjct 301 RVIGRATRMRAELRDAVFDAPDLDVDEVFTAVYAEITPELQAQRRALRTELEKSD 355 >gi|41408407|ref|NP_961243.1| PdhA [Mycobacterium avium subsp. paratuberculosis K-10] gi|41396763|gb|AAS04626.1| PdhA [Mycobacterium avium subsp. paratuberculosis K-10] gi|336460983|gb|EGO39863.1| pyruvate dehydrogenase E1 component, alpha subunit [Mycobacterium avium subsp. paratuberculosis S397] Length=363 Score = 593 bits (1530), Expect = 1e-167, Method: Compositional matrix adjust. Identities = 291/355 (82%), Positives = 320/355 (91%), Gaps = 0/355 (0%) Query 13 MSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 M+VDL+PVQLV DGTPT E RY R+LP ETL WLYEMMV+TRELD EFVNL+RQG+LAL Sbjct 9 MTVDLQPVQLVAADGTPTPEHRYSRELPAETLSWLYEMMVLTRELDGEFVNLKRQGQLAL 68 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 + CRGQEAAQVGA ACLRKTDWLFPQYRELG +LVRGIPPG+VG WRGTWHGGL FT Sbjct 69 FASCRGQEAAQVGATACLRKTDWLFPQYRELGAFLVRGIPPGNVGAVWRGTWHGGLGFTD 128 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 KCCAP+S+PIGTQ+LHAVGAAMAAQRL EDSVT+AFLGDGATS GDVHEALNFAAVF TP Sbjct 129 KCCAPLSIPIGTQSLHAVGAAMAAQRLGEDSVTIAFLGDGATSVGDVHEALNFAAVFRTP 188 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 CVF+VQNNQWAIS+PV++QTAAPS+AHKAIGYGMPGIRVDGNDVLACYAV AEAAARARA Sbjct 189 CVFFVQNNQWAISLPVAKQTAAPSLAHKAIGYGMPGIRVDGNDVLACYAVTAEAAARARA 248 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GPTLIEA+TYRLGPHTT+DDPTRYR+Q+EVD WA LDPIPRYR+YLQ QGLWS+RLEE Sbjct 249 GRGPTLIEAITYRLGPHTTSDDPTRYRTQDEVDHWAALDPIPRYRSYLQGQGLWSERLEE 308 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 +V RA +R+ELRDAVFDAPD DVDEVFT VYAEITP LQAQR LR EL ++D Sbjct 309 RVIGRATRMRAELRDAVFDAPDLDVDEVFTAVYAEITPELQAQRRALRTELEKSD 363 >gi|289762665|ref|ZP_06522043.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis GM 1503] gi|289710171|gb|EFD74187.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis GM 1503] Length=284 Score = 583 bits (1502), Expect = 2e-164, Method: Compositional matrix adjust. Identities = 283/284 (99%), Positives = 284/284 (100%), Gaps = 0/284 (0%) Query 84 VGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIG 143 +GAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIG Sbjct 1 MGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIG 60 Query 144 TQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQWA 203 TQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQWA Sbjct 61 TQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQWA 120 Query 204 ISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAVT 263 ISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAVT Sbjct 121 ISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAVT 180 Query 264 YRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVRS 323 YRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVRS Sbjct 181 YRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVRS 240 Query 324 ELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 ELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD Sbjct 241 ELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 284 >gi|333990058|ref|YP_004522672.1| pyruvate dehydrogenase E1 component (alpha subunit) PdhA [Mycobacterium sp. JDM601] gi|333486026|gb|AEF35418.1| pyruvate dehydrogenase E1 component (alpha subunit) PdhA [Mycobacterium sp. JDM601] Length=364 Score = 582 bits (1499), Expect = 5e-164, Method: Compositional matrix adjust. Identities = 274/351 (79%), Positives = 309/351 (89%), Gaps = 0/351 (0%) Query 15 VDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYT 74 V LEPVQ++GPDG PTAE RY RDLP+ETL WLYE+M +TRELDTE VNLQRQGELALY Sbjct 12 VALEPVQVIGPDGAPTAENRYSRDLPDETLCWLYELMALTRELDTELVNLQRQGELALYA 71 Query 75 PCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKC 134 CRGQEAAQ+GA ACLRKTDWLFPQYRELGV++ RGIP ++ AWRGTW+GGL+FT KC Sbjct 72 SCRGQEAAQIGATACLRKTDWLFPQYRELGVFVARGIPAWNLAAAWRGTWNGGLEFTAKC 131 Query 135 CAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCV 194 CAP+SVPIGTQ LHAVGAAM AQRL EDSVTVAF+GDGATSEGDVHEALNFAAVF PCV Sbjct 132 CAPISVPIGTQALHAVGAAMGAQRLGEDSVTVAFVGDGATSEGDVHEALNFAAVFAAPCV 191 Query 195 FYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGD 254 F+VQNNQWAIS+P+ RQTAAPS+AHKAIGYGMPGIRVDGND LACYAVMAEAA RAR G Sbjct 192 FFVQNNQWAISVPLHRQTAAPSLAHKAIGYGMPGIRVDGNDPLACYAVMAEAAERARTGG 251 Query 255 GPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQV 314 GPTL+EAVTYRLGPHTT+DDPTRYRS E +RW LDPIPRYR+YL++ G+W+QRLE++V Sbjct 252 GPTLVEAVTYRLGPHTTSDDPTRYRSSAEHERWTALDPIPRYRSYLRNAGVWTQRLEDRV 311 Query 315 TARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365 ARA+ +R+ELRDA A DFDVDEVFT+V+A++TP LQ QR LRAELAR Sbjct 312 AARAQRLRTELRDATVGAADFDVDEVFTSVFADLTPELQQQRRALRAELAR 362 >gi|108800592|ref|YP_640789.1| pyruvate dehydrogenase (lipoamide) [Mycobacterium sp. MCS] gi|119869731|ref|YP_939683.1| pyruvate dehydrogenase [Mycobacterium sp. KMS] gi|126436208|ref|YP_001071899.1| pyruvate dehydrogenase [Mycobacterium sp. JLS] gi|108771011|gb|ABG09733.1| Pyruvate dehydrogenase (lipoamide) [Mycobacterium sp. MCS] gi|119695820|gb|ABL92893.1| Pyruvate dehydrogenase (acetyl-transferring) [Mycobacterium sp. KMS] gi|126236008|gb|ABN99408.1| Pyruvate dehydrogenase (acetyl-transferring) [Mycobacterium sp. JLS] Length=356 Score = 557 bits (1436), Expect = 1e-156, Method: Compositional matrix adjust. Identities = 271/354 (77%), Positives = 307/354 (87%), Gaps = 0/354 (0%) Query 12 LMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELA 71 + V+L+PVQLVG DG+P+A++RY RDLP ETL WLYE MVVTR+LDTEFV+LQRQGELA Sbjct 1 MAGVELDPVQLVGADGSPSAQQRYSRDLPPETLAWLYETMVVTRDLDTEFVHLQRQGELA 60 Query 72 LYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFT 131 LY CRGQEAAQ+GA ACLRKTDWLFPQYRE+G +L+RGI P + WRG WHGGL+FT Sbjct 61 LYASCRGQEAAQIGATACLRKTDWLFPQYREIGAFLLRGIAPAQMAAVWRGKWHGGLEFT 120 Query 132 TKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTT 191 KCCAP+S+PIGTQ LHAVGAAMAAQRL EDSVTVAFLGDGATSEGDVHEA+N AAV+ Sbjct 121 AKCCAPISIPIGTQGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDVHEAMNLAAVYQV 180 Query 192 PCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARAR 251 PCVF+VQNNQWAIS+PV RQ A PSIAH+A GYGMPG+RVDGNDVLAC+AVM+EAAARAR Sbjct 181 PCVFFVQNNQWAISVPVQRQVAGPSIAHRAAGYGMPGVRVDGNDVLACFAVMSEAAARAR 240 Query 252 AGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLE 311 AG GPTLIEAVTYRLGPHTT+DDPTRYR Q EVDRW DPIPRYRTYLQ G+WS+RLE Sbjct 241 AGGGPTLIEAVTYRLGPHTTSDDPTRYRDQSEVDRWRARDPIPRYRTYLQGAGVWSERLE 300 Query 312 EQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365 E+V AR+K +R+ELRDAV APDFDV EVF TVY +ITP L QR++L AELA+ Sbjct 301 ERVAARSKRLRAELRDAVVGAPDFDVSEVFDTVYHDITPDLAEQRDRLLAELAK 354 >gi|120405040|ref|YP_954869.1| pyruvate dehydrogenase [Mycobacterium vanbaalenii PYR-1] gi|119957858|gb|ABM14863.1| Pyruvate dehydrogenase (acetyl-transferring) [Mycobacterium vanbaalenii PYR-1] Length=361 Score = 547 bits (1410), Expect = 9e-154, Method: Compositional matrix adjust. Identities = 259/348 (75%), Positives = 291/348 (84%), Gaps = 0/348 (0%) Query 18 EPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCR 77 EP+QLV PDG PT E RY RDLP ETL WLYE MVVTRELDTEFVNLQRQGELAL+ CR Sbjct 12 EPIQLVAPDGAPTPESRYRRDLPPETLAWLYESMVVTRELDTEFVNLQRQGELALFASCR 71 Query 78 GQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAP 137 GQEAAQ+GAAACLRKTDWLFPQYRELG +LVR I P +G WRG WHGGL FT +C AP Sbjct 72 GQEAAQIGAAACLRKTDWLFPQYRELGAFLVRAIAPAQLGALWRGRWHGGLGFTDRCVAP 131 Query 138 MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV 197 +S+PIGT LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEALN AAVF PCVF+V Sbjct 132 VSIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEALNLAAVFGAPCVFFV 191 Query 198 QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT 257 QNNQWAIS+PV RQ A P++AH+AIGYGMPG+RVDGNDVLAC+AVM +AAARAR G GPT Sbjct 192 QNNQWAISVPVERQHAGPTLAHRAIGYGMPGVRVDGNDVLACFAVMEQAAARAREGGGPT 251 Query 258 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR 317 IEAVTYR+GPHTT+DDPTRYRS EEV+ W DPI RYRTYL+ G+W+QRLEE+V R Sbjct 252 FIEAVTYRMGPHTTSDDPTRYRSDEEVEHWRARDPIARYRTYLEHTGVWTQRLEERVAHR 311 Query 318 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365 ++ +R+ELRDAV PD D+ EVF TVY +ITP L QR++L AELA+ Sbjct 312 SQRLRAELRDAVITEPDIDIGEVFDTVYHDITPDLARQRDELLAELAK 359 >gi|118467989|ref|YP_888972.1| pyruvate dehydrogenase E1 component, subunit alpha [Mycobacterium smegmatis str. MC2 155] gi|118169276|gb|ABK70172.1| pyruvate dehydrogenase E1 component, alpha subunit [Mycobacterium smegmatis str. MC2 155] Length=370 Score = 542 bits (1396), Expect = 4e-152, Method: Compositional matrix adjust. Identities = 259/359 (73%), Positives = 295/359 (83%), Gaps = 3/359 (0%) Query 10 GMLMSVDLEPVQLVGPDGTPTAER---RYHRDLPEETLRWLYEMMVVTRELDTEFVNLQR 66 G D EPVQLV DG+P+ +R RY RDLP ETL WLYE MVVTR LD EFVNLQR Sbjct 10 GYDTGFDPEPVQLVAADGSPSPDRPPSRYSRDLPPETLSWLYESMVVTRNLDVEFVNLQR 69 Query 67 QGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHG 126 QGELAL+ CRGQEAAQ+GAAACLRKTDWLFPQYRE+G +L+RGI P +G WRG WHG Sbjct 70 QGELALFASCRGQEAAQIGAAACLRKTDWLFPQYREIGAFLLRGITPAQMGAVWRGKWHG 129 Query 127 GLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFA 186 GL FT KC AP+++PIGT LHAVGAAMAAQRL EDSVTVAFLGDGATSEGD HEA N A Sbjct 130 GLSFTGKCVAPIAIPIGTHGLHAVGAAMAAQRLGEDSVTVAFLGDGATSEGDAHEAFNLA 189 Query 187 AVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEA 246 VF PCVF++QNNQWAIS+PVSRQ A P+IAH+AIGYGMPGIRVDGNDVLACYAVM+EA Sbjct 190 TVFRAPCVFFIQNNQWAISVPVSRQQAGPTIAHRAIGYGMPGIRVDGNDVLACYAVMSEA 249 Query 247 AARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLW 306 A RAR G+GPTLIEAVTYR+GPHTT+DDPTRYR EEV+ WA DPI RYRTYLQ+ G+W Sbjct 250 AERARRGEGPTLIEAVTYRMGPHTTSDDPTRYRPAEEVEAWAARDPIARYRTYLQNIGVW 309 Query 307 SQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365 ++RLEE+V AR+ + +ELRDA+ APD D E+F TVYA+ITP L QR+QL +ELA+ Sbjct 310 TERLEERVAARSSRLCAELRDAIVGAPDVDPAEMFDTVYADITPELARQRDQLLSELAK 368 >gi|289751106|ref|ZP_06510484.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis T92] gi|289691693|gb|EFD59122.1| pyruvate dehydrogenase E1 component alpha subunit pdhA [Mycobacterium tuberculosis T92] Length=259 Score = 527 bits (1358), Expect = 1e-147, Method: Compositional matrix adjust. Identities = 256/256 (100%), Positives = 256/256 (100%), Gaps = 0/256 (0%) Query 112 PPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGD 171 PPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGD Sbjct 4 PPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGD 63 Query 172 GATSEGDVHEALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRV 231 GATSEGDVHEALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRV Sbjct 64 GATSEGDVHEALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRV 123 Query 232 DGNDVLACYAVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLD 291 DGNDVLACYAVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLD Sbjct 124 DGNDVLACYAVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLD 183 Query 292 PIPRYRTYLQDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPG 351 PIPRYRTYLQDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPG Sbjct 184 PIPRYRTYLQDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPG 243 Query 352 LQAQREQLRAELARTD 367 LQAQREQLRAELARTD Sbjct 244 LQAQREQLRAELARTD 259 >gi|289444027|ref|ZP_06433771.1| pyruvate dehydrogenase E1 component pdhA [Mycobacterium tuberculosis T46] gi|289416946|gb|EFD14186.1| pyruvate dehydrogenase E1 component pdhA [Mycobacterium tuberculosis T46] Length=230 Score = 468 bits (1204), Expect = 8e-130, Method: Compositional matrix adjust. Identities = 230/230 (100%), Positives = 230/230 (100%), Gaps = 0/230 (0%) Query 138 MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV 197 MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV Sbjct 1 MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV 60 Query 198 QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT 257 QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT Sbjct 61 QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT 120 Query 258 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR 317 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR Sbjct 121 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR 180 Query 318 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD Sbjct 181 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 230 >gi|238059377|ref|ZP_04604086.1| pyruvate dehydrogenase [Micromonospora sp. ATCC 39149] gi|237881188|gb|EEP70016.1| pyruvate dehydrogenase [Micromonospora sp. ATCC 39149] Length=397 Score = 322 bits (825), Expect = 7e-86, Method: Compositional matrix adjust. Identities = 175/357 (50%), Positives = 220/357 (62%), Gaps = 1/357 (0%) Query 8 PSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQ 67 PS L+ EPV+L+ PDGTP R + + P E LR +Y MVV R D + L +Q Sbjct 35 PSAALLP-HAEPVRLLDPDGTPRPARADYPEPPVEALREMYRRMVVGRRFDAQATALTKQ 93 Query 68 GELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGG 127 G LA+Y RGQEA QVGA + DW+FP YRE + RGI P V RG WH G Sbjct 94 GRLAVYPSSRGQEACQVGAVLAVGHNDWVFPTYRESMALVSRGIDPVEVLTLLRGDWHCG 153 Query 128 LQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAA 187 AP P+ TQ +HA G A D+V +AF+GDGATSEGD HE +NFAA Sbjct 154 YDPARVRTAPQCTPLATQCVHAAGLAYGEAHQGRDTVALAFIGDGATSEGDFHEGVNFAA 213 Query 188 VFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAA 247 VF P VF+VQNN++AIS+P+SRQTAAPS+A+K +GYG+P +VDGND +A AV+ A Sbjct 214 VFKAPVVFFVQNNKYAISVPLSRQTAAPSLAYKGVGYGVPSEQVDGNDPVAVLAVLTRAV 273 Query 248 ARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWS 307 A ARAG+GP L+EA TYR+ PHT ADD TRYR EVD W DPI R TYL+ +G Sbjct 274 AHARAGNGPYLVEAHTYRMEPHTNADDATRYRDGAEVDTWRDRDPIARLETYLRTRGALD 333 Query 308 QRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELA 364 + A+A+ ++LR+ + P+ D +F VYA TP L QRE +RAELA Sbjct 334 DAAVAAIAAQAEGYAADLRERMHVQPEVDPLSLFDHVYATPTPQLVEQRELVRAELA 390 >gi|308178212|ref|YP_003917618.1| 2-oxoacid dehydrogenase E1 component subunit alpha [Arthrobacter arilaitensis Re117] gi|307745675|emb|CBT76647.1| 2-oxoacid dehydrogenase E1 component alpha chain [Arthrobacter arilaitensis Re117] Length=387 Score = 322 bits (824), Expect = 9e-86, Method: Compositional matrix adjust. Identities = 169/355 (48%), Positives = 216/355 (61%), Gaps = 7/355 (1%) Query 20 VQLVGPDGTPTAERR------YHRDLPEET-LRWLYEMMVVTRELDTEFVNLQRQGELAL 72 + L+ PDGT E + + LP L Y +V R ++ + L RQG +A+ Sbjct 32 INLLNPDGTLRPEDQQGTEPGHEYPLPSPARLLEAYSALVTGRRVNDQNSALVRQGRMAV 91 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 Y GQEA QV A+ CL + DWLFP YR+ L +G+ P V ++RG WH G Sbjct 92 YPSSHGQEACQVAASLCLGEGDWLFPTYRDTVAVLAKGVAPMEVMTSFRGEWHCGYDPKA 151 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 CAPMS P+ TQ LHAVG A AA+ ED+V VA GDGATSEGD HEALNFAAVF P Sbjct 152 YNCAPMSTPLTTQLLHAVGVAHAAKLRGEDTVVVAMCGDGATSEGDFHEALNFAAVFNLP 211 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 +F+VQNN++AIS+P+S+Q+AAPS+AHKA+GYGM G RVDGND++A A+M A AR Sbjct 212 VIFFVQNNKYAISVPLSQQSAAPSLAHKAVGYGMAGERVDGNDLMALMAIMTRAVRMARE 271 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G+GP LIEA TYR+ HT ADD RYR EV W DP+ R + YL D GL S Sbjct 272 GNGPLLIEAHTYRMQAHTNADDDKRYREDSEVQEWIAKDPVTRMKAYLDDAGLLSDETVA 331 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 ++TA A+ V LRD + + D E+F VY+ +P L Q+ L EL R + Sbjct 332 KITADAEAVAKTLRDGMNQEANTDPRELFEHVYSTKSPQLSEQQAMLVDELDREE 386 >gi|315505682|ref|YP_004084569.1| pyruvate dehydrogenase e1 component subunit alpha [Micromonospora sp. L5] gi|315412301|gb|ADU10418.1| pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit [Micromonospora sp. L5] Length=388 Score = 321 bits (823), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 171/347 (50%), Positives = 213/347 (62%), Gaps = 0/347 (0%) Query 18 EPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCR 77 EPV+L+ PDGTP R + + P ETLR +Y MVV R D + L +QG LA+Y R Sbjct 35 EPVRLLEPDGTPLPARDDYPEPPVETLREMYRRMVVGRRFDVQATALTKQGRLAVYPSAR 94 Query 78 GQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAP 137 GQEA Q+G LR TDW+FP YRE RG+ P V RG WH G AP Sbjct 95 GQEACQIGGVLALRDTDWVFPTYRESMALTARGLDPVEVLTLLRGDWHCGYDPAATHTAP 154 Query 138 MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV 197 P+ TQ +HA G A D+V +AF+GDGATSEGD HE +NFAAVF P V+ V Sbjct 155 QCTPLATQCVHAAGLAYGESYQGRDTVALAFIGDGATSEGDFHEGINFAAVFKAPVVYLV 214 Query 198 QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT 257 QNN++AIS+P+SRQTAAPS+A+K +GYG+P +VDGND +A AV+ A A ARAG GP Sbjct 215 QNNKYAISVPLSRQTAAPSLAYKGVGYGVPSEQVDGNDPVAVLAVLERAVAHARAGKGPY 274 Query 258 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR 317 L+EA TYR+ PHT ADD TRYR +EV+ W DPI R YL+ +G+ + A Sbjct 275 LVEAHTYRMEPHTNADDQTRYRDADEVEAWRDRDPIARLEAYLRSRGVLDDAAVAAIAAE 334 Query 318 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELA 364 A+ + LR + P D +F VYAE TP L QRE +RAELA Sbjct 335 AEEYAAALRRRMDAQPTVDPLSLFDHVYAEPTPQLAEQREMVRAELA 381 >gi|302867913|ref|YP_003836550.1| pyruvate dehydrogenase E1 component subunit alpha [Micromonospora aurantiaca ATCC 27029] gi|302570772|gb|ADL46974.1| pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit [Micromonospora aurantiaca ATCC 27029] Length=388 Score = 320 bits (819), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 171/347 (50%), Positives = 212/347 (62%), Gaps = 0/347 (0%) Query 18 EPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCR 77 EPV+L+ PDGTP R + + P ETLR +Y MVV R D + L +QG LA+Y R Sbjct 35 EPVRLLEPDGTPLPARDDYPEPPVETLREMYRRMVVGRRFDVQATALTKQGRLAVYPSAR 94 Query 78 GQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAP 137 GQEA Q+G LR TDW+FP YRE RG+ P V RG WH G AP Sbjct 95 GQEACQIGGVLALRDTDWVFPTYRESMALTARGLDPVEVLTLLRGDWHCGYDPAATHTAP 154 Query 138 MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV 197 P+ TQ +HA G A D+V +AF+GDGATSEGD HE +NFAAVF P V+ V Sbjct 155 QCTPLATQCVHAAGLAYGESYQGRDTVALAFIGDGATSEGDFHEGINFAAVFKAPVVYLV 214 Query 198 QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT 257 QNN++AIS+P+SRQTAAPS+A+K +GYG+P +VDGND +A AV+ A A ARAG GP Sbjct 215 QNNKYAISVPLSRQTAAPSLAYKGVGYGVPSEQVDGNDPVAVLAVLERAVAHARAGKGPY 274 Query 258 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR 317 L+EA TYR+ PHT ADD TRYR +EV+ W DPI R YL+ +G + A Sbjct 275 LVEAHTYRMEPHTNADDQTRYRDADEVEAWRDRDPIARLEAYLRARGALDDAAVAAIAAE 334 Query 318 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELA 364 A+ + LR + P D +F VYAE TP L QRE +RAELA Sbjct 335 AEEYAAALRRRMDSQPTADPLSLFDHVYAEPTPQLAEQREMVRAELA 381 >gi|145594629|ref|YP_001158926.1| pyruvate dehydrogenase [Salinispora tropica CNB-440] gi|145303966|gb|ABP54548.1| Pyruvate dehydrogenase (acetyl-transferring) [Salinispora tropica CNB-440] Length=382 Score = 319 bits (818), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 169/346 (49%), Positives = 213/346 (62%), Gaps = 0/346 (0%) Query 18 EPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCR 77 E ++L+ P GTP + P E L LY MV+ R D + L +QG LA+Y R Sbjct 29 EQIRLLDPAGTPLPAHPDYPAPPVEVLVELYRRMVLGRRFDLQATALTKQGRLAVYPSAR 88 Query 78 GQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAP 137 GQEA QVGA LR DW+FP YRE RGI P V RG WH G + AP Sbjct 89 GQEACQVGAILALRDDDWVFPTYRESMALTARGIDPVEVLTLLRGDWHCGYDPAVRRTAP 148 Query 138 MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV 197 P+ TQ +HA G A D+V +AF+GDGATSEGD HE +NFAAVF P V++V Sbjct 149 QCTPLATQCVHAAGLAYGEAYQGRDTVALAFIGDGATSEGDFHEGVNFAAVFKAPVVYFV 208 Query 198 QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT 257 QNNQ+AIS+P+SRQTAAPS+A+K +GYG+P +VDGND +A AV+ A A ARAG GP Sbjct 209 QNNQYAISVPLSRQTAAPSLAYKGVGYGVPSEQVDGNDPVAVLAVLNRAVAHARAGHGPF 268 Query 258 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR 317 L+EA TYR+ PHT ADD RYR +EV W DP+ R T+L+D+G +V A+ Sbjct 269 LVEAHTYRMEPHTNADDAARYRDADEVASWQDRDPVVRLETHLRDRGALDDSTVARVAAQ 328 Query 318 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAEL 363 A+ ++LR+ + D P D +F VYAE TP L QREQ+RAEL Sbjct 329 AEEYAADLRERMHDKPTVDPLTLFDHVYAEPTPQLVEQREQVRAEL 374 >gi|330468696|ref|YP_004406439.1| pyruvate dehydrogenase e1 component subunit alpha [Verrucosispora maris AB-18-032] gi|328811667|gb|AEB45839.1| pyruvate dehydrogenase (acetyl-transferring) e1 component, alpha subunit [Verrucosispora maris AB-18-032] Length=388 Score = 317 bits (813), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 172/359 (48%), Positives = 218/359 (61%), Gaps = 1/359 (0%) Query 8 PSGMLMSVDLEPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQ 67 PS LM EPV+L+ DGTP R + + P E LR +Y MV+ R D + L +Q Sbjct 26 PSAGLMP-QAEPVRLLNSDGTPLPSRPDYPEPPVEALREMYRRMVIGRRFDAQATALTKQ 84 Query 68 GELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGG 127 G LA+Y RGQEA QVG LR DW+FP YRE RGI P V RG WH G Sbjct 85 GRLAVYPSSRGQEACQVGGVLALRDDDWVFPTYRESMALTARGIDPVEVLTLLRGDWHCG 144 Query 128 LQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAA 187 T AP P+ TQ +HA G A D+V + ++GDGATSEGD HE +NFAA Sbjct 145 YDPTAVRTAPQCTPLATQCVHAAGLAYGESYQGRDTVALVYIGDGATSEGDFHEGVNFAA 204 Query 188 VFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAA 247 VF P V++VQNN++AIS+P+SRQTAAP++A+K +GYG+P +VDGND +A AV+ A Sbjct 205 VFKAPVVYFVQNNRYAISVPLSRQTAAPTLAYKGVGYGVPSEQVDGNDPVAVLAVLNRAV 264 Query 248 ARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWS 307 A ARAG GP L+EA TYR+ PHT ADD TRYR EEV+ W DPI R +YL+ + + Sbjct 265 AHARAGKGPYLVEAHTYRMEPHTNADDQTRYRDAEEVEAWRERDPITRLESYLRAREVLD 324 Query 308 QRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELART 366 ++ A+ + LR+ + P D +F VYAE TP L QREQ+RAELA T Sbjct 325 DAAVAEIAEEAEAYAARLRERMNVQPTVDPLSLFEHVYAEPTPQLVEQREQVRAELAAT 383 >gi|159037836|ref|YP_001537089.1| pyruvate dehydrogenase [Salinispora arenicola CNS-205] gi|157916671|gb|ABV98098.1| Pyruvate dehydrogenase (acetyl-transferring) [Salinispora arenicola CNS-205] Length=382 Score = 314 bits (804), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 165/346 (48%), Positives = 212/346 (62%), Gaps = 0/346 (0%) Query 18 EPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCR 77 E ++L+ P GTP + + P E L LY MV+ R D + L +QG LA+Y R Sbjct 29 EQIRLLDPAGTPLPAHPDYPEPPVEALVELYRRMVIGRRFDQQATALTKQGRLAVYPSAR 88 Query 78 GQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAP 137 GQEA QVGA LR DW+FP YRE RGI P V RG WH G + AP Sbjct 89 GQEACQVGAVLALRDDDWVFPTYRESMALTARGIDPVEVLTLLRGDWHCGYDPVLRRSAP 148 Query 138 MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV 197 P+ TQ +HA G A ++V + F+GDGATSEGD HE +NFAAVF P V++V Sbjct 149 QCTPLATQCVHAAGLAYGEAYQGRETVALTFIGDGATSEGDFHEGVNFAAVFKAPVVYFV 208 Query 198 QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT 257 QNN++AIS+P+SRQTAAPS+A+K +GYG+P +VDGND +A AV+ A A ARAG GP Sbjct 209 QNNRYAISVPLSRQTAAPSLAYKGVGYGVPSEQVDGNDPVAVLAVLTRAVAHARAGHGPF 268 Query 258 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR 317 L+EA TYR+ PHT ADD TRYR +EV W DP+ R TYL+ + + +V + Sbjct 269 LVEAHTYRMEPHTNADDATRYRDADEVAVWQDRDPVARLETYLRARRALDDTIVARVAGQ 328 Query 318 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAEL 363 A+ ++LR+ + D P D +F VYAE TP L QREQ+RAEL Sbjct 329 AEEYAADLRERMHDKPTVDPMTLFDHVYAEPTPQLAEQREQVRAEL 374 >gi|289706157|ref|ZP_06502524.1| dehydrogenase E1 component [Micrococcus luteus SK58] gi|289557119|gb|EFD50443.1| dehydrogenase E1 component [Micrococcus luteus SK58] Length=400 Score = 313 bits (802), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 165/355 (47%), Positives = 221/355 (63%), Gaps = 7/355 (1%) Query 20 VQLVGPDGTPTA------ERRYHRDLP-EETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 +QL+G DGT A E + LP +E L Y +V+ R ++ + L RQG +A+ Sbjct 42 IQLIGEDGTLLAPEEQGTEPGHEYPLPSDEELLAAYRHLVIGRRVNDQAYALVRQGRMAV 101 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 Y GQEA++V AA CL + DWLFP YR+ + RG+PP V VA++GTWH G Sbjct 102 YPSSHGQEASEVAAAVCLGEDDWLFPTYRDTVAVIARGVPPLEVMVAYQGTWHQGYDPRK 161 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 + S P+ TQ LHAVG A AA+ E+ V +A +GDG TSEGD HEALNFAAVF P Sbjct 162 HHVSIQSTPLTTQMLHAVGMAKAARLRGEEVVCLAMVGDGGTSEGDFHEALNFAAVFKLP 221 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 +F+VQNN++AIS+P ++Q+AAPS+AHKA+GYG+ G RVDGND+ A AV+ A R Sbjct 222 VIFFVQNNKFAISVPFAKQSAAPSLAHKAVGYGLAGERVDGNDLGALLAVLGRAVELCRQ 281 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GP L+EA TYR+ HT DDP+RYR EV W DP+ R YL+ G ++ + Sbjct 282 GQGPFLVEADTYRMQAHTNTDDPSRYRDDAEVKEWEARDPLRRMTAYLESTGALTEEVSA 341 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 Q+ A+ V +LRDA+ + D E+F VY+ TP L AQR QL EL+R++ Sbjct 342 QIARDAEDVAQQLRDAMNAETELDPLELFDHVYSVQTPQLAAQRAQLAEELSRSE 396 >gi|239918260|ref|YP_002957818.1| pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component alpha subunit [Micrococcus luteus NCTC 2665] gi|281415547|ref|ZP_06247289.1| pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component alpha subunit [Micrococcus luteus NCTC 2665] gi|239839467|gb|ACS31264.1| pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component alpha subunit [Micrococcus luteus NCTC 2665] Length=400 Score = 312 bits (800), Expect = 5e-83, Method: Compositional matrix adjust. Identities = 165/355 (47%), Positives = 220/355 (62%), Gaps = 7/355 (1%) Query 20 VQLVGPDGTPTA------ERRYHRDLPE-ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 +QL+G DGT A E + LP E L Y +V+ R ++ + L RQG +A+ Sbjct 42 IQLIGEDGTLLAPEEQGTEPGHEYPLPSAEELLAAYRHLVIGRRVNDQAYALVRQGRMAV 101 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 Y GQEA++V AA CL + DWLFP YR+ + RG+PP V VA++GTWH G Sbjct 102 YPSSHGQEASEVAAAVCLGEDDWLFPTYRDTVAVIARGVPPLEVMVAYQGTWHQGYDPQK 161 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 + S P+ TQ LHAVG A AA+ E+ V +A +GDG TSEGD HEALNFAAVF P Sbjct 162 HRVSIQSTPLTTQMLHAVGMAKAARLRGEEVVCLAMVGDGGTSEGDFHEALNFAAVFKLP 221 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 +F+VQNN++AIS+P ++Q+AAPS+AHKA+GYG+ G RVDGND+ A AV+ A R Sbjct 222 VIFFVQNNKFAISVPFAKQSAAPSLAHKAVGYGLAGERVDGNDLGALLAVLGRAVELCRQ 281 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GP L+EA TYR+ HT DDP+RYR EV W DP+ R YL+ G ++ + Sbjct 282 GQGPFLVEADTYRMQAHTNTDDPSRYRDDAEVKEWEARDPLRRMTAYLESTGALTEEVSA 341 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 Q+ A+ V +LRDA+ + D E+F VY+ TP L AQR QL EL+R++ Sbjct 342 QIARDAEDVAQQLRDAMNAETELDPLELFDHVYSVQTPQLAAQRAQLAEELSRSE 396 >gi|290963053|ref|YP_003494235.1| pyruvate dehydrogenase E1 protein subunit alpha [Streptomyces scabiei 87.22] gi|260652579|emb|CBG75712.1| PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (ALPHA SUBUNIT) PDHA (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE) [Streptomyces scabiei 87.22] Length=384 Score = 312 bits (799), Expect = 7e-83, Method: Compositional matrix adjust. Identities = 178/358 (50%), Positives = 223/358 (63%), Gaps = 3/358 (0%) Query 10 GMLMSVDLEPVQLVGPDGTPTAER-RYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQG 68 G+L S L PV+ V DGTP A + + P E LR + MV+ R DT+ L +QG Sbjct 12 GLLPS--LTPVRFVAEDGTPVARPPAAYAEPPVEILREAHRRMVLGRRFDTQATALTKQG 69 Query 69 ELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGL 128 LA+Y RGQEA QVGAA LR DWLFP YR+ + RGI P V RG WH G Sbjct 70 RLAVYPSSRGQEACQVGAALALRPDDWLFPTYRDSVALVTRGIDPVEVLTLLRGEWHCGY 129 Query 129 QFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAV 188 AP P+ TQ LHA G A + +R ED V +A +GDGATSEGD HEALNFAAV Sbjct 130 DPAATRTAPQCTPLATQVLHATGMAESLRRKGEDGVAMALVGDGATSEGDFHEALNFAAV 189 Query 189 FTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAA 248 F P VF VQNN++AIS+P++RQTAAP++A+K +G+GM +VDGND +A AV+ EA A Sbjct 190 FRAPVVFLVQNNKYAISVPLARQTAAPALAYKGVGHGMRSEQVDGNDPVAVLAVLTEAVA 249 Query 249 RARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQ 308 ARAG GP L+EA TYR+ HT ADD TRYR +EV+RW DP+ R TYL+ +G + Sbjct 250 HARAGHGPFLVEAHTYRMDAHTNADDATRYRDADEVERWRAADPLIRLETYLRARGALTD 309 Query 309 RLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELART 366 + V A+ + +ELR + D E+F VYAE+TP L+ QR L AELA T Sbjct 310 QDIAAVGEEAEELAAELRAGMNAETVGDPLELFDHVYAELTPQLREQRALLAAELAET 367 >gi|163839304|ref|YP_001623709.1| pyruvate dehydrogenase E1 component alpha subunit [Renibacterium salmoninarum ATCC 33209] gi|162952780|gb|ABY22295.1| pyruvate dehydrogenase E1 component alpha subunit [Renibacterium salmoninarum ATCC 33209] Length=427 Score = 312 bits (799), Expect = 7e-83, Method: Compositional matrix adjust. Identities = 168/342 (50%), Positives = 210/342 (62%), Gaps = 4/342 (1%) Query 20 VQLVGPDGTPTAERRYHR---DLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPC 76 +QLV +G A Y R D+ +E L LYE M+V R +DTE LQRQGELAL+ P Sbjct 76 IQLVNANGERVANPEYDRWVADVTDEDLASLYEDMIVIRRIDTEATALQRQGELALWAPL 135 Query 77 RGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCA 136 GQEAAQ+G+ L K D++FP YRE GV VRGI + WRG HGG A Sbjct 136 LGQEAAQIGSGRALEKDDFVFPSYRENGVAYVRGINLVNSLRIWRGNTHGGWDPYEFNMA 195 Query 137 PMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFY 196 + IG QTLHA G AM DS + + GDGATS+GDV+EA+ FAA F P VF+ Sbjct 196 TPQIIIGAQTLHATGYAMGVVNDGADSAVITYFGDGATSQGDVNEAMIFAASFQAPVVFF 255 Query 197 VQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGP 256 QNN WAIS PV Q A +IA +A G+G+P +RVDGNDVLA A A RAR+G GP Sbjct 256 CQNNHWAISEPVGLQ-AHKAIADRAPGFGIPSMRVDGNDVLAVLAATRVALDRARSGGGP 314 Query 257 TLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTA 316 + IEAVTYR+GPHTTADDPTRYR E++ WA DPI R L +GL + L+ VTA Sbjct 315 SFIEAVTYRMGPHTTADDPTRYRDANELEDWAAKDPIARLAALLDSKGLLTDELKAGVTA 374 Query 317 RAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQ 358 ++ V ELR + P+ +V +VF VY+E L+ Q++ Sbjct 375 KSDEVAKELRANTINLPEPEVMDVFNNVYSEPNSALERQKDH 416 >gi|331696888|ref|YP_004333127.1| pyruvate dehydrogenase [Pseudonocardia dioxanivorans CB1190] gi|326951577|gb|AEA25274.1| Pyruvate dehydrogenase (acetyl-transferring) [Pseudonocardia dioxanivorans CB1190] Length=358 Score = 311 bits (796), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 160/316 (51%), Positives = 201/316 (64%), Gaps = 0/316 (0%) Query 48 YEMMVVTRELDTEFVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYL 107 Y +V R L+ + L RQG LA+Y RGQEA QV A+ L DWLFP YR+ Sbjct 38 YRRLVSARRLNEQAGALVRQGRLAVYPSSRGQEACQVACASVLADDDWLFPTYRDTAAIA 97 Query 108 VRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVA 167 RG+ P V RG WH G T AP + P+ TQ LHAVG AA+ ED+V +A Sbjct 98 ARGVDPVEVLSMLRGDWHCGYDPTVHKVAPQATPLATQLLHAVGVGHAARLKGEDTVVMA 157 Query 168 FLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMP 227 GDGATSEGD HEALNFAAVF P VF+VQNN++AIS+P++RQ+ APS+A KAIGYGMP Sbjct 158 LCGDGATSEGDFHEALNFAAVFAAPVVFFVQNNKYAISVPLARQSVAPSLAAKAIGYGMP 217 Query 228 GIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRW 287 G+RVDGND++ V+AEA RARAG GPTL+EA TYR+ HT ADD TRYR+ +EV W Sbjct 218 GVRVDGNDLVVLEQVLAEAVGRARAGQGPTLVEADTYRMESHTNADDATRYRTDDEVAEW 277 Query 288 ATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAE 347 DP+ R +TYL G + E+++TA A+ + + +R + D +E+F VY Sbjct 278 VGRDPVVRVKTYLTAVGALDEAREQRITAAAEEMAASVRAGLGTEAPVDPEELFAHVYGT 337 Query 348 ITPGLQAQREQLRAEL 363 TP L QR LR EL Sbjct 338 PTPQLVEQRAALRIEL 353 >gi|302529578|ref|ZP_07281920.1| pyruvate dehydrogenase E1 component alpha subunit [Streptomyces sp. AA4] gi|302438473|gb|EFL10289.1| pyruvate dehydrogenase E1 component alpha subunit [Streptomyces sp. AA4] Length=366 Score = 310 bits (795), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 170/345 (50%), Positives = 221/345 (65%), Gaps = 1/345 (0%) Query 18 EPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCR 77 EP+ LV DGTPT + + LR LY MV R DT+ L +QG LA+Y R Sbjct 17 EPLGLVTADGTPTPDPALAMPADDVLLR-LYRGMVSGRRFDTQATALTKQGRLAVYPSAR 75 Query 78 GQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAP 137 GQEAA++G+ LR DWLFP YR+ + RG+ P V RG WH G AP Sbjct 76 GQEAAEIGSILALRPQDWLFPTYRDSMAVVARGVDPVEVLTLLRGDWHCGYDPYRANVAP 135 Query 138 MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV 197 P+ T TLHAVG A AA+ ED+V++ +GDGATSEGD HEALNFAAV+ P VF V Sbjct 136 QCTPLATNTLHAVGFAHAARVKGEDTVSLVLVGDGATSEGDTHEALNFAAVWKAPVVFLV 195 Query 198 QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT 257 QNN +AIS+P+ +QTAAPS+A+K +GYGMP + VDGND A +AV+ +A ARA AG+GPT Sbjct 196 QNNGYAISVPLEKQTAAPSLAYKGVGYGMPSVLVDGNDAAAVHAVVEQAVARAAAGEGPT 255 Query 258 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR 317 LIEAVTYR+ HT ADD TRYR + EV++W T DPI R + YL D+GL + ++++ AR Sbjct 256 LIEAVTYRMESHTNADDATRYREKAEVEQWLTRDPISRLKQYLTDRGLLDDKAQQEIDAR 315 Query 318 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAE 362 A+ + LR+ + + D ++F VYAE T L+ Q +L E Sbjct 316 AEEEAAALRERMNVDTELDPADLFRHVYAEPTAALRQQAAELAHE 360 >gi|295695284|ref|YP_003588522.1| pyruvate dehydrogenase E1 component subunit alpha [Bacillus tusciae DSM 2912] gi|295410886|gb|ADG05378.1| pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit [Bacillus tusciae DSM 2912] Length=361 Score = 310 bits (795), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 166/334 (50%), Positives = 210/334 (63%), Gaps = 7/334 (2%) Query 38 DLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLF 97 DL E+ L +Y MV+ R D +NLQRQG + Y P GQEAAQ+G+ A L K DW+F Sbjct 28 DLAEDRLVGMYRGMVLARTFDERALNLQRQGRIGTYAPFSGQEAAQIGSFAALEKDDWVF 87 Query 98 PQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQ 157 P YREL + G+P + G G P+ + I +Q LHAVGA A + Sbjct 88 PSYRELAGMIYHGLPMERALLYSMGHPDGAKMPEDSRMFPVQIVIASQLLHAVGAGWACR 147 Query 158 RLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSI 217 E SV A+ GDGATSEGD HEALN A+VF+ P VF+ QNN WAIS+PVS Q + ++ Sbjct 148 LKGERSVAAAYFGDGATSEGDFHEALNLASVFSVPVVFFCQNNGWAISVPVSHQMRSATV 207 Query 218 AHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTR 277 A +A+ YG+ GIRVDGNDVLA Y M A RARAG+GPTL+EAVTYRLGPHTTADDPTR Sbjct 208 AQRAVAYGIEGIRVDGNDVLAVYEGMLRAVDRARAGEGPTLVEAVTYRLGPHTTADDPTR 267 Query 278 YRSQEEVDRW-ATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVRSELRDAVFDA---P 333 YR +EE+ RW DPI R+R +L+++G+WS EEQ A + R + +AV A P Sbjct 268 YRDEEELKRWRERRDPIVRFRKFLENRGIWS---EEQERAEWEQARRAVDEAVVRAESYP 324 Query 334 DFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 D F VYA +TP L QR++ RA +R + Sbjct 325 KADPSFAFEHVYASMTPDLCNQRDEWRARASRRE 358 >gi|325964391|ref|YP_004242297.1| pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component subunit alpha [Arthrobacter phenanthrenivorans Sphe3] gi|323470478|gb|ADX74163.1| pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component alpha subunit [Arthrobacter phenanthrenivorans Sphe3] Length=414 Score = 310 bits (794), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 166/353 (48%), Positives = 213/353 (61%), Gaps = 7/353 (1%) Query 20 VQLVGPDG--TPTAERR----YHRDLP-EETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 +Q+V PDG P E+ + LP +E L YE +VV R ++ + L RQG +A+ Sbjct 49 IQMVAPDGRLIPEGEQGTEPGHEYPLPSDEELLAAYEQLVVGRRVNDQNSALVRQGRMAV 108 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 Y GQEA QV AA CL DW+FP YR+ + RG+ P V +RG WHGG Sbjct 109 YPSSHGQEACQVAAALCLSGGDWMFPTYRDAVAVMTRGVDPVQVMTIFRGDWHGGFDPLQ 168 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 P+ TQ LHAVG A AA+ ED+V +A GDGATSEGD HEALNFAAVF P Sbjct 169 HKVGIQCTPLTTQLLHAVGVAHAAKLRGEDTVVLAMCGDGATSEGDFHEALNFAAVFHLP 228 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 +F+VQNN++AIS+P++ Q+ APS+AHKA+GYGM G RVDGNDV+A AV+ A R Sbjct 229 VIFFVQNNKYAISVPLAHQSVAPSLAHKAVGYGMAGERVDGNDVVALLAVLDRAVKLTRE 288 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GP L+EA TYR+ HT ADD TRYR EV W DP+ R R YL D+GL E Sbjct 289 GSGPLLVEANTYRMQAHTNADDDTRYRESSEVAEWRAKDPVNRMRAYLTDRGLLDDDGEA 348 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365 ++ A+ V ++LRD + + D E+F V+ + TP L+ Q L ELAR Sbjct 349 RIAVHAEAVAAQLRDGLSEDVPVDPQELFRHVFEKPTPQLKEQSALLADELAR 401 >gi|328883634|emb|CCA56873.1| Pyruvate dehydrogenase E1 component alpha subunit [Streptomyces venezuelae ATCC 10712] Length=392 Score = 308 bits (788), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 160/344 (47%), Positives = 211/344 (62%), Gaps = 1/344 (0%) Query 18 EPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCR 77 E VQL+ P+G Y DL E LR LY MV+TR D E +LQRQGEL L+ Sbjct 39 ELVQLLTPEGERVQHPDYDIDLSAEELRGLYRDMVLTRRFDAEATSLQRQGELGLWASLL 98 Query 78 GQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAP 137 GQEAAQ+G+ LR D++FP YRE GV VRG+ P ++ +RG HGG + Sbjct 99 GQEAAQIGSGRALRDDDYVFPTYREHGVAWVRGVDPTNLLGMFRGVNHGGWDPNSNNFHL 158 Query 138 MSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYV 197 ++ IG+QTLHA G AM + DS +A+ GDGA+S+GDV+EA F+AV+ P VF+ Sbjct 159 YTIVIGSQTLHATGYAMGIAKDGADSAVIAYFGDGASSQGDVNEAFTFSAVYNAPVVFFC 218 Query 198 QNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPT 257 QNNQWAIS P +QT P + +A G+G PG+RVDGNDVLAC AV A RAR G+GPT Sbjct 219 QNNQWAISEPTEKQTRVP-LYQRARGFGFPGVRVDGNDVLACLAVTRSALERARRGEGPT 277 Query 258 LIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTAR 317 L+EA TYR+G HTT+DDPT+YR EE + W DPI R + YL+ +G + E + A Sbjct 278 LVEAFTYRMGAHTTSDDPTKYRRDEEREAWEAKDPILRLKAYLEREGHADEAFFEALEAE 337 Query 318 AKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRA 361 ++ + +R+ V PD D +F VYA+ + +R Q A Sbjct 338 SEALGKRVREGVRTMPDPDDMAIFENVYADGHALVDEERAQFAA 381 >gi|163841387|ref|YP_001625792.1| pyruvate dehydrogenase E1 component alpha subunit [Renibacterium salmoninarum ATCC 33209] gi|162954863|gb|ABY24378.1| pyruvate dehydrogenase E1 component alpha subunit [Renibacterium salmoninarum ATCC 33209] Length=392 Score = 307 bits (786), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 161/353 (46%), Positives = 211/353 (60%), Gaps = 5/353 (1%) Query 18 EPVQLVGPDG--TPTAERRYHRDLP---EETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 E +Q+V P G + R+ + P + L Y +V+ R + + L RQG +A+ Sbjct 35 EQIQMVDPQGRRSEPGLRQAGHEYPVPDDAALLEAYAQLVIGRRFNDQNSALVRQGRMAV 94 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 Y GQEA QV AA CL + DWLFP YR+ + RG+ P +RG WHGG Sbjct 95 YPSSHGQEACQVAAALCLDEGDWLFPTYRDAVAVMSRGVDPVEAMTLFRGDWHGGYDPMK 154 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 P+ TQ LHAVG A AA+ E++V +A GDGATSEGD HEALNFAAVF P Sbjct 155 YKVGIQCTPLTTQLLHAVGVAHAAKLRGENTVVMALCGDGATSEGDFHEALNFAAVFNLP 214 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 +F+VQNN++AIS+P+++Q+ APS+AHKA+GYGM G VDGNDV+A AV+ A A AR Sbjct 215 VIFFVQNNKYAISVPLAQQSVAPSLAHKAVGYGMAGEHVDGNDVVALLAVLKRAVALARE 274 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GP L+EA TYR+ HT ADD TRYR EV W DP+ R R +L+ + L E Sbjct 275 GSGPLLVEANTYRIQSHTNADDATRYRQDSEVAEWLEKDPVARMRAFLRAEALLDDDGEA 334 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365 ++ ARA+ V ++LRD + PD D ++F +Y E P L Q QL EL R Sbjct 335 EIVARAEIVATQLRDGMNSEPDIDPQDLFRFLYTEPNPQLDEQSAQLAEELRR 387 >gi|116669942|ref|YP_830875.1| pyruvate dehydrogenase (acetyl-transferring) [Arthrobacter sp. FB24] gi|116610051|gb|ABK02775.1| Pyruvate dehydrogenase (acetyl-transferring) [Arthrobacter sp. FB24] Length=392 Score = 307 bits (786), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 169/348 (49%), Positives = 210/348 (61%), Gaps = 4/348 (1%) Query 20 VQLVGPDGTPTAERRYH---RDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPC 76 VQL+ P G + +Y RD+ +E L LYE MVV R +DTE LQRQGEL L+ P Sbjct 31 VQLITPGGERVSHPQYDAWVRDVSDEQLGSLYEDMVVIRRIDTEATALQRQGELGLWPPL 90 Query 77 RGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCA 136 GQEA+Q+G+A LR D++F YRE GV RG+ + WRG G T A Sbjct 91 LGQEASQIGSARSLRDDDFVFSSYRENGVAYCRGVDLADILKVWRGNASAGWDPYTINMA 150 Query 137 PMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFY 196 + IG QTLHA G AM Q DSV + + GDGATSEGDV+EA+ FAA F +P +F+ Sbjct 151 TPQIIIGAQTLHATGYAMGIQNDGADSVAITYFGDGATSEGDVNEAMVFAASFQSPVIFF 210 Query 197 VQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGP 256 QNN WAIS PV Q+ IA +A G+G+PGIRVDGNDVLA A EA RAR G GP Sbjct 211 CQNNHWAISEPVRLQSHI-RIADRAAGFGIPGIRVDGNDVLAVMAATREALERARHGGGP 269 Query 257 TLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTA 316 T IEAVTYR+GPHTTADDPTRYR E++ WA DPI R R L+ +GL + LE +V A Sbjct 270 TFIEAVTYRMGPHTTADDPTRYRDANELEDWAAKDPIARVRGLLERKGLLTDELEGRVAA 329 Query 317 RAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELA 364 +A V ++R + PD ++F VY+ L Q + LA Sbjct 330 KADAVARDMRAGCINMPDPQPLDIFKHVYSTPNSWLDRQEDHYSRYLA 377 >gi|312139114|ref|YP_004006450.1| branched-chain alpha/keto acid dehydrogenase e1 alpha subunit [Rhodococcus equi 103S] gi|311888453|emb|CBH47765.1| branched-chain alpha/keto acid dehydrogenase E1 alpha subunit [Rhodococcus equi 103S] Length=365 Score = 306 bits (785), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 170/353 (49%), Positives = 213/353 (61%), Gaps = 14/353 (3%) Query 19 PVQLVGPDGTPTAERRYHR--------DLPEETLRWLYEMMVVTRELDTEFVNLQRQGEL 70 PVQLV PDG +R HR D+ E LR LYE +VV+R +DTE LQRQG+L Sbjct 8 PVQLVQPDG-----QRVHRPDYAALVSDVGPEQLRALYEDLVVSRRIDTEATALQRQGQL 62 Query 71 ALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQF 130 ++ P GQEAAQVG+A L + D++F YRE V RG+ P + WRG H G Sbjct 63 GIWAPLLGQEAAQVGSARALERDDYIFTSYREHAVAYCRGVDPDVMTRMWRGCAHSGWDP 122 Query 131 TTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFT 190 T ++ +G Q LHA G A+ A + TV + GDGATS+GD+ EAL FAA Sbjct 123 ATVNMTNPAIVVGAQGLHATGYALGAHLDGAEIATVVYFGDGATSQGDLSEALGFAATLA 182 Query 191 TPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARA 250 P VF+ QNNQWAIS PV Q+ P IA +A GYGMP ++VDGNDVLA AV EAA RA Sbjct 183 APVVFFCQNNQWAISEPVHLQSPTP-IAARAAGYGMPAVQVDGNDVLAVLAVTREAARRA 241 Query 251 RAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRL 310 R G GP+ +EAVTYR+GPHTT+DDPTRYR+ E + W DPI R R L+ +GL+ Sbjct 242 RDGGGPSFVEAVTYRMGPHTTSDDPTRYRTAAESELWRARDPIDRMRRLLEREGLFDAEF 301 Query 311 EEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAEL 363 + +V RA V + LR +APD DE+F VYA P + +R RA L Sbjct 302 DARVQGRADDVATRLRAGALEAPDPGPDELFEHVYATGHPLIDEERAAYRAYL 354 >gi|297158851|gb|ADI08563.1| putative branched-chain alpha keto acid dehydrogenase E1 alpha subunit [Streptomyces bingchenggensis BCW-1] Length=384 Score = 306 bits (785), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 172/361 (48%), Positives = 216/361 (60%), Gaps = 10/361 (2%) Query 4 GSRRPSGMLMSVDL-EPVQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFV 62 G++R S + D E VQL+ P+G Y D + LR +Y MV+TR D E Sbjct 15 GAKRTSAKRRTADQPELVQLLTPEGERVEHPEYSLDPTPDELRAMYRDMVLTRRFDGEAT 74 Query 63 NLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRG 122 LQRQGEL L+ GQEAAQ+G+ L+ D++FP YRE GV RG+ P ++ +RG Sbjct 75 TLQRQGELGLWASLLGQEAAQIGSGRALQDDDYVFPTYREHGVAWCRGVDPVNLLGMFRG 134 Query 123 TWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEA 182 HGG + ++ IG+QTLHA G AM + DS +A+ GDGA+S+GDV EA Sbjct 135 VNHGGWDPNSNNFHLYTIVIGSQTLHATGYAMGVAKDGADSAVLAYFGDGASSQGDVAEA 194 Query 183 LNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAV 242 FAAV+ P VF+ QNNQWAIS P RQT P + +A GYG PG+RVDGNDVLAC AV Sbjct 195 FTFAAVYNAPVVFFCQNNQWAISEPTERQTRVP-LYQRAQGYGFPGVRVDGNDVLACLAV 253 Query 243 MAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQD 302 A RAR G GP LIEA TYR+G HTT+DDPTRYR EE + W T DPI R RTYL Sbjct 254 TKAALERARTGQGPMLIEAFTYRMGAHTTSDDPTRYRRAEERELWETKDPISRLRTYLTA 313 Query 303 QGL----WSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQ 358 QGL + LE++ A AK V RD+V PD D +F +YA+ P + +R Q Sbjct 314 QGLADDAFFADLEKESDALAKRV----RDSVRAMPDPDDMALFEHIYADGHPLVDEERAQ 369 Query 359 L 359 Sbjct 370 F 370 >gi|51891549|ref|YP_074240.1| pyruvate dehydrogenase E1 alpha subunit [Symbiobacterium thermophilum IAM 14863] gi|51855238|dbj|BAD39396.1| pyruvate dehydrogenase E1 alpha subunit [Symbiobacterium thermophilum IAM 14863] Length=368 Score = 306 bits (785), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 160/330 (49%), Positives = 207/330 (63%), Gaps = 1/330 (0%) Query 39 LPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCRGQEAAQVGAAACLR-KTDWLF 97 L + L+ +Y MV R D +NLQRQG + + P GQEA+QVG+A LR DW+F Sbjct 34 LSVDQLKDVYRKMVYLRVFDQRCLNLQRQGRMGTFAPFSGQEASQVGSAYLLRPDRDWIF 93 Query 98 PQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQ 157 P YR+ G V G+P ++ + G G P+S+PI TQ LHAVGAA A + Sbjct 94 PTYRDHGAMHVMGVPLVNILRYFMGDEQGSHAPQGVNAFPISIPIATQLLHAVGAAWAGR 153 Query 158 RLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSI 217 ED+V V + GDG TS GD HEALNFAAVF P +F++QNN++AIS P SRQ P+I Sbjct 154 IKGEDTVAVGYAGDGGTSPGDFHEALNFAAVFNVPVIFFIQNNRYAISTPNSRQFKTPTI 213 Query 218 AHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTR 277 A +A+GY + G+RVDG DVLA AVM EA RAR+G GPTL+E+VT+R GPHTT+DDP R Sbjct 214 AQRALGYDIAGVRVDGQDVLAVLAVMHEAIERARSGGGPTLVESVTFRYGPHTTSDDPKR 273 Query 278 YRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAKHVRSELRDAVFDAPDFDV 337 YRSQEE++ W DPI R R YL QG WS +E + A+ + P V Sbjct 274 YRSQEELEEWQARDPIERLRLYLVSQGQWSDSDDEALWTAAREQVAAAVAEAEAMPRPSV 333 Query 338 DEVFTTVYAEITPGLQAQREQLRAELARTD 367 D++F +YAE TP L Q+E L+A LA+ + Sbjct 334 DDLFDYLYAEPTPNLVRQKEYLKAYLAKKE 363 >gi|335430409|ref|ZP_08557303.1| pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit [Haloplasma contractile SSD-17B] gi|334888176|gb|EGM26480.1| pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit [Haloplasma contractile SSD-17B] Length=363 Score = 306 bits (784), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 153/344 (45%), Positives = 215/344 (63%), Gaps = 1/344 (0%) Query 20 VQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELALYTPCRGQ 79 +Q++ +G E+ ++P++ L +Y+ M++ R DT+ + QRQG + Y P +GQ Sbjct 16 LQILDKEGNIVDEKLV-PNIPDDQLVSMYKTMLLGRIADTKALQYQRQGRMLTYAPNKGQ 74 Query 80 EAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTTKCCAPMS 139 EAAQVG+ A ++DWL P +REL +L +G +V + W G G P+S Sbjct 75 EAAQVGSVAATEQSDWLVPAFRELSAWLHKGWTLENVYLYWYGNERGSEFPEDVKILPVS 134 Query 140 VPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTPCVFYVQN 199 VPIG+Q HAVG MA+ +D V +A++GDG TS G+ HEALNF+ VF TP V +QN Sbjct 135 VPIGSQLNHAVGLGMASNIQGKDEVVLAYVGDGGTSHGEFHEALNFSGVFNTPTVIVIQN 194 Query 200 NQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARAGDGPTLI 259 NQWAISMP ++QT + ++A KA YG+PGI+VDGNDVLA YA EA RAR G+GPTLI Sbjct 195 NQWAISMPTTKQTKSQTLAQKAKAYGIPGIQVDGNDVLAVYAATKEAVKRARNGEGPTLI 254 Query 260 EAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEEQVTARAK 319 EAVTYRLGPHTT+DDPT YR EEV+ W+ DP+ R++ YL D+GLWS+ +E Sbjct 255 EAVTYRLGPHTTSDDPTIYRKDEEVEEWSLKDPLTRFQKYLIDKGLWSKEQDENQREEYN 314 Query 320 HVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAEL 363 ++ V + ++++F Y E+ L+ Q E + L Sbjct 315 DFVNKTFKKVEGSGLVPLEDIFDYHYEEMPSQLKEQYENYKRYL 358 >gi|260907141|ref|ZP_05915463.1| pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit [Brevibacterium linens BL2] Length=368 Score = 305 bits (782), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 166/352 (48%), Positives = 211/352 (60%), Gaps = 7/352 (1%) Query 17 LEPVQLVGPDG----TPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 L+P+ +G DG TPT R D L LY MV+ R + + +L RQG LA Sbjct 15 LQPISFIGADGRLTDTPTEGLRIPSD---AALTGLYRQMVLVRRFEAQVTHLTRQGRLAT 71 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 Y GQEAA+VGA L DWLFP YR+ L RG+P + A+RG WH G Sbjct 72 YPSAAGQEAAEVGATTALAPNDWLFPTYRDSAALLTRGVPVAEILAAFRGDWHCGFDPRE 131 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 +P + P+ TQTLHA G AMAA+ ED+ T+ FLGDGA+SEGD HEA NFA+V+ TP Sbjct 132 YHASPAATPLATQTLHATGFAMAAKLKGEDAATLTFLGDGASSEGDTHEAFNFASVWQTP 191 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 VF +QNNQ+AIS P+ QT A +A +A GYGMPG+RVDGNDV A +A +A A R R Sbjct 192 TVFVLQNNQYAISTPLREQTNATMLADRAAGYGMPGLRVDGNDVAAVFAAVAAALERGRN 251 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 GDGPTLIE +TYR+ HT +DDPT+YR EEV+ W DPI R YL+ G Sbjct 252 GDGPTLIECLTYRMESHTNSDDPTKYRDSEEVEHWKQFDPIDRLEKYLRTTGALDDSTVA 311 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELA 364 +V A+ + + +RDA+ + D E+F VYA L Q++ L AELA Sbjct 312 EVAEAAETLAASVRDAMNQEAEVDPRELFAHVYATPRTALAEQQQVLEAELA 363 >gi|220913649|ref|YP_002488958.1| pyruvate dehydrogenase [Arthrobacter chlorophenolicus A6] gi|219860527|gb|ACL40869.1| Pyruvate dehydrogenase (acetyl-transferring) [Arthrobacter chlorophenolicus A6] Length=409 Score = 305 bits (782), Expect = 6e-81, Method: Compositional matrix adjust. Identities = 165/353 (47%), Positives = 215/353 (61%), Gaps = 7/353 (1%) Query 20 VQLVGPDG------TPTAERRYHRDLP-EETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 +Q+V P+G AE + +P + L YE +VV R ++ + L RQG +A+ Sbjct 44 IQMVDPEGRLKDKGEQGAEPGHEYPVPGDAELLAAYEQLVVGRRVNDQNSALVRQGRMAV 103 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 Y GQEA QV AA CL DW+FP YR+ + RG+ P V +RG WHGG Sbjct 104 YPSSHGQEACQVAAALCLGDGDWMFPTYRDAVAVMTRGVDPVQVMTIFRGDWHGGYDPLQ 163 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 S P+ TQ LHAVG A AA+ ED+V +A GDGATSEGD HEALNFAAVF P Sbjct 164 YKVGIQSTPLTTQLLHAVGVAHAAKLRGEDTVVLAMCGDGATSEGDFHEALNFAAVFHLP 223 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 +F+VQNN++AIS+P++ Q+ APS+AHKA+GYGM G RVDGNDV+A AV+ A A R Sbjct 224 VIFFVQNNKYAISVPLAHQSVAPSLAHKAVGYGMAGERVDGNDVVALLAVLDRAVALCRD 283 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GP L+EA TYR+ HT ADD TRYR EV W DP+ R RTYL QG+ E Sbjct 284 GSGPLLVEANTYRMQAHTNADDDTRYRESAEVAEWRAKDPVNRMRTYLTGQGILDDDGEA 343 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELAR 365 ++ A+A+ V ++LR+ + + D ++F V+A TP L+ Q L ELAR Sbjct 344 RIRAKAESVAAQLREGLSEDVPVDPQDLFRHVFAVQTPQLKEQSAFLADELAR 396 >gi|345000793|ref|YP_004803647.1| pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha [Streptomyces sp. SirexAA-E] gi|344316419|gb|AEN11107.1| pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit [Streptomyces sp. SirexAA-E] Length=382 Score = 305 bits (781), Expect = 8e-81, Method: Compositional matrix adjust. Identities = 170/363 (47%), Positives = 216/363 (60%), Gaps = 11/363 (3%) Query 5 SRRPSGMLMSVDLEP--VQLVGPDGTPTAERRYHRDLPEETLRWLYEMMVVTRELDTEFV 62 S+R S EP VQL+ P+G Y DL + LR LY MV+TR D E Sbjct 15 SKRTSAAKTPQKSEPQLVQLLTPEGERVEHPDYTIDLSGDELRGLYRDMVLTRRFDAEAT 74 Query 63 NLQRQGELALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRG 122 LQRQGEL L+ GQEAAQ+G+ LR D++FP YRE GV RG+ P ++ +RG Sbjct 75 ALQRQGELGLWASLLGQEAAQIGSGRALRDDDYVFPTYREHGVAWCRGVDPTNLLGMFRG 134 Query 123 TWHGGLQFTTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEA 182 HGG + ++ IG+QTLHA G AM + DS +A+ GDGA+S+GDV E+ Sbjct 135 VNHGGWDPNSNNFHLYTIVIGSQTLHATGYAMGVAKDGADSAVIAYFGDGASSQGDVAES 194 Query 183 LNFAAVFTTPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAV 242 F+AV+ P VF+ QNNQWAIS P RQT P + +A GYG PG+RVDGNDVLAC AV Sbjct 195 FTFSAVYNAPVVFFCQNNQWAISEPTERQTRVP-LYQRAQGYGFPGVRVDGNDVLACLAV 253 Query 243 MAEAAARARAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQD 302 A RAR G+GPTL+EA TYR+G HTT+DDPT+YR+ EE W DPI R RTYL+ Sbjct 254 TRSALERARRGEGPTLVEAFTYRMGAHTTSDDPTKYRADEERAAWEARDPILRLRTYLEK 313 Query 303 QGL----WSQRLEEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQ 358 Q L + L+E+ A K V R+AV PD D +F YA+ +P + +R Q Sbjct 314 QDLADAAYFTALDEESEALGKRV----REAVRAMPDPDRLAIFDHAYADGSPLVDEERAQ 369 Query 359 LRA 361 A Sbjct 370 FAA 372 >gi|325673585|ref|ZP_08153276.1| pyruvate dehydrogenase complex E1 component alpha subunit [Rhodococcus equi ATCC 33707] gi|325555606|gb|EGD25277.1| pyruvate dehydrogenase complex E1 component alpha subunit [Rhodococcus equi ATCC 33707] Length=365 Score = 305 bits (780), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 169/353 (48%), Positives = 213/353 (61%), Gaps = 14/353 (3%) Query 19 PVQLVGPDGTPTAERRYHR--------DLPEETLRWLYEMMVVTRELDTEFVNLQRQGEL 70 PVQLV PDG +R HR D+ E LR LYE +VV+R +DTE LQRQG+L Sbjct 8 PVQLVQPDG-----QRVHRPDYAALVSDVEPEQLRALYEDLVVSRRIDTEATALQRQGQL 62 Query 71 ALYTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQF 130 ++ P GQEAAQVG+A L + D++F YRE V RG+ P + WRG H G Sbjct 63 GIWAPLLGQEAAQVGSARALERDDYIFTSYREHAVAYCRGVDPELMTRMWRGCAHSGWDP 122 Query 131 TTKCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFT 190 T ++ +G Q LHA G A+ A + TV + GDGATS+GD+ EAL FAA Sbjct 123 ATVNMTNPAIVVGAQGLHATGYALGAHLDGAEIATVVYFGDGATSQGDLSEALGFAASLA 182 Query 191 TPCVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARA 250 P VF+ QNNQWAIS PV Q+ P IA +A G+GMP ++VDGNDVLA AV EAA RA Sbjct 183 APVVFFCQNNQWAISEPVHLQSPTP-IAARAAGHGMPAVQVDGNDVLAVLAVTREAARRA 241 Query 251 RAGDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRL 310 R G GP+ +EAVTYR+GPHTT+DDPTRYR+ E + W DPI R R L+ +GL+ Sbjct 242 RDGGGPSFVEAVTYRMGPHTTSDDPTRYRTAAESELWRARDPIDRMRRLLEREGLFDAEF 301 Query 311 EEQVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAEL 363 + +V RA V + LR +APD DE+F VYA P + +R RA L Sbjct 302 DARVQGRADDVAARLRAGALEAPDPGPDELFEHVYAAEHPLIDEERAAYRAYL 354 >gi|184201771|ref|YP_001855978.1| branched-chain alpha-keto acid dehydrogenase E1 alpha subunit [Kocuria rhizophila DC2201] gi|183582001|dbj|BAG30472.1| branched-chain alpha-keto acid dehydrogenase E1 alpha subunit [Kocuria rhizophila DC2201] Length=400 Score = 304 bits (779), Expect = 1e-80, Method: Compositional matrix adjust. Identities = 161/355 (46%), Positives = 215/355 (61%), Gaps = 7/355 (1%) Query 20 VQLVGPDGTPTAERRYHRD------LPE-ETLRWLYEMMVVTRELDTEFVNLQRQGELAL 72 ++L+ PDGT E ++ +P+ E L YE +VV R ++ + + L RQG +A+ Sbjct 45 IRLLNPDGTAVPESEQGQEPGHEYPMPDTERLLNAYEKLVVGRRINDQNMALVRQGRMAV 104 Query 73 YTPCRGQEAAQVGAAACLRKTDWLFPQYRELGVYLVRGIPPGHVGVAWRGTWHGGLQFTT 132 Y GQEA QV AA CL DWLFP YR+ + RG+ P V +RG WHGG Sbjct 105 YPSSHGQEACQVAAALCLEDDDWLFPTYRDSVAVMSRGVDPLEVMSTYRGDWHGGYDPKK 164 Query 133 KCCAPMSVPIGTQTLHAVGAAMAAQRLDEDSVTVAFLGDGATSEGDVHEALNFAAVFTTP 192 + + P+ TQ LHAVG A AA+ E++VT+A GDGATSEGD HEALNFAAVF P Sbjct 165 YKVSIQATPLTTQLLHAVGVAHAAKLRGENTVTLAMCGDGATSEGDFHEALNFAAVFQLP 224 Query 193 CVFYVQNNQWAISMPVSRQTAAPSIAHKAIGYGMPGIRVDGNDVLACYAVMAEAAARARA 252 +F VQNN +AIS+P+S QT APS+AHK +GYGM RVDGND+ A +V+ R Sbjct 225 VLFLVQNNGYAISVPLSSQTRAPSLAHKGVGYGMASERVDGNDLAAMLSVLGRGIELCRQ 284 Query 253 GDGPTLIEAVTYRLGPHTTADDPTRYRSQEEVDRWATLDPIPRYRTYLQDQGLWSQRLEE 312 G GP L+EA+TYR+ HT ADD TRYR ++EV W DPI R + YL+ QG + Sbjct 285 GGGPLLVEAMTYRMQAHTNADDDTRYRERDEVSEWVAKDPITRMQRYLEGQGALDEDATG 344 Query 313 QVTARAKHVRSELRDAVFDAPDFDVDEVFTTVYAEITPGLQAQREQLRAELARTD 367 +++ A+ + LR+A+ PD D ++F VY E T L+ Q QL EL+R + Sbjct 345 KISGHAEAMAKRLREAMSSKPDLDPQDLFRFVYHEPTTQLREQGAQLADELSREE 399 Lambda K H 0.320 0.134 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 694383994300 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40