BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2505c Length=547 Score E Sequences producing significant alignments: (Bits) Value gi|15609642|ref|NP_217021.1| AMP-binding domain protein [Mycobac... 1115 0.0 gi|289448150|ref|ZP_06437894.1| fatty-acid-CoA ligase fadD35 [My... 1114 0.0 gi|289746287|ref|ZP_06505665.1| substrate-CoA ligase [Mycobacter... 1113 0.0 gi|121638387|ref|YP_978611.1| AMP-binding domain protein [Mycoba... 1113 0.0 gi|240171587|ref|ZP_04750246.1| acyl-CoA synthetase [Mycobacteri... 901 0.0 gi|183983827|ref|YP_001852118.1| fatty-acid-CoA ligase FadD35 [M... 887 0.0 gi|333990040|ref|YP_004522654.1| fatty-acid-CoA ligase [Mycobact... 758 0.0 gi|319950960|ref|ZP_08024832.1| AMP-binding domain protein [Diet... 751 0.0 gi|343927183|ref|ZP_08766662.1| putative fatty-acid--CoA ligase ... 742 0.0 gi|302538259|ref|ZP_07290601.1| cyclohexanecarboxylate-CoA ligas... 733 0.0 gi|302530557|ref|ZP_07282899.1| dicarboxylate-CoA ligase PimA [S... 733 0.0 gi|257057367|ref|YP_003135199.1| AMP-binding domain-containing p... 731 0.0 gi|325675420|ref|ZP_08155104.1| substrate-CoA ligase [Rhodococcu... 724 0.0 gi|312140942|ref|YP_004008278.1| acyl-CoA ligase/synthetase [Rho... 724 0.0 gi|300790301|ref|YP_003770592.1| fatty-acyl-CoA synthase [Amycol... 724 0.0 gi|184201926|ref|YP_001856133.1| putative fatty-acid--CoA ligase... 723 0.0 gi|284989388|ref|YP_003407942.1| AMP-dependent synthetase and li... 720 0.0 gi|111023051|ref|YP_706023.1| AMP-binding domain protein [Rhodoc... 717 0.0 gi|262201331|ref|YP_003272539.1| AMP-dependent synthetase and li... 716 0.0 gi|333922026|ref|YP_004495607.1| Substrate-CoA ligase [Amycolici... 713 0.0 gi|311894125|dbj|BAJ26533.1| putative long-chain fatty-acid--CoA... 711 0.0 gi|134097188|ref|YP_001102849.1| AMP-binding domain protein [Sac... 710 0.0 gi|254385476|ref|ZP_05000803.1| acyl-CoA synthetase [Streptomyce... 710 0.0 gi|331699394|ref|YP_004335633.1| Long-chain-fatty-acid--CoA liga... 708 0.0 gi|300783387|ref|YP_003763678.1| fatty-acyl-CoA synthase [Amycol... 708 0.0 gi|296270056|ref|YP_003652688.1| AMP-dependent synthetase and li... 706 0.0 gi|296140997|ref|YP_003648240.1| AMP-dependent synthetase and li... 706 0.0 gi|226305307|ref|YP_002765265.1| fatty-acid--CoA ligase [Rhodoco... 703 0.0 gi|302541757|ref|ZP_07294099.1| substrate-CoA ligase [Streptomyc... 702 0.0 gi|324997477|ref|ZP_08118589.1| AMP-binding domain protein [Pseu... 702 0.0 gi|326383718|ref|ZP_08205403.1| AMP-dependent synthetase and lig... 699 0.0 gi|226365555|ref|YP_002783338.1| AMP-binding domain protein [Rho... 698 0.0 gi|118467988|ref|YP_889882.1| AMP-binding domain protein [Mycoba... 693 0.0 gi|317123519|ref|YP_004097631.1| AMP-dependent synthetase and li... 689 0.0 gi|297191141|ref|ZP_06908539.1| acyl-CoA synthetase [Streptomyce... 689 0.0 gi|297156367|gb|ADI06079.1| AMP-binding domain protein [Streptom... 688 0.0 gi|258654979|ref|YP_003204135.1| AMP-binding domain-containing p... 686 0.0 gi|337768740|emb|CCB77453.1| Acyl-CoA synthetase family member 2... 682 0.0 gi|297203377|ref|ZP_06920774.1| dicarboxylate-CoA ligase PimA [S... 682 0.0 gi|291436418|ref|ZP_06575808.1| acyl-CoA synthetase [Streptomyce... 680 0.0 gi|315024178|gb|ADT71659.1| putative acyl-CoA synthetase [Mycoba... 677 0.0 gi|294632131|ref|ZP_06710691.1| conserved hypothetical protein [... 676 0.0 gi|229492698|ref|ZP_04386499.1| acyl-CoA synthetase family membe... 675 0.0 gi|290956371|ref|YP_003487553.1| long-chain-fatty-acid-CoA ligas... 675 0.0 gi|328886125|emb|CCA59364.1| acetoacetyl-CoA synthetase or Long-... 675 0.0 gi|345010053|ref|YP_004812407.1| AMP-dependent synthetase and li... 675 0.0 gi|326331582|ref|ZP_08197872.1| substrate--CoA ligase [Nocardioi... 675 0.0 gi|271966242|ref|YP_003340438.1| AMP-dependent synthetase and li... 675 0.0 gi|302557512|ref|ZP_07309854.1| substrate-CoA ligase [Streptomyc... 674 0.0 gi|302555107|ref|ZP_07307449.1| dicarboxylate-CoA ligase PimA [S... 672 0.0 >gi|15609642|ref|NP_217021.1| AMP-binding domain protein [Mycobacterium tuberculosis H37Rv] gi|15842033|ref|NP_337070.1| AMP-binding domain protein [Mycobacterium tuberculosis CDC1551] gi|31793685|ref|NP_856178.1| AMP-binding domain protein [Mycobacterium bovis AF2122/97] 71 more sequence titles Length=547 Score = 1115 bits (2884), Expect = 0.0, Method: Compositional matrix adjust. Identities = 546/547 (99%), Positives = 547/547 (100%), Gaps = 0/547 (0%) Query 1 VAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL 60 +AAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL Sbjct 1 MAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL 60 Query 61 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA 120 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA Sbjct 61 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA 120 Query 121 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ 180 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ Sbjct 121 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ 180 Query 181 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH 240 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH Sbjct 181 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH 240 Query 241 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD 300 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD Sbjct 241 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD 300 Query 301 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG 360 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG Sbjct 301 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG 360 Query 361 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT 420 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT Sbjct 361 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT 420 Query 421 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE 480 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE Sbjct 421 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE 480 Query 481 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL Sbjct 481 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 Query 541 EYLRGQQ 547 EYLRGQQ Sbjct 541 EYLRGQQ 547 >gi|289448150|ref|ZP_06437894.1| fatty-acid-CoA ligase fadD35 [Mycobacterium tuberculosis CPHL_A] gi|289421108|gb|EFD18309.1| fatty-acid-CoA ligase fadD35 [Mycobacterium tuberculosis CPHL_A] Length=547 Score = 1114 bits (2882), Expect = 0.0, Method: Compositional matrix adjust. Identities = 545/547 (99%), Positives = 546/547 (99%), Gaps = 0/547 (0%) Query 1 VAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL 60 +AAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL Sbjct 1 MAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL 60 Query 61 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA 120 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA Sbjct 61 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA 120 Query 121 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ 180 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ Sbjct 121 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ 180 Query 181 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH 240 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH Sbjct 181 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH 240 Query 241 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD 300 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYG PTMFIAELGLPDFTD Sbjct 241 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGAPTMFIAELGLPDFTD 300 Query 301 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG 360 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG Sbjct 301 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG 360 Query 361 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT 420 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT Sbjct 361 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT 420 Query 421 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE 480 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE Sbjct 421 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE 480 Query 481 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL Sbjct 481 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 Query 541 EYLRGQQ 547 EYLRGQQ Sbjct 541 EYLRGQQ 547 >gi|289746287|ref|ZP_06505665.1| substrate-CoA ligase [Mycobacterium tuberculosis 02_1987] gi|289686815|gb|EFD54303.1| substrate-CoA ligase [Mycobacterium tuberculosis 02_1987] Length=547 Score = 1113 bits (2879), Expect = 0.0, Method: Compositional matrix adjust. Identities = 545/547 (99%), Positives = 546/547 (99%), Gaps = 0/547 (0%) Query 1 VAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL 60 +AAAEVVD NRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL Sbjct 1 MAAAEVVDSNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL 60 Query 61 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA 120 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA Sbjct 61 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA 120 Query 121 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ 180 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ Sbjct 121 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ 180 Query 181 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH 240 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH Sbjct 181 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH 240 Query 241 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD 300 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD Sbjct 241 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD 300 Query 301 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG 360 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG Sbjct 301 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG 360 Query 361 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT 420 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT Sbjct 361 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT 420 Query 421 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE 480 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE Sbjct 421 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE 480 Query 481 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL Sbjct 481 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 Query 541 EYLRGQQ 547 EYLRGQQ Sbjct 541 EYLRGQQ 547 >gi|121638387|ref|YP_978611.1| AMP-binding domain protein [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224990881|ref|YP_002645568.1| acyl-CoA synthetase [Mycobacterium bovis BCG str. Tokyo 172] gi|121494035|emb|CAL72513.1| Probable fatty-acid-CoA ligase fadD35 [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|224773994|dbj|BAH26800.1| acyl-CoA synthetase [Mycobacterium bovis BCG str. Tokyo 172] gi|341602425|emb|CCC65101.1| probable fatty-acid-CoA ligase fadD35 [Mycobacterium bovis BCG str. Moreau RDJ] Length=547 Score = 1113 bits (2879), Expect = 0.0, Method: Compositional matrix adjust. Identities = 545/547 (99%), Positives = 546/547 (99%), Gaps = 0/547 (0%) Query 1 VAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL 60 +AAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL Sbjct 1 MAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL 60 Query 61 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA 120 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA Sbjct 61 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA 120 Query 121 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ 180 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ Sbjct 121 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ 180 Query 181 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH 240 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH Sbjct 181 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH 240 Query 241 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD 300 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD Sbjct 241 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD 300 Query 301 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG 360 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG Sbjct 301 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG 360 Query 361 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT 420 TVGRVGPHLEIKVVDPATGE VPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT Sbjct 361 TVGRVGPHLEIKVVDPATGEAVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT 420 Query 421 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE 480 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE Sbjct 421 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE 480 Query 481 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL Sbjct 481 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 Query 541 EYLRGQQ 547 EYLRGQQ Sbjct 541 EYLRGQQ 547 >gi|240171587|ref|ZP_04750246.1| acyl-CoA synthetase [Mycobacterium kansasii ATCC 12478] Length=547 Score = 901 bits (2329), Expect = 0.0, Method: Compositional matrix adjust. Identities = 430/546 (79%), Positives = 479/546 (88%), Gaps = 0/546 (0%) Query 1 VAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL 60 +AA D + LSY+RGP+ P+LLE+TIG NLA TA+R+G R ALVD A RR+NY+E L Sbjct 1 MAANGAADHSALSYERGPNVPALLETTIGVNLAETASRHGQRHALVDAHAGRRWNYAEFL 60 Query 61 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA 120 DV RLATGLVRAGIG GDRVGIWAPNRWEWVLVQYATAEIGAILVT+NPAYR E+ YA Sbjct 61 ADVRRLATGLVRAGIGVGDRVGIWAPNRWEWVLVQYATAEIGAILVTVNPAYRSIELRYA 120 Query 121 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ 180 LRQSGV M+IA + FKDADY A+LAEV P CPDL + + ++SDRWD LAG + DL ALQQ Sbjct 121 LRQSGVCMIIAASGFKDADYRAILAEVAPDCPDLREAVFMDSDRWDELAGTQSDLAALQQ 180 Query 181 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH 240 A+ L GSDPVNIQYTSGTT +PKGVTLSHRNILNNGY VGELL YTA DRICIP PFYH Sbjct 181 IASTLTGSDPVNIQYTSGTTGHPKGVTLSHRNILNNGYFVGELLDYTADDRICIPAPFYH 240 Query 241 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD 300 CFGMV+GNLAATSHGAA+VIPAPGFDPAATLRAVQ ERCTSLYGVPTMFIAELGLPDFTD Sbjct 241 CFGMVLGNLAATSHGAAVVIPAPGFDPAATLRAVQTERCTSLYGVPTMFIAELGLPDFTD 300 Query 301 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG 360 Y+L SLRTGIMAG+ CPVEVMR VI +MHMP +SICYGMTETSPVSTQTR DS++RRVG Sbjct 301 YDLTSLRTGIMAGSTCPVEVMRMVIEQMHMPAISICYGMTETSPVSTQTRTGDSLERRVG 360 Query 361 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT 420 TVGRVGPHLEIKVVDP TGETVPRGV GEFCTRGYSVMAGYWNDP++TAEVID DGWMH+ Sbjct 361 TVGRVGPHLEIKVVDPVTGETVPRGVPGEFCTRGYSVMAGYWNDPERTAEVIDDDGWMHS 420 Query 421 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE 480 GDLA MD GYV+I GRIKD+V+RGGEN+SPREIEE LHTHPD+VD HVIGVPD + GEE Sbjct 421 GDLAAMDACGYVQITGRIKDIVIRGGENVSPREIEEFLHTHPDVVDAHVIGVPDERVGEE 480 Query 481 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 LMAV+KLR+ AP+LTI RL E+C RIARFKIPRY+ IVDEFPMTVTGKVRKVE+RQQA+ Sbjct 481 LMAVIKLRDGAPQLTIARLHEFCADRIARFKIPRYVRIVDEFPMTVTGKVRKVELRQQAI 540 Query 541 EYLRGQ 546 +YL+G+ Sbjct 541 DYLQGR 546 >gi|183983827|ref|YP_001852118.1| fatty-acid-CoA ligase FadD35 [Mycobacterium marinum M] gi|183177153|gb|ACC42263.1| fatty-acid-CoA ligase FadD35 [Mycobacterium marinum M] Length=547 Score = 887 bits (2291), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/547 (79%), Positives = 474/547 (87%), Gaps = 0/547 (0%) Query 1 VAAAEVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELL 60 +A D N+LSYDRGP AP+LLE TIGANLAATA++ R+ALVD+ + RR++Y++LL Sbjct 1 MATTAAADQNQLSYDRGPIAPALLEMTIGANLAATASQCESRDALVDVRSGRRWSYAQLL 60 Query 61 TDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYA 120 TDV +LATGLVRAGIG GDRVGIWAPNRWEWVLVQYATAEIGA+LVTINPAY+ RE+EYA Sbjct 61 TDVRQLATGLVRAGIGRGDRVGIWAPNRWEWVLVQYATAEIGAVLVTINPAYQARELEYA 120 Query 121 LRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQ 180 LRQSGVAMVIA + FK +DYAA+LAEV P CP+L DV L+ D W LAG+ DL ALQ+ Sbjct 121 LRQSGVAMVIAASGFKGSDYAAILAEVAPGCPELHDVAFLDGDGWAKLAGSGADLVALQE 180 Query 181 TAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYH 240 A L DP+NIQYTSGTT +PKGVTLSHRNILNNGYLVGELL YTA+DRICIPVPFYH Sbjct 181 IATTLSADDPINIQYTSGTTGFPKGVTLSHRNILNNGYLVGELLEYTAEDRICIPVPFYH 240 Query 241 CFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTD 300 CFGMVMGNLAATSHGA MVIPAPGFDPAATLRAVQ ERCTSLYGVPTMFIAELGL DF Sbjct 241 CFGMVMGNLAATSHGACMVIPAPGFDPAATLRAVQAERCTSLYGVPTMFIAELGLADFAT 300 Query 301 YELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVG 360 Y+L SLRTGIMAG+ CPVEVMRKVI +MHM G+SICYGMTETSPV+TQTR++DS+ RRV Sbjct 301 YDLSSLRTGIMAGSTCPVEVMRKVIDQMHMAGISICYGMTETSPVATQTRSNDSLQRRVT 360 Query 361 TVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHT 420 TVGRVGPHLEIKVVDPATG VPRG GEFCTRGYSVM+GYW P++TAEVID +GWMHT Sbjct 361 TVGRVGPHLEIKVVDPATGRIVPRGTAGEFCTRGYSVMSGYWKAPERTAEVIDPEGWMHT 420 Query 421 GDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEE 480 GDLA MD GYV+I GRIKD+VVRGGENISPREIEE LH+HPDIVD HV+GVPD + GEE Sbjct 421 GDLALMDECGYVQITGRIKDIVVRGGENISPREIEEFLHSHPDIVDAHVVGVPDERMGEE 480 Query 481 LMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 LMAVVKLR APELT LREYC G+IA+FKIPRYL +VDEFPMTVTGKVRKVEMRQQA+ Sbjct 481 LMAVVKLRAGAPELTTGLLREYCAGQIAKFKIPRYLRLVDEFPMTVTGKVRKVEMRQQAI 540 Query 541 EYLRGQQ 547 EYLRGQ Sbjct 541 EYLRGQH 547 >gi|333990040|ref|YP_004522654.1| fatty-acid-CoA ligase [Mycobacterium sp. JDM601] gi|333486008|gb|AEF35400.1| fatty-acid-CoA ligase FadD35 [Mycobacterium sp. JDM601] Length=511 Score = 758 bits (1957), Expect = 0.0, Method: Compositional matrix adjust. Identities = 363/504 (73%), Positives = 417/504 (83%), Gaps = 0/504 (0%) Query 42 REALVDMVARRRFNYSELLTDVHRLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEI 101 R+AL+D+ ARRR+NY+EL DV RLATGL++AGI GDRVGIWAPN EWVL QYATAEI Sbjct 7 RDALIDLPARRRWNYAELWRDVRRLATGLLQAGISAGDRVGIWAPNCAEWVLTQYATAEI 66 Query 102 GAILVTINPAYRVREVEYALRQSGVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLE 161 GA+LVTINPAYR E+ YAL QSG+AMVI+ + FK +DY A+L EV P CP L + + ++ Sbjct 67 GAVLVTINPAYRSHELAYALNQSGLAMVISASRFKTSDYVALLREVAPACPGLREAVFID 126 Query 162 SDRWDALAGAEPDLPALQQTAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVG 221 S RW LAG D AL A L +DP+NIQYTSGTT YPKGVTLSHRNILNNGYLVG Sbjct 127 SARWRELAGTPVDTVALAHAARPLRATDPINIQYTSGTTGYPKGVTLSHRNILNNGYLVG 186 Query 222 ELLGYTAQDRICIPVPFYHCFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTS 281 +LLGYT +DRIC+PVP YHCFG+VMGNLAATSHGAA+++P PGFDPAATLRAVQ+E CTS Sbjct 187 DLLGYTHRDRICLPVPLYHCFGLVMGNLAATSHGAAIILPGPGFDPAATLRAVQEEACTS 246 Query 282 LYGVPTMFIAELGLPDFTDYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTE 341 LYGVPTMFIAELGLPDF DY+L SLRTGIMAG+ CP +VMR+VI MHM ++ICYGMTE Sbjct 247 LYGVPTMFIAELGLPDFADYDLTSLRTGIMAGSPCPAQVMRRVIDDMHMTEIAICYGMTE 306 Query 342 TSPVSTQTRADDSVDRRVGTVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGY 401 TSPVSTQTR+ DS+ +RV TVGRVGPHLEIK++DPATG VPRG VGE CTRGYSVM GY Sbjct 307 TSPVSTQTRSGDSLTQRVETVGRVGPHLEIKMIDPATGHPVPRGQVGELCTRGYSVMTGY 366 Query 402 WNDPQKTAEVIDADGWMHTGDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTH 461 WNDP K+ IDA+GWMH+GDLA MD GYVRI GRIKD+V+RGGENI PREIEE LHTH Sbjct 367 WNDPAKSEAAIDAEGWMHSGDLAVMDDDGYVRITGRIKDMVIRGGENIYPREIEEFLHTH 426 Query 462 PDIVDGHVIGVPDAKYGEELMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDE 521 PDI+D VIGVPD YGEELMAVV LR+ A LT+ERLRE+C GR+A FK+PRYL +V E Sbjct 427 PDILDAQVIGVPDEIYGEELMAVVMLRDGAGPLTVERLREFCAGRLAHFKVPRYLRVVAE 486 Query 522 FPMTVTGKVRKVEMRQQALEYLRG 545 FPMT TGKVRK E+R+Q +E L G Sbjct 487 FPMTATGKVRKDEVRRQVIEQLGG 510 >gi|319950960|ref|ZP_08024832.1| AMP-binding domain protein [Dietzia cinnamea P4] gi|319435382|gb|EFV90630.1| AMP-binding domain protein [Dietzia cinnamea P4] Length=549 Score = 751 bits (1939), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/537 (67%), Positives = 421/537 (79%), Gaps = 1/537 (0%) Query 7 VDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRL 66 +DP LS+ RG + LL TI NLAAT +G R+ALVD+ A RR+ YSE L DV RL Sbjct 11 LDP-ALSHTRGETDVPLLTQTIPENLAATVEEFGDRDALVDVQAGRRWTYSEFLADVRRL 69 Query 67 ATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGV 126 A+GL R GI GDRVGIW+PNRWEWV+VQYATAEIGA+LV INP+YRV E+E+ L Q+ + Sbjct 70 ASGLHRLGIRAGDRVGIWSPNRWEWVMVQYATAEIGAVLVNINPSYRVHELEFVLGQAAI 129 Query 127 AMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQTAARLD 186 VIA FKD+DY MLA+V P CPDL V+L + W+++ D L + A L Sbjct 130 KAVIAAPQFKDSDYTGMLAQVQPNCPDLELVVLFGDEEWESMVSGPTDADVLAEIRAGLT 189 Query 187 GSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVM 246 DP+NIQYTSGTT +PKG TLSH NILNNGY VGEL+ Y+ DR+CIPVPFYHCFGMVM Sbjct 190 NHDPINIQYTSGTTGFPKGATLSHSNILNNGYFVGELINYSEVDRVCIPVPFYHCFGMVM 249 Query 247 GNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSL 306 GNLA T+HG+ MVIPAP FDP A+L+AV+ E+CTSLYGVPTMFIAEL L DF Y+L +L Sbjct 250 GNLACTTHGSCMVIPAPAFDPVASLKAVEQEKCTSLYGVPTMFIAELALEDFDSYDLSTL 309 Query 307 RTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVG 366 RTGIMAG+ CP MR+VI RM+M VSICYGMTETSPVSTQTRADDS+DRRV TVGRVG Sbjct 310 RTGIMAGSPCPEATMRQVIDRMNMEEVSICYGMTETSPVSTQTRADDSLDRRVATVGRVG 369 Query 367 PHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEM 426 PHLEIK++DP+TGET+PRG GEFCTRGYSVM GYW P KTAE ID GWMHTGD+ EM Sbjct 370 PHLEIKIIDPSTGETLPRGEAGEFCTRGYSVMLGYWEQPDKTAEAIDEAGWMHTGDIGEM 429 Query 427 DPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVK 486 D GYV+I GRIKD+V+RGGENI PRE+EE L+THPDI+D VIGVPD KYGEELMA V+ Sbjct 430 DADGYVKITGRIKDMVIRGGENIYPREVEEFLYTHPDILDAQVIGVPDPKYGEELMAWVR 489 Query 487 LRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 L+ +LT + +RE+ G++AR KIP+Y+ +VDEFPMTVTGKVRKV+MR+ A+E L Sbjct 490 LKPGRDDLTADEVREFATGKLARHKIPKYVHVVDEFPMTVTGKVRKVDMRKTAVEIL 546 >gi|343927183|ref|ZP_08766662.1| putative fatty-acid--CoA ligase [Gordonia alkanivorans NBRC 16433] gi|343762921|dbj|GAA13588.1| putative fatty-acid--CoA ligase [Gordonia alkanivorans NBRC 16433] Length=551 Score = 742 bits (1915), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/544 (68%), Positives = 420/544 (78%), Gaps = 9/544 (1%) Query 10 NRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATG 69 L++ GP +P+LL TIG LA T +Y AL+D A R++ Y+E DV LA G Sbjct 8 QNLAHTHGPQSPALLTDTIGVTLARTVEKYAGHVALIDAGAGRQWTYTEFHRDVRALAAG 67 Query 70 LVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMV 129 L+R G+ GDRVG+WAPNR+EWVLVQYATAEIGAILV +NPAYR EVEYALRQSG ++V Sbjct 68 LLRLGVKRGDRVGLWAPNRFEWVLVQYATAEIGAILVNLNPAYRQNEVEYALRQSGTSVV 127 Query 130 IAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPD--LPALQQTAARLDG 187 +A FKD+ YA+MLAE P CPDL +V+ ES W L D L + + AA L Sbjct 128 LAAERFKDSGYASMLAEAHPHCPDLREVVTFESAAWTELTATPTDEELARVAEIAASLSA 187 Query 188 SDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMG 247 DP+NIQYTSGTT +PKG TLSHRNI NNGYLVGELL YTA DRIC+PVPFYHCFGMVMG Sbjct 188 DDPINIQYTSGTTGFPKGATLSHRNIGNNGYLVGELLDYTADDRICLPVPFYHCFGMVMG 247 Query 248 NLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGL----PDFTDYEL 303 NLAATSHGAAMVIP P FDP ATL AV + RCTSLYGVPTMFIAEL L PD +L Sbjct 248 NLAATSHGAAMVIPGPAFDPKATLDAVAEHRCTSLYGVPTMFIAELALLDAAPDGYAPDL 307 Query 304 GSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVG 363 SLRTGIMAG+ CP +VMR+V+ RMHM VSICYGMTETSPVSTQTR DD ++ RV TVG Sbjct 308 SSLRTGIMAGSPCPEQVMRQVVDRMHMSEVSICYGMTETSPVSTQTRVDDPLELRVTTVG 367 Query 364 RVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDL 423 +VGPHLEIK+V P TGET+ R GE CTRGYSVM GYWNDP+KTAE IDADGWMHTGDL Sbjct 368 QVGPHLEIKIVAPGTGETLGRNETGELCTRGYSVMTGYWNDPEKTAEAIDADGWMHTGDL 427 Query 424 AEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMA 483 AEMD +GYVRI GRIKD+V+RGGENI PREIEE L+THPDI+D VIGVPD KYGEELMA Sbjct 428 AEMDEAGYVRITGRIKDMVIRGGENIYPREIEEFLYTHPDILDAQVIGVPDEKYGEELMA 487 Query 484 VVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQA---L 540 V+LR+ A +LT E +R + G+IAR KIPRY+ +V EFPMTVTGKVRKV MR++A L Sbjct 488 WVRLRDHATDLTAEDVRAFADGKIARHKIPRYVHVVKEFPMTVTGKVRKVAMREEATHIL 547 Query 541 EYLR 544 E LR Sbjct 548 EDLR 551 >gi|302538259|ref|ZP_07290601.1| cyclohexanecarboxylate-CoA ligase [Streptomyces sp. C] gi|302447154|gb|EFL18970.1| cyclohexanecarboxylate-CoA ligase [Streptomyces sp. C] Length=545 Score = 733 bits (1892), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/533 (69%), Positives = 417/533 (79%), Gaps = 2/533 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 S+ G + LL+ TIG NL T R+ R+ALVD+ A RR+ Y+EL DV LA GL+ Sbjct 10 SHASGSTGVPLLDETIGDNLDRTVRRFPDRDALVDVAAGRRWTYAELAADVDVLALGLLD 69 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 GI GDRVGIWAPNR EW LVQYATA+IGAILVT+NPAYR E+EY L QSG+ +++A Sbjct 70 LGITAGDRVGIWAPNRAEWTLVQYATAKIGAILVTVNPAYRSHELEYVLNQSGIRLLVAA 129 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALA--GAEPDLPALQQTAARLDGSDP 190 A FK +DYAAM+ EV PRC DL +LL+ WD+L GA+ D L + AA LD DP Sbjct 130 AGFKGSDYAAMIEEVRPRCADLEFTVLLDGPLWDSLRERGAQGDPADLARAAAALDPGDP 189 Query 191 VNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLA 250 VNIQYTSGTT +PKG TLSHRNILNNG+ VGEL GYT +DR+C+PVPFYHCFGMVMG LA Sbjct 190 VNIQYTSGTTGFPKGATLSHRNILNNGFFVGELCGYTERDRVCVPVPFYHCFGMVMGALA 249 Query 251 ATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGI 310 TSHGAAMVIPAP FDPAATL AV+ E CTSLYGVPTMFIAEL P F Y+L SLRTGI Sbjct 250 CTSHGAAMVIPAPAFDPAATLAAVEAEACTSLYGVPTMFIAELAAPGFDGYDLSSLRTGI 309 Query 311 MAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLE 370 MAG+ CPVEVM +VI RM M VSICYGMTETSPVSTQTR DDSV+RRV TVGRVGPHLE Sbjct 310 MAGSPCPVEVMNEVIERMGMAEVSICYGMTETSPVSTQTRVDDSVERRVSTVGRVGPHLE 369 Query 371 IKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSG 430 +KVVDP TG TVPRG GE CTRGYSVM GYW +PQKTAE +D +GWMHTGDLA MD G Sbjct 370 VKVVDPETGATVPRGTPGELCTRGYSVMLGYWGEPQKTAEAVDGEGWMHTGDLAVMDADG 429 Query 431 YVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRND 490 Y+ I GRIKD+V+RGGEN+ PREIEE LH HPD++D VIGVPDAKYGEELMA V++R Sbjct 430 YLAITGRIKDMVIRGGENLYPREIEEFLHGHPDVLDVQVIGVPDAKYGEELMAWVRMREG 489 Query 491 APELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 A LT E +R YC GR+A FKIPRY+ +VDEFPMTVTGK+RKVEMR+ A L Sbjct 490 AEPLTAETVRAYCSGRLAHFKIPRYVHVVDEFPMTVTGKIRKVEMREAAARLL 542 >gi|302530557|ref|ZP_07282899.1| dicarboxylate-CoA ligase PimA [Streptomyces sp. AA4] gi|302439452|gb|EFL11268.1| dicarboxylate-CoA ligase PimA [Streptomyces sp. AA4] Length=546 Score = 733 bits (1891), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/537 (67%), Positives = 413/537 (77%), Gaps = 2/537 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G S+ LL TIG N T A +G R+ALVD A R+ Y EL +V LA GL+ Sbjct 3 SYASGTSSVPLLGDTIGDNFDRTVAAFGDRDALVDREAGARWTYRELAAEVDTLAHGLLA 62 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 +GIG GDRVGIW+PNR EW +QYATA+IGAILV INPAYR E++Y L Q+G+ +++A Sbjct 63 SGIGKGDRVGIWSPNRAEWTFLQYATAKIGAILVNINPAYRSHELKYVLNQAGIRLLVAA 122 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL--AGAEPDLPALQQTAARLDGSDP 190 FK +DYAAM+ EV P CP L V+LL + W L +G D L Q A L DP Sbjct 123 DKFKTSDYAAMIEEVRPDCPGLEAVVLLGTSSWTDLMESGRGGDPARLAQLQAGLSADDP 182 Query 191 VNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLA 250 +NIQYTSGTT +PKG TLSH NILNNGY VGEL YT +DR+CIPVPFYHCFGMVMGNLA Sbjct 183 INIQYTSGTTGFPKGATLSHHNILNNGYFVGELCNYTEEDRVCIPVPFYHCFGMVMGNLA 242 Query 251 ATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGI 310 TSHGA MVIPAP FDP ATL AV ERCTSLYGVPTMFIAEL P+F ++LGSLRTGI Sbjct 243 CTSHGACMVIPAPAFDPKATLAAVAAERCTSLYGVPTMFIAELNHPEFETFDLGSLRTGI 302 Query 311 MAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLE 370 MAG+ CPVEVM++VI RM M VSICYGMTETSPVSTQTRADDSV+RRV TVGRVGPHLE Sbjct 303 MAGSPCPVEVMKQVIDRMGMTEVSICYGMTETSPVSTQTRADDSVERRVSTVGRVGPHLE 362 Query 371 IKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSG 430 KVVDP TG TVPRG GE CTRGYSVM GYW +P+KTAE IDA WMHTGDLA MD G Sbjct 363 SKVVDPETGLTVPRGTPGELCTRGYSVMLGYWEEPEKTAEAIDAARWMHTGDLAIMDDEG 422 Query 431 YVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRND 490 Y+ I GRIKD+V+RGGENI PREIEE L+THPD++D VIGVPD KYGEELMA +++R Sbjct 423 YLNITGRIKDMVIRGGENIYPREIEEFLYTHPDVLDAQVIGVPDVKYGEELMAWIRMREG 482 Query 491 APELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRGQQ 547 A LT+E +RE+C G++A +KIPRY+ +V+EFPMTVTGKVRKVEMRQQ++ L +Q Sbjct 483 AEPLTVESVREFCQGKLAHYKIPRYIHVVEEFPMTVTGKVRKVEMRQQSVTLLGLEQ 539 >gi|257057367|ref|YP_003135199.1| AMP-binding domain-containing protein [Saccharomonospora viridis DSM 43017] gi|256587239|gb|ACU98372.1| acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II [Saccharomonospora viridis DSM 43017] Length=552 Score = 731 bits (1887), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/533 (67%), Positives = 407/533 (77%), Gaps = 2/533 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G S LL TIG NL TA + R+ALVD + RR+NY E + DV LA GL+ Sbjct 9 SYTSGTSTVPLLGDTIGDNLDRTARTFADRDALVDYASGRRWNYREFVADVDALALGLLY 68 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 G+ GDRVGIWAPN +W L QYATA+IGAILV INPAYR E+EY L Q+G++ +IA Sbjct 69 RGVTKGDRVGIWAPNCPQWTLTQYATAKIGAILVNINPAYREHELEYVLNQAGISTLIAA 128 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL--AGAEPDLPALQQTAARLDGSDP 190 + FK +DYA M+ +V PRCP L DV+ L+ D WD L G + D L + A L DP Sbjct 129 SEFKTSDYAGMIHKVRPRCPSLTDVVFLDGDHWDDLLDTGRKADPERLARAQAALSADDP 188 Query 191 VNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLA 250 +NIQYTSGTT +PKG TLSH NILNNG+ VGEL YT DRIC+PVPFYHCFGMVMGNLA Sbjct 189 INIQYTSGTTGFPKGATLSHHNILNNGFFVGELCRYTEVDRICLPVPFYHCFGMVMGNLA 248 Query 251 ATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGI 310 AT+HGA MVIPAP FDPA TL AVQ ERCTSLYGVPTMFIAEL PDF Y+L SLRTGI Sbjct 249 ATTHGACMVIPAPSFDPAKTLAAVQAERCTSLYGVPTMFIAELAEPDFDSYDLSSLRTGI 308 Query 311 MAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLE 370 MAG+ CPVEVM++VI RM M VSICYGMTETSPVS QTR DDS++RRV TVGRVGPHLE Sbjct 309 MAGSPCPVEVMKQVIERMGMTEVSICYGMTETSPVSMQTRVDDSIERRVSTVGRVGPHLE 368 Query 371 IKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSG 430 K++DP TG TVPRG GE CTRGYSVM GYW P KTAEVID WMHTGDLA MD G Sbjct 369 AKIIDPETGLTVPRGTHGELCTRGYSVMLGYWEQPDKTAEVIDEARWMHTGDLAVMDEDG 428 Query 431 YVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRND 490 YV I GR+KD+V+R GENI PREIEE L+THPDI+D VIGVPD +YGEELMA V++R Sbjct 429 YVNITGRLKDMVIRDGENIYPREIEEFLYTHPDILDAQVIGVPDERYGEELMAWVRMREG 488 Query 491 APELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 A LT E LRE+C G++A +KIPRY+ +VDEFPMTVTGKVRKVEMR++A+E L Sbjct 489 AEPLTAESLREFCTGKLAHYKIPRYVHVVDEFPMTVTGKVRKVEMRKRAVELL 541 >gi|325675420|ref|ZP_08155104.1| substrate-CoA ligase [Rhodococcus equi ATCC 33707] gi|325553391|gb|EGD23069.1| substrate-CoA ligase [Rhodococcus equi ATCC 33707] Length=550 Score = 724 bits (1869), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/536 (66%), Positives = 411/536 (77%), Gaps = 5/536 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G +L TIG N T A +G R+AL+D + RR+ Y EL +V LATGL+ Sbjct 12 SYASGTWDAPMLGDTIGDNFDRTVAAHGDRDALIDRGSGRRWTYRELAREVDALATGLLG 71 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 GI GDRVGIWAPN EW +VQYATA+IGAILV INPAYR E+EY L Q+G+ M+IA Sbjct 72 TGITKGDRVGIWAPNCAEWTMVQYATAKIGAILVNINPAYRSHELEYVLDQAGIRMLIAA 131 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL-----AGAEPDLPALQQTAARLDG 187 +FK +DYAAM+ +V P L V+LL S+RWD L A E D AL + L Sbjct 132 PAFKTSDYAAMIEQVRPERAALEHVLLLGSERWDRLLDDGRAALEADRAALDRAQGALSA 191 Query 188 SDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMG 247 DP+NIQYTSGTT +PKG TLSH NILNNGY VGEL GYT DR+CIPVPFYHCFGMVMG Sbjct 192 DDPINIQYTSGTTGFPKGATLSHHNILNNGYFVGELCGYTEHDRVCIPVPFYHCFGMVMG 251 Query 248 NLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLR 307 NLA TSHGAAMVIP P F+PAATL AVQ ERCTSLYGVPTMFIAEL PDF Y+L LR Sbjct 252 NLACTSHGAAMVIPGPAFEPAATLAAVQAERCTSLYGVPTMFIAELADPDFDSYDLSCLR 311 Query 308 TGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGP 367 TGIMAG+ CPVEVM++VI RM M VSICYGMTETSPVS QTR DDS+D+RV TVGRVGP Sbjct 312 TGIMAGSPCPVEVMKQVIERMGMAEVSICYGMTETSPVSLQTRRDDSIDQRVSTVGRVGP 371 Query 368 HLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMD 427 HLE+K+VDPATG TVPRG GE CTRGYSVM GYWN+P+KT+E ID+ WMHTGD+ MD Sbjct 372 HLEVKIVDPATGLTVPRGEAGELCTRGYSVMLGYWNNPEKTSEAIDSARWMHTGDIGVMD 431 Query 428 PSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKL 487 GYV I GRIKD+V+RGGEN+ PREIEE L+THPDI+D VIGVPDAKYGEELM +++ Sbjct 432 SDGYVAITGRIKDMVIRGGENVYPREIEEFLYTHPDILDAQVIGVPDAKYGEELMVWIRM 491 Query 488 RNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 R A L ++++RE+C GR+A +KIPRY+ +VDEFPMTVTGK+RKVEMR+ +LE + Sbjct 492 REGAQPLDVDKVREFCTGRLAHYKIPRYVHLVDEFPMTVTGKIRKVEMRELSLELI 547 >gi|312140942|ref|YP_004008278.1| acyl-CoA ligase/synthetase [Rhodococcus equi 103S] gi|311890281|emb|CBH49599.1| acyl-CoA ligase/synthetase [Rhodococcus equi 103S] Length=550 Score = 724 bits (1869), Expect = 0.0, Method: Compositional matrix adjust. Identities = 352/536 (66%), Positives = 412/536 (77%), Gaps = 5/536 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G +L TIG N T A +G R+AL+D + RR+ Y EL +V LATGL+ Sbjct 12 SYASGTWDAPMLGDTIGDNFDRTVAAHGDRDALIDRGSGRRWTYRELAREVDALATGLLG 71 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 GI GDRVGIWAPN EW +VQYATA+IGAILV INPAYR E+EY L Q+G+ M+IA Sbjct 72 TGITKGDRVGIWAPNCAEWTMVQYATAKIGAILVNINPAYRSHELEYVLDQAGIRMLIAA 131 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL-----AGAEPDLPALQQTAARLDG 187 +FK +DYAAM+ +V P L V+LL S++WD L A E D AL + L Sbjct 132 PAFKTSDYAAMIEQVRPERAALEHVLLLGSEQWDRLLDDGRAALEADRAALDRAQGALSA 191 Query 188 SDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMG 247 DP+NIQYTSGTT +PKG TLSH NILNNGY VGEL GYT DR+CIPVPFYHCFGMVMG Sbjct 192 DDPINIQYTSGTTGFPKGATLSHHNILNNGYFVGELCGYTEHDRVCIPVPFYHCFGMVMG 251 Query 248 NLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLR 307 NLA TSHGAAMVIP P F+PAATL AVQ ERCTSLYGVPTMFIAEL PDF Y+L SLR Sbjct 252 NLACTSHGAAMVIPGPAFEPAATLAAVQAERCTSLYGVPTMFIAELADPDFDSYDLSSLR 311 Query 308 TGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGP 367 TGIMAG+ CPVEVM++VI RM M VSICYGMTETSPVS QTR DDS+D+RV TVGRVGP Sbjct 312 TGIMAGSPCPVEVMKQVIERMGMAEVSICYGMTETSPVSLQTRRDDSIDQRVSTVGRVGP 371 Query 368 HLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMD 427 HLE+K+VDPATG TVPRG GE CTRGYSVM GYWN+P+KT+E ID+ WMHTGD+ MD Sbjct 372 HLEVKIVDPATGLTVPRGEAGELCTRGYSVMLGYWNNPEKTSEAIDSARWMHTGDIGVMD 431 Query 428 PSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKL 487 GYV I GRIKD+V+RGGEN+ PREIEE L+THPDI+D VIGVPDAKYGEELM +++ Sbjct 432 SDGYVAITGRIKDMVIRGGENVYPREIEEFLYTHPDILDAQVIGVPDAKYGEELMVWIRM 491 Query 488 RNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 R A L ++++RE+C GR+A +KIPRY+ +VDEFPMTVTGK+RKVEMR+ +LE + Sbjct 492 REGAQPLDVDKVREFCTGRLAHYKIPRYVHLVDEFPMTVTGKIRKVEMRELSLELI 547 >gi|300790301|ref|YP_003770592.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32] gi|299799815|gb|ADJ50190.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32] gi|340531982|gb|AEK47187.1| AMP-binding domain protein [Amycolatopsis mediterranei S699] Length=552 Score = 724 bits (1868), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/541 (66%), Positives = 408/541 (76%), Gaps = 2/541 (0%) Query 9 PNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLAT 68 P SY G S LL TIG N T A +G R+ALVD A RR+ Y EL +V LA Sbjct 5 PALPSYASGTSEVPLLGDTIGDNFDRTVAAFGDRDALVDRTAGRRWTYRELAAEVTALAL 64 Query 69 GLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAM 128 GLV GIG GDRVGIW+PNR EW +QYATA+IGAILV INPAYR E+EY L Q+G+ + Sbjct 65 GLVAQGIGKGDRVGIWSPNRAEWTFLQYATAKIGAILVNINPAYRAHELEYVLNQAGIRL 124 Query 129 VIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL--AGAEPDLPALQQTAARLD 186 ++A FK +DY AM EV +C L V++L + W AL AG D L A L Sbjct 125 LVASDKFKTSDYPAMADEVREKCAALEQVVILGGEGWQALLAAGRGGDPAQLAHLQAGLS 184 Query 187 GSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVM 246 DP+NIQYTSGTT +PKG TLSH NILNNG+ VGEL YT D++CIPVPFYHCFGMVM Sbjct 185 ADDPINIQYTSGTTGFPKGATLSHHNILNNGFFVGELCNYTEHDKVCIPVPFYHCFGMVM 244 Query 247 GNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSL 306 GNLA TSHGA MVIPAP FDP ATL AV ERCTSLYGVPTMFIAEL PDF +++L SL Sbjct 245 GNLACTSHGACMVIPAPAFDPRATLEAVAAERCTSLYGVPTMFIAELNHPDFGEFDLTSL 304 Query 307 RTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVG 366 RTGIMAG+ CPVEVM++VI RM M VSICYGMTETSPVSTQTR+DDS++RRV TVGRVG Sbjct 305 RTGIMAGSPCPVEVMKQVIDRMGMAEVSICYGMTETSPVSTQTRSDDSIERRVSTVGRVG 364 Query 367 PHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEM 426 PHLE+KVVDP TG TVPRG GE CTRGYSVM GYW P KTAE IDA WMHTGDLA M Sbjct 365 PHLEVKVVDPETGLTVPRGEPGELCTRGYSVMLGYWEQPDKTAEAIDAARWMHTGDLAVM 424 Query 427 DPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVK 486 D GYV I GRIKD+V+RGGEN+ PREIEE L+THPDI+D VIGVPD KYGEELMA V+ Sbjct 425 DGDGYVNITGRIKDMVIRGGENLYPREIEEFLYTHPDILDAQVIGVPDEKYGEELMAWVR 484 Query 487 LRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRGQ 546 +R A LT E++RE+C G++A +KIPRY+ +VDEFPMTVTGKVRKVEMR++++ L + Sbjct 485 MRQGASPLTAEKVREFCSGKLAHYKIPRYVHVVDEFPMTVTGKVRKVEMREKSISLLGLE 544 Query 547 Q 547 Q Sbjct 545 Q 545 >gi|184201926|ref|YP_001856133.1| putative fatty-acid--CoA ligase [Kocuria rhizophila DC2201] gi|183582156|dbj|BAG30627.1| putative fatty-acid--CoA ligase [Kocuria rhizophila DC2201] Length=540 Score = 723 bits (1867), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/531 (66%), Positives = 413/531 (78%), Gaps = 1/531 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY GP+ LLE TIG NL TA R+ EALVD+ A +R+ Y E L DV LATGL R Sbjct 7 SYAAGPTDQPLLEQTIGENLHETAERFPDHEALVDVAAGKRWTYREFLHDVRSLATGLDR 66 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 G+ GDRVGIW PN WEWVL+QYA+AE+GAILV INP+YR EV++AL Q+G++ V++ Sbjct 67 LGVRTGDRVGIWGPNSWEWVLMQYASAELGAILVNINPSYRQHEVDFALAQAGISTVVSS 126 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQTAARLDGSDPVN 192 +FK++DYA ML P P+L +V+L+ S WDAL EPD L A L D VN Sbjct 127 PAFKNSDYAGMLEAARPHAPELQNVVLMGSPEWDALF-VEPDDARLASVATGLHADDAVN 185 Query 193 IQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLAAT 252 IQYTSGTT PKG TLSHRNILNNGY +GELL YTA+DRI + P YHCFGMV+GNLAAT Sbjct 186 IQYTSGTTGRPKGATLSHRNILNNGYFIGELLHYTAEDRIVVVPPLYHCFGMVIGNLAAT 245 Query 253 SHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGIMA 312 SHG A+++ PGFDP A LRAV ER TSLYGVPTMFIAEL LPDF DY+L +LRTG+MA Sbjct 246 SHGCAIILSGPGFDPRAALRAVAQERATSLYGVPTMFIAELELPDFGDYDLSTLRTGVMA 305 Query 313 GAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLEIK 372 G+ CP+EVMRKVIS MHM V+ICYGMTETSPVS QTR+DDS+DRRVGTVGRV PH+E+K Sbjct 306 GSPCPMEVMRKVISEMHMSEVAICYGMTETSPVSFQTRSDDSLDRRVGTVGRVHPHVEVK 365 Query 373 VVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYV 432 +VDP+TGETVPRG GEFCTRGYSVM GYW +KT E ID +GW+HTGD+A MD GY Sbjct 366 IVDPSTGETVPRGQAGEFCTRGYSVMKGYWGQEEKTREAIDPEGWLHTGDIAVMDEDGYA 425 Query 433 RIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAP 492 +I GRIKD+V+RGGENI PRE+EE L+THPD+VD VIGVP KYGEELM ++LR+ AP Sbjct 426 QITGRIKDMVIRGGENIYPREVEEFLYTHPDVVDAQVIGVPSEKYGEELMVWLRLRDGAP 485 Query 493 ELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 LT E + E+ G+I+R KIPRY+ +V+EFPMTVTGKVRKVEMR++AL+ L Sbjct 486 ALTAEAILEFADGKISRHKIPRYVHVVEEFPMTVTGKVRKVEMREEALKLL 536 >gi|284989388|ref|YP_003407942.1| AMP-dependent synthetase and ligase [Geodermatophilus obscurus DSM 43160] gi|284062633|gb|ADB73571.1| AMP-dependent synthetase and ligase [Geodermatophilus obscurus DSM 43160] Length=551 Score = 720 bits (1858), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/540 (65%), Positives = 411/540 (77%), Gaps = 2/540 (0%) Query 6 VVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHR 65 + P SY G S LL TIGANL TA R G EALV+ RRF+Y E + +V Sbjct 1 MTQPALPSYSSGTSTVPLLGDTIGANLDRTATRVGDHEALVECATGRRFSYPEFVAEVDA 60 Query 66 LATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSG 125 +A GL G+ GDRVGIWAPN EW VQYATA++GAILV INPAYR E+ Y L Q+G Sbjct 61 VALGLDALGVAKGDRVGIWAPNCAEWAFVQYATAKLGAILVNINPAYRTHELAYVLEQAG 120 Query 126 VAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL--AGAEPDLPALQQTAA 183 ++++++ F+ +DY AM+AEV CPDL +V+ L D W+ L G D L + A Sbjct 121 ISVLVSAPEFRTSDYRAMVAEVREDCPDLREVLFLGDDAWEQLLTTGRAGDRELLVRREA 180 Query 184 RLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFG 243 L DP+NIQYTSGTT +PKG TL+H N+LNNG+ VGE GYT DRICIPVP+YHCFG Sbjct 181 ELSADDPINIQYTSGTTGFPKGATLTHHNLLNNGFFVGEGCGYTEADRICIPVPYYHCFG 240 Query 244 MVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYEL 303 M MGNLAATSHGA MVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAEL LPDF Y+L Sbjct 241 MGMGNLAATSHGATMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELALPDFGTYDL 300 Query 304 GSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVG 363 SLRTGIMAG+ CPVEVM++V+S M M V+ICYGMTETSPVSTQT ADD +DRR TVG Sbjct 301 SSLRTGIMAGSPCPVEVMKRVVSEMGMTEVTICYGMTETSPVSTQTGADDDLDRRTSTVG 360 Query 364 RVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDL 423 RV PHLE+KV+DP TG TVPRG GEFCTRGYSVM GYW++P+KTAEVIDA WMHTGDL Sbjct 361 RVHPHLEVKVIDPETGLTVPRGTPGEFCTRGYSVMLGYWDEPEKTAEVIDAARWMHTGDL 420 Query 424 AEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMA 483 A MD GY+ I GRIKD+V+RGGEN+ PRE+EE L+THPD+VD VIGVPD ++GEELMA Sbjct 421 AVMDAEGYLNIVGRIKDMVIRGGENVYPREVEEFLYTHPDVVDAQVIGVPDERFGEELMA 480 Query 484 VVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 V+LR A LT E LR++C GR+A +KIPRY+ IVD FPMTVTGKVRKVEMR+ ++ L Sbjct 481 WVRLREGAEPLTPEALRQFCSGRLAHYKIPRYVKIVDGFPMTVTGKVRKVEMREVSVREL 540 >gi|111023051|ref|YP_706023.1| AMP-binding domain protein [Rhodococcus jostii RHA1] gi|110822581|gb|ABG97865.1| CoA ligase [Rhodococcus jostii RHA1] Length=545 Score = 717 bits (1851), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/536 (64%), Positives = 413/536 (78%), Gaps = 5/536 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G +L TIG N T A +G R+ALVD + RR+ Y+EL DV +A GL++ Sbjct 7 SYTNGVWDAPMLGDTIGDNFDRTVAAHGDRDALVDRPSGRRWTYAELRRDVDAVAAGLLK 66 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 GIG GDRVGIWAPN EW L+Q+ATA+IGA+LV INPAYR E++Y L Q+G+ ++++ Sbjct 67 RGIGKGDRVGIWAPNCPEWTLIQFATAKIGAVLVNINPAYRAHELKYVLDQAGIRLLVSA 126 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRW-----DALAGAEPDLPALQQTAARLDG 187 FK +DYAAM+ EV P+CPDL V+LL S W D +A E D L A L Sbjct 127 PEFKSSDYAAMIEEVRPQCPDLEMVVLLGSAEWSRLASDGMAAHEADPALLPAAQAALSS 186 Query 188 SDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMG 247 DP+NIQYTSGTT +PKG TLSH NILNNGY VGEL YT DR+CIPVPFYHCFGMVMG Sbjct 187 DDPINIQYTSGTTGFPKGATLSHHNILNNGYFVGELCHYTENDRVCIPVPFYHCFGMVMG 246 Query 248 NLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLR 307 NLA TSHGA M+IP P FDP ATL+AV+ E+CTSLYGVPTMFIAEL PDF ++L SLR Sbjct 247 NLACTSHGATMIIPGPSFDPTATLQAVEAEKCTSLYGVPTMFIAELAEPDFASFDLSSLR 306 Query 308 TGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGP 367 TGIMAG+ CPVEVM++VI +M M VSICYGMTETSPVS QTR+DD++D+RV TVGRVGP Sbjct 307 TGIMAGSPCPVEVMKQVIEQMGMAEVSICYGMTETSPVSLQTRSDDTIDQRVSTVGRVGP 366 Query 368 HLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMD 427 HLE+K+VDPATG TVPRG GE CTRGYSVM GYWN+P+KTAE IDA WMHTGD+ MD Sbjct 367 HLEVKIVDPATGLTVPRGTPGELCTRGYSVMLGYWNNPEKTAEAIDAGRWMHTGDIGVMD 426 Query 428 PSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKL 487 GYV I GRIKD+V+RGGEN+ PREIEE L+THPDI+D VIGVPDAKYGEELM V++ Sbjct 427 SDGYVAITGRIKDMVIRGGENVYPREIEEFLYTHPDILDAQVIGVPDAKYGEELMVWVRM 486 Query 488 RNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 ++ A L ++RE+C G++A +KIP+Y+ +VDEFPMTVTGKVRKVEMR+Q+L+ + Sbjct 487 KDGAEPLDAAKVREFCTGKLAHYKIPKYVHVVDEFPMTVTGKVRKVEMREQSLDLI 542 >gi|262201331|ref|YP_003272539.1| AMP-dependent synthetase and ligase [Gordonia bronchialis DSM 43247] gi|262084678|gb|ACY20646.1| AMP-dependent synthetase and ligase [Gordonia bronchialis DSM 43247] Length=542 Score = 716 bits (1847), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/541 (68%), Positives = 414/541 (77%), Gaps = 6/541 (1%) Query 10 NRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATG 69 L+Y RG P+LL TIGA LA T Y ALVD A R++ Y E +V LA G Sbjct 2 TELAYARGEENPALLTETIGATLAFTVEAYPDNVALVDAAAGRQWTYREFHREVRALAAG 61 Query 70 LVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMV 129 L+R G+G GDRVG+W+PNR+EWV QYATAEIGAILV INPAYR EVEYAL QS + +V Sbjct 62 LLRLGVGVGDRVGVWSPNRYEWVFTQYATAEIGAILVNINPAYRQNEVEYALAQSEIGVV 121 Query 130 IAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAG--AEPDLPALQQTAARLDG 187 IA FKD+ YA ML E P+CP+L +V+L S +WD L + +L + AA L Sbjct 122 IAAERFKDSAYAQMLDEARPKCPELREVVLFSSSQWDELTADPTDAELAQVADVAATLSP 181 Query 188 SDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMG 247 D +NIQYTSGTT +PKG TL+HRNI NNGYLVGELL YT DRICIPVPFYHCFGMVMG Sbjct 182 DDAINIQYTSGTTGFPKGATLTHRNIGNNGYLVGELLNYTDADRICIPVPFYHCFGMVMG 241 Query 248 NLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDF-TDYELGSL 306 NLAATSHGAAMVIPAP FDP ATLRAV + RCTSLYGVPTMFIAEL L D ++L SL Sbjct 242 NLAATSHGAAMVIPAPAFDPEATLRAVAEYRCTSLYGVPTMFIAELALLDGGASHDLSSL 301 Query 307 RTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVG 366 RTGIMAG+ CP VMR+VI RM+M VSICYGMTETSPVSTQTR DD ++ RV TVGRVG Sbjct 302 RTGIMAGSPCPEHVMRQVIDRMNMGQVSICYGMTETSPVSTQTRVDDPLELRVTTVGRVG 361 Query 367 PHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEM 426 PHLEIKVVDP TGET+PRG GEFCTRGYSVM GYWN P+KTAE ID DGWMHTGDLA M Sbjct 362 PHLEIKVVDPVTGETLPRGETGEFCTRGYSVMKGYWNQPEKTAEAIDGDGWMHTGDLAVM 421 Query 427 DPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVK 486 P GYV I GRIKD+V+RGGENI PREIEE L+THPDI+D VIGVPD KYGEELMA V+ Sbjct 422 APDGYVAITGRIKDMVIRGGENIYPREIEEFLYTHPDILDAQVIGVPDEKYGEELMAWVR 481 Query 487 LRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQA---LEYL 543 LR A +LT E +RE+ G+IA KIPRY+ +V EFPMTVTGKVRKV MR++A LE+L Sbjct 482 LRKPATDLTAEDVREFATGKIAHHKIPRYVHVVKEFPMTVTGKVRKVAMREEAAEILEHL 541 Query 544 R 544 R Sbjct 542 R 542 >gi|333922026|ref|YP_004495607.1| Substrate-CoA ligase [Amycolicicoccus subflavus DQS3-9A1] gi|333484247|gb|AEF42807.1| Substrate-CoA ligase [Amycolicicoccus subflavus DQS3-9A1] Length=556 Score = 713 bits (1840), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/539 (64%), Positives = 412/539 (77%), Gaps = 5/539 (0%) Query 12 LSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLV 71 +SY G S L+ TIG T A +G REALVD + RR+ Y+ L +V+ +A GL+ Sbjct 18 ISYTSGISDTPLIGDTIGDTFDRTVAAFGDREALVDRPSGRRWTYAALADEVNTVAAGLI 77 Query 72 RAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIA 131 G+ DRVGIWAPN EWV Q ATA+IGAILV INPAYR +E+EY L Q+G+ +++A Sbjct 78 ALGVRKEDRVGIWAPNCAEWVFTQLATAKIGAILVNINPAYRTQELEYVLNQAGIKVLVA 137 Query 132 VASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL--AGAEP---DLPALQQTAARLD 186 A+FK +DY AM+AEV P+ L I L S W ++ +GA+ D +++ A+L Sbjct 138 AAAFKTSDYQAMVAEVRPKTTRLEHAIFLGSSEWHSIFTSGADSLRADADIVRKAQAKLS 197 Query 187 GSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVM 246 D +NIQYTSGTT +PKG TLSH NILNNG+ VGELL YT +DR+CIPVPFYHCFGMVM Sbjct 198 ADDAINIQYTSGTTGFPKGATLSHHNILNNGFFVGELLSYTEEDRVCIPVPFYHCFGMVM 257 Query 247 GNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSL 306 GNLA SHG+ MVIPAP F+P ATL+AV +ERCTSLYGVPTMFIAEL PDF Y+ +L Sbjct 258 GNLACVSHGSTMVIPAPSFEPQATLQAVSEERCTSLYGVPTMFIAELNEPDFDGYDFSNL 317 Query 307 RTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVG 366 RTG+MAG+ CPVE+M++VI RM M VSICYGMTETSPVSTQTR +DS++ RV TVG+VG Sbjct 318 RTGVMAGSPCPVEIMKQVIERMGMAEVSICYGMTETSPVSTQTRKNDSIEHRVSTVGQVG 377 Query 367 PHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEM 426 PHLEIK+VDPATG+TVPRG GEFCTRGYSVM GYW+ P KTAE IDA WMHTGD+A M Sbjct 378 PHLEIKIVDPATGQTVPRGTPGEFCTRGYSVMLGYWDQPDKTAEAIDAARWMHTGDIAVM 437 Query 427 DPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVK 486 D GYV I GRIKD+V+RGGEN+ PREIEE L+THPD++D VIGVPD KYGEELMA V+ Sbjct 438 DDEGYVSITGRIKDMVIRGGENVYPREIEEFLYTHPDVLDAQVIGVPDEKYGEELMAWVQ 497 Query 487 LRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRG 545 LR DA LT E LRE+C G++A +KIPRY+ IVDEFPMT+TGK+RKVEMR+ A + + G Sbjct 498 LREDAEPLTAEALREFCTGKLAHYKIPRYVHIVDEFPMTITGKIRKVEMREIAKQLISG 556 >gi|311894125|dbj|BAJ26533.1| putative long-chain fatty-acid--CoA ligase [Kitasatospora setae KM-6054] Length=562 Score = 711 bits (1834), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/546 (66%), Positives = 409/546 (75%), Gaps = 8/546 (1%) Query 8 DPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLA 67 DP LS+ GPS LL+ T+GA L + REA+V+ RR+ Y+ L DV +A Sbjct 17 DPLPLSHASGPSGTPLLDDTVGAALDRAVRSFPEREAVVEHATGRRWTYARLAADVDAVA 76 Query 68 TGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVA 127 GL G+G GDRVGIWAPNR EW LVQYATA +GAILVTINPAYR E+EY L Q+GV Sbjct 77 LGLRARGVGKGDRVGIWAPNRAEWTLVQYATARLGAILVTINPAYRAHELEYVLNQAGVR 136 Query 128 MVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRW--------DALAGAEPDLPALQ 179 +++A FK +DYAAM+AEV PRCP+LADV+LL+ W A A + L Sbjct 137 LLVAAERFKTSDYAAMIAEVRPRCPELADVVLLDGPDWPALLAAGEAAGAAGDGGQAELA 196 Query 180 QTAARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFY 239 Q L DP+NIQYTSGTT +PKG TLSHRNILNNGY VGEL YT +DRICIPVPFY Sbjct 197 QIERGLSADDPINIQYTSGTTGFPKGATLSHRNILNNGYFVGELCNYTERDRICIPVPFY 256 Query 240 HCFGMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFT 299 HCFGMVMGNLAA SHGA VIPAP FD A TL AV ERCTSLYGVPTMFIAEL P F Sbjct 257 HCFGMVMGNLAAVSHGACTVIPAPAFDAATTLAAVAAERCTSLYGVPTMFIAELADPGFD 316 Query 300 DYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRV 359 Y+L SLRTGIMAGA CP EVM+ V+ RM M VSICYGMTETSPVSTQTRADDSV+RRV Sbjct 317 GYDLSSLRTGIMAGAPCPTEVMKGVMERMGMTEVSICYGMTETSPVSTQTRADDSVERRV 376 Query 360 GTVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMH 419 TVGRVGPHLE+KVVDP TG TVPRG GE CTRGYSVM GYW +P KTAE +D DGWMH Sbjct 377 STVGRVGPHLEVKVVDPETGHTVPRGEPGELCTRGYSVMLGYWAEPVKTAEAVDPDGWMH 436 Query 420 TGDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGE 479 TGDLA MD GY+ I GRIKD+V+RGGEN+ PRE+EE L+ HPD++D VIGVPDAKYGE Sbjct 437 TGDLAVMDADGYLSITGRIKDMVIRGGENVYPREVEEFLYAHPDVLDVQVIGVPDAKYGE 496 Query 480 ELMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQA 539 ELMA V++R A LT E +R +C GR+A FKIPRY+ +VDEFPMTVTGKVRKVEMR++A Sbjct 497 ELMAWVRMREGARPLTAEAVRAFCTGRLAHFKIPRYVHVVDEFPMTVTGKVRKVEMRERA 556 Query 540 LEYLRG 545 L G Sbjct 557 AAILAG 562 >gi|134097188|ref|YP_001102849.1| AMP-binding domain protein [Saccharopolyspora erythraea NRRL 2338] gi|291005355|ref|ZP_06563328.1| AMP-binding domain protein [Saccharopolyspora erythraea NRRL 2338] gi|133909811|emb|CAL99923.1| AMP-dependent synthetase and ligase [Saccharopolyspora erythraea NRRL 2338] Length=538 Score = 710 bits (1833), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/535 (67%), Positives = 414/535 (78%), Gaps = 2/535 (0%) Query 9 PNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLAT 68 P LSY G S LL TIG NL TAAR+ R+AL++ RR++Y E + DV LA Sbjct 2 PAELSYASGTSDVPLLGDTIGGNLDRTAARFPERDALIEHTTGRRWSYREFVADVDALAL 61 Query 69 GLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAM 128 GL+ AGI GDRVGIW+PNR EW LVQYATA IGAILV INP+YRV E+EY L Q+G+ M Sbjct 62 GLLGAGITKGDRVGIWSPNRAEWTLVQYATARIGAILVNINPSYRVHELEYVLDQAGIRM 121 Query 129 VIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQTAARLDGS 188 +++ +FK +DY +M+ +V +C L V+ L+ D WDAL + D PA + A L Sbjct 122 LVSARAFKTSDYVSMVEQVRAKCAALERVVFLDGDEWDALFDRDGD-PA-RLAAIELSAD 179 Query 189 DPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGN 248 DP+NIQYTSGTT +PKG TLSH NILNNG+ VGEL YT DR+CIPVPFYHCFGMVMGN Sbjct 180 DPINIQYTSGTTGFPKGATLSHHNILNNGFFVGELCRYTEADRVCIPVPFYHCFGMVMGN 239 Query 249 LAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRT 308 LA TS GAAMVIP+ GFDP L AV +ERCTSLYGVPTMFIAEL P+F D++L SLRT Sbjct 240 LACTSRGAAMVIPSEGFDPRTALAAVAEERCTSLYGVPTMFIAELDHPEFADFDLSSLRT 299 Query 309 GIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPH 368 GIMAG+ CPVEVM++VI RM M V+ICYGMTETSPVSTQTRADDS++RRV TVGRVGPH Sbjct 300 GIMAGSPCPVEVMKQVIDRMGMAEVAICYGMTETSPVSTQTRADDSLERRVSTVGRVGPH 359 Query 369 LEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDP 428 LE+K+VDPATG TVPRG GE CTRGYSVM GYW KTAEVIDA WMHTGDLA MD Sbjct 360 LEVKIVDPATGLTVPRGEPGELCTRGYSVMLGYWEQADKTAEVIDAARWMHTGDLAVMDA 419 Query 429 SGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLR 488 YV I GRIKD+V+RGGENI PREIEE L+THPDI+D V+GVPDA+YGEELMA V+LR Sbjct 420 DDYVGITGRIKDMVIRGGENIYPREIEEFLYTHPDILDAQVVGVPDARYGEELMAWVRLR 479 Query 489 NDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 A ELT+E LRE+C G++A +KIPRY+ +V+EFPMTVTGKVRKVEMR++A L Sbjct 480 EGAAELTVEALREFCTGKLAHYKIPRYVHVVEEFPMTVTGKVRKVEMREEAKRLL 534 >gi|254385476|ref|ZP_05000803.1| acyl-CoA synthetase [Streptomyces sp. Mg1] gi|194344348|gb|EDX25314.1| acyl-CoA synthetase [Streptomyces sp. Mg1] Length=546 Score = 710 bits (1832), Expect = 0.0, Method: Compositional matrix adjust. Identities = 355/533 (67%), Positives = 405/533 (76%), Gaps = 2/533 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G LL TIG NL T R+ R+ALVD A RR+ Y+E DV LA GL+ Sbjct 10 SYASGVFEVPLLGDTIGENLDRTVRRFPGRDALVDRAAGRRWTYAEFAADVDALALGLLD 69 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 I GDRVGIWAPNR EW LVQYATA IGAILVT+NPAYR E+EY LRQSG+ M++A Sbjct 70 LDITKGDRVGIWAPNRAEWTLVQYATARIGAILVTVNPAYRSHELEYVLRQSGMRMLVAA 129 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALA--GAEPDLPALQQTAARLDGSDP 190 FK +DYAAM+ EV P CP+L +LL+ RW L G + D L + A L DP Sbjct 130 ERFKSSDYAAMIEEVRPGCPELEFTVLLDGPRWTDLLERGRQGDPARLARAQAELSADDP 189 Query 191 VNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLA 250 +NIQYTSGTT +PKG TLSH NILNNG+ VGEL YT DR+CIPVPFYHCFGMVMGNLA Sbjct 190 INIQYTSGTTGFPKGATLSHHNILNNGFFVGELCHYTELDRVCIPVPFYHCFGMVMGNLA 249 Query 251 ATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGI 310 TSHGAAMVIPAP F+PAATL AV+ E CTSLYGVPTMFI+ L P F Y+L LRTGI Sbjct 250 CTSHGAAMVIPAPSFEPAATLAAVEAESCTSLYGVPTMFISALADPGFDSYDLSGLRTGI 309 Query 311 MAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLE 370 MAG+ CPVEVM++VI RM M VSICYGMTETSPVSTQTRADDSV+RRV TVGRVGPHLE Sbjct 310 MAGSPCPVEVMKEVIDRMGMTEVSICYGMTETSPVSTQTRADDSVERRVSTVGRVGPHLE 369 Query 371 IKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSG 430 +KVVDPATG TVPRG GE CTRGYSVM GYW +P++TAE +DA WMHTGDLA MD G Sbjct 370 VKVVDPATGRTVPRGEPGELCTRGYSVMLGYWGEPERTAEAVDAARWMHTGDLAVMDEDG 429 Query 431 YVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRND 490 Y+ I GRIKD+V+RGGEN+ PREIEE LHTHPD++D VIGVPD KYGEELMA V++R Sbjct 430 YLSITGRIKDMVIRGGENLYPREIEEFLHTHPDVLDVQVIGVPDPKYGEELMAWVRMREG 489 Query 491 APELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 A LT E +R YC GR+A FKIPRY+ +V+EFPMTVTGK+RK+EMR+ A L Sbjct 490 AEPLTAETVRAYCAGRLAHFKIPRYVHVVEEFPMTVTGKIRKIEMRETAARLL 542 >gi|331699394|ref|YP_004335633.1| Long-chain-fatty-acid--CoA ligase [Pseudonocardia dioxanivorans CB1190] gi|326954083|gb|AEA27780.1| Long-chain-fatty-acid--CoA ligase [Pseudonocardia dioxanivorans CB1190] Length=554 Score = 708 bits (1828), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/533 (65%), Positives = 406/533 (77%), Gaps = 2/533 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G S LL TIG NL TA EALV++ RR+ Y++L DV +A GL+R Sbjct 11 SYASGISEVPLLGDTIGDNLDRTATAQPDVEALVEVPTARRWTYAQLREDVDVVAMGLMR 70 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 AG+G GDRVGIWAPN EW LVQYATA+IGAILV INPAYR E+EY L Q+G+ M+++ Sbjct 71 AGLGKGDRVGIWAPNMAEWTLVQYATAKIGAILVNINPAYRTHELEYVLNQAGIRMLVSA 130 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL--AGAEPDLPALQQTAARLDGSDP 190 FK +DY M+ +V CP L V+++ W+AL +G D L + A L DP Sbjct 131 EKFKTSDYVGMIEKVRGSCPALEQVVIIGGPEWEALVESGRGGDREELARLQAALSPDDP 190 Query 191 VNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLA 250 +NIQYTSGTT +PKG TLSH NILNNGY VG L GYTA+DR+CIPVPFYHCFGMVMGNL Sbjct 191 INIQYTSGTTGFPKGATLSHHNILNNGYFVGRLCGYTAEDRVCIPVPFYHCFGMVMGNLG 250 Query 251 ATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGI 310 T++G+ MVIPA GFDP ATLRAV ERCTSLYGVPTMFIAEL PDF Y+L SLRTGI Sbjct 251 CTTNGSTMVIPAQGFDPEATLRAVAQERCTSLYGVPTMFIAELNHPDFASYDLSSLRTGI 310 Query 311 MAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLE 370 MAG+ CPVEVM++V+ RM M V+ICYGMTETSPVSTQTRADDSV+RRV TVGRV PH+E Sbjct 311 MAGSPCPVEVMKQVVDRMGMTEVTICYGMTETSPVSTQTRADDSVERRVSTVGRVHPHVE 370 Query 371 IKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSG 430 +KVVDP TG TVPRG GE CTRGYSVM GYW P KTAE IDA WMHTGDLA MD G Sbjct 371 VKVVDPETGLTVPRGQAGELCTRGYSVMLGYWEQPDKTAESIDAARWMHTGDLAVMDSDG 430 Query 431 YVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRND 490 Y+ I GRIKD+V+RGGEN+ PREIEE L+THPD++D VIGVPD KYGEEL A VKLR+ Sbjct 431 YLNITGRIKDMVIRGGENVYPREIEEFLYTHPDVLDAQVIGVPDIKYGEELCAWVKLRDG 490 Query 491 APELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 LT E++RE+ G++A +KIPRY+ +VDEFPMTVTGKVRKVEMR++++E L Sbjct 491 VEGLTAEQVREFATGKLAHYKIPRYVIVVDEFPMTVTGKVRKVEMREKSVELL 543 >gi|300783387|ref|YP_003763678.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32] gi|299792901|gb|ADJ43276.1| fatty-acyl-CoA synthase [Amycolatopsis mediterranei U32] gi|340524772|gb|AEK39977.1| AMP-binding domain protein [Amycolatopsis mediterranei S699] Length=548 Score = 708 bits (1828), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/534 (67%), Positives = 408/534 (77%), Gaps = 3/534 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY GPS LL TIG + T A REALV++ RR+ Y++L DV LA GL++ Sbjct 4 SYASGPSEVPLLGDTIGDDFDRTVAADPDREALVEVPTDRRWTYAQLRDDVDALALGLLK 63 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 G+ GDRVGIWAPN EW L+QYATA+IGAILV INP+YR E+EY L+Q+G++++++ Sbjct 64 TGVVKGDRVGIWAPNMAEWTLLQYATAKIGAILVNINPSYRTHELEYVLKQAGISVLVSA 123 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL--AGAEPDLPALQQTAARLDGSDP 190 +FK +DYA M+ EV CP+L V+L+ S WD L AG D L A L DP Sbjct 124 RAFKTSDYAGMIEEVRGNCPELRSVVLIGSGAWDELLAAGRCGDAARLAAAQAALSPDDP 183 Query 191 VNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLA 250 +NIQYTSGTT +PKG TLSH NILNNGY VG L GYT DR+CIPVPFYHCFGMVMGNLA Sbjct 184 INIQYTSGTTGFPKGATLSHHNILNNGYFVGALCGYTPADRVCIPVPFYHCFGMVMGNLA 243 Query 251 ATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTM-FIAELGLPDFTDYELGSLRTG 309 TSHGA MVIPA GFDP ATL AVQ ERCTSLYGVPTM FIAEL P F Y+L SLRTG Sbjct 244 CTSHGATMVIPAQGFDPEATLEAVQRERCTSLYGVPTMLFIAELNHPKFAAYDLSSLRTG 303 Query 310 IMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHL 369 IMAG+ CPVEVM++V+SRM M V+ICYGMTETSPVSTQTR DDS+D RV TVGRV PHL Sbjct 304 IMAGSPCPVEVMKQVVSRMGMEQVTICYGMTETSPVSTQTRMDDSLDLRVSTVGRVHPHL 363 Query 370 EIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPS 429 EIK+VDPATG TVPRG GE CTRGYSVM GYWNDP KTAE IDA WMHTGDLA MD Sbjct 364 EIKLVDPATGLTVPRGEAGELCTRGYSVMLGYWNDPGKTAEAIDAARWMHTGDLAVMDAD 423 Query 430 GYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN 489 GYV I GRIKD+V+RGGENI PREIEE L+THPDIVD VIGVPD KYGEEL A VKLR+ Sbjct 424 GYVNITGRIKDMVIRGGENIYPREIEEFLYTHPDIVDAQVIGVPDVKYGEELCAWVKLRD 483 Query 490 DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 A E+T E LR + G++A +KIPRY+ +VDEFPMTVTGKVRK+EMR++++ L Sbjct 484 HAAEVTAETLRAFATGKLAHYKIPRYVLVVDEFPMTVTGKVRKIEMREKSVRIL 537 >gi|296270056|ref|YP_003652688.1| AMP-dependent synthetase and ligase [Thermobispora bispora DSM 43833] gi|296092843|gb|ADG88795.1| AMP-dependent synthetase and ligase [Thermobispora bispora DSM 43833] Length=544 Score = 706 bits (1822), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/534 (65%), Positives = 407/534 (77%), Gaps = 7/534 (1%) Query 12 LSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLV 71 LSY G S LL TIG N T AR+G REALV+ RR+ Y+EL V+ +A GL+ Sbjct 5 LSYSSGVSDVPLLGETIGENFERTVARFGAREALVEAATGRRWTYAELDAAVNEVALGLL 64 Query 72 RAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIA 131 GI GDRVGIW+PN EWV VQYATA+IGAILV +NPAYR E+EY +RQSG+ ++I+ Sbjct 65 ARGIKKGDRVGIWSPNCAEWVFVQYATAKIGAILVNVNPAYRAHELEYVVRQSGMRLLIS 124 Query 132 VASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALA--GAEPDLPALQQTAARLDGSD 189 +++ +DY AM+ ++G R DV+ + W+ L G D AL++ AA L D Sbjct 125 AVAYRTSDYRAMIEQIGFR-----DVVYIGEPSWERLIEDGRSLDAAALRERAATLTFDD 179 Query 190 PVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNL 249 P+NIQYTSGTT +PKG TLSH NILNNG+ VGELLGYT QDRIC+PVP YHCFGMVMGNL Sbjct 180 PINIQYTSGTTGFPKGATLSHHNILNNGFFVGELLGYTEQDRICLPVPLYHCFGMVMGNL 239 Query 250 AATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTG 309 AA SHG+ +V+PAPGFDP ATLRAV+ ERCTSLYGVPTMFIAELG P+F ++L SLRTG Sbjct 240 AAASHGSCVVLPAPGFDPEATLRAVERERCTSLYGVPTMFIAELGHPEFASFDLSSLRTG 299 Query 310 IMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHL 369 IMAG+ CPVEVM++V++ MHM V+ICYGMTETSPVST TR D + RR TVGRV PH+ Sbjct 300 IMAGSPCPVEVMKRVVADMHMSEVAICYGMTETSPVSTMTRRTDGLARRTETVGRVMPHI 359 Query 370 EIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPS 429 E+K+VDP TG TVPRG VGE CTRGYSVM GYW P+ TAE ID WMHTGDLA MD Sbjct 360 EVKIVDPETGRTVPRGQVGELCTRGYSVMLGYWEQPEATAEAIDRARWMHTGDLATMDEE 419 Query 430 GYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN 489 GYV I GRIKD+V+RGGENI PREIEE L+THPDI D VIGVPD KYGEELMA + +R Sbjct 420 GYVNIVGRIKDMVIRGGENIYPREIEEFLYTHPDIADVQVIGVPDEKYGEELMAWIIMRP 479 Query 490 DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 A LT ERLRE+C GR+A +KIPRY+ +VD FPMTVTGK+RKVEMR+QA+E L Sbjct 480 GAEPLTAERLREFCAGRLAHYKIPRYVHVVDSFPMTVTGKIRKVEMREQAIEIL 533 >gi|296140997|ref|YP_003648240.1| AMP-dependent synthetase and ligase [Tsukamurella paurometabola DSM 20162] gi|296029131|gb|ADG79901.1| AMP-dependent synthetase and ligase [Tsukamurella paurometabola DSM 20162] Length=541 Score = 706 bits (1821), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/533 (65%), Positives = 400/533 (76%), Gaps = 2/533 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SYD G + P+LL TIGA L T RYG R ALVD+ + RR+ Y ELL A GLVR Sbjct 5 SYDCGDADPALLTLTIGAQLELTTDRYGDRTALVDVPSGRRWTYDELLAAARSFAAGLVR 64 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 GI GDRVG+WAPN EWV+VQ+ TA G ILV +NP+YR RE+EYAL QSG+ V + Sbjct 65 KGIRRGDRVGVWAPNTPEWVIVQFGTALAGVILVNLNPSYRQRELEYALNQSGIVAVFTM 124 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPD--LPALQQTAARLDGSDP 190 +FK ++YAAML P PDL DV+ + W A D L L +L D Sbjct 125 TAFKTSEYAAMLEAARPEAPDLRDVVTFDGAAWAEYLAAPSDDELADLTDLGDQLSADDA 184 Query 191 VNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLA 250 +NIQYTSGTT +PKG TL+HRNILNNGYLVGELL YT QD ICIPVPFYHCFGMVMGNLA Sbjct 185 INIQYTSGTTGFPKGATLTHRNILNNGYLVGELLNYTEQDSICIPVPFYHCFGMVMGNLA 244 Query 251 ATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGI 310 A +HGAAMVIP P F P L AV E+CTSLYGVPTMFIAEL L +F Y+L SLRTGI Sbjct 245 AVTHGAAMVIPGPAFVPQDALAAVAAEKCTSLYGVPTMFIAELALAEFDSYDLSSLRTGI 304 Query 311 MAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLE 370 MAG+ CP EVMRKV+ RM M VSICYGMTETSPVSTQTR DD+++ RVGTVGRVGPHLE Sbjct 305 MAGSPCPEEVMRKVVDRMGMTEVSICYGMTETSPVSTQTRIDDALELRVGTVGRVGPHLE 364 Query 371 IKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSG 430 I+V+DP G +PRG VGE CTRGYSVM GYWN+ +KTAE IDA+GWMHTGDLA MD +G Sbjct 365 IRVIDPIDGTVMPRGEVGELCTRGYSVMKGYWNNEEKTAEAIDAEGWMHTGDLATMDDAG 424 Query 431 YVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRND 490 YVR+ GRIKD+V+RGGENI PREIEE L+THPDI+D VIGVPD KYGEELMA ++LR Sbjct 425 YVRVTGRIKDMVIRGGENIYPREIEEFLYTHPDILDAQVIGVPDEKYGEELMAWIQLREG 484 Query 491 APELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 T+E L+ + G+IAR KIPRY+ +V EFPMTV+GK+RKV+MR++++E L Sbjct 485 VDSFTVEDLKAFAEGKIARHKIPRYVHVVTEFPMTVSGKIRKVQMREESVELL 537 >gi|226305307|ref|YP_002765265.1| fatty-acid--CoA ligase [Rhodococcus erythropolis PR4] gi|229490610|ref|ZP_04384448.1| acyl-CoA synthetase family member 2 [Rhodococcus erythropolis SK121] gi|226184422|dbj|BAH32526.1| putative fatty-acid--CoA ligase [Rhodococcus erythropolis PR4] gi|229322430|gb|EEN88213.1| acyl-CoA synthetase family member 2 [Rhodococcus erythropolis SK121] Length=545 Score = 703 bits (1815), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/536 (65%), Positives = 407/536 (76%), Gaps = 5/536 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G +L TIG NL T A +G R+AL+D + RR+ Y E V+ LA GL+ Sbjct 7 SYTSGVWDGPMLGDTIGDNLDRTVAAHGDRDALIDHASGRRWTYREFAEQVNGLAAGLLS 66 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 G+G GDRVGIWAPN EW QYATA+IGAILV INPAYR E++Y L Q+G++ +++ Sbjct 67 RGVGKGDRVGIWAPNCPEWTFTQYATAKIGAILVNINPAYRSHELQYVLEQAGISTLVSA 126 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDA-----LAGAEPDLPALQQTAARLDG 187 ASFK +DYA+M+ V P+CPDL V+LL S WDA LA D L A L Sbjct 127 ASFKTSDYASMIETVRPQCPDLTSVLLLGSPEWDAVLADGLAAQASDPAPLAAAQAALSA 186 Query 188 SDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMG 247 D +NIQYTSGTT +PKG TLSH NILNNGY VGEL Y+ DR+CIPVPFYHCFGMVMG Sbjct 187 DDAINIQYTSGTTGFPKGATLSHHNILNNGYFVGELCHYSEVDRVCIPVPFYHCFGMVMG 246 Query 248 NLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLR 307 NLA TSHGAAMVIP P FDP A+L AVQ E+CTSLYGVPTMFIAEL LPDF ++L SLR Sbjct 247 NLACTSHGAAMVIPGPAFDPRASLEAVQAEKCTSLYGVPTMFIAELALPDFDSFDLSSLR 306 Query 308 TGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGP 367 TGIMAG+ CPVEVM++VI RM M VSICYGMTETSPVS QTR+DDS+++R TVGRVGP Sbjct 307 TGIMAGSPCPVEVMKQVIDRMGMSEVSICYGMTETSPVSLQTRSDDSIEQRTETVGRVGP 366 Query 368 HLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMD 427 HLEIK+VDPATG TVPRG GE CTRGYSVM GYW +P+KTAE IDA WMHTGD+ MD Sbjct 367 HLEIKIVDPATGLTVPRGEPGELCTRGYSVMLGYWENPEKTAEAIDAARWMHTGDIGVMD 426 Query 428 PSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKL 487 +GYV I GRIKD+V+RGGEN+ PREIEE L+THPDI+D VIGVPDAKYGEELM V++ Sbjct 427 EAGYVAITGRIKDMVIRGGENVYPREIEEFLYTHPDILDAQVIGVPDAKYGEELMVWVQM 486 Query 488 RNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 R A +L + +R +C G++A +KIPRY+ +VDEFPMTVTGKVRK+ MR+QA+E + Sbjct 487 REGADDLDADSVRAFCTGKLAHYKIPRYVHVVDEFPMTVTGKVRKIAMREQAIELI 542 >gi|302541757|ref|ZP_07294099.1| substrate-CoA ligase [Streptomyces hygroscopicus ATCC 53653] gi|302459375|gb|EFL22468.1| substrate-CoA ligase [Streptomyces himastatinicus ATCC 53653] Length=566 Score = 702 bits (1811), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/539 (64%), Positives = 405/539 (76%), Gaps = 2/539 (0%) Query 9 PNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLAT 68 P LSY G + LL TIGANLA R+G REALVD+ + RR+ Y+E V +A Sbjct 12 PAALSYASGTADLPLLGDTIGANLARAIERHGDREALVDIPSGRRWTYAEFGRSVDAVAL 71 Query 69 GLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAM 128 GL+ G+G GDRVGIWA N EWVLVQYATA IGAI+V +NPAYRV E+ Y LRQ+GV++ Sbjct 72 GLMAKGVGKGDRVGIWAVNCPEWVLVQYATARIGAIMVNVNPAYRVHELRYVLRQAGVSV 131 Query 129 VIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLP--ALQQTAARLD 186 +++ KD+DY M+ +V CP L DV+ + WD L A +P L + ARL Sbjct 132 LVSSTEHKDSDYRRMVEQVRAECPALRDVVYIGDRTWDGLVRAGEAVPEEKLAEREARLS 191 Query 187 GSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVM 246 DPVNIQYTSGTT +PKG TLSH NILNNGY VGE +GYT QDRIC+PVPFYHCFGMVM Sbjct 192 CDDPVNIQYTSGTTGFPKGATLSHHNILNNGYFVGETVGYTEQDRICLPVPFYHCFGMVM 251 Query 247 GNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSL 306 GNL AT+HGA +VIPAP FDPAATL AV+ ERCTSLYGVPTMFIAEL LPDF ++L SL Sbjct 252 GNLGATTHGACIVIPAPAFDPAATLSAVEQERCTSLYGVPTMFIAELALPDFATFDLTSL 311 Query 307 RTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVG 366 RTGIMAG+ CPVEVMR+V++ MHM VSICYGMTETSPVSTQTR DD + RR GTVGRV Sbjct 312 RTGIMAGSPCPVEVMRRVVAEMHMAEVSICYGMTETSPVSTQTRRDDDLARRTGTVGRVL 371 Query 367 PHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEM 426 P++E+KV+DPATG TVPRG GE CTRGYSVM GYW +P TAE ID GWMHTGDLA M Sbjct 372 PYVEVKVMDPATGLTVPRGTRGELCTRGYSVMLGYWEEPDLTAEAIDPAGWMHTGDLAVM 431 Query 427 DPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVK 486 D GYV+I GRIKD+++RGGEN+ PREIEE LHTHP I D V+GVPD KYGEE++A V Sbjct 432 DEHGYVQIVGRIKDMIIRGGENVYPREIEEFLHTHPKIADVQVVGVPDEKYGEEILACVI 491 Query 487 LRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRG 545 LR A LT + L +C GR+A FK+PR+L ++D FPMTV+GKVRKVE+R+ L G Sbjct 492 LREGATALTRDELARFCRGRLAAFKVPRHLRVMDAFPMTVSGKVRKVELRETGARELAG 550 >gi|324997477|ref|ZP_08118589.1| AMP-binding domain protein [Pseudonocardia sp. P1] Length=571 Score = 702 bits (1811), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/533 (64%), Positives = 407/533 (77%), Gaps = 2/533 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G S LL TIG N TAA +G +ALV++ RR+ Y++L DV RLA GL+ Sbjct 28 SYASGISDTPLLGDTIGDNFDRTAAAFGDNDALVEVATGRRWTYTQLREDVDRLAYGLLA 87 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 AG+ GDR+GIWAPN EW L QYATA++G +LV INP+YR E+E+ L+Q+G++ ++A Sbjct 88 AGVATGDRLGIWAPNMAEWTLTQYATAKLGVVLVNINPSYRTHELEFVLKQAGISTLVAA 147 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEP--DLPALQQTAARLDGSDP 190 FK ++Y M+AEV CPDL V++ SD W ALA D L + A L DP Sbjct 148 REFKTSNYEKMIAEVRGNCPDLLRVVIAGSDEWAALAAGGAAADRVRLAEIQASLAADDP 207 Query 191 VNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLA 250 +NIQYTSGTT +PKG TLSH NILNNGY VG+L GYT DR+CIPVPFYHCFGMVMGNL Sbjct 208 INIQYTSGTTGFPKGATLSHHNILNNGYYVGKLCGYTEADRVCIPVPFYHCFGMVMGNLG 267 Query 251 ATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGI 310 T++GA MVIPA GFDP ATL+AV+ ERCTSLYGVPTMFIAEL PDF Y+L SLRTGI Sbjct 268 CTTNGATMVIPAQGFDPKATLKAVEQERCTSLYGVPTMFIAELNDPDFASYDLSSLRTGI 327 Query 311 MAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLE 370 MAG+ CPVEVM++V+ RM M V+ICYGMTETSPVSTQTRADDS+D RV TVGRV PHLE Sbjct 328 MAGSPCPVEVMKQVVERMGMTEVTICYGMTETSPVSTQTRADDSLDLRVSTVGRVHPHLE 387 Query 371 IKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSG 430 +KVVDP TG+T+PRG GE CTRGYSVM GYW+ P+KTAEVID WMHTGD+A MD G Sbjct 388 VKVVDPETGKTLPRGEAGELCTRGYSVMLGYWDQPEKTAEVIDRARWMHTGDIAVMDDEG 447 Query 431 YVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRND 490 YV I GRIKD+V+RGGEN+ PREIEE L+THPD++D VIGVPDA+YGEEL A V LR Sbjct 448 YVNITGRIKDMVIRGGENVYPREIEEFLYTHPDVLDAQVIGVPDARYGEELCAWVVLREG 507 Query 491 APELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 A +T E L+E+ GR+A +KIPRY+ +VDEFPMTVTGKVRKVEMR++++ L Sbjct 508 AAAMTPESLKEFATGRLAHYKIPRYVLVVDEFPMTVTGKVRKVEMREKSVGLL 560 >gi|326383718|ref|ZP_08205403.1| AMP-dependent synthetase and ligase [Gordonia neofelifaecis NRRL B-59395] gi|326197482|gb|EGD54671.1| AMP-dependent synthetase and ligase [Gordonia neofelifaecis NRRL B-59395] Length=558 Score = 699 bits (1803), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/546 (64%), Positives = 411/546 (76%), Gaps = 15/546 (2%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G + P LL TIGA LAATAA+Y +AL+D R + Y+E DV LA GL+R Sbjct 9 SYAIGETDPPLLTQTIGATLAATAAKYPDSDALIDAAVDRTWTYAEFRRDVVALAAGLLR 68 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 G+ PGDRVG+WAPNR+EWVL Q+A AEIGAILV INP+YR E+ YAL+QSG ++V+A Sbjct 69 HGVAPGDRVGLWAPNRFEWVLTQFAAAEIGAILVVINPSYRRHELAYALKQSGTSLVLAA 128 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL--AGAEPDLPALQQTAARLDGSDP 190 F+D++YA ML +V + PDL +V+L ES + + A ++ ++ + + AA L DP Sbjct 129 ERFRDSEYAQMLDDVRDQTPDLREVVLFESATFTQMLEAPSDEEMAQVAEIAAGLRADDP 188 Query 191 VNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLA 250 +NIQYTSGTT PKGVTL+H NI NNGYLVG LL YT DRIC+PVPFYHCFGMVMGNLA Sbjct 189 INIQYTSGTTGSPKGVTLTHLNIGNNGYLVGALLEYTEADRICLPVPFYHCFGMVMGNLA 248 Query 251 ATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDF------------ 298 A + G+AMVIP P FDP L AV+ RCTSLYGVPTMFIAEL L D Sbjct 249 AIAFGSAMVIPGPAFDPKTALAAVEKYRCTSLYGVPTMFIAELALLDSGAGSEASGPSAH 308 Query 299 -TDYELGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDR 357 ++L SLRTGIMAG+ CP +VMR+VI M+M VSICYGMTETSPVSTQTR DD +D Sbjct 309 GETFDLSSLRTGIMAGSPCPEQVMRRVIGEMNMSQVSICYGMTETSPVSTQTRMDDDLDL 368 Query 358 RVGTVGRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGW 417 RV TVGRVGPHLEIK+ DP TGET+PRG GEF TRGYSVM GYWNDP+KTA+ +DADGW Sbjct 369 RVATVGRVGPHLEIKIADPITGETLPRGETGEFRTRGYSVMKGYWNDPEKTADALDADGW 428 Query 418 MHTGDLAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKY 477 M TGDLA M GYVRI GRIKD+V+RGGENI PREIEE L+THPDIVD VIGVPD KY Sbjct 429 MATGDLAVMGDDGYVRITGRIKDMVIRGGENIYPREIEEFLYTHPDIVDAQVIGVPDEKY 488 Query 478 GEELMAVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQ 537 GEELMA +++R A +T E +RE+ G I+R KIPRY+ +VDEFPMTVTGKVRKVEMR+ Sbjct 489 GEELMAWIRVREGAQPMTAETIREFAAGNISRHKIPRYVHVVDEFPMTVTGKVRKVEMRE 548 Query 538 QALEYL 543 +++E+L Sbjct 549 RSIEFL 554 >gi|226365555|ref|YP_002783338.1| AMP-binding domain protein [Rhodococcus opacus B4] gi|226244045|dbj|BAH54393.1| putative fatty-acid--CoA ligase [Rhodococcus opacus B4] Length=545 Score = 698 bits (1802), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/539 (64%), Positives = 404/539 (75%), Gaps = 6/539 (1%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G +L TIG N T A + R+ALVD + RR+ Y+EL DV +A GL++ Sbjct 7 SYTHGVWDAPMLGDTIGDNFDRTVAAHADRDALVDRPSGRRWTYAELKRDVDAVAAGLLK 66 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 GI GDRVGIWAPN EW L+QYATA+IGAILV INPAYR E++Y L Q+G+ ++++ Sbjct 67 RGIVKGDRVGIWAPNCPEWTLIQYATAKIGAILVNINPAYRAHELKYVLDQAGIRLLVSA 126 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRW-----DALAGAEPDLPALQQTAARLDG 187 FK +DYAAM+ EV P C D+ V+LL S W D +A D L A L Sbjct 127 PQFKSSDYAAMIEEVRPECGDVEMVVLLGSAEWSRLASDGMAAHAADPARLPAAQAALSP 186 Query 188 SDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMG 247 DP+NIQYTSGTT +PKG TLSH NILNNGY VGEL YT DR+CIPVPFYHCFGMVMG Sbjct 187 DDPINIQYTSGTTGFPKGATLSHHNILNNGYFVGELCHYTENDRVCIPVPFYHCFGMVMG 246 Query 248 NLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLR 307 NLA TSHGA MVIP FDP ATL+AV+ E+CTSLYGVPTMFIAEL DF Y+L SLR Sbjct 247 NLACTSHGATMVIPGRSFDPKATLQAVEAEKCTSLYGVPTMFIAELADHDFDSYDLSSLR 306 Query 308 TGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGP 367 TGIMAG+ CPVEVM+ VI M M VSICYGMTETSPVS QTR++D++D+RV TVGRVGP Sbjct 307 TGIMAGSPCPVEVMKHVIELMGMAEVSICYGMTETSPVSLQTRSNDTIDQRVSTVGRVGP 366 Query 368 HLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMD 427 HLEIK+VDPATG TVPRG GE CTRGYSVM GYWN+P+KTAE IDA WMHTGD+ MD Sbjct 367 HLEIKIVDPATGLTVPRGEPGELCTRGYSVMLGYWNNPEKTAEAIDAGRWMHTGDIGVMD 426 Query 428 PSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKL 487 GYV I GRIKD+V+RGGEN+ PREIEE L+THPDI+D VIGVPDAKYGEELM V++ Sbjct 427 CDGYVAITGRIKDMVIRGGENVYPREIEEFLYTHPDILDAQVIGVPDAKYGEELMVWVRM 486 Query 488 RNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLRGQ 546 + D L ++RE+C G++A +KIP+Y+ +VDEFPMTVTGKVRKVEMR+Q+L L GQ Sbjct 487 KEDTEPLDAAKVREFCTGKLAHYKIPKYVHVVDEFPMTVTGKVRKVEMREQSLS-LIGQ 544 >gi|118467988|ref|YP_889882.1| AMP-binding domain protein [Mycobacterium smegmatis str. MC2 155] gi|118169275|gb|ABK70171.1| acyl-CoA synthase [Mycobacterium smegmatis str. MC2 155] Length=537 Score = 693 bits (1788), Expect = 0.0, Method: Compositional matrix adjust. Identities = 323/531 (61%), Positives = 399/531 (76%), Gaps = 0/531 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SYD GP+ +LE TIGAN AA Y EALV++ RR+ Y+EL ++ A GL+ Sbjct 3 SYDAGPTGAPVLEETIGANFERIAATYPEHEALVEVATGRRWTYAELNDEIDATARGLMA 62 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 G+ GDRVGIWAPN EW++ Q+A A++GAILV INPAYR EV Y LRQSGV +++ Sbjct 63 LGVDKGDRVGIWAPNCAEWIMTQFAAAKVGAILVNINPAYRTHEVAYVLRQSGVRTLVSA 122 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQTAARLDGSDPVN 192 +SFK +DYA+M+AEV P CPDL DV+ L++D WD L + D A + A L +DP+N Sbjct 123 SSFKTSDYASMIAEVRPECPDLLDVVFLDNDDWDRLRANQVDDAAFHERMATLANTDPIN 182 Query 193 IQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLAAT 252 IQYTSGTT +PKG TLSHRNILNNG+ V EL+ DR+CI PFYHCFGMVMG L A Sbjct 183 IQYTSGTTGFPKGATLSHRNILNNGFFVTELIALGPDDRLCIVPPFYHCFGMVMGTLGAV 242 Query 253 SHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGIMA 312 SHG +VIPAPGFDP TL AV+ E+CT LYGVPTMFIA LG PDF +++L SLRTGIMA Sbjct 243 SHGTTIVIPAPGFDPGITLSAVESEKCTGLYGVPTMFIAMLGHPDFANFDLSSLRTGIMA 302 Query 313 GAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLEIK 372 G+ CP+EVM++V++ MHM V+ICYGMTETSPVS QT DD +DRR T+GR PH+EIK Sbjct 303 GSVCPIEVMKRVVADMHMAEVAICYGMTETSPVSCQTLIDDDLDRRTATIGRAHPHVEIK 362 Query 373 VVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYV 432 ++DP TGETV RG GEFCTRGYSVM GYWND +KT E +DADGWMHTGDLA M GY Sbjct 363 IIDPDTGETVERGQPGEFCTRGYSVMLGYWNDDEKTREAVDADGWMHTGDLAVMREDGYC 422 Query 433 RIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAP 492 I GRIKD+V+RGGENI PREIEE L+THPDI D VIGVPD +YGEE+ A ++++ P Sbjct 423 TIVGRIKDMVIRGGENIYPREIEEFLYTHPDIDDAQVIGVPDERYGEEICAWIRMKPGRP 482 Query 493 ELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 L +++RE+ G++A +KIPRY+ +VDEFPMTVTGK+RKV+MR++ + L Sbjct 483 PLDADKVREFASGKLAHYKIPRYVHVVDEFPMTVTGKIRKVQMREETVALL 533 >gi|317123519|ref|YP_004097631.1| AMP-dependent synthetase and ligase [Intrasporangium calvum DSM 43043] gi|315587607|gb|ADU46904.1| AMP-dependent synthetase and ligase [Intrasporangium calvum DSM 43043] Length=543 Score = 689 bits (1777), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/535 (64%), Positives = 405/535 (76%), Gaps = 5/535 (0%) Query 5 EVVDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVH 64 +V+DP LS+ RG + LLE TIG NL ATAAR+ REALVD+ RR+ Y+ LL DV Sbjct 3 DVLDPT-LSHTRGETDIPLLEQTIGDNLDATAARFPDREALVDVSQGRRWTYAALLADVD 61 Query 65 RLATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQS 124 RLA L+ G+ GDRVGIWAPN EW LVQYATA++GAILV INPAYR E+ Y L Q+ Sbjct 62 RLARALLAIGVKTGDRVGIWAPNCSEWTLVQYATAKMGAILVNINPAYRAHELHYVLGQA 121 Query 125 GVAMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPA--LQQTA 182 G++ ++A SFK ++Y M+ EV L VI + +D WD+ + A L Sbjct 122 GISTLVAAESFKSSNYREMIDEVRHDVASLERVIYIGTDDWDSTLAEADRVSATELSGIQ 181 Query 183 ARLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCF 242 A L SDP+NIQYTSGTT +PKG TLSHRNILNNG+ VGEL YT DR+CIPVPFYHCF Sbjct 182 AALKPSDPINIQYTSGTTGFPKGATLSHRNILNNGFFVGELCRYTEADRVCIPVPFYHCF 241 Query 243 GMVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYE 302 GMVMGNLA T+HGA MVIPAPGFDP ATL+AVQDE+CTSLYGVPTMFIAE LP F DY+ Sbjct 242 GMVMGNLACTTHGACMVIPAPGFDPTATLKAVQDEQCTSLYGVPTMFIAEWSLPSFADYD 301 Query 303 LGSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTV 362 + S+RTGIMAG+ CP +M+++I+ + ++ICYGMTETSPVSTQ R DD+ +++ GTV Sbjct 302 ISSVRTGIMAGSPCPAPLMKQLIAS-GIEEMTICYGMTETSPVSTQNRTDDTFEQKTGTV 360 Query 363 GRVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGD 422 GRV PHLEIK+VDP TGETV RG GEF T+GYSVM GYW P KTAE I+ DGWMHTGD Sbjct 361 GRVHPHLEIKIVDPGTGETVRRGQAGEFLTKGYSVMLGYWEQPDKTAEAIE-DGWMHTGD 419 Query 423 LAEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELM 482 L M GYV I GRIKD+V+RGGEN+ PREIEE L+THPDI+D VIGVPD+KYGEEL Sbjct 420 LGVMHDDGYVEITGRIKDMVIRGGENVYPREIEEFLYTHPDILDAQVIGVPDSKYGEELC 479 Query 483 AVVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQ 537 A V++R A LT E LRE+C G++A +KIPRY+ +VDEFPMTVTGK+RKVEMR+ Sbjct 480 AWVRMREGAEPLTAEALREFCTGQLAHYKIPRYVEVVDEFPMTVTGKIRKVEMRE 534 >gi|297191141|ref|ZP_06908539.1| acyl-CoA synthetase [Streptomyces pristinaespiralis ATCC 25486] gi|197723338|gb|EDY67246.1| acyl-CoA synthetase [Streptomyces pristinaespiralis ATCC 25486] Length=535 Score = 689 bits (1777), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/529 (64%), Positives = 404/529 (77%), Gaps = 2/529 (0%) Query 12 LSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLV 71 LSY G S LL TIG NLA TAA + REALVD+ A R+ Y+EL V LA GL+ Sbjct 3 LSYAHGVSGTPLLGETIGGNLARTAAAHPGREALVDVAAGARWTYAELDAAVDLLARGLL 62 Query 72 RAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIA 131 +G+G GDRVGIWA N EWVLVQYATA IGAI+V INPAYR E+EY L Q+GV++++A Sbjct 63 GSGVGKGDRVGIWAVNCAEWVLVQYATARIGAIMVNINPAYRAHELEYVLNQAGVSLLVA 122 Query 132 VASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLP--ALQQTAARLDGSD 189 + K +DY AM+ V P+CP L V + WD L A + L+ T A+L D Sbjct 123 SQTHKTSDYRAMVDAVRPKCPQLRAVHYIADSSWDVLLEAATGVTDEQLRDTQAQLSCDD 182 Query 190 PVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNL 249 PVNIQYTSGTT +PKG TLSH NILNNGY VGE++ YT QDR+CIPVPFYHCFGMVMGNL Sbjct 183 PVNIQYTSGTTGFPKGATLSHHNILNNGYFVGEMIAYTEQDRVCIPVPFYHCFGMVMGNL 242 Query 250 AATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTG 309 AATSHGA MVIPAP FDPAATLRAVQ ERCTSLYGVPTMFIAEL LP F Y+L +LRTG Sbjct 243 AATSHGACMVIPAPSFDPAATLRAVQQERCTSLYGVPTMFIAELNLPGFASYDLSTLRTG 302 Query 310 IMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHL 369 IMAG+ CPVEVM++V++ M+M VSICYGMTETSPVSTQTR DD ++RR GTVGRV PH+ Sbjct 303 IMAGSPCPVEVMKRVVAEMNMAEVSICYGMTETSPVSTQTRRDDDLERRTGTVGRVMPHI 362 Query 370 EIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPS 429 E+K+VDP +G T+PRG GE CTRGYSVM GYW++P+KTAE +DA WMHTGDLA M Sbjct 363 EVKIVDPVSGVTLPRGEAGELCTRGYSVMLGYWDEPEKTAESVDAGRWMHTGDLAVMRED 422 Query 430 GYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN 489 GYV+I GRIKD+++RGGEN+ PREIEE L+ HP I D V+GVPD +YGEE++A V R+ Sbjct 423 GYVQIVGRIKDMIIRGGENVYPREIEEFLYAHPKIADVQVVGVPDERYGEEILACVIPRD 482 Query 490 DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQ 538 A T+E + E+C ++A +KIPR L ++ +FPMTV+GKVRKVE+R++ Sbjct 483 PADAPTLEEITEFCREQLAHYKIPRRLEVLADFPMTVSGKVRKVELRRR 531 >gi|297156367|gb|ADI06079.1| AMP-binding domain protein [Streptomyces bingchenggensis BCW-1] Length=575 Score = 688 bits (1775), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/531 (64%), Positives = 394/531 (75%), Gaps = 2/531 (0%) Query 12 LSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLV 71 LSY G LL TIGA+LA R+ REALVD+ RR+ Y+E V +A GL+ Sbjct 21 LSYASGAGEVPLLGDTIGASLAGAIERFADREALVDLPTGRRWTYAEFGRSVEEVALGLM 80 Query 72 RAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIA 131 G+G GDRVGIWA N EWVLVQYATA IGAI+V INPA RV E+ + LRQ+G++++I+ Sbjct 81 AKGVGKGDRVGIWAVNCAEWVLVQYATARIGAIMVNINPASRVHELTFVLRQAGISVLIS 140 Query 132 VASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL--AGAEPDLPALQQTAARLDGSD 189 K ++Y M+ +V CP L DVI + WD L AGA L + ARL D Sbjct 141 STEHKTSNYRRMVEQVRSECPALRDVIYIGDRTWDGLLHAGANVSRERLIEREARLTCDD 200 Query 190 PVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNL 249 PVNIQYTSGTT +PKG TLSH NILNNGY VGE LGYT QDR+C+PVPF HCFGMV GNL Sbjct 201 PVNIQYTSGTTGFPKGATLSHHNILNNGYSVGETLGYTQQDRVCLPVPFSHCFGMVTGNL 260 Query 250 AATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTG 309 ATSHGA +VIPAP FDPAATLRAV+ ERCTSLYGVPTMFIAELGLPDF Y+L SLRTG Sbjct 261 GATSHGACIVIPAPTFDPAATLRAVEQERCTSLYGVPTMFIAELGLPDFDSYDLSSLRTG 320 Query 310 IMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHL 369 I+AG+ CPVEV+R+V+ MHM VSI YGMTETSPVSTQTR DD + R GTVGRV PHL Sbjct 321 IIAGSTCPVEVLRRVVDEMHMAEVSIFYGMTETSPVSTQTRRDDDLRHRTGTVGRVLPHL 380 Query 370 EIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPS 429 EIKVVDP TG TVPRG GE CTRGYSVM GYW +P++TAEVID WMHTGDLA MD Sbjct 381 EIKVVDPLTGVTVPRGTRGELCTRGYSVMLGYWEEPERTAEVIDGGRWMHTGDLAIMDED 440 Query 430 GYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN 489 GYVRI GRIKD+++RGGE + PREIEE L+THP I D V+GVPD KYGEE++A V LR Sbjct 441 GYVRIVGRIKDMIIRGGEKVYPREIEEFLYTHPKIADVQVVGVPDEKYGEEILACVILRE 500 Query 490 DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQAL 540 A LT + L +C GR+A +K PRYL ++D FPMTV+GKVRKVE+RQ + Sbjct 501 GAKSLTRDELARFCRGRLAHYKAPRYLRVMDAFPMTVSGKVRKVELRQAGI 551 >gi|258654979|ref|YP_003204135.1| AMP-binding domain-containing protein [Nakamurella multipartita DSM 44233] gi|258558204|gb|ACV81146.1| AMP-dependent synthetase and ligase [Nakamurella multipartita DSM 44233] Length=549 Score = 686 bits (1770), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/533 (64%), Positives = 397/533 (75%), Gaps = 2/533 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G S LL TIG L AA ALV++ RR+ Y+EL +A GL+ Sbjct 6 SYASGTSDEPLLGETIGQVLDRVAAAQPAAPALVEVGTGRRWTYAELRAAADEVALGLLA 65 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 AG+ GDRVGIWAPN EW LVQ+ +A+IGAILVTINPAYR E+ Y L Q+G+ +++A Sbjct 66 AGVRRGDRVGIWAPNLAEWTLVQFGSAKIGAILVTINPAYRSHELAYVLNQAGIGLLVAA 125 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALA--GAEPDLPALQQTAARLDGSDP 190 SFK +DYAAM+ V P+CP L V+L+ WD L G D L A L DP Sbjct 126 PSFKGSDYAAMIESVRPQCPALRRVVLIGGPEWDGLVADGRSGDPAELAHRQAELSADDP 185 Query 191 VNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLA 250 +NIQYTSGTT +PKG TLSH NI+NNGY VG L GYT DR+CIPVPFYHCFGMVMGNL Sbjct 186 INIQYTSGTTGFPKGATLSHHNIVNNGYFVGRLCGYTPADRVCIPVPFYHCFGMVMGNLG 245 Query 251 ATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGI 310 A +HGA MVIPAPGFDPAATLRAV ERCTSLYGVPTMFIAEL P F Y+L SLRTGI Sbjct 246 ALTHGATMVIPAPGFDPAATLRAVAAERCTSLYGVPTMFIAELADPGFDGYDLSSLRTGI 305 Query 311 MAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLE 370 MAG+ CPVEVM++V+ RM M V+ICYGMTETSPVSTQTRA DS++RRV TVGRV PH+E Sbjct 306 MAGSPCPVEVMKQVVQRMGMTEVTICYGMTETSPVSTQTRAGDSLERRVSTVGRVHPHVE 365 Query 371 IKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSG 430 +KV+DPATG T+PRG GE CTRGYSVM GYW++P KTA+ IDA WMHTGDLA MD G Sbjct 366 VKVIDPATGRTLPRGEPGELCTRGYSVMLGYWDEPDKTAQAIDAARWMHTGDLAAMDDEG 425 Query 431 YVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRND 490 Y+ I GRIKD+V+RGGENI PREIEE LHTHPD++D V+GVPD +YGEEL A + +R Sbjct 426 YLTITGRIKDMVIRGGENIYPREIEEFLHTHPDVLDAQVVGVPDQRYGEELCAWITMRAG 485 Query 491 APELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 AP LT E + E+ GR+A FKIPRY+ +V EFPMTVTGKVRKVEMR+++ + L Sbjct 486 APALTAEAVHEFATGRLAHFKIPRYVLVVPEFPMTVTGKVRKVEMREKSAQLL 538 >gi|337768740|emb|CCB77453.1| Acyl-CoA synthetase family member 2, mitochondrial [Streptomyces cattleya NRRL 8057] Length=544 Score = 682 bits (1761), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/529 (64%), Positives = 396/529 (75%), Gaps = 2/529 (0%) Query 12 LSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLV 71 LSY G LL+ TIG NL A + R ALVD RR++Y+ +V RLA L+ Sbjct 4 LSYAAGTGTTPLLDDTIGRNLDRAVAAWPDRPALVDAATGRRWSYAGFAAEVDRLARALL 63 Query 72 RAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIA 131 G+ GDRVGIWA N EWV QYATA IGA+LV +NPAYR E+ Y LRQSGV+++IA Sbjct 64 AYGVTKGDRVGIWAVNCPEWVFTQYATARIGAVLVNVNPAYRTHELGYVLRQSGVSLLIA 123 Query 132 VASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPA--LQQTAARLDGSD 189 ++K +DY AM A V CP L + + + W L A +PA A LD + Sbjct 124 STAYKSSDYVAMAAAVREECPGLRHTVHIGTAGWRELLAAGETVPADRTAAAQAALDCRE 183 Query 190 PVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNL 249 PVNIQYTSGTT +PKG TLSHRNILNNGY VGELLGYT DR+C+PVPFYHCFGMVMGNL Sbjct 184 PVNIQYTSGTTGFPKGATLSHRNILNNGYFVGELLGYTEADRVCLPVPFYHCFGMVMGNL 243 Query 250 AATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTG 309 AATSHGA +VIPAP FDPAATLRAV+DE CT+LYGVPTMFIAELGLPDF Y+L SLRTG Sbjct 244 AATSHGACVVIPAPVFDPAATLRAVRDEGCTALYGVPTMFIAELGLPDFAGYDLSSLRTG 303 Query 310 IMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHL 369 IMAG+ CPVEVM++V+ MHM V+ICYGMTETSPVSTQTR DD ++RR TVGRV PHL Sbjct 304 IMAGSPCPVEVMKRVVGEMHMAEVAICYGMTETSPVSTQTRRDDDLERRTATVGRVLPHL 363 Query 370 EIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPS 429 E++V DP TGETVPRGV GE TRGYSVM GYW DP++TAEVID DGWMHTGDLA M Sbjct 364 EVRVADPVTGETVPRGVPGELRTRGYSVMLGYWEDPERTAEVIDGDGWMHTGDLAVMRED 423 Query 430 GYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN 489 GY+ I GRIKD+++RGGEN+ PREIEE LHTHP I D V+GVPD +YGEE++A V R+ Sbjct 424 GYLTITGRIKDMIIRGGENVYPREIEEFLHTHPKIADVQVVGVPDERYGEEVLACVIPRD 483 Query 490 DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQ 538 A T+E + +C GR+A FKIPR LW++D FPMTV+GKVRKVE+R++ Sbjct 484 PADPPTLEEVTAHCRGRLAHFKIPRLLWVLDSFPMTVSGKVRKVELRER 532 >gi|297203377|ref|ZP_06920774.1| dicarboxylate-CoA ligase PimA [Streptomyces sviceus ATCC 29083] gi|197711466|gb|EDY55500.1| dicarboxylate-CoA ligase PimA [Streptomyces sviceus ATCC 29083] Length=528 Score = 682 bits (1760), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/526 (64%), Positives = 393/526 (75%), Gaps = 6/526 (1%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G S LL TIGANL A + REALVD+ + RR+ Y++ DV LA+ L+ Sbjct 3 SYTHGVSTTELLGDTIGANLDRAVATWPEREALVDVPSGRRWTYAQFGADVDELASALLA 62 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 +G+ GDRVGIWA N EWVLVQYATA IGAI+V INPAYR EVEY L Q+G++++ A Sbjct 63 SGVAKGDRVGIWAVNCPEWVLVQYATARIGAIMVNINPAYRTHEVEYVLNQAGISLLFAS 122 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAG-AEPDLPALQQTAARLDGSDPV 191 S K +DY AM+ EV RC +L +V+ + W AL G A PD L DP+ Sbjct 123 LSHKTSDYRAMVDEVRVRCRELREVVYIGDPSWQALLGRAVPD-----AVHPELSCDDPI 177 Query 192 NIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLAA 251 NIQYTSGTT +PKG TLSH NILNNGY VGEL+ Y+ QDRICIPVPFYHCFGMVMGNLAA Sbjct 178 NIQYTSGTTGFPKGATLSHHNILNNGYFVGELIAYSEQDRICIPVPFYHCFGMVMGNLAA 237 Query 252 TSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGIM 311 TSHGA MVIPAP FDPAATLRAVQ E CTSLYGVPTMFIAEL LPDF Y+L SLRTGIM Sbjct 238 TSHGACMVIPAPSFDPAATLRAVQQEGCTSLYGVPTMFIAELNLPDFATYDLSSLRTGIM 297 Query 312 AGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLEI 371 AG+ CPVEVM++V++ MHM VSICYGMTETSPVS QTR DD ++ R GTVGRV PH+E+ Sbjct 298 AGSPCPVEVMKRVVAEMHMAEVSICYGMTETSPVSLQTRRDDDLEHRTGTVGRVLPHIEV 357 Query 372 KVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGY 431 KVVDPATG T PRG GE CTRGYSVM GYWN+P+KTAE +D WMHTGDLA M GY Sbjct 358 KVVDPATGVTQPRGTAGELCTRGYSVMLGYWNEPEKTAEAVDQGRWMHTGDLATMREDGY 417 Query 432 VRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDA 491 V I GRIKD+++RGGENI PREIEE L+ HP I D V+GVP +YGEE++A V R+ A Sbjct 418 VEIVGRIKDMIIRGGENIYPREIEEFLYAHPKIADVQVVGVPHERYGEEVLACVIPRDPA 477 Query 492 PELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQ 537 T+E LR +C GR+A +K+P L I+D FPMTV+GKVRKVE+R+ Sbjct 478 DPPTLEELRGFCEGRLAHYKVPSRLKILDAFPMTVSGKVRKVELRE 523 >gi|291436418|ref|ZP_06575808.1| acyl-CoA synthetase [Streptomyces ghanaensis ATCC 14672] gi|291339313|gb|EFE66269.1| acyl-CoA synthetase [Streptomyces ghanaensis ATCC 14672] Length=541 Score = 680 bits (1755), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/534 (62%), Positives = 400/534 (75%), Gaps = 2/534 (0%) Query 7 VDPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRL 66 + P RLSY G S LL TIGANL A + REALVD+V+ RR+ Y+ V + Sbjct 4 LSPARLSYAHGTSTTPLLGDTIGANLDRAVAAWPDREALVDLVSGRRWTYAAFGAAVDEV 63 Query 67 ATGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGV 126 A GL+ G+ GDRVGIWA N EWVLVQYATA IG I+V INPAYR E+EY L+Q+G+ Sbjct 64 ARGLLAKGVEKGDRVGIWAVNCPEWVLVQYATARIGVIMVNINPAYRAHELEYVLKQAGI 123 Query 127 AMVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPA--LQQTAAR 184 +++++ + K +DY A++ +V +CP+L + + + WDAL +P ++ AA Sbjct 124 SVLVSSLAHKGSDYRALVEQVRGKCPELRETVFIGDPSWDALTAGAATVPQERVEAIAAG 183 Query 185 LDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGM 244 L DPVNIQYTSGTT +PKG TLSH NILNNGY VG +GYT QDR+C+PVPFYHCFGM Sbjct 184 LSCDDPVNIQYTSGTTGFPKGATLSHHNILNNGYWVGRTIGYTEQDRVCLPVPFYHCFGM 243 Query 245 VMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELG 304 VMGNLAATSHGA +VIPAP FDP ATL AVQ ERCTSLYGVPTMFIAEL LP F Y+L Sbjct 244 VMGNLAATSHGACIVIPAPSFDPEATLEAVQRERCTSLYGVPTMFIAELNLPGFARYDLT 303 Query 305 SLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGR 364 SLRTGIMAG+ CPVEVM++V++ MHM VSICYGMTETSPVS QTR DD ++ R GTVGR Sbjct 304 SLRTGIMAGSPCPVEVMKRVVAEMHMEQVSICYGMTETSPVSLQTRRDDDMEHRTGTVGR 363 Query 365 VGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLA 424 V PH+E+KVVDPATG T PRG GE CTRGYSVM GYWN+P++TAEV+DA WMHTGDLA Sbjct 364 VLPHIEVKVVDPATGTTRPRGSTGELCTRGYSVMLGYWNEPERTAEVVDAGRWMHTGDLA 423 Query 425 EMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAV 484 M GYV I GRIKD+++RGGENI PREIEE LHTHP++ D V+GVP +YGEE++A Sbjct 424 VMREDGYVEIVGRIKDMIIRGGENIYPREIEEFLHTHPEVADVQVVGVPHERYGEEVLAC 483 Query 485 VKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQ 538 V R+ A T+E LR +C R+A +K+P L I+D FPMTV+GKVRKVE+R++ Sbjct 484 VVPRDPADPPTLEDLRAFCRDRLAHYKVPSRLQILDAFPMTVSGKVRKVELRER 537 >gi|315024178|gb|ADT71659.1| putative acyl-CoA synthetase [Mycobacterium chubuense NBB4] Length=543 Score = 677 bits (1746), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/535 (63%), Positives = 395/535 (74%), Gaps = 2/535 (0%) Query 12 LSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLV 71 SY G S LL TIG NL TA + R+ALV+ RR+ Y E V +A+GL+ Sbjct 5 FSYVSGDSDVPLLRETIGENLERTARLFADRDALVECWTGRRWTYQEFARQVDAVASGLL 64 Query 72 RAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIA 131 GI GDRVGI+APN EW +QYATA++GAILV INPAYR E+EY L QSGV ++IA Sbjct 65 ETGIAKGDRVGIFAPNCAEWTFLQYATAKVGAILVNINPAYRAHELEYVLNQSGVKLLIA 124 Query 132 VASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALA--GAEPDLPALQQTAARLDGSD 189 FK +DY AM+ E+ PRC L DV++L + W+AL G D L A L D Sbjct 125 ADRFKSSDYVAMITELRPRCDALQDVVVLGGEDWEALMERGRNADPRRLLMEAELLSADD 184 Query 190 PVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNL 249 P+NIQYTSGTT +PKG TLSH+NILNNG+ VGEL GY+ DRICIPVPFYHCFGMVMGNL Sbjct 185 PINIQYTSGTTGFPKGATLSHQNILNNGFFVGELCGYSEADRICIPVPFYHCFGMVMGNL 244 Query 250 AATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTG 309 AATSHGA MVIPAP F+ TL+A++ ERCTSLYGVPTMFIAEL F D++L SLRTG Sbjct 245 AATSHGACMVIPAPSFEARTTLQAIETERCTSLYGVPTMFIAELADSAFGDFDLTSLRTG 304 Query 310 IMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHL 369 IMAG+ CPVEVM++V+ RM + ++ICYGMTETSPVS QTRADDS++RRV TVG V PHL Sbjct 305 IMAGSPCPVEVMKQVLDRMGITEITICYGMTETSPVSIQTRADDSIERRVSTVGTVHPHL 364 Query 370 EIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPS 429 EIK+VDP TG TV RG GE CTRGYSVM GYW P T+ IDA WMHTGDLA MD + Sbjct 365 EIKIVDPETGATVLRGSPGELCTRGYSVMLGYWERPDWTSGAIDAARWMHTGDLAVMDDA 424 Query 430 GYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN 489 GYV I GR KD+V+RGGEN+ PREIEE L+THP+IVD VIGVPD KYGEELMA ++++ Sbjct 425 GYVSIIGRNKDMVIRGGENLYPREIEEFLYTHPEIVDVQVIGVPDPKYGEELMAWIRMKE 484 Query 490 DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYLR 544 A LT E L +C G++A +KIPRY +VDEFPMTVTGKVRKVEMR+ A+ L+ Sbjct 485 GAQPLTREDLHGFCAGKLAHYKIPRYAHVVDEFPMTVTGKVRKVEMREIAIRLLK 539 >gi|294632131|ref|ZP_06710691.1| conserved hypothetical protein [Streptomyces sp. e14] gi|292835464|gb|EFF93813.1| conserved hypothetical protein [Streptomyces sp. e14] Length=541 Score = 676 bits (1743), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/529 (63%), Positives = 395/529 (75%), Gaps = 2/529 (0%) Query 12 LSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLV 71 +SY G S +LL TIGANL A + REALVD+ + RR+ Y++ DV RLA L+ Sbjct 1 MSYAHGTSGTTLLGDTIGANLDRAVAAWPDREALVDVPSGRRWTYADFAADVDRLARALL 60 Query 72 RAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIA 131 +G+ GDRVGIWA N EWVLVQYATA IGAI+V INPAYR EVEY L+Q+G++++ A Sbjct 61 ASGVAKGDRVGIWAVNCAEWVLVQYATARIGAIMVNINPAYRTHEVEYVLKQAGISLLFA 120 Query 132 VASFKDADYAAMLAEVGPRCPDLADVILLESDRW-DALAGAEPD-LPALQQTAARLDGSD 189 K +DY M+ +V CPDL +V+ ++ W + +A PD L AA L D Sbjct 121 SLRHKSSDYRGMIGQVRHACPDLREVVYIDDPSWTEFVARDAPDRADELLARAAELSCDD 180 Query 190 PVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNL 249 P+NIQYTSGTT +PKG TLSH NILNNGY VGEL+ Y+ QDR+C+PVPFYHCFGMVMGNL Sbjct 181 PINIQYTSGTTGFPKGATLSHHNILNNGYFVGELIAYSEQDRVCVPVPFYHCFGMVMGNL 240 Query 250 AATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTG 309 AATSHGA +V+PA FDPAATL AVQ ERCTSLYGVPTMFIAEL LP F +Y+L +LRTG Sbjct 241 AATSHGACLVVPAASFDPAATLEAVQRERCTSLYGVPTMFIAELNLPGFAEYDLSTLRTG 300 Query 310 IMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHL 369 IMAG+ CPVEVM++V++ MHM V+ICYGMTETSPVS QTR DD ++ R GTVGRV PHL Sbjct 301 IMAGSPCPVEVMKRVVAEMHMAEVAICYGMTETSPVSLQTRMDDDLEHRTGTVGRVLPHL 360 Query 370 EIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPS 429 E+KVVDPATG T PRG GE CTRGYSVM GYW P+KTAE IDA WMHTGDLA M Sbjct 361 EVKVVDPATGVTQPRGRAGELCTRGYSVMLGYWEQPEKTAEAIDAGRWMHTGDLAVMRED 420 Query 430 GYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN 489 GYV I GRIKD+++RGGENI PREIEE L+ HP I D V+GVP KYGEE++A V + Sbjct 421 GYVEIVGRIKDMIIRGGENIYPREIEEFLYAHPKIRDVQVVGVPHEKYGEEVLACVIPLD 480 Query 490 DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQ 538 A LT+E LR +C R+A +KIP L ++D FPMTV+GKVRK+E+RQ+ Sbjct 481 PADPLTLEELRAFCADRLAHYKIPSRLSVLDAFPMTVSGKVRKIELRQR 529 >gi|229492698|ref|ZP_04386499.1| acyl-CoA synthetase family member 2 [Rhodococcus erythropolis SK121] gi|229320357|gb|EEN86177.1| acyl-CoA synthetase family member 2 [Rhodococcus erythropolis SK121] Length=542 Score = 675 bits (1742), Expect = 0.0, Method: Compositional matrix adjust. Identities = 325/536 (61%), Positives = 402/536 (75%), Gaps = 4/536 (0%) Query 10 NRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATG 69 +RLS+ GP+ LLE TIG N TA R+ REA+VD+ RR+ Y+ L +V LA+ Sbjct 7 SRLSHATGPTDRLLLEMTIGDNFDHTATRFPDREAVVDLPTGRRWTYTALRAEVDALASV 66 Query 70 LVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMV 129 L+R G+ GDR+GIWAPN EW++VQYA A++GAILV +NPAYR EVE+AL Q+G+ MV Sbjct 67 LIRTGMEAGDRIGIWAPNCAEWIIVQYAAAKVGAILVNLNPAYRTHEVEFALDQAGIRMV 126 Query 130 IAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL--AGAEPDLPALQQTAARLDG 187 A+ SF+ +DYAAMLA+V PR L + +++W +L G + AL A L Sbjct 127 FALPSFRSSDYAAMLADVRPRTSALEHTVFFGTEQWASLLEQGRQISPDALANRQATLSP 186 Query 188 SDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMG 247 +DP+NIQYTSGTT +PKGVTLSHRNILNNGY VGELLGYT DR+C+PVPFYHCFGMVMG Sbjct 187 NDPINIQYTSGTTGFPKGVTLSHRNILNNGYFVGELLGYTEHDRVCLPVPFYHCFGMVMG 246 Query 248 NLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLR 307 NL AT+HGA +VIP+P FDP ATLRA DERCTSLYGVPTMFIA L + F Y+L SLR Sbjct 247 NLGATTHGACVVIPSPAFDPVATLRACADERCTSLYGVPTMFIAILNVTGFESYDLSSLR 306 Query 308 TGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGP 367 TG MAG+ CPVE+M++V +P V+I YGMTETSP S+QT DD V RR+ TVGR P Sbjct 307 TGAMAGSPCPVEIMKQVTR--WVPEVAIAYGMTETSPASSQTWVDDPVSRRISTVGRAHP 364 Query 368 HLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMD 427 H+E+K+ DP TG+T RG GE C RGYSVM GYWN+P+KTA IDADGW+H+GDLA MD Sbjct 365 HVEMKISDPVTGDTTERGQSGELCIRGYSVMLGYWNEPEKTAGAIDADGWIHSGDLAMMD 424 Query 428 PSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKL 487 G+V I GRIKD+V+RGGENI PREIEE L+THPDIVD ++GVPD KYGEELM ++L Sbjct 425 EDGFVEITGRIKDMVIRGGENIYPREIEEFLYTHPDIVDAQIVGVPDDKYGEELMVWLRL 484 Query 488 RNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 R A + + +R +C G++A +KIPRY+ VDE+PMTV+GKVRKVEMR+QA + L Sbjct 485 REGAHPIDADGIRAFCTGKLAHYKIPRYVHCVDEYPMTVSGKVRKVEMREQARQLL 540 >gi|290956371|ref|YP_003487553.1| long-chain-fatty-acid-CoA ligase [Streptomyces scabiei 87.22] gi|260645897|emb|CBG68988.1| putative long-chain-fatty-acid-CoA ligase [Streptomyces scabiei 87.22] Length=530 Score = 675 bits (1742), Expect = 0.0, Method: Compositional matrix adjust. Identities = 330/526 (63%), Positives = 387/526 (74%), Gaps = 5/526 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G SA +LL TIG NL + RE LVD+ + RR+ Y+ DV LA GL+ Sbjct 6 SYTHGTSATALLGDTIGDNLDRAVVAWPDREVLVDVPSGRRWTYARFAADVDALAYGLLA 65 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 +GI GDRVGIWA N EWVLVQYATA IGAI+V INPAYR EVEY L Q+GV ++ A Sbjct 66 SGIAKGDRVGIWAVNCPEWVLVQYATARIGAIMVNINPAYRTHEVEYVLHQAGVGLLFAS 125 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQTAARLDGSDPVN 192 S K +DY AM+ +V RCP L + + + WDAL +P + L DP+N Sbjct 126 QSHKGSDYRAMVEQVRGRCPKLRETVFIGDPGWDALIARGTPVPYEE-----LSCDDPIN 180 Query 193 IQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLAAT 252 IQYTSGTT +PKG TLSH NILNNGY VGE L YT QDRIC+PVPFYHCFGMVMGNLAAT Sbjct 181 IQYTSGTTGFPKGATLSHHNILNNGYFVGESLAYTEQDRICVPVPFYHCFGMVMGNLAAT 240 Query 253 SHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGIMA 312 SHGA +VIPAP FDP ATL AV+ ERCTSLYGVPTMFIAEL LPDF Y+L SLRTGIMA Sbjct 241 SHGACVVIPAPSFDPGATLEAVRQERCTSLYGVPTMFIAELNLPDFASYDLSSLRTGIMA 300 Query 313 GAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLEIK 372 G+ CPVEVM++V++ MHM V+ICYGMTETSPVSTQTR DD ++ R TVGRV PH+E+K Sbjct 301 GSPCPVEVMKRVVTEMHMREVAICYGMTETSPVSTQTRRDDDLEHRTATVGRVLPHIEVK 360 Query 373 VVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYV 432 VVDP TG T PRG GE CTRGYSVM GYWN+P+KTAE +DA WMHTGDLA M GYV Sbjct 361 VVDPVTGVTQPRGTAGELCTRGYSVMLGYWNEPEKTAEAVDAGRWMHTGDLATMREDGYV 420 Query 433 RIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAP 492 I GRIKD+++RGGENI PREIEE L+ HP I D V+GVP +YGEE++A V A Sbjct 421 EIVGRIKDMIIRGGENIYPREIEEFLYGHPKIADVQVVGVPHERYGEEVLACVVPHEGAE 480 Query 493 ELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQ 538 LT+E LR YC GR+A +KIP L ++D FPMTV+GKVRK+E+R++ Sbjct 481 PLTLEELRAYCEGRLAHYKIPSALRVLDSFPMTVSGKVRKIELRER 526 >gi|328886125|emb|CCA59364.1| acetoacetyl-CoA synthetase or Long-chain-fatty-acid--CoA ligase [Streptomyces venezuelae ATCC 10712] Length=534 Score = 675 bits (1742), Expect = 0.0, Method: Compositional matrix adjust. Identities = 331/528 (63%), Positives = 392/528 (75%), Gaps = 4/528 (0%) Query 10 NRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATG 69 LSY G S LL TIG NL A + REALVD+ RR+ Y++ DV RLA Sbjct 5 QELSYAHGVSETPLLGDTIGDNLDRAVAAWPDREALVDLATGRRWTYAQFGADVDRLAGS 64 Query 70 LVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMV 129 L+ +G+ GDRVGIWA N EWVLVQYATA IGA++VTINPAYR E+ Y L Q+G+ ++ Sbjct 65 LLGSGVRKGDRVGIWAVNCAEWVLVQYATARIGAVMVTINPAYRAHELAYVLNQAGITLL 124 Query 130 IAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQTAARLDGSD 189 A + K +DY AM+ +V P CP+L + + WD P + L + Sbjct 125 FASLAHKTSDYRAMVEQVRPECPELREAVYFGDLGWDVFLDRTPG----ELRPEPLSCDE 180 Query 190 PVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNL 249 PVNIQYTSGTT +PKG TLSH NILNNGY VGE++ Y+ QDRICIPVPFYHCFGMVMGNL Sbjct 181 PVNIQYTSGTTGFPKGATLSHHNILNNGYFVGEMIAYSEQDRICIPVPFYHCFGMVMGNL 240 Query 250 AATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTG 309 AATSHGA MVIPAP FDPAATLRAVQ+ERCTSLYGVPTMFIAEL LPDF Y+L SLRTG Sbjct 241 AATSHGACMVIPAPSFDPAATLRAVQEERCTSLYGVPTMFIAELNLPDFGTYDLSSLRTG 300 Query 310 IMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHL 369 IMAG+ CPVEVM++V++ M+M VSICYGMTETSPVSTQTR DD ++RR GTVGRV PH+ Sbjct 301 IMAGSPCPVEVMKRVVAEMNMAEVSICYGMTETSPVSTQTRRDDDLERRTGTVGRVMPHV 360 Query 370 EIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPS 429 E+KVVDPATG TV RG GE CTRGYSVM GYW++P+KT E IDA WMHTGDLA M Sbjct 361 EVKVVDPATGLTVARGTAGELCTRGYSVMLGYWDEPEKTGEAIDAGRWMHTGDLATMRDD 420 Query 430 GYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN 489 GYV+I GRIKD+++RGGEN+ PREIEE LH HP I D V+GVPD +YGEE++A V R+ Sbjct 421 GYVQIVGRIKDMIIRGGENVYPREIEEFLHGHPGIADVQVVGVPDERYGEEILACVIPRD 480 Query 490 DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQ 537 A T+E + +C R+A +KIPR L I+ EFPMTV+GKVRKVE+RQ Sbjct 481 PAAPPTLEDVTAFCRDRLAHYKIPRRLEILTEFPMTVSGKVRKVELRQ 528 >gi|345010053|ref|YP_004812407.1| AMP-dependent synthetase and ligase [Streptomyces violaceusniger Tu 4113] gi|344036402|gb|AEM82127.1| AMP-dependent synthetase and ligase [Streptomyces violaceusniger Tu 4113] Length=574 Score = 675 bits (1741), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/540 (62%), Positives = 397/540 (74%), Gaps = 6/540 (1%) Query 8 DPNRLSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLA 67 P LSY G LL TIGANLA YG REALVD+ + RR+ Y+E V +A Sbjct 10 SPAGLSYTSGVGDLPLLGDTIGANLARAVELYGDREALVDVPSGRRWTYAEFGRSVEEVA 69 Query 68 TGLVRAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVA 127 GL+ G+ GDRVGIWA N EWVL+QYATA IGAI+V INPAYRV E+ Y L+Q+G++ Sbjct 70 LGLMAKGVAKGDRVGIWAINCPEWVLLQYATARIGAIMVNINPAYRVHELRYVLQQAGIS 129 Query 128 MVIAVASFKDADYAAMLAEVGPRCPDLADVILLESDRWDAL----AGAEPDLPALQQTAA 183 ++++ K +DY M+ +V C L DVI + WD L AG P+ L + A Sbjct 130 VLVSSIEHKTSDYRRMVEQVRSACSSLRDVIYIGDRTWDGLVRAGAGVAPE--RLAEREA 187 Query 184 RLDGSDPVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFG 243 + D VNIQYTSGTT +PKG TLSH NILNNG+ VGE + YTA+DRIC+PVPFYHCFG Sbjct 188 LISCDDAVNIQYTSGTTGFPKGATLSHHNILNNGFFVGETVRYTAEDRICVPVPFYHCFG 247 Query 244 MVMGNLAATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYEL 303 MVMGNLAATSHGA +VIPA FDP ATL AV+ ERCTSLYGVPTMFIAEL LPDF ++L Sbjct 248 MVMGNLAATSHGACVVIPAGTFDPVATLAAVERERCTSLYGVPTMFIAELALPDFATFDL 307 Query 304 GSLRTGIMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVG 363 SLRTGIMAG+ CPVEVMR+V++ MHM VSICYGMTETSPVS QTR DD + RR TVG Sbjct 308 SSLRTGIMAGSPCPVEVMRRVVAEMHMAEVSICYGMTETSPVSAQTRPDDDLVRRTSTVG 367 Query 364 RVGPHLEIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDL 423 RV PH+E+K+VDP TG TVPRG GE CTRGYSVM GYW +P++TAE ID+ WMHTGDL Sbjct 368 RVLPHIEVKIVDPVTGATVPRGTRGELCTRGYSVMLGYWQEPERTAEAIDSARWMHTGDL 427 Query 424 AEMDPSGYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMA 483 A MD GYV+I GRIKD++VRGGEN+ PREIEE LHTHP + D V+GVPD KYGEE++A Sbjct 428 AVMDGEGYVQIVGRIKDMIVRGGENVYPREIEEFLHTHPKVADVQVVGVPDEKYGEEVLA 487 Query 484 VVKLRNDAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 V LR A LT + L +C GR+A +K+PRYL ++D FPMTV+GKVRKVE+R+ A L Sbjct 488 CVILREGAKTLTRDELARFCRGRLAHYKVPRYLRLMDGFPMTVSGKVRKVELREAAAREL 547 >gi|326331582|ref|ZP_08197872.1| substrate--CoA ligase [Nocardioidaceae bacterium Broad-1] gi|325950838|gb|EGD42888.1| substrate--CoA ligase [Nocardioidaceae bacterium Broad-1] Length=542 Score = 675 bits (1741), Expect = 0.0, Method: Compositional matrix adjust. Identities = 323/531 (61%), Positives = 390/531 (74%), Gaps = 0/531 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 S RG LLE TIGAN T AR+G REALV++ RR+ Y+ L DV LA GL + Sbjct 10 SSARGDIDVPLLEETIGANFERTVARFGDREALVEIATGRRWTYASLNADVDALAVGLRK 69 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 AGIG GDRVGIWAPN EW +VQ+ATA+IGAILV INPAYR E+ YAL QSGV ++I+ Sbjct 70 AGIGKGDRVGIWAPNCAEWTMVQFATAKIGAILVNINPAYRTHELAYALNQSGVRLLISA 129 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQTAARLDGSDPVN 192 +FK +DY A++ EV C L + L + WDAL A LD +DP+N Sbjct 130 TAFKTSDYVALVREVEGDCGALERTVFLGTPEWDALLAAGRGEQLADHVDYPLDPNDPIN 189 Query 193 IQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLAAT 252 IQYTSGTT +PKG TLSHRNILNNG+ V E + +T +DR+CIPVPFYHCFGMVM NL +T Sbjct 190 IQYTSGTTGFPKGATLSHRNILNNGFFVTETIHFTEEDRLCIPVPFYHCFGMVMANLGST 249 Query 253 SHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGIMA 312 +HGA MVIP PGFDP TL+ VQDE+CT+LYGVPTMFIA P+F ++L +LRTGIMA Sbjct 250 THGATMVIPGPGFDPRTTLQTVQDEKCTALYGVPTMFIAMQDDPEFASFDLSTLRTGIMA 309 Query 313 GAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLEIK 372 GA CP+EVM++ +S MHM V+I YGMTETSPVS QTR DD ++RR T+GR PH+EIK Sbjct 310 GALCPIEVMKRCVSEMHMSEVAIAYGMTETSPVSCQTRTDDDLERRTETIGRAAPHVEIK 369 Query 373 VVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYV 432 +VDPATG VPRG GEFCTRGYSVM GYW+D KTAE IDADGWMHTGDLA M GY Sbjct 370 IVDPATGAVVPRGTAGEFCTRGYSVMLGYWDDDTKTAEAIDADGWMHTGDLAVMREDGYC 429 Query 433 RIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAP 492 + GRIKD+V+RGGENI PREIEE L THPDI + V+GVPD +YGEEL A +++R A Sbjct 430 VVVGRIKDMVIRGGENIYPREIEEFLFTHPDIAEAQVVGVPDERYGEELCAWIRMRPGAE 489 Query 493 ELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 L +R + G++A +K PRY+ IVDEFPMTVTGKVRK++MR+Q++ L Sbjct 490 PLDAAAVRAFADGKLAHYKSPRYVLIVDEFPMTVTGKVRKIDMREQSVALL 540 >gi|271966242|ref|YP_003340438.1| AMP-dependent synthetase and ligase [Streptosporangium roseum DSM 43021] gi|270509417|gb|ACZ87695.1| AMP-dependent synthetase and ligase [Streptosporangium roseum DSM 43021] Length=530 Score = 675 bits (1741), Expect = 0.0, Method: Compositional matrix adjust. Identities = 327/531 (62%), Positives = 398/531 (75%), Gaps = 7/531 (1%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY +A LL TIG N T R+G REALVD+ + RR+ Y+EL DV+RLA L+ Sbjct 3 SYSSAAAATPLLGETIGDNFERTVRRFGDREALVDVPSGRRWTYAELDADVNRLALALLA 62 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 +GI GDR+GIWAPN EW++VQYATA+IGAILV +NPAYR E++Y +RQSG+ ++I+ Sbjct 63 SGIAKGDRIGIWAPNCAEWMIVQYATAKIGAILVNVNPAYRGHELDYVVRQSGLRLLISA 122 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQTAARLDGSDPVN 192 + K +DY AM+ E+G ADV+ L WD L L++ A L D +N Sbjct 123 LTHKGSDYRAMVEEIG-----FADVVYLGEPGWDRLLALTAPEERLRERMASLSADDAIN 177 Query 193 IQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLAAT 252 IQYTSGTT +PKG TLSH NILNNG+ VGEL+ Y DR+C+PVPFYHCFGMVMGNL AT Sbjct 178 IQYTSGTTGFPKGATLSHHNILNNGFFVGELIHYDEHDRVCLPVPFYHCFGMVMGNLGAT 237 Query 253 SHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGIMA 312 SHGA +VIPAPGFDP ATLRAVQ ERCTSLYGVPTMFIAEL L Y+L SLRTGIMA Sbjct 238 SHGACVVIPAPGFDPEATLRAVQQERCTSLYGVPTMFIAELTLAG--QYDLSSLRTGIMA 295 Query 313 GAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLEIK 372 G+ CPVEVM++V++ M+M V+ICYGMTETSPVST TR+DDS++RR TVG+V PH+E+K Sbjct 296 GSPCPVEVMKRVVTEMNMAEVAICYGMTETSPVSTMTRSDDSLERRTETVGQVMPHVEVK 355 Query 373 VVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYV 432 + P TG TVPRG GE CTRGYSVM GYWN+P++TAE ID WMHTGDLA MD GYV Sbjct 356 ITHPETGLTVPRGEPGELCTRGYSVMLGYWNEPERTAEAIDTARWMHTGDLATMDADGYV 415 Query 433 RIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAP 492 + GRIKD+V+RGGEN+ PRE+EE L+ HPDI D VIGVPD KYGEELMA V +R Sbjct 416 NVVGRIKDMVIRGGENVYPREVEEFLYRHPDIADVQVIGVPDEKYGEELMAWVVIRQGGT 475 Query 493 ELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQALEYL 543 LT E +RE+C G++A +KIPRY+ +VD FPMTVTGK+RKVEMR++ + L Sbjct 476 PLTAEAVREFCAGKLAHYKIPRYVHVVDGFPMTVTGKIRKVEMREEGVRLL 526 >gi|302557512|ref|ZP_07309854.1| substrate-CoA ligase [Streptomyces griseoflavus Tu4000] gi|302475130|gb|EFL38223.1| substrate-CoA ligase [Streptomyces griseoflavus Tu4000] Length=538 Score = 674 bits (1740), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/529 (63%), Positives = 396/529 (75%), Gaps = 2/529 (0%) Query 12 LSYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLV 71 LSY G LL TIGANLA T A + REALVD+ + RR+ Y+E V +A GL+ Sbjct 5 LSYAHGTGTTPLLGDTIGANLARTVAAWPDREALVDVASGRRWTYAEFGAAVDEVARGLL 64 Query 72 RAGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIA 131 GI GDRVGIWA N EWVLVQYATA IG I+V INPAYR E+EY L+QSG++++++ Sbjct 65 AKGITTGDRVGIWAVNCPEWVLVQYATARIGVIMVNINPAYRAHELEYVLKQSGISLLVS 124 Query 132 VASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQ--QTAARLDGSD 189 + K +DY A++ +V CPDL + + + WDAL GA +P + + AA L D Sbjct 125 SLAHKGSDYRALVEQVRGACPDLRETVYIGDPSWDALTGAAAAVPPERPDEIAAGLSCDD 184 Query 190 PVNIQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNL 249 PVNIQYTSGTT +PKG TLSH NILNNGY VG +GYT +DR+C+PVPFYHCFGMVMGNL Sbjct 185 PVNIQYTSGTTGFPKGATLSHHNILNNGYWVGRTVGYTERDRVCLPVPFYHCFGMVMGNL 244 Query 250 AATSHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTG 309 AATSHGA +V+PAP FDPAATL AVQ ERCTSLYGVPTMFIAEL LP F Y+L SLRTG Sbjct 245 AATSHGACIVVPAPSFDPAATLEAVQRERCTSLYGVPTMFIAELNLPGFASYDLTSLRTG 304 Query 310 IMAGAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHL 369 IMAG+ CPVEVM++V++ MHM VSICYGMTETSPVS QTR DD ++ R GTVGRV PH+ Sbjct 305 IMAGSPCPVEVMKRVVAEMHMEQVSICYGMTETSPVSLQTRMDDDLEHRTGTVGRVLPHI 364 Query 370 EIKVVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPS 429 E+KVVDPATG T+PRG GE CTRGYSVM GYWN+P+KTAE +DA WMHTGDLA M Sbjct 365 EVKVVDPATGVTLPRGAAGELCTRGYSVMLGYWNEPEKTAEAVDAGRWMHTGDLAVMRED 424 Query 430 GYVRIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRN 489 GYV I GRIKD+++RGGENI PREIEE L+ HP I D V+G +YGEE++A V R+ Sbjct 425 GYVEIVGRIKDMIIRGGENIYPREIEEFLYAHPKIADIQVVGTAHERYGEEVLACVVPRD 484 Query 490 DAPELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQ 538 A T+E LR +C R+A +KIP L ++D FPMTV+GKVRKVE+R++ Sbjct 485 PADPPTLEELRAFCADRLAHYKIPSRLQLLDTFPMTVSGKVRKVELRER 533 >gi|302555107|ref|ZP_07307449.1| dicarboxylate-CoA ligase PimA [Streptomyces viridochromogenes DSM 40736] gi|302472725|gb|EFL35818.1| dicarboxylate-CoA ligase PimA [Streptomyces viridochromogenes DSM 40736] Length=529 Score = 672 bits (1733), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/526 (63%), Positives = 391/526 (75%), Gaps = 5/526 (0%) Query 13 SYDRGPSAPSLLESTIGANLAATAARYGHREALVDMVARRRFNYSELLTDVHRLATGLVR 72 SY G LL TIGANL A + REALVD+ + RR+ Y+ DV LA L+ Sbjct 3 SYSHGTGPTPLLGDTIGANLDRAVAAWPDREALVDVPSGRRWTYARFAADVDELAYALLA 62 Query 73 AGIGPGDRVGIWAPNRWEWVLVQYATAEIGAILVTINPAYRVREVEYALRQSGVAMVIAV 132 +G+ GDRVGIWA N EWVLVQYATA IGAI+V INPAYR EVEY L+Q+GV+++ A Sbjct 63 SGVAKGDRVGIWAVNCPEWVLVQYATARIGAIMVNINPAYRTHEVEYVLKQAGVSLLFAS 122 Query 133 ASFKDADYAAMLAEVGPRCPDLADVILLESDRWDALAGAEPDLPALQQTAARLDGSDPVN 192 +S + +DY AM+ +V RCP L + + + W+AL +P + L DP+N Sbjct 123 SSHRTSDYRAMVEQVRGRCPRLRETVFIGDPGWEALIARGTPVPFEE-----LSCDDPIN 177 Query 193 IQYTSGTTAYPKGVTLSHRNILNNGYLVGELLGYTAQDRICIPVPFYHCFGMVMGNLAAT 252 IQYTSGTT +PKG TLSH NILNNGY VGEL+ YT QDRIC+PVPFYHCFGMVMGNLAAT Sbjct 178 IQYTSGTTGFPKGATLSHHNILNNGYFVGELIAYTEQDRICVPVPFYHCFGMVMGNLAAT 237 Query 253 SHGAAMVIPAPGFDPAATLRAVQDERCTSLYGVPTMFIAELGLPDFTDYELGSLRTGIMA 312 SHGA +VIPAP FDP ATL AVQ ERCTSLYGVPTMFIAEL LPDF Y+L SLRTGIMA Sbjct 238 SHGACIVIPAPSFDPKATLDAVQRERCTSLYGVPTMFIAELNLPDFASYDLSSLRTGIMA 297 Query 313 GAACPVEVMRKVISRMHMPGVSICYGMTETSPVSTQTRADDSVDRRVGTVGRVGPHLEIK 372 G+ CPVEVM++V++ MHM VSICYGMTETSPVS QTR DD ++ R GTVGRV PH+E+K Sbjct 298 GSPCPVEVMKRVVAEMHMAEVSICYGMTETSPVSLQTRRDDDLEHRTGTVGRVLPHIEVK 357 Query 373 VVDPATGETVPRGVVGEFCTRGYSVMAGYWNDPQKTAEVIDADGWMHTGDLAEMDPSGYV 432 VVDPATG T PRG GE CTRGYSVM GYW++P+KTAE +DA WMHTGDLA M GYV Sbjct 358 VVDPATGVTQPRGTAGELCTRGYSVMLGYWDEPEKTAEAVDAGRWMHTGDLATMREDGYV 417 Query 433 RIAGRIKDLVVRGGENISPREIEELLHTHPDIVDGHVIGVPDAKYGEELMAVVKLRNDAP 492 I GRIKD+++RGGENI PREIEE L+ HP I D ++GVP YGEE++A V R+ A Sbjct 418 EIVGRIKDMIIRGGENIYPREIEEFLYAHPGIQDVQIVGVPHEHYGEEVLACVIARDPAD 477 Query 493 ELTIERLREYCMGRIARFKIPRYLWIVDEFPMTVTGKVRKVEMRQQ 538 T+E LR +C GR+A +KIP L ++D FPMTV+GKVRKVE+R++ Sbjct 478 PPTLEGLRAFCEGRLAHYKIPSRLQLLDTFPMTVSGKVRKVELRER 523 Lambda K H 0.320 0.137 0.415 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1210654467756 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40