BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2506

Length=215
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15842034|ref|NP_337071.1|  TetR family transcriptional regulat...   424    4e-117
gi|15609643|ref|NP_217022.1|  TetR family transcriptional regulat...   422    2e-116
gi|254232635|ref|ZP_04925962.1|  hypothetical protein TBCG_02446 ...   421    5e-116
gi|306793987|ref|ZP_07432289.1|  transcriptional regulator, tetR-...   419    1e-115
gi|289570666|ref|ZP_06450893.1|  transcriptional regulator, tetR-...   395    2e-108
gi|308379223|ref|ZP_07485551.2|  transcriptional regulator, tetR-...   379    2e-103
gi|308369736|ref|ZP_07418882.2|  transcriptional regulator, tetR-...   376    1e-102
gi|240171588|ref|ZP_04750247.1|  putative transcriptional regulat...   360    9e-98 
gi|183983828|ref|YP_001852119.1|  putative regulatory protein [My...   336    2e-90 
gi|296170425|ref|ZP_06852013.1|  TetR family transcriptional regu...   335    3e-90 
gi|118619028|ref|YP_907360.1|  putative regulatory protein [Mycob...   334    5e-90 
gi|254823122|ref|ZP_05228123.1|  hypothetical protein MintA_24550...   333    7e-90 
gi|254774495|ref|ZP_05216011.1|  hypothetical protein MaviaA2_074...   330    1e-88 
gi|41408413|ref|NP_961249.1|  hypothetical protein MAP2315 [Mycob...   327    7e-88 
gi|342857894|ref|ZP_08714550.1|  TetR family transcriptional regu...   311    3e-83 
gi|118462743|ref|YP_880901.1|  TetR family transcriptional regula...   311    6e-83 
gi|333990039|ref|YP_004522653.1|  regulatory protein [Mycobacteri...   295    2e-78 
gi|126436214|ref|YP_001071905.1|  TetR family transcriptional reg...   285    3e-75 
gi|108800598|ref|YP_640795.1|  TetR family transcriptional regula...   285    4e-75 
gi|145223138|ref|YP_001133816.1|  TetR family transcriptional reg...   273    1e-71 
gi|118472914|ref|YP_888978.1|  TetR family transcriptional regula...   271    6e-71 
gi|120405046|ref|YP_954875.1|  TetR family transcriptional regula...   268    3e-70 
gi|226305318|ref|YP_002765276.1|  TetR family transcriptional reg...   246    2e-63 
gi|111023057|ref|YP_706029.1|  TetR family transcriptional regula...   239    2e-61 
gi|226365560|ref|YP_002783343.1|  TetR family transcriptional reg...   237    1e-60 
gi|333922017|ref|YP_004495598.1|  putative TetR family transcript...   229    2e-58 
gi|312140937|ref|YP_004008273.1|  tetr family transcriptional reg...   226    2e-57 
gi|325675425|ref|ZP_08155109.1|  TetR family transcriptional regu...   226    3e-57 
gi|54027010|ref|YP_121252.1|  putative transcriptional regulator ...   203    2e-50 
gi|309812420|ref|ZP_07706175.1|  transcriptional regulator, TetR ...   197    7e-49 
gi|331699875|ref|YP_004336114.1|  regulatory protein TetR [Pseudo...   192    2e-47 
gi|169631615|ref|YP_001705264.1|  TetR family transcriptional reg...   187    1e-45 
gi|88855169|ref|ZP_01129834.1|  hypothetical protein A20C1_04786 ...   184    6e-45 
gi|111222574|ref|YP_713368.1|  TetR family transcriptional regula...   184    8e-45 
gi|312199560|ref|YP_004019621.1|  TetR family transcriptional reg...   181    4e-44 
gi|116669945|ref|YP_830878.1|  TetR family transcriptional regula...   179    3e-43 
gi|320010675|gb|ADW05525.1|  regulatory protein TetR [Streptomyce...   178    5e-43 
gi|220912172|ref|YP_002487481.1|  TetR family transcriptional reg...   174    6e-42 
gi|325962777|ref|YP_004240683.1|  TetR family transcriptional reg...   174    8e-42 
gi|325000907|ref|ZP_08122019.1|  TetR family transcriptional regu...   173    1e-41 
gi|182438553|ref|YP_001826272.1|  TetR family transcriptional reg...   172    2e-41 
gi|163839307|ref|YP_001623712.1|  TetR family transcriptional reg...   171    4e-41 
gi|239987889|ref|ZP_04708553.1|  TetR family transcriptional regu...   171    4e-41 
gi|290960186|ref|YP_003491368.1|  TetR family transcriptional reg...   171    6e-41 
gi|344999846|ref|YP_004802700.1|  TetR family transcriptional reg...   171    9e-41 
gi|345015342|ref|YP_004817696.1|  regulatory protein TetR [Strept...   170    1e-40 
gi|289771485|ref|ZP_06530863.1|  TetR family transcriptional regu...   170    1e-40 
gi|302545218|ref|ZP_07297560.1|  TetR family transcriptional regu...   170    2e-40 
gi|302560532|ref|ZP_07312874.1|  TetR family transcriptional regu...   169    2e-40 
gi|297160331|gb|ADI10043.1|  TetR family transcriptional regulato...   169    3e-40 


>gi|15842034|ref|NP_337071.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
CDC1551]
 gi|13882312|gb|AAK46885.1| transcriptional regulator, TetR family [Mycobacterium tuberculosis 
CDC1551]
Length=231

 Score =  424 bits (1091),  Expect = 4e-117, Method: Compositional matrix adjust.
 Identities = 215/215 (100%), Positives = 215/215 (100%), Gaps = 0/215 (0%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP
Sbjct  17   VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  76

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI
Sbjct  77   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  136

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP
Sbjct  137  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  196

Query  181  HSMKAADSKPARTVRARAVLRAMTVAALSAADRCL  215
            HSMKAADSKPARTVRARAVLRAMTVAALSAADRCL
Sbjct  197  HSMKAADSKPARTVRARAVLRAMTVAALSAADRCL  231


>gi|15609643|ref|NP_217022.1| TetR family transcriptional regulator [Mycobacterium tuberculosis 
H37Rv]
 gi|31793686|ref|NP_856179.1| TetR family transcriptional regulator [Mycobacterium bovis AF2122/97]
 gi|121638388|ref|YP_978612.1| TetR family transcriptional regulator [Mycobacterium bovis BCG 
str. Pasteur 1173P2]
 52 more sequence titles
 Length=215

 Score =  422 bits (1085),  Expect = 2e-116, Method: Compositional matrix adjust.
 Identities = 214/215 (99%), Positives = 215/215 (100%), Gaps = 0/215 (0%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            +TASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP
Sbjct  1    MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI
Sbjct  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP
Sbjct  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180

Query  181  HSMKAADSKPARTVRARAVLRAMTVAALSAADRCL  215
            HSMKAADSKPARTVRARAVLRAMTVAALSAADRCL
Sbjct  181  HSMKAADSKPARTVRARAVLRAMTVAALSAADRCL  215


>gi|254232635|ref|ZP_04925962.1| hypothetical protein TBCG_02446 [Mycobacterium tuberculosis C]
 gi|124601694|gb|EAY60704.1| hypothetical protein TBCG_02446 [Mycobacterium tuberculosis C]
Length=215

 Score =  421 bits (1081),  Expect = 5e-116, Method: Compositional matrix adjust.
 Identities = 213/215 (99%), Positives = 215/215 (100%), Gaps = 0/215 (0%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            +TASAP+GRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP
Sbjct  1    MTASAPNGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI
Sbjct  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP
Sbjct  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180

Query  181  HSMKAADSKPARTVRARAVLRAMTVAALSAADRCL  215
            HSMKAADSKPARTVRARAVLRAMTVAALSAADRCL
Sbjct  181  HSMKAADSKPARTVRARAVLRAMTVAALSAADRCL  215


>gi|306793987|ref|ZP_07432289.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu005]
 gi|308337677|gb|EFP26528.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu005]
Length=215

 Score =  419 bits (1077),  Expect = 1e-115, Method: Compositional matrix adjust.
 Identities = 213/215 (99%), Positives = 214/215 (99%), Gaps = 0/215 (0%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            +TASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP
Sbjct  1    MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI
Sbjct  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP
Sbjct  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180

Query  181  HSMKAADSKPARTVRARAVLRAMTVAALSAADRCL  215
            H MKAADSKPARTVRARAVLRAMTVAALSAADRCL
Sbjct  181  HRMKAADSKPARTVRARAVLRAMTVAALSAADRCL  215


>gi|289570666|ref|ZP_06450893.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
T17]
 gi|289544420|gb|EFD48068.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
T17]
Length=201

 Score =  395 bits (1015),  Expect = 2e-108, Method: Compositional matrix adjust.
 Identities = 200/201 (99%), Positives = 201/201 (100%), Gaps = 0/201 (0%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            +TASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP
Sbjct  1    MTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI
Sbjct  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP
Sbjct  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180

Query  181  HSMKAADSKPARTVRARAVLR  201
            HSMKAADSKPARTVRARAVLR
Sbjct  181  HSMKAADSKPARTVRARAVLR  201


>gi|308379223|ref|ZP_07485551.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu010]
 gi|308380386|ref|ZP_07489773.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu011]
 gi|308357717|gb|EFP46568.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu010]
 gi|308361657|gb|EFP50508.1| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu011]
Length=194

 Score =  379 bits (973),  Expect = 2e-103, Method: Compositional matrix adjust.
 Identities = 193/194 (99%), Positives = 194/194 (100%), Gaps = 0/194 (0%)

Query  22   LKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVS  81
            +KSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVS
Sbjct  1    MKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVS  60

Query  82   ARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA  141
            ARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA
Sbjct  61   ARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA  120

Query  142  QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR  201
            QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR
Sbjct  121  QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR  180

Query  202  AMTVAALSAADRCL  215
            AMTVAALSAADRCL
Sbjct  181  AMTVAALSAADRCL  194


>gi|308369736|ref|ZP_07418882.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu002]
 gi|308371035|ref|ZP_07423628.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu003]
 gi|308372251|ref|ZP_07427982.2| transcriptional regulator, tetR-family [Mycobacterium tuberculosis 
SUMu004]
 11 more sequence titles
 Length=194

 Score =  376 bits (966),  Expect = 1e-102, Method: Compositional matrix adjust.
 Identities = 192/194 (99%), Positives = 193/194 (99%), Gaps = 0/194 (0%)

Query  22   LKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVS  81
            +KSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVS
Sbjct  1    MKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVS  60

Query  82   ARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA  141
            ARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA
Sbjct  61   ARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA  120

Query  142  QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR  201
            QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPH MKAADSKPARTVRARAVLR
Sbjct  121  QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHRMKAADSKPARTVRARAVLR  180

Query  202  AMTVAALSAADRCL  215
            AMTVAALSAADRCL
Sbjct  181  AMTVAALSAADRCL  194


>gi|240171588|ref|ZP_04750247.1| putative transcriptional regulatory protein [Mycobacterium kansasii 
ATCC 12478]
Length=213

 Score =  360 bits (923),  Expect = 9e-98, Method: Compositional matrix adjust.
 Identities = 178/212 (84%), Positives = 196/212 (93%), Gaps = 0/212 (0%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            +TASAPDGRP QPEA++RRSQLKSDRR QLL+AAERLFAERGFLAVRLEDIGA AG+SGP
Sbjct  1    MTASAPDGRPAQPEASSRRSQLKSDRRLQLLSAAERLFAERGFLAVRLEDIGAVAGISGP  60

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVG+S+RLLAGARDVT R ++ AAALDGLI+FHLDFALGE DLI
Sbjct  61   AIYRHFPNKESLLVELLVGISSRLLAGARDVTARGSDPAAALDGLIDFHLDFALGEPDLI  120

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDLAHLPA AERQVRKAQRQYVEVWVGVLRE +P LAEADARLMAHAVFGLLNSTP
Sbjct  121  RIQDRDLAHLPAAAERQVRKAQRQYVEVWVGVLRERDPDLAEADARLMAHAVFGLLNSTP  180

Query  181  HSMKAADSKPARTVRARAVLRAMTVAALSAAD  212
            HSMK+AD++ AR +R+R ++RAMTVAAL   D
Sbjct  181  HSMKSADARSARVLRSRTIMRAMTVAALRVTD  212


>gi|183983828|ref|YP_001852119.1| putative regulatory protein [Mycobacterium marinum M]
 gi|183177154|gb|ACC42264.1| conserved hypothetical regulatory protein [Mycobacterium marinum 
M]
Length=211

 Score =  336 bits (861),  Expect = 2e-90, Method: Compositional matrix adjust.
 Identities = 170/209 (82%), Positives = 186/209 (89%), Gaps = 3/209 (1%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            + ASAPD +   P   NRRSQ KSDRR QLL+AAERLFAERGFLAVRLEDIGAAAG+SGP
Sbjct  1    MAASAPDEQTATP---NRRSQQKSDRRLQLLSAAERLFAERGFLAVRLEDIGAAAGISGP  57

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVG+S+RLLAGAR VTT S + AAALDGLI+FHLDFALGE DLI
Sbjct  58   AIYRHFPNKESLLVELLVGISSRLLAGARQVTTNSNDAAAALDGLIDFHLDFALGEPDLI  117

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDL HLPA AERQVRKAQRQYVE+WVGVLR+L+PGLAEADARLMAHA FGLLNSTP
Sbjct  118  RIQDRDLGHLPAAAERQVRKAQRQYVEIWVGVLRQLDPGLAEADARLMAHAAFGLLNSTP  177

Query  181  HSMKAADSKPARTVRARAVLRAMTVAALS  209
            HSMK+AD+K A    +RAV+RAMTVAAL+
Sbjct  178  HSMKSADTKSACAPHSRAVMRAMTVAALT  206


>gi|296170425|ref|ZP_06852013.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295894896|gb|EFG74617.1| TetR family transcriptional regulator [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=219

 Score =  335 bits (859),  Expect = 3e-90, Method: Compositional matrix adjust.
 Identities = 177/218 (82%), Positives = 190/218 (88%), Gaps = 4/218 (1%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            +T S  DGRPG  +  NRRSQLKSDRR QLL+AAERLFAERGFLAVRLEDIGAAAGVSGP
Sbjct  1    MTTSTSDGRPGPADTPNRRSQLKSDRRLQLLSAAERLFAERGFLAVRLEDIGAAAGVSGP  60

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDV-TTRSANLAAALDGLIEFHLDFALGEADL  119
            AIYRHFPNKESLLVELLVG+SARLLAGARDV    S + AAALDGLI+FHLDFALGE DL
Sbjct  61   AIYRHFPNKESLLVELLVGISARLLAGARDVRAHSSDDAAAALDGLIDFHLDFALGEPDL  120

Query  120  IRIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNST  179
            IRIQDRDLAHLP  AE+QVRKAQRQYVEVWVGVLRELNP LAEADARL AHAVFGLLNST
Sbjct  121  IRIQDRDLAHLPEAAEKQVRKAQRQYVEVWVGVLRELNPDLAEADARLTAHAVFGLLNST  180

Query  180  PHSMKAAD---SKPARTVRARAVLRAMTVAALSAADRC  214
            P+SMK+ D   SK AR  R+RAV+RAMTVAAL+A + C
Sbjct  181  PYSMKSPDTSRSKSARAARSRAVMRAMTVAALAAGNEC  218


>gi|118619028|ref|YP_907360.1| putative regulatory protein [Mycobacterium ulcerans Agy99]
 gi|118571138|gb|ABL05889.1| conserved hypothetical regulatory protein [Mycobacterium ulcerans 
Agy99]
Length=211

 Score =  334 bits (857),  Expect = 5e-90, Method: Compositional matrix adjust.
 Identities = 169/209 (81%), Positives = 186/209 (89%), Gaps = 3/209 (1%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            + ASAPD +   P   NRRSQ KSDRR QLL+AAERLFAERGFLAVRLEDIGAAAG+SGP
Sbjct  1    MAASAPDEQTATP---NRRSQQKSDRRLQLLSAAERLFAERGFLAVRLEDIGAAAGISGP  57

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVG+S+RLLAGAR VTT S + AAALDGLI+FHLDFALGE DLI
Sbjct  58   AIYRHFPNKESLLVELLVGISSRLLAGARQVTTNSNDAAAALDGLIDFHLDFALGEPDLI  117

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDL HLPA AERQVRKAQRQYVE+WVGVLR+L+PGLAEADARLMAHA FGLLNSTP
Sbjct  118  RIQDRDLGHLPAAAERQVRKAQRQYVEIWVGVLRQLDPGLAEADARLMAHAAFGLLNSTP  177

Query  181  HSMKAADSKPARTVRARAVLRAMTVAALS  209
            HSM++AD+K A    +RAV+RAMTVAAL+
Sbjct  178  HSMESADTKSACAPHSRAVMRAMTVAALT  206


>gi|254823122|ref|ZP_05228123.1| hypothetical protein MintA_24550 [Mycobacterium intracellulare 
ATCC 13950]
Length=218

 Score =  333 bits (855),  Expect = 7e-90, Method: Compositional matrix adjust.
 Identities = 170/217 (79%), Positives = 186/217 (86%), Gaps = 3/217 (1%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            +T S  DG     EA NRRSQLKSDRR QLL+AAERLFAERGFLAVRLEDIGAAAGVSGP
Sbjct  1    MTTSTSDGHAAGAEAPNRRSQLKSDRRLQLLSAAERLFAERGFLAVRLEDIGAAAGVSGP  60

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVG+S RLLAGAR V  R+++ +AALDGLI+FHLDFAL E DLI
Sbjct  61   AIYRHFPNKESLLVELLVGISTRLLAGARQVRARNSDASAALDGLIDFHLDFALTEPDLI  120

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDLA+LP  AE+QVRKAQRQYVEVWVGVLRELNP LAE DARL AHAVFGLLNSTP
Sbjct  121  RIQDRDLAYLPGAAEKQVRKAQRQYVEVWVGVLRELNPELAETDARLTAHAVFGLLNSTP  180

Query  181  HSMKAAD---SKPARTVRARAVLRAMTVAALSAADRC  214
            HSMK+ D   SK AR  R+RAV+RAMT+AAL A ++C
Sbjct  181  HSMKSPDTSRSKGARAARSRAVMRAMTIAALEAGNQC  217


>gi|254774495|ref|ZP_05216011.1| hypothetical protein MaviaA2_07468 [Mycobacterium avium subsp. 
avium ATCC 25291]
 gi|336460989|gb|EGO39869.1| transcriptional regulator [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=218

 Score =  330 bits (845),  Expect = 1e-88, Method: Compositional matrix adjust.
 Identities = 174/217 (81%), Positives = 190/217 (88%), Gaps = 3/217 (1%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            +T SA + R G  +  NRRSQLKSDRR QLL+AAERLFAERGFLAVRLEDIGA+AGVSGP
Sbjct  1    MTTSASESRAGGAQPPNRRSQLKSDRRLQLLSAAERLFAERGFLAVRLEDIGASAGVSGP  60

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVG+S RLLAGAR V  RSA+ AAALDGLI+FHLDFAL E DLI
Sbjct  61   AIYRHFPNKESLLVELLVGISTRLLAGARQVRARSADAAAALDGLIDFHLDFALNEPDLI  120

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDLA+LP  AERQVRKAQRQYVEVWVGVLRELNP LAEADARL AHAVFGLLNSTP
Sbjct  121  RIQDRDLAYLPKPAERQVRKAQRQYVEVWVGVLRELNPELAEADARLTAHAVFGLLNSTP  180

Query  181  HSMKAADS---KPARTVRARAVLRAMTVAALSAADRC  214
            HSMK+ DS   KPAR  R+RA++RAMTVAAL+A ++C
Sbjct  181  HSMKSQDSGRGKPARAARSRAIMRAMTVAALAAGNQC  217


>gi|41408413|ref|NP_961249.1| hypothetical protein MAP2315 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41396769|gb|AAS04632.1| hypothetical protein MAP_2315 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=218

 Score =  327 bits (838),  Expect = 7e-88, Method: Compositional matrix adjust.
 Identities = 173/217 (80%), Positives = 189/217 (88%), Gaps = 3/217 (1%)

Query  1    VTASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGP  60
            +T SA + R G  +  NRRSQLKSDRR QLL+AAERLFAERGFLAVRLEDIGA+AGVSGP
Sbjct  1    MTTSASESRAGGAQPPNRRSQLKSDRRLQLLSAAERLFAERGFLAVRLEDIGASAGVSGP  60

Query  61   AIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLI  120
            AIYRHFPNKESLLVELLVG+S RLLAGAR V  RSA+ AAALDGLI+FHLDFAL E DLI
Sbjct  61   AIYRHFPNKESLLVELLVGISTRLLAGARQVRARSADAAAALDGLIDFHLDFALNEPDLI  120

Query  121  RIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTP  180
            RIQDRDLA+LP  AERQVRKAQRQYVEVWVGVLRELNP LAEADARL AHAVFGLLNSTP
Sbjct  121  RIQDRDLAYLPKPAERQVRKAQRQYVEVWVGVLRELNPELAEADARLTAHAVFGLLNSTP  180

Query  181  HSMKAADS---KPARTVRARAVLRAMTVAALSAADRC  214
            HSMK+  S   KPAR  R+RA++RAMTVAAL+A ++C
Sbjct  181  HSMKSQGSGRGKPARAARSRAIMRAMTVAALAAGNQC  217


>gi|342857894|ref|ZP_08714550.1| TetR family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
 gi|342135227|gb|EGT88393.1| TetR family transcriptional regulator [Mycobacterium colombiense 
CECT 3035]
Length=197

 Score =  311 bits (798),  Expect = 3e-83, Method: Compositional matrix adjust.
 Identities = 158/196 (81%), Positives = 174/196 (89%), Gaps = 3/196 (1%)

Query  22   LKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVS  81
            +KSDRR QLL+AAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVG+S
Sbjct  1    MKSDRRLQLLSAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGIS  60

Query  82   ARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA  141
             RLLAGAR V   S + AAALDGLI+FHLDF   E DLIRIQDRDLA+LPA AE+QVRK+
Sbjct  61   TRLLAGARQVQAGSRDAAAALDGLIDFHLDFVFNEPDLIRIQDRDLAYLPAAAEKQVRKS  120

Query  142  QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRA---RA  198
            QRQYVEVWVGVLRELNP LAEADARL AHAVFGLLNSTPHSMK+ D+  ++TVRA   RA
Sbjct  121  QRQYVEVWVGVLRELNPELAEADARLAAHAVFGLLNSTPHSMKSPDTSRSKTVRAARSRA  180

Query  199  VLRAMTVAALSAADRC  214
            V+RAMTVAAL+A ++C
Sbjct  181  VMRAMTVAALAAGNQC  196


>gi|118462743|ref|YP_880901.1| TetR family transcriptional regulator [Mycobacterium avium 104]
 gi|118164030|gb|ABK64927.1| transcriptional regulator, TetR family protein [Mycobacterium 
avium 104]
Length=197

 Score =  311 bits (796),  Expect = 6e-83, Method: Compositional matrix adjust.
 Identities = 163/196 (84%), Positives = 177/196 (91%), Gaps = 3/196 (1%)

Query  22   LKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVS  81
            +KSDRR QLL+AAERLFAERGFLAVRLEDIGA+AGVSGPAIYRHFPNKESLLVELLVG+S
Sbjct  1    MKSDRRLQLLSAAERLFAERGFLAVRLEDIGASAGVSGPAIYRHFPNKESLLVELLVGIS  60

Query  82   ARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA  141
             RLLAGAR V  RSA+ AAALDGLI+FHLDFAL E DLIRIQDRDLA+LP  AERQVRKA
Sbjct  61   TRLLAGARQVRARSADAAAALDGLIDFHLDFALNEPDLIRIQDRDLAYLPKPAERQVRKA  120

Query  142  QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADS---KPARTVRARA  198
            QRQYVEVWVGVLRELNP LAEADARL AHAVFGLLNSTPHSMK+ DS   KPAR  R+RA
Sbjct  121  QRQYVEVWVGVLRELNPELAEADARLTAHAVFGLLNSTPHSMKSQDSGRGKPARAARSRA  180

Query  199  VLRAMTVAALSAADRC  214
            ++RAMTVAAL+A ++C
Sbjct  181  IMRAMTVAALAAGNQC  196


>gi|333990039|ref|YP_004522653.1| regulatory protein [Mycobacterium sp. JDM601]
 gi|333486007|gb|AEF35399.1| putative regulatory protein [Mycobacterium sp. JDM601]
Length=216

 Score =  295 bits (756),  Expect = 2e-78, Method: Compositional matrix adjust.
 Identities = 156/198 (79%), Positives = 170/198 (86%), Gaps = 0/198 (0%)

Query  14   EATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLL  73
            E  NRRS+LKSDRR QLL AAERLFA+RGFLAVRLEDIGAAAGVSGPAIYRHF NKE+LL
Sbjct  14   EPANRRSRLKSDRRSQLLTAAERLFAQRGFLAVRLEDIGAAAGVSGPAIYRHFANKEALL  73

Query  74   VELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAV  133
            VELLVG+S RLLAGAR V +   +  A LDGLIEFHLDFALGE DLIRIQDRDLAHLPA 
Sbjct  74   VELLVGISTRLLAGARAVESGGRSPDAVLDGLIEFHLDFALGEPDLIRIQDRDLAHLPAG  133

Query  134  AERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPART  193
            A+RQVR AQRQYVEVWVGVL   + GLAEADARLMAHAVFGLLNSTP+S+K A +K A  
Sbjct  134  AQRQVRSAQRQYVEVWVGVLCARHAGLAEADARLMAHAVFGLLNSTPYSVKPAGAKSAAP  193

Query  194  VRARAVLRAMTVAALSAA  211
             R+RAVLRAMT++AL AA
Sbjct  194  ERSRAVLRAMTISALGAA  211


>gi|126436214|ref|YP_001071905.1| TetR family transcriptional regulator [Mycobacterium sp. JLS]
 gi|126236014|gb|ABN99414.1| transcriptional regulator, TetR family [Mycobacterium sp. JLS]
Length=207

 Score =  285 bits (730),  Expect = 3e-75, Method: Compositional matrix adjust.
 Identities = 145/200 (73%), Positives = 168/200 (84%), Gaps = 1/200 (0%)

Query  15   ATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLV  74
            A+ RRS+ KSDRR QL+AAAERL AE+G+LAVRLEDIG+A GVSGPAIYRHFPNKE++LV
Sbjct  7    ASTRRSRAKSDRRSQLIAAAERLVAEKGYLAVRLEDIGSAVGVSGPAIYRHFPNKEAMLV  66

Query  75   ELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVA  134
            ELLVG+S RLLAGAR+V T S +   ALDGLI+FHLDFALGE+DLIRIQDRDL HLP  A
Sbjct  67   ELLVGISTRLLAGAREVLTDSPDAETALDGLIDFHLDFALGESDLIRIQDRDLGHLPDPA  126

Query  135  ERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTV  194
            +RQVR+AQRQYVE+WV VLR ++P L EA ARLMAHA FGLLNSTPHS+K   +K A   
Sbjct  127  KRQVRRAQRQYVEIWVEVLRAVDPSLDEAQARLMAHAAFGLLNSTPHSVKPGATKTAEA-  185

Query  195  RARAVLRAMTVAALSAADRC  214
             +R VLRAMTVAAL++A R 
Sbjct  186  SSRTVLRAMTVAALASAGRL  205


>gi|108800598|ref|YP_640795.1| TetR family transcriptional regulator [Mycobacterium sp. MCS]
 gi|119869737|ref|YP_939689.1| TetR family transcriptional regulator [Mycobacterium sp. KMS]
 gi|108771017|gb|ABG09739.1| transcriptional regulator, TetR family [Mycobacterium sp. MCS]
 gi|119695826|gb|ABL92899.1| transcriptional regulator, TetR family [Mycobacterium sp. KMS]
Length=207

 Score =  285 bits (728),  Expect = 4e-75, Method: Compositional matrix adjust.
 Identities = 145/200 (73%), Positives = 167/200 (84%), Gaps = 1/200 (0%)

Query  15   ATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLV  74
            A+ RRS+ KSDRR QL+AAAERL AE+G+LAVRLEDIG+A GVSGPAIYRHFPNKE++LV
Sbjct  7    ASTRRSRAKSDRRSQLIAAAERLVAEKGYLAVRLEDIGSAVGVSGPAIYRHFPNKEAMLV  66

Query  75   ELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVA  134
            ELLVG+S RLLAGAR+V T S +   ALDGLI+FHLDFALGE+DLIRIQDRDL HLP  A
Sbjct  67   ELLVGISTRLLAGAREVLTDSPDAETALDGLIDFHLDFALGESDLIRIQDRDLGHLPDPA  126

Query  135  ERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTV  194
            +RQVR+AQRQYVE+WV VLR ++P L EA ARLMAHA FGLLNSTPHS+K   SK A   
Sbjct  127  KRQVRRAQRQYVEIWVEVLRAVDPSLDEAQARLMAHAAFGLLNSTPHSVKPGASKTAEA-  185

Query  195  RARAVLRAMTVAALSAADRC  214
             +R  LRAMTVAAL++A R 
Sbjct  186  SSRTALRAMTVAALASAGRL  205


>gi|145223138|ref|YP_001133816.1| TetR family transcriptional regulator [Mycobacterium gilvum PYR-GCK]
 gi|315443595|ref|YP_004076474.1| TetR family transcriptional regulator [Mycobacterium sp. Spyr1]
 gi|145215624|gb|ABP45028.1| transcriptional regulator, TetR family [Mycobacterium gilvum 
PYR-GCK]
 gi|315261898|gb|ADT98639.1| transcriptional regulator, TetR family [Mycobacterium sp. Spyr1]
Length=206

 Score =  273 bits (698),  Expect = 1e-71, Method: Compositional matrix adjust.
 Identities = 138/200 (69%), Positives = 163/200 (82%), Gaps = 1/200 (0%)

Query  14   EATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLL  73
            E ++ RS+ KSDRR QL+AAAERLFAE G+LAVRLEDIG+AAG+SGPA+YRHFPNKE+LL
Sbjct  5    EISSPRSRAKSDRRDQLVAAAERLFAEHGYLAVRLEDIGSAAGISGPAVYRHFPNKEALL  64

Query  74   VELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAV  133
            VELLVG+S RLLAGA DV     + A+ L+ LI+FHLDFAL E+DLIRIQDRDL +LP  
Sbjct  65   VELLVGISTRLLAGATDVVGADDDAASTLENLIDFHLDFALDESDLIRIQDRDLGNLPPA  124

Query  134  AERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPART  193
            A+RQVR+ QRQYVE+WV VLR   PGL+EADARLMAH  FGLLNST HSMK   +K A  
Sbjct  125  AKRQVRRKQRQYVEIWVDVLRRCTPGLSEADARLMAHGTFGLLNSTAHSMKPGTTKTAE-  183

Query  194  VRARAVLRAMTVAALSAADR  213
              +R VLR MTVAAL++A+R
Sbjct  184  AGSRTVLREMTVAALTSAER  203


>gi|118472914|ref|YP_888978.1| TetR family transcriptional regulator [Mycobacterium smegmatis 
str. MC2 155]
 gi|118174201|gb|ABK75097.1| transcriptional regulator, TetR family protein [Mycobacterium 
smegmatis str. MC2 155]
Length=201

 Score =  271 bits (692),  Expect = 6e-71, Method: Compositional matrix adjust.
 Identities = 138/197 (71%), Positives = 160/197 (82%), Gaps = 1/197 (0%)

Query  15   ATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLV  74
            +  RRSQ KSDRR QL+AAAERL AERG+LAVRLEDIGAA GVSGPAIYRHFPNKE++LV
Sbjct  3    SVTRRSQAKSDRRSQLIAAAERLVAERGYLAVRLEDIGAAVGVSGPAIYRHFPNKEAMLV  62

Query  75   ELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVA  134
            ELLVG+S RLL GAR+V     + A ALD L++FHLDFA  E+DLIRIQDRDLAHLP  A
Sbjct  63   ELLVGISTRLLDGAREVVETHDDPAKALDALVDFHLDFAFDESDLIRIQDRDLAHLPDTA  122

Query  135  ERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSK-PART  193
            +RQVR+AQRQYVE+WV VL  L   L E +AR+MAHA FGLLNSTPHS+K A +K  + T
Sbjct  123  KRQVRRAQRQYVEIWVSVLTRLRRDLPEEEARVMAHATFGLLNSTPHSVKPAVTKAQSST  182

Query  194  VRARAVLRAMTVAALSA  210
             ++R VLR MTVAAL+A
Sbjct  183  AQSRGVLRRMTVAALTA  199


>gi|120405046|ref|YP_954875.1| TetR family transcriptional regulator [Mycobacterium vanbaalenii 
PYR-1]
 gi|119957864|gb|ABM14869.1| transcriptional regulator, TetR family [Mycobacterium vanbaalenii 
PYR-1]
Length=206

 Score =  268 bits (686),  Expect = 3e-70, Method: Compositional matrix adjust.
 Identities = 139/201 (70%), Positives = 162/201 (81%), Gaps = 2/201 (0%)

Query  14   EATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLL  73
            +AT+ RS+ KSDRR QL+ AAERL AE G+LAVRLEDIGAAAG+SGPAIYRHFPNKE+LL
Sbjct  5    DATSPRSRAKSDRRGQLIGAAERLIAEHGYLAVRLEDIGAAAGISGPAIYRHFPNKEALL  64

Query  74   VELLVGVSARLLAGARDVTTRSANLA-AALDGLIEFHLDFALGEADLIRIQDRDLAHLPA  132
            VELLVG+S RLLAGA +V  R+ + A +AL+GLI+FHLDF  GE DLIRIQDRDL +LP 
Sbjct  65   VELLVGISTRLLAGAVEVVDRAGDDADSALEGLIDFHLDFVFGEPDLIRIQDRDLGNLPP  124

Query  133  VAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPAR  192
             A+RQVR+ QRQYVE+WV VLR   PGL E DARLMAHA FGLLNSTPH +K   +K A 
Sbjct  125  AAKRQVRRKQRQYVEIWVDVLRRRTPGLTETDARLMAHAAFGLLNSTPHGVKPGLNKAAE  184

Query  193  TVRARAVLRAMTVAALSAADR  213
               +R VLR MTVAAL++A R
Sbjct  185  -ASSRTVLRTMTVAALTSAGR  204


>gi|226305318|ref|YP_002765276.1| TetR family transcriptional regulator [Rhodococcus erythropolis 
PR4]
 gi|229490636|ref|ZP_04384474.1| transcriptional regulator, TetR family [Rhodococcus erythropolis 
SK121]
 gi|226184433|dbj|BAH32537.1| putative TetR family transcriptional regulator [Rhodococcus erythropolis 
PR4]
 gi|229322456|gb|EEN88239.1| transcriptional regulator, TetR family [Rhodococcus erythropolis 
SK121]
Length=199

 Score =  246 bits (627),  Expect = 2e-63, Method: Compositional matrix adjust.
 Identities = 128/197 (65%), Positives = 152/197 (78%), Gaps = 5/197 (2%)

Query  12   QPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKES  71
            Q  A  RR Q+K+DRR QLL AA RL AERGF++VRLED+GAA G+SGPA+YRHFPNK++
Sbjct  5    QVAAPTRRDQMKADRRRQLLDAAARLIAERGFVSVRLEDLGAAVGISGPAVYRHFPNKDA  64

Query  72   LLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLP  131
            +LVELLVG+S RL  G       + + +AALD L+EFHLDFALGE DLIRIQDRDL  LP
Sbjct  65   VLVELLVGISTRLHEGGSAAAEAADSPSAALDALVEFHLDFALGEPDLIRIQDRDLESLP  124

Query  132  AVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPA  191
            A A RQVR+ QR+YVEVWVGVL +L+P L +ADAR+ AHA FGL+NSTPHS     + PA
Sbjct  125  ADARRQVRQTQRKYVEVWVGVLEQLDPQLDQADARIKAHATFGLINSTPHS-----ANPA  179

Query  192  RTVRARAVLRAMTVAAL  208
               RAR VLR MT+AAL
Sbjct  180  SPARARRVLRDMTLAAL  196


>gi|111023057|ref|YP_706029.1| TetR family transcriptional regulator [Rhodococcus jostii RHA1]
 gi|110822587|gb|ABG97871.1| possible transcriptional regulator, TetR family protein [Rhodococcus 
jostii RHA1]
Length=212

 Score =  239 bits (611),  Expect = 2e-61, Method: Compositional matrix adjust.
 Identities = 124/198 (63%), Positives = 149/198 (76%), Gaps = 5/198 (2%)

Query  11   GQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKE  70
            G      RR Q+K+DRR QLL AA RL AERGFL VRLED+G+AAG+SGPA+YRHFPNK+
Sbjct  18   GTEAPITRREQMKADRRRQLLDAAARLIAERGFLGVRLEDLGSAAGISGPAVYRHFPNKD  77

Query  71   SLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHL  130
            ++LVELLVG+S RLL G   V   +A+  AAL+GLI+FHLDFALGE DLIRIQDRDL  L
Sbjct  78   AVLVELLVGISTRLLEGGSLVVAEAASPEAALEGLIDFHLDFALGEPDLIRIQDRDLESL  137

Query  131  PAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKP  190
            PA A R+VR+ QR+YVE+WV VL +++  L E DAR  AHA FGL+NSTPHS  A  + P
Sbjct  138  PAEARREVRQTQRRYVEIWVKVLLQVDTSLDETDARTKAHATFGLINSTPHS--ADPTTP  195

Query  191  ARTVRARAVLRAMTVAAL  208
            +RT   R VLR MT+  L
Sbjct  196  SRT---RKVLRDMTLLCL  210


>gi|226365560|ref|YP_002783343.1| TetR family transcriptional regulator [Rhodococcus opacus B4]
 gi|226244050|dbj|BAH54398.1| putative TetR family transcriptional regulator [Rhodococcus opacus 
B4]
Length=213

 Score =  237 bits (604),  Expect = 1e-60, Method: Compositional matrix adjust.
 Identities = 122/202 (61%), Positives = 146/202 (73%), Gaps = 10/202 (4%)

Query  7    DGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHF  66
            DG P       RR Q+K+DRR QLL AA RL AERGFL VRLED+G+AAG+SGPA+YRHF
Sbjct  16   DGAP-----ITRREQMKADRRRQLLDAAARLIAERGFLGVRLEDLGSAAGISGPAVYRHF  70

Query  67   PNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRD  126
            PNK+++LVELLVG+S RL  G   V   + +  AAL+GLI+FHLDFALGE DLIRIQDRD
Sbjct  71   PNKDAVLVELLVGISTRLFEGGSLVAAEATSPDAALEGLIDFHLDFALGEPDLIRIQDRD  130

Query  127  LAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAA  186
            L  LP  A R+VR+ QR+YVE+WV VL +++  L E DAR  AHA FGL+NSTPHS    
Sbjct  131  LESLPVDARREVRQTQRRYVEIWVKVLLQVDSSLDETDARTKAHATFGLINSTPHS----  186

Query  187  DSKPARTVRARAVLRAMTVAAL  208
             + PA   R R VLR MT + L
Sbjct  187  -ADPATPSRTRKVLRDMTFSCL  207


>gi|333922017|ref|YP_004495598.1| putative TetR family transcriptional regulator [Amycolicicoccus 
subflavus DQS3-9A1]
 gi|333484238|gb|AEF42798.1| Putative TetR family transcriptional regulator [Amycolicicoccus 
subflavus DQS3-9A1]
Length=200

 Score =  229 bits (584),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 122/199 (62%), Positives = 145/199 (73%), Gaps = 6/199 (3%)

Query  12   QPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKES  71
            Q  A  RRSQ+K+DRR QLL+AA +L AERG+  VRLEDIGA  G+SGPAIYRHFPNKE+
Sbjct  8    QDAAPTRRSQMKADRRKQLLSAAAKLIAERGYNGVRLEDIGAEVGISGPAIYRHFPNKEA  67

Query  72   LLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLP  131
            LLVELL GVS  LL G  +V   +++  AAL GLIEFHLDFA+ ++DLIR+QDRDL  LP
Sbjct  68   LLVELLTGVSDHLLYGGTEVADNASDAEAALAGLIEFHLDFAINQSDLIRVQDRDLHSLP  127

Query  132  AVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPA  191
              A+ QVR  QR+YVE WV VL +LNP L    AR  AHAVFGL+NSTPHS +A    PA
Sbjct  128  REAQHQVRMMQRRYVERWVQVLMDLNPDLDAVSARTKAHAVFGLINSTPHSARA----PA  183

Query  192  RTVRARAVLRAMTVAALSA  210
               R R +LR M  AAL++
Sbjct  184  --ARTRELLRNMAKAALAS  200


>gi|312140937|ref|YP_004008273.1| tetr family transcriptional regulator [Rhodococcus equi 103S]
 gi|311890276|emb|CBH49594.1| putative TetR family transcriptional regulator [Rhodococcus equi 
103S]
Length=209

 Score =  226 bits (576),  Expect = 2e-57, Method: Compositional matrix adjust.
 Identities = 117/197 (60%), Positives = 146/197 (75%), Gaps = 0/197 (0%)

Query  17   NRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVEL  76
             RRS+ K+DRR +LL AA RL AERGF  VRLED+G+A G+SGPA+YRHFPNK++LLVEL
Sbjct  13   GRRSRAKADRRRELLRAAARLIAERGFPGVRLEDLGSAVGISGPAVYRHFPNKDALLVEL  72

Query  77   LVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAER  136
            L  +S RLLAG  DV  R  +   AL  L++FHLDFALGE DLIR+QDRDL  LP  A  
Sbjct  73   LTDISERLLAGGTDVVERVPDPHRALAELVDFHLDFALGEPDLIRVQDRDLHSLPDDARH  132

Query  137  QVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRA  196
            +VR+ QR+YVE+WVGVLR+++PGL    AR+ AHA FGL+NSTP+S  +  +  A     
Sbjct  133  RVRQTQRRYVELWVGVLRKMDPGLDSTQARIAAHAAFGLINSTPYSAVSPTADAADGDLT  192

Query  197  RAVLRAMTVAALSAADR  213
            R+VLR MT+AAL+A  R
Sbjct  193  RSVLRRMTLAALAAETR  209


>gi|325675425|ref|ZP_08155109.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 
33707]
 gi|325553396|gb|EGD23074.1| TetR family transcriptional regulator [Rhodococcus equi ATCC 
33707]
Length=209

 Score =  226 bits (575),  Expect = 3e-57, Method: Compositional matrix adjust.
 Identities = 116/197 (59%), Positives = 146/197 (75%), Gaps = 0/197 (0%)

Query  17   NRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVEL  76
             RRS+ K+DRR +LL AA RL AERGF  VRLED+G+A G+SGPA+YRHFPNK++LLVEL
Sbjct  13   GRRSRAKADRRRELLRAAARLIAERGFPGVRLEDLGSAVGISGPAVYRHFPNKDALLVEL  72

Query  77   LVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAER  136
            L  +S RLLAG  DV  R  +   AL  L++FHLDFALGE DLIR+QDRDL  LP  A  
Sbjct  73   LTDISERLLAGGTDVVERVPDPHRALAELVDFHLDFALGEPDLIRVQDRDLHSLPDEARH  132

Query  137  QVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRA  196
            +VR+ QR+YVE+WVGVLR+++PGL    AR+ AHA FGL+NSTP+S  +  +  A     
Sbjct  133  RVRQTQRRYVELWVGVLRKMDPGLDSTQARIAAHAAFGLINSTPYSAVSPTADAADGDLT  192

Query  197  RAVLRAMTVAALSAADR  213
            R+VLR MT+AA++A  R
Sbjct  193  RSVLRRMTLAAIAAETR  209


>gi|54027010|ref|YP_121252.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]
 gi|54018518|dbj|BAD59888.1| putative transcriptional regulator [Nocardia farcinica IFM 10152]
Length=209

 Score =  203 bits (516),  Expect = 2e-50, Method: Compositional matrix adjust.
 Identities = 114/194 (59%), Positives = 145/194 (75%), Gaps = 7/194 (3%)

Query  17   NRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVEL  76
             RR QLK++RR +LL A  RL A+RGFL VRL+D+GAA G+SGPA+YRHFP+KE+LLVEL
Sbjct  17   TRREQLKAERRRRLLEAGARLIADRGFLGVRLDDLGAAVGISGPAVYRHFPSKEALLVEL  76

Query  77   LVGVSARLLAGARDVTTR--SANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVA  134
            LVGVS RLL G R V       +  + + GL++FHLDFALGE +LIRIQDRDL  +P  A
Sbjct  77   LVGVSERLLDGGRAVLADHDGGDPRSVIAGLVDFHLDFALGEPELIRIQDRDLDQMPDDA  136

Query  135  ERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTV  194
             R+VR+ QRQYVE+WV  L+ ++P L+E +AR+ AHAVFGL+NSTPHS  A+D++     
Sbjct  137  RRRVRRTQRQYVELWVDALQRVHPQLSEGEARVRAHAVFGLMNSTPHSATASDAE-----  191

Query  195  RARAVLRAMTVAAL  208
            R R  LR M +AAL
Sbjct  192  RVRPALREMALAAL  205


>gi|309812420|ref|ZP_07706175.1| transcriptional regulator, TetR family [Dermacoccus sp. Ellin185]
 gi|308433725|gb|EFP57602.1| transcriptional regulator, TetR family [Dermacoccus sp. Ellin185]
Length=208

 Score =  197 bits (502),  Expect = 7e-49, Method: Compositional matrix adjust.
 Identities = 105/191 (55%), Positives = 135/191 (71%), Gaps = 1/191 (0%)

Query  19   RSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLV  78
            R + K+ RR Q+L AA  L AERG   VRLED+G+A G+SGPA+YRHF NKE++L ELLV
Sbjct  14   RERSKAARRQQILDAAAGLIAERGLAGVRLEDLGSAVGISGPAVYRHFANKEAVLAELLV  73

Query  79   GVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQV  138
            G+S  LL     V   +A    AL+ L++FH+DF+L +  LIR+Q RDLA L A A R V
Sbjct  74   GISRYLLENGSRVVADAATADEALENLVDFHIDFSLTKPALIRVQGRDLASLDAAARRDV  133

Query  139  RKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSM-KAADSKPARTVRAR  197
            R+ QRQYVE+WVGVLR+++P L++ +AR+ AHA FG LNSTPHS  +   +  A   R R
Sbjct  134  RQLQRQYVEIWVGVLRDVDPSLSDDEARIKAHAGFGALNSTPHSTGRTKTAVEAHRERTR  193

Query  198  AVLRAMTVAAL  208
            AVLRAM +AAL
Sbjct  194  AVLRAMALAAL  204


>gi|331699875|ref|YP_004336114.1| regulatory protein TetR [Pseudonocardia dioxanivorans CB1190]
 gi|326954564|gb|AEA28261.1| regulatory protein TetR [Pseudonocardia dioxanivorans CB1190]
Length=194

 Score =  192 bits (489),  Expect = 2e-47, Method: Compositional matrix adjust.
 Identities = 100/186 (54%), Positives = 124/186 (67%), Gaps = 5/186 (2%)

Query  24   SDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSAR  83
            + RR Q+L  A RLFA  GF  V + D+GAA GVSGPA+YRHFP KE+LL E+LVG+S  
Sbjct  9    TGRREQILTVAARLFARHGFHGVSIADLGAAVGVSGPALYRHFPGKEALLAEMLVGISEH  68

Query  84   LLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQR  143
            LLAG R+  T   +  A L+ L++FHLDFAL   DLI +QDRDLA+LP    R+VR  QR
Sbjct  69   LLAGGRERATVDGDARATLEALVDFHLDFALTSPDLIVVQDRDLANLPPEPRRRVRLLQR  128

Query  144  QYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLRAM  203
             YVE+WV VLRE+ PGL    AR+ AH  FGLLNSTPHS     ++        A+LR M
Sbjct  129  TYVEIWVDVLREITPGLTPEAARIAAHGAFGLLNSTPHSGARGSTR-----EVAALLRGM  183

Query  204  TVAALS  209
             + AL+
Sbjct  184  ALTALT  189


>gi|169631615|ref|YP_001705264.1| TetR family transcriptional regulator [Mycobacterium abscessus 
ATCC 19977]
 gi|169243582|emb|CAM64610.1| Putative transcriptional regulator, TetR family [Mycobacterium 
abscessus]
Length=200

 Score =  187 bits (474),  Expect = 1e-45, Method: Compositional matrix adjust.
 Identities = 120/197 (61%), Positives = 144/197 (74%), Gaps = 5/197 (2%)

Query  12   QPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKES  71
            + E  N+R + K+DRR QLL AA RL A RG+  VRLED+G+A G+SGPAIYRHFPNKE+
Sbjct  7    ESETPNKRERAKADRRDQLLRAAARLLAMRGYARVRLEDLGSAVGISGPAIYRHFPNKEA  66

Query  72   LLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLP  131
            LLV+LL  VS RLL G   V   +++ A ALDGLI+FHLDFAL E+DLIR+QDRDL  LP
Sbjct  67   LLVDLLTDVSRRLLEGGMTVAAAASSPAEALDGLIDFHLDFALNESDLIRVQDRDLDSLP  126

Query  132  AVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPA  191
              A RQVR+ QR+YVE WV VL     GL E+DAR+ AHA FGL+NSTP+S  A  S P+
Sbjct  127  ENARRQVRQYQRRYVEAWVQVLCRSQQGLDESDARIKAHAAFGLMNSTPYS--AGRSAPS  184

Query  192  RTVRARAVLRAMTVAAL  208
            +T   R VLR M VAAL
Sbjct  185  QT---RTVLRQMVVAAL  198


>gi|88855169|ref|ZP_01129834.1| hypothetical protein A20C1_04786 [marine actinobacterium PHSC20C1]
 gi|88815697|gb|EAR25554.1| hypothetical protein A20C1_04786 [marine actinobacterium PHSC20C1]
Length=191

 Score =  184 bits (468),  Expect = 6e-45, Method: Compositional matrix adjust.
 Identities = 103/197 (53%), Positives = 127/197 (65%), Gaps = 8/197 (4%)

Query  14   EATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLL  73
            E    RSQ K+DRR  LL AA  LFAERGF  V LED+G+AAG+SGPA+YRHF  K+ +L
Sbjct  3    ETPTPRSQAKADRRQALLDAAASLFAERGFTRVSLEDLGSAAGISGPAVYRHFDGKQDVL  62

Query  74   VELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAV  133
              +LV  S  L  GA+ V   +A   AAL+ LIEFH++FALG  ++IR+QDRDL  L   
Sbjct  63   AAMLVDTSTDLCTGAKTVIESAATPRAALESLIEFHVEFALGNPNVIRVQDRDLDSLTDD  122

Query  134  AERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPART  193
             +  VR  QR YVE+WV  L +L+P  A  + R  AHA FGL+NSTPHS + ADS     
Sbjct  123  DKHTVRALQRSYVELWVSTLAQLHPDAATTELRTRAHATFGLINSTPHSGR-ADST----  177

Query  194  VRARAVLRAMTVAALSA  210
               RAVL  M +AAL A
Sbjct  178  ---RAVLERMALAALDA  191


>gi|111222574|ref|YP_713368.1| TetR family transcriptional regulator [Frankia alni ACN14a]
 gi|111150106|emb|CAJ61801.1| putative TetR family transcriptional regulator (partial match) 
[Frankia alni ACN14a]
Length=281

 Score =  184 bits (467),  Expect = 8e-45, Method: Compositional matrix adjust.
 Identities = 95/165 (58%), Positives = 116/165 (71%), Gaps = 0/165 (0%)

Query  23   KSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSA  82
            +S RR  LL AA RLFAERGF  V +E IGAA G+ GP IYRHF +K+++L ELLVG+S 
Sbjct  99   RSGRRDDLLQAAARLFAERGFRGVGIEQIGAAVGIRGPGIYRHFASKDAMLTELLVGISQ  158

Query  83   RLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQ  142
             LL GA+ V +   + A ALD L+  H++FA+G  DLI I DRDL  LPA  E +VR+ Q
Sbjct  159  HLLHGAQTVLSADPSAADALDRLVRRHVEFAVGNPDLIVIHDRDLHSLPAPDEHEVRRLQ  218

Query  143  RQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAAD  187
            R YVE+WVGVLR L P L    AR+ AHA+FGL+NSTPHS  A D
Sbjct  219  RAYVELWVGVLRRLRPELTAPAARVRAHAIFGLINSTPHSSGALD  263


>gi|312199560|ref|YP_004019621.1| TetR family transcriptional regulator [Frankia sp. EuI1c]
 gi|311230896|gb|ADP83751.1| regulatory protein TetR [Frankia sp. EuI1c]
Length=237

 Score =  181 bits (460),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 109/206 (53%), Positives = 134/206 (66%), Gaps = 7/206 (3%)

Query  10   PGQPEA--TNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFP  67
            PG P A      S     RR QLL AA RL A+RG+  V + DIGAAAGVSGPA+Y+HFP
Sbjct  34   PGPPAALPVTTPSAPAGARREQLLGAAARLMADRGYHGVSINDIGAAAGVSGPAVYKHFP  93

Query  68   NKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDL  127
            +K+++L ELLVG+S RLLA      T +A+   ALD L+ +H+ FALG  +LIRIQDRDL
Sbjct  94   SKQAILTELLVGISERLLAEGTVRATAAADPDEALDALVRWHVSFALGSPELIRIQDRDL  153

Query  128  AHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAAD  187
            A +   A R VR+ QR+YVE+WV  LR  +P LAE  AR   HA FGLLNSTP+S   A 
Sbjct  154  ASMDETAARLVRRLQRRYVELWVAQLRARDPELAEDAARATVHATFGLLNSTPYS---AT  210

Query  188  SKPARTVRARA--VLRAMTVAALSAA  211
               AR  RAR   +L  + +AAL AA
Sbjct  211  GGAARLGRARMADLLHRLGLAALRAA  236


>gi|116669945|ref|YP_830878.1| TetR family transcriptional regulator [Arthrobacter sp. FB24]
 gi|116610054|gb|ABK02778.1| transcriptional regulator, TetR family [Arthrobacter sp. FB24]
Length=225

 Score =  179 bits (454),  Expect = 3e-43, Method: Compositional matrix adjust.
 Identities = 103/209 (50%), Positives = 137/209 (66%), Gaps = 4/209 (1%)

Query  3    ASAPDGRPGQ---PEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSG  59
            A +P G+  Q   P  T +RSQ K  RR  LL++A  LFA  GF  V LED+GAAAGVSG
Sbjct  8    AGSPAGQRAQTTLPVQTTQRSQAKESRRQALLSSAATLFALNGFNRVSLEDLGAAAGVSG  67

Query  60   PAIYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADL  119
            PA+YRHF  K+++L  LL+ VS  LL G R V   + + AAAL  L++FH+DFAL   D+
Sbjct  68   PAVYRHFAGKQAVLGALLLSVSQELLDGGRRVVADAGDPAAALARLVQFHVDFALSNPDV  127

Query  120  IRIQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNST  179
            IR+QDRD ++L    +  VR  QR YVE+WV VL+ L+ G   A+ R+ AHA FGL+NST
Sbjct  128  IRVQDRDFSNLSDDDQAAVRTLQRNYVELWVEVLQALHAGTDTAELRMRAHAAFGLINST  187

Query  180  PHSMKAADSKPARTVRARAVLRAMTVAAL  208
            PHS+++   + A    AR +L +M +AAL
Sbjct  188  PHSVRSHGRRVA-AKSARPLLESMALAAL  215


>gi|320010675|gb|ADW05525.1| regulatory protein TetR [Streptomyces flavogriseus ATCC 33331]
Length=204

 Score =  178 bits (451),  Expect = 5e-43, Method: Compositional matrix adjust.
 Identities = 101/191 (53%), Positives = 128/191 (68%), Gaps = 7/191 (3%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+L  A RLFAERGF  V +++IGAA G+SGP +YRHFP K+++L ELLVG+S RLL
Sbjct  14   RREQILREAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFPGKDAMLAELLVGISERLL  73

Query  86   AGAR-----DVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRK  140
            AG R     D  +R  +  A LD LIE H+DFAL +  LI + DR+L  L     ++VR+
Sbjct  74   AGGRLRVSEDGASRGGSPDALLDALIEGHIDFALDDRPLITLHDRELDRLRDTDRKRVRQ  133

Query  141  AQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVL  200
             QRQYVEVWV V+R L P LAE +AR+  HAVFGLLNSTPH +   ++ P RT  A A+L
Sbjct  134  LQRQYVEVWVDVVRALYPALAENEARVTVHAVFGLLNSTPH-LTRPEALPDRTATA-ALL  191

Query  201  RAMTVAALSAA  211
              +   A  AA
Sbjct  192  HRLARGAFEAA  202


>gi|220912172|ref|YP_002487481.1| TetR family transcriptional regulator [Arthrobacter chlorophenolicus 
A6]
 gi|219859050|gb|ACL39392.1| transcriptional regulator, TetR family [Arthrobacter chlorophenolicus 
A6]
Length=220

 Score =  174 bits (442),  Expect = 6e-42, Method: Compositional matrix adjust.
 Identities = 104/208 (50%), Positives = 137/208 (66%), Gaps = 2/208 (0%)

Query  2    TASAPDGRPGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPA  61
             ++  D    +P    +RS+ K DRR  LLAAA  LFA  GF +V LED+GAAAGVSGPA
Sbjct  8    NSTGTDAPAARPAGATQRSKAKEDRRQALLAAAASLFAVNGFKSVSLEDLGAAAGVSGPA  67

Query  62   IYRHFPNKESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIR  121
            +YRHFP K+++L +LL  VS  LL G R V   +A+   AL  L+EF +DFALG+ ++IR
Sbjct  68   VYRHFPGKQAVLADLLATVSRELLDGGRKVVAENADPRLALRRLVEFQVDFALGKPEVIR  127

Query  122  IQDRDLAHLPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPH  181
            +QDRDL++L    +  VR  QR YVEVWV VL  L+PG   A+ R  AHA FGL+NSTPH
Sbjct  128  VQDRDLSNLSEQDQSAVRALQRSYVEVWVDVLSRLHPGTDAAELRTRAHATFGLINSTPH  187

Query  182  SMKAADSKPARTVRARAVLRAMTVAALS  209
            S+++   + A    AR +L  M +AAL+
Sbjct  188  SVRSHGRRMA--AAARPLLEEMALAALT  213


>gi|325962777|ref|YP_004240683.1| TetR family transcriptional regulator [Arthrobacter phenanthrenivorans 
Sphe3]
 gi|323468864|gb|ADX72549.1| transcriptional regulator, TetR family [Arthrobacter phenanthrenivorans 
Sphe3]
Length=244

 Score =  174 bits (441),  Expect = 8e-42, Method: Compositional matrix adjust.
 Identities = 102/192 (54%), Positives = 131/192 (69%), Gaps = 1/192 (0%)

Query  17   NRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVEL  76
             +RS+ K  RR  LLAAA  LFA  GF  V LED+GAAAGVSGPA+YRHFP K+++L +L
Sbjct  43   TQRSRAKESRRQALLAAAASLFALHGFNRVSLEDLGAAAGVSGPAVYRHFPGKQAVLADL  102

Query  77   LVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAER  136
            LV VS  LL G R V + + +  AAL  L++F +DFALG+ D+IR+QDRD + L    + 
Sbjct  103  LVTVSQELLDGGRRVVSENPDPLAALQRLVQFQVDFALGKPDVIRVQDRDFSSLSDQDQA  162

Query  137  QVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRA  196
             VR  QR YVEVWV VL  L+PG   ++ R+ AHA FGL+NSTPHS+++   K A T  A
Sbjct  163  AVRALQRSYVEVWVDVLARLHPGTDSSELRMRAHATFGLINSTPHSVRSHGRKIA-TGTA  221

Query  197  RAVLRAMTVAAL  208
            R +L  M +AAL
Sbjct  222  RPLLEGMALAAL  233


>gi|325000907|ref|ZP_08122019.1| TetR family transcriptional regulator [Pseudonocardia sp. P1]
Length=172

 Score =  173 bits (439),  Expect = 1e-41, Method: Compositional matrix adjust.
 Identities = 88/159 (56%), Positives = 115/159 (73%), Gaps = 1/159 (0%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+LA A RLFA  GF  V + D+GAA GVSGPA+YRHFP KE+LL E+L+ +S RLL
Sbjct  11   RREQILAEAARLFARHGFHGVSIADLGAAVGVSGPALYRHFPGKEALLAEMLIDISERLL  70

Query  86   AGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQRQY  145
             G R    R  +  AAL  L++FH++FA  E +LI +QDRDLA+LP  A R VR+ QR Y
Sbjct  71   EGGR-ARVRHDDPRAALADLVDFHVEFATREPELIVVQDRDLANLPDEARRTVRRLQRTY  129

Query  146  VEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMK  184
            VE+WV  LR ++PG+  ++AR +AH VFGLLNSTP++ +
Sbjct  130  VELWVDTLRRVHPGVPPSEARTVAHGVFGLLNSTPYAPR  168


>gi|182438553|ref|YP_001826272.1| TetR family transcriptional regulator [Streptomyces griseus subsp. 
griseus NBRC 13350]
 gi|326779200|ref|ZP_08238465.1| regulatory protein TetR [Streptomyces cf. griseus XylebKG-1]
 gi|178467069|dbj|BAG21589.1| putative TetR-family transcriptional regulator [Streptomyces 
griseus subsp. griseus NBRC 13350]
 gi|326659533|gb|EGE44379.1| regulatory protein TetR [Streptomyces griseus XylebKG-1]
Length=205

 Score =  172 bits (437),  Expect = 2e-41, Method: Compositional matrix adjust.
 Identities = 98/192 (52%), Positives = 126/192 (66%), Gaps = 7/192 (3%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+L  A RLFAERGF  V +++IGAA G+SGP +YRHFP K+++L ELLVG+S RLL
Sbjct  14   RREQILREAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFPGKDAMLAELLVGISERLL  73

Query  86   AGAR-----DVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRK  140
             G R     D      +    LD LIE H+DFAL +  LI + DR+L  L     ++VR+
Sbjct  74   EGGRMRVSEDAARGGGSPEELLDALIEGHIDFALDDRPLITLHDRELDRLRDTDRKRVRR  133

Query  141  AQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVL  200
             QR+YVEVWVGV+R L P LAE  AR+  HAVFGLLNSTPH +   ++ P R V A A+L
Sbjct  134  LQREYVEVWVGVVRALYPALAENRARVTVHAVFGLLNSTPH-LARPEALPGRAVTA-ALL  191

Query  201  RAMTVAALSAAD  212
              +   A +AA+
Sbjct  192  HRLARGAFAAAE  203


>gi|163839307|ref|YP_001623712.1| TetR family transcriptional regulator [Renibacterium salmoninarum 
ATCC 33209]
 gi|162952783|gb|ABY22298.1| transcriptional regulator, TetR family [Renibacterium salmoninarum 
ATCC 33209]
Length=219

 Score =  171 bits (434),  Expect = 4e-41, Method: Compositional matrix adjust.
 Identities = 94/201 (47%), Positives = 128/201 (64%), Gaps = 2/201 (0%)

Query  10   PGQPEATNRRSQLKSDRRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNK  69
            P Q     +RS  K+ R+  LL AA  L+A+RGF  V +E++GAAAGVSGPA+YRHF  K
Sbjct  17   PLQETEPTQRSLAKASRKQALLDAAAELYAQRGFNGVSIEELGAAAGVSGPAVYRHFSGK  76

Query  70   ESLLVELLVGVSARLLAGARDVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAH  129
            +++L  LL+GVS  LL G R V   +A+    +  L+ FH++FALG AD+IR+QDRDLA 
Sbjct  77   QAVLAALLMGVSEDLLTGGRAVAMDNADPETTIRKLVAFHVEFALGNADIIRVQDRDLAS  136

Query  130  LPAVAERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAA--D  187
            +       VR  QR+YV++WV VL +L P     + R+ AHA FGL+NSTPHS+++    
Sbjct  137  MNDDDRHAVRTLQREYVQLWVQVLSQLYPRADTLELRVQAHAAFGLINSTPHSLRSYSRS  196

Query  188  SKPARTVRARAVLRAMTVAAL  208
             K A    AR +L  M +A L
Sbjct  197  GKIAPAKVARPILERMALAGL  217


>gi|239987889|ref|ZP_04708553.1| TetR family transcriptional regulator [Streptomyces roseosporus 
NRRL 11379]
Length=205

 Score =  171 bits (434),  Expect = 4e-41, Method: Compositional matrix adjust.
 Identities = 98/192 (52%), Positives = 125/192 (66%), Gaps = 7/192 (3%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+L  A RLFAERGF  V +++IGAA G+SGP +YRHFP K+++L ELLVG+S RLL
Sbjct  14   RREQILREAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFPGKDAMLAELLVGISERLL  73

Query  86   AGAR-----DVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRK  140
             G R     D      +  A LD LIE H+DFAL +  LI + DR+L  L     ++VR+
Sbjct  74   EGGRLRVAEDEARGDGSPEALLDALIEGHIDFALDDRPLITLHDRELDRLRDTDRKRVRR  133

Query  141  AQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVL  200
             QR+YVEVWVGV+R L P L E  AR+  HAVFGLLNSTPH +   D+ P R   A A+L
Sbjct  134  LQREYVEVWVGVVRALYPSLPENRARVTVHAVFGLLNSTPH-LARPDALPGRAATA-ALL  191

Query  201  RAMTVAALSAAD  212
              +   A +AA+
Sbjct  192  HRLARGAFAAAE  203


>gi|290960186|ref|YP_003491368.1| TetR family transcriptional regulator [Streptomyces scabiei 87.22]
 gi|260649712|emb|CBG72827.1| putative TetR-family regulatory protein [Streptomyces scabiei 
87.22]
Length=198

 Score =  171 bits (433),  Expect = 6e-41, Method: Compositional matrix adjust.
 Identities = 94/178 (53%), Positives = 120/178 (68%), Gaps = 3/178 (1%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+L  A RLFAERGF  V +++IGAA G+SGP +YRHF  K+++L ELLVG+S +LL
Sbjct  10   RREQILKEAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFAGKDAMLAELLVGISGQLL  69

Query  86   AGARDVTTRSANLAAA--LDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQR  143
             GA+     +  ++ A  LD LIE H+DFAL +  LI + DR+L  L     + VR+ QR
Sbjct  70   TGAKRRVAEADGVSGAEVLDSLIEGHIDFALDDRPLITLHDRELDRLRDSDRKLVRQLQR  129

Query  144  QYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR  201
            QYVE+WVGVLRE+ PGLAE  AR   H+VFGLLNSTPH +  A S P R   A  + R
Sbjct  130  QYVELWVGVLREVYPGLAEPAARSAVHSVFGLLNSTPH-LGRAGSLPGRAATAELLHR  186


>gi|344999846|ref|YP_004802700.1| TetR family transcriptional regulator [Streptomyces sp. SirexAA-E]
 gi|344315472|gb|AEN10160.1| transcriptional regulator, TetR family [Streptomyces sp. SirexAA-E]
Length=215

 Score =  171 bits (432),  Expect = 9e-41, Method: Compositional matrix adjust.
 Identities = 97/190 (52%), Positives = 124/190 (66%), Gaps = 6/190 (3%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+L  A RLFAERGF  V +++IGAA G+SGP +YRHFP K+++L ELLVG+S RLL
Sbjct  22   RREQILKEAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFPGKDAMLAELLVGISERLL  81

Query  86   AGARDVTTRSA----NLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA  141
             G R V+   A    +  A LD LIE H+DFAL +  LI + DR+L  L     ++VR+ 
Sbjct  82   DGGRRVSEERAAPGGSPEALLDALIEGHIDFALDDRPLITLHDRELDRLRDTDRKRVRRL  141

Query  142  QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR  201
            QRQYVEVWV  +R L P L E +AR+  HAVFGLLNSTPH +   ++ P R   A A+L 
Sbjct  142  QRQYVEVWVEAVRALYPSLPEGEARVTVHAVFGLLNSTPH-LARPEALPGRAATA-ALLH  199

Query  202  AMTVAALSAA  211
             +   A  AA
Sbjct  200  RLARGAFEAA  209


>gi|345015342|ref|YP_004817696.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113]
 gi|344041691|gb|AEM87416.1| regulatory protein TetR [Streptomyces violaceusniger Tu 4113]
Length=208

 Score =  170 bits (430),  Expect = 1e-40, Method: Compositional matrix adjust.
 Identities = 99/190 (53%), Positives = 123/190 (65%), Gaps = 6/190 (3%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+L  A RLFAERGF  V +++IGAA G+SGP +YRHFP KE++L ELLVG+S RLL
Sbjct  10   RREQILKEAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFPGKEAMLAELLVGISGRLL  69

Query  86   AGA--RDVTTRSANLAAA--LDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA  141
             G   R      A LA A  LD LIE H+DFA+ +  LI + DR+L  L     + VR  
Sbjct  70   TGGKRRAAEGEGAGLAPAEVLDSLIEGHIDFAIDDRPLIILHDRELDRLRDTDRKLVRSL  129

Query  142  QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR  201
            QRQYVE+WV V+RE+ P LAEA+AR   HAVFGLLNSTPH +    + P R   A A+L 
Sbjct  130  QRQYVELWVEVVREVYPRLAEAEARACVHAVFGLLNSTPH-LGRPGALPGRAATA-ALLH  187

Query  202  AMTVAALSAA  211
             + + A   A
Sbjct  188  RLALGAFGGA  197


>gi|289771485|ref|ZP_06530863.1| TetR family transcriptional regulator [Streptomyces lividans 
TK24]
 gi|289701684|gb|EFD69113.1| TetR family transcriptional regulator [Streptomyces lividans 
TK24]
Length=208

 Score =  170 bits (430),  Expect = 1e-40, Method: Compositional matrix adjust.
 Identities = 101/197 (52%), Positives = 125/197 (64%), Gaps = 14/197 (7%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+L  A RLFAERGF  V +++IGAA G+SGP +YRHFP K+++L ELLVG+S  LL
Sbjct  10   RREQILKEAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFPGKDAMLAELLVGISDSLL  69

Query  86   AGAR------DVTTRSANLAAA------LDGLIEFHLDFALGEADLIRIQDRDLAHLPAV  133
             GA+      D  T S   A A      LD LIE H+DFAL +  LI + DR+L  L   
Sbjct  70   TGAKRRLAEADGATGSGARAGADGPGAVLDSLIEGHIDFALDDRPLITLHDRELDRLRDA  129

Query  134  AERQVRKAQRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPART  193
              + VR+ QRQYVE+WVGVLRE+ P LAE  AR   H+VFGLLNSTPH +    S P R 
Sbjct  130  DRKMVRQLQRQYVELWVGVLREVYPALAEPAARSAVHSVFGLLNSTPH-LGRPGSLPGRA  188

Query  194  VRARAVLRAMTVAALSA  210
            V A ++L  M   A +A
Sbjct  189  VTA-SLLHRMARGAFAA  204


>gi|302545218|ref|ZP_07297560.1| TetR family transcriptional regulator [Streptomyces hygroscopicus 
ATCC 53653]
 gi|302462836|gb|EFL25929.1| TetR family transcriptional regulator [Streptomyces himastatinicus 
ATCC 53653]
Length=212

 Score =  170 bits (430),  Expect = 2e-40, Method: Compositional matrix adjust.
 Identities = 97/190 (52%), Positives = 123/190 (65%), Gaps = 6/190 (3%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+L  A RLFAERGF  V +++IGAA G+SGP +YRHF  KE++L ELLVG+S RLL
Sbjct  10   RREQILKEAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFAGKEAMLAELLVGISGRLL  69

Query  86   AGARDVTTRSANL----AAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA  141
             G +  T  +       AA LD LIE H+DFAL +  LI + DR+L  L     + VR  
Sbjct  70   TGGKRRTAEATEAGDAPAALLDSLIEGHIDFALDDRPLIILHDRELDRLRDTDRKLVRSL  129

Query  142  QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR  201
            QRQYVE+WV V+R++ PGL EA+AR   HAVFGLLNSTPH +    + P R   A A+L 
Sbjct  130  QRQYVELWVEVVRQVYPGLTEAEARACVHAVFGLLNSTPH-LGRPGALPGREATA-ALLH  187

Query  202  AMTVAALSAA  211
             + + A  AA
Sbjct  188  RLALGAFGAA  197


>gi|302560532|ref|ZP_07312874.1| TetR family transcriptional regulator [Streptomyces griseoflavus 
Tu4000]
 gi|302478150|gb|EFL41243.1| TetR family transcriptional regulator [Streptomyces griseoflavus 
Tu4000]
Length=199

 Score =  169 bits (428),  Expect = 2e-40, Method: Compositional matrix adjust.
 Identities = 92/170 (55%), Positives = 115/170 (68%), Gaps = 4/170 (2%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+L  A RLFAERGF  V +++IGAA G+SGP +YRHFP K+++L ELLVG+S +LL
Sbjct  10   RREQILKEAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFPGKDAMLAELLVGISGQLL  69

Query  86   AGARDVTTRSANLAA---ALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKAQ  142
             GA+     +   AA    LD LIE H+DFAL +  LI + DR+L  L     + VR+ Q
Sbjct  70   TGAKRRLQEADGAAAPEAVLDSLIEGHIDFALDDRPLITLHDRELDRLRDTDRKLVRQLQ  129

Query  143  RQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPAR  192
            RQYVE+WVGV+REL P LAE  AR   H+VFGLLNSTPH  +   S P R
Sbjct  130  RQYVELWVGVVRELYPELAEPAARSAVHSVFGLLNSTPHLTRPG-SLPGR  178


>gi|297160331|gb|ADI10043.1| TetR family transcriptional regulator [Streptomyces bingchenggensis 
BCW-1]
Length=203

 Score =  169 bits (427),  Expect = 3e-40, Method: Compositional matrix adjust.
 Identities = 94/191 (50%), Positives = 123/191 (65%), Gaps = 5/191 (2%)

Query  26   RRFQLLAAAERLFAERGFLAVRLEDIGAAAGVSGPAIYRHFPNKESLLVELLVGVSARLL  85
            RR Q+L  A RLFAERGF  V +++IGAA G+SGP +YRHFP KE++L ELLVG+S RLL
Sbjct  10   RREQILKEAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFPGKEAMLAELLVGISGRLL  69

Query  86   AGAR----DVTTRSANLAAALDGLIEFHLDFALGEADLIRIQDRDLAHLPAVAERQVRKA  141
             G +    + + +  +  A LD L+  H+DFAL +  LI + DR+L  L     + VR  
Sbjct  70   TGGKQRAAEASGQERDPGAVLDSLVRGHIDFALDDRPLIILHDRELDRLRDTDRKLVRSL  129

Query  142  QRQYVEVWVGVLRELNPGLAEADARLMAHAVFGLLNSTPHSMKAADSKPARTVRARAVLR  201
            QRQYVE+WV V+RE++P LAE +AR   HAVFGLLNSTPH +    + P R   A  + R
Sbjct  130  QRQYVELWVQVVREVHPRLAEPEARACVHAVFGLLNSTPH-LSRPGALPGRAATAELLHR  188

Query  202  AMTVAALSAAD  212
                A  +AAD
Sbjct  189  LALGAFRAAAD  199



Lambda     K      H
   0.321    0.133    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 257507162856


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40