BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2528c

Length=306
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609665|ref|NP_217044.1|  restriction system protein mrr [Myc...   613    7e-174
gi|167967329|ref|ZP_02549606.1|  probable restriction system prot...   613    1e-173
gi|31793709|ref|NP_856202.1|  restriction system protein mrr [Myc...   612    2e-173
gi|289746313|ref|ZP_06505691.1|  restriction system protein mrr [...   611    4e-173
gi|121638411|ref|YP_978635.1|  putative restriction system protei...   610    9e-173
gi|340627543|ref|YP_004745995.1|  putative restriction system pro...   596    2e-168
gi|256826065|ref|YP_003150025.1|  restriction endonuclease [Kytoc...   382    5e-104
gi|319950295|ref|ZP_08024215.1|  restriction system protein mrr [...   361    9e-98 
gi|163792392|ref|ZP_02186369.1|  mrr restriction system protein [...   260    2e-67 
gi|332704545|ref|ZP_08424633.1|  restriction endonuclease [Desulf...   256    3e-66 
gi|254470574|ref|ZP_05083978.1|  mrr restriction system protein [...   256    4e-66 
gi|119715822|ref|YP_922787.1|  restriction endonuclease [Nocardio...   253    3e-65 
gi|254514672|ref|ZP_05126733.1|  restriction endonuclease [gamma ...   251    9e-65 
gi|339484107|ref|YP_004695893.1|  restriction endonuclease [Nitro...   251    1e-64 
gi|288959542|ref|YP_003449883.1|  restriction system protein [Azo...   250    2e-64 
gi|333373834|ref|ZP_08465733.1|  mrr restriction system protein [...   245    8e-63 
gi|116749960|ref|YP_846647.1|  restriction endonuclease [Syntroph...   244    1e-62 
gi|159028005|emb|CAO87965.1|  mrr [Microcystis aeruginosa PCC 7806]    243    2e-62 
gi|254786397|ref|YP_003073826.1|  Mrr restriction system protein ...   241    8e-62 
gi|88601780|ref|YP_501958.1|  restriction endonuclease [Methanosp...   241    1e-61 
gi|300310547|ref|YP_003774639.1|  5-methylcytosine-specific restr...   240    2e-61 
gi|166367573|ref|YP_001659846.1|  Mrr restriction system protein ...   239    5e-61 
gi|344200362|ref|YP_004784688.1|  restriction endonuclease [Acidi...   238    1e-60 
gi|17233148|ref|NP_490238.1|  mrr restriction system protein [Nos...   237    1e-60 
gi|34540717|ref|NP_905196.1|  Mrr restriction system protein [Por...   237    2e-60 
gi|75812373|ref|YP_319992.1|  restriction endonuclease [Anabaena ...   237    2e-60 
gi|188994846|ref|YP_001929098.1|  putative Mrr restriction system...   237    2e-60 
gi|297625533|ref|YP_003687296.1|  restriction system protein [Pro...   235    8e-60 
gi|222525259|ref|YP_002569730.1|  restriction endonuclease [Chlor...   234    1e-59 
gi|334146688|ref|YP_004509616.1|  Mrr restriction system protein ...   234    1e-59 
gi|163847411|ref|YP_001635455.1|  restriction endonuclease [Chlor...   234    1e-59 
gi|251771181|gb|EES51763.1|  restriction endonuclease [Leptospiri...   234    2e-59 
gi|153003951|ref|YP_001378276.1|  restriction endonuclease [Anaer...   232    6e-59 
gi|257058969|ref|YP_003136857.1|  restriction endonuclease [Cyano...   231    1e-58 
gi|254466305|ref|ZP_05079716.1|  Mrr restriction system protein [...   230    2e-58 
gi|218245921|ref|YP_002371292.1|  restriction endonuclease [Cyano...   230    2e-58 
gi|270157736|ref|ZP_06186393.1|  Mrr restriction system protein [...   230    3e-58 
gi|302343460|ref|YP_003807989.1|  restriction endonuclease [Desul...   229    3e-58 
gi|295696350|ref|YP_003589588.1|  restriction endonuclease [Bacil...   229    4e-58 
gi|344339026|ref|ZP_08769956.1|  restriction endonuclease [Thioca...   228    7e-58 
gi|320104887|ref|YP_004180478.1|  restriction endonuclease [Isosp...   228    7e-58 
gi|237755764|ref|ZP_04584368.1|  Mrr restriction system protein [...   228    1e-57 
gi|119471839|ref|ZP_01614172.1|  methylated adenine and cytosine ...   228    1e-57 
gi|338536845|ref|YP_004670179.1|  restriction endonuclease [Myxoc...   226    3e-57 
gi|323136815|ref|ZP_08071896.1|  restriction endonuclease [Methyl...   226    3e-57 
gi|336115221|ref|YP_004569988.1|  restriction endonuclease [Bacil...   226    4e-57 
gi|330997041|ref|ZP_08320903.1|  restriction endonuclease [Parapr...   226    4e-57 
gi|148358355|ref|YP_001249562.1|  Mrr restriction system protein ...   225    5e-57 
gi|339442916|ref|YP_004708921.1|  hypothetical protein CXIVA_1852...   225    5e-57 
gi|154245042|ref|YP_001416000.1|  restriction endonuclease [Xanth...   225    7e-57 


>gi|15609665|ref|NP_217044.1| restriction system protein mrr [Mycobacterium tuberculosis H37Rv]
 gi|15842062|ref|NP_337099.1| Mrr restriction system protein [Mycobacterium tuberculosis CDC1551]
 gi|148662365|ref|YP_001283888.1| restriction system protein Mrr [Mycobacterium tuberculosis H37Ra]
 68 more sequence titles
 Length=306

 Score =  613 bits (1582),  Expect = 7e-174, Method: Compositional matrix adjust.
 Identities = 306/306 (100%), Positives = 306/306 (100%), Gaps = 0/306 (0%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH
Sbjct  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP
Sbjct  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
            VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG
Sbjct  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180

Query  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
            YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK
Sbjct  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240

Query  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300
            QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE
Sbjct  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300

Query  301  DFFDGL  306
            DFFDGL
Sbjct  301  DFFDGL  306


>gi|167967329|ref|ZP_02549606.1| probable restriction system protein mrr [Mycobacterium tuberculosis 
H37Ra]
Length=306

 Score =  613 bits (1580),  Expect = 1e-173, Method: Compositional matrix adjust.
 Identities = 305/306 (99%), Positives = 306/306 (100%), Gaps = 0/306 (0%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH
Sbjct  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP
Sbjct  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
            VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG
Sbjct  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180

Query  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
            YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPK+HEFAGALLGK
Sbjct  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKMHEFAGALLGK  240

Query  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300
            QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE
Sbjct  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300

Query  301  DFFDGL  306
            DFFDGL
Sbjct  301  DFFDGL  306


>gi|31793709|ref|NP_856202.1| restriction system protein mrr [Mycobacterium bovis AF2122/97]
 gi|31619303|emb|CAD94741.1| PROBABLE RESTRICTION SYSTEM PROTEIN MRR [Mycobacterium bovis 
AF2122/97]
Length=306

 Score =  612 bits (1579),  Expect = 2e-173, Method: Compositional matrix adjust.
 Identities = 305/306 (99%), Positives = 306/306 (100%), Gaps = 0/306 (0%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH
Sbjct  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP
Sbjct  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
            VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG
Sbjct  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180

Query  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
            YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK
Sbjct  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240

Query  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300
            QGDRGVYITTSSFSRGAR+EAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE
Sbjct  241  QGDRGVYITTSSFSRGARQEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300

Query  301  DFFDGL  306
            DFFDGL
Sbjct  301  DFFDGL  306


>gi|289746313|ref|ZP_06505691.1| restriction system protein mrr [Mycobacterium tuberculosis 02_1987]
 gi|289686841|gb|EFD54329.1| restriction system protein mrr [Mycobacterium tuberculosis 02_1987]
Length=306

 Score =  611 bits (1576),  Expect = 4e-173, Method: Compositional matrix adjust.
 Identities = 305/306 (99%), Positives = 305/306 (99%), Gaps = 0/306 (0%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MTIPDAQTLMRPILAYLADGQAKS KDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH
Sbjct  1    MTIPDAQTLMRPILAYLADGQAKSGKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP
Sbjct  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
            VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG
Sbjct  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180

Query  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
            YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK
Sbjct  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240

Query  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300
            QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE
Sbjct  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300

Query  301  DFFDGL  306
            DFFDGL
Sbjct  301  DFFDGL  306


>gi|121638411|ref|YP_978635.1| putative restriction system protein mrr [Mycobacterium bovis 
BCG str. Pasteur 1173P2]
 gi|224990905|ref|YP_002645592.1| putative restriction system protein [Mycobacterium bovis BCG 
str. Tokyo 172]
 gi|121494059|emb|CAL72537.1| Probable restriction system protein mrr [Mycobacterium bovis 
BCG str. Pasteur 1173P2]
 gi|224774018|dbj|BAH26824.1| putative restriction system protein [Mycobacterium bovis BCG 
str. Tokyo 172]
 gi|341602449|emb|CCC65125.1| probable restriction system protein mrr [Mycobacterium bovis 
BCG str. Moreau RDJ]
Length=306

 Score =  610 bits (1573),  Expect = 9e-173, Method: Compositional matrix adjust.
 Identities = 305/306 (99%), Positives = 305/306 (99%), Gaps = 0/306 (0%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH
Sbjct  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAH ERVDMAVLREFPSYIAFRERTKAKQP
Sbjct  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHLERVDMAVLREFPSYIAFRERTKAKQP  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
            VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG
Sbjct  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180

Query  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
            YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK
Sbjct  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240

Query  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300
            QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE
Sbjct  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300

Query  301  DFFDGL  306
            DFFDGL
Sbjct  301  DFFDGL  306


>gi|340627543|ref|YP_004745995.1| putative restriction system protein MRR [Mycobacterium canettii 
CIPT 140010059]
 gi|340005733|emb|CCC44899.1| putative restriction system protein MRR [Mycobacterium canettii 
CIPT 140010059]
Length=306

 Score =  596 bits (1536),  Expect = 2e-168, Method: Compositional matrix adjust.
 Identities = 297/306 (98%), Positives = 301/306 (99%), Gaps = 0/306 (0%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH
Sbjct  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            WSLTHMSQAGLLDRP RG VQ+T TGRQVLKAHPERVD+AVLREFPSYIAFRERTKAKQP
Sbjct  61   WSLTHMSQAGLLDRPARGQVQITGTGRQVLKAHPERVDIAVLREFPSYIAFRERTKAKQP  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
            VDA AKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVI LLEAMG
Sbjct  121  VDAAAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIGLLEAMG  180

Query  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
            YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK
Sbjct  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240

Query  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300
            QGDRGVYITTSSFSRGARE+AERINARIELIDGARLAELLVRYRVGVQAVQTVEL+RLDE
Sbjct  241  QGDRGVYITTSSFSRGAREQAERINARIELIDGARLAELLVRYRVGVQAVQTVELVRLDE  300

Query  301  DFFDGL  306
            DFFDGL
Sbjct  301  DFFDGL  306


>gi|256826065|ref|YP_003150025.1| restriction endonuclease [Kytococcus sedentarius DSM 20547]
 gi|256689458|gb|ACV07260.1| restriction endonuclease [Kytococcus sedentarius DSM 20547]
Length=306

 Score =  382 bits (980),  Expect = 5e-104, Method: Compositional matrix adjust.
 Identities = 198/306 (65%), Positives = 242/306 (80%), Gaps = 3/306 (0%)

Query  3    IPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVHWS  62
            IPD QTLMRP+LA L DGQ  + +D+ A ++  F LS+ E A+ LPSGR     +RV W+
Sbjct  2    IPDFQTLMRPVLAELEDGQVHAVRDLRARLAITFQLSEAELAEKLPSGRSPVFTNRVGWA  61

Query  63   LTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAK--QP  120
             TH+SQAGLL R  RG  ++T  GRQVL+ HP+RVD+ VL EF +Y AFRERT+ +  QP
Sbjct  62   TTHLSQAGLLAREGRGLYRLTQAGRQVLERHPDRVDVRVLDEFQAYRAFRERTREQEPQP  121

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
              AT  R +    + +PE+L+  A++ NRAAVEG++L+ AL LSPTGFEDLVI+LL  MG
Sbjct  122  TLATTSRQTPPTSE-TPEELLANAISINRAAVEGDVLQAALGLSPTGFEDLVIQLLSRMG  180

Query  181  YGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
            YGRAG+VERTSA+GDAG+DGIISQDPLGLDRIYVQAKRYA ++T+ RP+IHEFAGALLGK
Sbjct  181  YGRAGSVERTSATGDAGVDGIISQDPLGLDRIYVQAKRYAEERTVDRPRIHEFAGALLGK  240

Query  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300
            QGDRGV+ITTS+FS GA +EAERINARIELIDG RLA+LLV+Y VGVQ  QT  L RLDE
Sbjct  241  QGDRGVFITTSTFSGGAIQEAERINARIELIDGKRLAQLLVQYGVGVQEQQTAVLYRLDE  300

Query  301  DFFDGL  306
            D+F+GL
Sbjct  301  DYFEGL  306


>gi|319950295|ref|ZP_08024215.1| restriction system protein mrr [Dietzia cinnamea P4]
 gi|319436051|gb|EFV91251.1| restriction system protein mrr [Dietzia cinnamea P4]
Length=275

 Score =  361 bits (926),  Expect = 9e-98, Method: Compositional matrix adjust.
 Identities = 183/277 (67%), Positives = 219/277 (80%), Gaps = 2/277 (0%)

Query  30   AAMSDEFGLSDDERAQMLPSGRQRTMYDRVHWSLTHMSQAGLLDRPTRGHVQVTDTGRQV  89
            A+++D+FGL   ER+Q++PSG+ RT  +RV WSLTH+SQAG+++RP+RG V +TD GR +
Sbjct  1    ASIADQFGLDAQERSQLIPSGKARTFDNRVGWSLTHLSQAGVVERPSRGVVSITDEGRAI  60

Query  90   LKAHPERVDMAVLREFPSYIAFRERTKAKQPVDATAKRPSGDDVQVSPEDLIDAALAENR  149
            L  HP R+ +  L E+PSY  FR R K     DA +   S +  +++P +L   A+  NR
Sbjct  61   LARHPGRIGVRELNEYPSYREFRSRKKRAVEDDAQSDESSSE--ELTPSELAAQAVEINR  118

Query  150  AAVEGEILKKALTLSPTGFEDLVIRLLEAMGYGRAGAVERTSASGDAGIDGIISQDPLGL  209
            AAVEGE+LK A  LSP GFE+LVIRLLE MGYGRAG+VERTS SGDAG+DGIISQDPLGL
Sbjct  119  AAVEGEVLKSAHELSPAGFENLVIRLLEKMGYGRAGSVERTSFSGDAGVDGIISQDPLGL  178

Query  210  DRIYVQAKRYAVDQTIGRPKIHEFAGALLGKQGDRGVYITTSSFSRGAREEAERINARIE  269
            DRIYVQAKRYA ++TI RP+IHEFAGALLGKQGDRGV+ITTS+FS GA  EAERINARIE
Sbjct  179  DRIYVQAKRYAEERTIHRPRIHEFAGALLGKQGDRGVFITTSTFSAGAIAEAERINARIE  238

Query  270  LIDGARLAELLVRYRVGVQAVQTVELLRLDEDFFDGL  306
            LIDG RLAELLV Y VGVQA QTV L RLDEDFF+ L
Sbjct  239  LIDGPRLAELLVAYGVGVQAEQTVTLYRLDEDFFESL  275


>gi|163792392|ref|ZP_02186369.1| mrr restriction system protein [alpha proteobacterium BAL199]
 gi|159182097|gb|EDP66606.1| mrr restriction system protein [alpha proteobacterium BAL199]
Length=311

 Score =  260 bits (664),  Expect = 2e-67, Method: Compositional matrix adjust.
 Identities = 133/311 (43%), Positives = 202/311 (65%), Gaps = 12/311 (3%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD QTLM P+L   A G+ +   D    ++D+ GLS  ER ++LPSGRQR +++R+H
Sbjct  1    MAIPDYQTLMLPVLRLAAAGETR-VPDAAETIADDLGLSAAEREELLPSGRQRLLHNRIH  59

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+  +M++AGL+D+P RG   V++TG+Q+L   PER+D+A L ++  +  F       + 
Sbjct  60   WAKFYMNKAGLIDQPRRGRFVVSETGKQLLSTSPERIDVARLMQYQEFREFYTNAGTAKE  119

Query  121  VDA------TAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIR  174
            VD        A  PS      +PE+ I+AA    + A+ GE+L++ L  SP+ FE +++ 
Sbjct  120  VDGPPDQHQVAPSPSAGQ---TPEEQIEAAHRALQTALRGELLQRILQNSPSFFEQVIVD  176

Query  175  LLEAMGYGRA--GAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHE  232
            LL AMGYG +   A E+   +GD G+DG+I++D LGLDR+Y+QAKRY  + ++GRP++  
Sbjct  177  LLVAMGYGGSHRNAAEQLGRTGDGGVDGVINEDRLGLDRVYIQAKRYGPNVSVGRPEVQA  236

Query  233  FAGALLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQT  292
            F G+L+G    + V++TTS+FS+ A + A  ++ RI LIDG RL +L++ Y VGV+  +T
Sbjct  237  FVGSLVGLGASKSVFVTTSTFSQHATDFARHLSQRIILIDGVRLGDLMIEYNVGVRVART  296

Query  293  VELLRLDEDFF  303
            VE  RLDEDFF
Sbjct  297  VEFKRLDEDFF  307


>gi|332704545|ref|ZP_08424633.1| restriction endonuclease [Desulfovibrio africanus str. Walvis 
Bay]
 gi|332554694|gb|EGJ51738.1| restriction endonuclease [Desulfovibrio africanus str. Walvis 
Bay]
Length=299

 Score =  256 bits (655),  Expect = 3e-66, Method: Compositional matrix adjust.
 Identities = 129/308 (42%), Positives = 203/308 (66%), Gaps = 15/308 (4%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD QT+M P+L   +DG+ +S+ +    ++D F L+  ER ++LPSG+Q+   +RV 
Sbjct  1    MPIPDFQTIMLPLLELSSDGKVRSSAEYRDTLADRFTLTPAEREELLPSGKQQIFSNRVS  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+  ++ +AGLL +P RGH Q+T+ GR+ L+  P+R+++  L+++P + AFRE++  K+P
Sbjct  61   WASFYLQRAGLLTKPRRGHYQITERGREALRTRPQRINIEFLQQYPEFNAFREKSTDKKP  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
            V+ T    +G+    +PE+ ++ A  + R  +  EIL++  + +P  FE LV+ LL  MG
Sbjct  121  VEETR---TGE----TPEETLETAFQQMRGGLALEILEQVKSCTPQFFERLVVELLVGMG  173

Query  181  YG----RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGA  236
            YG     AG       SGD GIDGII +D LGLD IY+QAKR+  + T+GRP++ +F GA
Sbjct  174  YGGTMHDAGMA--VGKSGDEGIDGIIKEDRLGLDLIYLQAKRW--EGTVGRPEVQKFVGA  229

Query  237  LLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELL  296
            L GK   +GV+ITT +F++GA E A  I++++ LIDG RLAEL++ + VGV    T ++ 
Sbjct  230  LHGKHARKGVFITTGTFAQGAVEYAASIDSKVVLIDGKRLAELMIEFDVGVSTKATYQVK  289

Query  297  RLDEDFFD  304
            R+D D+F+
Sbjct  290  RIDSDYFN  297


>gi|254470574|ref|ZP_05083978.1| mrr restriction system protein [Pseudovibrio sp. JE062]
 gi|211960885|gb|EEA96081.1| mrr restriction system protein [Pseudovibrio sp. JE062]
Length=307

 Score =  256 bits (653),  Expect = 4e-66, Method: Compositional matrix adjust.
 Identities = 133/305 (44%), Positives = 199/305 (66%), Gaps = 4/305 (1%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MTIPD QTLM P+L  LA  +A    D++  ++ EF LSDD+  ++LPSG+ + + +R+H
Sbjct  1    MTIPDYQTLMLPVLR-LAANEAVRVVDLVKPIATEFLLSDDDLEELLPSGKGKRLNNRIH  59

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++S+AGLL+ P+RG+   TD G +VL + PER+D A L  +  +  FR   K    
Sbjct  60   WAKTYLSKAGLLENPSRGYFLATDEGHKVLVSSPERIDNAFLTRYEKFQEFRAGGKETDE  119

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
               T    SG D + +PE+ ID A    RA++  ++L++    SP+ FE L+I L+ +MG
Sbjct  120  SIGTL-HLSGTDDKATPEEQIDNAYETLRASLGTDLLERISQNSPSFFEGLIIDLMMSMG  178

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG   A A  +   SGD G+DG+I +D LGLDR+Y+QAKRY  +  +GRP++  F G+L+
Sbjct  179  YGGSHASAARQLGRSGDGGVDGVIDEDRLGLDRVYLQAKRYKAENVVGRPEVQGFVGSLV  238

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            G    +G+++TTSSFS+ AR+ AE +  RI LIDGA L +L+V + VGV+  +T+ + R+
Sbjct  239  GLGATKGIFVTTSSFSKQARDYAEGLVQRIILIDGALLTKLMVEHGVGVRTSRTISIQRI  298

Query  299  DEDFF  303
            DEDFF
Sbjct  299  DEDFF  303


>gi|119715822|ref|YP_922787.1| restriction endonuclease [Nocardioides sp. JS614]
 gi|119536483|gb|ABL81100.1| restriction endonuclease [Nocardioides sp. JS614]
Length=304

 Score =  253 bits (646),  Expect = 3e-65, Method: Compositional matrix adjust.
 Identities = 132/307 (43%), Positives = 200/307 (66%), Gaps = 4/307 (1%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD Q+LMRP+L  LADG+ ++ +D+   +SD   LSDD+R Q + SG    + +RVH
Sbjct  1    MAIPDYQSLMRPVLETLADGRVRAMRDLTEELSDRLSLSDDDRRQTITSG-MSLVANRVH  59

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            WS+T++ +A  +DRP RG VQ+T+ G Q L A P  +  + L +F  Y  F ++ ++K+ 
Sbjct  60   WSVTYLFKARAVDRPQRGRVQITERG-QALLATPGEIRNSTLEQFAEYREFYDKYRSKKA  118

Query  121  V-DATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAM  179
               ++A++PS      SP+DLI  A A+ R  +  E+L+K  ++  T FE LV++LLEAM
Sbjct  119  ARSSSAEQPSSAAEDESPDDLIARAEADARVVLASELLEKVRSIEATAFERLVLKLLEAM  178

Query  180  GYGRAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLG  239
            GYG  G +  T  +GD G+DG+I +D LGL+RIYVQAKRY    T+G  ++  F GA+ G
Sbjct  179  GYGGLGLMRHTGRTGDGGVDGVIEEDKLGLNRIYVQAKRYGAGNTVGSEEMRNFLGAMSG  238

Query  240  KQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLD  299
            K  DRGV++TTS+F+  A  E +    R+ LI+G  L +L++ + VGV+A++   + R++
Sbjct  239  KV-DRGVFLTTSTFTPAATRELDGRGVRVVLINGEELVDLMIDHGVGVEAIKVATINRIN  297

Query  300  EDFFDGL  306
            EDFF+GL
Sbjct  298  EDFFEGL  304


>gi|254514672|ref|ZP_05126733.1| restriction endonuclease [gamma proteobacterium NOR5-3]
 gi|219676915|gb|EED33280.1| restriction endonuclease [gamma proteobacterium NOR5-3]
Length=301

 Score =  251 bits (642),  Expect = 9e-65, Method: Compositional matrix adjust.
 Identities = 130/306 (43%), Positives = 195/306 (64%), Gaps = 8/306 (2%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD QTLM PIL   +DG+  +A + +  ++ +F LS  +  ++LPSG+Q    +R+ 
Sbjct  1    MAIPDYQTLMLPILEMASDGETHTAPEAVDFLAAKFNLSTADVEELLPSGKQARFRNRIG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T+M QAGLL+ P+RG  ++TD G  +L   PERVD +VL  F +++ F+ R   K  
Sbjct  61   WARTYMKQAGLLEYPSRGKFRITDAGLSLLAQQPERVDNSVLESFDAFLEFKGRKSEKGA  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
                     G+    +PE+ +++A  + RA +E E+L  A  +SP  FE LV+ LL AMG
Sbjct  121  EMVVVDTTEGE----TPEEALESAYTKLRADLEAEVLAHAKAVSPGYFEQLVVDLLVAMG  176

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG  RA A      S D GIDG+I++D LGLD IY+QAKR+  + ++ RP++ +F GAL 
Sbjct  177  YGGNRADAARAVGQSNDEGIDGVINEDALGLDVIYLQAKRW--EGSVARPELQKFIGALA  234

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            GKQ  +GV+ITTS F++GA E  ++++ R+ LIDG +LA L+V + VGV  V + E+ R+
Sbjct  235  GKQARKGVFITTSEFTKGAAEFIDKVDPRVILIDGKKLARLMVDHNVGVATVNSFEVKRI  294

Query  299  DEDFFD  304
            D D+F+
Sbjct  295  DSDYFE  300


>gi|339484107|ref|YP_004695893.1| restriction endonuclease [Nitrosomonas sp. Is79A3]
 gi|338806252|gb|AEJ02494.1| restriction endonuclease [Nitrosomonas sp. Is79A3]
Length=303

 Score =  251 bits (641),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 132/307 (43%), Positives = 196/307 (64%), Gaps = 7/307 (2%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MTIPD Q LM P+L   +DG+      ++  ++D+F L+ +ER ++LPSG Q    +RV 
Sbjct  1    MTIPDYQALMLPVLKTASDGKEYKFSQLVEELADQFNLTTEERNELLPSGSQAIFTNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ +++ QA LL  P RG +++T  G ++L   P ++D++VL  +P +I FR R K K  
Sbjct  61   WARSYLKQADLLATPKRGFLRITQKGIELLSKDPIKIDISVLERYPEFIEFRNRKKDK--  118

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
             + +    SG +  ++PED + +A  + R+A+E EIL      SP+ FE LV+ LL  MG
Sbjct  119  -NESLIEASGLESNLTPEDSLASAYNKLRSALEAEILSAIKDASPSFFERLVVDLLVKMG  177

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG  R  A +    SGD GIDGII++D LGLD IY+QAKR+  +  +GRP+I +FAGAL 
Sbjct  178  YGGSRQDAGKALGKSGDGGIDGIINEDRLGLDVIYIQAKRW--EGVVGRPEIQKFAGALQ  235

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            G++  +GV+ITTSSFS+ A+E A  I+ +I LIDG +L+ L+  + VGV  V   E+ +L
Sbjct  236  GQRARKGVFITTSSFSKEAKEYASFIDTKIILIDGEQLSRLMAEHNVGVSIVGQYEVKKL  295

Query  299  DEDFFDG  305
            D D+FD 
Sbjct  296  DSDYFDN  302


>gi|288959542|ref|YP_003449883.1| restriction system protein [Azospirillum sp. B510]
 gi|288911850|dbj|BAI73339.1| restriction system protein [Azospirillum sp. B510]
Length=308

 Score =  250 bits (639),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 131/310 (43%), Positives = 198/310 (64%), Gaps = 8/310 (2%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD QTLM P+L   A G      DV+  ++D F L+D+ERAQ+LPSGRQ T  +RVH
Sbjct  1    MAIPDFQTLMLPVLKTAAGGGEVRIGDVVDQLADVFALTDEERAQLLPSGRQTTFANRVH  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRE-RTKAKQ  119
            W+ +++++AGL+D   R H ++T TGR VL + PER+ +  L +FPS+  FR+   +  +
Sbjct  61   WAKSYLTKAGLVDLTRRAHFRITPTGRDVLNSPPERITIRFLEQFPSFKGFRDGEAETAE  120

Query  120  PVDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAM  179
              D+        +  ++P++++  A     A++  EIL++  + +P  FE  V+ LL  M
Sbjct  121  AADSVEVVLPVAESPLTPDEVMRQAHLRIEASLAEEILQRVRSGTPAFFEKTVVHLLITM  180

Query  180  GYGRAGAVER-----TSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFA  234
            GYG  G+V          SGD G+DG+I QDPLGLDR+YVQAKRYA   T+G   I +F 
Sbjct  181  GYG--GSVTELDKALVGKSGDDGVDGVIDQDPLGLDRVYVQAKRYADGNTVGAGAIRDFF  238

Query  235  GALLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVE  294
            G+L   +  +G+++TTS+F+  ARE A+R+  RI LIDG +LA+L++R+ VG +  +T+ 
Sbjct  239  GSLNLFKATKGLFVTTSAFTTSARETADRLGTRIVLIDGIQLAKLMIRHEVGCRIEETLH  298

Query  295  LLRLDEDFFD  304
            + R+DEDFF+
Sbjct  299  IKRVDEDFFE  308


>gi|333373834|ref|ZP_08465733.1| mrr restriction system protein [Desmospora sp. 8437]
 gi|332969101|gb|EGK08139.1| mrr restriction system protein [Desmospora sp. 8437]
Length=304

 Score =  245 bits (625),  Expect = 8e-63, Method: Compositional matrix adjust.
 Identities = 124/305 (41%), Positives = 195/305 (64%), Gaps = 6/305 (1%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M++PD Q+LM P L  LADGQ  S  ++   ++ EF L+++ER ++LPSGRQRT  +RV 
Sbjct  1    MSVPDYQSLMLPFLKILADGQVHSLGEIKDRLAKEFKLTEEERKELLPSGRQRTFDNRVS  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T+M +A LL+   R   ++T  GR+VL   P  +D+  L +FP ++ F     +K+ 
Sbjct  61   WARTYMKKALLLENTGRAKYRITSRGREVLTMEPVMIDVQFLTQFPEFVEF--INPSKKE  118

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
              ++ ++     +  +PE+ ++    E R  ++ +IL++ +  SP  FE LV+ LL AMG
Sbjct  119  SSSSVRQGESKKIDETPEETLEIGYQELRKNLKQDILEQVMMCSPAFFEKLVVDLLVAMG  178

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG  R+ A +    SGD GIDGII +D LGLD IY+QAKR+  + ++GRP+I +FAG+L+
Sbjct  179  YGGSRSDAGQAIGRSGDEGIDGIIKEDKLGLDTIYIQAKRW--NGSVGRPEIQKFAGSLI  236

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            G+   +GV+ITTS+F+ GA +  +RI+ +I LIDG RLA+ +V + +GV       + R+
Sbjct  237  GQGAHKGVFITTSTFTDGALDYVDRIDRKIVLIDGERLADYMVEFDIGVNEYARYVVKRI  296

Query  299  DEDFF  303
            D D+F
Sbjct  297  DSDYF  301


>gi|116749960|ref|YP_846647.1| restriction endonuclease [Syntrophobacter fumaroxidans MPOB]
 gi|116699024|gb|ABK18212.1| restriction endonuclease [Syntrophobacter fumaroxidans MPOB]
Length=302

 Score =  244 bits (623),  Expect = 1e-62, Method: Compositional matrix adjust.
 Identities = 131/307 (43%), Positives = 194/307 (64%), Gaps = 12/307 (3%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD +++M P+L +  DG+  SAK+   A++ EF LS+ E  Q+LPSGRQ T  +R+ 
Sbjct  1    MAIPDYESIMLPLLRFAGDGKEHSAKEAAQALAVEFALSESELKQLLPSGRQTTFGNRIG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGLL    RG  Q+T  G Q+L   P +++ A L  FP ++ F E  K K  
Sbjct  61   WAGTYLKKAGLLQSSRRGIFQITARGLQLLAEKPIQLNSASLHRFPGFVEFIEARKGKAA  120

Query  121  VDATAKRPSGDD--VQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEA  178
            +      PS DD   + +PE++I+AA    R  +  E+L+     S T FE LV+ L+  
Sbjct  121  I------PSDDDPINRETPEEVIEAAYQRIRQDLASELLQTIKNCSATFFERLVVDLIVK  174

Query  179  MGYG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGA  236
            MGYG  R  A E    SGD GIDGII +D LGLD +Y+QAKR+  D  +GRP++ +FAGA
Sbjct  175  MGYGGTRKDAGEAIGKSGDEGIDGIIKEDRLGLDIVYIQAKRW--DSQVGRPEVQKFAGA  232

Query  237  LLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELL  296
            L G++  +G+++TTS+F++ AR+   RI ++I LIDG  LA+L++ + +GV AV + EL 
Sbjct  233  LQGQRAKKGIFLTTSAFTKEARDYVSRIESKIVLIDGDLLAQLMIDFNIGVAAVASYELK  292

Query  297  RLDEDFF  303
            R+D D+F
Sbjct  293  RIDSDYF  299


>gi|159028005|emb|CAO87965.1| mrr [Microcystis aeruginosa PCC 7806]
Length=307

 Score =  243 bits (621),  Expect = 2e-62, Method: Compositional matrix adjust.
 Identities = 121/305 (40%), Positives = 189/305 (62%), Gaps = 3/305 (0%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD Q++M P+L  LADG+    +++  A+  EF +++ ER +MLPSG+Q+   +RV 
Sbjct  1    MPIPDFQSIMLPLLKILADGKVYKYREIFEALVREFQVTEAERKEMLPSGQQKIFANRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGL++ P R    +++ G+++L  +P R+D   LR+FP +  F    K  + 
Sbjct  61   WAKTYLKKAGLIESPQRATFVISEKGKEILSQNPARIDTKFLRQFPEFQEFTRVNKQNET  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
            +   +   + D  Q +PE+L++ +  E R A+  ++L     LSP  FE LV+ LL  MG
Sbjct  121  ITLESNLSTSDQEQ-NPEELLENSYQEIRQALATDLLFILRKLSPDAFEKLVVELLVKMG  179

Query  181  YGRA--GAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG +   A +    SGD GIDGII +D LGLD IY+QAKR+A +  +GRP+I +F GAL 
Sbjct  180  YGGSIRDAGKAVGKSGDQGIDGIIKEDRLGLDIIYIQAKRWADNNAVGRPEIQKFVGALA  239

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            G+   +G++ITTS F++ A E A R   +I LIDG  L +L++ Y +GV   +  E+ R+
Sbjct  240  GQGAKKGIFITTSYFTQDALEYAPRNEIKIVLIDGEELGQLMIDYNLGVSTQKIYEIKRI  299

Query  299  DEDFF  303
            D D+F
Sbjct  300  DHDYF  304


>gi|254786397|ref|YP_003073826.1| Mrr restriction system protein [Teredinibacter turnerae T7901]
 gi|237684239|gb|ACR11503.1| Mrr restriction system protein [Teredinibacter turnerae T7901]
Length=303

 Score =  241 bits (616),  Expect = 8e-62, Method: Compositional matrix adjust.
 Identities = 125/303 (42%), Positives = 187/303 (62%), Gaps = 6/303 (1%)

Query  3    IPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVHWS  62
            IPD Q+ MRP+LA ++DGQ     +    +   F L++DE+A+ LPSG+Q  + +R+ W+
Sbjct  2    IPDFQSCMRPLLASVSDGQIHRFNESFEQVCMHFQLTEDEQAEKLPSGKQTIIRNRIAWA  61

Query  63   LTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQPVD  122
             T++++AGLL  P R  +Q+TD G+  L+  PER+D+  L++FP ++ F     AK   +
Sbjct  62   RTYLNKAGLLTAPGRSQLQITDRGQAALQQEPERIDVRFLKQFPEFVEFH---TAKPKAN  118

Query  123  ATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMGYG  182
             T      D     P + ++ A +E R  +  E+L+     SP   E LV+ L++AMGYG
Sbjct  119  KTVVVDDNDTEDTDPTERLEEAYSEIRQELIDEVLRAVKQQSPQFLEKLVVELMQAMGYG  178

Query  183  --RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
                 + + T  + D GIDG+I++DPLGLD IY+QAKRY  D TIGR  I  F+GAL  +
Sbjct  179  GWSKESGQATQYTADGGIDGLINEDPLGLDTIYLQAKRYE-DSTIGREAIQAFSGALDMQ  237

Query  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300
            +  +GV+ITTS FS+GA E    I  +I LIDGA+LA L++++ +GV   +T E+  LD 
Sbjct  238  RAHKGVFITTSKFSKGALEYVSMIQKKIILIDGAKLATLMIKHNLGVSVKETYEIKALDT  297

Query  301  DFF  303
            DFF
Sbjct  298  DFF  300


>gi|88601780|ref|YP_501958.1| restriction endonuclease [Methanospirillum hungatei JF-1]
 gi|88187242|gb|ABD40239.1| restriction endonuclease [Methanospirillum hungatei JF-1]
Length=303

 Score =  241 bits (615),  Expect = 1e-61, Method: Compositional matrix adjust.
 Identities = 123/308 (40%), Positives = 197/308 (64%), Gaps = 10/308 (3%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD QT + P+L  + DG+  S +++ + ++  F LS++E  Q LPSG Q T ++RV 
Sbjct  1    MAIPDYQTFLLPVLLAVKDGKEHSVQEIYSQIASSFHLSEEELNQKLPSGVQSTYHNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRE-RTKAKQ  119
            W+ T++ +AGL++ P+RG V++T+ G  VL  +P+R+D   L++FP ++ F++ RT    
Sbjct  61   WAKTYLKKAGLVNTPSRGKVKITERGLAVLSQNPQRIDQNFLKQFPEFLDFKDFRTDNHS  120

Query  120  PVDATAKRPSGD-DVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEA  178
            P+    K  SG  +  ++P+++++ +  + R  +  E+L + +  SP  FE LV+ LL +
Sbjct  121  PL----KEESGTAESTLTPQEILENSYQDVRNKLAHELLSQVMNSSPEFFERLVVDLLVS  176

Query  179  MGYG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGA  236
            MGYG  R+ A ER   +GD GIDGII +D LGLD + +QAKR+    T+GRP+I  F G+
Sbjct  177  MGYGGSRSEAGERVGKTGDDGIDGIIKEDKLGLDTVCIQAKRW--QNTVGRPEIQAFVGS  234

Query  237  LLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELL  296
            L G +  +GV+ITTS FSR A+E  +RI  ++ LIDG  LAEL++ + VGV       + 
Sbjct  235  LAGNRARKGVFITTSRFSREAQEYVQRIEQKVVLIDGETLAELMIDHNVGVSDESRYIVK  294

Query  297  RLDEDFFD  304
            ++D D+F+
Sbjct  295  KIDMDYFE  302


>gi|300310547|ref|YP_003774639.1| 5-methylcytosine-specific restriction endonuclease [Herbaspirillum 
seropedicae SmR1]
 gi|300073332|gb|ADJ62731.1| 5-methylcytosine-specific restriction endonuclease protein [Herbaspirillum 
seropedicae SmR1]
Length=306

 Score =  240 bits (613),  Expect = 2e-61, Method: Compositional matrix adjust.
 Identities = 130/307 (43%), Positives = 192/307 (63%), Gaps = 4/307 (1%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MTIPD Q++M P+L    D +    +D++  ++DEF L+D +RA+MLPSG      +R  
Sbjct  1    MTIPDYQSIMLPLLRLTGDTKEHRFRDLVEQLADEFSLTDAQRAEMLPSGTAPLFDNRAG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ QAGLL    RG +Q+T+ G  +L   P ++D+  LR +  +  F+ R + K+ 
Sbjct  61   WARTYLKQAGLLQSAKRGVLQITERGSDLLSKPPVKIDVEFLRRYQEFREFQVRRRTKEV  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
                A   +      +PED + AA    R+ +E E+L +  ++SP  FE LVI LL +MG
Sbjct  121  DTPDAPNATVASTDQTPEDALAAAYQTLRSNLEAELLDQVRSMSPAFFERLVIDLLVSMG  180

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG  R  A      SGD GIDGII +D LGLD IYVQAKR+  + T+GRP+I +FAGAL 
Sbjct  181  YGGSRQDAASAVGKSGDGGIDGIIKEDRLGLDVIYVQAKRW--EGTVGRPEIQKFAGALQ  238

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            G++ ++GV+ITTSSFS  A E    I+++I L+DG +LA+L+V + VGV  V   E+ ++
Sbjct  239  GQRANKGVFITTSSFSSEAEEYTNIISSKIILLDGRQLAKLMVDHNVGVAQVGLYEIKKI  298

Query  299  DEDFFDG  305
            D D+F+G
Sbjct  299  DSDYFEG  305


>gi|166367573|ref|YP_001659846.1| Mrr restriction system protein [Microcystis aeruginosa NIES-843]
 gi|166089946|dbj|BAG04654.1| Mrr restriction system protein [Microcystis aeruginosa NIES-843]
Length=307

 Score =  239 bits (609),  Expect = 5e-61, Method: Compositional matrix adjust.
 Identities = 120/305 (40%), Positives = 187/305 (62%), Gaps = 3/305 (0%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD Q++M P+L  LADG+    +++  A+  EF +++ ER +MLPSG+Q    +RV 
Sbjct  1    MPIPDFQSIMLPLLKILADGKVYKYREIFEALVREFQVTEAERKEMLPSGQQEIFANRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGL+D P R    +++ G+++L  + + +D   LR+FP +  F    K  + 
Sbjct  61   WAKTYLKKAGLIDSPQRATFVISEKGKEILSQNLDHIDTKFLRQFPEFQEFTRVNKQNET  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
            +   +   + D  Q +PE+L++ +  E R A+  ++L     LSP  FE LV+ LL  MG
Sbjct  121  ITLESNLLASDQEQ-NPEELLENSYQEIRQALATDLLSILRKLSPDAFEKLVVELLVKMG  179

Query  181  YGRA--GAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG +   A +    SGD GIDGII +D LGLD IY+QAKR+A +  +GRP+I +F GAL 
Sbjct  180  YGGSIRDAGKAVGKSGDQGIDGIIKEDRLGLDIIYIQAKRWADNNAVGRPEIQKFVGALA  239

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            G+   +G++ITTS F++ A E A R   +I LIDG  L +L++ Y +GV   +  E+ R+
Sbjct  240  GQGAKKGIFITTSYFTQEALEYAPRNEIKIVLIDGEELGQLMIDYNLGVSTKEIYEIKRI  299

Query  299  DEDFF  303
            D D+F
Sbjct  300  DHDYF  304


>gi|344200362|ref|YP_004784688.1| restriction endonuclease [Acidithiobacillus ferrivorans SS3]
 gi|343775806|gb|AEM48362.1| restriction endonuclease [Acidithiobacillus ferrivorans SS3]
Length=306

 Score =  238 bits (606),  Expect = 1e-60, Method: Compositional matrix adjust.
 Identities = 126/306 (42%), Positives = 187/306 (62%), Gaps = 7/306 (2%)

Query  3    IPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVHWS  62
            IPD Q  M PIL YL+DG     KD+   ++  + +S + R   LPSG QR    RV W+
Sbjct  4    IPDYQFFMLPILEYLSDGHDHGMKDIRDHLAARYAISTELREAFLPSGTQRIFDSRVAWA  63

Query  63   LTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQPVD  122
             T+++QAGL++ P RG V +T  G+++L  HP+ +D+ VL +FP +IAFR + +      
Sbjct  64   KTYITQAGLVESPKRGVVHITARGKELLLQHPQHIDLTVLEQFPEFIAFRNKARKNDETI  123

Query  123  ATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMGYG  182
              A+  S      +PE+ ++ A    R  +  E++ +     PT FE LV+ LL  MGYG
Sbjct  124  VPAELSSVS--TATPEEQLETAFQTIRIDLVSELMDRLKACDPTFFERLVVELLLKMGYG  181

Query  183  R--AGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
            +  A A +    SGD GIDG+IS+D LGLD +Y+QAKR+A   ++GRP+IH+F GAL GK
Sbjct  182  KNLAEAGKAIGRSGDEGIDGVISEDKLGLDSVYLQAKRWA--GSVGRPEIHKFVGALHGK  239

Query  241  QGDRGVYITTSSFSRGAREEAER-INARIELIDGARLAELLVRYRVGVQAVQTVELLRLD  299
               +GV++TT +F+  A+E A R ++ R+ LIDG  LA+ ++ Y +GV      E+ R+D
Sbjct  240  GARKGVFLTTGTFTAEAKEYAARLLDLRVVLIDGPALADYMIDYGLGVTTRTVYEIKRID  299

Query  300  EDFFDG  305
             D+FDG
Sbjct  300  SDWFDG  305


>gi|17233148|ref|NP_490238.1| mrr restriction system protein [Nostoc sp. PCC 7120]
 gi|17135670|dbj|BAB78216.1| mrr restriction system protein [Nostoc sp. PCC 7120]
Length=305

 Score =  237 bits (605),  Expect = 1e-60, Method: Compositional matrix adjust.
 Identities = 120/307 (40%), Positives = 193/307 (63%), Gaps = 9/307 (2%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD Q +M P+L +  D +  S ++ I A++D F L++DER ++LPSGRQ T  +RV 
Sbjct  1    MPIPDYQAIMLPLLKFTTDQKEHSLQETIDALADHFQLTEDERKELLPSGRQPTFNNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGL++   RG+ ++TD G   +K +P  ++  +LR+FP ++ F+  T   Q 
Sbjct  61   WARTYLKKAGLVESTKRGYFRITDRGIDTIKTNPVEINAKILRQFPEFLEFQNYT---QQ  117

Query  121  VDATAKRPSGDDVQV--SPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEA  178
             + +    SG ++    +PE+ ++ A+ +    +  ++L+     SP  FE LV+ LL  
Sbjct  118  SEESTSNGSGTEINTTRTPEEDVELAIQKLTKELASDLLQIIKNSSPAFFEKLVVDLLVK  177

Query  179  MGYG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGA  236
            MGYG  R  A +    SGD GIDGII++D LGLD IY+QAKR+  + ++GRP+I +FAGA
Sbjct  178  MGYGGTRKDAGKTVGRSGDGGIDGIINEDRLGLDVIYIQAKRW--ENSVGRPEIQKFAGA  235

Query  237  LLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELL  296
            L G +  +GV+ITTS+F+  A++   RI+++I LIDG  L +L++   VGV      E+ 
Sbjct  236  LQGFRAKKGVFITTSTFTNEAKDYVSRIDSKIVLIDGEMLTQLMIENNVGVTPFTVYEVK  295

Query  297  RLDEDFF  303
            ++D D+F
Sbjct  296  KVDSDYF  302


>gi|34540717|ref|NP_905196.1| Mrr restriction system protein [Porphyromonas gingivalis W83]
 gi|34397031|gb|AAQ66095.1| Mrr restriction system protein [Porphyromonas gingivalis W83]
Length=305

 Score =  237 bits (605),  Expect = 2e-60, Method: Compositional matrix adjust.
 Identities = 120/305 (40%), Positives = 188/305 (62%), Gaps = 8/305 (2%)

Query  3    IPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVHWS  62
            IPD QTLM P+L  ++DGQ    +D+I  ++ EF ++D+ER ++L SG +    +RV W+
Sbjct  2    IPDFQTLMLPLLKCVSDGQEHKYRDIIEHLAAEFEVTDEERKELLASGSKAVFDNRVGWA  61

Query  63   LTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRE--RTKAKQP  120
             T++ +AGLLD P R  + ++D GR++L  +P ++D   LR FP++I F+   R   +  
Sbjct  62   RTYLKKAGLLDSPKRAILIISDLGREILSKNPPKIDTKYLRRFPAFIEFQNGYRNDGETE  121

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
             ++  ++      + +PE+++D A    R ++  E+L K + LSP  FE LV+ LL  MG
Sbjct  122  EESITEKIH----EQTPEEVLDKAYQRIRKSLASELLNKVIDLSPAFFERLVVELLVKMG  177

Query  181  YGRA--GAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG +   A +    SGD GIDG I +D LGLD IY+QAKR+     +GRP++ +F GAL 
Sbjct  178  YGGSIKDAGKALGKSGDEGIDGTIKEDKLGLDIIYIQAKRWRPGNVVGRPELQKFVGALA  237

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            G+   +G++ITTS+F++ A     R   +I LIDG +L +L++ Y +G    QT EL +L
Sbjct  238  GQGAKKGIFITTSNFTKEALTYTPRNETKIVLIDGEQLTQLMIDYNLGCTTQQTYELKKL  297

Query  299  DEDFF  303
            D D+F
Sbjct  298  DSDYF  302


>gi|75812373|ref|YP_319992.1| restriction endonuclease [Anabaena variabilis ATCC 29413]
 gi|75705129|gb|ABA24803.1| restriction endonuclease [Anabaena variabilis ATCC 29413]
Length=305

 Score =  237 bits (605),  Expect = 2e-60, Method: Compositional matrix adjust.
 Identities = 120/307 (40%), Positives = 193/307 (63%), Gaps = 9/307 (2%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD Q +M P+L +  D +  S ++ I A++D F L++DER ++LPSGRQ T  +RV 
Sbjct  1    MPIPDYQAIMLPLLKFTTDQKEHSLQETIDALADNFQLTEDERKELLPSGRQPTFNNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGL++   RG+ ++TD G   +K +P  ++   LR+FP ++ F+  T   Q 
Sbjct  61   WARTYLKKAGLVESTKRGYFRITDKGIDTIKTNPVEINAKFLRQFPEFLEFQNYT---QQ  117

Query  121  VDATAKRPSGDDVQV--SPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEA  178
             + +A   SG+++    +PE+ ++ A+ +    +  ++L+     SP  FE LV+ LL  
Sbjct  118  SEESASNGSGNEINTTRTPEEDVELAIQKLTKELASDLLQIIKNSSPAFFEKLVVDLLVK  177

Query  179  MGYG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGA  236
            MGYG  R  A +    SGD GIDGII++D LGLD IY+QAKR+  + ++GRP+I +FAGA
Sbjct  178  MGYGGTRKDAGKTVGRSGDGGIDGIINEDRLGLDVIYIQAKRW--ENSVGRPEIQKFAGA  235

Query  237  LLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELL  296
            L G +  +G++ITTS+F+  A++   RI+++I LIDG  L +L++   VGV      E  
Sbjct  236  LQGFRAKKGMFITTSTFTNEAKDYVSRIDSKIVLIDGEMLTQLMIENNVGVTPFTVYEAK  295

Query  297  RLDEDFF  303
            ++D D+F
Sbjct  296  KVDSDYF  302


>gi|188994846|ref|YP_001929098.1| putative Mrr restriction system protein [Porphyromonas gingivalis 
ATCC 33277]
 gi|188594526|dbj|BAG33501.1| putative Mrr restriction system protein [Porphyromonas gingivalis 
ATCC 33277]
Length=305

 Score =  237 bits (604),  Expect = 2e-60, Method: Compositional matrix adjust.
 Identities = 120/303 (40%), Positives = 187/303 (62%), Gaps = 4/303 (1%)

Query  3    IPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVHWS  62
            IPD QTLM P+L  ++DGQ    +D+I  ++ EF ++D+ER ++L SG Q    +RV W+
Sbjct  2    IPDFQTLMLPLLKCVSDGQEHKYRDIIEHLAAEFEVTDEERKELLASGSQAVFNNRVGWA  61

Query  63   LTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQPVD  122
             T++ +AGLLD P R  + ++D GR++L  +P ++D   LR FP++I F+     +   +
Sbjct  62   RTYLKKAGLLDSPKRAILIISDLGREILSKNPPKIDTKYLRRFPAFIEFQ--NGYRNDGE  119

Query  123  ATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMGYG  182
               +  + +  + +PE+++D A    R ++  E+L K + LSP  FE LV+ LL  MGYG
Sbjct  120  TEEESITEEIHEQTPEEVLDKAYQRIRKSLASELLNKVIDLSPAFFERLVVELLVKMGYG  179

Query  183  RA--GAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
             +   A +    SGD GIDG I +D LGLD IY+QAKR+     +GRP++ +F GAL G+
Sbjct  180  GSIKDAGKALGKSGDEGIDGTIKEDKLGLDIIYIQAKRWRPGNVVGRPELQKFVGALAGQ  239

Query  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300
               +G++ITTS+F++ A     R   +I LIDG +L +L++ Y +G    QT EL +LD 
Sbjct  240  GAKKGIFITTSNFTKEALTYTPRNETKIVLIDGEQLTQLMIDYNLGCTTQQTYELKKLDS  299

Query  301  DFF  303
            D+F
Sbjct  300  DYF  302


>gi|297625533|ref|YP_003687296.1| restriction system protein [Propionibacterium freudenreichii 
subsp. shermanii CIRM-BIA1]
 gi|296921298|emb|CBL55851.1| restriction system protein [Propionibacterium freudenreichii 
subsp. shermanii CIRM-BIA1]
Length=303

 Score =  235 bits (599),  Expect = 8e-60, Method: Compositional matrix adjust.
 Identities = 127/301 (43%), Positives = 179/301 (60%), Gaps = 6/301 (1%)

Query  10   MRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVHWSLTHMSQA  69
            M P L  LADG       V A ++D   ++ ++R ++LPSG+ R   +R +W+L+++ +A
Sbjct  1    MVPALRLLADGDIHRGNTVAAPVADALAITPEQREKLLPSGQPR-FANRANWALSYLYRA  59

Query  70   GLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQPVDATAKRPS  129
            G ++RPTR H ++TD GRQ+L +HP  +    LR  P Y+       A     A+    S
Sbjct  60   GAVERPTRAHYRITDVGRQLLASHPAGLTEHDLRAVPGYVIPSNHRNAASTSPASVPESS  119

Query  130  ----GDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMGY-GRA  184
                 +   +SP + I+  +      +  E+L +     P  FED V+ LLEAMGY G  
Sbjct  120  STIPAETAALSPTEQIEEGIERIHEELASELLGRLHDQDPAFFEDAVLSLLEAMGYPGTD  179

Query  185  GAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGKQGDR  244
            G + RT  S D GIDGI+ QD LGL R+YVQAKRY +D  +GRP +  FAGAL G   ++
Sbjct  180  GRITRTQLSRDGGIDGIVDQDALGLSRVYVQAKRYDLDAAVGRPTVQAFAGALQGNGANQ  239

Query  245  GVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDEDFFD  304
            GV+ TTS FS  AR+ AE++  R+ LIDGARLA L++RY VGVQ  +T E+  +DEDFF 
Sbjct  240  GVFFTTSRFSTDARDFAEKLPTRVVLIDGARLASLMIRYHVGVQVKKTYEIGEIDEDFFA  299

Query  305  G  305
            G
Sbjct  300  G  300


>gi|222525259|ref|YP_002569730.1| restriction endonuclease [Chloroflexus sp. Y-400-fl]
 gi|222449138|gb|ACM53404.1| restriction endonuclease [Chloroflexus sp. Y-400-fl]
Length=296

 Score =  234 bits (598),  Expect = 1e-59, Method: Compositional matrix adjust.
 Identities = 130/305 (43%), Positives = 191/305 (63%), Gaps = 14/305 (4%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD QT+M P+L  +ADGQ  S + ++  +++ F LS++E  ++LPSG+Q   Y+RV 
Sbjct  1    MPIPDFQTIMLPMLRVMADGQEHSIQGLLDRLAETFSLSEEELRELLPSGKQTLFYNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++++AGLL+   R + ++T  G+QVL+ +P R+D+  L +FP Y+ FR R K    
Sbjct  61   WARTYLAKAGLLETTRRSYYRITARGQQVLQQNPSRIDIRFLEQFPEYLEFRRRPKLT--  118

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
                      ++ + +PE++++ A  E R  +  E+LK      P  FE LV+ LL  MG
Sbjct  119  --------IFEEKEQTPEEVLEDAYQEIRNNLAQELLKLVKQSPPAFFERLVVELLVNMG  170

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG  R  A       GD GIDGII +D LGLD IY+QAKR+  D  +GRP+I +F GAL+
Sbjct  171  YGGSRRDAARAVGQVGDEGIDGIIDEDRLGLDTIYIQAKRW--DNVVGRPEIQKFVGALM  228

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            GK+  +G++ITTS+FS  A      I+ +I LIDG RLAEL++ Y VGV  V T +L R+
Sbjct  229  GKRARKGIFITTSTFSAEAINYVANIDTKIVLIDGKRLAELMIDYDVGVATVSTYQLKRV  288

Query  299  DEDFF  303
            D D+F
Sbjct  289  DSDYF  293


>gi|334146688|ref|YP_004509616.1| Mrr restriction system protein [Porphyromonas gingivalis TDC60]
 gi|333803843|dbj|BAK25050.1| Mrr restriction system protein [Porphyromonas gingivalis TDC60]
Length=305

 Score =  234 bits (597),  Expect = 1e-59, Method: Compositional matrix adjust.
 Identities = 119/303 (40%), Positives = 187/303 (62%), Gaps = 4/303 (1%)

Query  3    IPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVHWS  62
            IPD QTLM P+L  ++DGQ    +D+I  ++ EF ++D+ER ++L SG +    +RV W+
Sbjct  2    IPDFQTLMLPLLKCVSDGQEHKYRDIIEHLAAEFEVTDEERKELLASGSKAVFDNRVGWA  61

Query  63   LTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQPVD  122
             T++ +AGLLD P R  + ++D GR++L  +P ++D   LR FP++I F+     +   +
Sbjct  62   RTYLKKAGLLDSPKRAILIISDLGREILSKNPPKIDTKYLRRFPAFIEFQ--NGYRNDGE  119

Query  123  ATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMGYG  182
               +  + +  + +PE+++D A    R ++  E+L K + LSP  FE LV+ LL  MGYG
Sbjct  120  TEEESITEEIHEQTPEEVLDKAYQRIRKSLASELLNKVIDLSPAFFERLVVELLVKMGYG  179

Query  183  RA--GAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLGK  240
             +   A +    SGD GIDG I +D LGLD IY+QAKR+     +GRP++ +F GAL G+
Sbjct  180  GSIKDAGKALGKSGDEGIDGTIKEDKLGLDIIYIQAKRWRPGNVVGRPELQKFVGALAGQ  239

Query  241  QGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRLDE  300
               +G++ITTS+F++ A     R   +I LIDG +L +L++ Y +G    QT EL +LD 
Sbjct  240  GAKKGIFITTSNFTKEALTYTPRNETKIVLIDGEQLTQLMIDYNLGCTTQQTYELKKLDS  299

Query  301  DFF  303
            D+F
Sbjct  300  DYF  302


>gi|163847411|ref|YP_001635455.1| restriction endonuclease [Chloroflexus aurantiacus J-10-fl]
 gi|163668700|gb|ABY35066.1| restriction endonuclease [Chloroflexus aurantiacus J-10-fl]
Length=304

 Score =  234 bits (597),  Expect = 1e-59, Method: Compositional matrix adjust.
 Identities = 130/305 (43%), Positives = 191/305 (63%), Gaps = 14/305 (4%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD QT+M P+L  +ADGQ  S + ++  +++ F LS++E  ++LPSG+Q   Y+RV 
Sbjct  9    MPIPDFQTIMLPMLRVMADGQEHSIQGLLDRLAETFSLSEEELRELLPSGKQTLFYNRVG  68

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++++AGLL+   R + ++T  G+QVL+ +P R+D+  L +FP Y+ FR R K    
Sbjct  69   WARTYLAKAGLLETTRRSYYRITARGQQVLQQNPSRIDIRFLEQFPEYLEFRRRPKLT--  126

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
                      ++ + +PE++++ A  E R  +  E+LK      P  FE LV+ LL  MG
Sbjct  127  --------IFEEKEQTPEEVLEDAYQEIRNNLAQELLKLVKQSPPAFFERLVVELLVNMG  178

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG  R  A       GD GIDGII +D LGLD IY+QAKR+  D  +GRP+I +F GAL+
Sbjct  179  YGGSRRDAARAVGQVGDEGIDGIIDEDRLGLDTIYIQAKRW--DNVVGRPEIQKFVGALM  236

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            GK+  +G++ITTS+FS  A      I+ +I LIDG RLAEL++ Y VGV  V T +L R+
Sbjct  237  GKRARKGIFITTSTFSAEAINYVANIDTKIVLIDGKRLAELMIDYDVGVATVSTYQLKRV  296

Query  299  DEDFF  303
            D D+F
Sbjct  297  DSDYF  301


>gi|251771181|gb|EES51763.1| restriction endonuclease [Leptospirillum ferrodiazotrophum]
Length=302

 Score =  234 bits (596),  Expect = 2e-59, Method: Compositional matrix adjust.
 Identities = 125/307 (41%), Positives = 192/307 (63%), Gaps = 9/307 (2%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD Q++MRPIL    DG+  S +++I  +S  F LS+++R  +  SG Q T Y+R  
Sbjct  1    MAIPDFQSIMRPILELSKDGKNHSIRELIEPLSVRFHLSEEDRNALNASG-QTTFYNRAA  59

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ TH+ QAGLL+   RG+ ++T+ G   L+  PER+DMA L ++  +  FR+R   K+ 
Sbjct  60   WAKTHLKQAGLLEPVQRGYFRITERGLNALREAPERIDMAFLLQYKEFADFRQR---KRT  116

Query  121  VDATAKRP-SGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAM  179
             D   +    G +  ++PE+ ++ A  + R  +E E+L+   T SP+ FE +V+ +L  M
Sbjct  117  NDTEPEHDLGGANNLLTPEESVETAFKKFRQELEAELLQTLKTCSPSLFERIVVDVLVKM  176

Query  180  GYG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGAL  237
            GYG  R  A +    SGD GIDG+I +D LGLD IY+QAK++  + T+ RP+I +FAGAL
Sbjct  177  GYGGNRQDAGQAIGKSGDGGIDGLIKEDRLGLDTIYIQAKKW--EGTVSRPEIQKFAGAL  234

Query  238  LGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLR  297
             G +  +GV+ITTSSF++ ARE    +  +I LIDG RL + ++ + VGV  + T E  +
Sbjct  235  QGMRAKKGVFITTSSFTKEAREYVAHLENKIILIDGERLTQYMIDFNVGVSIIGTYETKK  294

Query  298  LDEDFFD  304
            +D D+F+
Sbjct  295  IDLDYFE  301


>gi|153003951|ref|YP_001378276.1| restriction endonuclease [Anaeromyxobacter sp. Fw109-5]
 gi|152027524|gb|ABS25292.1| restriction endonuclease [Anaeromyxobacter sp. Fw109-5]
Length=304

 Score =  232 bits (591),  Expect = 6e-59, Method: Compositional matrix adjust.
 Identities = 132/305 (44%), Positives = 183/305 (60%), Gaps = 6/305 (1%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M +PD ++ M P+L  + DG     +DV   ++ EF L+  ERA+MLPSG+Q    +RV 
Sbjct  1    MPVPDYESFMLPLLRAVGDGDEHHVRDVRDRLAAEFNLTAQERAEMLPSGKQSVFDNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGL+    RG  Q+T  GR VL   P  +  + L  F  +  F    +    
Sbjct  61   WAKTYLDKAGLISSVRRGVYQITKEGRSVLTERPREITKSYLERFEPFREFLT-LRHNGD  119

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
            VD ++  PS D  + +PE+ ++ A    R   E ++L    T SP  FE LVI LL  MG
Sbjct  120  VDESSFSPSTDPTE-TPEEQLEVAYRRIRQKTEADVLAAVKTASPQFFEKLVIELLVKMG  178

Query  181  YGR--AGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG   A A E    +GD GIDG+I +D LGLD IYVQAKR+    T+GRP I  FAG+LL
Sbjct  179  YGGTIADAGEALGRTGDGGIDGVIKEDKLGLDAIYVQAKRW--QNTVGRPDIQGFAGSLL  236

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            G++G +GV+ITTS+FS+ ARE   +I A+I LIDGA LA L+V + VGV  V+T  + R+
Sbjct  237  GRRGRKGVFITTSAFSKEAREYVGQIEAKIILIDGATLAGLMVDHDVGVNTVETYAVKRV  296

Query  299  DEDFF  303
            D D+F
Sbjct  297  DSDYF  301


>gi|257058969|ref|YP_003136857.1| restriction endonuclease [Cyanothece sp. PCC 8802]
 gi|256589135|gb|ACV00022.1| restriction endonuclease [Cyanothece sp. PCC 8802]
Length=310

 Score =  231 bits (589),  Expect = 1e-58, Method: Compositional matrix adjust.
 Identities = 121/311 (39%), Positives = 194/311 (63%), Gaps = 11/311 (3%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M+IPD Q+++ P+L Y  D Q  S ++ I  ++  F L+D+E+ ++LPSG+Q    +RV 
Sbjct  1    MSIPDFQSILLPLLKYSGDKQEHSLRESIEYLAGIFNLTDEEKRELLPSGQQAIFDNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +A L++   RG+ ++TD G  VL+ + +++D   L++F  +  F   TK K+ 
Sbjct  61   WAKTYLKKAHLIETTKRGYFRITDQGITVLQQNYQKIDTNFLKQFEEFNEFHLGTKTKKD  120

Query  121  VDATAKRPS------GDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIR  174
                ++          D +Q +PE+L+D    + +  ++ EIL++ +  SP  FE LVI 
Sbjct  121  STNNSENSELSCLSLNDQIQ-TPEELLDQLYQKIKDDLKQEILEQIMRCSPEFFERLVID  179

Query  175  LLEAMGYG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHE  232
            LL  MGYG  +  A E    + D GIDGII +D LGLD IY+QAKR+  + T+GRP+I +
Sbjct  180  LLIRMGYGGSKKEAGEAVGKAKDGGIDGIIKEDRLGLDIIYIQAKRW--EGTVGRPEIQK  237

Query  233  FAGALLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQT  292
            F GALLG+Q  +G++ITTS FS+ A+E    I+++I LI G  L+ELL  Y VGV  +++
Sbjct  238  FVGALLGQQAKKGIFITTSQFSKEAKEYVAIIDSKIILISGDLLSELLSDYNVGVSVIKS  297

Query  293  VELLRLDEDFF  303
             E+ ++D D+F
Sbjct  298  YEIKKIDTDYF  308


>gi|254466305|ref|ZP_05079716.1| Mrr restriction system protein [Rhodobacterales bacterium Y4I]
 gi|206687213|gb|EDZ47695.1| Mrr restriction system protein [Rhodobacterales bacterium Y4I]
Length=321

 Score =  230 bits (586),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 125/308 (41%), Positives = 189/308 (62%), Gaps = 7/308 (2%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M+IPD QT M P+L    +G+ K +  VI  +S+EF L++DE+A++LPSG+Q  + +R+H
Sbjct  14   MSIPDYQTFMLPVLKKSQNGEVKIST-VIEELSEEFNLTEDEKAELLPSGKQTIVANRIH  72

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ QAGL++   R H  ++D GR VL  +P+ +D  +L EF  +  F+ R +  Q 
Sbjct  73   WAKTYLKQAGLIEATRRAHFVISDRGRAVLAKNPDAIDARMLEEFDEFQDFKNR-RGTQD  131

Query  121  VDATAKRPSGDDVQVS---PEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLE  177
               T    +   V+ S   P++++ AA  +    +  E+L+K  T SP  FE LV+ LL 
Sbjct  132  TSRTQSDDNDSPVESSSKTPDEIMRAAHRKIEDTLRAEMLEKIRTASPAFFEGLVVNLLV  191

Query  178  AMGYGRA--GAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAG  235
            AMGYG +   A      +GD G+DG+I QD LGLDR+Y+QAKRY     +G   I +F G
Sbjct  192  AMGYGGSVTDAGRAIGRAGDGGVDGVIDQDALGLDRVYIQAKRYGDGNNVGPGAIRDFFG  251

Query  236  ALLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVEL  295
            +L   +  +G+++TTS+F+  A E A+ ++ RI LID   L +L+VRY VG +   T+ L
Sbjct  252  SLDRFKATKGLFVTTSAFTNEAVETAQLLSKRIVLIDSETLTKLMVRYNVGCRVEDTLFL  311

Query  296  LRLDEDFF  303
             RLDEDFF
Sbjct  312  RRLDEDFF  319


>gi|218245921|ref|YP_002371292.1| restriction endonuclease [Cyanothece sp. PCC 8801]
 gi|218166399|gb|ACK65136.1| restriction endonuclease [Cyanothece sp. PCC 8801]
Length=310

 Score =  230 bits (586),  Expect = 2e-58, Method: Compositional matrix adjust.
 Identities = 120/311 (39%), Positives = 194/311 (63%), Gaps = 11/311 (3%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M+IPD Q+++ P+L Y  D Q  S ++ I  ++  F L+D+E+ ++LPSG+Q    +RV 
Sbjct  1    MSIPDFQSILLPLLKYSGDKQEHSLRESIEYLAGIFNLTDEEKRELLPSGQQAIFDNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +A L++   RG+ ++TD G  VL+ + +++D   L++F  +  F   TK K+ 
Sbjct  61   WAKTYLKKAHLIETTKRGYFRITDQGITVLQQNYQKIDTNFLKQFEEFNEFHLGTKTKKD  120

Query  121  VDATAKRPS------GDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIR  174
                ++          D +Q +PE+L+D    + +  ++ EIL++ +  SP  FE LVI 
Sbjct  121  STNNSENSELSCLSLNDQIQ-TPEELLDQLYQKIKDDLKQEILEQIMRCSPEFFERLVID  179

Query  175  LLEAMGYG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHE  232
            LL  MGYG  +  A +    + D GIDGII +D LGLD IY+QAKR+  + T+GRP+I +
Sbjct  180  LLIKMGYGGSKKEAGKAVGKAKDGGIDGIIKEDRLGLDIIYIQAKRW--EGTVGRPEIQK  237

Query  233  FAGALLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQT  292
            F GALLG+Q  +G++ITTS FS+ A+E    I+++I LI G  L+ELL  Y VGV  +++
Sbjct  238  FVGALLGQQAKKGIFITTSQFSKEAKEYVAIIDSKIILISGDLLSELLSDYNVGVSVIKS  297

Query  293  VELLRLDEDFF  303
             E+ ++D D+F
Sbjct  298  YEIKKIDTDYF  308


>gi|270157736|ref|ZP_06186393.1| Mrr restriction system protein [Legionella longbeachae D-4968]
 gi|269989761|gb|EEZ96015.1| Mrr restriction system protein [Legionella longbeachae D-4968]
Length=304

 Score =  230 bits (586),  Expect = 3e-58, Method: Compositional matrix adjust.
 Identities = 112/306 (37%), Positives = 183/306 (60%), Gaps = 8/306 (2%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IP+ QT M P+L  +   +      +I  ++++F  S DE+ +M+PSG+   +  R+ 
Sbjct  1    MAIPNYQTFMLPVLKSVKGNEPLKYSTLIELVTNQFNFSPDEKKEMIPSGKTTVLKSRIG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ +++ QAGLL  P RG + +T  G  VL   PE +D   L++FP ++AF +R  +   
Sbjct  61   WAKSYLKQAGLLFYPKRGFISLTPIGNNVLAKSPETIDTNYLKQFPDFLAFLDRNSSSNK  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
               T   P       +P++L++      ++ +  E++    T SP  FE LVI ++ +MG
Sbjct  121  QLNTDTDPH----DATPDELMEQTYNTLKSKILDELIDTIKTCSPQFFEQLVIDVIVSMG  176

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG  R  A +    +GD GIDG++++D LGLD IY+QAKR+  +  +GRP+I +F GAL 
Sbjct  177  YGGSRREAGKAIGQTGDEGIDGVVNEDRLGLDVIYLQAKRW--EAVVGRPEIQKFVGALQ  234

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            GK+  +G++ITTS F++GA+E  E I+ +I L+ G +LAEL+  Y +G+    T E+  L
Sbjct  235  GKRAKKGIFITTSGFTKGAQEFVEHIDCKIILLSGIQLAELMWEYNIGLNHSATYEIKSL  294

Query  299  DEDFFD  304
            D+D+F+
Sbjct  295  DQDYFN  300


>gi|302343460|ref|YP_003807989.1| restriction endonuclease [Desulfarculus baarsii DSM 2075]
 gi|301640073|gb|ADK85395.1| restriction endonuclease [Desulfarculus baarsii DSM 2075]
Length=308

 Score =  229 bits (585),  Expect = 3e-58, Method: Compositional matrix adjust.
 Identities = 125/311 (41%), Positives = 191/311 (62%), Gaps = 14/311 (4%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD Q++M P+L YLAD    S +D+  A+  +F ++D+E+A++LPSG+QR   +R+ 
Sbjct  1    MPIPDFQSIMLPLLRYLADEMVHSNQDIYEALESQFTMTDEEKAELLPSGKQRVFINRIG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHP-ERVDMAVLREFPSYIAFR-----ER  114
            W+ ++M QAGL+D   RG  +++ TG+ V      +++ +  L +FPS++ FR       
Sbjct  61   WAKSYMKQAGLIDAAGRGFYKISKTGKAVAADKSLDKIGINYLLKFPSFVTFRVGKGVSA  120

Query  115  TKAKQPVDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIR  174
            + A Q  D       G+    + E+ I   +      ++ E++      SP  FE LV+ 
Sbjct  121  SIAAQDTDCG----DGNSPDRTAEEHIGLGVDTIMLKLKQELMSNIKACSPRFFEKLVVD  176

Query  175  LLEAMGYG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHE  232
            LL AMGYG  R  +   T    D GIDG+I++D LGLD IYVQAKR+  +  +GRP+I +
Sbjct  177  LLLAMGYGGSRQESGMLTGKGSDEGIDGVINEDRLGLDVIYVQAKRW--EHAVGRPEIQK  234

Query  233  FAGALLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQT  292
            FAGAL GK+  +GVYITTS F++ A + A  I+++I L+DG RLA L+V + VGV  VQ+
Sbjct  235  FAGALQGKRAKKGVYITTSCFTKDAYDFAGAIDSKIILVDGERLAGLMVEHNVGVAVVQS  294

Query  293  VELLRLDEDFF  303
            +EL ++D D+F
Sbjct  295  IELKKVDMDYF  305


>gi|295696350|ref|YP_003589588.1| restriction endonuclease [Bacillus tusciae DSM 2912]
 gi|295411952|gb|ADG06444.1| restriction endonuclease [Bacillus tusciae DSM 2912]
Length=308

 Score =  229 bits (584),  Expect = 4e-58, Method: Compositional matrix adjust.
 Identities = 121/306 (40%), Positives = 190/306 (63%), Gaps = 7/306 (2%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M++PD Q++M P+L    D +     +VI  +S +F L+D +R ++LPSGRQ    +RV 
Sbjct  1    MSVPDYQSIMLPLLKITEDCREHRLNEVIETLSSQFLLTDSDRKELLPSGRQPKFDNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGLL+   RG  ++T+ G +VL+ +P  ++   L +FP ++ F+ RT  +  
Sbjct  61   WARTYLVKAGLLESTGRGKFRITERGLEVLRTNPNEINNRFLSQFPEFLEFKNRTSTQGA  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
             D  A   S D    +PE+++D+     R ++  E+L++    +P  FE LV+ LL AMG
Sbjct  121  DDNDADLESLDR---TPEEILDSTHLSLRKSLADELLERIKNCTPKFFERLVVDLLVAMG  177

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG  R  A +    SGD GIDG+I++D LGLD IY+QAKR+  + T+GRP +  FAG+L 
Sbjct  178  YGGSRVDAGQALGQSGDDGIDGMINEDRLGLDVIYLQAKRW--EGTVGRPIVQAFAGSLE  235

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            G++  +G+ ITTS FS+ A+E   RI  +I LIDG +LA L++ + VGV  V    + ++
Sbjct  236  GQRARKGILITTSRFSQDAKEYVTRIEKKIVLIDGEQLANLMIDFNVGVTEVTRYVIKKV  295

Query  299  DEDFFD  304
            D D+FD
Sbjct  296  DLDYFD  301


>gi|344339026|ref|ZP_08769956.1| restriction endonuclease [Thiocapsa marina 5811]
 gi|343800946|gb|EGV18890.1| restriction endonuclease [Thiocapsa marina 5811]
Length=304

 Score =  228 bits (582),  Expect = 7e-58, Method: Compositional matrix adjust.
 Identities = 127/305 (42%), Positives = 186/305 (61%), Gaps = 6/305 (1%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD Q++M P+L + ADG   + +  + A+  EF L++DE+ ++LPSG+QR + +RV 
Sbjct  1    MAIPDFQSIMLPLLRFCADGNEHTNQKALEALVQEFQLNEDEQKELLPSGQQRVIDNRVA  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+  HM  A LL+   RG  ++TD G+ VLK  P  +++ +LR+FP Y+A R++ K + P
Sbjct  61   WARAHMKMAELLENTRRGVFRITDRGQDVLKGMPSEINLRLLRQFPEYVAARDKRK-ENP  119

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
             D         + + +P + ++AA    R  +  EIL +    S   FE +V+ +L  MG
Sbjct  120  GDQDCSDFEEREGK-TPAEQLEAAYQTLRENLAAEILAQLKGGSAMFFERVVVEVLVKMG  178

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG  R  A E    SGD GIDGII +D LGLD IY+QAK++  +  I RP+I +FAGAL 
Sbjct  179  YGGSRKDAGEAIGRSGDEGIDGIIKEDRLGLDIIYIQAKKW--EDPISRPEIQKFAGALQ  236

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            GK+  +GV+ITTS F   A+E A  I  +I LIDG +LA+ ++ + VGV      EL RL
Sbjct  237  GKRARKGVFITTSRFCETAKEFAANIENKIILIDGQQLAQFMIDFGVGVATDAVYELKRL  296

Query  299  DEDFF  303
            D D+F
Sbjct  297  DSDYF  301


>gi|320104887|ref|YP_004180478.1| restriction endonuclease [Isosphaera pallida ATCC 43644]
 gi|319752169|gb|ADV63929.1| restriction endonuclease [Isosphaera pallida ATCC 43644]
Length=307

 Score =  228 bits (582),  Expect = 7e-58, Method: Compositional matrix adjust.
 Identities = 125/306 (41%), Positives = 185/306 (61%), Gaps = 5/306 (1%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M +PD Q++M P+L  L +G+  + +D+ A ++D F L+ ++R QMLPSG Q    +RV 
Sbjct  1    MPVPDFQSIMLPLLEALQNGEEVAVRDLTALLADRFMLTPEDRQQMLPSGEQTVFNNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ TH+  AGL+D PTRG V++T+ G +VL   P  V+   L+ FP+Y+ F  +   K  
Sbjct  61   WAKTHLKNAGLIDNPTRGRVRITEVGMKVLAEKPATVNCRFLKRFPTYLKFTGQGAGKGG  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
             +      + +  Q +P++L+DA+    R A   E+L +    S   FE +V+RLL AMG
Sbjct  121  AEVGPNETTPETSQ-TPQELLDASYHALRKATLEELLIRLKACSSGHFEKVVVRLLLAMG  179

Query  181  YGR-AGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALLG  239
            YG  AG    T  SGD GIDG+I +D LGLD + +QAKR+  + T+GRP I  F G++  
Sbjct  180  YGGVAGDGTVTGKSGDGGIDGMIKEDKLGLDVVCLQAKRW--EGTVGRPIIQGFVGSMDY  237

Query  240  KQGDRGVYITTSSFSRGAREEAERINA-RIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
             +  +GV ITTS FSR A+E  +RI   ++ LIDG  LA+L++ + VGV   +  EL  +
Sbjct  238  IRAKKGVIITTSQFSRDAQEFVDRIEGKKVVLIDGPTLADLMIEHNVGVTTTRRYELKDV  297

Query  299  DEDFFD  304
              DFFD
Sbjct  298  SNDFFD  303


>gi|237755764|ref|ZP_04584368.1| Mrr restriction system protein [Sulfurihydrogenibium yellowstonense 
SS-5]
 gi|237692074|gb|EEP61078.1| Mrr restriction system protein [Sulfurihydrogenibium yellowstonense 
SS-5]
Length=302

 Score =  228 bits (580),  Expect = 1e-57, Method: Compositional matrix adjust.
 Identities = 118/308 (39%), Positives = 187/308 (61%), Gaps = 14/308 (4%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IP  Q LM P+L  ++DG+  S ++VI  +++EF LS+++R + LPSGRQR   +RV+
Sbjct  1    MAIPGYQDLMLPLLKLVSDGKEYSLREVIERLAEEFNLSEEDRNEFLPSGRQRVFDNRVN  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHP--ERVDMAVLREFPSYIAFRERTKAK  118
            W+ T++ +AGLL+ P RG ++++  G+Q L  +P  +++    L +F S+  F  R   +
Sbjct  61   WAKTYLLKAGLLESPKRGCIKISKVGKQFLADNPYLDKLTNKDLMQFESFKEFISRGNEE  120

Query  119  QPVDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEA  178
                    +        +P ++I+  + E   A+  E+L+K    SP  FE LVI LL  
Sbjct  121  NAAPHIDPK--------TPTEIIEQKIQEVNEALADELLRKIKNSSPKFFEKLVIDLLLK  172

Query  179  MGYG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGA  236
            MGYG       E    SGD GIDG I +D LGLD IY+QAKR+  +  +GRP+I +F GA
Sbjct  173  MGYGGSEKEMAEVVGKSGDEGIDGTIKEDKLGLDVIYIQAKRW--EGPVGRPEIQKFVGA  230

Query  237  LLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELL  296
            L GK+  +GV+ TTS+F+  A++    +  ++ LIDG +LA+L+++Y VGV   + +E+ 
Sbjct  231  LAGKKAKKGVFFTTSTFTDEAKDYVSHLEQKVVLIDGNKLADLMIKYNVGVSVERVIEIK  290

Query  297  RLDEDFFD  304
            R+D D+F+
Sbjct  291  RIDSDYFE  298


>gi|119471839|ref|ZP_01614172.1| methylated adenine and cytosine restriction protein [Alteromonadales 
bacterium TW-7]
 gi|119445329|gb|EAW26618.1| methylated adenine and cytosine restriction protein [Alteromonadales 
bacterium TW-7]
Length=309

 Score =  228 bits (580),  Expect = 1e-57, Method: Compositional matrix adjust.
 Identities = 117/308 (38%), Positives = 187/308 (61%), Gaps = 5/308 (1%)

Query  3    IPDAQTLMRPIL--AYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            IP+ Q  MRP L  A+ A G+    +DVI  ++++F L+D+E+ + LPSGRQ  + +RV 
Sbjct  2    IPNYQQFMRPFLEVAHRAHGREVKLRDVINELAEQFNLTDEEKTETLPSGRQPILDNRVG  61

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++++AGLL+   R H  +T  G + L+     +D   L++F  ++AF E+      
Sbjct  62   WARTYLTKAGLLEATRRAHFVITTRGIKALEDESTVIDKNYLKQFDEFVAFSEQKNEAAV  121

Query  121  VDATAKRPSGDDVQ-VSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAM  179
            + A     S D+++ ++P++ +  A      A+  ++L +   ++P  FE+L+I LL AM
Sbjct  122  ITAPINPQSNDNIEDITPDEALRNAYKAINDALTSDLLSRTRKVTPAFFEELLIELLIAM  181

Query  180  GYGRAG--AVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGAL  237
            GYG  G  A      +GD GIDG+I QDPLG+D+IY+QAKRYA    +G   I +F GAL
Sbjct  182  GYGGTGEGAAHALGKTGDNGIDGVIDQDPLGVDQIYIQAKRYAKGNNVGAGDIRDFFGAL  241

Query  238  LGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLR  297
              K+  +G++ITTS F+  A E A+ +  RI LI+G  LA L++RY +G +  Q + L +
Sbjct  242  NLKKAQKGIFITTSEFTSSAIETAQNLGTRIVLINGTELANLMLRYSIGSRDEQVLHLKK  301

Query  298  LDEDFFDG  305
            +DE+FF+ 
Sbjct  302  IDEEFFEN  309


>gi|338536845|ref|YP_004670179.1| restriction endonuclease [Myxococcus fulvus HW-1]
 gi|337262941|gb|AEI69101.1| restriction endonuclease [Myxococcus fulvus HW-1]
Length=305

 Score =  226 bits (577),  Expect = 3e-57, Method: Compositional matrix adjust.
 Identities = 125/308 (41%), Positives = 188/308 (62%), Gaps = 12/308 (3%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD Q+ M P+L    DG+  +  + + A++ EF  + +ER ++LPSGRQR +++RV 
Sbjct  1    MPIPDFQSAMLPVLRLAQDGKDHTLGEAVEAIAVEFKATAEERNELLPSGRQRRIHNRVG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGL++   RG  ++T  G++VL+  P R+DM  L +FP Y AF     A   
Sbjct  61   WAKTYLQKAGLVEPNGRGRFRITSRGQEVLQRKPNRIDMKFLEQFPEYNAF-----AALR  115

Query  121  VDATAKRPSGDDVQV---SPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLE  177
             DA    PS  ++     +PE++++ +  E R  +  E+L++     P  FE LV+ LL 
Sbjct  116  HDAAEAEPSTPELSSATETPEEILEESYQELRRRLADELLERIKACDPKFFEKLVVDLLV  175

Query  178  AMGYG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAG  235
            AMGYG  R  A +    SGD GIDGII +D LGLD +Y+QAKR+     +GRP +  F G
Sbjct  176  AMGYGGSRKDAGQAVGQSGDEGIDGIIKEDRLGLDVVYIQAKRWT--NNVGRPVVQAFTG  233

Query  236  ALLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVEL  295
            +L G++  +GV ITTS FSR AR+  ++I  +I LIDG  LA+L++ + VGV  V T  +
Sbjct  234  SLEGQRARKGVLITTSDFSREARDYVKQIEKKIVLIDGVELAKLMIDHGVGVTEVATYTV  293

Query  296  LRLDEDFF  303
             +LD D+F
Sbjct  294  KKLDLDYF  301


>gi|323136815|ref|ZP_08071896.1| restriction endonuclease [Methylocystis sp. ATCC 49242]
 gi|322398132|gb|EFY00653.1| restriction endonuclease [Methylocystis sp. ATCC 49242]
Length=304

 Score =  226 bits (577),  Expect = 3e-57, Method: Compositional matrix adjust.
 Identities = 119/306 (39%), Positives = 192/306 (63%), Gaps = 4/306 (1%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M+IPD Q+LM P+L   A G+ +   +VI  + D+  LS ++R+Q+LPSG Q    +RVH
Sbjct  1    MSIPDYQSLMLPVLLACAGGETRIG-EVIEKLGDQLALSPEDRSQLLPSGAQTVFANRVH  59

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGL++   RG+ Q+T  GR+V+   P R+D A LR+F  +  F   +  K  
Sbjct  60   WAKTYLGKAGLVESTRRGYFQITARGREVVAKKPVRIDNAFLRQFEEFEKFTRGSPEKSS  119

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
             D  A  P+  +V+ +P++L+  A  +  A++  ++L++     P  FE L++ LL +MG
Sbjct  120  HDQGASEPA-VEVEETPDELMRLAHKKIEASLARDLLERVRKAPPDFFERLIVSLLLSMG  178

Query  181  YGRA--GAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG +   A      SGD G+DG+I QD LGLDR+Y+QAKRY    +IG   I +F G+L 
Sbjct  179  YGGSVTDAGRALGRSGDDGVDGVIDQDALGLDRVYIQAKRYGEGNSIGSGAIRDFFGSLD  238

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
              +  +G+++TTS FS  A E A+ ++ RI LIDG +L++L++R+ VG +   T+++ ++
Sbjct  239  RHKATKGLFVTTSGFSPSAIETAQYLSKRIVLIDGVQLSKLMIRHNVGCRVEDTLQIKKI  298

Query  299  DEDFFD  304
            DEDFF+
Sbjct  299  DEDFFE  304


>gi|336115221|ref|YP_004569988.1| restriction endonuclease [Bacillus coagulans 2-6]
 gi|335368651|gb|AEH54602.1| restriction endonuclease [Bacillus coagulans 2-6]
Length=306

 Score =  226 bits (576),  Expect = 4e-57, Method: Compositional matrix adjust.
 Identities = 116/306 (38%), Positives = 184/306 (61%), Gaps = 4/306 (1%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MT+PD QT M P L  L D    + +++   ++D F L+D ++ + LPSG+Q    +R+ 
Sbjct  1    MTVPDYQTFMLPFLKILGDRNEHTLQEMYIKLADYFSLTDADKKEYLPSGKQLKYKNRIG  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGLL++  RG   +++ G  VL  +PE++D+  L  F  +  FR    +   
Sbjct  61   WARTYLKKAGLLEQVGRGRFTISEQGLSVLNKNPEKIDVKFLERFNEFREFRSNKNSTDH  120

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
             D+T   P+  +  +SPE+++D++  +   ++  E+L+   + SP  FE LV+ LL AMG
Sbjct  121  KDSTETLPNNRESDLSPEEILDSSFRDITRSLMDELLRTVKSCSPEFFEKLVVDLLVAMG  180

Query  181  YG--RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGALL  238
            YG   A A +    +GD GIDGII +D LGLD IY+QAKR+  + ++GRP +  FAG+L 
Sbjct  181  YGGTHADAGQAIGRTGDDGIDGIIKEDKLGLDVIYIQAKRW--EGSVGRPVVQAFAGSLE  238

Query  239  GKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLRL  298
            G +  +GV ITTS F+  A++  +RI  +I LIDG  LAEL++   VGV    T  +  +
Sbjct  239  GNRARKGVLITTSRFTEEAKDYVKRIEKKIVLIDGETLAELMIDNNVGVSPKITYIIKDI  298

Query  299  DEDFFD  304
            D D+F+
Sbjct  299  DSDYFN  304


>gi|330997041|ref|ZP_08320903.1| restriction endonuclease [Paraprevotella xylaniphila YIT 11841]
 gi|329571539|gb|EGG53221.1| restriction endonuclease [Paraprevotella xylaniphila YIT 11841]
Length=306

 Score =  226 bits (576),  Expect = 4e-57, Method: Compositional matrix adjust.
 Identities = 121/307 (40%), Positives = 181/307 (59%), Gaps = 10/307 (3%)

Query  3    IPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVHWS  62
            IPD Q+ M P L  L DG   S  ++  A+  EF L++ +  +MLPS R       V W+
Sbjct  2    IPDFQSCMLPFLRKLEDGSVHSMTEIQNALIREFHLTETDVKEMLPSNRTTRFRSNVGWA  61

Query  63   LTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQPVD  122
             THM +AGLL+ P R   ++T+ G ++L+  PE ++M +L  +P+Y  +   +       
Sbjct  62   KTHMQKAGLLETPQRAQYRITEAGLRLLQTRPEHINMKLLFNYPAYKEWIALSNRNSEPK  121

Query  123  ATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMGYG  182
              +++ S   +Q +P+ +++    + R  +  ++L++ L   P  FE LVI+LL AMGYG
Sbjct  122  RNSRQESECAIQ-TPDIIMEEEYKKLRNILAQDLLERILKKDPGFFEALVIKLLVAMGYG  180

Query  183  -----RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGAL  237
                  AG V     SGD GIDGII +D LGLD IY+QAKR+  +  + RP++ +F GAL
Sbjct  181  GSLNEAAGMV--VGKSGDEGIDGIIKEDKLGLDNIYIQAKRW--NNVVERPEVQKFVGAL  236

Query  238  LGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLR  297
             GK   +G++ITTSSFSRGARE   + N +I LIDG +L E ++ Y +GV    T E+ R
Sbjct  237  AGKGATKGIFITTSSFSRGAREFKPQNNIKIVLIDGNQLCEYMIDYNIGVFTANTFEVKR  296

Query  298  LDEDFFD  304
            +D DFF+
Sbjct  297  IDIDFFE  303


>gi|148358355|ref|YP_001249562.1| Mrr restriction system protein [Legionella pneumophila str. Corby]
 gi|148280128|gb|ABQ54216.1| Mrr restriction system protein (EcoKMrr) [Legionella pneumophila 
str. Corby]
Length=325

 Score =  225 bits (574),  Expect = 5e-57, Method: Compositional matrix adjust.
 Identities = 118/306 (39%), Positives = 181/306 (60%), Gaps = 7/306 (2%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            MTIP  Q  M P+L  L D     +  +I+ M D F LSDDER ++L SGR   +  RVH
Sbjct  19   MTIPTYQECMLPMLKVLKDNSNIKSTRLISLMGDWFHLSDDEREELLSSGRTTILRTRVH  78

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+  ++ QAGL++ P RG+V +T+ G QVL+ +P  +D   L++FP +I F ER+K +  
Sbjct  79   WAKVYLKQAGLVEYPKRGYVAITEKGIQVLQKNPSNIDTNYLKKFPDFIRFIERSKTESQ  138

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
              + ++         SP++++       +     E+L+   + SP  FE LV++++ ++G
Sbjct  139  QVSNSEYSEN----YSPDEVLTRTFERMKNQTCEELLEVIKSSSPQFFEKLVVQVIVSLG  194

Query  181  YGRA--GAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQ-TIGRPKIHEFAGAL  237
            YG +   A +    SGD G+DG+I +D LGL+ IY+QAK    D+  +GRP I +F GAL
Sbjct  195  YGGSLQEAGQAIGKSGDGGVDGVIKEDRLGLELIYLQAKLKKDDKYNVGRPDIQKFYGAL  254

Query  238  LGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELLR  297
             GKQ  +G++ITT+ FS  ARE  + I+ +I L++G  L EL+  Y +G+    T E+  
Sbjct  255  QGKQAKKGIFITTTDFSNEAREYLKVIDKKIILLNGKELIELMWEYNIGLNVSATYEVKD  314

Query  298  LDEDFF  303
            LD DFF
Sbjct  315  LDLDFF  320


>gi|339442916|ref|YP_004708921.1| hypothetical protein CXIVA_18520 [Clostridium sp. SY8519]
 gi|338902317|dbj|BAK47819.1| hypothetical protein CXIVA_18520 [Clostridium sp. SY8519]
Length=306

 Score =  225 bits (574),  Expect = 5e-57, Method: Compositional matrix adjust.
 Identities = 117/308 (38%), Positives = 184/308 (60%), Gaps = 11/308 (3%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M +P         L    DG+  +AK+V   ++ E  +SD +R +MLPSG+Q T  +RV 
Sbjct  1    MAVPKFFEFFEGFLRATQDGELHTAKEVREIIAKEMNISDADRLEMLPSGKQTTFANRVA  60

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAFRERTKAKQP  120
            W+ T++ +AGL++ PTRG  ++T+ G+  L +  E++D+  L     +  F +   +K  
Sbjct  61   WARTYLDKAGLIETPTRGKYRITEAGKNALTS-GEKIDLKYLERSDKFKEFHKAATSKSA  119

Query  121  VDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEAMG  180
             D        D+   SP + +DAA  +  A +  +++ + + L+P+ FE LV++LL  MG
Sbjct  120  EDTDQDNTESDE---SPMETLDAAFQQVNATLASQLMDEVMKLTPSEFERLVVKLLLKMG  176

Query  181  YG----RAGAVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGA  236
            YG     AG V  T  S D GIDGII +D LG   IY+QAK++AVDQT+G+P+I +F GA
Sbjct  177  YGSGIEEAGMV--TQPSNDGGIDGIIKEDQLGFSHIYIQAKQWAVDQTVGKPEIQKFVGA  234

Query  237  LLGKQGDRGVYITTSSFSRGAREEAER-INARIELIDGARLAELLVRYRVGVQAVQTVEL  295
            L G+Q  +G++ITT+ FS GA + A+  + A++ L+DG  L +L++++ VGV      E+
Sbjct  235  LQGQQAQKGLFITTAKFSSGALQFADNLLGAKVVLVDGTALTKLMIKHNVGVSVEHIYEV  294

Query  296  LRLDEDFF  303
             RLD DFF
Sbjct  295  KRLDSDFF  302


>gi|154245042|ref|YP_001416000.1| restriction endonuclease [Xanthobacter autotrophicus Py2]
 gi|154159127|gb|ABS66343.1| restriction endonuclease [Xanthobacter autotrophicus Py2]
Length=310

 Score =  225 bits (574),  Expect = 7e-57, Method: Compositional matrix adjust.
 Identities = 125/307 (41%), Positives = 197/307 (65%), Gaps = 5/307 (1%)

Query  1    MTIPDAQTLMRPILAYLADGQAKSAKDVIAAMSDEFGLSDDERAQMLPSGRQRTMYDRVH  60
            M IPD QTLM P+L   A+G+ +   ++   + ++FGLS+ ER  +LPSGRQ+ +++R+H
Sbjct  1    MPIPDYQTLMLPLLKIAAEGETR-IPELEERICNDFGLSEAEREALLPSGRQKVIHNRLH  59

Query  61   WSLTHMSQAGLLDRPTRGHVQVTDTGRQVLKAHPERVDMAVLREFPSYIAF--RERTKAK  118
            WS  ++++AGL+D P+RG    +  GR++L  +P R+D+ +L  +P++  F    R  A 
Sbjct  60   WSKFYLTRAGLMDVPSRGRFVASPAGRELLARNPPRIDIPLLETYPAFREFYRNAREGAG  119

Query  119  QPVDATAKRPSGDDVQVSPEDLIDAALAENRAAVEGEILKKALTLSPTGFEDLVIRLLEA  178
            +        P      V+PE+ ++AA A  +AA+  ++L + L   P  FE +++ LL A
Sbjct  120  ENEVGAEVAPPPVPATVTPEEQVEAAYAALQAALRQDLLARILQNPPAFFERVIVTLLVA  179

Query  179  MGYGRAG--AVERTSASGDAGIDGIISQDPLGLDRIYVQAKRYAVDQTIGRPKIHEFAGA  236
            MGYG +   A ++   SGD G+DG+I++D LGLDR+YVQAKRYA    +GRP++  F G+
Sbjct  180  MGYGGSHRDAAQQLGRSGDGGVDGVINEDRLGLDRVYVQAKRYAPGNAVGRPEVQGFVGS  239

Query  237  LLGKQGDRGVYITTSSFSRGAREEAERINARIELIDGARLAELLVRYRVGVQAVQTVELL  296
            L+G    +GV++TTS+FS  AR+    +  R+ LIDG +LA+L++ + VGV+  + VE  
Sbjct  240  LVGLGATKGVFVTTSAFSTQARDFVRHLTQRVILIDGQQLADLMIEHNVGVRLTRAVEFK  299

Query  297  RLDEDFF  303
            RLDEDFF
Sbjct  300  RLDEDFF  306



Lambda     K      H
   0.318    0.135    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 518193349062


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40