BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2573 Length=246 Score E Sequences producing significant alignments: (Bits) Value gi|20141798|sp|Q50648.2|PANE_MYCTU RecName: Full=Putative 2-dehy... 485 2e-135 gi|15842111|ref|NP_337148.1| 2-dehydropantoate 2-reductase [Myco... 484 6e-135 gi|121638458|ref|YP_978682.1| 2-dehydropantoate 2-reductase [Myc... 484 6e-135 gi|308377057|ref|ZP_07441000.2| hypothetical protein TMHG_01767 ... 483 8e-135 gi|289448222|ref|ZP_06437966.1| 2-dehydropantoate 2-reductase [M... 483 1e-134 gi|254366774|ref|ZP_04982817.1| conserved hypothetical protein [... 481 4e-134 gi|289754691|ref|ZP_06514069.1| oxidoreductase [Mycobacterium tu... 481 5e-134 gi|289751196|ref|ZP_06510574.1| conserved hypothetical protein [... 481 5e-134 gi|183982170|ref|YP_001850461.1| ketopantoate reductase, ApbA_1 ... 395 3e-108 gi|240173263|ref|ZP_04751921.1| 2-dehydropantoate 2-reductase [M... 393 1e-107 gi|118617363|ref|YP_905695.1| 2-dehydropantoate 2-reductase [Myc... 392 2e-107 gi|254823292|ref|ZP_05228293.1| 2-dehydropantoate 2-reductase [M... 385 4e-105 gi|48928128|gb|AAT47742.1| hypothetical protein MA1062ptb [Mycob... 376 1e-102 gi|118466556|ref|YP_882630.1| 2-dehydropantoate 2-reductase [Myc... 376 2e-102 gi|254775891|ref|ZP_05217407.1| 2-dehydropantoate 2-reductase [M... 375 3e-102 gi|296170801|ref|ZP_06852372.1| 2-dehydropantoate 2-reductase [M... 374 6e-102 gi|336461510|gb|EGO40378.1| 2-dehydropantoate 2-reductase [Mycob... 372 2e-101 gi|41395511|gb|AAS03379.1| hypothetical protein MAP_1062c [Mycob... 372 3e-101 gi|161611207|ref|NP_959996.2| 2-dehydropantoate 2-reductase [Myc... 372 4e-101 gi|342858611|ref|ZP_08715266.1| 2-dehydropantoate 2-reductase [M... 368 5e-100 gi|119868390|ref|YP_938342.1| 2-dehydropantoate 2-reductase [Myc... 315 5e-84 gi|108799274|ref|YP_639471.1| 2-dehydropantoate 2-reductase [Myc... 314 7e-84 gi|339295451|gb|AEJ47562.1| 2-dehydropantoate 2-reductase [Mycob... 293 2e-77 gi|148271549|ref|YP_001221110.1| 2-dehydropantoate 2-reductase [... 278 6e-73 gi|221199031|ref|ZP_03572076.1| 2-dehydropantoate 2-reductase [B... 275 3e-72 gi|170693852|ref|ZP_02885009.1| 2-dehydropantoate 2-reductase [B... 275 6e-72 gi|317405083|gb|EFV85429.1| 2-dehydropantoate 2-reductase [Achro... 270 2e-70 gi|323524925|ref|YP_004227078.1| 2-dehydropantoate 2-reductase [... 266 3e-69 gi|339762711|gb|AEJ98931.1| 2-dehydropantoate 2-reductase [Klebs... 265 5e-69 gi|293607460|ref|ZP_06689798.1| ketopantoate reductase family ox... 265 5e-69 gi|206575388|ref|YP_002235557.1| putative 2-dehydropantoate 2-re... 265 6e-69 gi|221212150|ref|ZP_03585128.1| 2-dehydropantoate 2-reductase [B... 263 2e-68 gi|317049124|ref|YP_004116772.1| 2-dehydropantoate 2-reductase [... 260 1e-67 gi|152970009|ref|YP_001335118.1| 2-dehydropantoate 2-reductase [... 259 2e-67 gi|339761701|gb|AEJ97921.1| 2-dehydropantoate 2-reductase [Klebs... 259 2e-67 gi|290509798|ref|ZP_06549169.1| 2-dehydropantoate 2-reductase [K... 259 3e-67 gi|289570744|ref|ZP_06450971.1| conserved hypothetical protein [... 259 3e-67 gi|238894476|ref|YP_002919210.1| 2-dehydropantoate 2-reductase [... 258 6e-67 gi|161523104|ref|YP_001586033.1| 2-dehydropantoate 2-reductase [... 257 1e-66 gi|239817272|ref|YP_002946182.1| 2-dehydropantoate 2-reductase [... 257 1e-66 gi|242238390|ref|YP_002986571.1| 2-dehydropantoate 2-reductase [... 257 1e-66 gi|288935771|ref|YP_003439830.1| 2-dehydropantoate 2-reductase [... 257 1e-66 gi|330015003|ref|ZP_08308036.1| 2-dehydropantoate 2-reductase [K... 256 1e-66 gi|333928084|ref|YP_004501663.1| 2-dehydropantoate 2-reductase [... 256 2e-66 gi|307729664|ref|YP_003906888.1| 2-dehydropantoate 2-reductase [... 256 2e-66 gi|206578066|ref|YP_002238841.1| 2-dehydropantoate 2-reductase [... 256 2e-66 gi|296103486|ref|YP_003613632.1| 2-dehydropantoate 2-reductase [... 256 2e-66 gi|172065408|ref|YP_001816120.1| 2-dehydropantoate 2-reductase [... 255 3e-66 gi|293395438|ref|ZP_06639722.1| ketopantoate reductase family ox... 255 5e-66 gi|187919858|ref|YP_001888889.1| 2-dehydropantoate 2-reductase [... 254 6e-66 >gi|20141798|sp|Q50648.2|PANE_MYCTU RecName: Full=Putative 2-dehydropantoate 2-reductase; AltName: Full=Ketopantoate reductase; Short=KPA reductase; Short=KPR Length=295 Score = 485 bits (1248), Expect = 2e-135, Method: Compositional matrix adjust. Identities = 246/246 (100%), Positives = 246/246 (100%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ Sbjct 50 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 109 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD Sbjct 110 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 169 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV Sbjct 170 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 229 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA Sbjct 230 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 289 Query 241 ASDGPG 246 ASDGPG Sbjct 290 ASDGPG 295 >gi|15842111|ref|NP_337148.1| 2-dehydropantoate 2-reductase [Mycobacterium tuberculosis CDC1551] gi|148823768|ref|YP_001288522.1| 2-dehydropantoate 2-reductase [Mycobacterium tuberculosis F11] gi|161352464|ref|NP_217089.2| 2-dehydropantoate 2-reductase [Mycobacterium tuberculosis H37Rv] 43 more sequence titles Length=275 Score = 484 bits (1245), Expect = 6e-135, Method: Compositional matrix adjust. Identities = 246/246 (100%), Positives = 246/246 (100%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ Sbjct 30 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 89 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD Sbjct 90 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 149 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV Sbjct 150 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 209 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA Sbjct 210 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 269 Query 241 ASDGPG 246 ASDGPG Sbjct 270 ASDGPG 275 >gi|121638458|ref|YP_978682.1| 2-dehydropantoate 2-reductase [Mycobacterium bovis BCG str. Pasteur 1173P2] gi|148662412|ref|YP_001283935.1| 2-dehydropantoate 2-reductase [Mycobacterium tuberculosis H37Ra] gi|224990952|ref|YP_002645639.1| 2-dehydropantoate 2-reductase [Mycobacterium bovis BCG str. Tokyo 172] 21 more sequence titles Length=246 Score = 484 bits (1245), Expect = 6e-135, Method: Compositional matrix adjust. Identities = 245/246 (99%), Positives = 246/246 (100%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 +VPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ Sbjct 1 MVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD Sbjct 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV Sbjct 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA Sbjct 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 Query 241 ASDGPG 246 ASDGPG Sbjct 241 ASDGPG 246 >gi|308377057|ref|ZP_07441000.2| hypothetical protein TMHG_01767 [Mycobacterium tuberculosis SUMu008] gi|308349084|gb|EFP37935.1| hypothetical protein TMHG_01767 [Mycobacterium tuberculosis SUMu008] Length=267 Score = 483 bits (1244), Expect = 8e-135, Method: Compositional matrix adjust. Identities = 246/246 (100%), Positives = 246/246 (100%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ Sbjct 22 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 81 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD Sbjct 82 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 141 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV Sbjct 142 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 201 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA Sbjct 202 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 261 Query 241 ASDGPG 246 ASDGPG Sbjct 262 ASDGPG 267 >gi|289448222|ref|ZP_06437966.1| 2-dehydropantoate 2-reductase [Mycobacterium tuberculosis CPHL_A] gi|289421180|gb|EFD18381.1| 2-dehydropantoate 2-reductase [Mycobacterium tuberculosis CPHL_A] Length=246 Score = 483 bits (1243), Expect = 1e-134, Method: Compositional matrix adjust. Identities = 244/246 (99%), Positives = 245/246 (99%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 +VPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ Sbjct 1 MVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSSAVVP IVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD Sbjct 61 PHCPSSAVVPTIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV Sbjct 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA Sbjct 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 Query 241 ASDGPG 246 ASDGPG Sbjct 241 ASDGPG 246 >gi|254366774|ref|ZP_04982817.1| conserved hypothetical protein [Mycobacterium tuberculosis str. Haarlem] gi|134152285|gb|EBA44330.1| conserved hypothetical protein [Mycobacterium tuberculosis str. Haarlem] Length=275 Score = 481 bits (1238), Expect = 4e-134, Method: Compositional matrix adjust. Identities = 245/246 (99%), Positives = 245/246 (99%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ Sbjct 30 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 89 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTG AAEQFAGLLRGAGATVDCDPD Sbjct 90 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGSAAEQFAGLLRGAGATVDCDPD 149 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV Sbjct 150 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 209 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA Sbjct 210 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 269 Query 241 ASDGPG 246 ASDGPG Sbjct 270 ASDGPG 275 >gi|289754691|ref|ZP_06514069.1| oxidoreductase [Mycobacterium tuberculosis EAS054] gi|289695278|gb|EFD62707.1| oxidoreductase [Mycobacterium tuberculosis EAS054] Length=246 Score = 481 bits (1237), Expect = 5e-134, Method: Compositional matrix adjust. Identities = 244/246 (99%), Positives = 245/246 (99%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 +VPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ Sbjct 1 MVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSSAVVPAIVWCSAETQPQ WVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD Sbjct 61 PHCPSSAVVPAIVWCSAETQPQRWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV Sbjct 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA Sbjct 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 Query 241 ASDGPG 246 ASDGPG Sbjct 241 ASDGPG 246 >gi|289751196|ref|ZP_06510574.1| conserved hypothetical protein [Mycobacterium tuberculosis T92] gi|289691783|gb|EFD59212.1| conserved hypothetical protein [Mycobacterium tuberculosis T92] Length=246 Score = 481 bits (1237), Expect = 5e-134, Method: Compositional matrix adjust. Identities = 244/246 (99%), Positives = 245/246 (99%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 +VPGPVHTSPREVAGPVDVLILAVKATQNDAA PWLTRLCDERTVVAVLQNGVEQVEQVQ Sbjct 1 MVPGPVHTSPREVAGPVDVLILAVKATQNDAAPPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD Sbjct 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV Sbjct 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA Sbjct 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 Query 241 ASDGPG 246 ASDGPG Sbjct 241 ASDGPG 246 >gi|183982170|ref|YP_001850461.1| ketopantoate reductase, ApbA_1 [Mycobacterium marinum M] gi|183175496|gb|ACC40606.1| ketopantoate reductase, ApbA_1 [Mycobacterium marinum M] Length=268 Score = 395 bits (1015), Expect = 3e-108, Method: Compositional matrix adjust. Identities = 197/246 (81%), Positives = 215/246 (88%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P++++GPVDVLILAVKATQ AAR WL RLC E TVVAVLQNGVEQVEQV+ Sbjct 23 VVPGPVHTDPQQLSGPVDVLILAVKATQTGAAREWLARLCGEHTVVAVLQNGVEQVEQVR 82 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSS++V VW +AETQP GWVRLRG+AALV+PTG AAE AGLLR AG VDCDPD Sbjct 83 PHCPSSSIVAGSVWFAAETQPGGWVRLRGDAALVLPTGAAAETLAGLLRAAGCRVDCDPD 142 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT WRKL++NALAG M LSGRRS MFRRDD+A LSR YVAECLAVARAEGARLDDDV+ Sbjct 143 FTTVIWRKLVLNALAGLMALSGRRSGMFRRDDIAELSRHYVAECLAVARAEGARLDDDVI 202 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+V L SAP+DMGTS+LADR AHR LEWDLRNGVI+RKARAHGLATPIS VLVPLLAA Sbjct 203 DEMVDLFASAPEDMGTSILADREAHRRLEWDLRNGVIIRKARAHGLATPISQVLVPLLAA 262 Query 241 ASDGPG 246 ASDGPG Sbjct 263 ASDGPG 268 >gi|240173263|ref|ZP_04751921.1| 2-dehydropantoate 2-reductase [Mycobacterium kansasii ATCC 12478] Length=289 Score = 393 bits (1010), Expect = 1e-107, Method: Compositional matrix adjust. Identities = 205/246 (84%), Positives = 218/246 (89%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P +VAGPV+V+ILAVKATQND+ R WL RLC E TVVAVLQNGVEQVEQVQ Sbjct 44 VVPGPVHTDPDDVAGPVEVVILAVKATQNDSTRGWLARLCGEHTVVAVLQNGVEQVEQVQ 103 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSS VVP VW SAETQP GWVRLRGEAALV+PTG AAE A LLRGAGA VDCDPD Sbjct 104 PHCPSSTVVPGSVWFSAETQPDGWVRLRGEAALVLPTGAAAEAVAELLRGAGARVDCDPD 163 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT WRKL++NALAG M LSGRRS MFRRDDVAALSRRYVAECLAVARAEGARL DD V Sbjct 164 FTTVLWRKLVLNALAGLMALSGRRSGMFRRDDVAALSRRYVAECLAVARAEGARLGDDAV 223 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 +E+V L RSAP+DMGTS+LADR AHR LEWDLRNGVI+RKARAHGLATPISDV+VPLLAA Sbjct 224 EEMVNLFRSAPEDMGTSILADREAHRRLEWDLRNGVIIRKARAHGLATPISDVVVPLLAA 283 Query 241 ASDGPG 246 ASDGPG Sbjct 284 ASDGPG 289 >gi|118617363|ref|YP_905695.1| 2-dehydropantoate 2-reductase [Mycobacterium ulcerans Agy99] gi|118569473|gb|ABL04224.1| ketopantoate reductase, ApbA_1 [Mycobacterium ulcerans Agy99] Length=246 Score = 392 bits (1007), Expect = 2e-107, Method: Compositional matrix adjust. Identities = 195/246 (80%), Positives = 213/246 (87%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 +VPGPVHT P++++GPVDVLI AVKATQ AAR WL RLC E TVVAVLQNGVEQVEQVQ Sbjct 1 MVPGPVHTDPQQLSGPVDVLIFAVKATQTGAAREWLARLCGEHTVVAVLQNGVEQVEQVQ 60 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSS++V VW +AETQP GWVRLRG+AALV+PTG AAE AGLLR AG VDCD D Sbjct 61 PHCPSSSIVAGSVWFAAETQPGGWVRLRGDAALVLPTGAAAETLAGLLRAAGCRVDCDLD 120 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT WRKL++NALAG M LSGRRS MFRRDD+A LSR YVAECLAVARAEGARLDDDV+ Sbjct 121 FTTVIWRKLVLNALAGLMALSGRRSGMFRRDDIAELSRHYVAECLAVARAEGARLDDDVI 180 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+V L SAP+DMGTS+LADR AHR LEWDLRNGVI+RKARAHGLATPIS VLVPLLAA Sbjct 181 DEMVDLFASAPEDMGTSILADREAHRRLEWDLRNGVIIRKARAHGLATPISQVLVPLLAA 240 Query 241 ASDGPG 246 ASDGPG Sbjct 241 ASDGPG 246 >gi|254823292|ref|ZP_05228293.1| 2-dehydropantoate 2-reductase [Mycobacterium intracellulare ATCC 13950] Length=266 Score = 385 bits (988), Expect = 4e-105, Method: Compositional matrix adjust. Identities = 191/246 (78%), Positives = 209/246 (85%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P EV+GPVDV++LAVKA QND A WL RLCD T+V VLQNGVEQVEQVQ Sbjct 21 VVPGPVHTDPGEVSGPVDVVLLAVKAAQNDQAAGWLARLCDVHTIVVVLQNGVEQVEQVQ 80 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCP S V+P IVW SAETQP GWVRLRGEAALV+P+GP+AE A LLRGAG VDCDPD Sbjct 81 PHCPRSPVIPGIVWYSAETQPDGWVRLRGEAALVLPSGPSAETVAELLRGAGCRVDCDPD 140 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 TA WRKLL NALAGFM LS RRS MFRRDDVAALSRRY+AECLAVARAEGARL D + Sbjct 141 IITAGWRKLLTNALAGFMALSRRRSGMFRRDDVAALSRRYLAECLAVARAEGARLPDGIA 200 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+ L R+AP+DMGTS+L D HRP+EWD+RNGVI+RKARAHGLATPISDV+VPLLAA Sbjct 201 DELTDLFRNAPEDMGTSILTDAENHRPMEWDVRNGVIIRKARAHGLATPISDVVVPLLAA 260 Query 241 ASDGPG 246 ASDGPG Sbjct 261 ASDGPG 266 >gi|48928128|gb|AAT47742.1| hypothetical protein MA1062ptb [Mycobacterium avium] Length=255 Score = 376 bits (966), Expect = 1e-102, Method: Compositional matrix adjust. Identities = 191/246 (78%), Positives = 206/246 (84%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P V+GPVDV++LAVKATQN A WL RLC E TVV VLQNGVEQVEQV+ Sbjct 10 VVPGPVHTDPGRVSGPVDVVLLAVKATQNAGAAGWLARLCGEHTVVVVLQNGVEQVEQVR 69 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P CP S V+P IVW SA TQPQGWVRLR E ALV+P+GP+A+ A LLR AG VDCDPD Sbjct 70 PLCPDSPVIPGIVWYSATTQPQGWVRLRTEPALVLPSGPSAQAVAALLRDAGCRVDCDPD 129 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 TAAWRKLL NALAGFM LS RRS MFRRDDVAALSRRYVAECLAVARAEGARL DDVV Sbjct 130 IITAAWRKLLTNALAGFMALSRRRSGMFRRDDVAALSRRYVAECLAVARAEGARLSDDVV 189 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+V L R AP+DMGTS+L+D AHRP+EWD+RNGVI RK RAHGL TPISDVLVPLLAA Sbjct 190 DELVELFRRAPEDMGTSILSDAEAHRPMEWDVRNGVIARKGRAHGLPTPISDVLVPLLAA 249 Query 241 ASDGPG 246 ASDGPG Sbjct 250 ASDGPG 255 >gi|118466556|ref|YP_882630.1| 2-dehydropantoate 2-reductase [Mycobacterium avium 104] gi|118167843|gb|ABK68740.1| 2-dehydropantoate 2-reductase [Mycobacterium avium 104] Length=267 Score = 376 bits (965), Expect = 2e-102, Method: Compositional matrix adjust. Identities = 191/246 (78%), Positives = 206/246 (84%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P V+GPVDV++LAVKATQN A WL RLC E TVV VLQNGVEQVEQV+ Sbjct 22 VVPGPVHTDPGRVSGPVDVVLLAVKATQNAGAAGWLARLCGEHTVVVVLQNGVEQVEQVR 81 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P CP S V+P IVW SA TQPQGWVRLR E ALV+P+GP+A+ A LLR AG VDCDPD Sbjct 82 PLCPDSPVIPGIVWYSATTQPQGWVRLRTEPALVLPSGPSAQAVAALLRDAGCRVDCDPD 141 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 TAAWRKLL NALAGFM LS RRS MFRRDDVAALSRRYVAECLAVARAEGARL DDVV Sbjct 142 IITAAWRKLLTNALAGFMALSRRRSGMFRRDDVAALSRRYVAECLAVARAEGARLSDDVV 201 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+V L R AP+DMGTS+L+D AHRP+EWD+RNGVI RK RAHGL TPISDVLVPLLAA Sbjct 202 DELVELFRRAPEDMGTSILSDAEAHRPMEWDVRNGVIARKGRAHGLPTPISDVLVPLLAA 261 Query 241 ASDGPG 246 ASDGPG Sbjct 262 ASDGPG 267 >gi|254775891|ref|ZP_05217407.1| 2-dehydropantoate 2-reductase [Mycobacterium avium subsp. avium ATCC 25291] Length=268 Score = 375 bits (964), Expect = 3e-102, Method: Compositional matrix adjust. Identities = 191/246 (78%), Positives = 206/246 (84%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P V+GPVDV++LAVKATQN A WL RLC E TVV VLQNGVEQVEQV+ Sbjct 23 VVPGPVHTDPGRVSGPVDVVLLAVKATQNAGAAGWLARLCGEHTVVVVLQNGVEQVEQVR 82 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P CP S V+P IVW SA TQPQGWVRLR E ALV+P+GP+A+ A LLR AG VDCDPD Sbjct 83 PLCPVSPVIPGIVWYSATTQPQGWVRLRTEPALVLPSGPSAQAVAALLRDAGCRVDCDPD 142 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 TAAWRKLL NALAGFM LS RRS MFRRDDVAALSRRYVAECLAVARAEGARL DDVV Sbjct 143 IITAAWRKLLTNALAGFMALSRRRSGMFRRDDVAALSRRYVAECLAVARAEGARLSDDVV 202 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+V L R AP+DMGTS+L+D AHRP+EWD+RNGVI RK RAHGL TPISDVLVPLLAA Sbjct 203 DELVELFRRAPEDMGTSILSDAEAHRPMEWDVRNGVIARKGRAHGLPTPISDVLVPLLAA 262 Query 241 ASDGPG 246 ASDGPG Sbjct 263 ASDGPG 268 >gi|296170801|ref|ZP_06852372.1| 2-dehydropantoate 2-reductase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894537|gb|EFG74275.1| 2-dehydropantoate 2-reductase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=268 Score = 374 bits (961), Expect = 6e-102, Method: Compositional matrix adjust. Identities = 185/246 (76%), Positives = 208/246 (85%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV T P ++ GP DV++LAVKATQN+AA WL RLC T+V VLQNGVEQVEQVQ Sbjct 23 VVPGPVRTDPDQITGPADVVVLAVKATQNEAAAGWLARLCAAHTIVVVLQNGVEQVEQVQ 82 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCPSS V+P IVW SAETQP+GWVRLR + ALV+P+GP+AE A LLRGAG VDCDPD Sbjct 83 PHCPSSPVLPGIVWYSAETQPEGWVRLRTDPALVLPSGPSAETIAELLRGAGCRVDCDPD 142 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F TAAWRKLL NALAGFM L+GRRS MFRRDDVA LSRRYVAECLAVARAEGARL D +V Sbjct 143 FVTAAWRKLLTNALAGFMALAGRRSGMFRRDDVADLSRRYVAECLAVARAEGARLPDAIV 202 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+ + R P+DMGTS+LADR HR +EWD+RNGVI+RKARAHGL TP+SDV+VPLLAA Sbjct 203 DELGDMFRHVPEDMGTSILADRENHRRMEWDIRNGVIIRKARAHGLPTPVSDVVVPLLAA 262 Query 241 ASDGPG 246 ASDGPG Sbjct 263 ASDGPG 268 >gi|336461510|gb|EGO40378.1| 2-dehydropantoate 2-reductase [Mycobacterium avium subsp. paratuberculosis S397] Length=268 Score = 372 bits (956), Expect = 2e-101, Method: Compositional matrix adjust. Identities = 190/246 (78%), Positives = 205/246 (84%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P V+GPVDV++LAVKATQN A WL RLC E TVV VLQNGVEQVEQV+ Sbjct 23 VVPGPVHTDPGRVSGPVDVVLLAVKATQNAGAAGWLARLCGEHTVVVVLQNGVEQVEQVR 82 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P CP S V+P IVW SA TQPQGWVRLR E ALV+P+GP+A+ A LLR AG VDCDPD Sbjct 83 PLCPVSPVIPGIVWYSATTQPQGWVRLRTEPALVLPSGPSAQAVAALLRDAGCRVDCDPD 142 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 TAAW KLL NALAGFM LS RRS MFRRDDVAALSRRYVAECLAVARAEGARL DDVV Sbjct 143 IITAAWHKLLTNALAGFMALSRRRSGMFRRDDVAALSRRYVAECLAVARAEGARLSDDVV 202 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+V L R AP+DMGTS+L+D AHRP+EWD+RNGVI RK RAHGL TPISDVLVPLLAA Sbjct 203 DELVDLFRRAPEDMGTSILSDAEAHRPMEWDVRNGVIARKGRAHGLPTPISDVLVPLLAA 262 Query 241 ASDGPG 246 ASDGPG Sbjct 263 ASDGPG 268 >gi|41395511|gb|AAS03379.1| hypothetical protein MAP_1062c [Mycobacterium avium subsp. paratuberculosis K-10] Length=255 Score = 372 bits (955), Expect = 3e-101, Method: Compositional matrix adjust. Identities = 190/246 (78%), Positives = 204/246 (83%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P V+GPVDV++LAVKATQN A WL RLC E TVV VLQNGVEQVEQV+ Sbjct 10 VVPGPVHTDPGRVSGPVDVVLLAVKATQNAGAAGWLARLCGEHTVVVVLQNGVEQVEQVR 69 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P CP S V P IVW SA TQPQGWVRLR E ALV+P+GP+A+ A LLR AG VDCDPD Sbjct 70 PLCPVSPVTPGIVWYSATTQPQGWVRLRTEPALVLPSGPSAQAVAALLRDAGCRVDCDPD 129 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 TAAW KLL NALAGFM LS RRS MFRRDDVAALSRRYVAECLAVARAEGARL DDVV Sbjct 130 IITAAWHKLLTNALAGFMALSRRRSGMFRRDDVAALSRRYVAECLAVARAEGARLSDDVV 189 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+V L R AP+DMGTS+L+D AHRP+EWD+RNGVI RK RAHGL TPISDVLVPLLAA Sbjct 190 DELVDLFRRAPEDMGTSILSDAEAHRPMEWDVRNGVIARKGRAHGLPTPISDVLVPLLAA 249 Query 241 ASDGPG 246 ASDGPG Sbjct 250 ASDGPG 255 >gi|161611207|ref|NP_959996.2| 2-dehydropantoate 2-reductase [Mycobacterium avium subsp. paratuberculosis K-10] Length=268 Score = 372 bits (954), Expect = 4e-101, Method: Compositional matrix adjust. Identities = 190/246 (78%), Positives = 204/246 (83%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P V+GPVDV++LAVKATQN A WL RLC E TVV VLQNGVEQVEQV+ Sbjct 23 VVPGPVHTDPGRVSGPVDVVLLAVKATQNAGAAGWLARLCGEHTVVVVLQNGVEQVEQVR 82 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P CP S V P IVW SA TQPQGWVRLR E ALV+P+GP+A+ A LLR AG VDCDPD Sbjct 83 PLCPVSPVTPGIVWYSATTQPQGWVRLRTEPALVLPSGPSAQAVAALLRDAGCRVDCDPD 142 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 TAAW KLL NALAGFM LS RRS MFRRDDVAALSRRYVAECLAVARAEGARL DDVV Sbjct 143 IITAAWHKLLTNALAGFMALSRRRSGMFRRDDVAALSRRYVAECLAVARAEGARLSDDVV 202 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+V L R AP+DMGTS+L+D AHRP+EWD+RNGVI RK RAHGL TPISDVLVPLLAA Sbjct 203 DELVDLFRRAPEDMGTSILSDAEAHRPMEWDVRNGVIARKGRAHGLPTPISDVLVPLLAA 262 Query 241 ASDGPG 246 ASDGPG Sbjct 263 ASDGPG 268 >gi|342858611|ref|ZP_08715266.1| 2-dehydropantoate 2-reductase [Mycobacterium colombiense CECT 3035] gi|342134315|gb|EGT87495.1| 2-dehydropantoate 2-reductase [Mycobacterium colombiense CECT 3035] Length=267 Score = 368 bits (944), Expect = 5e-100, Method: Compositional matrix adjust. Identities = 184/246 (75%), Positives = 205/246 (84%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV T P EV GPVDV++LAVKATQNDAA WL RLCD T+V VLQNGVEQVEQVQ Sbjct 22 VVPGPVRTDPAEVTGPVDVVLLAVKATQNDAAAGWLARLCDVHTIVVVLQNGVEQVEQVQ 81 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHCP S V+P IVW SA+TQP+GWVRLR E ALV+P+GP+ + A LLRGAG V+CDPD Sbjct 82 PHCPLSPVIPGIVWYSAQTQPEGWVRLRTEPALVLPSGPSGQAVAELLRGAGCRVECDPD 141 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 TAAW KLL NALAGFM L+ RRS MFRRDDVAALSRRYVAECLAVARAEGARL D V Sbjct 142 IITAAWHKLLTNALAGFMALARRRSGMFRRDDVAALSRRYVAECLAVARAEGARLADGVA 201 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DE+V + R+A +D+GTS+L D RP+EWD+RNGVIVRK RAHGLATPISDV+VPLLAA Sbjct 202 DELVGMFRNAAEDLGTSILTDAEQQRPMEWDIRNGVIVRKGRAHGLATPISDVIVPLLAA 261 Query 241 ASDGPG 246 ASDGPG Sbjct 262 ASDGPG 267 >gi|119868390|ref|YP_938342.1| 2-dehydropantoate 2-reductase [Mycobacterium sp. KMS] gi|119694479|gb|ABL91552.1| ketopantoate reductase [Mycobacterium sp. KMS] Length=295 Score = 315 bits (806), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 160/246 (66%), Positives = 190/246 (78%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 V+PGPVHT P +V GPVDV++LAVK TQN+AA PWL+RLC RTVV LQNGVEQVE+V Sbjct 50 VIPGPVHTDPADVDGPVDVVLLAVKDTQNEAAAPWLSRLCGSRTVVCALQNGVEQVERVG 109 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 CP + VVPA VW SAET G VRLR +A +V+P AA A L +V CDPD Sbjct 110 RFCPDATVVPAAVWMSAETSGPGQVRLRTDARVVLPATEAAAMLADTLATPHLSVACDPD 169 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F +AAWRKLLVNA+ G MVL+GRRS MFRRDD+AAL RRY+AECLAVARA+GA L D+VV Sbjct 170 FASAAWRKLLVNAVVGLMVLTGRRSGMFRRDDIAALGRRYLAECLAVARADGAALGDEVV 229 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DEV+ ++ + P D+ TSML DR A R LEWD+RNGVI RK A+G+ATPISD++VPLLAA Sbjct 230 DEVIGMLAAGPPDITTSMLTDREAGRALEWDIRNGVIARKGAAYGIATPISDIVVPLLAA 289 Query 241 ASDGPG 246 A +GPG Sbjct 290 AGEGPG 295 >gi|108799274|ref|YP_639471.1| 2-dehydropantoate 2-reductase [Mycobacterium sp. MCS] gi|108769693|gb|ABG08415.1| ketopantoate reductase [Mycobacterium sp. MCS] Length=319 Score = 314 bits (805), Expect = 7e-84, Method: Compositional matrix adjust. Identities = 160/246 (66%), Positives = 190/246 (78%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 V+PGPVHT P +V GPVDV++LAVK TQN+AA PWL+RLC RTVV LQNGVEQVE+V Sbjct 74 VIPGPVHTDPADVDGPVDVVLLAVKDTQNEAAAPWLSRLCGSRTVVCALQNGVEQVERVG 133 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 CP + VVPA VW SAET G VRLR +A +V+P AA A L +V CDPD Sbjct 134 RFCPDATVVPAAVWMSAETSGPGQVRLRTDARVVLPATEAAAMLADTLATPHLSVACDPD 193 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F +AAWRKLLVNA+ G MVL+GRRS MFRRDD+AAL RRY+AECLAVARA+GA L D+VV Sbjct 194 FASAAWRKLLVNAVVGLMVLTGRRSGMFRRDDIAALGRRYLAECLAVARADGAALGDEVV 253 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 DEV+ ++ + P D+ TSML DR A R LEWD+RNGVI RK A+G+ATPISD++VPLLAA Sbjct 254 DEVIGMLAAGPPDITTSMLTDREAGRALEWDIRNGVIARKGAAYGIATPISDIVVPLLAA 313 Query 241 ASDGPG 246 A +GPG Sbjct 314 AGEGPG 319 >gi|339295451|gb|AEJ47562.1| 2-dehydropantoate 2-reductase [Mycobacterium tuberculosis CCDC5079] Length=158 Score = 293 bits (750), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 150/152 (99%), Positives = 150/152 (99%), Gaps = 0/152 (0%) Query 95 VPTGPAAEQFAGLLRGAGATVDCDPDFTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVA 154 P GPAAEQFAGLLRGAGATVDCDPDFTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVA Sbjct 7 FPPGPAAEQFAGLLRGAGATVDCDPDFTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVA 66 Query 155 ALSRRYVAECLAVARAEGARLDDDVVDEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRN 214 ALSRRYVAECLAVARAEGARLDDDVVDEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRN Sbjct 67 ALSRRYVAECLAVARAEGARLDDDVVDEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRN 126 Query 215 GVIVRKARAHGLATPISDVLVPLLAAASDGPG 246 GVIVRKARAHGLATPISDVLVPLLAAASDGPG Sbjct 127 GVIVRKARAHGLATPISDVLVPLLAAASDGPG 158 >gi|148271549|ref|YP_001221110.1| 2-dehydropantoate 2-reductase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] gi|147829479|emb|CAN00392.1| 2-dehydropantoate 2-reductase [Clavibacter michiganensis subsp. michiganensis NCPPB 382] Length=297 Score = 278 bits (711), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 148/246 (61%), Positives = 174/246 (71%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV T P ++ PVD+++LAVKATQ +AA PWL LC TVV VLQNG+EQV V Sbjct 52 VVPGPVRTDPAGISAPVDLVLLAVKATQVEAAAPWLRALCHAGTVVVVLQNGIEQVGDVA 111 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PH P VVPA+VW AE + G V LRG+ + +P P + L G V+ D Sbjct 112 PHVPGCPVVPAVVWFPAEARADGSVLLRGDPRITLPDMPTSRVAVDALAGGRCRVELAAD 171 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F T AWRKL+ NA+AG M +GRR+ +FRRDDVA L+R Y ECLAVARAEGA LDD V Sbjct 172 FRTVAWRKLVQNAVAGIMAATGRRAGVFRRDDVAGLARGYARECLAVARAEGAHLDDGVA 231 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 D +V R+AP D GTS+LADR A RPLEW+ RNGVI+R+ARAHGL TPI DVLVPLLAA Sbjct 232 DRIVDDFRAAPADQGTSILADREAGRPLEWEARNGVILRRARAHGLPTPIGDVLVPLLAA 291 Query 241 ASDGPG 246 ASDGPG Sbjct 292 ASDGPG 297 >gi|221199031|ref|ZP_03572076.1| 2-dehydropantoate 2-reductase [Burkholderia multivorans CGD2M] gi|221205290|ref|ZP_03578306.1| 2-dehydropantoate 2-reductase [Burkholderia multivorans CGD2] gi|221175081|gb|EEE07512.1| 2-dehydropantoate 2-reductase [Burkholderia multivorans CGD2] gi|221181482|gb|EEE13884.1| 2-dehydropantoate 2-reductase [Burkholderia multivorans CGD2M] Length=298 Score = 275 bits (704), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 144/246 (59%), Positives = 172/246 (70%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV T P E+ VD++ L+VKATQ AA WLT L TVV VLQNG+EQ++ V Sbjct 53 VVPGPVRTDPAEIGRTVDLVFLSVKATQTAAAAEWLTALTGPETVVCVLQNGIEQLDTVA 112 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHC +VPA+VW A+ QP G VRLRG+ L +P A A LRG VD Sbjct 113 PHCSQGRIVPAVVWFPAQAQPDGSVRLRGDVRLSLPDTADARTVADALRGTRCAVDVTAA 172 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F++ AWRKLL NA+AG M L+ RR+ MF R D+A L+ Y+ ECLAVARAEGA L D+V Sbjct 173 FSSLAWRKLLQNAVAGLMALTVRRAGMFGRTDIAELALAYLRECLAVARAEGAELGDEVP 232 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E++ R+AP DMGTS+L DR A RPLEWD+RNGVI R+ RAHG+ TPISDVLVPLLAA Sbjct 233 QEILDKFRAAPADMGTSILTDREAGRPLEWDIRNGVISRRGRAHGIPTPISDVLVPLLAA 292 Query 241 ASDGPG 246 ASDGPG Sbjct 293 ASDGPG 298 >gi|170693852|ref|ZP_02885009.1| 2-dehydropantoate 2-reductase [Burkholderia graminis C4D1M] gi|170141270|gb|EDT09441.1| 2-dehydropantoate 2-reductase [Burkholderia graminis C4D1M] Length=298 Score = 275 bits (702), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 139/245 (57%), Positives = 174/245 (72%), Gaps = 0/245 (0%) Query 2 VPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQP 61 VPGPV T+P EV D++ +AVK+TQ DA PWL+ LC++ TVV VLQNGVEQ V P Sbjct 54 VPGPVRTNPAEVDNTFDLVFVAVKSTQIDATAPWLSALCNKNTVVCVLQNGVEQKALVAP 113 Query 62 HCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPDF 121 H P S V+P++VW A+ +P V LRG+A + +P P L G +VD DF Sbjct 114 HVPGSPVLPSVVWFPAQREPDASVWLRGKARITLPDTPETSLVLAALSGTRCSVDVAADF 173 Query 122 TTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVVD 181 T+ AWRKLL NA+AG MVL+GRR+ M+ R D+A L+ Y+ ECL VARAEGA L D+V Sbjct 174 TSVAWRKLLQNAVAGLMVLAGRRAGMYSRADIAGLALAYLQECLEVARAEGATLGDEVPQ 233 Query 182 EVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAAA 241 E+V R P D+GTS+LADR A RPLEWD RNGV+ R+AR+HG+ATPISD++VPLLAAA Sbjct 234 EIVDAFRGYPADLGTSILADREAGRPLEWDSRNGVVQRRARSHGIATPISDLVVPLLAAA 293 Query 242 SDGPG 246 SDGPG Sbjct 294 SDGPG 298 >gi|317405083|gb|EFV85429.1| 2-dehydropantoate 2-reductase [Achromobacter xylosoxidans C54] Length=298 Score = 270 bits (689), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 140/246 (57%), Positives = 174/246 (71%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P + +D++ +AVKATQ D+A WL LC TVV VLQNGVEQ+E+V Sbjct 53 VVPGPVHTDPARIDRKMDLIFVAVKATQTDSASGWLAALCRPDTVVCVLQNGVEQLERVA 112 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 H P + ++PA+VW A+ Q G VRLRG+A L +P PAA A LRG VD D Sbjct 113 MHAPPARIIPAVVWFPAQAQADGSVRLRGDARLSLPDMPAARVVAEALRGTQCVVDITED 172 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F + AWRKLL NA+AG M L+ RR+ MF R D+A LS Y+ ECL VARAEGARL D+V Sbjct 173 FPSVAWRKLLQNAVAGIMALTHRRAGMFARPDIAQLSLAYLRECLTVARAEGARLGDEVP 232 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E++ ++A D+ TS+L DR A R LEWD+RNGV+ R+ARAHG+ TPISD++VPLLAA Sbjct 233 QEILAKFQAAAPDLSTSILTDREAGRQLEWDIRNGVVSRRARAHGIPTPISDIIVPLLAA 292 Query 241 ASDGPG 246 ASDGPG Sbjct 293 ASDGPG 298 >gi|323524925|ref|YP_004227078.1| 2-dehydropantoate 2-reductase [Burkholderia sp. CCGE1001] gi|323381927|gb|ADX54018.1| 2-dehydropantoate 2-reductase [Burkholderia sp. CCGE1001] Length=298 Score = 266 bits (679), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 136/246 (56%), Positives = 172/246 (70%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV T P + D++ +AVK+TQ +A PWL+ LCD RTVV VLQNGVEQ++ + Sbjct 53 VVPGPVLTDPHGIRDKFDLVFVAVKSTQTASAAPWLSALCDARTVVCVLQNGVEQIDLFK 112 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P S V+P++VW A+ + V LR L +P PAA A LRG +V+ D Sbjct 113 PFASSGVVLPSVVWFPAQRESASSVWLRAAPRLTLPDVPAARVVASALRGTRCSVEVAED 172 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F + AWRKLL NA+AG MVL+GRR+ MF R D+ LS Y+ ECL VARAEGA+L DDV Sbjct 173 FVSVAWRKLLQNAVAGLMVLTGRRAGMFSRSDITTLSLAYLRECLDVARAEGAKLGDDVP 232 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 ++V +P D+GTS+LADR A+RPLEWD RNGV+ R+ R+HG+ATPISD+LVPLLAA Sbjct 233 QQIVDGFHRSPPDLGTSILADREANRPLEWDCRNGVVQRRGRSHGIATPISDLLVPLLAA 292 Query 241 ASDGPG 246 ASDGPG Sbjct 293 ASDGPG 298 >gi|339762711|gb|AEJ98931.1| 2-dehydropantoate 2-reductase [Klebsiella pneumoniae KCTC 2242] Length=298 Score = 265 bits (677), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 136/245 (56%), Positives = 172/245 (71%), Gaps = 0/245 (0%) Query 2 VPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQP 61 VPGPV T+P ++ VD++ LAVK+TQ DAA WL L TV+ VLQNGVEQ++++ Sbjct 54 VPGPVQTNPAQITRTVDLIFLAVKSTQIDAAAEWLRALTGPETVICVLQNGVEQLDRLAT 113 Query 62 HCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPDF 121 + +VPA+VW A+ Q G VRLRGEA L VP PA+ A L+G +VD +F Sbjct 114 YSLPGQIVPAVVWFPAQAQSDGSVRLRGEARLSVPDAPASRVVAAALQGTWCSVDLAANF 173 Query 122 TTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVVD 181 ++ AWRKL+ NA+AG M L+ RRS MF R D+A L+ Y+ ECLAVARAEGA L D+V Sbjct 174 SSLAWRKLMQNAVAGLMALTHRRSGMFGRADIARLTLAYLQECLAVARAEGAELGDEVPQ 233 Query 182 EVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAAA 241 E++ R+AP DM TS+L DR A RPLEWD+RNGVI R+ R H + TPISD+LVPLLAAA Sbjct 234 EILDKFRAAPADMSTSILTDREAGRPLEWDIRNGVIARRGRVHSIPTPISDILVPLLAAA 293 Query 242 SDGPG 246 SDGPG Sbjct 294 SDGPG 298 >gi|293607460|ref|ZP_06689798.1| ketopantoate reductase family oxidoreductase [Achromobacter piechaudii ATCC 43553] gi|292814162|gb|EFF73305.1| ketopantoate reductase family oxidoreductase [Achromobacter piechaudii ATCC 43553] Length=296 Score = 265 bits (677), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 136/246 (56%), Positives = 172/246 (70%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV T P+ + V ++ LAVKATQ D A WL LC TVV VLQNGVEQ+E V Sbjct 51 VVPGPVQTDPKRIDRTVGMVFLAVKATQTDTASEWLAALCRPDTVVCVLQNGVEQIEAVA 110 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 H P + +VPA+VW A+ Q G VRLRG+A L +P PA+ A L G+ V+ D Sbjct 111 AHAPRARIVPAVVWFPAQAQADGSVRLRGDARLSLPDTPASRVVAEALAGSQCAVEITAD 170 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F + AWRKLL NA+AG M L+ RR+ MF R D+A LS Y+ ECLAVARAEGARL D+ Sbjct 171 FLSVAWRKLLQNAVAGLMALTHRRAGMFARPDIAELSLAYLQECLAVARAEGARLGDETP 230 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E++ +++P D+ +S+L DR A RPLEW++RNGV+ R+ARAHG+ TPISD++V LLAA Sbjct 231 QEILAKFQASPADLSSSILTDREAGRPLEWNIRNGVVSRRARAHGIPTPISDIVVTLLAA 290 Query 241 ASDGPG 246 ASDGPG Sbjct 291 ASDGPG 296 >gi|206575388|ref|YP_002235557.1| putative 2-dehydropantoate 2-reductase [Klebsiella pneumoniae 342] gi|206570593|gb|ACI12222.1| putative 2-dehydropantoate 2-reductase [Klebsiella pneumoniae 342] Length=298 Score = 265 bits (676), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 136/245 (56%), Positives = 172/245 (71%), Gaps = 0/245 (0%) Query 2 VPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQP 61 VPGPV T+P ++ VD++ LAVK+TQ DAA WL L TV+ VLQNGVEQ++++ Sbjct 54 VPGPVQTNPAQITRTVDLIFLAVKSTQIDAAAEWLRALTGPETVICVLQNGVEQLDRLAT 113 Query 62 HCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPDF 121 + +VPA+VW A+ Q G VRLRGEA L VP PA+ A L+G +VD +F Sbjct 114 YSLPGQIVPAVVWFPAQAQSDGSVRLRGEARLSVPDAPASRVVAAALQGTWCSVDLAANF 173 Query 122 TTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVVD 181 ++ AWRKL+ NA+AG M L+ RRS MF R D+A L+ Y+ ECLAVARAEGA L D+V Sbjct 174 SSLAWRKLMQNAVAGLMALTHRRSGMFGRADIARLTLAYLQECLAVARAEGAELGDEVPQ 233 Query 182 EVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAAA 241 E++ R+AP DM TS+L DR A RPLEWD+RNGVI R+ R H + TPISD+LVPLLAAA Sbjct 234 EILDKFRAAPADMSTSILTDREAGRPLEWDIRNGVIARRGRVHSIPTPISDILVPLLAAA 293 Query 242 SDGPG 246 SDGPG Sbjct 294 SDGPG 298 >gi|221212150|ref|ZP_03585128.1| 2-dehydropantoate 2-reductase [Burkholderia multivorans CGD1] gi|221168235|gb|EEE00704.1| 2-dehydropantoate 2-reductase [Burkholderia multivorans CGD1] Length=298 Score = 263 bits (671), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 144/246 (59%), Positives = 171/246 (70%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV T P E+ VD++ L+VKATQ AA WL L TVV VLQNG+EQ++ V Sbjct 53 VVPGPVRTDPAEIDRTVDLVFLSVKATQTAAAAEWLAALTGPGTVVCVLQNGIEQLDTVA 112 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHC +VPA+VW A+ QP G VRLRG+ L +P A A LRG VD Sbjct 113 PHCSQGRIVPAVVWFPAQAQPDGSVRLRGDVRLNLPDTADARTVADALRGTRCAVDVTAA 172 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F++ AWRKLL NA+AG M L+ RRS MF R D+A L+ Y+ ECLAVARAEGA L D+V Sbjct 173 FSSLAWRKLLQNAVAGLMALTARRSGMFGRTDIAELALAYLRECLAVARAEGAELGDEVP 232 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E++ R+AP DMGTS+L DR A RPLEWD+RNGVI R+ RAHG+ TPISDVLVPLLAA Sbjct 233 QEILDKFRAAPADMGTSILTDREAGRPLEWDIRNGVISRRGRAHGIPTPISDVLVPLLAA 292 Query 241 ASDGPG 246 ASDGPG Sbjct 293 ASDGPG 298 >gi|317049124|ref|YP_004116772.1| 2-dehydropantoate 2-reductase [Pantoea sp. At-9b] gi|316950741|gb|ADU70216.1| 2-dehydropantoate 2-reductase [Pantoea sp. At-9b] Length=298 Score = 260 bits (665), Expect = 1e-67, Method: Compositional matrix adjust. Identities = 133/246 (55%), Positives = 164/246 (67%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 +VPGPV+T+P EV P D++ +AVK TQ PWLT LCD++TVV LQNGVEQ Q+ Sbjct 53 IVPGPVYTNPAEVPAPFDLVFVAVKTTQITDTAPWLTALCDKQTVVCALQNGVEQQAQLA 112 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P + V+P++VW A+ +P V LR + L +P P + LR VD D Sbjct 113 PFVSGATVLPSVVWFPAQREPDASVWLRAKPRLTLPDTPQTDLVLTALRDTRCQVDVSDD 172 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F T AWRKLL NA+AG MVL+ RR+ MF R D+ L+ Y+ ECL VARAEGA L D V Sbjct 173 FKTIAWRKLLQNAVAGLMVLANRRAGMFSRPDITGLALAYLRECLTVARAEGANLSDAVP 232 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E+V AP D+GTS+LADR A RPLEWD+RNGV+ R R HG+ATPISDV+VPLLAA Sbjct 233 QEIVDGFHRAPADLGTSILADRQADRPLEWDIRNGVVQRYGRTHGIATPISDVVVPLLAA 292 Query 241 ASDGPG 246 SDGPG Sbjct 293 GSDGPG 298 >gi|152970009|ref|YP_001335118.1| 2-dehydropantoate 2-reductase [Klebsiella pneumoniae subsp. pneumoniae MGH 78578] gi|150954858|gb|ABR76888.1| putative 2-dehydropantoate 2-reductase [Klebsiella pneumoniae subsp. pneumoniae MGH 78578] Length=296 Score = 259 bits (662), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 133/246 (55%), Positives = 165/246 (68%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P +A P D++ +AVK TQ +A PWLT LC TVV VLQNGVEQ +Q Sbjct 51 VVPGPVHTDPMAIAAPFDLVFVAVKTTQTEAIAPWLTALCSPDTVVCVLQNGVEQRQQFA 110 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P + V+P++VW A+ V LR L +P P AE+ L G VD D Sbjct 111 PLTGGATVLPSVVWFPAQRDADASVWLRATPRLTLPDLPGAERVQQALAGTRCAVDLAAD 170 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT AWRKLL NA+AG MVL+GRR+ MF R+D+ AL Y+ ECL VARAEGA L D+V Sbjct 171 FTTVAWRKLLQNAVAGLMVLTGRRAGMFAREDITALGLAYLRECLQVARAEGAALSDNVP 230 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 +E++ AP D+ TS+L DR RPLEWD+RNGV+ R+ R HG+ TP+SD++VPLLAA Sbjct 231 EEIIAGFHRAPADLSTSILIDRLNGRPLEWDIRNGVVQRRGRQHGIPTPLSDIIVPLLAA 290 Query 241 ASDGPG 246 ASDGPG Sbjct 291 ASDGPG 296 >gi|339761701|gb|AEJ97921.1| 2-dehydropantoate 2-reductase [Klebsiella pneumoniae KCTC 2242] Length=309 Score = 259 bits (662), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 133/246 (55%), Positives = 164/246 (67%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P +A P D++ +AVK TQ +A PWLT LC TVV VLQNGVEQ +Q Sbjct 64 VVPGPVHTDPMAIAAPFDLVFVAVKTTQTEAITPWLTALCSPDTVVCVLQNGVEQRQQFA 123 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P + V+P++VW A+ V LR L +P P AE+ L G VD D Sbjct 124 PLTGGATVLPSVVWFPAQRDADASVWLRATPRLTLPDLPGAERVQQALAGTRCAVDLAAD 183 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT AWRKLL NA+AG MVL+GRR+ MF R+D+ AL Y+ ECL VARAEGA L D V Sbjct 184 FTTVAWRKLLQNAVAGLMVLTGRRAGMFAREDITALGLAYLRECLQVARAEGAALSDSVP 243 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 +E++ AP D+ TS+L DR RPLEWD+RNGV+ R+ R HG+ TP+SD++VPLLAA Sbjct 244 EEIIAGFHRAPADLSTSILIDRLNGRPLEWDIRNGVVQRRGRQHGIPTPLSDIIVPLLAA 303 Query 241 ASDGPG 246 ASDGPG Sbjct 304 ASDGPG 309 >gi|290509798|ref|ZP_06549169.1| 2-dehydropantoate 2-reductase [Klebsiella sp. 1_1_55] gi|289779192|gb|EFD87189.1| 2-dehydropantoate 2-reductase [Klebsiella sp. 1_1_55] Length=296 Score = 259 bits (661), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 133/246 (55%), Positives = 164/246 (67%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P +A P D++ +AVK TQ +A PWLT LC TVV VLQNGVEQ +Q Sbjct 51 VVPGPVHTDPTAIAAPFDLVFVAVKTTQTEAIAPWLTALCSADTVVCVLQNGVEQRQQFA 110 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P + V+P++VW A+ V LR L +P P AE+ L G VD D Sbjct 111 PLTGGATVLPSVVWFPAQRDADASVWLRATPRLTLPDLPGAERVQQALAGTRCAVDLAAD 170 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT AWRKLL NA+AG MVL+GRR+ MF R+D+ AL Y+ ECL VARAEGA L D V Sbjct 171 FTTVAWRKLLQNAVAGLMVLTGRRAGMFAREDITALGLAYLRECLQVARAEGAALGDSVP 230 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 +E++ AP D+ TS+L DR RPLEWD+RNGV+ R+ R HG+ TP+SD++VPLLAA Sbjct 231 EEIIAGFHRAPADLSTSILIDRLNGRPLEWDIRNGVVQRRGRQHGIPTPLSDIIVPLLAA 290 Query 241 ASDGPG 246 ASDGPG Sbjct 291 ASDGPG 296 >gi|289570744|ref|ZP_06450971.1| conserved hypothetical protein [Mycobacterium tuberculosis T17] gi|289544498|gb|EFD48146.1| conserved hypothetical protein [Mycobacterium tuberculosis T17] Length=132 Score = 259 bits (661), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 131/132 (99%), Positives = 132/132 (100%), Gaps = 0/132 (0%) Query 115 VDCDPDFTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGAR 174 +DCDPDFTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGAR Sbjct 1 MDCDPDFTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGAR 60 Query 175 LDDDVVDEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVL 234 LDDDVVDEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVL Sbjct 61 LDDDVVDEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVL 120 Query 235 VPLLAAASDGPG 246 VPLLAAASDGPG Sbjct 121 VPLLAAASDGPG 132 >gi|238894476|ref|YP_002919210.1| 2-dehydropantoate 2-reductase [Klebsiella pneumoniae NTUH-K2044] gi|238546792|dbj|BAH63143.1| putative 2-dehydropantoate 2-reductase [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Length=274 Score = 258 bits (659), Expect = 6e-67, Method: Compositional matrix adjust. Identities = 132/246 (54%), Positives = 165/246 (68%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P +A P D++ +AVK TQ +A PWLT LC TVV VLQNGVEQ +Q Sbjct 29 VVPGPVHTDPMAIAAPFDLVFVAVKTTQTEAIAPWLTALCSPDTVVCVLQNGVEQRQQFA 88 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P + V+P++VW A+ V LR L +P P AE+ L G VD D Sbjct 89 PLTGGATVLPSVVWFPAQRDADASVWLRATPRLTLPDLPGAERVQQALAGTRCAVDLAAD 148 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT AWRKLL NA+AG MVL+GRR+ MF R+D+ AL Y+ ECL VARAEGA L D+V Sbjct 149 FTTVAWRKLLQNAVAGLMVLTGRRAGMFAREDITALGLAYMRECLQVARAEGAALSDNVP 208 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 +E++ AP D+ TS++ DR RPLEWD+RNGV+ R+ R HG+ TP+SD++VPLLAA Sbjct 209 EEIIAGFHRAPADLSTSIMIDRLNGRPLEWDIRNGVVQRRGRQHGIPTPLSDIIVPLLAA 268 Query 241 ASDGPG 246 ASDGPG Sbjct 269 ASDGPG 274 >gi|161523104|ref|YP_001586033.1| 2-dehydropantoate 2-reductase [Burkholderia multivorans ATCC 17616] gi|189348072|ref|YP_001941268.1| 2-dehydropantoate 2-reductase [Burkholderia multivorans ATCC 17616] gi|160346657|gb|ABX19741.1| 2-dehydropantoate 2-reductase [Burkholderia multivorans ATCC 17616] gi|189338210|dbj|BAG47278.1| 2-dehydropantoate 2-reductase [Burkholderia multivorans ATCC 17616] Length=298 Score = 257 bits (657), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 142/246 (58%), Positives = 168/246 (69%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV T P E+ VD++ L+VKATQ AA WL L T+V VLQNG+EQ + V Sbjct 53 VVPGPVRTDPAEIDRTVDLVFLSVKATQTAAAAEWLAALTGPETMVCVLQNGIEQSDTVA 112 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 PHC +VPA+VW A+ QP G VRLRGE L +P A A LRG VD Sbjct 113 PHCSQGRIVPAVVWFPAQAQPDGSVRLRGEVRLSLPDTADARTVADALRGTRCAVDVTAA 172 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F++ AWRKLL NA+AG M L+ RRS MF R D+A L+ Y+ ECLAVARAEGA L D+V Sbjct 173 FSSLAWRKLLQNAVAGLMALAVRRSGMFGRPDIAELALAYLRECLAVARAEGAELGDEVP 232 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 ++ R+AP DMGTS+L DR A RPLEWD+RNGVI R+ R HG+ TPISDVLVPLLAA Sbjct 233 QAILDKFRAAPADMGTSILTDREAGRPLEWDIRNGVISRRGRMHGIPTPISDVLVPLLAA 292 Query 241 ASDGPG 246 ASDGPG Sbjct 293 ASDGPG 298 >gi|239817272|ref|YP_002946182.1| 2-dehydropantoate 2-reductase [Variovorax paradoxus S110] gi|239803849|gb|ACS20916.1| 2-dehydropantoate 2-reductase [Variovorax paradoxus S110] Length=298 Score = 257 bits (656), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 139/245 (57%), Positives = 171/245 (70%), Gaps = 0/245 (0%) Query 2 VPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQP 61 VP PV P ++ G VD++ LAVKATQ +AA WL L +TVV VLQNGVEQ+E+V Sbjct 54 VPVPVRVDPIQIGGAVDLVFLAVKATQIEAAADWLAALGGPKTVVCVLQNGVEQLERVAL 113 Query 62 HCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPDF 121 H P++ VVPA+VW + Q G VRLR + L +P A A L+G V+ +F Sbjct 114 HAPAAQVVPAVVWFPVQAQADGSVRLRADMRLSLPDTSHARVVAEALQGTRCRVEPAANF 173 Query 122 TTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVVD 181 AWRKLL NA+AGFMVL+ RRS MF R D+AAL+ Y+ ECLAVARAEGA LDD V Sbjct 174 HALAWRKLLQNAVAGFMVLTQRRSGMFGRPDIAALALAYLRECLAVARAEGAELDDGVPQ 233 Query 182 EVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAAA 241 E++ ++AP DMGTS+L DR A RPLEWD+RNGV+ R+ RA G+ TPISD+LVPLLAAA Sbjct 234 EILDKFQAAPADMGTSILTDREAGRPLEWDIRNGVVARRGRARGVPTPISDMLVPLLAAA 293 Query 242 SDGPG 246 SDGPG Sbjct 294 SDGPG 298 >gi|242238390|ref|YP_002986571.1| 2-dehydropantoate 2-reductase [Dickeya dadantii Ech703] gi|242130447|gb|ACS84749.1| 2-dehydropantoate 2-reductase [Dickeya dadantii Ech703] Length=297 Score = 257 bits (656), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 135/246 (55%), Positives = 163/246 (67%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P + D++ +AVK+TQ A PWL+ LC +TVV VLQNGVEQ Sbjct 52 VVPGPVHTDPAGIKRMFDLVFIAVKSTQIAAVAPWLSALCSAKTVVCVLQNGVEQKALFA 111 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P+ +S V+P++VW A+ +P V LR A L +P P A L G VD D Sbjct 112 PYLSASLVLPSVVWFPAQREPDASVWLRENARLTLPDTPEARIVQTALHGTRCAVDVAAD 171 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT AWRKLL NA+ G MVL+GRR+ MF R D+ L+ Y+ ECLAVARAEGA L DDV Sbjct 172 FTTVAWRKLLQNAVGGLMVLAGRRAGMFSRADITGLALSYLQECLAVARAEGAALSDDVP 231 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E+V AP D+ TS+LADR A PLEWD RNGV+ R RAHG+ TPISD++VPLLAA Sbjct 232 REIVDRFHRAPADLSTSILADRQAGHPLEWDCRNGVVQRYGRAHGIPTPISDLIVPLLAA 291 Query 241 ASDGPG 246 ASDGPG Sbjct 292 ASDGPG 297 >gi|288935771|ref|YP_003439830.1| 2-dehydropantoate 2-reductase [Klebsiella variicola At-22] gi|288890480|gb|ADC58798.1| 2-dehydropantoate 2-reductase [Klebsiella variicola At-22] Length=296 Score = 257 bits (656), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 132/246 (54%), Positives = 164/246 (67%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P +A P D++ +AVK TQ +A WLT LC + TVV VLQNGVEQ +Q Sbjct 51 VVPGPVHTDPTAIAAPFDLVFVAVKTTQTEAIASWLTALCSKDTVVCVLQNGVEQRQQFA 110 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P + V+P++VW A+ V LR L +P P AE+ L G VD D Sbjct 111 PLTGGATVLPSVVWFPAQRDADASVWLRATPRLTLPDLPGAERVQQALAGTRCAVDLAAD 170 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT AWRKLL NA+AG MVL+GRR+ MF R+D+ AL Y+ ECL VARAEGA L D V Sbjct 171 FTTVAWRKLLQNAVAGLMVLTGRRAGMFAREDITALGLAYLRECLQVARAEGAALGDSVP 230 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 +E++ AP D+ TS+L DR RPLEWD+RNGV+ R+ R HG+ TP+SD++VPLLAA Sbjct 231 EEIIAGFHRAPADLSTSILIDRLNGRPLEWDIRNGVVQRRGRQHGIPTPLSDIIVPLLAA 290 Query 241 ASDGPG 246 ASDGPG Sbjct 291 ASDGPG 296 >gi|330015003|ref|ZP_08308036.1| 2-dehydropantoate 2-reductase [Klebsiella sp. MS 92-3] gi|328532436|gb|EGF59236.1| 2-dehydropantoate 2-reductase [Klebsiella sp. MS 92-3] Length=314 Score = 256 bits (655), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 131/246 (54%), Positives = 165/246 (68%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV+T P +A P D++ +AVK TQ +A PWLT LC TVV VLQNGVEQ +Q Sbjct 69 VVPGPVYTDPMAIAAPFDLVFVAVKTTQTEAIAPWLTALCSPDTVVCVLQNGVEQRQQFA 128 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P + V+P++VW A+ V LR L +P P AE+ L G VD D Sbjct 129 PLTGGATVLPSVVWFPAQRDADASVWLRATPRLTLPDLPGAERVQQALAGTRCAVDLAAD 188 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT AWRKLL NA+AG MVL+GRR+ MF R+D+ AL Y+ ECL VARAEGA L D+V Sbjct 189 FTTVAWRKLLQNAVAGLMVLTGRRAGMFAREDITALGLAYLRECLQVARAEGAALSDNVP 248 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 +E++ AP D+ TS++ DR RPLEWD+RNGV+ R+ R HG+ TP+SD++VPLLAA Sbjct 249 EEIIAGFHRAPADLSTSIMIDRLNGRPLEWDIRNGVVQRRGRQHGIPTPLSDIIVPLLAA 308 Query 241 ASDGPG 246 ASDGPG Sbjct 309 ASDGPG 314 >gi|333928084|ref|YP_004501663.1| 2-dehydropantoate 2-reductase [Serratia sp. AS12] gi|333933037|ref|YP_004506615.1| 2-dehydropantoate 2-reductase [Serratia sp. AS9] gi|333474644|gb|AEF46354.1| 2-dehydropantoate 2-reductase [Serratia sp. AS9] gi|333492144|gb|AEF51306.1| 2-dehydropantoate 2-reductase [Serratia sp. AS12] gi|333962241|gb|AEG29014.1| 2-dehydropantoate 2-reductase [Serratia sp. AS13] Length=296 Score = 256 bits (655), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 130/246 (53%), Positives = 170/246 (70%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV +P ++ P D++ +AVK TQ WL LCDE T+V LQNGVEQ Q++ Sbjct 51 VVPGPVLINPAAISHPFDLVFVAVKTTQVADCADWLAALCDENTLVCALQNGVEQETQLE 110 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P+ + V+P++VW A+ +P V LR + L +P P A++ A +L+G G TV+ D Sbjct 111 PYVNGAKVLPSVVWFPAQREPDASVWLRAKPRLTLPDVPQAKRVADVLKGTGCTVELSSD 170 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F + AWRKLL NA AG MVL+ RR+ MF R D+ L+ Y+ ECL VARA+GA L+D+V Sbjct 171 FLSIAWRKLLQNAAAGLMVLANRRAGMFSRGDITELALAYLRECLTVARAQGAVLNDNVP 230 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E+V R AP D+GTS+LADR A+RPLEWD+RNGV+ R R G+ATPISDVLVPLLAA Sbjct 231 QEIVDGFRHAPADLGTSILADRQANRPLEWDIRNGVVQRYGRLQGIATPISDVLVPLLAA 290 Query 241 ASDGPG 246 S+GPG Sbjct 291 GSEGPG 296 >gi|307729664|ref|YP_003906888.1| 2-dehydropantoate 2-reductase [Burkholderia sp. CCGE1003] gi|307584199|gb|ADN57597.1| 2-dehydropantoate 2-reductase [Burkholderia sp. CCGE1003] Length=298 Score = 256 bits (655), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 136/245 (56%), Positives = 168/245 (69%), Gaps = 0/245 (0%) Query 2 VPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQP 61 VPGPV T P + G VD++ +AVKATQ DAA PWL+ LCDE TVV VLQNGVEQ + V Sbjct 54 VPGPVLTDPAAIKGAVDLVFVAVKATQLDAAAPWLSALCDESTVVCVLQNGVEQKKLVAR 113 Query 62 HCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPDF 121 + + V+P++VW A+ + V LR + L +P P LR +VD DF Sbjct 114 YLSGNPVLPSVVWFPAQRESDASVWLRAQPRLTLPDAPETGVVLAALRDTRCSVDVQSDF 173 Query 122 TTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVVD 181 TT AWRKLL NA+AG MVL+GRR+ M+ R D+ LS Y+ ECL VARAEGA L D+V Sbjct 174 TTVAWRKLLQNAVAGLMVLAGRRAGMYSRPDITELSLAYLRECLEVARAEGAALGDEVPQ 233 Query 182 EVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAAA 241 E++ + AP D+GTS+LADR A RPLEWD RNGV+ R RAHG+ TPISD++VPLLAAA Sbjct 234 EILDGLLKAPPDLGTSILADRQAGRPLEWDCRNGVVQRCGRAHGIPTPISDLVVPLLAAA 293 Query 242 SDGPG 246 SDGPG Sbjct 294 SDGPG 298 >gi|206578066|ref|YP_002238841.1| 2-dehydropantoate 2-reductase [Klebsiella pneumoniae 342] gi|206567124|gb|ACI08900.1| putative 2-dehydropantoate 2-reductase [Klebsiella pneumoniae 342] Length=296 Score = 256 bits (653), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 132/246 (54%), Positives = 163/246 (67%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPVHT P +A P D++ +AVK TQ +A WLT LC TVV VLQNGVEQ +Q Sbjct 51 VVPGPVHTDPTAIAAPFDLVFVAVKTTQTEAIASWLTALCSTDTVVCVLQNGVEQRQQFA 110 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P + V+P++VW A+ V LR L +P P AE+ L G VD D Sbjct 111 PLTGGATVLPSVVWFPAQRDADASVWLRATPRLTLPDLPGAERVQQALAGTRCAVDLAAD 170 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FTT AWRKLL NA+AG MVL+GRR+ MF R+D+ AL Y+ ECL VARAEGA L D V Sbjct 171 FTTVAWRKLLQNAVAGLMVLTGRRAGMFAREDITALGLAYLRECLQVARAEGAALGDSVP 230 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 +E++ AP D+ TS+L DR RPLEWD+RNGV+ R+ R HG+ TP+SD++VPLLAA Sbjct 231 EEIIAGFHRAPADLSTSILIDRLNGRPLEWDIRNGVVQRRGRQHGIPTPLSDIIVPLLAA 290 Query 241 ASDGPG 246 ASDGPG Sbjct 291 ASDGPG 296 >gi|296103486|ref|YP_003613632.1| 2-dehydropantoate 2-reductase [Enterobacter cloacae subsp. cloacae ATCC 13047] gi|295057945|gb|ADF62683.1| 2-dehydropantoate 2-reductase [Enterobacter cloacae subsp. cloacae ATCC 13047] Length=296 Score = 256 bits (653), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 133/246 (55%), Positives = 169/246 (69%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV T P V P D++ +AVK TQN + WL LCDE TVV LQNGVEQ Q++ Sbjct 51 VVPGPVLTDPSVVTRPADLVFVAVKTTQNADSAGWLRTLCDENTVVCALQNGVEQKAQLE 110 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P + V+P++VW A+ +P V LR + L +P P A++ L+G V+ D Sbjct 111 PWVNGATVLPSVVWFPAQREPDASVWLRAKPRLTLPDVPQAKRVVDALQGTRCAVELSAD 170 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F T AWRKLL NA+AG MVL+ RR+ MF R+D++AL Y+ E LAVARAEGA L+DDV Sbjct 171 FATVAWRKLLQNAVAGLMVLANRRAGMFSREDISALGLAYLREGLAVARAEGAALNDDVA 230 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E++ + AP D+GTS+LADR A+RPLEWD+RNGVI R RAHG+ PISDV+VPLLAA Sbjct 231 QEILANFQRAPADLGTSILADRQANRPLEWDIRNGVIQRYGRAHGIPVPISDVIVPLLAA 290 Query 241 ASDGPG 246 S+GPG Sbjct 291 GSEGPG 296 >gi|172065408|ref|YP_001816120.1| 2-dehydropantoate 2-reductase [Burkholderia ambifaria MC40-6] gi|171997650|gb|ACB68567.1| 2-dehydropantoate 2-reductase [Burkholderia ambifaria MC40-6] Length=298 Score = 255 bits (652), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 133/246 (55%), Positives = 166/246 (68%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV T P+ V D++ +AVK+TQ +A PW+ LCD TVV VLQNGVEQ Sbjct 53 VVPGPVRTDPQAVKERFDLVFVAVKSTQVASAAPWIPALCDANTVVCVLQNGVEQTGAFA 112 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P+ +A+VP++VW A+ + V LRG+ L VP PA+ LRG V+ D Sbjct 113 PYVAGAAIVPSVVWFPAQRESDASVWLRGKPRLTVPDTPASNVVVSALRGTRCPVEVADD 172 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F + AWRKLL NA+AG MVL+GRR+ MF R D+ LS Y+ ECL VARAEGA+L DDV Sbjct 173 FVSLAWRKLLQNAVAGLMVLTGRRAGMFTRSDITELSLAYLRECLEVARAEGAKLGDDVP 232 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E+V P D+GTS+LADR +RPLEWD RNGV+ R R+HG+ TPISD++VPLLAA Sbjct 233 QEIVDGFHRFPPDLGTSILADRQGNRPLEWDCRNGVVQRCGRSHGIPTPISDLVVPLLAA 292 Query 241 ASDGPG 246 ASDGPG Sbjct 293 ASDGPG 298 >gi|293395438|ref|ZP_06639722.1| ketopantoate reductase family oxidoreductase [Serratia odorifera DSM 4582] gi|291422122|gb|EFE95367.1| ketopantoate reductase family oxidoreductase [Serratia odorifera DSM 4582] Length=296 Score = 255 bits (651), Expect = 5e-66, Method: Compositional matrix adjust. Identities = 130/246 (53%), Positives = 168/246 (69%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGPV ++P + P D++ +AVK TQ + WL LC+E TVV LQNGVEQ Q+ Sbjct 51 VVPGPVLSNPAAIRQPFDLVFVAVKTTQITDSADWLAALCNENTVVCALQNGVEQQTQLA 110 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P+ + V+P++VW A+ +P V LR + L +P P+A + L G+G TV+ D Sbjct 111 PYVNGATVLPSVVWFPAQREPDASVWLRAKPRLTLPAVPSATRVTDALGGSGCTVELSAD 170 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 F T AWRKLL NA+AG MVL+ RR+ MF R D+ AL+ Y+ ECLAVAR +GA+LDD+V Sbjct 171 FLTIAWRKLLQNAVAGLMVLANRRTGMFARPDITALALAYLHECLAVARTQGAKLDDNVP 230 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E+V AP D+GTS+LADR A+RPLEWD+RNGVI R R G+ TPI DVLVPLLAA Sbjct 231 QEIVDGFHRAPADLGTSILADRQANRPLEWDIRNGVIQRYGRLQGIPTPIGDVLVPLLAA 290 Query 241 ASDGPG 246 S+GPG Sbjct 291 GSEGPG 296 >gi|187919858|ref|YP_001888889.1| 2-dehydropantoate 2-reductase [Burkholderia phytofirmans PsJN] gi|187718296|gb|ACD19519.1| 2-dehydropantoate 2-reductase [Burkholderia phytofirmans PsJN] Length=298 Score = 254 bits (650), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 129/246 (53%), Positives = 166/246 (68%), Gaps = 0/246 (0%) Query 1 VVPGPVHTSPREVAGPVDVLILAVKATQNDAARPWLTRLCDERTVVAVLQNGVEQVEQVQ 60 VVPGP T P E+ D++++AVK+TQ AA PW + LC +TVV +LQNGV+Q V Sbjct 53 VVPGPAQTDPAEIKNTFDLVLVAVKSTQVKAAAPWFSALCSHKTVVCMLQNGVDQKALVA 112 Query 61 PHCPSSAVVPAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPD 120 P+ + V+P++VW A+ P V LRG+ L +P P LRG +VD D Sbjct 113 PYLSGNPVLPSVVWFPAQRDPDASVWLRGKPRLTLPDTPGIAVVLAALRGTRVSVDIAAD 172 Query 121 FTTAAWRKLLVNALAGFMVLSGRRSAMFRRDDVAALSRRYVAECLAVARAEGARLDDDVV 180 FT+ AWRKLL NA+AG MVL+GRR+ MF R D+ LS Y+ ECL VARAEGA L D+V Sbjct 173 FTSVAWRKLLQNAVAGLMVLTGRRAGMFSRTDITTLSLAYLRECLEVARAEGATLGDEVP 232 Query 181 DEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRKARAHGLATPISDVLVPLLAA 240 E+V R +P D+GTS+LADR RPLEW+ RNGV+ ++ R HG+ TPISD++VPLLAA Sbjct 233 QEIVDGFRDSPPDLGTSILADRLGGRPLEWESRNGVVQQRGRLHGIPTPISDLVVPLLAA 292 Query 241 ASDGPG 246 ASDGPG Sbjct 293 ASDGPG 298 Lambda K H 0.321 0.134 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 346350635400 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40