BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2583c

Length=790
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15842122|ref|NP_337159.1|  GTP pyrophosphokinase [Mycobacteriu...  1612    0.0  
gi|15609720|ref|NP_217099.1|  GTP pyrophosphokinase [Mycobacteriu...  1611    0.0  
gi|289751206|ref|ZP_06510584.1|  GTP pyrophosphokinase relA [Myco...  1607    0.0  
gi|341602506|emb|CCC65182.1|  probable GTP pyrophosphokinase relA...  1605    0.0  
gi|289762754|ref|ZP_06522132.1|  GTP pyrophosphokinase relA [Myco...  1527    0.0  
gi|313104173|sp|P66014.2|RELA_MYCTU  RecName: Full=Bifunctional (...  1513    0.0  
gi|240171981|ref|ZP_04750640.1|  GTP pyrophosphokinase RelA [Myco...  1493    0.0  
gi|342858592|ref|ZP_08715247.1|  GTP pyrophosphokinase [Mycobacte...  1485    0.0  
gi|254775911|ref|ZP_05217427.1|  GTP pyrophosphokinase [Mycobacte...  1484    0.0  
gi|15827167|ref|NP_301430.1|  GTP pyrophosphokinase [Mycobacteriu...  1484    0.0  
gi|118467123|ref|YP_882646.1|  GTP pyrophosphokinase [Mycobacteri...  1483    0.0  
gi|336461524|gb|EGO40392.1|  (p)ppGpp synthetase, RelA/SpoT famil...  1483    0.0  
gi|41407145|ref|NP_959981.1|  RelA [Mycobacterium avium subsp. pa...  1483    0.0  
gi|183982138|ref|YP_001850429.1|  GTP pyrophosphokinase RelA [Myc...  1480    0.0  
gi|254820460|ref|ZP_05225461.1|  GTP pyrophosphokinase [Mycobacte...  1477    0.0  
gi|118617353|ref|YP_905685.1|  GTP pyrophosphokinase RelA [Mycoba...  1476    0.0  
gi|296170827|ref|ZP_06852392.1|  GTP diphosphokinase [Mycobacteri...  1472    0.0  
gi|120403572|ref|YP_953401.1|  (p)ppGpp synthetase I SpoT/RelA [M...  1407    0.0  
gi|108799247|ref|YP_639444.1|  (p)ppGpp synthetase I SpoT/RelA [M...  1405    0.0  
gi|126434905|ref|YP_001070596.1|  (p)ppGpp synthetase I SpoT/RelA...  1404    0.0  
gi|118471771|ref|YP_887284.1|  GTP pyrophosphokinase [Mycobacteri...  1404    0.0  
gi|145224394|ref|YP_001135072.1|  (p)ppGpp synthetase I SpoT/RelA...  1397    0.0  
gi|169629960|ref|YP_001703609.1|  GTP pyrophosphokinase [Mycobact...  1395    0.0  
gi|333991010|ref|YP_004523624.1|  GTP pyrophosphokinase RelA [Myc...  1389    0.0  
gi|289444121|ref|ZP_06433865.1|  GTP pyrophosphokinase relA [Myco...  1355    0.0  
gi|111023852|ref|YP_706824.1|  GTP diphosphokinase [Rhodococcus j...  1348    0.0  
gi|226366288|ref|YP_002784071.1|  GTP pyrophosphokinase/guanosine...  1347    0.0  
gi|312139501|ref|YP_004006837.1|  gtp diphosphokinase/guanosine-3...  1336    0.0  
gi|308374621|ref|ZP_07667828.1|  GTP pyrophosphokinase relA [Myco...  1322    0.0  
gi|229492002|ref|ZP_04385819.1|  RelA/SpoT family protein [Rhodoc...  1314    0.0  
gi|226306418|ref|YP_002766378.1|  GTP pyrophosphokinase/guanosine...  1312    0.0  
gi|54025654|ref|YP_119896.1|  putative ppGpp synthetase [Nocardia...  1286    0.0  
gi|296139654|ref|YP_003646897.1|  (p)ppGpp synthetase I SpoT/RelA...  1284    0.0  
gi|343924320|ref|ZP_08763871.1|  GTP pyrophosphokinase/guanosine-...  1283    0.0  
gi|333919490|ref|YP_004493071.1|  GTP diphosphokinase [Amycolicic...  1278    0.0  
gi|262202238|ref|YP_003273446.1|  RelA/SpoT family protein [Gordo...  1272    0.0  
gi|326382134|ref|ZP_08203826.1|  RelA/SpoT family protein [Gordon...  1233    0.0  
gi|134098602|ref|YP_001104263.1|  GTP pyrophosphokinase [Saccharo...  1211    0.0  
gi|296393867|ref|YP_003658751.1|  (p)ppGpp synthetase I [Segnilip...  1202    0.0  
gi|317508687|ref|ZP_07966342.1|  RelA/SpoT family protein [Segnil...  1194    0.0  
gi|331697364|ref|YP_004333603.1|  (p)ppGpp synthetase I, SpoT/Rel...  1193    0.0  
gi|256375833|ref|YP_003099493.1|  (p)ppGpp synthetase I SpoT/RelA...  1192    0.0  
gi|257055543|ref|YP_003133375.1|  (p)ppGpp synthetase, RelA/SpoT ...  1177    0.0  
gi|300787167|ref|YP_003767458.1|  GTP pyrophosphokinase [Amycolat...  1170    0.0  
gi|302527845|ref|ZP_07280187.1|  GTP pyrophosphokinase [Streptomy...  1167    0.0  
gi|324999169|ref|ZP_08120281.1|  (p)ppGpp synthetase I, SpoT/RelA...  1128    0.0  
gi|319947807|ref|ZP_08022001.1|  GTP diphosphokinase [Dietzia cin...  1109    0.0  
gi|258653541|ref|YP_003202697.1|  (p)ppGpp synthetase I SpoT/RelA...  1085    0.0  
gi|213966136|ref|ZP_03394323.1|  RelA/SpoT family protein [Coryne...  1079    0.0  
gi|284991594|ref|YP_003410148.1|  (p)ppGpp synthetase I SpoT/RelA...  1071    0.0  


>gi|15842122|ref|NP_337159.1| GTP pyrophosphokinase [Mycobacterium tuberculosis CDC1551]
 gi|253798336|ref|YP_003031337.1| GTP pyrophosphokinase relA [Mycobacterium tuberculosis KZN 1435]
 gi|254232702|ref|ZP_04926029.1| GTP pyrophosphokinase relA [Mycobacterium tuberculosis C]
 9 more sequence titles
 Length=793

 Score = 1612 bits (4174),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 790/790 (100%), Positives = 790/790 (100%), Gaps = 0/790 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT
Sbjct  4    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  63

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG
Sbjct  64   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  123

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  124  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  183

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  184  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  243

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS
Sbjct  244  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  303

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  304  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  363

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM
Sbjct  364  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  423

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE
Sbjct  424  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  483

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF
Sbjct  484  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  543

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV
Sbjct  544  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  603

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660
            SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC
Sbjct  604  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  663

Query  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720
            TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL
Sbjct  664  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  723

Query  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780
            DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV
Sbjct  724  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  783

Query  781  YDVYRVTSAA  790
            YDVYRVTSAA
Sbjct  784  YDVYRVTSAA  793


>gi|15609720|ref|NP_217099.1| GTP pyrophosphokinase [Mycobacterium tuberculosis H37Rv]
 gi|31793767|ref|NP_856260.1| GTP pyrophosphokinase [Mycobacterium bovis AF2122/97]
 gi|121638468|ref|YP_978692.1| putative GTP pyrophosphokinase relA [Mycobacterium bovis BCG 
str. Pasteur 1173P2]
 58 more sequence titles
 Length=790

 Score = 1611 bits (4171),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 789/790 (99%), Positives = 790/790 (100%), Gaps = 0/790 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            +AEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT
Sbjct  1    MAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG
Sbjct  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS
Sbjct  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM
Sbjct  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE
Sbjct  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF
Sbjct  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV
Sbjct  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660
            SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC
Sbjct  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660

Query  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720
            TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL
Sbjct  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720

Query  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780
            DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV
Sbjct  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780

Query  781  YDVYRVTSAA  790
            YDVYRVTSAA
Sbjct  781  YDVYRVTSAA  790


>gi|289751206|ref|ZP_06510584.1| GTP pyrophosphokinase relA [Mycobacterium tuberculosis T92]
 gi|289691793|gb|EFD59222.1| GTP pyrophosphokinase relA [Mycobacterium tuberculosis T92]
Length=790

 Score = 1607 bits (4161),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 788/790 (99%), Positives = 789/790 (99%), Gaps = 0/790 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            +AEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT
Sbjct  1    MAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG
Sbjct  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS
Sbjct  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM
Sbjct  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE
Sbjct  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF
Sbjct  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV
Sbjct  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660
            SAKHVVQRLLAELGGIDQAEEELAERSTPATMP RPRSTDDVGVSVPGAPGVLTKLAKCC
Sbjct  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPWRPRSTDDVGVSVPGAPGVLTKLAKCC  660

Query  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720
            TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL
Sbjct  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720

Query  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780
            DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV
Sbjct  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780

Query  781  YDVYRVTSAA  790
            YDVYRVTSAA
Sbjct  781  YDVYRVTSAA  790


>gi|341602506|emb|CCC65182.1| probable GTP pyrophosphokinase relA [Mycobacterium bovis BCG 
str. Moreau RDJ]
Length=790

 Score = 1605 bits (4156),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 787/790 (99%), Positives = 789/790 (99%), Gaps = 0/790 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            +AEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT
Sbjct  1    MAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            NPVL+PLVAVHREIYPKAD SILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG
Sbjct  61   NPVLKPLVAVHREIYPKADPSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS
Sbjct  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM
Sbjct  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE
Sbjct  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF
Sbjct  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV
Sbjct  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660
            SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC
Sbjct  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660

Query  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720
            TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL
Sbjct  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720

Query  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780
            DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV
Sbjct  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780

Query  781  YDVYRVTSAA  790
            YDVYRVTSAA
Sbjct  781  YDVYRVTSAA  790


>gi|289762754|ref|ZP_06522132.1| GTP pyrophosphokinase relA [Mycobacterium tuberculosis GM 1503]
 gi|289710260|gb|EFD74276.1| GTP pyrophosphokinase relA [Mycobacterium tuberculosis GM 1503]
Length=746

 Score = 1527 bits (3953),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 745/746 (99%), Positives = 746/746 (100%), Gaps = 0/746 (0%)

Query  45   VRARLARRMTAQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDP  104
            +RARLARRMTAQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDP
Sbjct  1    MRARLARRMTAQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDP  60

Query  105  YITHPLAVANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLD  164
            YITHPLAVANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLD
Sbjct  61   YITHPLAVANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLD  120

Query  165  RVVLGSAAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVI  224
            RVVLGSAAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVI
Sbjct  121  RVVLGSAAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVI  180

Query  225  APLAHRLGMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTA  284
            APLAHRLGMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTA
Sbjct  181  APLAHRLGMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTA  240

Query  285  SKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQP  344
            SKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQP
Sbjct  241  SKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQP  300

Query  345  MAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKG  404
            MAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKG
Sbjct  301  MAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKG  360

Query  405  RNGVLHPHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITL  464
            RNGVLHPHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITL
Sbjct  361  RNGVLHPHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITL  420

Query  465  PTGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQ  524
            PTGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQ
Sbjct  421  PTGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQ  480

Query  525  QFVVSPRAKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELH  584
            QFVVSPRAKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELH
Sbjct  481  QFVVSPRAKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELH  540

Query  585  YADVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGV  644
            YADVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGV
Sbjct  541  YADVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGV  600

Query  645  SVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWA  704
            SVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWA
Sbjct  601  SVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWA  660

Query  705  PSPSSVFLVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDP  764
            PSPSSVFLVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDP
Sbjct  661  PSPSSVFLVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDP  720

Query  765  KHLGHLLNAVRNVEGVYDVYRVTSAA  790
            KHLGHLLNAVRNVEGVYDVYRVTSAA
Sbjct  721  KHLGHLLNAVRNVEGVYDVYRVTSAA  746


>gi|313104173|sp|P66014.2|RELA_MYCTU RecName: Full=Bifunctional (p)ppGpp synthase/hydrolase relA; 
Includes: RecName: Full=GTP pyrophosphokinase; AltName: Full=(p)ppGpp 
synthase; AltName: Full=ATP:GTP 3'-pyrophosphotransferase; 
AltName: Full=Stringent response-like protein; AltName: 
Full=ppGpp synthase II; Includes: RecName: Full=Guanosine-3',5'-bis(diphosphate) 
3'-pyrophosphohydrolase; AltName: 
Full=Penta-phosphate guanosine-3'-pyrophosphohydrolase; Short=(ppGpp)ase
Length=738

 Score = 1513 bits (3917),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 738/738 (100%), Positives = 738/738 (100%), Gaps = 0/738 (0%)

Query  53   MTAQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAV  112
            MTAQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAV
Sbjct  1    MTAQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAV  60

Query  113  ANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAA  172
            ANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAA
Sbjct  61   ANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAA  120

Query  173  EGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG  232
            EGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG
Sbjct  121  EGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG  180

Query  233  MASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVE  292
            MASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVE
Sbjct  181  MASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVE  240

Query  293  GRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDY  352
            GRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDY
Sbjct  241  GRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDY  300

Query  353  IAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPH  412
            IAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPH
Sbjct  301  IAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPH  360

Query  413  AAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVD  472
            AAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVD
Sbjct  361  AAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVD  420

Query  473  FAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRA  532
            FAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRA
Sbjct  421  FAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRA  480

Query  533  KTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALY  592
            KTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALY
Sbjct  481  KTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALY  540

Query  593  TAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGV  652
            TAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGV
Sbjct  541  TAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGV  600

Query  653  LTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFL  712
            LTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFL
Sbjct  601  LTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFL  660

Query  713  VAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN  772
            VAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN
Sbjct  661  VAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN  720

Query  773  AVRNVEGVYDVYRVTSAA  790
            AVRNVEGVYDVYRVTSAA
Sbjct  721  AVRNVEGVYDVYRVTSAA  738


>gi|240171981|ref|ZP_04750640.1| GTP pyrophosphokinase RelA [Mycobacterium kansasii ATCC 12478]
Length=786

 Score = 1493 bits (3866),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 744/790 (95%), Positives = 759/790 (97%), Gaps = 6/790 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPE-SPVETLKTSISASRRVRARLARRMTAQRST  59
            +A+DQ  AQAV  P EA     P +E PE SPVETLKTS SASRRVRARLARRMTA+   
Sbjct  1    MADDQNAAQAVVSPIEA-----PPVEAPEPSPVETLKTSSSASRRVRARLARRMTARSGA  55

Query  60   TNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAEL  119
             NPVLEPLVAVHREIYPKADLS+LQRAYEVADQRHA Q R SGDPYITHPLAVANILAEL
Sbjct  56   INPVLEPLVAVHREIYPKADLSMLQRAYEVADQRHAGQFRHSGDPYITHPLAVANILAEL  115

Query  120  GMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRK  179
            GMDTTTLVAALLHDTVEDTGYTLEAL+E+FGEEVGHLVDGVTKLDRVVLGSAAEGETIRK
Sbjct  116  GMDTTTLVAALLHDTVEDTGYTLEALSEDFGEEVGHLVDGVTKLDRVVLGSAAEGETIRK  175

Query  180  MITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWE  239
            MI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWE
Sbjct  176  MIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWE  235

Query  240  LEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYW  299
            LEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVR EI+NTL ASKIKATVEGRPKHYW
Sbjct  236  LEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRTEIINTLGASKIKATVEGRPKHYW  295

Query  300  SIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYG  359
            SIYQKMIVKGRDFDDIHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYG
Sbjct  296  SIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYG  355

Query  360  VYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDD  419
            VYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGV HPHAAAEIDD
Sbjct  356  VYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDD  415

Query  420  MAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHT  479
            MAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHT
Sbjct  416  MAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHT  475

Query  480  EVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQW  539
            EVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQW
Sbjct  476  EVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQW  535

Query  540  FAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGH  599
            FAKERREEALETGK+AMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGH
Sbjct  536  FAKERREEALETGKEAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGH  595

Query  600  VSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKC  659
            VSA+HV+QRLLAELGGIDQAEEELAERSTP TMPRR RS+DDVGVSVPGAPGVLTKLAKC
Sbjct  596  VSARHVMQRLLAELGGIDQAEEELAERSTPTTMPRRQRSSDDVGVSVPGAPGVLTKLAKC  655

Query  660  CTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEA  719
            CTPVPGD IMGFVTRGGGVSVHRTDCTNA SLQQQAERIIEVLWAPSP+SVFLVAIQVEA
Sbjct  656  CTPVPGDQIMGFVTRGGGVSVHRTDCTNATSLQQQAERIIEVLWAPSPTSVFLVAIQVEA  715

Query  720  LDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEG  779
            LDRHRLLSD+TR LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN VRNVEG
Sbjct  716  LDRHRLLSDITRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEG  775

Query  780  VYDVYRVTSA  789
            VYDVYRVTSA
Sbjct  776  VYDVYRVTSA  785


>gi|342858592|ref|ZP_08715247.1| GTP pyrophosphokinase [Mycobacterium colombiense CECT 3035]
 gi|342134296|gb|EGT87476.1| GTP pyrophosphokinase [Mycobacterium colombiense CECT 3035]
Length=792

 Score = 1485 bits (3845),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 737/792 (94%), Positives = 762/792 (97%), Gaps = 2/792 (0%)

Query  1    VAEDQLTAQAVAPPTEA--SAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRS  58
            +A++   AQA+  PT+A  S A+   +E PE P E+LKTS SASRRVRARLARRMTAQRS
Sbjct  1    MADENSAAQALDAPTKAPESPAITQPMEIPEPPAESLKTSSSASRRVRARLARRMTAQRS  60

Query  59   TTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAE  118
            T NPVLEPLVAVHREIYPKA++S+L RA+EVADQRHA+QLR SGDPYITHPLAVA ILAE
Sbjct  61   TLNPVLEPLVAVHREIYPKANVSLLSRAFEVADQRHATQLRHSGDPYITHPLAVATILAE  120

Query  119  LGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIR  178
            LGMDTTTLVAALLHDTVEDTGYTL+AL+EEFGEEVGHLVDGVTKLDRVVLGSAAEGETIR
Sbjct  121  LGMDTTTLVAALLHDTVEDTGYTLDALSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIR  180

Query  179  KMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKW  238
            KMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKW
Sbjct  181  KMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKW  240

Query  239  ELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHY  298
            ELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTL+ASKIKATVEGRPKHY
Sbjct  241  ELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLSASKIKATVEGRPKHY  300

Query  299  WSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRY  358
            WSIYQKMIVKGRDFDDIHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRY
Sbjct  301  WSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRY  360

Query  359  GVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEID  418
            GVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNG+ HPHAAAEID
Sbjct  361  GVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGLPHPHAAAEID  420

Query  419  DMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVH  478
            DMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLP GSTPVDFAYAVH
Sbjct  421  DMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPNGSTPVDFAYAVH  480

Query  479  TEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQ  538
            TEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKA NAGPSRDWQQFVVSPRAK KIRQ
Sbjct  481  TEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQQFVVSPRAKAKIRQ  540

Query  539  WFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEG  598
            WFAKERREEALE+GKDAMAREVRRGGLPLQRLVNGE++AAVARELHY DVSALYTAIGEG
Sbjct  541  WFAKERREEALESGKDAMAREVRRGGLPLQRLVNGETLAAVARELHYTDVSALYTAIGEG  600

Query  599  HVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAK  658
            HVSA+HVVQRLLAELGGIDQAEE+LAERSTP TM RRPRS+DDVGVSVPGAPGVLTKLAK
Sbjct  601  HVSARHVVQRLLAELGGIDQAEEDLAERSTPTTMLRRPRSSDDVGVSVPGAPGVLTKLAK  660

Query  659  CCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVE  718
            CCTPVPGD IMGFVTRGGGVSVHRTDCTNAASLQQQ+ERIIEV WAPSPSSVFLVAIQVE
Sbjct  661  CCTPVPGDQIMGFVTRGGGVSVHRTDCTNAASLQQQSERIIEVHWAPSPSSVFLVAIQVE  720

Query  719  ALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVE  778
            ALDRHRLLSDVTR LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN VRNVE
Sbjct  721  ALDRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVE  780

Query  779  GVYDVYRVTSAA  790
            GVYDVYRVTSAA
Sbjct  781  GVYDVYRVTSAA  792


>gi|254775911|ref|ZP_05217427.1| GTP pyrophosphokinase [Mycobacterium avium subsp. avium ATCC 
25291]
Length=788

 Score = 1484 bits (3842),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 736/790 (94%), Positives = 757/790 (96%), Gaps = 2/790 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            +AE+   AQA+  P E+     P +ETPE P E+LKTS SASRRVRARLARRMTAQRST 
Sbjct  1    MAEENSAAQALDAPAESPP--NPVIETPEPPTESLKTSSSASRRVRARLARRMTAQRSTL  58

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            NPVLEPLVA+HREIYPKA++ +LQRA+EVADQRHASQLR SGDPYITHPLAVA ILAELG
Sbjct  59   NPVLEPLVAMHREIYPKANVQLLQRAFEVADQRHASQLRHSGDPYITHPLAVATILAELG  118

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MDTTTLVAALLHDTVEDTGYTL  L+EEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  119  MDTTTLVAALLHDTVEDTGYTLAQLSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  178

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  179  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  238

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKY+EIVRLVAGRAPSRDTYLAKVRAEI+NTL ASKIKATVEGRPKHYWS
Sbjct  239  EDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIINTLNASKIKATVEGRPKHYWS  298

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFDDIHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  299  IYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  358

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGV HPHAAAEIDDM
Sbjct  359  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDM  418

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTP+DFAYAVHTE
Sbjct  419  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPIDFAYAVHTE  478

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGEVVEVFTSKA NAGPSRDWQQFVVSPRAK KIRQWF
Sbjct  479  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQQFVVSPRAKAKIRQWF  538

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALE GKDAMAREVRRGGLPLQRLVN ESM+AVARELHYADVSALYTAIGEGHV
Sbjct  539  AKERREEALEAGKDAMAREVRRGGLPLQRLVNAESMSAVARELHYADVSALYTAIGEGHV  598

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660
            SA+HVVQRLLAELGGIDQAEE+LAERSTP TM RRPRS+DDVGVSVPGAPGVLTKLAKCC
Sbjct  599  SARHVVQRLLAELGGIDQAEEDLAERSTPTTMLRRPRSSDDVGVSVPGAPGVLTKLAKCC  658

Query  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720
            TPVPGD IMGFVTRGGGVSVHRTDCTNAASLQQQ+ERIIEV WAPSPSSVFLVAIQVEAL
Sbjct  659  TPVPGDQIMGFVTRGGGVSVHRTDCTNAASLQQQSERIIEVHWAPSPSSVFLVAIQVEAL  718

Query  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780
            DRHRLLSDVTR LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN VRNVEGV
Sbjct  719  DRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGV  778

Query  781  YDVYRVTSAA  790
            YDVYRVTSAA
Sbjct  779  YDVYRVTSAA  788


>gi|15827167|ref|NP_301430.1| GTP pyrophosphokinase [Mycobacterium leprae TN]
 gi|221229645|ref|YP_002503061.1| putative GTP pyrophosphokinase [Mycobacterium leprae Br4923]
 gi|2498842|sp|Q49640.1|RELA_MYCLE RecName: Full=Probable GTP pyrophosphokinase; AltName: Full=(p)ppGpp 
synthase; AltName: Full=ATP:GTP 3'-pyrophosphotransferase; 
AltName: Full=ppGpp synthase I
 gi|466814|gb|AAA17089.1| spoT [Mycobacterium leprae]
 gi|3136012|emb|CAA19084.1| GTP pyrophosphokinase [Mycobacterium leprae]
 gi|13092715|emb|CAC29999.1| putative GTP pyrophosphokinase [Mycobacterium leprae]
 gi|219932752|emb|CAR70584.1| putative GTP pyrophosphokinase [Mycobacterium leprae Br4923]
Length=787

 Score = 1484 bits (3842),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 738/790 (94%), Positives = 761/790 (97%), Gaps = 3/790 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            +A+DQ TAQA+ P         PA+E PE+PVETLKTS SASRRVRARLARRMTAQRST 
Sbjct  1    MADDQGTAQALQP---VQVVPGPAVEAPETPVETLKTSSSASRRVRARLARRMTAQRSTI  57

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            +PVLEPLVAVH+E YPKA+LSI+QRA+EVADQRHASQLR+SGDPYITHPLAVANILAELG
Sbjct  58   SPVLEPLVAVHKEFYPKANLSIVQRAFEVADQRHASQLRRSGDPYITHPLAVANILAELG  117

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MD TTLVAALLHDTVEDTGYTLEAL+EEFG+EVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  118  MDITTLVAALLHDTVEDTGYTLEALSEEFGDEVGHLVDGVTKLDRVVLGSAAEGETIRKM  177

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  178  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  237

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEI++TL ASKIKATVEGRPKHYWS
Sbjct  238  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIISTLGASKIKATVEGRPKHYWS  297

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFDDIHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  298  IYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  357

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM
Sbjct  358  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  417

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAA+PGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE
Sbjct  418  AWMRQLLDWQREAAEPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  477

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGE VE+FTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF
Sbjct  478  VGHRCIGARVNGRLVALERKLENGEFVEIFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  537

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALE GKDAMAREVRRGGLPLQRLVNGESMAAVARELHY DVSALYTAIGEGHV
Sbjct  538  AKERREEALEAGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYIDVSALYTAIGEGHV  597

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660
            SA+HVVQRLLAELGGIDQAEEELAERSTP TM RR RSTDDVGVSVPGAPGVLTKLAKCC
Sbjct  598  SARHVVQRLLAELGGIDQAEEELAERSTPTTMLRRQRSTDDVGVSVPGAPGVLTKLAKCC  657

Query  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720
            TPVPGD IMGFVTRGGGVSVHRTDCTN ASLQQQAERIIEVLWAPS SSVFLVAIQVEAL
Sbjct  658  TPVPGDAIMGFVTRGGGVSVHRTDCTNTASLQQQAERIIEVLWAPSSSSVFLVAIQVEAL  717

Query  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780
            DRHRLL D+TRALADE+V+ILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN VRNVEGV
Sbjct  718  DRHRLLLDITRALADERVDILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGV  777

Query  781  YDVYRVTSAA  790
            YDVYRV SA+
Sbjct  778  YDVYRVMSAS  787


>gi|118467123|ref|YP_882646.1| GTP pyrophosphokinase [Mycobacterium avium 104]
 gi|118168410|gb|ABK69307.1| GTP pyrophosphokinase [Mycobacterium avium 104]
Length=791

 Score = 1483 bits (3840),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 736/790 (94%), Positives = 757/790 (96%), Gaps = 2/790 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            VAE+   AQA+  P E+     P +ETPE P E+LKTS SASRRVRARLARRMTAQRST 
Sbjct  4    VAEENSAAQALDAPAESPP--NPVIETPEPPTESLKTSSSASRRVRARLARRMTAQRSTL  61

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            NPVLEPLVA+HREIYPKA++ +LQRA+EVADQRHASQLR SGDPYITHPLAVA ILAELG
Sbjct  62   NPVLEPLVAMHREIYPKANVQLLQRAFEVADQRHASQLRHSGDPYITHPLAVATILAELG  121

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MD+TTLVAALLHDTVEDTGYTL  L+EEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  122  MDSTTLVAALLHDTVEDTGYTLAQLSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  181

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  182  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  241

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKY+EIVRLVAGRAPSRDTYLAKVRAEI+NTL ASKIKATVEGRPKHYWS
Sbjct  242  EDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIINTLNASKIKATVEGRPKHYWS  301

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFDDIHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  302  IYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  361

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGV HPHAAAEIDDM
Sbjct  362  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDM  421

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTP+DFAYAVHTE
Sbjct  422  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPIDFAYAVHTE  481

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGEVVEVFTSKA NAGPSRDWQQFVVSPRAK KIRQWF
Sbjct  482  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQQFVVSPRAKAKIRQWF  541

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALE GKDAMAREVRRGGLPLQRLVN ESM+AVARELHYADVSALYTAIGEGHV
Sbjct  542  AKERREEALEAGKDAMAREVRRGGLPLQRLVNAESMSAVARELHYADVSALYTAIGEGHV  601

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660
            SA+HVVQRLLAELGGIDQAEE+LAERSTP TM RRPRS+DDVGVSVPGAPGVLTKLAKCC
Sbjct  602  SARHVVQRLLAELGGIDQAEEDLAERSTPTTMLRRPRSSDDVGVSVPGAPGVLTKLAKCC  661

Query  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720
            TPVPGD IMGFVTRGGGVSVHRTDCTNAASLQQQ+ERIIEV WAPSPSSVFLVAIQVEAL
Sbjct  662  TPVPGDQIMGFVTRGGGVSVHRTDCTNAASLQQQSERIIEVHWAPSPSSVFLVAIQVEAL  721

Query  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780
            DRHRLLSDVTR LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN VRNVEGV
Sbjct  722  DRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGV  781

Query  781  YDVYRVTSAA  790
            YDVYRVTSAA
Sbjct  782  YDVYRVTSAA  791


>gi|336461524|gb|EGO40392.1| (p)ppGpp synthetase, RelA/SpoT family [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=788

 Score = 1483 bits (3839),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 735/790 (94%), Positives = 757/790 (96%), Gaps = 2/790 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            +AE+   AQA+  P E+     P +ETPE P E+LKTS SASRRVRARLARRMTAQRST 
Sbjct  1    MAEENSAAQALDAPAESPP--NPVIETPEPPTESLKTSSSASRRVRARLARRMTAQRSTL  58

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            NPVLEPLVA+HREIYPKA++ +LQRA+EVADQRHASQLR SGDPYITHPLAVA ILAELG
Sbjct  59   NPVLEPLVAMHREIYPKANVQLLQRAFEVADQRHASQLRHSGDPYITHPLAVATILAELG  118

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MDTTTLVAALLHDTVEDTGYTL  L+EEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  119  MDTTTLVAALLHDTVEDTGYTLAQLSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  178

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  179  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  238

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKY+EIVRLVAGRAPSRDTYLAKVRAEI+NTL ASKIKATVEGRPKHYWS
Sbjct  239  EDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIINTLNASKIKATVEGRPKHYWS  298

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFD+IHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  299  IYQKMIVKGRDFDNIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  358

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGV HPHAAAEIDDM
Sbjct  359  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDM  418

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTP+DFAYAVHTE
Sbjct  419  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPIDFAYAVHTE  478

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGEVVEVFTSKA NAGPSRDWQQFVVSPRAK KIRQWF
Sbjct  479  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQQFVVSPRAKAKIRQWF  538

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALE GKDAMAREVRRGGLPLQRLVN ESM+AVARELHYADVSALYTAIGEGHV
Sbjct  539  AKERREEALEAGKDAMAREVRRGGLPLQRLVNAESMSAVARELHYADVSALYTAIGEGHV  598

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660
            SA+HVVQRLLAELGGIDQAEE+LAERSTP TM RRPRS+DDVGVSVPGAPGVLTKLAKCC
Sbjct  599  SARHVVQRLLAELGGIDQAEEDLAERSTPTTMLRRPRSSDDVGVSVPGAPGVLTKLAKCC  658

Query  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720
            TPVPGD IMGFVTRGGGVSVHRTDCTNAASLQQQ+ERIIEV WAPSPSSVFLVAIQVEAL
Sbjct  659  TPVPGDQIMGFVTRGGGVSVHRTDCTNAASLQQQSERIIEVHWAPSPSSVFLVAIQVEAL  718

Query  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780
            DRHRLLSDVTR LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN VRNVEGV
Sbjct  719  DRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGV  778

Query  781  YDVYRVTSAA  790
            YDVYRVTSAA
Sbjct  779  YDVYRVTSAA  788


>gi|41407145|ref|NP_959981.1| RelA [Mycobacterium avium subsp. paratuberculosis K-10]
 gi|41395496|gb|AAS03364.1| RelA [Mycobacterium avium subsp. paratuberculosis K-10]
Length=788

 Score = 1483 bits (3838),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 735/790 (94%), Positives = 756/790 (96%), Gaps = 2/790 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            +AE+   AQA+  P E+     P +ETPE P E+LKTS SASRRVRARLARRMTAQRST 
Sbjct  1    MAEENSAAQALDAPAESPP--NPVIETPEPPTESLKTSSSASRRVRARLARRMTAQRSTL  58

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            NPVLEPLVA+HREIYPKA++ +LQRA+EVADQRHASQLR SGDPYITHPLAVA ILAELG
Sbjct  59   NPVLEPLVAMHREIYPKANVQLLQRAFEVADQRHASQLRHSGDPYITHPLAVATILAELG  118

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MDTTTLVAALLHDTVEDTGYTL  L+EEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  119  MDTTTLVAALLHDTVEDTGYTLAQLSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  178

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  179  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  238

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKY+EIVRLVAGRAPSRDTYLAKVRAEI+NTL ASKIKATVEGRPKHYWS
Sbjct  239  EDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIINTLNASKIKATVEGRPKHYWS  298

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFDDIHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  299  IYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  358

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGV HPHAAAEIDDM
Sbjct  359  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDM  418

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTP+DFAYAVHTE
Sbjct  419  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPIDFAYAVHTE  478

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGEVVEVFTSKA NAGPSRDWQQFVVSPRAK KIRQWF
Sbjct  479  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQQFVVSPRAKAKIRQWF  538

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALE GKDAMAREVRRGGLPLQRLVN ESM+AVARELHYADVSALYTAIGEGHV
Sbjct  539  AKERREEALEAGKDAMAREVRRGGLPLQRLVNAESMSAVARELHYADVSALYTAIGEGHV  598

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660
            SA+HVVQRLLAELGGIDQ EE+LAERSTP TM RRPRS+DDVGVSVPGAPGVLTKLAKCC
Sbjct  599  SARHVVQRLLAELGGIDQTEEDLAERSTPTTMLRRPRSSDDVGVSVPGAPGVLTKLAKCC  658

Query  661  TPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEAL  720
            TPVPGD IMGFVTRGGGVSVHRTDCTNAASLQQQ+ERIIEV WAPSPSSVFLVAIQVEAL
Sbjct  659  TPVPGDQIMGFVTRGGGVSVHRTDCTNAASLQQQSERIIEVHWAPSPSSVFLVAIQVEAL  718

Query  721  DRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGV  780
            DRHRLLSDVTR LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN VRNVEGV
Sbjct  719  DRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGV  778

Query  781  YDVYRVTSAA  790
            YDVYRVTSAA
Sbjct  779  YDVYRVTSAA  788


>gi|183982138|ref|YP_001850429.1| GTP pyrophosphokinase RelA [Mycobacterium marinum M]
 gi|183175464|gb|ACC40574.1| GTP pyrophosphokinase RelA [Mycobacterium marinum M]
Length=787

 Score = 1480 bits (3832),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 733/791 (93%), Positives = 759/791 (96%), Gaps = 5/791 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPES-PVETLKTSISASRRVRARLARRMTAQRST  59
            +A+DQ T QAV P  E+     P +E PE+ P ETLKT+ SASRRVRARLARR+TAQRS 
Sbjct  1    MADDQSTTQAVVPSVESP----PVVEAPEAAPAETLKTTSSASRRVRARLARRITAQRSA  56

Query  60   TNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAEL  119
             NPVLEPLVAVHRE+YPKADLS+LQRAYEVADQRHA Q R SGDPYITHPLAVANILAEL
Sbjct  57   INPVLEPLVAVHREVYPKADLSLLQRAYEVADQRHAGQFRHSGDPYITHPLAVANILAEL  116

Query  120  GMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRK  179
            GMD+TTLVAALLHDTVEDTGYTLEAL+EEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRK
Sbjct  117  GMDSTTLVAALLHDTVEDTGYTLEALSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRK  176

Query  180  MITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWE  239
            MITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWE
Sbjct  177  MITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWE  236

Query  240  LEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYW  299
            LEDLSFAILHPKKY+EIVRLVAGRAPSRDTYLAKVRAEI+ TL+ASKIKATVEGRPKHYW
Sbjct  237  LEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIIATLSASKIKATVEGRPKHYW  296

Query  300  SIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYG  359
            SIYQKMIVKGRDFDDIHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYG
Sbjct  297  SIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYG  356

Query  360  VYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDD  419
            VYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGV HPHAAAEIDD
Sbjct  357  VYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDD  416

Query  420  MAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHT  479
            MAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHT
Sbjct  417  MAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHT  476

Query  480  EVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQW  539
            EVGHRCIGARVNGRLVALER+LENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQW
Sbjct  477  EVGHRCIGARVNGRLVALERQLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQW  536

Query  540  FAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGH  599
            FAKERREEALE GK+A+AREVRRGGLPLQRLVNGESM AVARELHY DVSALYTAIGEGH
Sbjct  537  FAKERREEALEAGKEAIAREVRRGGLPLQRLVNGESMGAVARELHYTDVSALYTAIGEGH  596

Query  600  VSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKC  659
            VSA+H +QRLLAELGGIDQAEEELAER+TP T+PRRPRS+DDVGVSVPGAPGV+TKLAKC
Sbjct  597  VSARHAMQRLLAELGGIDQAEEELAERATPTTIPRRPRSSDDVGVSVPGAPGVMTKLAKC  656

Query  660  CTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEA  719
            CTPVPGD IMGFVTRGGGVSVHRTDCTNA SL+QQ+ERIIEV WAPSPSSVFLVAIQVEA
Sbjct  657  CTPVPGDNIMGFVTRGGGVSVHRTDCTNAESLKQQSERIIEVHWAPSPSSVFLVAIQVEA  716

Query  720  LDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEG  779
            LDRHRLLSDVTR LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN VRNVEG
Sbjct  717  LDRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEG  776

Query  780  VYDVYRVTSAA  790
            VYDVYRVTSAA
Sbjct  777  VYDVYRVTSAA  787


>gi|254820460|ref|ZP_05225461.1| GTP pyrophosphokinase [Mycobacterium intracellulare ATCC 13950]
Length=792

 Score = 1477 bits (3824),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 735/792 (93%), Positives = 760/792 (96%), Gaps = 2/792 (0%)

Query  1    VAEDQLTAQAVAPPTEAS--AALEPALETPESPVETLKTSISASRRVRARLARRMTAQRS  58
            +A+D   +QA+  PT+ +   A+   +E PE P E+LKTS SASRRVRARLARRMTAQRS
Sbjct  1    MADDNSASQALDAPTKVTEPPAITQPMEAPEPPTESLKTSSSASRRVRARLARRMTAQRS  60

Query  59   TTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAE  118
            T NPVLEPLVAVHREIYPKA++S+LQRA+EVADQRHA+QLR SGDPYITHPLAVA ILAE
Sbjct  61   TLNPVLEPLVAVHREIYPKANVSMLQRAFEVADQRHATQLRHSGDPYITHPLAVATILAE  120

Query  119  LGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIR  178
            LGMDTTTLVAALLHDTVEDTGYTL+AL+EEFGEEVGHLVDGVTKLDRVVLGSAAEGETIR
Sbjct  121  LGMDTTTLVAALLHDTVEDTGYTLDALSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIR  180

Query  179  KMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKW  238
            KMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKW
Sbjct  181  KMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKW  240

Query  239  ELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHY  298
            ELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIV+TL ASKIKATVEGRPKHY
Sbjct  241  ELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVSTLGASKIKATVEGRPKHY  300

Query  299  WSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRY  358
            WSIYQKMIVKGRDFDDIHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRY
Sbjct  301  WSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRY  360

Query  359  GVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEID  418
            GVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGV HPHAAAEID
Sbjct  361  GVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAAAEID  420

Query  419  DMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVH  478
            DMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVH
Sbjct  421  DMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVH  480

Query  479  TEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQ  538
            TEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKA  AGPSRDWQQFVVSPRAK KIRQ
Sbjct  481  TEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAATAGPSRDWQQFVVSPRAKAKIRQ  540

Query  539  WFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEG  598
            WFAKERREEALE GKDAMAREVRRGGLPLQRLVNGE+++AVARELHY DVSALYTAIGEG
Sbjct  541  WFAKERREEALEAGKDAMAREVRRGGLPLQRLVNGETLSAVARELHYLDVSALYTAIGEG  600

Query  599  HVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAK  658
            HVSA+HVVQRLLAELGGIDQAEE+LAERSTP TM RRPRS+DDVGVSVPGAPGVLTKLAK
Sbjct  601  HVSARHVVQRLLAELGGIDQAEEDLAERSTPTTMLRRPRSSDDVGVSVPGAPGVLTKLAK  660

Query  659  CCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVE  718
            CCTPVPGD IMGFVTRGGGVSVHRTDCTNAASLQQQ+ERIIEV WAPSPSSVFLVAIQVE
Sbjct  661  CCTPVPGDQIMGFVTRGGGVSVHRTDCTNAASLQQQSERIIEVHWAPSPSSVFLVAIQVE  720

Query  719  ALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVE  778
            ALDRHRLLSDVTR LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN VRNVE
Sbjct  721  ALDRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVE  780

Query  779  GVYDVYRVTSAA  790
            GVYDVYRVTSAA
Sbjct  781  GVYDVYRVTSAA  792


>gi|118617353|ref|YP_905685.1| GTP pyrophosphokinase RelA [Mycobacterium ulcerans Agy99]
 gi|118569463|gb|ABL04214.1| GTP pyrophosphokinase RelA [Mycobacterium ulcerans Agy99]
Length=790

 Score = 1476 bits (3822),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 731/791 (93%), Positives = 759/791 (96%), Gaps = 5/791 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPES-PVETLKTSISASRRVRARLARRMTAQRST  59
            VA+DQ T QAV P  E+     P +E PE+ P ETLKT+ SASRRVRARLARR+TAQRS 
Sbjct  4    VADDQSTTQAVVPSVESP----PVVEAPEAAPAETLKTTSSASRRVRARLARRITAQRSA  59

Query  60   TNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAEL  119
             NPVLEPLVAVHRE+YPKADLS+LQRAYEVADQRHA Q R SGDPYITHPLAVANILAEL
Sbjct  60   INPVLEPLVAVHREVYPKADLSLLQRAYEVADQRHAGQFRHSGDPYITHPLAVANILAEL  119

Query  120  GMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRK  179
            GMD+TTLVAALLHDTVEDTGYTLEAL+EEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRK
Sbjct  120  GMDSTTLVAALLHDTVEDTGYTLEALSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRK  179

Query  180  MITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWE  239
            MITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWE
Sbjct  180  MITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWE  239

Query  240  LEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYW  299
            LEDLSFAILHPKKY+EIVRLVAGRAPSRDTYLAKVRAEI+ TL+ASKIKATVEGRPKHYW
Sbjct  240  LEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIIATLSASKIKATVEGRPKHYW  299

Query  300  SIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYG  359
            SIYQKMIVKGRDFDDIHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYG
Sbjct  300  SIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYG  359

Query  360  VYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDD  419
            VY+SLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGV HPHAAAEIDD
Sbjct  360  VYESLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDD  419

Query  420  MAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHT  479
            MAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHT
Sbjct  420  MAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHT  479

Query  480  EVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQW  539
            EVGHRCIGARVNGRLVALER+LENGEVV+VFTSKAPNAGPSRDWQQFVVSPRA+TKIRQW
Sbjct  480  EVGHRCIGARVNGRLVALERQLENGEVVDVFTSKAPNAGPSRDWQQFVVSPRAETKIRQW  539

Query  540  FAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGH  599
            FAKERREEALE GK+A+AREVRRGGLPLQRLVNGESM AVARELHY DVSALYTAIGEGH
Sbjct  540  FAKERREEALEAGKEAIAREVRRGGLPLQRLVNGESMGAVARELHYTDVSALYTAIGEGH  599

Query  600  VSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKC  659
            VSA+H +QRLLAELGGIDQAEEELAER+TP T+PRRPRS+DDVGVSVPGAPGV+TKLAKC
Sbjct  600  VSARHAMQRLLAELGGIDQAEEELAERATPTTIPRRPRSSDDVGVSVPGAPGVMTKLAKC  659

Query  660  CTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEA  719
            CTPVPGD IMGFVTRGGGVSVHRTDCTNA SL+QQ+ERIIEV WAPSPSSVFLVAIQVEA
Sbjct  660  CTPVPGDNIMGFVTRGGGVSVHRTDCTNAESLKQQSERIIEVHWAPSPSSVFLVAIQVEA  719

Query  720  LDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEG  779
            LDRHRLLSDVTR LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN VRNVEG
Sbjct  720  LDRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEG  779

Query  780  VYDVYRVTSAA  790
            VYDVYRVTSAA
Sbjct  780  VYDVYRVTSAA  790


>gi|296170827|ref|ZP_06852392.1| GTP diphosphokinase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295894516|gb|EFG74256.1| GTP diphosphokinase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=799

 Score = 1472 bits (3812),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 732/796 (92%), Positives = 758/796 (96%), Gaps = 6/796 (0%)

Query  1    VAEDQLTAQAVAPPTEASAAL---EPAL---ETPESPVETLKTSISASRRVRARLARRMT  54
            VA+D+  AQA+  P + + AL   EP     + PE P ETLKT  SASRRVRARLARRMT
Sbjct  4    VADDKSAAQALDAPGDVADALLVGEPVTAQADPPEPPTETLKTPSSASRRVRARLARRMT  63

Query  55   AQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVAN  114
            AQR+  NPVLEPLVAVHREIYPKA+LS+LQRA+EVADQRHA+QLR SGDPYITHPLAVAN
Sbjct  64   AQRNALNPVLEPLVAVHREIYPKANLSLLQRAFEVADQRHATQLRHSGDPYITHPLAVAN  123

Query  115  ILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEG  174
            ILAELGMDTTTLVAALLHDT+EDTGYTLE ++EEFG+EV HLVDGVTKLDRVVLG+AAEG
Sbjct  124  ILAELGMDTTTLVAALLHDTIEDTGYTLEQMSEEFGDEVAHLVDGVTKLDRVVLGTAAEG  183

Query  175  ETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMA  234
            ETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMA
Sbjct  184  ETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMA  243

Query  235  SVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGR  294
            SVKWELEDLSFAILHPKKY+EIVRLVAGRAPSRDTYLAKVRAEI+NTL ASKIKATVEGR
Sbjct  244  SVKWELEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIINTLNASKIKATVEGR  303

Query  295  PKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIA  354
            PKHYWSIYQKMIVKGRDFDDIHDLVG+RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIA
Sbjct  304  PKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIA  363

Query  355  QPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAA  414
            QPRYGVYQSLHTTVVGPEGKPLE+QIRTRDMHRTAEYGIAAHWRYKEAKGRNGV HPHA 
Sbjct  364  QPRYGVYQSLHTTVVGPEGKPLEIQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAT  423

Query  415  AEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFA  474
            AEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLP GSTPVDFA
Sbjct  424  AEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPNGSTPVDFA  483

Query  475  YAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKT  534
            YAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKA NAGPSRDWQQFVVSPRAK 
Sbjct  484  YAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKALNAGPSRDWQQFVVSPRAKA  543

Query  535  KIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTA  594
            KIRQWFAKERREEALE GK+AMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTA
Sbjct  544  KIRQWFAKERREEALEAGKEAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTA  603

Query  595  IGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLT  654
            IGEGHVSAKHVVQRLLAELGGIDQAEE+LAERSTP TM RRPRS+DDVGVSVPGAPGVL+
Sbjct  604  IGEGHVSAKHVVQRLLAELGGIDQAEEDLAERSTPTTMLRRPRSSDDVGVSVPGAPGVLS  663

Query  655  KLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVA  714
            KLAKCCTPVPGD IMGFVTRGGGVSVHRTDCTNAASLQQQ+ERIIEV WAPSPSSVFLVA
Sbjct  664  KLAKCCTPVPGDQIMGFVTRGGGVSVHRTDCTNAASLQQQSERIIEVHWAPSPSSVFLVA  723

Query  715  IQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAV  774
            IQVEALDRHRLLSDVTR LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN V
Sbjct  724  IQVEALDRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVV  783

Query  775  RNVEGVYDVYRVTSAA  790
            RNVEGV+DVYRVTSAA
Sbjct  784  RNVEGVFDVYRVTSAA  799


>gi|120403572|ref|YP_953401.1| (p)ppGpp synthetase I SpoT/RelA [Mycobacterium vanbaalenii PYR-1]
 gi|119956390|gb|ABM13395.1| (p)ppGpp synthetase I, SpoT/RelA [Mycobacterium vanbaalenii PYR-1]
Length=788

 Score = 1407 bits (3642),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 694/769 (91%), Positives = 731/769 (96%), Gaps = 1/769 (0%)

Query  23   PALETPES-PVETLKTSISASRRVRARLARRMTAQRSTTNPVLEPLVAVHREIYPKADLS  81
            P + TPE+ P+E  K   SASRRVRARLARRMT+QRST NPVLEPLVAVHREIYPKADL+
Sbjct  20   PPVATPETQPMELPKPPTSASRRVRARLARRMTSQRSTINPVLEPLVAVHREIYPKADLT  79

Query  82   ILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVEDTGYT  141
            +LQ+AYEVA+QRHA QLR+SGDPYITHPLAVANILAELGMDTTTL+AALLHDTVEDTGYT
Sbjct  80   LLQKAYEVAEQRHADQLRKSGDPYITHPLAVANILAELGMDTTTLIAALLHDTVEDTGYT  139

Query  142  LEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDPRVLVIKVADRLHN  201
            LEALT+EFG EVGHLVDGVTKLD+V LG+AAEGETIRKMI AMARDPRVLVIKVADRLHN
Sbjct  140  LEALTQEFGTEVGHLVDGVTKLDKVALGTAAEGETIRKMIIAMARDPRVLVIKVADRLHN  199

Query  202  MRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELEDLSFAILHPKKYEEIVRLVA  261
            MRTMRFLPPEKQARKARETLEVIAPLAHRLGMA+VKWELEDLSFAILHPKKYEEIVRLVA
Sbjct  200  MRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELEDLSFAILHPKKYEEIVRLVA  259

Query  262  GRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGV  321
             RAPSRDTYLAKVRAEI  TL ASKI ATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGV
Sbjct  260  DRAPSRDTYLAKVRAEITATLNASKINATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGV  319

Query  322  RILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIR  381
            RILCDE+RDCYAAVGVVHSLWQP+AGRFKDYIAQPR+GVYQSLHTTVVGPEGKPLEVQIR
Sbjct  320  RILCDEVRDCYAAVGVVHSLWQPIAGRFKDYIAQPRFGVYQSLHTTVVGPEGKPLEVQIR  379

Query  382  TRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQREAADPGEFLE  441
            T DMH+TAEYGIAAHWRYKEAKGRNGV   HAA EIDDMAWMRQLLDWQREAADPGEFLE
Sbjct  380  TIDMHKTAEYGIAAHWRYKEAKGRNGVPPSHAATEIDDMAWMRQLLDWQREAADPGEFLE  439

Query  442  SLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKL  501
            SLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKL
Sbjct  440  SLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKL  499

Query  502  ENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWFAKERREEALETGKDAMAREVR  561
            ENGEVVEVFTSKAPNAGPSRDWQ FVVSPRAK KIRQWFAKERREEAL++GK+A+AREVR
Sbjct  500  ENGEVVEVFTSKAPNAGPSRDWQTFVVSPRAKAKIRQWFAKERREEALDSGKEAIAREVR  559

Query  562  RGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEE  621
            RGGLPLQRL+N E+MAA+AREL YADVSALYTA+GEGHVSA+HVVQRL+A+LGG D+A +
Sbjct  560  RGGLPLQRLMNAETMAALARELRYADVSALYTAVGEGHVSARHVVQRLVAQLGGDDEAAD  619

Query  622  ELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVH  681
            E+AERSTPATMP R R++DDVGV+VPGAPGVL KLAKCCTPVPGD IMGFVTRGGGVSVH
Sbjct  620  EIAERSTPATMPVRQRTSDDVGVAVPGAPGVLCKLAKCCTPVPGDNIMGFVTRGGGVSVH  679

Query  682  RTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRHRLLSDVTRALADEKVNIL  741
            RTDCTNAASLQ Q+ERIIEV WAPSPSSVFLVAIQVEALDRHRLLSDVTR LADEKVNIL
Sbjct  680  RTDCTNAASLQDQSERIIEVQWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADEKVNIL  739

Query  742  SASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDVYRVTSAA  790
            SASVTTS DRVAISRFTFEMGDPKHLGH+LN VRNVEGVYDVYRVTSAA
Sbjct  740  SASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRVTSAA  788


>gi|108799247|ref|YP_639444.1| (p)ppGpp synthetase I SpoT/RelA [Mycobacterium sp. MCS]
 gi|119868363|ref|YP_938315.1| (p)ppGpp synthetase I SpoT/RelA [Mycobacterium sp. KMS]
 gi|108769666|gb|ABG08388.1| (p)ppGpp synthetase I, SpoT/RelA [Mycobacterium sp. MCS]
 gi|119694452|gb|ABL91525.1| (p)ppGpp synthetase I, SpoT/RelA [Mycobacterium sp. KMS]
Length=801

 Score = 1405 bits (3638),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 698/777 (90%), Positives = 726/777 (94%), Gaps = 0/777 (0%)

Query  14   PTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTTNPVLEPLVAVHRE  73
            P +  A+   A +T  S  E  KTS SASRRVRARLARRMTAQRST NPVLEPLVAVHRE
Sbjct  25   PPKGDASKGDASKTDASKTEAPKTSSSASRRVRARLARRMTAQRSTVNPVLEPLVAVHRE  84

Query  74   IYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVAALLHD  133
             YPKADL++LQRAYEVA++RHA Q+R+SGDPYITHPLAVANILAELGMDTTTL+AALLHD
Sbjct  85   FYPKADLTLLQRAYEVAEERHADQMRRSGDPYITHPLAVANILAELGMDTTTLIAALLHD  144

Query  134  TVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDPRVLVI  193
            TVEDTGYTL+ALT EFG EVGHLVDGVTKLD+V LG+AAEGETIRKMI AMARDPRVLVI
Sbjct  145  TVEDTGYTLDALTAEFGAEVGHLVDGVTKLDKVALGTAAEGETIRKMIIAMARDPRVLVI  204

Query  194  KVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELEDLSFAILHPKKY  253
            KVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMA+VKWELEDLSFAILHPKKY
Sbjct  205  KVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELEDLSFAILHPKKY  264

Query  254  EEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWSIYQKMIVKGRDFD  313
            +EIVRLVA RAPSRDTYLAKVRAEIVNTLT SKI ATVEGRPKHYWSIYQKMIVKGRDFD
Sbjct  265  DEIVRLVADRAPSRDTYLAKVRAEIVNTLTKSKINATVEGRPKHYWSIYQKMIVKGRDFD  324

Query  314  DIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEG  373
            DIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEG
Sbjct  325  DIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEG  384

Query  374  KPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQREA  433
            KPLEVQIRTRDMHRTAEYGIAAHWRYKE+KGRNG    H AAEIDDMAWMRQLLDWQREA
Sbjct  385  KPLEVQIRTRDMHRTAEYGIAAHWRYKESKGRNGSPAGHTAAEIDDMAWMRQLLDWQREA  444

Query  434  ADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCIGARVNGR  493
            ADPGEFLESLRYDLAVQEIFVFTPKGDVITLP GSTPVDFAYAVHTEVGHRCIGARVNGR
Sbjct  445  ADPGEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVGHRCIGARVNGR  504

Query  494  LVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWFAKERREEALETGK  553
            LVALERKLENGEVVE+FTSKA  AGPSRDWQ FVVSPRAK KIRQWFAKERREEALE GK
Sbjct  505  LVALERKLENGEVVEIFTSKAQGAGPSRDWQSFVVSPRAKAKIRQWFAKERREEALEAGK  564

Query  554  DAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHVSAKHVVQRLLAEL  613
            DA+ REVRRGGLPLQRL+N ESMA++AREL YADVSALYTA+GEGH+SA+HVVQRLLA  
Sbjct  565  DAIGREVRRGGLPLQRLMNAESMASLARELRYADVSALYTAVGEGHISARHVVQRLLAVF  624

Query  614  GGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFVT  673
            GG D AE+ELAERSTPATMP R RSTDD GVSVPGAPGVLTKLAKCCTPVPGD IMGFVT
Sbjct  625  GGDDAAEDELAERSTPATMPVRQRSTDDTGVSVPGAPGVLTKLAKCCTPVPGDQIMGFVT  684

Query  674  RGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRHRLLSDVTRAL  733
            RGGGVSVHRTDCTNA+SLQ+QAERIIEV WAPSPSSVFLVAIQVEALDRHRLLSDVTR L
Sbjct  685  RGGGVSVHRTDCTNASSLQEQAERIIEVEWAPSPSSVFLVAIQVEALDRHRLLSDVTRVL  744

Query  734  ADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDVYRVTSAA  790
            ADEKVNILSASVTTS DRVAISRFTFEMGDPKHLG+LL  VRNVEGVYDVYRVTSAA
Sbjct  745  ADEKVNILSASVTTSNDRVAISRFTFEMGDPKHLGYLLRVVRNVEGVYDVYRVTSAA  801


>gi|126434905|ref|YP_001070596.1| (p)ppGpp synthetase I SpoT/RelA [Mycobacterium sp. JLS]
 gi|126234705|gb|ABN98105.1| (p)ppGpp synthetase I, SpoT/RelA [Mycobacterium sp. JLS]
Length=806

 Score = 1404 bits (3635),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 697/776 (90%), Positives = 726/776 (94%), Gaps = 0/776 (0%)

Query  15   TEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTTNPVLEPLVAVHREI  74
            ++  A+   A +T  S  E  KTS SASRRVRARLARRMTAQRST NPVLEPLVAVHRE 
Sbjct  31   SKTDASKTDASKTDASKTEAPKTSSSASRRVRARLARRMTAQRSTVNPVLEPLVAVHREF  90

Query  75   YPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVAALLHDT  134
            YPKADL++LQRAYEVA++RHA Q+R+SGDPYITHPLAVANILAELGMDTTTL+AALLHDT
Sbjct  91   YPKADLTLLQRAYEVAEERHADQMRRSGDPYITHPLAVANILAELGMDTTTLIAALLHDT  150

Query  135  VEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDPRVLVIK  194
            VEDTGYTL+ALT EFG EVGHLVDGVTKLD+V LG+AAEGETIRKMI AMARDPRVLVIK
Sbjct  151  VEDTGYTLDALTAEFGAEVGHLVDGVTKLDKVALGTAAEGETIRKMIIAMARDPRVLVIK  210

Query  195  VADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELEDLSFAILHPKKYE  254
            VADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMA+VKWELEDLSFAILHPKKY+
Sbjct  211  VADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELEDLSFAILHPKKYD  270

Query  255  EIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWSIYQKMIVKGRDFDD  314
            EIVRLVA RAPSRDTYLAKVRAEIVNTLT SKI ATVEGRPKHYWSIYQKMIVKGRDFDD
Sbjct  271  EIVRLVADRAPSRDTYLAKVRAEIVNTLTKSKINATVEGRPKHYWSIYQKMIVKGRDFDD  330

Query  315  IHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGK  374
            IHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGK
Sbjct  331  IHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGK  390

Query  375  PLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQREAA  434
            PLEVQIRTRDMHRTAEYGIAAHWRYKE+KGRNG    H AAEIDDMAWMRQLLDWQREAA
Sbjct  391  PLEVQIRTRDMHRTAEYGIAAHWRYKESKGRNGSPAGHTAAEIDDMAWMRQLLDWQREAA  450

Query  435  DPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCIGARVNGRL  494
            DPGEFLESLRYDLAVQEIFVFTPKGDVITLP GSTPVDFAYAVHTEVGHRCIGARVNGRL
Sbjct  451  DPGEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVGHRCIGARVNGRL  510

Query  495  VALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWFAKERREEALETGKD  554
            VALERKLENGEVVE+FTSKA  AGPSRDWQ FVVSPRAK KIRQWFAKERREEALE GKD
Sbjct  511  VALERKLENGEVVEIFTSKAQGAGPSRDWQSFVVSPRAKAKIRQWFAKERREEALEAGKD  570

Query  555  AMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHVSAKHVVQRLLAELG  614
            A+ REVRRGGLPLQRL+N ESMA++AREL YADVSALYTA+GEGH+SA+HVVQRLLA  G
Sbjct  571  AIGREVRRGGLPLQRLMNAESMASLARELRYADVSALYTAVGEGHISARHVVQRLLAVFG  630

Query  615  GIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFVTR  674
            G D AE+ELAERSTPATMP R RSTDD GVSVPGAPGVLTKLAKCCTPVPGD IMGFVTR
Sbjct  631  GDDAAEDELAERSTPATMPVRQRSTDDTGVSVPGAPGVLTKLAKCCTPVPGDQIMGFVTR  690

Query  675  GGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRHRLLSDVTRALA  734
            GGGVSVHRTDCTNA+SLQ+QAERIIEV WAPSPSSVFLVAIQVEALDRHRLLSDVTR LA
Sbjct  691  GGGVSVHRTDCTNASSLQEQAERIIEVEWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLA  750

Query  735  DEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDVYRVTSAA  790
            DEKVNILSASVTTS DRVAISRFTFEMGDPKHLG+LL  VRNVEGVYDVYRVTSAA
Sbjct  751  DEKVNILSASVTTSNDRVAISRFTFEMGDPKHLGYLLRVVRNVEGVYDVYRVTSAA  806


>gi|118471771|ref|YP_887284.1| GTP pyrophosphokinase [Mycobacterium smegmatis str. MC2 155]
 gi|118173058|gb|ABK73954.1| GTP pyrophosphokinase [Mycobacterium smegmatis str. MC2 155]
Length=797

 Score = 1404 bits (3633),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 679/738 (93%), Positives = 702/738 (96%), Gaps = 0/738 (0%)

Query  53   MTAQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAV  112
            MTAQRS  NPVLEPLVAVHREIYPKADL +LQRAYEVA++RHA QLR+SGDPYITHPLAV
Sbjct  60   MTAQRSAINPVLEPLVAVHREIYPKADLQLLQRAYEVAEKRHADQLRKSGDPYITHPLAV  119

Query  113  ANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAA  172
            ANILAELGMDTTTLVAALLHDTVEDTGY+LEALT +FG EVGHLVDGVTKLD+VVLGSAA
Sbjct  120  ANILAELGMDTTTLVAALLHDTVEDTGYSLEALTADFGSEVGHLVDGVTKLDKVVLGSAA  179

Query  173  EGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG  232
            EGETIRKMI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG
Sbjct  180  EGETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG  239

Query  233  MASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVE  292
            MA+VKWELEDL+FAILHPKKYEEIVRLVA RAPSRDTYLAKVRAEI   L+A KI A VE
Sbjct  240  MATVKWELEDLAFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEIGVALSAMKINAVVE  299

Query  293  GRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDY  352
            GRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDY
Sbjct  300  GRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDY  359

Query  353  IAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPH  412
            IAQPRYGVYQSLHTTVVGPEGKPLEVQIRTR+MHRTAEYGIAAHWRYKEAKGRNGV H H
Sbjct  360  IAQPRYGVYQSLHTTVVGPEGKPLEVQIRTREMHRTAEYGIAAHWRYKEAKGRNGVPHSH  419

Query  413  AAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVD  472
            AAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLA QEIFVFTPKGDVITLP GSTPVD
Sbjct  420  AAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLATQEIFVFTPKGDVITLPAGSTPVD  479

Query  473  FAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRA  532
            FAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQ FVVSPRA
Sbjct  480  FAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQGFVVSPRA  539

Query  533  KTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALY  592
            KTKIRQWFAKERREEALE+GKDA+AREVRRGGLPLQRL+N E+M A+AREL Y DVSALY
Sbjct  540  KTKIRQWFAKERREEALESGKDAIAREVRRGGLPLQRLMNAETMGALARELRYQDVSALY  599

Query  593  TAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGV  652
            TA+GEGHVSA+HVVQRLLA+ GG D AE+ELAERSTPATMP R RS DD GV+VPGAPGV
Sbjct  600  TAVGEGHVSARHVVQRLLAQFGGDDAAEDELAERSTPATMPMRQRSNDDTGVAVPGAPGV  659

Query  653  LTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFL  712
            LTKLAKCCTPVPGD IMGFVTRGGGVSVHRTDCTNA SLQQQ+ERIIEV WAPSPSSVFL
Sbjct  660  LTKLAKCCTPVPGDTIMGFVTRGGGVSVHRTDCTNAESLQQQSERIIEVNWAPSPSSVFL  719

Query  713  VAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN  772
            VAIQVEALDRHRLLSDVTR LADEKVNILSASVTTS DRVAISRFTFEMGDPKHLGHLL+
Sbjct  720  VAIQVEALDRHRLLSDVTRVLADEKVNILSASVTTSNDRVAISRFTFEMGDPKHLGHLLS  779

Query  773  AVRNVEGVYDVYRVTSAA  790
             VRNVEGVYDVYRVTSAA
Sbjct  780  VVRNVEGVYDVYRVTSAA  797


>gi|145224394|ref|YP_001135072.1| (p)ppGpp synthetase I SpoT/RelA [Mycobacterium gilvum PYR-GCK]
 gi|315444726|ref|YP_004077605.1| (p)ppGpp synthetase, RelA/SpoT family [Mycobacterium sp. Spyr1]
 gi|145216880|gb|ABP46284.1| (p)ppGpp synthetase I, SpoT/RelA [Mycobacterium gilvum PYR-GCK]
 gi|315263029|gb|ADT99770.1| (p)ppGpp synthetase, RelA/SpoT family [Mycobacterium sp. Spyr1]
Length=790

 Score = 1397 bits (3615),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 697/792 (89%), Positives = 741/792 (94%), Gaps = 8/792 (1%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPES-PVETLKTS-ISASRRVRARLARRMTAQRS  58
            V  D  + QAV  P  A++A      +PE+ P+E +K +  SASRRVRARLARRMT+QRS
Sbjct  5    VRTDPGSGQAVQTPPPAASA------SPETQPMEIVKPAPTSASRRVRARLARRMTSQRS  58

Query  59   TTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAE  118
            T NPVLEPLVAVHREIYPKADL++LQ+AYEVA+QRHA QLR+SGDPYITHPLAVANILAE
Sbjct  59   TVNPVLEPLVAVHREIYPKADLTLLQKAYEVAEQRHADQLRKSGDPYITHPLAVANILAE  118

Query  119  LGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIR  178
            LGMDTTTL+AALLHDTVEDTGYTLEALT+EFG EVGHLVDGVTKLD+V LG+AAEGETIR
Sbjct  119  LGMDTTTLIAALLHDTVEDTGYTLEALTQEFGVEVGHLVDGVTKLDKVALGTAAEGETIR  178

Query  179  KMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKW  238
            KMI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMA+VKW
Sbjct  179  KMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKW  238

Query  239  ELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHY  298
            ELEDLSFAILHPKKYEEIVRLVA RAPSRDTYLAKVRAEI  TL ASKIKATVEGRPKHY
Sbjct  239  ELEDLSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEITATLNASKIKATVEGRPKHY  298

Query  299  WSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRY  358
            WSIYQKMIVKGRDFDDIHDLVGVRILCDE+RDCYAAVGVVHSLWQP+AGRFKDYIAQPR+
Sbjct  299  WSIYQKMIVKGRDFDDIHDLVGVRILCDEVRDCYAAVGVVHSLWQPIAGRFKDYIAQPRF  358

Query  359  GVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEID  418
            GVYQSLHTTVVGPEGKPLEVQIRT DMH+TAEYGIAAHWRYKE KGRNGV    AA EID
Sbjct  359  GVYQSLHTTVVGPEGKPLEVQIRTIDMHKTAEYGIAAHWRYKEVKGRNGVPAGSAATEID  418

Query  419  DMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVH  478
            DMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVH
Sbjct  419  DMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVH  478

Query  479  TEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQ  538
            TEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKA NAGPSRDWQ FVVSPRAK KIRQ
Sbjct  479  TEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAQNAGPSRDWQGFVVSPRAKAKIRQ  538

Query  539  WFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEG  598
            WFAKERREEAL++GK+A+AREVRRGGLPLQRL+N E+MAA+AREL Y DVSALYTA+GEG
Sbjct  539  WFAKERREEALDSGKEAIAREVRRGGLPLQRLMNAETMAALARELRYLDVSALYTAVGEG  598

Query  599  HVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAK  658
            HVSA+HVVQRL+A+LGG D+A +ELAERSTPATMP R R++DDVGV+VPGAPGVLTKLAK
Sbjct  599  HVSARHVVQRLVAQLGGDDEAADELAERSTPATMPIRQRTSDDVGVAVPGAPGVLTKLAK  658

Query  659  CCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVE  718
            CCTPVPGD I+GFVTRGGGVSVHRTDCTNAASL+QQ+ERII+V WAPSPSSVFLVAIQVE
Sbjct  659  CCTPVPGDNILGFVTRGGGVSVHRTDCTNAASLEQQSERIIDVQWAPSPSSVFLVAIQVE  718

Query  719  ALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVE  778
            ALDRHRLLSDVTR LADEKVNILSASVTTS DRVAISRFTFEMGDPKHLGH+LN VRNVE
Sbjct  719  ALDRHRLLSDVTRVLADEKVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVE  778

Query  779  GVYDVYRVTSAA  790
            GVYDVYRVTSAA
Sbjct  779  GVYDVYRVTSAA  790


>gi|169629960|ref|YP_001703609.1| GTP pyrophosphokinase [Mycobacterium abscessus ATCC 19977]
 gi|169241927|emb|CAM62955.1| Probable GTP pyrophosphokinase [Mycobacterium abscessus]
Length=788

 Score = 1395 bits (3611),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 693/782 (89%), Positives = 727/782 (93%), Gaps = 5/782 (0%)

Query  14   PTEASAALE--PALETPESPVETLKTS---ISASRRVRARLARRMTAQRSTTNPVLEPLV  68
            P+E   A+E  PAL  P    E+L+ S   +SASRRVRARLARRMTAQR   +PVLEPL+
Sbjct  7    PSENQVAVESLPALSEPGPVTESLRVSGGTMSASRRVRARLARRMTAQRGAVSPVLEPLI  66

Query  69   AVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVA  128
            AVHRE YPKAD S+LQRAYEVA+ RHA Q R+SGDPYITHP+AVANILAELGMDTTTLVA
Sbjct  67   AVHREFYPKADRSVLQRAYEVAESRHAEQFRKSGDPYITHPVAVANILAELGMDTTTLVA  126

Query  129  ALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDP  188
            A+LHDTVEDTGY+LE LT EFG EV HLVDGVTKLD+VVLG+AAEGETIRKMI AMARDP
Sbjct  127  AILHDTVEDTGYSLEQLTAEFGTEVAHLVDGVTKLDKVVLGNAAEGETIRKMIIAMARDP  186

Query  189  RVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELEDLSFAIL  248
            RVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMA+VKWELEDLSFAIL
Sbjct  187  RVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELEDLSFAIL  246

Query  249  HPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWSIYQKMIVK  308
            HPKKYEEIVRLVA RAPSRDTYLAKVRAEIV TL +S+I ATVEGRPKHYWSIYQKMIVK
Sbjct  247  HPKKYEEIVRLVADRAPSRDTYLAKVRAEIVATLNSSRISATVEGRPKHYWSIYQKMIVK  306

Query  309  GRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTV  368
            GRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPR+GVYQSLHTTV
Sbjct  307  GRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRFGVYQSLHTTV  366

Query  369  VGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLD  428
            VGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGV   HAAAEIDDMAWMRQLLD
Sbjct  367  VGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPPTHAAAEIDDMAWMRQLLD  426

Query  429  WQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCIGA  488
            WQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLP GSTPVDFAYAVHTEVGHRCIGA
Sbjct  427  WQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPAGSTPVDFAYAVHTEVGHRCIGA  486

Query  489  RVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWFAKERREEA  548
            RVNGRLVALERKLENGEVVEVFTSKA NAGPSRDWQ FVVSPRAK KIRQWFAKERREEA
Sbjct  487  RVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQTFVVSPRAKAKIRQWFAKERREEA  546

Query  549  LETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHVSAKHVVQR  608
            LE GKDA+AREVRRGGLPLQRLVNGE MA++AREL Y D S LYTA+GEGHVSA+HVVQR
Sbjct  547  LEAGKDAIAREVRRGGLPLQRLVNGEGMASLARELRYQDTSQLYTAVGEGHVSARHVVQR  606

Query  609  LLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVI  668
            L+A+LGG+D AEEELAERSTP+TMP R R +DDVGV+VPGAPGVLTKLAKCCTPVPGD I
Sbjct  607  LVAQLGGVDSAEEELAERSTPSTMPIRQRRSDDVGVAVPGAPGVLTKLAKCCTPVPGDQI  666

Query  669  MGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRHRLLSD  728
            +GFVTRGGGVSVHRTDCTNA SLQQQ+ERIIEV WAPS SSVFLVAIQVEALDRHRLLSD
Sbjct  667  LGFVTRGGGVSVHRTDCTNAESLQQQSERIIEVHWAPSASSVFLVAIQVEALDRHRLLSD  726

Query  729  VTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDVYRVTS  788
            VTRALADE+VNILSASVTTS DRVAISRFTFEMGDPKHLGH+LN VRNVEGVYDVYRVTS
Sbjct  727  VTRALADERVNILSASVTTSNDRVAISRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRVTS  786

Query  789  AA  790
            AA
Sbjct  787  AA  788


>gi|333991010|ref|YP_004523624.1| GTP pyrophosphokinase RelA [Mycobacterium sp. JDM601]
 gi|333486978|gb|AEF36370.1| GTP pyrophosphokinase RelA [Mycobacterium sp. JDM601]
Length=793

 Score = 1389 bits (3595),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 680/768 (89%), Positives = 723/768 (95%), Gaps = 0/768 (0%)

Query  23   PALETPESPVETLKTSISASRRVRARLARRMTAQRSTTNPVLEPLVAVHREIYPKADLSI  82
            P  ++P    + LK   SASRRVRAR+ARR+TAQR   +PVLEPLVAVHR+ YPKA+L++
Sbjct  26   PDQDSPTERTDLLKVPTSASRRVRARIARRITAQRGALSPVLEPLVAVHRQFYPKANLAL  85

Query  83   LQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVAALLHDTVEDTGYTL  142
            LQRAYEVA+QRHA+QLR SGDPYITHPLAVA ILAELGMDTTTLVAALLHDTVEDTGYTL
Sbjct  86   LQRAYEVAEQRHATQLRHSGDPYITHPLAVATILAELGMDTTTLVAALLHDTVEDTGYTL  145

Query  143  EALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDPRVLVIKVADRLHNM  202
            EAL  EFG+EV HLVDGVTKLD+VVLG+AAE ETIRKM+ AMARDPRVLVIKVADRLHNM
Sbjct  146  EALAGEFGDEVAHLVDGVTKLDKVVLGTAAEAETIRKMVIAMARDPRVLVIKVADRLHNM  205

Query  203  RTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELEDLSFAILHPKKYEEIVRLVAG  262
            RT+RFLPPEKQARKARETLEVIAPLAHRLGMA+VKWELEDLSFAILHPKKYEEIVRLVA 
Sbjct  206  RTIRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELEDLSFAILHPKKYEEIVRLVAD  265

Query  263  RAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVR  322
            RAPSRDTYLAKVR EI+NTL  SKI A VEGRPKHYWSIYQKMIV+GRDFDDI+DLVG+R
Sbjct  266  RAPSRDTYLAKVRTEIINTLAKSKIAANVEGRPKHYWSIYQKMIVRGRDFDDIYDLVGLR  325

Query  323  ILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRT  382
            ILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTV+GPEGKPLE+QIRT
Sbjct  326  ILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVIGPEGKPLEIQIRT  385

Query  383  RDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQREAADPGEFLES  442
            R+MHRTAEYGIAAHWRYKEAKGRNGV HP+AAAEIDDMAWMRQLLDWQREAADPGEFLES
Sbjct  386  REMHRTAEYGIAAHWRYKEAKGRNGVPHPNAAAEIDDMAWMRQLLDWQREAADPGEFLES  445

Query  443  LRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKLE  502
            LRYDLAV+EIFVFTPKGDVITLP GSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKLE
Sbjct  446  LRYDLAVKEIFVFTPKGDVITLPNGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKLE  505

Query  503  NGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWFAKERREEALETGKDAMAREVRR  562
            NGEVVEVFTSKA NAGPSRDWQQFVVSPRAK KIRQWFAKERREEALE+GKDA+AREVRR
Sbjct  506  NGEVVEVFTSKAQNAGPSRDWQQFVVSPRAKAKIRQWFAKERREEALESGKDAIAREVRR  565

Query  563  GGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEE  622
             GLPLQRL++GESM AVARELHY+DVSALYTA+GE H+SA HVVQRL+A+LGG+DQAEE+
Sbjct  566  MGLPLQRLISGESMVAVARELHYSDVSALYTAVGENHISAHHVVQRLVAQLGGVDQAEED  625

Query  623  LAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHR  682
            LAERSTP T+PRR R TDDVGV+VPGA GVLTKLAKCCTPVPGD IMGFVTRGGGVSVHR
Sbjct  626  LAERSTPLTIPRRERHTDDVGVAVPGASGVLTKLAKCCTPVPGDEIMGFVTRGGGVSVHR  685

Query  683  TDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRHRLLSDVTRALADEKVNILS  742
            TDCTNA +L+QQAERIIEV WAPSPSSVFLVAIQVEALDRHRLLSDVT+ LADEKVNILS
Sbjct  686  TDCTNADALRQQAERIIEVKWAPSPSSVFLVAIQVEALDRHRLLSDVTKVLADEKVNILS  745

Query  743  ASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDVYRVTSAA  790
            ASVTTS DRVAISRFTFEMGDPKHLGHLLN VRNVEGVYDVYRVTSAA
Sbjct  746  ASVTTSRDRVAISRFTFEMGDPKHLGHLLNVVRNVEGVYDVYRVTSAA  793


>gi|289444121|ref|ZP_06433865.1| GTP pyrophosphokinase relA [Mycobacterium tuberculosis T46]
 gi|289417040|gb|EFD14280.1| GTP pyrophosphokinase relA [Mycobacterium tuberculosis T46]
Length=729

 Score = 1355 bits (3507),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 665/670 (99%), Positives = 666/670 (99%), Gaps = 0/670 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            +AEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT
Sbjct  1    MAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG
Sbjct  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS
Sbjct  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM
Sbjct  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE
Sbjct  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF
Sbjct  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV
Sbjct  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660
            SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC
Sbjct  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCC  660

Query  661  TPVPGDVIMG  670
            TPVPG    G
Sbjct  661  TPVPGRCDYG  670


>gi|111023852|ref|YP_706824.1| GTP diphosphokinase [Rhodococcus jostii RHA1]
 gi|110823382|gb|ABG98666.1| GTP diphosphokinase [Rhodococcus jostii RHA1]
Length=791

 Score = 1348 bits (3488),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 649/739 (88%), Positives = 691/739 (94%), Gaps = 5/739 (0%)

Query  53   MTAQRSTT-NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +T QR+TT  PVLEPLV++HRE+YPKADL++LQRAY+VA++RHASQ R+SGDPYITHPLA
Sbjct  57   ITGQRNTTIRPVLEPLVSLHRELYPKADLALLQRAYDVAEERHASQRRKSGDPYITHPLA  116

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            VA+ILAELGMDTTTLVAALLHDTVEDTGY+LE LT+EFGEEV HLVDGVTKLD+VVLG+A
Sbjct  117  VASILAELGMDTTTLVAALLHDTVEDTGYSLEQLTDEFGEEVAHLVDGVTKLDKVVLGNA  176

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AEGETIRKMI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL
Sbjct  177  AEGETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  236

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GMA+VKWELEDLSFAILHPKKY+EIVRLVA RAPSRDTYLAKVRAEI  TLTAS+I A V
Sbjct  237  GMATVKWELEDLSFAILHPKKYDEIVRLVADRAPSRDTYLAKVRAEINATLTASRINAVV  296

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDE+RDCYAAVGVVHSLWQPMAGRFKD
Sbjct  297  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEVRDCYAAVGVVHSLWQPMAGRFKD  356

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRT DMHRTAE+GIAAHWRYKE+KGR    H 
Sbjct  357  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTHDMHRTAEFGIAAHWRYKESKGR----HS  412

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
               AE+DDMAWMRQLLDWQREAADPGEFLESLRYDLAV+EIFVFTPKGDV+TLP GSTPV
Sbjct  413  GDVAEVDDMAWMRQLLDWQREAADPGEFLESLRYDLAVKEIFVFTPKGDVVTLPAGSTPV  472

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKA NAGPSRDWQ FVVSPR
Sbjct  473  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAVNAGPSRDWQTFVVSPR  532

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            AKTKIRQWFAKERREEALE GKDA+A+EVRR GLPLQRL+N ESMA++A ELHY DVS L
Sbjct  533  AKTKIRQWFAKERREEALEAGKDAIAKEVRRVGLPLQRLMNAESMASIAHELHYTDVSML  592

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            YTA+GE HVSA+HVVQRL+A LGG+   EEELAERSTP+TMP RPRST D GV VPGA G
Sbjct  593  YTAVGESHVSAQHVVQRLVAHLGGVGDVEEELAERSTPSTMPMRPRSTGDAGVLVPGAEG  652

Query  652  VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVF  711
             + KLAKCCTPVPGD IMGFVTRGG VSVHRTDCTNA SLQ+Q+ERII V WAPSPSSVF
Sbjct  653  TVAKLAKCCTPVPGDEIMGFVTRGGAVSVHRTDCTNAGSLQEQSERIIAVKWAPSPSSVF  712

Query  712  LVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL  771
            LVAIQ+EALDRHRLLSDVT+ALADEKVNILSASVTTSGDRVAIS+FTFEMGDPKHLGH+L
Sbjct  713  LVAIQIEALDRHRLLSDVTKALADEKVNILSASVTTSGDRVAISKFTFEMGDPKHLGHVL  772

Query  772  NAVRNVEGVYDVYRVTSAA  790
            N VRNVEGVYDVYRVTSAA
Sbjct  773  NVVRNVEGVYDVYRVTSAA  791


>gi|226366288|ref|YP_002784071.1| GTP pyrophosphokinase/guanosine-3',5'-bis (diphosphate) 3-pyrophosphohydrolase 
[Rhodococcus opacus B4]
 gi|226244778|dbj|BAH55126.1| GTP pyrophosphokinase/guanosine-3',5'-bis (diphosphate) 3-pyrophosphohydrolase 
[Rhodococcus opacus B4]
Length=791

 Score = 1347 bits (3487),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 649/739 (88%), Positives = 690/739 (94%), Gaps = 5/739 (0%)

Query  53   MTAQRSTT-NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +T QR+TT  PVLEPLV++HRE+YPKADL++LQRAY+VA++RHASQ R+SGDPYITHPLA
Sbjct  57   ITGQRNTTIRPVLEPLVSLHRELYPKADLALLQRAYDVAEERHASQRRKSGDPYITHPLA  116

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            VA+ILAELGMDTTTLVAALLHDTVEDTGY+LE LT+EFGEEV HLVDGVTKLD+VVLG+A
Sbjct  117  VASILAELGMDTTTLVAALLHDTVEDTGYSLEQLTDEFGEEVAHLVDGVTKLDKVVLGNA  176

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AEGETIRKMI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL
Sbjct  177  AEGETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  236

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GMA+VKWELEDLSFAILHPKKY+EIVRLVA RAPSRDTYLAKVRAEI  TLTAS+I A V
Sbjct  237  GMATVKWELEDLSFAILHPKKYDEIVRLVADRAPSRDTYLAKVRAEINATLTASRINAVV  296

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDE+RDCYAAVGVVHSLWQPMAGRFKD
Sbjct  297  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEVRDCYAAVGVVHSLWQPMAGRFKD  356

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRT DMHRTAE+GIAAHWRYKE KGR    H 
Sbjct  357  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTHDMHRTAEFGIAAHWRYKETKGR----HS  412

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
               AE+DDMAWMRQLLDWQREAADPGEFLESLRYDLAV+EIFVFTPKGDV+TLP GSTPV
Sbjct  413  GDVAEVDDMAWMRQLLDWQREAADPGEFLESLRYDLAVKEIFVFTPKGDVVTLPAGSTPV  472

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKA NAGPSRDWQ F VSPR
Sbjct  473  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAVNAGPSRDWQMFAVSPR  532

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            AKTKIRQWFAKERREEALE GKDA+A+EVRR GLPLQRL+N ESMA++A ELHY DVS L
Sbjct  533  AKTKIRQWFAKERREEALEAGKDAIAKEVRRVGLPLQRLMNAESMASIAHELHYTDVSML  592

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            YTA+GE HVSA+HVVQRL+A LGG+   EEELAERSTP+TMP RPRST D GV VPGA G
Sbjct  593  YTAVGESHVSAQHVVQRLVAHLGGVGDVEEELAERSTPSTMPMRPRSTGDAGVLVPGAEG  652

Query  652  VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVF  711
             + KLAKCCTPVPGD IMGFVTRGG VSVHRTDCTNA SLQ+Q+ERIIEV WAPSPSSVF
Sbjct  653  TVAKLAKCCTPVPGDEIMGFVTRGGAVSVHRTDCTNAGSLQEQSERIIEVKWAPSPSSVF  712

Query  712  LVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL  771
            LVAIQ+EALDRHRLLSDVT+ALADEKVNILSASVTTSGDRVAIS+FTFEMGDPKHLGH+L
Sbjct  713  LVAIQIEALDRHRLLSDVTKALADEKVNILSASVTTSGDRVAISKFTFEMGDPKHLGHVL  772

Query  772  NAVRNVEGVYDVYRVTSAA  790
            N VRNVEGVYDVYRVTSAA
Sbjct  773  NVVRNVEGVYDVYRVTSAA  791


>gi|312139501|ref|YP_004006837.1| gtp diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase 
[Rhodococcus equi 103S]
 gi|325672609|ref|ZP_08152305.1| GTP diphosphokinase [Rhodococcus equi ATCC 33707]
 gi|311888840|emb|CBH48152.1| GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase 
[Rhodococcus equi 103S]
 gi|325556486|gb|EGD26152.1| GTP diphosphokinase [Rhodococcus equi ATCC 33707]
Length=778

 Score = 1336 bits (3457),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 643/739 (88%), Positives = 688/739 (94%), Gaps = 5/739 (0%)

Query  53   MTAQRST-TNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +T QR+    PVLEPLVAVHRE+YPKAD S+LQRAY+VA+QRHA+Q R+SGDPYITHPLA
Sbjct  44   ITGQRNAPIRPVLEPLVAVHRELYPKADFSLLQRAYDVAEQRHATQFRKSGDPYITHPLA  103

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            VANILAELGMDTTTLVAALLHDTVEDTGY+LE LT EFG+EV HLVDGVTKLD+VVLGSA
Sbjct  104  VANILAELGMDTTTLVAALLHDTVEDTGYSLEELTAEFGDEVAHLVDGVTKLDKVVLGSA  163

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AEGETIRKMI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL
Sbjct  164  AEGETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  223

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GMA+VKWELEDLSFAILHPKKYEEIVRLVA RAPSRDTYLAKVRAEI  TL+AS+I A V
Sbjct  224  GMATVKWELEDLSFAILHPKKYEEIVRLVADRAPSRDTYLAKVRAEINATLSASRINAVV  283

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD
Sbjct  284  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  343

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPRYGVYQSLHTTV+GPEGKPLEVQIRTRDMHRTAE+GIAAHWRYKE KG+    H 
Sbjct  344  YIAQPRYGVYQSLHTTVIGPEGKPLEVQIRTRDMHRTAEFGIAAHWRYKETKGK----HS  399

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
            +  AE+DDMAWMRQLLDWQREAADPGEFLESLRYDLAV+EIFVFTPKGDV+TLP GSTPV
Sbjct  400  NDIAEVDDMAWMRQLLDWQREAADPGEFLESLRYDLAVKEIFVFTPKGDVVTLPAGSTPV  459

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            DFAYAVHTEVGHRCIGARVNGRLVALER LENGEVVEVFTSKAPNAGPSRDWQ FVVSPR
Sbjct  460  DFAYAVHTEVGHRCIGARVNGRLVALERTLENGEVVEVFTSKAPNAGPSRDWQTFVVSPR  519

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            AK KIRQWFAKERREEALE GKDA+AREVRRGGLPLQRL+N E+M A+A EL Y DVSAL
Sbjct  520  AKAKIRQWFAKERREEALEAGKDAIAREVRRGGLPLQRLLNAEAMTALAHELRYTDVSAL  579

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            YTA+GE +VSA+HVVQRL+A LGG    EEELAERSTP+T+P R R++ DVGV VPGAPG
Sbjct  580  YTAVGEHNVSAQHVVQRLVAHLGGETAVEEELAERSTPSTIPTRSRTSGDVGVLVPGAPG  639

Query  652  VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVF  711
             + KLAKCCTPVPGD IMGFVTRGG VSVHRTDCTNA SL++Q+ERII+V WAPSP+S+F
Sbjct  640  TVAKLAKCCTPVPGDEIMGFVTRGGAVSVHRTDCTNATSLREQSERIIDVEWAPSPTSLF  699

Query  712  LVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL  771
            LVAIQ+EALDRHRLLSDVT+ALADEKVNILSASVTTSGDRVA+S+FTFEMGDPKHLGH+L
Sbjct  700  LVAIQIEALDRHRLLSDVTKALADEKVNILSASVTTSGDRVAVSKFTFEMGDPKHLGHVL  759

Query  772  NAVRNVEGVYDVYRVTSAA  790
            N VRNVEGVYDVYRVTSAA
Sbjct  760  NVVRNVEGVYDVYRVTSAA  778


>gi|308374621|ref|ZP_07667828.1| GTP pyrophosphokinase relA [Mycobacterium tuberculosis SUMu006]
 gi|308341285|gb|EFP30136.1| GTP pyrophosphokinase relA [Mycobacterium tuberculosis SUMu006]
Length=765

 Score = 1322 bits (3421),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 651/651 (100%), Positives = 651/651 (100%), Gaps = 0/651 (0%)

Query  1    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  60
            VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT
Sbjct  4    VAEDQLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTT  63

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
            NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG
Sbjct  64   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  123

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM
Sbjct  124  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  183

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL
Sbjct  184  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  243

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS
Sbjct  244  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  303

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV
Sbjct  304  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  363

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM
Sbjct  364  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  423

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE
Sbjct  424  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  483

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF
Sbjct  484  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  543

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV
Sbjct  544  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  603

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG
Sbjct  604  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  654


>gi|229492002|ref|ZP_04385819.1| RelA/SpoT family protein [Rhodococcus erythropolis SK121]
 gi|229321134|gb|EEN86938.1| RelA/SpoT family protein [Rhodococcus erythropolis SK121]
Length=803

 Score = 1314 bits (3400),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 631/739 (86%), Positives = 682/739 (93%), Gaps = 5/739 (0%)

Query  53   MTAQRSTT-NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +T QR+ T  PVLEPLV++HRE+YPKADL++LQRAY+VA+ RH+SQ R+SGDPYITHPLA
Sbjct  69   ITGQRNATIRPVLEPLVSLHRELYPKADLALLQRAYDVAEDRHSSQRRKSGDPYITHPLA  128

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            VA+ILAELGMDTTTLVAALLHDTVEDTGY+LE LT++FG+EV HLVDGVTKLD+VVLG+A
Sbjct  129  VASILAELGMDTTTLVAALLHDTVEDTGYSLEELTKDFGDEVAHLVDGVTKLDKVVLGTA  188

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AEGETIRKMI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL
Sbjct  189  AEGETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  248

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GMA+VKWELEDLSFAILHPKKY+EIVRLVA RAPSRDTYLAKVRAEI +TL+AS+I A V
Sbjct  249  GMATVKWELEDLSFAILHPKKYDEIVRLVADRAPSRDTYLAKVRAEINSTLSASRINAIV  308

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILC+E+RDCYAAVGVVHSLWQPMAGRFKD
Sbjct  309  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCEEVRDCYAAVGVVHSLWQPMAGRFKD  368

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRT+DMHRTAE+GIAAHWRYKE KG+    H 
Sbjct  369  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTQDMHRTAEFGIAAHWRYKETKGK----HA  424

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
               AE+DDMAWMRQLLDWQREAADPGEFLESLRYDLAV+EIFVFTPKGDVITLP GSTPV
Sbjct  425  GDIAEVDDMAWMRQLLDWQREAADPGEFLESLRYDLAVKEIFVFTPKGDVITLPAGSTPV  484

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            DFAYAVHTEVGHRCIGARVNGRLVALER LENGEVVEVFTSKA  AGPSRDWQ FVVSPR
Sbjct  485  DFAYAVHTEVGHRCIGARVNGRLVALERTLENGEVVEVFTSKAATAGPSRDWQTFVVSPR  544

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            AK KIRQWFAKERREEALE+GKD +A+EVRR GLPLQRL+N ESM+ +A EL Y DVSAL
Sbjct  545  AKAKIRQWFAKERREEALESGKDQIAKEVRRVGLPLQRLMNAESMSTIAHELRYPDVSAL  604

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            YTA+GE  VSA HVVQRL+A LGG+   EEELAERSTP+TMP R RST D G+ VPGAPG
Sbjct  605  YTAVGESQVSAHHVVQRLVAHLGGVGAVEEELAERSTPSTMPVRTRSTGDSGILVPGAPG  664

Query  652  VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVF  711
             + KLAKCCTPVPGD I+GFVTRGG VSVHRTDCTNA SL  Q+ERII+V WAPS +SVF
Sbjct  665  TVAKLAKCCTPVPGDSILGFVTRGGAVSVHRTDCTNANSLHDQSERIIDVEWAPSATSVF  724

Query  712  LVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL  771
            LVAIQ+EALDRHRLLSDVT+ALADEKVNILSASVTTSGDRVAIS+FTFEMGDPKHLGH+L
Sbjct  725  LVAIQIEALDRHRLLSDVTKALADEKVNILSASVTTSGDRVAISKFTFEMGDPKHLGHVL  784

Query  772  NAVRNVEGVYDVYRVTSAA  790
            N VRNVEGVYDVYRVTSA+
Sbjct  785  NVVRNVEGVYDVYRVTSAS  803


>gi|226306418|ref|YP_002766378.1| GTP pyrophosphokinase/guanosine-3',5'-bis (diphosphate) 3-pyrophosphohydrolase 
[Rhodococcus erythropolis PR4]
 gi|226185535|dbj|BAH33639.1| GTP pyrophosphokinase/guanosine-3',5'-bis (diphosphate) 3-pyrophosphohydrolase 
[Rhodococcus erythropolis PR4]
Length=809

 Score = 1312 bits (3395),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 631/739 (86%), Positives = 682/739 (93%), Gaps = 5/739 (0%)

Query  53   MTAQRSTT-NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +T QR+ T  PVLEPLV++HRE+YPKADL++LQRAY+VA+ RH+SQ R+SGDPYITHPLA
Sbjct  75   ITGQRNATIRPVLEPLVSLHRELYPKADLALLQRAYDVAEDRHSSQRRKSGDPYITHPLA  134

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            VA+ILAELGMDTTTLVAALLHDTVEDTGY+LE LT++FG+EV HLVDGVTKLD+VVLG+A
Sbjct  135  VASILAELGMDTTTLVAALLHDTVEDTGYSLEELTKDFGDEVAHLVDGVTKLDKVVLGTA  194

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AEGETIRKMI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL
Sbjct  195  AEGETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  254

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GMA+VKWELEDLSFAILHPKKY+EIVRLVA RAPSRDTYLAKVRAEI +TL+AS+I A V
Sbjct  255  GMATVKWELEDLSFAILHPKKYDEIVRLVADRAPSRDTYLAKVRAEINSTLSASRINAIV  314

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILC+E+RDCYAAVGVVHSLWQPMAGRFKD
Sbjct  315  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCEEVRDCYAAVGVVHSLWQPMAGRFKD  374

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRT+DMHRTAE+GIAAHWRYKE KG+    H 
Sbjct  375  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTQDMHRTAEFGIAAHWRYKETKGK----HA  430

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
               AE+DDMAWMRQLLDWQREAADPGEFLESLRYDLAV+EIFVFTPKGDVITLP GSTPV
Sbjct  431  GDIAEVDDMAWMRQLLDWQREAADPGEFLESLRYDLAVKEIFVFTPKGDVITLPAGSTPV  490

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            DFAYAVHTEVGHRCIGARVNGRLVALER LENGEVVEVFTSKA  AGPSRDWQ FVVSPR
Sbjct  491  DFAYAVHTEVGHRCIGARVNGRLVALERTLENGEVVEVFTSKAATAGPSRDWQTFVVSPR  550

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            AK KIRQWFAKERREEALE+GKD +A+EVRR GLPLQRL+N ESM+ +A EL Y DVSAL
Sbjct  551  AKAKIRQWFAKERREEALESGKDQIAKEVRRVGLPLQRLMNAESMSTIAHELRYPDVSAL  610

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            YTA+GE  VSA HVVQRL+A LGG+   EEELAERSTP+TMP R RST D G+ VPGAPG
Sbjct  611  YTAVGESQVSAHHVVQRLVAHLGGVGAVEEELAERSTPSTMPVRTRSTGDSGILVPGAPG  670

Query  652  VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVF  711
             + KLAKCCTPVPGD I+GFVTRGG VSVHRTDCTNA SL  Q+ERII+V WAPS +SVF
Sbjct  671  TVAKLAKCCTPVPGDSILGFVTRGGAVSVHRTDCTNANSLHDQSERIIDVEWAPSATSVF  730

Query  712  LVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL  771
            LVAIQ+EALDRHRLLSDVT+ALADEKVNILSASVTTSGDRVAIS+FTFEMGDPKHLGH+L
Sbjct  731  LVAIQIEALDRHRLLSDVTKALADEKVNILSASVTTSGDRVAISKFTFEMGDPKHLGHVL  790

Query  772  NAVRNVEGVYDVYRVTSAA  790
            N VRNVEGVYDVYRVTSA+
Sbjct  791  NVVRNVEGVYDVYRVTSAS  809


>gi|54025654|ref|YP_119896.1| putative ppGpp synthetase [Nocardia farcinica IFM 10152]
 gi|54017162|dbj|BAD58532.1| putative ppGpp synthetase [Nocardia farcinica IFM 10152]
Length=798

 Score = 1286 bits (3328),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 617/740 (84%), Positives = 669/740 (91%), Gaps = 6/740 (0%)

Query  53   MTAQR--STTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPL  110
            MT QR  +   PVLEPL  VHRE+YPKA+L+ LQ+A++VAD+RHA Q R+SGDPYITHPL
Sbjct  63   MTGQRGIAAVKPVLEPLATVHRELYPKANLAQLQKAFDVADERHAHQFRKSGDPYITHPL  122

Query  111  AVANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGS  170
            AVANILAELGMDTTTLVAALLHDTVEDTGYTL+ L  EFG+EV HLVDGVTKLD+V LG+
Sbjct  123  AVANILAELGMDTTTLVAALLHDTVEDTGYTLDQLRAEFGDEVAHLVDGVTKLDKVNLGA  182

Query  171  AAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHR  230
            AAE ETIRKMI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQA+KA+ETLEVIAPLAHR
Sbjct  183  AAEAETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQAKKAKETLEVIAPLAHR  242

Query  231  LGMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKAT  290
            LGMA+VKWELEDL+FAILHPKKY+EIVRLVA RAPSRDTYLAKVRAEIVNTL AS+I A 
Sbjct  243  LGMATVKWELEDLAFAILHPKKYDEIVRLVADRAPSRDTYLAKVRAEIVNTLAASRINAV  302

Query  291  VEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFK  350
            VEGRPKHYWSIYQKMIVKG+DFDDIHDLVG+RILCDE+RDCYAAVGVVHSLWQPMAGRFK
Sbjct  303  VEGRPKHYWSIYQKMIVKGKDFDDIHDLVGIRILCDEVRDCYAAVGVVHSLWQPMAGRFK  362

Query  351  DYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLH  410
            DYIAQPRYGVYQSLHTTVVGP+GKPLEVQIRT DMHRTAE+GIAAHWRYKE KG+    H
Sbjct  363  DYIAQPRYGVYQSLHTTVVGPDGKPLEVQIRTHDMHRTAEFGIAAHWRYKETKGK----H  418

Query  411  PHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTP  470
                AE+DDMAWMRQLLDWQREAADP EFLESLR+DL   EIFVFTPKGDVITLP  STP
Sbjct  419  SGDLAEVDDMAWMRQLLDWQREAADPAEFLESLRFDLKSPEIFVFTPKGDVITLPQKSTP  478

Query  471  VDFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSP  530
            VDFAYAVHTEVGHRCIGARVNGRLVALER+LENGEVVEVFTSKA NAGPSRDWQ FVVSP
Sbjct  479  VDFAYAVHTEVGHRCIGARVNGRLVALERQLENGEVVEVFTSKAQNAGPSRDWQNFVVSP  538

Query  531  RAKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSA  590
            RAK KIRQWFAKERREEALE+GK+ +++EVRR GLPLQRL++ ++M AVA ELHY D+S+
Sbjct  539  RAKAKIRQWFAKERREEALESGKEQISKEVRRVGLPLQRLMSVDAMTAVAHELHYTDISS  598

Query  591  LYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAP  650
            LYTA+GE  VSA HVVQRL+A+LGGI   E ELAERSTP+T P R R T D GV +PGAP
Sbjct  599  LYTAVGEHQVSAHHVVQRLMAQLGGIGDVENELAERSTPSTTPSRQRVTGDAGVLIPGAP  658

Query  651  GVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSV  710
            G + KLAKCCTPVPGD IMGFVTRGG VSVHRTDCTNAASL++Q+ERII+V WAPSPSSV
Sbjct  659  GTVAKLAKCCTPVPGDEIMGFVTRGGAVSVHRTDCTNAASLREQSERIIDVEWAPSPSSV  718

Query  711  FLVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHL  770
            FLVAIQ+EALDR RLLSDVT+ LADEKVNILSASV T GDRVAIS+FTFEMGDPKHLGHL
Sbjct  719  FLVAIQIEALDRTRLLSDVTKVLADEKVNILSASVATHGDRVAISKFTFEMGDPKHLGHL  778

Query  771  LNAVRNVEGVYDVYRVTSAA  790
            LN VRNVEGVYDVYRVTSAA
Sbjct  779  LNVVRNVEGVYDVYRVTSAA  798


>gi|296139654|ref|YP_003646897.1| (p)ppGpp synthetase I SpoT/RelA [Tsukamurella paurometabola DSM 
20162]
 gi|296027788|gb|ADG78558.1| (p)ppGpp synthetase I, SpoT/RelA [Tsukamurella paurometabola 
DSM 20162]
Length=779

 Score = 1284 bits (3323),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 638/777 (83%), Positives = 692/777 (90%), Gaps = 2/777 (0%)

Query  13   PPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQRSTTNPVLEPLVAVHR  72
            P   + AA  P  E    P   L+ + S +RRVRARLARRMT  R+   PVLEPLVA+HR
Sbjct  4    PSQGSDAARTPTAEAAPQP-PNLEQTGSTTRRVRARLARRMTGTRNHVRPVLEPLVALHR  62

Query  73   EIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVAALLH  132
            E+YPKAD+++++RAY+VA+QRHA+Q+R+SGDPYITHPLAVA ILAELGMDTTTLVAALLH
Sbjct  63   EVYPKADVALIERAYDVAEQRHATQMRKSGDPYITHPLAVATILAELGMDTTTLVAALLH  122

Query  133  DTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDPRVLV  192
            DTVEDTGY+L+ LT EFG EV HLVDGVTKLD+V LGSAAE ETIRKMI AMARDPRVLV
Sbjct  123  DTVEDTGYSLDQLTAEFGSEVAHLVDGVTKLDKVALGSAAEAETIRKMIIAMARDPRVLV  182

Query  193  IKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELEDLSFAILHPKK  252
            IKVADRLHNMRTMRFLPPEKQARKA+ETLEVIAPLAHRLGMA+VKWELEDLSFAILHPKK
Sbjct  183  IKVADRLHNMRTMRFLPPEKQARKAKETLEVIAPLAHRLGMATVKWELEDLSFAILHPKK  242

Query  253  YEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWSIYQKMIVKGRDF  312
            Y+EIVRLVA RAPSRDTYLA VRAEI   LTAS+I A V+GRPKHYWSIYQKMIVKGRDF
Sbjct  243  YDEIVRLVADRAPSRDTYLASVRAEINGALTASRIVADVQGRPKHYWSIYQKMIVKGRDF  302

Query  313  DDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPE  372
            DDIHDLVGVRILCDE+RDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTV+GPE
Sbjct  303  DDIHDLVGVRILCDEVRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVIGPE  362

Query  373  GKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLDWQRE  432
            GKPLEVQIRTRDMHRTAE+GIAAHWRYKE KG+ G       +E+DDMAWMRQLLDWQRE
Sbjct  363  GKPLEVQIRTRDMHRTAEFGIAAHWRYKETKGKGGKGGSD-LSEVDDMAWMRQLLDWQRE  421

Query  433  AADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCIGARVNG  492
            AADPGEFLESLRYDLAV+EIFVFTPKGDVI LP GSTPVDFAYAVHTEVGHRCIGARVNG
Sbjct  422  AADPGEFLESLRYDLAVKEIFVFTPKGDVINLPAGSTPVDFAYAVHTEVGHRCIGARVNG  481

Query  493  RLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWFAKERREEALETG  552
            RLVALERKLENGEVVEVFTSKA NAGPSRDWQ FVVSPRAK KIRQWFAKERREEALE G
Sbjct  482  RLVALERKLENGEVVEVFTSKAENAGPSRDWQSFVVSPRAKAKIRQWFAKERREEALENG  541

Query  553  KDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHVSAKHVVQRLLAE  612
            +DA+A+EVRR GLPLQRL N ESMA +A+EL YADVSALYTA+GE  VSA  VVQR+L +
Sbjct  542  RDAIAKEVRRSGLPLQRLTNAESMAGIAKELRYADVSALYTAVGEHQVSAHTVVQRMLEQ  601

Query  613  LGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFV  672
            LGG ++A EELAERSTP+T+      + DVGV V G PGVL KLAKCCTPVPGD I+GFV
Sbjct  602  LGGFEEATEELAERSTPSTLSGPSTPSTDVGVLVTGQPGVLAKLAKCCTPVPGDEIVGFV  661

Query  673  TRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRHRLLSDVTRA  732
            TRGGGVSVHRTDCTN A L+++ ER ++V WAPSPSSVFLVAIQVEALDRHRLLSDVT+ 
Sbjct  662  TRGGGVSVHRTDCTNVAELRKEPERFLDVKWAPSPSSVFLVAIQVEALDRHRLLSDVTKV  721

Query  733  LADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDVYRVTSA  789
            LADEKVNILSASVTTS DRVA+SRFTFEMGDPKHLGH+LN VRNVEGVYDVYRVTSA
Sbjct  722  LADEKVNILSASVTTSRDRVAVSRFTFEMGDPKHLGHVLNVVRNVEGVYDVYRVTSA  778


>gi|343924320|ref|ZP_08763871.1| GTP pyrophosphokinase/guanosine-3',5'-bis (diphosphate) 3-pyrophosphohydrolase 
[Gordonia alkanivorans NBRC 16433]
 gi|343765754|dbj|GAA10797.1| GTP pyrophosphokinase/guanosine-3',5'-bis (diphosphate) 3-pyrophosphohydrolase 
[Gordonia alkanivorans NBRC 16433]
Length=787

 Score = 1283 bits (3321),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 621/738 (85%), Positives = 676/738 (92%), Gaps = 1/738 (0%)

Query  53   MTAQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAV  112
            MTA RS   PVLEPLV +HREIYPKAD+++LQRAY+VA++RH+ Q R+SGDPYITHPLAV
Sbjct  51   MTATRSQVRPVLEPLVTLHREIYPKADVALLQRAYDVAEERHSGQKRKSGDPYITHPLAV  110

Query  113  ANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAA  172
            A ILA+LGMDTTTL+AALLHDTVEDTGY+L+AL  +FG+EV HLVDGVTKLD+V LGSAA
Sbjct  111  ATILADLGMDTTTLIAALLHDTVEDTGYSLQALERDFGQEVAHLVDGVTKLDKVALGSAA  170

Query  173  EGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG  232
            E ETIRKMI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG
Sbjct  171  EAETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG  230

Query  233  MASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVE  292
            MA+VKWELEDLSFAILHPK+YEEIVRLVA RAPSRDTYLA+VRA+I N L+A++I+ATVE
Sbjct  231  MATVKWELEDLSFAILHPKRYEEIVRLVADRAPSRDTYLARVRADINNALSAARIQATVE  290

Query  293  GRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDY  352
            GRPKHYWSIYQKMIVKGRDFDDIHDLVG+RILC+E RDCYAAVGVVHSLWQPMAGRFKDY
Sbjct  291  GRPKHYWSIYQKMIVKGRDFDDIHDLVGMRILCEEDRDCYAAVGVVHSLWQPMAGRFKDY  350

Query  353  IAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPH  412
            IAQPR+GVYQSLHTTV+GPEGKPLEVQIRT +MHRTAE+GIAAHWRYKE+  R       
Sbjct  351  IAQPRFGVYQSLHTTVIGPEGKPLEVQIRTHEMHRTAEFGIAAHWRYKESGYRKSG-KKS  409

Query  413  AAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVD  472
              AEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAV+EIFVFTPKGDV+TLP GSTPVD
Sbjct  410  DTAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVREIFVFTPKGDVVTLPAGSTPVD  469

Query  473  FAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRA  532
            FAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAP AGPS+DWQ FVVSPRA
Sbjct  470  FAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPTAGPSKDWQTFVVSPRA  529

Query  533  KTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALY  592
            K KIRQWFAKERREEALETGKDA+A+EVRRGGLPLQRL++ ESMAA+A+EL Y DV+ALY
Sbjct  530  KAKIRQWFAKERREEALETGKDAIAKEVRRGGLPLQRLLSAESMAAIAKELRYNDVTALY  589

Query  593  TAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGV  652
             A+GE HVSA+HVV RL+A LGGI+ AEE LAERSTP+TMP R R   D GV V G   V
Sbjct  590  AAVGENHVSARHVVNRLVASLGGIEDAEEALAERSTPSTMPTRSRQGGDAGVVVDGVDNV  649

Query  653  LTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFL  712
            + KLAKCCTPVPGD IMGFVTRGGG+SVHRTDCTNA SLQQQ+ERI++V WAPSP SVFL
Sbjct  650  VIKLAKCCTPVPGDDIMGFVTRGGGISVHRTDCTNATSLQQQSERILDVSWAPSPESVFL  709

Query  713  VAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN  772
            VAIQVEALDRHRLLSDVT+ LADE+VNILSASVTTS DRVAIS+FTFEMGDPKHLGH+LN
Sbjct  710  VAIQVEALDRHRLLSDVTKVLADERVNILSASVTTSRDRVAISKFTFEMGDPKHLGHVLN  769

Query  773  AVRNVEGVYDVYRVTSAA  790
             VRNVEGVYDVYRVTSAA
Sbjct  770  VVRNVEGVYDVYRVTSAA  787


>gi|333919490|ref|YP_004493071.1| GTP diphosphokinase [Amycolicicoccus subflavus DQS3-9A1]
 gi|333481711|gb|AEF40271.1| GTP diphosphokinase [Amycolicicoccus subflavus DQS3-9A1]
Length=730

 Score = 1278 bits (3307),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 609/730 (84%), Positives = 671/730 (92%), Gaps = 5/730 (0%)

Query  61   NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELG  120
             PVLEPLVA+HRE YPKA L+ LQRAY+VA+ +H+ Q+R+SGDPYITHPLAVA+ILAELG
Sbjct  4    KPVLEPLVAIHREFYPKAPLATLQRAYDVAESKHSEQVRKSGDPYITHPLAVASILAELG  63

Query  121  MDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKM  180
            MDTTTL+AALLHDTVEDTGY+LE L E+FGEEV HLVDGVTKLD+VVLGSAAE ETIRKM
Sbjct  64   MDTTTLIAALLHDTVEDTGYSLEQLREDFGEEVAHLVDGVTKLDKVVLGSAAEAETIRKM  123

Query  181  ITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWEL  240
            I AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMA+VKWEL
Sbjct  124  IIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWEL  183

Query  241  EDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWS  300
            EDL+FAILHPK+YEEIVRLVA RAPSRD YL KVR +I + L+A+K+ A VEGRPKHYWS
Sbjct  184  EDLAFAILHPKRYEEIVRLVADRAPSRDIYLEKVRKQIDDALSAAKLNAVVEGRPKHYWS  243

Query  301  IYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGV  360
            IYQKMIVKG+DFD+IHDLVG+R+LCDE+R CYAAVGVVHSLWQPMA RFKDYIAQPRYGV
Sbjct  244  IYQKMIVKGKDFDEIHDLVGIRVLCDEVRGCYAAVGVVHSLWQPMAQRFKDYIAQPRYGV  303

Query  361  YQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDM  420
            YQSLHTTVVGPEGKPLEVQIRT +MHRTAEYGIAAHWRYKE KG+    H + A E+DD+
Sbjct  304  YQSLHTTVVGPEGKPLEVQIRTHEMHRTAEYGIAAHWRYKETKGK----HSNDATEVDDI  359

Query  421  AWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTE  480
            AWMRQLLDWQREAADPGEFLESLRYDLA++EIFVFTPKGDV+TLP GSTPVDFAYAVHTE
Sbjct  360  AWMRQLLDWQREAADPGEFLESLRYDLALKEIFVFTPKGDVVTLPVGSTPVDFAYAVHTE  419

Query  481  VGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWF  540
            VGHRCIGARVNGRLV LER L+NGEVVE+FTSKA NAGPSRDWQ FVVSPRAKTKIRQWF
Sbjct  420  VGHRCIGARVNGRLVPLERNLDNGEVVEIFTSKAENAGPSRDWQTFVVSPRAKTKIRQWF  479

Query  541  AKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHV  600
            AKERREEALE GKDA+A+EVRR GLPLQR+++G+ MAA AREL Y DV ALY A+GE HV
Sbjct  480  AKERREEALEAGKDAIAKEVRRSGLPLQRILSGDLMAATARELRYQDVDALYAAVGEHHV  539

Query  601  SAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRST-DDVGVSVPGAPGVLTKLAKC  659
            SA+HVVQRL+A+ GG+D AEEELAER+TP++ P+R R T  DVGV VPGA G+L KLAKC
Sbjct  540  SAQHVVQRLVAQFGGVDDAEEELAERATPSSTPKRHRRTAGDVGVQVPGATGILVKLAKC  599

Query  660  CTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEA  719
            CTPVPGD IMGFVTRGGGVSVHRTDCTNA+SL+ ++ER+I+V WAPSP S+FLVAIQ+EA
Sbjct  600  CTPVPGDDIMGFVTRGGGVSVHRTDCTNASSLRTESERLIDVRWAPSPHSMFLVAIQIEA  659

Query  720  LDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEG  779
            LDRHRLLSDVT+ALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGH+LN VRNVEG
Sbjct  660  LDRHRLLSDVTKALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHVLNVVRNVEG  719

Query  780  VYDVYRVTSA  789
            VYDVYRVTSA
Sbjct  720  VYDVYRVTSA  729


>gi|262202238|ref|YP_003273446.1| RelA/SpoT family protein [Gordonia bronchialis DSM 43247]
 gi|262085585|gb|ACY21553.1| RelA/SpoT family protein [Gordonia bronchialis DSM 43247]
Length=790

 Score = 1272 bits (3292),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 615/738 (84%), Positives = 670/738 (91%), Gaps = 0/738 (0%)

Query  53   MTAQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAV  112
            MTA RS   PVLEPLV +HREIYPKAD+++LQ AY+VA++RH  Q R+SGDPYITHPLAV
Sbjct  53   MTATRSQVRPVLEPLVTLHREIYPKADVALLQHAYDVAEERHRGQNRKSGDPYITHPLAV  112

Query  113  ANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAA  172
            A ILA+LGMDTTTLVAALLHDTVEDTGYTL+ L ++FG EV HLVDGVTKLD+V LGSAA
Sbjct  113  ATILADLGMDTTTLVAALLHDTVEDTGYTLDQLEKDFGAEVAHLVDGVTKLDKVALGSAA  172

Query  173  EGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG  232
            E ETIRKMI AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG
Sbjct  173  EAETIRKMIIAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLG  232

Query  233  MASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVE  292
            MA+VKWELEDLSFAILHPK+YEEIVRLVA RAPSRDTYLA+VRA+I N L+A++I ATVE
Sbjct  233  MATVKWELEDLSFAILHPKRYEEIVRLVADRAPSRDTYLARVRADINNALSAARISATVE  292

Query  293  GRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDY  352
            GRPKHYWSIYQKMIVKGRDFDDIHDLVG+RILCDE+RDCYAAVGVVHSLWQPMAGRFKDY
Sbjct  293  GRPKHYWSIYQKMIVKGRDFDDIHDLVGMRILCDEVRDCYAAVGVVHSLWQPMAGRFKDY  352

Query  353  IAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPH  412
            IAQPR+GVYQSLHTTV+GPEGKPLEVQIRT +MHRTAE+GIAAHWRYKE+  ++      
Sbjct  353  IAQPRFGVYQSLHTTVIGPEGKPLEVQIRTHEMHRTAEFGIAAHWRYKESGYKDRKGRRT  412

Query  413  AAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVD  472
             + EID+MAWMRQLLDWQREAADPGEFLESLRYDLAV+EIFVFTPKGDVITLP GSTPVD
Sbjct  413  DSTEIDEMAWMRQLLDWQREAADPGEFLESLRYDLAVREIFVFTPKGDVITLPAGSTPVD  472

Query  473  FAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRA  532
            FAYAVHTEVGHRCIGARVNGRLVALER+LENGE VEVFTSKAPNAGPSRDWQ FVVSPRA
Sbjct  473  FAYAVHTEVGHRCIGARVNGRLVALERQLENGERVEVFTSKAPNAGPSRDWQGFVVSPRA  532

Query  533  KTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALY  592
            K KIRQWFAKERREEALE GKDA+ +EVRRGGLPLQRL++ ESMAA+A+EL Y DV+ALY
Sbjct  533  KAKIRQWFAKERREEALEAGKDAIVKEVRRGGLPLQRLMSAESMAAIAKELRYTDVTALY  592

Query  593  TAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGV  652
            TA+GE HVSA+HVV RL+A LGGID A EE+AERSTP+TMP R R   D GV V G   V
Sbjct  593  TAVGENHVSARHVVNRLVAALGGIDDAAEEIAERSTPSTMPTRARQGGDAGVVVEGVDNV  652

Query  653  LTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFL  712
            + KLAKCCTPVPGD I+GFVTRGGG+SVHRTDCTNA SL+ Q+ERII+V W PS  SVFL
Sbjct  653  VIKLAKCCTPVPGDEILGFVTRGGGISVHRTDCTNAESLRAQSERIIDVTWVPSAESVFL  712

Query  713  VAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLN  772
            VAIQVEALDRHRLLSDVT+ LADE+VNILSASVTTS DRVAIS+FTFEMGDPKHLGH+LN
Sbjct  713  VAIQVEALDRHRLLSDVTKVLADERVNILSASVTTSRDRVAISKFTFEMGDPKHLGHVLN  772

Query  773  AVRNVEGVYDVYRVTSAA  790
             VRNVEGVYDVYRVTSAA
Sbjct  773  VVRNVEGVYDVYRVTSAA  790


>gi|326382134|ref|ZP_08203826.1| RelA/SpoT family protein [Gordonia neofelifaecis NRRL B-59395]
 gi|326198864|gb|EGD56046.1| RelA/SpoT family protein [Gordonia neofelifaecis NRRL B-59395]
Length=729

 Score = 1233 bits (3190),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 592/732 (81%), Positives = 655/732 (90%), Gaps = 8/732 (1%)

Query  62   PVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELGM  121
            PVLEPLV +HRE+YPKAD+++LQ+AY VA++ H+ Q R+SGDPYITHPLAVA ILA+LGM
Sbjct  3    PVLEPLVTLHREVYPKADVAVLQQAYSVAEEHHSGQFRKSGDPYITHPLAVATILADLGM  62

Query  122  DTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMI  181
            DTTTLVAALLHDTVEDTGY+L+ L  +FG EV HLVDGVTKLD+V LGSAAE ETIRKMI
Sbjct  63   DTTTLVAALLHDTVEDTGYSLDQLEADFGTEVAHLVDGVTKLDKVALGSAAEAETIRKMI  122

Query  182  TAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELE  241
             AMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMA+VKWELE
Sbjct  123  IAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMATVKWELE  182

Query  242  DLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWSI  301
            DL+FAILHPKKYEEIVRLVA RAPSRDTYLA+VR+++   L AS+I ATVEGRPKHYWSI
Sbjct  183  DLAFAILHPKKYEEIVRLVADRAPSRDTYLARVRSDLNTALGASRITATVEGRPKHYWSI  242

Query  302  YQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVY  361
            YQKMIVKG+DFDDIHDLVG+RILCDE+RDCYAA+GVVHSLWQPMAGRFKDYIAQP +GVY
Sbjct  243  YQKMIVKGKDFDDIHDLVGMRILCDEVRDCYAAIGVVHSLWQPMAGRFKDYIAQPSFGVY  302

Query  362  QSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKE---AKGRNGVLHPHAAAEID  418
            QSLHTTV+GPEGKPLEVQIRT +MHRTAE+GIAAHWRYKE    KGR         AE+D
Sbjct  303  QSLHTTVIGPEGKPLEVQIRTFEMHRTAEFGIAAHWRYKEGRKGKGRKAT----DVAEVD  358

Query  419  DMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVH  478
            DMAWMRQLLDWQREAADPGEFLESLRYDLAV+EIFVFTPKGDVITLP GSTP+DFAYAVH
Sbjct  359  DMAWMRQLLDWQREAADPGEFLESLRYDLAVKEIFVFTPKGDVITLPAGSTPIDFAYAVH  418

Query  479  TEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQ  538
            TEVGHRCIGARVNGRLVALER LENGEVVEVFTSKA NAGPS+DWQ FVVSPRAK KIRQ
Sbjct  419  TEVGHRCIGARVNGRLVALERALENGEVVEVFTSKAENAGPSKDWQNFVVSPRAKAKIRQ  478

Query  539  WFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEG  598
            WFAKERREEALE GK+A+ +EVRRGGLP+ RL++GES+ A+A+E  +ADV ALYTA+GE 
Sbjct  479  WFAKERREEALEAGKEAIIKEVRRGGLPVHRLLSGESVNALAKEFGFADVDALYTAVGEN  538

Query  599  HVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPGVLTKLAK  658
            HV A  VV RL+A LGG+D AEEE+A R+TP++  RR R + D GV V G   VL KLAK
Sbjct  539  HVPAGRVVHRLVAMLGGVDAAEEEIANRATPSSTTRR-RQSGDSGVVVEGIDNVLVKLAK  597

Query  659  CCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVE  718
            CCTPVPGD I+GFVTRGGGVSVHR DCTNA  L+ Q ER+I+V WAP+PSSVFLVAIQVE
Sbjct  598  CCTPVPGDEILGFVTRGGGVSVHRADCTNADDLRGQPERLIQVSWAPNPSSVFLVAIQVE  657

Query  719  ALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVE  778
            ALDRHRLLSDVTR LADE+VNILSAS+TT+ DRVA+S+FTFEMGDPKHLGH+LN VRNVE
Sbjct  658  ALDRHRLLSDVTRVLADERVNILSASLTTNRDRVAVSKFTFEMGDPKHLGHVLNVVRNVE  717

Query  779  GVYDVYRVTSAA  790
            GVYDVYRVTSAA
Sbjct  718  GVYDVYRVTSAA  729


>gi|134098602|ref|YP_001104263.1| GTP pyrophosphokinase [Saccharopolyspora erythraea NRRL 2338]
 gi|291008201|ref|ZP_06566174.1| GTP pyrophosphokinase [Saccharopolyspora erythraea NRRL 2338]
 gi|133911225|emb|CAM01338.1| GTP pyrophosphokinase [Saccharopolyspora erythraea NRRL 2338]
Length=771

 Score = 1211 bits (3133),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 583/739 (79%), Positives = 658/739 (90%), Gaps = 3/739 (0%)

Query  53   MTAQRST-TNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +TAQR+T    VLEPL AVHRE++P+ADL++LQRAY+VA+ +H  Q R+SGDPYITHPLA
Sbjct  35   ITAQRATQVKQVLEPLAAVHRELHPQADLALLQRAYDVAEDKHRDQRRKSGDPYITHPLA  94

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            V+ ILAELGMDTTTLVAALLHDTVEDT Y+LE L+ +FGEEV HLVDGVTKLD+V LG+A
Sbjct  95   VSTILAELGMDTTTLVAALLHDTVEDTDYSLERLSGDFGEEVSHLVDGVTKLDKVKLGAA  154

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AE ETIRKMI AMARDPRVLVIK+ADRLHNMRTMRFLPPEKQARKARETLEV+APLAHRL
Sbjct  155  AEAETIRKMIIAMARDPRVLVIKLADRLHNMRTMRFLPPEKQARKARETLEVLAPLAHRL  214

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GMA+VKWELEDL+FAIL PKKY+EIVRLVA RAPSRDTYL  V  E+   L  +++ A V
Sbjct  215  GMATVKWELEDLAFAILQPKKYDEIVRLVANRAPSRDTYLRTVIDELSGQLDTARLAARV  274

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHY+SI+QKMIV+GRDFDDIHDLVGVRIL DE+RDCYAA+GVVH+LWQPM GRFKD
Sbjct  275  EGRPKHYYSIHQKMIVRGRDFDDIHDLVGVRILVDEVRDCYAAMGVVHALWQPMPGRFKD  334

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPR+GVYQSLHTTV+GPEGKPLEVQIRT +MHRTAEYGIAAHWRYKE KGRNG    
Sbjct  335  YIAQPRFGVYQSLHTTVIGPEGKPLEVQIRTHEMHRTAEYGIAAHWRYKETKGRNGG-SG  393

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
            H A E+D+MAWMRQLLDWQREAADPGEFLESLRYDLA +EIFVFTPKGDVITLP+GSTPV
Sbjct  394  HTAVEVDEMAWMRQLLDWQREAADPGEFLESLRYDLATREIFVFTPKGDVITLPSGSTPV  453

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            DFAY VHTEVGHRCIGARVNGRLVALERKLENGEVVE+FTSKA  AGPSRDW  FV SPR
Sbjct  454  DFAYTVHTEVGHRCIGARVNGRLVALERKLENGEVVEIFTSKAEGAGPSRDWLSFVASPR  513

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            AK KI+QWFAKERREEA+E+GK+A+A+E+RR GLP+QRLV+ ES+ AVARELHY DV+AL
Sbjct  514  AKAKIKQWFAKERREEAIESGKEAIAKELRRLGLPIQRLVSAESIGAVARELHYVDVTAL  573

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            Y A+GE  +SA H+V RL+A +GG+DQA +E+AERSTP+T+  R R+T D GV V  A  
Sbjct  574  YAAVGEKQISAGHLVSRLVASVGGVDQAADEIAERSTPSTIQGR-RTTGDSGVVVKDAGD  632

Query  652  VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVF  711
            V  KLA+CCTPVPGD I+GFVTRGGGVSVHRTDCTNA  L++  ER++EV WAPS SSVF
Sbjct  633  VWAKLARCCTPVPGDDILGFVTRGGGVSVHRTDCTNADELRKSPERLVEVYWAPSASSVF  692

Query  712  LVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL  771
            LVAIQVEALDRHRLLSDVT+ LADE+VNILSASVTTS DRVA+SRF+FEMGDPKHLGH+L
Sbjct  693  LVAIQVEALDRHRLLSDVTKVLADERVNILSASVTTSKDRVAVSRFSFEMGDPKHLGHVL  752

Query  772  NAVRNVEGVYDVYRVTSAA  790
             AVRN+EGVYDVYRVTSA+
Sbjct  753  KAVRNIEGVYDVYRVTSAS  771


>gi|296393867|ref|YP_003658751.1| (p)ppGpp synthetase I [Segniliparus rotundus DSM 44985]
 gi|296181014|gb|ADG97920.1| (p)ppGpp synthetase I, SpoT/RelA [Segniliparus rotundus DSM 44985]
Length=797

 Score = 1202 bits (3111),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 577/748 (78%), Positives = 658/748 (88%), Gaps = 6/748 (0%)

Query  45   VRARLARRMTAQR-STTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGD  103
            +R+R+AR + A R S   P LEPL A+HRE+YPKA L++L +AY++A  RH  Q R+SGD
Sbjct  54   LRSRIARSLGAGRGSGVQPELEPLAALHRELYPKASLALLAKAYDIAQARHEGQFRRSGD  113

Query  104  PYITHPLAVANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKL  163
            PYITHPLAVA+ILAELGMDT +LVAALLHDTVEDTGY+LE L  +FG +V H+VDGVTKL
Sbjct  114  PYITHPLAVAHILAELGMDTLSLVAALLHDTVEDTGYSLEELERDFGSDVAHIVDGVTKL  173

Query  164  DRVVLGSAAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEV  223
            D+V  G+ AE ETIRKM+ AMARDPRVLVIKVADRLHNMRTMRF+PPEKQ RKA+ETLEV
Sbjct  174  DKVTWGAGAEAETIRKMVIAMARDPRVLVIKVADRLHNMRTMRFMPPEKQVRKAQETLEV  233

Query  224  IAPLAHRLGMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLT  283
            IAPLAHRLGMASVKWELEDL+FA+LHPKKY EIVRLVA RAPSRDTYLA+V++E+ + L+
Sbjct  234  IAPLAHRLGMASVKWELEDLAFAVLHPKKYAEIVRLVADRAPSRDTYLARVKSELQSALS  293

Query  284  ASKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQ  343
            + ++ A V GRPKHYWSIYQKMIVKGRDFDDIHDLVG+RI+C E+RDCYAAVGVVHSLWQ
Sbjct  294  SFRVDAEVAGRPKHYWSIYQKMIVKGRDFDDIHDLVGLRIVCGEVRDCYAAVGVVHSLWQ  353

Query  344  PMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAK  403
            P+ GRFKDYIAQPRYGVYQSLHTTV+GPEGKPLEVQ+RT++MHR AE+GIAAHWRYKE K
Sbjct  354  PLPGRFKDYIAQPRYGVYQSLHTTVIGPEGKPLEVQLRTQEMHRVAEFGIAAHWRYKENK  413

Query  404  GRNGVLHPHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVIT  463
            G+ G      AAE+D MAWMRQLLDWQREA+DPG+FLE LRYDLAV+EIFVFTPKGDVIT
Sbjct  414  GKVG----SDAAEVDRMAWMRQLLDWQREASDPGDFLEDLRYDLAVREIFVFTPKGDVIT  469

Query  464  LPTGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDW  523
            LP GSTPVDFAYAVHTEVGHRCIGARV+GRLVALER LENGEVVEVFTSKA NAGP+RDW
Sbjct  470  LPAGSTPVDFAYAVHTEVGHRCIGARVDGRLVALERPLENGEVVEVFTSKAANAGPTRDW  529

Query  524  QQFVVSPRAKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVAREL  583
            Q FVVSPRA+TKIRQWFAKERREEALE GK ++A+EVRR GLPLQR++  ++M+AVA EL
Sbjct  530  QSFVVSPRARTKIRQWFAKERREEALEAGKASIAKEVRRSGLPLQRILGADTMSAVAGEL  589

Query  584  HYADVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMP-RRPRSTDDV  642
            HY DVSALYTA+GE HVSA+ VVQ L+   GG ++A E   ERS+  TMP R  R ++D 
Sbjct  590  HYPDVSALYTAVGENHVSAQKVVQCLVTHFGGEEEAAEAAQERSSTTTMPARTSRRSEDC  649

Query  643  GVSVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVL  702
            GV V G+    TKLAKCCTPVPGD I+GFVTRGG VSVHR DCTN+ASL  Q ER+I+V+
Sbjct  650  GVQVVGSADTPTKLAKCCTPVPGDKILGFVTRGGFVSVHRVDCTNSASLHTQQERLIDVV  709

Query  703  WAPSPSSVFLVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMG  762
            WAPSPSSVFLVAIQVEALDRHRLLSD+T+ALADE+VNILSASVTTSGDRVA+S+FTFE+G
Sbjct  710  WAPSPSSVFLVAIQVEALDRHRLLSDITKALADERVNILSASVTTSGDRVALSKFTFEIG  769

Query  763  DPKHLGHLLNAVRNVEGVYDVYRVTSAA  790
            DPKHLGHLL+AVRNVEGVYDVYR+TSAA
Sbjct  770  DPKHLGHLLSAVRNVEGVYDVYRLTSAA  797


>gi|317508687|ref|ZP_07966342.1| RelA/SpoT family protein [Segniliparus rugosus ATCC BAA-974]
 gi|316253008|gb|EFV12423.1| RelA/SpoT family protein [Segniliparus rugosus ATCC BAA-974]
Length=797

 Score = 1194 bits (3089),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 592/788 (76%), Positives = 674/788 (86%), Gaps = 11/788 (1%)

Query  5    QLTAQAVAPPTEASAALEPALETPESPVETLKTSISASRRVRARLARRMTAQR-STTNPV  63
            Q+    VA P E   A +PA   P         S  +  R+R+R+AR + A R S   P 
Sbjct  19   QIPGTGVAVPEEP--AQQPA---PPGTNAVPGPSPKSGGRLRSRIARSLGAGRGSGLQPE  73

Query  64   LEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELGMDT  123
            LEPL A+HRE+YPKA L +L +AYE+A+ RH  Q R+SGDPYITHPLAVA+ILAELGMDT
Sbjct  74   LEPLAALHRELYPKASLGLLAKAYEIAEVRHKGQFRRSGDPYITHPLAVAHILAELGMDT  133

Query  124  TTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITA  183
             +LVAALLHDTVEDTGY+LE L  +FG +V H+VDGVTKLD+V  G+ AE ETIRKM+ A
Sbjct  134  LSLVAALLHDTVEDTGYSLEELERDFGSDVAHIVDGVTKLDKVTWGAGAEAETIRKMVIA  193

Query  184  MARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELEDL  243
            MARDPRVLVIKVADRLHNMRTMRF+PPEKQ RKA+ETLEVIAPLAHRLGMASVKWELEDL
Sbjct  194  MARDPRVLVIKVADRLHNMRTMRFMPPEKQVRKAQETLEVIAPLAHRLGMASVKWELEDL  253

Query  244  SFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWSIYQ  303
            +FA+LHPKKY EIVRLVA RAPSRDTYLA+V+ E+ + L++ ++ A V GRPKHYWSIYQ
Sbjct  254  AFAVLHPKKYAEIVRLVADRAPSRDTYLARVKGELQSALSSFRVDAKVAGRPKHYWSIYQ  313

Query  304  KMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQS  363
            KMIVKGRDFDDIHDLVG+R++C E+RDCYAAVGVVHSLWQP+ GRFKDYIAQPRYGVYQS
Sbjct  314  KMIVKGRDFDDIHDLVGLRVVCGEVRDCYAAVGVVHSLWQPLPGRFKDYIAQPRYGVYQS  373

Query  364  LHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWM  423
            LHTTV+GPEGKPLEVQ+RT++MHR AE+GIAAHWRYKE KG+ G      +AE+D MAWM
Sbjct  374  LHTTVIGPEGKPLEVQLRTKEMHRVAEFGIAAHWRYKENKGKVG----SDSAEVDRMAWM  429

Query  424  RQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGH  483
            RQLLDWQREA+DPG+FLE LRYDLAV+EIFVFTPKGDVITLP+GSTPVDFAYAVHTEVGH
Sbjct  430  RQLLDWQREASDPGDFLEDLRYDLAVKEIFVFTPKGDVITLPSGSTPVDFAYAVHTEVGH  489

Query  484  RCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWFAKE  543
            RCIGARV+GRLVALER LENGEV+EVFTSKA +AGPSRDWQ FVVS RA+TKIRQWFAKE
Sbjct  490  RCIGARVDGRLVALERPLENGEVIEVFTSKAASAGPSRDWQGFVVSARARTKIRQWFAKE  549

Query  544  RREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHVSAK  603
            RREEALE GK A+A+EVRR GLPLQR++NGE+MA+VA ELHY DVSALYTA+GE HVSA+
Sbjct  550  RREEALEAGKAAIAKEVRRSGLPLQRILNGETMASVAGELHYPDVSALYTAVGESHVSAQ  609

Query  604  HVVQRLLAELGGIDQAEEELAERSTPATMP-RRPRSTDDVGVSVPGAPGVLTKLAKCCTP  662
             VVQ L+A  GG ++A E   ER+  AT+P R  R ++D GV V G+    TKLAKCCTP
Sbjct  610  KVVQCLVAHFGGEEEAAEAAVERAGAATLPVRTRRRSEDCGVQVVGSSDTPTKLAKCCTP  669

Query  663  VPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDR  722
            VPGD I+GFVTRGG VSVHR DCTN+ASLQ Q ER+IEV WAPSPSSVFLVAIQVEALDR
Sbjct  670  VPGDKILGFVTRGGFVSVHRVDCTNSASLQAQQERLIEVAWAPSPSSVFLVAIQVEALDR  729

Query  723  HRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYD  782
            HRLLSD+T+ALADE+VNILSASVTTSGDRVA+S+FTFE+GDPKHLGHLL+AVRNVEGVYD
Sbjct  730  HRLLSDITKALADERVNILSASVTTSGDRVALSKFTFEIGDPKHLGHLLSAVRNVEGVYD  789

Query  783  VYRVTSAA  790
            VYRVTSAA
Sbjct  790  VYRVTSAA  797


>gi|331697364|ref|YP_004333603.1| (p)ppGpp synthetase I, SpoT/RelA [Pseudonocardia dioxanivorans 
CB1190]
 gi|326952053|gb|AEA25750.1| (p)ppGpp synthetase I, SpoT/RelA [Pseudonocardia dioxanivorans 
CB1190]
Length=821

 Score = 1193 bits (3087),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 590/787 (75%), Positives = 677/787 (87%), Gaps = 11/787 (1%)

Query  12   APPTEASAALEPALETPESPVET--LKTSISASRRVRARLARRMTAQR-STTNPVLEPLV  68
            AP +   ++  P+   P +P  T    T  SA+RRVRAR+ARRMT QR +   PVLEPL 
Sbjct  38   APSSTGRSSPAPSNPAPSNPAPTGTAVTKPSATRRVRARIARRMTPQRVAIVKPVLEPLA  97

Query  69   AVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILAELGMDTTTLVA  128
             VHR ++P ADL +LQRAY+VA+ +HA Q R+SGDPYITHPLAVA ILAELGMDTTTLVA
Sbjct  98   TVHRTLHPNADLGLLQRAYDVAEAKHAHQKRKSGDPYITHPLAVATILAELGMDTTTLVA  157

Query  129  ALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDP  188
            ALLHDTVEDT Y+LE L  +FG+EV HLVDGVTKLD+V  G+AAE ETIRKM+ AMARDP
Sbjct  158  ALLHDTVEDTDYSLERLRTDFGDEVAHLVDGVTKLDKVEFGTAAEAETIRKMVVAMARDP  217

Query  189  RVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELEDLSFAIL  248
            RVLVIK++DRLHNMRTMRFLPPEKQA+KARETLEV+APLAHRLGMA+VKWELEDLSFAIL
Sbjct  218  RVLVIKLSDRLHNMRTMRFLPPEKQAKKARETLEVMAPLAHRLGMATVKWELEDLSFAIL  277

Query  249  HPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKHYWSIYQKMIVK  308
            HPKKYEEIVRLVA RAPSRDTYL +V  E++  L  ++I ATVEGRPKHY+SIY+KMIVK
Sbjct  278  HPKKYEEIVRLVATRAPSRDTYLKQVIDEVMQQLEGARITATVEGRPKHYYSIYRKMIVK  337

Query  309  GRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTV  368
            GRDFDDIHDLVGVR+L DE+RDCYAA+G+VH+LWQPM GRFKDYIAQPR+GVYQSLHTTV
Sbjct  338  GRDFDDIHDLVGVRVLVDEVRDCYAAMGMVHALWQPMPGRFKDYIAQPRFGVYQSLHTTV  397

Query  369  VGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEIDDMAWMRQLLD  428
            +GP+GKPLEVQIRTR+MHRTAE+GIAAHWRYKE++G +         EID+M+WMRQLLD
Sbjct  398  IGPDGKPLEVQIRTREMHRTAEFGIAAHWRYKESRGSHAAT--AGTVEIDEMSWMRQLLD  455

Query  429  WQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAVHTEVGHRCIGA  488
            WQREAADPG+FLESLR+DLA QEIFVFTPKGDV+TLPTGSTPVD AYAVHTEVG+RCIG+
Sbjct  456  WQREAADPGDFLESLRFDLASQEIFVFTPKGDVVTLPTGSTPVDLAYAVHTEVGNRCIGS  515

Query  489  RVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIRQWFAKERREEA  548
            RVNGRLVALER LE+G+VVE+FTSKA  AGPSRDW QFV SPRAKTKI+ WFAKERREEA
Sbjct  516  RVNGRLVALERTLESGDVVEIFTSKAEGAGPSRDWLQFVASPRAKTKIKHWFAKERREEA  575

Query  549  LETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGEGHVSAKHVVQR  608
            +E GKDA+ RE RR G+PLQRL + +SMAA+ARELHY D+S LY A+GEGH SA+HVVQR
Sbjct  576  IEAGKDAITREARRTGMPLQRLASPDSMAALARELHYPDLSGLYAAVGEGHASARHVVQR  635

Query  609  LLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG-----VLTKLAKCCTPV  663
            L+A LGG++ AEEELAER+TP+T+ R+ R T D GV+V    G     + TKLA+CCTPV
Sbjct  636  LVALLGGMEDAEEELAERATPSTV-RQRRPTGDAGVTVVNPDGTSAGDMYTKLARCCTPV  694

Query  664  PGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQVEALDRH  723
            PGD I+GFVTRGGG+SVHRTDCTNA  LQ + ER+++V W+ SP SVFLVAIQVEALDRH
Sbjct  695  PGDDILGFVTRGGGISVHRTDCTNAHDLQSRQERLVDVAWSVSPGSVFLVAIQVEALDRH  754

Query  724  RLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNAVRNVEGVYDV  783
            RLLSDVT+ LADE+VNILSASVTTS DRVA+SRF+FEMGDPKHLGHLL  VRNVEGVYDV
Sbjct  755  RLLSDVTKVLADERVNILSASVTTSRDRVAVSRFSFEMGDPKHLGHLLRTVRNVEGVYDV  814

Query  784  YRVTSAA  790
            YRVTSA 
Sbjct  815  YRVTSAG  821


>gi|256375833|ref|YP_003099493.1| (p)ppGpp synthetase I SpoT/RelA [Actinosynnema mirum DSM 43827]
 gi|255920136|gb|ACU35647.1| (p)ppGpp synthetase I, SpoT/RelA [Actinosynnema mirum DSM 43827]
Length=766

 Score = 1192 bits (3084),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 576/739 (78%), Positives = 651/739 (89%), Gaps = 6/739 (0%)

Query  53   MTAQRST-TNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +TAQR+     VLEPL AVHR+++P ADL +LQRAY+VA+++H  Q R+SGDPYITHPLA
Sbjct  33   ITAQRAAPVKQVLEPLAAVHRDLHPNADLGLLQRAYDVAEEKHRPQRRKSGDPYITHPLA  92

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            VA ILAELGMDTTTLVAALLHDTVEDT Y+L+ L ++FG  V  LVDGVTKLD+V LG+A
Sbjct  93   VATILAELGMDTTTLVAALLHDTVEDTDYSLDQLRDDFGTVVALLVDGVTKLDKVKLGAA  152

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AE ETIRKM+ AMA+DPRVLVIK+ADRLHNMRTMRFLPPEKQARKARETLEV+APLAHRL
Sbjct  153  AEAETIRKMVIAMAKDPRVLVIKLADRLHNMRTMRFLPPEKQARKARETLEVLAPLAHRL  212

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GMA+VKWELEDL+FAIL PKKY+EIVRLVA RAPSRDTYL+ V  E+   L  +++ A V
Sbjct  213  GMATVKWELEDLAFAILQPKKYDEIVRLVANRAPSRDTYLSGVINELSGHLEGARLTAKV  272

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHY+SI QKMIV+GRDFDDIHDLVGVRI  DE+RDCYAA+GVVH+LWQPM GRFKD
Sbjct  273  EGRPKHYYSINQKMIVRGRDFDDIHDLVGVRIQVDEVRDCYAAMGVVHALWQPMPGRFKD  332

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPR+GVYQSLHTTV+GP+GKPLEVQIRT DMHRTAEYGIAAHWRYKE KG     H 
Sbjct  333  YIAQPRFGVYQSLHTTVIGPDGKPLEVQIRTYDMHRTAEYGIAAHWRYKETKGS----HR  388

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
              + E+D+MAWMRQLLDWQREAADPGEFLESLR+DLA +EIFVFTPKGDV+TLPTGSTPV
Sbjct  389  GKSVEVDEMAWMRQLLDWQREAADPGEFLESLRFDLAAREIFVFTPKGDVVTLPTGSTPV  448

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVE+FTSKA  AGPSRDW  F  SPR
Sbjct  449  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEIFTSKAEGAGPSRDWLSFAQSPR  508

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            AK KI+QWFAKER+EEA+E GKDA+A+EVRR GLPLQRLV+ ++M A+A+ELHY DVSAL
Sbjct  509  AKAKIKQWFAKERKEEAIEVGKDAIAKEVRRVGLPLQRLVSADAMGALAKELHYPDVSAL  568

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            Y A+GEGH SA+HVVQRL+A+LGG+D AE+ELAERSTP+T+ RR R T D GV V  +  
Sbjct  569  YAAVGEGHTSARHVVQRLVAQLGGVDHAEDELAERSTPSTVARR-RVTGDAGVIVKDSSD  627

Query  652  VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVF  711
            V  KLA+CCTPVPGD I+GFVTRGGGVSVHRTDCTNA  L +  ER+++V WAPS SSVF
Sbjct  628  VWVKLARCCTPVPGDDILGFVTRGGGVSVHRTDCTNADELLKTPERLLDVEWAPSSSSVF  687

Query  712  LVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL  771
            LVAIQVEALDRHRLLSDVT+ LADEKVNILSASVTTS DRVA+SRF+FEMGDPKHLGH+L
Sbjct  688  LVAIQVEALDRHRLLSDVTKVLADEKVNILSASVTTSRDRVAVSRFSFEMGDPKHLGHVL  747

Query  772  NAVRNVEGVYDVYRVTSAA  790
             AVR+VEGVYDVYRVTSA+
Sbjct  748  KAVRSVEGVYDVYRVTSAS  766


>gi|257055543|ref|YP_003133375.1| (p)ppGpp synthetase, RelA/SpoT family [Saccharomonospora viridis 
DSM 43017]
 gi|256585415|gb|ACU96548.1| (p)ppGpp synthetase, RelA/SpoT family [Saccharomonospora viridis 
DSM 43017]
Length=812

 Score = 1177 bits (3045),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 575/739 (78%), Positives = 655/739 (89%), Gaps = 6/739 (0%)

Query  53   MTAQR-STTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +TAQR ++   VLEPL A+HRE++P ADL++LQRAY+ A++ H  Q R+SGDPYITHPLA
Sbjct  79   ITAQRPASVKQVLEPLAAIHRELHPNADLALLQRAYDTAEELHRGQHRKSGDPYITHPLA  138

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            VA ILAELGMDTTTLVAALLHDTVEDTGY++E LTE+FGE+V  LVDGVTKLD+V LG+A
Sbjct  139  VATILAELGMDTTTLVAALLHDTVEDTGYSVEQLTEDFGEKVAQLVDGVTKLDKVKLGTA  198

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AE ETIRKM+ AMARDPRVLVIK+ADRLHNMRTMRFLPPEKQARKA+ETLEV+APLAHRL
Sbjct  199  AEAETIRKMVIAMARDPRVLVIKLADRLHNMRTMRFLPPEKQARKAKETLEVLAPLAHRL  258

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GM++VKWELEDL+FAIL PKKY+EIVRLVA RAPSRDTYL  V  E+   L  S+I A V
Sbjct  259  GMSTVKWELEDLAFAILQPKKYDEIVRLVADRAPSRDTYLRWVIGELTRQLEESRINAKV  318

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHY+SI+QKMIV+GRD DDIHDLVGVRIL +++RDCYAA+GVVH+LWQPM GRFKD
Sbjct  319  EGRPKHYYSIHQKMIVRGRDLDDIHDLVGVRILVEDVRDCYAAMGVVHALWQPMPGRFKD  378

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPRYGVYQSLHTTV+GP+GKPLEVQIRT +MHRTAEYGIAAHWRYKE KG     H 
Sbjct  379  YIAQPRYGVYQSLHTTVIGPDGKPLEVQIRTHEMHRTAEYGIAAHWRYKETKG----THK  434

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
              A EID+MAWMRQLLDWQREAADPGEFLESLRYDLA +EIFVFTPKGDVITLP GSTPV
Sbjct  435  GNAVEIDEMAWMRQLLDWQREAADPGEFLESLRYDLATREIFVFTPKGDVITLPVGSTPV  494

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            DFAYAVHTEVGHRCIGARVNGRLVALERKL+NGEVVE+FTSKA  AGPSRDW  FV SP+
Sbjct  495  DFAYAVHTEVGHRCIGARVNGRLVALERKLDNGEVVEIFTSKAEGAGPSRDWMSFVCSPK  554

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            AK KIRQWFAKERR+EA+E GK+A+A+EVR+ GLPLQRLV+ ++M+AVA+EL + D+S+L
Sbjct  555  AKAKIRQWFAKERRDEAIEAGKEAIAKEVRKVGLPLQRLVSADTMSAVAKELRHPDISSL  614

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            Y A+GE  V A+HVVQRL+A LGG+D+AEEELAER+TP+T+ RR R   DVGV V G   
Sbjct  615  YAAVGEHQVGAQHVVQRLVALLGGVDEAEEELAERATPSTVARR-RGAGDVGVVVKGQTD  673

Query  652  VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVF  711
            + TKLA+CCTPVPGD I+GFVTRGGGVSVHRTDCTNA  L++Q ER++EV WAP+ SSVF
Sbjct  674  IWTKLARCCTPVPGDEILGFVTRGGGVSVHRTDCTNANELRKQPERLLEVEWAPTESSVF  733

Query  712  LVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL  771
            LVAIQVEALDRHRLLSD+T+ LADE+VNILSASVTTS DRVA+SRFTFEMGDPKHLGH+L
Sbjct  734  LVAIQVEALDRHRLLSDITKVLADERVNILSASVTTSRDRVAVSRFTFEMGDPKHLGHVL  793

Query  772  NAVRNVEGVYDVYRVTSAA  790
              VRNVEGVYDVYRVTSA+
Sbjct  794  KIVRNVEGVYDVYRVTSAS  812


>gi|300787167|ref|YP_003767458.1| GTP pyrophosphokinase [Amycolatopsis mediterranei U32]
 gi|299796681|gb|ADJ47056.1| GTP pyrophosphokinase [Amycolatopsis mediterranei U32]
 gi|340528666|gb|AEK43871.1| GTP pyrophosphokinase [Amycolatopsis mediterranei S699]
Length=784

 Score = 1170 bits (3026),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 569/739 (77%), Positives = 651/739 (89%), Gaps = 6/739 (0%)

Query  53   MTAQRST-TNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +TAQR+     VLEPL  +HRE++P  DL +LQRAY+VA++ H +Q R+SGDPYITHPLA
Sbjct  51   ITAQRAAPVKQVLEPLAVIHRELHPNGDLGLLQRAYDVAEELHRNQRRKSGDPYITHPLA  110

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            VA ILAELGMDTTTLVAALLHDTVEDTGY +E+L  +FG++V  LVDGVTKLD+V LGS+
Sbjct  111  VATILAELGMDTTTLVAALLHDTVEDTGYAVESLKADFGDKVAELVDGVTKLDKVQLGSS  170

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AE ETIRKM+ AMA+DPRVLVIK+ADRLHNMRTMRFLPPEKQARKARETLEV+APLAHRL
Sbjct  171  AEAETIRKMVIAMAKDPRVLVIKLADRLHNMRTMRFLPPEKQARKARETLEVLAPLAHRL  230

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GMA+VKWELEDL+FAIL PKKY+EIVRLVA RAPSRD YL  V  ++ + L +S+I A V
Sbjct  231  GMATVKWELEDLAFAILQPKKYDEIVRLVADRAPSRDIYLRSVITDLTSNLVSSRITAKV  290

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHY+SI+QKMIV+GRD DDIHDLVGVRIL +++RDCYAA+GVVH+LWQP+ GRFKD
Sbjct  291  EGRPKHYYSIHQKMIVRGRDLDDIHDLVGVRILVEDVRDCYAAMGVVHALWQPVPGRFKD  350

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPR+GVYQSLHTTV+GP+GKPLEVQIRT +MHRTAEYGIAAHWRYKE KG     H 
Sbjct  351  YIAQPRFGVYQSLHTTVIGPDGKPLEVQIRTYEMHRTAEYGIAAHWRYKETKG----THT  406

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
              A ++D+MAWMRQLLDWQREAADPG+FLESLRY+LA +EIFVFTPKGDVITLP  STPV
Sbjct  407  GNAVDVDEMAWMRQLLDWQREAADPGDFLESLRYELASREIFVFTPKGDVITLPVESTPV  466

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVE+FTSKA NAGPSRDW QF  SP+
Sbjct  467  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEIFTSKAENAGPSRDWLQFAGSPK  526

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            A+ KIRQWFAKERR+EA+E GK+A+ +E+R+ GLP+QRLV+ ESM AVA EL +AD+S+L
Sbjct  527  ARAKIRQWFAKERRDEAIEGGKEAITKEIRKVGLPIQRLVSAESMGAVATELRHADISSL  586

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            Y A+GEGH SAKHVVQRL+A +GG+D AEEELAER+TP+T+ RR R ++DVGV V GA  
Sbjct  587  YAAVGEGHTSAKHVVQRLVALIGGVDAAEEELAERATPSTVTRR-RGSNDVGVVVKGASD  645

Query  652  VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVF  711
            V  KLA+CCTPVPGD I+GFVTRGGGVSVHRTDCTNA  LQ Q ER++EV WAPS SSVF
Sbjct  646  VWAKLARCCTPVPGDEILGFVTRGGGVSVHRTDCTNAGDLQSQPERLVEVEWAPSASSVF  705

Query  712  LVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL  771
            LVAIQVEALDRHRLLSDVT+ LADEKVNILSASVTTS DRVA+SRF+FEMGDPKHLGH+L
Sbjct  706  LVAIQVEALDRHRLLSDVTKVLADEKVNILSASVTTSRDRVAVSRFSFEMGDPKHLGHVL  765

Query  772  NAVRNVEGVYDVYRVTSAA  790
              VR VEGVYDVYRVTSA+
Sbjct  766  KVVRGVEGVYDVYRVTSAS  784


>gi|302527845|ref|ZP_07280187.1| GTP pyrophosphokinase [Streptomyces sp. AA4]
 gi|302436740|gb|EFL08556.1| GTP pyrophosphokinase [Streptomyces sp. AA4]
Length=777

 Score = 1167 bits (3019),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 568/739 (77%), Positives = 655/739 (89%), Gaps = 5/739 (0%)

Query  53   MTAQRST-TNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +TAQR+     VLEPL  +HRE++P +DL  LQRAY+VA++ H  Q R+SGDPYITHPLA
Sbjct  43   ITAQRAAPVKQVLEPLAVIHRELHPNSDLGQLQRAYDVAEELHREQRRKSGDPYITHPLA  102

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            VA ILAELGMDTTTLVAALLHDTVEDTGY+LE L  +FG++VG LVDGVTKLD+V LG++
Sbjct  103  VATILAELGMDTTTLVAALLHDTVEDTGYSLEQLKADFGDKVGELVDGVTKLDKVKLGTS  162

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AE ETIRKM+ AMA+DPRVLVIK+ADRLHNMRTMRFLPPEKQARKARETLEV+APLAHRL
Sbjct  163  AEAETIRKMVIAMAKDPRVLVIKLADRLHNMRTMRFLPPEKQARKARETLEVLAPLAHRL  222

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GMA+VKWELEDL+FAIL PKKY+EIVRLVA RAPSRDTYL KV A++ N L +S+I A V
Sbjct  223  GMATVKWELEDLAFAILQPKKYDEIVRLVADRAPSRDTYLRKVIADLTNNLVSSRITAKV  282

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHY+SI+QKMIV+GRD DDIHDLVGVRIL +++RDCYAA+GVVH+LWQP+ GRFKD
Sbjct  283  EGRPKHYYSIHQKMIVRGRDLDDIHDLVGVRILVEDVRDCYAAMGVVHALWQPVPGRFKD  342

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPR+GVYQSLHTTV+GP+GKPLEVQIRT DMHRTAEYGIAAHWRYKE KG +     
Sbjct  343  YIAQPRFGVYQSLHTTVIGPDGKPLEVQIRTYDMHRTAEYGIAAHWRYKETKGTHA---S  399

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
            + A E+D++AWMRQLLDWQREAADPG+FLESLRY+LA +EIFVFTPKGDVITLP  STPV
Sbjct  400  NNAMELDEIAWMRQLLDWQREAADPGDFLESLRYELAAREIFVFTPKGDVITLPADSTPV  459

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVE+FTSKA +AGPSRDW QF  SP+
Sbjct  460  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEIFTSKAESAGPSRDWLQFAGSPK  519

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            A+ KIRQWFAKERR+EA++ GK+A+ +E+R+ GLP+QRLV+ ESM +VA EL + D+S+L
Sbjct  520  ARAKIRQWFAKERRDEAIDAGKEAITKEIRKVGLPIQRLVSAESMGSVATELRHGDISSL  579

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            Y A+GEGH SAKHVVQRL+A +GG+++AEEELAER+TP+T+ RR R ++DVGV V GA  
Sbjct  580  YAAVGEGHTSAKHVVQRLVALIGGVEEAEEELAERATPSTVTRR-RGSNDVGVIVKGASD  638

Query  652  VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVF  711
            V  KLA+CCTPVPGD I+GFVTRGGGVSVHRTDCTNA  L+ Q ER++EV WAPS SSVF
Sbjct  639  VWAKLARCCTPVPGDEILGFVTRGGGVSVHRTDCTNADDLRTQPERLVEVEWAPSSSSVF  698

Query  712  LVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLL  771
            LVAIQVEALDRHRLLSDVT+ LADEKVNILSASVTTS DRVA+SRF+FEMGDPKHLGH+L
Sbjct  699  LVAIQVEALDRHRLLSDVTKVLADEKVNILSASVTTSRDRVAVSRFSFEMGDPKHLGHVL  758

Query  772  NAVRNVEGVYDVYRVTSAA  790
              VR VEGVYDVYRVTSA+
Sbjct  759  KVVRGVEGVYDVYRVTSAS  777


>gi|324999169|ref|ZP_08120281.1| (p)ppGpp synthetase I, SpoT/RelA [Pseudonocardia sp. P1]
Length=777

 Score = 1128 bits (2918),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 551/744 (75%), Positives = 639/744 (86%), Gaps = 12/744 (1%)

Query  53   MTAQR-STTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            MT QR +   PVLEPL AVHR ++PKADL +LQRAY+VA+ +H  Q R+SGDPYITHPLA
Sbjct  40   MTPQRVAIVKPVLEPLAAVHRSLHPKADLMLLQRAYDVAESKHEGQTRKSGDPYITHPLA  99

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            V+ ILAELGMDTTTLVAALLHDTVEDT Y+LE L  +FG+EV HLVDGVTKLD+V  G+A
Sbjct  100  VSTILAELGMDTTTLVAALLHDTVEDTDYSLERLRTDFGDEVAHLVDGVTKLDKVEFGTA  159

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            AE ETIRKM+ AMARDPRVLVIK++DRLHNMRTMRFL PEKQ +KA ETLEV APLAHRL
Sbjct  160  AEAETIRKMVVAMARDPRVLVIKLSDRLHNMRTMRFLRPEKQVKKANETLEVFAPLAHRL  219

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GMA+VK ELEDLSFAIL PKKY+EIVRLVA RAPSRDTYL +V  E+ + L +++I A V
Sbjct  220  GMATVKLELEDLSFAILQPKKYQEIVRLVADRAPSRDTYLRQVIDEVTSQLDSARIPAKV  279

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
            EGRPKHY+SIY+KMIVKGRDFDDIHDLVGVR+L +E+RDCYAA+G+VH+LWQPM GRFKD
Sbjct  280  EGRPKHYYSIYRKMIVKGRDFDDIHDLVGVRVLVEEVRDCYAAIGMVHALWQPMPGRFKD  339

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHP  411
            YIAQPR+GVYQSLHTTV+GP+GKPLEVQIRT  MHRTAEYGIAAHWRYKE KG       
Sbjct  340  YIAQPRFGVYQSLHTTVIGPDGKPLEVQIRTHAMHRTAEYGIAAHWRYKEIKGGQS----  395

Query  412  HAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPV  471
                E+++MAWMRQLLDWQREAADPGEFL+SLR+DLA +EIFVFTPKGDV+TLPTGSTP+
Sbjct  396  -KEVEVEEMAWMRQLLDWQREAADPGEFLDSLRFDLAAREIFVFTPKGDVVTLPTGSTPI  454

Query  472  DFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPR  531
            D AYAVHTEVGHRCIG+RVNG+LVALER+L +G+VVE+FTSKA +AGPSRDW     SPR
Sbjct  455  DLAYAVHTEVGHRCIGSRVNGKLVALERQLSSGDVVEIFTSKAEDAGPSRDWLAIAKSPR  514

Query  532  AKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSAL  591
            AK KI+QWFAKERREEA+E GK+A+ RE RR G+PLQRL++G++M+A+ARE+HY+DVSAL
Sbjct  515  AKAKIKQWFAKERREEAVEEGKEAITREARRTGMPLQRLISGDAMSALAREMHYSDVSAL  574

Query  592  YTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGAPG  651
            Y A+GE   SA+HVVQRL+A  GG ++AEEELAER+TP+T+ R  R + + GV V    G
Sbjct  575  YAAVGEHQASAQHVVQRLVAWFGGEEEAEEELAERATPSTV-RHRRPSGNAGVVVQDGDG  633

Query  652  -----VLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPS  706
                 +  KLA+CCTPVPGD I+GFVTRGGG+SVHRTDCTNA  L  + ER+++V W+ S
Sbjct  634  HEMGDLYVKLARCCTPVPGDEILGFVTRGGGISVHRTDCTNAGDLTAREERLVDVAWSVS  693

Query  707  PSSVFLVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKH  766
            P SVFLVAIQVEALDRHRLLSDVT+ LADEKVNILSAS TTS DRVA+SRF+FEMGDPKH
Sbjct  694  PESVFLVAIQVEALDRHRLLSDVTKVLADEKVNILSASTTTSRDRVAVSRFSFEMGDPKH  753

Query  767  LGHLLNAVRNVEGVYDVYRVTSAA  790
            LGHLL AVRN+EGVYDVYRVTSAA
Sbjct  754  LGHLLQAVRNIEGVYDVYRVTSAA  777


>gi|319947807|ref|ZP_08022001.1| GTP diphosphokinase [Dietzia cinnamea P4]
 gi|319438531|gb|EFV93457.1| GTP diphosphokinase [Dietzia cinnamea P4]
Length=788

 Score = 1109 bits (2868),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 538/733 (74%), Positives = 618/733 (85%), Gaps = 7/733 (0%)

Query  58   STTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLAVANILA  117
            ++T  VLEPLV VHR  + KAD+ +L RAY +A+++H    R+SGDPYITHPLAVA I A
Sbjct  59   TSTPAVLEPLVRVHRIHHAKADVGLLARAYTLAERQHEGVYRKSGDPYITHPLAVATICA  118

Query  118  ELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSAAEGETI  177
            E+GMDTTTLVAALLHDTVEDT Y+LE L  ++G EV HLVDGVTKLD+V  G AAE ETI
Sbjct  119  EMGMDTTTLVAALLHDTVEDTDYSLEQLEADYGGEVAHLVDGVTKLDKVDFGEAAEAETI  178

Query  178  RKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVK  237
            RKMI AMA DPRVLVIKVADRLHNMRTMRFLPPEKQ +KARETLEVIAPLAHRLGMA+VK
Sbjct  179  RKMIIAMAHDPRVLVIKVADRLHNMRTMRFLPPEKQVKKARETLEVIAPLAHRLGMATVK  238

Query  238  WELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATVEGRPKH  297
            WELEDL+FAIL PKKY+EIVRLVA RAPSRD YL  V   +   L  + I+A VEGRPKH
Sbjct  239  WELEDLAFAILEPKKYQEIVRLVADRAPSRDVYLNTVINRVKADLEKANIQARVEGRPKH  298

Query  298  YWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPR  357
            YWSIYQKMIV+GR+FD+IHDLVG+R+LCD++RDCYAA+GVVHS W+PM GRFKDYIAQPR
Sbjct  299  YWSIYQKMIVRGREFDEIHDLVGIRVLCDDVRDCYAAIGVVHSTWKPMPGRFKDYIAQPR  358

Query  358  YGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVLHPHAAAEI  417
            +GVY+SLHTTV+GP+GKPLE+QIRT +MHR AEYGIAAHWRYKE +G+    H    AE+
Sbjct  359  FGVYRSLHTTVIGPDGKPLEIQIRTHEMHRNAEYGIAAHWRYKETRGK----HNGDPAEV  414

Query  418  DDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPVDFAYAV  477
            D+MAWMRQLL WQREAADPGEFL+SLR+++  +EIFVFTPKGDVI LP G+TPVDFAYAV
Sbjct  415  DEMAWMRQLLSWQREAADPGEFLDSLRFEMTSKEIFVFTPKGDVINLPVGATPVDFAYAV  474

Query  478  HTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVSPRAKTKIR  537
            HTEVGHRCIGARVNG+LVALER LENGEVVEVFTSK PNAGPS DWQ+FVVS RAK+ IR
Sbjct  475  HTEVGHRCIGARVNGKLVALERPLENGEVVEVFTSKDPNAGPSLDWQKFVVSGRAKSSIR  534

Query  538  QWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVSALYTAIGE  597
            QWFAKERREEALE GKD + REVRRGG+P+ R+ + ES+A VAREL + DV+ALYTAIGE
Sbjct  535  QWFAKERREEALERGKDLITREVRRGGVPVHRVFSNESIAGVARELGFTDVTALYTAIGE  594

Query  598  GHVSAKHVVQRLLAELGGIDQAEEELAERSTPATM-PRRPRSTDDVGVSVPGAPGVLTKL  656
             HVSAK VV RL+A  GG+D+  EELA+RS   T+ P RP +    GV V G   V  KL
Sbjct  595  NHVSAKTVVGRLVAAHGGVDEVTEELADRSRDKTITPHRP-TPAGAGVLVGGVEDVHAKL  653

Query  657  AKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSSVFLVAIQ  716
            A+CCTPVPGD ++GF+TRGG VSVHRTDCTNA  L ++ ER+++V W P P ++FLVAIQ
Sbjct  654  ARCCTPVPGDEVLGFITRGGTVSVHRTDCTNAKDLHREPERLVKVEWTPQPGALFLVAIQ  713

Query  717  VEALDRHRLLSDVTRALADEKVNILSASVTTSG-DRVAISRFTFEMGDPKHLGHLLNAVR  775
            VEALDRHRLLSDVT+ LADEKVNILSASV T+G DRVAISRFTFEM DPKHLGH+LNAVR
Sbjct  714  VEALDRHRLLSDVTKVLADEKVNILSASVQTAGDDRVAISRFTFEMADPKHLGHVLNAVR  773

Query  776  NVEGVYDVYRVTS  788
             VEGV+D YR+TS
Sbjct  774  RVEGVFDAYRMTS  786


>gi|258653541|ref|YP_003202697.1| (p)ppGpp synthetase I SpoT/RelA [Nakamurella multipartita DSM 
44233]
 gi|258556766|gb|ACV79708.1| (p)ppGpp synthetase I, SpoT/RelA [Nakamurella multipartita DSM 
44233]
Length=822

 Score = 1085 bits (2807),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 516/740 (70%), Positives = 615/740 (84%), Gaps = 7/740 (0%)

Query  53   MTAQRSTTNP---VLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHP  109
            M+ QR T +P   VLEPL AVHR ++PKADL  LQRAYEVA+Q HA Q R+SGDPYITHP
Sbjct  87   MSGQRPTASPTRTVLEPLFAVHRSLHPKADLKELQRAYEVAEQAHAGQFRRSGDPYITHP  146

Query  110  LAVANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLG  169
            LAVA ILA+LGMDTTTLVAALLHDTVEDT YTLE +T +FG+EV HLVDGVTKLD+V  G
Sbjct  147  LAVATILADLGMDTTTLVAALLHDTVEDTEYTLEKVTADFGDEVAHLVDGVTKLDKVRFG  206

Query  170  SAAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAH  229
             A E ETIRKMI AMA DPRVLV+K+ADRLHNMRTMRFLPP+KQARKARETLEV+APLAH
Sbjct  207  DATEAETIRKMIIAMAEDPRVLVVKLADRLHNMRTMRFLPPDKQARKARETLEVLAPLAH  266

Query  230  RLGMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKA  289
            RLGMA++KWELEDL+F+ILH K+Y+EIVRLVA RAPSRDTYLA V  ++   LTA+KI  
Sbjct  267  RLGMATIKWELEDLAFSILHSKRYDEIVRLVADRAPSRDTYLAAVTQQLEAELTAAKIPG  326

Query  290  TVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRF  349
             V GR KHY+SIYQKM  +GR+FD+IHDLV VRIL   +R+CYAA+GVVH+LW PM GRF
Sbjct  327  QVVGRGKHYYSIYQKMKARGREFDEIHDLVAVRILVGSVRECYAAMGVVHALWAPMPGRF  386

Query  350  KDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVL  409
            KDYIAQPRYGVYQSLHTTV+GPEGKPLEVQIRT DMH TAEYGIAAHWRYKE +G     
Sbjct  387  KDYIAQPRYGVYQSLHTTVIGPEGKPLEVQIRTFDMHHTAEYGIAAHWRYKETRG----T  442

Query  410  HPHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGST  469
            H  A+A +D+MAWMRQLLDWQRE  D GEFL++LRY++A  EIFVFTPKGD+ TLP GST
Sbjct  443  HAGASATVDEMAWMRQLLDWQRETGDAGEFLDNLRYEMAHSEIFVFTPKGDIHTLPVGST  502

Query  470  PVDFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQFVVS  529
            PVDFAY+VHTEVGHRCIGA+V+GRLV LER+L NG+ VE+FTSKAPN GPSRDW  FV S
Sbjct  503  PVDFAYSVHTEVGHRCIGAKVDGRLVPLERRLSNGQFVEIFTSKAPNQGPSRDWLSFVAS  562

Query  530  PRAKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYADVS  589
             RAK+KIRQ+FAK RREEA+E GK+A+A+  RR GLP+QRLV  +++A V  EL Y D++
Sbjct  563  SRAKSKIRQYFAKSRREEAVELGKEALAKAARRAGLPVQRLVTHDALAVVGHELGYKDIA  622

Query  590  ALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRSTDDVGVSVPGA  649
            +LY A+GE HV+A  +V ++++ +GG + A +E+ +RS P+   RR R+T D GV V G 
Sbjct  623  SLYAAVGENHVAASTLVAKVVSYVGGEEDAVDEVTDRSVPSVTRRRHRATGDGGVLVKGI  682

Query  650  PGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAPSPSS  709
              +  KLA+CCTPVPGD I+GF+T+GG VSVHR DCTNA++LQ++  R++EV W PS ++
Sbjct  683  SDIQVKLARCCTPVPGDEILGFITKGGAVSVHRIDCTNASALQKEQARLVEVSWDPSSAT  742

Query  710  VFLVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGH  769
            VFLV IQVEALDR RLLSD+T+ LAD KVNILSA+++ S D +AISRF+FEM DP HLGH
Sbjct  743  VFLVTIQVEALDRARLLSDITKTLADLKVNILSANLSMSKDGMAISRFSFEMADPTHLGH  802

Query  770  LLNAVRNVEGVYDVYRVTSA  789
            L++AV+NV+GVYDVYRVTSA
Sbjct  803  LVHAVKNVDGVYDVYRVTSA  822


>gi|213966136|ref|ZP_03394323.1| RelA/SpoT family protein [Corynebacterium amycolatum SK46]
 gi|213951234|gb|EEB62629.1| RelA/SpoT family protein [Corynebacterium amycolatum SK46]
Length=753

 Score = 1079 bits (2790),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 517/751 (69%), Positives = 608/751 (81%), Gaps = 7/751 (0%)

Query  42   SRRVRARLARRMTAQRSTTNPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQS  101
            +RR  ARLAR +T  R+   PVL+PLVAVHR+++P+ADL++LQRAY+ A++ H    R+S
Sbjct  6    ARRYGARLARSLTGNRTKIRPVLDPLVAVHRQVHPRADLAVLQRAYDTAERLHDGVYRKS  65

Query  102  GDPYITHPLAVANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVT  161
            G+PYITHPLAVA I AE+GMDTTTLVAALLHDTVEDT YTLE L  +FG EV  LVDGVT
Sbjct  66   GEPYITHPLAVATIAAEIGMDTTTLVAALLHDTVEDTDYTLEDLERDFGPEVARLVDGVT  125

Query  162  KLDRVVLGSAAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETL  221
            KLD+V LGSAAE ET+RKMI AM++DPRVLVIKVADRLHNMRTMRFLPPEKQA+KARETL
Sbjct  126  KLDKVALGSAAEAETVRKMIIAMSQDPRVLVIKVADRLHNMRTMRFLPPEKQAKKARETL  185

Query  222  EVIAPLAHRLGMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNT  281
            EVIAPLAHRLGMASVKWELEDLSFAIL+PKKY+EIVRLVA RAP RD Y+ +V   I   
Sbjct  186  EVIAPLAHRLGMASVKWELEDLSFAILYPKKYDEIVRLVADRAPQRDRYIQEVSEMIQKD  245

Query  282  LTASKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSL  341
            L  S I A V+GRPKHYWSIYQKMIV+G +FD+I DLVG+R+L D  +DCYAA+G VHSL
Sbjct  246  LKESHIAAEVQGRPKHYWSIYQKMIVRGHEFDEIFDLVGLRVLVDTTKDCYAAMGAVHSL  305

Query  342  WQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKE  401
            ++PM GRFKDYI+ PR+GVYQSLHTTV+GP G PLEVQIRT +MH  AEYGIAAHWRYKE
Sbjct  306  FKPMPGRFKDYISAPRFGVYQSLHTTVIGPGGSPLEVQIRTHEMHYNAEYGIAAHWRYKE  365

Query  402  AKGRNGVLHPHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDV  461
             KG     H   +AE+D MAWMRQLLDWQREAADP EFL+SLRYDL+V EIF FTPKGDV
Sbjct  366  TKGS----HKGDSAEVDQMAWMRQLLDWQREAADPNEFLDSLRYDLSVTEIFAFTPKGDV  421

Query  462  ITLPTGSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSR  521
            ITLP  STPVDFAYAVHTEVGHRCIGA+VNG+LVALE  L+ G+ VE+FTSK  ++GPS+
Sbjct  422  ITLPADSTPVDFAYAVHTEVGHRCIGAKVNGKLVALESPLKTGDRVEIFTSKDAHSGPSK  481

Query  522  DWQQFVVSPRAKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVAR  581
            DW++FV +PRA+ KIRQWFAKERREEAL+ G+DA+A EV+RGGLP+ RL    S+  +A 
Sbjct  482  DWEKFVKTPRARAKIRQWFAKERREEALDAGRDALAAEVQRGGLPMHRLFTPASIKQIAS  541

Query  582  ELHYADVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMP--RRPRST  639
            ELHYADV ALYTAIG+G VSA+HV  RL+A+    D AEE+L  R+  + M     PR  
Sbjct  542  ELHYADVDALYTAIGKGQVSAQHVTHRLMAQFSSTDDAEEQLVSRTPISKMNVHNTPRRA  601

Query  640  DDVGVSVPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERII  699
            D  GV V G+  +  KLAKCCTPVPGD I GFVTRGGGVSVHRTDCTNA  L Q+ ERII
Sbjct  602  DSTGVLVEGSADMAAKLAKCCTPVPGDAIFGFVTRGGGVSVHRTDCTNAEKLHQEPERII  661

Query  700  EVLWAPSPS-SVFLVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFT  758
            EV WA   S +VF+V +Q+EALDRH LLS++TR  +D+KV+ILS S  TS DRVA+ RF+
Sbjct  662  EVSWATDSSGAVFMVTVQIEALDRHGLLSEITRVFSDQKVSILSTSSHTSDDRVAVMRFS  721

Query  759  FEMGDPKHLGHLLNAVRNVEGVYDVYRVTSA  789
            FE+ D K +G++ N +R VEGV+DVYR+TS 
Sbjct  722  FEVSDTKQMGYIFNILRGVEGVFDVYRITSG  752


>gi|284991594|ref|YP_003410148.1| (p)ppGpp synthetase I SpoT/RelA [Geodermatophilus obscurus DSM 
43160]
 gi|284064839|gb|ADB75777.1| (p)ppGpp synthetase I, SpoT/RelA [Geodermatophilus obscurus DSM 
43160]
Length=861

 Score = 1071 bits (2771),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 513/743 (70%), Positives = 616/743 (83%), Gaps = 7/743 (0%)

Query  53   MTAQRSTT-NPVLEPLVAVHREIYPKADLSILQRAYEVADQRHASQLRQSGDPYITHPLA  111
            +  QRST   PVLEPL  +HR+ +PKADL++LQRAY+VA+  HA+Q R+SGDPYITHPLA
Sbjct  119  VAGQRSTVVRPVLEPLAVLHRQSHPKADLALLQRAYDVAEAAHATQKRKSGDPYITHPLA  178

Query  112  VANILAELGMDTTTLVAALLHDTVEDTGYTLEALTEEFGEEVGHLVDGVTKLDRVVLGSA  171
            VA ILA LGMDTTTLVAALLHDTVEDTG TLE++ E FG EV HLVDGVTK+DRV LG A
Sbjct  179  VATILAGLGMDTTTLVAALLHDTVEDTGQTLESIREAFGPEVAHLVDGVTKIDRVKLGDA  238

Query  172  AEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRL  231
            A+ ETIRKMI AMARDPRVLVIK+ADRLHNMRT+RFLPPEKQ RKARETLE++APLAHRL
Sbjct  239  AQAETIRKMIVAMARDPRVLVIKLADRLHNMRTLRFLPPEKQERKARETLEILAPLAHRL  298

Query  232  GMASVKWELEDLSFAILHPKKYEEIVRLVAGRAPSRDTYLAKVRAEIVNTLTASKIKATV  291
            GM ++KWELEDL+FA L+PK+Y+EIVRLVA RAPSRDTYLA+V A + + L A+ I A V
Sbjct  299  GMNTIKWELEDLAFATLYPKRYDEIVRLVAERAPSRDTYLAEVTAAVTDQLKAAGIPAVV  358

Query  292  EGRPKHYWSIYQKMIVKGRDFDDIHDLVGVRILCDEIRDCYAAVGVVHSLWQPMAGRFKD  351
             GRPKHY+SIYQKMIV+GRDF DI DLVG+RIL D +RDCYAA+G++H+ WQP+ GRFKD
Sbjct  359  TGRPKHYYSIYQKMIVRGRDFTDIWDLVGIRILVDSVRDCYAALGIMHAHWQPVPGRFKD  418

Query  352  YIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKE-----AKGRN  406
            ++A P++ +YQSLHTTV+GP+GKP+E+QIRT DMHRTAEYGIAAHW+YKE      K  +
Sbjct  419  FVAMPKFNMYQSLHTTVIGPQGKPVELQIRTHDMHRTAEYGIAAHWKYKEKARPGGKTGD  478

Query  407  GVLHPHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPT  466
            G          DDM W+RQLLDWQREA +PGEFLE+LRYDL  QE+FVFTPKGDV++LP 
Sbjct  479  GGSRGAKTGSPDDMLWLRQLLDWQREAQEPGEFLETLRYDLGPQEVFVFTPKGDVVSLPG  538

Query  467  GSTPVDFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAPNAGPSRDWQQF  526
             +TPVDFAYAVHTEVGHRCIGARVNG LV+L+ KL NG+VVE+FTSK+P AGPS+DW  F
Sbjct  539  NATPVDFAYAVHTEVGHRCIGARVNGTLVSLDSKLGNGDVVEIFTSKSPTAGPSQDWLAF  598

Query  527  VVSPRAKTKIRQWFAKERREEALETGKDAMAREVRRGGLPLQRLVNGESMAAVARELHYA  586
            V S RA+TKIRQWF KERRE+A+E GK+A+ R +R+ GLPLQRL+  +++A +A++L YA
Sbjct  599  VGSSRARTKIRQWFTKERREDAVEAGKEALTRAMRKAGLPLQRLLRDDALATLAKDLRYA  658

Query  587  DVSALYTAIGEGHVSAKHVVQRLLAELGGIDQAEEELAERSTPATMPRRPRST-DDVGVS  645
            DV+ALY A+GE  +SA  +V++L+A LGG + A E++AE + P   P   RS+  D G+ 
Sbjct  659  DVTALYAAVGENQISASSIVEKLIAALGGTEGAVEDIAETTIPMRRPVHRRSSGGDPGIV  718

Query  646  VPGAPGVLTKLAKCCTPVPGDVIMGFVTRGGGVSVHRTDCTNAASLQQQAERIIEVLWAP  705
            V G   V  KLAKCCTPVPGD ++GFVTRGGGVSVHRTDCTNAA L+++ ER++EV WA 
Sbjct  719  VHGMTDVWAKLAKCCTPVPGDAVLGFVTRGGGVSVHRTDCTNAADLERKPERLVEVEWAS  778

Query  706  SPSSVFLVAIQVEALDRHRLLSDVTRALADEKVNILSASVTTSGDRVAISRFTFEMGDPK  765
             P SVFLVAIQVEALDRHRLLSDVT+ALADE+VNILSASV TS DRVA+SRFTFE+ DP 
Sbjct  779  QPGSVFLVAIQVEALDRHRLLSDVTKALADERVNILSASVQTSRDRVAVSRFTFELADPA  838

Query  766  HLGHLLNAVRNVEGVYDVYRVTS  788
            HLG +L  VRNV+GV+DV RVT+
Sbjct  839  HLGAVLQTVRNVDGVFDVERVTA  861



Lambda     K      H
   0.318    0.133    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 1904101588008


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40