BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2651c

Length=177
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|306794139|ref|ZP_07432441.1|  phiRv2 phage protease [Mycobacte...   346    7e-94
gi|15609788|ref|NP_217167.1|  phiRv2 prophage protease [Mycobacte...   346    8e-94
gi|167967167|ref|ZP_02549444.1|  hypothetical phiRv2 prophage pro...   343    4e-93
gi|289758779|ref|ZP_06518157.1|  phiRv2 prophage protease [Mycoba...   341    2e-92
gi|289751275|ref|ZP_06510653.1|  phiRv1 phage protein [Mycobacter...   323    4e-87
gi|289762823|ref|ZP_06522201.1|  conserved hypothetical protein [...   319    1e-85
gi|254366077|ref|ZP_04982122.1|  hypothetical protein TBHG_03409 ...   316    1e-84
gi|308376129|ref|ZP_07446149.2|  phage prohead protease, HK97 fam...   315    2e-84
gi|339295522|gb|AEJ47633.1|  phiRv2 prophage protease [Mycobacter...   311    2e-83
gi|15608715|ref|NP_216093.1|  phiRv1 phage protein [Mycobacterium...   303    8e-81
gi|240172572|ref|ZP_04751231.1|  phiRv2 prophage protease [Mycoba...   271    2e-71
gi|289753664|ref|ZP_06513042.1|  phiRv1 phage protein [Mycobacter...   267    5e-70
gi|289569613|ref|ZP_06449840.1|  conserved hypothetical protein [...   212    2e-53
gi|289447186|ref|ZP_06436930.1|  LOW QUALITY PROTEIN: phiRv1 phag...   197    7e-49
gi|226366385|ref|YP_002784168.1|  hypothetical protein ROP_69760 ...  90.9    7e-17
gi|239622571|ref|ZP_04665602.1|  predicted protein [Bifidobacteri...  71.6    4e-11
gi|23464973|ref|NP_695576.1|  hypothetical protein BL0376 [Bifido...  71.2    6e-11
gi|68171346|ref|ZP_00544743.1|  Peptidase U35, phage prohead HK97...  70.9    7e-11
gi|169829600|ref|YP_001699758.1|  major capsid protein [Lysinibac...  70.1    1e-10
gi|302875282|ref|YP_003843915.1|  phage prohead protease, HK97 fa...  69.7    2e-10
gi|306818206|ref|ZP_07451937.1|  conserved hypothetical protein [...  68.6    3e-10
gi|160940773|ref|ZP_02088115.1|  hypothetical protein CLOBOL_0566...  68.2    4e-10
gi|237794639|ref|YP_002862191.1|  caudovirus prohead protease [Cl...  68.2    4e-10
gi|288871067|ref|ZP_06116222.2|  peptidase U35, phage prohead HK9...  67.8    6e-10
gi|92116966|ref|YP_576695.1|  peptidase U35, phage prohead HK97 [...  66.6    1e-09
gi|304393575|ref|ZP_07375503.1|  HK97 family phage prohead protea...  65.5    3e-09
gi|344923094|ref|ZP_08776555.1|  HK97 family phage prohead protea...  64.7    5e-09
gi|168495135|ref|YP_001686873.1|  phage head maturation protease ...  64.7    5e-09
gi|338739213|ref|YP_004676175.1|  Phage prohead protease, HK97 fa...  64.7    6e-09
gi|190150089|ref|YP_001968614.1|  prohead protease (GP4) [Actinob...  64.3    7e-09
gi|338973923|ref|ZP_08629285.1|  HK97 family phage prohead protea...  63.9    8e-09
gi|303251433|ref|ZP_07337609.1|  Putative prohead protease (GP4) ...  63.2    2e-08
gi|154247633|ref|YP_001418591.1|  HK97 family phage prohead prote...  62.8    2e-08
gi|300022634|ref|YP_003755245.1|  phage prohead protease HK97 fam...  62.8    2e-08
gi|298290715|ref|YP_003692654.1|  phage prohead protease HK97 fam...  62.4    2e-08
gi|192290487|ref|YP_001991092.1|  phage prohead protease, HK97 fa...  62.4    2e-08
gi|92117265|ref|YP_576994.1|  peptidase U35, phage prohead HK97 [...  62.4    3e-08
gi|163759071|ref|ZP_02166157.1|  protease, putative [Hoeflea phot...  62.4    3e-08
gi|171741106|ref|ZP_02916913.1|  hypothetical protein BIFDEN_0017...  62.0    3e-08
gi|163737523|ref|ZP_02144940.1|  phage prohead protease, HK97 fam...  62.0    3e-08
gi|326385264|ref|ZP_08206927.1|  hypothetical protein SCNU_20062 ...  61.6    4e-08
gi|39934956|ref|NP_947232.1|  phage protease [Rhodopseudomonas pa...  61.6    5e-08
gi|317120887|ref|YP_004100890.1|  phage prohead protease HK97 fam...  61.2    5e-08
gi|30263664|ref|NP_846041.1|  prophage LambdaBa01, prohead protea...  61.2    5e-08
gi|167762229|ref|ZP_02434356.1|  hypothetical protein BACSTE_0058...  61.2    5e-08
gi|65320987|ref|ZP_00393946.1|  COG3740: Phage head maturation pr...  61.2    5e-08
gi|163941346|ref|YP_001646230.1|  HK97 family phage prohead prote...  61.2    6e-08
gi|265983715|ref|ZP_06096450.1|  protease [Brucella sp. 83/13] >g...  61.2    6e-08
gi|261213603|ref|ZP_05927884.1|  phage prohead protease [Brucella...  61.2    6e-08
gi|294851958|ref|ZP_06792631.1|  HK97 family phage prohead protea...  60.8    7e-08


>gi|306794139|ref|ZP_07432441.1| phiRv2 phage protease [Mycobacterium tuberculosis SUMu005]
 gi|306798555|ref|ZP_07436857.1| phiRv2 phage protease [Mycobacterium tuberculosis SUMu006]
 gi|308371084|ref|ZP_07423780.2| phiRv2 phage protease [Mycobacterium tuberculosis SUMu003]
 18 more sequence titles
 Length=186

 Score =  346 bits (888),  Expect = 7e-94, Method: Compositional matrix adjust.
 Identities = 177/177 (100%), Positives = 177/177 (100%), Gaps = 0/177 (0%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60
            LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK
Sbjct  10   LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  69

Query  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120
            LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI
Sbjct  70   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  129

Query  121  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW
Sbjct  130  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  186


>gi|15609788|ref|NP_217167.1| phiRv2 prophage protease [Mycobacterium tuberculosis H37Rv]
 gi|15842191|ref|NP_337228.1| phage prohead protease, putative [Mycobacterium tuberculosis 
CDC1551]
 gi|148662493|ref|YP_001284016.1| putative phage prohead protease [Mycobacterium tuberculosis H37Ra]
 35 more sequence titles
 Length=177

 Score =  346 bits (887),  Expect = 8e-94, Method: Compositional matrix adjust.
 Identities = 176/177 (99%), Positives = 177/177 (100%), Gaps = 0/177 (0%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60
            +SSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK
Sbjct  1    MSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60

Query  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120
            LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI
Sbjct  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120

Query  121  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW
Sbjct  121  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177


>gi|167967167|ref|ZP_02549444.1| hypothetical phiRv2 prophage protease [Mycobacterium tuberculosis 
H37Ra]
Length=186

 Score =  343 bits (881),  Expect = 4e-93, Method: Compositional matrix adjust.
 Identities = 176/177 (99%), Positives = 176/177 (99%), Gaps = 0/177 (0%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60
            LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK
Sbjct  10   LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  69

Query  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120
             LVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI
Sbjct  70   RLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  129

Query  121  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW
Sbjct  130  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  186


>gi|289758779|ref|ZP_06518157.1| phiRv2 prophage protease [Mycobacterium tuberculosis T85]
 gi|289714343|gb|EFD78355.1| phiRv2 prophage protease [Mycobacterium tuberculosis T85]
Length=177

 Score =  341 bits (875),  Expect = 2e-92, Method: Compositional matrix adjust.
 Identities = 173/177 (98%), Positives = 175/177 (99%), Gaps = 0/177 (0%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60
            +SSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK
Sbjct  1    MSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60

Query  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120
            LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI
Sbjct  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120

Query  121  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSL  +RLALMDW
Sbjct  121  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLGRSRLALMDW  177


>gi|289751275|ref|ZP_06510653.1| phiRv1 phage protein [Mycobacterium tuberculosis T92]
 gi|289691862|gb|EFD59291.1| phiRv1 phage protein [Mycobacterium tuberculosis T92]
Length=170

 Score =  323 bits (829),  Expect = 4e-87, Method: Compositional matrix adjust.
 Identities = 164/169 (98%), Positives = 168/169 (99%), Gaps = 0/169 (0%)

Query  9    AELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDAR  68
            AELR GEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDAR
Sbjct  2    AELRSGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDAR  61

Query  69   TRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDV  128
            TRYPVGRAVELREEPHGLFGAFE+A+TPDGDEALANVKAGVVD+FSVGFRPIRDRREGDV
Sbjct  62   TRYPVGRAVELREEPHGLFGAFEIADTPDGDEALANVKAGVVDSFSVGFRPIRDRREGDV  121

Query  129  IVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            +VRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW
Sbjct  122  LVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  170


>gi|289762823|ref|ZP_06522201.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
 gi|289710329|gb|EFD74345.1| conserved hypothetical protein [Mycobacterium tuberculosis GM 
1503]
Length=179

 Score =  319 bits (817),  Expect = 1e-85, Method: Compositional matrix adjust.
 Identities = 163/164 (99%), Positives = 164/164 (100%), Gaps = 0/164 (0%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60
            LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK
Sbjct  8    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  67

Query  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120
            LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI
Sbjct  68   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  127

Query  121  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVS  164
            RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVV+
Sbjct  128  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVT  171


>gi|254366077|ref|ZP_04982122.1| hypothetical protein TBHG_03409 [Mycobacterium tuberculosis str. 
Haarlem]
 gi|134151590|gb|EBA43635.1| hypothetical protein TBHG_03409 [Mycobacterium tuberculosis str. 
Haarlem]
Length=186

 Score =  316 bits (809),  Expect = 1e-84, Method: Compositional matrix adjust.
 Identities = 159/177 (90%), Positives = 167/177 (95%), Gaps = 0/177 (0%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60
            LSSILFR AELR GEGRTV+G IVPY E TTVRD DGEF+EMFAPGAFRRSIAERGHKVK
Sbjct  10   LSSILFRMAELRSGEGRTVHGTIVPYNEATTVRDFDGEFQEMFAPGAFRRSIAERGHKVK  69

Query  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120
            LLVSHDARTRYPVGRAVELREEPHGLFGAFE+A+TPDGDEALANVKAGVVD+FSVGFRPI
Sbjct  70   LLVSHDARTRYPVGRAVELREEPHGLFGAFEIADTPDGDEALANVKAGVVDSFSVGFRPI  129

Query  121  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            RDRREGDV+VRVEAALLEVSLTGVPAY GAQIAGVRAESL VVSRS AEA L+L+DW
Sbjct  130  RDRREGDVLVRVEAALLEVSLTGVPAYSGAQIAGVRAESLTVVSRSTAEAWLSLLDW  186


>gi|308376129|ref|ZP_07446149.2| phage prohead protease, HK97 family [Mycobacterium tuberculosis 
SUMu007]
 gi|308344235|gb|EFP33086.1| phage prohead protease, HK97 family [Mycobacterium tuberculosis 
SUMu007]
Length=177

 Score =  315 bits (807),  Expect = 2e-84, Method: Compositional matrix adjust.
 Identities = 157/177 (89%), Positives = 167/177 (95%), Gaps = 0/177 (0%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60
            +SSILFR AELR GEGRTV+G IVPY E TTVRD DGEF+EMFAPGAFRRSIAERGHK+K
Sbjct  1    MSSILFRMAELRSGEGRTVHGTIVPYNEATTVRDFDGEFQEMFAPGAFRRSIAERGHKLK  60

Query  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120
            LLVSHDARTRYPVGRAVELREEPHGLFGAFE+A+TPDGDEALANVKAGVVD+FSVGFRPI
Sbjct  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFEIADTPDGDEALANVKAGVVDSFSVGFRPI  120

Query  121  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            RDRREGDV+VRVEAALLEVSLTGVPAY GAQIAGVRAESL VVSRS AEA L+L+DW
Sbjct  121  RDRREGDVLVRVEAALLEVSLTGVPAYSGAQIAGVRAESLTVVSRSTAEAWLSLLDW  177


>gi|339295522|gb|AEJ47633.1| phiRv2 prophage protease [Mycobacterium tuberculosis CCDC5079]
 gi|339299140|gb|AEJ51250.1| phiRv2 prophage protease [Mycobacterium tuberculosis CCDC5180]
Length=159

 Score =  311 bits (797),  Expect = 2e-83, Method: Compositional matrix adjust.
 Identities = 158/159 (99%), Positives = 159/159 (100%), Gaps = 0/159 (0%)

Query  19   VYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPVGRAVE  78
            +YGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPVGRAVE
Sbjct  1    MYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPVGRAVE  60

Query  79   LREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRVEAALLE  138
            LREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRVEAALLE
Sbjct  61   LREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRVEAALLE  120

Query  139  VSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            VSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW
Sbjct  121  VSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  159


>gi|15608715|ref|NP_216093.1| phiRv1 phage protein [Mycobacterium tuberculosis H37Rv]
 gi|15843071|ref|NP_338108.1| hypothetical protein MT3573.8 [Mycobacterium tuberculosis CDC1551]
 gi|31792763|ref|NP_855256.1| phiRv1 phage protein [Mycobacterium bovis AF2122/97]
 33 more sequence titles
 Length=170

 Score =  303 bits (775),  Expect = 8e-81, Method: Compositional matrix adjust.
 Identities = 151/169 (90%), Positives = 160/169 (95%), Gaps = 0/169 (0%)

Query  9    AELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDAR  68
            AELR GEGRTV+G IVPY E TTVRD DGEF+EMFAPGAFRRSIAERGHK+KLLVSHDAR
Sbjct  2    AELRSGEGRTVHGTIVPYNEATTVRDFDGEFQEMFAPGAFRRSIAERGHKLKLLVSHDAR  61

Query  69   TRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDV  128
            TRYPVGRAVELREEPHGLFGAFE+A+TPDGDEALANVKAGVVD+FSVGFRPIRDRREGDV
Sbjct  62   TRYPVGRAVELREEPHGLFGAFEIADTPDGDEALANVKAGVVDSFSVGFRPIRDRREGDV  121

Query  129  IVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            +VRVEAALLEVSLTGVPAY GAQIAGVRAESL VVSRS AEA L+L+DW
Sbjct  122  LVRVEAALLEVSLTGVPAYSGAQIAGVRAESLTVVSRSTAEAWLSLLDW  170


>gi|240172572|ref|ZP_04751231.1| phiRv2 prophage protease [Mycobacterium kansasii ATCC 12478]
Length=176

 Score =  271 bits (694),  Expect = 2e-71, Method: Compositional matrix adjust.
 Identities = 136/177 (77%), Positives = 156/177 (89%), Gaps = 1/177 (0%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60
            ++SIL+R AELR G GRTV+G +VPYGE  TVRD DGE+RE FAPGAF+RSIAERGHK+K
Sbjct  1    MTSILYRNAELRSGTGRTVFGTVVPYGEEITVRDFDGEYRERFAPGAFQRSIAERGHKLK  60

Query  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120
            LLVSHD+RTRYPVGRAVELREE  GLF AFE+ANT DGDEALANV+AGVVD+FSVGFRPI
Sbjct  61   LLVSHDSRTRYPVGRAVELREERFGLFAAFEIANTRDGDEALANVRAGVVDSFSVGFRPI  120

Query  121  RDRREGDVIVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            RDRRE  V+VRVEAALLEVSLTG+PAY  A+IAGVR+E L V+ RS+A AR+ L+DW
Sbjct  121  RDRRENGVVVRVEAALLEVSLTGIPAYPSAEIAGVRSEQL-VIPRSVALARIQLLDW  176


>gi|289753664|ref|ZP_06513042.1| phiRv1 phage protein [Mycobacterium tuberculosis EAS054]
 gi|289694251|gb|EFD61680.1| phiRv1 phage protein [Mycobacterium tuberculosis EAS054]
Length=150

 Score =  267 bits (682),  Expect = 5e-70, Method: Compositional matrix adjust.
 Identities = 132/146 (91%), Positives = 140/146 (96%), Gaps = 0/146 (0%)

Query  9    AELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDAR  68
            AELR GEGRTV+G IVPY E TTVRD DGEF+EMFAPGAFRRSIAERGHK+KLLVSHDAR
Sbjct  2    AELRSGEGRTVHGTIVPYNEATTVRDFDGEFQEMFAPGAFRRSIAERGHKLKLLVSHDAR  61

Query  69   TRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDV  128
            TRYPVGRAVELREEPHGLFGAFE+A+TPDGDEALANVKAGVVD+FSVGFRPIRDRREGDV
Sbjct  62   TRYPVGRAVELREEPHGLFGAFEIADTPDGDEALANVKAGVVDSFSVGFRPIRDRREGDV  121

Query  129  IVRVEAALLEVSLTGVPAYLGAQIAG  154
            +VRVEAALLEVSLTGVPAY GA+IAG
Sbjct  122  LVRVEAALLEVSLTGVPAYSGAKIAG  147


>gi|289569613|ref|ZP_06449840.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
 gi|289543367|gb|EFD47015.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
Length=159

 Score =  212 bits (540),  Expect = 2e-53, Method: Compositional matrix adjust.
 Identities = 109/145 (76%), Positives = 119/145 (83%), Gaps = 5/145 (3%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60
            +SSILFR AELR GEGRTV+G IVPY E TTVRD DGEF+EMFAPGAFRRSIAERGHK+K
Sbjct  1    MSSILFRMAELRSGEGRTVHGTIVPYNEATTVRDFDGEFQEMFAPGAFRRSIAERGHKLK  60

Query  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI  120
            LLVSHDARTRYPVGRAVELREEPHGLFGAFE+A+TPDGDEALANVKAGVVD+FSV    +
Sbjct  61   LLVSHDARTRYPVGRAVELREEPHGLFGAFEIADTPDGDEALANVKAGVVDSFSV----V  116

Query  121  RDRREGDVIVRVEAALLEVSLTGVP  145
             D R G V      A    ++ G P
Sbjct  117  SD-RSGTVAKGCAGARRSAAVRGFP  140


>gi|289447186|ref|ZP_06436930.1| LOW QUALITY PROTEIN: phiRv1 phage protein [Mycobacterium tuberculosis 
CPHL_A]
 gi|289420144|gb|EFD17345.1| LOW QUALITY PROTEIN: phiRv1 phage protein [Mycobacterium tuberculosis 
CPHL_A]
Length=109

 Score =  197 bits (500),  Expect = 7e-49, Method: Compositional matrix adjust.
 Identities = 99/109 (91%), Positives = 105/109 (97%), Gaps = 0/109 (0%)

Query  69   TRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDV  128
            TRYPVGRAVELREEPHGLFGAFE+A+TPDGDEALANVKAGVVD+FSVGFRPIRDRREGDV
Sbjct  1    TRYPVGRAVELREEPHGLFGAFEIADTPDGDEALANVKAGVVDSFSVGFRPIRDRREGDV  60

Query  129  IVRVEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALMDW  177
            +VRVEAALLEVSLTGVPAY GAQIAGVRAESL VVSRS AEA L+L+DW
Sbjct  61   LVRVEAALLEVSLTGVPAYSGAQIAGVRAESLTVVSRSTAEAWLSLLDW  109


>gi|226366385|ref|YP_002784168.1| hypothetical protein ROP_69760 [Rhodococcus opacus B4]
 gi|226244875|dbj|BAH55223.1| hypothetical protein [Rhodococcus opacus B4]
Length=505

 Score = 90.9 bits (224),  Expect = 7e-17, Method: Compositional matrix adjust.
 Identities = 61/148 (42%), Positives = 78/148 (53%), Gaps = 10/148 (6%)

Query  9    AELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDAR  68
            A +   E R V G+ VPYG+     DL G F+E    GAF  +       V LL  HD R
Sbjct  10   ARMSDVEMRQVTGLAVPYGQTI---DLGG-FQERVERGAFDTT-----KSVPLLWGHDHR  60

Query  69   TRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDV  128
               P+GR   +R+  HGL     L +T  G+     +KAG V  FS+GF P + R+EGDV
Sbjct  61   D-IPIGRVTAMRDTEHGLEIDAVLNDTDKGENVYRALKAGDVSKFSIGFIPTKSRKEGDV  119

Query  129  IVRVEAALLEVSLTGVPAYLGAQIAGVR  156
            IVR +A L EVS+   PAY  A +  VR
Sbjct  120  IVREKATLKEVSVVNFPAYTKASVTSVR  147


>gi|239622571|ref|ZP_04665602.1| predicted protein [Bifidobacterium longum subsp. infantis CCUG 
52486]
 gi|239514568|gb|EEQ54435.1| predicted protein [Bifidobacterium longum subsp. infantis CCUG 
52486]
Length=528

 Score = 71.6 bits (174),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 53/147 (37%), Positives = 74/147 (51%), Gaps = 13/147 (8%)

Query  14   GEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPV  73
            G+GRT+ GV VP+G+V    D+ GE RE F P     ++ E     KL   HD      +
Sbjct  19   GDGRTIEGVAVPFGDVI---DVWGE-RETFDPD----TVFEGLDSAKLYYQHDTL----I  66

Query  74   GRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGD-VIVRV  132
            G          GL     +A+T  G +A+A +  G +D+ SVGF PI DR++ D V  R 
Sbjct  67   GSITSGENREDGLHITARIADTQQGRDAVALLDEGALDSLSVGFVPIEDRKDKDGVTHRR  126

Query  133  EAALLEVSLTGVPAYLGAQIAGVRAES  159
            +  LLE SL   PAY  A++   R  +
Sbjct  127  KVRLLETSLVSWPAYENAKLTNHRNNN  153


>gi|23464973|ref|NP_695576.1| hypothetical protein BL0376 [Bifidobacterium longum NCC2705]
 gi|23325571|gb|AAN24212.1| hypothetical protein with similarity to putative maturation protease 
of prophage CP-9 33CE [Bifidobacterium longum NCC2705]
Length=524

 Score = 71.2 bits (173),  Expect = 6e-11, Method: Compositional matrix adjust.
 Identities = 58/166 (35%), Positives = 85/166 (52%), Gaps = 25/166 (15%)

Query  3    SILFRTAELR--PGEGRTVYGVIVPYGEVTTVRDLDGEFR---EMFAPGA-FRRSIAERG  56
            +I  +  ELR   G+G  + G+ VP+G+        G +R   E FAP   F  +     
Sbjct  7    TITVKGIELREDQGDGTRIEGIAVPFGQRI------GLWRGAAEEFAPDCDFGDTT----  56

Query  57   HKVKLLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVG  116
             + KL   HD      +G+      E  GL     +++T +G +A+  ++ GV+D+FSVG
Sbjct  57   -RTKLSRDHDRL----IGKVTNATREADGLHITASISDTAEGRDAVQLIRDGVLDSFSVG  111

Query  117  FRPIR--DRREGD--VIVRVEAALLEVSLTGVPAYLGAQIAGVRAE  158
            F P+    R EGD  V VR    LLEV++TG+PAY GA I G R +
Sbjct  112  FMPVTTDKRTEGDTSVYVRRAVKLLEVAVTGIPAYTGAAITGQRDQ  157


>gi|68171346|ref|ZP_00544743.1| Peptidase U35, phage prohead HK97 [Ehrlichia chaffeensis str. 
Sapulpa]
 gi|88657926|ref|YP_506865.1| HK97 family phage prohead protease [Ehrlichia chaffeensis str. 
Arkansas]
 gi|67999244|gb|EAM85897.1| Peptidase U35, phage prohead HK97 [Ehrlichia chaffeensis str. 
Sapulpa]
 gi|88599383|gb|ABD44852.1| phage prohead protease, HK97 family [Ehrlichia chaffeensis str. 
Arkansas]
Length=177

 Score = 70.9 bits (172),  Expect = 7e-11, Method: Compositional matrix adjust.
 Identities = 51/159 (33%), Positives = 80/159 (51%), Gaps = 14/159 (8%)

Query  21   GVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPVGRAVELR  80
            G    Y  V  + D   + + +  PGAF  S+ +  HK+KLL  H++    P+G    L 
Sbjct  19   GTFSGYASVFNIVD---KQKHIILPGAFSNSV-KNSHKIKLLWQHNSTE--PIGNITSLT  72

Query  81   EEPHGLF-GAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRV--EAALL  137
            E+  GL+  A  L +   G EA   +K G+++A S+G+  I D  +    VRV  + +L 
Sbjct  73   EDNIGLYITANLLLDLQKGKEAYLMIKNGIINALSIGYSIIDDYIDAKTGVRVLKKISLW  132

Query  138  EVSLTGVPAYLGAQIAGVR--AESLAVVSRSLAEARLAL  174
            EVSL   PA + +++  V+   E LA    S  +A+L L
Sbjct  133  EVSLVTFPANIYSKVTNVKDTHEDLAT---SFIKAKLTL  168


>gi|169829600|ref|YP_001699758.1| major capsid protein [Lysinibacillus sphaericus C3-41]
 gi|168994088|gb|ACA41628.1| major capsid protein [Lysinibacillus sphaericus C3-41]
Length=485

 Score = 70.1 bits (170),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 47/166 (29%), Positives = 84/166 (51%), Gaps = 16/166 (9%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVK  60
            + ++   T   + G G    G    +   T + D+   F+E+ APGAF+R++A  G+ V 
Sbjct  1    MKNVQITTRSKKEGNGNVAVGYAAVFNSPTDIGDM---FKEVIAPGAFKRALA-TGNDVC  56

Query  61   LLVSHD-----ARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSV  115
             L++H+      RT+      ++L E+ HGL    +L NT DG + +A ++ G +   S 
Sbjct  57   CLMNHNWEKILGRTK---SGTLKLEEDQHGLKFEVDLPNTTDGTDLIALMERGDISQCSF  113

Query  116  GFRPIRDRREGDVIVRV----EAALLEVSLTGVPAYLGAQIAGVRA  157
            GFR + +  +  V+  +    E  L EVS+  +PAY   +++  R+
Sbjct  114  GFRIVDESWDHSVVPSLRTIHEVELYEVSIVTIPAYEDTEVSLTRS  159


>gi|302875282|ref|YP_003843915.1| phage prohead protease, HK97 family [Clostridium cellulovorans 
743B]
 gi|307688133|ref|ZP_07630579.1| phage prohead protease, HK97 family protein [Clostridium cellulovorans 
743B]
 gi|302578139|gb|ADL52151.1| phage prohead protease, HK97 family [Clostridium cellulovorans 
743B]
Length=199

 Score = 69.7 bits (169),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 58/179 (33%), Positives = 82/179 (46%), Gaps = 17/179 (9%)

Query  10   ELRPGEGRTVYGVIVPYGEVTTVRDLDG-EFREMFAPGAFRRSIAERGHKVKLLVSHDAR  68
            E    E +T+ G  V Y   T +RD  G EF E  A GAF +S+  R  K   L +HD  
Sbjct  20   EFGESEKKTIGGYAVKYNSPTLMRDRWGDEFLEEIASGAFDKSLQNRNQKA--LWNHD--  75

Query  69   TRYPVGR----AVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRD--  122
            T  P+G      +    +  GL    +L N   G++A  +VK G VD  S GF  + D  
Sbjct  76   TSKPLGSVSAGTLRFNSDTSGLNYDIDLPNNTYGNDAYESVKRGDVDGSSFGFMCLNDVW  135

Query  123  ---RREGDVIVR---VEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARLALM  175
               + EG  I +   VEA L EVS    PAY  ++++    E+    ++   E R  L+
Sbjct  136  SKVQFEGREIYKRSIVEANLFEVSPCTFPAYDSSEMSCRSLETFKEETKKREELRKKLI  194


>gi|306818206|ref|ZP_07451937.1| conserved hypothetical protein [Mobiluncus mulieris ATCC 35239]
 gi|304649170|gb|EFM46464.1| conserved hypothetical protein [Mobiluncus mulieris ATCC 35239]
Length=524

 Score = 68.6 bits (166),  Expect = 3e-10, Method: Compositional matrix adjust.
 Identities = 56/148 (38%), Positives = 78/148 (53%), Gaps = 16/148 (10%)

Query  15   EGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPVG  74
            E R + G+ VPY + T + +    F E  APGA   ++ + G   KLL  H    R P+G
Sbjct  18   EEREIIGLGVPYDDETEIWE---GFFERIAPGAV--TVPKAG--CKLLAEH----RKPIG  66

Query  75   RAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPI--RDRREGDVIVR-  131
              VE R+ P G     ++ANTP GDEAL   +A V    S+GF+ +   D +  D I R 
Sbjct  67   -TVEGRDTPQGWKIIGKIANTPAGDEALELARAAVYTGLSIGFQALEYNDTQAEDGIHRE  125

Query  132  -VEAALLEVSLTGVPAYLGAQIAGVRAE  158
              +A ++EVSLT  PAY  A +  VR +
Sbjct  126  ITKALVMEVSLTPFPAYENATVEKVRQK  153


>gi|160940773|ref|ZP_02088115.1| hypothetical protein CLOBOL_05667 [Clostridium bolteae ATCC BAA-613]
 gi|158436293|gb|EDP14060.1| hypothetical protein CLOBOL_05667 [Clostridium bolteae ATCC BAA-613]
Length=234

 Score = 68.2 bits (165),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 46/122 (38%), Positives = 69/122 (57%), Gaps = 5/122 (4%)

Query  21   GVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPVGRAVELR  80
            G+   YG V    D  G+  E   PGAF +++AE   +VK+L  H+     P+GR VELR
Sbjct  20   GIFSGYGAVFENIDSGGDIIE---PGAFTKTLAEGWERVKVLALHND-CWLPIGRPVELR  75

Query  81   EEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRP-IRDRREGDVIVRVEAALLEV  139
            EEP+GLF + ++++T  G +    +K GV++  S+G+ P I D  E  +    E  L EV
Sbjct  76   EEPNGLFISGKISDTTMGRDVKVLLKDGVLNELSIGYDPIIFDYDENGIRHLREIKLWEV  135

Query  140  SL  141
            S+
Sbjct  136  SV  137


>gi|237794639|ref|YP_002862191.1| caudovirus prohead protease [Clostridium botulinum Ba4 str. 657]
 gi|229260425|gb|ACQ51458.1| caudovirus prohead protease [Clostridium botulinum Ba4 str. 657]
Length=217

 Score = 68.2 bits (165),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 51/182 (29%), Positives = 87/182 (48%), Gaps = 16/182 (8%)

Query  3    SILFRTAELRPGEGRTVYGVIVPYG-EVTTVRDLDGE-FREMFAPGAFRRSIAERGHKVK  60
            ++ FR+ +    E R++ G    +  E   ++D  G+ F E  +PGAF +++A++     
Sbjct  7    NLEFRSTDF---EKRSIEGYAAIFSDEYVKLKDRWGDSFYEKVSPGAFLKTLADKTRDKF  63

Query  61   LLVSHDARTRYPVGRA---VELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGF  117
            +L++HD      VGR    + L E+  GL    E+ NT DG++ L NV+ G++   S GF
Sbjct  64   MLINHDWNK--IVGRTNSNLSLEEDTKGLRFTLEVPNTSDGNDLLENVRLGLIKGCSFGF  121

Query  118  RPIRDRREGDVIVR-----VEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAEARL  172
              I  +   D          E  L EV+ T +PAY   +I   R+E   +  + + E   
Sbjct  122  NIINQKTRWDDEWNFYRDITEVDLFEVTATPLPAYSDTEI-NCRSELSNICIKEMREKEQ  180

Query  173  AL  174
             +
Sbjct  181  TI  182


>gi|288871067|ref|ZP_06116222.2| peptidase U35, phage prohead HK97 [Clostridium hathewayi DSM 
13479]
 gi|288864928|gb|EFC97226.1| peptidase U35, phage prohead HK97 [Clostridium hathewayi DSM 
13479]
Length=228

 Score = 67.8 bits (164),  Expect = 6e-10, Method: Compositional matrix adjust.
 Identities = 47/138 (35%), Positives = 75/138 (55%), Gaps = 5/138 (3%)

Query  21   GVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSHDARTRYPVGRAVELR  80
            G+   YG V    D  G+  E   PGAF +++AE   +VK+L  H+     P+GR +ELR
Sbjct  13   GIFSGYGAVFDNVDSGGDIIE---PGAFTKTLAEGWERVKILALHN-DCWLPIGRPIELR  68

Query  81   EEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRV-EAALLEV  139
            E+ +GLF + ++++T  G +    +K GV++  S+G+ PI    +GD I  + E  L EV
Sbjct  69   EDANGLFLSAKISDTSMGRDIKVLLKDGVLNELSIGYDPIVFDYDGDGIRHLREVKLWEV  128

Query  140  SLTGVPAYLGAQIAGVRA  157
            S+        A I G ++
Sbjct  129  SVVTWAMNPEAVITGYKS  146


>gi|92116966|ref|YP_576695.1| peptidase U35, phage prohead HK97 [Nitrobacter hamburgensis X14]
 gi|91799860|gb|ABE62235.1| prohead peptidase, Unknown type peptidase, MEROPS family U35 
[Nitrobacter hamburgensis X14]
Length=215

 Score = 66.6 bits (161),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 56/153 (37%), Positives = 78/153 (51%), Gaps = 18/153 (11%)

Query  14   GEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERG-HKVKLLVSHDARTRYP  72
            G+G TV G    +GE+   RD       M  PGAF +++  RG  KV +L  HD     P
Sbjct  15   GDG-TVEGYASLFGEIDQARD-------MVMPGAFAQTLKVRGLRKVPMLFQHDPSE--P  64

Query  73   VGRAVELREEPHGLFGAFELANTPD---GDEALANVKAGVVDAFSVGFRPIRDRREGDVI  129
            VG  +ELRE+  GL+    L   PD     E LA V+AG VD  S+G+R +R + E    
Sbjct  65   VGIWLELREDFRGLWARGRL--IPDVMRARELLALVEAGAVDGLSIGYRTVRGQIEPRTR  122

Query  130  VR--VEAALLEVSLTGVPAYLGAQIAGVRAESL  160
            VR   +  L E+S+   P   GA++  V+  +L
Sbjct  123  VRKLYQVDLWEISIVTFPLLAGARVRAVKQAAL  155


>gi|304393575|ref|ZP_07375503.1| HK97 family phage prohead protease [Ahrensia sp. R2A130]
 gi|303294582|gb|EFL88954.1| HK97 family phage prohead protease [Ahrensia sp. R2A130]
Length=223

 Score = 65.5 bits (158),  Expect = 3e-09, Method: Compositional matrix adjust.
 Identities = 42/116 (37%), Positives = 67/116 (58%), Gaps = 6/116 (5%)

Query  46   GAFRRSIAERG-HKVKLLVSHDARTRYPVGRAVELREEPHGLFGAFELA-NTPDGDEALA  103
            GAFR+S+  RG   V++L  HD  +  P+G  +++RE+  GL     +  +TP G E L 
Sbjct  43   GAFRKSLKVRGVAGVRMLYQHDPAS--PIGTWLDIREDAKGLLVKGRIVEDTPRGAEVLT  100

Query  104  NVKAGVVDAFSVGFRPIRDRREGDVIVR--VEAALLEVSLTGVPAYLGAQIAGVRA  157
             ++AG VD  S+GF+ IR +  G   VR  +EA L E+S+   P    A+++ V++
Sbjct  101  LMRAGAVDGLSIGFKTIRSKPAGQAGVRSILEADLWEISIVTFPMLPQARVSQVKS  156


>gi|344923094|ref|ZP_08776555.1| HK97 family phage prohead protease [Candidatus Odyssella thessalonicensis 
L13]
Length=183

 Score = 64.7 bits (156),  Expect = 5e-09, Method: Compositional matrix adjust.
 Identities = 55/160 (35%), Positives = 83/160 (52%), Gaps = 13/160 (8%)

Query  21   GVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAE---RGHKVKLLVSHDARTRYPVGRAV  77
            G    Y  V  V D     +E+ A  AF++S+ +   +G   K+L  HD R   P+G   
Sbjct  18   GFFCGYASVFEVTD---HHQEIVARRAFQQSLNKWRGKGRLPKMLWQHDQRR--PIGVWD  72

Query  78   ELREEPHGLF-GAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRV--EA  134
            E+ E+ HGLF     L +   G EA + +KAGV+D+ S+GF+P+R  ++     RV  E 
Sbjct  73   EIYEDEHGLFVKGRLLLDLAAGREAYSLLKAGVIDSLSIGFKPVRAIKDPKRNARVLEEV  132

Query  135  ALLEVSLTGVPAYLGAQIAGVR--AESLAVVSRSLAEARL  172
             LLE+SL    A   A+I  V+   E+ A+V +    +RL
Sbjct  133  DLLEISLVTFAANPDAKITTVKEFVENDAIVRQIKELSRL  172


>gi|168495135|ref|YP_001686873.1| phage head maturation protease [Azospirillum phage Cd]
 gi|168148894|emb|CAO99358.1| phage head maturation protease [Azospirillum phage Cd]
Length=229

 Score = 64.7 bits (156),  Expect = 5e-09, Method: Compositional matrix adjust.
 Identities = 47/142 (34%), Positives = 75/142 (53%), Gaps = 11/142 (7%)

Query  21   GVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAE---RGHKVKLLVSHDARTRYPVGRAV  77
            G++  YG V  ++D    + ++ APGAF+ S+A+   +G    +L  HD+    PVG   
Sbjct  30   GLVTGYGSVFGIKD---SYGDIVAPGAFKASLADWKAKGRMPAMLWQHDSSE--PVGMWT  84

Query  78   ELREEPHGLFGAFELANTPD-GDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRV--EA  134
            E+ E+  GL  + +L  T D G EA  ++KAG V   S+GF+ +      +   R   + 
Sbjct  85   EMEEDGIGLRCSGQLLLTVDKGKEAYEHLKAGTVGGLSIGFQTVERTWNYEEETRTLNKV  144

Query  135  ALLEVSLTGVPAYLGAQIAGVR  156
             L EVSL   PA   A+++GV+
Sbjct  145  NLWEVSLVTFPANDAARVSGVK  166


>gi|338739213|ref|YP_004676175.1| Phage prohead protease, HK97 family [Hyphomicrobium sp. MC1]
 gi|337759776|emb|CCB65607.1| Phage prohead protease, HK97 family [Hyphomicrobium sp. MC1]
Length=234

 Score = 64.7 bits (156),  Expect = 6e-09, Method: Compositional matrix adjust.
 Identities = 48/153 (32%), Positives = 76/153 (50%), Gaps = 9/153 (5%)

Query  21   GVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGH-KVKLLVSHDARTRYPVGRAVEL  79
            GV   Y  +    DL     ++ APGAFR S+  RG  ++K+L  HD     P+G   E+
Sbjct  30   GVFEGYASLFNREDLG---HDVIAPGAFRDSLLNRGAARIKMLFQHDPGE--PIGVWDEI  84

Query  80   REEPHGLFGAFELAN-TPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVR--VEAAL  136
            RE+  GL+    L        E  A ++AG +D  S+GF+ ++ RR+    VR   +  L
Sbjct  85   REDARGLYVRGRLMTAVAKAREVFALMRAGALDGLSIGFKAVKARRDASTGVRRLEKVDL  144

Query  137  LEVSLTGVPAYLGAQIAGVRAESLAVVSRSLAE  169
             E+S+   P   GA++  V+    AV + ++ E
Sbjct  145  WEISVVTFPMLPGARVESVKTRPFAVTAPTMRE  177


>gi|190150089|ref|YP_001968614.1| prohead protease (GP4) [Actinobacillus pleuropneumoniae serovar 
7 str. AP76]
 gi|307263422|ref|ZP_07545038.1| prohead protease (GP4) [Actinobacillus pleuropneumoniae serovar 
13 str. N273]
 gi|189915220|gb|ACE61472.1| Putative prohead protease (GP4) [Actinobacillus pleuropneumoniae 
serovar 7 str. AP76]
 gi|306871300|gb|EFN03028.1| prohead protease (GP4) [Actinobacillus pleuropneumoniae serovar 
13 str. N273]
Length=190

 Score = 64.3 bits (155),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 51/151 (34%), Positives = 75/151 (50%), Gaps = 16/151 (10%)

Query  7    RTAELR-PGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSH  65
            RTA L    E RT+ G +V + + + V  L GEF E FAP AF +S+   G  V+ L  H
Sbjct  9    RTASLAAEQESRTLSGYVVQWNKPSEV--LWGEFIETFAPNAFTKSL-NGGGDVRALFEH  65

Query  66   D-----ARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRP-  119
            D      RT       + L E+  GL    +L NT  G++ L +V+ G +   S GF P 
Sbjct  66   DYTKLLGRTS---SNTLTLAEDNQGLCFRIDLPNTQLGNDILESVRRGDISGMSFGFLPE  122

Query  120  ---IRDRREGDVIVRVEAALLEVSLTGVPAY  147
                 + +E  +    +A L E+++T +PAY
Sbjct  123  VEEWDETKEPALRTIKQAQLFEITVTSIPAY  153


>gi|338973923|ref|ZP_08629285.1| HK97 family phage prohead protease [Bradyrhizobiaceae bacterium 
SG-6C]
 gi|338232650|gb|EGP07778.1| HK97 family phage prohead protease [Bradyrhizobiaceae bacterium 
SG-6C]
Length=171

 Score = 63.9 bits (154),  Expect = 8e-09, Method: Compositional matrix adjust.
 Identities = 54/164 (33%), Positives = 81/164 (50%), Gaps = 21/164 (12%)

Query  18   TVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERG-HKVKLLVSHDARTRYPVGRA  76
             V G    +GE+   RD       M  PGAF +++A+RG  K+ +L  HD     PVG  
Sbjct  18   NVEGYASLFGEIDQARD-------MVMPGAFAKTLAQRGLRKIPMLFQHDPAE--PVGIW  68

Query  77   VELREEPHGLFGAFELANTPD---GDEALANVKAGVVDAFSVGFRPIRDRREGDVIVR--  131
            ++L E+  GL+    L   PD   G E  A V+ G +D  S+G+R +R + +    VR  
Sbjct  69   LDLHEDFRGLWARGRL--IPDVARGRELFALVEQGAIDGLSIGYRTVRGQIDPKTRVRKL  126

Query  132  VEAALLEVSLTGVPAYLGAQIAGVRAESLAVVS----RSLAEAR  171
             +  L EVS+   P   GA++  V+  + +  S    R+ AEAR
Sbjct  127  YQVDLWEVSIVTFPLLAGARVRAVKGRTPSQQSPARFRNHAEAR  170


>gi|303251433|ref|ZP_07337609.1| Putative prohead protease (GP4) [Actinobacillus pleuropneumoniae 
serovar 6 str. Femo]
 gi|307252331|ref|ZP_07534228.1| prohead protease (GP4) [Actinobacillus pleuropneumoniae serovar 
6 str. Femo]
 gi|307261241|ref|ZP_07542916.1| prohead protease (GP4) [Actinobacillus pleuropneumoniae serovar 
12 str. 1096]
 gi|302649665|gb|EFL79845.1| Putative prohead protease (GP4) [Actinobacillus pleuropneumoniae 
serovar 6 str. Femo]
 gi|306860253|gb|EFM92269.1| prohead protease (GP4) [Actinobacillus pleuropneumoniae serovar 
6 str. Femo]
 gi|306868972|gb|EFN00774.1| prohead protease (GP4) [Actinobacillus pleuropneumoniae serovar 
12 str. 1096]
Length=190

 Score = 63.2 bits (152),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 51/151 (34%), Positives = 75/151 (50%), Gaps = 16/151 (10%)

Query  7    RTAELR-PGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHKVKLLVSH  65
            RTA L    E RT+ G +V + + + V  L GEF E FAP AF +S+   G  V+ L  H
Sbjct  9    RTASLAAEQESRTLSGYVVQWNKPSEV--LWGEFIETFAPNAFTKSL-NGGGDVRALFEH  65

Query  66   D-----ARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRP-  119
            D      RT       + L E+  GL    +L NT  G++ L +V+ G +   S GF P 
Sbjct  66   DYTKLLGRTS---SNTLTLAEDNQGLRFRIDLPNTQLGNDILESVRRGDISGMSFGFLPE  122

Query  120  ---IRDRREGDVIVRVEAALLEVSLTGVPAY  147
                 + +E  +    +A L E+++T +PAY
Sbjct  123  VEEWDETKEPALRTIKQAQLFEITVTSIPAY  153


>gi|154247633|ref|YP_001418591.1| HK97 family phage prohead protease [Xanthobacter autotrophicus 
Py2]
 gi|154161718|gb|ABS68934.1| phage prohead protease, HK97 family [Xanthobacter autotrophicus 
Py2]
Length=371

 Score = 62.8 bits (151),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 54/151 (36%), Positives = 73/151 (49%), Gaps = 17/151 (11%)

Query  14   GEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIA---ERGHKVKLLVSHDARTR  70
            G+  T  G    +G V   RDL        A GAF  S++    +G   KLL  HDAR  
Sbjct  173  GDAGTFTGYGAAFGNVDQGRDL-------IARGAFADSLSAWRSKGKLPKLLWQHDARK-  224

Query  71   YPVGRAVELREEPHGLF--GAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDV  128
             P+G   E+RE+ +GLF  G F  A     DEA A +K G +D  S+G+  I D  +   
Sbjct  225  -PIGVWTEMREDDYGLFVKGRF-TAGVKQADEAYALLKDGALDGLSIGYATIEDEIDRAA  282

Query  129  IVR--VEAALLEVSLTGVPAYLGAQIAGVRA  157
             +R  V+  L+EVSL        A + GV+A
Sbjct  283  GIRKLVKLDLMEVSLVTFAMNPAAGVTGVKA  313


>gi|300022634|ref|YP_003755245.1| phage prohead protease HK97 family [Hyphomicrobium denitrificans 
ATCC 51888]
 gi|299524455|gb|ADJ22924.1| phage prohead protease, HK97 family [Hyphomicrobium denitrificans 
ATCC 51888]
Length=234

 Score = 62.8 bits (151),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 49/160 (31%), Positives = 80/160 (50%), Gaps = 10/160 (6%)

Query  13   PGEGRTVY-GVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGH-KVKLLVSHDARTR  70
            P E +++  GV   Y  +    DL     ++ APGAFR S+A RG  ++K+L  HD    
Sbjct  21   PFEAKSLDDGVFEGYASLFNREDLG---HDVIAPGAFRESLASRGAARIKMLFQHDPAE-  76

Query  71   YPVGRAVELREEPHGLFGAFELANT-PDGDEALANVKAGVVDAFSVGFRPIRDRREGDVI  129
             P+G   E+ E+  GL+    L        E LA ++AG +D  S+GF+ ++ RR+    
Sbjct  77   -PIGVWDEIHEDARGLYVRGRLMTAVSKAREVLALMRAGALDGLSIGFKTVKARRDAASG  135

Query  130  VR--VEAALLEVSLTGVPAYLGAQIAGVRAESLAVVSRSL  167
            VR   +  L E+S+   P   GA++  V+    A  + ++
Sbjct  136  VRRLEKIDLWEISVVTFPMLPGARVQSVKTRPFATAAPTM  175


>gi|298290715|ref|YP_003692654.1| phage prohead protease HK97 family [Starkeya novella DSM 506]
 gi|296927226|gb|ADH88035.1| phage prohead protease, HK97 family [Starkeya novella DSM 506]
Length=187

 Score = 62.4 bits (150),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 52/128 (41%), Positives = 69/128 (54%), Gaps = 9/128 (7%)

Query  40   REMFAPGAFRRSIAERGHK-VKLLVSHDARTRYPVGRAVELREEPHGLF--GAFELANTP  96
            R++  PGAF RS+AERG   V++L  HD     P+G  + LRE+  GL   G   L +  
Sbjct  42   RDLILPGAFARSLAERGTSGVRMLFQHDPAE--PIGTWLSLREDAVGLHVRGRLTL-DVA  98

Query  97   DGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVR--VEAALLEVSLTGVPAYLGAQIAG  154
               E LA ++AG +D  S+GFR +  R +    VR      L EVS+   P    A+IAG
Sbjct  99   RSREVLALMRAGAIDGLSIGFRTVEGRTDPRSRVRRLSRIDLWEVSIVTFPMQPDARIAG  158

Query  155  V-RAESLA  161
            V RA SLA
Sbjct  159  VKRAASLA  166


>gi|192290487|ref|YP_001991092.1| phage prohead protease, HK97 family [Rhodopseudomonas palustris 
TIE-1]
 gi|192284236|gb|ACF00617.1| phage prohead protease, HK97 family [Rhodopseudomonas palustris 
TIE-1]
Length=248

 Score = 62.4 bits (150),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 52/154 (34%), Positives = 77/154 (50%), Gaps = 17/154 (11%)

Query  9    AELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERG-HKVKLLVSHDA  67
            A L   E  ++ G    +GE+   RD       M  PGAF +++ +RG  K+ +L  HD 
Sbjct  19   ARLSLAEDGSIDGYASLFGEIDQARD-------MVMPGAFTQTLKQRGLRKIPMLFQHDP  71

Query  68   RTRYPVGRAVELREEPHGLFGAFELANTPD---GDEALANVKAGVVDAFSVGFRPIRDRR  124
                PVG  +EL E+  GL     L   PD   G E LA ++AG +D  S+G+R +R + 
Sbjct  72   AE--PVGVWLELAEDLRGLRARGRL--IPDVARGRELLALLRAGAIDGLSIGYRTVRGQI  127

Query  125  EGDVIVR--VEAALLEVSLTGVPAYLGAQIAGVR  156
            +    VR   +  L E+S+   P   GA+IA V+
Sbjct  128  DPKTRVRRLYQVDLWEISIVTFPLLAGARIATVK  161


>gi|92117265|ref|YP_576994.1| peptidase U35, phage prohead HK97 [Nitrobacter hamburgensis X14]
 gi|91800159|gb|ABE62534.1| prohead peptidase, Unknown type peptidase, MEROPS family U35 
[Nitrobacter hamburgensis X14]
Length=176

 Score = 62.4 bits (150),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 42/143 (30%), Positives = 72/143 (51%), Gaps = 9/143 (6%)

Query  21   GVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAER-GHKVKLLVSHDARTRYPVGRAVEL  79
            G    Y  V  V D     +++    AF++S+ +R   KVK+L  HD     P+G+ + L
Sbjct  20   GTFTGYASVFDVVD---SHKDIVVKSAFKKSLVKRPAAKVKMLREHDQTE--PIGKWLSL  74

Query  80   REEPHGLFGAFELA-NTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVRV--EAAL  136
             E+  GL    +L   T  G E    +KAG++D+ S+G+R +RDR +     R+  +  L
Sbjct  75   VEDDRGLKATGQLILGTTKGSETYKLMKAGLLDSLSIGYRTVRDRMDRTKGARILEQVDL  134

Query  137  LEVSLTGVPAYLGAQIAGVRAES  159
             E+S+   P+   + +  V++ S
Sbjct  135  WEISVVTFPSNTESTVTAVKSNS  157


>gi|163759071|ref|ZP_02166157.1| protease, putative [Hoeflea phototrophica DFL-43]
 gi|162283475|gb|EDQ33760.1| protease, putative [Hoeflea phototrophica DFL-43]
Length=241

 Score = 62.4 bits (150),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 42/122 (35%), Positives = 65/122 (54%), Gaps = 6/122 (4%)

Query  40   REMFAPGAFRRSIAERGH-KVKLLVSHDARTRYPVGRAVELREEPHGLFGAFELA-NTPD  97
            R+M  PGAF  S+  RG   V++L  HD     P+GR + +RE+ HGL    +L+     
Sbjct  52   RDMIEPGAFAASLRRRGAADVRMLYQHD--PDQPIGRWLSIREDSHGLHVEGKLSLGVAR  109

Query  98   GDEALANVKAGVVDAFSVGFRPIRDRREGDVIVR--VEAALLEVSLTGVPAYLGAQIAGV  155
              E    +K+G +D  S+GF+ +R R E    VR  + A L E+S+   P   GA++  V
Sbjct  110  AREVHELMKSGALDGLSIGFQTLRARNEAKSGVRRILSADLWEISVVTFPMQPGARVTAV  169

Query  156  RA  157
            ++
Sbjct  170  KS  171


>gi|171741106|ref|ZP_02916913.1| hypothetical protein BIFDEN_00173 [Bifidobacterium dentium ATCC 
27678]
 gi|171276720|gb|EDT44381.1| hypothetical protein BIFDEN_00173 [Bifidobacterium dentium ATCC 
27678]
Length=520

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 46/144 (32%), Positives = 68/144 (48%), Gaps = 15/144 (10%)

Query  15   EGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRR-SIAERGHKVKLLVSHDARTRYPV  73
            +GRT+ G+ VPYG+V    D          P  F R  + +   + KL   H       +
Sbjct  20   DGRTLEGIAVPYGDVIDTWD---------GPETFDRDCVFDDLDQAKLCYQHGE----VI  66

Query  74   GRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRRE-GDVIVRV  132
            GR +       GL     +++T  G +A+  V+ GV+D+FSVGF PI   R+   +  R 
Sbjct  67   GRIIGGESREDGLHITARVSDTAKGRDAVTLVRDGVLDSFSVGFIPIESERDKAGITHRR  126

Query  133  EAALLEVSLTGVPAYLGAQIAGVR  156
               LLE S+   PAY  A++ G R
Sbjct  127  RVRLLETSIVSWPAYQNARLTGQR  150


>gi|163737523|ref|ZP_02144940.1| phage prohead protease, HK97 family protein [Phaeobacter gallaeciensis 
BS107]
 gi|161389049|gb|EDQ13401.1| phage prohead protease, HK97 family protein [Phaeobacter gallaeciensis 
BS107]
Length=220

 Score = 62.0 bits (149),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 45/118 (39%), Positives = 65/118 (56%), Gaps = 7/118 (5%)

Query  41   EMFAPGAFRRSI---AERGHKVKLLVSHDARTRYPVGRAVELREEPHGLF-GAFELANTP  96
            ++ APGA+  S+   A +G KVK+L  HD    +P+G   ELRE+  GL+     L    
Sbjct  36   DIVAPGAYAASLSKLAAQGRKVKMLWQHD--PSHPIGVWEELREDDRGLWVKGRILTEVE  93

Query  97   DGDEALANVKAGVVDAFSVGFRPIRDRR-EGDVIVRVEAALLEVSLTGVPAYLGAQIA  153
             G EA+A +KAG +D  S+G+R I  ++ +G   V  E  L EVSL   P    A++A
Sbjct  94   KGREAVALIKAGSIDGLSIGYRTISAQKDDGGNRVLQEVDLWEVSLVTFPMLPTARVA  151


>gi|326385264|ref|ZP_08206927.1| hypothetical protein SCNU_20062 [Gordonia neofelifaecis NRRL 
B-59395]
 gi|326196007|gb|EGD53218.1| hypothetical protein SCNU_20062 [Gordonia neofelifaecis NRRL 
B-59395]
Length=657

 Score = 61.6 bits (148),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 49/147 (34%), Positives = 72/147 (49%), Gaps = 19/147 (12%)

Query  17   RTVYGVIVPYGE--VTTVRDLDGEFREMFAPGAFR--RSIAERGHKVKLLVSHDARTRY-  71
            R V G+++P+ +   TT   L         PGA R  R I     +VKLL  H     + 
Sbjct  133  RVVSGLVIPWNQQGATTAGAL------TIPPGAVRVPRDIG----RVKLLFKHTGTEGHK  182

Query  72   PVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVR  131
            PVGRA+    +  GL  +F +A TPDGD A+  V+ GV DAFS   R ++     +    
Sbjct  183  PVGRALSYEPKADGLHMSFAIARTPDGDAAIDQVREGVFDAFSAELRAVKK----NATTV  238

Query  132  VEAALLEVSLTGVPAYLGAQIAGVRAE  158
             ++ L  V+L   PA+  A++  + AE
Sbjct  239  QDSILTGVALVDRPAFDDARVHNLNAE  265


>gi|39934956|ref|NP_947232.1| phage protease [Rhodopseudomonas palustris CGA009]
 gi|39648807|emb|CAE27328.1| possible phage protease, R. capsulatus GTA orfg4 homologue [Rhodopseudomonas 
palustris CGA009]
Length=225

 Score = 61.6 bits (148),  Expect = 5e-08, Method: Compositional matrix adjust.
 Identities = 52/154 (34%), Positives = 77/154 (50%), Gaps = 17/154 (11%)

Query  9    AELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERG-HKVKLLVSHDA  67
            A L   E  ++ G    +GE+   RD       M  PGAF +++ +RG  K+ +L  HD 
Sbjct  19   ARLSLAEDGSIDGYASLFGEIDQARD-------MVMPGAFTQTLKQRGLRKIPMLFQHDP  71

Query  68   RTRYPVGRAVELREEPHGLFGAFELANTPD---GDEALANVKAGVVDAFSVGFRPIRDRR  124
                PVG  +EL E+  GL     L   PD   G E LA ++AG +D  S+G+R +R + 
Sbjct  72   AE--PVGVWLELAEDLRGLRARGRL--IPDVARGRELLALLRAGAIDGLSIGYRTVRGQI  127

Query  125  EGDVIVR--VEAALLEVSLTGVPAYLGAQIAGVR  156
            +    VR   +  L E+S+   P   GA+IA V+
Sbjct  128  DPRTRVRRLYQVDLWEISIVTFPLLSGARIATVK  161


>gi|317120887|ref|YP_004100890.1| phage prohead protease HK97 family [Thermaerobacter marianensis 
DSM 12885]
 gi|315590867|gb|ADU50163.1| phage prohead protease, HK97 family [Thermaerobacter marianensis 
DSM 12885]
Length=476

 Score = 61.2 bits (147),  Expect = 5e-08, Method: Compositional matrix adjust.
 Identities = 47/134 (36%), Positives = 66/134 (50%), Gaps = 10/134 (7%)

Query  30   TTVRDLDGEFREMFAPGAFRRSIAER--GHKVKLLVSHDARTRYPVGRAVELREEPHGLF  87
            T  RD DG+   +   GAF+++I ER    KVKLL SH   +++ +G  VE REE HGL+
Sbjct  33   TWDRDEDGD---VIVKGAFKKTIQERVPAGKVKLLDSHRWDSQHVLGTVVEAREEDHGLW  89

Query  88   GAFELANTPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVR-----VEAALLEVSLT  142
                 + + +       V  G + AFS+GF  +RD  + D   R      E  L EVS+ 
Sbjct  90   IKAIFSGSAEAQAVRQKVLEGHLTAFSIGFESLRDEIKADEQGRPTRYIYEVKLYEVSIV  149

Query  143  GVPAYLGAQIAGVR  156
              PA   A I   +
Sbjct  150  PFPANENAVIMAAK  163


>gi|30263664|ref|NP_846041.1| prophage LambdaBa01, prohead protease, putative [Bacillus anthracis 
str. Ames]
 gi|47529073|ref|YP_020422.1| prophage lambdaba01, prohead protease [Bacillus anthracis str. 
'Ames Ancestor']
 gi|49186510|ref|YP_029762.1| prophage LambdaBa01, prohead protease [Bacillus anthracis str. 
Sterne]
 29 more sequence titles
 Length=194

 Score = 61.2 bits (147),  Expect = 5e-08, Method: Compositional matrix adjust.
 Identities = 54/165 (33%), Positives = 78/165 (48%), Gaps = 19/165 (11%)

Query  1    LSSILFRTAELRPGEG--RTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHK  58
            LSS L    E+R  E   RT+ G  V +   +        F+E F  GAF  S+ +    
Sbjct  10   LSSAL----EIRELENGLRTISGYAVKWEMKSVTMGYWQRFKEQFKKGAFTESLTQDDQL  65

Query  59   VKLLVSHDARTRYPVGRA----VELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFS  114
               L SHD  T   +GR     + L E+  GL    +LANT  G++    +K G VD  S
Sbjct  66   A--LWSHD--TSQVLGRTKNGTLRLFEDEIGLRFELDLANTTLGNDTYETIKRGDVDGVS  121

Query  115  VGFRPIR---DRREGDVIVR--VEAALLEVSLTGVPAYLGAQIAG  154
             GF+ ++   D  + D +VR   +A LLE+S    PAY  +Q++ 
Sbjct  122  FGFQMVKEEWDESDPDNVVRSVTKAKLLEISPVAFPAYPDSQVSA  166


>gi|167762229|ref|ZP_02434356.1| hypothetical protein BACSTE_00581 [Bacteroides stercoris ATCC 
43183]
 gi|167699872|gb|EDS16451.1| hypothetical protein BACSTE_00581 [Bacteroides stercoris ATCC 
43183]
Length=252

 Score = 61.2 bits (147),  Expect = 5e-08, Method: Compositional matrix adjust.
 Identities = 50/165 (31%), Positives = 75/165 (46%), Gaps = 27/165 (16%)

Query  1    LSSILFRTAELRPGEGRTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERG----  56
            L SI  +  +  P E RT+ G    +G V    D+          G F +SI ERG    
Sbjct  18   LFSINSKDVQYSP-ESRTISGYAAVFGNVDKAHDI-------LLKGCFSKSINERGPQSQ  69

Query  57   --HKVKLLVSHDARTRYPVGRAVELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFS  114
               K+ LL  HD     P+G   EL+E+  GL+    +     GD A+  +++G ++ FS
Sbjct  70   ANDKIILLWMHDMSE--PLGFITELKEDDRGLYFEARIDEIELGDRAIKQLESGTLNQFS  127

Query  115  VGFRPIRDRREGD-----VIVRVEAALLEVSL-----TGVPAYLG  149
            +G+  + +  E D     +IVR E  L E+S+      G   YLG
Sbjct  128  IGYEYVWENCEWDYEKQALIVR-EVKLYEISVVSIGCNGETEYLG  171


>gi|65320987|ref|ZP_00393946.1| COG3740: Phage head maturation protease [Bacillus anthracis str. 
A2012]
Length=196

 Score = 61.2 bits (147),  Expect = 5e-08, Method: Compositional matrix adjust.
 Identities = 54/165 (33%), Positives = 78/165 (48%), Gaps = 19/165 (11%)

Query  1    LSSILFRTAELRPGEG--RTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHK  58
            LSS L    E+R  E   RT+ G  V +   +        F+E F  GAF  S+ +    
Sbjct  12   LSSAL----EIRELENGLRTISGYAVKWEMKSVTMGYWQRFKEQFKKGAFTESLTQDDQL  67

Query  59   VKLLVSHDARTRYPVGRA----VELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFS  114
               L SHD  T   +GR     + L E+  GL    +LANT  G++    +K G VD  S
Sbjct  68   A--LWSHD--TSQVLGRTKNGTLRLFEDEIGLRFELDLANTTLGNDTYETIKRGDVDGVS  123

Query  115  VGFRPIR---DRREGDVIVR--VEAALLEVSLTGVPAYLGAQIAG  154
             GF+ ++   D  + D +VR   +A LLE+S    PAY  +Q++ 
Sbjct  124  FGFQMVKEEWDESDPDNVVRSVTKAKLLEISPVAFPAYPDSQVSA  168


>gi|163941346|ref|YP_001646230.1| HK97 family phage prohead protease [Bacillus weihenstephanensis 
KBAB4]
 gi|163863543|gb|ABY44602.1| phage prohead protease, HK97 family [Bacillus weihenstephanensis 
KBAB4]
Length=194

 Score = 61.2 bits (147),  Expect = 6e-08, Method: Compositional matrix adjust.
 Identities = 54/165 (33%), Positives = 78/165 (48%), Gaps = 19/165 (11%)

Query  1    LSSILFRTAELRPGEG--RTVYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHK  58
            LSS L    E+R  E   RT+ G  V +   +        F+E F  GAF  S+ +    
Sbjct  10   LSSAL----EIRELENGLRTISGYAVKWEMKSVTMGYWQRFKEQFKKGAFTDSLTQEDQL  65

Query  59   VKLLVSHDARTRYPVGRA----VELREEPHGLFGAFELANTPDGDEALANVKAGVVDAFS  114
               L SHD  T   +GR     + L E+  GL    +LANT  G++    +K G VD  S
Sbjct  66   A--LWSHD--TSQVLGRTKNGTLRLFEDEIGLRFELDLANTTLGNDTYETIKRGDVDGVS  121

Query  115  VGFRPIR---DRREGDVIVR--VEAALLEVSLTGVPAYLGAQIAG  154
             GF+ ++   D  + D +VR   +A LLE+S    PAY  +Q++ 
Sbjct  122  FGFQMVKEEWDESDPDNVVRSVTKAKLLEISPVAFPAYPDSQVSA  166


>gi|265983715|ref|ZP_06096450.1| protease [Brucella sp. 83/13]
 gi|306838716|ref|ZP_07471551.1| phage prohead protease, HK97 family [Brucella sp. NF 2653]
 gi|264662307|gb|EEZ32568.1| protease [Brucella sp. 83/13]
 gi|306406203|gb|EFM62447.1| phage prohead protease, HK97 family [Brucella sp. NF 2653]
Length=222

 Score = 61.2 bits (147),  Expect = 6e-08, Method: Compositional matrix adjust.
 Identities = 46/143 (33%), Positives = 73/143 (52%), Gaps = 9/143 (6%)

Query  19   VYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHK-VKLLVSHDARTRYPVGRAV  77
            + G    Y  V  + DL  +  E    GAF R++ ERG   V++L  HDA    P+G   
Sbjct  22   IDGSFSGYASVFGLPDLGNDVIEQ---GAFARALKERGASGVRMLWQHDAAE--PIGVWT  76

Query  78   ELREEPHGLFGAFELAN-TPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVR--VEA  134
            ++RE+  GL+    LA       EAL  +++G +D  S+GFR +R R++    +R   +A
Sbjct  77   QIREDARGLYVEGRLAKGVARAREALELMRSGGLDGLSIGFRTVRARKDARTGLRHITQA  136

Query  135  ALLEVSLTGVPAYLGAQIAGVRA  157
             L E+S+   P    A + G++A
Sbjct  137  DLWEISIVTFPMLPQAHVTGIKA  159


>gi|261213603|ref|ZP_05927884.1| phage prohead protease [Brucella abortus bv. 3 str. Tulya]
 gi|260915210|gb|EEX82071.1| phage prohead protease [Brucella abortus bv. 3 str. Tulya]
Length=222

 Score = 61.2 bits (147),  Expect = 6e-08, Method: Compositional matrix adjust.
 Identities = 46/143 (33%), Positives = 74/143 (52%), Gaps = 9/143 (6%)

Query  19   VYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHK-VKLLVSHDARTRYPVGRAV  77
            + G    Y  V  + DL  +  E    GAF R++ ERG   V++L  HDA    P+G   
Sbjct  22   IDGSFSGYASVFGLPDLGNDVIEQ---GAFARALKERGASGVRMLWQHDAAE--PIGVWT  76

Query  78   ELREEPHGLFGAFELAN-TPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVR--VEA  134
            ++RE+  GL+    LA       EAL  +++G +D  S+GFR +R R++    +R   +A
Sbjct  77   QIREDARGLYVEGRLAKGVARAREALELMRSGGLDGLSIGFRTVRARKDARTGLRHITQA  136

Query  135  ALLEVSLTGVPAYLGAQIAGVRA  157
             L E+S+   P    A++ G++A
Sbjct  137  NLWEISVVTFPMLPQARVTGIKA  159


>gi|294851958|ref|ZP_06792631.1| HK97 family phage prohead protease [Brucella sp. NVSL 07-0026]
 gi|294820547|gb|EFG37546.1| HK97 family phage prohead protease [Brucella sp. NVSL 07-0026]
Length=222

 Score = 60.8 bits (146),  Expect = 7e-08, Method: Compositional matrix adjust.
 Identities = 46/143 (33%), Positives = 74/143 (52%), Gaps = 9/143 (6%)

Query  19   VYGVIVPYGEVTTVRDLDGEFREMFAPGAFRRSIAERGHK-VKLLVSHDARTRYPVGRAV  77
            + G    Y  V  + DL  +  E    GAF R++ ERG   V++L  HDA    P+G   
Sbjct  22   IDGSFSGYASVFGLPDLGNDVIEQ---GAFARALKERGASGVRMLWQHDAAE--PIGVWT  76

Query  78   ELREEPHGLFGAFELAN-TPDGDEALANVKAGVVDAFSVGFRPIRDRREGDVIVR--VEA  134
            ++RE+  GL+    LA       EAL  +++G +D  S+GFR +R R++    +R   +A
Sbjct  77   QIREDARGLYVEGRLAKGVARAREALELMRSGGLDGLSIGFRTVRARKDARTGLRHITQA  136

Query  135  ALLEVSLTGVPAYLGAQIAGVRA  157
             L E+S+   P    A++ G++A
Sbjct  137  DLWEISVVTFPMLPQARVTGIKA  159



Lambda     K      H
   0.321    0.139    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 152280848256


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40