BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2671 Length=258 Score E Sequences producing significant alignments: (Bits) Value gi|15609808|ref|NP_217187.1| hypothetical protein Rv2671 [Mycoba... 509 1e-142 gi|15842209|ref|NP_337246.1| hypothetical protein MT2745 [Mycoba... 472 2e-131 gi|15827698|ref|NP_301961.1| hypothetical protein ML1340 [Mycoba... 369 3e-100 gi|183982058|ref|YP_001850349.1| bifunctional enzyme riboflavin ... 356 2e-96 gi|118618636|ref|YP_906968.1| hypothetical protein MUL_3305 [Myc... 350 1e-94 gi|41408889|ref|NP_961725.1| hypothetical protein MAP2791 [Mycob... 348 4e-94 gi|118463485|ref|YP_882741.1| hypothetical protein MAV_3563 [Myc... 348 6e-94 gi|342858458|ref|ZP_08715113.1| hypothetical protein MCOL_06271 ... 345 5e-93 gi|254776005|ref|ZP_05217521.1| hypothetical protein MaviaA2_152... 342 3e-92 gi|240169734|ref|ZP_04748393.1| hypothetical protein MkanA1_1050... 335 3e-90 gi|254818548|ref|ZP_05223549.1| hypothetical protein MintA_01421... 317 8e-85 gi|296171942|ref|ZP_06852987.1| 5-amino-6-(5-phosphoribosylamino... 317 1e-84 gi|333991057|ref|YP_004523671.1| bifunctional enzyme riboflavin ... 308 6e-82 gi|108799186|ref|YP_639383.1| hypothetical protein Mmcs_2219 [My... 242 5e-62 gi|145224494|ref|YP_001135172.1| hypothetical protein Mflv_3913 ... 238 6e-61 gi|120403479|ref|YP_953308.1| hypothetical protein Mvan_2490 [My... 230 1e-58 gi|118472351|ref|YP_887118.1| hypothetical protein MSMEG_2787 [M... 226 2e-57 gi|169630059|ref|YP_001703708.1| hypothetical protein MAB_2976 [... 200 1e-49 gi|111023823|ref|YP_706795.1| hypothetical protein RHA1_ro06865 ... 195 5e-48 gi|226366259|ref|YP_002784042.1| hypothetical protein ROP_68500 ... 188 8e-46 gi|312139475|ref|YP_004006811.1| 5-amino-6-(5-phosphoribosylamin... 188 8e-46 gi|269126013|ref|YP_003299383.1| bifunctional deaminase-reductas... 171 1e-40 gi|333919455|ref|YP_004493036.1| riboflavin biosynthesis protein... 169 3e-40 gi|134098447|ref|YP_001104108.1| 5-amino-6-(5-phosphoribosylamin... 167 1e-39 gi|291003336|ref|ZP_06561309.1| 5-amino-6-(5-phosphoribosylamino... 167 1e-39 gi|226306344|ref|YP_002766304.1| hypothetical protein RER_28570 ... 166 4e-39 gi|229491248|ref|ZP_04385074.1| riboflavin biosynthesis protein ... 165 6e-39 gi|88856373|ref|ZP_01131032.1| hypothetical protein A20C1_00495 ... 164 1e-38 gi|54025702|ref|YP_119944.1| hypothetical protein nfa37320 [Noca... 163 2e-38 gi|50955356|ref|YP_062644.1| hypothetical protein Lxx17960 [Leif... 160 2e-37 gi|291301495|ref|YP_003512773.1| bifunctional deaminase-reductas... 159 4e-37 gi|284033054|ref|YP_003382985.1| bifunctional deaminase-reductas... 159 4e-37 gi|257056391|ref|YP_003134223.1| pyrimidine reductase, riboflavi... 157 1e-36 gi|329940196|ref|ZP_08289478.1| 5-amino-6-(5-phosphoribosylamino... 157 1e-36 gi|111221547|ref|YP_712341.1| hypothetical protein FRAAL2113 [Fr... 153 2e-35 gi|326444043|ref|ZP_08218777.1| hypothetical protein SclaA2_2339... 152 4e-35 gi|294815697|ref|ZP_06774340.1| Bifunctional deaminase-reductase... 152 4e-35 gi|331696725|ref|YP_004332964.1| bifunctional deaminase-reductas... 152 6e-35 gi|254387285|ref|ZP_05002544.1| 5-amino-6-(5-phosphoribosylamino... 151 7e-35 gi|315502712|ref|YP_004081599.1| bifunctional deaminase-reductas... 151 1e-34 gi|311898892|dbj|BAJ31300.1| hypothetical protein KSE_55250 [Kit... 150 1e-34 gi|320007797|gb|ADW02647.1| bifunctional deaminase-reductase dom... 150 1e-34 gi|345009984|ref|YP_004812338.1| bifunctional deaminase-reductas... 150 2e-34 gi|258653701|ref|YP_003202857.1| bifunctional deaminase-reductas... 149 3e-34 gi|297156476|gb|ADI06188.1| hypothetical protein SBI_03067 [Stre... 149 3e-34 gi|271967965|ref|YP_003342161.1| pyrimidine reductase riboflavin... 149 3e-34 gi|254393143|ref|ZP_05008301.1| diaminohydroxyphosphoribosylamin... 149 5e-34 gi|291454887|ref|ZP_06594277.1| 5-amino-6-(5-phosphoribosylamino... 149 5e-34 gi|117928582|ref|YP_873133.1| deaminase-reductase domain-contain... 148 7e-34 gi|328885914|emb|CCA59153.1| 5-amino-6-(5-phosphoribosylamino)ur... 148 7e-34 >gi|15609808|ref|NP_217187.1| hypothetical protein Rv2671 [Mycobacterium tuberculosis H37Rv] gi|31793843|ref|NP_856336.1| hypothetical protein Mb2690 [Mycobacterium bovis AF2122/97] gi|121638546|ref|YP_978770.1| hypothetical protein BCG_2684 [Mycobacterium bovis BCG str. Pasteur 1173P2] 78 more sequence titles Length=258 Score = 509 bits (1312), Expect = 1e-142, Method: Compositional matrix adjust. Identities = 258/258 (100%), Positives = 258/258 (100%), Gaps = 0/258 (0%) Query 1 MPDSGQLGAADTPLRLLSSVHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSG 60 MPDSGQLGAADTPLRLLSSVHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSG Sbjct 1 MPDSGQLGAADTPLRLLSSVHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSG 60 Query 61 AMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIV 120 AMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIV Sbjct 61 AMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIV 120 Query 121 TRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVS 180 TRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVS Sbjct 121 TRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVS 180 Query 181 QLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRC 240 QLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRC Sbjct 181 QLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRC 240 Query 241 AHVLTDDSGYLYTRYVKT 258 AHVLTDDSGYLYTRYVKT Sbjct 241 AHVLTDDSGYLYTRYVKT 258 >gi|15842209|ref|NP_337246.1| hypothetical protein MT2745 [Mycobacterium tuberculosis CDC1551] gi|13882497|gb|AAK47060.1| riboflavin-specific deaminase-related protein [Mycobacterium tuberculosis CDC1551] Length=239 Score = 472 bits (1215), Expect = 2e-131, Method: Compositional matrix adjust. Identities = 238/239 (99%), Positives = 239/239 (100%), Gaps = 0/239 (0%) Query 20 VHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELAD 79 +HYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELAD Sbjct 1 MHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELAD 60 Query 80 VIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMA 139 VIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMA Sbjct 61 VIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMA 120 Query 140 PLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLL 199 PLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLL Sbjct 121 PLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLL 180 Query 200 GTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVKT 258 GTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVKT Sbjct 181 GTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVKT 239 >gi|15827698|ref|NP_301961.1| hypothetical protein ML1340 [Mycobacterium leprae TN] gi|221230175|ref|YP_002503591.1| hypothetical protein MLBr_01340 [Mycobacterium leprae Br4923] gi|2065234|emb|CAB08270.1| hypothetical protein MLC1351.23 [Mycobacterium leprae] gi|13093249|emb|CAC31721.1| possible reductase [Mycobacterium leprae] gi|219933282|emb|CAR71435.1| possible reductase [Mycobacterium leprae Br4923] Length=268 Score = 369 bits (946), Expect = 3e-100, Method: Compositional matrix adjust. Identities = 183/251 (73%), Positives = 207/251 (83%), Gaps = 2/251 (0%) Query 9 AADTPLRLLSSVHYLTDGELPQLYDYPDD--GTWLRANFISSLDGGATVDGTSGAMAGPG 66 AA TPL +L+S YL D EL QLY YP + G W+RANFI+S+DGGAT DG +GAMAGPG Sbjct 17 AAQTPLLMLTSGRYLDDDELSQLYGYPSERAGVWIRANFITSIDGGATADGRTGAMAGPG 76 Query 67 DRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRL 126 DRFVFN+LRELADVIVVG GTVRIE YSG + V +RQ RQARGQSEVPQLAIVT SGRL Sbjct 77 DRFVFNMLRELADVIVVGAGTVRIENYSGAHLPVTKRQQRQARGQSEVPQLAIVTNSGRL 136 Query 127 DRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARG 186 DRDMAVFTRTE+APLVLT T A R RLA LA V++CSGDDP VDE V+++ L RG Sbjct 137 DRDMAVFTRTEIAPLVLTCTETAKKLRTRLADLAYVVSCSGDDPSKVDETVVLATLQTRG 196 Query 187 LRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTD 246 LRR+LTEGGP LLG+F++ +LDELCLTIAP +VGG ARRI TGP Q+LTRMRCAHVLTD Sbjct 197 LRRVLTEGGPMLLGSFIQHGMLDELCLTIAPLIVGGRARRIATGPEQLLTRMRCAHVLTD 256 Query 247 DSGYLYTRYVK 257 D+GYLYTRYVK Sbjct 257 DAGYLYTRYVK 267 >gi|183982058|ref|YP_001850349.1| bifunctional enzyme riboflavin biosynthesis protein RibD [Mycobacterium marinum M] gi|183175384|gb|ACC40494.1| bifunctional enzyme riboflavin biosynthesis protein RibD [Mycobacterium marinum M] Length=260 Score = 356 bits (913), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 180/259 (70%), Positives = 209/259 (81%), Gaps = 2/259 (0%) Query 1 MPDSGQLGAADTPLRLLSSVHYLTDGELPQLYDYPDD--GTWLRANFISSLDGGATVDGT 58 MPD +AD L LL + LTD +LP+ Y YP GTWLRANFI+SLDGGATV GT Sbjct 1 MPDPTSGRSADAQLTLLGTDRQLTDEDLPEFYGYPAKLSGTWLRANFITSLDGGATVGGT 60 Query 59 SGAMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLA 118 SG +AGPGDR VF LLRELADVI+VG GTVRIEGYSG ++GV +RQ RQARGQSEVPQLA Sbjct 61 SGGLAGPGDRAVFVLLRELADVILVGAGTVRIEGYSGAQLGVAERQQRQARGQSEVPQLA 120 Query 119 IVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVL 178 I T SG+LDRD+ VFTRTE+ PLVLT A DTR+RL GLAEV+ CSG DP VDE +L Sbjct 121 IATNSGQLDRDLPVFTRTEVPPLVLTAAAAVYDTRRRLTGLAEVVDCSGKDPHRVDEGLL 180 Query 179 VSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRM 238 +++LA RG+RRILTEGGPTL G+ +E+D+LDELCLTIAP VVGGL RRI +GPGQ+ TRM Sbjct 181 LARLAGRGMRRILTEGGPTLFGSLIEQDLLDELCLTIAPVVVGGLPRRIASGPGQLQTRM 240 Query 239 RCAHVLTDDSGYLYTRYVK 257 CAHV+TDD+GYLYTRYV+ Sbjct 241 HCAHVITDDAGYLYTRYVR 259 >gi|118618636|ref|YP_906968.1| hypothetical protein MUL_3305 [Mycobacterium ulcerans Agy99] gi|118570746|gb|ABL05497.1| bifunctional enzyme riboflavin biosynthesis protein RibD [Mycobacterium ulcerans Agy99] Length=260 Score = 350 bits (898), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 178/259 (69%), Positives = 206/259 (80%), Gaps = 2/259 (0%) Query 1 MPDSGQLGAADTPLRLLSSVHYLTDGELPQLYDYPDD--GTWLRANFISSLDGGATVDGT 58 MPD +AD L LL + LTD +LP+ Y YP TWLRANFI+SLDGGATV GT Sbjct 1 MPDPTSGRSADAQLTLLGTDRQLTDEDLPEFYGYPAKLSSTWLRANFITSLDGGATVGGT 60 Query 59 SGAMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLA 118 SG +AGPGDR VF LLRELADVI+VG GTVRIEGYSG + GV +RQ RQARGQSEVPQLA Sbjct 61 SGGLAGPGDRAVFVLLRELADVILVGAGTVRIEGYSGAQRGVAERQQRQARGQSEVPQLA 120 Query 119 IVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVL 178 I T SG+LDRD+ VFTRTE+ PLVLT A DTR+RL GLAEV+ CSG DP VDE +L Sbjct 121 IATNSGQLDRDLPVFTRTEVPPLVLTAAAAVYDTRRRLTGLAEVVGCSGKDPHRVDEGLL 180 Query 179 VSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRM 238 +++LA RG+R ILTEGGPTL G+ +E+D+LDELCLTIAP VVGGL RRI +GPGQ+ TRM Sbjct 181 LARLAGRGMRCILTEGGPTLFGSLIEQDLLDELCLTIAPVVVGGLPRRIASGPGQLQTRM 240 Query 239 RCAHVLTDDSGYLYTRYVK 257 CAHV+TDD+GYLYTRYV+ Sbjct 241 HCAHVITDDAGYLYTRYVR 259 >gi|41408889|ref|NP_961725.1| hypothetical protein MAP2791 [Mycobacterium avium subsp. paratuberculosis K-10] gi|41397248|gb|AAS05108.1| RibD [Mycobacterium avium subsp. paratuberculosis K-10] gi|336458830|gb|EGO37787.1| pyrimidine reductase, riboflavin biosynthesis [Mycobacterium avium subsp. paratuberculosis S397] Length=254 Score = 348 bits (894), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 185/249 (75%), Positives = 210/249 (85%), Gaps = 2/249 (0%) Query 11 DTPLRLLSSVHYLTDGELPQLYDYPDD--GTWLRANFISSLDGGATVDGTSGAMAGPGDR 68 +TPL LL SV + DGELP LYDYPD GTW+RANFI+S+DGGAT DG+SGAM GPGDR Sbjct 5 ETPLSLLGSVREVDDGELPGLYDYPDGHAGTWVRANFIASVDGGATADGSSGAMGGPGDR 64 Query 69 FVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDR 128 FVFNLLRELADVIVVG GTVRIEGYSG ++GV QRQ RQARGQSEVP L IVT+SG L+R Sbjct 65 FVFNLLRELADVIVVGAGTVRIEGYSGAQLGVAQRQQRQARGQSEVPPLGIVTKSGHLNR 124 Query 129 DMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLR 188 DMAVFTRTE+ PLVLT A AD TR+ L+GL EV+ CS DP VDEA +++ L RG+R Sbjct 125 DMAVFTRTEVPPLVLTCAAAADQTRRLLSGLCEVLDCSAGDPERVDEATMLALLGKRGMR 184 Query 189 RILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDS 248 RILTEGGPTLL + +ER +LDELCLTIAPY+VGG ARRI TGPGQ+LTRMRCAHVLTDD+ Sbjct 185 RILTEGGPTLLNSLLERQLLDELCLTIAPYLVGGHARRIATGPGQLLTRMRCAHVLTDDA 244 Query 249 GYLYTRYVK 257 GYLYTRYV+ Sbjct 245 GYLYTRYVR 253 >gi|118463485|ref|YP_882741.1| hypothetical protein MAV_3563 [Mycobacterium avium 104] gi|118164772|gb|ABK65669.1| riboflavin biosynthesis protein RibD C- domain protein [Mycobacterium avium 104] Length=254 Score = 348 bits (892), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 185/249 (75%), Positives = 210/249 (85%), Gaps = 2/249 (0%) Query 11 DTPLRLLSSVHYLTDGELPQLYDYPD--DGTWLRANFISSLDGGATVDGTSGAMAGPGDR 68 +TPL LL SV + DGELP LYDYPD GTW+RANFI+S+DGGAT DG+SGAM GPGDR Sbjct 5 ETPLSLLGSVREVDDGELPGLYDYPDRHAGTWVRANFIASVDGGATADGSSGAMGGPGDR 64 Query 69 FVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDR 128 FVFNLLRELADVIVVG GTVRIEGYSG ++GV QRQ RQARGQSEVP L IVT+SG L+R Sbjct 65 FVFNLLRELADVIVVGAGTVRIEGYSGAQLGVAQRQQRQARGQSEVPPLGIVTKSGHLNR 124 Query 129 DMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLR 188 DMAVFTRTE+ PLVLT A AD TR+ L+GL EV+ CS DP VDEA +++ L RG+R Sbjct 125 DMAVFTRTEVPPLVLTCAAAADQTRRLLSGLCEVLDCSAGDPERVDEATMLALLGERGMR 184 Query 189 RILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDS 248 RILTEGGPTLL + +ER +LDELCLTIAPY+VGG ARRI TGPGQ+LTRMRCAHVLTDD+ Sbjct 185 RILTEGGPTLLNSLLERQLLDELCLTIAPYLVGGHARRIATGPGQLLTRMRCAHVLTDDA 244 Query 249 GYLYTRYVK 257 GYLYTRYV+ Sbjct 245 GYLYTRYVR 253 >gi|342858458|ref|ZP_08715113.1| hypothetical protein MCOL_06271 [Mycobacterium colombiense CECT 3035] gi|342134162|gb|EGT87342.1| hypothetical protein MCOL_06271 [Mycobacterium colombiense CECT 3035] Length=265 Score = 345 bits (884), Expect = 5e-93, Method: Compositional matrix adjust. Identities = 190/264 (72%), Positives = 219/264 (83%), Gaps = 7/264 (2%) Query 1 MPDSG------QLGAADTPLRLLSSVHYLTDGELPQLYDYPD-DGTWLRANFISSLDGGA 53 MPDSG ++TPL LL +V L DG+LP+LYDYP+ DGTW+RANFI+S+DGGA Sbjct 1 MPDSGGPESFATSATSETPLSLLGAVRGLDDGDLPRLYDYPEHDGTWVRANFITSVDGGA 60 Query 54 TVDGTSGAMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSE 113 T G+SGAM GPGDRF+FNLLRELADVIVVG GTVRIEGYSG ++G +RQ RQARGQSE Sbjct 61 TTGGSSGAMGGPGDRFIFNLLRELADVIVVGAGTVRIEGYSGAQVGAAERQRRQARGQSE 120 Query 114 VPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTV 173 VPQLAIVT SG L+RDMAVFTRTE+ PLVLT TA A+ TR+ L+GL EV+ CSG DP V Sbjct 121 VPQLAIVTGSGHLNRDMAVFTRTEVQPLVLTCTAAAEQTRRALSGLCEVLDCSGRDPEKV 180 Query 174 DEAVLVSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQ 233 DEA L++ LAARG+R ILTEGGPTLL + + RD+LDELCLTIAP +VGG ARRI TGPGQ Sbjct 181 DEAALLAALAARGMRHILTEGGPTLLDSLMRRDMLDELCLTIAPCLVGGQARRIATGPGQ 240 Query 234 VLTRMRCAHVLTDDSGYLYTRYVK 257 +LTRMRCAHVLTDD+GYLYTRYVK Sbjct 241 LLTRMRCAHVLTDDAGYLYTRYVK 264 >gi|254776005|ref|ZP_05217521.1| hypothetical protein MaviaA2_15235 [Mycobacterium avium subsp. avium ATCC 25291] Length=254 Score = 342 bits (877), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 183/249 (74%), Positives = 208/249 (84%), Gaps = 2/249 (0%) Query 11 DTPLRLLSSVHYLTDGELPQLYDYPDD--GTWLRANFISSLDGGATVDGTSGAMAGPGDR 68 +TPL LL SV + DGELP LYDYPD GTW+RANFI+S+DGGAT DG+SGAM GPGDR Sbjct 5 ETPLSLLGSVREVDDGELPGLYDYPDGHAGTWVRANFIASVDGGATADGSSGAMGGPGDR 64 Query 69 FVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDR 128 VFNLLRELADVIVVG GTVRIEGYSG ++GV QRQ RQARGQSEVP IVT+SG L+R Sbjct 65 SVFNLLRELADVIVVGAGTVRIEGYSGAQLGVAQRQQRQARGQSEVPPPGIVTKSGHLNR 124 Query 129 DMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLR 188 DMAVFTRTE+ PLVLT A AD TR+ L+GL EV+ CS DP VDEA +++ L RG+R Sbjct 125 DMAVFTRTEVPPLVLTCAAAADQTRRLLSGLCEVLDCSAGDPERVDEATMLALLGERGMR 184 Query 189 RILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDS 248 RILTEGGPTLL + +ER +LDELCLTIAPY+VGG ARRI TGPGQ+LTRMRCAHVLTDD+ Sbjct 185 RILTEGGPTLLNSLLERQLLDELCLTIAPYLVGGHARRIATGPGQLLTRMRCAHVLTDDA 244 Query 249 GYLYTRYVK 257 GYLYTRYV+ Sbjct 245 GYLYTRYVR 253 >gi|240169734|ref|ZP_04748393.1| hypothetical protein MkanA1_10502 [Mycobacterium kansasii ATCC 12478] Length=264 Score = 335 bits (860), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 187/263 (72%), Positives = 211/263 (81%), Gaps = 6/263 (2%) Query 1 MPDSGQLGAADTP----LRLLSSVHYLTDGELPQLYDYPDD--GTWLRANFISSLDGGAT 54 MPD G AA L LL S L + +LP+ Y YP D G WLRANFISS+DGGAT Sbjct 1 MPDFGAGPAAGRSAGIRLTLLGSDRTLDEADLPEYYRYPPDVNGIWLRANFISSVDGGAT 60 Query 55 VDGTSGAMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEV 114 V GTSG + GPGDR VF LLRELADVIVVG GTVR+EGYSG ++ V R+ RQ RGQSEV Sbjct 61 VAGTSGGLGGPGDRAVFRLLRELADVIVVGAGTVRVEGYSGAQLSVAARRQRQLRGQSEV 120 Query 115 PQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVD 174 PQLAIVT+SG L RD+AVFTRTE+ PLVLT TAVAD+TR+ L GLAEV+ CS DP VD Sbjct 121 PQLAIVTKSGHLARDLAVFTRTEVPPLVLTATAVADETRRGLTGLAEVVDCSDTDPVKVD 180 Query 175 EAVLVSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQV 234 EAVL+++LA RGLRRILTEGGP LLG+F+ER +LDELCLTIAP+VVGGLARRIVTGPGQ+ Sbjct 181 EAVLLARLAERGLRRILTEGGPILLGSFIERGLLDELCLTIAPFVVGGLARRIVTGPGQL 240 Query 235 LTRMRCAHVLTDDSGYLYTRYVK 257 T MRCAHVLTDD+GYLYTRYVK Sbjct 241 KTPMRCAHVLTDDAGYLYTRYVK 263 >gi|254818548|ref|ZP_05223549.1| hypothetical protein MintA_01421 [Mycobacterium intracellulare ATCC 13950] Length=251 Score = 317 bits (813), Expect = 8e-85, Method: Compositional matrix adjust. Identities = 182/248 (74%), Positives = 209/248 (85%), Gaps = 1/248 (0%) Query 11 DTPLRLLSSVHYLTDGELPQLYDYPD-DGTWLRANFISSLDGGATVDGTSGAMAGPGDRF 69 +TPL LL SV L DGELP+LY YP+ D TW+RANFI+S+DGGAT G+SGAM GPGDRF Sbjct 3 ETPLSLLGSVRDLEDGELPRLYGYPEHDATWVRANFITSVDGGATSGGSSGAMGGPGDRF 62 Query 70 VFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRD 129 +FNLLRELADVIVVG GTVRIEGYSG ++G QRQHRQARGQSEVP LAIVT+SG L+RD Sbjct 63 IFNLLRELADVIVVGAGTVRIEGYSGAQLGAAQRQHRQARGQSEVPPLAIVTKSGHLNRD 122 Query 130 MAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRR 189 MAVFTRTE+ PLVLT A A TR+ L+G+ EV+ CS DP VDEA L++ L ARGLRR Sbjct 123 MAVFTRTEVPPLVLTCAAAAAQTRRLLSGVCEVLDCSAGDPEKVDEAALLAALGARGLRR 182 Query 190 ILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSG 249 ILTEGGP LLG+ ++RD+LDELCLTIAPY+VGG ARRI GPGQ+LT MRCAHVLTDD+G Sbjct 183 ILTEGGPMLLGSLIDRDMLDELCLTIAPYIVGGQARRIAAGPGQLLTGMRCAHVLTDDAG 242 Query 250 YLYTRYVK 257 YLYTRYV+ Sbjct 243 YLYTRYVR 250 >gi|296171942|ref|ZP_06852987.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295893875|gb|EFG73647.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=253 Score = 317 bits (811), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 183/248 (74%), Positives = 208/248 (84%), Gaps = 1/248 (0%) Query 11 DTPLRLLSSVHYLTDGELPQLYDYPD-DGTWLRANFISSLDGGATVDGTSGAMAGPGDRF 69 +TPL LL SV L DG LP+LY YP+ DGTW+RANFI+S+DGGAT G+SG M GPGDRF Sbjct 5 ETPLSLLGSVGELDDGALPRLYAYPERDGTWVRANFIASVDGGATSGGSSGTMGGPGDRF 64 Query 70 VFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRD 129 VFNLLRELADVIVVG GTVR+EGYSG ++ V QRQ RQ RGQSEVP LAIVT+SGRLDRD Sbjct 65 VFNLLRELADVIVVGAGTVRVEGYSGAQLSVAQRQQRQDRGQSEVPPLAIVTKSGRLDRD 124 Query 130 MAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRR 189 MAVFTRTE+ PLVLT A AD R+ L + EV+ CSGDDPG VDEAVL++ L ARG+RR Sbjct 125 MAVFTRTEVPPLVLTCAAAADPARRLLGEVCEVVDCSGDDPGAVDEAVLLATLGARGMRR 184 Query 190 ILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSG 249 ILTEGGP LL + + RD+LDELCLT+APY+VGGLARRI TGP Q+LTRMR AHVLTDD+G Sbjct 185 ILTEGGPMLLDSLIRRDMLDELCLTVAPYLVGGLARRIATGPSQLLTRMRRAHVLTDDAG 244 Query 250 YLYTRYVK 257 YLYTRYVK Sbjct 245 YLYTRYVK 252 >gi|333991057|ref|YP_004523671.1| bifunctional enzyme riboflavin biosynthesis protein RibD [Mycobacterium sp. JDM601] gi|333487025|gb|AEF36417.1| bifunctional enzyme riboflavin biosynthesis protein RibD [Mycobacterium sp. JDM601] Length=261 Score = 308 bits (789), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 157/246 (64%), Positives = 190/246 (78%), Gaps = 4/246 (1%) Query 17 LSSVHYLTDGELPQLYDYP--DDG--TWLRANFISSLDGGATVDGTSGAMAGPGDRFVFN 72 L S + D EL +LY YP DDG +WLRANFI S+DGGAT+ G SG + PGDR +F Sbjct 13 LDSTEPVDDAELARLYAYPESDDGPRSWLRANFIGSIDGGATMAGKSGGLGSPGDRALFM 72 Query 73 LLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAV 132 LLR LADV++VG GTVR+E Y G R+ V +R R+ RGQSEVP LAIV+RSG+LDRD V Sbjct 73 LLRALADVVLVGAGTVRVENYGGARLNVTERLRRRDRGQSEVPGLAIVSRSGQLDRDARV 132 Query 133 FTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILT 192 FT TE+ PLVLT+ + A+ TR+RL G AEV+ CS D VDEA +++ LA RG R+LT Sbjct 133 FTDTELPPLVLTSASAAEATRRRLDGRAEVLNCSAGDRDRVDEAAVLAALAGRGHHRVLT 192 Query 193 EGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLY 252 EGGPTLLG+FVERD+LDELCLT+APY+VGGLARRI TGPG+V T MRCAH+L D+SGYLY Sbjct 193 EGGPTLLGSFVERDLLDELCLTVAPYLVGGLARRIATGPGEVATPMRCAHLLVDESGYLY 252 Query 253 TRYVKT 258 RYVK+ Sbjct 253 GRYVKS 258 >gi|108799186|ref|YP_639383.1| hypothetical protein Mmcs_2219 [Mycobacterium sp. MCS] gi|119868301|ref|YP_938253.1| hypothetical protein Mkms_2265 [Mycobacterium sp. KMS] gi|126434794|ref|YP_001070485.1| hypothetical protein Mjls_2208 [Mycobacterium sp. JLS] gi|108769605|gb|ABG08327.1| bifunctional deaminase-reductase-like protein [Mycobacterium sp. MCS] gi|119694390|gb|ABL91463.1| bifunctional deaminase-reductase domain protein [Mycobacterium sp. KMS] gi|126234594|gb|ABN97994.1| bifunctional deaminase-reductase domain protein [Mycobacterium sp. JLS] Length=257 Score = 242 bits (617), Expect = 5e-62, Method: Compositional matrix adjust. Identities = 136/259 (53%), Positives = 173/259 (67%), Gaps = 6/259 (2%) Query 1 MPDSGQLGAADTPLRLLSSVHYLTDGELPQLYDYPDD--GTWLRANFISSLDGGATVDGT 58 MPDS AA T +L +V + D + Y YPD W+R N I+S+DGGATV G Sbjct 1 MPDS----AAGTQFTVLGAVESVADDRVGDFYAYPDALRRCWVRGNMIASVDGGATVAGR 56 Query 59 SGAMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLA 118 SG + GDR +F +R+ ADVIVVG TVR E YSG ++ RQ R ARGQSEVP +A Sbjct 57 SGGLGAAGDRALFAKMRQAADVIVVGASTVRTEDYSGAQLSAAARQDRAARGQSEVPPIA 116 Query 119 IVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVL 178 ++TRS LD D +F RTE+ P++LT+ A R+R GLA+V+ SG +P VD A Sbjct 117 VLTRSADLDHDAKLFRRTEVPPILLTSARTAATARERFGGLADVVDASGPEPDDVDPATA 176 Query 179 VSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRM 238 + LAARGL R+LTEGGP +LG F D+LDELC+T+AP +VGG A+RIVTGPGQV T + Sbjct 177 LDLLAARGLLRVLTEGGPGVLGLFTAADLLDELCVTVAPVLVGGEAQRIVTGPGQVRTPL 236 Query 239 RCAHVLTDDSGYLYTRYVK 257 R +H+L DD GYLY RYV+ Sbjct 237 RRSHILGDDDGYLYCRYVR 255 >gi|145224494|ref|YP_001135172.1| hypothetical protein Mflv_3913 [Mycobacterium gilvum PYR-GCK] gi|315444825|ref|YP_004077704.1| pyrimidine reductase, riboflavin biosynthesis [Mycobacterium sp. Spyr1] gi|145216980|gb|ABP46384.1| bifunctional deaminase-reductase domain protein [Mycobacterium gilvum PYR-GCK] gi|315263128|gb|ADT99869.1| pyrimidine reductase, riboflavin biosynthesis [Mycobacterium sp. Spyr1] Length=257 Score = 238 bits (607), Expect = 6e-61, Method: Compositional matrix adjust. Identities = 132/233 (57%), Positives = 167/233 (72%), Gaps = 2/233 (0%) Query 27 ELPQLYDYPD--DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVG 84 +L Y YPD D W+RAN I+S+DGGAT G SG + G GDR +F+ LRELADVIVVG Sbjct 23 DLAAHYPYPDGLDSCWVRANMITSVDGGATSAGKSGGLGGDGDRALFSALRELADVIVVG 82 Query 85 VGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLT 144 TVR E YSGVR+ R RQ RGQSEVP +A++TRSGRLDRD +FTRT++ PL+LT Sbjct 83 AQTVRSEDYSGVRLSASARLARQQRGQSEVPPIAVLTRSGRLDRDAKLFTRTDVPPLILT 142 Query 145 TTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVE 204 +T DDTR+ L +AEV+ SG P +VD A ++ LA RGLRR+LTEGGP +LG F + Sbjct 143 STRALDDTRRLLGSVAEVLDASGAQPDSVDPAQALTLLAERGLRRVLTEGGPGILGMFTD 202 Query 205 RDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 D++DELC+T+AP ++GG RIVTG G+V + M H LTD GYLY RY++ Sbjct 203 DDLVDELCVTVAPLLLGGGPGRIVTGDGEVRSGMVLGHALTDGDGYLYLRYLR 255 >gi|120403479|ref|YP_953308.1| hypothetical protein Mvan_2490 [Mycobacterium vanbaalenii PYR-1] gi|119956297|gb|ABM13302.1| bifunctional deaminase-reductase domain protein [Mycobacterium vanbaalenii PYR-1] Length=264 Score = 230 bits (587), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 130/248 (53%), Positives = 170/248 (69%), Gaps = 2/248 (0%) Query 12 TPLRLLSSVHYLTDGELPQLYDYPD--DGTWLRANFISSLDGGATVDGTSGAMAGPGDRF 69 T LL + L + Y YPD W+RAN I+S+DGGAT G SG + G GDR Sbjct 8 TQFTLLGRIEELGAEGVAAHYGYPDGLQSCWVRANMIASVDGGATSGGKSGGLGGDGDRA 67 Query 70 VFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRD 129 +F LR+LADVIVVG TVR+E YSGV++G +R RQ RGQ+EVP +A++TRSG LDRD Sbjct 68 LFATLRDLADVIVVGAATVRVENYSGVQLGAAERLARQRRGQAEVPPVAVLTRSGLLDRD 127 Query 130 MAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRR 189 +F T++ PL+LT++ +DTRQRL +AEV+ SG P +VD + LA RGL R Sbjct 128 AKLFHLTDVPPLILTSSDAVEDTRQRLGAVAEVVDASGPAPDSVDLRTALDLLAERGLVR 187 Query 190 ILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSG 249 +LTEGGP +LG F E+D+LDELCLT+AP ++GG + RIVTG G+V + + H LTDD G Sbjct 188 VLTEGGPGILGMFTEQDLLDELCLTVAPLLLGGGSARIVTGLGEVRSDLALLHALTDDRG 247 Query 250 YLYTRYVK 257 +LY RYV+ Sbjct 248 FLYLRYVR 255 >gi|118472351|ref|YP_887118.1| hypothetical protein MSMEG_2787 [Mycobacterium smegmatis str. MC2 155] gi|118173638|gb|ABK74534.1| putative riboflavin biosynthesis protein RibD [Mycobacterium smegmatis str. MC2 155] Length=260 Score = 226 bits (576), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 141/236 (60%), Positives = 167/236 (71%), Gaps = 3/236 (1%) Query 25 DGELP-QLYDYPDD--GTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVI 81 D EL + Y YPDD +RAN I SLDG AT DG SG + G GDR VFNL+RE ADVI Sbjct 24 DDELTTRFYAYPDDLRKCRVRANMIVSLDGAATQDGKSGGLGGAGDRAVFNLMRETADVI 83 Query 82 VVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPL 141 ++G TVRIE YSGV++ V QRQ RQ RGQ+EVP +AIVT S L+ D +FTRTE+ PL Sbjct 84 LMGASTVRIENYSGVQLSVPQRQARQRRGQAEVPPIAIVTASADLEPDAKIFTRTEVRPL 143 Query 142 VLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGT 201 +LTT D R+RL G+AEV+ SG D VD A + LA R L R+LTEGGP+LLG Sbjct 144 ILTTAHTVSDARRRLGGVAEVLDASGADRTRVDPARALQILAERKLFRVLTEGGPSLLGL 203 Query 202 FVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 +E D+LDELCLTIAP +VGG A RI G GQ TRMR +H+LTDD GYLYTRYV+ Sbjct 204 LIEHDLLDELCLTIAPVLVGGGAPRIAAGIGQARTRMRVSHLLTDDEGYLYTRYVR 259 >gi|169630059|ref|YP_001703708.1| hypothetical protein MAB_2976 [Mycobacterium abscessus ATCC 19977] gi|169242026|emb|CAM63054.1| Conserved hypothetical protein (possible reductase) [Mycobacterium abscessus] Length=260 Score = 200 bits (509), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 123/250 (50%), Positives = 159/250 (64%), Gaps = 4/250 (1%) Query 8 GAADTPLRLLSSVHYLTDGELPQLYDYP-DDGTWLRANFISSLDGGATVDGTSGAMAGPG 66 G A T L L++ + GEL LYD+P +D +LRAN ISSLDG ATV G SG + G G Sbjct 12 GPAGTQLTQLTTGAPVDSGELIDLYDFPKNDKIYLRANMISSLDGAATVTGLSGGLGGDG 71 Query 67 DRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRL 126 DR VF +R ADVI+VG GTVR E Y G + V RQ RQ+RGQ EVP +A+VT SG + Sbjct 72 DRAVFAAMRANADVILVGSGTVRAERYHGAHLPVGLRQRRQSRGQDEVPTIAVVTASGAV 131 Query 127 DRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARG 186 D +F +E+AP+V+T+ + A R+ G +++ GD TVD ++ L ARG Sbjct 132 DPSTPLFNESEVAPIVVTSASGAPHVASRVPGAQILVSGDGD---TVDLPAALATLHARG 188 Query 187 LRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTD 246 L R+L EGGP LLGT + ++DELCLTIAP +GG RI +GP +VLT R +L D Sbjct 189 LSRVLCEGGPALLGTLLSAHLVDELCLTIAPTTIGGAGLRITSGPAEVLTGWRRVLLLAD 248 Query 247 DSGYLYTRYV 256 GYL+TRYV Sbjct 249 ADGYLFTRYV 258 >gi|111023823|ref|YP_706795.1| hypothetical protein RHA1_ro06865 [Rhodococcus jostii RHA1] gi|110823353|gb|ABG98637.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Rhodococcus jostii RHA1] Length=262 Score = 195 bits (496), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 112/237 (48%), Positives = 145/237 (62%), Gaps = 6/237 (2%) Query 24 TDGELPQLYDYPDDGT--WLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVI 81 T L LY YP + W+R NF+SS+DG +VDG SGA+ P DR VF LRELADV+ Sbjct 25 TANALRDLYAYPAETPRPWVRVNFVSSIDGAVSVDGVSGALGTPADRLVFETLRELADVV 84 Query 82 VVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPL 141 +VG GTVR+E Y G R+ R+ R A G EVP +A+V+ LD +FT TE+AP+ Sbjct 85 LVGAGTVRVENYGGARIHAEGRRRRVASGMPEVPPIAVVSARAHLDPQSRLFTDTEVAPI 144 Query 142 VLTTTAVADDTRQR-LAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLG 200 V+T T AD R R LA I +GD G + L++ L GLRR+L EGGP+L G Sbjct 145 VVTCTD-ADPGRVRALADAGARIVTAGD--GQISGDGLIAALEHLGLRRVLCEGGPSLFG 201 Query 201 TFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 DV+DE+CLT AP +VGG A R+ T PG + M AH+LTD G + TR+V+ Sbjct 202 RLTADDVVDEVCLTTAPVLVGGTAGRVATAPGARIIAMTPAHILTDTDGTVLTRWVR 258 >gi|226366259|ref|YP_002784042.1| hypothetical protein ROP_68500 [Rhodococcus opacus B4] gi|226244749|dbj|BAH55097.1| hypothetical protein [Rhodococcus opacus B4] Length=262 Score = 188 bits (477), Expect = 8e-46, Method: Compositional matrix adjust. Identities = 109/237 (46%), Positives = 142/237 (60%), Gaps = 6/237 (2%) Query 24 TDGELPQLYDYPDDGT--WLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVI 81 T L LY YP + W+R NF+SS+DG +VDG SGA+ P D VF LRELADV+ Sbjct 25 TANSLRALYAYPAETPRPWIRVNFVSSIDGAVSVDGVSGALGTPADALVFETLRELADVV 84 Query 82 VVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPL 141 +VG GTVR E Y G R+G R R A G EVP +A+V+ LD +FT TE+AP+ Sbjct 85 LVGAGTVRAENYGGARIGAEGRGRRVASGMPEVPPIAVVSARAHLDPHARLFTDTEVAPI 144 Query 142 VLTTTAVADDTRQR-LAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLG 200 V+ T A AD R R LA I +G+ T + L++ L GLRR+L EGGP+L G Sbjct 145 VV-TCADADPARIRDLAAAGARIVTAGEVQITSEG--LIAALDDLGLRRVLCEGGPSLFG 201 Query 201 TFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 + D +DE+CLT AP + G A R+ T PG +T M AH+LTD G + TR+V+ Sbjct 202 QLIADDSVDEVCLTTAPVLASGTAGRVATAPGARITAMTPAHILTDTDGTVLTRWVR 258 >gi|312139475|ref|YP_004006811.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase ribd [Rhodococcus equi 103S] gi|325672635|ref|ZP_08152331.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Rhodococcus equi ATCC 33707] gi|311888814|emb|CBH48126.1| putative 5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [Rhodococcus equi 103S] gi|325556512|gb|EGD26178.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Rhodococcus equi ATCC 33707] Length=262 Score = 188 bits (477), Expect = 8e-46, Method: Compositional matrix adjust. Identities = 115/239 (49%), Positives = 142/239 (60%), Gaps = 8/239 (3%) Query 23 LTDGELPQLYDYPD--DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADV 80 L+D L LY YPD D W+R NF+SS+DG TVDG S + P D+ VF +LRELADV Sbjct 27 LSDDHLRSLYGYPDRLDRPWIRTNFVSSIDGAVTVDGVSAGLGTPADKRVFAVLRELADV 86 Query 81 IVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAP 140 +VVG GTVR E Y G R R+ G + VP +A+VT S RLD +FT T + P Sbjct 87 VVVGAGTVRSENYGGARTDADSAARRERSGLAAVPPIAVVTASARLDPASRLFTDTTVPP 146 Query 141 LVLTTTAVADDTRQRL--AGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTL 198 LVLT+ A QRL AG A+V + + G D +V+ L RGLRR+L EGGP L Sbjct 147 LVLTSAAADASRVQRLRDAG-ADVEIVAEREIGGTD---VVAALGLRGLRRVLCEGGPGL 202 Query 199 LGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 GT + V+DELCLT +P +VGG A RI T M AHVL DD G L TR+V+ Sbjct 203 FGTLIADGVVDELCLTTSPVLVGGAAGRIAHSSIASPTAMSRAHVLADDDGTLLTRWVR 261 >gi|269126013|ref|YP_003299383.1| bifunctional deaminase-reductase domain-containing protein [Thermomonospora curvata DSM 43183] gi|268310971|gb|ACY97345.1| bifunctional deaminase-reductase domain protein [Thermomonospora curvata DSM 43183] Length=229 Score = 171 bits (432), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 106/230 (47%), Positives = 136/230 (60%), Gaps = 15/230 (6%) Query 27 ELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGVG 86 EL + Y YP +G WLRAN I+SLDG A VDG SG + PGDR +F LR +ADV++VG G Sbjct 10 ELQKAYAYPPEGVWLRANMIASLDGAAWVDGRSGGLGSPGDRRLFAALRAMADVVIVGAG 69 Query 87 TVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTT 146 TVR EGY VR G Q + P LAIV+R LD D VFT + ++LT Sbjct 70 TVRAEGYGPVRPGP----------QGQAPPLAIVSRRLDLDLDSPVFTEPKARTVLLTVQ 119 Query 147 AVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVERD 206 A + + +AEVI +G+D +D + V +LAARG RR+L EGGP +L Sbjct 120 AAPPERLRAAERVAEVI-MAGED--GIDFSRAVRELAARGHRRLLCEGGPAVLARAAADG 176 Query 207 VLDELCLTIAPYVVGGLARRIVTGPGQVLT-RMRCAHVLTDDSGYLYTRY 255 VLDELCLT++P +V G RI+ GP RMR A V +D G+L+ RY Sbjct 177 VLDELCLTLSPMLVAGDPSRILAGPPLPRPLRMRPASVYEED-GFLFLRY 225 >gi|333919455|ref|YP_004493036.1| riboflavin biosynthesis protein RibD domain-containing protein [Amycolicicoccus subflavus DQS3-9A1] gi|333481676|gb|AEF40236.1| Riboflavin biosynthesis protein RibD domain protein [Amycolicicoccus subflavus DQS3-9A1] Length=255 Score = 169 bits (429), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 103/235 (44%), Positives = 142/235 (61%), Gaps = 2/235 (0%) Query 25 DGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVG 84 D EL Q+Y YP+ +WLR NF+SS+DG T G SGA++ D+ +F LLRELADV+VVG Sbjct 16 DAELRQIYRYPE-SSWLRVNFVSSIDGAVTSGGLSGALSSGTDKHLFGLLRELADVVVVG 74 Query 85 VGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLT 144 GTVR E Y GV + RQ R GQS VPQ+A+V+ S LD +FT T + PL+ T Sbjct 75 AGTVRAENYGGVALSDDARQRRLEAGQSAVPQIAVVSASANLDPHSRLFTDTAVPPLIFT 134 Query 145 T-TAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFV 203 + A A AEV D GT+D ++ L ++ ++L EGGP+LLG + Sbjct 135 SENAPHGAIAALRAAGAEVNEIRLDPTGTLDSHEILRILRSQNRGKVLCEGGPSLLGALL 194 Query 204 ERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVKT 258 D++D+LCL+I P + G + RI TG RMR AH L+ D G ++TR+V++ Sbjct 195 AADLVDDLCLSITPVLTAGSSGRIATGELPQQRRMRLAHTLSGDDGTVFTRWVRS 249 >gi|134098447|ref|YP_001104108.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Saccharopolyspora erythraea NRRL 2338] gi|133911070|emb|CAM01183.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Saccharopolyspora erythraea NRRL 2338] Length=244 Score = 167 bits (423), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 104/236 (45%), Positives = 138/236 (59%), Gaps = 5/236 (2%) Query 25 DGELPQLYDYPD--DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIV 82 D EL Q Y YP+ + W+R NF+SSLDG T+ G S ++ P D+ V L+R+L+DV++ Sbjct 8 DDELEQFYAYPEALERPWVRVNFVSSLDGAVTIKGRSRGLSAPEDQRVLGLIRDLSDVVL 67 Query 83 VGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLV 142 VGV T +EGY GV+ V+ + R G S VP +A+VTRS L D + T T + P+V Sbjct 68 VGVSTAVLEGYRGVKRTEVRSERRSRLGLSPVPPIALVTRSCSLPVDSPLLTDTLVPPIV 127 Query 143 LTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTF 202 LT A D R LA + +GD+ VD ++ L RGLRRI EGGPTL G+ Sbjct 128 LTCQAAPADRRAALADAGADVVVAGDE--QVDLPAALAALDERGLRRIGCEGGPTLFGSL 185 Query 203 VERDVLDELCLTIAPYVVGGLARRIVTGPG-QVLTRMRCAHVLTDDSGYLYTRYVK 257 VE D++DELCLT++P + GG A RI G G V RMR L D L RY + Sbjct 186 VESDLVDELCLTMSPLLAGGDAGRIAKGTGVGVPRRMRLLSALHTDESLLLLRYAR 241 >gi|291003336|ref|ZP_06561309.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Saccharopolyspora erythraea NRRL 2338] Length=250 Score = 167 bits (423), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 104/236 (45%), Positives = 138/236 (59%), Gaps = 5/236 (2%) Query 25 DGELPQLYDYPD--DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIV 82 D EL Q Y YP+ + W+R NF+SSLDG T+ G S ++ P D+ V L+R+L+DV++ Sbjct 14 DDELEQFYAYPEALERPWVRVNFVSSLDGAVTIKGRSRGLSAPEDQRVLGLIRDLSDVVL 73 Query 83 VGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLV 142 VGV T +EGY GV+ V+ + R G S VP +A+VTRS L D + T T + P+V Sbjct 74 VGVSTAVLEGYRGVKRTEVRSERRSRLGLSPVPPIALVTRSCSLPVDSPLLTDTLVPPIV 133 Query 143 LTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTF 202 LT A D R LA + +GD+ VD ++ L RGLRRI EGGPTL G+ Sbjct 134 LTCQAAPADRRAALADAGADVVVAGDE--QVDLPAALAALDERGLRRIGCEGGPTLFGSL 191 Query 203 VERDVLDELCLTIAPYVVGGLARRIVTGPG-QVLTRMRCAHVLTDDSGYLYTRYVK 257 VE D++DELCLT++P + GG A RI G G V RMR L D L RY + Sbjct 192 VESDLVDELCLTMSPLLAGGDAGRIAKGTGVGVPRRMRLLSALHTDESLLLLRYAR 247 >gi|226306344|ref|YP_002766304.1| hypothetical protein RER_28570 [Rhodococcus erythropolis PR4] gi|226185461|dbj|BAH33565.1| conserved hypothetical protein [Rhodococcus erythropolis PR4] Length=249 Score = 166 bits (419), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 95/244 (39%), Positives = 136/244 (56%), Gaps = 13/244 (5%) Query 22 YLTDG---ELPQLYDYPDDGT--WLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRE 76 Y T G EL LY YP++ + W+R NF+SS+DG +VDG S + P D+ VF +LRE Sbjct 6 YFTPGHEDELRGLYAYPENLSQPWMRVNFVSSIDGCVSVDGVSHGLGTPADKSVFGILRE 65 Query 77 LADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRT 136 L DV+VVG GT R E Y GV++ R R+A G + VPQ+ +V+ +D + + T Sbjct 66 LCDVVVVGAGTARAENYGGVQISDAARARRKAGGLAPVPQILVVSAHASIDPESRLLRDT 125 Query 137 EMAPLVLTTTAVADDTRQRL---AGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTE 193 E+ P+++ +A L EV G +D A L+AR LRR+L E Sbjct 126 EIPPILVVGSAADSAAISALRSAGAQVEVTDSPNVSSGDIDRA-----LSARKLRRVLCE 180 Query 194 GGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYT 253 GGP+L G +E + +DELC+T +P +VG RI P + T M AH+L D G + T Sbjct 181 GGPSLFGQLIEDNAVDELCITTSPQLVGSKVGRISLSPNAMPTSMHPAHILGDSDGTILT 240 Query 254 RYVK 257 R+V+ Sbjct 241 RWVR 244 >gi|229491248|ref|ZP_04385074.1| riboflavin biosynthesis protein RibD domain protein [Rhodococcus erythropolis SK121] gi|229321787|gb|EEN87582.1| riboflavin biosynthesis protein RibD domain protein [Rhodococcus erythropolis SK121] Length=249 Score = 165 bits (418), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 95/244 (39%), Positives = 135/244 (56%), Gaps = 13/244 (5%) Query 22 YLTDG---ELPQLYDYPDDGT--WLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRE 76 Y T G EL LY YP++ + W+R NF+SS+DG VDG SG + P D+ VF +LRE Sbjct 6 YFTQGHDDELRGLYAYPENLSQPWMRVNFVSSIDGCVAVDGVSGGLGTPADKSVFGILRE 65 Query 77 LADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRT 136 L DV+VVG GT R E Y GV++ R R A G + VP + +V+ +D + + T Sbjct 66 LCDVVVVGAGTARAENYGGVQVSDEARARRTADGLAPVPPILVVSAHASIDSESRLLRDT 125 Query 137 EMAPLVLT---TTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTE 193 E+ P+++ + A + EV G +D A L+AR LRR+L E Sbjct 126 EVPPILVVGRDADSAAISALRSAGAQVEVTDSPNVTSGDIDRA-----LSARKLRRVLCE 180 Query 194 GGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYT 253 GGP+L G +E + +DELC+T +P +VG RI P + T MR AH+L D G + T Sbjct 181 GGPSLFGQLIEDNAVDELCITTSPQLVGSKVGRISLSPNAMPTAMRPAHILGDTDGTILT 240 Query 254 RYVK 257 R+V+ Sbjct 241 RWVR 244 >gi|88856373|ref|ZP_01131032.1| hypothetical protein A20C1_00495 [marine actinobacterium PHSC20C1] gi|88814457|gb|EAR24320.1| hypothetical protein A20C1_00495 [marine actinobacterium PHSC20C1] Length=255 Score = 164 bits (414), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 112/254 (45%), Positives = 145/254 (58%), Gaps = 10/254 (3%) Query 7 LGAADTPLRLLSSVHYLTDGELPQLYDYPDDGT-WLRANFISSLDGGATVDGTSGAMAGP 65 L AA + + +L S + LTD +L Y D WLRANF+SS+DG AT +GTSG + Sbjct 2 LVAASSEIHVLQSGNVLTDEQLLASYAVADRTMPWLRANFVSSIDGAATHEGTSGGLGTE 61 Query 66 GDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGR 125 D VF LLR LADVIVVG GTVR EGY + + R + G S P A+V+ S R Sbjct 62 ADGRVFALLRRLADVIVVGAGTVRQEGYRNLALDDDAVAWRTSNGLSAQPPFALVSASLR 121 Query 126 LD-RDMAVF-TRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLA 183 ++ D+A + TR P V+TT + + R RL +AEVI +GD+ VD L LA Sbjct 122 IEPDDLATYATR----PFVITTQSAPAEARARLEAVAEVI-VAGDE--QVDTVELKRTLA 174 Query 184 ARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHV 243 RG + EGGPTL T + + V+DELCLT++P + GG ARRIV M AHV Sbjct 175 ERGYPQQHGEGGPTLFATMIGQGVVDELCLTVSPRLEGGSARRIVDAAEATPQAMSLAHV 234 Query 244 LTDDSGYLYTRYVK 257 L+ G L RYV+ Sbjct 235 LSAADGTLLLRYVR 248 >gi|54025702|ref|YP_119944.1| hypothetical protein nfa37320 [Nocardia farcinica IFM 10152] gi|54017210|dbj|BAD58580.1| putative deaminase/reductase [Nocardia farcinica IFM 10152] Length=259 Score = 163 bits (413), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 93/237 (40%), Positives = 134/237 (57%), Gaps = 9/237 (3%) Query 28 LPQLYDYPD--DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGV 85 L LY YP W+R NF++S+DG AT + A+ P D+ VF LLR+LADV++VG Sbjct 24 LADLYAYPMGLADPWVRVNFVASIDGAATSGDVTAALGTPADKRVFKLLRDLADVVLVGA 83 Query 86 GTVRIEGYSGVRMGVVQRQ--HRQARG---QSEVPQLAIVTRSGRLDRDMAVFTRTEMAP 140 GTVR E Y G R +R+ H ++RG P +A+VT + L+ + T T + P Sbjct 84 GTVRTENYGGARTDAARRRSLHDRSRGGHPDGAPPPIAVVTATAALEPTCRLLTDTTVPP 143 Query 141 LVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLG 200 L++T A D +++LA + +G+ V L++ LA RGL R+L EGGP L G Sbjct 144 LIITAAAAPADRKEKLAAAGAEVIEAGE--AAVTPKALLAALAERGLHRVLCEGGPHLFG 201 Query 201 TFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 +E D++DELCLT AP +VGG A RI + M H++ DD G + TR+ + Sbjct 202 QLIEADLVDELCLTTAPVLVGGTAGRISLSAREFHQHMHRRHMILDDDGTVLTRWAR 258 >gi|50955356|ref|YP_062644.1| hypothetical protein Lxx17960 [Leifsonia xyli subsp. xyli str. CTCB07] gi|50951838|gb|AAT89539.1| diaminohydroxyphosphoribosylaminopyrimidine deaminase [Leifsonia xyli subsp. xyli str. CTCB07] Length=248 Score = 160 bits (404), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 101/239 (43%), Positives = 135/239 (57%), Gaps = 7/239 (2%) Query 23 LTDGELPQLYDYPDDG--TWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADV 80 L D EL LY +WLR NF++SLDG AT G SG ++ D+ VF++LR L DV Sbjct 10 LDDTELAALYTAGTGAGPSWLRVNFVASLDGAATEQGLSGGLSDDADKRVFDILRRLCDV 69 Query 81 IVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAP 140 +VVG GT+R EGY +R+ ++ R+A G +E P AIV+ LD +F P Sbjct 70 VVVGAGTIRAEGYGAMRVDAASQRARRADGLTEHPVFAIVSAVLDLDPAGPIFREAPERP 129 Query 141 LVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLG 200 LVLT+ R+ LA +A+V+ C V+ +LV +LAARGLRRI EGGP L G Sbjct 130 LVLTSERSRAGAREALAEVADVVVCGAQ---RVEPRLLVRELAARGLRRIHCEGGPRLFG 186 Query 201 TFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVL-TRMRCAHVLTDDSGYLYTRYVKT 258 + V+DELCLT++P + G A RI G + MR AHVL + L RYV+ Sbjct 187 DLLAGGVVDELCLTLSPRLEAGSATRIAVGAAPIEPVGMRLAHVLHSED-TLLLRYVRA 244 >gi|291301495|ref|YP_003512773.1| bifunctional deaminase-reductase domain-containing protein [Stackebrandtia nassauensis DSM 44728] gi|290570715|gb|ADD43680.1| bifunctional deaminase-reductase domain protein [Stackebrandtia nassauensis DSM 44728] Length=242 Score = 159 bits (402), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 97/240 (41%), Positives = 134/240 (56%), Gaps = 5/240 (2%) Query 18 SSVHYLTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLREL 77 S + L EL Y P WLR NF+SS DG V+G S A++G D VF +LR Sbjct 5 SELSSLDQSELTDWY-APSAPDWLRVNFVSSADGAVEVNGDSKALSGEDDMRVFRILRMR 63 Query 78 ADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTE 137 DV+VVG GTVR +GY +R+ + + R+A G + P +A+V+RSG LD D +F Sbjct 64 CDVLVVGAGTVRTDGYRALRLSQDRVEWRRAAGLPDHPVMAVVSRSGILDLDTPLFREAP 123 Query 138 MAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPT 197 + P+V+T D +RLA L++V G+VD A +L RGLR+IL EGGP Sbjct 124 VRPIVITPE---DLDAKRLAELSDVADVVAAGTGSVDFAEAFERLRQRGLRQILCEGGPH 180 Query 198 LLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 + G ++DELCLT++P++ G + RI GP L RM AH L + G L RY + Sbjct 181 VFGEITAAGLVDELCLTLSPHLAGAGSGRITAGPPSPLKRMHLAHCLHAN-GNLLLRYTR 239 >gi|284033054|ref|YP_003382985.1| bifunctional deaminase-reductase domain-containing protein [Kribbella flavida DSM 17836] gi|283812347|gb|ADB34186.1| bifunctional deaminase-reductase domain protein [Kribbella flavida DSM 17836] Length=242 Score = 159 bits (402), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 96/239 (41%), Positives = 138/239 (58%), Gaps = 9/239 (3%) Query 23 LTDGELPQLYDYPDDGT-WLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVI 81 LT+ E+ Y D LR NF++S+DG V+G S A++G D+ +F LR L+DV+ Sbjct 7 LTEAEVIAAYQVADRSVPHLRCNFVTSIDGAMEVEGKSKALSGAADQEIFGKLRMLSDVV 66 Query 82 VVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMA--VFTRTEMA 139 +VG GTVRIEGY +R+ +R+ R+A+G E P LAIV S RLD D A + Sbjct 67 LVGAGTVRIEGYRPLRLSAARREWRRAQGLPENPTLAIV--SSRLDLDPASPFLAEAPVR 124 Query 140 PLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLL 199 P+V T TA D R+ LA +A+V+ C VD ++ L RGL ++L+EGGP LL Sbjct 125 PIVFTHTASPLDAREALAEVADVVVCGR---AGVDLRAVMKTLVERGLPQVLSEGGPHLL 181 Query 200 GTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTR-MRCAHVLTDDSGYLYTRYVK 257 G D++DE+CL++AP + G + RI GP R +L D G+L+ RY++ Sbjct 182 GALTAADLVDEMCLSLAPVLAGPGSGRITAGPTATAIRSFALRSLLAGDDGFLFFRYLR 240 >gi|257056391|ref|YP_003134223.1| pyrimidine reductase, riboflavin biosynthesis [Saccharomonospora viridis DSM 43017] gi|256586263|gb|ACU97396.1| pyrimidine reductase, riboflavin biosynthesis [Saccharomonospora viridis DSM 43017] Length=258 Score = 157 bits (398), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 105/247 (43%), Positives = 143/247 (58%), Gaps = 10/247 (4%) Query 12 TPLRLLSSVHYLTDGELPQLYDYPDD--GTWLRANFISSLDGGATVDGTSGAMAGPGDRF 69 TP+ L S LTD EL +LYDYP D W++ NF+SS DG +V S ++ P D+ Sbjct 11 TPVELSS----LTDTELERLYDYPPDLARPWVQVNFVSSADGAVSVSDRSAGLSHPADKR 66 Query 70 VFNLLRELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRD 129 VF L R+LADVI+VG GT R E Y GV+ ++ + R+ G SE+P +A+VT L D Sbjct 67 VFGLGRDLADVILVGAGTARAERYRGVKAHELRLERRRRLGLSELPPIAVVTGRCDLTPD 126 Query 130 MAVFTRTEMAPLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRR 189 + T T + PLVLTT + L + +G++ TVD + ++ L RGLRR Sbjct 127 DPLVTDTIVPPLVLTTQRAPRHRKDALTEAGVDVVEAGEE--TVDPRLALAALDERGLRR 184 Query 190 ILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTG-PGQVLTRMRCAHVLTDDS 248 + EGGP L V D++D+LCLTIAP + G A RIVTG P + +R A VL +D Sbjct 185 VDCEGGPRLFAALVAADLVDQLCLTIAPLLAGAGADRIVTGVPSPLPRSLRLASVLHED- 243 Query 249 GYLYTRY 255 G+L RY Sbjct 244 GFLMLRY 250 >gi|329940196|ref|ZP_08289478.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Streptomyces griseoaurantiacus M045] gi|329301022|gb|EGG44918.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Streptomyces griseoaurantiacus M045] Length=300 Score = 157 bits (398), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 109/244 (45%), Positives = 137/244 (57%), Gaps = 14/244 (5%) Query 21 HYLTDGELPQLYDYPDDG-----TWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLR 75 H T EL Y YP G WLRAN +S+LDG A +G S +++G D +F +LR Sbjct 59 HAWTFDELAAAYAYPVAGGGRPRPWLRANMVSTLDGAAQHEGRSKSISGAADMRIFGVLR 118 Query 76 ELADVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTR 135 LADV+VVG TVR EGY R+A GQ P +A+V+ LD + +FT Sbjct 119 ALADVVVVGAETVRREGYGPAGARAEAAASRKAAGQGPAPAIAVVSAGLGLDFTLPLFTS 178 Query 136 TEMAPLVLTTTAVADDTR---QRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILT 192 + P +L T A AD R AG ++A G VD A V LA RGL R+LT Sbjct 179 PPV-PTLLLTGAAADPARVAEAERAGAHVILAGEGTG---VDPARAVRALAERGLTRLLT 234 Query 193 EGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPG-QVLTRMRCAHVLTDDSGYL 251 EGGP LLG FV DVLDELCLT+AP +V G A+RI GP +V R R VL ++ G+L Sbjct 235 EGGPRLLGQFVAADVLDELCLTVAPVMVAGGAQRIGGGPEVRVPRRFRPVSVL-EEEGFL 293 Query 252 YTRY 255 +TRY Sbjct 294 FTRY 297 >gi|111221547|ref|YP_712341.1| hypothetical protein FRAAL2113 [Frankia alni ACN14a] gi|111149079|emb|CAJ60762.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase (Riboflavin biosynthesis protein ribD) [Frankia alni ACN14a] Length=282 Score = 153 bits (387), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 102/233 (44%), Positives = 134/233 (58%), Gaps = 9/233 (3%) Query 27 ELPQLYDYPDDG---TWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVV 83 +L + Y YP +++RANF+SS+DG A V G SG + G DR VF LLR L+DV++V Sbjct 53 DLDEAYAYPPAAGQTSYVRANFVSSVDGAAEVGGRSGPLGGEADRRVFQLLRWLSDVVLV 112 Query 84 GVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVL 143 G GTVR E Y V + +R RQA G + VP +A++T + LD +F E+ P+VL Sbjct 113 GAGTVRHENYGPVIVPPERRDRRQAAGLAAVPPIAVITATAGLDPGARLFD-AEVRPIVL 171 Query 144 TTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFV 203 T A RQ LA +AEV+ C TVD A ++ LA RG+ R+LTEGGP L Sbjct 172 TCDAAPPAKRQALAAVAEVVLCGET---TVDPAAALAALAERGMTRVLTEGGPLLHAQLA 228 Query 204 ERDVLDELCLTIAPYVVGGLARRIVTGPGQV-LTRMRCAHVLTDDSGYLYTRY 255 +LDELCLT+AP + G IV GP MR VL +D G L+ RY Sbjct 229 GAGLLDELCLTVAPMLAGPGRMGIVEGPPWPEPATMRLVQVLAED-GNLFLRY 280 >gi|326444043|ref|ZP_08218777.1| hypothetical protein SclaA2_23394 [Streptomyces clavuligerus ATCC 27064] Length=275 Score = 152 bits (385), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 105/236 (45%), Positives = 135/236 (58%), Gaps = 8/236 (3%) Query 27 ELPQLYDYPD---DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVV 83 EL Y YP DG WLRAN +SSLDG A +G S ++ D +F LR LAD +VV Sbjct 42 ELADAYAYPALPADGAWLRANMVSSLDGAAQHEGRSQPLSSDADMRIFGTLRALADAVVV 101 Query 84 GVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVL 143 G TVR EGY R R+A GQ P +A+V+ S LD + +FT + P ++ Sbjct 102 GAETVRREGYRPARAREAFAARRRAAGQGPAPAIAVVSASLALDFSLPLFTE-PLVPTLV 160 Query 144 TTTAVADDTRQRLAGLAEV-IACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTF 202 T A A R R A A V + +G+ G V+ A V LA +GLRR+LTEGGP LLG F Sbjct 161 LTGAAAPPERLREAERAGVRVLIAGEGRG-VEPATAVRVLAEQGLRRLLTEGGPRLLGHF 219 Query 203 VERDVLDELCLTIAPYVVGGLARRIVTGPGQ-VLTRMRCAHVLTDDSGYLYTRYVK 257 + VLDELCLT++P V G ++RI GP V R A VL +D G+L+TRY + Sbjct 220 MAAGVLDELCLTLSPTVTAGDSQRIAHGPAMAVPARFTLAGVLEED-GFLFTRYQR 274 >gi|294815697|ref|ZP_06774340.1| Bifunctional deaminase-reductase domain-containing protein [Streptomyces clavuligerus ATCC 27064] gi|294328296|gb|EFG09939.1| Bifunctional deaminase-reductase domain-containing protein [Streptomyces clavuligerus ATCC 27064] Length=281 Score = 152 bits (384), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 105/236 (45%), Positives = 135/236 (58%), Gaps = 8/236 (3%) Query 27 ELPQLYDYPD---DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVV 83 EL Y YP DG WLRAN +SSLDG A +G S ++ D +F LR LAD +VV Sbjct 48 ELADAYAYPALPADGAWLRANMVSSLDGAAQHEGRSQPLSSDADMRIFGTLRALADAVVV 107 Query 84 GVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVL 143 G TVR EGY R R+A GQ P +A+V+ S LD + +FT + P ++ Sbjct 108 GAETVRREGYRPARAREAFAARRRAAGQGPAPAIAVVSASLALDFSLPLFTE-PLVPTLV 166 Query 144 TTTAVADDTRQRLAGLAEV-IACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTF 202 T A A R R A A V + +G+ G V+ A V LA +GLRR+LTEGGP LLG F Sbjct 167 LTGAAAPPERLREAERAGVRVLIAGEGRG-VEPATAVRVLAEQGLRRLLTEGGPRLLGHF 225 Query 203 VERDVLDELCLTIAPYVVGGLARRIVTGPGQ-VLTRMRCAHVLTDDSGYLYTRYVK 257 + VLDELCLT++P V G ++RI GP V R A VL +D G+L+TRY + Sbjct 226 MAAGVLDELCLTLSPTVTAGDSQRIAHGPAMAVPARFTLAGVLEED-GFLFTRYQR 280 >gi|331696725|ref|YP_004332964.1| bifunctional deaminase-reductase domain-containing protein [Pseudonocardia dioxanivorans CB1190] gi|326951414|gb|AEA25111.1| bifunctional deaminase-reductase domain protein [Pseudonocardia dioxanivorans CB1190] Length=256 Score = 152 bits (383), Expect = 6e-35, Method: Compositional matrix adjust. Identities = 100/236 (43%), Positives = 130/236 (56%), Gaps = 18/236 (7%) Query 25 DGELPQLYDYPD--DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIV 82 D L + Y YPD +R NF++SLDG +VDG SG + D+ VF +LR LADV++ Sbjct 16 DAALLRHYAYPDGLSAPRVRVNFVASLDGAVSVDGLSGGLGSAADKAVFGVLRRLADVVL 75 Query 83 VGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLV 142 VG GTVR EGY G R R G++ P +A+VT S LD +FT T +AP+V Sbjct 76 VGAGTVRAEGYRGAR--------RPTVGRALPPPIAVVTGSAGLDPGARLFTDTAVAPIV 127 Query 143 LTTTAVADDTRQRL-AGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGT 201 LTT + R L A A+V+ P T L+++L RGL R+L EGGP L G Sbjct 128 LTTAGAPGERRDALRAAGADVVELPDLAPPT-----LLAELGRRGLHRVLCEGGPALHGA 182 Query 202 FVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 D +DELCLT++P +VGG A RI TGP + R C D G L YV+ Sbjct 183 LAAADAVDELCLTLSPTLVGGDAGRIATGPSTM--RPMCLAGALLDPGALLLHYVR 236 >gi|254387285|ref|ZP_05002544.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Streptomyces sp. Mg1] gi|194346089|gb|EDX27055.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Streptomyces sp. Mg1] Length=262 Score = 151 bits (382), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 98/232 (43%), Positives = 129/232 (56%), Gaps = 4/232 (1%) Query 27 ELPQLYDYP---DDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVV 83 EL + Y YP D WLRAN +S+LDG A +G S ++G D +F LR LADV+VV Sbjct 29 ELAEAYAYPPLSQDAHWLRANMVSTLDGAAQHEGRSQPISGESDMRIFGTLRALADVVVV 88 Query 84 GVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVL 143 G TVR EGY R R+A GQ P +A++T S LD + ++T + LV+ Sbjct 89 GAETVRQEGYRPARARADFAARREAAGQGPAPAIAVITASMDLDFSLPLYTSPLVPTLVI 148 Query 144 TTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFV 203 T +A D R A A + VD A V +LA RG+RR LTEGGP LLG FV Sbjct 149 TGSAAPSD-RVAAATAAGAEVVVAGEGAAVDPARAVRELALRGMRRQLTEGGPRLLGQFV 207 Query 204 ERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRY 255 D LDELCLTI+P + G A+RI GP + A + +++G+L+T Y Sbjct 208 AADALDELCLTISPMLTAGDAQRISGGPSVAVPHRLAAASVLEEAGFLFTSY 259 >gi|315502712|ref|YP_004081599.1| bifunctional deaminase-reductase domain-containing protein [Micromonospora sp. L5] gi|315409331|gb|ADU07448.1| bifunctional deaminase-reductase domain protein [Micromonospora sp. L5] Length=267 Score = 151 bits (381), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 97/238 (41%), Positives = 128/238 (54%), Gaps = 6/238 (2%) Query 23 LTDGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIV 82 LTD +L LY G LR NF++S DG T+DG S ++G D+ VF LLR L D +V Sbjct 19 LTDPQLTALYGR-TAGPHLRVNFVASADGAVTLDGYSAGLSGEPDKRVFGLLRMLCDGLV 77 Query 83 VGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLV 142 V GT+R EGY VR+ +R R+ +G +E P L +V+ S LD A F + P+V Sbjct 78 VAAGTLRHEGYRAVRLSPERRAWRREQGLAEFPTLVVVSGSLDLDPAQAAFADAPVRPIV 137 Query 143 LTTTAVADDTRQRLAGLAEVIAC---SGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLL 199 LT LA +A+VI C D PG VD +++L RGL ++L EGGP L Sbjct 138 LTHADAVPP--PGLADVADVIRCGTDQADAPGRVDLVAGLAELRRRGLGQLLCEGGPHLF 195 Query 200 GTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 G D++DELCLT+AP + G RI G V + HVL G L RYV+ Sbjct 196 GALTAADLVDELCLTVAPLLAGAGPGRITAGDASVPRHLPLRHVLAAADGVLMLRYVR 253 >gi|311898892|dbj|BAJ31300.1| hypothetical protein KSE_55250 [Kitasatospora setae KM-6054] Length=262 Score = 150 bits (380), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 97/231 (42%), Positives = 127/231 (55%), Gaps = 5/231 (2%) Query 28 LPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGVGT 87 L + Y YP+ G WLRAN ++SLDG A +DG S ++ D+ +F +LR L DV++VG T Sbjct 18 LARAYAYPEAGRWLRANMVTSLDGAARLDGLSEGLSSAADKRIFGVLRALCDVVLVGAET 77 Query 88 VRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTTA 147 VR EGY R + R A GQ P +A+V+RS LD +FT PLV T Sbjct 78 VRAEGYRPGRARPEFAERRAAAGQPPAPVIAVVSRSLELDLSAPLFTE----PLVPTVVV 133 Query 148 VADDTRQ-RLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVERD 206 D RLA +A G+VD V+ LA RG RR LTEGGP LL Sbjct 134 TTVDAPPARLAEVAAAAEVVTAGTGSVDLPRAVAALAGRGWRRQLTEGGPRLLAQLAADG 193 Query 207 VLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 +LDELCL++AP V G + RIV GPG R L ++ G+L+TRY++ Sbjct 194 LLDELCLSVAPLVTAGDSPRIVNGPGIPDVRPMRLVSLIEEKGFLFTRYLR 244 >gi|320007797|gb|ADW02647.1| bifunctional deaminase-reductase domain protein [Streptomyces flavogriseus ATCC 33331] Length=257 Score = 150 bits (380), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 100/232 (44%), Positives = 129/232 (56%), Gaps = 2/232 (0%) Query 27 ELPQLYDYPDDG-TWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGV 85 EL Y YP WLRAN +S+LDG A DG S ++ D VF LR LAD +VVG Sbjct 26 ELADAYAYPGGRRPWLRANMVSTLDGAAQHDGRSQGISCAADMRVFGTLRGLADAVVVGA 85 Query 86 GTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTT 145 TVR+EGY R R+A GQ P +A+V+ S LD + +F + LV+T Sbjct 86 ETVRLEGYRPARAREAFAARREAEGQGPAPAVAVVSASLDLDFSLPLFVSPLVPTLVITG 145 Query 146 TAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVER 205 +A D R R A + D VD A V++LAARGL R+LTEGGP LLG FV Sbjct 146 SAAPSD-RVRAARESGAEVVFAGDGSAVDPARAVAELAARGLGRLLTEGGPRLLGQFVAA 204 Query 206 DVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVK 257 VLDELCLT++P + G A+RI GP + L +++G+L+TRY K Sbjct 205 GVLDELCLTLSPLLTAGDAQRIAGGPAVPVPERFALVSLLEEAGFLFTRYGK 256 >gi|345009984|ref|YP_004812338.1| bifunctional deaminase-reductase domain-containing protein [Streptomyces violaceusniger Tu 4113] gi|344036333|gb|AEM82058.1| bifunctional deaminase-reductase domain protein [Streptomyces violaceusniger Tu 4113] Length=284 Score = 150 bits (378), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 97/235 (42%), Positives = 130/235 (56%), Gaps = 6/235 (2%) Query 27 ELPQLYDYPD-----DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVI 81 EL Y YP+ G +LRAN +SSLDG A DG S ++ D +F +LR LAD + Sbjct 45 ELADAYAYPEPPHGPSGAFLRANMVSSLDGAAHHDGRSKPLSSDADMRIFGVLRGLADAV 104 Query 82 VVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPL 141 VVG GTVR+EGY R + R A GQ+ P +A+V+ S LD M +FT + + Sbjct 105 VVGAGTVRLEGYRPARAREAFAERRAALGQAPAPAIAVVSASLDLDFSMPLFTEPLVPTV 164 Query 142 VLTTTAVADDTRQRLAGL-AEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLG 200 V+T A A + +R AEV+ G VD A +V+ LA G R+LTEGGPTLL Sbjct 165 VITGAAAAAERIERARAAGAEVVFAGAGPSGRVDAAAVVTALAELGHTRLLTEGGPTLLA 224 Query 201 TFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRY 255 F VLDELCL +AP V G A+RI+ G + +++G+L+TRY Sbjct 225 QFAAAGVLDELCLAVAPLVTAGDAKRIMDGAELGEPEQFTLDSVLEEAGFLFTRY 279 >gi|258653701|ref|YP_003202857.1| bifunctional deaminase-reductase domain-containing protein [Nakamurella multipartita DSM 44233] gi|258556926|gb|ACV79868.1| bifunctional deaminase-reductase domain protein [Nakamurella multipartita DSM 44233] Length=253 Score = 149 bits (377), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 101/235 (43%), Positives = 139/235 (60%), Gaps = 12/235 (5%) Query 25 DGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVG 84 D EL LY +P +RAN I+SLDGGA +DG SG + DR +F +LR+LADVI+VG Sbjct 26 DDELAALYAWPTATPHVRANMITSLDGGAALDGRSGGLGNEADRELFAVLRDLADVILVG 85 Query 85 VGTVRIEGYSGVRMGVVQRQHRQARGQS-EVPQLAIVTRSGRLDRDMAVFTRTEMAPLVL 143 GTVR E Y G+R + R+ G+S + P +A+VTR G LD D+ +FT T+ P+V+ Sbjct 86 AGTVRTEQYGGIRFDPDRLARRRRWGRSKQPPPIAVVTRRG-LDADLPLFTDTQTRPIVI 144 Query 144 TTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFV 203 T A A +R+ A+ + D+ VD A V LA RGL RI EGGP LLG + Sbjct 145 TPQAAA----ERVPPTADALIAGTDE---VDLAAAVRGLADRGLGRIHCEGGPALLGDLI 197 Query 204 ERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSG-YLYTRYVK 257 RD+LDE CLTIAP ++G A R++ P + + L G +L+ RY++ Sbjct 198 ARDLLDECCLTIAPVLLGSAATRLL--PIDLAAPVAWTPALLRIGGAHLFARYLR 250 >gi|297156476|gb|ADI06188.1| hypothetical protein SBI_03067 [Streptomyces bingchenggensis BCW-1] Length=271 Score = 149 bits (377), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 95/237 (41%), Positives = 126/237 (54%), Gaps = 9/237 (3%) Query 27 ELPQLYDYPD--------DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELA 78 EL + Y YPD WLRAN +SSLDG A DG S ++ D +F +LR LA Sbjct 31 ELAEAYAYPDLPAGPGRPAAAWLRANMVSSLDGAAHHDGRSQQLSSAADMRIFGVLRGLA 90 Query 79 DVIVVGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEM 138 D +VVG TVR EGY R R A+G+ V +A+V+ S LD + +FT + Sbjct 91 DAVVVGAETVRREGYRPPRAREAFVARRAAQGRPPVAAIAVVSASLDLDFSLPLFTEPLV 150 Query 139 APLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTL 198 LV+T D + +G+ G VD A +V+ LA RGL R+L+EGGP L Sbjct 151 PTLVVTGAQAPADRLAAARRAGAEVVLAGEGAG-VDPARVVAALAERGLTRLLSEGGPKL 209 Query 199 LGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRY 255 LG F VLDELCL++AP + G A RIV GP V + +D+G+L+T Y Sbjct 210 LGQFAAAGVLDELCLSLAPLIAAGDAERIVKGPELVEPERFTLFSILEDAGFLFTSY 266 >gi|271967965|ref|YP_003342161.1| pyrimidine reductase riboflavin biosynthesis-like protein [Streptosporangium roseum DSM 43021] gi|270511140|gb|ACZ89418.1| Pyrimidine reductase riboflavin biosynthesis- like protein [Streptosporangium roseum DSM 43021] Length=240 Score = 149 bits (377), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 103/238 (44%), Positives = 141/238 (60%), Gaps = 14/238 (5%) Query 25 DGELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVG 84 D +L Q Y YPD G +R N ++S DGG ++G SG ++G GDR +F +LR LADV+VVG Sbjct 11 DVDLAQAYAYPD-GPCVRVNMVASADGGTWLEGLSGGLSGGGDRRIFGVLRGLADVVVVG 69 Query 85 VGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAP---- 140 TVR EGY R R R+ G+ P +A+VTR RLD D+ E P Sbjct 70 AATVRTEGYGPARPRESWRPLRE--GRPAAPPVAVVTR--RLDLDLTGPLFAEAEPYART 125 Query 141 LVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLG 200 +V+T A + R+ AG A+VI D VD A V +L RGL R+L EGGP + Sbjct 126 IVITCEAAPAERREEAAGHADVIVAGRD---RVDLAAAVKELGERGLGRVLCEGGPKINA 182 Query 201 TFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVKT 258 ++DELCLT++P ++GG A RI+ GP LTR+R AHVL ++ G+L+TRY++ Sbjct 183 QLAAAGLVDELCLTLSPMLIGGDAARILDGPAS-LTRLRLAHVL-EEEGFLFTRYIRK 238 >gi|254393143|ref|ZP_05008301.1| diaminohydroxyphosphoribosylaminopyrimidine deaminase [Streptomyces clavuligerus ATCC 27064] gi|197706788|gb|EDY52600.1| diaminohydroxyphosphoribosylaminopyrimidine deaminase [Streptomyces clavuligerus ATCC 27064] Length=275 Score = 149 bits (375), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 104/236 (45%), Positives = 134/236 (57%), Gaps = 8/236 (3%) Query 27 ELPQLYDYPD---DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVV 83 EL Y YP DG WLRAN +SSLDG A +G S ++ D +F LR LAD +VV Sbjct 42 ELADAYAYPALPADGAWLRANMVSSLDGAAQHEGRSQPLSSDADMRIFGTLRALADAVVV 101 Query 84 GVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVL 143 G TVR E Y R R+A GQ P +A+V+ S LD + +FT + P ++ Sbjct 102 GAETVRREVYRPARAREAFAARRRAAGQGPAPAIAVVSASLALDFSLPLFTE-PLVPTLV 160 Query 144 TTTAVADDTRQRLAGLAEV-IACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTF 202 T A A R R A A V + +G+ G V+ A V LA +GLRR+LTEGGP LLG F Sbjct 161 LTGAAAPPERLREAERAGVRVLIAGEGRG-VEPATAVRVLAEQGLRRLLTEGGPRLLGHF 219 Query 203 VERDVLDELCLTIAPYVVGGLARRIVTGPGQ-VLTRMRCAHVLTDDSGYLYTRYVK 257 + VLDELCLT++P V G ++RI GP V R A VL +D G+L+TRY + Sbjct 220 MAAGVLDELCLTLSPTVTAGDSQRIAHGPAMAVPARFTLAGVLEED-GFLFTRYQR 274 >gi|291454887|ref|ZP_06594277.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Streptomyces albus J1074] gi|291357836|gb|EFE84738.1| 5-amino-6-(5-phosphoribosylamino)uracil reductase [Streptomyces albus J1074] Length=260 Score = 149 bits (375), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 105/238 (45%), Positives = 138/238 (58%), Gaps = 6/238 (2%) Query 24 TDGELPQLYDYPD-DGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIV 82 T EL Y YP+ DG WLRAN +S+LDG A +G S ++G D +F LR LAD +V Sbjct 17 TLAELADAYAYPETDGPWLRANMVSTLDGAAQHEGRSQPISGSADMRIFGTLRGLADAVV 76 Query 83 VGVGTVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLV 142 VG TVR EGY R + R A GQ+ P +A+V+ S LD D+ +F+ LV Sbjct 77 VGAETVRQEGYRPARAREAFARRRAAAGQAPAPAVAVVSASLALDFDLPLFSAPLTPTLV 136 Query 143 LT-TTAVADDTRQ-RLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLG 200 LT A AD R AG+ +IA +G VD A V+ LA GL R+LTEGGP LLG Sbjct 137 LTGAAAPADRVRAAEAAGVHVLIAGTG---AAVDPARAVAALAEHGLTRLLTEGGPRLLG 193 Query 201 TFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYTRYVKT 258 FV VLDELCLT++P + G A+RI GP L + + +++G+L+TRY +T Sbjct 194 QFVAAGVLDELCLTVSPMLTSGDAQRIAGGPSVALPKRFSPASVLEEAGFLFTRYRRT 251 >gi|117928582|ref|YP_873133.1| deaminase-reductase domain-containing protein [Acidothermus cellulolyticus 11B] gi|117649045|gb|ABK53147.1| bifunctional deaminase-reductase domain protein [Acidothermus cellulolyticus 11B] Length=249 Score = 148 bits (374), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 101/227 (45%), Positives = 137/227 (61%), Gaps = 8/227 (3%) Query 27 ELPQLYDYPDDGTWLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGVG 86 ++P Y YPD+ WLR N I+SLDG ATVDG +G + D+++ LLR LADV++VG Sbjct 18 DVPACYAYPDE-RWLRGNMIASLDGAATVDGRAGPLGNTADQWMLALLRALADVVLVGAA 76 Query 87 TVRIEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTT 146 T IEGY ++ ++ + R P AIV+R+ RLD +FT + PLV+T T Sbjct 77 TAEIEGYRPIQ---IREEFASLRRDRPSPVTAIVSRTLRLDVTGRLFT-SGARPLVITCT 132 Query 147 AVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVERD 206 + R +LA +A+++ +GD+ TVD V +LA RG RR+L EGGP LL D Sbjct 133 SAPARARHQLADVADIVV-AGDE--TVDLHHAVRELADRGHRRLLCEGGPRLLAALAAED 189 Query 207 VLDELCLTIAPYVVGGLARRIVTGPGQVLTRMRCAHVLTDDSGYLYT 253 +LDELCLTI+P +V G A RI+ G RMR AH+L D G LYT Sbjct 190 LLDELCLTISPLLVAGSAPRILDGTAITPRRMRLAHLLMDADGLLYT 236 >gi|328885914|emb|CCA59153.1| 5-amino-6-(5-phosphoribosylamino)uracilreductase [Streptomyces venezuelae ATCC 10712] Length=268 Score = 148 bits (374), Expect = 7e-34, Method: Compositional matrix adjust. Identities = 98/217 (46%), Positives = 123/217 (57%), Gaps = 3/217 (1%) Query 40 WLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGVGTVRIEGYSGVRMG 99 WLRAN +SSLDG DG S ++ D +F LR LADV+VVG TVR+EGY R Sbjct 51 WLRANMVSSLDGAGQHDGRSQPLSSEEDMRIFGTLRALADVVVVGAETVRLEGYRPARAR 110 Query 100 VVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMAPLVLTTTAVADDTRQRLAGL 159 R+A GQ P +A+V+ S LD + +FT + LVLT A + Sbjct 111 EAFAARREAAGQGPAPAIAVVSASLNLDFSLPLFTEPLVPTLVLTGAAAPAERVAAARAA 170 Query 160 AEVIACSGDDPGTVDEAVLVSQLAARGLRRILTEGGPTLLGTFVERDVLDELCLTIAPYV 219 + +GD G V+ A + LA RGLRR LTEGGP LLG FV D LDELCLT++P + Sbjct 171 GAEVLVAGDGAG-VEPARARAVLAERGLRRQLTEGGPRLLGQFVAADALDELCLTVSPTM 229 Query 220 VGGLARRIVTGPG-QVLTRMRCAHVLTDDSGYLYTRY 255 G A+RI GP V TR + A VL D G+L+TRY Sbjct 230 TSGAAQRIAGGPAVAVPTRFQVASVLEQD-GFLFTRY 265 Lambda K H 0.321 0.139 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 384134341080 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40