BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2675c

Length=250
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609812|ref|NP_217191.1|  hypothetical protein Rv2675c [Mycob...   516    1e-144
gi|289570849|ref|ZP_06451076.1|  conserved hypothetical protein [...   514    3e-144
gi|254365337|ref|ZP_04981382.1|  conserved hypothetical protein [...   512    2e-143
gi|308374659|ref|ZP_07436882.2|  hypothetical protein TMFG_03572 ...   463    9e-129
gi|254818552|ref|ZP_05223553.1|  hypothetical protein MintA_01441...   433    1e-119
gi|41408894|ref|NP_961730.1|  hypothetical protein MAP2796c [Myco...   432    3e-119
gi|342858454|ref|ZP_08715109.1|  hypothetical protein MCOL_06251 ...   429    2e-118
gi|254776010|ref|ZP_05217526.1|  hypothetical protein MaviaA2_152...   428    3e-118
gi|118463475|ref|YP_882748.1|  thiopurine S-methyltransferase (tp...   427    6e-118
gi|296171937|ref|ZP_06852982.1|  thiopurine S-methyltransferase (...   423    1e-116
gi|183982054|ref|YP_001850345.1|  methyltransferase [Mycobacteriu...   409    3e-112
gi|118618639|ref|YP_906971.1|  methyltransferase [Mycobacterium u...   406    2e-111
gi|289758803|ref|ZP_06518181.1|  predicted protein [Mycobacterium...   362    4e-98 
gi|240169730|ref|ZP_04748389.1|  hypothetical protein MkanA1_1048...   284    1e-74 
gi|240171251|ref|ZP_04749910.1|  hypothetical protein MkanA1_1820...   256    2e-66 
gi|333991216|ref|YP_004523830.1|  methyltransferase [Mycobacteriu...   250    1e-64 
gi|296168231|ref|ZP_06850204.1|  thiopurine S-methyltransferase f...   248    7e-64 
gi|333991597|ref|YP_004524211.1|  methyltransferase [Mycobacteriu...   245    5e-63 
gi|254551726|ref|ZP_05142173.1|  hypothetical protein Mtube_14927...   179    3e-43 
gi|169627345|ref|YP_001700994.1|  hypothetical protein MAB_0240 [...   173    2e-41 
gi|169627967|ref|YP_001701616.1|  hypothetical protein MAB_0868c ...   166    3e-39 
gi|302525631|ref|ZP_07277973.1|  predicted protein [Streptomyces ...   152    6e-35 
gi|291301387|ref|YP_003512665.1|  type 11 methyltransferase [Stac...   145    7e-33 
gi|300784405|ref|YP_003764696.1|  transferase [Amycolatopsis medi...   143    3e-32 
gi|268322269|emb|CBH32791.1|  putative dehydrogenase [Streptomyce...   136    3e-30 
gi|169627966|ref|YP_001701615.1|  putative transferase [Mycobacte...   135    5e-30 
gi|32140301|gb|AAP69591.1|  hypothetical protein [Streptomyces gr...   129    4e-28 
gi|340626391|ref|YP_004744843.1|  putative transferase [Mycobacte...   124    1e-26 
gi|15840835|ref|NP_335872.1|  hypothetical protein MT1421 [Mycoba...   124    1e-26 
gi|15608517|ref|NP_215893.1|  putative transferase [Mycobacterium...   124    1e-26 
gi|118472427|ref|YP_887357.1|  thiopurine S-methyltransferase (tp...   121    1e-25 
gi|302527461|ref|ZP_07279803.1|  conserved hypothetical protein [...   120    2e-25 
gi|126179070|ref|YP_001047035.1|  methyltransferase type 11 [Meth...   120    2e-25 
gi|333991061|ref|YP_004523675.1|  hypothetical protein JDM601_242...   119    5e-25 
gi|288916265|ref|ZP_06410644.1|  Methyltransferase type 11 [Frank...   119    6e-25 
gi|266631104|emb|CBH32104.1|  putative dehydrogenase and domain w...   118    1e-24 
gi|126180199|ref|YP_001048164.1|  methyltransferase type 11 [Meth...   116    3e-24 
gi|315445419|ref|YP_004078298.1|  methylase involved in ubiquinon...   116    3e-24 
gi|183982206|ref|YP_001850497.1|  NodS-like (sam)-dependent methy...   115    4e-24 
gi|325675063|ref|ZP_08154749.1|  thiopurine S-methyltransferase f...   115    7e-24 
gi|296170757|ref|ZP_06852329.1|  thiopurine S-methyltransferase f...   114    1e-23 
gi|312137777|ref|YP_004005113.1|  SAM dependent methyltransferase...   114    1e-23 
gi|240170754|ref|ZP_04749413.1|  hypothetical protein MkanA1_1568...   114    1e-23 
gi|120402886|ref|YP_952715.1|  type 11 methyltransferase [Mycobac...   113    2e-23 
gi|134098593|ref|YP_001104254.1|  methyltransferase type 11 [Sacc...   112    6e-23 
gi|119867652|ref|YP_937604.1|  type 11 methyltransferase [Mycobac...   111    8e-23 
gi|118468119|ref|YP_886428.1|  methyltransferase type 12 [Mycobac...   111    9e-23 
gi|108798553|ref|YP_638750.1|  type 11 methyltransferase [Mycobac...   111    9e-23 
gi|153003070|ref|YP_001377395.1|  type 12 methyltransferase [Anae...   111    1e-22 
gi|41406223|ref|NP_959059.1|  hypothetical protein MAP0125c [Myco...   111    1e-22 


>gi|15609812|ref|NP_217191.1| hypothetical protein Rv2675c [Mycobacterium tuberculosis H37Rv]
 gi|15842213|ref|NP_337250.1| hypothetical protein MT2749 [Mycobacterium tuberculosis CDC1551]
 gi|31793847|ref|NP_856340.1| hypothetical protein Mb2694c [Mycobacterium bovis AF2122/97]
 72 more sequence titles
 Length=250

 Score =  516 bits (1329),  Expect = 1e-144, Method: Compositional matrix adjust.
 Identities = 250/250 (100%), Positives = 250/250 (100%), Gaps = 0/250 (0%)

Query  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60
            MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG
Sbjct  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60

Query  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120
            PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV
Sbjct  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120

Query  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
            DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL
Sbjct  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180

Query  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240
            PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP
Sbjct  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240

Query  241  FWEVHATRVD  250
            FWEVHATRVD
Sbjct  241  FWEVHATRVD  250


>gi|289570849|ref|ZP_06451076.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
 gi|289544603|gb|EFD48251.1| conserved hypothetical protein [Mycobacterium tuberculosis T17]
Length=250

 Score =  514 bits (1325),  Expect = 3e-144, Method: Compositional matrix adjust.
 Identities = 249/250 (99%), Positives = 249/250 (99%), Gaps = 0/250 (0%)

Query  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60
            MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG
Sbjct  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60

Query  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120
            PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV
Sbjct  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120

Query  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
            DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEF EHNVNGFSMPRSLSEDDFRQVL
Sbjct  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFSEHNVNGFSMPRSLSEDDFRQVL  180

Query  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240
            PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP
Sbjct  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240

Query  241  FWEVHATRVD  250
            FWEVHATRVD
Sbjct  241  FWEVHATRVD  250


>gi|254365337|ref|ZP_04981382.1| conserved hypothetical protein [Mycobacterium tuberculosis str. 
Haarlem]
 gi|134150850|gb|EBA42895.1| conserved hypothetical protein [Mycobacterium tuberculosis str. 
Haarlem]
Length=250

 Score =  512 bits (1318),  Expect = 2e-143, Method: Compositional matrix adjust.
 Identities = 248/250 (99%), Positives = 248/250 (99%), Gaps = 0/250 (0%)

Query  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60
            MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG
Sbjct  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60

Query  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120
            PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV
Sbjct  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120

Query  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
            DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL
Sbjct  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180

Query  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240
            PVGGWEITYLGTTTYQVNLSVEALELMAARNPDM DQVRCVLERFRAIKPWLVGGRV AP
Sbjct  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMCDQVRCVLERFRAIKPWLVGGRVRAP  240

Query  241  FWEVHATRVD  250
            FWEVHATRVD
Sbjct  241  FWEVHATRVD  250


>gi|308374659|ref|ZP_07436882.2| hypothetical protein TMFG_03572 [Mycobacterium tuberculosis SUMu006]
 gi|308377091|ref|ZP_07441107.2| hypothetical protein TMHG_01874 [Mycobacterium tuberculosis SUMu008]
 gi|308341169|gb|EFP30020.1| hypothetical protein TMFG_03572 [Mycobacterium tuberculosis SUMu006]
 gi|308348924|gb|EFP37775.1| hypothetical protein TMHG_01874 [Mycobacterium tuberculosis SUMu008]
Length=225

 Score =  463 bits (1192),  Expect = 9e-129, Method: Compositional matrix adjust.
 Identities = 224/225 (99%), Positives = 225/225 (100%), Gaps = 0/225 (0%)

Query  26   LPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAI  85
            +PAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAI
Sbjct  1    MPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAI  60

Query  86   ERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRA  145
            ERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRA
Sbjct  61   ERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRA  120

Query  146  SKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALE  205
            SKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALE
Sbjct  121  SKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALE  180

Query  206  LMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATRVD  250
            LMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATRVD
Sbjct  181  LMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATRVD  225


>gi|254818552|ref|ZP_05223553.1| hypothetical protein MintA_01441 [Mycobacterium intracellulare 
ATCC 13950]
Length=250

 Score =  433 bits (1113),  Expect = 1e-119, Method: Compositional matrix adjust.
 Identities = 202/250 (81%), Positives = 222/250 (89%), Gaps = 0/250 (0%)

Query  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60
            MTA FDP DPTRFE+MYRDDR +HGLP ATPWDIGGPQPVVQQLVALGAI+GEVLDPGTG
Sbjct  1    MTAPFDPTDPTRFEQMYRDDRTSHGLPTATPWDIGGPQPVVQQLVALGAIKGEVLDPGTG  60

Query  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120
            PGHHAIYYA+KGY+ATGIDGS  AIERAR NA KAGVSVNF+V DAT LDG DG FDTVV
Sbjct  61   PGHHAIYYASKGYSATGIDGSAGAIERARANAEKAGVSVNFEVADATKLDGFDGHFDTVV  120

Query  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
            DCAFYHTFST P+L+R Y  ALRRA++PGARLYMFEFGEHN+NGF M RSLSE DFR VL
Sbjct  121  DCAFYHTFSTEPQLRRSYAEALRRATRPGARLYMFEFGEHNINGFKMLRSLSESDFRDVL  180

Query  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240
            P  GW+ITYLGTTTYQVN+S E++ELMAARNPDMAD+   +LERFRA++PWL G RV+AP
Sbjct  181  PDAGWDITYLGTTTYQVNISAESIELMAARNPDMADEAAKLLERFRAMEPWLDGSRVYAP  240

Query  241  FWEVHATRVD  250
            FWEVHATRVD
Sbjct  241  FWEVHATRVD  250


>gi|41408894|ref|NP_961730.1| hypothetical protein MAP2796c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41397253|gb|AAS05113.1| hypothetical protein MAP_2796c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336458825|gb|EGO37782.1| methyltransferase family protein [Mycobacterium avium subsp. 
paratuberculosis S397]
Length=250

 Score =  432 bits (1110),  Expect = 3e-119, Method: Compositional matrix adjust.
 Identities = 200/250 (80%), Positives = 223/250 (90%), Gaps = 0/250 (0%)

Query  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60
            MTA FDPADP RFEEMYRD R +HGLPAATPWDIGGPQPVV+QLVALGA++GEVLDPGTG
Sbjct  1    MTASFDPADPARFEEMYRDQRTSHGLPAATPWDIGGPQPVVRQLVALGAVKGEVLDPGTG  60

Query  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120
            PGHHAIYYA++G++ATGIDGS AAIERAR NARKAGVSVNF++ DAT LDG DGRFDTVV
Sbjct  61   PGHHAIYYASQGFSATGIDGSAAAIERARANARKAGVSVNFELADATKLDGFDGRFDTVV  120

Query  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
            DCAFYH F+T PEL+  Y RAL RA+KPGARLYMFEFGEH+VNGF M RSLSE+DFR VL
Sbjct  121  DCAFYHVFATEPELRSSYARALHRATKPGARLYMFEFGEHDVNGFKMMRSLSENDFRDVL  180

Query  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240
            P  GWEI+YLG TTYQVNLS E +++MAARNPDMAD+   +LERFRA++PWL GGRVHAP
Sbjct  181  PAAGWEISYLGPTTYQVNLSAETIQMMAARNPDMADEAAKLLERFRAMEPWLQGGRVHAP  240

Query  241  FWEVHATRVD  250
            FWEVHATRVD
Sbjct  241  FWEVHATRVD  250


>gi|342858454|ref|ZP_08715109.1| hypothetical protein MCOL_06251 [Mycobacterium colombiense CECT 
3035]
 gi|342134158|gb|EGT87338.1| hypothetical protein MCOL_06251 [Mycobacterium colombiense CECT 
3035]
Length=250

 Score =  429 bits (1102),  Expect = 2e-118, Method: Compositional matrix adjust.
 Identities = 201/250 (81%), Positives = 220/250 (88%), Gaps = 0/250 (0%)

Query  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60
            MT  FDP DPTRFEEMYRD R +HGLPAATPWDIGGPQPVVQQLVALGAI+GEVLDPGTG
Sbjct  1    MTTPFDPTDPTRFEEMYRDQRTSHGLPAATPWDIGGPQPVVQQLVALGAIKGEVLDPGTG  60

Query  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120
            PGHHAIYYA+KGY+ATGIDGS  AIERAR+NA+KAGVSVNF++ DAT L+G  GRFDTVV
Sbjct  61   PGHHAIYYASKGYSATGIDGSATAIERARENAQKAGVSVNFELADATKLEGFVGRFDTVV  120

Query  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
            DCAFYHTFST  EL+R YV AL RA+KPGARLYMFEFGEHNVNGF M RSLSE+DFR VL
Sbjct  121  DCAFYHTFSTEAELRRSYVDALHRATKPGARLYMFEFGEHNVNGFKMLRSLSENDFRDVL  180

Query  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240
            P GGWEITYLGTTTY+VN+S E++E MA RNPD+ADQ   +LERFR I+PWL G R HAP
Sbjct  181  PEGGWEITYLGTTTYRVNISAESIEAMAKRNPDIADQAEKLLERFRVIEPWLEGERAHAP  240

Query  241  FWEVHATRVD  250
            FWEVHATRVD
Sbjct  241  FWEVHATRVD  250


>gi|254776010|ref|ZP_05217526.1| hypothetical protein MaviaA2_15260 [Mycobacterium avium subsp. 
avium ATCC 25291]
Length=250

 Score =  428 bits (1101),  Expect = 3e-118, Method: Compositional matrix adjust.
 Identities = 199/250 (80%), Positives = 221/250 (89%), Gaps = 0/250 (0%)

Query  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60
            MTA FDPADP RFEEMYRD R +HGLPAATPWDIGGPQPVV+QLVALGAI+GEVLDPGTG
Sbjct  1    MTASFDPADPARFEEMYRDQRTSHGLPAATPWDIGGPQPVVRQLVALGAIKGEVLDPGTG  60

Query  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120
            PGHHAIYYA++G++ATGIDGS AAIERAR NA KAGVSVNF++ DAT LDG DGRFDTVV
Sbjct  61   PGHHAIYYASQGFSATGIDGSAAAIERARANAHKAGVSVNFELADATKLDGFDGRFDTVV  120

Query  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
            DCAFYH F+  PEL+  Y RAL RA+KPGARLYMFEFGEH+VNGF M RSLSE+DFR VL
Sbjct  121  DCAFYHVFAAEPELRSSYARALHRATKPGARLYMFEFGEHDVNGFKMMRSLSENDFRDVL  180

Query  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240
            P  GWEI+YLG TTYQVNLS E +++MAARNPDMAD+   +LERFRA++PWL GGRVHAP
Sbjct  181  PAAGWEISYLGPTTYQVNLSAETIQMMAARNPDMADEAAKLLERFRAMEPWLQGGRVHAP  240

Query  241  FWEVHATRVD  250
            FWEVHATRVD
Sbjct  241  FWEVHATRVD  250


>gi|118463475|ref|YP_882748.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium 104]
 gi|118164762|gb|ABK65659.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
avium 104]
Length=250

 Score =  427 bits (1099),  Expect = 6e-118, Method: Compositional matrix adjust.
 Identities = 198/250 (80%), Positives = 221/250 (89%), Gaps = 0/250 (0%)

Query  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60
            MTA FDPADP RFEEMYRD R +HGLPAATPWDIGGPQPVV+QLVALGA++GEVLDPGTG
Sbjct  1    MTASFDPADPARFEEMYRDQRTSHGLPAATPWDIGGPQPVVRQLVALGAVKGEVLDPGTG  60

Query  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120
            PGHHAIYYA++G++ATGIDGS AAIERAR NAR AGVSVNF++ DAT LDG DGRFDTVV
Sbjct  61   PGHHAIYYASQGFSATGIDGSAAAIERARANARTAGVSVNFELADATKLDGFDGRFDTVV  120

Query  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
            DCAFYH F+T PEL+  Y RAL RA+KPGARLYMFEFGEH+VNGF M RSLSE+DFR VL
Sbjct  121  DCAFYHVFATEPELRSSYARALHRATKPGARLYMFEFGEHDVNGFKMMRSLSENDFRDVL  180

Query  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240
            P  GWEI+YLG TTYQVNLS E +++MAARNPDMAD+   +LERFRA++PWL  GRVHAP
Sbjct  181  PAAGWEISYLGPTTYQVNLSAETIQMMAARNPDMADEAAKLLERFRAMEPWLQAGRVHAP  240

Query  241  FWEVHATRVD  250
            FWEVHATRVD
Sbjct  241  FWEVHATRVD  250


>gi|296171937|ref|ZP_06852982.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295893870|gb|EFG73642.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=249

 Score =  423 bits (1087),  Expect = 1e-116, Method: Compositional matrix adjust.
 Identities = 198/245 (81%), Positives = 223/245 (92%), Gaps = 0/245 (0%)

Query  6    DPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHA  65
            D  DP RFEEMYRD+R ++GLP ATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHA
Sbjct  5    DVTDPARFEEMYRDERTSNGLPTATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHA  64

Query  66   IYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFY  125
            IYYAAKGY+ATGIDGS  A+ERAR+NAR+AGVSVNF++ DAT L+GL+GRFDTVVDCAFY
Sbjct  65   IYYAAKGYSATGIDGSPGALERARENARRAGVSVNFELADATRLEGLEGRFDTVVDCAFY  124

Query  126  HTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGW  185
            HTFST PELQR YV+ALRRA+KPGARLYMFEFG H+VNGF M RSLSE+DFR VLP+GGW
Sbjct  125  HTFSTEPELQRSYVQALRRATKPGARLYMFEFGAHDVNGFKMMRSLSENDFRDVLPLGGW  184

Query  186  EITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVH  245
            EI+YLG TTY VN+SVE +E+MAARNPD A+Q + +LERFRA++PWL GGRVHAPFWEVH
Sbjct  185  EISYLGPTTYLVNISVEQIEMMAARNPDAAEQAQELLERFRAMEPWLEGGRVHAPFWEVH  244

Query  246  ATRVD  250
            ATRVD
Sbjct  245  ATRVD  249


>gi|183982054|ref|YP_001850345.1| methyltransferase [Mycobacterium marinum M]
 gi|183175380|gb|ACC40490.1| methyltransferase [Mycobacterium marinum M]
Length=249

 Score =  409 bits (1050),  Expect = 3e-112, Method: Compositional matrix adjust.
 Identities = 194/250 (78%), Positives = 218/250 (88%), Gaps = 1/250 (0%)

Query  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60
            MTA  DP DPTRFEEMYRD RVAHGLPAATPWDIGGPQPVV+QLVALGA++GEVLDPGTG
Sbjct  1    MTAP-DPTDPTRFEEMYRDQRVAHGLPAATPWDIGGPQPVVEQLVALGAVKGEVLDPGTG  59

Query  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120
            PGHHAIYYA+KGY+ATGIDGS  AIERARDNA KAGVSVNFQV DAT L+GLD RFDTVV
Sbjct  60   PGHHAIYYASKGYSATGIDGSATAIERARDNAAKAGVSVNFQVADATRLEGLDNRFDTVV  119

Query  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
            DCAFYHTF TAPELQR YVRAL RA+KPGARLYM+EFG H VNG +  RSL E++FR++L
Sbjct  120  DCAFYHTFGTAPELQRSYVRALWRATKPGARLYMYEFGAHQVNGLTAIRSLPEENFREML  179

Query  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240
            P+GGWEITYLG TTY+  +S+E LE MAARNP++ADQV  ++ERF+ I+PWL  G  H P
Sbjct  180  PLGGWEITYLGPTTYRTTVSMETLETMAARNPEVADQVGPLVERFKTIQPWLTDGIAHVP  239

Query  241  FWEVHATRVD  250
            FWEVHATR+D
Sbjct  240  FWEVHATRLD  249


>gi|118618639|ref|YP_906971.1| methyltransferase [Mycobacterium ulcerans Agy99]
 gi|118570749|gb|ABL05500.1| methyltransferase [Mycobacterium ulcerans Agy99]
Length=249

 Score =  406 bits (1043),  Expect = 2e-111, Method: Compositional matrix adjust.
 Identities = 193/250 (78%), Positives = 217/250 (87%), Gaps = 1/250 (0%)

Query  1    MTAQFDPADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTG  60
            MTA  DP DPTRFEEMYRD RVAHGLPAATPWDIGGPQPVV+QLVALGA++GEVLDPGTG
Sbjct  1    MTAP-DPTDPTRFEEMYRDQRVAHGLPAATPWDIGGPQPVVEQLVALGAVKGEVLDPGTG  59

Query  61   PGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVV  120
            PGHHAIYYA+KGY+ATGIDGS  AIERARDNA KAGVSVNFQV DAT L+GLD RFDTVV
Sbjct  60   PGHHAIYYASKGYSATGIDGSATAIERARDNAAKAGVSVNFQVADATRLEGLDNRFDTVV  119

Query  121  DCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
            DCAFYHTF TAPELQR YV+AL RA+KPGARLYM+EFG H VNG +  RSL E++FR++L
Sbjct  120  DCAFYHTFGTAPELQRSYVQALWRATKPGARLYMYEFGAHQVNGLTAIRSLPEENFREML  179

Query  181  PVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAP  240
            P+GGWEITYLG TTY+  +S+E LE MAARNP++ADQV  ++ERF+ I+PWL  G  H P
Sbjct  180  PLGGWEITYLGPTTYRTTVSMETLETMAARNPEVADQVGPLVERFKTIQPWLTDGIAHVP  239

Query  241  FWEVHATRVD  250
            FWEVHATR D
Sbjct  240  FWEVHATRPD  249


>gi|289758803|ref|ZP_06518181.1| predicted protein [Mycobacterium tuberculosis T85]
 gi|289714367|gb|EFD78379.1| predicted protein [Mycobacterium tuberculosis T85]
Length=232

 Score =  362 bits (928),  Expect = 4e-98, Method: Compositional matrix adjust.
 Identities = 180/201 (90%), Positives = 182/201 (91%), Gaps = 2/201 (0%)

Query  50   IRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTL  109
            +RG    PG  PG        +     GIDGSVAAIERARDNARKAGVSVNFQVGDATTL
Sbjct  34   VRGSTRAPG--PGTTRSTTPPRDMRPPGIDGSVAAIERARDNARKAGVSVNFQVGDATTL  91

Query  110  DGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPR  169
            DGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPR
Sbjct  92   DGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPR  151

Query  170  SLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIK  229
            SLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIK
Sbjct  152  SLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIK  211

Query  230  PWLVGGRVHAPFWEVHATRVD  250
            PWLVGGRVHAPFWEVHATRVD
Sbjct  212  PWLVGGRVHAPFWEVHATRVD  232


>gi|240169730|ref|ZP_04748389.1| hypothetical protein MkanA1_10482 [Mycobacterium kansasii ATCC 
12478]
Length=160

 Score =  284 bits (726),  Expect = 1e-74, Method: Compositional matrix adjust.
 Identities = 130/157 (83%), Positives = 148/157 (95%), Gaps = 0/157 (0%)

Query  94   KAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKPGARLY  153
            K GVSV+F+V DAT L+GLDGRFDTVVDCAFYHTFSTAPELQ+ YV+AL RA+KPGARLY
Sbjct  4    KVGVSVDFRVADATKLEGLDGRFDTVVDCAFYHTFSTAPELQKSYVQALHRATKPGARLY  63

Query  154  MFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALELMAARNPD  213
            MFEFGEH+VNGF+M RSLS+DDFRQVLPVGGWEITY+G TTYQ+NLSVE +E+MAARNPD
Sbjct  64   MFEFGEHDVNGFTMERSLSQDDFRQVLPVGGWEITYMGPTTYQINLSVEVIEMMAARNPD  123

Query  214  MADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATRVD  250
            MAD+VR +LERFRA++PWLVGGRVHAPFWEVHATR+D
Sbjct  124  MADEVRPMLERFRAMEPWLVGGRVHAPFWEVHATRLD  160


>gi|240171251|ref|ZP_04749910.1| hypothetical protein MkanA1_18201 [Mycobacterium kansasii ATCC 
12478]
Length=247

 Score =  256 bits (653),  Expect = 2e-66, Method: Compositional matrix adjust.
 Identities = 130/242 (54%), Positives = 166/242 (69%), Gaps = 8/242 (3%)

Query  13   FEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKG  72
            FE +Y D  +  GL    PWDIGGPQPVV+QLVA G IRGEVLDPGTGPG+HAI+YA++G
Sbjct  10   FEPLYGDPELNDGL---IPWDIGGPQPVVEQLVAFGGIRGEVLDPGTGPGYHAIHYASQG  66

Query  73   YAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAP  132
            ++ TG+DGS +AIERAR NA +AGV+V+F+V DAT LDG +GRFDTVVD AFYH F    
Sbjct  67   FSVTGVDGSPSAIERARRNADRAGVTVDFRVADATRLDGFEGRFDTVVDSAFYHVFLGDE  126

Query  133  ELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGT  192
              Q  Y +AL RA++PGARLYMFEF  HNVNG      +  D+F +VL  GGW + YLG 
Sbjct  127  ATQTRYTQALHRATRPGARLYMFEFSPHNVNGIQWA-GIPADNFDRVLGAGGWRVDYLGA  185

Query  193  TTYQVNLSVEALELM----AARNPDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATR  248
            TTYQ        + M    + R  +M +++R ++++   ++P L   RVH P W V ATR
Sbjct  186  TTYQARFLPRTFDAMTKVVSERQDEMLERMRPLVQQLNVLQPLLQDHRVHIPVWAVVATR  245

Query  249  VD  250
            +D
Sbjct  246  LD  247


>gi|333991216|ref|YP_004523830.1| methyltransferase [Mycobacterium sp. JDM601]
 gi|333487184|gb|AEF36576.1| methyltransferase [Mycobacterium sp. JDM601]
Length=242

 Score =  250 bits (639),  Expect = 1e-64, Method: Compositional matrix adjust.
 Identities = 131/245 (54%), Positives = 169/245 (69%), Gaps = 7/245 (2%)

Query  7    PADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAI  66
            PADPT F+ MYRD++   G     PWDIGGPQP VQ+LVA GA+RGEVLDPGTGPGHHAI
Sbjct  2    PADPT-FDAMYRDEQTDAG---TVPWDIGGPQPAVQELVAHGALRGEVLDPGTGPGHHAI  57

Query  67   YYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYH  126
            ++AA+GY ATG+D S AA+E AR NA +AGV+V+F+V DAT L   +GRFDTVVD AFYH
Sbjct  58   HFAARGYTATGVDASPAAVEHARRNAERAGVTVDFRVADATRLADFEGRFDTVVDSAFYH  117

Query  127  TFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWE  186
             F+   ELQ  Y+RAL  A+ PGARL+MFE G HN+NG      L  D+F ++L   GW 
Sbjct  118  VFAHDEELQARYIRALHFATAPGARLFMFELGRHNLNGLQF-DGLPADNFGRLLDENGWR  176

Query  187  ITYLGTTTYQVNLSVEALELMAARNPD--MADQVRCVLERFRAIKPWLVGGRVHAPFWEV  244
            + YLGT+TY       AL  ++  + D  +A Q++ + ++  A++P L   RVH P W V
Sbjct  177  LDYLGTSTYVGAFGPRALAFLSRLDSDDGVAPQMKGLPDQLGALEPPLDNHRVHLPMWSV  236

Query  245  HATRV  249
             A+R+
Sbjct  237  VASRL  241


>gi|296168231|ref|ZP_06850204.1| thiopurine S-methyltransferase family protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295896803|gb|EFG76434.1| thiopurine S-methyltransferase family protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=246

 Score =  248 bits (633),  Expect = 7e-64, Method: Compositional matrix adjust.
 Identities = 127/224 (57%), Positives = 151/224 (68%), Gaps = 5/224 (2%)

Query  31   PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERARD  90
            PWDIGGPQP VQQLVA G IRGEVLDPGTGPG+HAI++AA+GY+ATGID S +AIERA+ 
Sbjct  24   PWDIGGPQPAVQQLVAYGGIRGEVLDPGTGPGYHAIHFAAQGYSATGIDDSPSAIERAKR  83

Query  91   NARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKPGA  150
            NA +AGV V+FQV DAT L+G DGRFDTVVD AFYH F     +Q  Y +AL RA++PGA
Sbjct  84   NAERAGVEVDFQVADATRLEGFDGRFDTVVDSAFYHVFLNDGVVQTRYAQALHRATRPGA  143

Query  151  RLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALELMAAR  210
            RLYMFEF  HNVNG     ++  D+F +V    GW I YLG TTYQ     E  + M   
Sbjct  144  RLYMFEFSPHNVNGLQWT-AIPADNFERVFGANGWRIDYLGGTTYQARFLKETFDAMKTF  202

Query  211  NPDMADQV----RCVLERFRAIKPWLVGGRVHAPFWEVHATRVD  250
              D   ++    R ++ R   I P L   RVH P W V ATR+D
Sbjct  203  ASDQQGEILQRMRPLVHRLGVIDPLLEDHRVHLPVWSVVATRLD  246


>gi|333991597|ref|YP_004524211.1| methyltransferase [Mycobacterium sp. JDM601]
 gi|333487565|gb|AEF36957.1| methyltransferase [Mycobacterium sp. JDM601]
Length=241

 Score =  245 bits (625),  Expect = 5e-63, Method: Compositional matrix adjust.
 Identities = 135/242 (56%), Positives = 159/242 (66%), Gaps = 8/242 (3%)

Query  16   MYRDDRVAHGLPAA--TPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGY  73
            M  D   A  +P+    PWDIG PQPVVQQLVA GA+RGEVLDPGTGPGHHAI+YA++GY
Sbjct  1    MSSDAEFAGAVPSGPPEPWDIGRPQPVVQQLVAYGALRGEVLDPGTGPGHHAIHYASQGY  60

Query  74   AATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPE  133
              TGID + AAI  A+ NA KAGV+VNFQV DA  L G DGRFDTVVD AFYH F    E
Sbjct  61   PTTGIDVAPAAIAGAQRNAAKAGVTVNFQVADAVELAGFDGRFDTVVDSAFYHVFQDDEE  120

Query  134  LQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTT  193
             Q  Y R+L RA+KP ARLYMFE G HNVNG+ +   LS + F  +L   GW I ++G T
Sbjct  121  TQLRYARSLHRATKPQARLYMFEAGRHNVNGWQL-DGLSPERFGPLLAEAGWRIDHIGPT  179

Query  194  TYQ----VNLSVEALELMAARN-PDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATR  248
            TYQ     N   E + +M A    D+ D VR + ERF  ++P L    VH PFW V ATR
Sbjct  180  TYQGTFDPNSFTEMITVMEALGREDLLDGVRALAERFAYLQPLLEDNVVHMPFWAVTATR  239

Query  249  VD  250
            +D
Sbjct  240  LD  241


>gi|254551726|ref|ZP_05142173.1| hypothetical protein Mtube_14927 [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
Length=180

 Score =  179 bits (454),  Expect = 3e-43, Method: Compositional matrix adjust.
 Identities = 87/88 (99%), Positives = 88/88 (100%), Gaps = 0/88 (0%)

Query  19   DDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGI  78
            DDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGI
Sbjct  1    DDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGI  60

Query  79   DGSVAAIERARDNARKAGVSVNFQVGDA  106
            DGSVAAIERARDNARKAGVSVNFQVGD+
Sbjct  61   DGSVAAIERARDNARKAGVSVNFQVGDS  88


>gi|169627345|ref|YP_001700994.1| hypothetical protein MAB_0240 [Mycobacterium abscessus ATCC 19977]
 gi|169239312|emb|CAM60340.1| Conserved hypothetical protein (thiopurine S-methyltransferase?) 
[Mycobacterium abscessus]
Length=222

 Score =  173 bits (438),  Expect = 2e-41, Method: Compositional matrix adjust.
 Identities = 102/220 (47%), Positives = 129/220 (59%), Gaps = 21/220 (9%)

Query  29   ATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERA  88
            A PWDIGGPQPV++QLVALGA+RGEVLDPG G G HAI YA  G + TG+D +  AI RA
Sbjct  18   AAPWDIGGPQPVIRQLVALGAVRGEVLDPGCGTGWHAIEYARAGCSVTGVDLAPTAIARA  77

Query  89   RDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKP  148
            R+N R AGV   F +GDATTLD  + RFDTVVD        +A    R Y+R+L RA KP
Sbjct  78   RNNTRTAGVEAQFVLGDATTLD-YEARFDTVVDSKLLDNLDSAEARGR-YLRSLYRAMKP  135

Query  149  GARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQVNLSVEALELMA  208
              RL+++ F + +VNGF     L   D+   L   G+ ITYLG TTY+  LS+ +   + 
Sbjct  136  QGRLFLYGFSDGHVNGFHN-HELDGIDYEMALTAAGFTITYLGETTYR--LSIPSYRRIC  192

Query  209  ARNPDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATR  248
               PD              + P    G++H P  E+HA R
Sbjct  193  TDCPDQ-------------VPP---DGQIHIPMIEIHAVR  216


>gi|169627967|ref|YP_001701616.1| hypothetical protein MAB_0868c [Mycobacterium abscessus ATCC 
19977]
 gi|169239934|emb|CAM60962.1| Conserved hypothetical protein [Mycobacterium abscessus]
Length=262

 Score =  166 bits (420),  Expect = 3e-39, Method: Compositional matrix adjust.
 Identities = 105/267 (40%), Positives = 150/267 (57%), Gaps = 25/267 (9%)

Query  1    MTAQFDPAD-PTR--FEEMYRDDRVAHGLPAA-TPWDIGGPQPVVQQLVALGAIRGEVLD  56
            MTA   P D P++  FE +Y    +  G PAA  PWDI   QP +++L A GA+RG +LD
Sbjct  1    MTASTQPPDVPSQETFEAVYNGKPMFEGAPAAGVPWDIRDAQPRIKELAAYGALRGAILD  60

Query  57   PGTGPGHHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRF  116
             G G G ++IY   +G + TG+D S +AIE+A+  A  AGV+V+  V DAT LDG D +F
Sbjct  61   IGCGLGENSIYLTQQGLSVTGLDFSPSAIEQAKQRAAAAGVTVDLHVADATKLDGWDAQF  120

Query  117  DTVVDCAFYHTFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSE-DD  175
            DTV+D A YH F    E  R Y  AL RA++PGAR ++  FG+ +VNG +MP  + + D+
Sbjct  121  DTVIDSAVYHCFDH--EGHRQYASALHRATRPGARWFIACFGDGSVNGITMPFGVQDPDE  178

Query  176  FRQVLPVGGWEITYLGTTTYQ------VNLSVEAL--ELMAA------RNPDMADQVRCV  221
             + VL    W I Y G TTY       V  ++  +  E M A      + P +A+Q +  
Sbjct  179  IKSVLSEARWNIQYFGRTTYLGSRAAFVGAALAGIDPEQMPADMRERYQRPGVAEQAQQT  238

Query  222  LERFRAIKPWLVGGRVHAPFWEVHATR  248
             ER + +   +    +H PF+ + A R
Sbjct  239  FERLQQLDDDM----IHMPFFNIVAER  261


>gi|302525631|ref|ZP_07277973.1| predicted protein [Streptomyces sp. AA4]
 gi|302434526|gb|EFL06342.1| predicted protein [Streptomyces sp. AA4]
Length=234

 Score =  152 bits (383),  Expect = 6e-35, Method: Compositional matrix adjust.
 Identities = 94/236 (40%), Positives = 125/236 (53%), Gaps = 10/236 (4%)

Query  13   FEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKG  72
            FEEMY+       +    PWDI GPQP V  L A G   GEVLD G G G +A+Y A++G
Sbjct  8    FEEMYQGKTP---IGEKIPWDIAGPQPAVVALEADGGFHGEVLDIGCGLGENAMYLASRG  64

Query  73   YAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAP  132
            +  TG+DG+  A+ RAR+ A K G+ V F   DAT L+G +GRFD V+D A YH      
Sbjct  65   HRVTGLDGAPTALARARETAAKRGLDVTFAQADATRLEGYEGRFDAVLDSALYHCLDE--  122

Query  133  ELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGT  192
            E +  YV AL RA+KPGA+L +F F +     F +P  ++E + R+ +   GW IT L  
Sbjct  123  EERHAYVAALGRATKPGAQLNIFCFSDAVPENFPIPYRITEQNLRETVG-NGWTITALEP  181

Query  193  TTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATR  248
              Y   +S E L    A   +        L+     +     GRV AP W + ATR
Sbjct  182  AVYTTAMSREGLIAAVAAVSEGEPPDPTALDTLDVDEQ----GRVLAPVWRLAATR  233


>gi|291301387|ref|YP_003512665.1| type 11 methyltransferase [Stackebrandtia nassauensis DSM 44728]
 gi|290570607|gb|ADD43572.1| Methyltransferase type 11 [Stackebrandtia nassauensis DSM 44728]
Length=243

 Score =  145 bits (365),  Expect = 7e-33, Method: Compositional matrix adjust.
 Identities = 92/242 (39%), Positives = 124/242 (52%), Gaps = 18/242 (7%)

Query  13   FEEMYRDDRVAHGLPA---ATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYA  69
            FE +YR   +  GLP    +TPWDIG PQPV+  + A G +RG VLD G G G +A++ A
Sbjct  15   FESVYRGGPLIDGLPEGAPSTPWDIGEPQPVLVAVEAAGQVRGTVLDVGCGLGENALFLA  74

Query  70   AKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFS  129
             +GY  TG+D S  A+E+AR  A   GV V+F VGDAT L GLD RFDTV+D A +H   
Sbjct  75   GRGYRVTGVDISPTALEQARQRAADKGVEVDFVVGDATRLAGLDARFDTVIDSALFHCLK  134

Query  130  TAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITY  189
              PEL+  Y+ AL R   PG  ++MF   +    G  +P  ++E+  R      GW I  
Sbjct  135  --PELRNDYLAALHRVCVPGGTVHMFCGTDSGPAGMPVPFPINEEVLRDAFGT-GWRIDE  191

Query  190  LGTTTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLV--GGRVHAPFWEVHAT  247
            L    Y      E          D A  +  +      +    V   GR+  P W++ AT
Sbjct  192  LRLDRYTAVFGRE----------DFAGLLTSMGAPTTGVDELEVDDAGRLRLPVWKLAAT  241

Query  248  RV  249
            R+
Sbjct  242  RL  243


>gi|300784405|ref|YP_003764696.1| transferase [Amycolatopsis mediterranei U32]
 gi|299793919|gb|ADJ44294.1| putative transferase [Amycolatopsis mediterranei U32]
 gi|340525826|gb|AEK41031.1| transferase [Amycolatopsis mediterranei S699]
Length=231

 Score =  143 bits (360),  Expect = 3e-32, Method: Compositional matrix adjust.
 Identities = 90/242 (38%), Positives = 127/242 (53%), Gaps = 25/242 (10%)

Query  13   FEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKG  72
            FEE+Y+    A  +    PWD+G PQP V  L   G   GEVLD G G G ++ + A++G
Sbjct  8    FEELYQG---ATPMGRKMPWDLGAPQPAVVALADAGEFTGEVLDIGCGLGDNSAFLASRG  64

Query  73   YAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAP  132
               TG+DG+ +A+E+AR  A + G+ + F V DAT L+G +GRFDTV+D A YH    A 
Sbjct  65   LRVTGLDGAPSALEQARSRAAEKGLDIEFAVADATKLEGYEGRFDTVLDSALYHCL--AE  122

Query  133  ELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGT  192
            + +  Y+ AL RA++PGA L++F F E   + F  P  +SE + R+ +    W I  L  
Sbjct  123  DERHAYLAALTRATRPGATLHLFCFSEEVPDAFPAPYLISEANLRETVG-KDWTIERLEP  181

Query  193  TTYQVNLSVEALELMAARNPDMADQVRCVLERFRAIKPWLVG------GRVHAPFWEVHA  246
              Y  +++ E L             VR VL    A    L G      GRV  P W++ A
Sbjct  182  AVYTTSMTAEELR----------QSVRVVL---GAEPGGLTGMDTDADGRVLVPVWQLKA  228

Query  247  TR  248
             R
Sbjct  229  VR  230


>gi|268322269|emb|CBH32791.1| putative dehydrogenase [Streptomyces sp. C23201NS3]
Length=776

 Score =  136 bits (343),  Expect = 3e-30, Method: Compositional matrix adjust.
 Identities = 94/244 (39%), Positives = 128/244 (53%), Gaps = 22/244 (9%)

Query  13   FEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKG  72
            F  MY+ D+ A   P   PWDIG PQP +      G I G+VLD G G G +A + A++G
Sbjct  549  FVSMYQGDQDA---PPVQPWDIGRPQPALVDAHKAGLITGDVLDVGCGLGDNAAFLASQG  605

Query  73   YAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAP  132
            +  T +D S  A++ A   A   GV V F V DAT L G DGRFDTVVD A YH+ +   
Sbjct  606  HRVTAVDVSQIAVDEASARASAKGVEVEFAVTDATRLTGFDGRFDTVVDSACYHSLAEDD  665

Query  133  ELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGG-WEITYLG  191
             ++  Y+ AL RA++PGARL++F F E     F  P   S    R+V  VGG W++  + 
Sbjct  666  RVR--YLEALHRAARPGARLHIFSFAEELPAPFPGPHRHSARSLREV--VGGVWDVVSVE  721

Query  192  TTTYQVNL-SVEALELMAARNPDM---ADQVRCV-LERFRAIKPWLVGGRVHAPFWEVHA  246
              TY  +L + + +E+  A  PD    AD +  + L+ F         G+   P W V A
Sbjct  722  EATYASSLGAADVVEMTRAEYPDRDVDADSLPGLELDEF---------GKATMPVWHVVA  772

Query  247  TRVD  250
             R D
Sbjct  773  VRRD  776


>gi|169627966|ref|YP_001701615.1| putative transferase [Mycobacterium abscessus ATCC 19977]
 gi|169239933|emb|CAM60961.1| Putative transferase [Mycobacterium abscessus]
Length=235

 Score =  135 bits (340),  Expect = 5e-30, Method: Compositional matrix adjust.
 Identities = 83/184 (46%), Positives = 113/184 (62%), Gaps = 6/184 (3%)

Query  13   FEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKG  72
            FE++YRD  +  G P   PWD    +P +++L  LGAIRG+VLD G G G +AIY A +G
Sbjct  9    FEDLYRD-SLHEGGPI-VPWDSKDAKPRIKELALLGAIRGDVLDIGCGLGDNAIYLAQQG  66

Query  73   YAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAP  132
            +  TG+D + +AIE+A+  A  AGV+V+FQV DATTLDG D RFDTV+D   YH F    
Sbjct  67   FNVTGLDFAPSAIEQAKGRAAAAGVAVDFQVADATTLDGWDARFDTVIDSGVYHCFDA--  124

Query  133  ELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSE--DDFRQVLPVGGWEITYL  190
            E    Y  AL RA++PGAR Y++ F +  V+G   P    +  ++  QVL   GW +  +
Sbjct  125  EGHTEYASALHRATRPGARWYIWCFAQGAVHGVPTPFQNGQRAEEIEQVLTTSGWSVLQI  184

Query  191  GTTT  194
              TT
Sbjct  185  NPTT  188


>gi|32140301|gb|AAP69591.1| hypothetical protein [Streptomyces griseoflavus]
Length=247

 Score =  129 bits (324),  Expect = 4e-28, Method: Compositional matrix adjust.
 Identities = 76/195 (39%), Positives = 107/195 (55%), Gaps = 6/195 (3%)

Query  13   FEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKG  72
            FE++Y+D   +  L    PW+IGGPQP V+ +   G  RG VLD G G G +A+Y A++G
Sbjct  11   FEKLYQDGEKSGPL---MPWNIGGPQPAVRAICDRGGFRGHVLDLGCGLGDNALYLASRG  67

Query  73   YAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAP  132
               + +D S  A++  RD AR  GVSV+FQV DA  L     R+D V+D AF+HT     
Sbjct  68   LRVSAVDISEVAVQCGRDKARDHGVSVDFQVTDAFRLAESGVRYDAVLDSAFFHTLPQE-  126

Query  133  ELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGT  192
            E+ R Y   LR   K GA L++F F +     +  PR +SE + R+      W+I  +  
Sbjct  127  EVPR-YTELLRTLCKEGAELHLFTFSKELTPDYPGPRRISEPELREAFG-ADWDIKVIEA  184

Query  193  TTYQVNLSVEALELM  207
            T Y  +L  EA+  M
Sbjct  185  TRYHSSLPPEAVAQM  199


>gi|340626391|ref|YP_004744843.1| putative transferase [Mycobacterium canettii CIPT 140010059]
 gi|340004581|emb|CCC43725.1| putative transferase [Mycobacterium canettii CIPT 140010059]
Length=212

 Score =  124 bits (312),  Expect = 1e-26, Method: Compositional matrix adjust.
 Identities = 77/197 (40%), Positives = 102/197 (52%), Gaps = 5/197 (2%)

Query  13   FEEMYRDDRVAHGLPAAT--PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA  70
            F+ +YR +    GLP  T  PWD   P+  V      G + G+VLD G G G +AIY A 
Sbjct  6    FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR  65

Query  71   KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST  130
             GY  TG+D S  A+  A+  A  AGV V F VGDAT L G  G FDTV+DC  +H    
Sbjct  66   NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD  125

Query  131  APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRS-LSEDDFRQVLPVGGWEITY  189
              + +R Y  ++ RA++PGA L +  F +        PRS +SE   R VL   GW+I  
Sbjct  126  --DGKRSYAASVHRATRPGATLLLSCFSDAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES  183

Query  190  LGTTTYQVNLSVEALEL  206
            L   T +  L    +E+
Sbjct  184  LEPATVRRELDGTEVEM  200


>gi|15840835|ref|NP_335872.1| hypothetical protein MT1421 [Mycobacterium tuberculosis CDC1551]
 gi|308231825|ref|ZP_07663943.1| transferase [Mycobacterium tuberculosis SUMu001]
 gi|308369784|ref|ZP_07666806.1| transferase [Mycobacterium tuberculosis SUMu002]
 19 more sequence titles
 Length=226

 Score =  124 bits (311),  Expect = 1e-26, Method: Compositional matrix adjust.
 Identities = 77/197 (40%), Positives = 101/197 (52%), Gaps = 5/197 (2%)

Query  13   FEEMYRDDRVAHGLPAAT--PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA  70
            F+ +YR +    GLP  T  PWD   P+  V      G + G+VLD G G G +AIY A 
Sbjct  20   FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR  79

Query  71   KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST  130
             GY  TG+D S  A+  A+  A  AGV V F VGDAT L G  G FDTV+DC  +H    
Sbjct  80   NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD  139

Query  131  APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRS-LSEDDFRQVLPVGGWEITY  189
              + +R Y  ++ RA++PGA L +  F          PRS +SE   R VL   GW+I  
Sbjct  140  --DGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES  197

Query  190  LGTTTYQVNLSVEALEL  206
            L   T +  L    +E+
Sbjct  198  LEPATVRRELDGTEVEM  214


>gi|15608517|ref|NP_215893.1| putative transferase [Mycobacterium tuberculosis H37Rv]
 gi|31792571|ref|NP_855064.1| putative transferase [Mycobacterium bovis AF2122/97]
 gi|121637307|ref|YP_977530.1| putative transferase [Mycobacterium bovis BCG str. Pasteur 1173P2]
 52 more sequence titles
 Length=212

 Score =  124 bits (311),  Expect = 1e-26, Method: Compositional matrix adjust.
 Identities = 77/197 (40%), Positives = 101/197 (52%), Gaps = 5/197 (2%)

Query  13   FEEMYRDDRVAHGLPAAT--PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA  70
            F+ +YR +    GLP  T  PWD   P+  V      G + G+VLD G G G +AIY A 
Sbjct  6    FDALYRGESPGEGLPPITTPPWDTKAPKDNVIGWHTGGWVHGDVLDIGCGLGDNAIYLAR  65

Query  71   KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST  130
             GY  TG+D S  A+  A+  A  AGV V F VGDAT L G  G FDTV+DC  +H    
Sbjct  66   NGYQVTGLDISPTALTTAKRRASDAGVDVKFAVGDATKLTGYTGAFDTVIDCGMFHCLDD  125

Query  131  APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRS-LSEDDFRQVLPVGGWEITY  189
              + +R Y  ++ RA++PGA L +  F          PRS +SE   R VL   GW+I  
Sbjct  126  --DGKRSYAASVHRATRPGATLLLSCFSNAMPPDEEWPRSTVSEQTLRDVLGGAGWDIES  183

Query  190  LGTTTYQVNLSVEALEL  206
            L   T +  L    +E+
Sbjct  184  LEPATVRRELDGTEVEM  200


>gi|118472427|ref|YP_887357.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
smegmatis str. MC2 155]
 gi|118173714|gb|ABK74610.1| thiopurine S-methyltransferase (tpmt) superfamily protein [Mycobacterium 
smegmatis str. MC2 155]
Length=225

 Score =  121 bits (303),  Expect = 1e-25, Method: Compositional matrix adjust.
 Identities = 76/188 (41%), Positives = 100/188 (54%), Gaps = 5/188 (2%)

Query  13   FEEMYRDDRVAHGLPAAT--PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA  70
            F+ +YR +  A G+P  T  PWD   P+  V      G + G VLD G G G +AIY A 
Sbjct  11   FDALYRGESPAEGVPPITSVPWDTKAPKENVVAWEQAGLVHGHVLDIGCGLGDNAIYLAQ  70

Query  71   KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST  130
            +GY  T +D S  A+  A   A  AGV V F V DAT LDG D  FDTVVD   +H  S 
Sbjct  71   QGYRVTALDISPTALITAERRAADAGVDVTFAVADATRLDGYDDVFDTVVDSGMFHCLS-  129

Query  131  APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRS-LSEDDFRQVLPVGGWEITY  189
              + +  Y  A+ RA++ GA L +  F + N+   +   + +SED  R  L  GGW+IT 
Sbjct  130  -DDAKGSYAAAVHRATRAGATLLLGAFSDANLQHDNWQAAWVSEDTLRSSLDDGGWDITS  188

Query  190  LGTTTYQV  197
            L T T +V
Sbjct  189  LTTETIRV  196


>gi|302527461|ref|ZP_07279803.1| conserved hypothetical protein [Streptomyces sp. AA4]
 gi|302436356|gb|EFL08172.1| conserved hypothetical protein [Streptomyces sp. AA4]
Length=210

 Score =  120 bits (300),  Expect = 2e-25, Method: Compositional matrix adjust.
 Identities = 65/159 (41%), Positives = 96/159 (61%), Gaps = 7/159 (4%)

Query  31   PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERARD  90
            PWD+G PQP + +L A GA RG VLD G G G +A++ AA G +  GID +  A+ +A++
Sbjct  28   PWDLGRPQPAIVELAAEGAFRGTVLDAGCGTGENALHLAASGLSIVGIDVAETAVAQAQE  87

Query  91   NARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKPGA  150
             AR+ G++  F VGDA  L  LD  FDTV+DC  +HTF    + ++ YV +L   ++PGA
Sbjct  88   KARRRGIAAEFAVGDAFRLSTLDRTFDTVLDCGLFHTFDA--QERQAYVASLASVTEPGA  145

Query  151  RLYMFEFGEHNVNGFSMP--RSLSEDDFRQVLPVGGWEI  187
            RL++  F E + +    P  R+  E  FR+     GW++
Sbjct  146  RLHVLCFRETDGDAGPHPVARTELEAPFRRET---GWQL  181


>gi|126179070|ref|YP_001047035.1| methyltransferase type 11 [Methanoculleus marisnigri JR1]
 gi|125861864|gb|ABN57053.1| Methyltransferase type 11 [Methanoculleus marisnigri JR1]
Length=195

 Score =  120 bits (300),  Expect = 2e-25, Method: Compositional matrix adjust.
 Identities = 66/184 (36%), Positives = 95/184 (52%), Gaps = 6/184 (3%)

Query  20   DRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGID  79
            D V HG P   PW+IG PQ    +L   G + G VLD G G G H +++A +G+   GID
Sbjct  5    DSVYHGTP---PWEIGRPQKAFVELARAGEVTGSVLDVGCGTGDHVLFFAEEGHEVLGID  61

Query  80   GSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYV  139
             +  AI +A + A   G+   F V DA  L GL+  FDTV+D  F+HT S   E +  +V
Sbjct  62   TAALAIRKAEEKAAGRGLQAQFLVRDALDLSGLERTFDTVIDSGFFHTLSD--EDRPVFV  119

Query  140  RALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQVNL  199
              L     PG R +M  FG+ N   + +PR ++E + R      GW I Y+    ++ ++
Sbjct  120  DNLAAVLAPGGRYFMLCFGDQNPGEYPLPRRIAEGEIRDAFR-DGWRINYIRPAIFENSI  178

Query  200  SVEA  203
              E 
Sbjct  179  QPEG  182


>gi|333991061|ref|YP_004523675.1| hypothetical protein JDM601_2421 [Mycobacterium sp. JDM601]
 gi|333487029|gb|AEF36421.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=139

 Score =  119 bits (297),  Expect = 5e-25, Method: Compositional matrix adjust.
 Identities = 63/95 (67%), Positives = 73/95 (77%), Gaps = 5/95 (5%)

Query  1   MTAQFDPA--DPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPG  58
           MT    P+  D  RFEE+YR    A GLPAATPWDIGG QPVV++LVALGAI+G VLDPG
Sbjct  1   MTGASGPSAGDAERFEEIYR---AAAGLPAATPWDIGGAQPVVRRLVALGAIKGAVLDPG  57

Query  59  TGPGHHAIYYAAKGYAATGIDGSVAAIERARDNAR  93
           TGPGHHA+++A  G+AATG+D S  AIE AR NAR
Sbjct  58  TGPGHHAVHFAEHGFAATGVDVSETAIEGARANAR  92


>gi|288916265|ref|ZP_06410644.1| Methyltransferase type 11 [Frankia sp. EUN1f]
 gi|288352244|gb|EFC86442.1| Methyltransferase type 11 [Frankia sp. EUN1f]
Length=225

 Score =  119 bits (297),  Expect = 6e-25, Method: Compositional matrix adjust.
 Identities = 73/193 (38%), Positives = 97/193 (51%), Gaps = 13/193 (6%)

Query  7    PADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAI  66
            P  PT F+  Y+      G P   PWDIG PQ   Q L   G +RG VLD G G G HA+
Sbjct  16   PRHPTDFDIFYQ------GTP---PWDIGRPQAAFQALANAGRLRGRVLDVGCGTGEHAL  66

Query  67   YYAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYH  126
              A+ G    G+D S  AIERA+  A + G+   F+V +A  L  L  RFDTV+DC  +H
Sbjct  67   LAASLGLDVVGVDTSALAIERAKAKAAERGLRARFRVENALRLADLPERFDTVLDCGLFH  126

Query  127  TFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWE  186
              +   E +  YVRAL     PG   YM  F +  V G   PR +S+D+ R      GW+
Sbjct  127  VLTD--EDREAYVRALHSVLHPGGHYYMLCFSDQ-VPGDIGPRRISQDEIRSSF-ADGWQ  182

Query  187  ITYLGTTTYQVNL  199
            +  +   T ++  
Sbjct  183  VDAVEPATLEITF  195


>gi|266631104|emb|CBH32104.1| putative dehydrogenase and domain with unknown function [Streptomyces 
albaduncus]
Length=761

 Score =  118 bits (295),  Expect = 1e-24, Method: Compositional matrix adjust.
 Identities = 88/222 (40%), Positives = 118/222 (54%), Gaps = 11/222 (4%)

Query  31   PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERARD  90
            PWDIG PQP +      G I G+VLD G G G +A + A +G+  T +D + AA+  AR 
Sbjct  549  PWDIGRPQPALVAAHDAGEITGDVLDVGCGLGDNAAFLAGRGHRVTAVDVAEAAVREARR  608

Query  91   NARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKPGA  150
             A  +GV V F V DAT L G DGRFDTVVD A +H+ S   E +R Y+RALR A++PG 
Sbjct  609  RAEDSGVDVEFAVADATRLTGYDGRFDTVVDSACFHSLSE-DERER-YLRALRTATRPGG  666

Query  151  RLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGG-WEITYLGTTTYQVNLSVEAL-ELMA  208
            RL+MF F +     F  P   +    R++  VGG W +  +   T+  +L VE +  L+ 
Sbjct  667  RLHMFCFAQEFEAPFPGPHRHTAASLREM--VGGVWNVLSVEAATFASSLGVEDIAALIE  724

Query  209  ARNPDMADQVRCVLERFRAIKPWLVGGRVHAPFWEVHATRVD  250
            +  PD  D     L+      P    G+   P W V A R D
Sbjct  725  SEYPD-GDVDPARLDGL----PLDEHGKATMPVWHVTAERRD  761


>gi|126180199|ref|YP_001048164.1| methyltransferase type 11 [Methanoculleus marisnigri JR1]
 gi|125862993|gb|ABN58182.1| Methyltransferase type 11 [Methanoculleus marisnigri JR1]
Length=196

 Score =  116 bits (290),  Expect = 3e-24, Method: Compositional matrix adjust.
 Identities = 63/190 (34%), Positives = 96/190 (51%), Gaps = 12/190 (6%)

Query  13   FEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKG  72
            F+ +YR         +  PWDIG PQ    +L   G I G VLD G G G H +++A +G
Sbjct  4    FDSVYR---------STPPWDIGRPQKAFVELARAGEITGSVLDIGCGTGDHVLFFAGEG  54

Query  73   YAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAP  132
            +   GID +  AI +AR+ A K G+   F VG+A  L  L+  FDTV+D   +HT S   
Sbjct  55   HEVLGIDTASLAIRKAREKAAKRGLQAQFFVGNALELSALNRTFDTVIDSGLFHTLSD--  112

Query  133  ELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGT  192
            E +     +L     PG R +M  F E N   + +PR +++D+ +      GW I Y+  
Sbjct  113  EDRPALAESLAAVLAPGGRYFMLCFNEQNPGEYPLPRRITQDEIQDAFR-DGWVINYIRP  171

Query  193  TTYQVNLSVE  202
              ++ ++  +
Sbjct  172  AVFENSIQAD  181


>gi|315445419|ref|YP_004078298.1| methylase involved in ubiquinone/menaquinone biosynthesis [Mycobacterium 
sp. Spyr1]
 gi|315263722|gb|ADU00464.1| methylase involved in ubiquinone/menaquinone biosynthesis [Mycobacterium 
sp. Spyr1]
Length=212

 Score =  116 bits (290),  Expect = 3e-24, Method: Compositional matrix adjust.
 Identities = 68/186 (37%), Positives = 98/186 (53%), Gaps = 12/186 (6%)

Query  11   TRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA  70
            +RF++ Y+D+          PW IG PQP V  +   G I G VLD G G G H I   A
Sbjct  8    SRFDDFYKDED------QTPPWVIGEPQPAVVDIERAGLITGRVLDVGCGTGEHTILLTA  61

Query  71   KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST  130
             GY   G+DG+ +A+E+AR NA+  G+   F V DA  L G +  +DT++D A +H F  
Sbjct  62   AGYDVLGVDGAPSAVEQARHNAKTRGIDARFDVADALDL-GDEPAYDTIIDSALFHIFDD  120

Query  131  APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYL  190
            A   +  YVR+L RA+ PG+ +++    +    G      +SE+  R      GW+I  L
Sbjct  121  AD--REKYVRSLGRATAPGSVVHLLALSD---TGRGFGPEVSEETIRAAFADPGWDIEAL  175

Query  191  GTTTYQ  196
             TT Y+
Sbjct  176  TTTYYR  181


>gi|183982206|ref|YP_001850497.1| NodS-like (sam)-dependent methyltransferase [Mycobacterium marinum 
M]
 gi|183175532|gb|ACC40642.1| NodS-like (sam)-dependent methyltransferase [Mycobacterium marinum 
M]
Length=211

 Score =  115 bits (289),  Expect = 4e-24, Method: Compositional matrix adjust.
 Identities = 76/190 (40%), Positives = 96/190 (51%), Gaps = 5/190 (2%)

Query  13   FEEMYRDDRVAHGLPAAT--PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA  70
            F+ +YR +    G+   T  PWD   P+  V    A G + G+VLD G G G +AIY AA
Sbjct  3    FDALYRGESPRPGVAPMTTPPWDTKAPKENVIAWQAGGWVHGDVLDIGCGLGDNAIYLAA  62

Query  71   KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST  130
             G+  TG+D S  A+  A   A  AGV V F V DAT LDG    FDTV+D   +H    
Sbjct  63   HGHPVTGLDISPTALITAARRADDAGVHVTFAVADATKLDGYTDAFDTVIDSGMFHCLDD  122

Query  131  APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPR-SLSEDDFRQVLPVGGWEITY  189
              E +R Y  A+ RA++PGA L M  F + N      PR ++ E   R VL   GWEI  
Sbjct  123  --EGKRSYAAAVHRATRPGATLLMSCFCDANPPNEQQPRPAVPEQTLRDVLGGAGWEIAA  180

Query  190  LGTTTYQVNL  199
            L   T    L
Sbjct  181  LDPVTVNRQL  190


>gi|325675063|ref|ZP_08154749.1| thiopurine S-methyltransferase family protein [Rhodococcus equi 
ATCC 33707]
 gi|325554024|gb|EGD23700.1| thiopurine S-methyltransferase family protein [Rhodococcus equi 
ATCC 33707]
Length=253

 Score =  115 bits (287),  Expect = 7e-24, Method: Compositional matrix adjust.
 Identities = 77/205 (38%), Positives = 109/205 (54%), Gaps = 16/205 (7%)

Query  13   FEEMYRDDRVAHGLPAA----------TPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPG  62
            F+ +YR D  A    A            PWDIG  QP V+ L + G    EVLD G GPG
Sbjct  17   FDALYRGDFAAVNADAEPTAPGFTFDRVPWDIGEAQPAVRALESSGQFAREVLDIGCGPG  76

Query  63   HHAIYYAAKGYAATGIDGSVAAIERARDNARKAGVS--VNFQVGDATTLDGLDGRFDTVV  120
             +A++ A++GY   G+D + AAI+ AR+ AR+ G+   V F+V DAT L     RF +V+
Sbjct  77   ENALFLASRGYRVWGLDAAPAAIDIARERARQRGMERGVEFEVADATDLSDYADRFVSVI  136

Query  121  DCAFYHTFSTAPELQRC-YVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQV  179
            D A YH F   PE QR  Y  +L  A +P ARL++  F +   +GF  P  ++ED+ R  
Sbjct  137  DSALYHCF---PEDQRHRYAASLFGACRPQARLHVVCFSDRVPDGFPGPYRITEDNLRDT  193

Query  180  LPVGGWEITYLGTTTYQVNLSVEAL  204
            L   GW +  +  TTY    + + +
Sbjct  194  LTAAGWTVQRIEPTTYTTAFTRDEM  218


>gi|296170757|ref|ZP_06852329.1| thiopurine S-methyltransferase family protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
 gi|295894572|gb|EFG74309.1| thiopurine S-methyltransferase family protein [Mycobacterium 
parascrofulaceum ATCC BAA-614]
Length=225

 Score =  114 bits (285),  Expect = 1e-23, Method: Compositional matrix adjust.
 Identities = 71/197 (37%), Positives = 100/197 (51%), Gaps = 5/197 (2%)

Query  13   FEEMYRDDRVAHGLP--AATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA  70
            F+ +YR +    G+P  A  PWD   P+  V      G + G+VLD G G G +AIY A 
Sbjct  21   FDALYRGESPGEGIPPMATPPWDTKAPKDSVVAWHGGGWVHGDVLDIGCGLGDNAIYLAR  80

Query  71   KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST  130
             G+  TG+D S  A+  A+  A +AG  V F V DAT L+G    FDTV+D   +H    
Sbjct  81   NGFRVTGLDISATALVTAQRRAHEAGADVTFAVADATKLEGFTDAFDTVIDSGMFHCLDD  140

Query  131  APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPR-SLSEDDFRQVLPVGGWEITY  189
              + +R Y  A+ RA++PGA L +  F + N      PR S+SE   R VL    W+I  
Sbjct  141  --DGKRSYAAAVHRATRPGATLLISCFSDANGPDERWPRPSVSEQTLRDVLGGAAWDIES  198

Query  190  LGTTTYQVNLSVEALEL  206
            L   T +  +    +E+
Sbjct  199  LEPATMRREVDGAQVEM  215


>gi|312137777|ref|YP_004005113.1| SAM dependent methyltransferase [Rhodococcus equi 103S]
 gi|311887116|emb|CBH46425.1| putative SAM dependent methyltransferase [Rhodococcus equi 103S]
Length=255

 Score =  114 bits (285),  Expect = 1e-23, Method: Compositional matrix adjust.
 Identities = 76/200 (38%), Positives = 108/200 (54%), Gaps = 14/200 (7%)

Query  8    ADPTRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIY  67
            A+PT     +  DRV        PWDIG  QP V+ L + G    EVLD G GPG +A++
Sbjct  32   AEPTETAPGFTFDRV--------PWDIGEAQPAVRALESSGQFAREVLDIGCGPGENALF  83

Query  68   YAAKGYAATGIDGSVAAIERARDNARKAGVS--VNFQVGDATTLDGLDGRFDTVVDCAFY  125
             A++GY   G+D + AAI+ AR+ AR+ G+   V F+V DAT L     RF +V+D A Y
Sbjct  84   LASRGYRVWGLDAAPAAIDIARERARQRGMERGVEFEVADATDLSDYADRFASVIDSALY  143

Query  126  HTFSTAPELQRC-YVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGG  184
            H F   PE QR  Y  +L  A +P ARL++  F +   +GF  P  ++ED+ R  L   G
Sbjct  144  HCF---PEDQRHRYAASLFGACRPQARLHVVCFSDRVPDGFPGPYRITEDNLRDTLTAAG  200

Query  185  WEITYLGTTTYQVNLSVEAL  204
            W +  +  T Y    + + +
Sbjct  201  WTVQRIEPTIYTTAFTRDEM  220


>gi|240170754|ref|ZP_04749413.1| hypothetical protein MkanA1_15682 [Mycobacterium kansasii ATCC 
12478]
Length=239

 Score =  114 bits (285),  Expect = 1e-23, Method: Compositional matrix adjust.
 Identities = 72/197 (37%), Positives = 98/197 (50%), Gaps = 5/197 (2%)

Query  13   FEEMYRDDRVAHGLPAAT--PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA  70
            F+ +YR +    G+P  T  PWD   P+  V      G + GEVLD G G G +AIY A 
Sbjct  32   FDALYRGESPGPGIPPMTTPPWDTKAPKENVIAWQTGGWVHGEVLDIGCGFGDNAIYLAQ  91

Query  71   KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST  130
             G+  T +D S  A+  A   A  AGV V F   DATTLDG   RFDTV+D   +H    
Sbjct  92   HGHRVTAMDISPTALITAERRAADAGVDVRFAAADATTLDGYTDRFDTVIDSGMFHCLDD  151

Query  131  APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPR-SLSEDDFRQVLPVGGWEITY  189
              + +R Y  A+ RA++PGA L +  F + N      PR ++SE   R VL    W++  
Sbjct  152  --DGKRSYAAAVHRATRPGATLLISCFSDANPPNEQWPRPAVSEQTLRDVLGGAAWDVES  209

Query  190  LGTTTYQVNLSVEALEL  206
            L   T +  +     E+
Sbjct  210  LEPVTVRREMDGTETEM  226


>gi|120402886|ref|YP_952715.1| type 11 methyltransferase [Mycobacterium vanbaalenii PYR-1]
 gi|119955704|gb|ABM12709.1| Methyltransferase type 11 [Mycobacterium vanbaalenii PYR-1]
Length=209

 Score =  113 bits (283),  Expect = 2e-23, Method: Compositional matrix adjust.
 Identities = 74/201 (37%), Positives = 103/201 (52%), Gaps = 18/201 (8%)

Query  11   TRFEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAA  70
            +RF+E Y++           PW IG PQ  + +L   G I G VLD G G G H I  A 
Sbjct  8    SRFDEFYKNQ--------TPPWVIGEPQQAIVELEQAGLIGGRVLDVGCGTGEHTILLAR  59

Query  71   KGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFST  130
             GY   GIDG+  A+E+AR NA   GV   F++ DA  L G D  +DT+VD A +H F  
Sbjct  60   AGYDVLGIDGAPTAVEQARRNAEAQGVDARFELADALHL-GPDPTYDTIVDSALFHIFDD  118

Query  131  APELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYL  190
            A   +  YVR+L  A++PG+ +++    +   +G      +SE   R      GWE+  L
Sbjct  119  AD--RATYVRSLHAATRPGSVVHLLALSD---SGRGFGPEVSEHTIRAAFG-AGWEVEAL  172

Query  191  GTTTYQ---VNLSVEALELMA  208
              TTY+   ++   EAL L A
Sbjct  173  TETTYRGVVIDAHTEALNLPA  193


>gi|134098593|ref|YP_001104254.1| methyltransferase type 11 [Saccharopolyspora erythraea NRRL 2338]
 gi|291008210|ref|ZP_06566183.1| methyltransferase type 11 [Saccharopolyspora erythraea NRRL 2338]
 gi|133911216|emb|CAM01329.1| methyltransferase type 11 [Saccharopolyspora erythraea NRRL 2338]
Length=209

 Score =  112 bits (279),  Expect = 6e-23, Method: Compositional matrix adjust.
 Identities = 74/166 (45%), Positives = 93/166 (57%), Gaps = 7/166 (4%)

Query  31   PWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERARD  90
            PW IG PQP V +L   GAIRG VLD GTG G H I+ A  GY   G+D S  A+E+AR 
Sbjct  20   PWVIGEPQPAVVELERTGAIRGAVLDAGTGAGEHTIHLAELGYDVLGVDFSPFAVEQARA  79

Query  91   NARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKPGA  150
            NAR  GV   F+V DA  L G   RFDTV+D A +H F  A E QR Y R+L    +PGA
Sbjct  80   NARARGVEARFEVADALGL-GTQERFDTVLDSALFHVFG-AEERQR-YTRSLHAVCRPGA  136

Query  151  RLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQ  196
             +++    +    GF  PR +S+   R      GWE+  L  + Y+
Sbjct  137  VVHVLALSDAE-PGFG-PR-ISDQVIRDAF-ADGWELEDLRPSRYR  178


>gi|119867652|ref|YP_937604.1| type 11 methyltransferase [Mycobacterium sp. KMS]
 gi|126434151|ref|YP_001069842.1| type 11 methyltransferase [Mycobacterium sp. JLS]
 gi|119693741|gb|ABL90814.1| Methyltransferase type 11 [Mycobacterium sp. KMS]
 gi|126233951|gb|ABN97351.1| Methyltransferase type 11 [Mycobacterium sp. JLS]
Length=210

 Score =  111 bits (278),  Expect = 8e-23, Method: Compositional matrix adjust.
 Identities = 72/168 (43%), Positives = 88/168 (53%), Gaps = 7/168 (4%)

Query  29   ATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERA  88
            A PW IG PQP V  L   GAI G VLD G G G H I     GY   G+D S  A+E A
Sbjct  19   AAPWVIGEPQPAVVDLERRGAISGAVLDAGCGAGEHTILLTGLGYDVLGVDFSARAVELA  78

Query  89   RDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKP  148
            R NA   GV+  F+V DAT LDG   RFDTVVD A +H F      +R YV +L    +P
Sbjct  79   RANAAARGVNARFEVADATRLDG-GPRFDTVVDSALFHVFDDID--RRRYVDSLASVCRP  135

Query  149  GARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQ  196
            GA +++    +    GF     +SE D R      GW +  + TTTY+
Sbjct  136  GAVVHILALSDAG-RGFGP--QVSEADIRTAF-TDGWRVESVETTTYR  179


>gi|118468119|ref|YP_886428.1| methyltransferase type 12 [Mycobacterium smegmatis str. MC2 155]
 gi|118169406|gb|ABK70302.1| methyltransferase type 12 [Mycobacterium smegmatis str. MC2 155]
Length=211

 Score =  111 bits (278),  Expect = 9e-23, Method: Compositional matrix adjust.
 Identities = 76/190 (40%), Positives = 98/190 (52%), Gaps = 17/190 (8%)

Query  10   PTR--FEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIY  67
            PTR  F+E Y + R A       PW IG PQP V +L   G IR  VLD G G G H I 
Sbjct  5    PTRELFDEAY-ESRTA-------PWVIGEPQPAVVELERAGLIRSRVLDVGCGAGEHTIL  56

Query  68   YAAKGYAATGIDGSVAAIERARDNARKAGVSVNFQVGDATTLDGL-DGRFDTVVDCAFYH  126
                GY   GID S  AIE AR+NAR  GV   F VGDA  L  L DG +DT++D A +H
Sbjct  57   LTRLGYDVLGIDFSPQAIEMARENARGRGVDARFAVGDAMALGDLGDGAYDTILDSALFH  116

Query  127  TFSTAPELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWE  186
             F  A   ++ YV +L    +PG  +++    +    G      +SE+  R+     GW+
Sbjct  117  IFDDAD--RQTYVASLHAGCRPGGTVHILALSD---AGRGFGPEVSEEQIRKAFG-DGWD  170

Query  187  ITYLGTTTYQ  196
            +  L TTTY+
Sbjct  171  LEALETTTYR  180


>gi|108798553|ref|YP_638750.1| type 11 methyltransferase [Mycobacterium sp. MCS]
 gi|108768972|gb|ABG07694.1| Methyltransferase type 11 [Mycobacterium sp. MCS]
Length=197

 Score =  111 bits (278),  Expect = 9e-23, Method: Compositional matrix adjust.
 Identities = 72/168 (43%), Positives = 88/168 (53%), Gaps = 7/168 (4%)

Query  29   ATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAIERA  88
            A PW IG PQP V  L   GAI G VLD G G G H I     GY   G+D S  A+E A
Sbjct  6    AAPWVIGEPQPAVVDLERRGAISGAVLDAGCGAGEHTILLTGLGYDVLGVDFSARAVELA  65

Query  89   RDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRASKP  148
            R NA   GV+  F+V DAT LDG   RFDTVVD A +H F      +R YV +L    +P
Sbjct  66   RANAAARGVNARFEVADATRLDG-GPRFDTVVDSALFHVFDDID--RRRYVDSLASVCRP  122

Query  149  GARLYMFEFGEHNVNGFSMPRSLSEDDFRQVLPVGGWEITYLGTTTYQ  196
            GA +++    +    GF     +SE D R      GW +  + TTTY+
Sbjct  123  GAVVHILALSDAG-RGFGP--QVSEADIRTAF-TDGWRVESVETTTYR  166


>gi|153003070|ref|YP_001377395.1| type 12 methyltransferase [Anaeromyxobacter sp. Fw109-5]
 gi|152026643|gb|ABS24411.1| Methyltransferase type 12 [Anaeromyxobacter sp. Fw109-5]
Length=198

 Score =  111 bits (277),  Expect = 1e-22, Method: Compositional matrix adjust.
 Identities = 63/152 (42%), Positives = 85/152 (56%), Gaps = 3/152 (1%)

Query  26   LPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKGYAATGIDGSVAAI  85
            L  + PWDIG PQP + +L   G ++G VLD G G G +A++ A+ G    G+DGS AAI
Sbjct  14   LAGSPPWDIGRPQPEIVKLADEGEVKGTVLDVGCGTGENALHLASLGKRVVGVDGSRAAI  73

Query  86   ERARDNARKAGVSVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTAPELQRCYVRALRRA  145
             RAR+ A + G+ V F V DA  L  L  R +TVVDC  +H FS   E +R Y  +L   
Sbjct  74   ARAREKAAERGLPVAFHVADALQLRRLHLRVETVVDCGLFHVFSD--EERRPYAESLTEV  131

Query  146  SKPGARLYMFEFGEHNVNGFSMPRSLSEDDFR  177
              PG  L++  F +    G   PR ++E D R
Sbjct  132  LSPGGTLHVLCFSDEEPPG-PGPRRVAEYDLR  162


>gi|41406223|ref|NP_959059.1| hypothetical protein MAP0125c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41394571|gb|AAS02442.1| hypothetical protein MAP_0125c [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=231

 Score =  111 bits (277),  Expect = 1e-22, Method: Compositional matrix adjust.
 Identities = 60/169 (36%), Positives = 93/169 (56%), Gaps = 3/169 (1%)

Query  13   FEEMYRDDRVAHGLPAATPWDIGGPQPVVQQLVALGAIRGEVLDPGTGPGHHAIYYAAKG  72
            FE  YR +    G  A  PW IG PQP +  L+  G   G+VLD G G    ++Y A +G
Sbjct  11   FEAAYRGESPEMGEGARPPWSIGEPQPEIAALIEAGKFHGDVLDAGCGEAAVSLYLAERG  70

Query  73   YAATGIDGSVAAIERARDNARKAGV-SVNFQVGDATTLDGLDGRFDTVVDCAFYHTFSTA  131
            +   G+D S  AI+ AR+ A + G+ S +F+V D +   G DGRF T+VD   +H+    
Sbjct  71   FTTVGLDQSPTAIKLAREKAARRGLTSASFEVADISDFTGYDGRFGTIVDSTLFHSMPV-  129

Query  132  PELQRCYVRALRRASKPGARLYMFEFGEHNVNGFSMPRSLSEDDFRQVL  180
             EL+  Y R++ RA+ PGA  ++  F  + +       +++ED+ R+V+
Sbjct  130  -ELREGYQRSIVRAAAPGASYFVLVFDRNAMPAEGPVNAVTEDELREVV  177



Lambda     K      H
   0.322    0.138    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 358945203960


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40