BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2677c Length=452 Score E Sequences producing significant alignments: (Bits) Value gi|15842215|ref|NP_337252.1| protoporphyrinogen oxidase [Mycobac... 872 0.0 gi|289751329|ref|ZP_06510707.1| protoporphyrinogen oxidase hemY ... 870 0.0 gi|340627678|ref|YP_004746130.1| putative protoporphyrinogen oxi... 868 0.0 gi|339295539|gb|AEJ47650.1| protoporphyrinogen oxidase [Mycobact... 839 0.0 gi|7478123|pir||F70869 probable hemY' - Mycobacterium tuberculos... 824 0.0 gi|254551732|ref|ZP_05142179.1| protoporphyrinogen oxidase [Myco... 709 0.0 gi|15827507|ref|NP_301770.1| protoporphyrinogen oxidase [Mycobac... 645 0.0 gi|289570853|ref|ZP_06451080.1| LOW QUALITY PROTEIN: protoporphy... 641 0.0 gi|183982052|ref|YP_001850343.1| protoporphyrinogen oxidase HemY... 622 3e-176 gi|342858452|ref|ZP_08715107.1| protoporphyrinogen oxidase [Myco... 619 3e-175 gi|118618641|ref|YP_906973.1| protoporphyrinogen oxidase [Mycoba... 618 8e-175 gi|240169728|ref|ZP_04748387.1| protoporphyrinogen oxidase [Myco... 612 4e-173 gi|41408896|ref|NP_961732.1| protoporphyrinogen oxidase [Mycobac... 572 4e-161 gi|254365339|ref|ZP_04981384.1| protoporphyrinogen oxidase hemY ... 569 3e-160 gi|289758805|ref|ZP_06518183.1| LOW QUALITY PROTEIN: protoporphy... 547 1e-153 gi|118467902|ref|YP_887112.1| protoporphyrinogen oxidase [Mycoba... 536 4e-150 gi|108799180|ref|YP_639377.1| protoporphyrinogen oxidase [Mycoba... 527 2e-147 gi|126434788|ref|YP_001070479.1| protoporphyrinogen oxidase [Myc... 526 4e-147 gi|333991063|ref|YP_004523677.1| protoporphyrinogen oxidase HemY... 519 5e-145 gi|120403472|ref|YP_953301.1| protoporphyrinogen oxidase [Mycoba... 509 5e-142 gi|289746477|ref|ZP_06505855.1| protoporphyrinogen oxidase hemY ... 508 8e-142 gi|315444830|ref|YP_004077709.1| protoporphyrinogen oxidase [Myc... 506 3e-141 gi|145224499|ref|YP_001135177.1| protoporphyrinogen oxidase [Myc... 505 6e-141 gi|289746478|ref|ZP_06505856.1| protoporphyrinogen oxidase [Myco... 494 2e-137 gi|307080778|ref|ZP_07489948.1| hypothetical protein TMKG_03106 ... 486 3e-135 gi|323718737|gb|EGB27898.1| protoporphyrinogen oxidase [Mycobact... 462 4e-128 gi|308371093|ref|ZP_07423804.2| protoporphyrinogen oxidase hemY ... 442 6e-122 gi|307085370|ref|ZP_07494483.1| hypothetical protein TMLG_02390 ... 441 1e-121 gi|308371094|ref|ZP_07667088.1| hypothetical protein TMCG_01924 ... 437 2e-120 gi|169630068|ref|YP_001703717.1| protoporphyrinogen oxidase [Myc... 435 9e-120 gi|289444219|ref|ZP_06433963.1| protoporphyrinogen oxidase [Myco... 414 1e-113 gi|323718672|gb|EGB27834.1| protoporphyrinogen oxidase [Mycobact... 400 3e-109 gi|226366253|ref|YP_002784036.1| protoporphyrinogen oxidase [Rho... 398 1e-108 gi|111023817|ref|YP_706789.1| protoporphyrinogen oxidase [Rhodoc... 380 2e-103 gi|226306335|ref|YP_002766295.1| protoporphyrinogen oxidase [Rho... 370 3e-100 gi|308380437|ref|ZP_07669194.1| hypothetical protein TMKG_03107 ... 368 1e-99 gi|229491251|ref|ZP_04385077.1| protoporphyrinogen oxidase [Rhod... 359 6e-97 gi|326904291|gb|EGE51224.1| LOW QUALITY PROTEIN: protoporphyrino... 353 2e-95 gi|54025707|ref|YP_119949.1| protoporphyrinogen oxidase [Nocardi... 342 8e-92 gi|333919449|ref|YP_004493030.1| protoporphyrinogen oxidase [Amy... 340 3e-91 gi|312139467|ref|YP_004006803.1| protoporphyrinogen oxidase hemg... 338 1e-90 gi|325672645|ref|ZP_08152341.1| protoporphyrinogen oxidase [Rhod... 337 3e-90 gi|343924650|ref|ZP_08764194.1| protoporphyrinogen oxidase [Gord... 333 3e-89 gi|289762848|ref|ZP_06522226.1| protoporphyrinogen oxidase hemY ... 333 4e-89 gi|262202197|ref|YP_003273405.1| protoporphyrinogen oxidase [Gor... 326 6e-87 gi|296171935|ref|ZP_06852980.1| protoporphyrinogen oxidase [Myco... 319 7e-85 gi|296139602|ref|YP_003646845.1| protoporphyrinogen oxidase [Tsu... 317 3e-84 gi|167970101|ref|ZP_02552378.1| protoporphyrinogen oxidase [Myco... 312 8e-83 gi|326384416|ref|ZP_08206096.1| protoporphyrinogen oxidase [Gord... 306 4e-81 gi|254821719|ref|ZP_05226720.1| protoporphyrinogen oxidase [Myco... 293 6e-77 >gi|15842215|ref|NP_337252.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis CDC1551] gi|31793849|ref|NP_856342.1| protoporphyrinogen oxidase [Mycobacterium bovis AF2122/97] gi|57117012|ref|YP_177675.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis H37Rv] 48 more sequence titles Length=452 Score = 872 bits (2253), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/452 (100%), Positives = 452/452 (100%), Gaps = 0/452 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL Sbjct 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA Sbjct 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 Query 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA Sbjct 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 Query 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS 360 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS Sbjct 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS 360 Query 361 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG 420 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG Sbjct 361 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG 420 Query 421 SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR Sbjct 421 SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 >gi|289751329|ref|ZP_06510707.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis T92] gi|289754779|ref|ZP_06514157.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis EAS054] gi|289691916|gb|EFD59345.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis T92] gi|289695366|gb|EFD62795.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis EAS054] Length=452 Score = 870 bits (2247), Expect = 0.0, Method: Compositional matrix adjust. Identities = 451/452 (99%), Positives = 452/452 (100%), Gaps = 0/452 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGD+VVARSVDPLLSGVYAGSAATIGL Sbjct 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDRVVARSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA Sbjct 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 Query 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA Sbjct 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 Query 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS 360 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS Sbjct 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS 360 Query 361 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG 420 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG Sbjct 361 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG 420 Query 421 SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR Sbjct 421 SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 >gi|340627678|ref|YP_004746130.1| putative protoporphyrinogen oxidase HEMY [Mycobacterium canettii CIPT 140010059] gi|340005868|emb|CCC45034.1| putative protoporphyrinogen oxidase HEMY (protoporphyrinogen-IX oxidase) (protoporphyrinogenase) (PPO) [Mycobacterium canettii CIPT 140010059] Length=452 Score = 868 bits (2242), Expect = 0.0, Method: Compositional matrix adjust. Identities = 451/452 (99%), Positives = 451/452 (99%), Gaps = 0/452 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL Sbjct 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA Sbjct 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 Query 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA Sbjct 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 Query 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS 360 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDE ALTAS Sbjct 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDELALTAS 360 Query 361 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG 420 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG Sbjct 361 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG 420 Query 421 SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR Sbjct 421 SYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 >gi|339295539|gb|AEJ47650.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis CCDC5079] gi|339299157|gb|AEJ51267.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis CCDC5180] Length=437 Score = 839 bits (2167), Expect = 0.0, Method: Compositional matrix adjust. Identities = 436/437 (99%), Positives = 437/437 (100%), Gaps = 0/437 (0%) Query 16 LTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAE 75 +TSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAE Sbjct 1 MTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAE 60 Query 76 LGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARP 135 LGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARP Sbjct 61 LGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARP 120 Query 136 FTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGA 195 FTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGA Sbjct 121 FTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGA 180 Query 196 TSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDET 255 TSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDET Sbjct 181 TSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDET 240 Query 256 GGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGV 315 GGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGV Sbjct 241 GGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGV 300 Query 316 LVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTV 375 LVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTV Sbjct 301 LVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTV 360 Query 376 FGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAA 435 FGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAA Sbjct 361 FGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAA 420 Query 436 GRAVTSVIEALDAQVAR 452 GRAVTSVIEALDAQVAR Sbjct 421 GRAVTSVIEALDAQVAR 437 >gi|7478123|pir||F70869 probable hemY' - Mycobacterium tuberculosis (strain H37RV) Length=426 Score = 824 bits (2129), Expect = 0.0, Method: Compositional matrix adjust. Identities = 426/426 (100%), Positives = 426/426 (100%), Gaps = 0/426 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL Sbjct 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA Sbjct 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 Query 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA Sbjct 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 Query 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS 360 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS Sbjct 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTAS 360 Query 361 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG 420 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG Sbjct 361 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAG 420 Query 421 SYLDGI 426 SYLDGI Sbjct 421 SYLDGI 426 >gi|254551732|ref|ZP_05142179.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] Length=383 Score = 709 bits (1829), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/371 (100%), Positives = 371/371 (100%), Gaps = 0/371 (0%) Query 82 QLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFTWQVG 141 QLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFTWQVG Sbjct 13 QLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFTWQVG 72 Query 142 SDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDA 201 SDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDA Sbjct 73 SDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDA 132 Query 202 VRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQA 261 VRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQA Sbjct 133 VRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQA 192 Query 262 DAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDE 321 DAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDE Sbjct 193 DAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDE 252 Query 322 SPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVD 381 SPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVD Sbjct 253 SPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVD 312 Query 382 PVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTS 441 PVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTS Sbjct 313 PVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTS 372 Query 442 VIEALDAQVAR 452 VIEALDAQVAR Sbjct 373 VIEALDAQVAR 383 >gi|15827507|ref|NP_301770.1| protoporphyrinogen oxidase [Mycobacterium leprae TN] gi|221229984|ref|YP_002503400.1| protoporphyrinogen oxidase [Mycobacterium leprae Br4923] gi|3914415|sp|Q50008.1|PPOX_MYCLE RecName: Full=Protoporphyrinogen oxidase; Short=PPO gi|699193|gb|AAA62958.1| hemY [Mycobacterium leprae] gi|13093057|emb|CAC31425.1| protoporphyrinogen oxidase [Mycobacterium leprae] gi|219933091|emb|CAR71139.1| protoporphyrinogen oxidase [Mycobacterium leprae Br4923] Length=451 Score = 645 bits (1665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/455 (76%), Positives = 381/455 (84%), Gaps = 7/455 (1%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MT RSYCVVGGGISGLT+AYRLR A GDD ITLF+P DRLGGVLRTE +GGQPMDLGAE Sbjct 1 MTSRSYCVVGGGISGLTAAYRLRVATGDDVAITLFDPGDRLGGVLRTECVGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AF+LRRPE+PALLAELGLS+RQ A+T ARPLIYSQQRLH LPP TV GIPSSA S+AGLV Sbjct 61 AFLLRRPEVPALLAELGLSERQRATTDARPLIYSQQRLHSLPPDTVAGIPSSATSVAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDAT+ARI AEA RP +W+ GSDPA+A+LVADRFG+Q VAR VDPLL GVYAGSAATIGL Sbjct 121 DDATVARIGAEAVRPLSWEPGSDPAMAELVADRFGEQAVARLVDPLLGGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RA APSVAAALD GATS+ +AVRQ LPP + GPVFGALDGGYQVL+D LVRRSR+ WV A Sbjct 181 RAGAPSVAAALDCGATSLMEAVRQGLPPVAAGPVFGALDGGYQVLIDELVRRSRLQWVAA 240 Query 241 RVVQLER---GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSA 297 VV L+R GW L D+TG W AD VILAVPAPRL RL+ IAPRT AAA +IVSASSA Sbjct 241 TVVGLDRGTCGWTLVDDTGACWSADGVILAVPAPRLVRLLQQIAPRTVAAASRIVSASSA 300 Query 298 VVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPAL 357 VVAL+VP T FP SGVLVA E AKA+TLSSRKWG +GD L+RLSFG+FGD+ A Sbjct 301 VVALSVPRDTTFPQNSGVLVASGERLRAKAVTLSSRKWGLQGDTQLVRLSFGKFGDQVAS 360 Query 358 TASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLA 417 TASDD+LLAWA DL VF V VDPVDV V+RWI+AMPQYGPGHAD+VAE+RAGLPPTL Sbjct 361 TASDDELLAWAVSDLAAVFDVTVDPVDVCVQRWIDAMPQYGPGHADLVAEVRAGLPPTLV 420 Query 418 VAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 VAGS++DGIGVPAC+ AAGRA IEAL A+VAR Sbjct 421 VAGSHMDGIGVPACISAAGRA----IEALQAEVAR 451 >gi|289570853|ref|ZP_06451080.1| LOW QUALITY PROTEIN: protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis T17] gi|289544607|gb|EFD48255.1| LOW QUALITY PROTEIN: protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis T17] Length=358 Score = 641 bits (1653), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/351 (98%), Positives = 344/351 (99%), Gaps = 0/351 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGD+VVARSVDPLLSGVYAGSAATIGL Sbjct 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDRVVARSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA Sbjct 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 Query 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA Sbjct 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 Query 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRF 351 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWG +RLSFGRF Sbjct 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGSARRRRAVRLSFGRF 351 >gi|183982052|ref|YP_001850343.1| protoporphyrinogen oxidase HemY [Mycobacterium marinum M] gi|183175378|gb|ACC40488.1| protoporphyrinogen oxidase HemY [Mycobacterium marinum M] Length=455 Score = 622 bits (1605), Expect = 3e-176, Method: Compositional matrix adjust. Identities = 333/455 (74%), Positives = 382/455 (84%), Gaps = 3/455 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTP SYCVVGGGISGLT+A+RLR AVG+DA ITL +P+DRLGG+LRTE +GGQPMDLGAE Sbjct 1 MTPGSYCVVGGGISGLTAAFRLRLAVGEDALITLLDPSDRLGGILRTERVGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFV+RRPEMPALLAELGLS Q ++TGARPLIYS Q LHPLP TV+GIP+SA S+AGLV Sbjct 61 AFVVRRPEMPALLAELGLSGLQRSTTGARPLIYSCQELHPLPTGTVMGIPASARSLAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDAT+A+I+AE RP W+ G DPAVA+LVA+RFG+Q V RSVDPLL GVYAGSAATIG+ Sbjct 121 DDATIAQIEAEPDRPLHWRPGGDPAVAELVAERFGEQTVTRSVDPLLCGVYAGSAATIGV 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RAA P+VAAALDRGATS+T+AVRQ+LPP S GPVFGAL GGYQVL++ LV RS V WV+A Sbjct 181 RAAIPAVAAALDRGATSLTEAVRQSLPPASVGPVFGALTGGYQVLVEELVARSGVQWVQA 240 Query 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARL---VDGIAPRTHAAARQIVSASSA 297 V ++E GW L D+ G RW ADAVILA+PAPRL R+ VDG+ PR+ AAA ++ SASSA Sbjct 241 AVSKIEPGWALHDDAGRRWHADAVILAIPAPRLVRILDGVDGVDPRSVAAASRVRSASSA 300 Query 298 VVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPAL 357 VVALAVP T FP CSGVLVA E AKAITLSSRKWG +GDV LR+SFGRFGD+ A Sbjct 301 VVALAVPADTPFPQCSGVLVANGEPLRAKAITLSSRKWGIQGDVQQLRISFGRFGDDLAE 360 Query 358 TASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLA 417 SD QLL+WA DDL TVFGV VDPVD RV+RWIEAMPQYGPGH ++VA++RAGLPPTLA Sbjct 361 RVSDHQLLSWARDDLATVFGVTVDPVDSRVQRWIEAMPQYGPGHGELVAQVRAGLPPTLA 420 Query 418 VAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 VAGSYLDGIGVPACVGAA RAV ++ AL+ QVAR Sbjct 421 VAGSYLDGIGVPACVGAASRAVDGIVGALNPQVAR 455 >gi|342858452|ref|ZP_08715107.1| protoporphyrinogen oxidase [Mycobacterium colombiense CECT 3035] gi|342134156|gb|EGT87336.1| protoporphyrinogen oxidase [Mycobacterium colombiense CECT 3035] Length=458 Score = 619 bits (1596), Expect = 3e-175, Method: Compositional matrix adjust. Identities = 339/458 (75%), Positives = 382/458 (84%), Gaps = 6/458 (1%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 M+ SYCVVGGGISGLT+AYRLR A GDDA ITLF+P DRLGGVLRTE +GG PMD+GAE Sbjct 1 MSLPSYCVVGGGISGLTAAYRLRMAAGDDAAITLFDPGDRLGGVLRTEAVGGVPMDVGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPE+PALL EL LS RQ STGARPLIYS + L LP TVVGIPSSA S+AGLV Sbjct 61 AFVLRRPELPALLGELNLSGRQRVSTGARPLIYSLRELRALPAGTVVGIPSSAASVAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 D AT+ARI+AE +RP W+ G DPAVADLV +RFG+QVVARSVDPLLSGVYAGS+ATIGL Sbjct 121 DGATVARIEAEPSRPLAWEPGGDPAVADLVGERFGEQVVARSVDPLLSGVYAGSSATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RAAAP+VAAALDRGATS+TDAV +ALPP +G PVFG+L+GGYQVL+D L+ R R WVRA Sbjct 181 RAAAPTVAAALDRGATSLTDAVGRALPPATGAPVFGSLEGGYQVLIDELLARGRPRWVRA 240 Query 241 RVVQLER---GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSA 297 V +LER GW + D+TG W ADAVILAVPA + +RL+ GIAPR+ AAA ++ SASSA Sbjct 241 AVSRLERAGAGWTVVDDTGAGWAADAVILAVPAAQCSRLLAGIAPRSAAAAGRVTSASSA 300 Query 298 VVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPAL 357 V+ALAVPG TAFP CSGVLVA E AKAITLSSRKWG RGD LLRLSFGRFGD A Sbjct 301 VMALAVPGDTAFPDCSGVLVATGERLRAKAITLSSRKWGARGDAQLLRLSFGRFGDRVAA 360 Query 358 TASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLA 417 SDD+LL WA DL TVFG+A++PVDVR++RWI+AMPQYGPGHAD+VAE+RAGLPPT+A Sbjct 361 DTSDDELLTWALGDLATVFGLAIEPVDVRIQRWIDAMPQYGPGHADLVAEVRAGLPPTIA 420 Query 418 VAGSYLDGIGVPACVGAAGRAVTSVIEA---LDAQVAR 452 VAGSYLDGIGVPACVGAAGRAV VI A LDAQVAR Sbjct 421 VAGSYLDGIGVPACVGAAGRAVERVIRAIGDLDAQVAR 458 >gi|118618641|ref|YP_906973.1| protoporphyrinogen oxidase [Mycobacterium ulcerans Agy99] gi|118570751|gb|ABL05502.1| protoporphyrinogen oxidase HemY [Mycobacterium ulcerans Agy99] Length=455 Score = 618 bits (1593), Expect = 8e-175, Method: Compositional matrix adjust. Identities = 332/455 (73%), Positives = 380/455 (84%), Gaps = 3/455 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTP SYCVVGGGISGLT+A+RLR AVG+DA ITL +P+DRLGG+LRTE +GGQPMDLGAE Sbjct 1 MTPGSYCVVGGGISGLTAAFRLRLAVGEDALITLLDPSDRLGGILRTERVGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFV+RRPEMPALLAELGLS Q ++TGARPLIYS Q LHPLP TV+GIP+SA S+A LV Sbjct 61 AFVVRRPEMPALLAELGLSGLQRSTTGARPLIYSCQELHPLPTGTVMGIPASARSLADLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDAT+A+I+AE RP W+ G DPAVA+LVA+RFG+Q V RSVDPLL GVYAGSAATIG+ Sbjct 121 DDATIAQIEAEPDRPLHWRPGGDPAVAELVAERFGEQTVTRSVDPLLCGVYAGSAATIGV 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RAA P+VAAALDRGATS+T+AVRQ+LPP S GPVFGAL GGYQVL++ LV RS V WV+A Sbjct 181 RAAIPAVAAALDRGATSLTEAVRQSLPPASAGPVFGALTGGYQVLVEELVARSGVQWVQA 240 Query 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRLARL---VDGIAPRTHAAARQIVSASSA 297 V ++E GW L D+ G RW ADAVILA+PAPRL R+ VDG+ PR+ AAA ++ SASSA Sbjct 241 AVSKIEPGWALHDDAGRRWHADAVILAIPAPRLVRILDGVDGVDPRSVAAASRVRSASSA 300 Query 298 VVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPAL 357 VVALAVP T FP CSGVLVA E AKAITLSSRKWG +GDV LR+SFGRFGD+ A Sbjct 301 VVALAVPADTPFPQCSGVLVANGEPLRAKAITLSSRKWGIQGDVQQLRISFGRFGDDLAE 360 Query 358 TASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLA 417 SD QLL+WA DDL TVFGV VDPVD RV+RWIEAMP+YGPGH +VA++RAGLPPTLA Sbjct 361 RVSDHQLLSWARDDLATVFGVTVDPVDSRVQRWIEAMPRYGPGHGVLVAQVRAGLPPTLA 420 Query 418 VAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 VAGSYLDGIGVPACVGAA RAV V+ AL+ QVAR Sbjct 421 VAGSYLDGIGVPACVGAASRAVDGVVGALNPQVAR 455 >gi|240169728|ref|ZP_04748387.1| protoporphyrinogen oxidase [Mycobacterium kansasii ATCC 12478] Length=441 Score = 612 bits (1578), Expect = 4e-173, Method: Compositional matrix adjust. Identities = 330/441 (75%), Positives = 375/441 (86%), Gaps = 3/441 (0%) Query 9 VGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPE 68 +GGGISGLT+AYRLR A G D TIT+F+P DRLGG+LRTE +GGQPMD+GAEAFVLRRPE Sbjct 1 MGGGISGLTAAYRLRAAAGADGTITVFDPGDRLGGILRTEVVGGQPMDVGAEAFVLRRPE 60 Query 69 MPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARI 128 +PALLAELGL++RQ A+TG RP+IYS Q+LH LP T++GIP+SA S+AGLVDDAT+ARI Sbjct 61 VPALLAELGLAERQRATTGVRPMIYSGQQLHALPSGTMMGIPTSASSLAGLVDDATIARI 120 Query 129 DAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVA 188 +AE RPF+W+ GSDPAVA+LVADRFG+Q VARSVDPLL GVYAGSAATIGLRAAAPSVA Sbjct 121 EAEPGRPFSWRPGSDPAVAELVADRFGEQTVARSVDPLLCGVYAGSAATIGLRAAAPSVA 180 Query 189 AALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLER- 247 AALDRGA S+TDAVRQ LPP GPVFGAL+GGYQVL+D LV RSR++WVRA VV++ R Sbjct 181 AALDRGAASLTDAVRQGLPPAGDGPVFGALEGGYQVLVDELVARSRLNWVRAAVVEIGRT 240 Query 248 --GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPG 305 GW L DETGGRW ADAVILA+PAPRL LV+ IAPR+ AAR+I SASSAVVALAV Sbjct 241 GEGWELHDETGGRWHADAVILAIPAPRLVPLVEEIAPRSAGAARRIASASSAVVALAVSL 300 Query 306 GTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLL 365 T FP CSGVLVA E AKAITLSSRKWG RGD LLRLSFGRFGD+ A AS+ +LL Sbjct 301 DTPFPPCSGVLVASGERLRAKAITLSSRKWGPRGDTQLLRLSFGRFGDDLAERASEKELL 360 Query 366 AWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDG 425 AWA DDL TVFG+AV P+D RV+RW+EAMPQYGPGHAD+VAE+RAGLP LAVAGSYLDG Sbjct 361 AWALDDLATVFGLAVHPIDFRVQRWVEAMPQYGPGHADLVAEVRAGLPAGLAVAGSYLDG 420 Query 426 IGVPACVGAAGRAVTSVIEAL 446 IGVPACV AA AVT ++EAL Sbjct 421 IGVPACVAAADLAVTGIVEAL 441 >gi|41408896|ref|NP_961732.1| protoporphyrinogen oxidase [Mycobacterium avium subsp. paratuberculosis K-10] gi|41397255|gb|AAS05115.1| HemY' [Mycobacterium avium subsp. paratuberculosis K-10] gi|336458823|gb|EGO37780.1| protoporphyrinogen oxidase [Mycobacterium avium subsp. paratuberculosis S397] Length=451 Score = 572 bits (1475), Expect = 4e-161, Method: Compositional matrix adjust. Identities = 332/454 (74%), Positives = 374/454 (83%), Gaps = 7/454 (1%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MT RSYCVVGGGISGLT+AYRLR A GDDA ITL +PA +LGG+LRTE +GG PMDLGAE Sbjct 1 MTARSYCVVGGGISGLTAAYRLRVAAGDDAVITLLDPAPQLGGILRTEPVGGVPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPE+PALL+E+ L+ RQ STGARPLIYS+ RLHPLP TVVGIPSSA SMA LV Sbjct 61 AFVLRRPELPALLSEVNLTGRQRVSTGARPLIYSRGRLHPLPTGTVVGIPSSAASMARLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 D+ATLARIDAE RP W+ GSDPAVADLV DRFG+QVV+RSVDPLLSGVYAGSAATIGL Sbjct 121 DEATLARIDAEPRRPLHWRPGSDPAVADLVGDRFGEQVVSRSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RAAAP+VAAALDRGA S+TDAVR+ALPP +G PVFGALDGGY+VL+D LV R+R VRA Sbjct 181 RAAAPTVAAALDRGAASLTDAVRRALPPATGAPVFGALDGGYRVLVDELVARARPRRVRA 240 Query 241 RVVQLE---RGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSA 297 +LE GW + D+ G R ADAVILAVPA +ARL+ GIAPR+ AAA ++V+ASS Sbjct 241 AAARLEPAGPGWAVVDDAGARRHADAVILAVPAREVARLLAGIAPRSAAAAGRVVAASSV 300 Query 298 VVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPAL 357 V+ALAVPG TAFP CSGVLVA E AKAITLSS+KWG R DV LLRLSFGRFGD+ A Sbjct 301 VLALAVPGDTAFPDCSGVLVATGERLRAKAITLSSKKWGTRADVQLLRLSFGRFGDQVAA 360 Query 358 TASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLA 417 D++L WA DL VFG+ V PVDVRV+RW++AMPQYGPGHA++V ELRAGLPPTLA Sbjct 361 RTPDEELRGWALADLAAVFGLDVRPVDVRVQRWLDAMPQYGPGHAELVGELRAGLPPTLA 420 Query 418 VAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVA 451 VAG YLDGIGVPACVGAAGRAV EAL A+VA Sbjct 421 VAGGYLDGIGVPACVGAAGRAV----EALQAEVA 450 >gi|254365339|ref|ZP_04981384.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis str. Haarlem] gi|134150852|gb|EBA42897.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis str. Haarlem] Length=388 Score = 569 bits (1466), Expect = 3e-160, Method: Compositional matrix adjust. Identities = 299/299 (100%), Positives = 299/299 (100%), Gaps = 0/299 (0%) Query 154 FGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGP 213 FGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGP Sbjct 90 FGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGP 149 Query 214 VFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRL 273 VFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRL Sbjct 150 VFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRL 209 Query 274 ARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSR 333 ARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSR Sbjct 210 ARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSR 269 Query 334 KWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEA 393 KWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEA Sbjct 270 KWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEA 329 Query 394 MPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 MPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR Sbjct 330 MPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 388 >gi|289758805|ref|ZP_06518183.1| LOW QUALITY PROTEIN: protoporphyrinogen oxidase [Mycobacterium tuberculosis T85] gi|289714369|gb|EFD78381.1| LOW QUALITY PROTEIN: protoporphyrinogen oxidase [Mycobacterium tuberculosis T85] Length=288 Score = 547 bits (1410), Expect = 1e-153, Method: Compositional matrix adjust. Identities = 286/288 (99%), Positives = 287/288 (99%), Gaps = 0/288 (0%) Query 165 PLLSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQV 224 P +SGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQV Sbjct 1 PAVSGVYAGSAATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQV 60 Query 225 LLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRT 284 LLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRT Sbjct 61 LLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRT 120 Query 285 HAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALL 344 HAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALL Sbjct 121 HAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALL 180 Query 345 RLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADV 404 RLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADV Sbjct 181 RLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADV 240 Query 405 VAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 VAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR Sbjct 241 VAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 288 >gi|118467902|ref|YP_887112.1| protoporphyrinogen oxidase [Mycobacterium smegmatis str. MC2 155] gi|118169189|gb|ABK70085.1| protoporphyrinogen oxidase [Mycobacterium smegmatis str. MC2 155] Length=453 Score = 536 bits (1380), Expect = 4e-150, Method: Compositional matrix adjust. Identities = 301/449 (68%), Positives = 363/449 (81%), Gaps = 6/449 (1%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MT R +CVVGGGISGL +AYRLR+A G A ITL +PADRLGG+LRTE +GGQ +D+GAE Sbjct 1 MTMR-FCVVGGGISGLVAAYRLRRAAGPHADITLLDPADRLGGILRTERVGGQWLDVGAE 59 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFV RRPEMPALLAELGL+ RQ+A++GARPLIYS RLHPLP T+ GIP+ A S+ GLV Sbjct 60 AFVARRPEMPALLAELGLAGRQIATSGARPLIYSGARLHPLPQGTLQGIPAQASSLLGLV 119 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDAT+A+I E ARPF W+ GSDP+VAD+V DRFG QVV RSVDPLL+GVYAGS+ATIGL Sbjct 120 DDATVAQIIDERARPFAWRPGSDPSVADVVGDRFGMQVVYRSVDPLLTGVYAGSSATIGL 179 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 R+A P++AAALDRGA S+TDAVR ALPP G VFGALDGGY+VLL+ L RR+ V W + Sbjct 180 RSAVPTLAAALDRGAPSLTDAVRDALPPPVTGSVFGALDGGYRVLLEELQRRAAVRWAQV 239 Query 241 RVVQLER---GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSA 297 V+++R GW++ D+ G W AD V+LAVPAP L L++ +APRT AAAR+I AS+A Sbjct 240 TAVRVDRDANGWLVFDDEGTNWNADGVVLAVPAPALPALIEHVAPRTAAAARRIRVASAA 299 Query 298 VVALAVPGGTAFPHCSGVLVAGDE--SPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEP 355 VVALA+PGGT P SGVLVA E S +AKA+TLSSRKWG+RG+V LLRLSFGR+GD+ Sbjct 300 VVALALPGGTPIPQQSGVLVATGEAGSLNAKAVTLSSRKWGRRGNVELLRLSFGRYGDDL 359 Query 356 ALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPT 415 A + D+ LLAW+ DL T+FG+ VDPVD ++RWI+AMPQYGPGH D+VAELRAGLPP Sbjct 360 ARSTGDEDLLAWSTRDLNTLFGITVDPVDWHIQRWIDAMPQYGPGHLDLVAELRAGLPPN 419 Query 416 LAVAGSYLDGIGVPACVGAAGRAVTSVIE 444 LAV GSYLDGIGVPACVGAA RA ++++ Sbjct 420 LAVTGSYLDGIGVPACVGAATRAALTLVK 448 >gi|108799180|ref|YP_639377.1| protoporphyrinogen oxidase [Mycobacterium sp. MCS] gi|119868295|ref|YP_938247.1| protoporphyrinogen oxidase [Mycobacterium sp. KMS] gi|108769599|gb|ABG08321.1| protoporphyrinogen oxidase [Mycobacterium sp. MCS] gi|119694384|gb|ABL91457.1| protoporphyrinogen oxidase [Mycobacterium sp. KMS] Length=451 Score = 527 bits (1357), Expect = 2e-147, Method: Compositional matrix adjust. Identities = 310/441 (71%), Positives = 360/441 (82%), Gaps = 3/441 (0%) Query 5 SYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVL 64 +Y VVGGGISGL +AYRLR G DATITLF+PADRLGGVLRTE +GGQ +D+GAEAFV Sbjct 4 TYAVVGGGISGLVAAYRLRVTAGPDATITLFDPADRLGGVLRTERVGGQLLDVGAEAFVA 63 Query 65 RRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDAT 124 RRPE+PALLAELGL+DRQ+ +TGARPLIYSQ RLHP+P T+ GIPS A ++AGLVDDAT Sbjct 64 RRPEVPALLAELGLADRQIGTTGARPLIYSQGRLHPMPQGTLQGIPSGAATLAGLVDDAT 123 Query 125 LARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAA 184 +ARI E RP W+ G+DP VADLV DRFG+QVV+RSVDPLL GVYAGSAATIGLRAAA Sbjct 124 IARIADEPTRPLRWRPGADPTVADLVVDRFGEQVVSRSVDPLLGGVYAGSAATIGLRAAA 183 Query 185 PSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA---R 241 P++AAALDRGA ++TDAVR+ALPP + G VFGA+DGGY VLLD L R+R+HW + R Sbjct 184 PTLAAALDRGARNLTDAVREALPPPAPGSVFGAVDGGYAVLLDALRHRARIHWAQVGVER 243 Query 242 VVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVAL 301 V + RG + D+ G RW ADAV+LAVPAPRL RLVD IAPRT AAAR+I AS+AVVAL Sbjct 244 VDLVGRGVEIVDDEGNRWPADAVVLAVPAPRLPRLVDHIAPRTAAAARRIPVASAAVVAL 303 Query 302 AVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASD 361 A+PGGT P SGVLVA E KAITLSSRKWG+RG+V LLRLS+GRFGD+ A + D Sbjct 304 ALPGGTPLPQQSGVLVATGERLRTKAITLSSRKWGRRGNVELLRLSYGRFGDDLARSTGD 363 Query 362 DQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGS 421 + LLAWAA DL TVFG+ +PVD V+RWI+AMPQYGPGHAD+VAELRAGLP +AVAG Sbjct 364 EDLLAWAAADLGTVFGIDTEPVDALVQRWIDAMPQYGPGHADLVAELRAGLPRGVAVAGG 423 Query 422 YLDGIGVPACVGAAGRAVTSV 442 YLDGIGVPACV +A RAV S+ Sbjct 424 YLDGIGVPACVASASRAVASL 444 >gi|126434788|ref|YP_001070479.1| protoporphyrinogen oxidase [Mycobacterium sp. JLS] gi|126234588|gb|ABN97988.1| protoporphyrinogen oxidase [Mycobacterium sp. JLS] Length=451 Score = 526 bits (1354), Expect = 4e-147, Method: Compositional matrix adjust. Identities = 310/441 (71%), Positives = 361/441 (82%), Gaps = 3/441 (0%) Query 5 SYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVL 64 +Y VVGGGISGL +AYRLR G DATITLF+PADRLGGVLRTE +GGQ +D+GAEAFV Sbjct 4 TYAVVGGGISGLVAAYRLRVTAGPDATITLFDPADRLGGVLRTERVGGQLLDVGAEAFVA 63 Query 65 RRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDAT 124 RRPE+PALLAELGL+DRQ+ +TGARPLIYSQ RLHP+P T+ GIPS A ++AGLVDDAT Sbjct 64 RRPEVPALLAELGLADRQIGTTGARPLIYSQGRLHPMPQGTLQGIPSGAATLAGLVDDAT 123 Query 125 LARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAA 184 +ARI E RP W+ G+DP VADLV DRFG+QVV+RSVDPLL GVYAGSAATIGLRAAA Sbjct 124 IARIADEPTRPLRWRPGADPTVADLVVDRFGEQVVSRSVDPLLGGVYAGSAATIGLRAAA 183 Query 185 PSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQ 244 P++AAALDRGA ++TDAV +ALPP + G VFGA+DGGY VLLD L R+R+HW + V + Sbjct 184 PTLAAALDRGARNLTDAVGEALPPPAPGSVFGAVDGGYAVLLDALRHRARIHWAQVGVER 243 Query 245 LE---RGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVAL 301 L+ RG + D+ G RW ADAV+LAVPAPRL RLVD IAPRT AAAR+I AS+AVVAL Sbjct 244 LDLVGRGVEIVDDEGNRWPADAVVLAVPAPRLPRLVDHIAPRTAAAARRIPVASAAVVAL 303 Query 302 AVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASD 361 A+PGGT P SGVLVA E AKAITLSSRKWG+RG+V LLRLS+GRFGD+ A + D Sbjct 304 ALPGGTPLPQQSGVLVATGERLRAKAITLSSRKWGRRGNVELLRLSYGRFGDDLARSTGD 363 Query 362 DQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGS 421 + LLAWAA DL TVFG+ +PVD V+RWI+AMPQYGPGHAD+VAELRAGLP +AVAG Sbjct 364 EDLLAWAAADLGTVFGIDTEPVDALVQRWIDAMPQYGPGHADLVAELRAGLPRGVAVAGG 423 Query 422 YLDGIGVPACVGAAGRAVTSV 442 YLDGIGVPACV +A RAV S+ Sbjct 424 YLDGIGVPACVASASRAVASL 444 >gi|333991063|ref|YP_004523677.1| protoporphyrinogen oxidase HemY [Mycobacterium sp. JDM601] gi|333487031|gb|AEF36423.1| protoporphyrinogen oxidase HemY [Mycobacterium sp. JDM601] Length=453 Score = 519 bits (1336), Expect = 5e-145, Method: Compositional matrix adjust. Identities = 286/434 (66%), Positives = 340/434 (79%), Gaps = 7/434 (1%) Query 5 SYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVL 64 +YCVVGGGISGL +AYRLR +G TIT+F+PADRLGGVLRTE +GG +D+GAEAFV Sbjct 4 TYCVVGGGISGLAAAYRLRATLGAAPTITVFDPADRLGGVLRTETLGGIGVDVGAEAFVA 63 Query 65 RRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDAT 124 RRPE+PALL+ELGL+DR+ +TG RPL+Y+++RLHPLPP T+ GIPSS G+MAGLVD+ T Sbjct 64 RRPEVPALLSELGLADRERTTTGVRPLLYNRRRLHPLPPGTLSGIPSSPGAMAGLVDEET 123 Query 125 LARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAA 184 +ARI E R T++ GSDPA+ LV DRFG+QVVA SVDPL+ GVYAGSAAT+GLR+A Sbjct 124 IARIAGEPNRRLTFEPGSDPALGTLVGDRFGEQVVAASVDPLIGGVYAGSAATVGLRSAV 183 Query 185 PSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQ 244 P +AAALD GA S+T AV +ALP +G PVFGA+ GGYQVL+D LVRRS + WV+A V Q Sbjct 184 PGLAAALDAGAPSLTAAVARALPRATGTPVFGAIAGGYQVLIDALVRRSGLRWVQAAVTQ 243 Query 245 LE---RGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVAL 301 ++ GW+LRD GG AD V++AVPA LARL G APRT AAA IVSASS VVAL Sbjct 244 IDPVADGWLLRDAAGGFHHADRVVMAVPANTLARLATGFAPRTAAAASGIVSASSVVVAL 303 Query 302 AVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQ---RGDVALLRLSFGRFGDEPALT 358 AVP G AFP SGVLVA E HAKA+TL+SRKWG G V LLRLSFGRFGD Sbjct 304 AVPAGAAFPDNSGVLVATGERLHAKALTLTSRKWGNWGYGGKVELLRLSFGRFGDA-RTH 362 Query 359 ASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAV 418 A++ +L+ WA DL T+FGV VDPV+VRV+RW AMPQY PGHA +V ELRAGLPPT+AV Sbjct 363 ATEAELVGWAVQDLETLFGVMVDPVEVRVQRWPAAMPQYRPGHAALVGELRAGLPPTVAV 422 Query 419 AGSYLDGIGVPACV 432 AG+YLDGIGVPAC+ Sbjct 423 AGNYLDGIGVPACI 436 >gi|120403472|ref|YP_953301.1| protoporphyrinogen oxidase [Mycobacterium vanbaalenii PYR-1] gi|119956290|gb|ABM13295.1| protoporphyrinogen oxidase [Mycobacterium vanbaalenii PYR-1] Length=453 Score = 509 bits (1310), Expect = 5e-142, Method: Compositional matrix adjust. Identities = 292/431 (68%), Positives = 343/431 (80%), Gaps = 3/431 (0%) Query 2 TPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEA 61 P YCVVGGGISGL +AYRLR A G DA+ITL +PADRLGGVLRTE IGGQ +D+GAEA Sbjct 5 VPARYCVVGGGISGLVAAYRLRVAAGPDASITLLDPADRLGGVLRTERIGGQLLDVGAEA 64 Query 62 FVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVD 121 FV RRPE+PALL ELGLS RQ+ +GARPLIYS+ RLHPLP TV GIPS ++AGLVD Sbjct 65 FVARRPEVPALLGELGLSGRQIVPSGARPLIYSEGRLHPLPKDTVQGIPSRPEALAGLVD 124 Query 122 DATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLR 181 DAT+ + E RPF+W G+DP+VA+LV DRFG+QVV RSVDPLLSGVYAGSAATIG+R Sbjct 125 DATIRWMLDEPRRPFSWCQGADPSVAELVGDRFGEQVVIRSVDPLLSGVYAGSAATIGIR 184 Query 182 AAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRAR 241 A AP+VAAALD GA S+T+AV +ALPP G VFGA+DGGYQVL+D LVRRS + W + Sbjct 185 AGAPTVAAALDGGARSLTEAVTRALPPPQAGAVFGAIDGGYQVLVDELVRRSWLEWAQVS 244 Query 242 VVQL---ERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAV 298 V + RGW + D+ G RW ADAV+LAVPAPRL LV IAPRT AAAR+I AS+AV Sbjct 245 VRSVGRGARGWEVLDDEGTRWPADAVVLAVPAPRLPALVADIAPRTAAAARRIPVASAAV 304 Query 299 VALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALT 358 VALA+PGGT P SGVLVAG AKA+TLSS+KWG+R +V ++RLS+GRFGD+ A + Sbjct 305 VALALPGGTPLPEQSGVLVAGQGRLRAKAVTLSSKKWGRRANVEMVRLSYGRFGDDLARS 364 Query 359 ASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAV 418 D+ LLAWAA DL +FG++VDPVD RV RWI+A+PQYGPGHA +VAELRAGLP LAV Sbjct 365 TGDEDLLAWAAQDLSVLFGISVDPVDSRVVRWIDALPQYGPGHAALVAELRAGLPGGLAV 424 Query 419 AGSYLDGIGVP 429 AG+YLDGIGVP Sbjct 425 AGAYLDGIGVP 435 >gi|289746477|ref|ZP_06505855.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis 02_1987] gi|289687005|gb|EFD54493.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis 02_1987] Length=266 Score = 508 bits (1308), Expect = 8e-142, Method: Compositional matrix adjust. Identities = 264/266 (99%), Positives = 265/266 (99%), Gaps = 0/266 (0%) Query 187 VAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLE 246 +AA LDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLE Sbjct 1 MAAPLDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLE 60 Query 247 RGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGG 306 RGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGG Sbjct 61 RGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGG 120 Query 307 TAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLA 366 TAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLA Sbjct 121 TAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLA 180 Query 367 WAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGI 426 WAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGI Sbjct 181 WAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGI 240 Query 427 GVPACVGAAGRAVTSVIEALDAQVAR 452 GVPACVGAAGRAVTSVIEALDAQVAR Sbjct 241 GVPACVGAAGRAVTSVIEALDAQVAR 266 >gi|315444830|ref|YP_004077709.1| protoporphyrinogen oxidase [Mycobacterium sp. Spyr1] gi|315263133|gb|ADT99874.1| protoporphyrinogen oxidase [Mycobacterium sp. Spyr1] Length=454 Score = 506 bits (1303), Expect = 3e-141, Method: Compositional matrix adjust. Identities = 288/427 (68%), Positives = 338/427 (80%), Gaps = 3/427 (0%) Query 6 YCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLR 65 YCVVGGGISGL +AYRLR A G DA IT+ +PADRLGG+LRTE IGGQ +D+GAEAFV R Sbjct 7 YCVVGGGISGLVAAYRLRVAAGPDAVITVLDPADRLGGILRTERIGGQAIDVGAEAFVAR 66 Query 66 RPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATL 125 RPE+PALL ELGLS RQ+ +TGARPLIYS+ RLH LP TV GIPS +++GLVDDAT+ Sbjct 67 RPEVPALLGELGLSGRQITTTGARPLIYSEGRLHQLPADTVNGIPSRPSALSGLVDDATV 126 Query 126 ARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAP 185 + E RP W+ G+DP VA+LV +RFG+QVV RSVDPLL+GVYAGSAATIG+RAAAP Sbjct 127 RWMLDEPRRPLVWRSGADPTVAELVGERFGEQVVVRSVDPLLAGVYAGSAATIGMRAAAP 186 Query 186 SVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHW--VRARVV 243 +VAAALD GA S+T+AV ALPP G VFGA+DGGYQVLLD LVRRS + W V AR V Sbjct 187 TVAAALDNGARSLTEAVVAALPPARAGSVFGAIDGGYQVLLDELVRRSGLQWAQVAARGV 246 Query 244 QLER-GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALA 302 R GW + D+ GG W ADAV+LAVPAPRL L+ +AP + AR+I AS+AVVALA Sbjct 247 HPVRAGWEVVDDEGGHWPADAVVLAVPAPRLPALLADLAPHSADIARRIPVASAAVVALA 306 Query 303 VPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDD 362 +PGGT P SGVLVAG H KA+TLSSRKWG+RG +LRLS+GRFGD+ A + DD Sbjct 307 LPGGTPLPEQSGVLVAGRGPLHTKAVTLSSRKWGRRGSAEMLRLSYGRFGDDLARSTGDD 366 Query 363 QLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSY 422 +LLAWA +DL T+FG+AV+PVD RV RWI+AMPQYGPGHAD VA+LRAGLP LAVAG+Y Sbjct 367 ELLAWADEDLATLFGIAVEPVDARVVRWIDAMPQYGPGHADRVADLRAGLPRGLAVAGAY 426 Query 423 LDGIGVP 429 LDGIGVP Sbjct 427 LDGIGVP 433 >gi|145224499|ref|YP_001135177.1| protoporphyrinogen oxidase [Mycobacterium gilvum PYR-GCK] gi|145216985|gb|ABP46389.1| protoporphyrinogen oxidase [Mycobacterium gilvum PYR-GCK] Length=454 Score = 505 bits (1301), Expect = 6e-141, Method: Compositional matrix adjust. Identities = 288/427 (68%), Positives = 338/427 (80%), Gaps = 3/427 (0%) Query 6 YCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLR 65 YCVVGGGISGL +AYRLR A G DA IT+ +PADRLGG+LRTE IGGQ +D+GAEAFV R Sbjct 7 YCVVGGGISGLVAAYRLRVAAGPDAVITVLDPADRLGGILRTERIGGQAIDVGAEAFVAR 66 Query 66 RPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATL 125 RPE+PALL ELGLS RQ+ +TGARPLIYS+ RLH LP TV GIPS +++GLVDDAT+ Sbjct 67 RPEVPALLGELGLSGRQITTTGARPLIYSEGRLHQLPTDTVNGIPSRPSALSGLVDDATV 126 Query 126 ARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAP 185 + E RP W+ G+DP VA+LV +RFG+QVV RSVDPLL+GVYAGSAATIG+RAAAP Sbjct 127 RWMLDEPRRPLVWRSGADPTVAELVGERFGEQVVVRSVDPLLAGVYAGSAATIGMRAAAP 186 Query 186 SVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHW--VRARVV 243 +VAAALD GA S+T+AV ALPP G VFGA+DGGYQVLLD LVRRS + W V AR V Sbjct 187 TVAAALDNGARSLTEAVVAALPPPRAGSVFGAIDGGYQVLLDELVRRSGLQWAQVAARGV 246 Query 244 QLER-GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALA 302 R GW + D+ GG W ADAV+LAVPAPRL L+ +AP + AR+I AS+AVVALA Sbjct 247 HPVRAGWEVVDDEGGHWPADAVVLAVPAPRLPALLAELAPHSADIARRIPVASAAVVALA 306 Query 303 VPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDD 362 +PGGT P SGVLVAG H KA+TLSSRKWG+RG +LRLS+GRFGD+ A + DD Sbjct 307 LPGGTPLPEQSGVLVAGRGPLHTKAVTLSSRKWGRRGSAEMLRLSYGRFGDDLARSTGDD 366 Query 363 QLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSY 422 +LLAWA +DL T+FG+AV+PVD RV RWI+AMPQYGPGHAD VA+LRAGLP LAVAG+Y Sbjct 367 ELLAWADEDLATLFGIAVEPVDARVVRWIDAMPQYGPGHADRVADLRAGLPRGLAVAGAY 426 Query 423 LDGIGVP 429 LDGIGVP Sbjct 427 LDGIGVP 433 >gi|289746478|ref|ZP_06505856.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis 02_1987] gi|289687006|gb|EFD54494.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis 02_1987] Length=344 Score = 494 bits (1271), Expect = 2e-137, Method: Compositional matrix adjust. Identities = 265/273 (98%), Positives = 266/273 (98%), Gaps = 0/273 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL Sbjct 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA Sbjct 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRA 240 Query 241 RVVQLERGWVLRDETGGRWQADAVILAVPAPRL 273 RVVQLERGWVLRDET GRW DA IL P PR+ Sbjct 241 RVVQLERGWVLRDETDGRWVGDAGILRAPGPRM 273 >gi|307080778|ref|ZP_07489948.1| hypothetical protein TMKG_03106 [Mycobacterium tuberculosis SUMu011] gi|308361492|gb|EFP50343.1| hypothetical protein TMKG_03106 [Mycobacterium tuberculosis SUMu011] Length=251 Score = 486 bits (1251), Expect = 3e-135, Method: Compositional matrix adjust. Identities = 251/251 (100%), Positives = 251/251 (100%), Gaps = 0/251 (0%) Query 202 VRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQA 261 VRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQA Sbjct 1 VRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQA 60 Query 262 DAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDE 321 DAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDE Sbjct 61 DAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDE 120 Query 322 SPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVD 381 SPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVD Sbjct 121 SPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVD 180 Query 382 PVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTS 441 PVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTS Sbjct 181 PVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTS 240 Query 442 VIEALDAQVAR 452 VIEALDAQVAR Sbjct 241 VIEALDAQVAR 251 >gi|323718737|gb|EGB27898.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis CDC1551A] Length=239 Score = 462 bits (1190), Expect = 4e-128, Method: Compositional matrix adjust. Identities = 238/239 (99%), Positives = 239/239 (100%), Gaps = 0/239 (0%) Query 214 VFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRL 273 +FGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRL Sbjct 1 MFGALDGGYQVLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRL 60 Query 274 ARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSR 333 ARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSR Sbjct 61 ARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSR 120 Query 334 KWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEA 393 KWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEA Sbjct 121 KWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEA 180 Query 394 MPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 MPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR Sbjct 181 MPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 239 >gi|308371093|ref|ZP_07423804.2| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis SUMu003] gi|308329865|gb|EFP18716.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis SUMu003] Length=229 Score = 442 bits (1137), Expect = 6e-122, Method: Compositional matrix adjust. Identities = 228/229 (99%), Positives = 229/229 (100%), Gaps = 0/229 (0%) Query 224 VLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPR 283 +LLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPR Sbjct 1 MLLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPR 60 Query 284 THAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVAL 343 THAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVAL Sbjct 61 THAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVAL 120 Query 344 LRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHAD 403 LRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHAD Sbjct 121 LRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHAD 180 Query 404 VVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 VVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR Sbjct 181 VVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 229 >gi|307085370|ref|ZP_07494483.1| hypothetical protein TMLG_02390 [Mycobacterium tuberculosis SUMu012] gi|308365099|gb|EFP53950.1| hypothetical protein TMLG_02390 [Mycobacterium tuberculosis SUMu012] Length=228 Score = 441 bits (1133), Expect = 1e-121, Method: Compositional matrix adjust. Identities = 227/228 (99%), Positives = 228/228 (100%), Gaps = 0/228 (0%) Query 225 LLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRT 284 +LDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRT Sbjct 1 MLDGLVRRSRVHWVRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRT 60 Query 285 HAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALL 344 HAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALL Sbjct 61 HAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALL 120 Query 345 RLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADV 404 RLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADV Sbjct 121 RLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADV 180 Query 405 VAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 VAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR Sbjct 181 VAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 228 >gi|308371094|ref|ZP_07667088.1| hypothetical protein TMCG_01924 [Mycobacterium tuberculosis SUMu003] gi|308329840|gb|EFP18691.1| hypothetical protein TMCG_01924 [Mycobacterium tuberculosis SUMu003] Length=226 Score = 437 bits (1124), Expect = 2e-120, Method: Compositional matrix adjust. Identities = 226/226 (100%), Positives = 226/226 (100%), Gaps = 0/226 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL Sbjct 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLL 226 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLL Sbjct 181 RAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLL 226 >gi|169630068|ref|YP_001703717.1| protoporphyrinogen oxidase [Mycobacterium abscessus ATCC 19977] gi|169242035|emb|CAM63063.1| Protoporphyrinogen oxidase HemY' [Mycobacterium abscessus] Length=458 Score = 435 bits (1118), Expect = 9e-120, Method: Compositional matrix adjust. Identities = 258/440 (59%), Positives = 315/440 (72%), Gaps = 9/440 (2%) Query 1 MTPR-----SYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPM 55 MTP+ S +VGGGISGLT+AYRLR+ +GDDA I+L++PA +LGG+LRT +G + Sbjct 1 MTPQPSGSPSIAIVGGGISGLTAAYRLRRELGDDARISLYDPAGQLGGILRTITLGEHRI 60 Query 56 DLGAEAFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGS 115 D+GAEAF+ RRPE+ LL ELGL+DR L +TGARPLIY+ LHPLP +TV GIP+SA S Sbjct 61 DIGAEAFITRRPEVLDLLDELGLADRTLDTTGARPLIYAGGGLHPLPARTVNGIPASASS 120 Query 116 MAGLVDDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSA 175 + GLVD+ T+ARID+E R W VG++P VADLVA RFG QVVAR VDPLL GVYAGSA Sbjct 121 VVGLVDEETVARIDSEPQRDMHWTVGAEPTVADLVALRFGPQVVARLVDPLLGGVYAGSA 180 Query 176 ATIGLRAAAPSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRV 235 AT GLR AAP +A ALD GA S+ A RQALPP S +FGA+DGGY VL++ L R+R Sbjct 181 ATTGLRTAAPGIARALDEGAGSLLAAARQALPPISDSGIFGAVDGGYAVLVEELWSRARA 240 Query 236 HWVRARVVQLER---GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIV 292 V+ V +ER GW + E G DAVI+AVPAPR A +++ +AP + AAAR I Sbjct 241 EHVQVAVTGIERDGAGWAVTGEGGLTDAVDAVIVAVPAPRAAAILEAVAPESAAAARTIP 300 Query 293 SASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRG-DVALLRLSFGRF 351 ASS VVAL +PG P SGVLVA E+ H KAIT S+ KWG RG ++RLS+GRF Sbjct 301 VASSVVVALTLPGDAPIPANSGVLVASGEALHTKAITFSTSKWGLRGRSTQVVRLSYGRF 360 Query 352 GDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAG 411 GD A +D+QL WA DL V G + PV+ V RWI+AMPQYGPGHA+VV +R+G Sbjct 361 GDTVARATTDEQLRHWAVADLEAVLGAGIVPVNSAVARWIDAMPQYGPGHAEVVDAIRSG 420 Query 412 LPPTLAVAGSYLDGIGVPAC 431 LP +AVAGSYLDGIGVPAC Sbjct 421 LPSGIAVAGSYLDGIGVPAC 440 >gi|289444219|ref|ZP_06433963.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis T46] gi|289417138|gb|EFD14378.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis T46] Length=215 Score = 414 bits (1065), Expect = 1e-113, Method: Compositional matrix adjust. Identities = 214/215 (99%), Positives = 215/215 (100%), Gaps = 0/215 (0%) Query 238 VRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSA 297 +RARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSA Sbjct 1 MRARVVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSA 60 Query 298 VVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPAL 357 VVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPAL Sbjct 61 VVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPAL 120 Query 358 TASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLA 417 TASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLA Sbjct 121 TASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLA 180 Query 418 VAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 VAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR Sbjct 181 VAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 215 >gi|323718672|gb|EGB27834.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis CDC1551A] Length=207 Score = 400 bits (1027), Expect = 3e-109, Method: Compositional matrix adjust. Identities = 207/207 (100%), Positives = 207/207 (100%), Gaps = 0/207 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL Sbjct 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGATSVTDAVRQALP 207 RAAAPSVAAALDRGATSVTDAVRQALP Sbjct 181 RAAAPSVAAALDRGATSVTDAVRQALP 207 >gi|226366253|ref|YP_002784036.1| protoporphyrinogen oxidase [Rhodococcus opacus B4] gi|226244743|dbj|BAH55091.1| protoporphyrinogen oxidase [Rhodococcus opacus B4] Length=453 Score = 398 bits (1022), Expect = 1e-108, Method: Compositional matrix adjust. Identities = 246/439 (57%), Positives = 297/439 (68%), Gaps = 19/439 (4%) Query 5 SYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVL 64 + VVGGGISGL +AYRLRQ +G A I + + A RLGG LRT + G+P+D+GAEAF+ Sbjct 7 NVLVVGGGISGLVAAYRLRQRLGAGARIVVADGAQRLGGKLRTVDLAGEPVDVGAEAFIA 66 Query 65 RRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDAT 124 RRPE+PALL ELGL+D+ + G RPLI+S+ LHPLP T++GIP+ A S+ GLVDD T Sbjct 67 RRPELPALLGELGLADQLVHPAGLRPLIWSEDALHPLPSNTLMGIPADADSLRGLVDDRT 126 Query 125 LARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAA 184 LAR+ E A P W G+D AV LV DRFG QVV RSVDPLL GVY+G A TIG+RAA Sbjct 127 LARVAGERAVPLDWTPGADVAVGALVGDRFGAQVVQRSVDPLLGGVYSGLADTIGVRAAV 186 Query 185 PSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQ 244 P++AAALDRGATS++ AV +ALPP + GPVFGAL GY VLL L + V R+ Sbjct 187 PTLAAALDRGATSLSAAVAEALPPPAAGPVFGALRDGYGVLLRALTDAAGAEIVHERIRD 246 Query 245 LERGWVLRDETGGRWQA------DAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAV 298 L R G W A D V+LAVPAP+LA L+ GIAPR AAA I ASSAV Sbjct 247 LGR-------DGESWSADPVGRVDGVVLAVPAPQLAELLAGIAPRASAAAADIPLASSAV 299 Query 299 VALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQ--RGDVALLRLSFGRFGDEPA 356 VALA+P GT P SG+LVA D S AKA TLSSRKW +V L+R SFGRFGD Sbjct 300 VALALPAGTDVPQNSGILVATDTSLGAKAFTLSSRKWPHLAEREVTLVRASFGRFGDAAV 359 Query 357 LTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELR---AGLP 413 + A DD+L+A A DL TV GVA +PV V+RW +PQYGPGH + VAE+ AGL Sbjct 360 VDAPDDELIAAARRDLATVTGVAAEPVAAHVQRWHGGLPQYGPGHLERVAEIEQEVAGL- 418 Query 414 PTLAVAGSYLDGIGVPACV 432 + V+G+ L G+GVPACV Sbjct 419 DGVEVSGALLRGVGVPACV 437 >gi|111023817|ref|YP_706789.1| protoporphyrinogen oxidase [Rhodococcus jostii RHA1] gi|110823347|gb|ABG98631.1| protoporphyrinogen oxidase [Rhodococcus jostii RHA1] Length=453 Score = 380 bits (977), Expect = 2e-103, Method: Compositional matrix adjust. Identities = 247/436 (57%), Positives = 297/436 (69%), Gaps = 13/436 (2%) Query 5 SYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVL 64 + VVGGGISGL +AYRLRQ +G DA I L + A+RLGG LRT + G+P+D+GAEAF+ Sbjct 7 NVLVVGGGISGLVAAYRLRQRLGADARIILADGAERLGGKLRTVDLAGEPVDVGAEAFIA 66 Query 65 RRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDAT 124 RRPE+PALL ELGLSD+ + G RPLI+S+ LHPLP T++GIP+ S+ GLVDD T Sbjct 67 RRPELPALLGELGLSDQLVYPAGLRPLIWSEDALHPLPADTLMGIPAEGNSLRGLVDDRT 126 Query 125 LARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAA 184 LAR+ E PF W G+D AV LV DRFG QVV RSVDPLL GVY+G A TIG+RAA Sbjct 127 LARMAGERTVPFDWTPGADVAVGALVGDRFGAQVVQRSVDPLLGGVYSGLADTIGVRAAL 186 Query 185 PSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQ 244 P++AAALDRGATS++ AV ALP + GPVFGAL GY VLL L + V V R+ Sbjct 187 PTLAAALDRGATSLSAAVADALPAPTPGPVFGALRDGYGVLLRALTEAASVEIVHERIRT 246 Query 245 LER---GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVAL 301 L R GW D G + D V+LAVPAP+LA L+ GIAPR AAA I ASSAVVAL Sbjct 247 LGRDGDGWS-ADLVG---RVDGVVLAVPAPQLADLLAGIAPRASAAAADIPLASSAVVAL 302 Query 302 AVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQ--RGDVALLRLSFGRFGDEPALTA 359 A+P P SG+LVA D + AKA TLSSRKW +V L+R SFGRFGD + A Sbjct 303 ALPIRVDLPQNSGILVATDATLGAKAFTLSSRKWPHLAEREVTLVRASFGRFGDAAVVDA 362 Query 360 SDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELR---AGLPPTL 416 DD+L+A A DL TV GV+ +PV V V+RW +PQYGPGH D VA + AGL L Sbjct 363 PDDELIAAARRDLATVTGVSAEPVAVHVQRWHGGLPQYGPGHLDRVAVIEQEVAGL-DGL 421 Query 417 AVAGSYLDGIGVPACV 432 V+G+ L G+GVPACV Sbjct 422 EVSGALLHGVGVPACV 437 >gi|226306335|ref|YP_002766295.1| protoporphyrinogen oxidase [Rhodococcus erythropolis PR4] gi|226185452|dbj|BAH33556.1| protoporphyrinogen oxidase [Rhodococcus erythropolis PR4] Length=453 Score = 370 bits (950), Expect = 3e-100, Method: Compositional matrix adjust. Identities = 233/447 (53%), Positives = 295/447 (66%), Gaps = 11/447 (2%) Query 5 SYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVL 64 S V+GGGISGL +AYRLR+++G A IT+ + + RLGG LRT +GG P+D+GAEAF+ Sbjct 7 SVAVIGGGISGLVAAYRLRRSLGSVADITVVDDSPRLGGKLRTIDLGGGPIDIGAEAFIA 66 Query 65 RRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDAT 124 RRPE+PALLAELGL+D+ + G PLI+SQ L+ LP T++GIP+S+ S+ LVD+ T Sbjct 67 RRPEVPALLAELGLTDQIVYPAGLSPLIWSQGSLNRLPAGTLMGIPASSESVRDLVDEQT 126 Query 125 LARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAA 184 L+RI AE PF W GSD +VA+LV+ RFGDQVV+RSVDPLL GVY+G A TIG+RAA Sbjct 127 LSRIAAEPGAPFEWTRGSDCSVAELVSQRFGDQVVSRSVDPLLGGVYSGLAETIGVRAAL 186 Query 185 PSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQ 244 P++AAALD GA S+TDAV A+P + GPVFGAL GY +LLD L + + +VR Sbjct 187 PTLAAALDAGAQSLTDAVAAAVPTPTPGPVFGALRDGYGILLDALRQAADATFVRGEASG 246 Query 245 LER---GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVAL 301 L R GW + D G DAVILAVPAPR A L+ G+ A I ASSAVVAL Sbjct 247 LRRDGKGWNV-DPLG---SVDAVILAVPAPRAAVLLAGVDADIARIASGIELASSAVVAL 302 Query 302 AVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVA--LLRLSFGRFGDEPALTA 359 +PG P SG+LVA D AKA TLSSRKW D L+R+SFGRFG + Sbjct 303 RLPGQVDLPQNSGILVATDADLTAKAFTLSSRKWTHLADRGEHLVRVSFGRFGASEIVDR 362 Query 360 SDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPT--LA 417 D +L+ A DL TV G+ +P V+RW +PQY PGH ++VAE+ +G+ L Sbjct 363 PDGELIELARADLETVTGITEEPGASFVQRWHGGLPQYSPGHTEIVAEIESGMTQFDGLE 422 Query 418 VAGSYLDGIGVPACVGAAGRAVTSVIE 444 VAGS+L G+GVPACV A T + E Sbjct 423 VAGSWLHGVGVPACVAVGTTAATRIFE 449 >gi|308380437|ref|ZP_07669194.1| hypothetical protein TMKG_03107 [Mycobacterium tuberculosis SUMu011] gi|308361478|gb|EFP50329.1| hypothetical protein TMKG_03107 [Mycobacterium tuberculosis SUMu011] Length=189 Score = 368 bits (944), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 189/189 (100%), Positives = 189/189 (100%), Gaps = 0/189 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL Sbjct 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAA 189 RAAAPSVAA Sbjct 181 RAAAPSVAA 189 >gi|229491251|ref|ZP_04385077.1| protoporphyrinogen oxidase [Rhodococcus erythropolis SK121] gi|229321790|gb|EEN87585.1| protoporphyrinogen oxidase [Rhodococcus erythropolis SK121] Length=453 Score = 359 bits (921), Expect = 6e-97, Method: Compositional matrix adjust. Identities = 232/447 (52%), Positives = 297/447 (67%), Gaps = 11/447 (2%) Query 5 SYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVL 64 S V+GGGISGL +AYRLR+++G +A IT+ + + RLGG LRT +GG P+D+GAEAF+ Sbjct 7 SVAVIGGGISGLVAAYRLRRSLGSEADITIVDDSPRLGGKLRTIDLGGGPIDIGAEAFIA 66 Query 65 RRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDAT 124 RRPE+PALLAELGL+D+ + G PLI+SQ L+ LP T++GIP+SA S+ LVD+ T Sbjct 67 RRPEVPALLAELGLTDQIVYPAGLSPLIWSQGSLNRLPTGTLMGIPASAESVRDLVDEQT 126 Query 125 LARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAA 184 LARI AEA P W GSD +VA+LV+ RFGDQVV+RSVDPLL GVY+G A TIG+RAA Sbjct 127 LARIAAEAGVPLEWTRGSDCSVAELVSQRFGDQVVSRSVDPLLGGVYSGLAETIGVRAAL 186 Query 185 PSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQ 244 P++AAALD G+ S+TDAV ALP + GPVFGAL GY +LLD L + + +VR Sbjct 187 PTLAAALDAGSRSLTDAVAAALPTPAPGPVFGALRDGYGILLDALQQAADATFVRGEASG 246 Query 245 LER---GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVAL 301 L GW + D G DAVILAVPAPR A L+ G+ + +I ASSAVVAL Sbjct 247 LRSDGAGWNV-DPLG---SVDAVILAVPAPRAAALLAGVDADVASTVARIELASSAVVAL 302 Query 302 AVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVA--LLRLSFGRFGDEPALTA 359 + G P SG+LVA D AKA TLSSRKW D L+R+SFGRFG + Sbjct 303 RLSGQVELPQNSGILVATDADLTAKAFTLSSRKWTHLADRGEHLVRVSFGRFGASEIVDR 362 Query 360 SDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPT--LA 417 D +L+ +A DL TV G+ +P V+RW +PQY PGH ++VAE+ +G+ LA Sbjct 363 PDGELIDFARADLETVTGITEEPGATFVQRWHGGLPQYAPGHTEIVAEIESGMTQFDGLA 422 Query 418 VAGSYLDGIGVPACVGAAGRAVTSVIE 444 +AGS+L G+GVPACV A T + E Sbjct 423 LAGSWLHGVGVPACVAVGTTAATRIFE 449 >gi|326904291|gb|EGE51224.1| LOW QUALITY PROTEIN: protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis W-148] Length=453 Score = 353 bits (907), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 181/181 (100%), Positives = 181/181 (100%), Gaps = 0/181 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL Sbjct 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 Query 181 R 181 R Sbjct 181 R 181 >gi|54025707|ref|YP_119949.1| protoporphyrinogen oxidase [Nocardia farcinica IFM 10152] gi|54017215|dbj|BAD58585.1| putative protoporphyrinogen oxidase [Nocardia farcinica IFM 10152] Length=448 Score = 342 bits (877), Expect = 8e-92, Method: Compositional matrix adjust. Identities = 235/431 (55%), Positives = 288/431 (67%), Gaps = 12/431 (2%) Query 7 CVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRR 66 +VGGGISGL +AYRLR +G A + L + A+R+GG+L T I G+P+DLGAEAFV RR Sbjct 4 AIVGGGISGLVAAYRLRTLLGPAADLVLVDRAERVGGILYTADIQGEPVDLGAEAFVGRR 63 Query 67 PEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLA 126 PE+PALL ELGL D+ + G RPL+++ HPLPP+T++GIPS A SM GLVDD TL Sbjct 64 PEVPALLRELGLEDQLVYPAGKRPLLWAGGATHPLPPRTLMGIPSDAESMRGLVDDDTLD 123 Query 127 RIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPS 186 RI +E+ARP W SD V LVADRFG QVV RSVDPLL GVYAGSA +IG+RAA P+ Sbjct 124 RIASESARPLAWYPDSDLDVHSLVADRFGAQVVERSVDPLLGGVYAGSARSIGVRAALPT 183 Query 187 VAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLE 246 +AAALD GA S+T AV ALPP S PVFG + GY+VLLD LV S + +V A Sbjct 184 LAAALDAGAPSLTHAVAAALPPPSDAPVFGGIRDGYRVLLDALVAASGLRFVAATAATRL 243 Query 247 R----GWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALA 302 GWVL D G DAV++A PAP ARL+ +AP AA I +SSAVVAL+ Sbjct 244 ARASGGWVL-DPLG---LVDAVVVAAPAPVAARLLRYVAPGAADAAAGIELSSSAVVALS 299 Query 303 VPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGD--VALLRLSFGRFGDEPALTAS 360 +P TA P SG+LVA E AKA TLSSRKW + AL+R SFG+FGD+ L S Sbjct 300 LPPDTALPDNSGILVATGEPLRAKAFTLSSRKWPHLAERKTALVRASFGKFGDDAPLRWS 359 Query 361 DDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPT--LAV 418 D +L+A A +DL TV GV + PV+ V+RW + QY PGH D VAE+ + LAV Sbjct 360 DAELIAAATEDLATVTGVPITPVEAVVQRWPGGLAQYAPGHTDRVAEIDRAVAELDGLAV 419 Query 419 AGSYLDGIGVP 429 AG+YL G+GVP Sbjct 420 AGAYLRGVGVP 430 >gi|333919449|ref|YP_004493030.1| protoporphyrinogen oxidase [Amycolicicoccus subflavus DQS3-9A1] gi|333481670|gb|AEF40230.1| Protoporphyrinogen oxidase [Amycolicicoccus subflavus DQS3-9A1] Length=455 Score = 340 bits (872), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 217/456 (48%), Positives = 282/456 (62%), Gaps = 19/456 (4%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 M R V+GGGI+GLT+AYRLRQA+G A IT+ E ++ LGG LRT I P+D+GAE Sbjct 1 MPVRHALVLGGGIAGLTAAYRLRQALGPAAAITVCEASESLGGKLRTLTIDDGPVDVGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGS---MA 117 AFV RRPE+ +L ELGL D + + RP+I++ HPLPP +GIP+S S + Sbjct 61 AFVQRRPEVLSLAKELGLGDELVTPSSVRPVIWADGSAHPLPPGAFMGIPASEASIKGLK 120 Query 118 GLVDDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAAT 177 GLV A EA R FTW+ G+D ++A LV +RFG++VV +SVDPL++GVYAG ++T Sbjct 121 GLVSAAAEGYAAGEAKRLFTWETGADWSLAQLVRERFGEEVVRKSVDPLIAGVYAGDSST 180 Query 178 IGLRAAAPSVAAALDRGATSVTDAVRQALPPGSG-GPVFGALDGGYQVLLDGLVRRSRVH 236 +G+RAA P +A ALD GA S+T AVR A P +G GPVF GYQ LL+ L R + Sbjct 181 VGIRAAIPELARALDSGAASLTAAVRGAFKPATGSGPVFATFRNGYQTLLNALERAAGAE 240 Query 237 WVRARVVQLERGWVLRDETGGRWQ------ADAVILAVPAPRLARLVDGIAPRTHAAARQ 290 V+L + G RW+ AD VILA+PA L ++ G AP AAA + Sbjct 241 ------VRLSASARVLSRAGKRWRTDVASDADIVILALPAHALPGVISGHAPAAAAAAAE 294 Query 291 IVSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGR 350 I ASSAVV A + P SGVLVAG E AKA+TL+SRKW +G LLR+S GR Sbjct 295 IRHASSAVVTFAFDDDSVLPEWSGVLVAGGEKLDAKAVTLTSRKWPHQGGRGLLRVSLGR 354 Query 351 FGDEPALTA-SDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELR 409 FGD+P +TA D+ L+ A DL + G+ VDP V+RW + +PQY PGH V + Sbjct 355 FGDDPPVTALPDENLVRVARADLRVLTGIDVDPRLSTVQRWPDGLPQYEPGHQRRVQAIE 414 Query 410 AGL--PPTLAVAGSYLDGIGVPACVGAAGRAVTSVI 443 G+ P + VAG YL G+GVPAC+ +A AVT I Sbjct 415 EGVLQLPGIGVAGGYLHGVGVPACIASADAAVTKAI 450 >gi|312139467|ref|YP_004006803.1| protoporphyrinogen oxidase hemg [Rhodococcus equi 103S] gi|311888806|emb|CBH48118.1| protoporphyrinogen oxidase HemG [Rhodococcus equi 103S] Length=454 Score = 338 bits (867), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 228/420 (55%), Positives = 276/420 (66%), Gaps = 12/420 (2%) Query 18 SAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAELG 77 +AYRLRQ +G DA IT+ E RLGG LRTE +G P+D+GAEAF+ RRPE+ L+ ELG Sbjct 20 AAYRLRQQLGPDAEITVLEAGSRLGGKLRTESLGDGPVDVGAEAFIARRPEVTELIVELG 79 Query 78 LSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFT 137 + D+ + G +PLI+S+ LHPLP +T++GIPS+A S+AGLVD T+ARI AE PF Sbjct 80 IEDQLVHPAGRQPLIWSEGALHPLPTRTLMGIPSTAQSVAGLVDADTVARIAAEPTMPFD 139 Query 138 WQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATS 197 W +D VA LVA RFG+QVV RSVDPLL GVY+G A +IG+RAA P++AAALD GATS Sbjct 140 WDRSADVDVASLVASRFGEQVVRRSVDPLLGGVYSGLADSIGVRAALPALAAALDAGATS 199 Query 198 VTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWV-RARVVQLER---GWVLRD 253 +T AV ALP S GPVFG L GY LLD L +R H V A V L R GW L D Sbjct 200 LTAAVAAALPTPSPGPVFGTLRDGYGTLLDALRDAARPHTVLDASVTGLRRDGDGWWL-D 258 Query 254 ETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCS 313 G D V+LA+PAP + RLV AP AAR I ASSAVVALA+P T P S Sbjct 259 PVG---HVDGVVLALPAPDMVRLVGASAPALAEAARGIELASSAVVALALPDDTGVPENS 315 Query 314 GVLVAGDESPHAKAITLSSRKWGQ--RGDVALLRLSFGRFGDEPALTASDDQLLAWAADD 371 G+LVA ES AKA TLSSRKW +V L+R S+GRFGD + +SD+QL+ A D Sbjct 316 GILVATGESLGAKAFTLSSRKWPHLAEREVTLVRASYGRFGDAAVVDSSDEQLVTMARAD 375 Query 372 LVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVA--ELRAGLPPTLAVAGSYLDGIGVP 429 L TV GV+ +PVD V RW +PQ PGH D VA E A + VAG+YL G+GVP Sbjct 376 LETVTGVSTEPVDAVVARWHSGLPQLAPGHLDRVAAIETAAADIDGVEVAGAYLYGVGVP 435 >gi|325672645|ref|ZP_08152341.1| protoporphyrinogen oxidase [Rhodococcus equi ATCC 33707] gi|325556522|gb|EGD26188.1| protoporphyrinogen oxidase [Rhodococcus equi ATCC 33707] Length=454 Score = 337 bits (864), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 227/420 (55%), Positives = 275/420 (66%), Gaps = 12/420 (2%) Query 18 SAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRRPEMPALLAELG 77 +AYRLRQ +G DA IT+ E RLGG LRTE +G P+D+GAEAF+ RRPE+ L+ ELG Sbjct 20 AAYRLRQQLGPDAEITVLEAGSRLGGKLRTESLGDGPVDVGAEAFIARRPEVTELIVELG 79 Query 78 LSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLARIDAEAARPFT 137 + D+ + G +PLI+S+ LHPLP +T++GIPS+A S+AGLVD T+ARI AE PF Sbjct 80 IEDQLVHPAGRQPLIWSEGALHPLPTRTLMGIPSTAQSVAGLVDADTVARIAAEPTMPFD 139 Query 138 WQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPSVAAALDRGATS 197 W +D VA LV RFG+QVV RSVDPLL GVY+G A +IG+RAA P++AAALD GATS Sbjct 140 WDRSADVDVASLVGSRFGEQVVRRSVDPLLGGVYSGLADSIGVRAALPALAAALDAGATS 199 Query 198 VTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRRSRVHWV-RARVVQLER---GWVLRD 253 +T AV ALP S GPVFG L GY LLD L +R H V A V L R GW L D Sbjct 200 LTAAVAAALPTPSPGPVFGTLRDGYGTLLDALRDAARPHTVLDASVTGLRRDGDGWWL-D 258 Query 254 ETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCS 313 G D V+LA+PAP + RLV AP AAR I ASSAVVALA+P T P S Sbjct 259 PVG---HVDGVVLALPAPDMVRLVGASAPALAEAARGIELASSAVVALALPDDTGVPENS 315 Query 314 GVLVAGDESPHAKAITLSSRKWGQ--RGDVALLRLSFGRFGDEPALTASDDQLLAWAADD 371 G+LVA ES AKA TLSSRKW +V L+R S+GRFGD + +SD+QL+ A D Sbjct 316 GILVATGESLGAKAFTLSSRKWPHLAEREVTLVRASYGRFGDAAVVDSSDEQLVTMARAD 375 Query 372 LVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVA--ELRAGLPPTLAVAGSYLDGIGVP 429 L TV GV+ +PVD V RW +PQ PGH D VA E A + VAG+YL G+GVP Sbjct 376 LETVTGVSTEPVDAVVARWHSGLPQLAPGHLDRVAAIETAAADIDGVEVAGAYLYGVGVP 435 >gi|343924650|ref|ZP_08764194.1| protoporphyrinogen oxidase [Gordonia alkanivorans NBRC 16433] gi|343765450|dbj|GAA11120.1| protoporphyrinogen oxidase [Gordonia alkanivorans NBRC 16433] Length=469 Score = 333 bits (854), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 220/468 (48%), Positives = 285/468 (61%), Gaps = 29/468 (6%) Query 4 RSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFV 63 R VVGGG+SGLT+AYRLR+ +G DA I + E ++RLGG+L T +GGQ +D+GAEAF+ Sbjct 5 RRIAVVGGGVSGLTAAYRLRRELGADAQIDVLEASERLGGILHTTTVGGQSVDVGAEAFI 64 Query 64 LRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDA 123 +RRPE L+ ELGL DR ++ TG RP ++S RLHPLP ++GIP++ ++A L D A Sbjct 65 VRRPEALGLVHELGLGDRVVSPTGRRPSVWSGGRLHPLPAPALMGIPATPEAVADLADPA 124 Query 124 TLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAA 183 L + E R + W +DP V DLVADRFG VVARSVDP+L GVY+ AA IGLR A Sbjct 125 DLELLRTEPHRLWRWDASADPTVGDLVADRFGPSVVARSVDPMLGGVYSSLAADIGLREA 184 Query 184 APSVAAALDRGATSVTDAVRQALPPGSG-GPVFGALDGGYQVLLDGL-----VRRSRVHW 237 P++ A LD GA ++T AV + +G GPVFG L GGY+VLLD L V + Sbjct 185 LPALVARLDGGAPNLTAAVSGLVADATGSGPVFGTLVGGYRVLLDALRSAAAVEPELCSY 244 Query 238 VRARVVQLERGWVLRDETGGRWQA---DAVILAVPAPRLARLVDGIAPRTHAAARQIVSA 294 VR + GW L G R D VILA+PA + L+ G P A R + A Sbjct 245 VRG-LEPTATGWTLDVAGGAREDIRDYDGVILAIPAWQAGHLLRGSLPDFAAPLRAVRGA 303 Query 295 SSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQ--RGDVAL-LRLSFGRF 351 SS VV++A+ GT P SGVLV ES AKA TLSS+KWG D + +R SFGRF Sbjct 304 SSVVVSIALAPGTPVPDHSGVLVGTGESLRAKAFTLSSQKWGHLSHDDAPVSVRASFGRF 363 Query 352 G-------DEPALTASDDQLLAWAADDLVTVF---GVA---VDPVDVRVRRWIEAMPQYG 398 G +EP + DD+L A +DL V GVA + VD V+RW +P YG Sbjct 364 GAPVPSVDEEPGV---DDRLRTEALEDLDEVCRAAGVAPASPNVVDTYVQRWTNGLPVYG 420 Query 399 PGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEAL 446 PGH +A++ A P LA+AGS G+GVPAC+G AGRAV++++ L Sbjct 421 PGHLATMAQVAASRPRRLALAGSSYAGVGVPACIGQAGRAVSALLTDL 468 >gi|289762848|ref|ZP_06522226.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis GM 1503] gi|289710354|gb|EFD74370.1| protoporphyrinogen oxidase hemY [Mycobacterium tuberculosis GM 1503] Length=291 Score = 333 bits (854), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 168/169 (99%), Positives = 169/169 (100%), Gaps = 0/169 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE Sbjct 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV Sbjct 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSG 169 DDATLARIDAEAARPFTWQVGSDPA+ADLVADRFGDQVVARSVDPLLSG Sbjct 121 DDATLARIDAEAARPFTWQVGSDPALADLVADRFGDQVVARSVDPLLSG 169 >gi|262202197|ref|YP_003273405.1| protoporphyrinogen oxidase [Gordonia bronchialis DSM 43247] gi|262085544|gb|ACY21512.1| protoporphyrinogen oxidase [Gordonia bronchialis DSM 43247] Length=475 Score = 326 bits (835), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 222/448 (50%), Positives = 276/448 (62%), Gaps = 25/448 (5%) Query 7 CVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVLRR 66 VVGGGISGLT+A+RLRQA+G DA I + E +DRLGGVLRT +GG+ +D+GAEAF++RR Sbjct 13 AVVGGGISGLTAAFRLRQALGSDAQIDVVESSDRLGGVLRTVDVGGRAVDVGAEAFIVRR 72 Query 67 PEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDATLA 126 PE AL+ ELGL+D ++ +GARP I+S LHPLP ++GIP+S +AGLVD L Sbjct 73 PEALALIDELGLADDVVSPSGARPAIWSGAGLHPLPAPALMGIPASPEPVAGLVDSDDLD 132 Query 127 RIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAAAPS 186 R+ EA RP W V +P V DLVADRFG VVARSVDP+L GVY+ AA IGLR A P+ Sbjct 133 RLAGEADRPLNWSVTQNPTVGDLVADRFGPSVVARSVDPMLGGVYSSLAADIGLREAIPA 192 Query 187 VAAALDRGATSVTDAVRQALPPGSG--GPVFGALDGGYQVLLDGLVRRSRVHWVRAR-VV 243 +AA LD G+ S+T AVR + G+G GPVFG L GGY+ LLD L + V AR VV Sbjct 193 LAARLDGGSPSLTAAVRSVIDSGAGASGPVFGTLIGGYRRLLDALTAAAAVTPALARAVV 252 Query 244 QL---ERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVA 300 L GW L GG D V+LAVPAP L+ AP A + ASS VV+ Sbjct 253 TLGSGADGWTLGFGDGGSADYDGVVLAVPAPVAGELLTESAPAIGEALVAVPRASSVVVS 312 Query 301 LAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRG---DVALLRLSFGRFG----- 352 +A+ GT P SGVLVA E+ AKA T SSRKW + +R SFGR G Sbjct 313 IALEPGTRLPDHSGVLVATGETLRAKAFTFSSRKWPHLAGDDEPVSVRASFGRHGAPVPD 372 Query 353 --DEPALTASDDQLLAWAADDL------VTVFGVAVDPVDVRVRRWIEAMPQYGPGHADV 404 DEP + ++L+A A DL V V+ VD V+RW +P YGPGH Sbjct 373 EDDEPGVG---ERLVADALADLDAVCAAAGVNAVSARVVDSYVQRWPGGLPVYGPGHLAA 429 Query 405 VAELRAGLPPTLAVAGSYLDGIGVPACV 432 +A + A PP LA+AGS G+GVPAC+ Sbjct 430 MARVDAHRPPRLALAGSAYAGVGVPACI 457 >gi|296171935|ref|ZP_06852980.1| protoporphyrinogen oxidase [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295893868|gb|EFG73640.1| protoporphyrinogen oxidase [Mycobacterium parascrofulaceum ATCC BAA-614] Length=245 Score = 319 bits (817), Expect = 7e-85, Method: Compositional matrix adjust. Identities = 183/249 (74%), Positives = 196/249 (79%), Gaps = 7/249 (2%) Query 207 PPGSGGPVFGALDGGYQVLLDGLVRRSRVHWVRARVVQLER---GWVLRDETGGRWQADA 263 PP +G PVFGALDGGYQVLLD LV R R WV+A V +LE GW L D+TG RW ADA Sbjct 1 PPATGAPVFGALDGGYQVLLDALVERGRPRWVQAGVQRLEPAGPGWALLDDTGARWHADA 60 Query 264 VILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVALAVPGGTAFPHCSGVLVAGDESP 323 VILAVPAPR ARL+ IAP + AAA +I SASS VVALAVPG T FP CSGVLVA E Sbjct 61 VILAVPAPRAARLLADIAPASAAAADRITSASSVVVALAVPGDTPFPECSGVLVATGERL 120 Query 324 HAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASDDQLLAWAADDLVTVFGVAVDPV 383 HAKAITLSSRKWG RG LLR SFGR GD A TASDD+LLAWA DDL TVFG+ VDPV Sbjct 121 HAKAITLSSRKWGARGGAQLLRASFGRCGDGLAETASDDELLAWAVDDLATVFGLRVDPV 180 Query 384 DVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVI 443 D RV+RWI AM QYGPGHAD+VAE+RAGLPP LAVAGSYLDGIGVPACVGAAGRAV Sbjct 181 DARVQRWIGAMSQYGPGHADLVAEMRAGLPPALAVAGSYLDGIGVPACVGAAGRAV---- 236 Query 444 EALDAQVAR 452 EALD +VAR Sbjct 237 EALDTEVAR 245 >gi|296139602|ref|YP_003646845.1| protoporphyrinogen oxidase [Tsukamurella paurometabola DSM 20162] gi|296027736|gb|ADG78506.1| protoporphyrinogen oxidase [Tsukamurella paurometabola DSM 20162] Length=421 Score = 317 bits (811), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 208/445 (47%), Positives = 267/445 (60%), Gaps = 30/445 (6%) Query 5 SYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFVL 64 + VVG GISGL +A RL QA A +T+FE +R+GG LR+E IGG +D+GAEAFV Sbjct 3 NIAVVGAGISGLVAALRLEQA---GARVTVFESGNRVGGKLRSETIGGTRLDVGAEAFVQ 59 Query 65 RRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDAT 124 RRPE+ L AELGL+D +A G RP ++S L +T++G+P Sbjct 60 RRPEVLDLAAELGLADEVVAPAGRRPALFSDGALRGHFGRTLMGVP-------------- 105 Query 125 LARIDAEAAR-PFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAA 183 +DA+ R P +W+ G D ++ DLV RFGD+VV RSVDP++SGV+A A + +RAA Sbjct 106 ---VDADEVRLPMSWKRGGDSSIGDLVRSRFGDEVVERSVDPMVSGVFAAHADDVSVRAA 162 Query 184 APSVAAALDRGATSVTDAVRQALPPGSGGPVFGALDGGYQVLLDGLVRR--SRVHWVRAR 241 P++A LD+G S++ AVR AL + PVFG GGYQ LLD L R R+ + A Sbjct 163 LPALADRLDQGTDSLSTAVRDALGEPTDTPVFGTFRGGYQQLLDALAERLGDRI-MLGAP 221 Query 242 VVQLERGWVLRDETGGRWQADAVILAVPAPRLARLVDGIAPRTHAAARQIVSASSAVVAL 301 V ++ W LR DAV+LAVPAP++ RLV G P AA +I +ASSA+V L Sbjct 222 VPEVRPQWSLRGS-----MFDAVVLAVPAPQVGRLVSGYYPELAAAVGKIPAASSALVTL 276 Query 302 AVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRFGDEPALTASD 361 +P T P SGVLVA E AKAITLS RKW D A +RLSFGR G + D Sbjct 277 RLPDDTPLPDLSGVLVASREQVSAKAITLSGRKWDHLPDGA-VRLSFGRLGVSRIVDDLD 335 Query 362 DQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAGLPPTLAVAGS 421 L+A A +DL TV GV DP V V+RW E +P Y PGH D +A + A P L +AG+ Sbjct 336 AGLIAAAREDLATVLGVTADPTAVHVQRWYEGIPVYLPGHRDTLAAIDAATPAGLVLAGA 395 Query 422 YLDGIGVPACVGAAGRAVTSVIEAL 446 Y DG+GVPAC+ A A SVIE L Sbjct 396 YFDGVGVPACIARAEAAAASVIEQL 420 >gi|167970101|ref|ZP_02552378.1| protoporphyrinogen oxidase [Mycobacterium tuberculosis H37Ra] Length=161 Score = 312 bits (799), Expect = 8e-83, Method: Compositional matrix adjust. Identities = 160/161 (99%), Positives = 161/161 (100%), Gaps = 0/161 (0%) Query 292 VSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRF 351 +SASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRF Sbjct 1 MSASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQRGDVALLRLSFGRF 60 Query 352 GDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAG 411 GDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAG Sbjct 61 GDEPALTASDDQLLAWAADDLVTVFGVAVDPVDVRVRRWIEAMPQYGPGHADVVAELRAG 120 Query 412 LPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 452 LPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR Sbjct 121 LPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEALDAQVAR 161 >gi|326384416|ref|ZP_08206096.1| protoporphyrinogen oxidase [Gordonia neofelifaecis NRRL B-59395] gi|326196761|gb|EGD53955.1| protoporphyrinogen oxidase [Gordonia neofelifaecis NRRL B-59395] Length=462 Score = 306 bits (785), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 213/459 (47%), Positives = 274/459 (60%), Gaps = 19/459 (4%) Query 4 RSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAEAFV 63 R V+G G+SGLT+AYRLR+ GDD TI +++ ADR GG+LR +GG D+GAEAF+ Sbjct 5 RRVAVIGAGVSGLTAAYRLRREFGDDITIDVYDEADRPGGLLRMADVGGTAADVGAEAFI 64 Query 64 LRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLVDDA 123 +RRPE L+ ELGL+DR ++ RP I+S LHPLP ++GIP++ S+AGLVD A Sbjct 65 VRRPEALQLVTELGLADRIVSPGPLRPAIWSGAALHPLPTPALMGIPAAPASVAGLVDAA 124 Query 124 TLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGLRAA 183 L R+ E PF W G DP+V +LV +RFG VVARSVDP+L GVY+ A +GLR A Sbjct 125 DLERMAGEPDAPFAWTPGDDPSVGELVGERFGRSVVARSVDPMLGGVYSALADQLGLREA 184 Query 184 APSVAAALDRGATSVTDAVRQALPPGSG--GPVFGALDGGYQVLLDGLVRRSRVHWVR-- 239 P++A ALD GA S+T AV L G+ GPVFGAL GGY+ L++ L+ R VR Sbjct 185 VPALARALDDGAPSLTAAVDAVLAAGASGTGPVFGALRGGYRELVEALLAAGRAE-VRYG 243 Query 240 ARVVQLERG-----WVLRDETGGR-WQADAVILAVPAPRLARLVDGIAPRTHAAARQIVS 293 VV + G L D GR DA ++AVP ARL+ AP + + + Sbjct 244 TEVVGVRPGAAGVTVTLDDAAEGRAVDYDAAVIAVPIWSAARLLADAAPDVASVFGDVRA 303 Query 294 ASSAVVALAVPGGTAFPHCSGVLVAGDESPHAKAITLSSRKWGQ--RGDVALLRLSFGRF 351 A SAVVA+AV T P SGVLVA D KA+TLSS+KW G V LR SFGR Sbjct 304 AGSAVVAVAVAEETPLPEHSGVLVATDAGLRIKAVTLSSQKWPHLRSGPVRTLRTSFGRL 363 Query 352 GDEPALTASDDQLLAWAADDLVTVFGVAVDP----VDVRVRRWIEAMPQYGPGHADVVAE 407 GD + ++DD+L+ + DL T+F A P VD V+RW +P Y PGH V E Sbjct 364 GDP--VVSTDDELITASVSDLGTLFTAAGLPAPEIVDAVVQRWPGGLPHYAPGHLARVRE 421 Query 408 LRAGLPPTLAVAGSYLDGIGVPACVGAAGRAVTSVIEAL 446 A +P + VAGS G+GVPAC+G A AV + L Sbjct 422 AFAAVPGRIGVAGSGYAGVGVPACIGTAEAAVAGITAYL 460 >gi|254821719|ref|ZP_05226720.1| protoporphyrinogen oxidase [Mycobacterium intracellulare ATCC 13950] Length=195 Score = 293 bits (749), Expect = 6e-77, Method: Compositional matrix adjust. Identities = 159/195 (82%), Positives = 173/195 (89%), Gaps = 0/195 (0%) Query 1 MTPRSYCVVGGGISGLTSAYRLRQAVGDDATITLFEPADRLGGVLRTEHIGGQPMDLGAE 60 MT RSYCVVGGGISGLT+AYRLR ++GDDA ITLF+P +RLGG+LRTE +GG PMDLGAE Sbjct 1 MTSRSYCVVGGGISGLTAAYRLRMSLGDDAAITLFDPGERLGGILRTELVGGAPMDLGAE 60 Query 61 AFVLRRPEMPALLAELGLSDRQLASTGARPLIYSQQRLHPLPPQTVVGIPSSAGSMAGLV 120 AFVLRRPE+PALL EL L+ QL STGARPLIYS QRL PLP TVVGIPSSA S+AGLV Sbjct 61 AFVLRRPELPALLDELNLTGHQLVSTGARPLIYSGQRLRPLPTGTVVGIPSSAASVAGLV 120 Query 121 DDATLARIDAEAARPFTWQVGSDPAVADLVADRFGDQVVARSVDPLLSGVYAGSAATIGL 180 D+AT+ARIDAE +RP W GSDPAVADLV DRFGDQVVARSVDPLLSGVYAGSAATIGL Sbjct 121 DEATVARIDAEPSRPLEWVAGSDPAVADLVGDRFGDQVVARSVDPLLSGVYAGSAATIGL 180 Query 181 RAAAPSVAAALDRGA 195 RAAAP+VAAALDRGA Sbjct 181 RAAAPTVAAALDRGA 195 Lambda K H 0.320 0.136 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 939989406426 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40