BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2681

Length=438
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609818|ref|NP_217197.1|  hypothetical protein Rv2681 [Mycoba...   856    0.0   
gi|308232210|ref|ZP_07664029.1|  conserved alanine rich protein [...   856    0.0   
gi|31793853|ref|NP_856346.1|  hypothetical protein Mb2700 [Mycoba...   855    0.0   
gi|340627682|ref|YP_004746134.1|  hypothetical protein MCAN_27071...   854    0.0   
gi|297635289|ref|ZP_06953069.1|  3'-5' exonuclease [Mycobacterium...   811    0.0   
gi|289570857|ref|ZP_06451084.1|  conserved alanine rich protein [...   809    0.0   
gi|167970096|ref|ZP_02552373.1|  conserved alanine rich protein [...   786    0.0   
gi|240169721|ref|ZP_04748380.1|  hypothetical protein MkanA1_1043...   650    0.0   
gi|118618645|ref|YP_906977.1|  hypothetical protein MUL_3315 [Myc...   609    2e-172
gi|15827504|ref|NP_301767.1|  hypothetical protein ML1040 [Mycoba...   606    3e-171
gi|296171911|ref|ZP_06852975.1|  ribonuclease D [Mycobacterium pa...   591    8e-167
gi|342858448|ref|ZP_08715103.1|  3'-5' exonuclease [Mycobacterium...   578    6e-163
gi|254821715|ref|ZP_05226716.1|  ribonuclease D [Mycobacterium in...   569    4e-160
gi|118463563|ref|YP_882753.1|  ribonuclease D [Mycobacterium aviu...   561    7e-158
gi|336458819|gb|EGO37776.1|  ribonuclease D [Mycobacterium avium ...   560    2e-157
gi|254776017|ref|ZP_05217533.1|  ribonuclease D [Mycobacterium av...   558    6e-157
gi|145224502|ref|YP_001135180.1|  3'-5' exonuclease [Mycobacteriu...   557    1e-156
gi|315444833|ref|YP_004077712.1|  ribonuclease D [Mycobacterium s...   557    1e-156
gi|41408900|ref|NP_961736.1|  hypothetical protein MAP2802 [Mycob...   557    2e-156
gi|298526151|ref|ZP_07013560.1|  3'-5' exonuclease [Mycobacterium...   544    1e-152
gi|120403469|ref|YP_953298.1|  3'-5' exonuclease [Mycobacterium v...   539    5e-151
gi|289758809|ref|ZP_06518187.1|  LOW QUALITY PROTEIN: predicted p...   536    3e-150
gi|118467912|ref|YP_887109.1|  ribonuclease D [Mycobacterium smeg...   534    1e-149
gi|108799177|ref|YP_639374.1|  3'-5' exonuclease [Mycobacterium s...   522    5e-146
gi|333991066|ref|YP_004523680.1|  hypothetical protein JDM601_242...   508    5e-142
gi|289762852|ref|ZP_06522230.1|  conserved alanine rich protein [...   501    1e-139
gi|169630071|ref|YP_001703720.1|  hypothetical protein MAB_2988 [...   481    1e-133
gi|325672651|ref|ZP_08152347.1|  ribonuclease III [Rhodococcus eq...   440    3e-121
gi|312139461|ref|YP_004006797.1|  rnase d [Rhodococcus equi 103S]...   439    4e-121
gi|111023812|ref|YP_706784.1|  ribonuclease III [Rhodococcus jost...   423    4e-116
gi|229491276|ref|ZP_04385102.1|  ribonuclease D [Rhodococcus eryt...   421    2e-115
gi|226306331|ref|YP_002766291.1|  ribonuclease D [Rhodococcus ery...   420    3e-115
gi|54025710|ref|YP_119952.1|  putative RNase D [Nocardia farcinic...   419    6e-115
gi|226366248|ref|YP_002784031.1|  ribonuclease [Rhodococcus opacu...   418    1e-114
gi|326384419|ref|ZP_08206099.1|  3'-5' exonuclease [Gordonia neof...   386    3e-105
gi|294815677|ref|ZP_06774320.1|  putative ribonuclease D [Strepto...   383    3e-104
gi|257056403|ref|YP_003134235.1|  ribonuclease D [Saccharomonospo...   381    1e-103
gi|343924647|ref|ZP_08764191.1|  ribonuclease D [Gordonia alkaniv...   381    1e-103
gi|238063529|ref|ZP_04608238.1|  3'-5' exonuclease [Micromonospor...   377    3e-102
gi|297156498|gb|ADI06210.1|  ribonuclease D [Streptomyces bingche...   374    1e-101
gi|333023774|ref|ZP_08451838.1|  putative ribonuclease [Streptomy...   374    2e-101
gi|284990407|ref|YP_003408961.1|  3'-5' exonuclease [Geodermatoph...   372    5e-101
gi|302525782|ref|ZP_07278124.1|  ribonuclease D [Streptomyces sp....   372    6e-101
gi|256375684|ref|YP_003099344.1|  3'-5' exonuclease [Actinosynnem...   371    2e-100
gi|300784546|ref|YP_003764837.1|  ribonuclease D [Amycolatopsis m...   370    3e-100
gi|302522528|ref|ZP_07274870.1|  ribonuclease D [Streptomyces sp....   370    3e-100
gi|318061059|ref|ZP_07979780.1|  ribonuclease D [Streptomyces sp....   369    5e-100
gi|291436577|ref|ZP_06575967.1|  ribonuclease D [Streptomyces gha...   365    6e-99 
gi|302866117|ref|YP_003834754.1|  3'-5' exonuclease [Micromonospo...   365    8e-99 
gi|302557678|ref|ZP_07310020.1|  ribonuclease D [Streptomyces gri...   364    1e-98 


>gi|15609818|ref|NP_217197.1| hypothetical protein Rv2681 [Mycobacterium tuberculosis H37Rv]
 gi|15842219|ref|NP_337256.1| ribonuclease D, putative [Mycobacterium tuberculosis CDC1551]
 gi|148662522|ref|YP_001284045.1| putative ribonuclease D [Mycobacterium tuberculosis H37Ra]
 41 more sequence titles
 Length=438

 Score =  856 bits (2212),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/438 (100%), Positives = 438/438 (100%), Gaps = 0/438 (0%)

Query  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60
            MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER
Sbjct  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60

Query  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120
            ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP
Sbjct  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120

Query  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180
            CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL
Sbjct  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180

Query  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240
            NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
Sbjct  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240

Query  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  300
            HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG
Sbjct  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  300

Query  301  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  360
            GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE
Sbjct  301  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  360

Query  361  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL  420
            VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL
Sbjct  361  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL  420

Query  421  TAALTGAPDAGAQGDDGS  438
            TAALTGAPDAGAQGDDGS
Sbjct  421  TAALTGAPDAGAQGDDGS  438


>gi|308232210|ref|ZP_07664029.1| conserved alanine rich protein [Mycobacterium tuberculosis SUMu001]
 gi|308371097|ref|ZP_07667091.1| conserved alanine rich protein [Mycobacterium tuberculosis SUMu003]
 gi|308374662|ref|ZP_07667838.1| conserved alanine rich protein [Mycobacterium tuberculosis SUMu006]
 11 more sequence titles
 Length=468

 Score =  856 bits (2211),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 438/438 (100%), Positives = 438/438 (100%), Gaps = 0/438 (0%)

Query  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60
            MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER
Sbjct  31   MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  90

Query  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120
            ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP
Sbjct  91   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  150

Query  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180
            CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL
Sbjct  151  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  210

Query  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240
            NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
Sbjct  211  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  270

Query  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  300
            HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG
Sbjct  271  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  330

Query  301  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  360
            GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE
Sbjct  331  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  390

Query  361  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL  420
            VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL
Sbjct  391  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL  450

Query  421  TAALTGAPDAGAQGDDGS  438
            TAALTGAPDAGAQGDDGS
Sbjct  451  TAALTGAPDAGAQGDDGS  468


>gi|31793853|ref|NP_856346.1| hypothetical protein Mb2700 [Mycobacterium bovis AF2122/97]
 gi|121638556|ref|YP_978780.1| hypothetical protein BCG_2694 [Mycobacterium bovis BCG str. Pasteur 
1173P2]
 gi|224991048|ref|YP_002645737.1| hypothetical alanine rich protein [Mycobacterium bovis BCG str. 
Tokyo 172]
 gi|31619447|emb|CAD94885.1| CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN [Mycobacterium bovis 
AF2122/97]
 gi|121494204|emb|CAL72682.1| Conserved hypothetical alanine rich protein [Mycobacterium bovis 
BCG str. Pasteur 1173P2]
 gi|224774163|dbj|BAH26969.1| hypothetical alanine rich protein [Mycobacterium bovis BCG str. 
Tokyo 172]
 gi|341602594|emb|CCC65270.1| conserved hypothetical alanine rich protein [Mycobacterium bovis 
BCG str. Moreau RDJ]
Length=438

 Score =  855 bits (2209),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/438 (99%), Positives = 437/438 (99%), Gaps = 0/438 (0%)

Query  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60
            MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER
Sbjct  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60

Query  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120
            ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP
Sbjct  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120

Query  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180
            CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL
Sbjct  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180

Query  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240
            NYAALDVELLIELRA ISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
Sbjct  181  NYAALDVELLIELRAVISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240

Query  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  300
            HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG
Sbjct  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  300

Query  301  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  360
            GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE
Sbjct  301  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  360

Query  361  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL  420
            VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL
Sbjct  361  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL  420

Query  421  TAALTGAPDAGAQGDDGS  438
            TAALTGAPDAGAQGDDGS
Sbjct  421  TAALTGAPDAGAQGDDGS  438


>gi|340627682|ref|YP_004746134.1| hypothetical protein MCAN_27071 [Mycobacterium canettii CIPT 
140010059]
 gi|340005872|emb|CCC45038.1| conserved hypothetical alanine rich protein [Mycobacterium canettii 
CIPT 140010059]
Length=438

 Score =  854 bits (2207),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 437/438 (99%), Positives = 437/438 (99%), Gaps = 0/438 (0%)

Query  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60
            MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER
Sbjct  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60

Query  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120
            ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVL TNEWILHSADQDLP
Sbjct  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLGTNEWILHSADQDLP  120

Query  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180
            CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL
Sbjct  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180

Query  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240
            NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
Sbjct  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240

Query  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  300
            HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG
Sbjct  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  300

Query  301  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  360
            GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE
Sbjct  301  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  360

Query  361  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL  420
            VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL
Sbjct  361  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL  420

Query  421  TAALTGAPDAGAQGDDGS  438
            TAALTGAPDAGAQGDDGS
Sbjct  421  TAALTGAPDAGAQGDDGS  438


>gi|297635289|ref|ZP_06953069.1| 3'-5' exonuclease [Mycobacterium tuberculosis KZN 4207]
Length=416

 Score =  811 bits (2095),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 415/416 (99%), Positives = 416/416 (100%), Gaps = 0/416 (0%)

Query  23   LLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEAGT  82
            +LRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEAGT
Sbjct  1    MLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEAGT  60

Query  83   VLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRLA  142
            VLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRLA
Sbjct  61   VLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRLA  120

Query  143  GFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLA  202
            GFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLA
Sbjct  121  GFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLA  180

Query  203  EQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDRI  262
            EQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDRI
Sbjct  181  EQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDRI  240

Query  263  AQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARESP  322
            AQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARESP
Sbjct  241  AQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARESP  300

Query  323  DPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLC  382
            DPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLC
Sbjct  301  DPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLC  360

Query  383  WEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS  438
            WEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS
Sbjct  361  WEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS  416


>gi|289570857|ref|ZP_06451084.1| conserved alanine rich protein [Mycobacterium tuberculosis T17]
 gi|289544611|gb|EFD48259.1| conserved alanine rich protein [Mycobacterium tuberculosis T17]
Length=443

 Score =  809 bits (2090),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 413/413 (100%), Positives = 413/413 (100%), Gaps = 0/413 (0%)

Query  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60
            MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER
Sbjct  31   MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  90

Query  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120
            ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP
Sbjct  91   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  150

Query  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180
            CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL
Sbjct  151  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  210

Query  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240
            NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
Sbjct  211  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  270

Query  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  300
            HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG
Sbjct  271  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  330

Query  301  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  360
            GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE
Sbjct  331  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  390

Query  361  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQL  413
            VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQL
Sbjct  391  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQL  443


>gi|167970096|ref|ZP_02552373.1| conserved alanine rich protein [Mycobacterium tuberculosis H37Ra]
 gi|254551737|ref|ZP_05142184.1| hypothetical protein Mtube_14982 [Mycobacterium tuberculosis 
'98-R604 INH-RIF-EM']
 gi|294994226|ref|ZP_06799917.1| 3'-5' exonuclease [Mycobacterium tuberculosis 210]
 gi|297732285|ref|ZP_06961403.1| 3'-5' exonuclease [Mycobacterium tuberculosis KZN R506]
 gi|313659618|ref|ZP_07816498.1| 3'-5' exonuclease [Mycobacterium tuberculosis KZN V2475]
 gi|339295543|gb|AEJ47654.1| hypothetical protein CCDC5079_2464 [Mycobacterium tuberculosis 
CCDC5079]
 gi|339299161|gb|AEJ51271.1| hypothetical protein CCDC5180_2434 [Mycobacterium tuberculosis 
CCDC5180]
Length=404

 Score =  786 bits (2030),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 403/404 (99%), Positives = 404/404 (100%), Gaps = 0/404 (0%)

Query  35   VTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDP  94
            +TVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDP
Sbjct  1    MTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDP  60

Query  95   LTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVE  154
            LTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVE
Sbjct  61   LTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVE  120

Query  155  RLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLAEQGKTDWAAQEF  214
            RLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLAEQGKTDWAAQEF
Sbjct  121  RLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLAEQGKTDWAAQEF  180

Query  215  EHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRIL  274
            EHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRIL
Sbjct  181  EHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRIL  240

Query  275  PDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARESPDPPEIAEPANGP  334
            PDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARESPDPPEIAEPANGP
Sbjct  241  PDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARESPDPPEIAEPANGP  300

Query  335  PPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPD  394
            PPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPD
Sbjct  301  PPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPD  360

Query  395  PIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS  438
            PIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS
Sbjct  361  PIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS  404


>gi|240169721|ref|ZP_04748380.1| hypothetical protein MkanA1_10437 [Mycobacterium kansasii ATCC 
12478]
Length=433

 Score =  650 bits (1677),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 340/435 (79%), Positives = 367/435 (85%), Gaps = 4/435 (0%)

Query  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60
            MCP+PS A    S  T S PTPLLRPA G+PDL VTVG+I AAAELLDRGRGPFAVDAER
Sbjct  1    MCPDPSPAETEPSGTTASGPTPLLRPASGMPDLSVTVGQIEAAAELLDRGRGPFAVDAER  60

Query  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120
            ASGFRYS RAYLIQIRRA AGTVLIDPVSHGG+P T L PVAEVL  +EWILHSADQDLP
Sbjct  61   ASGFRYSNRAYLIQIRRAGAGTVLIDPVSHGGEPATALQPVAEVLRQDEWILHSADQDLP  120

Query  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180
            CLAEVGMRP ALYDTELAGRLAGFDRVNLA MVERLLGLGL KGHGAADWSKRPLP AWL
Sbjct  121  CLAEVGMRPSALYDTELAGRLAGFDRVNLATMVERLLGLGLAKGHGAADWSKRPLPPAWL  180

Query  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240
            NYAALDVELLIELRAAIS+VL EQGKT WAA+EFEHLR++ESR    +AR DRWRRTSGI
Sbjct  181  NYAALDVELLIELRAAISQVLTEQGKTGWAAEEFEHLRTYESRSSAVSARPDRWRRTSGI  240

Query  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  300
            HKV DRRGLAAVRELW ARDRIAQ RDIAPRRILPDSAIIDAAIADP+SV+DL+ALPVFG
Sbjct  241  HKVRDRRGLAAVRELWLARDRIAQLRDIAPRRILPDSAIIDAAIADPRSVEDLIALPVFG  300

Query  301  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  360
            GR QRR+AA W AAL AARE+ +PPE+ E ANGPP P RW RRKP AAARL+A RAAL E
Sbjct  301  GRKQRRNAATWLAALEAARENQNPPEVTESANGPPLPARWSRRKPEAAARLEAVRAALAE  360

Query  361  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPIL  420
            +SQRV VPTENLVSP+LVRRLCWEW    Q + D   A++ +LR G ARAWQ  LVVP +
Sbjct  361  LSQRVGVPTENLVSPELVRRLCWEWAGPRQGAAD---AIDEFLRAGHARAWQRRLVVPAM  417

Query  421  TAALTGAPDAGAQGD  435
             AA+T A +A   GD
Sbjct  418  AAAITRA-NAQPDGD  431


>gi|118618645|ref|YP_906977.1| hypothetical protein MUL_3315 [Mycobacterium ulcerans Agy99]
 gi|183982048|ref|YP_001850339.1| hypothetical protein MMAR_2035 [Mycobacterium marinum M]
 gi|118570755|gb|ABL05506.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99]
 gi|183175374|gb|ACC40484.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=435

 Score =  609 bits (1571),  Expect = 2e-172, Method: Compositional matrix adjust.
 Identities = 321/418 (77%), Positives = 357/418 (86%), Gaps = 2/418 (0%)

Query  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60
            MC   S  G    EGT  E TPLL PA G+P+L VT G+I AAA LLDRG GPFAVDAER
Sbjct  1    MCSALSPEGNEPPEGTAPEATPLLSPASGVPELSVTAGQIEAAATLLDRGSGPFAVDAER  60

Query  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120
            ASGFRYS RAYLIQIRRA AGTVLIDPVSHGGDPLTVL P+AEVL+ +EWILHSADQDLP
Sbjct  61   ASGFRYSNRAYLIQIRRAGAGTVLIDPVSHGGDPLTVLQPLAEVLAKDEWILHSADQDLP  120

Query  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180
            CLAEVGMRP ALYDTELAGRLAG+DRVNLA MVERLLG+GL KGHGAADWSKRPLPS WL
Sbjct  121  CLAEVGMRPSALYDTELAGRLAGYDRVNLATMVERLLGMGLVKGHGAADWSKRPLPSDWL  180

Query  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240
            NYAALDVELLIELR+AIS VLAEQGK+DWAAQEFE+LR+FESR  PA A+ DRWRRTSGI
Sbjct  181  NYAALDVELLIELRSAISGVLAEQGKSDWAAQEFEYLRTFESRWVPATAKPDRWRRTSGI  240

Query  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFG  300
            HKV DRRGLAAVRELW  RDRIA+RRDIAPRRILPDSAIIDAA++DPKSV+DLV+LPVFG
Sbjct  241  HKVRDRRGLAAVRELWITRDRIAERRDIAPRRILPDSAIIDAALSDPKSVEDLVSLPVFG  300

Query  301  GRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTE  360
            GRNQRR+A +W  AL  AR+S  PPE+AEP+NGPP P RW RRKP AAARL+AARAAL+E
Sbjct  301  GRNQRRNATMWLGALDVARKSQHPPEVAEPSNGPPVPARWSRRKPEAAARLEAARAALSE  360

Query  361  VSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVP  418
            VS  V VPTENLV+P+LVRRLCW+W  ++ +  +  + ++ +L TGQAR WQ ELVVP
Sbjct  361  VSDSVGVPTENLVTPELVRRLCWDWAPVAAA--EITSTIDEFLATGQARVWQRELVVP  416


>gi|15827504|ref|NP_301767.1| hypothetical protein ML1040 [Mycobacterium leprae TN]
 gi|221229981|ref|YP_002503397.1| hypothetical protein MLBr_01040 [Mycobacterium leprae Br4923]
 gi|699161|gb|AAA62926.1| u1764u [Mycobacterium leprae]
 gi|13093054|emb|CAC31421.1| conserved hypothetical protein [Mycobacterium leprae]
 gi|219933088|emb|CAR71135.1| conserved hypothetical protein [Mycobacterium leprae Br4923]
Length=429

 Score =  606 bits (1562),  Expect = 3e-171, Method: Compositional matrix adjust.
 Identities = 322/420 (77%), Positives = 354/420 (85%), Gaps = 10/420 (2%)

Query  15   GTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQ  74
            GTE +PTPL  PAGGIP+L VT  EIAAAAE LD+G GPFAVD ERASGFRYS RAYLIQ
Sbjct  11   GTEPDPTPLHYPAGGIPNLSVTPSEIAAAAERLDQGYGPFAVDTERASGFRYSNRAYLIQ  70

Query  75   IRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYD  134
            IRRA AGTVLIDPVSHG DPLT L PVAEV+S +EWILHSADQDLPCLAEVGMRPPALYD
Sbjct  71   IRRANAGTVLIDPVSHGNDPLTALRPVAEVISKDEWILHSADQDLPCLAEVGMRPPALYD  130

Query  135  TELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELR  194
            TELAGRLAGFDRVNLA MV+RLLG  L KGHGAADWSKRPLPS WLNYAALDVELLIELR
Sbjct  131  TELAGRLAGFDRVNLATMVQRLLGFELAKGHGAADWSKRPLPSDWLNYAALDVELLIELR  190

Query  195  AAISRVLAEQGKTDWAAQEFEHLRSFESR-------PPPAAARQDRWRRTSGIHKVHDRR  247
             AIS+VLAEQ KTDWA QEF +LR++ +R       PP    R+DRWRRTSGI +V DRR
Sbjct  191  TAISKVLAEQDKTDWATQEFNYLRTYATRGATTETIPP---TRRDRWRRTSGIRRVRDRR  247

Query  248  GLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRS  307
             LAAVRELW  RD IAQRRDIAPRRILPD+AIIDAAIADPK++D+L+A+PVFGG NQRRS
Sbjct  248  ALAAVRELWATRDHIAQRRDIAPRRILPDTAIIDAAIADPKTIDELIAMPVFGGANQRRS  307

Query  308  AAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRV  367
            AA+W AAL  AR+S D P+ AEP+N PPPPGRW RRKP AAARL+AARAAL  VSQRV V
Sbjct  308  AAMWLAALETARQSQDLPDEAEPSNVPPPPGRWARRKPDAAARLEAARAALATVSQRVGV  367

Query  368  PTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGA  427
            PTENLVSP+LVRRLCW+WE + +SS DP+ AVE YLR GQARAWQ ELVV IL +A+  +
Sbjct  368  PTENLVSPELVRRLCWDWEVLPESSVDPVNAVEEYLRVGQARAWQRELVVTILASAVKSS  427


>gi|296171911|ref|ZP_06852975.1| ribonuclease D [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295893910|gb|EFG73681.1| ribonuclease D [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=430

 Score =  591 bits (1524),  Expect = 8e-167, Method: Compositional matrix adjust.
 Identities = 330/432 (77%), Positives = 358/432 (83%), Gaps = 5/432 (1%)

Query  3    PEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERAS  62
            PE    G    +  E +PTPLLRPA GIPDL VTVGEI AAAELL RGRGPFAVDAERAS
Sbjct  4    PEAHGPGGTAPDSAEPQPTPLLRPAEGIPDLSVTVGEIEAAAELLGRGRGPFAVDAERAS  63

Query  63   GFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCL  122
            GFRYS RAYLIQIRRA AGTVLIDPVSHG DPL  L PVAEVL  +EWILHSADQDLPCL
Sbjct  64   GFRYSNRAYLIQIRRAGAGTVLIDPVSHGADPLEALRPVAEVLDEDEWILHSADQDLPCL  123

Query  123  AEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNY  182
            AEVG++PPALYDTELAGRLAGF+RVNLA MVERLLG GL KGHGAADWSKRPLP  WLNY
Sbjct  124  AEVGLQPPALYDTELAGRLAGFERVNLATMVERLLGSGLAKGHGAADWSKRPLPEEWLNY  183

Query  183  AALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHK  242
            AALDVELLIELR AI+ VLA+QGKT WAA+EF++LR   SR P AAAR DRWRRTSGIH+
Sbjct  184  AALDVELLIELRGAIADVLAQQGKTGWAAEEFDYLRQVGSRDPSAAARPDRWRRTSGIHR  243

Query  243  VHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGR  302
            V D+RGLAAVRELW  RDRIAQRRDIAPRRILPDSAII+AA+ DPK+++DL ALPVFGGR
Sbjct  244  VRDQRGLAAVRELWLTRDRIAQRRDIAPRRILPDSAIIEAALTDPKTIEDLTALPVFGGR  303

Query  303  NQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVS  362
            NQRRSAA W  AL AAR++ +PP  AEP NGPPPP RW RRKP AAARL+AARAAL+EVS
Sbjct  304  NQRRSAATWLGALEAARQTKNPPADAEPPNGPPPPARWSRRKPEAAARLEAARAALSEVS  363

Query  363  QRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTA  422
            +RV VPTENLVSPDLVRRLCW+WE     +PDP  AVE +LR GQAR WQ ELV P+L  
Sbjct  364  ERVNVPTENLVSPDLVRRLCWDWE----GAPDPFEAVETFLRAGQARPWQRELVDPVLAR  419

Query  423  ALTGAPDAGAQG  434
            AL   PD  A G
Sbjct  420  ALQ-PPDDDAGG  430


>gi|342858448|ref|ZP_08715103.1| 3'-5' exonuclease [Mycobacterium colombiense CECT 3035]
 gi|342134152|gb|EGT87332.1| 3'-5' exonuclease [Mycobacterium colombiense CECT 3035]
Length=431

 Score =  578 bits (1490),  Expect = 6e-163, Method: Compositional matrix adjust.
 Identities = 316/415 (77%), Positives = 353/415 (86%), Gaps = 4/415 (0%)

Query  15   GTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQ  74
            GT+  PTPL RP+ G+P + V+V EI AAA+ LDRG GPFAVDAERASGFRYS RAYLIQ
Sbjct  18   GTDPAPTPLPRPSEGVPAISVSVHEIEAAAQRLDRGHGPFAVDAERASGFRYSNRAYLIQ  77

Query  75   IRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYD  134
            IRRA +GTVLIDPVSHGG+PL  L PVAEVL ++EWILHSADQDLPCLAEVGMRPPALYD
Sbjct  78   IRRAGSGTVLIDPVSHGGEPLEALRPVAEVLGSDEWILHSADQDLPCLAEVGMRPPALYD  137

Query  135  TELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELR  194
            TELAGRLAGFDRVNLA MVERLLG GL KGHGAADWSKRPLP+ WLNYAALDVELLIELR
Sbjct  138  TELAGRLAGFDRVNLATMVERLLGFGLAKGHGAADWSKRPLPAEWLNYAALDVELLIELR  197

Query  195  AAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRE  254
            AAI+ VLAEQGKTDWAAQEF++L    S+ P AA R+DRWRRTSGIH+V D+RGLAAVRE
Sbjct  198  AAIADVLAEQGKTDWAAQEFDYLCDTGSKDPGAAVRRDRWRRTSGIHRVRDQRGLAAVRE  257

Query  255  LWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAA  314
            LW  RDRIAQRRDIAPRRILPDSAIIDAA+A+P ++++LVALPVFGGRNQRRSAA W  A
Sbjct  258  LWLTRDRIAQRRDIAPRRILPDSAIIDAALANPTTIEELVALPVFGGRNQRRSAATWLGA  317

Query  315  LAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVS  374
            L  AR + +PP  +EP NGPPPP RW RRKP AAARL+AAR+AL+EVS+RV VPTENLVS
Sbjct  318  LDEARRNKNPPGDSEPPNGPPPPARWSRRKPEAAARLEAARSALSEVSERVHVPTENLVS  377

Query  375  PDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPD  429
            PDLVRRLCW+W      +PDP+ AVEA+LR GQAR WQ ELV P+L  AL   P+
Sbjct  378  PDLVRRLCWDW----TPAPDPLDAVEAFLRAGQARPWQRELVDPVLARALQAPPE  428


>gi|254821715|ref|ZP_05226716.1| ribonuclease D [Mycobacterium intracellulare ATCC 13950]
Length=430

 Score =  569 bits (1466),  Expect = 4e-160, Method: Compositional matrix adjust.
 Identities = 327/422 (78%), Positives = 360/422 (86%), Gaps = 4/422 (0%)

Query  3    PEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERAS  62
            P P   G++    TE  PTPL RPA G+P + V+V EI AAAE LDRGRGPFAVDAERAS
Sbjct  4    PSPDGPGSSAPGSTEPAPTPLPRPAEGVPPISVSVYEIEAAAERLDRGRGPFAVDAERAS  63

Query  63   GFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCL  122
            GFRYS RAYLIQIRRA +GTVLIDPVSHG DPL  L PVAEVL T+EWILHSADQDLPCL
Sbjct  64   GFRYSNRAYLIQIRRAGSGTVLIDPVSHGRDPLEALRPVAEVLGTDEWILHSADQDLPCL  123

Query  123  AEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNY  182
            AEVGMRPPALYDTELAGRLAGF+RVNLA MVERLLG GL KGHGAADWSKRPLP+ WLNY
Sbjct  124  AEVGMRPPALYDTELAGRLAGFERVNLATMVERLLGFGLAKGHGAADWSKRPLPAEWLNY  183

Query  183  AALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHK  242
            AALDVELLIELRAAI+ VLA QGKTDWAAQEF++LR   S+ P AAAR+DRWRRTSGIH+
Sbjct  184  AALDVELLIELRAAIAEVLAGQGKTDWAAQEFDYLRDTGSKDPGAAARRDRWRRTSGIHR  243

Query  243  VHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGR  302
            V D+RGLAAVRELW  RD+IAQRRDIAPRRILPDSAIIDAA+A+P +V++LVALPVFGGR
Sbjct  244  VRDKRGLAAVRELWLTRDQIAQRRDIAPRRILPDSAIIDAALANPTTVEELVALPVFGGR  303

Query  303  NQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVS  362
            NQRRSAA W AAL AAR++ +PP  AEP NGPPPP RW RRKP AAARL+AARAAL+EVS
Sbjct  304  NQRRSAATWLAALEAARQNKNPPVDAEPPNGPPPPARWSRRKPEAAARLEAARAALSEVS  363

Query  363  QRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTA  422
            +RV VPTENLVSPDLVRRLCW+WE    ++PDP  AVEA+LR GQAR WQ ELV P+L  
Sbjct  364  ERVHVPTENLVSPDLVRRLCWDWE----AAPDPFEAVEAFLRAGQARPWQRELVDPVLAR  419

Query  423  AL  424
            AL
Sbjct  420  AL  421


>gi|118463563|ref|YP_882753.1| ribonuclease D [Mycobacterium avium 104]
 gi|118164850|gb|ABK65747.1| ribonuclease D [Mycobacterium avium 104]
Length=428

 Score =  561 bits (1446),  Expect = 7e-158, Method: Compositional matrix adjust.
 Identities = 317/418 (76%), Positives = 351/418 (84%), Gaps = 5/418 (1%)

Query  20   PTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAE  79
            P PL  P+ G+P +  +V +I  AA  LDRGRGPFAVDAERASGFRYS RAYLIQIRRA 
Sbjct  16   PIPLPHPSEGVPPISASVPDIEDAARRLDRGRGPFAVDAERASGFRYSNRAYLIQIRRAG  75

Query  80   AGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAG  139
            AGTVLIDPVSHG DP+  L PVAEVL ++EWILHSADQDLPCLAEVGMRPPALYDTELAG
Sbjct  76   AGTVLIDPVSHGADPVRALRPVAEVLGSDEWILHSADQDLPCLAEVGMRPPALYDTELAG  135

Query  140  RLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISR  199
            RLAGF+RVNLA MVERLLG GL KGHGAADWSKRPLP+ WLNYAALDVELLIELRAAI+ 
Sbjct  136  RLAGFERVNLATMVERLLGFGLAKGHGAADWSKRPLPAEWLNYAALDVELLIELRAAIAD  195

Query  200  VLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTAR  259
            VLAEQGKTDWAAQEF++LR   S+ P  AAR+DRWRRTSGIH+V D+RGLAAVRELW  R
Sbjct  196  VLAEQGKTDWAAQEFDYLREAGSKEPGPAARRDRWRRTSGIHRVRDQRGLAAVRELWLTR  255

Query  260  DRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAAR  319
            DRIAQRRDIAPRRILPDSAII+AA+A+P ++++LVALPVFGGRNQRRSAA W AAL AAR
Sbjct  256  DRIAQRRDIAPRRILPDSAIIEAALANPTTIEELVALPVFGGRNQRRSAATWLAALDAAR  315

Query  320  ESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVR  379
            +S +PP  +EP NGPPPP RW RRKP AAARL+AARAAL EVS+RV VPTENLV+PDLVR
Sbjct  316  QSENPPVDSEPPNGPPPPARWSRRKPEAAARLEAARAALAEVSERVHVPTENLVAPDLVR  375

Query  380  RLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDG  437
            RLCW+WE     +PDP AAVEA+L  G AR WQ ELV P+L  AL   P A A  DDG
Sbjct  376  RLCWDWE----PTPDPFAAVEAFLCAGHARPWQRELVDPVLARALQQPPPAVAD-DDG  428


>gi|336458819|gb|EGO37776.1| ribonuclease D [Mycobacterium avium subsp. paratuberculosis S397]
Length=428

 Score =  560 bits (1442),  Expect = 2e-157, Method: Compositional matrix adjust.
 Identities = 316/418 (76%), Positives = 351/418 (84%), Gaps = 5/418 (1%)

Query  20   PTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAE  79
            P PL  P+ G+P +  +V +I  AA  LDRGRGPFAVDAERASGFRYS RAYLIQIRRA 
Sbjct  16   PIPLPHPSEGVPPISASVPDIEDAARRLDRGRGPFAVDAERASGFRYSNRAYLIQIRRAG  75

Query  80   AGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAG  139
            AGTVLIDPVSHG DP+  L PVAEVL ++EWILHSADQDLPCLAEVGMRPPALYDTELAG
Sbjct  76   AGTVLIDPVSHGADPVRALRPVAEVLGSDEWILHSADQDLPCLAEVGMRPPALYDTELAG  135

Query  140  RLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISR  199
            RLAGF+RVNLA MVERLLG GL KGHGAADWSKRPLP+ WLNYAALDVELLIELRAAI+ 
Sbjct  136  RLAGFERVNLATMVERLLGFGLAKGHGAADWSKRPLPAEWLNYAALDVELLIELRAAIAD  195

Query  200  VLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTAR  259
            VLAEQGKTDWAAQEF++LR   S+ P  AAR+DRWRRTSGIH+V D+RGLAAVRELW  R
Sbjct  196  VLAEQGKTDWAAQEFDYLREAGSKEPGPAARRDRWRRTSGIHRVRDQRGLAAVRELWLTR  255

Query  260  DRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAAR  319
            DRIAQRRDIAPRRILPDSAII+AA+A+P ++++LVALPVFGGRNQRRSAA W AAL AAR
Sbjct  256  DRIAQRRDIAPRRILPDSAIIEAALANPTTIEELVALPVFGGRNQRRSAATWLAALDAAR  315

Query  320  ESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVR  379
            +S +PP  +EP NGPPPP RW RRKP AAARL+AARAAL EVS+RV VPTENLV+PDLVR
Sbjct  316  QSENPPVDSEPPNGPPPPARWSRRKPEAAARLEAARAALAEVSERVHVPTENLVAPDLVR  375

Query  380  RLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDG  437
            RLCW+WE     +PDP AAV+A+L  G AR WQ ELV P+L  AL   P A A  DDG
Sbjct  376  RLCWDWE----PTPDPFAAVDAFLCAGHARPWQRELVDPVLARALQQPPPAVAD-DDG  428


>gi|254776017|ref|ZP_05217533.1| ribonuclease D [Mycobacterium avium subsp. avium ATCC 25291]
Length=416

 Score =  558 bits (1438),  Expect = 6e-157, Method: Compositional matrix adjust.
 Identities = 316/418 (76%), Positives = 350/418 (84%), Gaps = 5/418 (1%)

Query  20   PTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAE  79
            P PL  P+ G+P +  +V +I  AA  LDRGRGPFAVDAERASGFRYS RAYLIQIRRA 
Sbjct  4    PIPLPHPSEGVPPISASVPDIEDAARRLDRGRGPFAVDAERASGFRYSNRAYLIQIRRAG  63

Query  80   AGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAG  139
            AGTVLIDPVSHG DP+  L PVAEVL ++EWILHSADQDLPCLAEVGMRPPALYDTELAG
Sbjct  64   AGTVLIDPVSHGADPVRALRPVAEVLGSDEWILHSADQDLPCLAEVGMRPPALYDTELAG  123

Query  140  RLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISR  199
            RLAGF+RVNLA MVERLLG GL KGHGAADWSKRPLP+ WLNYAALDVELLIELRAAI+ 
Sbjct  124  RLAGFERVNLATMVERLLGFGLAKGHGAADWSKRPLPAEWLNYAALDVELLIELRAAIAD  183

Query  200  VLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTAR  259
            VLA QGKTDWAAQEF++LR   S+ P  AAR+DRWRRTSGIH+V D+RGLAAVRELW  R
Sbjct  184  VLAGQGKTDWAAQEFDYLREAGSKEPGPAARRDRWRRTSGIHRVRDQRGLAAVRELWLTR  243

Query  260  DRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAAR  319
            DRIAQRRDIAPRRILPDSAII+AA+A+P ++++LVALPVFGGRNQRRSAA W AAL AAR
Sbjct  244  DRIAQRRDIAPRRILPDSAIIEAALANPTTIEELVALPVFGGRNQRRSAATWLAALDAAR  303

Query  320  ESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVR  379
            +S +PP  +EP NGPPPP RW RRKP AAARL+AARAAL EVS+RV VPTENLV+PDLVR
Sbjct  304  QSENPPVDSEPPNGPPPPARWSRRKPEAAARLEAARAALAEVSERVHVPTENLVAPDLVR  363

Query  380  RLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDG  437
            RLCW+WE     +PDP AAVEA+L  G AR WQ ELV P+L  AL   P A A  DDG
Sbjct  364  RLCWDWE----PTPDPFAAVEAFLCAGHARPWQRELVDPVLARALQQPPPAVAD-DDG  416


>gi|145224502|ref|YP_001135180.1| 3'-5' exonuclease [Mycobacterium gilvum PYR-GCK]
 gi|145216988|gb|ABP46392.1| 3'-5' exonuclease [Mycobacterium gilvum PYR-GCK]
Length=424

 Score =  557 bits (1436),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 295/429 (69%), Positives = 335/429 (79%), Gaps = 9/429 (2%)

Query  2    CPEPSHAGAAES--EGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAE  59
             PEP  AG+A    E T+ E  PLL P  G+PD+  +  EIA AA+LL  G GPFAVDAE
Sbjct  1    MPEPETAGSAPETPEPTDIEAEPLLTPRDGVPDVSSSRMEIARAADLLASGTGPFAVDAE  60

Query  60   RASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDL  119
            RASGFRYS RAYL+QIRR  AGTVLIDPVSHGGDP+ VLAPVA VLST+EW+LH+ADQDL
Sbjct  61   RASGFRYSNRAYLVQIRRVGAGTVLIDPVSHGGDPMEVLAPVAAVLSTDEWVLHAADQDL  120

Query  120  PCLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAW  179
            PCLAE+GMRP ALYDTELAGRLA FDRVNLAAMV+RLLGL LTKGHGAADWSKRPLP  W
Sbjct  121  PCLAEIGMRPTALYDTELAGRLANFDRVNLAAMVQRLLGLQLTKGHGAADWSKRPLPDEW  180

Query  180  LNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSG  239
            LNYAALDVE+L +LR AI+ VL EQGK +WA QEFE+LR+FE  P     R+DRWRRTSG
Sbjct  181  LNYAALDVEVLTDLREAIAAVLDEQGKAEWARQEFEYLRTFEGSP----TRRDRWRRTSG  236

Query  240  IHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVF  299
            IHKV D R LAAVRELWT RD+IA+RRDIAP RILPDSAII AA A+P +++ L ALPVF
Sbjct  237  IHKVRDPRALAAVRELWTTRDQIARRRDIAPGRILPDSAIISAATANPDTIEKLTALPVF  296

Query  300  GGRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALT  359
            GG  QRRSA VW  ALA AR + DPP+  EP+NGPPP  RW RRKP AA RL+AARA LT
Sbjct  297  GGSKQRRSAQVWLDALARARTN-DPPDAQEPSNGPPPASRWSRRKPEAAVRLEAARAELT  355

Query  360  EVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPI  419
             ++Q+V VP ENL+SP+ VRRLCW+W+  +    D  AAVEA+LR   AR WQ EL VP 
Sbjct  356  ALAQQVSVPVENLLSPETVRRLCWDWQPPADG--DATAAVEAFLRDSTARQWQRELTVPA  413

Query  420  LTAALTGAP  428
            L  AL+  P
Sbjct  414  LGRALSEPP  422


>gi|315444833|ref|YP_004077712.1| ribonuclease D [Mycobacterium sp. Spyr1]
 gi|315263136|gb|ADT99877.1| ribonuclease D [Mycobacterium sp. Spyr1]
Length=424

 Score =  557 bits (1436),  Expect = 1e-156, Method: Compositional matrix adjust.
 Identities = 293/429 (69%), Positives = 336/429 (79%), Gaps = 9/429 (2%)

Query  2    CPEPSHAGAAES--EGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAE  59
             PEP  AG+A    E T+ E  PLL P  G+PD+  +  EIA AA+LL  G GPFAVDAE
Sbjct  1    MPEPETAGSAPETPEPTDIEAEPLLTPRDGVPDVSSSRMEIARAADLLASGTGPFAVDAE  60

Query  60   RASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDL  119
            RASGFRYS RAYL+QIRR  AGTVLIDPVSHGGDP+ VLAPVA VLST+EW+LH+ADQDL
Sbjct  61   RASGFRYSNRAYLVQIRRVGAGTVLIDPVSHGGDPMEVLAPVAAVLSTDEWVLHAADQDL  120

Query  120  PCLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAW  179
            PCLAE+GMRP ALYDTELAGRLA FDRVNLAAMV+RLLGL LTKGHGAADWSKRPLP  W
Sbjct  121  PCLAEIGMRPTALYDTELAGRLANFDRVNLAAMVQRLLGLQLTKGHGAADWSKRPLPDEW  180

Query  180  LNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSG  239
            LNYAALDVE+L +LR AI+ +L EQGK +WA QEFE+LR+FE  P     R+DRWRRTSG
Sbjct  181  LNYAALDVEVLTDLREAIAAILDEQGKAEWARQEFEYLRTFEGSP----TRRDRWRRTSG  236

Query  240  IHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVF  299
            IHKV D R LAAVRELWT RD+IA+RRDIAP RILPDSAII AA A+P +++ L ALPVF
Sbjct  237  IHKVRDPRALAAVRELWTTRDQIARRRDIAPGRILPDSAIISAATANPDTIEKLTALPVF  296

Query  300  GGRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALT  359
            GG  QRRSA VW  ALA AR + DPP+  EP+NGPPP  RW RRKP AA RL+AARA LT
Sbjct  297  GGSKQRRSAQVWLDALARARTN-DPPDAQEPSNGPPPASRWSRRKPEAAVRLEAARAELT  355

Query  360  EVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPI  419
             ++Q+V VP ENL+SP+ VRRLCW+W+  +    D  AAV+A+LR   AR WQ EL VP 
Sbjct  356  ALAQQVSVPVENLLSPETVRRLCWDWQPPADG--DATAAVDAFLRESTARQWQRELTVPA  413

Query  420  LTAALTGAP  428
            L+ AL+  P
Sbjct  414  LSRALSEPP  422


>gi|41408900|ref|NP_961736.1| hypothetical protein MAP2802 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41397259|gb|AAS05119.1| hypothetical protein MAP_2802 [Mycobacterium avium subsp. paratuberculosis 
K-10]
Length=428

 Score =  557 bits (1435),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 314/418 (76%), Positives = 349/418 (84%), Gaps = 5/418 (1%)

Query  20   PTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAE  79
            P PL  P+ G+P +  +V +I  AA  LDRGRGPFAVDAERASGFRYS RAYLIQIRRA 
Sbjct  16   PIPLPHPSEGVPPISASVPDIEDAARRLDRGRGPFAVDAERASGFRYSNRAYLIQIRRAG  75

Query  80   AGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAG  139
            AGTVLIDPVSHG DP+  L PVAEVL ++EWILHSADQDLPCLAEVGMRPPALYDTELAG
Sbjct  76   AGTVLIDPVSHGADPVRALRPVAEVLGSDEWILHSADQDLPCLAEVGMRPPALYDTELAG  135

Query  140  RLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISR  199
            RLAGF+RVNLA MVERLLG GL KGHGAADWSKRPLP+ WLNYAALDVELLIELRAAI+ 
Sbjct  136  RLAGFERVNLATMVERLLGFGLAKGHGAADWSKRPLPAEWLNYAALDVELLIELRAAIAD  195

Query  200  VLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTAR  259
            VLAEQGKTDWAAQEF++LR   S+ P  AAR+DRWRRTSGIH+V D+RGLAAVRELW  R
Sbjct  196  VLAEQGKTDWAAQEFDYLREAGSKEPGPAARRDRWRRTSGIHRVRDQRGLAAVRELWLTR  255

Query  260  DRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAAR  319
            DRIAQRRDIAPRRILPDSAII+AA+A+P ++++LVALPVFGGRNQRRSAA W AAL AAR
Sbjct  256  DRIAQRRDIAPRRILPDSAIIEAALANPTTIEELVALPVFGGRNQRRSAATWLAALDAAR  315

Query  320  ESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVR  379
            +S +PP  +EP NGPPPP RW RRKP AAARL+AARAAL EVS+RV VPTENLV+PDLVR
Sbjct  316  QSENPPVDSEPPNGPPPPARWSRRKPEAAARLEAARAALAEVSERVHVPTENLVAPDLVR  375

Query  380  RLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQGDDG  437
            RLCW+WE     +PDP AAV+A+L  G AR WQ ELV P+L  AL   P      DDG
Sbjct  376  RLCWDWE----PTPDPFAAVDAFLCAGHARPWQRELVDPVLARALQ-QPLPAVADDDG  428


>gi|298526151|ref|ZP_07013560.1| 3'-5' exonuclease [Mycobacterium tuberculosis 94_M4241A]
 gi|298495945|gb|EFI31239.1| 3'-5' exonuclease [Mycobacterium tuberculosis 94_M4241A]
Length=375

 Score =  544 bits (1401),  Expect = 1e-152, Method: Compositional matrix adjust.
 Identities = 273/274 (99%), Positives = 273/274 (99%), Gaps = 0/274 (0%)

Query  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60
            MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER
Sbjct  1    MCPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAER  60

Query  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120
            ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP
Sbjct  61   ASGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLP  120

Query  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180
            CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL
Sbjct  121  CLAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWL  180

Query  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240
            NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI
Sbjct  181  NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGI  240

Query  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRIL  274
            HKVHDRRGLAAVRELWTARDRIAQRRDIAPRR L
Sbjct  241  HKVHDRRGLAAVRELWTARDRIAQRRDIAPRRDL  274


>gi|120403469|ref|YP_953298.1| 3'-5' exonuclease [Mycobacterium vanbaalenii PYR-1]
 gi|119956287|gb|ABM13292.1| 3'-5' exonuclease [Mycobacterium vanbaalenii PYR-1]
Length=426

 Score =  539 bits (1388),  Expect = 5e-151, Method: Compositional matrix adjust.
 Identities = 279/397 (71%), Positives = 325/397 (82%), Gaps = 6/397 (1%)

Query  22   PLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEAG  81
            PLLRP  G+PD+ V+  EIA AA+LL  G GPFAVDAERASGFRYS RAYL+QIRRA AG
Sbjct  25   PLLRPRDGVPDVSVSRYEIAKAADLLASGHGPFAVDAERASGFRYSNRAYLVQIRRAGAG  84

Query  82   TVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGRL  141
            +VLIDPVSHGGDPL VLAPVAEVLS  EW+LH+ADQDLPCLAE+GMRPP+LYDTELAGRL
Sbjct  85   SVLIDPVSHGGDPLEVLAPVAEVLSDAEWVLHAADQDLPCLAEIGMRPPSLYDTELAGRL  144

Query  142  AGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVL  201
            A ++RVNLAAMV+RLLGL LTKGHGAADWSKRPLP  WLNYAALDVE+L++LR AIS VL
Sbjct  145  ANYERVNLAAMVQRLLGLQLTKGHGAADWSKRPLPQDWLNYAALDVEVLVDLRHAISEVL  204

Query  202  AEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDR  261
             EQGK  WAA+EFE+LR+ E+ P     R+DRWRRTSGIHKV D R LAAVRELWT RD+
Sbjct  205  QEQGKEGWAAEEFEYLRTVEATP----TRRDRWRRTSGIHKVRDPRALAAVRELWTTRDQ  260

Query  262  IAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARES  321
            IA+RRDIAP RILPDSAI++AA A+P +++ L ALP+FGG  QRRSAAVW  ALA AR S
Sbjct  261  IARRRDIAPGRILPDSAIVNAATANPDTIEKLTALPIFGGSKQRRSAAVWLDALARARTS  320

Query  322  PDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRL  381
             +PP++ EP+NGPPP  RW RRKP AA RL+AAR  L  ++ RV VP ENL+SP++VRRL
Sbjct  321  -EPPDVQEPSNGPPPASRWARRKPEAAVRLEAARTELAALADRVSVPVENLLSPEIVRRL  379

Query  382  CWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVP  418
            CW+W+ + +      AAV+A+LR   AR WQ ELVVP
Sbjct  380  CWDWKPV-EGVDATAAAVDAFLRDSAARRWQRELVVP  415


>gi|289758809|ref|ZP_06518187.1| LOW QUALITY PROTEIN: predicted protein [Mycobacterium tuberculosis 
T85]
 gi|289714373|gb|EFD78385.1| LOW QUALITY PROTEIN: predicted protein [Mycobacterium tuberculosis 
T85]
Length=277

 Score =  536 bits (1381),  Expect = 3e-150, Method: Compositional matrix adjust.
 Identities = 276/276 (100%), Positives = 276/276 (100%), Gaps = 0/276 (0%)

Query  163  KGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFES  222
            KGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFES
Sbjct  2    KGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFES  61

Query  223  RPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDA  282
            RPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDA
Sbjct  62   RPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDA  121

Query  283  AIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVR  342
            AIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVR
Sbjct  122  AIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVR  181

Query  343  RKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAY  402
            RKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAY
Sbjct  182  RKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAY  241

Query  403  LRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS  438
            LRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS
Sbjct  242  LRTGQARAWQLELVVPILTAALTGAPDAGAQGDDGS  277


>gi|118467912|ref|YP_887109.1| ribonuclease D [Mycobacterium smegmatis str. MC2 155]
 gi|118169199|gb|ABK70095.1| ribonuclease D [Mycobacterium smegmatis str. MC2 155]
Length=415

 Score =  534 bits (1376),  Expect = 1e-149, Method: Compositional matrix adjust.
 Identities = 276/408 (68%), Positives = 326/408 (80%), Gaps = 8/408 (1%)

Query  17   ESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIR  76
            E+E TPLL PA G+P+LCV+  EIA AA  L  G GPFA+DAERASGFRYS RAYL+QIR
Sbjct  13   EAEATPLLTPAEGVPELCVSADEIAGAARQLAGGSGPFAIDAERASGFRYSNRAYLVQIR  72

Query  77   RAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTE  136
            RA AGT LIDPV+HGG P+  L PVA+ L+ +EW+LH+ADQDLPCLAE+G+RP  LYDTE
Sbjct  73   RAGAGTALIDPVNHGGSPIDTLEPVAQTLADDEWVLHAADQDLPCLAEIGLRPGKLYDTE  132

Query  137  LAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAA  196
            LAGRLAGF+RVNLAAMV+RLLGL L KGHGAADWSKRPLP  WLNYAALDVE+L+ELR A
Sbjct  133  LAGRLAGFERVNLAAMVQRLLGLQLMKGHGAADWSKRPLPDEWLNYAALDVEVLLELRHA  192

Query  197  ISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELW  256
            I+ VL EQGKT+WAAQEFEHLR++ ++P     R+DRWRRTSGIHKV + R LAAVRELW
Sbjct  193  IAAVLEEQGKTEWAAQEFEHLRTYVAQP----TRRDRWRRTSGIHKVRNPRALAAVRELW  248

Query  257  TARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALA  316
            T RD IA+ RDIAP RILPD+AII+AA  DPK+  +L ALPVFGG  QRRSA VW  AL 
Sbjct  249  TTRDNIARSRDIAPGRILPDAAIINAATVDPKTTAELTALPVFGGAKQRRSAQVWLDALN  308

Query  317  AARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPD  376
             AR++PDPP  +E +NGPPP  RW RRKP AAARL+AARA L E+S+RV VP ENL++P+
Sbjct  309  RARQNPDPPSASEASNGPPPAARWARRKPEAAARLEAARAGLAELSERVSVPAENLITPE  368

Query  377  LVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            +VRRLCW+W+ ++    D  + VE +L   Q R WQ EL VP+LT AL
Sbjct  369  VVRRLCWDWQPVA----DVASTVEEFLVDNQVRPWQRELTVPVLTVAL  412


>gi|108799177|ref|YP_639374.1| 3'-5' exonuclease [Mycobacterium sp. MCS]
 gi|119868292|ref|YP_938244.1| 3'-5' exonuclease [Mycobacterium sp. KMS]
 gi|126434785|ref|YP_001070476.1| 3'-5' exonuclease [Mycobacterium sp. JLS]
 gi|108769596|gb|ABG08318.1| 3'-5' exonuclease [Mycobacterium sp. MCS]
 gi|119694381|gb|ABL91454.1| 3'-5' exonuclease [Mycobacterium sp. KMS]
 gi|126234585|gb|ABN97985.1| 3'-5' exonuclease [Mycobacterium sp. JLS]
Length=428

 Score =  522 bits (1344),  Expect = 5e-146, Method: Compositional matrix adjust.
 Identities = 286/410 (70%), Positives = 329/410 (81%), Gaps = 8/410 (1%)

Query  15   GTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQ  74
            GT++   PLL PA G+PDL VT  EI AAAELL  G GPFA+DAERASGFRYS RAYL+Q
Sbjct  21   GTDTGAVPLLTPADGVPDLAVTTDEILAAAELLAGGHGPFAIDAERASGFRYSNRAYLVQ  80

Query  75   IRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYD  134
            IRR  AGTVLIDPV+HG DP  V+APVA+VL T+EW+LH+ADQDLPCLAE+GMRPP LYD
Sbjct  81   IRREGAGTVLIDPVNHGEDPTMVMAPVADVLDTDEWVLHAADQDLPCLAELGMRPPKLYD  140

Query  135  TELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELR  194
            TELAGRLAG  RVNLA MV  LLGL L KGHGAADWSKRPLP  WLNYAALDVE+L+ELR
Sbjct  141  TELAGRLAGLARVNLATMVSELLGLQLMKGHGAADWSKRPLPDDWLNYAALDVEVLLELR  200

Query  195  AAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRE  254
             A++ VL +QGKTDWA QEFEHLR++E+ P     R+DRWRRTSGIHKV + R LAAVRE
Sbjct  201  DAVAAVLDDQGKTDWAIQEFEHLRTYEAAP----TRRDRWRRTSGIHKVRNPRALAAVRE  256

Query  255  LWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAA  314
            LWT RD IA+RRDIAP RILPD+AII+AA ADP SV+ L ALPVFGG  QRRSA VW  A
Sbjct  257  LWTTRDHIARRRDIAPGRILPDAAIINAATADPDSVEKLTALPVFGGTRQRRSAQVWLDA  316

Query  315  LAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVS  374
            L  AR + DPP+ AEP NGPPPP RW RRKP AAARL+AARA L+ +S+RV VP+ENLV+
Sbjct  317  LDRARHNTDPPDSAEPPNGPPPPSRWARRKPEAAARLEAARAGLSALSERVAVPSENLVT  376

Query  375  PDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            P++VRRLCW+W+ ++    D  AAVE +L     R WQ +LVVP+LTAAL
Sbjct  377  PEVVRRLCWDWQPVT----DIAAAVEEFLVAAGVRPWQRDLVVPVLTAAL  422


>gi|333991066|ref|YP_004523680.1| hypothetical protein JDM601_2426 [Mycobacterium sp. JDM601]
 gi|333487034|gb|AEF36426.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=420

 Score =  508 bits (1309),  Expect = 5e-142, Method: Compositional matrix adjust.
 Identities = 301/416 (73%), Positives = 342/416 (83%), Gaps = 7/416 (1%)

Query  17   ESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIR  76
            E EPTPL  PA G+P++ VT  +I AAAE L  G GPFAVDAERASGFRYS RAYLIQIR
Sbjct  12   EPEPTPLPHPADGVPEVSVTTRQIGAAAEKLAGGHGPFAVDAERASGFRYSNRAYLIQIR  71

Query  77   RAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTE  136
            RA AGTVLIDPV  G DP  +L PVAEVL  +EWILH+ADQDL CLAEVGM P ALYDTE
Sbjct  72   RAGAGTVLIDPVGAGSDPAALLRPVAEVLDDDEWILHAADQDLACLAEVGMWPKALYDTE  131

Query  137  LAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAA  196
            LAGRLAGFDRVNLAAMV+RLLGLGL KGHGAADWSKRPLP+ WLNYAALDVE+LIELR A
Sbjct  132  LAGRLAGFDRVNLAAMVQRLLGLGLAKGHGAADWSKRPLPAEWLNYAALDVEVLIELREA  191

Query  197  ISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELW  256
            I+ VL+ QGK+DWAAQEF HLRS +      + R+DRWRRTSGIHKV DRRGLAAVRELW
Sbjct  192  IAEVLSGQGKSDWAAQEFSHLRSTDF---ITSTRRDRWRRTSGIHKVRDRRGLAAVRELW  248

Query  257  TARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALA  316
            T RDRIA+RRDIAP RILPD+AII AA+ADP +VD+L+ALPVFGG  QRRSAA W AALA
Sbjct  249  TVRDRIAERRDIAPGRILPDAAIIAAAVADPTTVDELLALPVFGGPKQRRSAATWLAALA  308

Query  317  AARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPD  376
            AAR++P+PP+ AEP +GPPPP RW RRKP AAARL+AAR AL ++S++V VPTENL+SPD
Sbjct  309  AARDNPEPPDSAEPPSGPPPPSRWSRRKPEAAARLEAARGALGQLSEQVSVPTENLLSPD  368

Query  377  LVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGA  432
            L+RRLCW+W   S ++PDP  A+E +L TG AR WQ +L VP+L  AL GA  AG 
Sbjct  369  LLRRLCWDW---SAATPDPAVAIEEFLNTGGARPWQRQLTVPLLAQAL-GATVAGG  420


>gi|289762852|ref|ZP_06522230.1| conserved alanine rich protein [Mycobacterium tuberculosis GM 
1503]
 gi|289710358|gb|EFD74374.1| conserved alanine rich protein [Mycobacterium tuberculosis GM 
1503]
Length=259

 Score =  501 bits (1289),  Expect = 1e-139, Method: Compositional matrix adjust.
 Identities = 258/259 (99%), Positives = 259/259 (100%), Gaps = 0/259 (0%)

Query  180  LNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSG  239
            +NYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSG
Sbjct  1    MNYAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSG  60

Query  240  IHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVF  299
            IHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVF
Sbjct  61   IHKVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVF  120

Query  300  GGRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALT  359
            GGRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALT
Sbjct  121  GGRNQRRSAAVWWAALAAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALT  180

Query  360  EVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPI  419
            EVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPI
Sbjct  181  EVSQRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPI  240

Query  420  LTAALTGAPDAGAQGDDGS  438
            LTAALTGAPDAGAQGDDGS
Sbjct  241  LTAALTGAPDAGAQGDDGS  259


>gi|169630071|ref|YP_001703720.1| hypothetical protein MAB_2988 [Mycobacterium abscessus ATCC 19977]
 gi|169242038|emb|CAM63066.1| Conserved hypothetical protein (putative exonuclease) [Mycobacterium 
abscessus]
Length=400

 Score =  481 bits (1237),  Expect = 1e-133, Method: Compositional matrix adjust.
 Identities = 252/406 (63%), Positives = 301/406 (75%), Gaps = 16/406 (3%)

Query  19   EPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRA  78
            EPTPLLRPA G+P +  +  EI AAA+ L  G GPFAVDAERASGFRYS RAYLIQIRR 
Sbjct  9    EPTPLLRPAEGVPPITASTDEIRAAAQRLISGTGPFAVDAERASGFRYSNRAYLIQIRRR  68

Query  79   EAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELA  138
             AGTVL+DP +  G     L P+ + L  +EWILH+ADQDLPCLAE+ M+PP+LYDTELA
Sbjct  69   GAGTVLLDPTNVPGS----LGPIVDALGADEWILHAADQDLPCLAELAMKPPSLYDTELA  124

Query  139  GRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAIS  198
            GRLAGF++VNLA+MV RLLGLGL KGHGAADWSKRPLP  WLNYAALDVE+L+ELR  I+
Sbjct  125  GRLAGFEKVNLASMVHRLLGLGLAKGHGAADWSKRPLPDDWLNYAALDVEVLVELRDKIA  184

Query  199  RVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTA  258
             VLAEQGKT+WA QEFEHL    +  P  A R+D WRRTSGIHKV     LAAVRELW +
Sbjct  185  EVLAEQGKTEWARQEFEHL----AHTPVPATRRDNWRRTSGIHKVRKPGQLAAVRELWLS  240

Query  259  RDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAA  318
            RD +A+ RD+AP R LPDSAI++AA+ADPK+  +L+ALPVFGG  Q++ A  W AALA A
Sbjct  241  RDELARARDVAPGRTLPDSAIVEAALADPKTRAELIALPVFGGPRQKQQADRWLAALAKA  300

Query  319  RESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDLV  378
            R    PP + EP  GPPP  RW RRKP A ARL+AAR AL  +S+++ VP EN+V+P++V
Sbjct  301  RSGTAPPPVNEPTTGPPPVSRWSRRKPEAYARLEAARTALAALSEQISVPVENIVTPEIV  360

Query  379  RRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            RR+CW+W        D    V+  L    AR WQ +L VP+LT AL
Sbjct  361  RRICWDW--------DGHGDVDEQLAGHGARPWQRQLTVPLLTEAL  398


>gi|325672651|ref|ZP_08152347.1| ribonuclease III [Rhodococcus equi ATCC 33707]
 gi|325556528|gb|EGD26194.1| ribonuclease III [Rhodococcus equi ATCC 33707]
Length=413

 Score =  440 bits (1131),  Expect = 3e-121, Method: Compositional matrix adjust.
 Identities = 247/411 (61%), Positives = 298/411 (73%), Gaps = 13/411 (3%)

Query  18   SEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRR  77
            + P PLL PA G+P +  T   +  AAE L  G GP AVDAERASGFRYS RAYL+Q+RR
Sbjct  8    TTPVPLLVPADGVPPVIETAAGVRDAAERLAAGTGPLAVDAERASGFRYSSRAYLVQLRR  67

Query  78   AEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTEL  137
            A AG+ L+DP+    D    L P+ + ++  EW+LHSADQDLPCLAE+G+ P AL+DTEL
Sbjct  68   AGAGSFLLDPIPTAED----LEPLRDAINGLEWVLHSADQDLPCLAELGLEPAALFDTEL  123

Query  138  AGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAI  197
            AGRLAGF+RV LAA+VER LGL L KGHGAADWS RPLP AWLNYAALDVE+L+ELR A+
Sbjct  124  AGRLAGFERVGLAAIVERTLGLELRKGHGAADWSTRPLPDAWLNYAALDVEVLLELREAM  183

Query  198  SRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWT  257
            +  LA QGKT+WAAQEFEH+R       P   + DRWRRTS IH +   R LAAVRELWT
Sbjct  184  ATELAAQGKTEWAAQEFEHVRLAG----PPQPKPDRWRRTSQIHSLKSPRQLAAVRELWT  239

Query  258  ARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAA  317
             RD IA++RDI+P RILPDSAI+ AA ADPKS+D L ALPVFGG  QRRS+ +W  AL  
Sbjct  240  TRDEIARKRDISPSRILPDSAIVTAASADPKSIDTLRALPVFGGPRQRRSSRIWLGALER  299

Query  318  ARESP--DPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSP  375
            AR  P  + P + +P  GPPPP RW +R P AAARL  A+  + E+S+RV VP ENL+SP
Sbjct  300  ARALPQNELPPVNQPFTGPPPPSRWTKRDPDAAARLATAKTGIAELSERVGVPVENLLSP  359

Query  376  DLVRRLCWEWEDISQSSP--DPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            DLVRR+CWE    + ++P  +  AAV+A L  G AR WQ +L+VPIL  AL
Sbjct  360  DLVRRVCWE-PPATPTTPDAEAAAAVDAALAAGGARPWQRDLMVPILVEAL  409


>gi|312139461|ref|YP_004006797.1| rnase d [Rhodococcus equi 103S]
 gi|311888800|emb|CBH48112.1| putative RNase D [Rhodococcus equi 103S]
Length=445

 Score =  439 bits (1129),  Expect = 4e-121, Method: Compositional matrix adjust.
 Identities = 247/411 (61%), Positives = 298/411 (73%), Gaps = 13/411 (3%)

Query  18   SEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRR  77
            + P PLL PA G+P +  T   +  AAE L  G GP AVDAERASGFRYS RAYL+Q+RR
Sbjct  40   TTPVPLLVPADGVPPVIETAAGVRDAAERLAAGTGPLAVDAERASGFRYSSRAYLVQLRR  99

Query  78   AEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTEL  137
            A AG+ L+DP+    D    L P+ + ++  EW+LHSADQDLPCLAE+G+ P AL+DTEL
Sbjct  100  AGAGSFLLDPIPTAED----LEPLRDAINGLEWVLHSADQDLPCLAELGLEPAALFDTEL  155

Query  138  AGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAI  197
            AGRLAGF+RV LAA+VER LGL L KGHGAADWS RPLP AWLNYAALDVE+L+ELR A+
Sbjct  156  AGRLAGFERVGLAAIVERTLGLELRKGHGAADWSTRPLPDAWLNYAALDVEVLLELREAM  215

Query  198  SRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWT  257
            +  LA QGKT+WAAQEFEH+R       P   + DRWRRTS IH +   R LAAVRELWT
Sbjct  216  ATELAAQGKTEWAAQEFEHVRLAG----PPQPKPDRWRRTSQIHSLKSPRQLAAVRELWT  271

Query  258  ARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAA  317
             RD IA++RDI+P RILPDSAI+ AA ADPKS+D L ALPVFGG  QRRS+ +W  AL  
Sbjct  272  TRDEIARKRDISPSRILPDSAIVTAASADPKSIDTLRALPVFGGPRQRRSSRIWLGALER  331

Query  318  ARESP--DPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSP  375
            AR  P  + P + +P  GPPPP RW +R P AAARL  A+  + E+S+RV VP ENL+SP
Sbjct  332  ARALPQNELPPVNQPFTGPPPPSRWAKRDPDAAARLATAKTGIAELSERVGVPVENLLSP  391

Query  376  DLVRRLCWEWEDISQSSP--DPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            DLVRR+CWE    + ++P  +  AAV+A L  G AR WQ +L+VPIL  AL
Sbjct  392  DLVRRVCWE-PPATPTTPDAEAAAAVDAALAAGGARPWQRDLMVPILVEAL  441


>gi|111023812|ref|YP_706784.1| ribonuclease III [Rhodococcus jostii RHA1]
 gi|110823342|gb|ABG98626.1| probable ribonuclease III [Rhodococcus jostii RHA1]
Length=429

 Score =  423 bits (1087),  Expect = 4e-116, Method: Compositional matrix adjust.
 Identities = 246/432 (57%), Positives = 295/432 (69%), Gaps = 16/432 (3%)

Query  11   AESEGTESEP----TPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRY  66
            A S G   EP     PLL P  G+PD+  T   +A AA  L  G GP AVDAERASGFRY
Sbjct  8    ASSPGPAEEPGRQIVPLLAPRDGVPDVVTTAEGVAKAAAALSEGTGPLAVDAERASGFRY  67

Query  67   SGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVG  126
            S RAYL+Q+RR  AGTVL+DP+    D    LAP+AEV++  EWILHSADQDLP LAE+G
Sbjct  68   SARAYLVQLRREGAGTVLLDPIPTAAD----LAPLAEVINPLEWILHSADQDLPGLAEIG  123

Query  127  MRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALD  186
            + P  L+DTELAGRLAGF+RV LAA+VER LGL L KGHGAADWSKRPLP +WLNYAALD
Sbjct  124  LAPATLFDTELAGRLAGFERVGLAAIVERTLGLELRKGHGAADWSKRPLPDSWLNYAALD  183

Query  187  VELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDR  246
            VE+L+ELR  ++  L EQGK++WAAQEFEH+R     P P A   DRWRRTS I  +  +
Sbjct  184  VEVLVELRNVMAAELDEQGKSEWAAQEFEHIR-LAGPPKPKA---DRWRRTSHITSLKTQ  239

Query  247  RGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRR  306
            R LAA R LW AR+ +A++RD++P R+LPD+AIIDAA  DP+S++ L ALPVFGG  QRR
Sbjct  240  RQLAAARSLWQAREDLARKRDVSPSRVLPDAAIIDAATKDPRSIEALRALPVFGGPRQRR  299

Query  307  SAAVWWAALAAARESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQR  364
             + +W  AL  AR  PD   P    P  GPPP  RW R  P AA RL AARAAL  +   
Sbjct  300  HSRIWLQALEDARALPDTELPPKTPPFTGPPPASRWARHDPDAAERLTAARAALAALGTE  359

Query  365  VRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            V VP ENLV+P+LVRRLCW+W   +    D  +A++  L  G AR WQ  L VP+L +AL
Sbjct  360  VSVPVENLVTPELVRRLCWDWS--APEGGDVESAIDRVLDAGGARPWQRMLTVPVLASAL  417

Query  425  TGAPDAGAQGDD  436
              A +    GDD
Sbjct  418  LSAAEQKGSGDD  429


>gi|229491276|ref|ZP_04385102.1| ribonuclease D [Rhodococcus erythropolis SK121]
 gi|229321815|gb|EEN87610.1| ribonuclease D [Rhodococcus erythropolis SK121]
Length=431

 Score =  421 bits (1081),  Expect = 2e-115, Method: Compositional matrix adjust.
 Identities = 235/416 (57%), Positives = 290/416 (70%), Gaps = 19/416 (4%)

Query  18   SEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRR  77
            S+  PLL P  G+PD+  T   +A AA  L  G GP AVDAERASGFRYS RAYLIQ+RR
Sbjct  15   SDVVPLLVPRDGVPDVITTAAGVADAAAALASGHGPLAVDAERASGFRYSARAYLIQLRR  74

Query  78   AEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTEL  137
              AG+ L+DP+    D    L P+AEV++  +W+LHSADQDLP LAE+G+ P  L+DTEL
Sbjct  75   EGAGSFLLDPIPTAQD----LQPLAEVINPLQWVLHSADQDLPGLAELGLTPAELFDTEL  130

Query  138  AGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAI  197
            AGRLAGF+RV LAA+VER L + L KGHGAADWS RPLP AWLNYAALDVE+L+ELR A+
Sbjct  131  AGRLAGFERVGLAAIVERTLRVELRKGHGAADWSTRPLPDAWLNYAALDVEVLLELRDAM  190

Query  198  SRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWT  257
               L  QGK +WA +EFE++R     P P   + DRWRRTS I  +   R LAAVR LW 
Sbjct  191  EAELESQGKLEWAKEEFEYIR-LAGPPKP---KPDRWRRTSHITSLKTTRQLAAVRALWQ  246

Query  258  ARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAA  317
            AR+ +A++RD++P R+LPDSAIIDAA+ DP+S+D L +LPVFGG  QRR + +W  AL A
Sbjct  247  AREDLARKRDVSPSRVLPDSAIIDAALKDPRSLDALRSLPVFGGPRQRRYSRIWMDALEA  306

Query  318  ARESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSP  375
            AR  PD   P    P  GPP  GRW R+ PAAA RL AARAAL+++S+ V VP ENL+ P
Sbjct  307  ARRLPDSELPPKTPPIVGPPAAGRWARQDPAAADRLTAARAALSDLSKEVSVPVENLLQP  366

Query  376  DLVRRLCWEWE-----DISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTG  426
            DLVRRLCW+W+     DI++      +A+E  L +G AR WQ  L VP+L  AL  
Sbjct  367  DLVRRLCWDWKLEPDSDIAEVE----SAIETKLTSGGARGWQRTLTVPVLAEALNS  418


>gi|226306331|ref|YP_002766291.1| ribonuclease D [Rhodococcus erythropolis PR4]
 gi|226185448|dbj|BAH33552.1| putative ribonuclease D [Rhodococcus erythropolis PR4]
Length=429

 Score =  420 bits (1079),  Expect = 3e-115, Method: Compositional matrix adjust.
 Identities = 236/417 (57%), Positives = 291/417 (70%), Gaps = 21/417 (5%)

Query  18   SEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRR  77
            S+  PLL P  G+PD+  T   +A AA  L  G GP AVDAERASGFRYS RAYLIQ+RR
Sbjct  13   SDVVPLLVPRDGVPDVITTAAGVADAAAALASGHGPLAVDAERASGFRYSARAYLIQLRR  72

Query  78   AEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTEL  137
              AG+ L+DP+    D    L P+AE ++  +W+LHSADQDLP LAE+G+ P  L+DTEL
Sbjct  73   EGAGSFLLDPIPTAQD----LQPLAEAINPLQWVLHSADQDLPGLAELGLTPAELFDTEL  128

Query  138  AGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAI  197
            AGRLAGF+RV LAA+VER L + L KGHGAADWS RPLP AWLNYAALDVE+L+ELR A+
Sbjct  129  AGRLAGFERVGLAAIVERTLRVELRKGHGAADWSTRPLPDAWLNYAALDVEVLLELRDAM  188

Query  198  SRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWT  257
               L  QGK +WA +EFE++R     P P   + DRWRRTS I  +   R LAAVR LW 
Sbjct  189  EAELESQGKLEWAKEEFEYIR-LAGPPKP---KPDRWRRTSHITSLKTTRQLAAVRALWQ  244

Query  258  ARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAA  317
            AR+ +A++RD++P R+LPDSAIIDAA+ DP+S+D L +LPVFGG  QRR + VW  AL A
Sbjct  245  AREDLARKRDVSPSRVLPDSAIIDAALKDPQSLDALRSLPVFGGPRQRRYSRVWMDALEA  304

Query  318  ARESPD---PPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVS  374
            AR  PD   PP+   P  GPP  GRW R+ PAAA RL AARAAL+++S+ V VP ENL+ 
Sbjct  305  ARRLPDSELPPKTP-PIVGPPAAGRWARQDPAAADRLTAARAALSDLSKEVSVPVENLLQ  363

Query  375  PDLVRRLCWEWE-----DISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTG  426
            PDLVRRLCW+W+     DI++      +A+E  L +G AR WQ  L VP+L  AL  
Sbjct  364  PDLVRRLCWDWKLEPDSDITEVE----SAIETKLTSGGARGWQRTLTVPVLAEALNS  416


>gi|54025710|ref|YP_119952.1| putative RNase D [Nocardia farcinica IFM 10152]
 gi|54017218|dbj|BAD58588.1| putative RNase D [Nocardia farcinica IFM 10152]
Length=424

 Score =  419 bits (1076),  Expect = 6e-115, Method: Compositional matrix adjust.
 Identities = 252/418 (61%), Positives = 296/418 (71%), Gaps = 15/418 (3%)

Query  15   GTESEPT--PLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYL  72
            G E  P+  PLL P  G+P +  T  E+AAAA  +  G GP AVDAERASGFRYS RAYL
Sbjct  10   GIEDTPSAEPLLAPVDGVPPVLATAAEVAAAAARIAAGTGPLAVDAERASGFRYSARAYL  69

Query  73   IQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPAL  132
            IQ+RRA AGT L+DP+         L P+AE ++  EW+LHSADQDLP LAE+G+RP  L
Sbjct  70   IQLRRAGAGTFLVDPIPVA----DALGPLAEAINDLEWVLHSADQDLPGLAELGLRPARL  125

Query  133  YDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIE  192
            +DTEL GRLAGF+RV LAAMVERLLG  L KGHGAADWS RPLP+ WLNYAALDVELL+E
Sbjct  126  FDTELGGRLAGFERVGLAAMVERLLGRTLRKGHGAADWSTRPLPAEWLNYAALDVELLLE  185

Query  193  LRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAV  252
            LR A++  L  QGK+DWAAQEFEH+R+ E    P A + DRWRRTSGIH +   R LA V
Sbjct  186  LRDAVAAELQRQGKSDWAAQEFEHVRTTE----PPAPKADRWRRTSGIHTLRKPRQLAIV  241

Query  253  RELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWW  312
            RELWT RD +A+ RDIAP RILPD AI+ AA ADP+S+  L ALPVFGG  QRR +  W 
Sbjct  242  RELWTTRDTLARSRDIAPARILPDGAIVAAAAADPRSIAQLRALPVFGGPRQRRYSREWL  301

Query  313  AALAAARESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTE  370
            AA+  AR  PD   P + +P +GPPPP RW RR P AAARL  ARAA+ E+S    VP E
Sbjct  302  AAVDRARALPDDALPPLTQPFDGPPPPNRWERRDPVAAARLTRARAAMAELSTEHAVPVE  361

Query  371  NLVSPDLVRRLCWEWEDISQSSPDP---IAAVEAYLRTGQARAWQLELVVPILTAALT  425
            NL+SPDLVRRLCW+         DP    AA++ +L++G AR WQ EL VP LT ALT
Sbjct  362  NLLSPDLVRRLCWDGLPDYDRVGDPGDLAAAIDGFLKSGGARPWQRELTVPRLTLALT  419


>gi|226366248|ref|YP_002784031.1| ribonuclease [Rhodococcus opacus B4]
 gi|226244738|dbj|BAH55086.1| putative ribonuclease [Rhodococcus opacus B4]
Length=428

 Score =  418 bits (1074),  Expect = 1e-114, Method: Compositional matrix adjust.
 Identities = 246/422 (59%), Positives = 291/422 (69%), Gaps = 21/422 (4%)

Query  21   TPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAEA  80
             PLL P  G+PD+  T   +A AA  L  G GP AVDAERASGFRYS RAYL+Q+RR  A
Sbjct  22   VPLLAPRDGVPDVVTTAEGVAKAAAALSEGTGPLAVDAERASGFRYSARAYLVQLRREGA  81

Query  81   GTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAGR  140
            GTVL+DP+    D    LAP+AEV++  EWILHSADQDLP LAE+G+ P  L+DTELAGR
Sbjct  82   GTVLLDPIPTAAD----LAPLAEVINPLEWILHSADQDLPGLAEIGLAPATLFDTELAGR  137

Query  141  LAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISRV  200
            LAGF+RV LAA+VER LG  L KGHGAADWSKRPLP  WLNYAALDVE+L+ELR A++  
Sbjct  138  LAGFERVGLAAIVERTLGFELRKGHGAADWSKRPLPDTWLNYAALDVEVLVELRNAMAAE  197

Query  201  LAEQGKTDWAAQEFEHLR-SFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTAR  259
            L EQGK+DWAAQEFEH+R +   RP P     DRWRRTS I  +  +R LAAVR LW AR
Sbjct  198  LGEQGKSDWAAQEFEHIRLAGPPRPKP-----DRWRRTSHITSLKTQRQLAAVRSLWQAR  252

Query  260  DRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAAR  319
            + +A++RD++P R+LPDSAIIDAA  DP+S++ L ALPVFGG  QRR + +W  AL  AR
Sbjct  253  EDLARKRDVSPSRVLPDSAIIDAATKDPRSIEALRALPVFGGPRQRRHSRIWLQALEDAR  312

Query  320  ESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDL  377
              PD   P    P  GPPP  RW R  P AA RL AARAAL  +   V VP ENLV+P+L
Sbjct  313  ALPDSELPPKTPPFTGPPPASRWARHDPDAAERLTAARAALAALGAEVSVPVENLVTPEL  372

Query  378  VRRLCWEW---EDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDAGAQG  434
            VRRLCW+W   ED ++      AA++  L  G AR WQ  L VP L  AL  A +    G
Sbjct  373  VRRLCWDWSVPEDGAE------AAIDRVLDAGGARPWQRMLTVPRLATALRAAAEQKGAG  426

Query  435  DD  436
            DD
Sbjct  427  DD  428


>gi|326384419|ref|ZP_08206099.1| 3'-5' exonuclease [Gordonia neofelifaecis NRRL B-59395]
 gi|326196764|gb|EGD53958.1| 3'-5' exonuclease [Gordonia neofelifaecis NRRL B-59395]
Length=407

 Score =  386 bits (992),  Expect = 3e-105, Method: Compositional matrix adjust.
 Identities = 216/419 (52%), Positives = 272/419 (65%), Gaps = 22/419 (5%)

Query  10   AAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGR  69
            A  S+    E TPL RP  G+P +     E A AAEL+ RG GP AVD ERASG+RYS R
Sbjct  6    AGPSDQGAPEITPLTRPHDGVPTVLSRPDEFAEAAELIGRGTGPIAVDTERASGYRYSQR  65

Query  70   AYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRP  129
            AYL+Q++RA +G+ LIDP+SH       L+P+ + L   EWILH+ADQDLPCL E+G  P
Sbjct  66   AYLVQLKRAGSGSFLIDPISHP----DALSPLIDALDGPEWILHAADQDLPCLRELGFTP  121

Query  130  PALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVEL  189
              L+DTELAGRL    +VNLAAMV   L LGL KGHGAADWS+RPLP  WLNYAALDVE+
Sbjct  122  TTLFDTELAGRLLNIPKVNLAAMVAEFLHLGLAKGHGAADWSRRPLPDDWLNYAALDVEV  181

Query  190  LIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGL  249
            L+ELR A++  L+E G+ +WAAQEF ++ +     PP+A + DRWRRTS IH +   R L
Sbjct  182  LVELRDAVADALSEAGRDEWAAQEFAYVLAR----PPSAPKPDRWRRTSNIHDLRSARQL  237

Query  250  AAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAA  309
            A VRELWTAR+ +A  RD+AP R+LPDSAII AA A+P     L  LPVFGG  QRR A 
Sbjct  238  AVVRELWTAREELAALRDVAPGRVLPDSAIITAATANPVDGKALTRLPVFGGPRQRRQAD  297

Query  310  VWWAALAAARESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRV  367
             W  A++ A+  P+   P    P  GPPP  RW +R P AAAR +A R  +  +++ + +
Sbjct  298  RWMRAISTAQRLPESELPSKKSPQVGPPPYNRWEQRNPEAAARANAVRPVVRTIAEEIGI  357

Query  368  PTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEA--YLRTGQARAWQLELVVPILTAAL  424
            P ENL++PDL+R LCW          D +A  +A  +L    AR WQ ELV   +  AL
Sbjct  358  PQENLLAPDLLRNLCW----------DGLAGDDAGSWLAAHGARPWQRELVAEPIDDAL  406


>gi|294815677|ref|ZP_06774320.1| putative ribonuclease D [Streptomyces clavuligerus ATCC 27064]
 gi|326444024|ref|ZP_08218758.1| ribonuclease D [Streptomyces clavuligerus ATCC 27064]
 gi|294328276|gb|EFG09919.1| putative ribonuclease D [Streptomyces clavuligerus ATCC 27064]
Length=428

 Score =  383 bits (984),  Expect = 3e-104, Method: Compositional matrix adjust.
 Identities = 225/414 (55%), Positives = 275/414 (67%), Gaps = 17/414 (4%)

Query  17   ESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIR  76
            E+ PTPLL P  GIP +      +AA       G GP AVDAERASG+RY  RAYL+Q+R
Sbjct  29   EAPPTPLLEPREGIPAVVADADALAAVTAAFGAGSGPVAVDAERASGYRYGQRAYLVQLR  88

Query  77   RAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTE  136
            RA AG+ LIDPV+        L+P+ E L   EWILH+A QDLPCL ++GM P  L+DTE
Sbjct  89   RAGAGSALIDPVA-----CPDLSPLGEALDGAEWILHAATQDLPCLRDIGMAPALLFDTE  143

Query  137  LAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAA  196
            LAGRLAGF RV L AMVE +LG  L KGH A DWS RPLP  WL YAALDVELLI+LR A
Sbjct  144  LAGRLAGFPRVGLGAMVESVLGYALEKGHSAVDWSTRPLPEPWLRYAALDVELLIDLRDA  203

Query  197  ISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELW  256
            +   LAEQGK +WA QEF  + +        A R+D WRRTSG+HKV  RR +A VRELW
Sbjct  204  LEEELAEQGKLEWARQEFAAIAAAPP----PAPRKDPWRRTSGMHKVRRRRQMAVVRELW  259

Query  257  TARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAAL-  315
            TARD +AQRRD++P ++L DSAII+AA+A P +V  L ALP FG R  RR    W +A+ 
Sbjct  260  TARDAVAQRRDVSPGKVLSDSAIIEAALAVPPTVQALTALPGFGHRMGRRQLEQWQSAVD  319

Query  316  -AAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVS  374
             A A    + P+  +P NGPPPP  W  + P AAARL AAR A++E+++R+ +P ENL++
Sbjct  320  RAKALSESELPQPGQPLNGPPPPRAWADKDPVAAARLSAARTAVSELAERLNLPQENLIT  379

Query  375  PDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL-TGA  427
            PD VRR+CWE       +    AAV A L    AR WQ+ELV P+L  AL TGA
Sbjct  380  PDTVRRVCWE-----PPAERSEAAVAAALAGFGARPWQIELVAPLLAQALATGA  428


>gi|257056403|ref|YP_003134235.1| ribonuclease D [Saccharomonospora viridis DSM 43017]
 gi|256586275|gb|ACU97408.1| ribonuclease D [Saccharomonospora viridis DSM 43017]
Length=413

 Score =  381 bits (979),  Expect = 1e-103, Method: Compositional matrix adjust.
 Identities = 233/422 (56%), Positives = 281/422 (67%), Gaps = 21/422 (4%)

Query  9    GAAESEGT--ESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRY  66
             A  S GT  +S P PL  PA G PD+      + AA E L  G G  AVD ERASG+RY
Sbjct  3    NADHSSGTPGDSAPLPLTEPAEGTPDVIADPDTLRAACERLAEGSGALAVDTERASGYRY  62

Query  67   SGRAYLIQIRRAEAGTVLIDPVSHGGDPL-TVLAPVAEVLSTNEWILHSADQDLPCLAEV  125
              +AYLIQIRR  AGT LIDP+     PL     P+AEV++  EW+LH+A QDLPCLAE+
Sbjct  63   WPKAYLIQIRREGAGTFLIDPI-----PLRDHFTPLAEVMNQVEWVLHAASQDLPCLAEL  117

Query  126  GMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAAL  185
            G+ PP+L+DTELAGRLAG+ RV L  +VE LLG  L KGH AADWS+RPLP  WLNYAAL
Sbjct  118  GLHPPSLFDTELAGRLAGYQRVALGTLVESLLGYQLEKGHSAADWSRRPLPLDWLNYAAL  177

Query  186  DVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHD  245
            DVELL+ LR  +   LA  GK +WA QEFE +R+  ++PP  A R + WRRTSGIHKV  
Sbjct  178  DVELLLPLREKLEEELAASGKLEWARQEFEAVRT--AKPP--APRAEPWRRTSGIHKVRT  233

Query  246  RRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQR  305
             RGLAAVR LW ARD +A+RRD AP RILPDSAII+A +AD ++  DL  LPVF GR QR
Sbjct  234  ARGLAAVRALWEARDELARRRDRAPGRILPDSAIINAVLADARTSADLEKLPVFRGRVQR  293

Query  306  RSAAVWWAALAAARESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQ  363
            + A  W   L  AR  P+   P  A   +GPPPP RW  + P AAARL AA+AAL ++++
Sbjct  294  KQATHWLRQLQRARTLPESELPSTAVTYDGPPPPNRWAEKNPDAAARLAAAKAALADIAE  353

Query  364  RVRVPTENLVSPDLVRRLCWE-WEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTA  422
            R R+P ENL+ P+LVRRLCW+  ED S+ S      V   L  G AR WQ+EL    L+ 
Sbjct  354  RNRLPVENLLLPELVRRLCWQPPEDTSRES------VATALAEGGARPWQIELTAAELSK  407

Query  423  AL  424
            AL
Sbjct  408  AL  409


>gi|343924647|ref|ZP_08764191.1| ribonuclease D [Gordonia alkanivorans NBRC 16433]
 gi|343765447|dbj|GAA11117.1| ribonuclease D [Gordonia alkanivorans NBRC 16433]
Length=428

 Score =  381 bits (979),  Expect = 1e-103, Method: Compositional matrix adjust.
 Identities = 227/408 (56%), Positives = 277/408 (68%), Gaps = 14/408 (3%)

Query  19   EPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRA  78
            E  PLL PAGG+P +  T  E A AA  L  G GP AVD ERASG+RYS RAYLIQI+R 
Sbjct  21   EVEPLLAPAGGVPPVLSTAAEFADAARALAAGEGPIAVDTERASGYRYSQRAYLIQIKRR  80

Query  79   EAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELA  138
             +G+ L+DP++   DP   LAPV + L   EW+LH+ADQDLPCL E+G     LYDTELA
Sbjct  81   GSGSFLLDPIA---DP-EALAPVIDALRGPEWVLHAADQDLPCLRELGFECVELYDTELA  136

Query  139  GRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAIS  198
            GRL G  +VNLAAMV + LGLGL KGHGAADWS+RPLP  WLNYAALDVE+L+ELR A+ 
Sbjct  137  GRLLGLAKVNLAAMVAQFLGLGLLKGHGAADWSRRPLPDDWLNYAALDVEVLVELRDAMD  196

Query  199  RVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTA  258
              LAE GK  WA +EF ++ S     PPA  R DRWR+TS IH V   R LAAVRELWTA
Sbjct  197  AALAESGKDGWAREEFAYVLSR----PPAPPRTDRWRKTSNIHTVKSARALAAVRELWTA  252

Query  259  RDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAA  318
            R+ +A+RRD+AP R+LPD+AI++AA  DPKS  +L  LPVFGG  QRR A +W +AL  A
Sbjct  253  REELAERRDVAPGRVLPDTAIVNAATVDPKSNSELTRLPVFGGPRQRRQAGIWLSALQRA  312

Query  319  RESPDPPEIAEPANGP--PPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPD  376
            RE PD    A    GP  PP  RW +R P AAAR+   R AL EV++   +P EN+++PD
Sbjct  313  RELPDSELPARKTTGPGLPPVSRWEQRNPEAAARMQKVRPALKEVAEHHTLPVENILAPD  372

Query  377  LVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            +VR+LCW+      + P    A++A+L    AR WQ +L V  LT AL
Sbjct  373  VVRQLCWD----GLAEPVTTEAMDAHLTAAGARPWQRQLSVDALTEAL  416


>gi|238063529|ref|ZP_04608238.1| 3'-5' exonuclease [Micromonospora sp. ATCC 39149]
 gi|237885340|gb|EEP74168.1| 3'-5' exonuclease [Micromonospora sp. ATCC 39149]
Length=442

 Score =  377 bits (967),  Expect = 3e-102, Method: Compositional matrix adjust.
 Identities = 227/433 (53%), Positives = 273/433 (64%), Gaps = 19/433 (4%)

Query  2    CPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERA  61
             PEP  AG    E T   P PL  P  G P+   TV  +A        G GP A+DAERA
Sbjct  27   APEPVDAG---PEPTADGPVPLTAPREGTPEPVTTVAGLAEVVARFAAGTGPVALDAERA  83

Query  62   SGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPC  121
            SG+RYS RAYL+Q+RRA AGT LIDP+     PL  L+ +   ++  EW+LH+A QDLPC
Sbjct  84   SGYRYSQRAYLVQLRRAGAGTALIDPL-----PLPDLSSLDSAIADAEWVLHAASQDLPC  138

Query  122  LAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLN  181
            LAEVG+RP  L+DTELA RLAGF+RV LAA+ E+LLG  L K H AADWS RPLP +WL 
Sbjct  139  LAEVGLRPRRLFDTELAARLAGFERVGLAALTEQLLGFSLEKHHSAADWSSRPLPESWLT  198

Query  182  YAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIH  241
            YAALDVELL +LR A+   LA QGK+ WAA+EF  L    +RPP    R + WRRTSGIH
Sbjct  199  YAALDVELLTDLRDALDAELARQGKSAWAAEEFAALVHSGARPP--RVRAEPWRRTSGIH  256

Query  242  KVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGG  301
            +V   R  A VR LW ARD+IA RRD AP R+LPDSAI+ AA  DP+    L+ LP FGG
Sbjct  257  RVRGARAQARVRSLWYARDQIAARRDAAPGRVLPDSAIVAAAELDPRDEKTLLTLPGFGG  316

Query  302  RNQRRSAAVWWAALAAARESPDPPEIAEPA-NGPPPPGRWVRRKPAAAARLDAARAALTE  360
            R+ RR A  W AAL  AR+ P+      PA  GPPPP RW  R P AA RL   R  +  
Sbjct  317  RSVRRLARTWLAALDDARQLPEDALPVTPAVEGPPPPHRWAERDPVAAGRLARCREVVIR  376

Query  361  VSQRVRVPTENLVSPDLVRRLCWE-WEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPI  419
            V+    +P ENL++PD +RRL W   E++++      A V   LR   AR WQL L+VP 
Sbjct  377  VAGEHALPPENLIAPDSIRRLAWAPPEEVTE------ATVAETLRGFGAREWQLALLVPG  430

Query  420  LTAALTGAPDAGA  432
            LT ALT +P  GA
Sbjct  431  LTPALT-SPSPGA  442


>gi|297156498|gb|ADI06210.1| ribonuclease D [Streptomyces bingchenggensis BCW-1]
Length=424

 Score =  374 bits (961),  Expect = 1e-101, Method: Compositional matrix adjust.
 Identities = 214/418 (52%), Positives = 271/418 (65%), Gaps = 16/418 (3%)

Query  9    GAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSG  68
            G A  +   S P PLL P  GIP +      +A        G GP AVDAERASG+RY  
Sbjct  17   GGAPPDDLPSAPVPLLEPREGIPPVTADPDALAEVITAFAEGHGPVAVDAERASGYRYGQ  76

Query  69   RAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMR  128
            RAYL+Q+RRA AGT LIDPV   G P   L+ + + ++  EW+LH+A QDLPCL ++GM 
Sbjct  77   RAYLVQLRRAGAGTALIDPV---GCP--DLSGLGDAIADAEWVLHAATQDLPCLRDIGML  131

Query  129  PPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVE  188
            P  L+DTELAGRLAGF RV L AMVE +LG  L KGH A DWS RPLP  WL+YAALDVE
Sbjct  132  PGRLFDTELAGRLAGFARVGLGAMVENILGYALEKGHSAVDWSTRPLPDPWLHYAALDVE  191

Query  189  LLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRG  248
            LL++LR A+   L  QGK +WA QEF  + +       A  R+D WRRTSG+HKV  RR 
Sbjct  192  LLVDLRDALEEELTRQGKLNWAHQEFAAIAAAPP----APPRKDPWRRTSGMHKVRRRRQ  247

Query  249  LAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSA  308
            +A VRELWTARD+IAQRRD++P ++L D+AI++AA+A P +   L AL  FG R  RR  
Sbjct  248  MAVVRELWTARDKIAQRRDVSPGKVLGDAAIVEAALALPTTARALGALGGFGHRMGRRQL  307

Query  309  AVWWAALAAARESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVR  366
              W AA+  AR  P+   P+  +P  GPPPP  W  + P AAARL AAR A+T +++++ 
Sbjct  308  EQWQAAVDRARALPESELPQPGQPVAGPPPPRAWADKDPVAAARLSAARTAVTGLAEQLN  367

Query  367  VPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            +P ENL++PD VRRLC  WE  ++ + + +AAV   L    AR WQ+E   PIL  AL
Sbjct  368  LPQENLIAPDTVRRLC--WEPPAEVTAESVAAV---LHGYGARPWQIEQTTPILLTAL  420


>gi|333023774|ref|ZP_08451838.1| putative ribonuclease [Streptomyces sp. Tu6071]
 gi|332743626|gb|EGJ74067.1| putative ribonuclease [Streptomyces sp. Tu6071]
Length=431

 Score =  374 bits (959),  Expect = 2e-101, Method: Compositional matrix adjust.
 Identities = 220/407 (55%), Positives = 271/407 (67%), Gaps = 16/407 (3%)

Query  20   PTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAE  79
            P PLL P  GIP +      +A A      G GP AVDAERASG+RY  RAYL+Q+RRA 
Sbjct  34   PVPLLEPREGIPPVIADPESLATAVAAFASGSGPVAVDAERASGYRYGQRAYLVQLRRAG  93

Query  80   AGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAG  139
            AGT LIDPV+        L+ +   L+  EW LH+A QDLPCL E+GM P +L+DTELAG
Sbjct  94   AGTALIDPVA-----CPDLSGLGAALANAEWDLHAATQDLPCLREIGMVPHSLFDTELAG  148

Query  140  RLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISR  199
            RLAGF RV L AMVE +LG  L KGH A DWS RPLP  WL YAALDVELL++LR A+ +
Sbjct  149  RLAGFPRVGLGAMVENVLGYTLEKGHSAVDWSTRPLPEPWLRYAALDVELLVDLRDALEK  208

Query  200  VLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTAR  259
             L  QGK +WA +EF+ + S        A R+D WRRTSG+H+V  RR LA VRELWT R
Sbjct  209  ELERQGKLEWALEEFDAIASAPP----PAPRKDPWRRTSGMHRVRRRRQLAVVRELWTLR  264

Query  260  DRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAAR  319
            DRIA+RRD++P ++LPD+AI++AA+A P +V  L ALP FG R Q+R    W AA+  AR
Sbjct  265  DRIARRRDVSPGKVLPDAAIVEAALAVPVNVHALGALPAFGQRAQKRQLDQWQAAIDRAR  324

Query  320  ESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDL  377
            E P+   P+      GPPPP  W  R P AAARL AARA +  +++R+ +P ENL++PD 
Sbjct  325  ELPEGELPQPGASVAGPPPPRAWADRDPEAAARLSAARAGVNTLAERLHLPQENLITPDT  384

Query  378  VRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            VRR+CWE      +SPDP A  EA LR   AR WQ+E V P+LT AL
Sbjct  385  VRRVCWE----PPASPDPDAVAEA-LREHGARRWQIEHVTPVLTRAL  426


>gi|284990407|ref|YP_003408961.1| 3'-5' exonuclease [Geodermatophilus obscurus DSM 43160]
 gi|284063652|gb|ADB74590.1| 3'-5' exonuclease [Geodermatophilus obscurus DSM 43160]
Length=418

 Score =  372 bits (956),  Expect = 5e-101, Method: Compositional matrix adjust.
 Identities = 216/415 (53%), Positives = 263/415 (64%), Gaps = 16/415 (3%)

Query  12   ESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAY  71
            + E T     PLL P  G+P +  T   +   AE L  G GP AVDAERASG+RY  RAY
Sbjct  15   DDEPTAPPAVPLLAPRDGLPPVIETSTALVEYAEALAAGSGPVAVDAERASGYRYGQRAY  74

Query  72   LIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPA  131
            L+Q+RR   GT LIDP+     PL  L+ V   +   EW+LH+A QDLP LAEVG+ P  
Sbjct  75   LVQLRRVGTGTGLIDPI-----PLPDLSVVQSAIVDAEWVLHAASQDLPSLAEVGLVPAR  129

Query  132  LYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLI  191
            L+DTELA RLAG  RV L A+VE LLG  L KGH AADWS RPLP  WL YAALDVE+L+
Sbjct  130  LFDTELAARLAGLPRVGLGAVVESLLGYRLEKGHSAADWSTRPLPEEWLVYAALDVEVLV  189

Query  192  ELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAA  251
            +LR A++ VL EQGKT+WA QEF  +    + PP  A R D WRRTSG+H +  RR L  
Sbjct  190  DLRDALAAVLEEQGKTEWARQEFAAI--LAAGPP--APRADPWRRTSGVHGLRSRRQLGM  245

Query  252  VRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVW  311
            +R LW ARD +A+RRDIAP R+LPD+A++ A  ADP++   L+ LPVF GR  R+    W
Sbjct  246  LRSLWQARDELARRRDIAPGRVLPDAAMVSAVQADPRTEAALLELPVFRGRANRKLVGTW  305

Query  312  WAALAAARESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPT  369
            + AL   RE P+   P  + P +GPPP  RW  R PAAA RL AARA L E++    +P 
Sbjct  306  FGALTRGRELPESELPLHSRPGDGPPPVNRWADRDPAAATRLQAARAGLAELAATHSLPV  365

Query  370  ENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            ENL+SPDLVRRL W     +   P     V A LR G AR WQ+EL   +LT AL
Sbjct  366  ENLLSPDLVRRLMW-----TPPEPRDAETVAATLRAGGAREWQVELTRDLLTDAL  415


>gi|302525782|ref|ZP_07278124.1| ribonuclease D [Streptomyces sp. AA4]
 gi|302434677|gb|EFL06493.1| ribonuclease D [Streptomyces sp. AA4]
Length=420

 Score =  372 bits (956),  Expect = 6e-101, Method: Compositional matrix adjust.
 Identities = 221/416 (54%), Positives = 280/416 (68%), Gaps = 19/416 (4%)

Query  14   EGTESEPTPLL--RPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAY  71
            E TE   TP+L   PA G P +      +A A   L  G G  AVD ERASG+RY  +AY
Sbjct  14   ETTEDSGTPVLLREPAEGTPPVVADPDALAEACARLAAGTGAVAVDTERASGYRYWPKAY  73

Query  72   LIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPA  131
            L+Q+RR  +GTVLIDP++   D    LAP+ +VL+  EW+LH+A QDLPCLAE+ +RP +
Sbjct  74   LVQLRREGSGTVLIDPIALADD----LAPLRDVLNDTEWVLHAASQDLPCLAELNLRPRS  129

Query  132  LYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLI  191
            L+DTELAGRLAG++RV L  +VE LLG  L KGH AADWSKRPLP  WLNYAALDVELL 
Sbjct  130  LFDTELAGRLAGYERVALGTLVELLLGYTLEKGHSAADWSKRPLPVDWLNYAALDVELLN  189

Query  192  ELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAA  251
            ELR  +   L  QGK +WA QEFE +R+        A R + WRRTSG+HK+   RGLAA
Sbjct  190  ELREKLEAELTAQGKLEWARQEFEAVRTAPP----PAPRAEPWRRTSGVHKIRSPRGLAA  245

Query  252  VRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVW  311
            VRE+W ARD +A++RD AP RILPDSAI++A  +DPK+V++L ALPVF GR QR+  A W
Sbjct  246  VREMWQARDELARKRDRAPSRILPDSAIVNAVTSDPKTVEELQALPVFSGRVQRKYTASW  305

Query  312  WAALAAARESP--DPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPT  369
               L AA+  P  + P  ++P++GPPP  RW  + P AAARL AARAAL  +++  ++P 
Sbjct  306  LRHLQAAKALPASELPSPSQPSDGPPPVNRWADKDPDAAARLAAARAALAAIAEDRKLPV  365

Query  370  ENLVSPDLVRRLCWE-WEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            ENL+ PDLVRR CW    D+S+ S      V   L+ G AR WQ+EL   +L+ AL
Sbjct  366  ENLLLPDLVRRTCWRPPADLSEDS------VAEALKAGGARPWQIELTAAVLSKAL  415


>gi|256375684|ref|YP_003099344.1| 3'-5' exonuclease [Actinosynnema mirum DSM 43827]
 gi|255919987|gb|ACU35498.1| 3'-5' exonuclease [Actinosynnema mirum DSM 43827]
Length=414

 Score =  371 bits (952),  Expect = 2e-100, Method: Compositional matrix adjust.
 Identities = 220/418 (53%), Positives = 275/418 (66%), Gaps = 15/418 (3%)

Query  13   SEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYL  72
            ++ T ++P PL  PA G+P +      +  AA+ L    GP AVD ERASG+RYS RAYL
Sbjct  9    TDPTGAQPVPLTEPADGVPPVVADSSALRRAADALAGAEGPVAVDTERASGYRYSQRAYL  68

Query  73   IQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPAL  132
            +Q+RR  AGTVL+DP++ GG     L P+ E L   EW+LH+A QDLPCLAE+G+ P AL
Sbjct  69   VQLRREGAGTVLVDPIALGGR----LDPLVEALEGTEWVLHAASQDLPCLAELGLTPSAL  124

Query  133  YDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIE  192
            +DTELAGRLAGF+RV L  +VE LLG  L KGHGAADWS+RPLP+ WLNYAALDVELL++
Sbjct  125  FDTELAGRLAGFERVALGTLVELLLGYRLEKGHGAADWSRRPLPADWLNYAALDVELLVQ  184

Query  193  LRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAV  252
            LR  +   L +QGK +WA +EF+  R+     P    R + WRRTSGIH++   R LAAV
Sbjct  185  LRDVLEEELRQQGKLEWALEEFDAARTA----PLPKPRAEPWRRTSGIHRIRSTRQLAAV  240

Query  253  RELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWW  312
            R LW  RD +A+ RD+AP R+LPDSA++DAA  +P     L+ALPVF GR QRR A  W 
Sbjct  241  RSLWETRDALARERDLAPGRVLPDSALVDAATRNPADEAALLALPVFRGRAQRRMAGTWM  300

Query  313  AAL--AAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTE  370
             AL  AAA    + PE A+  +GPPP  RW  + PAAAARL AAR AL EV++   +P E
Sbjct  301  GALRKAAALPRAELPETAQHHDGPPPANRWADKDPAAAARLAAARTALAEVAEANTLPVE  360

Query  371  NLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAP  428
            NL+ PDLVRR CW+       S   +  V A LR G AR WQ+ L    L+ AL   P
Sbjct  361  NLLLPDLVRRTCWQ-----PPSDTSLDGVTAALREGGAREWQIGLTARALSEALAATP  413


>gi|300784546|ref|YP_003764837.1| ribonuclease D [Amycolatopsis mediterranei U32]
 gi|299794060|gb|ADJ44435.1| ribonuclease D [Amycolatopsis mediterranei U32]
 gi|340525969|gb|AEK41174.1| ribonuclease D [Amycolatopsis mediterranei S699]
Length=407

 Score =  370 bits (950),  Expect = 3e-100, Method: Compositional matrix adjust.
 Identities = 225/407 (56%), Positives = 278/407 (69%), Gaps = 15/407 (3%)

Query  20   PTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAE  79
            P  L  PA G P +     E+A A   L  G G  AVD ERASG+RY  +AYL+Q+RR  
Sbjct  9    PVLLREPAEGTPPVITDAAELAEACAKLAAGTGAVAVDTERASGYRYFPKAYLVQLRREG  68

Query  80   AGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAG  139
            AGTVLIDP++  G+    LAP+ EVL++ EW+LH+A QDLPCLAE+G+ P AL+DTELAG
Sbjct  69   AGTVLIDPIALDGE----LAPLREVLNSLEWVLHAASQDLPCLAELGLHPAALFDTELAG  124

Query  140  RLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISR  199
            RLAG++RV L  +VE LLG  L KGH AADWSKRPLP  WLNYAALDVELLI+LR  +  
Sbjct  125  RLAGYERVALGTLVELLLGYTLEKGHSAADWSKRPLPVDWLNYAALDVELLIQLREKLEA  184

Query  200  VLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTAR  259
             L  QGK +WA QEFE    F    PP   R + WRRTSG+HK+   RGLAAVRELW AR
Sbjct  185  ELGAQGKLEWARQEFE----FVRTAPPPPPRAEPWRRTSGVHKIRSPRGLAAVRELWQAR  240

Query  260  DRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAAR  319
            D +A++RD AP RILPDSAI++A  ADPK+V++L ALPVF GR QR+  A W   L AA+
Sbjct  241  DELARKRDRAPSRILPDSAIVNAVTADPKTVEELQALPVFSGRVQRKYTASWLRHLQAAK  300

Query  320  ESP--DPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDL  377
              P  + P  ++P +GPPP  RW  + P AAARL AARAALT +++  R+P ENL+ PDL
Sbjct  301  ALPASELPSPSQPTDGPPPVNRWADKDPDAAARLSAARAALTAIAEDRRLPVENLLLPDL  360

Query  378  VRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            VRR C  W   +++  D +A V   LR   AR WQ+EL   +L+ AL
Sbjct  361  VRRTC--WRPPAETDEDSVAEV---LRASGARPWQVELTAAVLSKAL  402


>gi|302522528|ref|ZP_07274870.1| ribonuclease D [Streptomyces sp. SPB78]
 gi|302431423|gb|EFL03239.1| ribonuclease D [Streptomyces sp. SPB78]
Length=431

 Score =  370 bits (949),  Expect = 3e-100, Method: Compositional matrix adjust.
 Identities = 221/407 (55%), Positives = 272/407 (67%), Gaps = 16/407 (3%)

Query  20   PTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAE  79
            P PLL P  GIP +      +AAA      G GP AVDAERASG+RY  RAYL+Q+RRA 
Sbjct  34   PVPLLEPREGIPPVIADPESLAAAVAAFASGSGPVAVDAERASGYRYGQRAYLVQLRRAG  93

Query  80   AGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAG  139
            AGT LIDPV+        L+ +   L+  EW LH+A QDLPCL E+GM P +L+DTELAG
Sbjct  94   AGTALIDPVA-----CPDLSGLGAALANAEWDLHAATQDLPCLREIGMVPHSLFDTELAG  148

Query  140  RLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISR  199
            RLAGF RV L AMVE +LG  L KGH A DWS RPLP  WL YAALDVELL++LR A+ +
Sbjct  149  RLAGFPRVGLGAMVENVLGYTLEKGHSAVDWSTRPLPEPWLRYAALDVELLVDLRDALEK  208

Query  200  VLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTAR  259
             L  QGK +WA +EF+ + S        A R+D WRRTSG+H+V  RR LA VRELWT R
Sbjct  209  ELERQGKLEWALEEFDAIASAPP----PAPRKDPWRRTSGMHRVRRRRQLAVVRELWTLR  264

Query  260  DRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAAR  319
            DRIA+RRD++P ++LPD+AI++AA+A P +V  L ALP FG R Q+R    W AA+  AR
Sbjct  265  DRIARRRDVSPGKVLPDAAIVEAALAVPVNVHALGALPAFGQRAQKRQLDQWQAAIDRAR  324

Query  320  ESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDL  377
            E P+   P+      GPPPP  W  R P AAARL AARA +  +++R+ +P ENL++PD 
Sbjct  325  ELPEGELPQPGASVAGPPPPRAWADRDPEAAARLSAARAGVNTLAERLHLPQENLITPDT  384

Query  378  VRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            VRR+CWE      +SPDP A  EA LR   AR WQ+E V P+LT AL
Sbjct  385  VRRVCWE----PPASPDPDAVAEA-LRGYGARHWQIEHVTPVLTRAL  426


>gi|318061059|ref|ZP_07979780.1| ribonuclease D [Streptomyces sp. SA3_actG]
 gi|318079172|ref|ZP_07986504.1| ribonuclease D [Streptomyces sp. SA3_actF]
Length=431

 Score =  369 bits (947),  Expect = 5e-100, Method: Compositional matrix adjust.
 Identities = 221/407 (55%), Positives = 272/407 (67%), Gaps = 16/407 (3%)

Query  20   PTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYLIQIRRAE  79
            P PLL P  GIP +      +AAA      G GP AVDAERASG+RY  RAYL+Q+RRA 
Sbjct  34   PVPLLEPREGIPPVIADPESLAAAVAAFASGSGPVAVDAERASGYRYGQRAYLVQLRRAG  93

Query  80   AGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPALYDTELAG  139
            AGT LIDPV+        L+ +   L+  EW LH+A QDLPCL E+GM P +L+DTELAG
Sbjct  94   AGTALIDPVA-----CPDLSGLGAALANAEWDLHAATQDLPCLREIGMVPHSLFDTELAG  148

Query  140  RLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIELRAAISR  199
            RLAGF RV L AMVE +LG  L KGH A DWS RPLP  WL YAALDVELL++LR A+ +
Sbjct  149  RLAGFPRVGLGAMVENVLGYTLEKGHSAVDWSTRPLPEPWLRYAALDVELLVDLRDALEK  208

Query  200  VLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAVRELWTAR  259
             L  QGK +WA +EF+ + S        A R+D WRRTSG+H+V  RR LA VRELWT R
Sbjct  209  ELERQGKLEWALEEFDAIASAPP----PAPRKDPWRRTSGMHRVRRRRQLAVVRELWTLR  264

Query  260  DRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWWAALAAAR  319
            DRIA+RRD++P ++LPD+AI++AA+A P +V  L ALP FG R Q+R    W AA+  AR
Sbjct  265  DRIARRRDVSPGKVLPDAAIVEAALAVPVNVHALGALPAFGQRAQKRQLDQWQAAIDRAR  324

Query  320  ESPDP--PEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTENLVSPDL  377
            E P+   P+      GPPPP  W  R P AAARL AARA +  +++R+ +P ENL++PD 
Sbjct  325  ELPEGELPQPGASVAGPPPPRAWADRDPEAAARLSAARAGVNTLAERLHLPQENLITPDT  384

Query  378  VRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAAL  424
            VRR+CWE      +SPDP A  EA LR   AR WQ+E V P+LT AL
Sbjct  385  VRRVCWE----PPASPDPDAVAEA-LRGYGARRWQIEHVTPVLTRAL  426


>gi|291436577|ref|ZP_06575967.1| ribonuclease D [Streptomyces ghanaensis ATCC 14672]
 gi|291339472|gb|EFE66428.1| ribonuclease D [Streptomyces ghanaensis ATCC 14672]
Length=432

 Score =  365 bits (938),  Expect = 6e-99, Method: Compositional matrix adjust.
 Identities = 218/422 (52%), Positives = 267/422 (64%), Gaps = 17/422 (4%)

Query  13   SEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGFRYSGRAYL  72
            S  TE+ P PLL P  GIP +      +A        G GP AVDAERASG+RY  RAYL
Sbjct  26   SSATEA-PIPLLEPHEGIPPVIADEAALAEVIAAFAAGTGPVAVDAERASGYRYGQRAYL  84

Query  73   IQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAEVGMRPPAL  132
            +Q+RR  AGT LIDPV+        L+ + E LS  EW+LH+A QDLPCL E+GM P  L
Sbjct  85   VQLRRQGAGTALIDPVA-----CPDLSALGEALSGVEWVLHAATQDLPCLREIGMLPTRL  139

Query  133  YDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAALDVELLIE  192
            +DTELAGRLAGF RV L AMVE +LG  L KGH A DWS RPLP  WL YAALDVELL++
Sbjct  140  FDTELAGRLAGFPRVGLGAMVENVLGYVLEKGHSAVDWSTRPLPEPWLRYAALDVELLVD  199

Query  193  LRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVHDRRGLAAV  252
            LR A+ + L  QGK +WA QEF+ + S     PP   R+D WRRTSG+HKV  RR +A V
Sbjct  200  LRNALEKELDRQGKLEWARQEFDAIASA----PPPEPRKDPWRRTSGMHKVRRRRQMAVV  255

Query  253  RELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQRRSAAVWW  312
            RELW  RDRIA+RRD++P ++LPD+AI++AA+A P     L AL  FG R  RR    W 
Sbjct  256  RELWQTRDRIARRRDLSPGKVLPDAAIVEAALALPADARALAALNGFGQRAGRRQLEQWQ  315

Query  313  AAL--AAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVSQRVRVPTE  370
            AA+  A A      P+  +P  GPPPP  W  + P AAARL AARA +  +++R+ +P E
Sbjct  316  AAVDRAKALSESQLPQPGQPVTGPPPPRAWADKDPVAAARLSAARAGVAALAERLNMPPE  375

Query  371  NLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTAALTGAPDA  430
            NL++PD VRR+CWE        P    +V A L    ARAWQ+E V P+L  AL    D 
Sbjct  376  NLIAPDTVRRVCWE-----PPQPADARSVAAVLTEYGARAWQVEQVTPVLVTALASGADQ  430

Query  431  GA  432
            GA
Sbjct  431  GA  432


>gi|302866117|ref|YP_003834754.1| 3'-5' exonuclease [Micromonospora aurantiaca ATCC 27029]
 gi|315502675|ref|YP_004081562.1| 3'-5' exonuclease [Micromonospora sp. L5]
 gi|302568976|gb|ADL45178.1| 3'-5' exonuclease [Micromonospora aurantiaca ATCC 27029]
 gi|315409294|gb|ADU07411.1| 3'-5' exonuclease [Micromonospora sp. L5]
Length=439

 Score =  365 bits (937),  Expect = 8e-99, Method: Compositional matrix adjust.
 Identities = 216/425 (51%), Positives = 264/425 (63%), Gaps = 19/425 (4%)

Query  2    CPEPSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERA  61
             PEP+ AG   SE       PL  P  G P    T  E+         G GP A+DAERA
Sbjct  27   LPEPADAG---SETDTGAAVPLTAPRDGTPAPVATPAELDEVVARFAAGTGPVALDAERA  83

Query  62   SGFRYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPC  121
            SG+RYS RAYL+Q+RR  AGT LIDP+     PL  L+ +  V++  EW+LH+A QDL C
Sbjct  84   SGYRYSQRAYLVQLRRGGAGTALIDPL-----PLPDLSALDAVIAETEWVLHAASQDLAC  138

Query  122  LAEVGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLN  181
            LAEVG+RP  L+DTELA RLAGF+RV LAA+ E+LLG  L K H AADWS RPLP +WL 
Sbjct  139  LAEVGLRPRRLFDTELAARLAGFERVGLAALTEQLLGFSLEKHHSAADWSSRPLPESWLT  198

Query  182  YAALDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIH  241
            YAALDVELL++LR ++   L  QGK+ WAA+EF+ L    + P     R + WRRTSGIH
Sbjct  199  YAALDVELLVDLRDSLDEELQRQGKSGWAAEEFDALVRNGASP---RVRAEPWRRTSGIH  255

Query  242  KVHDRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGG  301
            +V   R  A VR LW ARD+IA RRD AP R+LPDSAI+ AA  DPK    L+ LP FGG
Sbjct  256  RVRGARAQARVRSLWYARDQIASRRDAAPGRVLPDSAIVAAAELDPKDEKTLLTLPGFGG  315

Query  302  RNQRRSAAVWWAALAAARESPDPPEIAEPA-NGPPPPGRWVRRKPAAAARLDAARAALTE  360
            R+ RR A  W AAL  AR+ PD      PA  GPPPP RW  R P AA RL  AR  +  
Sbjct  316  RSVRRLARTWLAALDDARQLPDDALPVSPAVEGPPPPHRWAERDPVAAGRLARAREVVVG  375

Query  361  VSQRVRVPTENLVSPDLVRRLCWE-WEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPI  419
             +   R+P ENL++PD +RRL W+   +I+  +      V   LR   AR WQ+ L++P 
Sbjct  376  TAGAHRLPAENLIAPDSIRRLAWQPPAEITDET------VAETLRGFGAREWQIGLLLPA  429

Query  420  LTAAL  424
            LT AL
Sbjct  430  LTEAL  434


>gi|302557678|ref|ZP_07310020.1| ribonuclease D [Streptomyces griseoflavus Tu4000]
 gi|302475296|gb|EFL38389.1| ribonuclease D [Streptomyces griseoflavus Tu4000]
Length=430

 Score =  364 bits (935),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 220/429 (52%), Positives = 275/429 (65%), Gaps = 22/429 (5%)

Query  5    PSHAGAAESEGTESEPTPLLRPAGGIPDLCVTVGEIAAAAELLDRGRGPFAVDAERASGF  64
            P   G++ +E     PTPLL P  GIP +      +A A      G GP AVDAERASG+
Sbjct  21   PDDGGSSVTEA----PTPLLEPREGIPPVIADEAALAEAVAAFAAGSGPVAVDAERASGY  76

Query  65   RYSGRAYLIQIRRAEAGTVLIDPVSHGGDPLTVLAPVAEVLSTNEWILHSADQDLPCLAE  124
            RY  RAYL+Q+RR  AGT LIDPV+        L+ + E LS  EW+LH+A QDLPCL E
Sbjct  77   RYGQRAYLVQLRREGAGTALIDPVA-----CPDLSSLGEALSGVEWVLHAATQDLPCLRE  131

Query  125  VGMRPPALYDTELAGRLAGFDRVNLAAMVERLLGLGLTKGHGAADWSKRPLPSAWLNYAA  184
            +GM P  L+DTELAGRLAGF RV L AMVE +LG  L KGH A DWS RPLP  WL YAA
Sbjct  132  IGMVPSRLFDTELAGRLAGFPRVGLGAMVENVLGFVLEKGHSAVDWSTRPLPEPWLRYAA  191

Query  185  LDVELLIELRAAISRVLAEQGKTDWAAQEFEHLRSFESRPPPAAARQDRWRRTSGIHKVH  244
            LDVELL++LR A+ + L  QGK DWA QEF+ + S     PP   R+D WRRTSG+HKV 
Sbjct  192  LDVELLVDLRDALEKELDRQGKLDWARQEFDAIASA----PPPEPRKDPWRRTSGMHKVR  247

Query  245  DRRGLAAVRELWTARDRIAQRRDIAPRRILPDSAIIDAAIADPKSVDDLVALPVFGGRNQ  304
             RR +A VRELW  RDRIA+RRD++P ++L D+AI++AA+A P ++  + AL  FG R  
Sbjct  248  RRRQMAVVRELWETRDRIARRRDVSPGKVLSDAAIVEAALALPANLHAMAALNGFGQRVG  307

Query  305  RRSAAVWWAAL--AAARESPDPPEIAEPANGPPPPGRWVRRKPAAAARLDAARAALTEVS  362
            RR    W AA+  A A      P+  +P  GPPPP  W  + P AAARL AARA + E++
Sbjct  308  RRQLEQWQAAVDRAKALSEAQLPQPGQPVTGPPPPRAWADKDPVAAARLSAARAGVAELA  367

Query  363  QRVRVPTENLVSPDLVRRLCWEWEDISQSSPDPIAAVEAYLRTGQARAWQLELVVPILTA  422
            +R+ +P ENL++PD VRR+CWE     + S      V A L    ARAWQ++ V P+L A
Sbjct  368  ERLNMPPENLITPDTVRRVCWEPPGPDERS------VAAALTAHGARAWQVDQVTPVLVA  421

Query  423  AL-TGAPDA  430
            AL T +P A
Sbjct  422  ALATSSPPA  430



Lambda     K      H
   0.318    0.134    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 897400889630


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40