BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2707

Length=324
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609844|ref|NP_217223.1|  hypothetical protein Rv2707 [Mycoba...   644    0.0   
gi|183982020|ref|YP_001850311.1|  hypothetical protein MMAR_2006 ...   479    4e-133
gi|118618670|ref|YP_907002.1|  hypothetical protein MUL_3347 [Myc...   478    6e-133
gi|296171840|ref|ZP_06852939.1|  ribonuclease BN [Mycobacterium p...   469    3e-130
gi|240169691|ref|ZP_04748350.1|  hypothetical protein MkanA1_1028...   463    1e-128
gi|15827490|ref|NP_301753.1|  integral membrane protein [Mycobact...   463    1e-128
gi|118462877|ref|YP_882777.1|  hypothetical protein MAV_3600 [Myc...   445    5e-123
gi|41408921|ref|NP_961757.1|  hypothetical protein MAP2823 [Mycob...   444    6e-123
gi|342858425|ref|ZP_08715080.1|  hypothetical protein MCOL_06106 ...   444    8e-123
gi|254821654|ref|ZP_05226655.1|  hypothetical protein MintA_17092...   437    1e-120
gi|108799147|ref|YP_639344.1|  ribonuclease BN [Mycobacterium sp....   393    2e-107
gi|118471083|ref|YP_887086.1|  hypothetical protein MSMEG_2755 [M...   392    3e-107
gi|333991089|ref|YP_004523703.1|  hypothetical protein JDM601_245...   392    4e-107
gi|120403444|ref|YP_953273.1|  ribonuclease BN [Mycobacterium van...   381    8e-104
gi|145224526|ref|YP_001135204.1|  ribonuclease BN [Mycobacterium ...   376    3e-102
gi|169630108|ref|YP_001703757.1|  ribonuclease BN [Mycobacterium ...   363    1e-98 
gi|289444249|ref|ZP_06433993.1|  conserved hypothetical protein [...   338    7e-91 
gi|317506481|ref|ZP_07964282.1|  ribonuclease BN family protein [...   276    4e-72 
gi|333919429|ref|YP_004493010.1|  hypothetical protein AS9A_1761 ...   276    4e-72 
gi|296393380|ref|YP_003658264.1|  ribonuclease BN [Segniliparus r...   270    2e-70 
gi|229491263|ref|ZP_04385089.1|  ribonuclease BN [Rhodococcus ery...   259    5e-67 
gi|226306295|ref|YP_002766255.1|  hypothetical protein RER_28080 ...   258    7e-67 
gi|300784486|ref|YP_003764777.1|  ribonuclease BN [Amycolatopsis ...   253    2e-65 
gi|302525720|ref|ZP_07278062.1|  ribonuclease BN [Streptomyces sp...   251    9e-65 
gi|111023775|ref|YP_706747.1|  hypothetical protein RHA1_ro06817 ...   250    2e-64 
gi|226366211|ref|YP_002783994.1|  hypothetical protein ROP_68020 ...   248    7e-64 
gi|312139428|ref|YP_004006764.1|  ribonuclease bn [Rhodococcus eq...   248    8e-64 
gi|296139552|ref|YP_003646795.1|  ribonuclease BN [Tsukamurella p...   240    2e-61 
gi|256375638|ref|YP_003099298.1|  ribonuclease BN [Actinosynnema ...   236    3e-60 
gi|54025740|ref|YP_119982.1|  hypothetical protein nfa37700 [Noca...   234    2e-59 
gi|257056430|ref|YP_003134262.1|  hypothetical protein Svir_24410...   232    7e-59 
gi|134098374|ref|YP_001104035.1|  ribonuclease BN [Saccharopolysp...   231    9e-59 
gi|326384456|ref|ZP_08206136.1|  ribonuclease BN [Gordonia neofel...   223    4e-56 
gi|262202174|ref|YP_003273382.1|  ribonuclease BN [Gordonia bronc...   221    1e-55 
gi|284989615|ref|YP_003408169.1|  ribonuclease BN [Geodermatophil...   219    5e-55 
gi|331696938|ref|YP_004333177.1|  ribonuclease BN [Pseudonocardia...   218    1e-54 
gi|284991960|ref|YP_003410514.1|  ribonuclease BN [Geodermatophil...   198    1e-48 
gi|258653906|ref|YP_003203062.1|  ribonuclease BN [Nakamurella mu...   191    2e-46 
gi|258650769|ref|YP_003199925.1|  ribonuclease BN [Nakamurella mu...   187    2e-45 
gi|158313101|ref|YP_001505609.1|  ribonuclease BN [Frankia sp. EA...   177    3e-42 
gi|288920775|ref|ZP_06415075.1|  ribonuclease BN [Frankia sp. EUN...   160    3e-37 
gi|86742177|ref|YP_482577.1|  ribonuclease BN [Frankia sp. CcI3] ...   159    8e-37 
gi|111225044|ref|YP_715838.1|  hypothetical protein FRAAL5685 [Fr...   157    3e-36 
gi|302541789|ref|ZP_07294131.1|  putative integral membrane prote...   153    4e-35 
gi|320007739|gb|ADW02589.1|  ribonuclease BN [Streptomyces flavog...   153    5e-35 
gi|297191204|ref|ZP_06908602.1|  integral membrane protein [Strep...   152    8e-35 
gi|345002845|ref|YP_004805699.1|  ribonuclease BN [Streptomyces s...   152    1e-34 
gi|312195054|ref|YP_004015115.1|  ribonuclease BN [Frankia sp. Eu...   150    2e-34 
gi|328885970|emb|CCA59209.1|  putative integral membrane protein ...   149    4e-34 
gi|84496269|ref|ZP_00995123.1|  putative integral membrane protei...   149    5e-34 


>gi|15609844|ref|NP_217223.1| hypothetical protein Rv2707 [Mycobacterium tuberculosis H37Rv]
 gi|15842245|ref|NP_337282.1| hypothetical protein MT2780 [Mycobacterium tuberculosis CDC1551]
 gi|31793879|ref|NP_856372.1| hypothetical protein Mb2726 [Mycobacterium bovis AF2122/97]
 78 more sequence titles
 Length=324

 Score =  644 bits (1660),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 324/324 (100%), Positives = 324/324 (100%), Gaps = 0/324 (0%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP
Sbjct  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS
Sbjct  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES
Sbjct  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
            LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL
Sbjct  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
            AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA
Sbjct  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300

Query  301  RIGVGTTTYSSTAQHSAVAAEPPS  324
            RIGVGTTTYSSTAQHSAVAAEPPS
Sbjct  301  RIGVGTTTYSSTAQHSAVAAEPPS  324


>gi|183982020|ref|YP_001850311.1| hypothetical protein MMAR_2006 [Mycobacterium marinum M]
 gi|183175346|gb|ACC40456.1| conserved membrane protein [Mycobacterium marinum M]
Length=324

 Score =  479 bits (1232),  Expect = 4e-133, Method: Compositional matrix adjust.
 Identities = 260/324 (81%), Positives = 290/324 (90%), Gaps = 0/324 (0%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MSDQVP+P RHHIWRI+ RTLSKSWDDSIFSESAQA FWSALSLPPLLLGMLGSLAYVAP
Sbjct  1    MSDQVPRPSRHHIWRISLRTLSKSWDDSIFSESAQAGFWSALSLPPLLLGMLGSLAYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFG DTLPAIEK+ +S  H FFSPSVV+EIIEPTI DIT NARGEV S+GFLISLWAGSS
Sbjct  61   LFGQDTLPAIEKTIISMTHRFFSPSVVDEIIEPTIRDITANARGEVVSVGFLISLWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AIS++VDA+VEAHDQTPLRHPVRQRFFALFLYVV L+F+V +APV V+GPRKVSEHIP++
Sbjct  121  AISSYVDAIVEAHDQTPLRHPVRQRFFALFLYVVGLLFIVISAPVAVMGPRKVSEHIPDN  180

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
            ++NL+ YGYYPALI  LTVGVI+LYRV+LPVPLPTHRL+LGAVLA+AVFLIATLGLR YL
Sbjct  181  MSNLMHYGYYPALIAVLTVGVIILYRVSLPVPLPTHRLILGAVLAMAVFLIATLGLRFYL  240

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
             WIT TGYTYGAL+TPIAFLLFAFFGGFA+M+GAELNAA+QEEWPAPATHAHRL NWL+A
Sbjct  241  GWITHTGYTYGALSTPIAFLLFAFFGGFAVMIGAELNAAIQEEWPAPATHAHRLRNWLRA  300

Query  301  RIGVGTTTYSSTAQHSAVAAEPPS  324
            R    T +  S +  S  A +PPS
Sbjct  301  RTAAATGSADSESPQSNTAVDPPS  324


>gi|118618670|ref|YP_907002.1| hypothetical protein MUL_3347 [Mycobacterium ulcerans Agy99]
 gi|118570780|gb|ABL05531.1| conserved membrane protein [Mycobacterium ulcerans Agy99]
Length=324

 Score =  478 bits (1230),  Expect = 6e-133, Method: Compositional matrix adjust.
 Identities = 260/324 (81%), Positives = 290/324 (90%), Gaps = 0/324 (0%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MS+QVP+P RHHIWRI+ RTLSKSWDDSIFSESAQA FWSALSLPPLLLGMLGSLAYVAP
Sbjct  1    MSEQVPRPSRHHIWRISLRTLSKSWDDSIFSESAQAGFWSALSLPPLLLGMLGSLAYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFG DTLPAIEK+ +S  H FFSPSVV+EIIEPTI DIT NARGEV S+GFLISLWAGSS
Sbjct  61   LFGQDTLPAIEKTIISMTHRFFSPSVVDEIIEPTIRDITANARGEVVSVGFLISLWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AIS++VDA+VEAHDQTPLRHPVRQRFFALFLYVV L+F+V +APV V+GPRKVSEHIP+S
Sbjct  121  AISSYVDAIVEAHDQTPLRHPVRQRFFALFLYVVGLLFIVISAPVAVMGPRKVSEHIPDS  180

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
            ++NL+ YGYYPALI  LTVGVI+LYRV+LPVPLPTHRL+LGAVLA+AVFLIATLGLR YL
Sbjct  181  MSNLMHYGYYPALIAVLTVGVIILYRVSLPVPLPTHRLILGAVLAMAVFLIATLGLRFYL  240

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
             WIT TGYTYGAL+TPIAFLLFAFFGGFA+M+GAELNAA+QEEWPAPATHAHRL NWL+A
Sbjct  241  GWITHTGYTYGALSTPIAFLLFAFFGGFAVMIGAELNAAIQEEWPAPATHAHRLRNWLRA  300

Query  301  RIGVGTTTYSSTAQHSAVAAEPPS  324
            R    T +  S +  S  A +PPS
Sbjct  301  RTAAATGSADSESPQSNTAVDPPS  324


>gi|296171840|ref|ZP_06852939.1| ribonuclease BN [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295893924|gb|EFG73693.1| ribonuclease BN [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=330

 Score =  469 bits (1206),  Expect = 3e-130, Method: Compositional matrix adjust.
 Identities = 264/326 (81%), Positives = 283/326 (87%), Gaps = 4/326 (1%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MSDQV KP RHHIWR++ RTL+KSWDDSIFSESAQA FWSALSLPPLLLGMLGSLAYVAP
Sbjct  1    MSDQVAKPSRHHIWRLSVRTLAKSWDDSIFSESAQAGFWSALSLPPLLLGMLGSLAYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFGPDTL AIEKS +S   SFFSPSVVNEIIEPTI D+T NARGEV S+GFLIS+WAGSS
Sbjct  61   LFGPDTLTAIEKSIISAIRSFFSPSVVNEIIEPTIRDVTANARGEVVSVGFLISMWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AISA+VDAVVEAHDQTPLRHPVRQR FALFLYVVMLVF+V  APV+VVGPRKVSEHIP  
Sbjct  121  AISAYVDAVVEAHDQTPLRHPVRQRLFALFLYVVMLVFVVCAAPVLVVGPRKVSEHIPYD  180

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
            LAN+LRYGYYPALILGL VGV++LYRVALP PLPTHRL+ GAVLA AVFLIATLGLRVYL
Sbjct  181  LANVLRYGYYPALILGLLVGVVILYRVALPEPLPTHRLLFGAVLATAVFLIATLGLRVYL  240

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
             WIT TGYTYGALATPIAFLLFAFFGGFA+MLGAE NAA+QEE+PAP THAHRL  WL+A
Sbjct  241  GWITSTGYTYGALATPIAFLLFAFFGGFAVMLGAEFNAAIQEEFPAPKTHAHRLRKWLQA  300

Query  301  RIGVGTTT----YSSTAQHSAVAAEP  322
            RI V   T           +AV AEP
Sbjct  301  RITVPKRTAGAPPEPAPADNAVTAEP  326


>gi|240169691|ref|ZP_04748350.1| hypothetical protein MkanA1_10287 [Mycobacterium kansasii ATCC 
12478]
Length=314

 Score =  463 bits (1192),  Expect = 1e-128, Method: Compositional matrix adjust.
 Identities = 267/301 (89%), Positives = 282/301 (94%), Gaps = 0/301 (0%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MSDQ PKP RHHIWRI+ RTLSKSWDDSIFSESAQA FWSALSLPPLLLGMLGSLAYVAP
Sbjct  5    MSDQTPKPSRHHIWRISLRTLSKSWDDSIFSESAQAGFWSALSLPPLLLGMLGSLAYVAP  64

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFG DTLPAIEK+ +STAHSFFSPSVVNEIIEPTI DIT NARGEV SLGFLISLWAGSS
Sbjct  65   LFGQDTLPAIEKTIISTAHSFFSPSVVNEIIEPTIRDITANARGEVVSLGFLISLWAGSS  124

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AIS++VDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVF+VATAPV VVGPRKVSE IP S
Sbjct  125  AISSYVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFVVATAPVAVVGPRKVSERIPAS  184

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
            LAN+L YGYYPALI+GLT+GVI+LYRVALPVPLPTHRLV+GAVLA AVFLIATLGLR YL
Sbjct  185  LANILHYGYYPALIVGLTLGVIILYRVALPVPLPTHRLVIGAVLATAVFLIATLGLRFYL  244

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
             WIT TGYTYGAL+TPIAFLLFAFFGGFAIM+GAELNAA+QEEWPAPATHAHRL  WL+A
Sbjct  245  TWITSTGYTYGALSTPIAFLLFAFFGGFAIMIGAELNAAIQEEWPAPATHAHRLRTWLRA  304

Query  301  R  301
            R
Sbjct  305  R  305


>gi|15827490|ref|NP_301753.1| integral membrane protein [Mycobacterium leprae TN]
 gi|221229967|ref|YP_002503383.1| hypothetical protein MLBr_01017 [Mycobacterium leprae Br4923]
 gi|699178|gb|AAA62943.1| u1764d [Mycobacterium leprae]
 gi|13093040|emb|CAC31398.1| possible conserved integral membrane protein [Mycobacterium leprae]
 gi|219933074|emb|CAR71112.1| possible conserved integral membrane protein [Mycobacterium leprae 
Br4923]
Length=330

 Score =  463 bits (1192),  Expect = 1e-128, Method: Compositional matrix adjust.
 Identities = 245/325 (76%), Positives = 274/325 (85%), Gaps = 4/325 (1%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MS QV KP R HIWRI+ RTLSKSWDDSIFSESAQAAFWSALSLPPL+LGMLGSLAYVAP
Sbjct  1    MSGQVYKPTRQHIWRISLRTLSKSWDDSIFSESAQAAFWSALSLPPLVLGMLGSLAYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFG DTLP IE+  +S AHSFFSPSVVNEIIEPTI D+ N ARGEV SLGFLISLWAGSS
Sbjct  61   LFGEDTLPTIERRVISMAHSFFSPSVVNEIIEPTISDVNNGARGEVVSLGFLISLWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AISAFVDAVV+AHDQT LRHPV+QR FALFLY+ ML F+VATAP++VVGPRKV++ IP S
Sbjct  121  AISAFVDAVVKAHDQTLLRHPVKQRLFALFLYIAMLAFVVATAPLVVVGPRKVTKLIPHS  180

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
             AN+L  GYYPA+I+ L V V++LYRVALP+PLPTHRLV GA+LA AVF+I TLGLR+YL
Sbjct  181  WANMLHLGYYPAVIVSLLVAVMILYRVALPIPLPTHRLVFGAILATAVFVITTLGLRIYL  240

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
             WIT TGYTYGAL TPIAFLLFAFFGGFAIMLGAE NA++QE++PAP TH HRL NWL +
Sbjct  241  KWITGTGYTYGALTTPIAFLLFAFFGGFAIMLGAEFNASIQEKFPAPKTHTHRLHNWLTS  300

Query  301  RI----GVGTTTYSSTAQHSAVAAE  321
            R+    G  T T  +T   S  AAE
Sbjct  301  RLHTDPGRNTVTTQTTQHRSGRAAE  325


>gi|118462877|ref|YP_882777.1| hypothetical protein MAV_3600 [Mycobacterium avium 104]
 gi|118164164|gb|ABK65061.1| conserved hypothetical protein [Mycobacterium avium 104]
Length=333

 Score =  445 bits (1144),  Expect = 5e-123, Method: Compositional matrix adjust.
 Identities = 250/301 (84%), Positives = 273/301 (91%), Gaps = 0/301 (0%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MSDQV KP RHHIWRIT RTLSKSWDDSIFSESAQA FWSALSLPPLLLG+LG+LAYVAP
Sbjct  1    MSDQVAKPSRHHIWRITLRTLSKSWDDSIFSESAQAGFWSALSLPPLLLGLLGTLAYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFGPD LP+I +  +STAHS FSPSVVNEIIEPT+ DI NNARGEV SLGFLISLWAGSS
Sbjct  61   LFGPDMLPSILRQLISTAHSVFSPSVVNEIIEPTVRDIANNARGEVVSLGFLISLWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AISAFVD+VVEAHDQTPLRHPVRQRFFALFLYVVMLV +VATAP++VVGPRKV EHIP  
Sbjct  121  AISAFVDSVVEAHDQTPLRHPVRQRFFALFLYVVMLVGVVATAPLVVVGPRKVGEHIPLG  180

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
            L+N+LRYGYYPALI+GLT+ V++LYRVALP PLP+HRL+LGA+LA  VF+ ATLGLR YL
Sbjct  181  LSNVLRYGYYPALIVGLTIAVMILYRVALPEPLPSHRLILGAMLATTVFVTATLGLRFYL  240

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
             WIT TGYTYGAL+TPIAFLLFAFFGGFAIMLGAELNAAVQEE+PAP THAHRL  WL +
Sbjct  241  RWITSTGYTYGALSTPIAFLLFAFFGGFAIMLGAELNAAVQEEFPAPKTHAHRLRTWLFS  300

Query  301  R  301
            R
Sbjct  301  R  301


>gi|41408921|ref|NP_961757.1| hypothetical protein MAP2823 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|254776040|ref|ZP_05217556.1| hypothetical protein MaviaA2_15410 [Mycobacterium avium subsp. 
avium ATCC 25291]
 gi|41397280|gb|AAS05140.1| hypothetical protein MAP_2823 [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336458797|gb|EGO37754.1| putative membrane protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=333

 Score =  444 bits (1143),  Expect = 6e-123, Method: Compositional matrix adjust.
 Identities = 250/301 (84%), Positives = 273/301 (91%), Gaps = 0/301 (0%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MSDQV KP RHHIWRIT RTLSKSWDDSIFSESAQA FWSALSLPPLLLG+LG+LAYVAP
Sbjct  1    MSDQVAKPSRHHIWRITLRTLSKSWDDSIFSESAQAGFWSALSLPPLLLGLLGTLAYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFGPD LP+I +  +STAHS FSPSVVNEIIEPT+ DI NNARGEV SLGFLISLWAGSS
Sbjct  61   LFGPDMLPSILRQLISTAHSVFSPSVVNEIIEPTVRDIANNARGEVVSLGFLISLWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AISAFVD+VVEAHDQTPLRHPVRQRFFALFLYVVMLV +VATAP++VVGPRKV EHIP  
Sbjct  121  AISAFVDSVVEAHDQTPLRHPVRQRFFALFLYVVMLVGVVATAPLVVVGPRKVGEHIPLG  180

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
            L+N+LRYGYYPALI+GLT+ V++LYRVALP PLP+HRL+LGA+LA  VF+ ATLGLR YL
Sbjct  181  LSNVLRYGYYPALIVGLTIAVMILYRVALPEPLPSHRLILGAMLATTVFVTATLGLRFYL  240

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
             WIT TGYTYGAL+TPIAFLLFAFFGGFAIMLGAELNAAVQEE+PAP THAHRL  WL +
Sbjct  241  RWITSTGYTYGALSTPIAFLLFAFFGGFAIMLGAELNAAVQEEFPAPKTHAHRLRTWLFS  300

Query  301  R  301
            R
Sbjct  301  R  301


>gi|342858425|ref|ZP_08715080.1| hypothetical protein MCOL_06106 [Mycobacterium colombiense CECT 
3035]
 gi|342134129|gb|EGT87309.1| hypothetical protein MCOL_06106 [Mycobacterium colombiense CECT 
3035]
Length=334

 Score =  444 bits (1142),  Expect = 8e-123, Method: Compositional matrix adjust.
 Identities = 254/333 (77%), Positives = 281/333 (85%), Gaps = 10/333 (3%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MS+QV KP RHHIWRIT RTLSKSWDDSIFSESAQA FWSALSLPPLLLG+LG+LAYVAP
Sbjct  1    MSEQVAKPSRHHIWRITLRTLSKSWDDSIFSESAQAGFWSALSLPPLLLGLLGTLAYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFGPD LP+I +  +STAHS FS SVVNEIIEPT+ DI NNARGEV SLGF+ISLWAGSS
Sbjct  61   LFGPDMLPSILRQLISTAHSVFSRSVVNEIIEPTVRDIANNARGEVVSLGFIISLWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AISAFVD+VVEAHDQTPLRHPVRQR FALFLYVV LVF+VATAP++V+GPRKV EHIP  
Sbjct  121  AISAFVDSVVEAHDQTPLRHPVRQRLFALFLYVVGLVFVVATAPLVVMGPRKVGEHIPLG  180

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
            LAN+LRYGYYPALIL L  GV++LYRV+LP PLPTHRL+ GA LA AVF+IATLGLRVYL
Sbjct  181  LANVLRYGYYPALILALMFGVVILYRVSLPEPLPTHRLIFGAALATAVFVIATLGLRVYL  240

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
             WIT TGYTYGAL+TPIAFLLF+FFGGFAIM+GAELNAA+QEE+PAP THAHRL  WL +
Sbjct  241  QWITSTGYTYGALSTPIAFLLFSFFGGFAIMIGAELNAAIQEEFPAPRTHAHRLRRWLLS  300

Query  301  R---IGVGTTTYSS-------TAQHSAVAAEPP  323
            R   +     T S+       TAQ     AEPP
Sbjct  301  RSPALAKAADTLSNPVTKNPITAQRDVAPAEPP  333


>gi|254821654|ref|ZP_05226655.1| hypothetical protein MintA_17092 [Mycobacterium intracellulare 
ATCC 13950]
Length=333

 Score =  437 bits (1124),  Expect = 1e-120, Method: Compositional matrix adjust.
 Identities = 254/332 (77%), Positives = 280/332 (85%), Gaps = 9/332 (2%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MSDQV KP RHHIWRIT R LSKSWDDSIFSESAQA FWSALSLPPLLLGMLG++AYVAP
Sbjct  1    MSDQVAKPSRHHIWRITLRALSKSWDDSIFSESAQAGFWSALSLPPLLLGMLGTMAYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFGPD LP I +  LSTAHS FSPSVVNEIIEPT+ DI +NARGEV SLGF+ISLWAGSS
Sbjct  61   LFGPDMLPNILRQLLSTAHSVFSPSVVNEIIEPTVRDIASNARGEVVSLGFIISLWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AISAFVD+VVEAHDQTPLRHPVRQRFFALFLYVVMLV +VATAP++VVGPRKV EHIP  
Sbjct  121  AISAFVDSVVEAHDQTPLRHPVRQRFFALFLYVVMLVVVVATAPLVVVGPRKVEEHIPLG  180

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
            L+N+LRYGYYPALI+GLT+GV++LYRVALP PLP+HRL+LGA+LA  VF+ ATLGLR YL
Sbjct  181  LSNVLRYGYYPALIIGLTLGVMILYRVALPEPLPSHRLILGAMLATTVFVTATLGLRFYL  240

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
             WIT TGYTYGAL+TPIAFLLFAFFGGFAIMLGAELNAAVQEE+PAP THAHR+  WL +
Sbjct  241  RWITSTGYTYGALSTPIAFLLFAFFGGFAIMLGAELNAAVQEEFPAPTTHAHRVRTWLFS  300

Query  301  RIGVGTTTYSS---------TAQHSAVAAEPP  323
            R      T  +         T Q     A+PP
Sbjct  301  RSPALKKTVETLASPIANPATQQRDTAPAKPP  332


>gi|108799147|ref|YP_639344.1| ribonuclease BN [Mycobacterium sp. MCS]
 gi|119868262|ref|YP_938214.1| ribonuclease BN [Mycobacterium sp. KMS]
 gi|126434755|ref|YP_001070446.1| ribonuclease BN [Mycobacterium sp. JLS]
 gi|108769566|gb|ABG08288.1| ribonuclease BN [Mycobacterium sp. MCS]
 gi|119694351|gb|ABL91424.1| ribonuclease BN [Mycobacterium sp. KMS]
 gi|126234555|gb|ABN97955.1| ribonuclease BN [Mycobacterium sp. JLS]
Length=321

 Score =  393 bits (1009),  Expect = 2e-107, Method: Compositional matrix adjust.
 Identities = 221/303 (73%), Positives = 252/303 (84%), Gaps = 2/303 (0%)

Query  1    MSDQVP--KPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYV  58
            M+DQ P     RHH+ R   RTLSKSWDDSIFSESAQAAFW ALSLPPLLLGMLGSLAY+
Sbjct  1    MTDQPPPVNTTRHHVRRTLVRTLSKSWDDSIFSESAQAAFWCALSLPPLLLGMLGSLAYI  60

Query  59   APLFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAG  118
            APLFGPD LP IE   + TA+SFFS +VVNEII PT+ DI   ARGEV SLGF+ISLWAG
Sbjct  61   APLFGPDVLPTIENQLIRTANSFFSSNVVNEIIAPTVSDIVKGARGEVVSLGFVISLWAG  120

Query  119  SSAISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIP  178
            SSAISAFVD++VEAHDQTPLRHPVRQRF+AL LYVVMLVF V TAP++ +GPRKV+  IP
Sbjct  121  SSAISAFVDSIVEAHDQTPLRHPVRQRFYALGLYVVMLVFAVGTAPLLALGPRKVAALIP  180

Query  179  ESLANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRV  238
            +    +LR+GY+PAL L L V V +LYRV+LP PLP+HRL+LG++LA  VFL+ TLGLRV
Sbjct  181  DEWDAVLRFGYWPALFLSLLVAVNILYRVSLPKPLPSHRLILGSILATVVFLVTTLGLRV  240

Query  239  YLAWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWL  298
            YL WIT TGYTYGALATPIAFLLFAFF GFAIM+GAELNAAV+E+WPAP+THA R   WL
Sbjct  241  YLTWITSTGYTYGALATPIAFLLFAFFLGFAIMIGAELNAAVEEQWPAPSTHARRAKVWL  300

Query  299  KAR  301
            + R
Sbjct  301  EER  303


>gi|118471083|ref|YP_887086.1| hypothetical protein MSMEG_2755 [Mycobacterium smegmatis str. 
MC2 155]
 gi|118172370|gb|ABK73266.1| conserved hypothetical protein [Mycobacterium smegmatis str. 
MC2 155]
Length=330

 Score =  392 bits (1008),  Expect = 3e-107, Method: Compositional matrix adjust.
 Identities = 222/319 (70%), Positives = 257/319 (81%), Gaps = 2/319 (0%)

Query  8    PHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTL  67
            P RHHI  I +RTLSKSWDDSIFSESAQAAFW ALSLPPLLLGMLGSLAY+APLFGP+TL
Sbjct  10   PSRHHIRHIAKRTLSKSWDDSIFSESAQAAFWCALSLPPLLLGMLGSLAYIAPLFGPETL  69

Query  68   PAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVD  127
            P I+   ++ A+SFFSP+VVNEIIEPTI DI   ARGEV S+GF+ISLWAGSSA+SAFVD
Sbjct  70   PTIQNQLITAANSFFSPNVVNEIIEPTIRDIVKGARGEVVSIGFVISLWAGSSAVSAFVD  129

Query  128  AVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLANLLRY  187
            ++VEAHDQTPLRHPVRQRF+AL LYVVMLV  +A AP++ +GPRK++E +P+S  N L Y
Sbjct  130  SIVEAHDQTPLRHPVRQRFYALGLYVVMLVGAIAAAPLVALGPRKIAEQLPDSWDNALHY  189

Query  188  GYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTG  247
            GYYPAL   + + V +LYRV+LP PLPTHRL+LG VLA  VFL+ T+GLRVYL WIT TG
Sbjct  190  GYYPALFFAVALFVTVLYRVSLPEPLPTHRLLLGTVLATVVFLVTTVGLRVYLTWITSTG  249

Query  248  YTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKARIGVGTT  307
            YTYGALATPIAFLLFAFF GFAIM+GAELNAA+QEEWPA  THA R+  W++ R   G  
Sbjct  250  YTYGALATPIAFLLFAFFLGFAIMIGAELNAAIQEEWPAADTHATRVRKWIETRTRNGGA  309

Query  308  TYSSTAQHSAV--AAEPPS  324
                  +   V  AAE PS
Sbjct  310  EEPVRDEPDPVPGAAEEPS  328


>gi|333991089|ref|YP_004523703.1| hypothetical protein JDM601_2450 [Mycobacterium sp. JDM601]
 gi|333487058|gb|AEF36450.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=319

 Score =  392 bits (1007),  Expect = 4e-107, Method: Compositional matrix adjust.
 Identities = 221/303 (73%), Positives = 252/303 (84%), Gaps = 0/303 (0%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            M+DQ+PKP RHH+ RI RRTL KSWDDSIF+ESAQA FWS LSLPPLLLGMLGSL+YVAP
Sbjct  1    MADQIPKPSRHHLLRIARRTLVKSWDDSIFAESAQAGFWSVLSLPPLLLGMLGSLSYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFGPDTL  I+   +  A SFFS +VV EIIEPT+ DI +NARGEV SLGF+ISLWAGSS
Sbjct  61   LFGPDTLATIQDRLIGMASSFFSQNVVVEIIEPTVRDIVSNARGEVVSLGFVISLWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AISAFVD+VVEAHDQTPLRHPVRQRFFAL LYV MLV  VA AP   +GP  ++EH+P  
Sbjct  121  AISAFVDSVVEAHDQTPLRHPVRQRFFALGLYVAMLVIAVAGAPFAALGPHAIAEHLPAR  180

Query  181  LANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
              +LLR+GYYP L+LGL + V +LYRV+LP PLP+HRLV+GA+LA  VF++ATLGLRVYL
Sbjct  181  WTDLLRFGYYPTLVLGLLLAVTVLYRVSLPKPLPSHRLVIGALLATTVFVVATLGLRVYL  240

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
             +IT TGYTYGALATPIAFLLFAF  GFAIMLGAELNAA+QEEWPA ATH  +L  WL +
Sbjct  241  RYITSTGYTYGALATPIAFLLFAFLLGFAIMLGAELNAAIQEEWPAEATHLRQLRVWLVS  300

Query  301  RIG  303
            R G
Sbjct  301  RTG  303


>gi|120403444|ref|YP_953273.1| ribonuclease BN [Mycobacterium vanbaalenii PYR-1]
 gi|119956262|gb|ABM13267.1| ribonuclease BN [Mycobacterium vanbaalenii PYR-1]
Length=344

 Score =  381 bits (979),  Expect = 8e-104, Method: Compositional matrix adjust.
 Identities = 222/310 (72%), Positives = 251/310 (81%), Gaps = 0/310 (0%)

Query  4    QVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFG  63
            Q  +P RHHI  IT R LSKSWDDSIFSESAQAAFW ALSLPPLLLGMLGSLAYVAPLFG
Sbjct  14   QRARPSRHHIRHITIRALSKSWDDSIFSESAQAAFWCALSLPPLLLGMLGSLAYVAPLFG  73

Query  64   PDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAIS  123
            PDTL  I+   +S A  FFSP+VV+EIIEPT+ DI   ARGEV SLGF+ISLWAGSSAIS
Sbjct  74   PDTLVTIQSQLVSLAGRFFSPNVVSEIIEPTVRDIVRGARGEVVSLGFVISLWAGSSAIS  133

Query  124  AFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLAN  183
            AFVD++ EAHDQTPLRHPVRQRF+AL LYVVMLV  +  AP + +GPRKV+E IP+S  +
Sbjct  134  AFVDSITEAHDQTPLRHPVRQRFYALGLYVVMLVGAIVAAPFLALGPRKVAEFIPDSWDS  193

Query  184  LLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWI  243
             L++ YYP L + L V V LLYRV+LP PLP+HRL+LG+VLA AVFLIAT GLRVYL WI
Sbjct  194  ALQFAYYPVLFVALVVSVNLLYRVSLPKPLPSHRLLLGSVLAAAVFLIATWGLRVYLTWI  253

Query  244  TRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKARIG  303
            T TGYTYGALATPIAFLLFAFF GFAIM+GAELNAA++EE+PAP THA R   WL+A+  
Sbjct  254  TSTGYTYGALATPIAFLLFAFFLGFAIMIGAELNAAIEEEFPAPDTHAKRFRWWLEAKAE  313

Query  304  VGTTTYSSTA  313
                T S TA
Sbjct  314  SLNGTTSPTA  323


>gi|145224526|ref|YP_001135204.1| ribonuclease BN [Mycobacterium gilvum PYR-GCK]
 gi|315444857|ref|YP_004077736.1| hypothetical protein Mspyr1_32900 [Mycobacterium sp. Spyr1]
 gi|145217012|gb|ABP46416.1| ribonuclease BN [Mycobacterium gilvum PYR-GCK]
 gi|315263160|gb|ADT99901.1| predicted membrane protein [Mycobacterium sp. Spyr1]
Length=323

 Score =  376 bits (965),  Expect = 3e-102, Method: Compositional matrix adjust.
 Identities = 214/294 (73%), Positives = 242/294 (83%), Gaps = 0/294 (0%)

Query  8    PHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTL  67
            P RHHI  I  RTL KSWDDSIF+ESAQAAFW ALSLPPLLLGMLGSLAYVAPLFGPDTL
Sbjct  18   PSRHHIRHIVARTLGKSWDDSIFAESAQAAFWCALSLPPLLLGMLGSLAYVAPLFGPDTL  77

Query  68   PAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVD  127
              IE   +S A  FFSP+VV EIIEPT+ DI N ARGEV SLGF+ISLWAGSSAISAFVD
Sbjct  78   LTIENQLISLAGKFFSPNVVGEIIEPTVRDIVNGARGEVVSLGFVISLWAGSSAISAFVD  137

Query  128  AVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLANLLRY  187
            ++ EAH QT LRHPVRQRF+AL LYVVML+  + TAP + +GPRKV+E IP+S  + LR+
Sbjct  138  SITEAHGQTALRHPVRQRFYALGLYVVMLIGAIVTAPFLALGPRKVAEFIPDSWDDALRF  197

Query  188  GYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTG  247
             Y+P L + L V V +LYRV+LP PLPTHRL+ G++LA  VFL+AT GLRVYL WIT TG
Sbjct  198  AYFPVLFVALAVAVNVLYRVSLPKPLPTHRLLTGSLLAAGVFLVATWGLRVYLTWITSTG  257

Query  248  YTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKAR  301
            YTYGALATPIAFLLFAFF GFAIM+GAELNAA++EEWPAP THA RL  WLKA+
Sbjct  258  YTYGALATPIAFLLFAFFLGFAIMIGAELNAAIEEEWPAPDTHAKRLHWWLKAK  311


>gi|169630108|ref|YP_001703757.1| ribonuclease BN [Mycobacterium abscessus ATCC 19977]
 gi|169242075|emb|CAM63103.1| Possible ribonuclease BN [Mycobacterium abscessus]
Length=320

 Score =  363 bits (933),  Expect = 1e-98, Method: Compositional matrix adjust.
 Identities = 194/288 (68%), Positives = 231/288 (81%), Gaps = 0/288 (0%)

Query  16   ITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSAL  75
            + RRT  KSWDDSIF++SAQAAFW  LSLPPLLLG+LGSL +V PLFGPDTLP I++  +
Sbjct  17   VMRRTAVKSWDDSIFAQSAQAAFWQVLSLPPLLLGILGSLTFVGPLFGPDTLPEIQERLV  76

Query  76   STAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQ  135
              A+S FS SVV EIIEPTI DI  + RGEV S+GF+ISLWAGSSAIS+FVD+VVEAHDQ
Sbjct  77   RVANSVFSKSVVTEIIEPTIIDIMRDGRGEVVSIGFVISLWAGSSAISSFVDSVVEAHDQ  136

Query  136  TPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLANLLRYGYYPALIL  195
            TPLRHPVRQRFFAL LYV  L   V T P++ +GP++++E +P+S  +LLRYGY+P L +
Sbjct  137  TPLRHPVRQRFFALGLYVAALAMAVVTLPMVALGPKRIAEVVPDSWNSLLRYGYFPLLGI  196

Query  196  GLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTYGALAT  255
             L   V LLYRV+LP PLP+HRL +GA+LA+  F IA+LGLR YL WIT TGYTYGALAT
Sbjct  197  ALVALVTLLYRVSLPRPLPSHRLWIGALLAVTFFAIASLGLRFYLNWITGTGYTYGALAT  256

Query  256  PIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKARIG  303
            PIAFLLFAF  GFAI+LGAELNAA++E WPA ATHA +L  WL  + G
Sbjct  257  PIAFLLFAFMLGFAIVLGAELNAAIEENWPAGATHARQLREWLSPQNG  304


>gi|289444249|ref|ZP_06433993.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
 gi|289417168|gb|EFD14408.1| conserved hypothetical protein [Mycobacterium tuberculosis T46]
Length=172

 Score =  338 bits (867),  Expect = 7e-91, Method: Compositional matrix adjust.
 Identities = 168/168 (100%), Positives = 168/168 (100%), Gaps = 0/168 (0%)

Query  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP
Sbjct  1    MSDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
            LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS
Sbjct  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVV  168
            AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVV
Sbjct  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVV  168


>gi|317506481|ref|ZP_07964282.1| ribonuclease BN family protein [Segniliparus rugosus ATCC BAA-974]
 gi|316255242|gb|EFV14511.1| ribonuclease BN family protein [Segniliparus rugosus ATCC BAA-974]
Length=345

 Score =  276 bits (705),  Expect = 4e-72, Method: Compositional matrix adjust.
 Identities = 145/275 (53%), Positives = 189/275 (69%), Gaps = 4/275 (1%)

Query  15   RITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSA  74
            R+  R L+ SW+ SIF+ESA AAFW  LSLPP+ LG+LG+L YV+P FGP  L  ++   
Sbjct  21   RVVTRALAMSWEHSIFAESAGAAFWQILSLPPMFLGLLGTLGYVSPWFGPGVLEDVQHKI  80

Query  75   LSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHD  134
            L+ A    S  +VNE+I PT+  +T + R EV SL F++SLWAGSSAISAFVD++V AH+
Sbjct  81   LAFAQQALSQQLVNEVIRPTLMAVTAHGREEVTSLSFVLSLWAGSSAISAFVDSIVRAHN  140

Query  135  QTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLANLLRYGYY----  190
            QT LRHPVRQR FAL LY+V L   +   P++ V P +V+  +P+    +L   Y     
Sbjct  141  QTELRHPVRQRIFALGLYIVFLACAMFALPLLSVTPHEVTTRLPQETHPVLSSAYNDLYG  200

Query  191  PALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTY  250
            PAL +G+T+ +   YR+ALPVP    RLV GAVLA+  FL+   GL  YL W+T TGYTY
Sbjct  201  PALFVGVTLFLSWFYRIALPVPPSWWRLVPGAVLAVLFFLVGRSGLLWYLNWVTSTGYTY  260

Query  251  GALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWP  285
            GALATPIA LL AFF G +++LGAELN+A++  WP
Sbjct  261  GALATPIAMLLLAFFIGMSVILGAELNSAIEHFWP  295


>gi|333919429|ref|YP_004493010.1| hypothetical protein AS9A_1761 [Amycolicicoccus subflavus DQS3-9A1]
 gi|333481650|gb|AEF40210.1| Conserved hypothetical membrane protein [Amycolicicoccus subflavus 
DQS3-9A1]
Length=378

 Score =  276 bits (705),  Expect = 4e-72, Method: Compositional matrix adjust.
 Identities = 171/302 (57%), Positives = 207/302 (69%), Gaps = 11/302 (3%)

Query  8    PHRHHIWRITRRTLS-------KSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAP  60
            P R H W   RRT         K+WDDSIFS SA AAFW  LSLPPL LG+LG L YV  
Sbjct  13   PARAHRWHPIRRTGQVIGRTTVKAWDDSIFSHSATAAFWQVLSLPPLFLGVLGMLGYVGD  72

Query  61   LFGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSS  120
             FGP+T+  IE   ++ + + F+ SVV++II+PT+ D+    R E  S+GF++SLWAGSS
Sbjct  73   WFGPNTIDIIEGKIITFSGAVFNESVVDQIIQPTVNDVLVRGRLEFVSVGFVLSLWAGSS  132

Query  121  AISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES  180
            AISAFVDA+VEAH Q   RHPV QR FAL LYVV L   V T P++ +GP  + + IP+S
Sbjct  133  AISAFVDAIVEAHGQNEHRHPVWQRLFALLLYVVFLFLAVFTMPLVALGPALIMDLIPDS  192

Query  181  L----ANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGL  236
                 + ++R  YYPA+ + L  G+  LY+VALP  LP HRL+ GAVLA  VF  A+ GL
Sbjct  193  WDHLGSEMVRTFYYPAVAVLLLFGLTTLYKVALPRSLPWHRLLAGAVLAGVVFYAASTGL  252

Query  237  RVYLAWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGN  296
            RVYL  ITRTGYTYGALATPIAFLLFAFF GFAIMLGAE NA +QE WPA AT   ++  
Sbjct  253  RVYLGAITRTGYTYGALATPIAFLLFAFFLGFAIMLGAEFNATIQEIWPARATRIEQVRR  312

Query  297  WL  298
            WL
Sbjct  313  WL  314


>gi|296393380|ref|YP_003658264.1| ribonuclease BN [Segniliparus rotundus DSM 44985]
 gi|296180527|gb|ADG97433.1| ribonuclease BN [Segniliparus rotundus DSM 44985]
Length=344

 Score =  270 bits (690),  Expect = 2e-70, Method: Compositional matrix adjust.
 Identities = 142/275 (52%), Positives = 183/275 (67%), Gaps = 4/275 (1%)

Query  15   RITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSA  74
            R+  RTLS SW+ SIF+ESA AAFW  LSL P+ LG+LG+L YV P FGP  L  ++   
Sbjct  9    RVLGRTLSMSWEHSIFAESAGAAFWQILSLTPMFLGLLGTLGYVCPWFGPGVLEDVQHKI  68

Query  75   LSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHD  134
            LS A    S  +VNE+I PT+  +T N R  V S  FL+SLWAGSSAISAFVD++V AHD
Sbjct  69   LSFAQQALSQKLVNEVIRPTLLAVTANGREAVTSFSFLLSLWAGSSAISAFVDSIVRAHD  128

Query  135  QTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES----LANLLRYGYY  190
            QT LRHPVRQR +AL LY+V L+  +   P++ V P +V+  +P      ++++    Y 
Sbjct  129  QTELRHPVRQRIYALILYIVFLLSAMFALPILSVAPHQVTMRLPIETHPLVSSVYNNLYG  188

Query  191  PALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTY  250
            P L + + + +   Y +ALPVP P HRL+ GA+LA+  FL    GL  YL W+T TGYTY
Sbjct  189  PGLFVAVALFLAWFYHIALPVPPPWHRLIPGALLAVMFFLAGRSGLLWYLNWVTSTGYTY  248

Query  251  GALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWP  285
            GALATPIA LL AFF G A++ GAELN+ V+  WP
Sbjct  249  GALATPIALLLVAFFLGMAVIAGAELNSTVEHFWP  283


>gi|229491263|ref|ZP_04385089.1| ribonuclease BN [Rhodococcus erythropolis SK121]
 gi|229321802|gb|EEN87597.1| ribonuclease BN [Rhodococcus erythropolis SK121]
Length=420

 Score =  259 bits (662),  Expect = 5e-67, Method: Compositional matrix adjust.
 Identities = 155/287 (55%), Positives = 202/287 (71%), Gaps = 4/287 (1%)

Query  19   RTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSALSTA  78
            RTLSK+WDDSIF ++A AAFW  LSL PLLLG+LG + Y+   FGP+T+  IE   ++ +
Sbjct  31   RTLSKAWDDSIFGKAATAAFWQTLSLAPLLLGLLGMIGYIGGWFGPNTVEIIESKIVTFS  90

Query  79   HSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQTPL  138
             + FS SVV++II PT+ D+    R E+ S+GFL+SLWAGSSAIS FVD++VEAH Q   
Sbjct  91   GTIFSESVVDQIIRPTVTDVLQRGRPEIISVGFLLSLWAGSSAISTFVDSIVEAHGQQDA  150

Query  139  RHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESL----ANLLRYGYYPALI  194
            R+P+ QR FAL LYV+ LV  V   P++ +GP  V   +P S     +NL+   YYPA+ 
Sbjct  151  RNPIWQRIFALLLYVMFLVMAVFILPLVALGPTLVGRALPASWYVVGSNLVDTFYYPAVG  210

Query  195  LGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTYGALA  254
            L + +G+  LY+VALP  LP HRL+ GA++A   F+ A+ GLR YL ++T TGYTYGALA
Sbjct  211  LLVIIGLTTLYKVALPKSLPWHRLLAGALVAGVFFMAASTGLRWYLGFVTSTGYTYGALA  270

Query  255  TPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKAR  301
            TPIAFLLF FF GFA++LGAE NA VQE WPA AT   ++  WL A+
Sbjct  271  TPIAFLLFTFFLGFAVVLGAEFNATVQEFWPARATRMEQMREWLAAQ  317


>gi|226306295|ref|YP_002766255.1| hypothetical protein RER_28080 [Rhodococcus erythropolis PR4]
 gi|226185412|dbj|BAH33516.1| conserved hypothetical membrane protein [Rhodococcus erythropolis 
PR4]
Length=415

 Score =  258 bits (660),  Expect = 7e-67, Method: Compositional matrix adjust.
 Identities = 155/287 (55%), Positives = 202/287 (71%), Gaps = 4/287 (1%)

Query  19   RTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSALSTA  78
            RTLSK+WDDSIF ++A AAFW  LSL PLLLG+LG + Y+   FGP+T+  IE   ++ +
Sbjct  31   RTLSKAWDDSIFGKAATAAFWQTLSLAPLLLGLLGMIGYIGGWFGPNTVEIIESKIVTFS  90

Query  79   HSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQTPL  138
             + FS SVV++II PT+ D+    R E+ S+GFL+SLWAGSSAIS FVD++VEAH Q   
Sbjct  91   GTIFSESVVDQIIRPTVTDVLQRGRPEIISVGFLLSLWAGSSAISTFVDSIVEAHGQQDA  150

Query  139  RHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESL----ANLLRYGYYPALI  194
            R+P+ QR FAL LYV+ LV  V   P++ +GP  V   +P S     +NL+   YYPA+ 
Sbjct  151  RNPIWQRIFALLLYVMFLVMAVFILPLVALGPTLVGRALPASWYVVGSNLVDTFYYPAVG  210

Query  195  LGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTYGALA  254
            L + +G+  LY+VALP  LP HRL+ GA++A   F+ A+ GLR YL ++T TGYTYGALA
Sbjct  211  LLVIIGLTTLYKVALPKSLPWHRLLAGALVAGVFFMAASTGLRWYLGFVTSTGYTYGALA  270

Query  255  TPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKAR  301
            TPIAFLLF FF GFA++LGAE NA VQE WPA AT   ++  WL A+
Sbjct  271  TPIAFLLFTFFLGFAVVLGAEFNATVQEFWPARATRMEQMREWLAAQ  317


>gi|300784486|ref|YP_003764777.1| ribonuclease BN [Amycolatopsis mediterranei U32]
 gi|299794000|gb|ADJ44375.1| ribonuclease BN [Amycolatopsis mediterranei U32]
 gi|340525907|gb|AEK41112.1| ribonuclease BN [Amycolatopsis mediterranei S699]
Length=384

 Score =  253 bits (647),  Expect = 2e-65, Method: Compositional matrix adjust.
 Identities = 147/287 (52%), Positives = 198/287 (69%), Gaps = 4/287 (1%)

Query  7    KPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDT  66
            K  R   WR+  RT +K+W+ +IFSE+A+AAFW  LSLPPLLLG+LGSL +V   FG D 
Sbjct  11   KVARKGPWRLVTRTFAKAWEGNIFSEAAEAAFWQTLSLPPLLLGLLGSLGFVGEWFGQDV  70

Query  67   LPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFV  126
            + A+    +    + FS + V++IIEPT+  I    +GE+ S+GFLISLWAGSSA+S+FV
Sbjct  71   VAAVHDRIIGFCRTVFSANAVHDIIEPTVNSILTVGKGEIVSVGFLISLWAGSSAMSSFV  130

Query  127  DAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPE----SLA  182
            DA+  AHDQ  +R+ V QR FAL LY+  LV LV   P++ +GP  + E  P     ++ 
Sbjct  131  DAITVAHDQYGVRNDVWQRIFALLLYLCGLVILVVGLPLLAIGPDLLPEFFPTAWRPTVT  190

Query  183  NLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAW  242
            + +   Y+PAL   +T+ +  LY++ALP  LP HR + GAVLA+ VFL++++GLRVYL W
Sbjct  191  SWVSALYFPALGAMITLALTTLYKLALPRKLPWHRGLPGAVLAMVVFLLSSVGLRVYLNW  250

Query  243  ITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPAT  289
            IT+TGYTYGALA PIAFLL  FF G A++ GA  N+A+QE WPA AT
Sbjct  251  ITKTGYTYGALAAPIAFLLLMFFIGLAVVGGAYFNSAIQELWPAKAT  297


>gi|302525720|ref|ZP_07278062.1| ribonuclease BN [Streptomyces sp. AA4]
 gi|302434615|gb|EFL06431.1| ribonuclease BN [Streptomyces sp. AA4]
Length=412

 Score =  251 bits (642),  Expect = 9e-65, Method: Compositional matrix adjust.
 Identities = 143/287 (50%), Positives = 200/287 (70%), Gaps = 4/287 (1%)

Query  7    KPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDT  66
            K  R   WR+  RTL+K+WD +IFSE+A+AAFW  LSLPPLLLG+LGS+ ++   FG + 
Sbjct  26   KTVRRGPWRLLTRTLAKAWDGNIFSEAAEAAFWQTLSLPPLLLGLLGSVGFIGEWFGQNV  85

Query  67   LPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFV  126
            + A+    ++ +H+ FS + V EIIEPT+  I    +GE+ S+GF+ISLWAGSSA+S+FV
Sbjct  86   VTAVHDRIITFSHTIFSANAVQEIIEPTVNSILTVGKGEIVSVGFVISLWAGSSAMSSFV  145

Query  127  DAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIP----ESLA  182
            DA+  AHDQ  +R+ V QR FAL LY+  L+ LV   P++ +GP  + E  P     +++
Sbjct  146  DAITVAHDQYGVRNEVWQRIFALLLYLCALIGLVIGLPLLAIGPDLLPEFFPVDWRPTVS  205

Query  183  NLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAW  242
            + +   YYP L + + + +  LY++ALP  LP HR + GA+LA  VFL++++GLR+YL W
Sbjct  206  SWVGTLYYPVLGVMIALALTTLYKLALPRRLPWHRGLPGAMLAGVVFLVSSIGLRIYLNW  265

Query  243  ITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPAT  289
            IT+TGYTYGALA PIAFLL  FF G A++ GA  N+A+QE WPA AT
Sbjct  266  ITKTGYTYGALAAPIAFLLLMFFIGLAVVGGAYFNSAIQELWPAKAT  312


>gi|111023775|ref|YP_706747.1| hypothetical protein RHA1_ro06817 [Rhodococcus jostii RHA1]
 gi|110823305|gb|ABG98589.1| conserved hypothetical protein [Rhodococcus jostii RHA1]
Length=390

 Score =  250 bits (638),  Expect = 2e-64, Method: Compositional matrix adjust.
 Identities = 162/303 (54%), Positives = 207/303 (69%), Gaps = 7/303 (2%)

Query  6    PKPHRHHIWR---ITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLF  62
            P+P  H + R   +  RT SK+WDDSIF ++A AAFW  LSLPPLLLG+LG L YV   F
Sbjct  16   PRPGWHPLRRALSVIGRTASKAWDDSIFGKAATAAFWQTLSLPPLLLGLLGMLGYVGGWF  75

Query  63   GPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAI  122
            GPDT+  I+   ++ + + FS SVV +II PT+GD+    R E+ SL FL+SLWAGSSAI
Sbjct  76   GPDTVDIIQSKIINFSGTVFSDSVVEQIIRPTVGDVLERGRPEIVSLSFLLSLWAGSSAI  135

Query  123  SAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESL-  181
            S FVD++VEAH Q   RHPV QR FAL LYV+ L+  V T P++ +GP  V   +PE+  
Sbjct  136  STFVDSIVEAHGQQEARHPVWQRVFALLLYVMFLILAVFTLPLVALGPTLVGRVLPEAWR  195

Query  182  ---ANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRV  238
                 ++   YYP + L L VG+  LY+VALP  LP HRL+ GA++A   FL A+  LR 
Sbjct  196  TIGTEIVDTFYYPGVGLLLIVGLTTLYKVALPRSLPWHRLLGGALVAGVFFLGASTCLRR  255

Query  239  YLAWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWL  298
            YL+W+  TGYTYGALATPIAFLLF FF GFA++LGAE NA VQE WPA AT   ++ +W+
Sbjct  256  YLSWVAGTGYTYGALATPIAFLLFTFFLGFAVVLGAEFNATVQEFWPARATRIDQMRDWI  315

Query  299  KAR  301
             A+
Sbjct  316  AAQ  318


>gi|226366211|ref|YP_002783994.1| hypothetical protein ROP_68020 [Rhodococcus opacus B4]
 gi|226244701|dbj|BAH55049.1| hypothetical membrane protein [Rhodococcus opacus B4]
Length=390

 Score =  248 bits (634),  Expect = 7e-64, Method: Compositional matrix adjust.
 Identities = 159/287 (56%), Positives = 200/287 (70%), Gaps = 4/287 (1%)

Query  19   RTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSALSTA  78
            RT SK+WDDSIF ++A AAFW  LSLPPLLLG+LG L YV   FGPDT+  I+   ++ +
Sbjct  32   RTASKAWDDSIFGKAATAAFWQTLSLPPLLLGLLGMLGYVGGWFGPDTVDIIQSKIVNFS  91

Query  79   HSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQTPL  138
             + FS SVV +II PT+GD+    R E+ SL FL+SLWAGSSAIS FVD++VEAH Q   
Sbjct  92   GTVFSDSVVEQIIRPTVGDVLERGRPEIVSLSFLLSLWAGSSAISTFVDSIVEAHGQQEA  151

Query  139  RHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESL----ANLLRYGYYPALI  194
            RHPV QR FAL LYV+ L+  V T P++ +GP  V   +PES       ++   YYP + 
Sbjct  152  RHPVWQRVFALLLYVMFLILAVFTLPLVALGPTLVGRVLPESWRTIGTEIVDTFYYPGVG  211

Query  195  LGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTYGALA  254
            L L VG+  LY+VALP  LP HRL+ GA++A   FL A+  LR YL+W+  TGYTYGALA
Sbjct  212  LLLIVGLTTLYKVALPRSLPWHRLLGGALVAGVFFLGASTCLRRYLSWVAGTGYTYGALA  271

Query  255  TPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKAR  301
            TPIAFLLF FF GFA++LGAE NA VQE WPA AT   ++ +W+ A+
Sbjct  272  TPIAFLLFTFFLGFAVVLGAEFNATVQEFWPARATRIDQMRDWIAAQ  318


>gi|312139428|ref|YP_004006764.1| ribonuclease bn [Rhodococcus equi 103S]
 gi|325672683|ref|ZP_08152379.1| ribonuclease BN [Rhodococcus equi ATCC 33707]
 gi|311888767|emb|CBH48079.1| putative ribonuclease BN [Rhodococcus equi 103S]
 gi|325556560|gb|EGD26226.1| ribonuclease BN [Rhodococcus equi ATCC 33707]
Length=369

 Score =  248 bits (634),  Expect = 8e-64, Method: Compositional matrix adjust.
 Identities = 161/304 (53%), Positives = 210/304 (70%), Gaps = 6/304 (1%)

Query  7    KPHR--HHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGP  64
            K HR      ++  RT SK+WDDSIF +SA AAFW  LSLPPLLLG+LGSL YV   FGP
Sbjct  8    KKHRPFKRCAQVVGRTASKAWDDSIFGKSATAAFWQTLSLPPLLLGLLGSLGYVGGWFGP  67

Query  65   DTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISA  124
            +T+  I+   ++ +H+ FS +VV++II+PT+GD+    R E+ S+GFL+SLWAGSSAIS 
Sbjct  68   NTVEIIQSKIITFSHTVFSENVVDQIIQPTVGDVLGRGRPEIISVGFLLSLWAGSSAIST  127

Query  125  FVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESL---  181
            FVD++VEAH Q   RHPV QR FAL LYV  L+  V T P++ +GP  +   +PES    
Sbjct  128  FVDSIVEAHGQQDARHPVWQRVFALLLYVGFLILAVFTLPLVALGPTIIGRVLPESWHTV  187

Query  182  -ANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYL  240
               ++   YYPA+ L L +G+  LY+VALP  LP HRL+ GA+LA   F+ A+  LR YL
Sbjct  188  GTEMVDAFYYPAVGLLLIIGLTTLYKVALPKSLPWHRLLGGALLAGVFFMAASTILRWYL  247

Query  241  AWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKA  300
            + I  TGYTYGALATPIAFLLF FF GFA++LGAE NA +QE WPA AT   ++ +W+ A
Sbjct  248  SAIAGTGYTYGALATPIAFLLFTFFLGFAVVLGAEFNATIQEFWPARATRMEQVRDWIAA  307

Query  301  RIGV  304
            +  +
Sbjct  308  QAAI  311


>gi|296139552|ref|YP_003646795.1| ribonuclease BN [Tsukamurella paurometabola DSM 20162]
 gi|296027686|gb|ADG78456.1| ribonuclease BN [Tsukamurella paurometabola DSM 20162]
Length=404

 Score =  240 bits (613),  Expect = 2e-61, Method: Compositional matrix adjust.
 Identities = 155/288 (54%), Positives = 199/288 (70%), Gaps = 4/288 (1%)

Query  15   RITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSA  74
            RI  RT+ KSWDDSI  +SAQAAFW  LSLPPLLLG+LG   YVA  FGPDT+  I+   
Sbjct  43   RIFWRTIVKSWDDSIIGQSAQAAFWQTLSLPPLLLGLLGLTGYVANWFGPDTIGVIQGKI  102

Query  75   LSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHD  134
            LS + S F+ SVV EII P +  + +  R ++ S+GF+I+LWAGSSA+S+FVD++  AHD
Sbjct  103  LSFSESVFTESVVTEIIGPMVSGVLSEGRFDIVSIGFIIALWAGSSALSSFVDSICMAHD  162

Query  135  QTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES----LANLLRYGYY  190
            Q  +R+PV QRFFA+ LYV  LV  V T P++ +GP  + +++P S    +A L+  GY 
Sbjct  163  QHTVRNPVHQRFFAVLLYVEFLVIAVLTLPLVALGPTLIVKYMPASWHPAVARLIDVGYL  222

Query  191  PALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTY  250
            P ++  L   + LLYR ALP PLP +R V GA LA  +FLIA+ GLRVYL+ I   GY+Y
Sbjct  223  PFVVALLVGALALLYRQALPRPLPWYRQVPGAALAALIFLIASTGLRVYLSLIATRGYSY  282

Query  251  GALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWL  298
            GALATPIAFLLF FF GFA+M+GAE NAA+Q  WPA      +L  W+
Sbjct  283  GALATPIAFLLFTFFLGFAVMVGAEFNAALQARWPAREVRTDQLRGWV  330


>gi|256375638|ref|YP_003099298.1| ribonuclease BN [Actinosynnema mirum DSM 43827]
 gi|255919941|gb|ACU35452.1| ribonuclease BN [Actinosynnema mirum DSM 43827]
Length=431

 Score =  236 bits (603),  Expect = 3e-60, Method: Compositional matrix adjust.
 Identities = 147/289 (51%), Positives = 196/289 (68%), Gaps = 5/289 (1%)

Query  2    SDQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPL  61
             D    P R  + R+  RT++K+W+ +IFSE+A+AAFW  LS PPLLLG+LGS+ YV   
Sbjct  12   QDDRSAPERRPL-RLVARTITKAWEGNIFSEAAEAAFWQVLSFPPLLLGLLGSIGYVGEW  70

Query  62   FGPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSA  121
            FGP+ + A+    +ST  + FS  VVN +I PT+  I    +GE+ S+GFLISLWAGSSA
Sbjct  71   FGPEVVQAVRDKIVSTCRTIFSGDVVNGVITPTVDQILTVGKGEIVSVGFLISLWAGSSA  130

Query  122  ISAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESL  181
            +++FVDAV  AH Q  +RH V QR FAL LYVV LV L+   PV+ +GP  +   +P+  
Sbjct  131  MASFVDAVTVAHGQYGVRHEVWQRIFALLLYVVSLVLLIIGLPVLALGPDVLPRFLPDRW  190

Query  182  ANL----LRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLR  237
              +    L   YYP + + L + +  LY++ALP  LP HRL  GA LA+ VF+++++GLR
Sbjct  191  QAVAEAWLSAFYYPVIGVLLVLALATLYKLALPRKLPWHRLAPGAALAMVVFILSSVGLR  250

Query  238  VYLAWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPA  286
            +Y+ WIT TGYTYGALATPIAFLLF FF G AI +GA  N+A+QE WPA
Sbjct  251  LYIRWITTTGYTYGALATPIAFLLFVFFIGLAITIGAYFNSAIQEMWPA  299


>gi|54025740|ref|YP_119982.1| hypothetical protein nfa37700 [Nocardia farcinica IFM 10152]
 gi|54017248|dbj|BAD58618.1| hypothetical protein [Nocardia farcinica IFM 10152]
Length=374

 Score =  234 bits (596),  Expect = 2e-59, Method: Compositional matrix adjust.
 Identities = 153/285 (54%), Positives = 195/285 (69%), Gaps = 4/285 (1%)

Query  22   SKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSALSTAHSF  81
            SK+W DSIF++SA AAFW  LSL PLLLG+LGSL YV   FGPDT+  +E   L+ +   
Sbjct  52   SKAWTDSIFAKSATAAFWQTLSLAPLLLGLLGSLGYVGGWFGPDTVGIVESKILTFSRDL  111

Query  82   FSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQTPLRHP  141
            FS +VV+E+I+PT+ D+    RG V S+GF++SLWAGSSA++ FVDA+VEAHDQ   RHP
Sbjct  112  FSEAVVSELIQPTVTDVLGRGRGAVVSVGFVLSLWAGSSAMATFVDAIVEAHDQQDARHP  171

Query  142  VRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIP----ESLANLLRYGYYPALILGL  197
            V QR FAL LYV  LV  V   P++ +GP  +   +P    E    L+   YYPA+ L L
Sbjct  172  VWQRVFALLLYVQFLVAAVFILPLVALGPSLIGRILPGAWREPGLRLVDSFYYPAVGLLL  231

Query  198  TVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTYGALATPI  257
             VG+  LY+ AL   LP HRL  GA++A   F+ A+ GLR YL+W+T TG +YGALATPI
Sbjct  232  IVGLTTLYKAALHRSLPWHRLFGGALVAGVFFMAASEGLRRYLSWVTATGVSYGALATPI  291

Query  258  AFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKARI  302
            AFLLF FF GFA++LGAE NA VQE WPA AT   ++  WL  ++
Sbjct  292  AFLLFTFFLGFAVILGAEFNATVQEFWPARATRIEQMREWLANQV  336


>gi|257056430|ref|YP_003134262.1| hypothetical protein Svir_24410 [Saccharomonospora viridis DSM 
43017]
 gi|256586302|gb|ACU97435.1| predicted membrane protein [Saccharomonospora viridis DSM 43017]
Length=402

 Score =  232 bits (591),  Expect = 7e-59, Method: Compositional matrix adjust.
 Identities = 144/275 (53%), Positives = 195/275 (71%), Gaps = 4/275 (1%)

Query  19   RTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSALSTA  78
            RTLSK+W+ +IFSE+A+AAFW  LSLPPLLLG+LGSL ++   FG + +       ++ +
Sbjct  32   RTLSKAWNGNIFSEAAEAAFWQTLSLPPLLLGLLGSLGFIGDWFGENVVRQAHDKIIAFS  91

Query  79   HSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQTPL  138
             + FS SVV +II PT+ DI    +GE+ S+GFLISLWAGSSA+S+FVDA+  AHDQ  +
Sbjct  92   DTIFSDSVVQQIIAPTVDDILTTGKGEIVSVGFLISLWAGSSAMSSFVDAITVAHDQYGV  151

Query  139  RHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPE----SLANLLRYGYYPALI  194
            R+ V QR FAL LY+  LV LV   P++ +GP  + E  P+    ++A+ L   YYP + 
Sbjct  152  RNEVWQRIFALLLYLGSLVLLVIGLPIIAIGPDLLPEFFPDDWKPTIASWLSVLYYPTVA  211

Query  195  LGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTYGALA  254
            + L + +  LY++ALP  LP HR + GAVLA+ +FL++++GLR Y++WIT TGYTYGALA
Sbjct  212  VLLVLALATLYKLALPRKLPWHRGLPGAVLAMVIFLLSSVGLRFYISWITTTGYTYGALA  271

Query  255  TPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPAT  289
            TPIAFLLF FF G AI+ GA  N+A+QE WPA  T
Sbjct  272  TPIAFLLFTFFIGLAIVAGAYFNSAIQELWPAKMT  306


>gi|134098374|ref|YP_001104035.1| ribonuclease BN [Saccharopolyspora erythraea NRRL 2338]
 gi|291006924|ref|ZP_06564897.1| ribonuclease BN [Saccharopolyspora erythraea NRRL 2338]
 gi|133910997|emb|CAM01110.1| ribonuclease BN [Saccharopolyspora erythraea NRRL 2338]
Length=404

 Score =  231 bits (590),  Expect = 9e-59, Method: Compositional matrix adjust.
 Identities = 144/287 (51%), Positives = 204/287 (72%), Gaps = 4/287 (1%)

Query  7    KPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDT  66
            +P +    R+  RT++K+W D+IFSESA AAFW  LS+PPLLLG+LGS+ ++A  FGP  
Sbjct  17   RPVKRGPLRLVWRTVTKAWWDNIFSESAAAAFWQTLSMPPLLLGLLGSIGFIADWFGPAV  76

Query  67   LPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFV  126
            + A+  + L  + + FS +VV++II PT+GDI    R E+ S+GFL+SLWAGSSA+++ V
Sbjct  77   IDAVHANILGFSRTVFSGNVVDQIIAPTVGDILTKGRTEIVSVGFLLSLWAGSSALASLV  136

Query  127  DAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGP----RKVSEHIPESLA  182
            D++  A++Q  +RH V QR FAL LY+V LV  V   PV+ +GP    R V +   + +A
Sbjct  137  DSITLAYNQYMVRHSVWQRTFALLLYLVSLVLAVIGLPVIALGPDWLVRVVPQEFQDDVA  196

Query  183  NLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAW  242
             L++  YYPA  + L + +  LY+V+LP  LP HR + GA+LA+ VFL +++G+R+Y+AW
Sbjct  197  WLIQVFYYPATGVLLVLALATLYKVSLPRKLPWHRGLPGALLAMLVFLCSSIGMRLYIAW  256

Query  243  ITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPAT  289
            +T TGYTYGALATPIAFLLFAFF G AI++GA+ N A++E WPA  T
Sbjct  257  VTSTGYTYGALATPIAFLLFAFFIGMAIIIGAQFNNAIEEMWPAKMT  303


>gi|326384456|ref|ZP_08206136.1| ribonuclease BN [Gordonia neofelifaecis NRRL B-59395]
 gi|326196801|gb|EGD53995.1| ribonuclease BN [Gordonia neofelifaecis NRRL B-59395]
Length=325

 Score =  223 bits (567),  Expect = 4e-56, Method: Compositional matrix adjust.
 Identities = 152/311 (49%), Positives = 210/311 (68%), Gaps = 9/311 (2%)

Query  15   RITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSA  74
            R+  RT  KSWDDSI   +AQAAFW ALSLPPLLL +LGSL Y+   FGPDT+  I +  
Sbjct  7    RLAWRTTVKSWDDSIIGWAAQAAFWQALSLPPLLLAVLGSLGYIGGWFGPDTVEIITQRI  66

Query  75   LSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHD  134
            +S +   F+PSVVN++IEPT+ ++    R  + S+ F++SLWAGSSA+S FV ++V AH 
Sbjct  67   ISFSTHAFTPSVVNDLIEPTVENVLGRGRVTIMSVSFVMSLWAGSSAMSCFVSSIVHAHG  126

Query  135  QTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPE----SLANLLRYGYY  190
            Q  +RHPV QR FAL +Y+V LV  V   P++ +GP  + E +P+    ++++L+ +GY+
Sbjct  127  QHEIRHPVWQRIFALLIYMVFLVSGVLVLPLVALGPTYLHEILPDAWDPAVSDLVDWGYF  186

Query  191  PALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTY  250
            P + + L   ++ LYR ALP P+P HRL+ GA+LA   F IAT  LR YL  +TR GYTY
Sbjct  187  PFVGVLLIGALVTLYRFALPYPMPWHRLLPGALLAGVFFWIATYVLRFYLTALTRAGYTY  246

Query  251  GALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKARIGVGTTTYS  310
            GALATPIAFLLF FF GFAI+LGAE+NA+++E WPA       + NW+ ++    TT  +
Sbjct  247  GALATPIAFLLFTFFLGFAIVLGAEMNASIEELWPARGG-GGVVRNWVTSQ----TTELT  301

Query  311  STAQHSAVAAE  321
             T ++ A+   
Sbjct  302  DTLRNRALNGR  312


>gi|262202174|ref|YP_003273382.1| ribonuclease BN [Gordonia bronchialis DSM 43247]
 gi|262085521|gb|ACY21489.1| ribonuclease BN [Gordonia bronchialis DSM 43247]
Length=426

 Score =  221 bits (563),  Expect = 1e-55, Method: Compositional matrix adjust.
 Identities = 149/291 (52%), Positives = 198/291 (69%), Gaps = 4/291 (1%)

Query  15   RITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSA  74
            R+  RT   +WD  I   SAQAAFW ALSLPPLLLG+LGS+ Y+A  FGPDT+  I +  
Sbjct  98   RLAWRTTVNAWDHGIVGWSAQAAFWQALSLPPLLLGLLGSVGYIAGWFGPDTVDVIYERI  157

Query  75   LSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHD  134
            +S A   FS SVVN++I PT+ ++ N  R  + SLGF++SLWAGSSA+S F+ ++V AHD
Sbjct  158  ISFADRTFSESVVNDLITPTVDNVLNRGRVGLVSLGFVLSLWAGSSAVSCFISSIVHAHD  217

Query  135  QTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES----LANLLRYGYY  190
            Q  +R+PV QR FAL LY+  L   V   P++ +GP  + + +P+S    +  L+  GY+
Sbjct  218  QHEVRNPVWQRIFALLLYIGFLCAAVPLLPLVALGPNYLHDIVPQSWDPIITTLIDVGYF  277

Query  191  PALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTY  250
            P + + L   +  LY +ALP PLP HRL+ GAVLA  VF IA+  LR+YL  +TR  Y+Y
Sbjct  278  PFVSVLLLGVLTTLYHLALPNPLPWHRLMGGAVLAGMVFWIASYILRIYLTAVTRADYSY  337

Query  251  GALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLKAR  301
            GALATPIAFLLFAFF GFAI+LGAE NAAVQ  WPA A+   ++  W+ ++
Sbjct  338  GALATPIAFLLFAFFLGFAIVLGAEFNAAVQALWPAKASATTQVREWVNSQ  388


>gi|284989615|ref|YP_003408169.1| ribonuclease BN [Geodermatophilus obscurus DSM 43160]
 gi|284062860|gb|ADB73798.1| ribonuclease BN [Geodermatophilus obscurus DSM 43160]
Length=355

 Score =  219 bits (558),  Expect = 5e-55, Method: Compositional matrix adjust.
 Identities = 137/286 (48%), Positives = 190/286 (67%), Gaps = 4/286 (1%)

Query  6    PKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPD  65
            P   R    R+ RRT+  +W+D IF+ESA AAFW  LSLPPLLLG+ G L YV   FGPD
Sbjct  20   PASRRSAAHRLVRRTMGNAWNDDIFTESAAAAFWQTLSLPPLLLGLFGILGYVGGAFGPD  79

Query  66   TLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAF  125
            T+ A+++  +      FS + ++EII PT+ D+ + AR EV S+GF++S W+GSSA+++F
Sbjct  80   TIAAVQQWIIDLTGGVFSRNALDEIIAPTVADVLSTARAEVISVGFVLSFWSGSSAMASF  139

Query  126  VDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPE----SL  181
            VDA+  AHDQ  +R+ + QR  ++ +Y+V LV  +   P++ +GP +V   +P+    S 
Sbjct  140  VDAITRAHDQYEVRNLIWQRTLSMLMYLVGLVTGILVLPLLALGPERVLPLLPDSWQHSA  199

Query  182  ANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLA  241
               +   YYP L L L + +  LYRVALP+  P +R + GA+LA  VFL  + GLR+YL 
Sbjct  200  GTAVDTVYYPVLGLVLLLALTTLYRVALPLKPPWYRGLPGALLAALVFLAGSSGLRLYLD  259

Query  242  WITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAP  287
            W+T +GYTYGALA PIAFLL  FF  FAI+LGA+LNAA+Q  WP P
Sbjct  260  WLTGSGYTYGALAAPIAFLLATFFIAFAIILGAQLNAAIQALWPVP  305


>gi|331696938|ref|YP_004333177.1| ribonuclease BN [Pseudonocardia dioxanivorans CB1190]
 gi|326951627|gb|AEA25324.1| ribonuclease BN [Pseudonocardia dioxanivorans CB1190]
Length=409

 Score =  218 bits (555),  Expect = 1e-54, Method: Compositional matrix adjust.
 Identities = 144/288 (50%), Positives = 190/288 (66%), Gaps = 5/288 (1%)

Query  3    DQVPKPHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLF  62
            ++ P P R    ++  RT+  +WDD+IFSESA AAFW  LSLPPLLLG+LGSL Y+   F
Sbjct  100  NEEPAPKRGAK-QLAVRTIVGAWDDNIFSESASAAFWQTLSLPPLLLGLLGSLGYIGEWF  158

Query  63   GPDTLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAI  122
            GP+T   +E   ++     F+   V++II PT+  I    R E+ SLGF+ISLW+GSSA+
Sbjct  159  GPNTAQIVEARIIAATSGIFTRDAVDQIIAPTVSQILTTGRSELVSLGFVISLWSGSSAM  218

Query  123  SAFVDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLA  182
            S+FVDA+  AH Q  +R+PV QR  AL LYVV LV  + + P++ +GP ++   +PES  
Sbjct  219  SSFVDAITRAHGQYGIRNPVWQRILALLLYVVALVGGIISLPLLALGPDRLPGILPESWR  278

Query  183  ----NLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRV  238
                 L+   YYP + + L + +  LY+VALP   P  R + GA+LA  VFL    GLRV
Sbjct  279  PAAITLIADLYYPVIGVILVLALTTLYKVALPAKPPWWRGLPGALLAAVVFLAGVTGLRV  338

Query  239  YLAWITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPA  286
            Y+ W+T TGYTYGALA PIAFLL AFF GFAI+LGA LNA++Q  WPA
Sbjct  339  YINWVTGTGYTYGALAAPIAFLLAAFFIGFAIVLGAHLNASIQALWPA  386


>gi|284991960|ref|YP_003410514.1| ribonuclease BN [Geodermatophilus obscurus DSM 43160]
 gi|284065205|gb|ADB76143.1| ribonuclease BN [Geodermatophilus obscurus DSM 43160]
Length=354

 Score =  198 bits (503),  Expect = 1e-48, Method: Compositional matrix adjust.
 Identities = 121/279 (44%), Positives = 174/279 (63%), Gaps = 4/279 (1%)

Query  19   RTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSALSTA  78
            RT++K+W D I   SA+AAFW  LS+PPLL+G+LG+L Y+    G  ++  IE   +  +
Sbjct  58   RTVAKAWHDRILGLSAEAAFWQILSVPPLLIGLLGTLGYLGTFIGDASVARIEAELVRAS  117

Query  79   HSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQTPL  138
                +P VV  +++PT+ DI  + R ++ S+GFL+SLWAGSSA + F++ VV A+DQ  +
Sbjct  118  TEVLTPDVVEGLVQPTLDDILGSGRLDLVSVGFLLSLWAGSSATATFMNTVVIAYDQRDV  177

Query  139  RHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLAN----LLRYGYYPALI  194
            R P+R R  AL+L+VV L+  V T P++V+G   +   +P         L+   Y+P ++
Sbjct  178  RGPIRTRLKALWLFVVGLLLAVVTLPLLVLGRGVLVSLLPADWRGTATVLVNAVYWPVVL  237

Query  195  LGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTYGALA  254
            +GL + +   Y V LP  LP HR + G VLA+A F++  L  R Y+A I  T   YGALA
Sbjct  238  VGLLLALTSFYHVVLPRRLPWHRHLPGTVLAVAFFVVTALATRTYVADILTTTLPYGALA  297

Query  255  TPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHR  293
            TPIA LLF FF G +++LGAELNA +Q  WPAP     R
Sbjct  298  TPIAVLLFCFFFGMSVLLGAELNATIQARWPAPLRRHQR  336


>gi|258653906|ref|YP_003203062.1| ribonuclease BN [Nakamurella multipartita DSM 44233]
 gi|258557131|gb|ACV80073.1| ribonuclease BN [Nakamurella multipartita DSM 44233]
Length=356

 Score =  191 bits (484),  Expect = 2e-46, Method: Compositional matrix adjust.
 Identities = 125/298 (42%), Positives = 185/298 (63%), Gaps = 7/298 (2%)

Query  8    PHRHHIWR-ITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGP-D  65
            P   H WR +  RTLSK+W DS+F  S+QAAFW ALS  PLLL +LG + YV   + P  
Sbjct  40   PRVRHRWRKVIGRTLSKAWGDSLFGMSSQAAFWCALSTAPLLLALLGLVGYVVGWYFPAG  99

Query  66   TLPAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAF  125
            T+  + +  L   ++ F+  V + ++  T+  I +  + +V S+G +ISLWAGSSA+SAF
Sbjct  100  TIDQVREQILIFLNAIFNEEVADNLVGNTVETILSQGQADVVSVGLVISLWAGSSAMSAF  159

Query  126  VDAVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES----L  181
            V+++  A+ Q  +RHPV +RFFAL LY++ L+  +   P++ +GP  + +  PES    +
Sbjct  160  VESITIAYGQHEVRHPVAERFFALGLYLLALLSGIIMLPLLAIGPDYLPKVFPESWRPQV  219

Query  182  ANLLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLA  241
            +N++   YYP L LGL   + +LY+VA     P +R V GA LA AVF++ + GLR+YL+
Sbjct  220  SNIVNIAYYPTLALGLIFLLTVLYKVAPKHKHPWYRGVPGAFLAAAVFIVTSFGLRLYLS  279

Query  242  WITRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGNWLK  299
            ++   G TYGALATPI FLLF +F   A+++GA+ N A  E +P P      L  W +
Sbjct  280  YVYAHGLTYGALATPITFLLFYYFVSMAVIIGAQFNNATLEYYP-PRPSKRELRRWQR  336


>gi|258650769|ref|YP_003199925.1| ribonuclease BN [Nakamurella multipartita DSM 44233]
 gi|258553994|gb|ACV76936.1| ribonuclease BN [Nakamurella multipartita DSM 44233]
Length=298

 Score =  187 bits (475),  Expect = 2e-45, Method: Compositional matrix adjust.
 Identities = 124/283 (44%), Positives = 176/283 (63%), Gaps = 10/283 (3%)

Query  20   TLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSALSTAH  79
            TL+K+W DS+F  SAQAAFWSALS  PLLL +LG   YVA   GP+T   I +      H
Sbjct  19   TLAKAWGDSLFGMSAQAAFWSALSTAPLLLALLGLSGYVARAIGPNTTGEIREQVNVFLH  78

Query  80   SFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQTPLR  139
            + F+  V + +I  T+  I N+++ +V S+G +ISLWAGSSA++AFV+++  A+ Q   R
Sbjct  79   TIFNQEVADNLIGNTVDVILNSSQTDVVSVGLIISLWAGSSAMTAFVESIAIAYGQHEFR  138

Query  140  HPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIP----ESLANLLRYGYYPALIL  195
            HPV +RFFAL LYV  L   +   P++ +GP  +    P     +++ ++ + YYP L +
Sbjct  139  HPVLERFFALGLYVGALAAGIVMVPLLAIGPDYLPRLFPPDWRSAVSEIIGWLYYPGLAI  198

Query  196  GLTVGVILLYRVALPVPLPTHRLVL---GAVLAIAVFLIATLGLRVYLAWITRTGYTYGA  252
            GL + +  LY+VA   P   HR +    GA LA AVFL A+ GLR+YL+++   G TYGA
Sbjct  199  GLILLLTTLYKVA---PKDKHRWMRGLPGAFLAAAVFLTASTGLRLYLSYVYEHGLTYGA  255

Query  253  LATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLG  295
            LATPI FLLF +F   AI++GA+ N A+ E +P   +   R G
Sbjct  256  LATPITFLLFYYFISMAIIIGAQFNNALLEYYPPRTSRRQRRG  298


>gi|158313101|ref|YP_001505609.1| ribonuclease BN [Frankia sp. EAN1pec]
 gi|158108506|gb|ABW10703.1| ribonuclease BN [Frankia sp. EAN1pec]
Length=360

 Score =  177 bits (448),  Expect = 3e-42, Method: Compositional matrix adjust.
 Identities = 98/272 (37%), Positives = 159/272 (59%), Gaps = 4/272 (1%)

Query  15   RITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSA  74
            R+ R T++ +W   +   +A+A FW  LS+PPLLL +LG++ Y+  L G D L  +  S 
Sbjct  64   RLARTTVANAWRHRVLGLAAEAGFWQLLSMPPLLLALLGTIGYIGDLLGGDALDNVRLSI  123

Query  75   LSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHD  134
            L  A +  + SVV++ + PTI +I +  R +V S+GF++SLW GS+A++ FV+ +  A+ 
Sbjct  124  LDGADNLLTASVVDDTVRPTIDEILSRGRPDVISIGFVLSLWTGSTAMATFVNTITIAYG  183

Query  135  QTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES----LANLLRYGYY  190
            Q  LR  VR R  AL L++  +   V   P +V+GP  +S+ +       + +LL+  ++
Sbjct  184  QRELRSAVRSRLLALGLFLAQVATGVLLLPALVLGPGLLSDMLNSGRHPVVDDLLKILFW  243

Query  191  PALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTY  250
            P + +     +  LY +ALPV     R + GA LA+ ++L+ +  LR+YL  +      Y
Sbjct  244  PVVGVVSLAMLTTLYHLALPVRRSWRRALPGAALALFLWLVGSYLLRMYLELVFSNELVY  303

Query  251  GALATPIAFLLFAFFGGFAIMLGAELNAAVQE  282
            G+L  P+A LLF +    A++LGAELNAA+ E
Sbjct  304  GSLGAPVAALLFFYITALAVLLGAELNAAIDE  335


>gi|288920775|ref|ZP_06415075.1| ribonuclease BN [Frankia sp. EUN1f]
 gi|288347851|gb|EFC82128.1| ribonuclease BN [Frankia sp. EUN1f]
Length=367

 Score =  160 bits (404),  Expect = 3e-37, Method: Compositional matrix adjust.
 Identities = 101/277 (37%), Positives = 161/277 (59%), Gaps = 4/277 (1%)

Query  15   RITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSA  74
            R+ R T++ +W   +   +A+A FW  LS+PPLLL +LG++ Y+    G D +  + +S 
Sbjct  80   RLARATVANAWRHRVLGLAAEAGFWQLLSMPPLLLALLGAIGYLGDTLGGDAVDNVRQSI  139

Query  75   LSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHD  134
            L  A +  + SVV+  + PTI  I +  R +V S+GFL+SLW GS+A++ FV+ +  A+ 
Sbjct  140  LGGADNLLTASVVDGTVRPTIDQILSRGRPDVISIGFLLSLWTGSTAMATFVNTITIAYG  199

Query  135  QTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPE----SLANLLRYGYY  190
            Q  LR  VR R  AL+L++  +   V   P +V+GP  +S+ +      ++  LLR  ++
Sbjct  200  QRDLRSAVRSRLLALWLFMAQVATGVILLPALVLGPSLLSDLLDAGRHPAVDELLRDVFW  259

Query  191  PALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTY  250
            P + +     +  LY +ALP   P  R + GA LA+ ++L+ +  LR+YL  +      Y
Sbjct  260  PVVGVVALAMLTTLYHLALPQRRPWRRALPGAALALFLWLVGSYLLRMYLELVFSNELVY  319

Query  251  GALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAP  287
            G+LA P+A LLF +    A++LGAELNAA+ E  P P
Sbjct  320  GSLAAPVAALLFFYITALAVLLGAELNAALDERPPRP  356


>gi|86742177|ref|YP_482577.1| ribonuclease BN [Frankia sp. CcI3]
 gi|86569039|gb|ABD12848.1| ribonuclease BN [Frankia sp. CcI3]
Length=342

 Score =  159 bits (401),  Expect = 8e-37, Method: Compositional matrix adjust.
 Identities = 104/273 (39%), Positives = 160/273 (59%), Gaps = 8/273 (2%)

Query  19   RTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSALSTA  78
            RT++ +W   +   +A+A FW  LSLPPLLL +LG+L YV    G D L +  +S L  A
Sbjct  56   RTITNAWRHRVLGLAAEAGFWQLLSLPPLLLSLLGTLGYVGDAIGADALDSARQSILHGA  115

Query  79   HSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHDQTPL  138
                + SVV++ + PTI  I +  R +V S+GF++SLW GS+A++ FV+ +  A+ Q  L
Sbjct  116  GGLLTESVVDDAVRPTIDQILSRGRPDVISIGFVLSLWTGSTAMATFVNTITIAYGQREL  175

Query  139  RHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPES----LANLLRYGYYPALI  194
            R  VR R  AL+L++  +   V   P +V+GP  +S     S    ++ L+   Y+P  +
Sbjct  176  RSAVRSRLLALWLFLAQVASGVILLPALVLGPELISRIFDASRHPLVSTLITLLYWP--V  233

Query  195  LGLTVGVIL--LYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTYGA  252
            +GL    +L  LY ++LPV  P  R + GA+LA+  +L+ +  LR YL  +      YG+
Sbjct  234  VGLVALAMLTSLYHLSLPVRRPWWRALPGAILALVCWLVGSGVLRYYLEIVFSHELVYGS  293

Query  253  LATPIAFLLFAFFGGFAIMLGAELNAAVQEEWP  285
            L +P+A LLF +    A++LGAELNAA+ E+ P
Sbjct  294  LGSPVAALLFFYITALAVLLGAELNAALDEQPP  326


>gi|111225044|ref|YP_715838.1| hypothetical protein FRAAL5685 [Frankia alni ACN14a]
 gi|111152576|emb|CAJ64318.1| Conserved hypothetical protein; putative membrane protein [Frankia 
alni ACN14a]
Length=453

 Score =  157 bits (396),  Expect = 3e-36, Method: Compositional matrix adjust.
 Identities = 104/275 (38%), Positives = 161/275 (59%), Gaps = 8/275 (2%)

Query  15   RITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKSA  74
            R+ R TL+ +W   +   +A+A FW  LSLPPLLL +LG+L YVA   G D L +I  S 
Sbjct  86   RLARTTLANAWRHRVLGLAAEAGFWQLLSLPPLLLSLLGALGYVADAIGGDALSSIRDSI  145

Query  75   LSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAHD  134
            L  A    + SVV++ + PT+ +I +  R +V S+GF++SLW GS+A++ FV+ +  A+ 
Sbjct  146  LRGAGDLLTESVVDDAVRPTVDEILSRGRPDVISIGFVLSLWTGSTAMATFVNTITIAYG  205

Query  135  QTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPE----SLANLLRYGYY  190
            Q   R  VR R  AL L++  +   V   P +++GP  +S  +      S+ +LL   ++
Sbjct  206  QRDRRSAVRSRLVALGLFLAQVTSGVIILPALILGPGLISRILDADQHPSVDHLLTLLFW  265

Query  191  PALILGLTVGVIL--LYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGY  248
            P  ++GL    +L  LY ++LPV  P  R + GA LA+  +L+ +  LR+YL  +     
Sbjct  266  P--VVGLVALTMLTSLYHLSLPVRRPWWRALPGATLALVCWLVGSDVLRLYLEIVFSHEL  323

Query  249  TYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEE  283
             YG+L  P+A LLF +    A++LGAELNAA+ E+
Sbjct  324  VYGSLGAPVAALLFFYITALAVLLGAELNAALDEQ  358


>gi|302541789|ref|ZP_07294131.1| putative integral membrane protein [Streptomyces hygroscopicus 
ATCC 53653]
 gi|302459407|gb|EFL22500.1| putative integral membrane protein [Streptomyces himastatinicus 
ATCC 53653]
Length=390

 Score =  153 bits (386),  Expect = 4e-35, Method: Compositional matrix adjust.
 Identities = 108/313 (35%), Positives = 169/313 (54%), Gaps = 3/313 (0%)

Query  14   WRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKS  73
            W + + T++   +  +   +A+AAF++ LSLPPLLLG++G L Y       DT+  I ++
Sbjct  3    WLLLKDTVNSCMEYRVTGLAAEAAFFTLLSLPPLLLGLIGLLGYFDAWTDTDTVATIRQN  62

Query  74   ALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAH  133
             L  + +  S   V EI  P + D+    R +V SLGF I+LW+GS A++ FVD +   +
Sbjct  63   ILDASGTVLSDKGVKEIARPLLDDVIEGGRPDVISLGFGIALWSGSRAVNVFVDTITIMY  122

Query  134  DQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLANLLRYGYYPAL  193
                 R  VR R  A  LY+V LV      P+MV+GP  V + +P S A L+R  Y+P +
Sbjct  123  GLEGRRGIVRTRLLAFLLYLVALVIGAVALPLMVIGPETVVDFVPSS-ATLVRVLYWPTV  181

Query  194  ILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTYGAL  253
            IL     +  LY V++PV       + GA++A+ ++++ +  LR+YL         YG+L
Sbjct  182  ILLSVAFLTTLYHVSVPVRSAWREDIPGALVALTMWVLGSFLLRIYLIHTVEGPTIYGSL  241

Query  254  ATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHRLGN--WLKARIGVGTTTYSS  311
            A P+A LL+     FA+++GA +NAA+   WP+ AT A R     W + +  +G      
Sbjct  242  AAPVAVLLWIGVSAFAVLVGAAVNAAIDRVWPSVATAAGRAQREAWTREQAALGRAREQR  301

Query  312  TAQHSAVAAEPPS  324
            TA   +  + PPS
Sbjct  302  TADDGSAESTPPS  314


>gi|320007739|gb|ADW02589.1| ribonuclease BN [Streptomyces flavogriseus ATCC 33331]
Length=350

 Score =  153 bits (386),  Expect = 5e-35, Method: Compositional matrix adjust.
 Identities = 105/280 (38%), Positives = 162/280 (58%), Gaps = 1/280 (0%)

Query  14   WRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLPAIEKS  73
            W++ + T++   +  I   +A+AAF++ LSLPPLLLG++G L YV       T+ +IE++
Sbjct  3    WQLLKDTVNSCIEYRILGLAAEAAFFTLLSLPPLLLGLIGLLGYVDDWTSTTTVASIERN  62

Query  74   ALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDAVVEAH  133
             L    +  S   VN+I +P I D+T  AR +V SLGF I+LW+GS A++ F+D +   +
Sbjct  63   ILGAVQTVLSERGVNDIAKPLIADVTTGARPDVISLGFAIALWSGSRAVNVFIDTITVMY  122

Query  134  DQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLANLLRYGYYPAL  193
                 R  V+ R  A  LYVV L+      P++VVGP +V E +P     +L   Y+P +
Sbjct  123  GLDGHRGIVKTRLLAFLLYVVALLLGAVVLPLLVVGPDRVVEFVPWG-TEVLAVMYWPLV  181

Query  194  ILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGYTYGAL  253
            IL     +  LY V++PV  P    V GA++A+ ++++ +  LR+YL         YG+L
Sbjct  182  ILLSIAFLTTLYHVSVPVRSPWIEDVPGALVALGMWVLGSFLLRIYLTSTVEGPTIYGSL  241

Query  254  ATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHR  293
            A PIA LL+     FA+++GA +NAA+   WP+ AT A R
Sbjct  242  AAPIAVLLWIGISAFAVLVGAAVNAAIDRVWPSLATAAAR  281


>gi|297191204|ref|ZP_06908602.1| integral membrane protein [Streptomyces pristinaespiralis ATCC 
25486]
 gi|297150821|gb|EDY62426.2| integral membrane protein [Streptomyces pristinaespiralis ATCC 
25486]
Length=370

 Score =  152 bits (384),  Expect = 8e-35, Method: Compositional matrix adjust.
 Identities = 93/278 (34%), Positives = 159/278 (58%), Gaps = 1/278 (0%)

Query  9    HRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLP  68
             R  +W + + T++   +  I   +A+AAF++ LS+PPL+LG++G L Y+       T+ 
Sbjct  27   KRKMVWLLLKDTVNSCIEYRILGLAAEAAFFTLLSVPPLMLGLIGLLGYIDDWTNTTTVA  86

Query  69   AIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDA  128
            +IE++ L+   +  S   VN+I +P + D+T   R ++ S+GF I+LW+GS A++ F+D 
Sbjct  87   SIEENILTAVGTVLSDRGVNDIAKPLLEDVTQGGRPDLISIGFAIALWSGSRAVNVFIDT  146

Query  129  VVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLANLLRYG  188
            +   +     R  V  R  A  LY+V L+      P+ VVGP +V E +P     ++R  
Sbjct  147  ITVMYGLDGHRGIVATRLLAFLLYIVALLIGAVVLPLAVVGPDRVVELMPWG-TEVVRIL  205

Query  189  YYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGY  248
            Y+P ++L     +  LY V++PV  P    + GA++A+ ++++ +  LR+YL        
Sbjct  206  YWPVVMLLSIAFLTTLYHVSVPVRSPWVEDIPGALVALGMWILGSFLLRIYLTSQVEGPT  265

Query  249  TYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPA  286
             YG+LA PIAFLL+     FA+++GA +NAA+   WP+
Sbjct  266  IYGSLAAPIAFLLWIGISAFAVLVGAAVNAAIDRVWPS  303


>gi|345002845|ref|YP_004805699.1| ribonuclease BN [Streptomyces sp. SirexAA-E]
 gi|344318471|gb|AEN13159.1| ribonuclease BN [Streptomyces sp. SirexAA-E]
Length=399

 Score =  152 bits (383),  Expect = 1e-34, Method: Compositional matrix adjust.
 Identities = 103/278 (38%), Positives = 161/278 (58%), Gaps = 1/278 (0%)

Query  9    HRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLP  68
             R   WR+ + T++   +  I   +A+AAF++ LSLPPLLLG++G L YV       T+ 
Sbjct  27   KRQMAWRLIKDTVNSCMEYRILGLAAEAAFFTLLSLPPLLLGLIGLLGYVDEWTSTTTVA  86

Query  69   AIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDA  128
            +IE++ LS   +  S   VN+I +P + D+T  AR +V S+GF I+LW+GS A++ F++ 
Sbjct  87   SIERNILSAVQTVLSERGVNDIAKPLLEDVTTGARPDVISIGFAIALWSGSRAVNVFIET  146

Query  129  VVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLANLLRYG  188
            +   +     R  V+ R  A  LYVV LV      P++VVGP +V E +P     LL   
Sbjct  147  ITVMYGLDGHRGIVKTRLLAFLLYVVALVLGSVVLPLLVVGPDRVVEFVPWG-TELLAVL  205

Query  189  YYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGY  248
            Y+P +I+     +  LY V++PV  P    V GA++A+A++++ +  LR+YL        
Sbjct  206  YWPLVIVLSIAFLTTLYHVSVPVRSPWMEDVPGALVALAMWVLGSFLLRIYLTSTVEGPT  265

Query  249  TYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPA  286
             YG+LA PIA LL+     FA+++GA +NAA+   WP+
Sbjct  266  IYGSLAAPIAVLLWIGISAFAVLVGAAVNAAIDRVWPS  303


>gi|312195054|ref|YP_004015115.1| ribonuclease BN [Frankia sp. EuI1c]
 gi|311226390|gb|ADP79245.1| ribonuclease BN [Frankia sp. EuI1c]
Length=452

 Score =  150 bits (379),  Expect = 2e-34, Method: Compositional matrix adjust.
 Identities = 106/289 (37%), Positives = 165/289 (58%), Gaps = 7/289 (2%)

Query  9    HRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLP  68
            H     R+  R +S +W D +   +A+A FW  LSLPPLLL +LGS+ Y+    G D + 
Sbjct  126  HAADAGRVAARAMSNAWRDRVLGLAAEAGFWQLLSLPPLLLALLGSIGYLGDALGSDAVN  185

Query  69   AIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDA  128
            +I  S L  A    +  VV++++ PT+  I  + R +V S+GF++SLW GS+A++ FV+ 
Sbjct  186  SIRNSLLRGADDLLTADVVDDVVRPTVDQILTHGRPDVISIGFVLSLWTGSTAMATFVNT  245

Query  129  VVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSE-----HIPESLAN  183
            +  A+ Q  LR  VR R  AL L+++ ++  +   P +V+GP  ++E     H P ++  
Sbjct  246  ITIAYGQRDLRSAVRSRIVALRLFIIQVITGIILLPALVLGPGLLAELLRAKHHP-TIEL  304

Query  184  LLRYGYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWI  243
            LL+  ++P + +     +  LY  ALP   P  R + GAV A+  +L+ +  LR+YL  +
Sbjct  305  LLKSAFWPVVAVVALTVLTSLYHQALPQRRPWRRALPGAVFALVGWLVGSYVLRLYLERV  364

Query  244  TRTGYTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWP-APATHA  291
                  YG+LA P A LLF +  G A++LGAELNAA+ +  P APA  A
Sbjct  365  FGNELVYGSLAAPAAALLFFYITGLAVLLGAELNAALDQRRPGAPAPEA  413


>gi|328885970|emb|CCA59209.1| putative integral membrane protein [Streptomyces venezuelae ATCC 
10712]
Length=374

 Score =  149 bits (377),  Expect = 4e-34, Method: Compositional matrix adjust.
 Identities = 101/281 (36%), Positives = 159/281 (57%), Gaps = 1/281 (0%)

Query  9    HRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTLP  68
             R  +W + + T++   +  I   +A+AAF++ LSLPPLLLG++  L Y       DT+ 
Sbjct  31   KRKMVWLLLKDTVNSCIEYRILGLAAEAAFFTLLSLPPLLLGLIAVLGYADDWTNTDTVA  90

Query  69   AIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVDA  128
            +I ++ L  A +  S   V EI EP + DIT   R ++ SLGF I+LW+GS A++ F+D 
Sbjct  91   SIRENILHAAGTVLSDRGVREIAEPLLDDITQGKRPDLISLGFAIALWSGSRAVNVFIDT  150

Query  129  VVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLANLLRYG  188
            +   +     R  V+ R  AL LY+V L+      P+ VVGP +V E +P     ++   
Sbjct  151  ITVMYGLDGHRGIVKTRLLALLLYIVALLIGAIVLPLAVVGPDRVVELVPWG-TEVVSVL  209

Query  189  YYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTGY  248
            Y+PA+IL     +  LY V++PV  P    + GA++A+ ++++ +  LR+YL        
Sbjct  210  YWPAVILLSIAFLTTLYHVSVPVRSPWIEDIPGALVALGMWVLGSFLLRIYLTSQVEGPT  269

Query  249  TYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPAT  289
             YG+LA PIA LL+     FA+++GA +NAA+   WP+ AT
Sbjct  270  IYGSLAAPIAVLLWIGISAFAVLVGAAVNAAIDRVWPSVAT  310


>gi|84496269|ref|ZP_00995123.1| putative integral membrane protein [Janibacter sp. HTCC2649]
 gi|84383037|gb|EAP98918.1| putative integral membrane protein [Janibacter sp. HTCC2649]
Length=381

 Score =  149 bits (377),  Expect = 5e-34, Method: Compositional matrix adjust.
 Identities = 85/286 (30%), Positives = 156/286 (55%), Gaps = 1/286 (0%)

Query  8    PHRHHIWRITRRTLSKSWDDSIFSESAQAAFWSALSLPPLLLGMLGSLAYVAPLFGPDTL  67
            P    + R+T  T+       +   +++A F++ LSLPPL+LG+ G + Y+    G DT+
Sbjct  16   PALESLARLTVETIRICLRYRVTGLASEAGFFALLSLPPLVLGLFGGVGYIGRWLGQDTV  75

Query  68   PAIEKSALSTAHSFFSPSVVNEIIEPTIGDITNNARGEVASLGFLISLWAGSSAISAFVD  127
              + ++    A  F +  V++  + PT+ D+    R ++ S+GF++SLW+GS A++  VD
Sbjct  76   ATVREAITEYAARFLTDDVISSTLAPTVDDVFTAGRFDLISVGFVLSLWSGSRALNVLVD  135

Query  128  AVVEAHDQTPLRHPVRQRFFALFLYVVMLVFLVATAPVMVVGPRKVSEHIPESLANLLRY  187
             V   + Q+ +R  V  R  +  LY+V LV  + T P++++GP  + E +P++  + L +
Sbjct  136  TVSIMYGQSGVRGIVPTRVLSFSLYIVALVVGIITIPLVLIGPTLLGEVLPDTW-DFLTF  194

Query  188  GYYPALILGLTVGVILLYRVALPVPLPTHRLVLGAVLAIAVFLIATLGLRVYLAWITRTG  247
             Y+P + L +      LY V+ P+  P  R + GAVL + ++++A+  +R  +A      
Sbjct  195  LYWPVVSLVVIAAFTSLYHVSTPLRSPWTRDIPGAVLTLLIWVVASFAVRGSIAASLGGT  254

Query  248  YTYGALATPIAFLLFAFFGGFAIMLGAELNAAVQEEWPAPATHAHR  293
              YG L+ PI  L++ +    A+++GA LNA ++  WP+      R
Sbjct  255  SIYGPLSAPIVLLIWLYMLAIAVLIGAALNAGIRNLWPSGEQRGLR  300



Lambda     K      H
   0.324    0.137    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 574046524410


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40