BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2756c Length=540 Score E Sequences producing significant alignments: (Bits) Value gi|15609893|ref|NP_217272.1| type I restriction/modification sys... 1115 0.0 gi|308378090|ref|ZP_07668665.1| putative type I restriction-modi... 1114 0.0 gi|15842294|ref|NP_337331.1| type I restriction system adenine m... 1112 0.0 gi|289448412|ref|ZP_06438156.1| type I restriction/modification ... 1110 0.0 gi|289575453|ref|ZP_06455680.1| type I restriction/modification ... 1110 0.0 gi|339632768|ref|YP_004724410.1| type I restriction/modification... 1107 0.0 gi|120401062|ref|YP_950891.1| N-6 DNA methylase [Mycobacterium v... 995 0.0 gi|339295608|gb|AEJ47719.1| type I restriction system adenine me... 971 0.0 gi|302528797|ref|ZP_07281139.1| type I restriction-modification ... 947 0.0 gi|240171167|ref|ZP_04749826.1| putative type I restriction/modi... 815 0.0 gi|258651342|ref|YP_003200498.1| adenine-specific DNA-methyltran... 800 0.0 gi|25028883|ref|NP_738937.1| putative type I restriction-modific... 789 0.0 gi|260905625|ref|ZP_05913947.1| N-6 DNA methylase [Brevibacteriu... 786 0.0 gi|220911869|ref|YP_002487178.1| N-6 DNA methylase [Arthrobacter... 784 0.0 gi|229822392|ref|YP_002883918.1| N-6 DNA methylase [Beutenbergia... 781 0.0 gi|259507945|ref|ZP_05750845.1| type I restriction-modification ... 778 0.0 gi|319951306|ref|ZP_08025140.1| putative type I restriction/modi... 758 0.0 gi|183981973|ref|YP_001850264.1| type I restriction/modification... 726 0.0 gi|334336398|ref|YP_004541550.1| Site-specific DNA-methyltransfe... 714 0.0 gi|227505724|ref|ZP_03935773.1| adenine-specific DNA-methyltrans... 712 0.0 gi|38234849|ref|NP_940616.1| putative type I restriction/modific... 708 0.0 gi|296270473|ref|YP_003653105.1| site-specific DNA-methyltransfe... 692 0.0 gi|172039827|ref|YP_001799541.1| type I restriction-modification... 685 0.0 gi|342858378|ref|ZP_08715033.1| type I restriction/modification ... 660 0.0 gi|271968782|ref|YP_003342978.1| Site-specific DNA-methyltransfe... 660 0.0 gi|296171676|ref|ZP_06852890.1| type I modification enzyme [Myco... 657 0.0 gi|297562021|ref|YP_003680995.1| adenine-specific DNA-methyltran... 628 1e-177 gi|307150615|ref|YP_003885999.1| adenine-specific DNA-methyltran... 556 4e-156 gi|87300611|ref|ZP_01083453.1| type I restriction system adenine... 555 7e-156 gi|253577074|ref|ZP_04854396.1| type I restriction-modification ... 554 1e-155 gi|291288454|ref|YP_003505270.1| adenine-specific DNA-methyltran... 554 2e-155 gi|256833459|ref|YP_003162186.1| N-6 DNA methylase [Jonesia deni... 553 3e-155 gi|253576200|ref|ZP_04853531.1| type I restriction-modification ... 550 2e-154 gi|71275992|ref|ZP_00652274.1| N-6 DNA methylase:Type I restrict... 548 1e-153 gi|88604024|ref|YP_504202.1| N-6 DNA methylase [Methanospirillum... 547 2e-153 gi|205372127|ref|ZP_03224943.1| type I restriction-modification ... 543 2e-152 gi|87310398|ref|ZP_01092528.1| type I restriction system adenine... 543 3e-152 gi|334702404|ref|ZP_08518270.1| type I restriction system adenin... 543 4e-152 gi|206603733|gb|EDZ40213.1| N-6 DNA methylase [Leptospirillum sp... 543 4e-152 gi|15839331|ref|NP_300019.1| type I restriction-modification sys... 542 6e-152 gi|251771139|gb|EES51722.1| N-6 DNA methylase [Leptospirillum fe... 541 8e-152 gi|94986116|ref|YP_605480.1| N-6 DNA methylase [Deinococcus geot... 540 2e-151 gi|251772354|gb|EES52922.1| N-6 DNA methylase [Leptospirillum fe... 539 4e-151 gi|291296826|ref|YP_003508224.1| Site-specific DNA-methyltransfe... 539 4e-151 gi|121609950|ref|YP_997757.1| N-6 DNA methylase [Verminephrobact... 538 7e-151 gi|198284500|ref|YP_002220821.1| N-6 DNA methylase [Acidithiobac... 537 2e-150 gi|83720663|ref|YP_443257.1| type I restriction system adenine m... 536 3e-150 gi|114330559|ref|YP_746781.1| N-6 DNA methylase [Nitrosomonas eu... 535 1e-149 gi|167847545|ref|ZP_02473053.1| N-6 DNA methylase [Burkholderia ... 534 1e-149 gi|302878446|ref|YP_003847010.1| Site-specific DNA-methyltransfe... 534 2e-149 >gi|15609893|ref|NP_217272.1| type I restriction/modification system DNA methylase HsdM [Mycobacterium tuberculosis H37Rv] gi|148662598|ref|YP_001284121.1| putative type I restriction/modification system DNA methylase HsdM [Mycobacterium tuberculosis H37Ra] gi|148823944|ref|YP_001288698.1| type I restriction/modification system DNA methylase hsdM [Mycobacterium tuberculosis F11] 38 more sequence titles Length=540 Score = 1115 bits (2884), Expect = 0.0, Method: Compositional matrix adjust. Identities = 540/540 (100%), Positives = 540/540 (100%), Gaps = 0/540 (0%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE Sbjct 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN Sbjct 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL Sbjct 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK Sbjct 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD Sbjct 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 Query 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS Sbjct 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 Query 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV Sbjct 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 Query 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA Sbjct 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 Query 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR Sbjct 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 >gi|308378090|ref|ZP_07668665.1| putative type I restriction-modification system, M subunit [Mycobacterium tuberculosis SUMu009] gi|308353571|gb|EFP42422.1| putative type I restriction-modification system, M subunit [Mycobacterium tuberculosis SUMu009] Length=718 Score = 1114 bits (2881), Expect = 0.0, Method: Compositional matrix adjust. Identities = 540/540 (100%), Positives = 540/540 (100%), Gaps = 0/540 (0%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE Sbjct 179 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 238 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN Sbjct 239 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 298 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL Sbjct 299 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 358 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK Sbjct 359 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 418 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD Sbjct 419 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 478 Query 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS Sbjct 479 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 538 Query 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV Sbjct 539 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 598 Query 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA Sbjct 599 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 658 Query 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR Sbjct 659 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 718 >gi|15842294|ref|NP_337331.1| type I restriction system adenine methylase [Mycobacterium tuberculosis CDC1551] gi|31793930|ref|NP_856423.1| type I restriction/modification system DNA methylase HsdM [Mycobacterium bovis AF2122/97] gi|121638634|ref|YP_978858.1| putative type I restriction/modification system DNA methylase hsdM [Mycobacterium bovis BCG str. Pasteur 1173P2] 30 more sequence titles Length=540 Score = 1112 bits (2875), Expect = 0.0, Method: Compositional matrix adjust. Identities = 539/540 (99%), Positives = 539/540 (99%), Gaps = 0/540 (0%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE Sbjct 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN Sbjct 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL Sbjct 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK Sbjct 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD Sbjct 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 Query 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 YVMAN PFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS Sbjct 301 YVMANPPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 Query 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV Sbjct 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 Query 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA Sbjct 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 Query 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR Sbjct 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 >gi|289448412|ref|ZP_06438156.1| type I restriction/modification system DNA methylase hsdM [Mycobacterium tuberculosis CPHL_A] gi|289421370|gb|EFD18571.1| type I restriction/modification system DNA methylase hsdM [Mycobacterium tuberculosis CPHL_A] Length=540 Score = 1110 bits (2872), Expect = 0.0, Method: Compositional matrix adjust. Identities = 538/540 (99%), Positives = 539/540 (99%), Gaps = 0/540 (0%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE Sbjct 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN Sbjct 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL Sbjct 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK Sbjct 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD Sbjct 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 Query 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 YVMAN PFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS Sbjct 301 YVMANPPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 Query 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV Sbjct 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 Query 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 LFIDARELGDLVDRA+RALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA Sbjct 421 LFIDARELGDLVDRAKRALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 Query 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR Sbjct 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 >gi|289575453|ref|ZP_06455680.1| type I restriction/modification system DNA methylase hsdM [Mycobacterium tuberculosis K85] gi|289539884|gb|EFD44462.1| type I restriction/modification system DNA methylase hsdM [Mycobacterium tuberculosis K85] Length=540 Score = 1110 bits (2870), Expect = 0.0, Method: Compositional matrix adjust. Identities = 538/540 (99%), Positives = 538/540 (99%), Gaps = 0/540 (0%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE Sbjct 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN Sbjct 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL Sbjct 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK Sbjct 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD Sbjct 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 Query 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 YVMAN PFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS Sbjct 301 YVMANPPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 Query 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV Sbjct 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 Query 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGS SAAVKGIMYEDVPGFCKSATLA Sbjct 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSNSAAVKGIMYEDVPGFCKSATLA 480 Query 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR Sbjct 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 >gi|339632768|ref|YP_004724410.1| type I restriction/modification system DNA methylase HSDM (M protein) [Mycobacterium africanum GM041182] gi|339332124|emb|CCC27831.1| putative type I restriction/modification system DNA methylase HSDM (M protein) [Mycobacterium africanum GM041182] Length=540 Score = 1107 bits (2863), Expect = 0.0, Method: Compositional matrix adjust. Identities = 537/540 (99%), Positives = 537/540 (99%), Gaps = 0/540 (0%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE Sbjct 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN Sbjct 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL Sbjct 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK Sbjct 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD Sbjct 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 Query 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 YVMAN PFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS Sbjct 301 YVMANPPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 Query 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV Sbjct 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 Query 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGS SAAVKGIMYEDVPGFCKSATLA Sbjct 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSNSAAVKGIMYEDVPGFCKSATLA 480 Query 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 IKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR Sbjct 481 AIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 >gi|120401062|ref|YP_950891.1| N-6 DNA methylase [Mycobacterium vanbaalenii PYR-1] gi|119953880|gb|ABM10885.1| N-6 DNA methylase [Mycobacterium vanbaalenii PYR-1] Length=544 Score = 995 bits (2573), Expect = 0.0, Method: Compositional matrix adjust. Identities = 478/542 (89%), Positives = 506/542 (94%), Gaps = 3/542 (0%) Query 1 MPPR---KKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDE 57 MPPR KK P PSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDE Sbjct 1 MPPRRGTKKAEPLLPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDE 60 Query 58 RREAIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEP 117 RREAIR EL A+G++ QIEDLI+DPE+YQGYGVFVVP ARWKFLAEN KG PA GGEP Sbjct 61 RREAIRTELEADGLDAEQIEDLIEDPEEYQGYGVFVVPPGARWKFLAENAKGLPAAGGEP 120 Query 118 AKNIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRA 177 AKNIGQLIDEAMDAVMKANPTL GTLPRLYNKDNIDQRRLGELIDLFNSARFSRQG+ RA Sbjct 121 AKNIGQLIDEAMDAVMKANPTLQGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGDGRA 180 Query 178 RDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQ 237 RDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPS GRVYDPCCGSGGMFVQ Sbjct 181 RDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSRGRVYDPCCGSGGMFVQ 240 Query 238 TEKFIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDV 297 TEKFIYEHDGDPK++++YGQESIEETWRMAKMNLAIHGIDNKGLGARW DTFARDQHPDV Sbjct 241 TEKFIYEHDGDPKEIAVYGQESIEETWRMAKMNLAIHGIDNKGLGARWGDTFARDQHPDV 300 Query 298 QMDYVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANG 357 QMDYV+AN PFNIKDWARNEED RWRFGVPPANNANYAWIQHILYKLA GG+AGVVMANG Sbjct 301 QMDYVLANPPFNIKDWARNEEDARWRFGVPPANNANYAWIQHILYKLASGGKAGVVMANG 360 Query 358 SMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRC 417 SMSSNSNGEGDIRAQIVEADLVSCM+ALPTQLFRSTGIPVC+WFFAKDK AGKQGS+DR Sbjct 361 SMSSNSNGEGDIRAQIVEADLVSCMIALPTQLFRSTGIPVCVWFFAKDKTAGKQGSVDRS 420 Query 418 GQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSA 477 GQVLFIDARE+G +VDRAERAL++++IV+IGDTFHAWRGS SAA KG++Y+DVPGFCKSA Sbjct 421 GQVLFIDAREMGYMVDRAERALSDDDIVKIGDTFHAWRGSASAAAKGVVYQDVPGFCKSA 480 Query 478 TLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLG 537 TLAEIKA DYALTPGRYVG AVEDDGEPIDEK+ARL LL AFDESARLE+VVREQL Sbjct 481 TLAEIKAADYALTPGRYVGAAAVEDDGEPIDEKIARLKTELLAAFDESARLEKVVREQLE 540 Query 538 RL 539 R+ Sbjct 541 RI 542 >gi|339295608|gb|AEJ47719.1| type I restriction system adenine methylase [Mycobacterium tuberculosis CCDC5079] Length=470 Score = 971 bits (2511), Expect = 0.0, Method: Compositional matrix adjust. Identities = 469/470 (99%), Positives = 469/470 (99%), Gaps = 0/470 (0%) Query 71 MEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMD 130 MEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMD Sbjct 1 MEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMD 60 Query 131 AVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLG 190 AVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLG Sbjct 61 AVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLG 120 Query 191 NFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPK 250 NFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPK Sbjct 121 NFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPK 180 Query 251 DVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNI 310 DVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMAN PFNI Sbjct 181 DVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANPPFNI 240 Query 311 KDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIR 370 KDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIR Sbjct 241 KDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIR 300 Query 371 AQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGD 430 AQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGD Sbjct 301 AQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGD 360 Query 431 LVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALT 490 LVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALT Sbjct 361 LVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALT 420 Query 491 PGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 PGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR Sbjct 421 PGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 470 >gi|302528797|ref|ZP_07281139.1| type I restriction-modification system, M subunit [Streptomyces sp. AA4] gi|302437692|gb|EFL09508.1| type I restriction-modification system, M subunit [Streptomyces sp. AA4] Length=541 Score = 947 bits (2448), Expect = 0.0, Method: Compositional matrix adjust. Identities = 451/539 (84%), Positives = 488/539 (91%), Gaps = 0/539 (0%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MPPRKK+ P APSTMKELKDTLWKAAD+LRGSLSA+QYKDVILGLVFLKYVSDAYDERRE Sbjct 1 MPPRKKKEPSAPSTMKELKDTLWKAADRLRGSLSANQYKDVILGLVFLKYVSDAYDERRE 60 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 AIRA+L AEG + QI DLIDDPE+YQGYGVFVVP +A+W +LA+ KGKPA G EPAKN Sbjct 61 AIRADLTAEGYDAEQIADLIDDPEEYQGYGVFVVPPTAQWDYLAQYAKGKPAEGTEPAKN 120 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IGQLIDEAMD VMK NP L GTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL Sbjct 121 IGQLIDEAMDLVMKTNPALQGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 MGEVYEYFLGNFAR+EGKRGGEFFTPPSVV+VIVEVLEPSSGRVYDPCCGSGGMFVQTEK Sbjct 181 MGEVYEYFLGNFARSEGKRGGEFFTPPSVVRVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 FIYEH+GDPKDVSI+GQES+EETWRMAKMNLAIHGI+NKGLGARW DTFARDQH D+QMD Sbjct 241 FIYEHNGDPKDVSIFGQESLEETWRMAKMNLAIHGIENKGLGARWGDTFARDQHADLQMD 300 Query 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 YVMAN PFNIK W+RN EDPRW+FGVPPA NANYAWIQHILYKLAPGG AGVVMANGSMS Sbjct 301 YVMANPPFNIKYWSRNTEDPRWKFGVPPATNANYAWIQHILYKLAPGGSAGVVMANGSMS 360 Query 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 SNSNGEG IRAQIVEADLVSCMVALPTQLFRSTGIPVC+WFFAKDK AGK G++DR GQV Sbjct 361 SNSNGEGAIRAQIVEADLVSCMVALPTQLFRSTGIPVCVWFFAKDKRAGKHGAVDRSGQV 420 Query 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 LFIDARELG +VDRAER L+NE+I +I DT+HAWRG++SAA K + Y DV GFCKS L Sbjct 421 LFIDARELGYMVDRAERTLSNEDIAKIADTYHAWRGTRSAAQKRLTYADVSGFCKSMGLP 480 Query 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 +IKA DYAL PGRYVG VEDDGEPID+K+ RL+ L+ AFD SA+LE+VVREQL RL Sbjct 481 DIKAVDYALDPGRYVGAAEVEDDGEPIDDKIQRLANELIAAFDASAQLEKVVREQLERL 539 >gi|240171167|ref|ZP_04749826.1| putative type I restriction/modification system DNA methylase [Mycobacterium kansasii ATCC 12478] Length=520 Score = 815 bits (2104), Expect = 0.0, Method: Compositional matrix adjust. Identities = 400/539 (75%), Positives = 442/539 (83%), Gaps = 21/539 (3%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MPP KKQ P ST+KEL+DTLWK+ADKLRGS+ ASQYKDVILGL+FLKY+SDA E+R Sbjct 1 MPPGKKQEP---STLKELQDTLWKSADKLRGSIGASQYKDVILGLLFLKYLSDADTEQRI 57 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 AI A L+A G + G F VP +ARW+ LA + +GK V GEPAK+ Sbjct 58 AIGATLSAGGTDR----------------GAFTVPPNARWELLAAHAEGKSVVAGEPAKS 101 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IG LID+AMDAVM+ANP L +LPR+YN+DNIDQRRLGEL+ LF++ARFSRQGEHRARDL Sbjct 102 IGALIDDAMDAVMQANPALAVSLPRMYNRDNIDQRRLGELVGLFSTARFSRQGEHRARDL 161 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 MGEVYEYF+GNFARAEGKRGGEFFTP SVVKVIVEVLEPS GRVYDPCCGSGGMFVQ EK Sbjct 162 MGEVYEYFVGNFARAEGKRGGEFFTPASVVKVIVEVLEPSRGRVYDPCCGSGGMFVQAEK 221 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 F YEH GD D+ IYGQES+EETWRMAKMNLA+HGIDNKGL RW DTF DQH V+MD Sbjct 222 FAYEHSGDVNDICIYGQESVEETWRMAKMNLAVHGIDNKGL--RWGDTFVCDQHAGVRMD 279 Query 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 YVMAN PFNIKDWAR+E+DPRWRFGVPPANNANYAWIQHIL KLAPGGRAGVVMANGSMS Sbjct 280 YVMANPPFNIKDWARDEKDPRWRFGVPPANNANYAWIQHILSKLAPGGRAGVVMANGSMS 339 Query 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 SNSNGEG IRA IV+ADLVSCMVALP QLFRSTGIPVCLWFFA DK AG QG+IDR GQV Sbjct 340 SNSNGEGIIRAHIVDADLVSCMVALPAQLFRSTGIPVCLWFFAMDKKAGCQGAIDRSGQV 399 Query 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 LFIDARE G LVDR ERAL EEI IGDT+HAWRG++SA K I Y+DV GFCKS LA Sbjct 400 LFIDAREFGHLVDRTERALAAEEITLIGDTYHAWRGTRSAGSKSIAYQDVCGFCKSVMLA 459 Query 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 EI+A +YALTPGRYV P E DGEPI + RL++ LL A DESARLE V+R+QL RL Sbjct 460 EIRAANYALTPGRYVDAPETECDGEPIGGDITRLTEDLLTALDESARLETVLRKQLKRL 518 >gi|258651342|ref|YP_003200498.1| adenine-specific DNA-methyltransferase [Nakamurella multipartita DSM 44233] gi|258554567|gb|ACV77509.1| Site-specific DNA-methyltransferase (adenine- specific) [Nakamurella multipartita DSM 44233] Length=548 Score = 800 bits (2067), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/549 (72%), Positives = 456/549 (84%), Gaps = 11/549 (2%) Query 1 MPPRKKQA----------PQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKY 50 MPPR ++A P A STMKELKDTLWKAADKLRGS+ ASQYKDVILGLVFLKY Sbjct 1 MPPRGRKASTAVTPAVSTPPAASTMKELKDTLWKAADKLRGSMDASQYKDVILGLVFLKY 60 Query 51 VSDAYDERREAIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGK 110 VSDA+DERRE IRAEL A+G++E QI+ +DD ++Y+G+GVF V ARW +LA++ KG Sbjct 61 VSDAFDERREQIRAELEADGIDEDQIDGFLDDVDEYRGHGVFWVNRDARWSYLAQHAKGI 120 Query 111 PAVGGEPAKNIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFS 170 PAVG EP K +GQLIDEAMD +M ANP+L TLPR+YN+DN+DQRRLGEL+DLFNSARF+ Sbjct 121 PAVGNEPPKQVGQLIDEAMDYLMDANPSLRATLPRIYNRDNVDQRRLGELLDLFNSARFT 180 Query 171 RQGEHRARDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCG 230 QG +ARDL+GEVYEYFL FA+AEGKRGGEF+TP SVV+V+VEVLEP+ GRVYDPCCG Sbjct 181 GQGATKARDLLGEVYEYFLEKFAKAEGKRGGEFYTPASVVRVLVEVLEPTRGRVYDPCCG 240 Query 231 SGGMFVQTEKFIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFA 290 SGGMFVQTEKF+ H + ++S+YGQE E TWRMAKMNLAIHG+ LG RW DTFA Sbjct 241 SGGMFVQTEKFLEAHHREGSEISVYGQELNERTWRMAKMNLAIHGLSGN-LGPRWGDTFA 299 Query 291 RDQHPDVQMDYVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRA 350 RD HPDVQ DYV+AN PFNIKDWARN++DPRW+FGVPPA NANYAWIQHI+ KLAPGG A Sbjct 300 RDIHPDVQADYVLANPPFNIKDWARNDKDPRWKFGVPPAGNANYAWIQHIISKLAPGGSA 359 Query 351 GVVMANGSMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGK 410 GVVMANGSMS+ S GEG IRAQ+VEADLVSCMVALPTQLFRSTGIPVCLWFFAKDK G Sbjct 360 GVVMANGSMSTQSGGEGAIRAQLVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKTVGT 419 Query 411 QGSIDRCGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDV 470 GS+DR G+VLFIDAR +G++VDRAER+L++++I I TFHAWRG+ SA G+ Y D Sbjct 420 GGSVDRSGRVLFIDARSMGNMVDRAERSLSDDDIGLIAGTFHAWRGTASARAAGLEYADK 479 Query 471 PGFCKSATLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLER 530 PGFC SATLAEIKA DYALTPGRYVG VEDDGEPI+EK+ RL+K L + FDES RL + Sbjct 480 PGFCYSATLAEIKAADYALTPGRYVGAAEVEDDGEPIEEKIDRLTKQLFDQFDESERLAK 539 Query 531 VVREQLGRL 539 VVR++LGRL Sbjct 540 VVRQRLGRL 548 >gi|25028883|ref|NP_738937.1| putative type I restriction-modification system methylase [Corynebacterium efficiens YS-314] gi|23494170|dbj|BAC19137.1| putative type I restriction-modification system methylase [Corynebacterium efficiens YS-314] Length=536 Score = 789 bits (2037), Expect = 0.0, Method: Compositional matrix adjust. Identities = 389/536 (73%), Positives = 442/536 (83%), Gaps = 4/536 (0%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MPP K PSTMKELKDTLWKAADKLRGS+ ASQYKDVILGLVFLKYVSDA+ ERR Sbjct 1 MPP-KNTVEATPSTMKELKDTLWKAADKLRGSMDASQYKDVILGLVFLKYVSDAFAERRT 59 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 + EL AEGM + Q LIDD ++Y G+GVF VP +ARW++LA+N KG A G +N Sbjct 60 QLHDELVAEGMTDDQTAMLIDDTDEYTGHGVFWVPDNARWEYLAQNAKGLSANYGNAPRN 119 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IG+L+D+AMDA+M ANP L TLPR+YN++++DQRRLGELIDLFN+ARF+ QG RARDL Sbjct 120 IGELVDDAMDAIMVANPALSATLPRIYNRESVDQRRLGELIDLFNTARFTGQGPGRARDL 179 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 +GEVYEYFL FARAEGKRGGEF+TP VV+V+VEVLEP+SGRVYDPCCGSGGMFVQTEK Sbjct 180 LGEVYEYFLEKFARAEGKRGGEFYTPAGVVRVLVEVLEPTSGRVYDPCCGSGGMFVQTEK 239 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 F+ H+ D +++YGQE E TWRMAKMNLAIHG+ N LG RW DTFARD HP++Q D Sbjct 240 FLDAHNKDRTAIAVYGQELNERTWRMAKMNLAIHGL-NANLGPRWGDTFARDLHPEMQAD 298 Query 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 Y+MAN PFNIKDWARNEEDPRWR+GVPP NNANYAWIQHI+ KLAPGG AGVVMANGSMS Sbjct 299 YIMANPPFNIKDWARNEEDPRWRYGVPPKNNANYAWIQHIISKLAPGGSAGVVMANGSMS 358 Query 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 SNS GEG IRA++VEADLVSCMVALPTQLFRSTGIPVC+WFFAKDK G QG+IDR GQV Sbjct 359 SNSGGEGKIRAELVEADLVSCMVALPTQLFRSTGIPVCVWFFAKDKTVGDQGAIDRTGQV 418 Query 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 LFIDAR LG ++DRAERAL++E+I +I DTFH WRG+ SA KG YED GFC SATL Sbjct 419 LFIDARNLGHMIDRAERALSDEDIAKIADTFHTWRGTPSA--KGRTYEDEAGFCYSATLE 476 Query 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 EIK DYALTPGRYVG +EDDGEPIDEK+ RL K LL+ FDES RL VVREQL Sbjct 477 EIKDADYALTPGRYVGAAEIEDDGEPIDEKIERLKKELLDQFDESERLAAVVREQL 532 >gi|260905625|ref|ZP_05913947.1| N-6 DNA methylase [Brevibacterium linens BL2] Length=532 Score = 786 bits (2031), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/535 (71%), Positives = 440/535 (83%), Gaps = 7/535 (1%) Query 5 KKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRA 64 KK A P+TM ELK TLWKAAD+LRGSLSA+QYKDVILGLVFLKYVSDA++E + +R Sbjct 4 KKTAVAEPTTMNELKATLWKAADRLRGSLSANQYKDVILGLVFLKYVSDAFEEEQSLLRV 63 Query 65 ELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQL 124 E +G++E I +L+ D + Y G G+F+VP +ARW FLAEN KG+ G E + +G L Sbjct 64 EYEEQGIDEEDIAELLLDTDTYVGEGIFLVPEAARWTFLAENAKGQAPSGAEAGRTVGAL 123 Query 125 IDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEV 184 IDEAMD +M+ANP+L GTLPRLYNKDNIDQRRLGEL+DLF+S RFSRQGEH+ARDLMGEV Sbjct 124 IDEAMDQLMRANPSLRGTLPRLYNKDNIDQRRLGELVDLFSSTRFSRQGEHKARDLMGEV 183 Query 185 YEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYE 244 YEYFLG FARAEGKRGGEFFTP VV+ +VE+LEP SGRVYDPCCGSGGMFVQ+EKFI + Sbjct 184 YEYFLGEFARAEGKRGGEFFTPRPVVRTMVEILEPYSGRVYDPCCGSGGMFVQSEKFIED 243 Query 245 HDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMA 304 ++GDP+++++YGQESIEETWRMAKMNLAI+GI+ +GLG +W DTFARD H D QMDYV+A Sbjct 244 NNGDPREIAVYGQESIEETWRMAKMNLAINGIEVQGLGEKWGDTFARDIHADTQMDYVLA 303 Query 305 NLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSN 364 N PFN+K WAR+EEDPRW FGVPP NANYAWIQHIL KL G+AGVVMANGSMSSN+ Sbjct 304 NPPFNLKAWARSEEDPRWTFGVPPEKNANYAWIQHILSKLNDSGKAGVVMANGSMSSNTG 363 Query 365 GEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFID 424 GEGDIRAQIVEADLVSCM+ALPTQLFRSTGIPVC+WFFAK K A R G+VLFID Sbjct 364 GEGDIRAQIVEADLVSCMLALPTQLFRSTGIPVCVWFFAKKKGA-------RAGEVLFID 416 Query 425 ARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKA 484 AR++G ++ RAER+L+NE+I +I TFHAW GS SA YEDVPGFC++ LAEIK Sbjct 417 ARDMGHMISRAERSLSNEDIEKIAGTFHAWIGSPSAEEARREYEDVPGFCRTVPLAEIKE 476 Query 485 TDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 YALTPGRYVG+ +D EPIDEK+ARL L+EAFDESARLE VVREQL RL Sbjct 477 AGYALTPGRYVGSAPEPEDLEPIDEKIARLKGDLIEAFDESARLETVVREQLERL 531 >gi|220911869|ref|YP_002487178.1| N-6 DNA methylase [Arthrobacter chlorophenolicus A6] gi|219858747|gb|ACL39089.1| N-6 DNA methylase [Arthrobacter chlorophenolicus A6] Length=543 Score = 784 bits (2025), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/543 (72%), Positives = 446/543 (83%), Gaps = 6/543 (1%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MPP+ K APSTMKELKDTLWKAADKLRGS+ ASQYKDVILGLVFLKYVSDA+DERR Sbjct 1 MPPKIK-VDLAPSTMKELKDTLWKAADKLRGSMDASQYKDVILGLVFLKYVSDAFDERRN 59 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 I+AEL A+G+ E QI LIDD ++Y GVF V ARW +LAEN KG PA+ G K+ Sbjct 60 QIQAELEADGLNEEQIAQLIDDVDEYTSRGVFWVSGRARWSYLAENAKGLPAMDGAAPKS 119 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IG LID+AMD +M N +L TLPR+YN+DN+DQRRLGEL+DLFNSARF+ QG +ARDL Sbjct 120 IGLLIDDAMDLIMTDNKSLAATLPRIYNRDNVDQRRLGELLDLFNSARFTGQGASKARDL 179 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 +GEVYEYFL FA+AEGKRGGEF+TP VV+V+VEVLEP GRVYDPCCGSGGMFVQ EK Sbjct 180 LGEVYEYFLEKFAKAEGKRGGEFYTPAGVVRVLVEVLEPHRGRVYDPCCGSGGMFVQAEK 239 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQ-- 298 F+ H+ + D+S+YGQE E TWRMAKMNLAIHG+ N L ARW DTFARDQHP++ Sbjct 240 FLEAHNMEGSDISVYGQELNERTWRMAKMNLAIHGL-NANLAARWGDTFARDQHPELTGN 298 Query 299 --MDYVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMAN 356 D++MAN PFNIK W+R+E DPRW++GVPPA NANYAWIQHI+ KLAPGG AGVVMAN Sbjct 299 TGADFIMANPPFNIKVWSRSESDPRWKYGVPPAGNANYAWIQHIISKLAPGGSAGVVMAN 358 Query 357 GSMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDR 416 GSMSSNS GEG+IRAQ+VEADLVSCMVALPTQLFRSTGIPVC WFFAKDK AGK+GSIDR Sbjct 359 GSMSSNSGGEGEIRAQLVEADLVSCMVALPTQLFRSTGIPVCTWFFAKDKTAGKKGSIDR 418 Query 417 CGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKS 476 GQVLFIDAR LG +VDRAERAL++E+I +I +T+HAWRG+ SA G+ YED GFC S Sbjct 419 TGQVLFIDARNLGYMVDRAERALSDEDITKIANTYHAWRGTASAVEAGLTYEDEAGFCYS 478 Query 477 ATLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 A+LAEIKA DYALTPGRYVG VEDDGEPI+EK+ARLSK L F+ES R R+VREQL Sbjct 479 ASLAEIKAADYALTPGRYVGAVDVEDDGEPIEEKIARLSKELFAQFEESERRARLVREQL 538 Query 537 GRL 539 GR+ Sbjct 539 GRV 541 >gi|229822392|ref|YP_002883918.1| N-6 DNA methylase [Beutenbergia cavernae DSM 12333] gi|229568305|gb|ACQ82156.1| N-6 DNA methylase [Beutenbergia cavernae DSM 12333] Length=541 Score = 781 bits (2017), Expect = 0.0, Method: Compositional matrix adjust. Identities = 388/543 (72%), Positives = 445/543 (82%), Gaps = 6/543 (1%) Query 1 MPPRKKQA---PQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDE 57 MPPR+K+A P A +TMKELKDTLWKAADKLRGS+ ASQYKDVILGLVFLKYVSDA+DE Sbjct 1 MPPRRKRAEALPTAATTMKELKDTLWKAADKLRGSMDASQYKDVILGLVFLKYVSDAFDE 60 Query 58 RREAIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEP 117 RR I AELAA+G+ E Q L+++ ++Y+ GVF VP ARW +LA++ KG+PA E Sbjct 61 RRAVIAAELAADGIGEEQAGPLLEEVDEYRAAGVFWVPPRARWGYLAQHAKGRPAGDPEG 120 Query 118 AKNIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRA 177 IG+L+DEAM +M NP L TLP+++NK+N+DQRRLGELIDLFNSARF+ G +A Sbjct 121 QATIGELVDEAMVLIMGTNPALATTLPQIFNKENVDQRRLGELIDLFNSARFTGDGARKA 180 Query 178 RDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQ 237 RD++GEVYEYFLG FA AEGKRGGEF+TPP VV+V+VEVLEP GRVYDPCCGSGGMFVQ Sbjct 181 RDVLGEVYEYFLGKFAAAEGKRGGEFYTPPGVVRVLVEVLEPYRGRVYDPCCGSGGMFVQ 240 Query 238 TEKFIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDV 297 EKFI H DP+ +S+YGQE E TWRMAKMNLA+HG+ + LG RW DTFARD HPDV Sbjct 241 AEKFIERHGEDPQAISVYGQELNERTWRMAKMNLAVHGLTAQ-LGPRWGDTFARDVHPDV 299 Query 298 QMDYVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANG 357 QMD+VMAN PFNIKDWARN ED RW+FGVPPA NANYAWIQHIL KLAPGG AGVVMANG Sbjct 300 QMDFVMANPPFNIKDWARNAEDARWKFGVPPAGNANYAWIQHILSKLAPGGSAGVVMANG 359 Query 358 SMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRC 417 SMSSNS GEG+IRA +VE DLVSCMVALPTQLFRSTGIPVC+WFFAK KAAG GS+DR Sbjct 360 SMSSNSVGEGEIRAALVEVDLVSCMVALPTQLFRSTGIPVCVWFFAKSKAAGASGSVDRT 419 Query 418 GQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSA 477 GQVLFIDAR LG +V RAER L++E+I RI TFHAWRG+ SA+ G YEDVPGFC SA Sbjct 420 GQVLFIDARNLGHMVTRAERELSDEDIARIAGTFHAWRGAPSAS--GASYEDVPGFCYSA 477 Query 478 TLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLG 537 TL+EIK YAL PGRYVG P VEDDGEPI+EK+ RL+ L F+ESARLE+VVREQLG Sbjct 478 TLSEIKEAGYALAPGRYVGAPEVEDDGEPIEEKIERLTAELFAQFEESARLEQVVREQLG 537 Query 538 RLR 540 R+R Sbjct 538 RVR 540 >gi|259507945|ref|ZP_05750845.1| type I restriction-modification system, M subunit [Corynebacterium efficiens YS-314] gi|259164440|gb|EEW48994.1| type I restriction-modification system, M subunit [Corynebacterium efficiens YS-314] Length=523 Score = 778 bits (2010), Expect = 0.0, Method: Compositional matrix adjust. Identities = 382/522 (74%), Positives = 435/522 (84%), Gaps = 3/522 (0%) Query 15 MKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEES 74 MKELKDTLWKAADKLRGS+ ASQYKDVILGLVFLKYVSDA+ ERR + EL AEGM + Sbjct 1 MKELKDTLWKAADKLRGSMDASQYKDVILGLVFLKYVSDAFAERRTQLHDELVAEGMTDD 60 Query 75 QIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMK 134 Q LIDD ++Y G+GVF VP +ARW++LA+N KG A G +NIG+L+D+AMDA+M Sbjct 61 QTAMLIDDTDEYTGHGVFWVPDNARWEYLAQNAKGLSANYGNAPRNIGELVDDAMDAIMV 120 Query 135 ANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFAR 194 ANP L TLPR+YN++++DQRRLGELIDLFN+ARF+ QG RARDL+GEVYEYFL FAR Sbjct 121 ANPALSATLPRIYNRESVDQRRLGELIDLFNTARFTGQGPGRARDLLGEVYEYFLEKFAR 180 Query 195 AEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSI 254 AEGKRGGEF+TP VV+V+VEVLEP+SGRVYDPCCGSGGMFVQTEKF+ H+ D +++ Sbjct 181 AEGKRGGEFYTPAGVVRVLVEVLEPTSGRVYDPCCGSGGMFVQTEKFLDAHNKDRTAIAV 240 Query 255 YGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKDWA 314 YGQE E TWRMAKMNLAIHG+ N LG RW DTFARD HP++Q DY+MAN PFNIKDWA Sbjct 241 YGQELNERTWRMAKMNLAIHGL-NANLGPRWGDTFARDLHPEMQADYIMANPPFNIKDWA 299 Query 315 RNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIV 374 RNEEDPRWR+GVPP NNANYAWIQHI+ KLAPGG AGVVMANGSMSSNS GEG IRA++V Sbjct 300 RNEEDPRWRYGVPPKNNANYAWIQHIISKLAPGGSAGVVMANGSMSSNSGGEGKIRAELV 359 Query 375 EADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLVDR 434 EADLVSCMVALPTQLFRSTGIPVC+WFFAKDK G QG+IDR GQVLFIDAR LG ++DR Sbjct 360 EADLVSCMVALPTQLFRSTGIPVCVWFFAKDKTVGDQGAIDRTGQVLFIDARNLGHMIDR 419 Query 435 AERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPGRY 494 AERAL++E+I +I DTFH WRG+ SA KG YED GFC SATL EIK DYALTPGRY Sbjct 420 AERALSDEDIAKIADTFHTWRGTPSA--KGRTYEDEAGFCYSATLEEIKDADYALTPGRY 477 Query 495 VGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 VG +EDDGEPIDEK+ RL K LL+ FDES RL VVREQL Sbjct 478 VGAAEIEDDGEPIDEKIERLKKELLDQFDESERLAAVVREQL 519 >gi|319951306|ref|ZP_08025140.1| putative type I restriction/modification system DNA methylase [Dietzia cinnamea P4] gi|319435021|gb|EFV90307.1| putative type I restriction/modification system DNA methylase [Dietzia cinnamea P4] Length=535 Score = 758 bits (1956), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/531 (68%), Positives = 435/531 (82%), Gaps = 5/531 (0%) Query 9 PQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAA 68 P ST KELKDTLWKAADKLRGS+ ASQYKDV+LGLVFLKYVSDA++ERR+AIR EL+ Sbjct 9 PMEASTPKELKDTLWKAADKLRGSMDASQYKDVVLGLVFLKYVSDAFEERRDAIREELSG 68 Query 69 EGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEA 128 E +E+ + + ++D ++Y G GVF VP ARW++L+ + KG PA A++IG+LID A Sbjct 69 E--DEAYLAETLEDADEYLGSGVFWVPAEARWEYLSRHAKGIPASSTNDAQSIGELIDAA 126 Query 129 MDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYF 188 M A+M+AN +L GTLP L+ +DN++QRRLGEL+DLFN+ARF+ G +ARDL+GEVYEYF Sbjct 127 MRALMQANESLVGTLPVLFGRDNVEQRRLGELVDLFNAARFTGGGASKARDLLGEVYEYF 186 Query 189 LGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGD 248 L FA+AEGKRGGEF+TPP VV+ +VE+LEP SGRVYDPCCGSGGMFVQTEKF+ H D Sbjct 187 LDKFAKAEGKRGGEFYTPPVVVRTLVEILEPHSGRVYDPCCGSGGMFVQTEKFLEGHKED 246 Query 249 PKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPF 308 P +V++YGQE E TWRMAKMNLAIHGID++GLG+RW DTFARD HPD+Q DYVMAN PF Sbjct 247 PTNVAVYGQELNERTWRMAKMNLAIHGIDSQGLGSRWGDTFARDIHPDMQADYVMANPPF 306 Query 309 NIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGD 368 NIKDWAR E+DPRW +GVPP NANYAW+QHIL KLAP G AGVVMANG+M+++++GEGD Sbjct 307 NIKDWARREDDPRWVYGVPPKRNANYAWMQHILSKLAPNGEAGVVMANGTMTTSTSGEGD 366 Query 369 IRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDAREL 428 IR +VE D+V C+VALP QLFR+TGIPVC+WFFAK+K AGK GS+DR GQVLFIDAREL Sbjct 367 IRKAMVEGDVVQCIVALPGQLFRATGIPVCVWFFAKNKTAGKGGSVDRRGQVLFIDAREL 426 Query 429 GDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYA 488 G ++DR ER L+ E++ RI +TF +WRG SA + YEDVPGFCKSATL EIKA YA Sbjct 427 GHMIDRVERTLSEEDLQRIAETFRSWRGRPSAVGE---YEDVPGFCKSATLEEIKAAGYA 483 Query 489 LTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 LTPGRYVG P E+D EPIDEK+ARL+ L A DESAR + +VREQLGRL Sbjct 484 LTPGRYVGVPEAEEDLEPIDEKIARLTGELTAALDESARKDALVREQLGRL 534 >gi|183981973|ref|YP_001850264.1| type I restriction/modification system DNA methylase HsdM [Mycobacterium marinum M] gi|183175299|gb|ACC40409.1| type I restriction/modification system DNA methylase HsdM [Mycobacterium marinum M] Length=484 Score = 726 bits (1875), Expect = 0.0, Method: Compositional matrix adjust. Identities = 358/530 (68%), Positives = 411/530 (78%), Gaps = 49/530 (9%) Query 11 APSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEG 70 APSTMKELKDTLWK A+KLRGS+ ASQYKDVILGLVFLK+VSDA D R+ Sbjct 2 APSTMKELKDTLWKGAEKLRGSIPASQYKDVILGLVFLKFVSDARDGRKP---------- 51 Query 71 MEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMD 130 FVVP ARW+ LA N K + +IGQLID AM Sbjct 52 ---------------------FVVPPEARWEALAGNAK---------SPDIGQLIDTAML 81 Query 131 AVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLG 190 +VM ANP+L TLP+LY+K +DQRRLGEL+++ +ARFS + HRARDLMGEVYEYFLG Sbjct 82 SVMTANPSLAATLPQLYHK--VDQRRLGELVEVLGAARFSGRPSHRARDLMGEVYEYFLG 139 Query 191 NFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPK 250 NFARAEG+RGGEFFTPPSVV+VIVE+LEPSSGR+YDPCCGSGGMFVQTE+FI HDGDP Sbjct 140 NFARAEGRRGGEFFTPPSVVRVIVEILEPSSGRIYDPCCGSGGMFVQTERFICAHDGDPA 199 Query 251 DVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNI 310 +SIYGQES+E+TWRMAKMNLA+HGID+ GLGARW DTFA DQH V MDYVMAN PFNI Sbjct 200 QISIYGQESVEQTWRMAKMNLAVHGIDDAGLGARWGDTFATDQHDGVPMDYVMANPPFNI 259 Query 311 KDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIR 370 KDWAR+E+DPRWRFG PPA NAN+AWIQHIL KLAP G+AGVVMANGSMSS +NGE IR Sbjct 260 KDWARDEQDPRWRFGTPPAANANFAWIQHILSKLAPTGQAGVVMANGSMSSKTNGEDRIR 319 Query 371 AQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGD 430 A I++ADLVSCMVALPTQLFRSTGIPVCLWFFAKDK A R GQVLFIDAR LG Sbjct 320 AGIIDADLVSCMVALPTQLFRSTGIPVCLWFFAKDKKA-------RSGQVLFIDARGLGS 372 Query 431 LVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALT 490 +VDR ER LT++++ RIGDT+H W GS S+ KG +Y+D+PGFC+SA+L EI+A Y LT Sbjct 373 MVDRCERTLTDDDVARIGDTYHGWFGSASSVAKGTVYQDIPGFCRSASLDEIRAEGYVLT 432 Query 491 PGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 PGRYVGT A DGEPI +K+ARL+ LL A DES +L+ VR QLGR+R Sbjct 433 PGRYVGTGASCADGEPIGDKLARLTTQLLAALDESTKLDEAVRAQLGRVR 482 >gi|334336398|ref|YP_004541550.1| Site-specific DNA-methyltransferase (adenine-specific) [Isoptericola variabilis 225] gi|334106766|gb|AEG43656.1| Site-specific DNA-methyltransferase (adenine-specific) [Isoptericola variabilis 225] Length=566 Score = 714 bits (1843), Expect = 0.0, Method: Compositional matrix adjust. Identities = 366/573 (64%), Positives = 433/573 (76%), Gaps = 41/573 (7%) Query 1 MPPRKKQAPQAPST---MKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDE 57 MPPRKK A +T MKELKDTLWKAADKLRGS+ ASQYKDVILGLVFLKYVSDA++E Sbjct 1 MPPRKKAAAPTVATATTMKELKDTLWKAADKLRGSMDASQYKDVILGLVFLKYVSDAFEE 60 Query 58 RREAIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEP 117 RR AI E A+G+ E L++D ++Y+ G F VP ARW +LA++ KG+ A EP Sbjct 61 RRAAILEECLADGLSEDDAAPLLEDVDEYRRAGAFWVPERARWGYLAQHAKGRSATPDEP 120 Query 118 AKNIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSR-----Q 172 +IGQL+D+AM +M +NPTL GTLP ++N+D++DQRRLGEL+DLF+SARF+ Sbjct 121 EASIGQLVDDAMLLLMGSNPTLKGTLPTIFNRDSVDQRRLGELVDLFSSARFTGVMADGT 180 Query 173 GEHRARDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSG 232 +ARD++GEVYEYFLG FA AEGKRGGEF+TPP VV+V+VEVLEP GRVYDPCCGSG Sbjct 181 KVSKARDVLGEVYEYFLGKFAAAEGKRGGEFYTPPGVVRVLVEVLEPYRGRVYDPCCGSG 240 Query 233 GMFVQTEKFIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARD 292 GMFVQ EKF+ H DP+ +S++GQE E TWRMAKMNLA+HG+ LG RW DTFARD Sbjct 241 GMFVQAEKFLERHGADPQAISVFGQELNERTWRMAKMNLAVHGLTGN-LGPRWGDTFARD 299 Query 293 QHPDVQMDYVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGV 352 HP++Q DYV+AN PFNIKDWARN +D RW+FGVPPA NANYAWIQHIL KLAPGG AGV Sbjct 300 LHPELQADYVLANPPFNIKDWARNTDDARWKFGVPPAGNANYAWIQHILSKLAPGGSAGV 359 Query 353 VMANGSMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQG 412 VMANGSMSSNS GEG+IRAQ+VEADLVSCMVALPTQLFRSTGIPVC+WFFAKDK A Sbjct 360 VMANGSMSSNSGGEGEIRAQLVEADLVSCMVALPTQLFRSTGIPVCVWFFAKDKGA---- 415 Query 413 SIDRCGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGI------- 465 R G+VLFIDAR LG +VDRAERAL++++I +I DT+HAW+ S + + Sbjct 416 ---RAGEVLFIDARNLGHMVDRAERALSDDDIAKIADTYHAWKRGPSPESEPVETLPVVE 472 Query 466 ------------------MYEDVPGFCKSATLAEIKATDYALTPGRYVGTPAVEDDGEPI 507 Y D+PGFC SATLAEIK YALTPGRYVG VEDDGEPI Sbjct 473 PVETEPVETEPVVEPVETTYSDIPGFCYSATLAEIKDAGYALTPGRYVGAAEVEDDGEPI 532 Query 508 DEKMARLSKALLEAFDESARLERVVREQLGRLR 540 ++K+ RL+ L FDESARLE+VVREQLGR+ Sbjct 533 EQKIERLTAELFAQFDESARLEQVVREQLGRVH 565 >gi|227505724|ref|ZP_03935773.1| adenine-specific DNA-methyltransferase [Corynebacterium striatum ATCC 6940] gi|227197692|gb|EEI77740.1| adenine-specific DNA-methyltransferase [Corynebacterium striatum ATCC 6940] Length=543 Score = 712 bits (1837), Expect = 0.0, Method: Compositional matrix adjust. Identities = 334/530 (64%), Positives = 416/530 (79%), Gaps = 1/530 (0%) Query 11 APSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEG 70 + +T+KELKDTLWKAADKLRGS+ ASQYKD++LGLVFLKYV+DA+D RR +RAE G Sbjct 15 SATTLKELKDTLWKAADKLRGSMDASQYKDIVLGLVFLKYVTDAFDARRAELRAEGEERG 74 Query 71 MEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMD 130 E I++ ++D + Y+ VF V ARW FL +N+KGK A G+ ++IG+LID AM Sbjct 75 DSEEYIQEDLEDIDAYREKNVFWVDPIARWTFLRDNSKGKSADAGQEYQSIGKLIDNAMK 134 Query 131 AVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLG 190 +M N +L GTLP + +++DQRRLGELIDLF++ RF+ +G RARDL+GEVYEYFL Sbjct 135 QLMLDNESLLGTLPTNFASESVDQRRLGELIDLFSTTRFTAEGPERARDLLGEVYEYFLE 194 Query 191 NFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPK 250 FARAEGKRGGEF+TP VV+ +VE+LEP+ GRVYDPCCGSGGMFVQ EKF+ + D Sbjct 195 KFARAEGKRGGEFYTPRPVVRTLVEILEPTQGRVYDPCCGSGGMFVQAEKFLETTEKDRT 254 Query 251 DVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNI 310 ++IYGQE E TWRMAKMNLAIH I + GLG RW+DTFARD HPD QMDYVMAN PFNI Sbjct 255 ALAIYGQELNERTWRMAKMNLAIHAISSAGLGERWADTFARDIHPDKQMDYVMANPPFNI 314 Query 311 KDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIR 370 KDW+RNEED RW++GVPP NAN+AW+QHI+ KL P G AGVVMANG+M+SNS+GEGDIR Sbjct 315 KDWSRNEEDTRWKYGVPPKRNANFAWMQHIISKLTPQGEAGVVMANGTMTSNSSGEGDIR 374 Query 371 AQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGD 430 +VE D+VSC++ALP QLFR T IPVC+WFFAKDK AG +G+IDR QVLFIDARELG Sbjct 375 KAMVEDDIVSCVIALPAQLFRGTQIPVCVWFFAKDKKAGSKGTIDRTNQVLFIDARELGH 434 Query 431 LVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALT 490 ++DR ER ++E+I +I DT+ WRG +++A KG YED+ GFCKSA+L +I+ D+A+T Sbjct 435 MIDRTERTFSDEDIQKIADTYRLWRG-RTSAPKGKAYEDIAGFCKSASLDDIRDADFAMT 493 Query 491 PGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 PGRYVG E+D EPIDEK+ARL+ L D++ARL+ VVREQLGRL+ Sbjct 494 PGRYVGFAEAEEDDEPIDEKIARLTGELTATLDDAARLDEVVREQLGRLK 543 >gi|38234849|ref|NP_940616.1| putative type I restriction/modification system DNA methylase [Corynebacterium diphtheriae NCTC 13129] gi|38201113|emb|CAE50837.1| Putative type I restriction/modification system DNA methylase [Corynebacterium diphtheriae] Length=535 Score = 708 bits (1828), Expect = 0.0, Method: Compositional matrix adjust. Identities = 339/540 (63%), Positives = 415/540 (77%), Gaps = 5/540 (0%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 M +KK+ Q PST KE+KDTLWK+ADKLRGS+ ASQYKDV LGLVFLKYVSD+++ER++ Sbjct 1 MVRKKKEVAQVPSTSKEIKDTLWKSADKLRGSMDASQYKDVALGLVFLKYVSDSFEERQK 60 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 IRAEL +G +E I + + D + Y VF V +ARW FL + +KG G K+ Sbjct 61 EIRAELEGKGFDEEYILEDLADVDAYTSENVFWVASNARWDFLKKYSKGMDLEG--KHKS 118 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IG+LIDEAM +M N +L GTLP++Y KDNIDQRRLGEL+DLF+S F+ + +ARDL Sbjct 119 IGKLIDEAMQQLMADNESLLGTLPQIYGKDNIDQRRLGELVDLFSSTYFASTKDKKARDL 178 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 +GEVYEYFL FA+AEGKRGGEF+TP VV+ +VE+LEP+ GRVYDPCCGSGGMFVQ EK Sbjct 179 LGEVYEYFLDKFAKAEGKRGGEFYTPQPVVRTLVEILEPTEGRVYDPCCGSGGMFVQAEK 238 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 F+ D ++++YGQE E TWRMAKMNLAIH I + GLG RW DTFARD H +MD Sbjct 239 FLEVTKRDRSNIAVYGQELNERTWRMAKMNLAIHAISSSGLGERWGDTFARDIHAGTKMD 298 Query 301 YVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMS 360 Y+MAN PFNIKDW RNEED RW++GVPPA NAN+AWIQHI+ KL G AGVVMANG+M+ Sbjct 299 YIMANPPFNIKDWIRNEEDARWKYGVPPAKNANFAWIQHIISKLKDHGEAGVVMANGTMT 358 Query 361 SNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQV 420 S S+GEG+IR +VE D+VSC++ALP QLFR TGIPVC+WFFAKDK+AG GS+DR G+V Sbjct 359 SQSSGEGEIRKNMVEDDVVSCVIALPAQLFRGTGIPVCVWFFAKDKSAGVGGSVDRRGEV 418 Query 421 LFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLA 480 L IDAR+LG ++DR ERA ++E+I +I + F WRG KSA + YED GFCKSAT+ Sbjct 419 LLIDARQLGHMIDRTERAFSDEDITKIANAFRTWRGRKSAEGE---YEDEAGFCKSATIE 475 Query 481 EIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 EI+ YALTPGRYVG P E+D EPIDEK+ARL+ L A DESARL+ VVREQLGRL+ Sbjct 476 EIREAGYALTPGRYVGMPEAEEDDEPIDEKIARLTAELTAALDESARLDAVVREQLGRLK 535 >gi|296270473|ref|YP_003653105.1| site-specific DNA-methyltransferase [Thermobispora bispora DSM 43833] gi|296093260|gb|ADG89212.1| Site-specific DNA-methyltransferase (adenine- specific) [Thermobispora bispora DSM 43833] Length=540 Score = 692 bits (1787), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/545 (64%), Positives = 426/545 (79%), Gaps = 19/545 (3%) Query 1 MPPRKKQAPQAPS-----TMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAY 55 MPPR+K+A + + TM +L+DTLWKAADKLRGS+ A+QYKD +LGLVFLKYVSDA+ Sbjct 1 MPPRRKKATEQAALPGMPTMADLRDTLWKAADKLRGSMDAAQYKDFVLGLVFLKYVSDAF 60 Query 56 DERREAIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGG 115 +ERREAIR E+ +G+ ES+++ +DD ++Y G+GVF VP ARW LA + K Sbjct 61 EERREAIREEILEQGIPESRLDMFLDDKDEYIGHGVFWVPEEARWSHLAAHAK------- 113 Query 116 EPAKNIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEH 175 ++ IG+LID AMDA+MK+N +L G LP+++N+DN+DQRRLGEL+DL ARF+ G+ Sbjct 114 --SEGIGELIDRAMDAIMKSNQSLAGVLPKIFNRDNVDQRRLGELVDLIGDARFTGHGDR 171 Query 176 RARDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMF 235 ARD++GEVYEYFL FARAEGKRGGEF+TP SVVK++VEVLEP +GRVYDPCCGSGGMF Sbjct 172 PARDVLGEVYEYFLEKFARAEGKRGGEFYTPASVVKLLVEVLEPYAGRVYDPCCGSGGMF 231 Query 236 VQTEKFIYEHDG--DPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQ 293 VQ EKF+ H G D+++YGQES E TWR+AKMNLAIHGI LG RW+DTF D+ Sbjct 232 VQAEKFVIAHRGIQHKDDIAVYGQESNERTWRLAKMNLAIHGISGN-LGPRWADTFREDK 290 Query 294 HPDVQMDYVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVV 353 HPD++ D+V+AN PFN+ DW+R +DPRWRFG PPANNAN+AW+QHI+ KLA G AGVV Sbjct 291 HPDLKADFVLANPPFNMSDWSRQVDDPRWRFGTPPANNANFAWLQHIISKLAERGTAGVV 350 Query 354 MANGSMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKA-AGKQG 412 +ANGSMSS +GEG+IRA IVEADLVSCMVALP QLFR+T IP CLWFF KDK+ G + Sbjct 351 LANGSMSSKQSGEGEIRAAIVEADLVSCMVALPPQLFRTTQIPACLWFFDKDKSPQGAKR 410 Query 413 SIDRCGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPG 472 DR G+VLFIDAR +G +VDR ER LT ++I RI DT+HAWRG+ SA K + YEDVPG Sbjct 411 LADRRGEVLFIDARNMGTMVDRTERVLTADDIARIADTYHAWRGTASARAKNLKYEDVPG 470 Query 473 FCKSATLAEIKATDYALTPGRYVGTPAVED-DGEPIDEKMARLSKALLEAFDESARLERV 531 FC SATL EI+ D+ LTPGRYVG P V++ D EPI +K+ARL+K L F+ESARLE+V Sbjct 471 FCYSATLEEIRQHDHVLTPGRYVGAPEVQNEDDEPIADKIARLTKELYAHFEESARLEKV 530 Query 532 VREQL 536 VREQL Sbjct 531 VREQL 535 >gi|172039827|ref|YP_001799541.1| type I restriction-modification system, methyltransferase subunit [Corynebacterium urealyticum DSM 7109] gi|171851131|emb|CAQ04107.1| type I restriction-modification system, methyltransferase subunit [Corynebacterium urealyticum DSM 7109] Length=528 Score = 685 bits (1768), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/529 (63%), Positives = 406/529 (77%), Gaps = 3/529 (0%) Query 11 APSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEG 70 P+ +KE +DTLWKAADKLRGS+ ASQYKD++LGLVFLKYV+DA+D RR + AEL EG Sbjct 2 TPTPIKEFEDTLWKAADKLRGSMDASQYKDIVLGLVFLKYVTDAFDARRLELLAELEEEG 61 Query 71 MEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMD 130 +I + ++D + Y VF V ARW +L ++KGK G K+IG+LIDEA + Sbjct 62 ATAEEIAEELEDRDAYLEKNVFWVAKEARWDYLQRHSKGKTDDAGGEFKSIGKLIDEAAE 121 Query 131 AVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLG 190 A+M N +L GTLP YN D++DQRRLGEL+DLF++ RF+ +G RARDL+GEVYEYFL Sbjct 122 ALMTDNLSLEGTLPHNYNSDSVDQRRLGELVDLFSTTRFTAEGPERARDLLGEVYEYFLA 181 Query 191 NFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPK 250 FA AEGKRGGEF+TP SVV+ +VE+LEP+ GRVYDPCCGSGGMFVQ EKF+ HD DP Sbjct 182 RFASAEGKRGGEFYTPRSVVRTLVEILEPTEGRVYDPCCGSGGMFVQAEKFLDAHDKDPS 241 Query 251 DVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNI 310 ++IYGQE E TWR+A+MNLAIH +++KGLG RW DTFARD HP V+MDYV+AN PFNI Sbjct 242 AIAIYGQELNERTWRLARMNLAIHALNSKGLGERWGDTFARDIHPGVEMDYVLANPPFNI 301 Query 311 KDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIR 370 KDW RN +D RW +GVPPA NAN+ W+QHI+ KL+ G AGVVMANG+M+SN++GEG+IR Sbjct 302 KDWVRNTDDKRWSYGVPPAKNANFGWMQHIISKLSAQGEAGVVMANGTMTSNTSGEGEIR 361 Query 371 AQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGD 430 ++E D+VSC+V LP QLFR T IPVC+WFFAKDK AG +G +DR G+ L IDARELG Sbjct 362 KNMLEDDIVSCVVTLPAQLFRGTQIPVCVWFFAKDKGAGSKGFVDRRGEFLLIDARELGH 421 Query 431 LVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALT 490 +VDR ER ++E+I +I +TF WRG SA + YED PG+CKS +L EI+ DYALT Sbjct 422 MVDRTERTFSDEDIQKIANTFRTWRGRSSAEGE---YEDAPGYCKSVSLDEIREADYALT 478 Query 491 PGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 PGRYVG E+DGEPIDEK+ARL+ L A DESARL VVREQLGRL Sbjct 479 PGRYVGFAEEEEDGEPIDEKIARLTAELTAALDESARLNAVVREQLGRL 527 >gi|342858378|ref|ZP_08715033.1| type I restriction/modification system DNA methylase HsdM [Mycobacterium colombiense CECT 3035] gi|342134082|gb|EGT87262.1| type I restriction/modification system DNA methylase HsdM [Mycobacterium colombiense CECT 3035] Length=468 Score = 660 bits (1703), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/528 (64%), Positives = 385/528 (73%), Gaps = 63/528 (11%) Query 13 STMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGME 72 ST KELK TLWKAA+KLRGSLSA +YKDVILGLVFLK VS+A+ Sbjct 4 STSKELKATLWKAAEKLRGSLSAGEYKDVILGLVFLKRVSEAH----------------- 46 Query 73 ESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAV 132 WK LA+N + +G+L D+AMDAV Sbjct 47 ---------------------------WKALADNVG---------SGELGRLADDAMDAV 70 Query 133 MKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNF 192 M ANP L GTLPRLY +N+D RRL EL+ + + AR G RA DLMGEVYEYFLGNF Sbjct 71 MTANPALAGTLPRLY--ENLDPRRLAELVTVLDGARIG-DGGGRAGDLMGEVYEYFLGNF 127 Query 193 ARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDV 252 ARAEG+RGGEFFTPPSVV+++VEVLEP+ GRVYDPCCGSGGMFVQTE FI E DGDP V Sbjct 128 ARAEGRRGGEFFTPPSVVRLLVEVLEPTGGRVYDPCCGSGGMFVQTEHFIAERDGDPAKV 187 Query 253 SIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKD 312 ++YGQES+E+TWRMAKMNLA+HGID+ GLG R +DT A D H VQMDYV+AN PFNIKD Sbjct 188 TLYGQESVEQTWRMAKMNLAVHGIDHAGLGPRCADTLAVDLHAGVQMDYVLANPPFNIKD 247 Query 313 WARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQ 372 WAR+E DPRWRFGVPPA++ANYAWIQHIL KLAPGG AGVVMANGSMSSN+ GEG IRA+ Sbjct 248 WARDEADPRWRFGVPPASSANYAWIQHILSKLAPGGAAGVVMANGSMSSNAMGEGGIRAR 307 Query 373 IVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLV 432 IV+ADLVSC+VALP QLFRSTGIPVC+WFFA DKA R QVLF+DAR LG LV Sbjct 308 IVDADLVSCVVALPAQLFRSTGIPVCVWFFATDKA-------HRSAQVLFVDARGLGYLV 360 Query 433 DRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPG 492 DRAERALT EEI RI DT+HAW G+ SA KG+ Y+DVPGFC+S + ++A Y LTPG Sbjct 361 DRAERALTREEIARIADTYHAWSGTASALAKGLSYQDVPGFCQSVPVEAVRAAGYPLTPG 420 Query 493 RYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 RYV P DDGEP +K+ARL+ LL A D+SAR E VVR+Q+ RLR Sbjct 421 RYVDAPTAPDDGEPAADKIARLTGDLLAALDDSARAETVVRQQVKRLR 468 >gi|271968782|ref|YP_003342978.1| Site-specific DNA-methyltransferase [Streptosporangium roseum DSM 43021] gi|270511957|gb|ACZ90235.1| Site-specific DNA-methyltransferase (adenine- specific) [Streptosporangium roseum DSM 43021] Length=544 Score = 660 bits (1702), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/547 (58%), Positives = 412/547 (76%), Gaps = 17/547 (3%) Query 1 MPPRKKQAP-----QAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAY 55 MPPRK+ P + S+ KE++D LWKAADKLRGS+ A+QYK+ +LGLVFLKYVSDA+ Sbjct 1 MPPRKRATPGQGELLSMSSTKEIQDILWKAADKLRGSMDAAQYKEFVLGLVFLKYVSDAF 60 Query 56 DERREAIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGG 115 ERR + A+ + E + +++ ++Y VF VP ARW ++++N + AV G Sbjct 61 AERRATLAADPELAELPEHRRAAFLEEKDEYTEANVFWVPPPARWDYISDNAQS--AVDG 118 Query 116 EPAKNIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEH 175 +G+L+D+AMDA+MK NPTL G LP+++N+DN+D++RL EL+DL + ARF+ G Sbjct 119 -----VGKLLDDAMDAIMKENPTLTGVLPKIFNRDNVDKKRLKELVDLISDARFTGHGAR 173 Query 176 RARDLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMF 235 A+D++GE YEYFL FARAEGKR GEF+TP SVV+++VE+LEP GRVYDPCCGSGGMF Sbjct 174 PAQDVLGETYEYFLERFARAEGKRAGEFYTPASVVRLLVEILEPYEGRVYDPCCGSGGMF 233 Query 236 VQTEKFIYEHDG--DPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQ 293 VQ KF+ H G D+++YGQE+ E TWR+AKMNLAIHG+D KG+G RW+DTF D+ Sbjct 234 VQAGKFVTAHAGRDHTHDIAVYGQETNERTWRLAKMNLAIHGMDPKGVGDRWADTFDDDK 293 Query 294 HPDVQMDYVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVV 353 PD++ D+VMAN PFN+ DWARN D RW +GVPP +NANYAW+QHI++KL G AGVV Sbjct 294 LPDLKADFVMANPPFNLSDWARNVGDRRWMYGVPPQSNANYAWLQHIVFKLGERGSAGVV 353 Query 354 MANGSMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKA-AGKQG 412 +ANGSM+S +GEG+IR ++V+ADLV+CMVALP LFR+T IP CLWF KDK G + Sbjct 354 LANGSMASKQSGEGEIRTKLVQADLVACMVALPGNLFRTTAIPACLWFLTKDKTPQGAKA 413 Query 413 SIDRCGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPG 472 +R G+VLFIDAR LG +VDR ER LT+E++ RI DT+HAWRG++SA KG+ YE+V G Sbjct 414 LAERRGEVLFIDARNLGTMVDRTERILTDEDLARIADTYHAWRGTRSARAKGLKYENVAG 473 Query 473 FCKSATLAEIKATDYALTPGRYVGTPAVED--DGEPIDEKMARLSKALLEAFDESARLER 530 FC SA+L EI+ D+ LTPGRYVG VE+ D EP++E++ARL+K L E F+ESARLE+ Sbjct 474 FCHSASLEEIREHDFVLTPGRYVGATEVEEDPDAEPVEERVARLTKELFEHFEESARLEK 533 Query 531 VVREQLG 537 VVREQLG Sbjct 534 VVREQLG 540 >gi|296171676|ref|ZP_06852890.1| type I modification enzyme [Mycobacterium parascrofulaceum ATCC BAA-614] gi|295894037|gb|EFG73800.1| type I modification enzyme [Mycobacterium parascrofulaceum ATCC BAA-614] Length=457 Score = 657 bits (1694), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/528 (64%), Positives = 387/528 (74%), Gaps = 73/528 (13%) Query 13 STMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGME 72 +T KEL+DTLWKAA+KLRGSLSA QYKDV+LGLVFL++ +A Sbjct 3 ATDKELEDTLWKAANKLRGSLSAGQYKDVVLGLVFLEHAGEA------------------ 44 Query 73 ESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAV 132 WK L VG + IG+L+D+AM+ Sbjct 45 --------------------------EWKSL---------VGNADSPGIGRLVDDAMEVA 69 Query 133 MKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNF 192 LPRLY +N+D RR+GEL+ L ++AR +G ARDLMGE+YEYFLGNF Sbjct 70 ---------ALPRLY--ENLDPRRVGELVCLLDAARLGERGG--ARDLMGELYEYFLGNF 116 Query 193 ARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDV 252 ARAEG+RGGEFFTPPSVV+VIVEVLEP+SGRVYDPCCGSGGMFVQTE+F+ EHDGD + Sbjct 117 ARAEGRRGGEFFTPPSVVRVIVEVLEPASGRVYDPCCGSGGMFVQTERFVAEHDGDSAKI 176 Query 253 SIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKD 312 S +GQES+E+TWR+AKMNLA+HGID+ GLGARW DT DQH +QMDYV+AN PFNIK+ Sbjct 177 SFWGQESVEQTWRLAKMNLAVHGIDDTGLGARWGDTLLADQHAGIQMDYVLANPPFNIKE 236 Query 313 WARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQ 372 WAR+E DPRWRFGVPPA NANYAWIQHIL KLAPGG+AGVVMANGSMSSN+ EG+IRA+ Sbjct 237 WARDERDPRWRFGVPPAGNANYAWIQHILSKLAPGGKAGVVMANGSMSSNALREGEIRAR 296 Query 373 IVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLV 432 IV+ADLVSCMVALP QLFRST IPVCLWFF DK R GQVLFIDAR LG LV Sbjct 297 IVDADLVSCMVALPAQLFRSTPIPVCLWFFDTDKGT-------RSGQVLFIDARGLGHLV 349 Query 433 DRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPG 492 DRAERALT EEIVRIGDT+HAW G SAA KG+ Y DVPGFC SA+L +I A Y LTPG Sbjct 350 DRAERALTPEEIVRIGDTYHAWLGCASAAAKGLTYHDVPGFCASASLDDIVAAGYTLTPG 409 Query 493 RYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRLR 540 RYVG PA EDDGEP++EK+ARL+ LL+A DESARLE VVR+QL RLR Sbjct 410 RYVGAPAGEDDGEPVEEKIARLTGDLLDALDESARLEGVVRQQLERLR 457 >gi|297562021|ref|YP_003680995.1| adenine-specific DNA-methyltransferase [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] gi|296846469|gb|ADH68489.1| Site-specific DNA-methyltransferase (adenine-specific) [Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111] Length=549 Score = 628 bits (1619), Expect = 1e-177, Method: Compositional matrix adjust. Identities = 320/538 (60%), Positives = 394/538 (74%), Gaps = 20/538 (3%) Query 16 KELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEG-MEES 74 K+LKDTLWKAADKLRGS+ A++YK +LGL+FLKYVSDA+ ERR I EL EG E+ Sbjct 16 KDLKDTLWKAADKLRGSMDAAEYKHFVLGLIFLKYVSDAFAERRVHIEKELREEGGYSET 75 Query 75 QIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMK 134 I + ++D E+Y GYGVF VP +ARW+ +AE K G +G+L+D+AM AV Sbjct 76 DIAETLEDREEYIGYGVFWVPQAARWEAIAERAKT-----GAGEDGVGKLLDDAMKAVAN 130 Query 135 ANPTLGGTLPR-LYNKDNIDQRRLGELIDLFNSARFSRQ----GEHR-ARDLMGEVYEYF 188 NP+L +LP+ L+N +D+RRLGEL+DL N F Q G R ARD++GEVYEY Sbjct 131 TNPSLRNSLPQGLFNARGVDERRLGELVDLINRIGFGDQLDPDGNRRSARDVLGEVYEYC 190 Query 189 LGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSG-RVYDPCCGSGGMFVQTEKFIYEHDG 247 LG FA AEG+RGGE++TP VV++IV +LEP G RVYDP CGSGGMFVQ EKF+ H G Sbjct 191 LGKFALAEGRRGGEYYTPACVVELIVAMLEPQKGERVYDPACGSGGMFVQAEKFVESHGG 250 Query 248 DPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLP 307 + +D+++YGQE + TWR+AKMNLAIHGI + LG +W DTF D HPD++ VMAN P Sbjct 251 NARDIAVYGQELNQNTWRLAKMNLAIHGI-SADLGTKWDDTFHNDHHPDLRAHVVMANPP 309 Query 308 FNIKDWA--RNEEDPRWRFGVPPANNANYAWIQHILYKLAP-GGRAGVVMANGSMSSNSN 364 FNI DW R DPRW++GVPP NANYAW+QH+ YKLAP GRAG+V+ANGSMSS + Sbjct 310 FNISDWGGDRLVMDPRWQWGVPPVGNANYAWLQHMAYKLAPKAGRAGIVLANGSMSSKQS 369 Query 365 GEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAA-GKQGSIDRCGQVLFI 423 GEGDIR +VE LV+CMVALP QLFRST IP C+W AKD+ A G +GSIDR GQVLFI Sbjct 370 GEGDIRRAMVEDGLVACMVALPGQLFRSTQIPACVWILAKDRGAKGGRGSIDRTGQVLFI 429 Query 424 DARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIK 483 DARELG++V R E+ LT +EI +I +TFHAW G+ SA G+ YED+ GFCKS +L EI+ Sbjct 430 DARELGEMVTRTEKQLTEDEIKQISNTFHAWLGTSSAKRNGLTYEDIGGFCKSVSLDEIR 489 Query 484 ATDYALTPGRYVGTPAVED--DGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 D+ LTPGRYVG VE+ D EP+DEK+ARL K L E FD SARLE VVREQLGR+ Sbjct 490 EHDFILTPGRYVGAAEVEEDPDAEPLDEKVARLQKELFEHFDASARLEAVVREQLGRV 547 >gi|307150615|ref|YP_003885999.1| adenine-specific DNA-methyltransferase [Cyanothece sp. PCC 7822] gi|306980843|gb|ADN12724.1| Site-specific DNA-methyltransferase (adenine-specific) [Cyanothece sp. PCC 7822] Length=526 Score = 556 bits (1433), Expect = 4e-156, Method: Compositional matrix adjust. Identities = 283/545 (52%), Positives = 362/545 (67%), Gaps = 35/545 (6%) Query 1 MPPRKKQAPQAPS-TMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERR 59 MP ++K A + +L+D LWKAADKLRG L A++YK V+LGL+FLKY+SDA+ E Sbjct 1 MPKKQKTETTASNGNTVKLEDKLWKAADKLRGHLDAAEYKHVVLGLIFLKYISDAFGELY 60 Query 60 EAIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAK 119 + + + A+ +D ++Y +F VPV ARW L K Sbjct 61 DKLSTDEYADP----------EDKDEYTAEHIFWVPVEARWSHLQAKAK---------TP 101 Query 120 NIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARD 179 +IG+ +DEAM+A+ K NP+L G LP+ Y K +D+R LGELIDL + ++R++D Sbjct 102 DIGKFVDEAMEAIEKENPSLKGVLPKDYGKPALDKRLLGELIDLIGTIGLG-DAQNRSQD 160 Query 180 LMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTE 239 ++G VYEYFLG FA AEGK+GG+F+TP VV+++V++LEP GRVYDPCCGSGGMFVQ+E Sbjct 161 ILGRVYEYFLGQFASAEGKKGGQFYTPRCVVELLVDMLEPYKGRVYDPCCGSGGMFVQSE 220 Query 240 KFIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQM 299 KF+ H G D+SIYGQES TW++ KMNLAI GID LGA+ +D+F D H +++ Sbjct 221 KFVEAHGGKIGDISIYGQESNPTTWKLCKMNLAIRGIDGN-LGAKNADSFRNDLHKELKA 279 Query 300 DYVMANLPFNIKDWARNE--EDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANG 357 DY++AN PFN+ DW ED RW +G PP NANYAWIQ I+ LAP G AG V+ANG Sbjct 280 DYILANPPFNVSDWGGQHLREDSRWIYGTPPVGNANYAWIQQIITHLAPNGIAGFVLANG 339 Query 358 SMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAA------GKQ 411 SMSSN +GEG+IR +VEADLV CMVALP QLF +T IP CLWF ++K K Sbjct 340 SMSSNQSGEGEIRKALVEADLVDCMVALPGQLFYNTQIPACLWFLTRNKGQSPLTLLNKG 399 Query 412 GSIDRCGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVP 471 G R G+ LFIDAR+LG L+DR R LT+EEI RI +T+H WRGS YEDVP Sbjct 400 GMRQRKGETLFIDARKLGVLIDRVHRELTSEEITRIAETYHNWRGSGKGE-----YEDVP 454 Query 472 GFCKSATLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERV 531 GFCKSA L +I+ Y LTPGRYVG V+DD EP +EKM RL+K L E F ESARLE Sbjct 455 GFCKSAALEDIRGHGYVLTPGRYVGAEEVDDDDEPFEEKMERLTKLLEEQFSESARLENE 514 Query 532 VREQL 536 + + L Sbjct 515 ICQNL 519 >gi|87300611|ref|ZP_01083453.1| type I restriction system adenine methylase [Synechococcus sp. WH 5701] gi|87284482|gb|EAQ76434.1| type I restriction system adenine methylase [Synechococcus sp. WH 5701] Length=603 Score = 555 bits (1430), Expect = 7e-156, Method: Compositional matrix adjust. Identities = 282/538 (53%), Positives = 358/538 (67%), Gaps = 25/538 (4%) Query 4 RKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIR 63 RK +A + + LW ADKLR ++ A++YK V+LGL+FLKY+SD+++E R + Sbjct 79 RKAKASGNGTANLGFEAKLWLTADKLRNNMDAAEYKHVVLGLIFLKYISDSFEEHRAKL- 137 Query 64 AELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQ 123 LA EG E + DP++Y+ VF VP ARW L N K IG+ Sbjct 138 --LAGEGDYEGANPE---DPDEYKAENVFWVPAEARWSHLQANAK---------QSTIGK 183 Query 124 LIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGE----HRARD 179 L+D+AM A+ + NP L G LP+ Y + +D++RLGELID+ + + E HR+ D Sbjct 184 LVDDAMVAIERDNPRLKGVLPKDYARPALDKQRLGELIDVIATIELTAASEGEQTHRSVD 243 Query 180 LMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTE 239 L+G VYEYFL FA AEGK GG+F+TP VV+ +VE+LEP GR+YDPCCGSGGMFVQ+E Sbjct 244 LLGRVYEYFLTRFASAEGKNGGQFYTPSCVVRCLVEMLEPYKGRIYDPCCGSGGMFVQSE 303 Query 240 KFIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQM 299 KF+ H G D+SIYGQES T R+A MNLA+ GI+ G +D+F RD HPD++ Sbjct 304 KFVESHGGKLGDISIYGQESNATTRRLAVMNLALRGIEAD-FGPEHADSFRRDLHPDLRA 362 Query 300 DYVMANLPFNIKDWARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSM 359 DYV+AN PFN DW R ++D RW+FGVPP NAN+AW+QH ++ LAP G AG V+ANGSM Sbjct 363 DYVLANPPFNDSDWFRKDDDVRWQFGVPPKGNANFAWVQHFIHHLAPQGMAGFVLANGSM 422 Query 360 SSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAA-GKQGSIDRCG 418 SSN +GEG+IR ++EADLV CMVALP QLF ST IPVCLWF AK KAA G++G DR G Sbjct 423 SSNQSGEGEIRKALIEADLVDCMVALPGQLFYSTQIPVCLWFLAKSKAADGQRGFRDRRG 482 Query 419 QVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSAT 478 LFIDAR+LG L+DR R L ++ +I T+H WR + YEDVPGFCKSAT Sbjct 483 HTLFIDARKLGTLIDRVHRELLEADLAKISSTYHRWRCTNGEG----SYEDVPGFCKSAT 538 Query 479 LAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 AEI A + LTPGRYVG VEDDGEP +EKM RL L F ESA+LE+ +R L Sbjct 539 TAEIAAHGHVLTPGRYVGAEEVEDDGEPFEEKMPRLVAELEAQFAESAKLEQAIRANL 596 >gi|253577074|ref|ZP_04854396.1| type I restriction-modification system DNA methylase [Paenibacillus sp. oral taxon 786 str. D14] gi|251843568|gb|EES71594.1| type I restriction-modification system DNA methylase [Paenibacillus sp. oral taxon 786 str. D14] Length=507 Score = 554 bits (1428), Expect = 1e-155, Method: Compositional matrix adjust. Identities = 281/522 (54%), Positives = 367/522 (71%), Gaps = 30/522 (5%) Query 18 LKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEESQIE 77 ++ LW ADKLRGS+ A++YK V+LGL+FLKYVSDA++E+ EA++ E A+ Sbjct 8 FEEKLWSMADKLRGSMDAAEYKHVVLGLLFLKYVSDAFEEKYEALKNEPYADP------- 60 Query 78 DLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANP 137 +D ++Y +F VP ARW + +N K KP IGQ ID AM A+ K NP Sbjct 61 ---EDRDEYVAENIFWVPKEARWSHIKDNAK-KP--------EIGQTIDNAMIAIEKENP 108 Query 138 TLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEG 197 +L G LP+ Y + +D+ RLGE+IDLF S + + E R++D++G VYEYFL FA AEG Sbjct 109 SLKGVLPKDYARPALDKTRLGEVIDLF-SFKVGDE-ESRSKDVLGRVYEYFLSKFASAEG 166 Query 198 KRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQ 257 K GGEF+TP SVV+++VE+++P GRVYDPCCGSGGMFVQ+EKF+ EH G D++IYGQ Sbjct 167 KNGGEFYTPNSVVRLLVEMIQPFKGRVYDPCCGSGGMFVQSEKFVEEHQGRIGDIAIYGQ 226 Query 258 ESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKDWA--R 315 ES TW++ KMNLAI GID LG +DTF D H +++ DY++AN PFNI DW R Sbjct 227 ESNPTTWKLCKMNLAIRGIDGN-LGEHHADTFHNDLHKNLKADYILANPPFNISDWGGER 285 Query 316 NEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVE 375 ED RW +GVPPA NANYAWIQHI+ KLAP G AG V+ANGSMS+++ E +IR+++V Sbjct 286 LTEDARWTYGVPPAGNANYAWIQHIVNKLAPSGVAGFVLANGSMSTSTTAEFEIRSKLVN 345 Query 376 ADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLVDRA 435 ADLV C+V LP QLF ST IPVCLWF AK+KA +G DR G++LFIDAR++G +VDR Sbjct 346 ADLVDCIVTLPGQLFYSTQIPVCLWFIAKNKAP--KGFRDRRGEILFIDARKMGHMVDRT 403 Query 436 ERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPGRYV 495 R L+ E+I +I DT+HAWRG A YEDV GFCK+A LAE++ +Y LTPGRYV Sbjct 404 HRELSTEDIRKIADTYHAWRGQAEAGT----YEDVKGFCKAAELAEVQEHEYILTPGRYV 459 Query 496 GTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLG 537 G VE+D EP ++KMARL+ L E F +S +LE +R++LG Sbjct 460 GIEDVEEDSEPFEDKMARLTAELGEQFAKSRQLEDEIRKRLG 501 >gi|291288454|ref|YP_003505270.1| adenine-specific DNA-methyltransferase [Denitrovibrio acetiphilus DSM 12809] gi|290885614|gb|ADD69314.1| Site-specific DNA-methyltransferase (adenine- specific) [Denitrovibrio acetiphilus DSM 12809] Length=525 Score = 554 bits (1427), Expect = 2e-155, Method: Compositional matrix adjust. Identities = 278/538 (52%), Positives = 360/538 (67%), Gaps = 28/538 (5%) Query 8 APQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELA 67 A Q S +D LW+ ADKLRG++ AS+YK V+LGL+FLKY+SD++ + + + A Sbjct 2 AKQNGSANIGFEDKLWQTADKLRGNMDASEYKHVVLGLIFLKYISDSFQAKYDELLA--- 58 Query 68 AEGMEESQIEDLID--DPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLI 125 +Q D D D ++Y VF VP ARW+ L K IG+++ Sbjct 59 ------TQETDYTDPEDRDEYMSDNVFWVPAEARWESLIAKAK---------TPEIGKVL 103 Query 126 DEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVY 185 D+AM A+ K N TL LP+ Y++ ID+ RLGEL+D+ S + + ++DL+G VY Sbjct 104 DDAMIAIEKENKTLKNILPKTYSRPEIDKSRLGELLDIIGSIPLIDKAQ-SSKDLLGRVY 162 Query 186 EYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEH 245 EYF+G FA EG+ GGEF+TP SVV+++VE++EP GRVYDPCCGSGGMFVQ+EKF EH Sbjct 163 EYFIGMFASKEGRSGGEFYTPQSVVQLLVEMIEPYKGRVYDPCCGSGGMFVQSEKFAEEH 222 Query 246 DGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMAN 305 G +D+S+YGQE TWR+AKMNLAI GI+ LGA W+DTF D H D++ D+++AN Sbjct 223 GGRLRDISVYGQEYNATTWRLAKMNLAIRGIE-ANLGAEWADTFTNDLHKDLKSDFILAN 281 Query 306 LPFNIKDWARN--EEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNS 363 PFN+ DW N + D RW++G PP NNANYAWIQH ++ LAP G AG V+ANGSMSSN+ Sbjct 282 PPFNMSDWGGNKLKNDVRWKYGTPPDNNANYAWIQHFIHHLAPNGVAGFVLANGSMSSNT 341 Query 364 NGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFI 423 +GEG+IR I+EADLV CM+ALP QLF +T IPVCLWF A++K GK G +R G+ LFI Sbjct 342 SGEGEIRKNIIEADLVDCMIALPGQLFYTTQIPVCLWFLARNK--GKNGHRERKGETLFI 399 Query 424 DARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKS--AAVKGIMYEDVPGFCKSATLAE 481 DAR++G L DR R L E+I +I T+HAWR + A+ YEDV GFCKS TL Sbjct 400 DARKMGRLEDRVHRVLVPEDIQKIASTYHAWRSNPDVIASEGKQSYEDVAGFCKSVTLDT 459 Query 482 IKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 IK DY LTPGRYVG VEDDGEP DEKM RLS L E +L+ V++E L +L Sbjct 460 IKEHDYVLTPGRYVGAEEVEDDGEPFDEKMKRLSTQLYSQMTEGEKLDAVIKENLAKL 517 >gi|256833459|ref|YP_003162186.1| N-6 DNA methylase [Jonesia denitrificans DSM 20603] gi|256686990|gb|ACV09883.1| N-6 DNA methylase [Jonesia denitrificans DSM 20603] Length=521 Score = 553 bits (1425), Expect = 3e-155, Method: Compositional matrix adjust. Identities = 276/528 (53%), Positives = 364/528 (69%), Gaps = 21/528 (3%) Query 12 PSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGM 71 P K L+ TLW+AADKLRG+ S+YK V+LGLVFLKY+SD ++ERR + AELAAEG+ Sbjct 7 PKPTKTLEQTLWEAADKLRGNQEPSEYKHVVLGLVFLKYISDRFEERRATLEAELAAEGI 66 Query 72 EESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDA 131 + ++ D ++D ++Y + VF VP ARW ++ +V +P IGQ ID+AMD Sbjct 67 KPERLPDFLEDRDEYTSHNVFWVPELARWGYIQ-------SVAKQP--EIGQQIDQAMDL 117 Query 132 VMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGN 191 + K NPTL G LPR Y +D +D+RRLGEL+DL S F+ +H A D++G VYEYFLG Sbjct 118 IEKENPTLRGVLPRNYGRDGLDKRRLGELVDLIGSIGFTETDDHGADDVLGRVYEYFLGQ 177 Query 192 FARAE-GKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPK 250 FA E GK G F+TP SVVK +VE+LEP GRVYDP GSGGMFVQ+ +F+ H G Sbjct 178 FAGKETGKDAGAFYTPRSVVKTLVEMLEPYQGRVYDPAAGSGGMFVQSAEFVKAHGGKRT 237 Query 251 DVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNI 310 D+S+YGQE + TW+++KMNLA+ GI+ +G R +D+F D HPD++ D+V+AN PFN+ Sbjct 238 DISVYGQEFTDTTWKLSKMNLALRGIEAD-MGPRSADSFTDDLHPDLRADFVIANPPFNV 296 Query 311 KDW--ARNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGD 368 DW A+ E DPRW++G PP NAN+AW+QH +Y L+P G AG V+ANGS+SS S GEG+ Sbjct 297 SDWWDAKLEGDPRWQYGTPPQGNANFAWVQHFIYHLSPKGTAGFVLANGSLSSKSGGEGE 356 Query 369 IRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDAREL 428 +R ++VEADLV C+VA+P +LF +TGIPV LWF + KA G +R +VLFIDAR+L Sbjct 357 MRRKLVEADLVDCIVAMPDKLFFNTGIPVALWFVS--KARHGNGHRERRSEVLFIDARKL 414 Query 429 GDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYA 488 G + R R LT+++I +I DT+HAWR YEDVPGF K+A+L EI DY Sbjct 415 GTMESRRLRVLTDDDIAKIADTYHAWRNHDGG------YEDVPGFAKAASLEEIAKHDYV 468 Query 489 LTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 LTPGRYVG E D EPIDEK+ RL+K L F+ LE VR++L Sbjct 469 LTPGRYVGAAEAEVDDEPIDEKIERLTKELFAEFERGRELEDEVRQRL 516 >gi|253576200|ref|ZP_04853531.1| type I restriction-modification system DNA methylase [Paenibacillus sp. oral taxon 786 str. D14] gi|251844327|gb|EES72344.1| type I restriction-modification system DNA methylase [Paenibacillus sp. oral taxon 786 str. D14] Length=507 Score = 550 bits (1417), Expect = 2e-154, Method: Compositional matrix adjust. Identities = 277/522 (54%), Positives = 367/522 (71%), Gaps = 30/522 (5%) Query 18 LKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEESQIE 77 ++ LW ADKLRGS+ A++YK V LGL+FLKYVSDA++E+ EA++ E A+ Sbjct 8 FEEKLWSMADKLRGSMDAAEYKHVALGLLFLKYVSDAFEEKYEALKNEPYADP------- 60 Query 78 DLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANP 137 +D ++Y +F VP ARW + +N K KP IGQ+ID AM A+ K NP Sbjct 61 ---EDRDEYVAENIFWVPKEARWSHIKDNAK-KP--------EIGQIIDNAMIAIEKENP 108 Query 138 TLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEG 197 +L G LP+ Y + +D+ RLGE+IDLF S + + E R++D++G VYEYFL FA AEG Sbjct 109 SLKGVLPKDYARPALDKTRLGEVIDLF-SFKVGDE-ESRSKDVLGRVYEYFLSKFASAEG 166 Query 198 KRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQ 257 K GGEF+TP SVV+++VE+++P GRVYDPCCGSGGMFVQ+EKF+ EH G D+++YGQ Sbjct 167 KNGGEFYTPNSVVRLLVEMIQPFKGRVYDPCCGSGGMFVQSEKFVEEHQGRIGDIAVYGQ 226 Query 258 ESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKDWA--R 315 ES TW++ KMNLAI GID LG +DTF D H +++ DY++AN PFNI DW R Sbjct 227 ESNPTTWKLCKMNLAIRGIDGN-LGEHHADTFHNDLHKNLKADYILANPPFNISDWGGER 285 Query 316 NEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVE 375 +D RW +GVPPA NANYAWIQHI+ KLAP G AG V+ANGSMS+++ E +IR+++V Sbjct 286 LTDDTRWTYGVPPAGNANYAWIQHIVNKLAPSGVAGFVLANGSMSTSTTAEFEIRSKLVN 345 Query 376 ADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLVDRA 435 ADLV C+V LP QLF ST IPVCLWF AK+KA +G DR G++LFIDAR++G +VDR Sbjct 346 ADLVDCIVTLPGQLFYSTQIPVCLWFIAKNKAP--KGFRDRRGEILFIDARKMGHMVDRT 403 Query 436 ERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPGRYV 495 R L+ E+I +I DT+HAWRG YEDV GFCK+A LA+++ +Y LTPGRYV Sbjct 404 HRELSTEDIRKIADTYHAWRGQAEVGA----YEDVKGFCKAAKLADVQEHEYILTPGRYV 459 Query 496 GTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLG 537 G VE+D EP ++KMARL++ L E F +S +LE +R++LG Sbjct 460 GIEDVEEDSEPFEDKMARLTEELAEQFAKSRQLEDEIRKRLG 501 >gi|71275992|ref|ZP_00652274.1| N-6 DNA methylase:Type I restriction-modification system, M subunit [Xylella fastidiosa Dixon] gi|71899062|ref|ZP_00681227.1| N-6 DNA methylase:Type I restriction-modification system, M subunit [Xylella fastidiosa Ann-1] gi|71163225|gb|EAO12945.1| N-6 DNA methylase:Type I restriction-modification system, M subunit [Xylella fastidiosa Dixon] gi|71731175|gb|EAO33241.1| N-6 DNA methylase:Type I restriction-modification system, M subunit [Xylella fastidiosa Ann-1] Length=524 Score = 548 bits (1411), Expect = 1e-153, Method: Compositional matrix adjust. Identities = 287/540 (54%), Positives = 359/540 (67%), Gaps = 32/540 (5%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 M RK + L+KAADKLRG++ S YK V LGL+FLKY+SDA+ E Sbjct 1 MAHRKTTTKNGNGGTLGFEAELFKAADKLRGNMEPSDYKHVALGLIFLKYISDAF----E 56 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 A +EL AE + ++ D ++Y + VF VP ARW L N K Sbjct 57 AKHSELLAEDPQAAE------DKDEYLAHNVFWVPKQARWSHLKANAK---------QST 101 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IG LIDEAM + K NP+L LP+ Y + +++ LGELIDL + + +G R++D+ Sbjct 102 IGTLIDEAMRDIEKDNPSLKHVLPKDYARPALNKVMLGELIDLISGIALNEEGA-RSKDI 160 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 +G VYEYFLG FA AEGKRGGEF+TP SVV+V+V++LEP SGRVYDPCCGSGGMFVQ+EK Sbjct 161 LGRVYEYFLGQFAGAEGKRGGEFYTPRSVVRVLVQMLEPYSGRVYDPCCGSGGMFVQSEK 220 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSD--TFARDQHPDVQ 298 F+ EH G D++IYGQES TWR+AKMNLA+ GID+ RW++ +F D D++ Sbjct 221 FVLEHGGRIGDIAIYGQESNYTTWRLAKMNLAVRGIDSD---IRWNNEGSFHNDALRDLK 277 Query 299 MDYVMANLPFNIKDWA--RNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMAN 356 DY++AN PFNI DW R ED RW+FGVPPA NANYAW+QHI + LAP G AGVV+AN Sbjct 278 ADYILANPPFNISDWGGDRLREDVRWKFGVPPAGNANYAWLQHIYHHLAPNGTAGVVLAN 337 Query 357 GSMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDR 416 GSMSSN +GEG+IR ++EAD+V CMVA+P QLF ST IP CLWF A++K GK G DR Sbjct 338 GSMSSNHSGEGEIRTHMIEADIVDCMVAMPGQLFYSTQIPACLWFLARNKNPGK-GLRDR 396 Query 417 CGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKS 476 GQVL +DAR LG LVDR R LT+E+I +I DT+HAWRG + AA Y DV GFCKS Sbjct 397 RGQVLLMDARALGVLVDRTRRELTDEQIQKIADTYHAWRGEQGAAD----YADVAGFCKS 452 Query 477 ATLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 ATL +I+ Y LTPGRYVG D E +E+M RL+ L E ESA + +REQL Sbjct 453 ATLEDIRKHGYVLTPGRYVGIKGFVKDNESFEERMTRLTTELGEQLAESATFQTTMREQL 512 >gi|88604024|ref|YP_504202.1| N-6 DNA methylase [Methanospirillum hungatei JF-1] gi|88189486|gb|ABD42483.1| N-6 DNA methylase [Methanospirillum hungatei JF-1] Length=532 Score = 547 bits (1409), Expect = 2e-153, Method: Compositional matrix adjust. Identities = 272/543 (51%), Positives = 371/543 (69%), Gaps = 24/543 (4%) Query 4 RKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIR 63 R K+ + + + TLW AADKLR ++ A++YK V+LGL+FLKY+SDA++E+ ++ Sbjct 3 RAKKTKETTAANLGFEATLWAAADKLRNNMDAAEYKHVVLGLIFLKYLSDAFEEKHSSLE 62 Query 64 AELAAEG----MEESQIE-DLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPA 118 + + E ++ +I+DP++Y+ +F +P ARW ++ +N K +P Sbjct 63 QAYSDPQSTWYIAEPEVRYGVIEDPDEYRSENIFWIPKEARWSYIQQNAK-RP------- 114 Query 119 KNIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRAR 178 IG+++D+AM A+ + N L LP+ Y + +D+ +LGELIDL + S E+R++ Sbjct 115 -EIGKIVDDAMYAIERDNAVLKNILPKEYARPGLDKEKLGELIDLIGTLNLS-DSENRSK 172 Query 179 DLMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQT 238 D++G VYEYFL FA AEGK GG+F+TP VV+ +V ++ P GRVYDPCCGSGGMFVQ+ Sbjct 173 DIIGRVYEYFLSEFASAEGKNGGQFYTPRCVVQTLVAMISPFKGRVYDPCCGSGGMFVQS 232 Query 239 EKFIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQ 298 EKF+ H G D+SIYGQES TW++AKMNLAI GID+ LGA +D+F RD H ++ Sbjct 233 EKFVEAHGGRIGDISIYGQESNPTTWKLAKMNLAIRGIDHD-LGAEHADSFRRDLHATLK 291 Query 299 MDYVMANLPFNIKDWARN--EEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMAN 356 DY++AN PFN+KDW ++D RWR+G+PP NANYAWIQH ++ L+P G AG V+AN Sbjct 292 ADYILANPPFNMKDWGGENLKDDVRWRYGIPPTGNANYAWIQHFIHHLSPSGIAGFVLAN 351 Query 357 GSMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDR 416 GSMSSN +GEG+IR ++EADLV CMVALP QLF ST IP CLWF A++++ G+ DR Sbjct 352 GSMSSNQSGEGEIRKNLLEADLVDCMVALPGQLFYSTQIPACLWFVARNRSNGR--FRDR 409 Query 417 CGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKS 476 G+VLFIDAR++G + DR R LT+E+I RI T+HAWRG SA YEDVPGFC S Sbjct 410 RGEVLFIDARKMGVMRDRTHRELTDEDIERIAGTYHAWRGDASAG----EYEDVPGFCAS 465 Query 477 ATLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 ATL EI + LTPGRYVG EDDGEP EKM RL+K L E ++ ARL+ +++ L Sbjct 466 ATLEEIAKHGHVLTPGRYVGAEDAEDDGEPFAEKMTRLTKQLSEQMEDGARLDEEIKKNL 525 Query 537 GRL 539 G L Sbjct 526 GGL 528 >gi|205372127|ref|ZP_03224943.1| type I restriction-modification system DNA methylase [Bacillus coahuilensis m4-4] Length=506 Score = 543 bits (1400), Expect = 2e-152, Method: Compositional matrix adjust. Identities = 274/522 (53%), Positives = 361/522 (70%), Gaps = 31/522 (5%) Query 18 LKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEESQIE 77 ++ LW ADKLRGS+ + +YK+V+LGL+FLKYVSDA++ER AEL A+ +S+ Sbjct 8 FEEQLWSMADKLRGSMDSGEYKNVVLGLLFLKYVSDAFEERH----AELEADEYADSE-- 61 Query 78 DLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANP 137 D ++Y +F VP ARW ++ +N K KP IGQ+ID+AM A+ K N Sbjct 62 ----DRDEYVMDNIFWVPKEARWSYIKDNAK-KP--------EIGQIIDKAMIAIEKENA 108 Query 138 TLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEG 197 +L G LP+ Y + +D+ RLGE IDLF S + + E R++D++G VYEYFL FA AEG Sbjct 109 SLQGVLPKDYARPALDKVRLGETIDLF-SFKVGDE-ESRSKDVLGRVYEYFLSKFASAEG 166 Query 198 KRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQ 257 K GGEF+TP SVV+++VE+LEP GR+YDPCCGSGGMFVQ+EKF+ EH G D+++YGQ Sbjct 167 KNGGEFYTPSSVVRLLVEMLEPYKGRIYDPCCGSGGMFVQSEKFVEEHQGKLGDIAVYGQ 226 Query 258 ESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKDWARNE 317 ES TW++ KMNLAI GID +G +DTF D H ++ DY++AN PFNIKDW ++ Sbjct 227 ESNPTTWKLCKMNLAIRGIDGN-IGTHNADTFHNDLHKGLKADYILANPPFNIKDWGGDK 285 Query 318 --EDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVE 375 ED RW++G PP NANYAWIQH++ KLAP G AG V+ANGSMSSN++GEG+IR ++E Sbjct 286 LREDVRWQYGTPPTGNANYAWIQHMISKLAPAGTAGFVLANGSMSSNTSGEGEIRKNLIE 345 Query 376 ADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLVDRA 435 ADLV C+V LP QLF ST IPVC+WF +K+K+ K G R G++LFIDAR+LG +VDR Sbjct 346 ADLVECIVTLPGQLFYSTQIPVCIWFVSKNKS--KTGKRTRNGEILFIDARKLGFMVDRT 403 Query 436 ERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPGRYV 495 + T+ +I +I FH WRG+ A YEDV GFCK+A L E++ DY LTPGRYV Sbjct 404 HKEFTDVDIEKITKAFHTWRGTLGEA-----YEDVQGFCKAAMLEEVRNNDYILTPGRYV 458 Query 496 GTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLG 537 G VEDD EP + K+ RL+ L E F++S LE +R LG Sbjct 459 GLEEVEDDTEPFEAKIVRLTTELSEQFEKSKELEDQIRRALG 500 >gi|87310398|ref|ZP_01092528.1| type I restriction system adenine methylase [Blastopirellula marina DSM 3645] gi|87286897|gb|EAQ78801.1| type I restriction system adenine methylase [Blastopirellula marina DSM 3645] Length=526 Score = 543 bits (1399), Expect = 3e-152, Method: Compositional matrix adjust. Identities = 273/522 (53%), Positives = 363/522 (70%), Gaps = 22/522 (4%) Query 18 LKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEESQIE 77 + LW AADK+R ++ A++YK V+LGL+FLKY+SDA++E R+ + LA EG Sbjct 19 FESKLWLAADKMRNNMDAAEYKHVVLGLIFLKYISDAFEEMRQKL---LAGEGDYAGADP 75 Query 78 DLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANP 137 + +P++Y+ F VP +ARW+ L +N K +P IG+LID+AM A+ + NP Sbjct 76 E---EPDEYRAENCFWVPTAARWQLLQDNAK-------QP--TIGKLIDDAMVAIERDNP 123 Query 138 TLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEG 197 L G LP+ + + +D++RLGELIDL + E+R++D++G VYEYFL FA AEG Sbjct 124 RLKGVLPKDFARPALDKQRLGELIDLIGTIGLG-DAENRSKDILGRVYEYFLSEFASAEG 182 Query 198 KRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQ 257 K+GG+F+TP VV+V+VE+L P GR+YDPCCGS GMFVQ+EKF+ EH G D+++YGQ Sbjct 183 KKGGQFYTPRCVVRVLVEMLAPGKGRIYDPCCGSAGMFVQSEKFVEEHGGRIGDIAVYGQ 242 Query 258 ESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKDWARNE 317 ES T R+A MNLAI GI+ +G +DTF RD H D++ D+V+AN PFN DW RN+ Sbjct 243 ESNPTTRRLALMNLAIRGIEGD-IGPENADTFRRDLHKDLKADFVLANPPFNDSDWHRND 301 Query 318 EDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVEAD 377 +D RW +GVPP NANYAW+QH ++ LAPGG AG V+ANGSMSSN +GEG+IR IVEAD Sbjct 302 DDVRWAYGVPPKGNANYAWVQHFIHHLAPGGFAGFVLANGSMSSNQSGEGEIRKAIVEAD 361 Query 378 LVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLVDRAER 437 LV CMVALP QLF ST IPVCLWF + K + +R G+ LFIDAR+LG L+DR R Sbjct 362 LVDCMVALPGQLFYSTQIPVCLWFLTRGKK--DKSRRNRVGETLFIDARKLGVLIDRVHR 419 Query 438 ALTNEEIVRIGDTFHAWRGS-KSAAVKGIM--YEDVPGFCKSATLAEIKATDYALTPGRY 494 LT+EE+ RI DT+HAWRG K+ K + YED+PGFC SA +I Y LTPGRY Sbjct 420 ELTDEELQRIADTYHAWRGDLKTINPKSKLKKYEDIPGFCFSAKKEQIAEHGYVLTPGRY 479 Query 495 VGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 VG VE+D EP +EKMARL++ L + F ES +LE+ +++ L Sbjct 480 VGAEEVEEDDEPFEEKMARLTQQLTDQFAESKKLEKAIQKNL 521 >gi|334702404|ref|ZP_08518270.1| type I restriction system adenine methylase [Aeromonas caviae Ae398] Length=518 Score = 543 bits (1398), Expect = 4e-152, Method: Compositional matrix adjust. Identities = 282/522 (55%), Positives = 357/522 (69%), Gaps = 32/522 (6%) Query 22 LWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEESQIEDLID 81 L+KAADKLRG++ S YK V LGL+FLKY+SDA++ + +A+ AE A + Sbjct 21 LFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEAKHKALLAEDAQAA----------E 70 Query 82 DPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANPTLGG 141 D ++Y VF VP ARW L N K IG LID+AM A+ K N +L G Sbjct 71 DKDEYLADNVFWVPKEARWSHLQANAK---------LPTIGTLIDDAMRAIEKDNESLKG 121 Query 142 TLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEGKRGG 201 LP+ Y + +++ LGELIDL + + +G+ R++D++G VYEYFLG FA AEGKRGG Sbjct 122 VLPKDYARPALNKVMLGELIDLISGIALNEEGD-RSKDILGRVYEYFLGQFAGAEGKRGG 180 Query 202 EFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQESIE 261 EF+TP SVV+V+VE+LEP SGRVYDPCCGSGGMFVQ+EKF+ EH G D++IYGQES Sbjct 181 EFYTPRSVVRVLVEMLEPYSGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNY 240 Query 262 ETWRMAKMNLAIHGIDNKGLGARWSD--TFARDQHPDVQMDYVMANLPFNIKDWA--RNE 317 TWR+AKMNLA+ GID+ RW++ +F +D+ D++ DY++AN PFNI DW R Sbjct 241 TTWRLAKMNLAVRGIDSD---IRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLR 297 Query 318 EDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVEAD 377 +D RW+FG PP NANYAW+QHI + LAP G AGVV+ANGSMSSN +GEG+IR ++EAD Sbjct 298 DDVRWKFGAPPVGNANYAWLQHIYHHLAPNGTAGVVLANGSMSSNQSGEGEIRKAMLEAD 357 Query 378 LVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLVDRAER 437 V CMVALP QLF ST IP CLWF A++K GK G DR GQVLFIDAR+LG LVDR R Sbjct 358 AVDCMVALPGQLFYSTQIPACLWFLARNKNPGK-GLRDRRGQVLFIDARKLGVLVDRTRR 416 Query 438 ALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPGRYVGT 497 LT+EE+ +I DT+HAWRG A Y DV GFCKSA++ +I+ + LTPGRYVG Sbjct 417 ELTDEEVQKIADTYHAWRGEDGAGD----YADVAGFCKSASMDDIRKHGHVLTPGRYVGA 472 Query 498 PAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 EDDGEP +EKM RLS A E E+ +L+ + L L Sbjct 473 AEQEDDGEPFEEKMLRLSAAWREQRAEAVKLDAAIEANLKEL 514 >gi|206603733|gb|EDZ40213.1| N-6 DNA methylase [Leptospirillum sp. Group II '5-way CG'] Length=524 Score = 543 bits (1398), Expect = 4e-152, Method: Compositional matrix adjust. Identities = 273/528 (52%), Positives = 355/528 (68%), Gaps = 30/528 (5%) Query 18 LKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEESQIE 77 L+ LW+AADKLR ++ A++YK V+LGL+FLKYVSD+++E + E+ E Sbjct 17 LETKLWQAADKLRNNMDAAEYKHVVLGLLFLKYVSDSFEEHHAKLTGEMDQGANPE---- 72 Query 78 DLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANP 137 DP++Y+ VF VP ARW L N K +P IG++ID+AM A+ + N Sbjct 73 ----DPDEYRADNVFWVPKEARWSVLQANAK-RP--------EIGKVIDDAMVAIERDNT 119 Query 138 TLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEG 197 +L LP+ + + +D++RLGELIDL + + EHR+RD++G VYEYFL FA AEG Sbjct 120 SLKAVLPKDFARPGLDKQRLGELIDLVGTIGLGDK-EHRSRDMLGRVYEYFLSQFASAEG 178 Query 198 KRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQ 257 K+GG+F+TP SVV+V+VE+L P GRVYDPCCGSGGMFVQ+EKFI H G D+SIYGQ Sbjct 179 KKGGQFYTPRSVVRVLVEMLAPYKGRVYDPCCGSGGMFVQSEKFIEVHGGRIGDISIYGQ 238 Query 258 ESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKDWA--R 315 ES TW++A MNLAI GI LG +D+F RD HPD++ DY++AN PFN DW R Sbjct 239 ESNHTTWKLAAMNLAIRGI-AANLGKENADSFHRDLHPDLKADYILANPPFNSSDWGGDR 297 Query 316 NEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVE 375 ED RW +GVPP NAN+AW+QH + LAP G AG V+ANGS+SSN +GEG+IR +VE Sbjct 298 LREDRRWVYGVPPVGNANFAWVQHFISHLAPNGVAGFVLANGSLSSNQSGEGEIRKNMVE 357 Query 376 ADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGK----QGSIDRCGQVLFIDARELGDL 431 D+V C+VALP QLF ST IPV LWF +++K GK DR G++LFIDAR+LG + Sbjct 358 GDIVDCIVALPGQLFYSTQIPVSLWFVSRNKKNGKGQEGHALRDRSGEILFIDARKLGFM 417 Query 432 VDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTP 491 DR R L++E+I +I T+H WRG YED+PGFCK A+L E++ + LTP Sbjct 418 ADRTHRDLSDEDIAKIAGTYHHWRGDGDG-----QYEDIPGFCKKASLEEVRTHGHVLTP 472 Query 492 GRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 GRYVG VEDDGEP +EKM RL+ L E F ESARLE +R L +L Sbjct 473 GRYVGAEEVEDDGEPFEEKMKRLTTQLDEQFKESARLEAEIRSNLSKL 520 >gi|15839331|ref|NP_300019.1| type I restriction-modification system DNA methylase [Xylella fastidiosa 9a5c] gi|9107980|gb|AAF85527.1|AE004080_9 type I restriction-modification system DNA methylase [Xylella fastidiosa 9a5c] Length=519 Score = 542 bits (1396), Expect = 6e-152, Method: Compositional matrix adjust. Identities = 280/519 (54%), Positives = 348/519 (68%), Gaps = 32/519 (6%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 M RK + L+KAADKLRG++ S YK V LGL+FLKY+SDA++ + Sbjct 1 MAHRKTTTKNGNGGTLGFEAELFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEAKHS 60 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 A+ AE A +D ++Y + VF VP ARW L N K Sbjct 61 ALLAEDAQAA----------EDKDEYLAHNVFWVPKQARWSHLKANAK---------QST 101 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IG LIDEAM + K NP+L LP+ Y + +++ LGELIDL + + +G R++D+ Sbjct 102 IGTLIDEAMRDIEKDNPSLKHVLPKDYARPALNKVMLGELIDLISGIALNEEGA-RSKDI 160 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 +G VYEYFLG FA AEGKRGGEF+TP SVV+V+V++LEP SGRVYDPCCGSGGMFVQ+EK Sbjct 161 LGRVYEYFLGQFAGAEGKRGGEFYTPRSVVRVLVQMLEPYSGRVYDPCCGSGGMFVQSEK 220 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSD--TFARDQHPDVQ 298 F+ EH G D++IYGQES TWR+AKMNLA+ GID+ RW++ +F D D++ Sbjct 221 FVLEHGGRIGDIAIYGQESNYTTWRLAKMNLAVRGIDSD---IRWNNEGSFHNDALRDLK 277 Query 299 MDYVMANLPFNIKDWA--RNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMAN 356 DY++AN PFNI DW R ED RW+FGVPPA NANYAW+QHI + LAP G AGVV+AN Sbjct 278 ADYILANPPFNISDWGGDRLREDVRWKFGVPPAGNANYAWLQHIYHHLAPNGTAGVVLAN 337 Query 357 GSMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDR 416 GSMSSN +GEG+IR ++EAD+V CM+A+P QLF ST IP CLWF A++K GK G DR Sbjct 338 GSMSSNHSGEGEIRTHMIEADIVDCMIAMPGQLFYSTQIPACLWFLARNKNPGK-GLRDR 396 Query 417 CGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKS 476 GQVL +DAR LG LVDR R LT+E I +I DT+HAWRG + AA Y DV GFCKS Sbjct 397 RGQVLLMDARALGVLVDRTRRELTDEHIQQIADTYHAWRGEQGAAA----YADVAGFCKS 452 Query 477 ATLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLS 515 ATL +I+ Y LTPGRYVG EDDGEP +KM RLS Sbjct 453 ATLEDIRKQGYVLTPGRYVGAVEREDDGEPFPQKMQRLS 491 >gi|251771139|gb|EES51722.1| N-6 DNA methylase [Leptospirillum ferrodiazotrophum] Length=525 Score = 541 bits (1395), Expect = 8e-152, Method: Compositional matrix adjust. Identities = 273/525 (52%), Positives = 360/525 (69%), Gaps = 31/525 (5%) Query 22 LWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE-AIRAELAAEGMEESQIEDLI 80 LW+AADKLR ++ A++YK V+LGL+FLKYVSDA++E + I E+AAE E Sbjct 21 LWQAADKLRNNMDAAEYKHVVLGLIFLKYVSDAFEEFHDRLISTEIAAEADPE------- 73 Query 81 DDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANPTLG 140 DP++Y+ +F VP ARW L + K +P IG++ID+AM A+ + N +L Sbjct 74 -DPDEYRAENIFWVPPEARWSTLQAHAK-RP--------EIGKIIDDAMVAIERENKSLK 123 Query 141 GTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEGKRG 200 LP+ Y + ++D++RLGEL+DL + Q +HR++D++G VYEYFL FA AEGKRG Sbjct 124 AILPKDYARTSLDKQRLGELVDLVGTIGLG-QKDHRSKDILGRVYEYFLSQFASAEGKRG 182 Query 201 GEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQESI 260 G+F+TP SVV V+VE+L P GRV+DPCCGSGGMFVQ+EKFI H G D+SIYGQES Sbjct 183 GQFYTPRSVVSVLVEMLAPYKGRVFDPCCGSGGMFVQSEKFIEAHGGRIGDISIYGQESN 242 Query 261 EETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKDWA--RNEE 318 TW++A MNLA+ GI+ LG D+F RD HPD++ DY++AN PFN DW R E Sbjct 243 NTTWKLAAMNLALRGIE-ANLGKENDDSFHRDLHPDLKADYILANPPFNSSDWGGERLRE 301 Query 319 DPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVEADL 378 D RW +GVPP NANYAW+Q+ +Y LAP G AG V+ANGS+SSN + EG+IR +VEAD+ Sbjct 302 DKRWVYGVPPTGNANYAWVQNFIYHLAPNGVAGFVLANGSLSSNQSNEGEIRKSMVEADI 361 Query 379 VSCMVALPTQLFRSTGIPVCLWFFAKDKAAGK----QGSIDRCGQVLFIDARELGDLVDR 434 V C+VA+P QLF ST IPV LWF +++K GK + DR G++LFIDAR+LG + DR Sbjct 362 VDCIVAMPGQLFYSTQIPVSLWFVSRNKKNGKGVEGRPLRDRSGEILFIDARKLGFMSDR 421 Query 435 AERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPGRY 494 R L+ +++ RI DT+H WRG + YEDV GFCKSA L E+++ + LTPGRY Sbjct 422 THRDLSVDDLARITDTYHNWRGDGTGT-----YEDVQGFCKSAKLEEVRSHGHVLTPGRY 476 Query 495 VGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 VG +EDDGEP +EKM RL+ L E F ESARLE +R L +L Sbjct 477 VGAEEIEDDGEPFEEKMKRLTTQLNEQFKESARLEAEIRSNLSKL 521 >gi|94986116|ref|YP_605480.1| N-6 DNA methylase [Deinococcus geothermalis DSM 11300] gi|94556397|gb|ABF46311.1| Type I restriction-modification system DNA methylase [Deinococcus geothermalis DSM 11300] Length=517 Score = 540 bits (1391), Expect = 2e-151, Method: Compositional matrix adjust. Identities = 284/500 (57%), Positives = 349/500 (70%), Gaps = 36/500 (7%) Query 22 LWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAE--LAAEGMEESQIEDL 79 L+KAADKLRG++ S YK V LGL+FLKY+SDA++ R +A+ AE AAE Sbjct 20 LFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHQALLAEDPRAAE---------- 69 Query 80 IDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANPTL 139 D ++Y VF VP ARW L N + +P IG LIDEAM A+ K N +L Sbjct 70 --DRDEYLADNVFWVPKEARWSHLRANAR-RP--------EIGLLIDEAMRAIEKENESL 118 Query 140 GGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEGKR 199 G LP+ Y + +++ LGELIDL + +G+ R++D++G VYEYFLG FA AEGKR Sbjct 119 KGVLPKDYARPALNKVMLGELIDLISGIALGEEGD-RSKDILGRVYEYFLGQFAGAEGKR 177 Query 200 GGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQES 259 GGEF+TP SVV+V+VE+LEP GRVYDPCCGSGGMFVQ+EKF+ EH G D++IYGQES Sbjct 178 GGEFYTPRSVVRVLVEMLEPYHGRVYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQES 237 Query 260 IEETWRMAKMNLAIHGIDNKGLGARWSD--TFARDQHPDVQMDYVMANLPFNIKDWA--R 315 TWR+ KMNLA+ GID RW++ +F +D+ D++ D+++AN PFNI DW R Sbjct 238 NYTTWRLCKMNLAVRGIDAD---IRWNNEGSFHKDELRDLKADFILANPPFNISDWGGER 294 Query 316 NEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVE 375 ED RW FGVPP NANYAW+QHI + LAP G AGVV+ANGSMSSN +GEG+IR +VE Sbjct 295 LREDVRWSFGVPPVGNANYAWLQHIHHHLAPNGTAGVVLANGSMSSNQSGEGEIRKAMVE 354 Query 376 ADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLVDRA 435 AD+V CMVALP QLF ST IP CLWF A++K GK G DR GQVLFIDAR+LG LVDR Sbjct 355 ADVVDCMVALPGQLFYSTQIPACLWFLARNKNPGK-GLRDRRGQVLFIDARKLGVLVDRT 413 Query 436 ERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPGRYV 495 R LT+ EI +I DT+HAWRG A Y+DVPGFCKSATL EI+ + LTPGRYV Sbjct 414 RRELTDAEIQKIADTYHAWRGEPDAG----EYQDVPGFCKSATLEEIRKHGFVLTPGRYV 469 Query 496 GTPAVEDDGEPIDEKMARLS 515 G EDDGEP +EKMARL+ Sbjct 470 GAAQQEDDGEPFEEKMARLA 489 >gi|251772354|gb|EES52922.1| N-6 DNA methylase [Leptospirillum ferrodiazotrophum] Length=522 Score = 539 bits (1389), Expect = 4e-151, Method: Compositional matrix adjust. Identities = 275/525 (53%), Positives = 356/525 (68%), Gaps = 30/525 (5%) Query 18 LKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEESQIE 77 L+ LW+AADKLR ++ A++YK V+LGL+FLKYVSD+++E + E++ E Sbjct 17 LEAKLWQAADKLRNNMDAAEYKHVVLGLLFLKYVSDSFEEHHAKLTNEVSQGANPE---- 72 Query 78 DLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANP 137 DP++Y+ VF VP ARW L N K +P IG++ID+AM A+ + N Sbjct 73 ----DPDEYRADNVFWVPKEARWSVLQANAK-RP--------EIGKVIDDAMVAIERDNK 119 Query 138 TLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEG 197 +L G LP+ Y + +D++RLGELIDL + + EHR+RD++G VYEYFL FA AEG Sbjct 120 SLKGVLPKDYARPGLDKQRLGELIDLVGTIGLGDK-EHRSRDMLGRVYEYFLSQFASAEG 178 Query 198 KRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQ 257 KRGG+F+TP SVV+V+VE+L P GRVYDPCCGSGGMFVQ+EKFI H G D+SIYGQ Sbjct 179 KRGGQFYTPRSVVRVLVEMLAPYKGRVYDPCCGSGGMFVQSEKFIEVHGGRIGDISIYGQ 238 Query 258 ESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDYVMANLPFNIKDWA--R 315 ES TW++A MNLAI GI LG +D+F +D HPD++ DY++AN PFN DW R Sbjct 239 ESNHTTWKLAAMNLAIRGI-AANLGQENADSFHKDLHPDLKADYILANPPFNSSDWGGDR 297 Query 316 NEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVE 375 ED RW +GVPP NAN+AW+QH + LAP G AG V+ANGS+SSN +GEG+IR +VE Sbjct 298 LREDRRWVYGVPPVGNANFAWVQHFISHLAPNGVAGFVLANGSLSSNQSGEGEIRKNMVE 357 Query 376 ADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGK----QGSIDRCGQVLFIDARELGDL 431 AD+V C+VALP QLF ST IPV LWF +++K GK + DR G++LFIDAR+LG + Sbjct 358 ADVVDCIVALPGQLFYSTQIPVSLWFVSRNKKNGKGLEGKPLRDRSGEILFIDARKLGFM 417 Query 432 VDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTP 491 DR R L++E+I +I T+H WRG YEDV GFCKSA L E++ + LTP Sbjct 418 ADRTHRDLSDEDIAKIAGTYHNWRGDGDGT-----YEDVAGFCKSAKLEEVQTHGHVLTP 472 Query 492 GRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 GRYVG EDDGEP +EKM RL+ L E F ESARLE +R+ L Sbjct 473 GRYVGAEEAEDDGEPFEEKMKRLTAQLNEQFAESARLEAEIRKNL 517 >gi|291296826|ref|YP_003508224.1| Site-specific DNA-methyltransferase (adenine-specific) [Meiothermus ruber DSM 1279] gi|290471785|gb|ADD29204.1| Site-specific DNA-methyltransferase (adenine-specific) [Meiothermus ruber DSM 1279] Length=538 Score = 539 bits (1389), Expect = 4e-151, Method: Compositional matrix adjust. Identities = 281/558 (51%), Positives = 373/558 (67%), Gaps = 46/558 (8%) Query 3 PRKKQAPQA-PSTMKEL--KDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERR 59 PR+K PQ+ P+T + + LWK AD LRGS+ A++YK V+LGL+FLKY+SDA++E Sbjct 2 PRRKSNPQSTPTTAATVGYEAELWKMADTLRGSMDAAEYKHVVLGLIFLKYISDAFEELH 61 Query 60 EAIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAK 119 + AE A+G + +DP++Y+ +F VP ARW L + +P Sbjct 62 RKLEAE-RAQGADP-------EDPDEYRAQNIFWVPPEARWAHLKAQAR-------QP-- 104 Query 120 NIGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARD 179 IGQL+D AM + + NP L G LP+ Y + +D+ RLG+LIDL ++ + + E RA+D Sbjct 105 TIGQLVDNAMACIERDNPALKGVLPKEYARPALDKTRLGQLIDLISNIKVGDE-EARAKD 163 Query 180 LMGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTE 239 ++G VYEYFL FA AEGK+GGEF+TP VVK++VE+LEP GRVYDPCCGS GMFVQ+ Sbjct 164 VLGRVYEYFLSQFASAEGKKGGEFYTPRCVVKLLVEMLEPYHGRVYDPCCGSAGMFVQSV 223 Query 240 KFIYEH---DGD----PKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARD 292 +FI H +G+ D+SIYGQES TWR+AKMNLAI GI+ + DTF D Sbjct 224 EFIRAHATGNGNGGRAKADISIYGQESNYTTWRLAKMNLAIRGIEGQ---IAHGDTFHND 280 Query 293 QHPDVQMDYVMANLPFNIKDWA--RNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRA 350 + PD++ D+++AN PFN+ DW R +D RW++GVPP NAN+AW+QHI+Y L+P G A Sbjct 281 KFPDLKADFILANPPFNVSDWGGERLRDDKRWQYGVPPVGNANFAWVQHIVYHLSPTGVA 340 Query 351 GVVMANGSMSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGK 410 G V+ANGSMSSN +GEG+IR ++EA LV CMVALP QLF ST IP CLWF A+D+++ Sbjct 341 GFVLANGSMSSNQSGEGEIRKNLIEAGLVDCMVALPGQLFYSTQIPACLWFLARDRSSRP 400 Query 411 QGSI---------DRCGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAA 461 G+ DR G++LFIDAR++G +VDR R LT+E+I +I T+HAWRG K A Sbjct 401 YGAAGAAPGGKFRDRRGEILFIDARKMGRMVDRTHRELTDEDIAKIASTYHAWRGEKDAG 460 Query 462 VKGIMYEDVPGFCKSATLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEA 521 Y+DVPGFCKSATL E++ Y LTPGRYVG A EDD EP +EKMARL L E Sbjct 461 ----EYQDVPGFCKSATLDEVRKHGYVLTPGRYVGAEAQEDDSEPFEEKMARLVAQLREQ 516 Query 522 FDESARLERVVREQLGRL 539 E+ARL++ + L L Sbjct 517 QAEAARLDKAIAANLKEL 534 >gi|121609950|ref|YP_997757.1| N-6 DNA methylase [Verminephrobacter eiseniae EF01-2] gi|121554590|gb|ABM58739.1| N-6 DNA methylase [Verminephrobacter eiseniae EF01-2] Length=520 Score = 538 bits (1387), Expect = 7e-151, Method: Compositional matrix adjust. Identities = 277/525 (53%), Positives = 357/525 (68%), Gaps = 34/525 (6%) Query 22 LWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEESQIEDLID 81 ++KAADKLRG++ S YK V LGL+FLKY+SD ++ R +++ A+ + ++ Sbjct 19 MFKAADKLRGNMEPSDYKHVALGLIFLKYISDTFEARHKSLLADNPQD----------VE 68 Query 82 DPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANPTLGG 141 D + Y VF VP ARW L + K +P IG LID+AM A+ K N TL Sbjct 69 DRDAYLADNVFWVPKDARWSHLQAHAK-------QP--TIGTLIDDAMRAIEKDNATLQS 119 Query 142 TLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEGKRGG 201 LP+ Y + +++ LGELIDL + +++G H +RD++G VYEYFLG FA AEGKRGG Sbjct 120 VLPKDYARPALNKVMLGELIDLISGITLNQEG-HASRDILGRVYEYFLGQFAGAEGKRGG 178 Query 202 EFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQESIE 261 EF+TP SVV+ +VE+LEP GR+YDPCCGSGGMFVQ+EKF+ EH G D++IYGQES Sbjct 179 EFYTPGSVVRTLVEMLEPYQGRIYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQESNH 238 Query 262 ETWRMAKMNLAIHGIDNKGLGARWSD--TFARDQHPDVQMDYVMANLPFNIKDWA--RNE 317 TWR+AKMNLA+ GID+ RW++ +F +D+ D++ DY++AN PFNI DW R Sbjct 239 VTWRLAKMNLAVRGIDSD---IRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDRLR 295 Query 318 EDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVEAD 377 ED RW+FGVPP NANYAW+QHI++ LAP G AGVV+ANGSMSS+ +GEGDIR ++VE D Sbjct 296 EDVRWKFGVPPVGNANYAWLQHIVHHLAPNGTAGVVLANGSMSSSQSGEGDIRREMVEQD 355 Query 378 LVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSI---DRCGQVLFIDARELGDLVDR 434 +V CMVALP QLF ST IP CLWF A+DK+ G+ G DR +VLFIDAR+LG LVDR Sbjct 356 IVDCMVALPGQLFYSTQIPACLWFLARDKSNGRAGKAYLRDRRKEVLFIDARKLGVLVDR 415 Query 435 AERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPGRY 494 R LT+ ++ RI T+HAWRG Y DVPGFCK+ATL +I+ + LTPGRY Sbjct 416 TRRELTDADVRRIAGTYHAWRGEPGVGA----YADVPGFCKAATLDDIRKHGHVLTPGRY 471 Query 495 VGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 VG V DDG P +EKM L+ L F ESARLE+ +R L L Sbjct 472 VGAEEVADDGTPFEEKMQILTAELNAQFAESARLEQAIRLNLQAL 516 >gi|198284500|ref|YP_002220821.1| N-6 DNA methylase [Acidithiobacillus ferrooxidans ATCC 53993] gi|218667614|ref|YP_002427163.1| type I restriction-modification system, M subunit [Acidithiobacillus ferrooxidans ATCC 23270] gi|198249021|gb|ACH84614.1| N-6 DNA methylase [Acidithiobacillus ferrooxidans ATCC 53993] gi|218519827|gb|ACK80413.1| type I restriction-modification system, M subunit [Acidithiobacillus ferrooxidans ATCC 23270] Length=525 Score = 537 bits (1384), Expect = 2e-150, Method: Compositional matrix adjust. Identities = 271/535 (51%), Positives = 353/535 (66%), Gaps = 30/535 (5%) Query 1 MPPRKKQAPQAPSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERRE 60 MP + +T + L+ LW ADKLRG L A+ YK V+LGL+FLKY+SD + +R E Sbjct 1 MPRGPTKKKTEDTTSQSLESKLWATADKLRGHLDAADYKHVVLGLIFLKYISDRFAQRHE 60 Query 61 AIRAELAAEGMEESQIEDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKN 120 I E A E D ++Y GVF VP S+RW + K +P + Sbjct 61 EIIREEAGTYAAE--------DRDEYTAEGVFWVPASSRWAVVQTAAK-------QP--D 103 Query 121 IGQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDL 180 IG+ ID AM + + NP L LP+ Y + +DQRRLGEL+DL + EH+ARD Sbjct 104 IGKRIDGAMTDIERENPHLKNILPKGYARPTLDQRRLGELVDLIGTIGLG-TAEHQARDT 162 Query 181 MGEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEK 240 +G VYEYFLG FA AEGKRGGEF+TP SVV+ +V +L P GR+YDPCCGSGGMFVQ+EK Sbjct 163 LGRVYEYFLGRFASAEGKRGGEFYTPASVVRTLVTMLAPYKGRIYDPCCGSGGMFVQSEK 222 Query 241 FIYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMD 300 FI H G D+S+YG+ES TW++A MNLAI GI+ LG +DTF +D HPD++ D Sbjct 223 FIEAHGGKVGDISVYGEESNPNTWKLALMNLAIRGIEAD-LGPEAADTFHKDLHPDLRAD 281 Query 301 YVMANLPFNIKDWARN--EEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGS 358 Y++AN PFNI DW + +D RW++G+PP NAN+AW+QH+++ LAP G AG V+ANGS Sbjct 282 YILANPPFNISDWGGDLLRDDKRWQYGIPPTGNANFAWVQHMVHHLAPYGIAGFVLANGS 341 Query 359 MSSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGS----I 414 MSSN++GEG+IR ++EADLV CMVA+P QLF ST IPVCLWF AK++ G+ + Sbjct 342 MSSNTSGEGEIRKNLIEADLVDCMVAMPGQLFYSTQIPVCLWFLAKNRDDGRGMTGKELF 401 Query 415 DRCGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFC 474 +R G+VLFIDAR +G + DR R LT+E+I +I DT+H WRG Y D+PGFC Sbjct 402 ERTGEVLFIDARNMGFMADRTHRELTDEDIQKIADTYHNWRGDGDGE-----YADIPGFC 456 Query 475 KSATLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLE 529 K+A+L +I+ + LTPGRYVG A +DDGEP +EKM RL+K L E RLE Sbjct 457 KAASLDDIRKNGHVLTPGRYVGAAAKDDDGEPFEEKMDRLTKELSAQLAEGRRLE 511 >gi|83720663|ref|YP_443257.1| type I restriction system adenine methylase [Burkholderia thailandensis E264] gi|257139493|ref|ZP_05587755.1| type I restriction system adenine methylase [Burkholderia thailandensis E264] gi|83654488|gb|ABC38551.1| type I restriction system adenine methylase [Burkholderia thailandensis E264] Length=518 Score = 536 bits (1381), Expect = 3e-150, Method: Compositional matrix adjust. Identities = 286/524 (55%), Positives = 356/524 (68%), Gaps = 36/524 (6%) Query 22 LWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAE--LAAEGMEESQIEDL 79 L+KAADKLRG++ S YK V LGL+FLKY+SDA++ R +A+ AE AAE Sbjct 21 LFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHKALLAEDVRAAE---------- 70 Query 80 IDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANPTL 139 D ++Y VF VP ARW L N K PA IG LID+AM A+ K N +L Sbjct 71 --DKDEYLADNVFWVPKEARWSHLQANAK-LPA--------IGTLIDDAMRAIEKDNESL 119 Query 140 GGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEGKR 199 G LP+ Y + +++ LGELIDL + + +G+ R++D++G VYEYFLG FA AEGKR Sbjct 120 KGVLPKDYARPALNKVMLGELIDLISGIALNEEGD-RSKDILGRVYEYFLGQFAGAEGKR 178 Query 200 GGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQES 259 GGEF+TP SVV+V+VE+LEP SGRVYDPCCGSGGMFVQ+EKF++EH G D++IYGQES Sbjct 179 GGEFYTPRSVVRVLVEMLEPYSGRVYDPCCGSGGMFVQSEKFVHEHGGRIGDIAIYGQES 238 Query 260 IEETWRMAKMNLAIHGIDNKGLGARWSD--TFARDQHPDVQMDYVMANLPFNIKDWA--R 315 TWR+AKMNLA+ GID+ RW++ +F +D+ D++ DYV+AN PFNI DW R Sbjct 239 NYTTWRLAKMNLAVRGIDSD---IRWNNEGSFHKDELRDLKADYVLANPPFNISDWGGDR 295 Query 316 NEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVE 375 ED RW+FG PP NANYAW+QHI + LAP G AGVV+ANGSMSSN +GEG+IR ++E Sbjct 296 LREDVRWKFGAPPVGNANYAWLQHIFHHLAPNGTAGVVLANGSMSSNQSGEGEIRRAMIE 355 Query 376 ADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLVDRA 435 AD V CMVALP QLF ST IP CLWF A++K G G DR GQVLFIDAR+LG L+DR Sbjct 356 ADAVDCMVALPGQLFYSTQIPACLWFLARNKNPGG-GLRDRRGQVLFIDARKLGVLIDRT 414 Query 436 ERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPGRYV 495 R L +++I RI D++HAWRG K A Y DV GFCKSA+L EI+ + LTPGRYV Sbjct 415 RRELNDDDIKRIADSYHAWRGEKEAG----EYADVLGFCKSASLDEIRKHGHVLTPGRYV 470 Query 496 GTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQLGRL 539 G A DDGEP DE M RLS E R++ + L L Sbjct 471 GAEAQADDGEPFDEVMRRLSAQWRAQQLEGQRVDDAIERNLREL 514 >gi|114330559|ref|YP_746781.1| N-6 DNA methylase [Nitrosomonas eutropha C91] gi|114307573|gb|ABI58816.1| N-6 DNA methylase [Nitrosomonas eutropha C91] Length=542 Score = 535 bits (1377), Expect = 1e-149, Method: Compositional matrix adjust. Identities = 286/543 (53%), Positives = 363/543 (67%), Gaps = 48/543 (8%) Query 22 LWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAEGMEESQIEDLID 81 L+KAADKLRG++ S YK V LGL+FLKY+SDA++ R + AE AA Sbjct 19 LFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHAELAAESAAAAE---------- 68 Query 82 DPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANPTLGG 141 D ++Y +F VP RW L N K +P IG LID+AM A+ K N +L G Sbjct 69 DKDEYLADNIFWVPKEGRWSHLKANAK-RP--------EIGTLIDDAMRAIEKDNESLKG 119 Query 142 TLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEGKRGG 201 LP+ Y + +++ LGELIDL + + G+ +++D++G VYEYFL FA AEGKRGG Sbjct 120 VLPKDYARPALNKVMLGELIDLISGIAMNEGGD-KSKDVLGRVYEYFLSQFAGAEGKRGG 178 Query 202 EFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQESIE 261 EF+TP SVV+V+V++LEP +GRVYDPCCGSGGMFVQ+EKF+ EH G D++IYGQES Sbjct 179 EFYTPRSVVQVLVQMLEPYAGRVYDPCCGSGGMFVQSEKFVLEHGGRIGDIAIYGQESNY 238 Query 262 ETWRMAKMNLAIHGIDNKGLGARWSD--TFARDQHPDVQMDYVMANLPFNIKDWA--RNE 317 TWR+AKMNLA+ GID+ RW++ +F +D+ D++ D+++AN PFNI DW R Sbjct 239 TTWRLAKMNLAVRGIDSD---IRWNNEGSFHKDELRDLRFDHILANPPFNISDWGGDRLR 295 Query 318 EDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVEAD 377 EDPRW+FGVPP NANYAW+QHI + LAP G AGVV+ANGSMSSN +GEG+IR +VEAD Sbjct 296 EDPRWQFGVPPVGNANYAWLQHIHWHLAPFGTAGVVLANGSMSSNQSGEGEIRKAMVEAD 355 Query 378 LVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSI--------DRCGQVLFIDARELG 429 V CMV LP QLF ST IP CLWF A+DK+ GK+GS+ DR G+VLFIDAR +G Sbjct 356 AVDCMVTLPGQLFYSTQIPACLWFLARDKSNGKRGSLSKGGETLRDRRGEVLFIDARNMG 415 Query 430 DLVDRAERALTNEEIVRIGDTFHAWRGSK-------SAAVKG------IMYEDVPGFCKS 476 LVDR R LT+E+I +I DT+HAWRG K SA+V G Y D+PGFCK+ Sbjct 416 TLVDRTRRELTDEDIQKIADTYHAWRGEKVAGDAQGSASVAGGRMPGATQYADIPGFCKA 475 Query 477 ATLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 ATL EI+ + LTPGRYVG A EDDGE +KM RLS E E+ARL+ + L Sbjct 476 ATLEEIRKHGHVLTPGRYVGAEAAEDDGEAFADKMQRLSAQWREQQQEAARLDVEIEANL 535 Query 537 GRL 539 L Sbjct 536 REL 538 >gi|167847545|ref|ZP_02473053.1| N-6 DNA methylase [Burkholderia pseudomallei B7210] gi|226198245|ref|ZP_03793816.1| type I restriction-modification system, M subunit [Burkholderia pseudomallei Pakistan 9] gi|225929765|gb|EEH25781.1| type I restriction-modification system, M subunit [Burkholderia pseudomallei Pakistan 9] Length=548 Score = 534 bits (1376), Expect = 1e-149, Method: Compositional matrix adjust. Identities = 283/544 (53%), Positives = 361/544 (67%), Gaps = 32/544 (5%) Query 11 APSTMKELKDTLWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAELAAE- 69 A S ++LK TLW AADKLR S+ A++YK ++LGL+FLKY+SDA+DERR A+LAA Sbjct 18 ALSVNQDLKKTLWAAADKLRSSMDAAEYKHIVLGLIFLKYISDAFDERR----AQLAAAF 73 Query 70 GMEESQI--------EDLIDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNI 121 G +E + + +++ + Y VF VP SARW+ + K +P +I Sbjct 74 GNQEDDLYLPDAADHAEALEERDYYTMANVFWVPASARWESIRAQAK-------QP--DI 124 Query 122 GQLIDEAMDAVMKANPTLGGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLM 181 G ID A++A+ N +L G L + + + ++ RLGEL+DL ++ F H A+DL+ Sbjct 125 GVRIDSALEAIEADNKSLKGILDKRFGRTQLEPGRLGELVDLISTVGFGEG--HHAKDLL 182 Query 182 GEVYEYFLGNFARAEGKRGGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKF 241 GEVYEYFLG FA AEGK+GG+F+TP SVV+V+VEVL P GRVYDPCCGSGGMFVQ+EKF Sbjct 183 GEVYEYFLGQFATAEGKKGGQFYTPASVVRVLVEVLAPHEGRVYDPCCGSGGMFVQSEKF 242 Query 242 IYEHDGDPKDVSIYGQESIEETWRMAKMNLAIHGIDNKGLGARWSDTFARDQHPDVQMDY 301 I H G D+SIYGQE+ TWR+ MNLAI G+ LG +DTF RDQHPD++ DY Sbjct 243 IESHGGKADDISIYGQEANPTTWRLVAMNLAIRGL-AADLGKEPADTFHRDQHPDLRADY 301 Query 302 VMANLPFNIKDWA--RNEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSM 359 V+AN PFNI DW R +D RW +GVPPA NANYAW+QHIL+ L+P G+AGVV+ANGSM Sbjct 302 VLANPPFNISDWGGERLADDRRWAYGVPPAGNANYAWLQHILHHLSPRGQAGVVLANGSM 361 Query 360 SSNSNGEGDIRAQIVEADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAA----GKQGSID 415 SS+ +GEG+IR +VEAD+V MVALP QLF +T IP CLWF AKDK+ G + S D Sbjct 362 SSSQSGEGEIRRAMVEADVVDVMVALPPQLFFNTQIPACLWFLAKDKSGTPVPGGKPSRD 421 Query 416 RCGQVLFIDARELGDLVDRAERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCK 475 R G+VLFIDAR+LG + R R +E+I RI T H WR Y DVPGFC+ Sbjct 422 RRGEVLFIDARKLGRMASRVVRVFDDEDIARIASTVHRWRADGEDGADE-PYADVPGFCR 480 Query 476 SATLAEIKATDYALTPGRYVGTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQ 535 S +AEI Y LTPGRYVG EDD E EKM RL+ L E + + L+ V+RE+ Sbjct 481 SVQVAEIAEHGYVLTPGRYVGAEETEDDDEAFGEKMERLTAQLAEQMAKGSELDAVIREK 540 Query 536 LGRL 539 LG L Sbjct 541 LGGL 544 >gi|302878446|ref|YP_003847010.1| Site-specific DNA-methyltransferase (adenine-specific) [Gallionella capsiferriformans ES-2] gi|302581235|gb|ADL55246.1| Site-specific DNA-methyltransferase (adenine-specific) [Gallionella capsiferriformans ES-2] Length=516 Score = 534 bits (1375), Expect = 2e-149, Method: Compositional matrix adjust. Identities = 274/521 (53%), Positives = 356/521 (69%), Gaps = 36/521 (6%) Query 22 LWKAADKLRGSLSASQYKDVILGLVFLKYVSDAYDERREAIRAE--LAAEGMEESQIEDL 79 ++KAADKLRG++ S YK V LGL+FLKY+SDA++ R +A+ E AAE Sbjct 19 MFKAADKLRGNMEPSDYKHVALGLIFLKYISDAFEARHKALLEEDPQAAE---------- 68 Query 80 IDDPEQYQGYGVFVVPVSARWKFLAENTKGKPAVGGEPAKNIGQLIDEAMDAVMKANPTL 139 D ++Y VF VP ARW L N K IG LID+AM A+ K N +L Sbjct 69 --DKDEYLADNVFWVPKDARWSHLQANAK---------LPTIGTLIDDAMRAIEKDNESL 117 Query 140 GGTLPRLYNKDNIDQRRLGELIDLFNSARFSRQGEHRARDLMGEVYEYFLGNFARAEGKR 199 G LP+ Y + +++ LGELIDL + + +G H +RD++G VYEYFLG FA AEGKR Sbjct 118 KGVLPKDYARPALNKVMLGELIDLISGIALNEEG-HASRDILGRVYEYFLGQFAGAEGKR 176 Query 200 GGEFFTPPSVVKVIVEVLEPSSGRVYDPCCGSGGMFVQTEKFIYEHDGDPKDVSIYGQES 259 GGEF+TP SVV+V+VE+LEP GR+YDPCCGSGGMFVQ+EKF+ EH G D++IYGQES Sbjct 177 GGEFYTPRSVVRVLVEMLEPYQGRIYDPCCGSGGMFVQSEKFVQEHGGRIGDIAIYGQES 236 Query 260 IEETWRMAKMNLAIHGIDNKGLGARWSD--TFARDQHPDVQMDYVMANLPFNIKDWA--R 315 TWR+AKMNLA+ GID+ RW++ +F +D+ D++ DY++AN PFNI DW R Sbjct 237 NYVTWRLAKMNLAVRGIDSD---IRWNNEGSFHKDELRDLKADYILANPPFNISDWGGDR 293 Query 316 NEEDPRWRFGVPPANNANYAWIQHILYKLAPGGRAGVVMANGSMSSNSNGEGDIRAQIVE 375 ED RW+FG PP NANYAW+QHI++ LAP G AGVV+ANGSMSS +GEGDIR ++VE Sbjct 294 LREDVRWKFGAPPVGNANYAWLQHIVHHLAPNGTAGVVLANGSMSSTQSGEGDIRREMVE 353 Query 376 ADLVSCMVALPTQLFRSTGIPVCLWFFAKDKAAGKQGSIDRCGQVLFIDARELGDLVDRA 435 D++ CMVALP QLF ST IP CLWF A++K G G DR G+VLFIDAR+LG LVDR Sbjct 354 KDILDCMVALPGQLFYSTQIPACLWFLARNKNPG-NGWRDRRGEVLFIDARKLGVLVDRT 412 Query 436 ERALTNEEIVRIGDTFHAWRGSKSAAVKGIMYEDVPGFCKSATLAEIKATDYALTPGRYV 495 R L++ ++ +I DT+HAWRG +A YED+ GFCKSA+L +I+ + + PGRYV Sbjct 413 RRELSDADVQKIADTYHAWRGEPNAGA----YEDISGFCKSASLDDIRKQGHVVAPGRYV 468 Query 496 GTPAVEDDGEPIDEKMARLSKALLEAFDESARLERVVREQL 536 G +DD EP EK++RLS L F E+A+LE+ ++ L Sbjct 469 GAAETDDDEEPTSEKLSRLSSQLRTHFSENAQLEQAIKNAL 509 Lambda K H 0.318 0.136 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 1189573419810 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40