BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv2760c
Length=89
Score E
Sequences producing significant alignments: (Bits) Value
gi|15609897|ref|NP_217276.1| hypothetical protein Rv2760c [Mycob... 169 2e-40
gi|84497914|ref|ZP_00996711.1| hypothetical protein JNB_17543 [J... 57.8 5e-07
gi|270208573|ref|YP_003329344.1| hypothetical protein pSmeSM11ap... 48.5 4e-04
gi|154243677|ref|YP_001409250.1| transcription factor [Xanthobac... 45.4 0.003
gi|256826048|ref|YP_003150008.1| Rv0623-like transcription facto... 43.5 0.011
gi|256824142|ref|YP_003148102.1| Rv0623-like transcription facto... 42.7 0.019
gi|120402182|ref|YP_952011.1| transcription factor [Mycobacteriu... 42.0 0.030
gi|336116292|ref|YP_004571058.1| hypothetical protein MLP_06410 ... 39.7 0.16
gi|254419903|ref|ZP_05033627.1| probable ribbon-helix-helix tran... 38.9 0.27
gi|90422854|ref|YP_531224.1| transcription factor [Rhodopseudomo... 37.4 0.66
gi|87123253|ref|ZP_01079104.1| hypothetical protein RS9917_05320... 36.6 1.3
gi|15607748|ref|NP_215122.1| hypothetical protein Rv0608 [Mycoba... 36.2 1.6
gi|258650322|ref|YP_003199478.1| Rv0623 family protein transcrip... 35.8 2.3
gi|84495503|ref|ZP_00994622.1| hypothetical protein JNB_11894 [J... 35.0 3.9
gi|47230319|emb|CAG10733.1| unnamed protein product [Tetraodon n... 34.3 5.8
gi|298529280|ref|ZP_07016683.1| Rv0623 family protein transcript... 34.3 7.0
gi|293980660|ref|YP_003543418.1| hypothetical protein SJA_P2-001... 33.9 7.5
gi|327261413|ref|XP_003215525.1| PREDICTED: LOW QUALITY PROTEIN:... 33.9 7.6
gi|192292980|ref|YP_001993585.1| Rv0623 family protein transcrip... 33.9 9.2
gi|167644912|ref|YP_001682575.1| hypothetical protein Caul_0946 ... 33.5 10.0
>gi|15609897|ref|NP_217276.1| hypothetical protein Rv2760c [Mycobacterium tuberculosis H37Rv]
gi|15842298|ref|NP_337335.1| hypothetical protein MT2830 [Mycobacterium tuberculosis CDC1551]
gi|31793934|ref|NP_856427.1| hypothetical protein Mb2781c [Mycobacterium bovis AF2122/97]
79 more sequence titles
Length=89
Score = 169 bits (427), Expect = 2e-40, Method: Compositional matrix adjust.
Identities = 89/89 (100%), Positives = 89/89 (100%), Gaps = 0/89 (0%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR
Sbjct 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
Query 61 DLDKLLSDDDKRLIRRHEVDLYDDSGLPR 89
DLDKLLSDDDKRLIRRHEVDLYDDSGLPR
Sbjct 61 DLDKLLSDDDKRLIRRHEVDLYDDSGLPR 89
>gi|84497914|ref|ZP_00996711.1| hypothetical protein JNB_17543 [Janibacter sp. HTCC2649]
gi|84381414|gb|EAP97297.1| hypothetical protein JNB_17543 [Janibacter sp. HTCC2649]
Length=87
Score = 57.8 bits (138), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 38/92 (42%), Positives = 60/92 (66%), Gaps = 8/92 (8%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
M+LNIK++R V L R++AARTGT QT A+E A+ R L++L RE A ++++R +Q L
Sbjct 1 MALNIKNERVVTLARDVAARTGTTQTGAIESALERYLADLVRE--AESDSKRRRIDQLLA 58
Query 61 DLDKLLSDDDKRLIRRHEV--DLYD-DSGLPR 89
++D +D + E+ ++YD +GLPR
Sbjct 59 EIDAERTDGGPTV---EEIMDEMYDPQTGLPR 87
>gi|270208573|ref|YP_003329344.1| hypothetical protein pSmeSM11ap046 [Sinorhizobium meliloti]
gi|76880847|gb|ABA56017.1| conserved hypothetical protein [Sinorhizobium meliloti]
Length=85
Score = 48.5 bits (114), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 36/92 (40%), Positives = 50/92 (55%), Gaps = 12/92 (13%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDR----EDRARAEARRAAAE 56
MSLNIK+ TVAL ELA R G ++TAA+ A++ RL + +DR E R A
Sbjct 1 MSLNIKNPATVALADELARRQGISKTAAIHQALSERLHRMGHGEVSQDRLLGELR--AIR 58
Query 57 QTLRDLDKLLSDDDKRLIRRHEVDLYDDSGLP 88
Q + L +L S D+ +I YD+ G+P
Sbjct 59 QRIARLPELDSRSDEEIIG------YDEHGIP 84
>gi|154243677|ref|YP_001409250.1| transcription factor [Xanthobacter autotrophicus Py2]
gi|154162799|gb|ABS70014.1| Rv0623 family protein transcription factor [Xanthobacter autotrophicus
Py2]
Length=85
Score = 45.4 bits (106), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 33/88 (38%), Positives = 48/88 (55%), Gaps = 4/88 (4%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
MSLNIK+ TVAL ELA R G +TAA+ A++ RL + D A+AR + +R
Sbjct 1 MSLNIKNPATVALADELARRQGVTKTAAIHQALSERLHRMGYGD--TAQARLLGELRAIR 58
Query 61 DLDKLLSDDDKRLIRRHEVDLYDDSGLP 88
+ L + D R E+ +D+ G+P
Sbjct 59 ERVARLPELDTR--SDEEIVGFDEHGIP 84
>gi|256826048|ref|YP_003150008.1| Rv0623-like transcription factor [Kytococcus sedentarius DSM
20547]
gi|256689441|gb|ACV07243.1| Rv0623-like transcription factor [Kytococcus sedentarius DSM
20547]
Length=88
Score = 43.5 bits (101), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 36/95 (38%), Positives = 49/95 (52%), Gaps = 13/95 (13%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
M+LNIK++R L RE AA GT+QT+A+E A+ L A RR+ E+ R
Sbjct 1 MALNIKNERVHQLAREAAALRGTSQTSALEAALEEYLER-------HAAGRRSEDERWER 53
Query 61 D---LDKL---LSDDDKRLIRRHEVDLYDDSGLPR 89
+D++ L D + DLYDD GLPR
Sbjct 54 VTALVDQIRIDLQDAGSGSLSEELTDLYDDDGLPR 88
>gi|256824142|ref|YP_003148102.1| Rv0623-like transcription factor [Kytococcus sedentarius DSM
20547]
gi|256687535|gb|ACV05337.1| Rv0623-like transcription factor [Kytococcus sedentarius DSM
20547]
Length=103
Score = 42.7 bits (99), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 31/88 (36%), Positives = 45/88 (52%), Gaps = 7/88 (7%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
M+L IK+ R L RE A R+G +Q + +E A+ R L+ D A RR ++ L
Sbjct 22 MALTIKNDRVCDLAREAAQRSGQSQVSVIEQALERYLA-----DHAEPVGRRV--DEVLA 74
Query 61 DLDKLLSDDDKRLIRRHEVDLYDDSGLP 88
+D L+ D +R LYD+ GLP
Sbjct 75 RIDASLAPGDAAAMRVELDRLYDERGLP 102
>gi|120402182|ref|YP_952011.1| transcription factor [Mycobacterium vanbaalenii PYR-1]
gi|119955000|gb|ABM12005.1| Rv0623 family protein transcription factor [Mycobacterium vanbaalenii
PYR-1]
Length=81
Score = 42.0 bits (97), Expect = 0.030, Method: Compositional matrix adjust.
Identities = 35/93 (38%), Positives = 47/93 (51%), Gaps = 18/93 (19%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRAR---AEARRAAAEQ 57
M+LNIK ++ V++LA TG +Q AV AV RLS + ++D A A RR A
Sbjct 1 MALNIKDEKVHDAVKQLARLTGESQAQAVATAVQERLSRVQQDDLAERLLALGRRTAQRM 60
Query 58 T--LRDLDKLLSDDDKRLIRRHEVDLYDDSGLP 88
T ++LD H LYDD+GLP
Sbjct 61 TSATKNLD-------------HGELLYDDAGLP 80
>gi|336116292|ref|YP_004571058.1| hypothetical protein MLP_06410 [Microlunatus phosphovorus NM-1]
gi|334684070|dbj|BAK33655.1| hypothetical protein MLP_06410 [Microlunatus phosphovorus NM-1]
Length=84
Score = 39.7 bits (91), Expect = 0.16, Method: Compositional matrix adjust.
Identities = 36/90 (40%), Positives = 45/90 (50%), Gaps = 7/90 (7%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
M+LNIK T L RELAA TG + T A A+ RL +R RA A +A L
Sbjct 1 MALNIKDPETDRLARELAAATGESITVAARRAIEERL------ERVRARADAGSASVDLG 54
Query 61 DL-DKLLSDDDKRLIRRHEVDLYDDSGLPR 89
DL ++ S D + E+ Y D GLPR
Sbjct 55 DLIERARSRPDLDVRSAEEILGYGDDGLPR 84
>gi|254419903|ref|ZP_05033627.1| probable ribbon-helix-helix transcription factor, Rv0623 family
[Brevundimonas sp. BAL3]
gi|196186080|gb|EDX81056.1| probable ribbon-helix-helix transcription factor, Rv0623 family
[Brevundimonas sp. BAL3]
Length=86
Score = 38.9 bits (89), Expect = 0.27, Method: Compositional matrix adjust.
Identities = 29/89 (33%), Positives = 46/89 (52%), Gaps = 3/89 (3%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
M L+IK T R +A R G + T A++ A+ + EL E+ A A RA+ + L
Sbjct 1 MGLSIKRAETERKARAVAERLGVSLTEAIDIALDKTWKELTAEEGA---AERASKREALF 57
Query 61 DLDKLLSDDDKRLIRRHEVDLYDDSGLPR 89
+ L D R ++ + ++YD+ GLPR
Sbjct 58 AYLRTLPPGDGRSLQEVDDEMYDEHGLPR 86
>gi|90422854|ref|YP_531224.1| transcription factor [Rhodopseudomonas palustris BisB18]
gi|90104868|gb|ABD86905.1| Rv0623-like transcription factor [Rhodopseudomonas palustris
BisB18]
Length=84
Score = 37.4 bits (85), Expect = 0.66, Method: Compositional matrix adjust.
Identities = 33/93 (36%), Positives = 47/93 (51%), Gaps = 13/93 (13%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
M+L+IK T L R LA TG N T A + A+ +RLS L +R++A Q +
Sbjct 1 MALSIKDPETERLARTLARLTGENITTATKRAIEQRLSRLA------GPSRKSALLQEMA 54
Query 61 DLDKLLSD----DDKRLIRRHEVDLYDDSGLPR 89
D+ + S+ DD+ E+ YD GLPR
Sbjct 55 DIRRRWSELPVVDDR---TPEEILGYDAHGLPR 84
>gi|87123253|ref|ZP_01079104.1| hypothetical protein RS9917_05320 [Synechococcus sp. RS9917]
gi|86168973|gb|EAQ70229.1| hypothetical protein RS9917_05320 [Synechococcus sp. RS9917]
Length=87
Score = 36.6 bits (83), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 31/89 (35%), Positives = 44/89 (50%), Gaps = 6/89 (6%)
Query 3 LNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLRDL 62
+NIK A+ RELAA GT T AV A+ L+ + ++A +R EQ L +L
Sbjct 1 MNIKDPAVHAMARELAAHKGTTVTDAVRQALKAELARVGSASTSQAAEQR---EQQLMEL 57
Query 63 ---DKLLSDDDKRLIRRHEVDLYDDSGLP 88
+ L + R + LYDD+GLP
Sbjct 58 LPRFRHLPWPEGVSSRELQDALYDDNGLP 86
>gi|15607748|ref|NP_215122.1| hypothetical protein Rv0608 [Mycobacterium tuberculosis H37Rv]
gi|15840008|ref|NP_335045.1| hypothetical protein MT0637 [Mycobacterium tuberculosis CDC1551]
gi|31791790|ref|NP_854283.1| hypothetical protein Mb0624 [Mycobacterium bovis AF2122/97]
77 more sequence titles
Length=81
Score = 36.2 bits (82), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 32/91 (36%), Positives = 45/91 (50%), Gaps = 14/91 (15%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDRED---RARAEARRAAAEQ 57
M+LNIK V+++A TG +Q AV AV RL+ L +D R A + A+
Sbjct 1 MALNIKDPSVHQAVKQIAKITGESQARAVATAVNERLARLRSDDLAARLLAIGHKTASR- 59
Query 58 TLRDLDKLLSDDDKRLIRRHEVDLYDDSGLP 88
+S + KRL H+ LYD+ GLP
Sbjct 60 --------MSPEAKRL--DHDALLYDERGLP 80
>gi|258650322|ref|YP_003199478.1| Rv0623 family protein transcription factor [Nakamurella multipartita
DSM 44233]
gi|258553547|gb|ACV76489.1| Rv0623 family protein transcription factor [Nakamurella multipartita
DSM 44233]
Length=84
Score = 35.8 bits (81), Expect = 2.3, Method: Compositional matrix adjust.
Identities = 35/93 (38%), Positives = 45/93 (49%), Gaps = 13/93 (13%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
M LNIK T L RELAA G + T A A+ RLS L AR+ A + L
Sbjct 1 MVLNIKDPETDRLARELAAEAGESLTVATRRAIEERLSRL--------RARKRANDPDL- 51
Query 61 DLDKLLSDDDKRLI--RRHEVDL--YDDSGLPR 89
LD+ + +R + R D+ YD+ GLPR
Sbjct 52 GLDEFIRRGRERAVLDERSPDDIIGYDEHGLPR 84
>gi|84495503|ref|ZP_00994622.1| hypothetical protein JNB_11894 [Janibacter sp. HTCC2649]
gi|84384996|gb|EAQ00876.1| hypothetical protein JNB_11894 [Janibacter sp. HTCC2649]
Length=86
Score = 35.0 bits (79), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 21/46 (46%), Positives = 26/46 (57%), Gaps = 0/46 (0%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRA 46
M+LNIK T L RELAA TG + T A A+ RL + + RA
Sbjct 1 MALNIKDPETDRLARELAAATGESITVAARRAIEERLERIHHQQRA 46
>gi|47230319|emb|CAG10733.1| unnamed protein product [Tetraodon nigroviridis]
Length=1411
Score = 34.3 bits (77), Expect = 5.8, Method: Composition-based stats.
Identities = 24/65 (37%), Positives = 34/65 (53%), Gaps = 3/65 (4%)
Query 25 QTAAVE-DAVARRLSELDREDRARAEARRAAAEQTLRDLDKLLSDDDKRLIRRHEV--DL 81
Q A E + +A +L+E RE R E R A R L+KLLS+ + LIR ++ +
Sbjct 611 QMALTELETLAEKLNEKKREADQRCEIRHIAKAMNERYLNKLLSNGSRYLIRSDDMIETV 670
Query 82 YDDSG 86
Y D G
Sbjct 671 YSDRG 675
>gi|298529280|ref|ZP_07016683.1| Rv0623 family protein transcription factor [Desulfonatronospira
thiodismutans ASO3-1]
gi|298510716|gb|EFI34619.1| Rv0623 family protein transcription factor [Desulfonatronospira
thiodismutans ASO3-1]
Length=83
Score = 34.3 bits (77), Expect = 7.0, Method: Compositional matrix adjust.
Identities = 28/86 (33%), Positives = 44/86 (52%), Gaps = 5/86 (5%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
M+L+I++ L RE+AAR+G N T A+ ++ RL L + +A A R Q +
Sbjct 1 MALSIRNPEAERLAREVAARSGENITQAIIHSLEERLQRLGHQQQA---AARLEELQAIA 57
Query 61 DLDKLLSDDDKRLIRRHEVDLYDDSG 86
+ L D D+R E+ YD+ G
Sbjct 58 GRCQALPDLDQR--SEEEILGYDEHG 81
>gi|293980660|ref|YP_003543418.1| hypothetical protein SJA_P2-00160 [Sphingobium japonicum UT26S]
gi|292677677|dbj|BAI99192.1| conserved hypothetical protein [Sphingobium japonicum UT26S]
Length=82
Score = 33.9 bits (76), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 24/89 (27%), Positives = 44/89 (50%), Gaps = 7/89 (7%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLR 60
MSLN+K L + +A TG + T V +A+ R + ++R+ +A+ + L
Sbjct 1 MSLNVKDPEAHRLAQAIAQATGQSMTRVVTEALRERFARIERQK------SKASVAELLT 54
Query 61 DLDKLLSDDDKRLIRRHEVDLYDDSGLPR 89
D+ + + + E+ YDD+GLP+
Sbjct 55 IADRAATHVKRPYVDHAEL-FYDDNGLPK 82
>gi|327261413|ref|XP_003215525.1| PREDICTED: LOW QUALITY PROTEIN: rho guanine nucleotide exchange
factor 10-like [Anolis carolinensis]
Length=1405
Score = 33.9 bits (76), Expect = 7.6, Method: Composition-based stats.
Identities = 22/65 (34%), Positives = 36/65 (56%), Gaps = 3/65 (4%)
Query 25 QTAAVE-DAVARRLSELDREDRARAEARRAAAEQTLRDLDKLLSDDDKRLIRRHEV--DL 81
Q A E + +A +L+E R+ R E ++ A R L+KLLS ++ LIR ++ +
Sbjct 654 QMALTELETLAEKLNERKRDADQRCEVKQIAKAMNERYLNKLLSSGNRHLIRSDDMLETV 713
Query 82 YDDSG 86
Y+D G
Sbjct 714 YNDKG 718
>gi|192292980|ref|YP_001993585.1| Rv0623 family protein transcription factor [Rhodopseudomonas
palustris TIE-1]
gi|192286729|gb|ACF03110.1| Rv0623 family protein transcription factor [Rhodopseudomonas
palustris TIE-1]
Length=83
Score = 33.9 bits (76), Expect = 9.2, Method: Compositional matrix adjust.
Identities = 33/99 (34%), Positives = 43/99 (44%), Gaps = 28/99 (28%)
Query 1 MSLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAE----------- 49
M LNIK+ L ELA TG + TAAV +A+ +L+ RE R R
Sbjct 1 MHLNIKNDEAHQLATELARMTGESLTAAVTNALREQLA---REHRRRQTDQIAQRLLKIG 57
Query 50 ARRAAAEQTLRDLDKLLSDDDKRLIRRHEVDLYDDSGLP 88
R AA T R D++L YD++GLP
Sbjct 58 GRYAAVPDTGRTPDEILG--------------YDENGLP 82
>gi|167644912|ref|YP_001682575.1| hypothetical protein Caul_0946 [Caulobacter sp. K31]
gi|167347342|gb|ABZ70077.1| hypothetical protein Caul_0946 [Caulobacter sp. K31]
Length=124
Score = 33.5 bits (75), Expect = 10.0, Method: Compositional matrix adjust.
Identities = 29/94 (31%), Positives = 39/94 (42%), Gaps = 16/94 (17%)
Query 2 SLNIKSQRTVALVRELAARTGTNQTAAVEDAVARRLSELDREDRARAEARRAAAEQTLRD 61
+ I++ V +RELA G T VE AV L R A E RRA +TL
Sbjct 41 PIQIRNAEVVENIRELARLRGAGLTETVEAAVRETLERERRHQTASLEGRRAKVMETLER 100
Query 62 L------DKLLSDDDKRLIRRHEVDLYDDSGLPR 89
++L+D DLYD+ G P+
Sbjct 101 FWALPRTGEILTD----------ADLYDEDGFPK 124
Lambda K H
0.316 0.129 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 129638988780
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40