BLASTP 2.2.25+
Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
15,229,318 sequences; 5,219,829,388 total letters
Query= Rv2764c
Length=263
Score E
Sequences producing significant alignments: (Bits) Value
gi|15842302|ref|NP_337339.1| thymidylate synthase [Mycobacterium... 546 8e-154
gi|340707881|pdb|3QJ7|A Chain A, Crystal Structure Of The Mycoba... 545 2e-153
gi|15609901|ref|NP_217280.1| thymidylate synthase [Mycobacterium... 545 3e-153
gi|253798154|ref|YP_003031155.1| thymidylate synthase thyA [Myco... 545 3e-153
gi|148823952|ref|YP_001288706.1| thymidylate synthase [Mycobacte... 543 9e-153
gi|41408967|ref|NP_961803.1| thymidylate synthase [Mycobacterium... 506 1e-141
gi|118465321|ref|YP_882829.1| thymidylate synthase [Mycobacteriu... 506 1e-141
gi|342858374|ref|ZP_08715029.1| thymidylate synthase [Mycobacter... 504 4e-141
gi|254821236|ref|ZP_05226237.1| thymidylate synthase [Mycobacter... 500 8e-140
gi|240171163|ref|ZP_04749822.1| thymidylate synthase [Mycobacter... 500 9e-140
gi|296171672|ref|ZP_06852886.1| thymidylate synthase [Mycobacter... 499 2e-139
gi|118617725|ref|YP_906057.1| thymidylate synthase [Mycobacteriu... 498 3e-139
gi|183981970|ref|YP_001850261.1| thymidylate synthase ThyA [Myco... 495 2e-138
gi|108799079|ref|YP_639276.1| thymidylate synthase [Mycobacteriu... 493 2e-137
gi|118467946|ref|YP_887007.1| thymidylate synthase [Mycobacteriu... 489 2e-136
gi|145224587|ref|YP_001135265.1| thymidylate synthase [Mycobacte... 488 4e-136
gi|315444918|ref|YP_004077797.1| thymidylate synthase [Mycobacte... 487 6e-136
gi|120403371|ref|YP_953200.1| thymidylate synthase [Mycobacteriu... 484 6e-135
gi|15827801|ref|NP_302064.1| thymidylate synthase [Mycobacterium... 482 2e-134
gi|333991150|ref|YP_004523764.1| thymidylate synthase ThyA [Myco... 470 8e-131
gi|169630173|ref|YP_001703822.1| thymidylate synthase ThyA [Myco... 463 1e-128
gi|262202109|ref|YP_003273317.1| thymidylate synthase [Gordonia ... 460 7e-128
gi|343927028|ref|ZP_08766516.1| thymidylate synthase [Gordonia a... 460 9e-128
gi|326384524|ref|ZP_08206204.1| thymidylate synthase [Gordonia n... 445 4e-123
gi|226307948|ref|YP_002767908.1| thymidylate synthase [Rhodococc... 445 4e-123
gi|296139474|ref|YP_003646717.1| thymidylate synthase [Tsukamure... 442 2e-122
gi|319950119|ref|ZP_08024059.1| thymidylate synthase [Dietzia ci... 442 3e-122
gi|334338011|ref|YP_004543163.1| Thymidylate synthase [Isopteric... 441 6e-122
gi|325676379|ref|ZP_08156058.1| thymidylate synthase [Rhodococcu... 439 2e-121
gi|226361376|ref|YP_002779154.1| thymidylate synthase [Rhodococc... 439 2e-121
gi|312138557|ref|YP_004005893.1| thymidylate synthase [Rhodococc... 439 3e-121
gi|111019241|ref|YP_702213.1| thymidylate synthase [Rhodococcus ... 437 8e-121
gi|213964887|ref|ZP_03393086.1| thymidylate synthase [Corynebact... 434 5e-120
gi|300785995|ref|YP_003766286.1| thymidylate synthase [Amycolato... 434 7e-120
gi|54026996|ref|YP_121238.1| thymidylate synthase [Nocardia farc... 432 2e-119
gi|271966278|ref|YP_003340474.1| Thymidylate synthase [Streptosp... 432 4e-119
gi|302532527|ref|ZP_07284869.1| thymidylate synthase [Streptomyc... 429 1e-118
gi|269957617|ref|YP_003327406.1| thymidylate synthase [Xylanimon... 428 3e-118
gi|256394947|ref|YP_003116511.1| thymidylate synthase [Catenulis... 426 1e-117
gi|302529833|ref|ZP_07282175.1| thymidylate synthase [Streptomyc... 425 3e-117
gi|260579743|ref|ZP_05847601.1| thymidylate synthase [Corynebact... 425 4e-117
gi|227487755|ref|ZP_03918071.1| thymidylate synthase [Corynebact... 424 7e-117
gi|68535511|ref|YP_250216.1| thymidylate synthase [Corynebacteri... 423 1e-116
gi|297153967|gb|ADI03679.1| thymidylate synthase [Streptomyces b... 422 2e-116
gi|302556750|ref|ZP_07309092.1| thymidylate synthase [Streptomyc... 421 7e-116
gi|317508366|ref|ZP_07966039.1| thymidylate synthase [Segnilipar... 419 3e-115
gi|340793614|ref|YP_004759077.1| Thymidylate synthase [Corynebac... 418 4e-115
gi|333921298|ref|YP_004494879.1| Thymidylate synthase [Amycolici... 416 2e-114
gi|336324919|ref|YP_004604885.1| Thymidylate synthase [Corynebac... 416 2e-114
gi|152968378|ref|YP_001364162.1| Thymidylate synthase [Kineococc... 416 2e-114
>gi|15842302|ref|NP_337339.1| thymidylate synthase [Mycobacterium tuberculosis CDC1551]
gi|294994142|ref|ZP_06799833.1| thymidylate synthase [Mycobacterium tuberculosis 210]
gi|306777045|ref|ZP_07415382.1| thymidylate synthase thyA [Mycobacterium tuberculosis SUMu001]
21 more sequence titles
Length=266
Score = 546 bits (1408), Expect = 8e-154, Method: Compositional matrix adjust.
Identities = 263/263 (100%), Positives = 263/263 (100%), Gaps = 0/263 (0%)
Query 1 VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 60
VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL
Sbjct 4 VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 63
Query 61 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 120
WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR
Sbjct 64 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 123
Query 121 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 180
TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS
Sbjct 124 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 183
Query 181 YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 240
YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE
Sbjct 184 YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 243
Query 241 YTYEDIVVKNYDPHPAIKAPVAV 263
YTYEDIVVKNYDPHPAIKAPVAV
Sbjct 244 YTYEDIVVKNYDPHPAIKAPVAV 266
>gi|340707881|pdb|3QJ7|A Chain A, Crystal Structure Of The Mycobacterium Tuberculosis
Thymidylate Synthase (Thya) Bound To Dump
gi|340707882|pdb|3QJ7|B Chain B, Crystal Structure Of The Mycobacterium Tuberculosis
Thymidylate Synthase (Thya) Bound To Dump
gi|340707883|pdb|3QJ7|C Chain C, Crystal Structure Of The Mycobacterium Tuberculosis
Thymidylate Synthase (Thya) Bound To Dump
gi|340707884|pdb|3QJ7|D Chain D, Crystal Structure Of The Mycobacterium Tuberculosis
Thymidylate Synthase (Thya) Bound To Dump
Length=264
Score = 545 bits (1404), Expect = 2e-153, Method: Compositional matrix adjust.
Identities = 262/263 (99%), Positives = 263/263 (100%), Gaps = 0/263 (0%)
Query 1 VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 60
+TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL
Sbjct 2 MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 61
Query 61 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 120
WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR
Sbjct 62 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 121
Query 121 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 180
TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS
Sbjct 122 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 181
Query 181 YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 240
YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE
Sbjct 182 YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 241
Query 241 YTYEDIVVKNYDPHPAIKAPVAV 263
YTYEDIVVKNYDPHPAIKAPVAV
Sbjct 242 YTYEDIVVKNYDPHPAIKAPVAV 264
>gi|15609901|ref|NP_217280.1| thymidylate synthase [Mycobacterium tuberculosis H37Rv]
gi|31793939|ref|NP_856432.1| thymidylate synthase [Mycobacterium bovis AF2122/97]
gi|121638643|ref|YP_978867.1| thymidylate synthase [Mycobacterium bovis BCG str. Pasteur 1173P2]
45 more sequence titles
Length=263
Score = 545 bits (1404), Expect = 3e-153, Method: Compositional matrix adjust.
Identities = 262/263 (99%), Positives = 263/263 (100%), Gaps = 0/263 (0%)
Query 1 VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 60
+TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL
Sbjct 1 MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 60
Query 61 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 120
WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR
Sbjct 61 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 120
Query 121 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 180
TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS
Sbjct 121 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 180
Query 181 YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 240
YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE
Sbjct 181 YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 240
Query 241 YTYEDIVVKNYDPHPAIKAPVAV 263
YTYEDIVVKNYDPHPAIKAPVAV
Sbjct 241 YTYEDIVVKNYDPHPAIKAPVAV 263
>gi|253798154|ref|YP_003031155.1| thymidylate synthase thyA [Mycobacterium tuberculosis KZN 1435]
gi|297732371|ref|ZP_06961489.1| thymidylate synthase [Mycobacterium tuberculosis KZN R506]
gi|313659703|ref|ZP_07816583.1| thymidylate synthase [Mycobacterium tuberculosis KZN V2475]
gi|253319657|gb|ACT24260.1| thymidylate synthase thyA [Mycobacterium tuberculosis KZN 1435]
Length=266
Score = 545 bits (1404), Expect = 3e-153, Method: Compositional matrix adjust.
Identities = 262/263 (99%), Positives = 262/263 (99%), Gaps = 0/263 (0%)
Query 1 VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 60
VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL
Sbjct 4 VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 63
Query 61 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 120
WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR
Sbjct 64 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 123
Query 121 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 180
TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS
Sbjct 124 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 183
Query 181 YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 240
YALLTHMMAAQAGLSVGEFIW GGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE
Sbjct 184 YALLTHMMAAQAGLSVGEFIWAGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 243
Query 241 YTYEDIVVKNYDPHPAIKAPVAV 263
YTYEDIVVKNYDPHPAIKAPVAV
Sbjct 244 YTYEDIVVKNYDPHPAIKAPVAV 266
>gi|148823952|ref|YP_001288706.1| thymidylate synthase [Mycobacterium tuberculosis F11]
gi|254551823|ref|ZP_05142270.1| thymidylate synthase [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
gi|289553451|ref|ZP_06442661.1| thymidylate synthase thyA [Mycobacterium tuberculosis KZN 605]
7 more sequence titles
Length=263
Score = 543 bits (1399), Expect = 9e-153, Method: Compositional matrix adjust.
Identities = 261/263 (99%), Positives = 262/263 (99%), Gaps = 0/263 (0%)
Query 1 VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 60
+TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL
Sbjct 1 MTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 60
Query 61 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 120
WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR
Sbjct 61 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 120
Query 121 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 180
TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS
Sbjct 121 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 180
Query 181 YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 240
YALLTHMMAAQAGLSVGEFIW GGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE
Sbjct 181 YALLTHMMAAQAGLSVGEFIWAGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 240
Query 241 YTYEDIVVKNYDPHPAIKAPVAV 263
YTYEDIVVKNYDPHPAIKAPVAV
Sbjct 241 YTYEDIVVKNYDPHPAIKAPVAV 263
>gi|41408967|ref|NP_961803.1| thymidylate synthase [Mycobacterium avium subsp. paratuberculosis
K-10]
gi|62901338|sp|Q73VZ2.1|TYSY_MYCPA RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|41397326|gb|AAS05186.1| ThyA [Mycobacterium avium subsp. paratuberculosis K-10]
gi|336458977|gb|EGO37931.1| thymidylate synthase/thymidylate synthase [Mycobacterium avium
subsp. paratuberculosis S397]
Length=266
Score = 506 bits (1304), Expect = 1e-141, Method: Compositional matrix adjust.
Identities = 240/262 (92%), Positives = 251/262 (96%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VL+ GT KSDRTGTGTRSLFGQQ+RYDLSAGFPL+TTKKVH KSV YELLW
Sbjct 5 TPYEDLLRLVLDRGTAKSDRTGTGTRSLFGQQLRYDLSAGFPLITTKKVHLKSVVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WLH HGVTIWDEWASDTG+LGPIYGVQWRSWP PSGEHIDQISAALDLLRT
Sbjct 65 FLRGDSNVDWLHRHGVTIWDEWASDTGDLGPIYGVQWRSWPTPSGEHIDQISAALDLLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRRIIVSAWNVGEI RMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRIIVSAWNVGEIPRMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGLSVGEF+WTGGDCHIYDNHVEQVRLQLSREPRPYP+L+LA RDSIF+Y
Sbjct 185 ALLTHMMAAQAGLSVGEFVWTGGDCHIYDNHVEQVRLQLSREPRPYPELILAHRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TY+D+VV NYDPHPAIKAPVAV
Sbjct 245 TYDDVVVHNYDPHPAIKAPVAV 266
>gi|118465321|ref|YP_882829.1| thymidylate synthase [Mycobacterium avium 104]
gi|254776088|ref|ZP_05217604.1| thymidylate synthase [Mycobacterium avium subsp. avium ATCC 25291]
gi|166231711|sp|A0QIU1.1|TYSY_MYCA1 RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|118166608|gb|ABK67505.1| thymidylate synthase [Mycobacterium avium 104]
Length=266
Score = 506 bits (1303), Expect = 1e-141, Method: Compositional matrix adjust.
Identities = 240/262 (92%), Positives = 251/262 (96%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VL+ GT KSDRTGTGTRSLFGQQ+RYDLSAGFPL+TTKKVH KSV YELLW
Sbjct 5 TPYEDLLRLVLDRGTAKSDRTGTGTRSLFGQQLRYDLSAGFPLITTKKVHLKSVVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WLH HGVTIWDEWASDTG+LGPIYGVQWRSWP PSGEHIDQISAALDLLRT
Sbjct 65 FLRGDSNVDWLHRHGVTIWDEWASDTGDLGPIYGVQWRSWPTPSGEHIDQISAALDLLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRRIIVSAWNVGEI RMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRIIVSAWNVGEIPRMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGLSVGEF+WTGGDCHIYDNHVEQVRLQLSREPRPYP+L+LA RDSIF+Y
Sbjct 185 ALLTHMMAAQAGLSVGEFVWTGGDCHIYDNHVEQVRLQLSREPRPYPELVLAHRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TY+D+VV NYDPHPAIKAPVAV
Sbjct 245 TYDDVVVHNYDPHPAIKAPVAV 266
>gi|342858374|ref|ZP_08715029.1| thymidylate synthase [Mycobacterium colombiense CECT 3035]
gi|342134078|gb|EGT87258.1| thymidylate synthase [Mycobacterium colombiense CECT 3035]
Length=266
Score = 504 bits (1299), Expect = 4e-141, Method: Compositional matrix adjust.
Identities = 236/262 (91%), Positives = 251/262 (96%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VL+ GT KSDRTGTGTRSLFGQQ+RYDL+AGFPLLTTKKVH KSV YELLW
Sbjct 5 TPYEDLLRLVLDQGTAKSDRTGTGTRSLFGQQLRYDLAAGFPLLTTKKVHLKSVIYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WLHEHGVTIWDEWAS TG+LGP+YGVQWRSWP PSGEH+DQISAALDLLRT
Sbjct 65 FLRGDSNVAWLHEHGVTIWDEWASSTGDLGPVYGVQWRSWPTPSGEHVDQISAALDLLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRRIIVSAWNVGEI RMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRIIVSAWNVGEIPRMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQ+GL+VGEF+WTGGDCHIYDNHVEQVRLQLSREPRPYP+L+L RDSIF+Y
Sbjct 185 ALLTHMMAAQSGLAVGEFVWTGGDCHIYDNHVEQVRLQLSREPRPYPELVLGARDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TY+D+VVKNYDPHPAIKAPVAV
Sbjct 245 TYDDVVVKNYDPHPAIKAPVAV 266
>gi|254821236|ref|ZP_05226237.1| thymidylate synthase [Mycobacterium intracellulare ATCC 13950]
Length=266
Score = 500 bits (1287), Expect = 8e-140, Method: Compositional matrix adjust.
Identities = 234/262 (90%), Positives = 251/262 (96%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VL+ GT KSDRTGTGTRSLFG+Q+RYDLSAGFPLLTTKKVH KSV YELLW
Sbjct 5 TPYEDLLRLVLDEGTAKSDRTGTGTRSLFGRQLRYDLSAGFPLLTTKKVHLKSVVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WLHEHGVTIWDEWASD G+LGPIYGVQWRSWP P+GEH+DQISAALDLLRT
Sbjct 65 FLRGDSNVAWLHEHGVTIWDEWASDAGDLGPIYGVQWRSWPTPTGEHVDQISAALDLLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DP+SRRIIVSAWNVGEI +MALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPNSRRIIVSAWNVGEIPQMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQ+GLSVGEF+WTGGDCHIYDNHVEQVRLQLSREPRPYP+L+L +RDSIF+Y
Sbjct 185 ALLTHMMAAQSGLSVGEFVWTGGDCHIYDNHVEQVRLQLSREPRPYPELVLGERDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TY D+VV+NYDPHPAIKAPVAV
Sbjct 245 TYGDVVVRNYDPHPAIKAPVAV 266
>gi|240171163|ref|ZP_04749822.1| thymidylate synthase [Mycobacterium kansasii ATCC 12478]
Length=266
Score = 500 bits (1287), Expect = 9e-140, Method: Compositional matrix adjust.
Identities = 238/262 (91%), Positives = 250/262 (96%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VLETG+ KSDRTGTGTRSLFGQQ+RYDLSAGFPLLTTKKVHFKSVAYELLW
Sbjct 5 TPYEDLLRLVLETGSAKSDRTGTGTRSLFGQQIRYDLSAGFPLLTTKKVHFKSVAYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSNIGWLH+HGVTIWDEWAS+TG+LGPIYGVQWRSWPAPSGEHIDQISAAL+LLRT
Sbjct 65 FLRGDSNIGWLHQHGVTIWDEWASETGDLGPIYGVQWRSWPAPSGEHIDQISAALNLLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRRIIVSAWNVG+I +MALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRIIVSAWNVGDIPQMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQ+ L VGEFIWTGGDCHIYDNHVEQVR QL REPRPYPKL+L RDSIF+Y
Sbjct 185 ALLTHMMAAQSDLDVGEFIWTGGDCHIYDNHVEQVRQQLRREPRPYPKLVLVQRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
YEDI V+NY PHPAIKAPVAV
Sbjct 245 AYEDIHVENYHPHPAIKAPVAV 266
>gi|296171672|ref|ZP_06852886.1| thymidylate synthase [Mycobacterium parascrofulaceum ATCC BAA-614]
gi|295894033|gb|EFG73796.1| thymidylate synthase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=270
Score = 499 bits (1284), Expect = 2e-139, Method: Compositional matrix adjust.
Identities = 233/262 (89%), Positives = 248/262 (95%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
PYEDLLR VLE GT KSDRTGTGTRSLFG Q+RYDLSAGFPLLTTKKVH KSV YELLW
Sbjct 9 APYEDLLRLVLERGTAKSDRTGTGTRSLFGHQLRYDLSAGFPLLTTKKVHLKSVVYELLW 68
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WLHEHGVTIWDEWAS+TG+LGPIYGVQWRSWP PSGEH+DQISAAL+LLRT
Sbjct 69 FLRGDSNVAWLHEHGVTIWDEWASETGDLGPIYGVQWRSWPTPSGEHVDQISAALELLRT 128
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DP+SRRIIVSAWNVGEI +M LPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 129 DPNSRRIIVSAWNVGEIPQMVLPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 188
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGLSVGEF+WTGGDCHIYDNHVEQVR QL REPRPYP+L+LA RDSIF+Y
Sbjct 189 ALLTHMMAAQAGLSVGEFVWTGGDCHIYDNHVEQVRTQLGREPRPYPELVLAQRDSIFDY 248
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TY+D+V+KNYDPHPAIKAPVAV
Sbjct 249 TYDDVVIKNYDPHPAIKAPVAV 270
>gi|118617725|ref|YP_906057.1| thymidylate synthase [Mycobacterium ulcerans Agy99]
gi|166231717|sp|A0PQG7.1|TYSY_MYCUA RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|118569835|gb|ABL04586.1| thymidylate synthase ThyA [Mycobacterium ulcerans Agy99]
Length=266
Score = 498 bits (1282), Expect = 3e-139, Method: Compositional matrix adjust.
Identities = 236/262 (91%), Positives = 249/262 (96%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VLETGT KSDRTGTGTRSLFGQQ+RYDL GFPLLTTKKVHFKSV YELLW
Sbjct 5 TPYEDLLRRVLETGTAKSDRTGTGTRSLFGQQIRYDLGCGFPLLTTKKVHFKSVVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+GWL +HGVTIWDEWAS+TG+LGPIYGVQWRSWP PSGEHIDQISAAL+LLRT
Sbjct 65 FLRGDSNVGWLQQHGVTIWDEWASETGDLGPIYGVQWRSWPTPSGEHIDQISAALELLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRRIIVSAWNVG+I +MALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRIIVSAWNVGQIPQMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQV QL REPRPYPKL L+ RDSIF+Y
Sbjct 185 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVTEQLRREPRPYPKLSLSQRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TYED+VV++YDPHPAIKAPVAV
Sbjct 245 TYEDVVVQDYDPHPAIKAPVAV 266
>gi|183981970|ref|YP_001850261.1| thymidylate synthase ThyA [Mycobacterium marinum M]
gi|183175296|gb|ACC40406.1| thymidylate synthase ThyA [Mycobacterium marinum M]
Length=266
Score = 495 bits (1275), Expect = 2e-138, Method: Compositional matrix adjust.
Identities = 235/262 (90%), Positives = 248/262 (95%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VLETGT KSDRTGTGTRSLFGQQ+RYDL GFPLLTTKKVHFKSV YELLW
Sbjct 5 TPYEDLLRRVLETGTAKSDRTGTGTRSLFGQQIRYDLGCGFPLLTTKKVHFKSVVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+GWL +HGVTIWDEWAS+TG+LGPIYGVQWRSWP PSGEHIDQISAAL+LLRT
Sbjct 65 FLRGDSNVGWLQQHGVTIWDEWASETGDLGPIYGVQWRSWPTPSGEHIDQISAALELLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRRIIVSAWNVG+I +MALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRIIVSAWNVGQIPQMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGLSVGEFIWTGGDCHIY NHVEQV QL REPRPYPKL L+ RDSIF+Y
Sbjct 185 ALLTHMMAAQAGLSVGEFIWTGGDCHIYGNHVEQVTEQLRREPRPYPKLSLSQRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TYED+VV++YDPHPAIKAPVAV
Sbjct 245 TYEDVVVQDYDPHPAIKAPVAV 266
>gi|108799079|ref|YP_639276.1| thymidylate synthase [Mycobacterium sp. MCS]
gi|119868194|ref|YP_938146.1| thymidylate synthase [Mycobacterium sp. KMS]
gi|126434685|ref|YP_001070376.1| thymidylate synthase [Mycobacterium sp. JLS]
6 more sequence titles
Length=266
Score = 493 bits (1268), Expect = 2e-137, Method: Compositional matrix adjust.
Identities = 231/262 (89%), Positives = 246/262 (94%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR V E GTPKSDRTGTGTRSLFG QMRYDL+AGFPL+TTKKVH KSV YELLW
Sbjct 5 TPYEDLLRLVFERGTPKSDRTGTGTRSLFGHQMRYDLAAGFPLITTKKVHLKSVVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRG+SN+ WL EHGVTIWDEWAS+TGELGP+YGVQWRSWP PSG H+DQISAA+DLLRT
Sbjct 65 FLRGESNVRWLQEHGVTIWDEWASETGELGPVYGVQWRSWPTPSGGHVDQISAAVDLLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR IVSAWNVGEI +MALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRNIVSAWNVGEIPQMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGL VGEF+WTGGDCHIYDNHVEQV QLSR+PRPYP+L+LA RDSIF+Y
Sbjct 185 ALLTHMMAAQAGLGVGEFVWTGGDCHIYDNHVEQVTEQLSRDPRPYPELVLAQRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TYED+VVKNYDPHPAIKAPVAV
Sbjct 245 TYEDVVVKNYDPHPAIKAPVAV 266
>gi|118467946|ref|YP_887007.1| thymidylate synthase [Mycobacterium smegmatis str. MC2 155]
gi|166231713|sp|A0QVR9.1|TYSY_MYCS2 RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|118169233|gb|ABK70129.1| thymidylate synthase [Mycobacterium smegmatis str. MC2 155]
Length=266
Score = 489 bits (1259), Expect = 2e-136, Method: Compositional matrix adjust.
Identities = 231/262 (89%), Positives = 245/262 (94%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR V E GTPKSDRTGTGTRSLFG QMRYDLSAGFPL+TTKKVH KSV YELLW
Sbjct 5 TPYEDLLRLVTERGTPKSDRTGTGTRSLFGHQMRYDLSAGFPLITTKKVHTKSVIYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL EHGVTIWDEWAS+TG+LGPIYGVQWRSWP PSGEHIDQIS+AL+LL++
Sbjct 65 FLRGDSNVRWLQEHGVTIWDEWASETGDLGPIYGVQWRSWPTPSGEHIDQISSALELLKS 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR IVSAWNVGEI +MALPPCHAFFQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRNIVSAWNVGEIPQMALPPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGL VGEFIWTGGDCHIYDNH EQV LQLSREPRPYP+L+LA RDSIF+Y
Sbjct 185 ALLTHMMAAQAGLDVGEFIWTGGDCHIYDNHTEQVALQLSREPRPYPELVLAPRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TYEDI + NYDPHPAIKAPVAV
Sbjct 245 TYEDIAIVNYDPHPAIKAPVAV 266
>gi|145224587|ref|YP_001135265.1| thymidylate synthase [Mycobacterium gilvum PYR-GCK]
gi|189036939|sp|A4TCI9.1|TYSY_MYCGI RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|145217073|gb|ABP46477.1| thymidylate synthase [Mycobacterium gilvum PYR-GCK]
Length=266
Score = 488 bits (1256), Expect = 4e-136, Method: Compositional matrix adjust.
Identities = 229/262 (88%), Positives = 246/262 (94%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VL+TGTPKSDRTGTGTRSLFG QMRYDL+AGFPL+TTKKVH KS+ YELLW
Sbjct 5 TPYEDLLRLVLDTGTPKSDRTGTGTRSLFGHQMRYDLNAGFPLITTKKVHTKSIVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL E GVTIWDEWAS TG+LGP+YGVQWRSWP PSGEHIDQISAALDLL+
Sbjct 65 FLRGDSNVRWLQERGVTIWDEWASPTGDLGPVYGVQWRSWPTPSGEHIDQISAALDLLKR 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR IVSAWNVGEI +MALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRNIVSAWNVGEIPQMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGL VGEFIWTGGDCHIYDNHVEQV QLSR+PRPYP+L+LA RDSIF+Y
Sbjct 185 ALLTHMMAAQAGLGVGEFIWTGGDCHIYDNHVEQVTEQLSRDPRPYPELVLAPRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TYED+V+KNY+PHPAIKAPVA+
Sbjct 245 TYEDVVIKNYEPHPAIKAPVAI 266
>gi|315444918|ref|YP_004077797.1| thymidylate synthase [Mycobacterium sp. Spyr1]
gi|315263221|gb|ADT99962.1| thymidylate synthase [Mycobacterium sp. Spyr1]
Length=266
Score = 487 bits (1254), Expect = 6e-136, Method: Compositional matrix adjust.
Identities = 229/262 (88%), Positives = 246/262 (94%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VL+TGTPKSDRTGTGTRSLFG QMRYDL+AGFPL+TTKKVH KS+ YELLW
Sbjct 5 TPYEDLLRLVLDTGTPKSDRTGTGTRSLFGHQMRYDLNAGFPLITTKKVHTKSIVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL E GVTIWDEWAS TG+LGP+YGVQWRSWP PSGEHIDQISAALDLL+
Sbjct 65 FLRGDSNVRWLQERGVTIWDEWASPTGDLGPVYGVQWRSWPTPSGEHIDQISAALDLLKH 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR IVSAWNVGEI +MALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRNIVSAWNVGEIPQMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGL VGEFIWTGGDCHIYDNHVEQV QLSR+PRPYP+L+LA RDSIF+Y
Sbjct 185 ALLTHMMAAQAGLGVGEFIWTGGDCHIYDNHVEQVTEQLSRDPRPYPELVLAPRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TYED+V+KNY+PHPAIKAPVA+
Sbjct 245 TYEDVVIKNYEPHPAIKAPVAI 266
>gi|120403371|ref|YP_953200.1| thymidylate synthase [Mycobacterium vanbaalenii PYR-1]
gi|166231718|sp|A1T7P4.1|TYSY_MYCVP RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|119956189|gb|ABM13194.1| thymidylate synthase [Mycobacterium vanbaalenii PYR-1]
Length=266
Score = 484 bits (1245), Expect = 6e-135, Method: Compositional matrix adjust.
Identities = 228/262 (88%), Positives = 243/262 (93%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VL+TGT KSDRTGTGTRSLFG QMRYDL+AGFPL+TTKKVH KS+ YELLW
Sbjct 5 TPYEDLLRLVLDTGTTKSDRTGTGTRSLFGHQMRYDLNAGFPLITTKKVHTKSIVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL EHGVTIWDEWAS TG+LGP+YGVQWRSWP PSG HIDQISAALDLLR
Sbjct 65 FLRGDSNVRWLQEHGVTIWDEWASPTGDLGPVYGVQWRSWPTPSGAHIDQISAALDLLRR 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR IVSAWNVGEI +MALPPCHAFFQFYV+ GRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRNIVSAWNVGEIPQMALPPCHAFFQFYVSGGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGL VGEFIWTGGDCHIYDNHVEQV QLSREPRPYP+L+LA RDS+F+Y
Sbjct 185 ALLTHMMAAQAGLGVGEFIWTGGDCHIYDNHVEQVTEQLSREPRPYPELVLAQRDSLFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
YED+V+KNYDPHPAIKAPVAV
Sbjct 245 IYEDVVIKNYDPHPAIKAPVAV 266
>gi|15827801|ref|NP_302064.1| thymidylate synthase [Mycobacterium leprae TN]
gi|221230278|ref|YP_002503694.1| thymidylate synthase [Mycobacterium leprae Br4923]
gi|15214323|sp|Q9CBW0.1|TYSY_MYCLE RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|13093353|emb|CAC30470.1| thymidylate synthase [Mycobacterium leprae]
gi|219933385|emb|CAR71614.1| thymidylate synthase [Mycobacterium leprae Br4923]
Length=266
Score = 482 bits (1241), Expect = 2e-134, Method: Compositional matrix adjust.
Identities = 224/262 (86%), Positives = 241/262 (92%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VL+ G K DRTGTGTRSLFGQQ+RYDLS GFPL+TTKKVHFKSV YELLW
Sbjct 5 TPYEDLLRLVLDCGVAKMDRTGTGTRSLFGQQLRYDLSVGFPLVTTKKVHFKSVVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WLHEHGV IWDEWAS TG+LGPIYGVQWRSWP SG++IDQIS ALDLLRT
Sbjct 65 FLRGDSNVAWLHEHGVNIWDEWASSTGDLGPIYGVQWRSWPTSSGDYIDQISTALDLLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRRIIVSAWNVGEI +MALPPCHAFFQFYVA GRLSCQLYQRSAD+FLGVPFNIASY
Sbjct 125 EPDSRRIIVSAWNVGEIPQMALPPCHAFFQFYVAQGRLSCQLYQRSADMFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQ+GL VGEF+WTGGDCHIYDNHVEQV+LQLSREPR YP+L LA RDSIF+Y
Sbjct 185 ALLTHMMAAQSGLLVGEFVWTGGDCHIYDNHVEQVQLQLSREPRAYPELFLAQRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
YED+VV NYDPHPAIKAPVA+
Sbjct 245 VYEDVVVTNYDPHPAIKAPVAI 266
>gi|333991150|ref|YP_004523764.1| thymidylate synthase ThyA [Mycobacterium sp. JDM601]
gi|333487118|gb|AEF36510.1| thymidylate synthase ThyA [Mycobacterium sp. JDM601]
Length=266
Score = 470 bits (1210), Expect = 8e-131, Method: Compositional matrix adjust.
Identities = 221/262 (85%), Positives = 239/262 (92%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLL VLE GTPK+DRTGTGTRSLFG Q+RYDL+AGFPL+TTKKVH KSV YELLW
Sbjct 5 TPYEDLLALVLERGTPKADRTGTGTRSLFGHQLRYDLAAGFPLITTKKVHVKSVVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSNI WL EHGV+IWDEWASDTG+LGP+YGVQWRSWP PSG+HIDQI A++LLRT
Sbjct 65 FLRGDSNIAWLKEHGVSIWDEWASDTGDLGPVYGVQWRSWPTPSGQHIDQIERAVELLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRRIIVSAWNVGE+++MAL PCHA FQFYVA GRLSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRIIVSAWNVGELDQMALAPCHALFQFYVAGGRLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGL VGEF+WTGGDCHIYDNHVEQVR QLSR+PR YPKL LA RDSIF Y
Sbjct 185 ALLTHMMAAQAGLDVGEFVWTGGDCHIYDNHVEQVREQLSRQPRGYPKLALAPRDSIFGY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
T++DI + YDPHPAIKAPVAV
Sbjct 245 TFDDIEILGYDPHPAIKAPVAV 266
>gi|169630173|ref|YP_001703822.1| thymidylate synthase ThyA [Mycobacterium abscessus ATCC 19977]
gi|169242140|emb|CAM63168.1| Thymidylate synthase (ThyA) [Mycobacterium abscessus]
Length=266
Score = 463 bits (1191), Expect = 1e-128, Method: Compositional matrix adjust.
Identities = 218/262 (84%), Positives = 236/262 (91%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VLE GTPK+DRTGTGTRS+FG Q+RY L GFPL+TTKKVH KSV YELLW
Sbjct 5 TPYEDLLRLVLEEGTPKADRTGTGTRSVFGHQLRYRLEDGFPLITTKKVHLKSVIYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRG+SN+ WL E GVTIWDEWAS+ GELGP+YGVQWR+WP PSGEHIDQISAALDLLRT
Sbjct 65 FLRGESNVRWLQERGVTIWDEWASEAGELGPVYGVQWRAWPTPSGEHIDQISAALDLLRT 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRR IVSAWNVGEI +MALPPCHAFFQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 125 NPDSRRNIVSAWNVGEIPQMALPPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMAAQAGL VG+F+WTGGDCHIYDNHVEQV QLSR+P PYP L+LA RDSIF+Y
Sbjct 185 ALLTHMMAAQAGLGVGDFVWTGGDCHIYDNHVEQVTEQLSRDPYPYPTLVLAQRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
YEDI V+NY H AIKAPVAV
Sbjct 245 RYEDITVENYQHHAAIKAPVAV 266
>gi|262202109|ref|YP_003273317.1| thymidylate synthase [Gordonia bronchialis DSM 43247]
gi|262085456|gb|ACY21424.1| thymidylate synthase [Gordonia bronchialis DSM 43247]
Length=270
Score = 460 bits (1184), Expect = 7e-128, Method: Compositional matrix adjust.
Identities = 218/262 (84%), Positives = 233/262 (89%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLL VLETGTPK DRTGTGTRSLFG Q+RYDL+AGFPL+TTKKVH KS+ YELLW
Sbjct 9 TPYEDLLALVLETGTPKDDRTGTGTRSLFGHQLRYDLAAGFPLITTKKVHLKSIIYELLW 68
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL E GVTIWDEWA D GELGP+YGVQWRSWP PSGEHIDQI+ AL LLRT
Sbjct 69 FLRGDSNVRWLQERGVTIWDEWADDNGELGPVYGVQWRSWPTPSGEHIDQIAGALRLLRT 128
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR IVSAWNVGEI +MALPPCHAFFQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 129 DPDSRRNIVSAWNVGEIPQMALPPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 188
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMA QAGL VGEF+WTGGDCHIYDNHV+QVRLQLSR+P PYPKL L RDSIF Y
Sbjct 189 ALLTHMMAQQAGLGVGEFVWTGGDCHIYDNHVDQVRLQLSRDPYPYPKLELRHRDSIFGY 248
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
++DI V +Y HP IKAPVAV
Sbjct 249 EFDDIAVVDYRSHPPIKAPVAV 270
>gi|343927028|ref|ZP_08766516.1| thymidylate synthase [Gordonia alkanivorans NBRC 16433]
gi|343763086|dbj|GAA13442.1| thymidylate synthase [Gordonia alkanivorans NBRC 16433]
Length=287
Score = 460 bits (1184), Expect = 9e-128, Method: Compositional matrix adjust.
Identities = 214/262 (82%), Positives = 233/262 (89%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VLETGTPK+DRTGTGTRSLFG Q+RYDL+ GFPL+TTKKVH KS+ YELLW
Sbjct 26 TPYEDLLRLVLETGTPKADRTGTGTRSLFGHQLRYDLAEGFPLITTKKVHLKSIIYELLW 85
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL E GVTIWDEWA GELGP+YGVQWRSWP PSGE IDQISAAL++L+T
Sbjct 86 FLRGDSNVRWLQERGVTIWDEWADTNGELGPVYGVQWRSWPTPSGEQIDQISAALEMLKT 145
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRR IVSAWNVGEI +MALPPCHAFFQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 146 NPDSRRNIVSAWNVGEIPQMALPPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 205
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMA QAGL VGEF+WTGGDCHIYDNH++QV LQLSREP PYPKL L RDSIF+Y
Sbjct 206 ALLTHMMAQQAGLEVGEFVWTGGDCHIYDNHLDQVNLQLSREPYPYPKLELRKRDSIFDY 265
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
Y+DI + Y HP IKAPVAV
Sbjct 266 EYDDIEIVGYQSHPGIKAPVAV 287
>gi|326384524|ref|ZP_08206204.1| thymidylate synthase [Gordonia neofelifaecis NRRL B-59395]
gi|326196869|gb|EGD54063.1| thymidylate synthase [Gordonia neofelifaecis NRRL B-59395]
Length=268
Score = 445 bits (1144), Expect = 4e-123, Method: Compositional matrix adjust.
Identities = 207/262 (80%), Positives = 231/262 (89%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VLETGTPK+DRTGTGTRS+FG QMR+DLS GFP++TTKKVH KS+ YELLW
Sbjct 7 TPYEDLLRLVLETGTPKADRTGTGTRSVFGHQMRFDLSEGFPVITTKKVHLKSIIYELLW 66
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL + GVTIWDEWAS GELGP+YGVQWR+WP PSGEH+DQI+ AL+ LR+
Sbjct 67 FLRGDSNVRWLQDRGVTIWDEWASPEGELGPVYGVQWRNWPTPSGEHVDQIAVALETLRS 126
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR IVSAWNVGEI +MALPPCHAFFQFYVA G+LSCQLYQRSADLFLGVPFNIASY
Sbjct 127 DPDSRRNIVSAWNVGEIPQMALPPCHAFFQFYVAGGKLSCQLYQRSADLFLGVPFNIASY 186
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMA QAGL VG+F+WTGGDCHIYDNHVEQVR QLSR+ PYP L L DSIF+Y
Sbjct 187 ALLTHMMAQQAGLEVGDFVWTGGDCHIYDNHVEQVREQLSRDALPYPTLRLRKADSIFDY 246
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
++D+ V +Y HPAIKAPVAV
Sbjct 247 DFDDVEVVDYHSHPAIKAPVAV 268
>gi|226307948|ref|YP_002767908.1| thymidylate synthase [Rhodococcus erythropolis PR4]
gi|229495127|ref|ZP_04388873.1| thymidylate synthase [Rhodococcus erythropolis SK121]
gi|226187065|dbj|BAH35169.1| thymidylate synthase [Rhodococcus erythropolis PR4]
gi|229318058|gb|EEN83933.1| thymidylate synthase [Rhodococcus erythropolis SK121]
Length=266
Score = 445 bits (1144), Expect = 4e-123, Method: Compositional matrix adjust.
Identities = 203/262 (78%), Positives = 229/262 (88%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
T YEDLLR V+ETGT KSDRTGTGTRS+FG QMR+DL+ GFPL+TTKKVH KS+ ELLW
Sbjct 5 TAYEDLLRLVMETGTAKSDRTGTGTRSIFGHQMRFDLADGFPLVTTKKVHLKSIVNELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WLHEHGV+IWDEWA + GELGP+YGVQWRSWP PSGEHIDQI+ ++ LR+
Sbjct 65 FLRGDSNVAWLHEHGVSIWDEWADENGELGPVYGVQWRSWPTPSGEHIDQITQTVETLRS 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRRIIVSAWNV +I +MAL PCHAFFQFYVADG+LSCQLYQRSAD+FLGVPFNIASY
Sbjct 125 NPDSRRIIVSAWNVADIPQMALAPCHAFFQFYVADGKLSCQLYQRSADMFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMA QAGL VGEF+WTGGDCHIYDNHV+QV QL REP P P L L RDSIF+Y
Sbjct 185 ALLTHMMAQQAGLDVGEFVWTGGDCHIYDNHVDQVTEQLGREPLPLPTLKLNKRDSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
T+ED+ + +Y HPAIKAPVAV
Sbjct 245 TFEDVEIVDYQHHPAIKAPVAV 266
>gi|296139474|ref|YP_003646717.1| thymidylate synthase [Tsukamurella paurometabola DSM 20162]
gi|296027608|gb|ADG78378.1| thymidylate synthase [Tsukamurella paurometabola DSM 20162]
Length=265
Score = 442 bits (1138), Expect = 2e-122, Method: Compositional matrix adjust.
Identities = 207/263 (79%), Positives = 229/263 (88%), Gaps = 0/263 (0%)
Query 1 VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 60
TPYEDLLR VL GT + DRTGTGTRS+FG+Q+RYDLS GFPL+TTK+VH KS+AYELL
Sbjct 3 ATPYEDLLRDVLANGTHRPDRTGTGTRSVFGRQLRYDLSEGFPLITTKRVHMKSIAYELL 62
Query 61 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 120
WFLRGDSN+ WL EHGVTIWDEWA GELGP+YGVQWRSWP P+GEHIDQI+ A++LL+
Sbjct 63 WFLRGDSNVRWLQEHGVTIWDEWADANGELGPVYGVQWRSWPTPNGEHIDQIATAIELLK 122
Query 121 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 180
TDP SRR IVSAWNV EIE MALPPCHAFFQFY ADG+LSCQLYQRSADLFLGVPFNIAS
Sbjct 123 TDPSSRRNIVSAWNVSEIENMALPPCHAFFQFYAADGKLSCQLYQRSADLFLGVPFNIAS 182
Query 181 YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 240
YALLTHM+AAQ GL G+F+WTGGDCHIYDNHVEQV QLSREP PYP+L LA+R SIF+
Sbjct 183 YALLTHMVAAQVGLEPGDFVWTGGDCHIYDNHVEQVTEQLSREPYPYPRLELAERPSIFD 242
Query 241 YTYEDIVVKNYDPHPAIKAPVAV 263
Y Y DI V +Y HPAIKAPVAV
Sbjct 243 YEYGDITVHDYQHHPAIKAPVAV 265
>gi|319950119|ref|ZP_08024059.1| thymidylate synthase [Dietzia cinnamea P4]
gi|319436222|gb|EFV91402.1| thymidylate synthase [Dietzia cinnamea P4]
Length=266
Score = 442 bits (1137), Expect = 3e-122, Method: Compositional matrix adjust.
Identities = 207/262 (80%), Positives = 227/262 (87%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLL+ VLE G PK+DRTGTGTRSLFG Q+RYDL+ GFPL+TTK+VHFKSVAYELLW
Sbjct 5 TPYEDLLQLVLEQGAPKADRTGTGTRSLFGHQLRYDLAQGFPLITTKRVHFKSVAYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+GWL E+GVTIWDEWA GELGP+YGVQWRSWP P G HIDQI+AA++LLR
Sbjct 65 FLRGDSNVGWLRENGVTIWDEWADADGELGPVYGVQWRSWPTPDGAHIDQIAAAVELLRA 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR IVSAWNV E+ MALPPCH FQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 125 DPDSRRNIVSAWNVSELSEMALPPCHLLFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
+LLTHM+A Q GL VGEFIWTGGDCHIYDNHVEQVR QLSREP PYP+L L SIF+Y
Sbjct 185 SLLTHMIAQQVGLEVGEFIWTGGDCHIYDNHVEQVRTQLSREPYPYPELRLNRAPSIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
T+ED V Y+ HP IKAPVAV
Sbjct 245 TFEDFEVVGYEHHPGIKAPVAV 266
>gi|334338011|ref|YP_004543163.1| Thymidylate synthase [Isoptericola variabilis 225]
gi|334108379|gb|AEG45269.1| Thymidylate synthase [Isoptericola variabilis 225]
Length=274
Score = 441 bits (1134), Expect = 6e-122, Method: Compositional matrix adjust.
Identities = 204/262 (78%), Positives = 227/262 (87%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VLETGT KSDRTGTGTRS+FG+Q+RYDL GFPL+TTK+VH KSV YELLW
Sbjct 13 TPYEDLLREVLETGTRKSDRTGTGTRSVFGRQLRYDLQQGFPLVTTKRVHLKSVVYELLW 72
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL EHGVTIWDEWA+ GELGP+YGVQWRSWP P G H+DQI +D +R
Sbjct 73 FLRGDSNVRWLQEHGVTIWDEWAAPDGELGPVYGVQWRSWPTPDGRHVDQIQGVIDQIRV 132
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRR+IVSAWNV E+ MALPPCH FQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 133 NPDSRRLIVSAWNVAELADMALPPCHLLFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 192
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+AAQ GL VGEF+WTGGDCH+Y+NHVEQV QL R+P PYP L LA R SIF+Y
Sbjct 193 ALLTHMVAAQTGLDVGEFVWTGGDCHVYENHVEQVETQLGRDPYPYPTLRLAPRGSIFDY 252
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TYED+VV+NY HPAIKAPVAV
Sbjct 253 TYEDVVVENYQHHPAIKAPVAV 274
>gi|325676379|ref|ZP_08156058.1| thymidylate synthase [Rhodococcus equi ATCC 33707]
gi|325552940|gb|EGD22623.1| thymidylate synthase [Rhodococcus equi ATCC 33707]
Length=264
Score = 439 bits (1130), Expect = 2e-121, Method: Compositional matrix adjust.
Identities = 201/262 (77%), Positives = 230/262 (88%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
+PYEDLLR V++TGT K+DRTGTGTRS+FG QMR+DL+ GFPL+TTKKVH KS+ YELLW
Sbjct 3 SPYEDLLRLVMDTGTAKADRTGTGTRSVFGHQMRWDLAEGFPLITTKKVHLKSIVYELLW 62
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRG+SN+ WL EHGVTIWDEWA GELGP+YGVQWRSWP PSGEHIDQI+ ++ L+T
Sbjct 63 FLRGESNVKWLQEHGVTIWDEWADADGELGPVYGVQWRSWPTPSGEHIDQITKVVETLKT 122
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRRIIVSAWNV +++ MAL PCHAFFQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 123 NPDSRRIIVSAWNVADLDAMALQPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 182
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+A QA L VG+FIWTGGDCHIYDNHV+QV QLSREP PYP L L RDSIF+Y
Sbjct 183 ALLTHMVAQQADLEVGDFIWTGGDCHIYDNHVDQVTEQLSREPLPYPTLKLNKRDSIFDY 242
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
T+ED+ + +Y HPAIKAPVAV
Sbjct 243 TFEDVEIVDYRHHPAIKAPVAV 264
>gi|226361376|ref|YP_002779154.1| thymidylate synthase [Rhodococcus opacus B4]
gi|226239861|dbj|BAH50209.1| thymidylate synthase [Rhodococcus opacus B4]
Length=267
Score = 439 bits (1130), Expect = 2e-121, Method: Compositional matrix adjust.
Identities = 202/262 (78%), Positives = 232/262 (89%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR V++TGTPK+DRTGTGTRS+FG QMR++L+ GFPL+TTKKVH KS+ YELLW
Sbjct 6 TPYEDLLRLVMDTGTPKADRTGTGTRSVFGHQMRWNLADGFPLVTTKKVHLKSIVYELLW 65
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL ++GVTIWDEWA GELGP+YGVQWRSWP PSGEHIDQIS ++ L++
Sbjct 66 FLRGDSNVKWLQDNGVTIWDEWADADGELGPVYGVQWRSWPTPSGEHIDQISQTIETLKS 125
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRRIIVSAWNVG+I +MAL PCHAFFQFYVADG+LSCQLYQRSAD+FLGVPFNIASY
Sbjct 126 NPDSRRIIVSAWNVGDIPQMALAPCHAFFQFYVADGKLSCQLYQRSADMFLGVPFNIASY 185
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+A QAGL G+FIWTGGDCHIYDNHV+QV QLSREP PYP L L RDSIF+Y
Sbjct 186 ALLTHMVAQQAGLEPGDFIWTGGDCHIYDNHVDQVAEQLSREPLPYPTLKLNRRDSIFDY 245
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
T+ED+ + +Y HPAIKAPVAV
Sbjct 246 TFEDVEIVDYRHHPAIKAPVAV 267
>gi|312138557|ref|YP_004005893.1| thymidylate synthase [Rhodococcus equi 103S]
gi|311887896|emb|CBH47208.1| thymidylate synthase [Rhodococcus equi 103S]
Length=273
Score = 439 bits (1128), Expect = 3e-121, Method: Compositional matrix adjust.
Identities = 201/262 (77%), Positives = 230/262 (88%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
+PYEDLLR V++TGT K+DRTGTGTRS+FG QMR+DL+ GFPL+TTKKVH KS+ YELLW
Sbjct 12 SPYEDLLRLVMDTGTAKADRTGTGTRSVFGHQMRWDLAEGFPLITTKKVHLKSIVYELLW 71
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRG+SN+ WL EHGVTIWDEWA GELGP+YGVQWRSWP PSGEHIDQI+ ++ L+T
Sbjct 72 FLRGESNVKWLQEHGVTIWDEWADADGELGPVYGVQWRSWPTPSGEHIDQITKVIETLKT 131
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRRIIVSAWNV +++ MAL PCHAFFQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 132 NPDSRRIIVSAWNVADLDAMALQPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 191
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+A QA L VG+FIWTGGDCHIYDNHV+QV QLSREP PYP L L RDSIF+Y
Sbjct 192 ALLTHMVAQQADLEVGDFIWTGGDCHIYDNHVDQVTEQLSREPLPYPTLKLNKRDSIFDY 251
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
T+ED+ + +Y HPAIKAPVAV
Sbjct 252 TFEDVEIVDYRHHPAIKAPVAV 273
>gi|111019241|ref|YP_702213.1| thymidylate synthase [Rhodococcus jostii RHA1]
gi|123046371|sp|Q0SEI1.1|TYSY_RHOSR RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|110818771|gb|ABG94055.1| thymidylate synthase [Rhodococcus jostii RHA1]
Length=266
Score = 437 bits (1124), Expect = 8e-121, Method: Compositional matrix adjust.
Identities = 200/262 (77%), Positives = 232/262 (89%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR V++TGTPK+DRTGTGT+S+FG QMR++L+ GFPL+TTKKVH KS+ YELLW
Sbjct 5 TPYEDLLRLVMDTGTPKADRTGTGTKSVFGHQMRWNLADGFPLITTKKVHLKSIVYELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL ++GVTIWDEWA GELGP+YGVQWRSWP PSGEHIDQI+ ++ L++
Sbjct 65 FLRGDSNVKWLQDNGVTIWDEWADADGELGPVYGVQWRSWPTPSGEHIDQITQTIETLKS 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRRIIVSAWNVG+I +MAL PCHAFFQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 125 NPDSRRIIVSAWNVGDIPQMALAPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+A QAGL G+FIWTGGDCHIYDNHV+QV QLSREP PYP L L R+SIF+Y
Sbjct 185 ALLTHMVAQQAGLEPGDFIWTGGDCHIYDNHVDQVTEQLSREPLPYPTLKLNKRESIFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
T+ED+ + +Y HPAIKAPVAV
Sbjct 245 TFEDVEIVDYRHHPAIKAPVAV 266
>gi|213964887|ref|ZP_03393086.1| thymidylate synthase [Corynebacterium amycolatum SK46]
gi|213952423|gb|EEB63806.1| thymidylate synthase [Corynebacterium amycolatum SK46]
Length=278
Score = 434 bits (1117), Expect = 5e-120, Method: Compositional matrix adjust.
Identities = 200/262 (77%), Positives = 222/262 (85%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR +L G KSDRTGTGTRS+FG+Q+R+DLS GFPL+TTKKVH KS+ YELLW
Sbjct 17 TPYEDLLREILADGAAKSDRTGTGTRSVFGRQLRFDLSEGFPLITTKKVHLKSIVYELLW 76
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL + GVTIWDEWA D G+LGP+YGVQWRSWP P G HIDQI+ AL+ L++
Sbjct 77 FLRGDSNVRWLQDRGVTIWDEWADDDGDLGPVYGVQWRSWPTPDGHHIDQIAQALETLKS 136
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRR IVSAWNV EI MALPPCH FQFYVADG+LSCQLYQRSAD+FLGVPFNIASY
Sbjct 137 NPDSRRNIVSAWNVSEISNMALPPCHLLFQFYVADGKLSCQLYQRSADMFLGVPFNIASY 196
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMA QAGL VGEFIWTGGDCHIYDNH+EQ LQ+SREPRPYP L L DSIF+Y
Sbjct 197 ALLTHMMAQQAGLDVGEFIWTGGDCHIYDNHIEQCELQVSREPRPYPTLKLRKADSIFDY 256
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
YEDI V YDPHP I+ VAV
Sbjct 257 AYEDIEVIGYDPHPLIRGQVAV 278
>gi|300785995|ref|YP_003766286.1| thymidylate synthase [Amycolatopsis mediterranei U32]
gi|299795509|gb|ADJ45884.1| thymidylate synthase [Amycolatopsis mediterranei U32]
gi|340527461|gb|AEK42666.1| thymidylate synthase [Amycolatopsis mediterranei S699]
Length=265
Score = 434 bits (1115), Expect = 7e-120, Method: Compositional matrix adjust.
Identities = 201/262 (77%), Positives = 227/262 (87%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
T YEDLLR VL+TG K DRTGTGTRS+FG Q+RY LS GFPL+TTKKVHF+S+AYELLW
Sbjct 4 TQYEDLLRHVLDTGARKGDRTGTGTRSIFGHQLRYRLSEGFPLITTKKVHFRSIAYELLW 63
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGD+N+ WL EHGVTIWDEWA++ G+LGP+YGVQWRSWP P G H+DQI+ L LR
Sbjct 64 FLRGDANVSWLREHGVTIWDEWAAEDGDLGPVYGVQWRSWPTPDGGHVDQIAEVLRTLRE 123
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRRIIVSAWNV +I RMALPPCHAFFQF+VADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 124 NPDSRRIIVSAWNVADIPRMALPPCHAFFQFHVADGKLSCQLYQRSADLFLGVPFNIASY 183
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTH++AAQ GL VG+FIWTGGDCHIYDNHV+QVR QL+RE RP+P L L DS+FEY
Sbjct 184 ALLTHLIAAQVGLGVGDFIWTGGDCHIYDNHVDQVRTQLAREARPFPTLGLKPADSLFEY 243
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TYE V+ YDPHP IKAPVAV
Sbjct 244 TYEHFSVEGYDPHPGIKAPVAV 265
>gi|54026996|ref|YP_121238.1| thymidylate synthase [Nocardia farcinica IFM 10152]
gi|62901241|sp|Q5YPL7.1|TYSY_NOCFA RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|54018504|dbj|BAD59874.1| putative thymidylate synthase [Nocardia farcinica IFM 10152]
Length=266
Score = 432 bits (1112), Expect = 2e-119, Method: Compositional matrix adjust.
Identities = 203/260 (79%), Positives = 222/260 (86%), Gaps = 0/260 (0%)
Query 4 YEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLWFL 63
YEDLLR VL+TGT K DRTGTGTRS+FG Q+RYDLSAGFPL+TTKKVH KS+ YELLWFL
Sbjct 7 YEDLLRLVLDTGTAKGDRTGTGTRSIFGHQLRYDLSAGFPLITTKKVHLKSIVYELLWFL 66
Query 64 RGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRTDP 123
RGDSN+GWL EHGVTIWDEWA GELGP+YGVQWRSWP P G HIDQIS L LRTDP
Sbjct 67 RGDSNVGWLREHGVTIWDEWADPQGELGPVYGVQWRSWPTPDGTHIDQISQVLQTLRTDP 126
Query 124 DSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASYAL 183
DSRR+IVSAWNV E++RMAL PCHAFFQFYVADG+LSCQLYQRSADLFLGVPFNIASYAL
Sbjct 127 DSRRMIVSAWNVAELDRMALAPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASYAL 186
Query 184 LTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEYTY 243
LTHM+A Q L GEFIWTGGDCHIYDNHVEQV QL REP P+P+L L S+F+Y +
Sbjct 187 LTHMVAQQTELEPGEFIWTGGDCHIYDNHVEQVTEQLGREPYPFPRLELRPAPSLFDYRF 246
Query 244 EDIVVKNYDPHPAIKAPVAV 263
ED+ V +Y HPAIKAPVAV
Sbjct 247 EDVTVTDYRHHPAIKAPVAV 266
>gi|271966278|ref|YP_003340474.1| Thymidylate synthase [Streptosporangium roseum DSM 43021]
gi|270509453|gb|ACZ87731.1| Thymidylate synthase [Streptosporangium roseum DSM 43021]
Length=265
Score = 432 bits (1110), Expect = 4e-119, Method: Compositional matrix adjust.
Identities = 201/262 (77%), Positives = 223/262 (86%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
T YEDLLR VL +GT K+DRTGTGTRS+FG Q+RYDLS GFPL+TTKKVH +S+ YELLW
Sbjct 4 TQYEDLLRLVLTSGTAKADRTGTGTRSVFGHQLRYDLSQGFPLVTTKKVHLRSIVYELLW 63
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSNIGWLH+HGVTIWDEWA GELGP+YG QWRSWPAP G HIDQ+S LD LR
Sbjct 64 FLRGDSNIGWLHKHGVTIWDEWADANGELGPVYGAQWRSWPAPDGRHIDQVSEVLDTLRR 123
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR+IVSAWNV E+++MAL PCHAFFQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 124 DPDSRRMIVSAWNVAELDKMALAPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 183
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+A QAGL G+FIWTGGDCHIYDNHVEQV QLSR P +P L L DS+F+Y
Sbjct 184 ALLTHMVAQQAGLKPGDFIWTGGDCHIYDNHVEQVTEQLSRTPFEFPGLRLRQADSLFDY 243
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
Y D+ V +Y HPAIKAPVAV
Sbjct 244 AYADVEVLDYRHHPAIKAPVAV 265
>gi|302532527|ref|ZP_07284869.1| thymidylate synthase [Streptomyces sp. C]
gi|302441422|gb|EFL13238.1| thymidylate synthase [Streptomyces sp. C]
Length=265
Score = 429 bits (1104), Expect = 1e-118, Method: Compositional matrix adjust.
Identities = 200/262 (77%), Positives = 221/262 (85%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
T YEDLLR VL +GT K+DRTGTGTRS+FG Q+RYDLS GFPL+TTKKVH KS+ YELLW
Sbjct 4 TQYEDLLRHVLTSGTAKADRTGTGTRSVFGHQLRYDLSQGFPLVTTKKVHLKSIVYELLW 63
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+GWL EHGVTIWDEWA GELGP+YGVQWRSWP P G H+DQI+ LD LR
Sbjct 64 FLRGDSNVGWLQEHGVTIWDEWADADGELGPVYGVQWRSWPTPDGRHVDQITEVLDTLRR 123
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR+IVSAWNV E+ RMAL PCHAFFQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 124 DPDSRRMIVSAWNVSELSRMALAPCHAFFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 183
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+A Q GL G+FIWTGGDCHIYDNHVEQV QLSR P +P+L L DS+F+Y
Sbjct 184 ALLTHMVAQQTGLEPGDFIWTGGDCHIYDNHVEQVTEQLSRTPYEFPRLNLRQADSLFDY 243
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
Y D+ V +Y HPAIKAPVAV
Sbjct 244 AYSDVEVLDYRHHPAIKAPVAV 265
>gi|269957617|ref|YP_003327406.1| thymidylate synthase [Xylanimonas cellulosilytica DSM 15894]
gi|269306298|gb|ACZ31848.1| thymidylate synthase [Xylanimonas cellulosilytica DSM 15894]
Length=272
Score = 428 bits (1101), Expect = 3e-118, Method: Compositional matrix adjust.
Identities = 201/262 (77%), Positives = 225/262 (86%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYE+LLR VL GT K DRTGTGT S+FG+Q+RYDLS GFPL+TTK+VH KSV YELLW
Sbjct 11 TPYENLLRDVLAHGTHKDDRTGTGTTSVFGRQLRYDLSQGFPLITTKRVHLKSVVYELLW 70
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRG+SN+ WL EHGV+IWDEWAS GELGP+YGVQWRSWP P G H+DQIS +D LRT
Sbjct 71 FLRGESNVRWLQEHGVSIWDEWASPAGELGPVYGVQWRSWPTPDGAHVDQISQVVDQLRT 130
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRR IVSAWNV EI+ MALPPCH FQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 131 NPDSRRHIVSAWNVAEIKNMALPPCHLLFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 190
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+AAQ GL VGEF+WTGGDCHIYDNH+ QV QLSR+P PY +L LA RDSIF+Y
Sbjct 191 ALLTHMVAAQTGLDVGEFVWTGGDCHIYDNHLAQVTEQLSRDPYPYARLELAPRDSIFDY 250
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
TY+D+VV +Y HPAIKA VAV
Sbjct 251 TYDDVVVHDYQHHPAIKAAVAV 272
>gi|256394947|ref|YP_003116511.1| thymidylate synthase [Catenulispora acidiphila DSM 44928]
gi|256361173|gb|ACU74670.1| thymidylate synthase [Catenulispora acidiphila DSM 44928]
Length=277
Score = 426 bits (1096), Expect = 1e-117, Method: Compositional matrix adjust.
Identities = 199/262 (76%), Positives = 223/262 (86%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
T YEDLL+ VL +GT K+DRTG GTRSLFG Q+RY L GFPL+TTKKVHFKSVAYELLW
Sbjct 16 TQYEDLLQRVLTSGTVKADRTGVGTRSLFGHQLRYRLQDGFPLITTKKVHFKSVAYELLW 75
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRG+ N+ WL EHGV+IWDEWA G+LGP+YGVQWRSWP P G H+DQI+ L LLRT
Sbjct 76 FLRGEGNVRWLQEHGVSIWDEWADAEGDLGPVYGVQWRSWPTPDGRHVDQIAEVLRLLRT 135
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRRI+VSAWNVGE+ MALPPCHAFFQFYVADG LSCQLYQRSAD+FLGVPFNIASY
Sbjct 136 DPDSRRIVVSAWNVGELTNMALPPCHAFFQFYVADGALSCQLYQRSADMFLGVPFNIASY 195
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+AAQ GL+VG+ +WTGGD HIYDNHVEQ RL L+RE R +P L L DS+F+Y
Sbjct 196 ALLTHMIAAQTGLAVGDLVWTGGDIHIYDNHVEQARLLLTREARLFPTLELKPADSLFDY 255
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
+YEDI V YDPHPAIKAPVAV
Sbjct 256 SYEDIAVLGYDPHPAIKAPVAV 277
>gi|302529833|ref|ZP_07282175.1| thymidylate synthase [Streptomyces sp. AA4]
gi|302438728|gb|EFL10544.1| thymidylate synthase [Streptomyces sp. AA4]
Length=265
Score = 425 bits (1092), Expect = 3e-117, Method: Compositional matrix adjust.
Identities = 198/262 (76%), Positives = 225/262 (86%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
T YEDLL+ VL+TG K DRTGTGTRS+FG Q+RY L+ GFPL+TTKKVHF+S+AYELLW
Sbjct 4 TQYEDLLQHVLDTGAEKGDRTGTGTRSIFGHQLRYRLADGFPLITTKKVHFRSIAYELLW 63
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL +HGVTIWDEWA+ G+LGP+YGVQWRSWP P G H+DQIS L LR
Sbjct 64 FLRGDSNVTWLRDHGVTIWDEWAAPDGDLGPVYGVQWRSWPTPDGGHVDQISDVLRTLRE 123
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRRIIVSAWNVG+I +MALPPCHAFFQFYVA+G LSCQLYQRSADLFLGVPFNIASY
Sbjct 124 NPDSRRIIVSAWNVGDIPQMALPPCHAFFQFYVANGELSCQLYQRSADLFLGVPFNIASY 183
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+A Q GL VG+FIWTGGDCHIYDNHVEQVR QLSR+ RP+P L L +S+F+Y
Sbjct 184 ALLTHMIADQVGLRVGDFIWTGGDCHIYDNHVEQVRKQLSRDARPFPTLSLKPAESLFDY 243
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
YED ++ YDPHP IKAPVAV
Sbjct 244 RYEDFSLEGYDPHPGIKAPVAV 265
>gi|260579743|ref|ZP_05847601.1| thymidylate synthase [Corynebacterium jeikeium ATCC 43734]
gi|258602129|gb|EEW15448.1| thymidylate synthase [Corynebacterium jeikeium ATCC 43734]
Length=273
Score = 425 bits (1092), Expect = 4e-117, Method: Compositional matrix adjust.
Identities = 195/262 (75%), Positives = 222/262 (85%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR +LETGTPK DRTGTGT SLFG+Q+RYDLSAGFPL+TTK VH KSV ELLW
Sbjct 12 TPYEDLLREILETGTPKGDRTGTGTTSLFGRQIRYDLSAGFPLITTKSVHVKSVVGELLW 71
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL E+G+ IW+EWA + G+LGP+YGVQWRSWP P+G+HIDQI+ AL+ LRT
Sbjct 72 FLRGDSNVRWLQENGIRIWNEWADENGDLGPVYGVQWRSWPTPNGQHIDQIAGALETLRT 131
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRR IVSAWNV E++ MALPPCH FQ YVADG+LSCQLYQRSAD+FLGVPFNIASY
Sbjct 132 NPDSRRNIVSAWNVSELDNMALPPCHLLFQLYVADGKLSCQLYQRSADMFLGVPFNIASY 191
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
+LLTHM A Q+GL VGEFIWTGGDCHIYDNHVEQV+LQLSR+ RPYP+L L +F Y
Sbjct 192 SLLTHMFAQQSGLEVGEFIWTGGDCHIYDNHVEQVQLQLSRDARPYPQLKLNKAADMFSY 251
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
+ DI YDPHP IKA VAV
Sbjct 252 DFSDIEFTGYDPHPVIKAKVAV 273
>gi|227487755|ref|ZP_03918071.1| thymidylate synthase [Corynebacterium glucuronolyticum ATCC 51867]
gi|227542399|ref|ZP_03972448.1| thymidylate synthase [Corynebacterium glucuronolyticum ATCC 51866]
gi|227092257|gb|EEI27569.1| thymidylate synthase [Corynebacterium glucuronolyticum ATCC 51867]
gi|227181597|gb|EEI62569.1| thymidylate synthase [Corynebacterium glucuronolyticum ATCC 51866]
Length=266
Score = 424 bits (1090), Expect = 7e-117, Method: Compositional matrix adjust.
Identities = 196/262 (75%), Positives = 223/262 (86%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR +LE G K DRTGTGT SLFG+QMR+ L+ FPL+TTKKVH+KSV ELLW
Sbjct 5 TPYEDLLREILEEGAHKDDRTGTGTTSLFGKQMRFHLAEAFPLITTKKVHWKSVVGELLW 64
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WLHE+GV+IWDEWA + GELGPIYGVQWRSWP P+G+HIDQI+ AL+LL+
Sbjct 65 FLRGDSNVAWLHENGVSIWDEWADENGELGPIYGVQWRSWPTPNGQHIDQIAGALELLKK 124
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR IVSAWNV E++ MALPPCH FQ YVADG+LSCQLYQRS D+FLGVPFNIASY
Sbjct 125 DPDSRRNIVSAWNVSELDNMALPPCHLLFQLYVADGKLSCQLYQRSCDMFLGVPFNIASY 184
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
+LLTHM A QAGL VG+F+WTGGDCHIYDNH EQVR QLSREPRPYP+L L S+F+Y
Sbjct 185 SLLTHMFAQQAGLDVGDFVWTGGDCHIYDNHREQVREQLSREPRPYPRLDLTRAPSMFDY 244
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
T+E I + YDPHP IKAPVAV
Sbjct 245 TFEHINLVGYDPHPTIKAPVAV 266
>gi|68535511|ref|YP_250216.1| thymidylate synthase [Corynebacterium jeikeium K411]
gi|123761908|sp|Q4JX59.1|TYSY_CORJK RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|68263110|emb|CAI36598.1| thyA [Corynebacterium jeikeium K411]
Length=273
Score = 423 bits (1088), Expect = 1e-116, Method: Compositional matrix adjust.
Identities = 194/262 (75%), Positives = 222/262 (85%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR +LETGTPK DRTGTGT SLFG+Q+RYDLSAGFPL+TTK VH KSV ELLW
Sbjct 12 TPYEDLLREILETGTPKGDRTGTGTTSLFGRQIRYDLSAGFPLITTKSVHVKSVVGELLW 71
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL E+G+ IW+EWA + G+LGP+YGVQWRSWP P+G+HIDQI+ AL+ L+T
Sbjct 72 FLRGDSNVRWLQENGIRIWNEWADENGDLGPVYGVQWRSWPTPNGQHIDQIAGALETLQT 131
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRR IVSAWNV E++ MALPPCH FQ YVA+G+LSCQLYQRSAD+FLGVPFNIASY
Sbjct 132 NPDSRRNIVSAWNVSELDNMALPPCHLLFQLYVANGKLSCQLYQRSADMFLGVPFNIASY 191
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
+LLTHM A QAGL VGEFIWTGGDCHIYDNHVEQV+LQLSR+ RPYP+L L +F Y
Sbjct 192 SLLTHMFAQQAGLEVGEFIWTGGDCHIYDNHVEQVKLQLSRDARPYPQLKLNKAADMFSY 251
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
+ DI YDPHP IKA VAV
Sbjct 252 DFSDIEFTGYDPHPVIKAKVAV 273
>gi|297153967|gb|ADI03679.1| thymidylate synthase [Streptomyces bingchenggensis BCW-1]
Length=265
Score = 422 bits (1086), Expect = 2e-116, Method: Compositional matrix adjust.
Identities = 195/262 (75%), Positives = 220/262 (84%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
T YEDLLR VL +GT K+DRTGTGTRS+FG Q+RYDL+ GFPL+TTKKVH +S+ YELLW
Sbjct 4 TQYEDLLRLVLTSGTAKADRTGTGTRSVFGHQLRYDLAQGFPLITTKKVHLRSIVYELLW 63
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+GWL EHG+TIWDEWA GELGP+YGVQWRSWPAP G HIDQIS LD LR
Sbjct 64 FLRGDSNVGWLREHGITIWDEWADANGELGPVYGVQWRSWPAPDGRHIDQISQVLDTLRR 123
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR+IVSAWNV E+ +MAL PCHA FQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 124 DPDSRRMIVSAWNVAELPKMALAPCHALFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 183
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+A QAGL G+F+WTGGDCHIYDNH++QV QLSR P +P L L DS+F Y
Sbjct 184 ALLTHMVAQQAGLEPGDFVWTGGDCHIYDNHIKQVTEQLSRTPFEFPGLRLRQADSLFAY 243
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
Y D+ + +Y HPAIKAPVAV
Sbjct 244 AYADVELLDYRHHPAIKAPVAV 265
>gi|302556750|ref|ZP_07309092.1| thymidylate synthase [Streptomyces griseoflavus Tu4000]
gi|302474368|gb|EFL37461.1| thymidylate synthase [Streptomyces griseoflavus Tu4000]
Length=265
Score = 421 bits (1081), Expect = 7e-116, Method: Compositional matrix adjust.
Identities = 196/262 (75%), Positives = 217/262 (83%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
T YEDLL+ VL +GT K+DRTGTGTRS+FG Q+RYDLS GFPL+TTKKVH KS+ YELLW
Sbjct 4 TQYEDLLQLVLTSGTAKADRTGTGTRSVFGHQLRYDLSQGFPLVTTKKVHLKSIVYELLW 63
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSN+ WL EHGVTIWDEWA D G+LGP+YG QWRSWP P G HIDQI L LR
Sbjct 64 FLRGDSNVRWLQEHGVTIWDEWADDNGDLGPVYGAQWRSWPTPDGRHIDQIEEVLGTLRR 123
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR+IVSAWNV E+ +MAL PCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY
Sbjct 124 DPDSRRMIVSAWNVSELSKMALAPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 183
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHM+A Q+GL G+FIWTGGDCHIYDNHV QV QLSR P +P L L DS+F+Y
Sbjct 184 ALLTHMVAQQSGLEPGDFIWTGGDCHIYDNHVAQVTEQLSRTPFAFPALELRRADSLFDY 243
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
+Y D+ V Y HPAIKAPVAV
Sbjct 244 SYSDVQVAGYRHHPAIKAPVAV 265
>gi|317508366|ref|ZP_07966039.1| thymidylate synthase [Segniliparus rugosus ATCC BAA-974]
gi|316253323|gb|EFV12720.1| thymidylate synthase [Segniliparus rugosus ATCC BAA-974]
Length=270
Score = 419 bits (1076), Expect = 3e-115, Method: Compositional matrix adjust.
Identities = 193/262 (74%), Positives = 221/262 (85%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VLE G +SDRTGTGT S+FG Q+RYDL+ GFPL+TTKKVH KS+ YELLW
Sbjct 9 TPYEDLLRLVLEQGVERSDRTGTGTLSVFGHQLRYDLAKGFPLITTKKVHLKSIVYELLW 68
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGD+N+ WL E GVTIWDEWA + G LGP+YG QWRSWPAP G +DQI+ AL LLRT
Sbjct 69 FLRGDTNVRWLQERGVTIWDEWAREDGGLGPVYGAQWRSWPAPDGAVVDQIAQALHLLRT 128
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DP SRRI+VSAWNVGE+ +MAL PCH FQFYVADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 129 DPHSRRILVSAWNVGELPKMALAPCHILFQFYVADGKLSCQLYQRSADLFLGVPFNIASY 188
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTHMMA QAGL G+F+WTGGDCH+Y NHV+Q R QL+R+P PYP+L LA+R S+FE+
Sbjct 189 ALLTHMMAQQAGLEAGDFVWTGGDCHLYLNHVDQAREQLARDPFPYPRLELAERPSVFEH 248
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
YED+ + Y HPAIKAPVAV
Sbjct 249 EYEDVRILGYQSHPAIKAPVAV 270
>gi|340793614|ref|YP_004759077.1| Thymidylate synthase [Corynebacterium variabile DSM 44702]
gi|340533524|gb|AEK36004.1| Thymidylate synthase [Corynebacterium variabile DSM 44702]
Length=285
Score = 418 bits (1075), Expect = 4e-115, Method: Compositional matrix adjust.
Identities = 194/262 (75%), Positives = 217/262 (83%), Gaps = 0/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLL +LE G K DRTGTGTRSLF +QMR+DL+ GFPL+TTKKVH S+ ELLW
Sbjct 24 TPYEDLLAEILEHGVHKDDRTGTGTRSLFARQMRFDLAEGFPLITTKKVHLHSIVGELLW 83
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGDSNI WLHE+ V+IWDEWA + GELGP+YGVQWRSWP P G HIDQI+AAL+ L+
Sbjct 84 FLRGDSNIAWLHENKVSIWDEWADEDGELGPVYGVQWRSWPTPDGRHIDQITAALETLKN 143
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
+PDSRR IVSAWNV E+E MALPPCH FQ YVADG+LSCQLYQRSAD+FLGVPFNIASY
Sbjct 144 NPDSRRNIVSAWNVSELENMALPPCHLLFQLYVADGKLSCQLYQRSADMFLGVPFNIASY 203
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
A+LTHM A QAGL VGEF+WTGGDCHIYDNHV+QV LQLSRE RPYP L L +F Y
Sbjct 204 AILTHMFAQQAGLEVGEFVWTGGDCHIYDNHVDQVALQLSREARPYPTLNLHKAADLFSY 263
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
++DI V YDPHP IKAPVAV
Sbjct 264 RFDDIEVIGYDPHPGIKAPVAV 285
>gi|333921298|ref|YP_004494879.1| Thymidylate synthase [Amycolicicoccus subflavus DQS3-9A1]
gi|333483519|gb|AEF42079.1| Thymidylate synthase [Amycolicicoccus subflavus DQS3-9A1]
Length=272
Score = 416 bits (1069), Expect = 2e-114, Method: Compositional matrix adjust.
Identities = 196/263 (75%), Positives = 221/263 (85%), Gaps = 1/263 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
TPYEDLLR VLE+G PK DRTGTGTRS+FG+Q+RYDL+ GFPL+TTK+VH KSV YELLW
Sbjct 10 TPYEDLLRDVLESGEPKPDRTGTGTRSVFGRQLRYDLTQGFPLITTKRVHLKSVVYELLW 69
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRG+SN+ WL EHGVTIWDEWA + GELGP+YGVQWRSWP P G HIDQIS ++ +R
Sbjct 70 FLRGESNVRWLQEHGVTIWDEWAREDGELGPVYGVQWRSWPTPDGRHIDQISQVVESIRD 129
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
P SRR +VSAWNVGEIE MALPPCHAFFQFYVA G+LSCQLYQRSADLFLGVPFNIASY
Sbjct 130 APHSRRHLVSAWNVGEIENMALPPCHAFFQFYVAGGKLSCQLYQRSADLFLGVPFNIASY 189
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADR-DSIFE 240
ALLT M+A Q G GEFIWTGGDCHIYDNHVEQV QL R+P PYP L A + ++F+
Sbjct 190 ALLTEMVAQQTGYQPGEFIWTGGDCHIYDNHVEQVTRQLERDPYPYPALKFARKPTTLFD 249
Query 241 YTYEDIVVKNYDPHPAIKAPVAV 263
Y Y+DI+V+NY HP IKAPVAV
Sbjct 250 YDYDDIIVENYRHHPPIKAPVAV 272
>gi|336324919|ref|YP_004604885.1| Thymidylate synthase [Corynebacterium resistens DSM 45100]
gi|336100901|gb|AEI08721.1| Thymidylate synthase [Corynebacterium resistens DSM 45100]
Length=278
Score = 416 bits (1069), Expect = 2e-114, Method: Compositional matrix adjust.
Identities = 190/263 (73%), Positives = 215/263 (82%), Gaps = 0/263 (0%)
Query 1 VTPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELL 60
TPYEDLLR +LETG PK DRTGTGT SLFG+Q+RYDL GFPL+TTKKVH KSV ELL
Sbjct 16 ATPYEDLLREILETGAPKGDRTGTGTSSLFGRQIRYDLQQGFPLITTKKVHVKSVVGELL 75
Query 61 WFLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLR 120
WFL+GDSN+ WL E+G+ IW+EWA + G+LGP+YGVQWRSWP P G H+DQI+AAL+ L+
Sbjct 76 WFLKGDSNVRWLQENGIRIWNEWADENGDLGPVYGVQWRSWPTPDGRHVDQIAAALETLK 135
Query 121 TDPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIAS 180
+PDSRR IVSAWNV E+E MALPPCH FQ YVADG+LSCQLYQRSAD+FLGVPFNIAS
Sbjct 136 ANPDSRRNIVSAWNVSELENMALPPCHLLFQLYVADGKLSCQLYQRSADMFLGVPFNIAS 195
Query 181 YALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFE 240
Y+LLTHM A QAGL VGEFIWTGGDCHIYDNH EQV QL+R+PRPYP L L +F
Sbjct 196 YSLLTHMFAQQAGLDVGEFIWTGGDCHIYDNHREQVETQLTRDPRPYPTLELNKAADMFS 255
Query 241 YTYEDIVVKNYDPHPAIKAPVAV 263
Y + DI YDPHP IKA VAV
Sbjct 256 YDFSDIHFAGYDPHPTIKAQVAV 278
>gi|152968378|ref|YP_001364162.1| Thymidylate synthase [Kineococcus radiotolerans SRS30216]
gi|189036937|sp|A6WGF9.1|TYSY_KINRD RecName: Full=Thymidylate synthase; Short=TS; Short=TSase
gi|151362895|gb|ABS05898.1| Thymidylate synthase [Kineococcus radiotolerans SRS30216]
Length=268
Score = 416 bits (1068), Expect = 2e-114, Method: Compositional matrix adjust.
Identities = 193/262 (74%), Positives = 223/262 (86%), Gaps = 1/262 (0%)
Query 2 TPYEDLLRFVLETGTPKSDRTGTGTRSLFGQQMRYDLSAGFPLLTTKKVHFKSVAYELLW 61
T YEDLLR VL TGTPKSDRTGTGTRS+FG Q+RYDLSAGFPL+TTK+VHFKS+A ELLW
Sbjct 8 TQYEDLLRHVLATGTPKSDRTGTGTRSVFGHQLRYDLSAGFPLVTTKRVHFKSIALELLW 67
Query 62 FLRGDSNIGWLHEHGVTIWDEWASDTGELGPIYGVQWRSWPAPSGEHIDQISAALDLLRT 121
FLRGD N+ WL E GVTIWDEWA + G+LGP+YGVQWRSWP P G H+DQI+ L LRT
Sbjct 68 FLRGDGNVRWLQERGVTIWDEWADENGDLGPVYGVQWRSWPTPDGRHVDQIAQVLHTLRT 127
Query 122 DPDSRRIIVSAWNVGEIERMALPPCHAFFQFYVADGRLSCQLYQRSADLFLGVPFNIASY 181
DPDSRR++VSAWNV E++RMAL PCHAFFQF+VADG+LSCQLYQRSADLFLGVPFNIASY
Sbjct 128 DPDSRRMVVSAWNVAELDRMALAPCHAFFQFHVADGKLSCQLYQRSADLFLGVPFNIASY 187
Query 182 ALLTHMMAAQAGLSVGEFIWTGGDCHIYDNHVEQVRLQLSREPRPYPKLLLADRDSIFEY 241
ALLTH++AA+ GL VG+F+WTGGD H+YDNHVEQV QL+R P P+P+L + +FE+
Sbjct 188 ALLTHLVAAEVGLEVGDFVWTGGDVHVYDNHVEQVTEQLTRTPYPFPRLAVRPA-GLFEH 246
Query 242 TYEDIVVKNYDPHPAIKAPVAV 263
YED V +Y HPAIKAPVAV
Sbjct 247 EYEDFEVLDYRHHPAIKAPVAV 268
Lambda K H
0.322 0.139 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Effective search space used: 394810015572
Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
Posted date: Sep 5, 2011 4:36 AM
Number of letters in database: 5,219,829,388
Number of sequences in database: 15,229,318
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40