BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2768c

Length=394
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|57117022|ref|YP_177906.1|  PPE family protein [Mycobacterium t...   751    0.0   
gi|254232866|ref|ZP_04926193.1|  PPE family protein [Mycobacteriu...   751    0.0   
gi|340627770|ref|YP_004746222.1|  PPE family protein [Mycobacteri...   748    0.0   
gi|289553446|ref|ZP_06442656.1|  PPE family protein [Mycobacteriu...   748    0.0   
gi|31793943|ref|NP_856436.1|  PPE family protein [Mycobacterium b...   748    0.0   
gi|148823956|ref|YP_001288710.1|  PPE family protein [Mycobacteri...   748    0.0   
gi|15842306|ref|NP_337343.1|  PPE family protein [Mycobacterium t...   747    0.0   
gi|344220596|gb|AEN01227.1|  PPE family protein [Mycobacterium tu...   746    0.0   
gi|167968597|ref|ZP_02550874.1|  PPE family protein [Mycobacteriu...   720    0.0   
gi|254551827|ref|ZP_05142274.1|  PPE family protein [Mycobacteriu...   716    0.0   
gi|183981963|ref|YP_001850254.1|  PPE family protein, PPE15_1 [My...   432    3e-119
gi|240173194|ref|ZP_04751852.1|  PPE family protein, PPE15_1 [Myc...   403    3e-110
gi|118619703|ref|YP_908035.1|  PPE family protein [Mycobacterium ...   393    3e-107
gi|183984423|ref|YP_001852714.1|  PPE family protein, PPE15 [Myco...   392    4e-107
gi|289753101|ref|ZP_06512479.1|  PPE family protein [Mycobacteriu...   349    4e-94 
gi|253799929|ref|YP_003032930.1|  PPE family protein [Mycobacteri...   348    1e-93 
gi|15840468|ref|NP_335505.1|  PPE family protein [Mycobacterium t...   347    1e-93 
gi|339631101|ref|YP_004722743.1|  PPE family protein [Mycobacteri...   346    4e-93 
gi|121636969|ref|YP_977192.1|  PPE family protein [Mycobacterium ...   345    6e-93 
gi|344218866|gb|AEM99496.1|  PPE family protein [Mycobacterium tu...   345    6e-93 
gi|340626050|ref|YP_004744502.1|  PPE family protein [Mycobacteri...   345    9e-93 
gi|340627772|ref|YP_004746224.1|  PPE family protein [Mycobacteri...   323    5e-86 
gi|297730553|ref|ZP_06959671.1|  PPE family protein [Mycobacteriu...   319    6e-85 
gi|31793945|ref|NP_856438.1|  PPE family protein [Mycobacterium b...   318    9e-85 
gi|254550024|ref|ZP_05140471.1|  PPE family protein [Mycobacteriu...   318    1e-84 
gi|289746573|ref|ZP_06505951.1|  PPE family protein [Mycobacteriu...   318    1e-84 
gi|13377911|gb|AAK20895.1|  Rv2770c-like protein [Mycobacterium m...   317    2e-84 
gi|57117024|ref|YP_177677.1|  PPE family protein [Mycobacterium t...   317    2e-84 
gi|15842308|ref|NP_337345.1|  PPE family protein [Mycobacterium t...   316    4e-84 
gi|289444315|ref|ZP_06434059.1|  PPE family protein [Mycobacteriu...   315    9e-84 
gi|308374682|ref|ZP_07436980.2|  LOW QUALITY PROTEIN: PPE family ...   307    2e-81 
gi|183981960|ref|YP_001850251.1|  PPE family protein, PPE44 [Myco...   305    1e-80 
gi|294994137|ref|ZP_06799828.1|  PPE family protein [Mycobacteriu...   290    2e-76 
gi|289448425|ref|ZP_06438169.1|  PPE family protein [Mycobacteriu...   290    3e-76 
gi|167968599|ref|ZP_02550876.1|  PPE family protein [Mycobacteriu...   289    7e-76 
gi|306777051|ref|ZP_07415388.1|  PPE family protein [Mycobacteriu...   288    1e-75 
gi|118617719|ref|YP_906051.1|  PPE family protein [Mycobacterium ...   287    2e-75 
gi|118464457|ref|YP_880591.1|  PPE family protein [Mycobacterium ...   261    1e-67 
gi|212595937|gb|ACJ35536.1|  PPE10 [Mycobacterium avium subsp. av...   260    3e-67 
gi|41408673|ref|NP_961509.1|  hypothetical protein MAP2575c [Myco...   259    5e-67 
gi|240173300|ref|ZP_04751958.1|  PPE family protein [Mycobacteriu...   250    3e-64 
gi|254774062|ref|ZP_05215578.1|  hypothetical protein MaviaA2_052...   248    1e-63 
gi|336461476|gb|EGO40346.1|  PPE-repeat containing protein [Mycob...   248    2e-63 
gi|41407101|ref|NP_959937.1|  hypothetical protein MAP1003c [Myco...   246    3e-63 
gi|240170332|ref|ZP_04748991.1|  PPE family protein, PPE15 [Mycob...   243    4e-62 
gi|183982688|ref|YP_001850979.1|  PPE family protein, PPE31_1 [My...   241    1e-61 
gi|118618459|ref|YP_906791.1|  PPE family protein [Mycobacterium ...   222    7e-56 
gi|342862087|ref|ZP_08718730.1|  hypothetical protein MCOL_24471 ...   220    3e-55 
gi|342861296|ref|ZP_08717944.1|  PPE family protein [Mycobacteriu...   220    4e-55 
gi|240172861|ref|ZP_04751520.1|  PPE family protein, PPE31 [Mycob...   216    7e-54 


>gi|57117022|ref|YP_177906.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148662610|ref|YP_001284133.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|254365419|ref|ZP_04981464.1| PPE family protein [Mycobacterium tuberculosis str. Haarlem]
 23 more sequence titles
 Length=394

 Score =  751 bits (1940),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 394/394 (100%), Positives = 394/394 (100%), Gaps = 0/394 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
            GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI
Sbjct  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
            TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV
Sbjct  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM
Sbjct  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV
Sbjct  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394


>gi|254232866|ref|ZP_04926193.1| PPE family protein [Mycobacterium tuberculosis C]
 gi|289754874|ref|ZP_06514252.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|124601925|gb|EAY60935.1| PPE family protein [Mycobacterium tuberculosis C]
 gi|289695461|gb|EFD62890.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|323718615|gb|EGB27779.1| PPE family protein [Mycobacterium tuberculosis CDC1551A]
Length=462

 Score =  751 bits (1939),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 394/394 (100%), Positives = 394/394 (100%), Gaps = 0/394 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP
Sbjct  69   MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  128

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL
Sbjct  129  ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  188

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA
Sbjct  189  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  248

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
            GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI
Sbjct  249  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  308

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
            TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV
Sbjct  309  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  368

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM
Sbjct  369  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  428

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV
Sbjct  429  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  462


>gi|340627770|ref|YP_004746222.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340005960|emb|CCC45127.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=394

 Score =  748 bits (1932),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/394 (99%), Positives = 393/394 (99%), Gaps = 0/394 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASMSMVVAAQPYLAWLTYTAESAA AAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAARAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
            GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI
Sbjct  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
            TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV
Sbjct  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM
Sbjct  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV
Sbjct  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394


>gi|289553446|ref|ZP_06442656.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|289438078|gb|EFD20571.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
Length=411

 Score =  748 bits (1932),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/394 (99%), Positives = 393/394 (99%), Gaps = 0/394 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP
Sbjct  18   MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  77

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL
Sbjct  78   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  137

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA
Sbjct  138  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  197

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
            GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI
Sbjct  198  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  257

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
            TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV
Sbjct  258  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  317

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGS WAVPEEAGPVAAM
Sbjct  318  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSVWAVPEEAGPVAAM  377

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV
Sbjct  378  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  411


>gi|31793943|ref|NP_856436.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|121638647|ref|YP_978871.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224991139|ref|YP_002645828.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 8 more sequence titles
 Length=394

 Score =  748 bits (1931),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/394 (99%), Positives = 393/394 (99%), Gaps = 0/394 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
            GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI
Sbjct  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
            TFVQNAINGAVNTTAWFVMATI NAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV
Sbjct  241  TFVQNAINGAVNTTAWFVMATIRNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM
Sbjct  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV
Sbjct  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394


>gi|148823956|ref|YP_001288710.1| PPE family protein [Mycobacterium tuberculosis F11]
 gi|253798149|ref|YP_003031150.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289762940|ref|ZP_06522318.1| PPE family protein [Mycobacterium tuberculosis GM 1503]
 gi|148722483|gb|ABR07108.1| PPE family protein [Mycobacterium tuberculosis F11]
 gi|253319652|gb|ACT24255.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289710446|gb|EFD74462.1| PPE family protein [Mycobacterium tuberculosis GM 1503]
 gi|328457922|gb|AEB03345.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
Length=394

 Score =  748 bits (1930),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 393/394 (99%), Positives = 393/394 (99%), Gaps = 0/394 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
            GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI
Sbjct  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
            TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV
Sbjct  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGS WAVPEEAGPVAAM
Sbjct  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSVWAVPEEAGPVAAM  360

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV
Sbjct  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394


>gi|15842306|ref|NP_337343.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|13882601|gb|AAK47157.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
Length=462

 Score =  747 bits (1929),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 392/394 (99%), Positives = 392/394 (99%), Gaps = 0/394 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP
Sbjct  69   MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  128

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL
Sbjct  129  ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  188

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA
Sbjct  189  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  248

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
            GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI
Sbjct  249  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  308

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
            TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV
Sbjct  309  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  368

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM
Sbjct  369  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  428

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            PGMAGISGAAK  GAYAGPRYGFKPIVMPKQVVV
Sbjct  429  PGMAGISGAAKXXGAYAGPRYGFKPIVMPKQVVV  462


>gi|344220596|gb|AEN01227.1| PPE family protein [Mycobacterium tuberculosis CTRI-2]
Length=394

 Score =  746 bits (1925),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 392/394 (99%), Positives = 392/394 (99%), Gaps = 0/394 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAA EAAFAMTVPPAEVAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAALEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
            GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI
Sbjct  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
            TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV
Sbjct  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGS WAVPEEAGPVAAM
Sbjct  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSVWAVPEEAGPVAAM  360

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV
Sbjct  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394


>gi|167968597|ref|ZP_02550874.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|294994139|ref|ZP_06799830.1| PPE family protein [Mycobacterium tuberculosis 210]
 gi|306777049|ref|ZP_07415386.1| PPE family protein [Mycobacterium tuberculosis SUMu001]
 19 more sequence titles
 Length=380

 Score =  720 bits (1859),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 380/380 (100%), Positives = 380/380 (100%), Gaps = 0/380 (0%)

Query  15   MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  74
            MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA
Sbjct  1    MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  60

Query  75   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  134
            WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM
Sbjct  61   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  120

Query  135  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  194
            ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST
Sbjct  121  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  180

Query  195  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT  254
            VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT
Sbjct  181  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT  240

Query  255  AWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLTASL  314
            AWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLTASL
Sbjct  241  AWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLTASL  300

Query  315  GEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAMPGMAGISGAAKGAG  374
            GEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAMPGMAGISGAAKGAG
Sbjct  301  GEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAMPGMAGISGAAKGAG  360

Query  375  AYAGPRYGFKPIVMPKQVVV  394
            AYAGPRYGFKPIVMPKQVVV
Sbjct  361  AYAGPRYGFKPIVMPKQVVV  380


>gi|254551827|ref|ZP_05142274.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|297635377|ref|ZP_06953157.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
 gi|297732375|ref|ZP_06961493.1| PPE family protein [Mycobacterium tuberculosis KZN R506]
 gi|313659707|ref|ZP_07816587.1| PPE family protein [Mycobacterium tuberculosis KZN V2475]
Length=380

 Score =  716 bits (1849),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 379/380 (99%), Positives = 379/380 (99%), Gaps = 0/380 (0%)

Query  15   MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  74
            MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA
Sbjct  1    MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  60

Query  75   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  134
            WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM
Sbjct  61   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  120

Query  135  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  194
            ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST
Sbjct  121  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  180

Query  195  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT  254
            VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT
Sbjct  181  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT  240

Query  255  AWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLTASL  314
            AWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLTASL
Sbjct  241  AWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLTASL  300

Query  315  GEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAMPGMAGISGAAKGAG  374
            GEASSVGGLSVPAGWSTAAPAMTSGTTALEGS WAVPEEAGPVAAMPGMAGISGAAKGAG
Sbjct  301  GEASSVGGLSVPAGWSTAAPAMTSGTTALEGSVWAVPEEAGPVAAMPGMAGISGAAKGAG  360

Query  375  AYAGPRYGFKPIVMPKQVVV  394
            AYAGPRYGFKPIVMPKQVVV
Sbjct  361  AYAGPRYGFKPIVMPKQVVV  380


>gi|183981963|ref|YP_001850254.1| PPE family protein, PPE15_1 [Mycobacterium marinum M]
 gi|183175289|gb|ACC40399.1| PPE family protein, PPE15_1 [Mycobacterium marinum M]
Length=393

 Score =  432 bits (1112),  Expect = 3e-119, Method: Compositional matrix adjust.
 Identities = 294/394 (75%), Positives = 324/394 (83%), Gaps = 1/394 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINSTRMYAGAGA P+MAA A WN LAVEL TTA+S ESV+ QLTTEQW+GP
Sbjct  1    MDFGALPPEINSTRMYAGAGATPMMAAAAAWNRLAVELGTTAASFESVVTQLTTEQWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS SM VA QPYLAWLTYTAESAAHA AQA ASAAAFEAAFA TVPPA VAANRA LA L
Sbjct  61   ASTSMAVAVQPYLAWLTYTAESAAHAGAQATASAAAFEAAFAATVPPAAVAANRAQLAML  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            V+TN+LGQNTPAI ATEA YGEMWAQDALAMYGYAASSAAAG LNPL TP+Q AN AGLA
Sbjct  121  VSTNILGQNTPAIAATEAQYGEMWAQDALAMYGYAASSAAAGTLNPLTTPAQIANPAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAVS AAAA+TV+QVGLG+LI+N+P AVMG ASP  S  DA GL  ++QDI  +LG 
Sbjct  181  SQAAAVSQAAAATTVEQVGLGNLITNVPGAVMGLASPAASLVDATGLSTLVQDISSVLGT  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
             F+QNAINGAVNT AWFVMA IPN+VFLGH   A+  A    AAD  PA A AAGL H V
Sbjct  241  PFLQNAINGAVNTAAWFVMAAIPNSVFLGHTLNAIETAGAPVAADLAPALAPAAGLRHAV  300

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
             P+  GGA + A LG+A+ VG LSVP GWS+AAPA+TSGTTAL+GSGWAVPEE+GP+AAM
Sbjct  301  APLSFGGAGVEAGLGQAAGVGKLSVPVGWSSAAPALTSGTTALDGSGWAVPEESGPIAAM  360

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            PG  G++ A KG G +AGPRYGFKP VMPKQVVV
Sbjct  361  PGGPGMAVAGKG-GGFAGPRYGFKPTVMPKQVVV  393


>gi|240173194|ref|ZP_04751852.1| PPE family protein, PPE15_1 [Mycobacterium kansasii ATCC 12478]
Length=384

 Score =  403 bits (1035),  Expect = 3e-110, Method: Compositional matrix adjust.
 Identities = 297/394 (76%), Positives = 319/394 (81%), Gaps = 10/394 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINS RMYAGAGAAP+MAA A W+ LAVELSTTA+SVESVI QLTTEQWLGP
Sbjct  1    MDFGALPPEINSARMYAGAGAAPMMAAAAAWHRLAVELSTTAASVESVITQLTTEQWLGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASMSM  AAQPYLAWLTYTAESAAHA +QA ASAAAFEAAFA TVPPAEVAANRALLAAL
Sbjct  61   ASMSMAAAAQPYLAWLTYTAESAAHAGSQATASAAAFEAAFAATVPPAEVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATN+LGQNTPAI ATEAHYGEMWAQDALAMYGYAASSAAAG LNPL TPS+ AN AGLA
Sbjct  121  VATNILGQNTPAIAATEAHYGEMWAQDALAMYGYAASSAAAGTLNPLTTPSRIANPAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAV  AAA  T QQVGL +LI+N+PN VMG ASP  S  DA  LGGII D   LLG 
Sbjct  181  AQAAAVGQAAATGTAQQVGLANLITNVPNTVMGLASPAASVFDATALGGIIDD---LLGN  237

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
            TFVQNAINGAVNT AWFVMATIPNAVFLGHA          +AA  VP  A AA   +  
Sbjct  238  TFVQNAINGAVNTAAWFVMATIPNAVFLGHALDVEG----LSAAQLVPTIAGAAATTNAA  293

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
                 G  S+ A +G+AS+VG L+VPA WS+AAPA+ SGTTALEGSGWAVPEEAGPV AM
Sbjct  294  A--PAGAGSVLAGMGQASAVGKLAVPASWSSAAPALPSGTTALEGSGWAVPEEAGPVTAM  351

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            PG  G++ A+KG G YAGPRYGF+P VMPKQVVV
Sbjct  352  PGGPGMAAASKG-GGYAGPRYGFRPTVMPKQVVV  384


>gi|118619703|ref|YP_908035.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118571813|gb|ABL06564.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=390

 Score =  393 bits (1009),  Expect = 3e-107, Method: Compositional matrix adjust.
 Identities = 274/396 (70%), Positives = 307/396 (78%), Gaps = 8/396 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINS RMYAGAGA P+MAA A WNGLAVEL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAASAAWNGLAVELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASM+M+ AAQPYLAWLTYT+E+A HA AQA ASAAA+EAAFAMTVPP  VAANR+LLAAL
Sbjct  61   ASMAMIAAAQPYLAWLTYTSEAAMHAGAQAAASAAAYEAAFAMTVPPPVVAANRSLLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATN LG NTPAIMATEA Y EMWAQDA AMYGYAA+S+ +G L PL TP QT N  GLA
Sbjct  121  VATNFLGINTPAIMATEALYAEMWAQDAGAMYGYAAASSTSGSLQPLSTPQQTTNPGGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q+AAVS AAA++     G  SL+SNLPN +MG ASP+TSA DA GLGGIIQDIE+ LGI
Sbjct  181  AQSAAVSQAAASAAATD-GTTSLLSNLPNTIMGLASPITSAIDATGLGGIIQDIEDFLGI  239

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNP--ATVTAAADAVPAAAAAAGLAH  298
             FV N INGAVNT AW+  ATIP A+FL +A     P  A   A   A  AAAA AGLA+
Sbjct  240  PFVANVINGAVNTAAWYTTATIPTAIFLANALNTGAPVIAAEGAIEAAEGAAAATAGLAN  299

Query  299  TVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVA  358
            TVTP GVG     A+LGEA+ VG L+VP  WS A P   + T AL GSGW VPEEA PV+
Sbjct  300  TVTPTGVG-----AALGEATLVGKLAVPTSWSNALPKTAATTGALGGSGWTVPEEAAPVS  354

Query  359  AMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
             + G+ G++ AAKGAGAYAGPRYGFKPIVMPKQVVV
Sbjct  355  GVAGVPGMAAAAKGAGAYAGPRYGFKPIVMPKQVVV  390


>gi|183984423|ref|YP_001852714.1| PPE family protein, PPE15 [Mycobacterium marinum M]
 gi|183177749|gb|ACC42859.1| PPE family protein, PPE15 [Mycobacterium marinum M]
Length=390

 Score =  392 bits (1008),  Expect = 4e-107, Method: Compositional matrix adjust.
 Identities = 272/396 (69%), Positives = 307/396 (78%), Gaps = 8/396 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINS RMYAGAGA P+MAA A WNGLAVEL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAASAAWNGLAVELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASM+M+ AAQPYLAWLTYT+E+A HA AQA ASAAA+EAAFAMTVPP  VAANR+LLAAL
Sbjct  61   ASMAMIAAAQPYLAWLTYTSEAAMHAGAQAAASAAAYEAAFAMTVPPPVVAANRSLLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATN LG NTPAIMATEA Y EMWAQDA AMYGYAA+S+ +G L PL TP QT N  GLA
Sbjct  121  VATNFLGINTPAIMATEALYAEMWAQDAGAMYGYAAASSTSGSLQPLSTPQQTTNPGGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q+AAVS AAA++     G+ SL+SNLPN +MG ASP+TSA DA GLGGIIQDIE+ LGI
Sbjct  181  AQSAAVSQAAASAAATD-GITSLLSNLPNTIMGLASPITSAIDATGLGGIIQDIEDFLGI  239

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPAT--VTAAADAVPAAAAAAGLAH  298
             FV N ING VNT AW+  ATIP A+FL +A     P      A   A  AAAA AGLA+
Sbjct  240  GFVANVINGGVNTAAWYTTATIPTAIFLANALDTGAPVVAAEGAIEAAEGAAAATAGLAN  299

Query  299  TVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVA  358
            TVTP GVG     A+LGEA+ VG L+VP  WS+A P   + T AL GSGW VPEEA PV+
Sbjct  300  TVTPTGVG-----AALGEATLVGKLAVPTSWSSALPETAATTGALGGSGWTVPEEAAPVS  354

Query  359  AMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
             + G+ G++ AAKGAGAYAGPRYGFKPIVMPKQVVV
Sbjct  355  GVAGVPGMAAAAKGAGAYAGPRYGFKPIVMPKQVVV  390


>gi|289753101|ref|ZP_06512479.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|289693688|gb|EFD61117.1| PPE family protein [Mycobacterium tuberculosis EAS054]
Length=391

 Score =  349 bits (896),  Expect = 4e-94, Method: Compositional matrix adjust.
 Identities = 280/398 (71%), Positives = 308/398 (78%), Gaps = 11/398 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  SQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAF---AALNPATVTAAADAVPAAAAAAGLA  297
             FV N IN AVNT AW+V A IP A+FL +A    A +  A     A    A+AAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  356
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355

Query  357  VAAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            V  M  M G++ AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  356  VTGM--MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|253799929|ref|YP_003032930.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289555178|ref|ZP_06444388.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|297633568|ref|ZP_06951348.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
 gi|253321432|gb|ACT26035.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|289439810|gb|EFD22303.1| PPE family protein [Mycobacterium tuberculosis KZN 605]
 gi|328459673|gb|AEB05096.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
Length=391

 Score =  348 bits (892),  Expect = 1e-93, Method: Compositional matrix adjust.
 Identities = 280/398 (71%), Positives = 308/398 (78%), Gaps = 11/398 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMAMVTAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAF---AALNPATVTAAADAVPAAAAAAGLA  297
             FV N IN AVNT AW+V A IP A+FL +A    A +  A     A    A+AAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  356
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355

Query  357  VAAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            V  M  M G++ AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  356  VTGM--MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|15840468|ref|NP_335505.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|31792231|ref|NP_854724.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|57116813|ref|YP_177778.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 50 more sequence titles
 Length=391

 Score =  347 bits (891),  Expect = 1e-93, Method: Compositional matrix adjust.
 Identities = 280/398 (71%), Positives = 308/398 (78%), Gaps = 11/398 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAF---AALNPATVTAAADAVPAAAAAAGLA  297
             FV N IN AVNT AW+V A IP A+FL +A    A +  A     A    A+AAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  356
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355

Query  357  VAAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            V  M  M G++ AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  356  VTGM--MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|339631101|ref|YP_004722743.1| PPE family protein [Mycobacterium africanum GM041182]
 gi|339330457|emb|CCC26122.1| PPE family protein [Mycobacterium africanum GM041182]
Length=391

 Score =  346 bits (888),  Expect = 4e-93, Method: Compositional matrix adjust.
 Identities = 279/398 (71%), Positives = 307/398 (78%), Gaps = 11/398 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFG LPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGTLPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAF---AALNPATVTAAADAVPAAAAAAGLA  297
             FV N IN AVNT AW+V A IP A+FL +A    A +  A     A    A+AAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  356
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355

Query  357  VAAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            V  M  M G++ AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  356  VTGM--MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|121636969|ref|YP_977192.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224989441|ref|YP_002644128.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|121492616|emb|CAL71084.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224772554|dbj|BAH25360.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 gi|341600985|emb|CCC63656.1| PPE family protein [Mycobacterium bovis BCG str. Moreau RDJ]
Length=391

 Score =  345 bits (886),  Expect = 6e-93, Method: Compositional matrix adjust.
 Identities = 279/398 (71%), Positives = 307/398 (78%), Gaps = 11/398 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT    GLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTKPGGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAF---AALNPATVTAAADAVPAAAAAAGLA  297
             FV N IN AVNT AW+V A IP A+FL +A    A +  A     A    A+AAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  356
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355

Query  357  VAAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            V  M  M G++ AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  356  VTGM--MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|344218866|gb|AEM99496.1| PPE family protein [Mycobacterium tuberculosis CTRI-2]
Length=391

 Score =  345 bits (886),  Expect = 6e-93, Method: Compositional matrix adjust.
 Identities = 279/398 (71%), Positives = 307/398 (78%), Gaps = 11/398 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMAMVTAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAF---AALNPATVTAAADAVPAAAAAAGLA  297
             FV N IN A NT AW+V A IP A+FL +A    A +  A     A    A+AAAAGLA
Sbjct  241  PFVANIINSADNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  356
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355

Query  357  VAAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            V  M  M G++ AAKG GAYAGPRYGFKP VMPKQVVV
Sbjct  356  VTGM--MPGMASAAKGTGAYAGPRYGFKPTVMPKQVVV  391


>gi|340626050|ref|YP_004744502.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340004240|emb|CCC43381.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=391

 Score =  345 bits (884),  Expect = 9e-93, Method: Compositional matrix adjust.
 Identities = 279/398 (71%), Positives = 307/398 (78%), Gaps = 11/398 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINS RMYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GP
Sbjct  1    MDFGALPPEINSARMYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASM+MV AAQPYLAWLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAAL
Sbjct  61   ASMAMVAAAQPYLAWLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLG NTPAIMATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA
Sbjct  121  VATNVLGINTPAIMATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q+AAV  AAA + V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL  
Sbjct  181  AQSAAVGSAAATAAVNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLAT  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAF---AALNPATVTAAADAVPAAAAAAGLA  297
             FV N IN AVNT AW+V A IP A+FL +A    A +  A     A    A+AAAAGLA
Sbjct  241  PFVANIINSAVNTAAWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLA  300

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGP  356
             +VTP G+G     ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGP
Sbjct  301  DSVTPAGLG-----ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGP  355

Query  357  VAAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            V  M  M G++ AAK  GAYAGPRYGFKP VMPKQVVV
Sbjct  356  VTGM--MPGMASAAKSTGAYAGPRYGFKPTVMPKQVVV  391


>gi|340627772|ref|YP_004746224.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
 gi|340005962|emb|CCC45129.1| PPE family protein [Mycobacterium canettii CIPT 140010059]
Length=382

 Score =  323 bits (827),  Expect = 5e-86, Method: Compositional matrix adjust.
 Identities = 233/394 (60%), Positives = 271/394 (69%), Gaps = 18/394 (4%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPE+NS RMY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+GP
Sbjct  1    MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS+SM  A QPYL WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L
Sbjct  61   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
             ATN+LGQN  AI ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA
Sbjct  121  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAV  A A+++ +QVGL  LIS++ +AVM FASP+ SAAD       ++ + + L +
Sbjct  181  HQAAAVGQAGASASARQVGLSHLISDVADAVMSFASPVMSAADTG-----LEAVRQFLNL  235

Query  241  T---FVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLA  297
                FV++A +G +   A F  A I N   L  A   ++ A     A A  A A A    
Sbjct  236  DVPLFVESAFHG-LGGVADFATAAIGNMTLLADAMGTVDGAAPGGGAPAAVAHAVAPAGV  294

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPV  357
                    GG +LTA LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+
Sbjct  295  --------GGTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPI  345

Query  358  AAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQ  391
            A MP   G+  AA   GA +GPRYG KPIVMPK 
Sbjct  346  AVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKH  379


>gi|297730553|ref|ZP_06959671.1| PPE family protein [Mycobacterium tuberculosis KZN R506]
 gi|313657882|ref|ZP_07814762.1| PPE family protein [Mycobacterium tuberculosis KZN V2475]
Length=377

 Score =  319 bits (817),  Expect = 6e-85, Method: Compositional matrix adjust.
 Identities = 267/384 (70%), Positives = 295/384 (77%), Gaps = 11/384 (2%)

Query  15   MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  74
            MYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GPASM+MV AAQPYLA
Sbjct  1    MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVTAAQPYLA  60

Query  75   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  134
            WLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAALVATNVLG NTPAIM
Sbjct  61   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  120

Query  135  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  194
            ATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA Q+AAV  AAA + 
Sbjct  121  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  180

Query  195  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT  254
            V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL   FV N IN AVNT 
Sbjct  181  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  240

Query  255  AWFVMATIPNAVFLGHAF---AALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLT  311
            AW+V A IP A+FL +A    A +  A     A    A+AAAAGLA +VTP G+G     
Sbjct  241  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLG-----  295

Query  312  ASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGPVAAMPGMAGISGAA  370
            ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGPV  M  M G++ AA
Sbjct  296  ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM--MPGMASAA  353

Query  371  KGAGAYAGPRYGFKPIVMPKQVVV  394
            KG GAYAGPRYGFKP VMPKQVVV
Sbjct  354  KGTGAYAGPRYGFKPTVMPKQVVV  377


>gi|31793945|ref|NP_856438.1| PPE family protein [Mycobacterium bovis AF2122/97]
 gi|121638649|ref|YP_978873.1| PPE family protein [Mycobacterium bovis BCG str. Pasteur 1173P2]
 gi|224991141|ref|YP_002645830.1| PPE family protein [Mycobacterium bovis BCG str. Tokyo 172]
 15 more sequence titles
 Length=382

 Score =  318 bits (815),  Expect = 9e-85, Method: Compositional matrix adjust.
 Identities = 232/394 (59%), Positives = 270/394 (69%), Gaps = 18/394 (4%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPE+NS RMY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+GP
Sbjct  1    MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS+SM  A QPYL WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L
Sbjct  61   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
             ATN+LGQN  AI ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA
Sbjct  121  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAV  A A+++ +QVGL  LIS++ +AV+ FASP+ SAAD       ++ + + L +
Sbjct  181  HQAAAVGQAGASASARQVGLSHLISDVADAVLSFASPVMSAADTG-----LEAVRQFLNL  235

Query  241  T---FVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLA  297
                FV++A +G +   A F  A I N   L  A   +  A     A A  A A A    
Sbjct  236  DVPLFVESAFHG-LGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGV  294

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPV  357
                    GG +LTA LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+
Sbjct  295  --------GGTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPI  345

Query  358  AAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQ  391
            A MP   G+  AA   GA +GPRYG KPIVMPK 
Sbjct  346  AVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKH  379


>gi|254550024|ref|ZP_05140471.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|289744777|ref|ZP_06504155.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|294995228|ref|ZP_06800919.1| PPE family protein [Mycobacterium tuberculosis 210]
 gi|298524536|ref|ZP_07011945.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A]
 gi|289685305|gb|EFD52793.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|298494330|gb|EFI29624.1| ppe family protein [Mycobacterium tuberculosis 94_M4241A]
Length=377

 Score =  318 bits (815),  Expect = 1e-84, Method: Compositional matrix adjust.
 Identities = 267/384 (70%), Positives = 295/384 (77%), Gaps = 11/384 (2%)

Query  15   MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  74
            MYAGAGA P+MAAGA WNGLA EL TTA+S ESVI +LTTE W+GPASM+MV AAQPYLA
Sbjct  1    MYAGAGAGPMMAAGAAWNGLAAELGTTAASYESVITRLTTESWMGPASMAMVAAAQPYLA  60

Query  75   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  134
            WLTYTAE+AAHA +QAMASAAA+EAA+AMTVPP  VAANRALLAALVATNVLG NTPAIM
Sbjct  61   WLTYTAEAAAHAGSQAMASAAAYEAAYAMTVPPEVVAANRALLAALVATNVLGINTPAIM  120

Query  135  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  194
            ATEA Y EMWAQDALAMYGYAA+S AAG L PL  PSQT N  GLA Q+AAV  AAA + 
Sbjct  121  ATEALYAEMWAQDALAMYGYAAASGAAGMLQPLSPPSQTTNPGGLAAQSAAVGSAAATAA  180

Query  195  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT  254
            V QV +  LIS+LPNAV G ASP+TS  D+ GL GII DI+ LL   FV N IN AVNT 
Sbjct  181  VNQVSVADLISSLPNAVSGLASPVTSVLDSTGLSGIIADIDALLATPFVANIINSAVNTA  240

Query  255  AWFVMATIPNAVFLGHAF---AALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLT  311
            AW+V A IP A+FL +A    A +  A     A    A+AAAAGLA +VTP G+G     
Sbjct  241  AWYVNAAIPTAIFLANALNSGAPVAIAEGAIEAAEGAASAAAAGLADSVTPAGLG-----  295

Query  312  ASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAV-PEEAGPVAAMPGMAGISGAA  370
            ASLGEA+ VG LSVPA WSTAAPA T+G TALEGSGW V  EEAGPV  M  M G++ AA
Sbjct  296  ASLGEATLVGRLSVPAAWSTAAPATTAGATALEGSGWTVAAEEAGPVTGM--MPGMASAA  353

Query  371  KGAGAYAGPRYGFKPIVMPKQVVV  394
            KG GAYAGPRYGFKP VMPKQVVV
Sbjct  354  KGTGAYAGPRYGFKPTVMPKQVVV  377


>gi|289746573|ref|ZP_06505951.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
 gi|289687101|gb|EFD54589.1| PPE family protein [Mycobacterium tuberculosis 02_1987]
Length=402

 Score =  318 bits (814),  Expect = 1e-84, Method: Compositional matrix adjust.
 Identities = 231/394 (59%), Positives = 270/394 (69%), Gaps = 18/394 (4%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            +DFGALPPE+NS RMY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+GP
Sbjct  21   VDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  80

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS+SM  A QPYL WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L
Sbjct  81   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  140

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
             ATN+LGQN  AI ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA
Sbjct  141  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  200

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAV  A A+++ +QVGL  LIS++ +AV+ FASP+ SAAD       ++ + + L +
Sbjct  201  HQAAAVGQAGASASARQVGLSHLISDVADAVLSFASPVMSAADTG-----LEAVRQFLNL  255

Query  241  T---FVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLA  297
                FV++A +G +   A F  A I N   L  A   +  A     A A  A A A    
Sbjct  256  DVPLFVESAFHG-LGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGV  314

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPV  357
                    GG +LTA LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+
Sbjct  315  --------GGTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPI  365

Query  358  AAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQ  391
            A MP   G+  AA   GA +GPRYG KPIVMPK 
Sbjct  366  AVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKH  399


>gi|13377911|gb|AAK20895.1| Rv2770c-like protein [Mycobacterium microti]
 gi|13936234|gb|AAK40252.1| 2770c [Mycobacterium microti]
Length=397

 Score =  317 bits (813),  Expect = 2e-84, Method: Compositional matrix adjust.
 Identities = 231/394 (59%), Positives = 270/394 (69%), Gaps = 18/394 (4%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            +DFGALPPE+NS RMY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+GP
Sbjct  16   VDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  75

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS+SM  A QPYL WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L
Sbjct  76   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  135

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
             ATN+LGQN  AI ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA
Sbjct  136  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  195

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAV  A A+++ +QVGL  LIS++ +AV+ FASP+ SAAD       ++ + + L +
Sbjct  196  HQAAAVGQAGASASARQVGLSHLISDVADAVLSFASPVMSAADTG-----LEAVRQFLNL  250

Query  241  T---FVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLA  297
                FV++A +G +   A F  A I N   L  A   +  A     A A  A A A    
Sbjct  251  DVPLFVESAFHG-LGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGV  309

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPV  357
                    GG +LTA LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+
Sbjct  310  --------GGTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPI  360

Query  358  AAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQ  391
            A MP   G+  AA   GA +GPRYG KPIVMPK 
Sbjct  361  AVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKH  394


>gi|57117024|ref|YP_177677.1| PPE family protein [Mycobacterium tuberculosis H37Rv]
 gi|148662612|ref|YP_001284135.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|148823958|ref|YP_001288712.1| PPE family protein [Mycobacterium tuberculosis F11]
 8 more sequence titles
 Length=382

 Score =  317 bits (813),  Expect = 2e-84, Method: Compositional matrix adjust.
 Identities = 232/394 (59%), Positives = 269/394 (69%), Gaps = 18/394 (4%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPE+NS RMY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+GP
Sbjct  1    MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS+SM  A QPYL WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L
Sbjct  61   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
             ATN+LGQN  AI ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA
Sbjct  121  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAV  A A++  +QVGL  LIS++ +AV+ FASP+ SAAD       ++ + + L +
Sbjct  181  HQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAADTG-----LEAVRQFLNL  235

Query  241  T---FVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLA  297
                FV++A +G +   A F  A I N   L  A   +  A     A A  A A A    
Sbjct  236  DVPLFVESAFHG-LGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGV  294

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPV  357
                    GG +LTA LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+
Sbjct  295  --------GGTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPI  345

Query  358  AAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQ  391
            A MP   G+  AA   GA +GPRYG KPIVMPK 
Sbjct  346  AVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKH  379


>gi|15842308|ref|NP_337345.1| PPE family protein [Mycobacterium tuberculosis CDC1551]
 gi|253798147|ref|YP_003031148.1| PPE family protein [Mycobacterium tuberculosis KZN 1435]
 gi|254232868|ref|ZP_04926195.1| PPE family protein [Mycobacterium tuberculosis C]
 10 more sequence titles
 Length=402

 Score =  316 bits (810),  Expect = 4e-84, Method: Compositional matrix adjust.
 Identities = 231/394 (59%), Positives = 269/394 (69%), Gaps = 18/394 (4%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            +DFGALPPE+NS RMY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+GP
Sbjct  21   VDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGP  80

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS+SM  A QPYL WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L
Sbjct  81   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  140

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
             ATN+LGQN  AI ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA
Sbjct  141  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  200

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAV  A A++  +QVGL  LIS++ +AV+ FASP+ SAAD       ++ + + L +
Sbjct  201  HQAAAVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAADTG-----LEAVRQFLNL  255

Query  241  T---FVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLA  297
                FV++A +G +   A F  A I N   L  A   +  A     A A  A A A    
Sbjct  256  DVPLFVESAFHG-LGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGV  314

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPV  357
                    GG +LTA LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+
Sbjct  315  --------GGTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPI  365

Query  358  AAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQ  391
            A MP   G+  AA   GA +GPRYG KPIVMPK 
Sbjct  366  AVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKH  399


>gi|289444315|ref|ZP_06434059.1| PPE family protein [Mycobacterium tuberculosis T46]
 gi|289570949|ref|ZP_06451176.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289751427|ref|ZP_06510805.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289754876|ref|ZP_06514254.1| PPE family protein [Mycobacterium tuberculosis EAS054]
 gi|289417234|gb|EFD14474.1| PPE family protein [Mycobacterium tuberculosis T46]
 gi|289544703|gb|EFD48351.1| PPE family protein [Mycobacterium tuberculosis T17]
 gi|289692014|gb|EFD59443.1| PPE family protein [Mycobacterium tuberculosis T92]
 gi|289695463|gb|EFD62892.1| PPE family protein [Mycobacterium tuberculosis EAS054]
Length=382

 Score =  315 bits (807),  Expect = 9e-84, Method: Compositional matrix adjust.
 Identities = 231/394 (59%), Positives = 269/394 (69%), Gaps = 18/394 (4%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPE+NS RMY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+ P
Sbjct  1    MDFGALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMVP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS+SM  A QPYL WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L
Sbjct  61   ASLSMAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAEL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
             ATN+LGQN  AI ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA
Sbjct  121  TATNILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAV  A A+++ +QVGL  LIS++ +AV+ FASP+ SAAD       ++ + + L +
Sbjct  181  HQAAAVGQAGASASARQVGLSHLISDVADAVLSFASPVMSAADTG-----LEAVRQFLNL  235

Query  241  T---FVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLA  297
                FV++A +G +   A F  A I N   L  A   +  A     A A  A A A    
Sbjct  236  DVPLFVESAFHG-LGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGV  294

Query  298  HTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPV  357
                    GG +LTA LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+
Sbjct  295  --------GGTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPI  345

Query  358  AAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPKQ  391
            A MP   G+  AA   GA +GPRYG KPIVMPK 
Sbjct  346  AVMPPAPGMVVAANSVGADSGPRYGVKPIVMPKH  379


>gi|308374682|ref|ZP_07436980.2| LOW QUALITY PROTEIN: PPE family protein [Mycobacterium tuberculosis 
SUMu006]
 gi|308341059|gb|EFP29910.1| LOW QUALITY PROTEIN: PPE family protein [Mycobacterium tuberculosis 
SUMu006]
Length=378

 Score =  307 bits (787),  Expect = 2e-81, Method: Compositional matrix adjust.
 Identities = 228/390 (59%), Positives = 265/390 (68%), Gaps = 18/390 (4%)

Query  5    ALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMS  64
            ALPPE+NS RMY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+GPAS+S
Sbjct  1    ALPPEVNSARMYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLS  60

Query  65   MVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATN  124
            M  A QPYL WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L ATN
Sbjct  61   MAAAVQPYLVWLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATN  120

Query  125  VLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAA  184
            +LGQN  AI ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA QAA
Sbjct  121  ILGQNVSAIAATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLAHQAA  180

Query  185  AVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGIT---  241
            AV  A A++  +QVGL  LIS++ +AV+ FASP+ SAAD       ++ + + L +    
Sbjct  181  AVGQAGASAFARQVGLSHLISDVADAVLSFASPVMSAADTG-----LEAVRQFLNLDVPL  235

Query  242  FVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVT  301
            FV++A +G +   A F  A I N   L  A   +  A     A A  A A A        
Sbjct  236  FVESAFHG-LGGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGV----  290

Query  302  PVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAMP  361
                GG +LTA LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+A MP
Sbjct  291  ----GGTALTADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPIAVMP  345

Query  362  GMAGISGAAKGAGAYAGPRYGFKPIVMPKQ  391
               G+  AA   GA +GPRYG KPIVMPK 
Sbjct  346  PAPGMVVAANSVGADSGPRYGVKPIVMPKH  375


>gi|183981960|ref|YP_001850251.1| PPE family protein, PPE44 [Mycobacterium marinum M]
 gi|183175286|gb|ACC40396.1| PPE family protein, PPE44 [Mycobacterium marinum M]
Length=377

 Score =  305 bits (780),  Expect = 1e-80, Method: Compositional matrix adjust.
 Identities = 233/394 (60%), Positives = 277/394 (71%), Gaps = 21/394 (5%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            +DFGALPPEINS RMY GAGAAPL+ A A WN +AVELST AS++ESVI +L+++QWLG 
Sbjct  5    VDFGALPPEINSARMYFGAGAAPLLGAAAAWNDIAVELSTAASAIESVITRLSSDQWLGT  64

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS+SM  AAQP LAWL+YTAES+A AAAQA AS AAFE AFAMTVPPAEVAANRA LA L
Sbjct  65   ASLSMAAAAQPLLAWLSYTAESSALAAAQAAASVAAFETAFAMTVPPAEVAANRARLAEL  124

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            +ATN+ GQN PAI ATEA YGEMWAQDA AMYGYAAS A A RLNPL  PS+T N  G+A
Sbjct  125  MATNIFGQNVPAIAATEARYGEMWAQDASAMYGYAASCAGAVRLNPLTRPSETTNPGGIA  184

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAVSHAAA+ +VQQ G  +LIS + +AVM  ++P+TS+     LG  I+DI  L   
Sbjct  185  RQAAAVSHAAASVSVQQAGFENLISTVSDAVMSLSAPVTSSPHVTSLGAFIEDIIFLDIP  244

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
             FV++A +G   T  +   AT+  A  L    +A    T T+A    PAAAA + LA TV
Sbjct  245  RFVESAFHGLGATADY---ATMIAANLLTLQTSA---NTATSAGGVAPAAAAGSALAQTV  298

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            T  GV         G+ASSVG LSVP GW+TAAPA T G  + +G+GWAVP+E      +
Sbjct  299  TSAGV---------GDASSVGALSVPVGWTTAAPAATGGAAS-DGTGWAVPDE-----DV  343

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            P  AG+     GAGA  GPRYG KP VMPK+V+V
Sbjct  344  PSPAGMVAGTNGAGARPGPRYGVKPRVMPKKVLV  377


>gi|294994137|ref|ZP_06799828.1| PPE family protein [Mycobacterium tuberculosis 210]
 gi|339295620|gb|AEJ47731.1| Rv2770c-like protein [Mycobacterium tuberculosis CCDC5079]
 gi|339299237|gb|AEJ51347.1| Rv2770c-like protein [Mycobacterium tuberculosis CCDC5180]
Length=368

 Score =  290 bits (743),  Expect = 2e-76, Method: Compositional matrix adjust.
 Identities = 220/380 (58%), Positives = 257/380 (68%), Gaps = 18/380 (4%)

Query  15   MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  74
            MY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+GPAS+SM  A QPYL 
Sbjct  1    MYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLSMAAAVQPYLV  60

Query  75   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  134
            WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L ATN+LGQN  AI 
Sbjct  61   WLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATNILGQNVSAIA  120

Query  135  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  194
            ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA QAAAV  A A+++
Sbjct  121  ATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLAHQAAAVGQAGASAS  180

Query  195  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGIT---FVQNAINGAV  251
             +QVGL  LIS++ +AV+ FASP+ SAAD       ++ + + L +    FV++A +G +
Sbjct  181  ARQVGLSHLISDVADAVLSFASPVMSAADTG-----LEAVRQFLNLDVPLFVESAFHG-L  234

Query  252  NTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLT  311
               A F  A I N   L  A   +  A     A A  A A A            GG +LT
Sbjct  235  GGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGV--------GGTALT  286

Query  312  ASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAMPGMAGISGAAK  371
            A LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+A MP   G+  AA 
Sbjct  287  ADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPIAVMPPAPGMVVAAN  345

Query  372  GAGAYAGPRYGFKPIVMPKQ  391
              GA +GPRYG KPIVMPK 
Sbjct  346  SVGADSGPRYGVKPIVMPKH  365


>gi|289448425|ref|ZP_06438169.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
 gi|289421383|gb|EFD18584.1| PPE family protein [Mycobacterium tuberculosis CPHL_A]
Length=232

 Score =  290 bits (742),  Expect = 3e-76, Method: Compositional matrix adjust.
 Identities = 149/149 (100%), Positives = 149/149 (100%), Gaps = 0/149 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP
Sbjct  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL
Sbjct  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDAL  149
            VATNVLGQNTPAIMATEAHYGEMWAQDAL
Sbjct  121  VATNVLGQNTPAIMATEAHYGEMWAQDAL  149


>gi|167968599|ref|ZP_02550876.1| PPE family protein [Mycobacterium tuberculosis H37Ra]
 gi|254551829|ref|ZP_05142276.1| PPE family protein [Mycobacterium tuberculosis '98-R604 INH-RIF-EM']
 gi|297635379|ref|ZP_06953159.1| PPE family protein [Mycobacterium tuberculosis KZN 4207]
 14 more sequence titles
 Length=368

 Score =  289 bits (739),  Expect = 7e-76, Method: Compositional matrix adjust.
 Identities = 220/380 (58%), Positives = 256/380 (68%), Gaps = 18/380 (4%)

Query  15   MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  74
            MY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+GPAS+SM  A QPYL 
Sbjct  1    MYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLSMAAAVQPYLV  60

Query  75   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  134
            WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L ATN+LGQN  AI 
Sbjct  61   WLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATNILGQNVSAIA  120

Query  135  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  194
            ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA QAAAV  A A++ 
Sbjct  121  ATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLAHQAAAVGQAGASAF  180

Query  195  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGIT---FVQNAINGAV  251
             +QVGL  LIS++ +AV+ FASP+ SAAD       ++ + + L +    FV++A +G +
Sbjct  181  ARQVGLSHLISDVADAVLSFASPVMSAADTG-----LEAVRQFLNLDVPLFVESAFHG-L  234

Query  252  NTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLT  311
               A F  A I N   L  A   +  A     A A  A A A            GG +LT
Sbjct  235  GGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGV--------GGTALT  286

Query  312  ASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAMPGMAGISGAAK  371
            A LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+A MP   G+  AA 
Sbjct  287  ADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPIAVMPPAPGMVVAAN  345

Query  372  GAGAYAGPRYGFKPIVMPKQ  391
              GA +GPRYG KPIVMPK 
Sbjct  346  SVGADSGPRYGVKPIVMPKH  365


>gi|306777051|ref|ZP_07415388.1| PPE family protein [Mycobacterium tuberculosis SUMu001]
 gi|306973166|ref|ZP_07485827.1| PPE family protein [Mycobacterium tuberculosis SUMu010]
 gi|307080875|ref|ZP_07490045.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
 gi|308214561|gb|EFO73960.1| PPE family protein [Mycobacterium tuberculosis SUMu001]
 gi|308357429|gb|EFP46280.1| PPE family protein [Mycobacterium tuberculosis SUMu010]
 gi|308361380|gb|EFP50231.1| PPE family protein [Mycobacterium tuberculosis SUMu011]
Length=368

 Score =  288 bits (736),  Expect = 1e-75, Method: Compositional matrix adjust.
 Identities = 219/380 (58%), Positives = 255/380 (68%), Gaps = 18/380 (4%)

Query  15   MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  74
            MY GAGAA L+AA A WNG+AVE+ST ASSV SVI +L+TE W+GPAS+SM    QPYL 
Sbjct  1    MYGGAGAADLLAAAAAWNGIAVEVSTAASSVGSVITRLSTEHWMGPASLSMAATVQPYLV  60

Query  75   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  134
            WLT TAES+A AAAQAMASAAAFE AFA+TVPPAEV ANRALLA L ATN+LGQN  AI 
Sbjct  61   WLTCTAESSALAAAQAMASAAAFETAFALTVPPAEVVANRALLAELTATNILGQNVSAIA  120

Query  135  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  194
            ATEA YGEMWAQDA AMYGYAA+SA A RLNPL  PS   N AGLA QAAAV  A A++ 
Sbjct  121  ATEARYGEMWAQDASAMYGYAAASAVAARLNPLTRPSHITNPAGLAHQAAAVGQAGASAF  180

Query  195  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGIT---FVQNAINGAV  251
             +QVGL  LIS++ +AV+ FASP+ SAAD       ++ + + L +    FV++A +G +
Sbjct  181  ARQVGLSHLISDVADAVLSFASPVMSAADTG-----LEAVRQFLNLDVPLFVESAFHG-L  234

Query  252  NTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLT  311
               A F  A I N   L  A   +  A     A A  A A A            GG +LT
Sbjct  235  GGVADFATAAIGNMTLLADAMGTVGGAAPGGGAAAAVAHAVAPAGV--------GGTALT  286

Query  312  ASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAMPGMAGISGAAK  371
            A LG AS VG LSVPA WSTAA   T+   AL+G+GWAVPEE GP+A MP   G+  AA 
Sbjct  287  ADLGNASVVGRLSVPASWSTAA-PATAAGAALDGTGWAVPEEDGPIAVMPPAPGMVVAAN  345

Query  372  GAGAYAGPRYGFKPIVMPKQ  391
              GA +GPRYG KPIVMPK 
Sbjct  346  SVGADSGPRYGVKPIVMPKH  365


>gi|118617719|ref|YP_906051.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118569829|gb|ABL04580.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=373

 Score =  287 bits (734),  Expect = 2e-75, Method: Compositional matrix adjust.
 Identities = 231/394 (59%), Positives = 274/394 (70%), Gaps = 21/394 (5%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDFGALPPEINS RMY GAGAAPL+ A A WN +AVELST AS++ESVI +L+++QWLG 
Sbjct  1    MDFGALPPEINSARMYFGAGAAPLLGAAAAWNDIAVELSTAASAIESVITRLSSDQWLGT  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS+SM  AAQP LAWL+YTAES+A AAAQA AS AAFE AFAMTVPPAEVAANRA LAAL
Sbjct  61   ASLSMAAAAQPLLAWLSYTAESSALAAAQAAASVAAFETAFAMTVPPAEVAANRARLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            +ATN+ GQN PAI ATEA YGEMWAQDA AMYGYAAS A A RLNPL  PS+T N  G+A
Sbjct  121  MATNIFGQNVPAIAATEARYGEMWAQDASAMYGYAASCAGAVRLNPLTRPSETTNPGGIA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QA AVSHAAA+ +VQQ G  +LIS + +AV   + P+TS+     LG  I+DI  L   
Sbjct  181  SQAVAVSHAAASVSVQQAGFENLISTVSDAVTSLSGPVTSSPHVTSLGAFIEDIIFLDIP  240

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
             FV++A +G +  TA +      N + L       +  T T+A    PAAAA + LA TV
Sbjct  241  RFVESAFHG-LGATADYATMIAANLLTL-----QTSANTATSAGGVAPAAAAGSALAQTV  294

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            T  GV         G+ASSVG LSVP GW+TAAPA T G  + +G+GWAVP+E      +
Sbjct  295  TSAGV---------GDASSVGALSVPVGWTTAAPAATGGAAS-DGTGWAVPDE-----DV  339

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
            P  AG+     GAGA  GPRYG KP VMPK+V+V
Sbjct  340  PSPAGMVAGTNGAGARPGPRYGVKPRVMPKKVLV  373


>gi|118464457|ref|YP_880591.1| PPE family protein [Mycobacterium avium 104]
 gi|118165744|gb|ABK66641.1| ppe family protein [Mycobacterium avium 104]
Length=383

 Score =  261 bits (668),  Expect = 1e-67, Method: Compositional matrix adjust.
 Identities = 200/394 (51%), Positives = 243/394 (62%), Gaps = 13/394 (3%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
             DFGALPPE+NSTRMY GAGAAP+MAA A ++ LA ELSTTA++ +S I  LT E+W+GP
Sbjct  3    FDFGALPPEVNSTRMYTGAGAAPMMAAAAAFSNLADELSTTAAATQSAIANLTGEEWMGP  62

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ++ +MV A QPY+ W+  TA     AAAQAMASAAA+E AFAMTVPPA VAANRA LAAL
Sbjct  63   SAAAMVTAVQPYVQWMHTTAGQLQQAAAQAMASAAAYETAFAMTVPPALVAANRAQLAAL  122

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            +A+NVLGQN  AI ATEA YGEMWAQDA AMYGYAASSA AG+L+PL +P+ T    GL 
Sbjct  123  IASNVLGQNAAAIAATEAQYGEMWAQDAAAMYGYAASSATAGKLSPLTSPAPTNQPGGLG  182

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAVS  A A++ Q  GL   ++N+PN V   A+P    AD  GL      ++ LLG 
Sbjct  183  AQAAAVS-GATATSAQTSGLQGTVANVPNVVRTLAAP----ADPPGLSA----LDNLLGN  233

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
              V N  N   N  +W V  TI + +   H       A V           A  G A   
Sbjct  234  PVVNNVGNAGFNVVSWNVFNTIVSNILYNHTLDTAAAAGVAGEVGGAVGGGALVGAAAPA  293

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            T  GVG A + AS+G A++VG LS PA WS  AP      T +  + WA P E    A  
Sbjct  294  T-AGVGAAPVLASMGSAATVGELSTPATWS--APTPEPAATTVGATEWASPAEEPHTAWA  350

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
             GM  ++ A +G G   GPRYG KP VMP ++ V
Sbjct  351  TGMPAVASAGRG-GYGMGPRYGVKPKVMPTRLPV  383


>gi|212595937|gb|ACJ35536.1| PPE10 [Mycobacterium avium subsp. avium]
Length=383

 Score =  260 bits (664),  Expect = 3e-67, Method: Compositional matrix adjust.
 Identities = 199/394 (51%), Positives = 243/394 (62%), Gaps = 13/394 (3%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
             DFGALPPE+NSTRMY GAGAAP+MAA A ++ LA ELSTTA++ +S I  LT E+W+GP
Sbjct  3    FDFGALPPEVNSTRMYTGAGAAPMMAAAAAFSNLADELSTTAAATQSAIANLTGEEWMGP  62

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ++ +MV A QPY+ W+  TA     AAAQAMASAAA+E AFAMTVPPA VAANRA LAAL
Sbjct  63   SAAAMVTAVQPYVQWMHTTAGQLQQAAAQAMASAAAYETAFAMTVPPALVAANRAQLAAL  122

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            +A+NVLGQN  AI ATEA YGEMWAQDA AMYGYAASSA AG+L+PL +P+ T    GL 
Sbjct  123  IASNVLGQNAAAIAATEAQYGEMWAQDAAAMYGYAASSATAGKLSPLTSPAPTNQPGGLG  182

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAVS  A A++ Q  GL   ++N+PN V   A+P    AD  GL      ++ LLG 
Sbjct  183  AQAAAVS-GATATSAQTSGLQGTVANVPNVVRTLAAP----ADPPGLSA----LDNLLGN  233

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
              V N  N   +  +W V  TI + +   H       A V           A  G A   
Sbjct  234  PVVNNVGNAGFDVVSWNVFNTIVSNILYNHTLDTAAAAGVAGEVGGAVGGGALVGAAAPA  293

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            T  GVG A + AS+G A++VG LS PA WS  AP      T +  + WA P E    A  
Sbjct  294  T-AGVGAAPVLASMGSAATVGELSTPATWS--APTPEPAATTVGATEWASPAEEPHTAWA  350

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
             GM  ++ A +G G   GPRYG KP VMP ++ V
Sbjct  351  TGMPAVASAGRG-GYGMGPRYGVKPKVMPTRLPV  383


>gi|41408673|ref|NP_961509.1| hypothetical protein MAP2575c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41397031|gb|AAS04892.1| hypothetical protein MAP_2575c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336458621|gb|EGO37586.1| PPE family protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=383

 Score =  259 bits (662),  Expect = 5e-67, Method: Compositional matrix adjust.
 Identities = 199/394 (51%), Positives = 243/394 (62%), Gaps = 13/394 (3%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
             DFGALPPE+NSTRMY GAGAAP+MAA A ++ LA ELSTTA++ +S I  LT E+W+GP
Sbjct  3    FDFGALPPEVNSTRMYTGAGAAPMMAAAAAFSNLADELSTTAAATQSAIANLTGEEWMGP  62

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            ++ +MV A QPY+ W+  TA     AAAQAMASAAA+E AFAMTVPPA VAANRA LAAL
Sbjct  63   SAAAMVTAVQPYVQWMHTTAGQLQQAAAQAMASAAAYETAFAMTVPPALVAANRAQLAAL  122

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            +A+NVLGQN  AI ATEA YGEMWAQDA AMYGYAASSA AG+L+PL +P+ T    GL 
Sbjct  123  IASNVLGQNAAAIAATEAQYGEMWAQDAAAMYGYAASSATAGKLSPLTSPAPTNQPGGLG  182

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             QAAAVS  A A++ Q  GL   ++N+PN V   A+P    AD  GL      ++ LLG 
Sbjct  183  AQAAAVS-GATATSAQTSGLQGTVANVPNVVRTLAAP----ADPPGLTA----LDNLLGN  233

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
              V N  N   +  +W V  TI + +   H       A V           A  G A   
Sbjct  234  PVVNNVGNAGFDVVSWNVFNTIVSNILYNHTLDTAAAAGVAGEVGGAVGGGALVGAAAPA  293

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
            T  GVG A + AS+G A++VG LS PA WS  AP      T +  + WA P E    A  
Sbjct  294  T-AGVGAAPVLASMGSAATVGELSTPATWS--APTPEPAATTVGATEWASPAEEPHTAWA  350

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
             GM  ++ A +G G   GPRYG KP VMP ++ V
Sbjct  351  TGMPAVASAGRG-GYGMGPRYGVKPKVMPTRLPV  383


>gi|240173300|ref|ZP_04751958.1| PPE family protein [Mycobacterium kansasii ATCC 12478]
Length=369

 Score =  250 bits (638),  Expect = 3e-64, Method: Compositional matrix adjust.
 Identities = 221/378 (59%), Positives = 255/378 (68%), Gaps = 11/378 (2%)

Query  15   MYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGPASMSMVVAAQPYLA  74
            MYAGAGAA L+AA A WNG+AVELST AS  ES++ +L TE WLGPAS+SM  AAQP +A
Sbjct  1    MYAGAGAAELVAAAAAWNGIAVELSTAASCFESIVTRLRTEPWLGPASLSMAAAAQPLVA  60

Query  75   WLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAALVATNVLGQNTPAIM  134
            WLT TAES+A AAAQAMASAAAFEA  AMTV P EVAANRA LA LVATN+LGQN PAI 
Sbjct  61   WLTDTAESSALAAAQAMASAAAFEAGRAMTVAPGEVAANRAQLAELVATNILGQNMPAIA  120

Query  135  ATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLAGQAAAVSHAAAAST  194
            A EA YGEMWAQDA AMYGYAA+SA AGRLNPL  PS   N AG+A    A +   AA +
Sbjct  121  AVEARYGEMWAQDAAAMYGYAAASAVAGRLNPLTGPSAVTNPAGIA--GQAAAVGQAAGS  178

Query  195  VQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGITFVQNAINGAVNTT  254
            V Q GL +LISNLPNAVM  ASP  S A  +GL  ++  +     + FV +A +G     
Sbjct  179  VPQTGLNNLISNLPNAVMSLASPAPSEAQVSGLNAVLSFLTNPNPL-FVDHAWHGVSGVL  237

Query  255  AWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLTASL  314
            A F MA       L  +    + AT   A+ A P AA  A  A TVTP GVG   + A L
Sbjct  238  ADFDMA-------LTTSSDGADVATGVTASGAGPVAATTAASARTVTPAGVGATPIVAGL  290

Query  315  GEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAMPGMAGISGAAKGAG  374
            G ASSVG LSVPA WSTAAPA+T+   ++ G+GWAVPEE   +AA P   G+  AA GAG
Sbjct  291  GTASSVGRLSVPASWSTAAPAVTADIASV-GTGWAVPEEDAAIAAAPFAPGMVVAADGAG  349

Query  375  AYAGPRYGFKPIVMPKQV  392
            A  GPRYG +P VMP+ V
Sbjct  350  AGVGPRYGVRPTVMPRHV  367


>gi|254774062|ref|ZP_05215578.1| hypothetical protein MaviaA2_05233 [Mycobacterium avium subsp. 
avium ATCC 25291]
 gi|212595906|gb|ACJ35532.1| PPE6 [Mycobacterium avium subsp. avium]
 gi|212595970|gb|ACJ35540.1| PPE15 [Mycobacterium avium subsp. avium]
Length=382

 Score =  248 bits (633),  Expect = 1e-63, Method: Compositional matrix adjust.
 Identities = 220/408 (54%), Positives = 263/408 (65%), Gaps = 42/408 (10%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            +DF A+PPEI S  MYAGAG+ PLMAA   +  L+ E+S+TAS  ES+I  LTTEQW G 
Sbjct  3    LDFAAVPPEITSALMYAGAGSGPLMAAATAYANLSAEVSSTASQWESIISLLTTEQWTGG  62

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
             S +   AAQP +++LT TA +   A+AQA ASAAA+EAAFA TVPP  +AANR+LLA L
Sbjct  63   GSAAAAAAAQPIVSYLTTTAAALEQASAQATASAAAYEAAFAATVPPPVIAANRSLLATL  122

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATN LG N+ AI ATEA Y EMW QDA  M  Y A+SAAAG L P+   + T N     
Sbjct  123  VATNFLGVNSAAIAATEAQYAEMWVQDATMMATYQAASAAAGVLQPVTPLTSTTN----P  178

Query  181  GQAAAVSHAAAA-----STVQQVGLG--SLISNLPNAVMGFASPLTSAADAAGLGGIIQD  233
            G AAAV + A A     ST Q  GL   SLI++ P                    G++Q 
Sbjct  179  GAAAAVDNGAVAFDATNSTAQTAGLDLSSLITSPPT------------------DGLLQS  220

Query  234  IEELLGITFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAA  293
            I++LLG     NA NGA+NT AW+V ATIPNAV LG     + PA   +  D+V  AA A
Sbjct  221  IDDLLGTPSFLNATNGAINTAAWWVCATIPNAVSLGKTLGTV-PAIPFSLTDSVAPAAGA  279

Query  294  AGLAHTVTP---VG-VGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTA--LEGSG  347
            A     +TP   VG V GA  +A++GEAS+VGGLSVPA WS AAPA +  ++A  LEGSG
Sbjct  280  A-----ITPGMMVGSVTGAGASAAVGEASAVGGLSVPASWSAAAPATSLASSAAPLEGSG  334

Query  348  WAVPEEAGPVAAMPGMAGISGAAKGAGAY-AGPRYGFKPIVMPKQVVV  394
            W V  EA PV AMPGM G + AAKGAGAY +GPRYGFKPIVMPKQVVV
Sbjct  335  WTVASEAEPVTAMPGMPGAAAAAKGAGAYGSGPRYGFKPIVMPKQVVV  382


>gi|336461476|gb|EGO40346.1| PPE-repeat containing protein [Mycobacterium avium subsp. paratuberculosis 
S397]
Length=690

 Score =  248 bits (632),  Expect = 2e-63, Method: Compositional matrix adjust.
 Identities = 220/408 (54%), Positives = 263/408 (65%), Gaps = 42/408 (10%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            +DF A+PPEI S  MYAGAG+ PLMAA   +  L+ E+S+TAS  ES+I  LTTEQW G 
Sbjct  311  LDFAAVPPEITSALMYAGAGSGPLMAAATAYANLSAEVSSTASQWESIISLLTTEQWTGG  370

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
             S +   AAQP +++LT TA +   A+AQA ASAAA+EAAFA TVPP  +AANR+LLA L
Sbjct  371  GSAAAAAAAQPIVSYLTTTAAALEQASAQATASAAAYEAAFAATVPPPVIAANRSLLATL  430

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATN LG N+ AI ATEA Y EMW QDA  M  Y A+SAAAG L P+   + T N     
Sbjct  431  VATNFLGVNSAAIAATEAQYAEMWVQDATMMATYQAASAAAGVLQPVTPLTSTTN----P  486

Query  181  GQAAAVSHAAAA-----STVQQVGLG--SLISNLPNAVMGFASPLTSAADAAGLGGIIQD  233
            G AAAV + A A     ST Q  GL   SLI++ P                    G++Q 
Sbjct  487  GAAAAVDNGAVAFDATNSTAQTAGLDLSSLITSPPT------------------DGLLQS  528

Query  234  IEELLGITFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAA  293
            I++LLG     NA NGA+NT AW+V ATIPNAV LG     + PA   +  D+V  AA A
Sbjct  529  IDDLLGTPSFLNATNGAINTAAWWVCATIPNAVSLGKTLGTV-PAIPFSLTDSVAPAAGA  587

Query  294  AGLAHTVTP---VG-VGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTA--LEGSG  347
            A     +TP   VG V GA  +A++GEAS+VGGLSVPA WS AAPA +  ++A  LEGSG
Sbjct  588  A-----ITPGMMVGSVTGAGASAAVGEASAVGGLSVPASWSAAAPATSLASSAAPLEGSG  642

Query  348  WAVPEEAGPVAAMPGMAGISGAAKGAGAY-AGPRYGFKPIVMPKQVVV  394
            W V  EA PV AMPGM G + AAKGAGAY +GPRYGFKPIVMPKQVVV
Sbjct  643  WTVASEAEPVTAMPGMPGAAAAAKGAGAYGSGPRYGFKPIVMPKQVVV  690


>gi|41407101|ref|NP_959937.1| hypothetical protein MAP1003c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41395452|gb|AAS03320.1| PE [Mycobacterium avium subsp. paratuberculosis K-10]
Length=696

 Score =  246 bits (629),  Expect = 3e-63, Method: Compositional matrix adjust.
 Identities = 220/408 (54%), Positives = 263/408 (65%), Gaps = 42/408 (10%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            +DF A+PPEI S  MYAGAG+ PLMAA   +  L+ E+S+TAS  ES+I  LTTEQW G 
Sbjct  317  LDFAAVPPEITSALMYAGAGSGPLMAAATAYANLSAEVSSTASQWESIISLLTTEQWTGG  376

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
             S +   AAQP +++LT TA +   A+AQA ASAAA+EAAFA TVPP  +AANR+LLA L
Sbjct  377  GSAAAAAAAQPIVSYLTTTAAALEQASAQATASAAAYEAAFAATVPPPVIAANRSLLATL  436

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATN LG N+ AI ATEA Y EMW QDA  M  Y A+SAAAG L P+   + T N     
Sbjct  437  VATNFLGVNSAAIAATEAQYAEMWVQDATMMATYQAASAAAGVLQPVTPLTSTTN----P  492

Query  181  GQAAAVSHAAAA-----STVQQVGLG--SLISNLPNAVMGFASPLTSAADAAGLGGIIQD  233
            G AAAV + A A     ST Q  GL   SLI++ P                    G++Q 
Sbjct  493  GAAAAVDNGAVAFDATNSTAQTAGLDLSSLITSPPT------------------DGLLQS  534

Query  234  IEELLGITFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAA  293
            I++LLG     NA NGA+NT AW+V ATIPNAV LG     + PA   +  D+V  AA A
Sbjct  535  IDDLLGTPSFLNATNGAINTAAWWVCATIPNAVSLGKTLGTV-PAIPFSLTDSVAPAAGA  593

Query  294  AGLAHTVTP---VG-VGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTA--LEGSG  347
            A     +TP   VG V GA  +A++GEAS+VGGLSVPA WS AAPA +  ++A  LEGSG
Sbjct  594  A-----ITPGMMVGSVTGAGASAAVGEASAVGGLSVPASWSAAAPATSLASSAAPLEGSG  648

Query  348  WAVPEEAGPVAAMPGMAGISGAAKGAGAY-AGPRYGFKPIVMPKQVVV  394
            W V  EA PV AMPGM G + AAKGAGAY +GPRYGFKPIVMPKQVVV
Sbjct  649  WTVASEAEPVTAMPGMPGAAAAAKGAGAYGSGPRYGFKPIVMPKQVVV  696


>gi|240170332|ref|ZP_04748991.1| PPE family protein, PPE15 [Mycobacterium kansasii ATCC 12478]
Length=261

 Score =  243 bits (620),  Expect = 4e-62, Method: Compositional matrix adjust.
 Identities = 191/260 (74%), Positives = 215/260 (83%), Gaps = 0/260 (0%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDF ALPPEINS RMYAGAGA PL+AA A WNGLA+EL+TTA+S+ES++  LT EQWLGP
Sbjct  1    MDFAALPPEINSGRMYAGAGAGPLLAAAAAWNGLALELNTTAASIESIVTLLTGEQWLGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS+SM  AAQPY+AWLTYT  SA HA AQAMASAAA+EAAFA TVPP  +AANRALLAAL
Sbjct  61   ASLSMAAAAQPYIAWLTYTGASAEHAGAQAMASAAAYEAAFAATVPPPIIAANRALLAAL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATN LG NTPAIMATEAHY EMWAQDA+AMY YAASSA +G LNPL TPSQ+ N  GLA
Sbjct  121  VATNFLGINTPAIMATEAHYMEMWAQDAMAMYAYAASSANSGTLNPLTTPSQSTNPGGLA  180

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q+AAV  AAAA+TV QVGL SLI++LPNAVM  ASP+TS ADA GL GI+Q I++LL I
Sbjct  181  AQSAAVGQAAAAATVNQVGLSSLITDLPNAVMSLASPITSVADATGLTGIMQSIDDLLAI  240

Query  241  TFVQNAINGAVNTTAWFVMA  260
              V N +NG +NT AWFVMA
Sbjct  241  PMVANILNGGINTAAWFVMA  260


>gi|183982688|ref|YP_001850979.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
 gi|183176014|gb|ACC41124.1| PPE family protein, PPE31_1 [Mycobacterium marinum M]
Length=422

 Score =  241 bits (616),  Expect = 1e-61, Method: Compositional matrix adjust.
 Identities = 189/422 (45%), Positives = 236/422 (56%), Gaps = 41/422 (9%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDF ALPPEINS RMY+G G+AP++AA   W+GLA EL +TA++ E+VI  LT + WLGP
Sbjct  1    MDFAALPPEINSIRMYSGPGSAPMLAAVTAWDGLAAELRSTAAAYETVIAVLTGDGWLGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS SM  A  PYLAW+  T   A   A QA A+A AFEAAFAMTVPPA+VAANR  L  L
Sbjct  61   ASESMEAAVFPYLAWMNITGMQAEQTARQAAAAAGAFEAAFAMTVPPAQVAANRTQLQTL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATN+LGQNTPAI ATEA YGEMWAQDA AMYGYA  SAAA  L     P+QT + +GLA
Sbjct  121  VATNLLGQNTPAIAATEAAYGEMWAQDAAAMYGYAVGSAAASTLTQFTQPAQTTDPSGLA  180

Query  181  GQAAAVSHAAAAS--TVQQVGLGSLISNLPNAVMGFASP-LTSAADAAGLGGIIQDIEEL  237
             Q+AAV+ A  ++   + Q  L  L+S +P ++ G ASP   S  DA    G++  +   
Sbjct  181  SQSAAVTQAVGSTVGNLTQTELPQLMSAVPASLQGLASPAAASPIDAIPGSGLLAALLNF  240

Query  238  L--------GITFVQNAING----------AVNTTAWFVMATIPNAVFLGHAFAAL----  275
            L        G+    + +NG           V    W  MA I NAV LG   +A     
Sbjct  241  LDGNDGNPYGVFLNSSLVNGFVSAGYVSPAVVGPAIWAAMADI-NAVALGAQESAAVPPM  299

Query  276  -----NPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLTASLGEASSVGGLSVPAGWS  330
                 NP+ + AA+ A P +    G   T   +G GG  ++A + +A  VG +SVP  W 
Sbjct  300  GSGEGNPSWIPAASPASPESLPVLG-EETAATLGTGG--ISAGMNQAELVGRMSVPQSWG  356

Query  331  TAAPAMTSGTTALEGSGW----AVPEEAGPVAAMPGMAGISGAAKGAGAYAGPRYGFKPI  386
             A         A  G GW     VPE A     MPG+ G+     G      PRYGF+P 
Sbjct  357  VATAVANHAGAAAPGGGWTSTAVVPEAA---VGMPGIPGMPAGIYGHNLGNAPRYGFRPT  413

Query  387  VM  388
            +M
Sbjct  414  IM  415


>gi|118618459|ref|YP_906791.1| PPE family protein [Mycobacterium ulcerans Agy99]
 gi|118570569|gb|ABL05320.1| PPE family protein [Mycobacterium ulcerans Agy99]
Length=450

 Score =  222 bits (566),  Expect = 7e-56, Method: Compositional matrix adjust.
 Identities = 167/359 (47%), Positives = 210/359 (59%), Gaps = 34/359 (9%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            MDF ALPPEIN  RMY+G G+AP++AA   W+GLA EL +TA++ E+VI  LT + WLGP
Sbjct  1    MDFAALPPEINPIRMYSGPGSAPMLAAVTAWDGLAAELRSTAAAYETVIAVLTGDGWLGP  60

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS SM  A  PYLAW+  T   A   A QA A+A AFEAAFAMTVPPA+VAANR  L  L
Sbjct  61   ASESMEAAVFPYLAWMNITGMQAEQTARQAAAAAGAFEAAFAMTVPPAQVAANRTQLQTL  120

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATN+LGQNTPAI ATEA YGEMWAQDA AMYGYA  SAAA  L     P+QT + +GLA
Sbjct  121  VATNLLGQNTPAIAATEAAYGEMWAQDAAAMYGYAVGSAAASTLTQFTQPAQTTDPSGLA  180

Query  181  GQAAAVSHAAAAS--TVQQVGLGSLISNLPNAVMGFASP-LTSAADAAGLGGIIQDIEEL  237
             Q+AAV+ A  ++   + Q  L  L+S +P ++ G ASP   S  DA    G++  +   
Sbjct  181  SQSAAVTQAVGSTVGNLTQTELPQLMSAVPASLQGLASPAAASPIDAIPGSGLLAALLNF  240

Query  238  L--------GITFVQNAING----------AVNTTAWFVMATIPNAVFLGHAFAAL----  275
            L        G+    + +NG           V    W  MA I NAV LG   +A     
Sbjct  241  LDGNDGNPYGVFLNSSLVNGFVSAGYVSPAVVGPAIWAAMADI-NAVALGAQESAAVPPM  299

Query  276  -----NPATVTAAADAVPAAAAAAGLAHTVTPVGVGGASLTASLGEASSVGGLSVPAGW  329
                 NP+ + AA+ A P +    G   T   +G GG  ++A + +A  VG +SVP  W
Sbjct  300  GSGEGNPSWIPAASPASPESLPVLG-EETAATLGTGG--ISAGMNQAELVGRMSVPQSW  355


>gi|342862087|ref|ZP_08718730.1| hypothetical protein MCOL_24471 [Mycobacterium colombiense CECT 
3035]
 gi|342130391|gb|EGT83706.1| hypothetical protein MCOL_24471 [Mycobacterium colombiense CECT 
3035]
Length=386

 Score =  220 bits (561),  Expect = 3e-55, Method: Compositional matrix adjust.
 Identities = 194/394 (50%), Positives = 239/394 (61%), Gaps = 10/394 (2%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
             DFGALPPE+NS RMY GAGA P+MAA A ++ LA ELSTTA++ +S I  LT E+W+GP
Sbjct  3    FDFGALPPEVNSLRMYTGAGAGPMMAAAAAFSALADELSTTAAASQSAIANLTGEEWMGP  62

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            +S++M  AAQPY+ W+  TA     AA+QAMASAAA+EAAFAMTVPP  VAANRA LA+L
Sbjct  63   SSVAMATAAQPYVTWMHTTAAQLQQAASQAMASAAAYEAAFAMTVPPPLVAANRAQLASL  122

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATNVLGQNT AI ATEA YGEMWAQDA AMYGYAA+SAAA RL+PL  P+ T    GL 
Sbjct  123  VATNVLGQNTAAIAATEAQYGEMWAQDAAAMYGYAAASAAAARLSPLTDPAPTNGPGGLG  182

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELLGI  240
             Q AA +        Q  GL  ++S++PNAV  FA+P  + A A         ++ +LG 
Sbjct  183  VQTAATA-------AQTSGLRGVVSSVPNAVQSFAAPAAAPAAAPAATTAASALDSVLGD  235

Query  241  TFVQNAINGAVNTTAWFVMATIPNAVFLGHAFAALNPATVTAAADAVPAAAAAAGLAHTV  300
              V N  N   +  +W V  TI + +   H       A V           A  G A   
Sbjct  236  PLVSNIGNAGFDAVSWNVFNTIVSNILYNHTLDTAAAAGVAGDVTGGIGGGALVGAAAPA  295

Query  301  TPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGWAVPEEAGPVAAM  360
                VG A + AS+G AS VGGLS PA WS A P + + T A  G+GW  P E       
Sbjct  296  AAANVGAAPVLASVGSASPVGGLSTPAAWSAATPRVPAATVA--GTGWTAPTEEAHTTWA  353

Query  361  PGMAGISGAAKGAGAYAGPRYGFKPIVMPKQVVV  394
             GM  ++ A +G G   GPRYG KP VMP +++V
Sbjct  354  SGMPAVASAGRG-GYGMGPRYGVKPKVMPTRLLV  386


>gi|342861296|ref|ZP_08717944.1| PPE family protein [Mycobacterium colombiense CECT 3035]
 gi|342131196|gb|EGT84477.1| PPE family protein [Mycobacterium colombiense CECT 3035]
Length=395

 Score =  220 bits (560),  Expect = 4e-55, Method: Compositional matrix adjust.
 Identities = 178/407 (44%), Positives = 237/407 (59%), Gaps = 35/407 (8%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            +DF ALPPEINS RMY+G G+ P++AA A WN +A E+   A+S  SV+ +L++E WLGP
Sbjct  2    LDFAALPPEINSARMYSGPGSGPMLAAAAAWNTMAAEMRAAAASYGSVVTELSSEGWLGP  61

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            +SMSM+ AA PYLAWL  TA  A    +QA A+A A+E+AFAMTVPPA VAANRA LA L
Sbjct  62   SSMSMLAAAAPYLAWLDGTATQAEEVGSQAFAAATAYESAFAMTVPPAVVAANRAQLAML  121

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            VATN+ GQNTPAI ATEA Y EMWAQDA AM GYA +S+AA +  PL TP    N  G+A
Sbjct  122  VATNIFGQNTPAIAATEAQYAEMWAQDAGAMNGYATASSAAAQFTPLATPQSNTNADGVA  181

Query  181  GQAAAVSHAAAASTVQQVGLGSLISNL-----------PNAVMGFASPLTSAADAAGLGG  229
            GQ  AV+       V Q   G++ SNL           P +V  + + L S +D +  G 
Sbjct  182  GQTNAVAQ------VAQTPAGAVQSNLSSAASGSSSSSPGSVSSYLAGLLSGSDNSAFGT  235

Query  230  IIQDIEELLGITFVQNAINGAVNTTAW---FVMATIPNAVFLGHAFAALNPATVTAAADA  286
                     G  F    +NGA+    +   F+++++   +   HA A      +   A  
Sbjct  236  FTN------GNFFSTAVVNGALAGGPFNPQFIISSLQGVLAAQHATAL---GGLGDFAAD  286

Query  287  VPAAAAAAGLAHTVTPVGVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGS  346
                AAA   ++TV   G+GGAS  A +G A  VG +SVP  W++AA  +  G TA++ +
Sbjct  287  ADGVAAADLASNTVGSAGLGGAS--AGVGNAHLVGSMSVPQSWASAA-NINPGQTAVQAT  343

Query  347  GWAVPEEAGPVAAMPGMAGISGAAKGAG---AYAGPRYGFKPIVMPK  390
            G     +AG   A  G  G++G   G G     A P+YGF+P+VMP+
Sbjct  344  GVTGLTDAGAAPAAGGPGGVAGPMGGTGRRLRRAIPKYGFRPVVMPR  390


>gi|240172861|ref|ZP_04751520.1| PPE family protein, PPE31 [Mycobacterium kansasii ATCC 12478]
Length=401

 Score =  216 bits (549),  Expect = 7e-54, Method: Compositional matrix adjust.
 Identities = 183/402 (46%), Positives = 234/402 (59%), Gaps = 22/402 (5%)

Query  1    MDFGALPPEINSTRMYAGAGAAPLMAAGATWNGLAVELSTTASSVESVIMQLTTEQWLGP  60
            +DF  LPPEINS RMY+G G+ P++AA + W  LA EL  TA S  SV+  LT E+W GP
Sbjct  5    LDFAMLPPEINSARMYSGPGSGPMLAAASAWKSLAAELRATALSYHSVLAALTGEEWYGP  64

Query  61   ASMSMVVAAQPYLAWLTYTAESAAHAAAQAMASAAAFEAAFAMTVPPAEVAANRALLAAL  120
            AS SM  AA PY+AWL  TA  A   A QA A+A A+EAAF  TVPP  +AANRA L AL
Sbjct  65   ASASMAAAAAPYVAWLNTTAVQAEQTAVQAEAAAGAYEAAFGATVPPPVIAANRAQLMAL  124

Query  121  VATNVLGQNTPAIMATEAHYGEMWAQDALAMYGYAASSAAAGRLNPLITPSQTANMAGLA  180
            +ATN+LGQNTPAI ATEA Y EMWAQDA+AMYGYA SSAAA +L+P + P Q  N +GLA
Sbjct  125  IATNILGQNTPAIAATEAQYTEMWAQDAMAMYGYAGSSAAATQLSPFVEPQQATNPSGLA  184

Query  181  GQAAAVSHAAAASTVQQVG-LGSLISNLPNAVMGFASPLTSAADAAGLGGIIQDIEELL-  238
             QAAAV+ A+A S   Q   L  LIS +P+A+ G + P +++         +Q I +LL 
Sbjct  185  AQAAAVTEASANSAGNQSSTLSGLISMVPSALQGLSGPNSTS--------WLQVIWDLLT  236

Query  239  --GITFVQNAIN-GAVNTTAWFVMAT----IPNAVFLGHAFAALNPATVTAAADAVPAAA  291
              G  + Q   N    N   W  + +    +P + F     + L  A    AA    AAA
Sbjct  237  GSGPAWWQTLWNVWGPNANVWNTITSTGLFVPGSTFAPFMASVLAGAVAADAAQDASAAA  296

Query  292  AAAGLAHTVTPV---GVGGASLTASLGEASSVGGLSVPAGWSTAAPAMTSGTTALEGSGW  348
            A  G      P+   G  G++++A LG A  VG LSVP  W+ AAP  +   +AL G+  
Sbjct  297  AGVGSGLAAGPLASTGSVGSAVSAGLGNAGIVGKLSVPPAWTAAAPLHSPLGSALGGTPM  356

Query  349  AVPEEAGPVAAMPGMAGISGAAKGAGAYAGPRYGFKPIVMPK  390
              P  A   A MPGM   + A +  G  A P+YGF+P  + +
Sbjct  357  VAPPPAV-AAGMPGMPFGNMAGQPFG-RAVPQYGFRPTFVAR  396



Lambda     K      H
   0.314    0.124    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 770431090464


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40