BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2778c

Length=156
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15609915|ref|NP_217294.1|  hypothetical protein Rv2778c [Mycob...   317    5e-85
gi|339295627|gb|AEJ47738.1|  hypothetical protein CCDC5079_2548 [...   298    2e-79
gi|240171319|ref|ZP_04749978.1|  hypothetical protein MkanA1_1855...   235    2e-60
gi|118617710|ref|YP_906042.1|  hypothetical protein MUL_2156 [Myc...   234    2e-60
gi|296171649|ref|ZP_06852863.1|  conserved hypothetical protein [...   224    3e-57
gi|41408985|ref|NP_961821.1|  hypothetical protein MAP2887c [Myco...   219    8e-56
gi|254819249|ref|ZP_05224250.1|  hypothetical protein MintA_04946...   219    1e-55
gi|118464976|ref|YP_882849.1|  hypothetical protein MAV_3672 [Myc...   218    2e-55
gi|254776107|ref|ZP_05217623.1|  hypothetical protein MaviaA2_157...   209    1e-52
gi|342858351|ref|ZP_08715006.1|  hypothetical protein MCOL_05736 ...   208    3e-52
gi|108802048|ref|YP_642245.1|  hypothetical protein Mmcs_5085 [My...   202    1e-50
gi|126438026|ref|YP_001073717.1|  hypothetical protein Mjls_5463 ...   199    1e-49
gi|271970135|ref|YP_003344331.1|  hypothetical protein Sros_8957 ...   132    2e-29
gi|300791005|ref|YP_003771296.1|  hypothetical protein AMED_9205 ...   114    4e-24
gi|325002254|ref|ZP_08123366.1|  hypothetical protein PseP1_25991...  94.7    4e-18
gi|54024391|ref|YP_118633.1|  hypothetical protein nfa24220 [Noca...  92.8    1e-17
gi|239985809|ref|ZP_04706473.1|  hypothetical protein SrosN1_0073...  85.9    2e-15
gi|182434118|ref|YP_001821837.1|  hypothetical protein SGR_325 [S...  83.6    8e-15
gi|340527528|gb|AEK42733.1|  hypothetical protein RAM_21265 [Amyc...  83.6    9e-15
gi|345003909|ref|YP_004806763.1|  polyketide cyclase/dehydrase [S...  80.9    6e-14
gi|333917854|ref|YP_004491435.1|  Activator of Hsp90 ATPase 1 fam...  80.1    1e-13
gi|300786063|ref|YP_003766354.1|  hypothetical protein AMED_4175 ...  78.6    3e-13
gi|302544826|ref|ZP_07297168.1|  cyclase/dehydrase [Streptomyces ...  77.4    6e-13
gi|320006836|gb|ADW01686.1|  Polyketide cyclase/dehydrase [Strept...  75.9    2e-12
gi|84495029|ref|ZP_00994148.1|  hypothetical protein JNB_09524 [J...  74.7    4e-12
gi|297190029|ref|ZP_06907427.1|  conserved hypothetical protein [...  73.9    7e-12
gi|111020928|ref|YP_703900.1|  hypothetical protein RHA1_ro03945 ...  73.2    1e-11
gi|269128298|ref|YP_003301668.1|  activator of Hsp90 ATPase 1 fam...  72.8    2e-11
gi|254393880|ref|ZP_05008986.1|  conserved hypothetical protein [...  71.6    3e-11
gi|294633375|ref|ZP_06711934.1|  conserved hypothetical protein [...  68.6    3e-10
gi|226363224|ref|YP_002781006.1|  hypothetical protein ROP_38140 ...  68.2    4e-10
gi|291454350|ref|ZP_06593740.1|  predicted protein [Streptomyces ...  67.8    5e-10
gi|291455222|ref|ZP_06594612.1|  conserved hypothetical protein [...  67.0    8e-10
gi|308369548|ref|ZP_07418223.2|  hypothetical protein TMBG_00416 ...  65.9    2e-09
gi|326903486|gb|EGE50419.1|  hypothetical protein TBPG_01361 [Myc...  65.9    2e-09
gi|15841353|ref|NP_336390.1|  hypothetical protein MT1931.1 [Myco...  65.9    2e-09
gi|134096650|ref|YP_001102311.1|  hypothetical protein SACE_0032 ...  63.9    8e-09
gi|15828098|ref|NP_302361.1|  hypothetical protein ML2031 [Mycoba...  63.2    1e-08
gi|118619838|ref|YP_908170.1|  hypothetical protein MUL_4783 [Myc...  62.8    2e-08
gi|315443123|ref|YP_004076002.1|  polyketide cyclase / dehydrase ...  62.4    2e-08
gi|342859532|ref|ZP_08716185.1|  cyclase/dehydrase [Mycobacterium...  62.4    2e-08
gi|226304668|ref|YP_002764626.1|  hypothetical protein RER_11790 ...  61.2    5e-08
gi|120405594|ref|YP_955423.1|  hypothetical protein Mvan_4642 [My...  60.5    8e-08
gi|333990612|ref|YP_004523226.1|  hypothetical protein JDM601_197...  60.1    1e-07
gi|229494359|ref|ZP_04388122.1|  conserved hypothetical protein [...  59.7    1e-07
gi|296164902|ref|ZP_06847458.1|  cyclase/dehydrase [Mycobacterium...  58.9    2e-07
gi|345012246|ref|YP_004814600.1|  polyketide cyclase/dehydrase [S...  58.5    3e-07
gi|296167317|ref|ZP_06849719.1|  cyclase/dehydrase [Mycobacterium...  58.5    3e-07
gi|15609020|ref|NP_216399.1|  hypothetical protein Rv1883c [Mycob...  58.2    4e-07
gi|237785071|ref|YP_002905776.1|  hypothetical protein ckrop_0456...  58.2    4e-07


>gi|15609915|ref|NP_217294.1| hypothetical protein Rv2778c [Mycobacterium tuberculosis H37Rv]
 gi|15842316|ref|NP_337353.1| hypothetical protein MT2848 [Mycobacterium tuberculosis CDC1551]
 gi|31793953|ref|NP_856446.1| hypothetical protein Mb2800c [Mycobacterium bovis AF2122/97]
 78 more sequence titles
 Length=156

 Score =  317 bits (811),  Expect = 5e-85, Method: Compositional matrix adjust.
 Identities = 156/156 (100%), Positives = 156/156 (100%), Gaps = 0/156 (0%)

Query  1    MPDPDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRN  60
            MPDPDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRN
Sbjct  1    MPDPDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRN  60

Query  61   ENGGRRWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSW  120
            ENGGRRWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSW
Sbjct  61   ENGGRRWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSW  120

Query  121  FRAVARMATGVKDRASVNTEHIRRTLQRLKDRAEAG  156
            FRAVARMATGVKDRASVNTEHIRRTLQRLKDRAEAG
Sbjct  121  FRAVARMATGVKDRASVNTEHIRRTLQRLKDRAEAG  156


>gi|339295627|gb|AEJ47738.1| hypothetical protein CCDC5079_2548 [Mycobacterium tuberculosis 
CCDC5079]
 gi|339299244|gb|AEJ51354.1| hypothetical protein CCDC5180_2517 [Mycobacterium tuberculosis 
CCDC5180]
Length=148

 Score =  298 bits (763),  Expect = 2e-79, Method: Compositional matrix adjust.
 Identities = 147/148 (99%), Positives = 148/148 (100%), Gaps = 0/148 (0%)

Query  9    VTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWT  68
            +TVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWT
Sbjct  1    MTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWT  60

Query  69   TTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVARMA  128
            TTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVARMA
Sbjct  61   TTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVARMA  120

Query  129  TGVKDRASVNTEHIRRTLQRLKDRAEAG  156
            TGVKDRASVNTEHIRRTLQRLKDRAEAG
Sbjct  121  TGVKDRASVNTEHIRRTLQRLKDRAEAG  148


>gi|240171319|ref|ZP_04749978.1| hypothetical protein MkanA1_18551 [Mycobacterium kansasii ATCC 
12478]
Length=153

 Score =  235 bits (599),  Expect = 2e-60, Method: Compositional matrix adjust.
 Identities = 111/149 (75%), Positives = 127/149 (86%), Gaps = 0/149 (0%)

Query  7    PSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRR  66
            PSV+ TV+I+A+P  VYGLITDL TLASLAEE V+M+LRKGD +RKGAVFVG NENG RR
Sbjct  4    PSVSATVQINASPQRVYGLITDLSTLASLAEEAVSMELRKGDGIRKGAVFVGHNENGSRR  63

Query  67   WTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVAR  126
            W TTCTVTDA+PGR FAFDVRS +IP++RWQY IVA+  GCRVTESTWDRRP WFR +A 
Sbjct  64   WNTTCTVTDAEPGRTFAFDVRSAVIPVARWQYDIVASGGGCRVTESTWDRRPRWFRKIAG  123

Query  127  MATGVKDRASVNTEHIRRTLQRLKDRAEA  155
            MATGV DRA+ N EHI+ TL+RLK RAEA
Sbjct  124  MATGVGDRAAANAEHIQLTLRRLKQRAEA  152


>gi|118617710|ref|YP_906042.1| hypothetical protein MUL_2156 [Mycobacterium ulcerans Agy99]
 gi|183981943|ref|YP_001850234.1| hypothetical protein MMAR_1930 [Mycobacterium marinum M]
 gi|118569820|gb|ABL04571.1| conserved protein [Mycobacterium ulcerans Agy99]
 gi|183175269|gb|ACC40379.1| conserved protein [Mycobacterium marinum M]
Length=154

 Score =  234 bits (598),  Expect = 2e-60, Method: Compositional matrix adjust.
 Identities = 115/150 (77%), Positives = 124/150 (83%), Gaps = 0/150 (0%)

Query  7    PSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRR  66
            PSV  TVEIDA P+ VYGLITDL TLASLAEE VAM+L+KGD V KGAVFVG N NGGRR
Sbjct  4    PSVAATVEIDATPERVYGLITDLRTLASLAEEAVAMELQKGDGVGKGAVFVGHNRNGGRR  63

Query  67   WTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVAR  126
            W TTCTVTDA+PGR+FAFDV S  IP+SRWQY IV  + GCRVTESTWDRRP WFR VA 
Sbjct  64   WKTTCTVTDAEPGRIFAFDVHSIFIPVSRWQYDIVGADGGCRVTESTWDRRPGWFRKVAG  123

Query  127  MATGVKDRASVNTEHIRRTLQRLKDRAEAG  156
            +ATGVKDRA+ N EHI  TLQRLK RAEAG
Sbjct  124  LATGVKDRAATNAEHIATTLQRLKQRAEAG  153


>gi|296171649|ref|ZP_06852863.1| conserved hypothetical protein [Mycobacterium parascrofulaceum 
ATCC BAA-614]
 gi|295894010|gb|EFG73773.1| conserved hypothetical protein [Mycobacterium parascrofulaceum 
ATCC BAA-614]
Length=153

 Score =  224 bits (571),  Expect = 3e-57, Method: Compositional matrix adjust.
 Identities = 109/149 (74%), Positives = 122/149 (82%), Gaps = 0/149 (0%)

Query  7    PSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRR  66
            PSVT TV++DA PD+VY LITDLPTLASLAEE VAM+ RKGD  R GAVF G NENG  R
Sbjct  4    PSVTATVQVDAGPDVVYRLITDLPTLASLAEEAVAMEWRKGDAARPGAVFTGHNENGKLR  63

Query  67   WTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVAR  126
            W+T CTVTDADPGR FAFDVR  ++PI+RWQY IVA + GCRVTESTWDRRP+WFR +A 
Sbjct  64   WSTKCTVTDADPGRRFAFDVRHTVLPIARWQYDIVAADGGCRVTESTWDRRPAWFRKLAG  123

Query  127  MATGVKDRASVNTEHIRRTLQRLKDRAEA  155
             ATGV DR + NTEHIR TLQRLK RAE+
Sbjct  124  RATGVPDRVAANTEHIRLTLQRLKQRAES  152


>gi|41408985|ref|NP_961821.1| hypothetical protein MAP2887c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|41397344|gb|AAS05204.1| hypothetical protein MAP_2887c [Mycobacterium avium subsp. paratuberculosis 
K-10]
 gi|336458958|gb|EGO37912.1| Polyketide cyclase / dehydrase and lipid transport [Mycobacterium 
avium subsp. paratuberculosis S397]
Length=153

 Score =  219 bits (559),  Expect = 8e-56, Method: Compositional matrix adjust.
 Identities = 107/149 (72%), Positives = 118/149 (80%), Gaps = 0/149 (0%)

Query  7    PSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRR  66
            PSV+ +V IDA P++VY LITDLPTLASLAEE VAMQ RKGD  R GAVF G N+NGGRR
Sbjct  4    PSVSASVHIDARPEVVYRLITDLPTLASLAEEAVAMQWRKGDAARPGAVFTGHNQNGGRR  63

Query  67   WTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVAR  126
            W+T CTVTDA+PGR FAFDVR  + P++RWQY IV T+ GC VTESTWDRRP WF  VA 
Sbjct  64   WSTKCTVTDAEPGRRFAFDVRHTVFPVARWQYDIVGTDGGCDVTESTWDRRPGWFAKVAG  123

Query  127  MATGVKDRASVNTEHIRRTLQRLKDRAEA  155
             ATGV DRA  N EHIR TLQRLK RAEA
Sbjct  124  RATGVTDRAGANAEHIRLTLQRLKQRAEA  152


>gi|254819249|ref|ZP_05224250.1| hypothetical protein MintA_04946 [Mycobacterium intracellulare 
ATCC 13950]
Length=153

 Score =  219 bits (557),  Expect = 1e-55, Method: Compositional matrix adjust.
 Identities = 107/149 (72%), Positives = 118/149 (80%), Gaps = 0/149 (0%)

Query  6    GPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGR  65
             P V+ TV+IDA PD+VY LIT LPTLASLAEE VAMQ RKG+ V  GAVF G NEN GR
Sbjct  3    APCVSATVQIDARPDVVYRLITHLPTLASLAEEAVAMQWRKGEAVAPGAVFAGHNENRGR  62

Query  66   RWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVA  125
            RW+T CTVTDA+PGR FAFDVR  I+P++RWQY IVA + GC VTESTWDRRP WFR VA
Sbjct  63   RWSTRCTVTDAEPGRRFAFDVRYSILPVARWQYDIVAADGGCEVTESTWDRRPGWFRKVA  122

Query  126  RMATGVKDRASVNTEHIRRTLQRLKDRAE  154
              ATGV DR + NTEHIR TLQRLK RAE
Sbjct  123  GKATGVSDRVAANTEHIRLTLQRLKQRAE  151


>gi|118464976|ref|YP_882849.1| hypothetical protein MAV_3672 [Mycobacterium avium 104]
 gi|118166263|gb|ABK67160.1| conserved hypothetical protein [Mycobacterium avium 104]
Length=153

 Score =  218 bits (555),  Expect = 2e-55, Method: Compositional matrix adjust.
 Identities = 107/149 (72%), Positives = 117/149 (79%), Gaps = 0/149 (0%)

Query  7    PSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRR  66
            PSV+ +V IDA P++VY LITDLPTLASLAEE VAMQ RKGD  R GAVF G N NGGRR
Sbjct  4    PSVSASVHIDARPEVVYRLITDLPTLASLAEEAVAMQWRKGDAARPGAVFTGHNRNGGRR  63

Query  67   WTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVAR  126
            W+T CTVTDA+PGR FAFDVR  + P++RWQY IV T+ GC VTESTWDRRP WF  VA 
Sbjct  64   WSTKCTVTDAEPGRRFAFDVRHTVFPVARWQYDIVGTDGGCDVTESTWDRRPGWFAKVAG  123

Query  127  MATGVKDRASVNTEHIRRTLQRLKDRAEA  155
             ATGV DRA  N EHIR TLQRLK RAEA
Sbjct  124  RATGVTDRAGANAEHIRLTLQRLKQRAEA  152


>gi|254776107|ref|ZP_05217623.1| hypothetical protein MaviaA2_15745 [Mycobacterium avium subsp. 
avium ATCC 25291]
Length=144

 Score =  209 bits (532),  Expect = 1e-52, Method: Compositional matrix adjust.
 Identities = 102/143 (72%), Positives = 113/143 (80%), Gaps = 0/143 (0%)

Query  13   VEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWTTTCT  72
            + IDA P++VY LITDLPTLASLAEE VAM+ RKGD  R GAVF G N+NGGRRW+T CT
Sbjct  1    MHIDARPEVVYRLITDLPTLASLAEEAVAMEWRKGDAARPGAVFTGHNQNGGRRWSTKCT  60

Query  73   VTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVARMATGVK  132
            VTDA+PGR FAFDVR  + P++RWQY IV T+ GC VTESTWDRRP WF  VA  ATGV 
Sbjct  61   VTDAEPGRRFAFDVRHTVFPVARWQYDIVGTDGGCDVTESTWDRRPGWFAKVAGRATGVT  120

Query  133  DRASVNTEHIRRTLQRLKDRAEA  155
            DRA  N EHIR TLQRLK RAEA
Sbjct  121  DRAGANAEHIRLTLQRLKQRAEA  143


>gi|342858351|ref|ZP_08715006.1| hypothetical protein MCOL_05736 [Mycobacterium colombiense CECT 
3035]
 gi|342134055|gb|EGT87235.1| hypothetical protein MCOL_05736 [Mycobacterium colombiense CECT 
3035]
Length=153

 Score =  208 bits (529),  Expect = 3e-52, Method: Compositional matrix adjust.
 Identities = 102/148 (69%), Positives = 112/148 (76%), Gaps = 0/148 (0%)

Query  7    PSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRR  66
            P    TV+IDA PD+VY LITDLPTLA LAEE VAM+ RKGD V  GAVF G N +G RR
Sbjct  4    PCAQATVQIDARPDVVYRLITDLPTLAELAEEAVAMEWRKGDAVSPGAVFTGHNRSGSRR  63

Query  67   WTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVAR  126
            W+T CT+TDA+PGR FAFDV   +IPI+RWQY I A   GC VTESTWDRRP WFR VA 
Sbjct  64   WSTKCTITDAEPGRRFAFDVSHTMIPIARWQYDIAAAGGGCEVTESTWDRRPGWFRKVAG  123

Query  127  MATGVKDRASVNTEHIRRTLQRLKDRAE  154
             ATGV DR + NTEHIR TLQRLK RAE
Sbjct  124  KATGVSDRVTANTEHIRLTLQRLKRRAE  151


>gi|108802048|ref|YP_642245.1| hypothetical protein Mmcs_5085 [Mycobacterium sp. MCS]
 gi|119871200|ref|YP_941152.1| hypothetical protein Mkms_5173 [Mycobacterium sp. KMS]
 gi|108772467|gb|ABG11189.1| hypothetical protein Mmcs_5085 [Mycobacterium sp. MCS]
 gi|119697289|gb|ABL94362.1| conserved hypothetical protein [Mycobacterium sp. KMS]
Length=155

 Score =  202 bits (515),  Expect = 1e-50, Method: Compositional matrix adjust.
 Identities = 101/155 (66%), Positives = 115/155 (75%), Gaps = 0/155 (0%)

Query  1    MPDPDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRN  60
            M +PD  S   TV+IDA+P  VY LITDL TLA LAEE  AM+ +KGD  R GAVFVGRN
Sbjct  1    MTNPDAASAKATVDIDADPATVYRLITDLRTLAELAEETSAMEWKKGDAARPGAVFVGRN  60

Query  61   ENGGRRWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSW  120
             NG R W+TTCTVTDA PG+VFAFDVRS +IP++ W+Y I  T  GCRVTESTWDRRP W
Sbjct  61   RNGSRSWSTTCTVTDATPGQVFAFDVRSTVIPVAHWRYEISPTASGCRVTESTWDRRPGW  120

Query  121  FRAVARMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
            FR  A  ATGV DR + N E+I  TL+RLK RAEA
Sbjct  121  FRKPAGWATGVSDRDTANAENIAATLRRLKARAEA  155


>gi|126438026|ref|YP_001073717.1| hypothetical protein Mjls_5463 [Mycobacterium sp. JLS]
 gi|126237826|gb|ABO01227.1| conserved hypothetical protein [Mycobacterium sp. JLS]
Length=155

 Score =  199 bits (507),  Expect = 1e-49, Method: Compositional matrix adjust.
 Identities = 100/155 (65%), Positives = 114/155 (74%), Gaps = 0/155 (0%)

Query  1    MPDPDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRN  60
            M +P   S   TV+IDA+P  VY LITDL TLA LAEE  AM+ +KGDD R GAVFVGRN
Sbjct  1    MTNPAAASAKATVDIDADPATVYRLITDLRTLAELAEETSAMEWKKGDDARPGAVFVGRN  60

Query  61   ENGGRRWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSW  120
             NG R W+TTCTVTDA PG+VFAFDVRS +IP++ W+Y I  T  GCRVTESTWDRRP W
Sbjct  61   RNGSRSWSTTCTVTDATPGQVFAFDVRSTVIPVAHWRYEISPTASGCRVTESTWDRRPGW  120

Query  121  FRAVARMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
            FR  A  ATGV DR + N  +I  TL+RLK RAEA
Sbjct  121  FRKPAGWATGVSDRDTANAGNIAATLRRLKARAEA  155


>gi|271970135|ref|YP_003344331.1| hypothetical protein Sros_8957 [Streptosporangium roseum DSM 
43021]
 gi|270513310|gb|ACZ91588.1| hypothetical protein Sros_8957 [Streptosporangium roseum DSM 
43021]
Length=156

 Score =  132 bits (331),  Expect = 2e-29, Method: Compositional matrix adjust.
 Identities = 74/155 (48%), Positives = 100/155 (65%), Gaps = 12/155 (7%)

Query  7    PSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGD------DVRKGAVFVGRN  60
            PS +V+V + A P +VYGL+TD+   A + E  V  + R+ D      + R GA F GRN
Sbjct  4    PSASVSVHVSAPPAVVYGLVTDI---ADMGEWNV--ECRRADWVGRVREARPGARFRGRN  58

Query  61   ENGGRRWTTTCTVTDADPGRVFAFDVRS-GIIPISRWQYGIVATEHGCRVTESTWDRRPS  119
             NG R W+T CTVT ADPGRVFA+ VR+ G++ ++ W++GI  TE GC V +STWD R  
Sbjct  59   SNGWRHWSTLCTVTAADPGRVFAYHVRAAGLLDVALWRFGITPTEAGCHVEQSTWDTRGP  118

Query  120  WFRAVARMATGVKDRASVNTEHIRRTLQRLKDRAE  154
              R V  + TGV+DRA+ N  ++RRTL+ LK  AE
Sbjct  119  LMRVVGGLVTGVRDRAAHNEANMRRTLEGLKRVAE  153


>gi|300791005|ref|YP_003771296.1| hypothetical protein AMED_9205 [Amycolatopsis mediterranei U32]
 gi|299800519|gb|ADJ50894.1| conserved hypothetical protein [Amycolatopsis mediterranei U32]
 gi|340532702|gb|AEK47907.1| hypothetical protein RAM_47210 [Amycolatopsis mediterranei S699]
Length=160

 Score =  114 bits (286),  Expect = 4e-24, Method: Compositional matrix adjust.
 Identities = 72/153 (48%), Positives = 90/153 (59%), Gaps = 2/153 (1%)

Query  5    DGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGD-DVRKGAVFVGRNENG  63
            + P+ T  +EIDA P+ VY L++D   LA LAEE    +   G  +   GA F GRN  G
Sbjct  6    NAPNATGRIEIDAAPEAVYSLVSDPGQLAGLAEEYAGHRWVGGACEPAVGAKFRGRNRRG  65

Query  64   GRRWTTTCTVTDADPGRVFAFDVRS-GIIPISRWQYGIVATEHGCRVTESTWDRRPSWFR  122
             RRW+T  T+TDA+PGR F F+V S   +P++RWQY       GC V ES W+RRP+WF 
Sbjct  66   FRRWSTLSTITDAEPGRRFGFEVTSVAGLPVARWQYDFEPARDGCVVVESMWERRPAWFE  125

Query  123  AVARMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
                  TGV DR   NT +I  TL RLK  AEA
Sbjct  126  VATSTVTGVWDREQANTANIAATLARLKRAAEA  158


>gi|325002254|ref|ZP_08123366.1| hypothetical protein PseP1_25991 [Pseudonocardia sp. P1]
Length=155

 Score = 94.7 bits (234),  Expect = 4e-18, Method: Compositional matrix adjust.
 Identities = 59/139 (43%), Positives = 77/139 (56%), Gaps = 5/139 (3%)

Query  19   PDLVYGLITDLPTLASLAEEVVA---MQLRKGDDVRKGAVFVGRNENGGRRWTTTCTVTD  75
            P+ VY L++DLP +   + E      +    G  V  GA F G N  G RRW TT  VTD
Sbjct  16   PETVYHLVSDLPRMGEWSPENTGGRWVGTPTGPVV--GARFAGTNRRGLRRWPTTTVVTD  73

Query  76   ADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVARMATGVKDRA  135
            A PGR FAF+ R G +  + W Y I  T  GC VTES  D R +   A+ R+ TGV+DRA
Sbjct  74   ATPGRRFAFETRLGPVTAAEWIYEITPTGTGCEVTESWVDLRRAPVVAIGRVVTGVRDRA  133

Query  136  SVNTEHIRRTLQRLKDRAE  154
            +   + +  TL++LK  AE
Sbjct  134  AFTRDMLTTTLEKLKATAE  152


>gi|54024391|ref|YP_118633.1| hypothetical protein nfa24220 [Nocardia farcinica IFM 10152]
 gi|54015899|dbj|BAD57269.1| hypothetical protein [Nocardia farcinica IFM 10152]
Length=170

 Score = 92.8 bits (229),  Expect = 1e-17, Method: Compositional matrix adjust.
 Identities = 63/164 (39%), Positives = 84/164 (52%), Gaps = 12/164 (7%)

Query  4    PDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLR-KGDDVRKGAVFVGRNEN  62
            P    VT +V +  +P   Y  I+D+  +   + E     LR  G  VR G  FVG N  
Sbjct  2    PRSREVTDSVVVAVDPQTAYARISDVTQMGRWSPENTGAALRDPGAPVRVGTRFVGSNVR  61

Query  63   GGRRWTTTCTVTDADPGRVFA-----FDVRSGIIP--ISRWQYGIVATEHGCRVTESTWD  115
             G RW T C VT A+PGR+FA     F VR  ++P  I+ W+Y     E G R+TE+ +D
Sbjct  62   RGFRWHTECVVTAAEPGRLFAFAVRKFGVRKPVLPVAIASWEYRFEPVEGGSRITETWYD  121

Query  116  RRPSWFRAVA----RMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
             R +W  A+     R+ATG    A     +IRRTL+RLK   EA
Sbjct  122  DRAAWPDALTAVFDRLATGTPGFAVYQRGNIRRTLERLKTELEA  165


>gi|239985809|ref|ZP_04706473.1| hypothetical protein SrosN1_00730 [Streptomyces roseosporus NRRL 
11379]
 gi|239992589|ref|ZP_04713253.1| hypothetical protein SrosN1_35173 [Streptomyces roseosporus NRRL 
11379]
 gi|291449566|ref|ZP_06588956.1| conserved hypothetical protein [Streptomyces roseosporus NRRL 
15998]
 gi|291352513|gb|EFE79417.1| conserved hypothetical protein [Streptomyces roseosporus NRRL 
15998]
Length=172

 Score = 85.9 bits (211),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 65/161 (41%), Positives = 84/161 (53%), Gaps = 14/161 (8%)

Query  8    SVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGD--DVRKGAVFVGRNENGGR  65
            SV  ++ +DA P LVY  ++D   +   + E     +R GD  D   G VF GRN+ G  
Sbjct  6    SVADSIIVDAAPALVYAQLSDPTAMGRWSPENRGATVR-GDRRDAYVGMVFEGRNKRGPA  64

Query  66   RWTTTCTVTDADPGRVFAFDVRSGII-------PISRWQYGIVATEHGCRVTESTWDRRP  118
            RWTT CTVT ADPG  FAF V +  +       PI+ W+Y     +   RVTE+  D R 
Sbjct  65   RWTTRCTVTAADPGERFAFRVHAIGLRRPLLPGPIATWEYRFEVVDGATRVTETWTDDRR  124

Query  119  SW--FRAVA--RMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
             W  F A A  R+ATG K  A     +IR TL+RLK   E+
Sbjct  125  RWPDFLANAFDRVATGGKTFAQFQAGNIRTTLKRLKAALES  165


>gi|182434118|ref|YP_001821837.1| hypothetical protein SGR_325 [Streptomyces griseus subsp. griseus 
NBRC 13350]
 gi|326774642|ref|ZP_08233907.1| Polyketide cyclase/dehydrase [Streptomyces cf. griseus XylebKG-1]
 gi|178462634|dbj|BAG17154.1| conserved hypothetical protein [Streptomyces griseus subsp. griseus 
NBRC 13350]
 gi|326654975|gb|EGE39821.1| Polyketide cyclase/dehydrase [Streptomyces griseus XylebKG-1]
Length=172

 Score = 83.6 bits (205),  Expect = 8e-15, Method: Compositional matrix adjust.
 Identities = 65/164 (40%), Positives = 83/164 (51%), Gaps = 12/164 (7%)

Query  4    PDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLR-KGDDVRKGAVFVGRNEN  62
            P   SV  ++ IDA+P  VY  ++D   +   + E     +R +      G VF GRN+ 
Sbjct  2    PRTMSVADSIVIDASPAQVYEQLSDPTAMGRWSPENRGATVRGEQRAAYVGMVFEGRNKR  61

Query  63   GGRRWTTTCTVTDADPGRVFAFDVRSGII-------PISRWQYGIVATEHGCRVTESTWD  115
            G  RWTT CTVT ADPG  FAF V +  +       PI+ W Y   A +   RVTE+  D
Sbjct  62   GAARWTTRCTVTAADPGERFAFRVHAIGLRRPLLPGPIATWDYRFEAVDGATRVTETWTD  121

Query  116  RRPSW--FRAVA--RMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
             R  W  F A A  R+ATG K  A     +IR TL+RLK   EA
Sbjct  122  DRRRWPDFLANAFDRVATGGKTFAQFQGGNIRTTLKRLKAALEA  165


>gi|340527528|gb|AEK42733.1| hypothetical protein RAM_21265 [Amycolatopsis mediterranei S699]
Length=157

 Score = 83.6 bits (205),  Expect = 9e-15, Method: Compositional matrix adjust.
 Identities = 54/147 (37%), Positives = 75/147 (52%), Gaps = 4/147 (2%)

Query  7    PSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRR  66
            P+++ +V + A+P  V+  +TDLP +  L+ E V  +   G     GA F GRN NG  +
Sbjct  3    PTISRSVTVSADPGTVWSWVTDLPRMGELSPENVGGRWLDGTGPALGARFRGRNRNGELQ  62

Query  67   WTTTCTVTDADPGRVFAFDVRSGIIP-ISRWQYGIVATEHGCRVTESTWDRRPSWF--RA  123
            W T   V   +P R FAFDVR+     +SRW+Y +     GC VTE+ W R  SW   + 
Sbjct  63   WWTRVRVVVFEPDRRFAFDVRTPFGSRVSRWEYVLAPAAGGCVVTEN-WYRIGSWVVRKF  121

Query  124  VARMATGVKDRASVNTEHIRRTLQRLK  150
            +    TG  DR   N   I  TL  L+
Sbjct  122  MGPRVTGRADRPGYNVRSIEHTLAALQ  148


>gi|345003909|ref|YP_004806763.1| polyketide cyclase/dehydrase [Streptomyces sp. SirexAA-E]
 gi|344319535|gb|AEN14223.1| Polyketide cyclase/dehydrase [Streptomyces sp. SirexAA-E]
Length=176

 Score = 80.9 bits (198),  Expect = 6e-14, Method: Compositional matrix adjust.
 Identities = 62/168 (37%), Positives = 87/168 (52%), Gaps = 15/168 (8%)

Query  4    PDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGD-DVRKGAVFVGRNEN  62
            P   SV+ ++ IDA P +VY  ++D   +   + E    ++  G  +   G VF GRN+ 
Sbjct  2    PRTMSVSDSILIDAAPSVVYEHVSDPTAMGRWSPENQGARVLGGQRETHVGMVFEGRNKR  61

Query  63   GGRRWTTTCTVTDADPGRVFAFDVRS--GIIP-----ISRWQYGIVATEHGCRVTESTWD  115
            G  RWTT CTVT ADPG  FAF V +     P     I++W+Y     + G RVTE+  D
Sbjct  62   GAFRWTTRCTVTAADPGVRFAFRVHAIGARQPRLRGAIAQWEYRFEEADGGTRVTETWTD  121

Query  116  RRPSW----FRAVARMATGVKDRASVNTEHIRRTLQRLK---DRAEAG  156
             R +W      A  R+AT  +  A     +IR TL+RLK   + AE+G
Sbjct  122  DRRTWPDVLANAFDRVATRGRTFAEFQRGNIRTTLERLKAALEEAESG  169


>gi|333917854|ref|YP_004491435.1| Activator of Hsp90 ATPase 1 family protein [Amycolicicoccus subflavus 
DQS3-9A1]
 gi|333480075|gb|AEF38635.1| Activator of Hsp90 ATPase 1 family protein [Amycolicicoccus subflavus 
DQS3-9A1]
Length=166

 Score = 80.1 bits (196),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 54/159 (34%), Positives = 80/159 (51%), Gaps = 12/159 (7%)

Query  8    SVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRW  67
            +V+ +++I A P+ +Y LI+D     + + E    ++        G VF G N  G  RW
Sbjct  6    TVSESIDISAPPEQIYALISDPTQTGNWSPENTGARVTSAPH-SAGMVFHGTNRRGPFRW  64

Query  68   TTTCTVTDADPGRVFAFDVRS-GI------IPISRWQYGIVATEHGCRVTESTWDRRPSW  120
             T C VT AD    F F VR  G+      +P++ W+Y +  T HG RVTE+  D R +W
Sbjct  65   VTECVVTGADAPTRFRFQVRKWGVGKPFLTVPVATWEYQLAPTPHGTRVTETWIDDRSAW  124

Query  121  FRAVA----RMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
              +V+    R+ TG +  A  N  +I  TL+ LK   EA
Sbjct  125  PDSVSAVVDRLLTGGRTFAEFNRRNIAVTLKNLKAAVEA  163


>gi|300786063|ref|YP_003766354.1| hypothetical protein AMED_4175 [Amycolatopsis mediterranei U32]
 gi|299795577|gb|ADJ45952.1| conserved hypothetical protein [Amycolatopsis mediterranei U32]
Length=149

 Score = 78.6 bits (192),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 52/139 (38%), Positives = 69/139 (50%), Gaps = 4/139 (2%)

Query  15   IDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWTTTCTVT  74
            + A+P  V+  +TDLP +  L+ E V  +   G     GA F GRN NG  +W T   V 
Sbjct  3    VSADPGTVWSWVTDLPRMGELSPENVGGRWLDGTGPALGARFRGRNRNGELQWWTRVRVV  62

Query  75   DADPGRVFAFDVRSGIIP-ISRWQYGIVATEHGCRVTESTWDRRPSWF--RAVARMATGV  131
              +P R FAFDVR+     +SRW+Y +     GC VTE+ W R  SW   + +    TG 
Sbjct  63   VFEPDRRFAFDVRTPFGSRVSRWEYVLAPAAGGCVVTEN-WYRIGSWVVRKFMGPRVTGR  121

Query  132  KDRASVNTEHIRRTLQRLK  150
             DR   N   I  TL  L+
Sbjct  122  ADRPGYNVRSIEHTLAALQ  140


>gi|302544826|ref|ZP_07297168.1| cyclase/dehydrase [Streptomyces hygroscopicus ATCC 53653]
 gi|302462444|gb|EFL25537.1| cyclase/dehydrase [Streptomyces himastatinicus ATCC 53653]
Length=120

 Score = 77.4 bits (189),  Expect = 6e-13, Method: Compositional matrix adjust.
 Identities = 40/118 (34%), Positives = 65/118 (56%), Gaps = 0/118 (0%)

Query  15   IDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWTTTCTVT  74
            + A+P  VY LI D+  +   + E    +   G+    G+ F G N     +W+T CTVT
Sbjct  1    MAADPQDVYELIADVTRIGEWSPEATGAEWLNGEPGAVGSTFRGHNRRPWVKWSTICTVT  60

Query  75   DADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVARMATGVK  132
             A PG+ FAFDV++   P++ W+  IV  + GC VT+ T+D+R   ++  + + T V+
Sbjct  61   AAGPGKRFAFDVKAAGRPVAAWELEIVPRDGGCEVTQRTFDQRSLLYKVTSVVTTEVR  118


>gi|320006836|gb|ADW01686.1| Polyketide cyclase/dehydrase [Streptomyces flavogriseus ATCC 
33331]
Length=182

 Score = 75.9 bits (185),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 62/164 (38%), Positives = 81/164 (50%), Gaps = 12/164 (7%)

Query  4    PDGPSVTVTVEIDANPDLVYGLITDLPTLASLA-EEVVAMQLRKGDDVRKGAVFVGRNEN  62
            P   SV+ ++ I   P  VY  ++D   +   + E   A  L +      G VF GRN+ 
Sbjct  2    PRTMSVSDSILIRMAPSAVYRELSDPTAMGRWSPENRGARVLGEHRGAHVGMVFEGRNKR  61

Query  63   GGRRWTTTCTVTDADPGRVFAFDV-----RSGIIP--ISRWQYGIVATEHGCRVTESTWD  115
            G  RWTT CTVT ADPG  FAF V     R  ++P  I+ W+Y   + +   RVTE+  D
Sbjct  62   GSFRWTTKCTVTAADPGERFAFRVHAIGARRPLLPGAIALWEYRFESVDGFTRVTETWTD  121

Query  116  RRPSWFRAVA----RMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
             R SW   VA    R+AT     A     +IR TL+RLK   EA
Sbjct  122  NRRSWPDFVANAFDRVATRGHTFAEFQRRNIRTTLERLKAVLEA  165


>gi|84495029|ref|ZP_00994148.1| hypothetical protein JNB_09524 [Janibacter sp. HTCC2649]
 gi|84384522|gb|EAQ00402.1| hypothetical protein JNB_09524 [Janibacter sp. HTCC2649]
Length=170

 Score = 74.7 bits (182),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 52/146 (36%), Positives = 73/146 (50%), Gaps = 13/146 (8%)

Query  19   PDLVYGLITDLPTLASLAEEVVAMQLRKGD--DVRKGAVFVGRNENGGRRWTTTCTVTDA  76
            P  VY  ++D   +A  + E    ++ +G    +  G VFVG N+ GG RW T C V  A
Sbjct  18   PAEVYAQVSDPSQMARWSPENTGAEVERGSLGSLTAGDVFVGANKRGGARWQTRCKVVAA  77

Query  77   DPGRVFAFDV-----RSGI--IPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVARMA-  128
            +PG  F FDV     +S +  I I+RW+Y   AT  G +VTE+  D R  W   VA    
Sbjct  78   EPGERFMFDVVGWGLKSPLLRIAIARWEYTFEATTDGTKVTETWSDARRHWPDVVANAVD  137

Query  129  ---TGVKDRASVNTEHIRRTLQRLKD  151
               TG +  AS    +I +TL  L++
Sbjct  138  SRLTGGRTFASFQKRNIAKTLAALRE  163


>gi|297190029|ref|ZP_06907427.1| conserved hypothetical protein [Streptomyces pristinaespiralis 
ATCC 25486]
 gi|297150345|gb|EFH30575.1| conserved hypothetical protein [Streptomyces pristinaespiralis 
ATCC 25486]
Length=169

 Score = 73.9 bits (180),  Expect = 7e-12, Method: Compositional matrix adjust.
 Identities = 59/161 (37%), Positives = 81/161 (51%), Gaps = 13/161 (8%)

Query  8    SVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKG-DDVRKGAVFVGRNENGGRR  66
            SV+ +V I A P ++Y  +++   +   + E     +R G +    G VF GRN  G   
Sbjct  6    SVSDSVVIGAAPSVIYAHVSNPALMGRWSPENRGATVRSGGEQAYVGMVFDGRNTRGPVS  65

Query  67   WTTTCTVTDADPGRVFAFDVRS-----GIIP--ISRWQYGIV-ATEHGCRVTESTWDRRP  118
            WTT CTVT ADPG  FAF VR+      ++P  I+ W+Y    A   G RVTE+  D R 
Sbjct  66   WTTRCTVTAADPGERFAFRVRAIGRRRPVLPGRIATWEYRFERAAGGGTRVTETWIDDRR  125

Query  119  SWFRAVA----RMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
            +W   VA    ++AT     A     +IR TL+ LK   EA
Sbjct  126  AWPDVVANTFDKLATRGHTFAEFQRRNIRTTLENLKKAMEA  166


>gi|111020928|ref|YP_703900.1| hypothetical protein RHA1_ro03945 [Rhodococcus jostii RHA1]
 gi|110820458|gb|ABG95742.1| conserved hypothetical protein [Rhodococcus jostii RHA1]
Length=154

 Score = 73.2 bits (178),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 44/148 (30%), Positives = 73/148 (50%), Gaps = 5/148 (3%)

Query  10   TVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWTT  69
            + ++ ID  P  V+ ++TD+  +   + E    + + G     GA F+G N +G  RW T
Sbjct  10   SASILIDVPPGKVWNVVTDVEGMGRFSPENTGARWKSGTPAMVGARFIGANRHGPVRWKT  69

Query  70   TCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTES--TWDRRPSWFRAVARM  127
             CTV D  PGR F+F+      P +RW Y +  +  G  VTE+   +     W R V + 
Sbjct  70   HCTVVDVIPGRKFSFEADE---PKARWTYHLEPSGAGTLVTETREIYATPVWWVRLVQKS  126

Query  128  ATGVKDRASVNTEHIRRTLQRLKDRAEA  155
                 +R  +  + +R+TL+R+K   E+
Sbjct  127  KVLGSNRDQLMQDGMRQTLERMKVALES  154


>gi|269128298|ref|YP_003301668.1| activator of Hsp90 ATPase 1 family protein [Thermomonospora curvata 
DSM 43183]
 gi|268313256|gb|ACY99630.1| Activator of Hsp90 ATPase 1 family protein [Thermomonospora curvata 
DSM 43183]
Length=165

 Score = 72.8 bits (177),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 52/151 (35%), Positives = 75/151 (50%), Gaps = 9/151 (5%)

Query  12   TVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWTTTC  71
            ++ I+A P  VY  + +L  +   + E  A+  R+G    +G  FVG N  G R W TT 
Sbjct  14   SIRIEAEPARVYAAVAELRRMGRWSPECFAVWTRRGL-AEEGTRFVGFNRIGWRVWFTTG  72

Query  72   TVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWD------RRPSWFRAVA  125
             VT A PG+VFAF V S  IP++ W Y +     G       W+      R  +    + 
Sbjct  73   RVTAAVPGQVFAFRVSSFGIPVALWGYRLEDVGGGATRLTEYWEDLRRNHRGAALVSLLG  132

Query  126  RMATGVK--DRASVNTEHIRRTLQRLKDRAE  154
            R+ TGV   DRA++N   +R TL+R+K   E
Sbjct  133  RIFTGVAAGDRAALNRRGMRTTLERIKAACE  163


>gi|254393880|ref|ZP_05008986.1| conserved hypothetical protein [Streptomyces clavuligerus ATCC 
27064]
 gi|294816519|ref|ZP_06775162.1| Activator of Hsp90 ATPase 1-like protein [Streptomyces clavuligerus 
ATCC 27064]
 gi|326444839|ref|ZP_08219573.1| hypothetical protein SclaA2_27406 [Streptomyces clavuligerus 
ATCC 27064]
 gi|197707473|gb|EDY53285.1| conserved hypothetical protein [Streptomyces clavuligerus ATCC 
27064]
 gi|294329118|gb|EFG10761.1| Activator of Hsp90 ATPase 1-like protein [Streptomyces clavuligerus 
ATCC 27064]
Length=170

 Score = 71.6 bits (174),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 56/165 (34%), Positives = 82/165 (50%), Gaps = 12/165 (7%)

Query  4    PDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLR-KGDDVRKGAVFVGRNEN  62
            P   +V+ ++ I A P  +Y  +++   +   + E +   +R +  D   G  F G N+ 
Sbjct  2    PRTLAVSDSIVIHAAPAAIYAQVSNPALMGRWSPENLGATVRGEAQDAYVGMEFDGHNQR  61

Query  63   GGRRWTTTCTVTDADPGRVFAFDV-----RSGII--PISRWQYGIVATEHGCRVTESTWD  115
            G  RWTT CTVT A PG+ FAF V     R  ++   I+ W+Y     + G RVTE+  D
Sbjct  62   GQLRWTTRCTVTAAVPGQRFAFRVHAIGRRRPVLRGRIATWEYRFDPVDGGTRVTETWRD  121

Query  116  RRPSWFRAVA----RMATGVKDRASVNTEHIRRTLQRLKDRAEAG  156
             R SW  A+A    R+AT     A     +IRRTL+ LK   E+ 
Sbjct  122  DRRSWPDALANAFDRLATRGHTFAEYQRGNIRRTLRNLKAAMESA  166


>gi|294633375|ref|ZP_06711934.1| conserved hypothetical protein [Streptomyces sp. e14]
 gi|292831156|gb|EFF89506.1| conserved hypothetical protein [Streptomyces sp. e14]
Length=168

 Score = 68.6 bits (166),  Expect = 3e-10, Method: Compositional matrix adjust.
 Identities = 47/113 (42%), Positives = 59/113 (53%), Gaps = 11/113 (9%)

Query  53   GAVFVGRNENGGRRWTTTCTVTDADPGRVFAFDVRSGII-------PISRWQYGIVATEH  105
            G  FVGRN+ G  RW+T CTVT A+PGR FAF V +  +       PI+ W+Y       
Sbjct  52   GDSFVGRNKRGAFRWSTRCTVTAAEPGRRFAFRVHAIGLKRPRLRGPIATWEYTFAPEGA  111

Query  106  GCRVTESTWDRRPSWFRAVA----RMATGVKDRASVNTEHIRRTLQRLKDRAE  154
            G RVTE+  D R +W  AVA    R+ T  K  A     +I  TL+ LK   E
Sbjct  112  GTRVTETWTDDRRAWPDAVAGVFDRIVTSGKTFAEFQNRNIDITLRNLKRELE  164


>gi|226363224|ref|YP_002781006.1| hypothetical protein ROP_38140 [Rhodococcus opacus B4]
 gi|226241713|dbj|BAH52061.1| hypothetical protein [Rhodococcus opacus B4]
Length=147

 Score = 68.2 bits (165),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 44/148 (30%), Positives = 72/148 (49%), Gaps = 5/148 (3%)

Query  10   TVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWTT  69
            + ++ ID     V+G++TD+  +   + E    +   G     GA FVG N +G  RW T
Sbjct  3    SASILIDVPATEVWGVVTDVEGMGRFSPENTGARWTSGTPATVGARFVGANRHGPVRWKT  62

Query  70   TCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTES--TWDRRPSWFRAVARM  127
             CTV D  PG+ F+F+      P +RW Y +  +  G  VTE+   +     W R V + 
Sbjct  63   HCTVVDVVPGQTFSFEADE---PKARWTYRLEPSGSGTLVTETREIYATPVWWVRLVQKS  119

Query  128  ATGVKDRASVNTEHIRRTLQRLKDRAEA  155
                 +R  +  + +R+TL+R+K   E+
Sbjct  120  KVLGSNRDRLMQDGMRQTLERMKVALES  147


>gi|291454350|ref|ZP_06593740.1| predicted protein [Streptomyces albus J1074]
 gi|291357299|gb|EFE84201.1| predicted protein [Streptomyces albus J1074]
Length=160

 Score = 67.8 bits (164),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 50/150 (34%), Positives = 72/150 (48%), Gaps = 4/150 (2%)

Query  9    VTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNEN-GGRRW  67
            V+V   I+A P  VY  + D+ ++   + E V      G     GA F G N+   GR W
Sbjct  7    VSVAAVIEAEPKAVYERVADVASMGRWSPECVRTAAGVGP-APVGAEFKGTNKGPSGRSW  65

Query  68   TTTCTVTDADPGRVFAFDVRSGIIPISRWQYGI--VATEHGCRVTESTWDRRPSWFRAVA  125
            +T C V  A  G  F F VR   +P++ W Y    V       VTE+  D+R      + 
Sbjct  66   STRCRVMVARSGERFTFRVRFWGMPVATWDYRFRPVGDGTATEVTETAVDQRNRLLWFLG  125

Query  126  RMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
               +GV DR++ N E +R TL+RL++  EA
Sbjct  126  SAVSGVWDRSAHNAETMRETLERLRETLEA  155


>gi|291455222|ref|ZP_06594612.1| conserved hypothetical protein [Streptomyces albus J1074]
 gi|291358171|gb|EFE85073.1| conserved hypothetical protein [Streptomyces albus J1074]
Length=171

 Score = 67.0 bits (162),  Expect = 8e-10, Method: Compositional matrix adjust.
 Identities = 55/160 (35%), Positives = 73/160 (46%), Gaps = 13/160 (8%)

Query  8    SVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDV-RKGAVFVGRNENGGRR  66
            +V+ +V +   P   Y LI D   +   + E     +R  D     G VF GRN  G  R
Sbjct  2    TVSGSVVVPIAPRQAYALIADPAGMGRWSPENEGAVVRGEDGAPYPGMVFDGRNRRGLVR  61

Query  67   WTTTCTVTDADPGRVFAFDVRSGII-------PISRWQYGIVATE-HGCRVTESTWDRRP  118
            WTT CTVT A+PG  FAF VR+  +       PI+ W+Y   A    G RVTE+  D R 
Sbjct  62   WTTRCTVTAAEPGERFAFKVRAIGLRRPVVRGPIATWEYRFAAEPGGGTRVTETWTDDRR  121

Query  119  SWFRAVARM----ATGVKDRASVNTEHIRRTLQRLKDRAE  154
             W  A A +     T  +  A     +I  TL+R  +  E
Sbjct  122  GWPDAAAWLFDHAVTSGRSFADFQRRNIAATLRRFAESCE  161


>gi|308369548|ref|ZP_07418223.2| hypothetical protein TMBG_00416 [Mycobacterium tuberculosis SUMu002]
 gi|308370847|ref|ZP_07422949.2| hypothetical protein TMCG_02923 [Mycobacterium tuberculosis SUMu003]
 gi|308372078|ref|ZP_07427314.2| hypothetical protein TMDG_03915 [Mycobacterium tuberculosis SUMu004]
 13 more sequence titles
 Length=156

 Score = 65.9 bits (159),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 53/151 (36%), Positives = 68/151 (46%), Gaps = 6/151 (3%)

Query  10   TVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKG-DDVRKGAVFVG---RNENGGR  65
            + TV + A PD ++ LI D+      + E    +   G      GA F G   RN  G  
Sbjct  8    SATVHMAAPPDKIWTLIADVRNTGRFSPETFEAEWLDGATGPALGARFRGHVRRNGIGPV  67

Query  66   RWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVA  125
             WT  C VT  +PGR F F V  G  P++ W Y +  T  G  VTES +   PS    V 
Sbjct  68   YWTV-CEVTACEPGREFGFAVLLGDRPVNNWHYRLTPTADGTEVTES-FRLPPSVLTTVY  125

Query  126  RMATGVKDRASVNTEHIRRTLQRLKDRAEAG  156
                G   R   N   + +TLQR+KD  EAG
Sbjct  126  YRVFGGWLRQRRNIRDMTKTLQRIKDLVEAG  156


>gi|326903486|gb|EGE50419.1| hypothetical protein TBPG_01361 [Mycobacterium tuberculosis W-148]
Length=152

 Score = 65.9 bits (159),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 53/151 (36%), Positives = 68/151 (46%), Gaps = 6/151 (3%)

Query  10   TVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKG-DDVRKGAVFVG---RNENGGR  65
            + TV + A PD ++ LI D+      + E    +   G      GA F G   RN  G  
Sbjct  4    SATVHMAAPPDKIWTLIADVRNTGRFSPETFEAEWLDGATGPALGARFRGHVRRNGIGPV  63

Query  66   RWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVA  125
             WT  C VT  +PGR F F V  G  P++ W Y +  T  G  VTES +   PS    V 
Sbjct  64   YWTV-CEVTACEPGREFGFAVLLGDRPVNNWHYRLTPTADGTEVTES-FRLPPSVLTTVY  121

Query  126  RMATGVKDRASVNTEHIRRTLQRLKDRAEAG  156
                G   R   N   + +TLQR+KD  EAG
Sbjct  122  YRVFGGWLRQRRNIRDMTKTLQRIKDLVEAG  152


>gi|15841353|ref|NP_336390.1| hypothetical protein MT1931.1 [Mycobacterium tuberculosis CDC1551]
 gi|31793074|ref|NP_855567.1| hypothetical protein Mb1915c [Mycobacterium bovis AF2122/97]
 gi|121637787|ref|YP_978010.1| hypothetical protein BCG_1920c [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 50 more sequence titles
 Length=158

 Score = 65.9 bits (159),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 53/151 (36%), Positives = 68/151 (46%), Gaps = 6/151 (3%)

Query  10   TVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKG-DDVRKGAVFVG---RNENGGR  65
            + TV + A PD ++ LI D+      + E    +   G      GA F G   RN  G  
Sbjct  10   SATVHMAAPPDKIWTLIADVRNTGRFSPETFEAEWLDGATGPALGARFRGHVRRNGIGPV  69

Query  66   RWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVA  125
             WT  C VT  +PGR F F V  G  P++ W Y +  T  G  VTES +   PS    V 
Sbjct  70   YWTV-CEVTACEPGREFGFAVLLGDRPVNNWHYRLTPTADGTEVTES-FRLPPSVLTTVY  127

Query  126  RMATGVKDRASVNTEHIRRTLQRLKDRAEAG  156
                G   R   N   + +TLQR+KD  EAG
Sbjct  128  YRVFGGWLRQRRNIRDMTKTLQRIKDLVEAG  158


>gi|134096650|ref|YP_001102311.1| hypothetical protein SACE_0032 [Saccharopolyspora erythraea NRRL 
2338]
 gi|291005696|ref|ZP_06563669.1| hypothetical protein SeryN2_14344 [Saccharopolyspora erythraea 
NRRL 2338]
 gi|133909273|emb|CAL99385.1| hypothetical protein SACE_0032 [Saccharopolyspora erythraea NRRL 
2338]
Length=166

 Score = 63.9 bits (154),  Expect = 8e-09, Method: Compositional matrix adjust.
 Identities = 35/105 (34%), Positives = 53/105 (51%), Gaps = 2/105 (1%)

Query  9    VTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWT  68
            +  T E+DA+PD VY +++D+  +   + E    +  +G     G+ F G N  GG  WT
Sbjct  11   IEATTEVDASPDEVYRVVSDITRMGEWSPECTGGEWLRGQPGAAGSRFHGHNRAGGETWT  70

Query  69   TTCTVTDADPGRVFAFDVRSGI--IPISRWQYGIVATEHGCRVTE  111
            T C V  A PGR FA+ V +      +S W + I     GC +T+
Sbjct  71   TECEVVAAVPGREFAWAVLTYARSPEVSVWSFAIEPDGDGCVLTQ  115


>gi|15828098|ref|NP_302361.1| hypothetical protein ML2031 [Mycobacterium leprae TN]
 gi|221230575|ref|YP_002503991.1| hypothetical protein MLBr_02031 [Mycobacterium leprae Br4923]
 gi|13093652|emb|CAC30986.1| conserved hypothetical protein [Mycobacterium leprae]
 gi|219933682|emb|CAR72128.1| conserved hypothetical protein [Mycobacterium leprae Br4923]
Length=151

 Score = 63.2 bits (152),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 54/153 (36%), Positives = 73/153 (48%), Gaps = 13/153 (8%)

Query  10   TVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAV------FVGRNENG  63
            +VTV + A  D V+ LI D+      + E    +    DDV   A+       V RNE G
Sbjct  4    SVTVHMAAPADKVWNLIADVRNTGRFSPETFEAEWL--DDVTGPALNAKFRGHVRRNEIG  61

Query  64   GRRWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTEST-WDRRPSWFR  122
               WTT C VT  +PGR F F V  G  P++ W Y +V +  G  VTES  ++R P    
Sbjct  62   PVYWTT-CKVTACEPGREFGFTVLLGNKPVNNWHYRLVTSGDGTYVTESFRFNRSP--LL  118

Query  123  AVARMATGVKDRASVNTEHIRRTLQRLKDRAEA  155
             V  +  G   R   N   + +TL+R+KD  EA
Sbjct  119  TVYWLLGGFL-RKRRNIRDMTKTLRRIKDVVEA  150


>gi|118619838|ref|YP_908170.1| hypothetical protein MUL_4783 [Mycobacterium ulcerans Agy99]
 gi|183980368|ref|YP_001848659.1| hypothetical protein MMAR_0337 [Mycobacterium marinum M]
 gi|118571948|gb|ABL06699.1| conserved hypothetical protein [Mycobacterium ulcerans Agy99]
 gi|183173694|gb|ACC38804.1| conserved hypothetical protein [Mycobacterium marinum M]
Length=174

 Score = 62.8 bits (151),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 37/111 (34%), Positives = 62/111 (56%), Gaps = 2/111 (1%)

Query  5    DGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKG-DDVRKGAVFVGRNENG  63
            D P+V  +  IDA P+ V+ LI+D+  + +L+ E+ A++   G  + R GA F+G N++ 
Sbjct  13   DRPTVEASTWIDAEPERVWSLISDIALMPTLSNELQAVEWVGGVSEPRVGARFIGHNQHE  72

Query  64   GR-RWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTEST  113
               +WT+T  V   DP R FA+ V     P + W++ +V  + G  +T  T
Sbjct  73   AFGQWTSTSQVVRCDPPREFAWAVGEPDYPAAVWRFRLVPRDGGTNLTYRT  123


>gi|315443123|ref|YP_004076002.1| polyketide cyclase / dehydrase and lipid transport [Mycobacterium 
sp. Spyr1]
 gi|315261426|gb|ADT98167.1| Polyketide cyclase / dehydrase and lipid transport [Mycobacterium 
sp. Spyr1]
Length=154

 Score = 62.4 bits (150),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 48/143 (34%), Positives = 67/143 (47%), Gaps = 9/143 (6%)

Query  19   PDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWTTTCTVTDADP  78
            P  +Y L++D+      +    A    +G   R+GA F GRNE   R W T   V  A+P
Sbjct  16   PSRLYALVSDVTRTGEWSPVCKACWWDEGAGPREGAWFTGRNELPERTWETRSQVVAAEP  75

Query  79   GRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWF-----RAVARMATGVKD  133
            GR FA++V  G +   RW Y +VA   G  +TES W+  P        R  A     +  
Sbjct  76   GREFAWEVNDGWV---RWGYILVADGDGTLLTES-WEFLPKGIDGFHERFGAEADAEIAK  131

Query  134  RASVNTEHIRRTLQRLKDRAEAG  156
            R+    + I  TL+ +K  AEAG
Sbjct  132  RSDAARDGIPATLEAIKRIAEAG  154


>gi|342859532|ref|ZP_08716185.1| cyclase/dehydrase [Mycobacterium colombiense CECT 3035]
 gi|342132664|gb|EGT85884.1| cyclase/dehydrase [Mycobacterium colombiense CECT 3035]
Length=151

 Score = 62.4 bits (150),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 50/151 (34%), Positives = 67/151 (45%), Gaps = 7/151 (4%)

Query  10   TVTVEIDANPDLVYGLITDLPTLASLAEEVV-AMQLRKGDDVRKGAVFVG---RNENGGR  65
            + TV + A    ++ LI D+      + EV  A  L        GA F G   RNE G  
Sbjct  4    SATVHMAAPAAKIWDLIADVRNTGKFSPEVFEAEWLGDATGPALGAKFRGHVKRNEMGPV  63

Query  66   RWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVA  125
             WTT C VT  +PGR F F V  G  P++ W Y +  ++ G  VTES       W     
Sbjct  64   YWTT-CKVTACEPGREFGFTVLLGDRPVNNWHYRLAPSDGGTDVTESFRLNPAPWLGVYW  122

Query  126  RMATGVKDRASVNTEHIRRTLQRLKDRAEAG  156
                 ++ R   N   + +TL R+KD  EAG
Sbjct  123  LFGGFLRKRR--NIRDMTKTLNRIKDVVEAG  151


>gi|226304668|ref|YP_002764626.1| hypothetical protein RER_11790 [Rhodococcus erythropolis PR4]
 gi|226183783|dbj|BAH31887.1| conserved hypothetical protein [Rhodococcus erythropolis PR4]
Length=175

 Score = 61.2 bits (147),  Expect = 5e-08, Method: Compositional matrix adjust.
 Identities = 52/146 (36%), Positives = 70/146 (48%), Gaps = 14/146 (9%)

Query  22   VYGLITDLPTLASLAEEVVAMQLRKGD--DVRKGAVFVGRNENGGRRWTTTCTVTDADPG  79
            +Y LI+D   +   + E +   LR GD      G  F G N+ G  +WTT CTVT AD G
Sbjct  20   LYELISDPTRMGDWSPENLGATLR-GDRESAFLGMEFDGHNKRGRAQWTTRCTVTAADAG  78

Query  80   RVFAFDVRS-GI------IPISRWQYGIVATEHGCRVTESTWDRRPSW--FRA--VARMA  128
            ++F F V   G+        I+ W+Y       G RVTE+  D R  W  F A    ++A
Sbjct  79   KLFEFRVHKIGLATPRISAAIATWRYRFQPVPGGTRVTETWIDDRRGWPDFAADIFDKVA  138

Query  129  TGVKDRASVNTEHIRRTLQRLKDRAE  154
            TG K  A     +IR+TL  +K   E
Sbjct  139  TGGKTFADFQRGNIRKTLLNIKSAVE  164


>gi|120405594|ref|YP_955423.1| hypothetical protein Mvan_4642 [Mycobacterium vanbaalenii PYR-1]
 gi|119958412|gb|ABM15417.1| conserved hypothetical protein [Mycobacterium vanbaalenii PYR-1]
Length=149

 Score = 60.5 bits (145),  Expect = 8e-08, Method: Compositional matrix adjust.
 Identities = 46/156 (30%), Positives = 73/156 (47%), Gaps = 15/156 (9%)

Query  9    VTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWT  68
            ++ ++ +  +P+ +Y L+ D+  +   +    A     G   + GA F GRN    R W 
Sbjct  1    MSESISVAVSPEQLYALVADVTRMGEWSPVCRACWWDDGAGPQVGAWFTGRNVTPERTWE  60

Query  69   TTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVARM-  127
              C V  A+PGR FA++V  G    + W Y + A + G R+TES W+  P     VA + 
Sbjct  61   ARCQVVAAEPGRRFAWEVNHG---WAYWGYEMAAEDGGTRLTES-WELLP---EGVAGLR  113

Query  128  ----ATG---VKDRASVNTEHIRRTLQRLKDRAEAG  156
                 TG   +  R+      I  TL+ +K  AE+G
Sbjct  114  ERYGETGDAEIAKRSEAARSGIPATLEAIKRTAESG  149


>gi|333990612|ref|YP_004523226.1| hypothetical protein JDM601_1972 [Mycobacterium sp. JDM601]
 gi|333486580|gb|AEF35972.1| conserved hypothetical protein [Mycobacterium sp. JDM601]
Length=144

 Score = 60.1 bits (144),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 47/142 (34%), Positives = 69/142 (49%), Gaps = 6/142 (4%)

Query  17   ANPDLVYGLITDLPTLASLAEEVVAMQLRKG-DDVRKGAVFVG---RNENGGRRWTTTCT  72
            A  + ++ L+ D+  +   + E    +   G      GA F G   RN  G   WTT C 
Sbjct  3    APAERIWDLVADVRNIGRFSPETFEAEWLDGATGPEVGARFRGHVRRNGIGPVYWTT-CR  61

Query  73   VTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVARMATGVK  132
            VT+ +P RVF F+V +G   ++RW Y +  T  G  VTES +    S+  +V     G  
Sbjct  62   VTECEPNRVFGFEVLAGDRAVNRWSYELTPTADGTHVTES-FRLADSFLTSVYYYLFGGF  120

Query  133  DRASVNTEHIRRTLQRLKDRAE  154
             R   N   +RRTL+R++D AE
Sbjct  121  LRQRNNIRDMRRTLERIRDVAE  142


>gi|229494359|ref|ZP_04388122.1| conserved hypothetical protein [Rhodococcus erythropolis SK121]
 gi|229318721|gb|EEN84579.1| conserved hypothetical protein [Rhodococcus erythropolis SK121]
Length=123

 Score = 59.7 bits (143),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 45/110 (41%), Positives = 58/110 (53%), Gaps = 11/110 (10%)

Query  56   FVGRNENGGRRWTTTCTVTDADPGRVFAFDVRS-GI----IP--ISRWQYGIVATEHGCR  108
            F G N+ G  +WTT CTVT A+ G++F F V   G+    IP  I+ WQY       G R
Sbjct  3    FDGHNKRGRAQWTTRCTVTAAEAGKLFEFRVHKIGLGTPRIPASIATWQYRFSPVPDGTR  62

Query  109  VTESTWDRRPSW--FRA--VARMATGVKDRASVNTEHIRRTLQRLKDRAE  154
            VTE+  D R  W  F A    ++ATG K  A     +IR+TL  LK+  E
Sbjct  63   VTETWTDDRRGWPDFAADMFDKIATGGKTFADFQRGNIRKTLLNLKNAVE  112


>gi|296164902|ref|ZP_06847458.1| cyclase/dehydrase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295899744|gb|EFG79194.1| cyclase/dehydrase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=155

 Score = 58.9 bits (141),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 48/151 (32%), Positives = 69/151 (46%), Gaps = 7/151 (4%)

Query  10   TVTVEIDANPDLVYGLITDLPTLASLAEEVV-AMQLRKGDDVRKGAVFVG---RNENGGR  65
            + TV + A+ + ++ LI ++  +   + EV  A  L        GA F G   RNE G  
Sbjct  8    SATVHMAASANKIWDLIANVDNIGRFSPEVFEAEWLGDATGPALGAKFRGHVRRNEIGPV  67

Query  66   RWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVA  125
             WTT C VT  +PGR F F V  G   ++ W Y +  +  G  VTES       W     
Sbjct  68   YWTT-CEVTACEPGREFGFAVLLGDRAVNNWHYRLAPSGGGTDVTESFRLSPAPWLGLYW  126

Query  126  RMATGVKDRASVNTEHIRRTLQRLKDRAEAG  156
             +   ++ R   N   + +TL R+KD  EAG
Sbjct  127  LLGGFLRKRR--NVRDMTKTLNRIKDVVEAG  155


>gi|345012246|ref|YP_004814600.1| polyketide cyclase/dehydrase [Streptomyces violaceusniger Tu 
4113]
 gi|344038595|gb|AEM84320.1| Polyketide cyclase/dehydrase [Streptomyces violaceusniger Tu 
4113]
Length=169

 Score = 58.5 bits (140),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 32/98 (33%), Positives = 45/98 (46%), Gaps = 0/98 (0%)

Query  15   IDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDVRKGAVFVGRNENGGRRWTTTCTVT  74
            +DA P  VYGL++D+  +   +     +    G     GA F GRN   G+ WTT   + 
Sbjct  27   VDAAPARVYGLVSDVSAIGRWSPNADDVAFEPGAGPWAGAWFGGRNRRNGKEWTTRSQIV  86

Query  75   DADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTES  112
             ADPG  F F V      I RW++ +     G  V +S
Sbjct  87   RADPGAAFGFVVGGAENGIVRWEWTLTPRGRGTVVQQS  124


>gi|296167317|ref|ZP_06849719.1| cyclase/dehydrase [Mycobacterium parascrofulaceum ATCC BAA-614]
 gi|295897261|gb|EFG76865.1| cyclase/dehydrase [Mycobacterium parascrofulaceum ATCC BAA-614]
Length=174

 Score = 58.5 bits (140),  Expect = 3e-07, Method: Compositional matrix adjust.
 Identities = 33/108 (31%), Positives = 60/108 (56%), Gaps = 2/108 (1%)

Query  5    DGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDDV-RKGAVFVGRNENG  63
            D P+V  +  IDA+P  V+ L++D+  + +L+ E+ A++  +G D  R GA FVG N+N 
Sbjct  13   DKPTVEASTWIDADPARVWSLVSDIKLMPTLSNELQAVEWAEGADAPRVGARFVGHNQNE  72

Query  64   GR-RWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVT  110
               +W++T  +   D  R FA+ V     P + W++ +   + G  ++
Sbjct  73   AFGQWSSTSQIVACDEPREFAWAVGEPERPAAAWRFRLTPRDGGTDLS  120


>gi|15609020|ref|NP_216399.1| hypothetical protein Rv1883c [Mycobacterium tuberculosis H37Rv]
 gi|148661689|ref|YP_001283212.1| hypothetical protein MRA_1894 [Mycobacterium tuberculosis H37Ra]
 gi|167970366|ref|ZP_02552643.1| hypothetical protein MtubH3_20988 [Mycobacterium tuberculosis 
H37Ra]
 8 more sequence titles
 Length=153

 Score = 58.2 bits (139),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 50/151 (34%), Positives = 65/151 (44%), Gaps = 11/151 (7%)

Query  10   TVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKG-DDVRKGAVFVG---RNENGGR  65
            + TV + A PD ++ LI D+      + E    +   G      GA F G   RN  G  
Sbjct  10   SATVHMAAPPDKIWTLIADVRNTGRFSPETFEAEWLDGATGPALGARFRGHVRRNGIGPV  69

Query  66   RWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTWDRRPSWFRAVA  125
             WT        +PGR F F V  G  P++ W Y +  T  G  VTES +   PS    V 
Sbjct  70   YWTV------CEPGREFGFAVLLGDRPVNNWHYRLTPTADGTEVTES-FRLPPSVLTTVY  122

Query  126  RMATGVKDRASVNTEHIRRTLQRLKDRAEAG  156
                G   R   N   + +TLQR+KD  EAG
Sbjct  123  YRVFGGWLRQRRNIRDMTKTLQRIKDLVEAG  153


>gi|237785071|ref|YP_002905776.1| hypothetical protein ckrop_0456 [Corynebacterium kroppenstedtii 
DSM 44385]
 gi|237757983|gb|ACR17233.1| hypothetical protein ckrop_0456 [Corynebacterium kroppenstedtii 
DSM 44385]
Length=188

 Score = 58.2 bits (139),  Expect = 4e-07, Method: Compositional matrix adjust.
 Identities = 41/128 (33%), Positives = 58/128 (46%), Gaps = 9/128 (7%)

Query  1    MPDPDGPSVTVTVEIDANPDLVYGLITDLPTLASLAEEVVAMQLRKGDD------VRKGA  54
            M +PD     V+V IDA PD VY +++D+      +    A   ++ DD         GA
Sbjct  19   MFNPDDFRRRVSVTIDATPDEVYNVVSDISRTGEWSPVCKATWWKERDDGTTPAEPEVGA  78

Query  55   VFVGRNENGGRRWTTTCTVTDADPGRVFAFDVRSGIIPISRWQYGIVATEHGCRVTESTW  114
             FVG NE   R W T   VT A+  +VF++ V  G++    W Y I   + G      TW
Sbjct  79   WFVGHNETPKRTWETESVVTAAERPKVFSWAVNGGVV---EWGYEIEPADDGGSTLTETW  135

Query  115  DRRPSWFR  122
            +     FR
Sbjct  136  EVTQEGFR  143



Lambda     K      H
   0.319    0.135    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 130065254832


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40