BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2817c Length=338 Score E Sequences producing significant alignments: (Bits) Value gi|167968189|ref|ZP_02550466.1| hypothetical protein MtubH3_0920... 695 0.0 gi|15609954|ref|NP_217333.1| hypothetical protein Rv2817c [Mycob... 694 0.0 gi|298526284|ref|ZP_07013693.1| conserved hypothetical protein [... 692 0.0 gi|331004038|ref|ZP_08327520.1| CRISPR-associated protein cas1 [... 223 3e-56 gi|224543481|ref|ZP_03684020.1| hypothetical protein CATMIT_0269... 210 3e-52 gi|229826471|ref|ZP_04452540.1| hypothetical protein GCWU000182_... 206 4e-51 gi|291460045|ref|ZP_06599435.1| CRISPR-associated protein Cas1 [... 204 2e-50 gi|240143668|ref|ZP_04742269.1| CRISPR-associated protein Cas1 [... 199 7e-49 gi|294782686|ref|ZP_06748012.1| CRISPR-associated protein Cas1 [... 196 7e-48 gi|253578035|ref|ZP_04855307.1| CRISPR-associated protein cas1 [... 192 5e-47 gi|340752436|ref|ZP_08689235.1| CRISPR-associated protein cas1 [... 192 7e-47 gi|315925051|ref|ZP_07921268.1| conserved hypothetical protein [... 191 1e-46 gi|121533432|ref|ZP_01665260.1| CRISPR-associated protein Cas1 [... 189 6e-46 gi|339890605|gb|EGQ79706.1| hypothetical protein HMPREF9094_1263... 186 4e-45 gi|296133514|ref|YP_003640761.1| CRISPR-associated protein Cas1 ... 186 6e-45 gi|121533442|ref|ZP_01665270.1| CRISPR-associated protein Cas1 [... 185 1e-44 gi|114567264|ref|YP_754418.1| hypothetical protein Swol_1749 [Sy... 181 1e-43 gi|237741581|ref|ZP_04572062.1| CRISPR-associated protein [Fusob... 181 2e-43 gi|258645680|ref|ZP_05733149.1| CRISPR-associated protein Cas1 [... 177 2e-42 gi|339278110|emb|CCC19858.1| CRISPR-associated protein cas1 [Str... 176 7e-42 gi|325695839|gb|EGD37730.1| hypothetical protein HMPREF9384_1727... 174 3e-41 gi|294794257|ref|ZP_06759393.1| CRISPR-associated protein Cas1 [... 170 3e-40 gi|333976353|gb|EGL77222.1| CRISPR-associated endonuclease Cas1 ... 169 4e-40 gi|238018273|ref|ZP_04598699.1| hypothetical protein VEIDISOL_00... 168 1e-39 gi|116627764|ref|YP_820383.1| hypothetical protein STER_0970 [St... 167 3e-39 gi|303231960|ref|ZP_07318668.1| CRISPR-associated endonuclease C... 166 4e-39 gi|342214546|ref|ZP_08707233.1| CRISPR-associated endonuclease C... 164 1e-38 gi|341822659|emb|CCC73583.1| CRISPR-associated endonuclease CaS1... 163 3e-38 gi|159899002|ref|YP_001545249.1| CRISPR-associated Cas1 family p... 161 2e-37 gi|291539925|emb|CBL13036.1| CRISPR-associated protein Cas1 [Ros... 159 6e-37 gi|125718075|ref|YP_001035208.1| hypothetical protein SSA_1255 [... 159 7e-37 gi|327470946|gb|EGF16402.1| CRISPR-associated protein cas1 [Stre... 158 1e-36 gi|323141545|ref|ZP_08076431.1| CRISPR-associated endonuclease C... 154 2e-35 gi|309791951|ref|ZP_07686429.1| CRISPR-associated Cas1 family pr... 154 3e-35 gi|334126733|ref|ZP_08500681.1| CRISPR-associated protein Cas1 [... 154 3e-35 gi|313894905|ref|ZP_07828465.1| CRISPR-associated endonuclease C... 154 3e-35 gi|327474433|gb|EGF19839.1| hypothetical protein HMPREF9391_0559... 152 8e-35 gi|209526394|ref|ZP_03274922.1| CRISPR-associated protein Cas1 [... 151 1e-34 gi|156741961|ref|YP_001432090.1| CRISPR-associated Cas1 family p... 151 2e-34 gi|163846146|ref|YP_001634190.1| CRISPR-associated Cas1 family p... 150 2e-34 gi|291568436|dbj|BAI90708.1| CRISPR-associated protein Cas1 [Art... 148 1e-33 gi|284052685|ref|ZP_06382895.1| hypothetical protein AplaP_14548... 148 1e-33 gi|320161859|ref|YP_004175084.1| hypothetical protein ANT_24580 ... 147 2e-33 gi|312899092|ref|ZP_07758470.1| CRISPR-associated protein Cas1 [... 144 1e-32 gi|219850296|ref|YP_002464729.1| CRISPR-associated protein Cas1 ... 144 2e-32 gi|337286709|ref|YP_004626182.1| CRISPR-associated protein Cas1 ... 142 9e-32 gi|312278318|gb|ADQ62975.1| CRISPR-associated protein, Cas1 fami... 141 1e-31 gi|292669134|ref|ZP_06602560.1| CRISPR-associated fusion protein... 140 3e-31 gi|328953000|ref|YP_004370334.1| CRISPR-associated protein Cas1 ... 139 5e-31 gi|254417359|ref|ZP_05031101.1| CRISPR-associated protein Cas1 [... 139 5e-31 >gi|167968189|ref|ZP_02550466.1| hypothetical protein MtubH3_09204 [Mycobacterium tuberculosis H37Ra] gi|253798098|ref|YP_003031099.1| hypothetical protein TBMG_01156 [Mycobacterium tuberculosis KZN 1435] gi|254551879|ref|ZP_05142326.1| hypothetical protein Mtube_15707 [Mycobacterium tuberculosis '98-R604 INH-RIF-EM'] 22 more sequence titles Length=341 Score = 695 bits (1793), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/338 (100%), Positives = 338/338 (100%), Gaps = 0/338 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE Sbjct 4 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 63 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR Sbjct 64 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 123 Query 121 AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRS 180 AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRS Sbjct 124 AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRS 183 Query 181 TRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240 TRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP Sbjct 184 TRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 243 Query 241 IIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHR 300 IIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHR Sbjct 244 IIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHR 303 Query 301 YTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA 338 YTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA Sbjct 304 YTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA 341 >gi|15609954|ref|NP_217333.1| hypothetical protein Rv2817c [Mycobacterium tuberculosis H37Rv] gi|15842358|ref|NP_337395.1| hypothetical protein MT2884 [Mycobacterium tuberculosis CDC1551] gi|31793993|ref|NP_856486.1| hypothetical protein Mb2841c [Mycobacterium bovis AF2122/97] 41 more sequence titles Length=338 Score = 694 bits (1790), Expect = 0.0, Method: Compositional matrix adjust. Identities = 338/338 (100%), Positives = 338/338 (100%), Gaps = 0/338 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE Sbjct 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR Sbjct 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 Query 121 AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRS 180 AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRS Sbjct 121 AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRS 180 Query 181 TRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240 TRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP Sbjct 181 TRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240 Query 241 IIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHR 300 IIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHR Sbjct 241 IIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHR 300 Query 301 YTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA 338 YTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA Sbjct 301 YTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA 338 >gi|298526284|ref|ZP_07013693.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] gi|298496078|gb|EFI31372.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A] Length=338 Score = 692 bits (1787), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/338 (99%), Positives = 338/338 (100%), Gaps = 0/338 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE Sbjct 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 RDIQLFTTDGHYQGRISTPD+SYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR Sbjct 61 RDIQLFTTDGHYQGRISTPDLSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 Query 121 AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRS 180 AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRS Sbjct 121 AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRS 180 Query 181 TRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240 TRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP Sbjct 181 TRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240 Query 241 IIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHR 300 IIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHR Sbjct 241 IIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHR 300 Query 301 YTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA 338 YTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA Sbjct 301 YTFQYALDLQLQSLVRVIEAGHPSRLVDIDITSEPSGA 338 >gi|331004038|ref|ZP_08327520.1| CRISPR-associated protein cas1 [Lachnospiraceae oral taxon 107 str. F0167] gi|330411624|gb|EGG91032.1| CRISPR-associated protein cas1 [Lachnospiraceae oral taxon 107 str. F0167] Length=334 Score = 223 bits (568), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 110/323 (35%), Positives = 190/323 (59%), Gaps = 2/323 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LY+++ S+I+ + G++I+ + + +P ETL+ I +FG +MT P L++ Sbjct 1 MACLYITEQGSKITTSAGKIIIECRDGTKKSFPKETLESIMIFGNSSMTVPVKKFCLEKG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 + +T G Y GR+++ YA RL++QV+ +D + CL +K+I + KI NQ+ +++ Sbjct 61 IKVTFLSTKGKYFGRLASTSHFYAERLKKQVYLSDSNSDCLEFAKKIQAAKIHNQRIILK 120 Query 121 AHT--SGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQG 178 + S +D+ E + + + + S+ E+ G+EG AA+ YF AL ++ +EFAF G Sbjct 121 RYEKHSDKDIKEELDRISIYENEISQCKSVDEVLGYEGMAAREYFKALSKIIREEFAFDG 180 Query 179 RSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWR 238 RS +PPLDAFNSM+S GY++++ I +E L+ YIGF+H+ R H TL SD++E WR Sbjct 181 RSRQPPLDAFNSMISFGYTIVFYEIFAEVESRDLSPYIGFIHKIKRNHPTLVSDMLEEWR 240 Query 239 APIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDP 298 A ++D T+L LI + FS + +TGAV+ + A + R ++ + Y++ Sbjct 241 ALLVDSTILSLIQGNEISIYEFSHDEETGAVYLSDNAIKICVRKIEEKMRKEMNYLEYLD 300 Query 299 HRYTFQYALDLQLQSLVRVIEAG 321 +F+ A+ Q++SL I+ G Sbjct 301 SPVSFRRAIWWQIKSLAGCIDNG 323 >gi|224543481|ref|ZP_03684020.1| hypothetical protein CATMIT_02690 [Catenibacterium mitsuokai DSM 15897] gi|224523608|gb|EEF92713.1| hypothetical protein CATMIT_02690 [Catenibacterium mitsuokai DSM 15897] Length=332 Score = 210 bits (534), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 121/320 (38%), Positives = 177/320 (56%), Gaps = 4/320 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LY+ S I D R+ V ++ P+E++DGITL G +TT I E LK+ Sbjct 1 MSILYIDKSDCVIGKQDNRITVKYKDGMFRTIPVESIDGITLLGHAQVTTQCIQECLKKG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 + F+ GHY GR+S+ A R+Q D P F L LSK+I+ KI NQ ++R Sbjct 61 ISLSYFSKGGHYFGRLSSTGHIKASLQRKQAGLYDQP-FALELSKKIIYAKIHNQIVVLR 119 Query 121 AHT--SGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQG 178 ++ + ++++ MK +L V+ ++ EL G+EG+AA+ YF L + + F F+G Sbjct 120 RYSRSTNHNISDIELHMKSALRKVNYVKNIEELMGYEGSAARYYFKGLSMCIDEAFKFEG 179 Query 179 RSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWR 238 RS RPP DAFNSM+SLGYS+L + G IE LNAY GFLH+D+ H TLASD+ME WR Sbjct 180 RSKRPPHDAFNSMLSLGYSILMNELYGEIEIKGLNAYFGFLHRDAEKHPTLASDMMEEWR 239 Query 239 APIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDP 298 A +ID TV+ +I V F + G V+ ++A + N+ Y+ Sbjct 240 AVLIDSTVMSMINGHEVHIDEFYSDDGEG-VYIFKQALNKFIKKLENKFQICQKYLDYID 298 Query 299 HRYTFQYALDLQLQSLVRVI 318 + +F+ A+ Q+ SLV I Sbjct 299 YPVSFRSAISFQMSSLVDAI 318 >gi|229826471|ref|ZP_04452540.1| hypothetical protein GCWU000182_01844 [Abiotrophia defectiva ATCC 49176] gi|229789341|gb|EEP25455.1| hypothetical protein GCWU000182_01844 [Abiotrophia defectiva ATCC 49176] Length=340 Score = 206 bits (524), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 111/324 (35%), Positives = 181/324 (56%), Gaps = 2/324 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV + S+I G+ I+ ++ P E L+ I++FG +TT I L++ Sbjct 7 MSCLYVVEQGSKIKHIGGQFILEVKDGENRVVPDEILESISIFGNSVLTTQAIKACLEKN 66 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 ++ +T G Y G++ + + RL+ Q + +D+ CL +K I+ KI NQ ++R Sbjct 67 INVSFLSTKGRYFGKLMSNTATNPDRLKAQAYLSDNIDECLKFAKIILKAKINNQDVILR 126 Query 121 --AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQG 178 A +S D++ I+ +K +++ + ++ G+EG AA+ YF AL L+ EF F G Sbjct 127 RYAKSSEADISSHIKDLKIYEEHIEKGKDINKIMGYEGIAARTYFEALSKLIKPEFKFSG 186 Query 179 RSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWR 238 R+ RPP DAFNSM+SLGYSL+Y I IE +L+ YIGF+H+ H L SDL+E WR Sbjct 187 RNKRPPKDAFNSMLSLGYSLIYNEIFSEIENRNLSPYIGFIHKLKDRHPALVSDLIEEWR 246 Query 239 APIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDP 298 A ++D T++ LI + F+K+ + AVF + A + I R N++ Y++ Sbjct 247 AVLVDATMMSLIQGNEILIEEFTKDEYSEAVFISDLAVKQIVRKIENKLRSQNNYLEYLN 306 Query 299 HRYTFQYALDLQLQSLVRVIEAGH 322 +F+ A+ Q++SL IE+G+ Sbjct 307 EPISFRKAIWWQVKSLASCIESGN 330 >gi|291460045|ref|ZP_06599435.1| CRISPR-associated protein Cas1 [Oribacterium sp. oral taxon 078 str. F0262] gi|291417386|gb|EFE91105.1| CRISPR-associated protein Cas1 [Oribacterium sp. oral taxon 078 str. F0262] Length=332 Score = 204 bits (518), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 119/326 (37%), Positives = 177/326 (55%), Gaps = 6/326 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV + + I R V ++ P ETL+ I +FG+ +TT + E LKR Sbjct 1 MSYLYVCEQGAVIGCEANRFQVCYKDGMLKSVPGETLEVIEIFGKVQLTTQCMTECLKRG 60 Query 61 RDIQLFTTDGHYQGR-ISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI 119 + ++++G Y GR IST V+ A RQ+ F L++RI+ KI NQ ++ Sbjct 61 ITVLFYSSNGAYYGRLISTNHVNVA---RQRSQAALKEEFKAGLARRIIRAKIRNQTVIL 117 Query 120 RAHTSGQDVA--ESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 R + Q A ++ M +D +G ++ G+EG AA+ YF ALG LV +EF F+ Sbjct 118 RRYARKQAAAVEGTVSEMLRLAEKLDWTGDTEKIMGYEGMAARVYFAALGGLVDREFCFK 177 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 GRS RPP D FNS++SLGYS+L I G +E LN Y G LH+D H TLASDLME W Sbjct 178 GRSKRPPKDPFNSLISLGYSILLGEIYGKLEGKGLNPYFGVLHKDREKHPTLASDLMEEW 237 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 RA ++D T + ++ + F ++ +TGAV ++A + R ++ Y+ Sbjct 238 RAVLVDSTAMSILNGHELHREDFFRDEETGAVLLVKDAFKEYLRKLEAKLHTDMKYLSYV 297 Query 298 PHRYTFQYALDLQLQSLVRVIEAGHP 323 +R F+ ALDLQ+ L + IE+ +P Sbjct 298 DYRVNFRSALDLQVDRLAKAIESENP 323 >gi|240143668|ref|ZP_04742269.1| CRISPR-associated protein Cas1 [Roseburia intestinalis L1-82] gi|257204345|gb|EEV02630.1| CRISPR-associated protein Cas1 [Roseburia intestinalis L1-82] Length=334 Score = 199 bits (505), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 117/322 (37%), Positives = 172/322 (54%), Gaps = 4/322 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYVS+ + I R V ++ P ETL+ I +FG +TT + E LKR Sbjct 1 MSYLYVSEQGASIGIEANRFQVNYKDGMIKSIPAETLEMIEVFGSVQITTRCLTECLKRG 60 Query 61 RDIQLFTTDGHYQGR-ISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI 119 +I ++T G Y GR IST V+ R R Q + F L +SKRI+ KI NQ ++ Sbjct 61 VNILFYSTSGAYYGRLISTSHVN-VQRQRIQAEIGHNETFKLEMSKRIIDAKIRNQVVVL 119 Query 120 RAHTSG--QDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 R + G +D+ I M++ + + S+ ++ G+EG AAK YF LG L+ ++F F+ Sbjct 120 RRYARGRDEDIHRMIIEMQNMQKKLLYAKSVEQVMGYEGTAAKIYFKVLGKLIDEQFVFE 179 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 GRS RPP+D FNS++SLGYS++ + G IE LN Y G +H+D H TLASDLME W Sbjct 180 GRSRRPPMDPFNSLISLGYSIILNELYGKIEGKGLNPYFGVMHKDREKHPTLASDLMEEW 239 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 RA +ID T L ++ + F D VF ++ R + + Y+ Sbjct 240 RAVLIDTTALSMLNGHELVKEDFYTGIDQPGVFLEKDGFRKYIQKLEGKFRTENRYLSYI 299 Query 298 PHRYTFQYALDLQLQSLVRVIE 319 + +F+ A+DLQ+ V+ IE Sbjct 300 DYSVSFRRAMDLQVNQFVKAIE 321 >gi|294782686|ref|ZP_06748012.1| CRISPR-associated protein Cas1 [Fusobacterium sp. 1_1_41FAA] gi|294481327|gb|EFG29102.1| CRISPR-associated protein Cas1 [Fusobacterium sp. 1_1_41FAA] Length=335 Score = 196 bits (497), Expect = 7e-48, Method: Compositional matrix adjust. Identities = 97/325 (30%), Positives = 176/325 (55%), Gaps = 3/325 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LY+ + + + + R+++ PIE +D + +FG ++T I +L + Sbjct 1 MSNLYIYEQGIVLRYKENRLLITYANDDSKSIPIENIDNVVIFGGIQLSTSCIHNLLAKG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQA-LI 119 + + +G Y GR+ + R R+Q ++DD FCL ++K+ + K NQ+ LI Sbjct 61 IHVTFLSKNGSYFGRLESTSNINIDRQREQFRKSDDKEFCLEIAKKFIKGKGTNQRTILI 120 Query 120 RAHTSGQD--VAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 RA+ ++ +A +I TM + ++ + ++ EL G EG AK YF AL H++ ++++F+ Sbjct 121 RANKELKNEVLATTITTMFGIIKDINDTKTIEELMGIEGYLAKLYFNALNHIIDKKYSFK 180 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 R+ RPP D FN+++S GY+LL+ I + LN Y FLH D H L SDLME W Sbjct 181 TRTKRPPKDPFNAVISFGYTLLHYEIFTILVTKGLNPYAAFLHSDRHKHPALCSDLMEEW 240 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 R+ ++D + L+ + + F + ++G VF ++A F R+ + +YIK Sbjct 241 RSILVDSLAIALLNNNKIAYEDFDFDEESGGVFLNKKACEKFVEQFEKRLRQEVSYIKEV 300 Query 298 PHRYTFQYALDLQLQSLVRVIEAGH 322 P++ +F+ ++ Q+ L++ +EA + Sbjct 301 PYKMSFRRIIEYQVMLLIKALEANN 325 >gi|253578035|ref|ZP_04855307.1| CRISPR-associated protein cas1 [Ruminococcus sp. 5_1_39B_FAA] gi|251850353|gb|EES78311.1| CRISPR-associated protein cas1 [Ruminococcus sp. 5_1_39BFAA] Length=333 Score = 192 bits (489), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 113/327 (35%), Positives = 170/327 (52%), Gaps = 5/327 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV+DS + I V ++ + PIE+LDGIT+ G+ MTT E ++R Sbjct 1 MSLLYVNDSGATIGIEGNCCTVKQKDGSKRMLPIESLDGITIMGQSQMTTQCAEECMQRG 60 Query 61 RDIQLFTTDGHYQGR-ISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI 119 + F+ G Y GR IST V+ R R+Q D F + L+ +I+S KI NQ ++ Sbjct 61 IPVSYFSKGGKYFGRLISTGHVN-VERQRKQCALYD-TGFAVELAMKILSAKIKNQSVVL 118 Query 120 RAH--TSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 R + + G ++ E + + V + E+ GFEG AAK YF L + + F FQ Sbjct 119 RRYEKSKGLNLEEEQKMLAICRNKVLTCDRIEEMIGFEGQAAKYYFKGLSACIDENFTFQ 178 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 GR+ RPP D FNSM+SLGYS+L + +E LN Y GF+H+D+ H TLASD++E W Sbjct 179 GRNRRPPRDEFNSMISLGYSILMNEVYCKVEMKGLNPYFGFIHRDAEKHPTLASDMIEEW 238 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 RA I+D T + +I + F N D + T++ + + Y+K Sbjct 239 RAIIVDATAMSMINGHEILKDHFYFNMDEPGCYITKDGLKLYLNKLERKFQTEVRYLKYV 298 Query 298 PHRYTFQYALDLQLQSLVRVIEAGHPS 324 + +F+ + LQ++ L + IE G S Sbjct 299 DYAVSFRRGIFLQMEHLAKAIEEGDAS 325 >gi|340752436|ref|ZP_08689235.1| CRISPR-associated protein cas1 [Fusobacterium sp. 2_1_31] gi|229422235|gb|EEO37282.1| CRISPR-associated protein cas1 [Fusobacterium sp. 2_1_31] Length=335 Score = 192 bits (488), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 96/324 (30%), Positives = 172/324 (54%), Gaps = 3/324 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LY+ + + + + R+++ PIE +D I +FG ++T + +L + Sbjct 1 MSNLYIYEQGIVLRYKENRLLITYTNDDSKSIPIENIDNIVIFGGIQLSTTCMHNLLAKG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQA-LI 119 + + +G Y GR+ + R R+Q ++DD FCL ++K+ + K NQ+ LI Sbjct 61 IHVTFLSKNGSYFGRLESTSNINIDRQREQFRKSDDKEFCLEIAKKFIKGKATNQRTILI 120 Query 120 RAHTSGQD--VAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 RA+ ++ ++ +I TM + ++ + ++ EL G EG AK YF AL ++ ++++F+ Sbjct 121 RANKELKNDVLSSTITTMFGIIKDINNAKTIEELMGVEGYLAKLYFNALNQIIDKKYSFK 180 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 R+ RPP D FN+++S GY+LL+ I + LN Y FLH D H L SDLME W Sbjct 181 TRTKRPPKDPFNAVISFGYTLLHYEIFTILVTKGLNPYAAFLHSDRHKHPALCSDLMEEW 240 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 RA ++D + L+ + + F + +G VF ++A F R+ + +YIK Sbjct 241 RAILVDSLAIALLNNNKITYEDFDFDEKSGGVFLNKKACEKFVEQFEKRLRQEVSYIKEV 300 Query 298 PHRYTFQYALDLQLQSLVRVIEAG 321 P++ +F+ ++ Q+ L++ EA Sbjct 301 PYKMSFRRIIEYQVMLLIKAFEAN 324 >gi|315925051|ref|ZP_07921268.1| conserved hypothetical protein [Pseudoramibacter alactolyticus ATCC 23263] gi|315621950|gb|EFV01914.1| conserved hypothetical protein [Pseudoramibacter alactolyticus ATCC 23263] Length=332 Score = 191 bits (485), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 109/324 (34%), Positives = 175/324 (55%), Gaps = 8/324 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYVS++ + I R++V +++ P+ETL+GITL +TT + +K+ Sbjct 1 MSLLYVSENGAVIQSQANRIVVNTKDGVSRSIPVETLEGITLLAPAQLTTQCMETCMKKG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQ--VHRTDDPAFCLSLSKRIVSRKILNQQAL 118 D+ F+ GHY GR++ A R+Q ++ +D F + LS+R+V+ K+ NQ + Sbjct 61 IDVVFFSKGGHYFGRLTATGYQKAGLQRRQAKLYHSD---FAIDLSRRMVAAKLNNQAVM 117 Query 119 IR--AHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAF 176 +R A DV + + ++ + ++ E+ G+EG+ AK+YF L V +FAF Sbjct 118 LRRYARNHAVDVNQEVMHIQWAKERAASERAIPEIMGYEGHGAKSYFKGLSRCVDSDFAF 177 Query 177 QGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEV 236 GRS RPP D FN+++SLGY++L + G IE H LN Y GF+HQD+ H TLASDLME Sbjct 178 SGRSRRPPRDPFNALISLGYAILLNELYGEIESHGLNPYFGFMHQDAEKHPTLASDLMEE 237 Query 237 WRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKG 296 WRA ++D + L+ + F ++ D G + T++ ++ + Y+ Sbjct 238 WRAVLVDSLAMSLLNGHELAVGDF-ESDDAGGCYLTKKGLAVFLNKMEKKMQTSIRYLHY 296 Query 297 DPHRYTFQYALDLQLQSLVRVIEA 320 + TF+ AL Q L + IEA Sbjct 297 LDYPVTFRRALGFQAGRLAKAIEA 320 >gi|121533432|ref|ZP_01665260.1| CRISPR-associated protein Cas1 [Thermosinus carboxydivorans Nor1] gi|121307991|gb|EAX48905.1| CRISPR-associated protein Cas1 [Thermosinus carboxydivorans Nor1] Length=332 Score = 189 bits (480), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 114/326 (35%), Positives = 165/326 (51%), Gaps = 6/326 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV+D+ S I GR +V + + P+E LD + LFG ++ I E LKR Sbjct 1 MRTLYVTDAGSHIQKNAGRFLVCKGDTILREIPLELLDNVVLFGSIQVSAKTITEFLKRG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 + + G + GR+ + RQQ+ D P FCL +++ I+ KI N ++R Sbjct 61 ITLTWLSKTGEFYGRLESTRHIDIFLHRQQIRMGDRPDFCLKIAQAIIDAKIANCMTILR 120 Query 121 AH---TSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 + + +VA+ I M + + L G EG+AA+ YFTAL LVP +FAF+ Sbjct 121 RYQRTANSPEVADHIHAMGIIAEKIPNVDKIETLLGLEGSAARHYFTALACLVPDDFAFK 180 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 GR+ +PP D FNS++S GY+LL + ++ L+ Y GFLH+D +GH TL SDLME W Sbjct 181 GRNKQPPKDPFNSLLSFGYTLLMYDFYTIVQNAGLHPYAGFLHKDRQGHPTLVSDLMEEW 240 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 R IID V+ LI + F G V+ REA+ A+ R+ R Y Sbjct 241 RPSIIDSLVMSLIHRREIQPLDFLPPDKNGGVYLNREASAEFIAAYEKRMTRLNKY---G 297 Query 298 PHRYTFQYALDLQLQSLVRVIEAGHP 323 TF+ L Q + L + IE P Sbjct 298 GKELTFRQLLARQAKLLSQAIENEDP 323 >gi|339890605|gb|EGQ79706.1| hypothetical protein HMPREF9094_1263 [Fusobacterium nucleatum subsp. animalis ATCC 51191] Length=335 Score = 186 bits (473), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 96/325 (30%), Positives = 169/325 (52%), Gaps = 3/325 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LY+ + + + + R+++ PIE +D + +FG ++T I + + Sbjct 1 MSNLYIYEQGIVLRYKENRLLITYTNGDYKSIPIENVDNVVIFGGIQLSTACIHNLPTKG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQAL-I 119 + + G Y GR+ + R R+Q ++DD FCL+L K+ + K NQ+ L I Sbjct 61 IHVTFLSKTGSYFGRLESTSNINIDRQREQFRKSDDKEFCLALGKKFIKGKATNQRTLLI 120 Query 120 RAHTSGQDVAES--IRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 RA+ ++ S I TM + ++ S ++ EL G EG AK YFT + H++ +++ F+ Sbjct 121 RANKDLKNTTLSNIIATMFGIIKNINDSKTIEELMGVEGYLAKVYFTGINHIIDKKYNFK 180 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 R+ RPP D FN+++S GY+LL+ I + LN Y FLH D H L SDLME W Sbjct 181 TRTKRPPKDPFNAVISFGYTLLHYEIFTTLVTKGLNPYAAFLHSDRHKHPALCSDLMEEW 240 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 RA ++D + L+ + + F + +G VF ++A F R+ + +YI Sbjct 241 RAILVDSMAIALLNNNKIAYEDFDFDEKSGGVFLNKKACGKFVEQFEKRLRQEVSYITEV 300 Query 298 PHRYTFQYALDLQLQSLVRVIEAGH 322 P++ +F+ ++ Q+ L++ +E+ + Sbjct 301 PYKMSFRRIVEYQIMLLIKALESNN 325 >gi|296133514|ref|YP_003640761.1| CRISPR-associated protein Cas1 [Thermincola sp. JR] gi|296032092|gb|ADG82860.1| CRISPR-associated protein Cas1 [Thermincola potens JR] Length=335 Score = 186 bits (471), Expect = 6e-45, Method: Compositional matrix adjust. Identities = 113/322 (36%), Positives = 171/322 (54%), Gaps = 3/322 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV + +R+ DGR+ ++ E P+E L+G+ L G MT VE+L++ Sbjct 1 MSFLYVCEPDTRVRIKDGRITAEQKDGMEVSIPLELLEGVVLMGSAQMTAACSVELLEKG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 + + G + GR+ + R R+Q DD FC + IV+ KI NQ ++R Sbjct 61 IPVTFLSRSGFFYGRLESTRHVNILRQRKQFRAGDDEEFCFKFTCMIVAAKIHNQAVILR 120 Query 121 A---HTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 H + V E I M+ + R+GS+A++ GFEG A+K YF AL +V + FAF Sbjct 121 RYNRHVNSPAVDECISRMQLLEENIARAGSIAQVMGFEGAASKHYFKALSLMVDRRFAFS 180 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 GR+ PPLD FNS++SLGY+LL A+ L+ Y G +H+D +GH LASDLME W Sbjct 181 GRNRMPPLDPFNSLLSLGYTLLLYETYTAVVNKGLHPYAGLMHRDRQGHPALASDLMEEW 240 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 R I+D V+ ++ G++ F K+ +GAV +A R + F +I A Y+ Sbjct 241 RPVIVDSLVMSIVQGGILAPGDFYKDEASGAVLLKNDALRKFIKHFEQKIRSEANYLSYL 300 Query 298 PHRYTFQYALDLQLQSLVRVIE 319 +R +++ A+ Q L IE Sbjct 301 DYRVSYRRAVQHQAGVLANCIE 322 >gi|121533442|ref|ZP_01665270.1| CRISPR-associated protein Cas1 [Thermosinus carboxydivorans Nor1] gi|121308001|gb|EAX48915.1| CRISPR-associated protein Cas1 [Thermosinus carboxydivorans Nor1] Length=332 Score = 185 bits (469), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 104/296 (36%), Positives = 156/296 (53%), Gaps = 3/296 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV+D+ S + + GR +V E P E LD + LFG +T I E LKR Sbjct 1 MRSLYVTDAGSHLQKSGGRFLVCKGEQILHAIPAEQLDNVVLFGSVQVTAKTITEFLKRG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 + ++ G + GR+ + + RQQ + FCL L+K I+ KI N ++R Sbjct 61 ITLTWLSSAGEFYGRLESTRHVDIHKQRQQFKMGERFDFCLKLAKSIIGAKIANCLTILR 120 Query 121 AH---TSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 + ++VA I +K L +D + ++ ++ G EG AA+ YF AL HLVP +F F Sbjct 121 RYQRTAQKEEVAHYIEVIKVYLDRIDSAETIEKVLGLEGIAARNYFQALSHLVPDDFHFS 180 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 GR+ +PP D FNS++S GY+LL ++ ++ L+ Y G +H+D +GH TL SDLME W Sbjct 181 GRNRQPPKDPFNSLLSFGYTLLMYDLYTIVQNAGLHPYAGLIHKDRQGHPTLVSDLMEEW 240 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATY 293 R IID V+ +I + F + G V+ REA S A+ R+ + Y Sbjct 241 RPTIIDALVMSVIQRREIQPCDFLPPDEKGGVYLCREAAASFIAAYEKRLTKLNKY 296 >gi|114567264|ref|YP_754418.1| hypothetical protein Swol_1749 [Syntrophomonas wolfei subsp. wolfei str. Goettingen] gi|114338199|gb|ABI69047.1| CRISPR-associated protein, Cas1 family [Syntrophomonas wolfei subsp. wolfei str. Goettingen] Length=336 Score = 181 bits (460), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 100/328 (31%), Positives = 175/328 (54%), Gaps = 4/328 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQ-YPIETLDGITLFGRPTMTTPFIVEMLKR 59 M LYV + ++I + V+V S++ + PIE ++ + +FG ++++ + + ++R Sbjct 1 MSFLYVYERSAKIGVQENCVVVESKKENLKRILPIEGVENVIIFGDASLSSNCVKQFMER 60 Query 60 ERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI 119 + ++ ++ G + GR+ + R R+Q +D FCL+L+KRI+ K+ NQ ++ Sbjct 61 DINLTWLSSRGKFYGRLESTRNVNIYRQRKQFACGEDDEFCLALAKRIILAKVKNQITIL 120 Query 120 RAHTSG---QDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAF 176 R + + V + I M L ++R + EL G EG AA+ Y+ L LV +FAF Sbjct 121 RRYRRNRPEKSVQKIIDAMAKLLPIMERVHNKDELMGHEGMAARYYYQGLAELVEPDFAF 180 Query 177 QGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEV 236 GR+ +PP D FNS++S Y+LL ++ A LN Y FLH RGH L SDLME Sbjct 181 SGRNRQPPRDPFNSLLSFAYTLLMYDLYTAAVNRGLNPYASFLHSIRRGHPALCSDLMEE 240 Query 237 WRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKG 296 WRA + D L + + G++ F K ++ G V+ +++ + ++ + Y+ Sbjct 241 WRAILADSLALYVTSKGIIKRENFEKPNEEGGVYLDGIGSKAFIAEYEKKVRGRSNYLAY 300 Query 297 DPHRYTFQYALDLQLQSLVRVIEAGHPS 324 + +F+ A+++Q Q L + IE G PS Sbjct 301 VDYSVSFRRAMEMQCQRLAKAIEEGDPS 328 >gi|237741581|ref|ZP_04572062.1| CRISPR-associated protein [Fusobacterium sp. 4_1_13] gi|229429229|gb|EEO39441.1| CRISPR-associated protein [Fusobacterium sp. 4_1_13] Length=335 Score = 181 bits (458), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 91/325 (28%), Positives = 170/325 (53%), Gaps = 3/325 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LY+ + + + + R+++ PIE +D + +FG ++T + +L + Sbjct 1 MSNLYIYEQGIVLRYKENRLLITYTNGDYKSIPIENIDNVVIFGGIQLSTACMHNLLIKG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQAL-I 119 + + G Y GR+ + R R+Q ++DD FCL++ K+ + K NQ+ L I Sbjct 61 IHVTFLSKTGSYFGRLESTSNINIDRQREQFRKSDDKKFCLAIGKKFIKGKATNQRTLLI 120 Query 120 RAHT--SGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 RA+ + ++ I +M + ++ S ++ EL G EG A+ YF A+ H++ ++++F+ Sbjct 121 RANKDLKSEILSSVINSMFGIIKDINDSKTIEELMGVEGYLARLYFNAINHIIDKKYSFK 180 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 R+ RPP D FN+++S GY+LL+ I + LN Y FLH D H L SDLME W Sbjct 181 TRTKRPPKDPFNAVISFGYTLLHYEIFTTLVTKGLNPYAAFLHSDRHKHPALCSDLMEEW 240 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 RA ++D + L+ + + F+ + +G VF ++A F R+ + +YI Sbjct 241 RAILVDSMAIALLNNNKIAYEDFNFDEKSGGVFLNKKACGKFVEQFEKRLRQEVSYITEV 300 Query 298 PHRYTFQYALDLQLQSLVRVIEAGH 322 ++ +F+ ++ Q+ L++ +E + Sbjct 301 SYKMSFRRIIEYQVMLLIKALENNN 325 >gi|258645680|ref|ZP_05733149.1| CRISPR-associated protein Cas1 [Dialister invisus DSM 15470] gi|260403048|gb|EEW96595.1| CRISPR-associated protein Cas1 [Dialister invisus DSM 15470] Length=331 Score = 177 bits (449), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 98/316 (32%), Positives = 171/316 (55%), Gaps = 7/316 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M +YV++ ++++ GR ++ E + P ++G+TLF +++ IV+ L+R Sbjct 1 MSWIYVTEPGAKLNRQGGRYVISRENETICEVPSAVVEGVTLFDSIQISSSVIVDFLERN 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 + ++ G + GR+ + D R ++Q D FCL+L+KR+V K+ NQ+ ++R Sbjct 61 IPLTWISSTGRFFGRLESTDHQNVLRQKEQFDALADKDFCLALAKRVVFGKVYNQRTILR 120 Query 121 AHTSGQD--VAESIRTMKHSLA-WVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 + + E +R+ LA + + S+ E+ G+EG A+ YF A+GH++P+EF F+ Sbjct 121 NYNRRAEDPFIEKVRSDIRILADKLHMAHSVEEVMGYEGMMARIYFQAIGHILPEEFRFE 180 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 R+ RPP D FNS++S GY+LL + AI L+ YIGFLH GH LASDLME W Sbjct 181 KRTKRPPRDYFNSLLSFGYTLLMYDFYSAIVNCGLHPYIGFLHALRNGHPALASDLMEPW 240 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 R ++D L L+ + F K + G ++ R R +A+ ++ Y +G Sbjct 241 RPAVVDAFCLSLVTHREISKDYFVK-GENGGIYLNRIGRRIFLQAYERKMRTVNRYFQGT 299 Query 298 PHRYTFQYALDLQLQS 313 Y++++ + ++ S Sbjct 300 ---YSWRHTIQMECDS 312 >gi|339278110|emb|CCC19858.1| CRISPR-associated protein cas1 [Streptococcus thermophilus JIM 8232] Length=334 Score = 176 bits (445), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 108/326 (34%), Positives = 171/326 (53%), Gaps = 4/326 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELG-ESQYPIETLDGITLFGRPTMTTPFIVEMLKR 59 M LY+ S +S ++ R+I+ ++ + I +D + LFG +TT I + K Sbjct 1 MSDLYIQRSNYYLSLSEQRIIIKNDNKEIVKEVSISLVDNVLLFGNAQLTTQLIKALSKN 60 Query 60 ERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI 119 + ++ F+ G + I T + Q + F L +++ I + K+ +Q AL+ Sbjct 61 KVNVYYFSNVGQFISSIETHRQDEFQKQELQAKAYFEEDFRLEVARSIATTKVRHQIALL 120 Query 120 RAH-TSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQG 178 R T G + S+ + ++ S+ E+ G+EG AK+YF L LVP +F F G Sbjct 121 REFDTDGLLDTSDYSRFEDSVNDIQKAYSITEIMGYEGRLAKSYFYYLNLLVPDDFHFNG 180 Query 179 RSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWR 238 RS RP D FNS ++ GYS+LY ++G I+++ L+ G +H+ + HATLASDLME WR Sbjct 181 RSRRPAEDCFNSALNFGYSILYSCLMGLIKKNGLSLGFGVIHKHHQHHATLASDLMEEWR 240 Query 239 APIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDP 298 I+D+T++ LI +G + F +N D + T E ARA +RI YI+ D Sbjct 241 PIIVDNTLMELIRNGKLLLSHF-ENKDQDFIL-TDEGREIFARALRSRILEVHQYIELDK 298 Query 299 HRYTFQYALDLQLQSLVRVIEAGHPS 324 RY+F Y D Q++SL+R PS Sbjct 299 KRYSFLYTADRQIKSLIRAFRELDPS 324 >gi|325695839|gb|EGD37730.1| hypothetical protein HMPREF9384_1727 [Streptococcus sanguinis SK160] Length=308 Score = 174 bits (440), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 100/310 (33%), Positives = 165/310 (54%), Gaps = 4/310 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQ-YPIETLDGITLFGRPTMTTPFIVEMLKR 59 M Y+ +S +S +D ++++ +++ + + +D I +FG ++T + + + Sbjct 1 MAFFYIQNSSYSLSISDRKLMIKNQDRTMLKAISLGLIDNILIFGNSQLSTQLLKSLSRH 60 Query 60 ERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI 119 + F++ G + + + + + R+Q + D +FCL +S+RI S KI+NQ L+ Sbjct 61 GIPVFYFSSKGEFLFSMDSFKEADYEKQREQAQSSFDKSFCLKMSQRIASAKIMNQLNLL 120 Query 120 RAHTS-GQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQG 178 +A+ + G E + K + + + S++E+ G EG AK+YF L LV ++F F Sbjct 121 KAYDAQGIFDEEDFKRFKAACESLKSAKSISEIMGIEGRIAKSYFYYLNLLVEEDFQFYC 180 Query 179 RSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWR 238 R+ RP LD FN++++ GYS+LY IG I ++ L+A G HQ HA LASDLME WR Sbjct 181 RNRRPSLDRFNALLNFGYSILYSCFIGLIRKNGLSAGFGVTHQPHTHHAVLASDLMEEWR 240 Query 239 APIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDP 298 I+DDTV+ LI G + F K D + T E +R RI Y++ D Sbjct 241 PVIVDDTVMSLIKHGDIRGEHFEKMGDE--MHLTSEGIEVFSRTMRERILEIHHYVELDK 298 Query 299 HRYTFQYALD 308 +RYTF Y D Sbjct 299 NRYTFLYMAD 308 >gi|294794257|ref|ZP_06759393.1| CRISPR-associated protein Cas1 [Veillonella sp. 3_1_44] gi|294454587|gb|EFG22960.1| CRISPR-associated protein Cas1 [Veillonella sp. 3_1_44] Length=331 Score = 170 bits (431), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 95/298 (32%), Positives = 161/298 (55%), Gaps = 6/298 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV+++ S I G V+V + P+E ++ IT+F ++T+ + + ++R Sbjct 1 MSSLYVTEAGSFIKRDGGHVVVGRNNEVLFEVPLERIEDITVFDSVSITSSLVTDFIERG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 I + G Y G I + + ++Q DD AF +++S++I+ K+ NQ ++R Sbjct 61 VPITWLSGYGKYFGTIINTNTIDINKHKKQFDLLDDNAFRVAMSRKIIRAKVRNQLTILR 120 Query 121 AHTSGQD----VAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAF 176 + + + I +K + + ++EL G+EG ++ YF ALG +VP FAF Sbjct 121 RYARNLEEDINIDVQIANIKSVRSHIGECMRVSELMGYEGLISRLYFEALGKIVPSAFAF 180 Query 177 QGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEV 236 R+ +PP D FN+M+ LGYS+L+ I+ + L+ ++G +H ++GH LASDL+E Sbjct 181 TKRTKQPPRDPFNAMLGLGYSMLFNEILAGVINAGLHPFVGVMHSLAKGHPALASDLIEE 240 Query 237 WRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYI 294 WRAPIID VL +++ +VD F NSD G + T E ++ A+ +I YI Sbjct 241 WRAPIIDSMVLSMVSRNMVDLSEFD-NSDKGC-YLTAEGRKAFLMAYNKKIRSENQYI 296 >gi|333976353|gb|EGL77222.1| CRISPR-associated endonuclease Cas1 [Veillonella parvula ACS-068-V-Sch12] Length=331 Score = 169 bits (429), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 95/298 (32%), Positives = 161/298 (55%), Gaps = 6/298 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV+++ S I G V+V + P+E ++ IT+F ++T+ + + ++R Sbjct 1 MSSLYVTEAGSFIKRDGGHVVVGRNNEVLFEVPLERIEDITVFDSVSITSSLVTDFIERG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 I + G Y G I + + ++Q DD AF +++S++I+ K+ NQ ++R Sbjct 61 VPITWLSGYGKYFGTIINTNTIDINKHKKQFDLLDDNAFRVAMSRKIIRAKVRNQLTILR 120 Query 121 AHTSGQD----VAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAF 176 + + + I +K + + ++EL G+EG ++ YF ALG +VP FAF Sbjct 121 RYARNLEEDINIDVQIANIKSVRSHIGECMRVSELMGYEGLISRLYFEALGKIVPPAFAF 180 Query 177 QGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEV 236 R+ +PP D FN+M+ LGYS+L+ I+ + L+ ++G +H ++GH LASDL+E Sbjct 181 TKRTKQPPRDPFNAMLGLGYSMLFNEILAGVINAGLHPFVGVMHSLAKGHPALASDLIEE 240 Query 237 WRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYI 294 WRAPIID VL +++ +VD F NSD G + T E ++ A+ +I YI Sbjct 241 WRAPIIDSMVLSMVSRNMVDLSEFD-NSDKGC-YLTAEGRKAFLMAYNKKIRSENQYI 296 >gi|238018273|ref|ZP_04598699.1| hypothetical protein VEIDISOL_00097 [Veillonella dispar ATCC 17748] gi|237864744|gb|EEP66034.1| hypothetical protein VEIDISOL_00097 [Veillonella dispar ATCC 17748] Length=331 Score = 168 bits (426), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 94/298 (32%), Positives = 160/298 (54%), Gaps = 6/298 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV+++ S I G V+V + P+E ++ IT+F ++T+ + + ++R Sbjct 1 MSSLYVTEAGSFIKRDGGHVVVGRNNEVLFEVPLERIEDITVFDSVSITSSLVTDFIERG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 I + G Y G + + + ++Q DD AF +++S++I+ K+ NQ ++R Sbjct 61 VPITWLSGYGKYFGTLINTNTIDINKHKKQFDLLDDNAFRVAMSRKIIRAKVRNQLTILR 120 Query 121 AHTSGQD----VAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAF 176 + + + I +K + + ++EL G+EG ++ YF ALG +VP FAF Sbjct 121 RYARNLEEDINIDAQIANIKSVRSHIGECMRVSELMGYEGLISRLYFEALGKIVPSAFAF 180 Query 177 QGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEV 236 R+ +PP D FN+M+ LGYS+L+ I+ + L+ ++G +H ++GH LASDL+E Sbjct 181 TKRTKQPPRDPFNAMLGLGYSMLFNEILAGVINAGLHPFVGIMHSLAKGHPALASDLIEE 240 Query 237 WRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYI 294 WRAPIID VL +++ +VD F NSD G + T E + A+ +I YI Sbjct 241 WRAPIIDSMVLSMVSRNMVDLAEFD-NSDKGC-YLTAEGRKVFLTAYNKKIRSENQYI 296 >gi|116627764|ref|YP_820383.1| hypothetical protein STER_0970 [Streptococcus thermophilus LMD-9] gi|116101041|gb|ABJ66187.1| CRISPR-associated protein, Cas1 family [Streptococcus thermophilus LMD-9] Length=334 Score = 167 bits (422), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 106/326 (33%), Positives = 168/326 (52%), Gaps = 4/326 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELG-ESQYPIETLDGITLFGRPTMTTPFIVEMLKR 59 M LY S +S ++ R+I+ ++ + I +D + LFG +TT I + K Sbjct 1 MSDLYSQRSNYYLSLSEQRIIIKNDNKEIVKEVSISLVDNVLLFGNAQLTTQLIKALSKN 60 Query 60 ERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI 119 + ++ F+ G + I T + Q + F L +++ I + K+ +Q AL+ Sbjct 61 KVNVYYFSNVGQFISSIETHRQDEFQKQELQAKAYFEEDFRLEVARSIATTKVRHQIALL 120 Query 120 RAH-TSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQG 178 R T G + S+ + ++ S+ E+ G+EG AK+YF L LVP +F F G Sbjct 121 REFDTDGLLDTSDYSRFEDSVNDIQKAYSITEIMGYEGRLAKSYFYYLNLLVPDDFHFNG 180 Query 179 RSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWR 238 RS R D FNS ++ GYS+LY ++G I+++ L+ G +H+ + HATLASDLME WR Sbjct 181 RSRRTAEDCFNSALNFGYSILYSCLMGLIKKNGLSLGFGVIHKHHQHHATLASDLMEEWR 240 Query 239 APIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDP 298 I+D+T++ LI +G + F +N D + T E A A +RI YI+ D Sbjct 241 PIIVDNTLMELIRNGKLLLSHF-ENKDQDFIL-TDEGREIFAWALRSRILEVHRYIELDK 298 Query 299 HRYTFQYALDLQLQSLVRVIEAGHPS 324 RY+F Y D Q++SL+R PS Sbjct 299 KRYSFLYTADRQIKSLIRAFRELDPS 324 >gi|303231960|ref|ZP_07318668.1| CRISPR-associated endonuclease Cas1 [Veillonella atypica ACS-049-V-Sch6] gi|302513389|gb|EFL55423.1| CRISPR-associated endonuclease Cas1 [Veillonella atypica ACS-049-V-Sch6] Length=331 Score = 166 bits (421), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 97/298 (33%), Positives = 159/298 (54%), Gaps = 6/298 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV++S S I G V+V + P+E ++ IT+F ++T+ + + ++R Sbjct 1 MSSLYVTESGSFIKRNGGHVVVGRNNEVLFEVPLERIEDITVFDTVSITSSLVTDFIERG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 I + G Y G I + + ++Q D+ F L++S++I+ K+ NQ ++R Sbjct 61 IPITWLSGYGKYFGTIINTNTIDINKHKKQFDLLDNHEFRLAISRKIIRAKVRNQLTILR 120 Query 121 AHTSGQDVAESIRT----MKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAF 176 + D SI T +K + + ++EL G+EG ++ YF ALG +VP F+F Sbjct 121 RYARNLDEDISIDTQIDNIKSVRSHIGECVRISELMGYEGIISRLYFEALGKIVPPIFSF 180 Query 177 QGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEV 236 RS +PP D FN+M+ LGYS+L+ I+ + L+ ++G +H +GH LASDL+E Sbjct 181 TKRSKQPPRDEFNAMLGLGYSMLFNEILAGLINAGLHPFVGVMHSLGKGHPALASDLIEE 240 Query 237 WRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYI 294 WRAPIID VL +++ +V+ F NSD G + T E + A+ +I YI Sbjct 241 WRAPIIDSMVLSMVSRNMVELSDFD-NSDKGC-YLTTEGRKGFLVAYNKKIRSENQYI 296 >gi|342214546|ref|ZP_08707233.1| CRISPR-associated endonuclease Cas1 [Veillonella sp. oral taxon 780 str. F0422] gi|341592059|gb|EGS34954.1| CRISPR-associated endonuclease Cas1 [Veillonella sp. oral taxon 780 str. F0422] Length=331 Score = 164 bits (416), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 92/297 (31%), Positives = 151/297 (51%), Gaps = 4/297 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV++S S I G VIV + P E++D +T+F +++ + + + Sbjct 1 MTTLYVTESGSFIKRKGGHVIVGRNHEVLFEVPFESIDDVTVFDSVHISSSLLTDFISNG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 + + G Y G + + + ++Q D FCL+LSK++++ KI NQ ++R Sbjct 61 IPVTWLSGYGKYFGTLINTNTVDIHKHQRQFTIRGDKEFCLALSKKLINAKINNQLTILR 120 Query 121 AHTSG---QDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 + V SI + H + ++ S+ EL G+EG ++ YF LG +VP EF F Sbjct 121 RYERNLLDDSVMMSINNICHIRKNIHKATSIEELMGYEGIISRLYFEGLGKIVPFEFTFT 180 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 RS +PPLD FN+M+ LGYS+L+ I+ + L+ ++G +H GH L SDL+E W Sbjct 181 KRSKQPPLDPFNAMLGLGYSMLFNEIMAGVINAGLHPFVGCMHSIKGGHPALVSDLIEEW 240 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYI 294 RAP+ID VL L+ ++D + S G + E + A+ +I Y+ Sbjct 241 RAPVIDSLVLNLVKRKMIDVEEDFQYSGEGC-YLNGEGRKLFLSAYNKKIKSMNQYM 296 >gi|341822659|emb|CCC73583.1| CRISPR-associated endonuclease CaS1 [Megasphaera elsdenii DSM 20460] Length=331 Score = 163 bits (413), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 98/323 (31%), Positives = 162/323 (51%), Gaps = 7/323 (2%) Query 5 YVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQ 64 Y+++ + IS DGR +V + P ETL+G+ + +T+ IV +L + Sbjct 5 YITEKGATISKKDGRFVVGRNHETLLEIPEETLEGLLVTDTVQLTSHAIVSLLHLGIPVT 64 Query 65 LFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHTS 124 ++ G Y GR+ + + +QQ D P F L +S+R++ K+ NQ L+R + Sbjct 65 WLSSHGKYFGRLESTRHVSVFKQKQQFLLQDQP-FSLEMSRRVLLAKVHNQLTLLRRYNR 123 Query 125 GQDVAESIRTMKHSLAWVDR---SGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRST 181 + + + + + + D + L G+EG AAK YF+ALG LV FAF+ RS Sbjct 124 DRKIPSVMIDIHNMMTMADHLKIAEDCESLMGYEGMAAKIYFSALGKLVDPTFAFEKRSK 183 Query 182 RPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAPI 241 RPPLD FNS++S Y+L+ + AI L+ Y+GFLH H LASDL+E WRA + Sbjct 184 RPPLDPFNSLLSFAYTLIMYELFTAITNEGLHPYVGFLHTLKEHHPALASDLLEEWRAVL 243 Query 242 IDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGDPHRY 301 D V+ L+ + F + ++ T E + RA+ ++ YI G ++ Sbjct 244 ADSFVMSLVQHHEIKEEHFCCDEANHGIYLTPEGRKIFFRAYEKKMRSINQYIDG---KH 300 Query 302 TFQYALDLQLQSLVRVIEAGHPS 324 +F+ +L+ Q+ + + A P Sbjct 301 SFRRSLNYQVAQYGQALMAREPK 323 >gi|159899002|ref|YP_001545249.1| CRISPR-associated Cas1 family protein [Herpetosiphon aurantiacus DSM 785] gi|159892041|gb|ABX05121.1| CRISPR-associated protein Cas1 [Herpetosiphon aurantiacus DSM 785] Length=339 Score = 161 bits (407), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 96/330 (30%), Positives = 161/330 (49%), Gaps = 9/330 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV + + I R+ +W + P+ L+ I + G +TP I +L ++ Sbjct 1 MATLYVLEQGAEIRCDGERLAIWQTDQELGNVPMAKLEDIVVMGNIGFSTPAIKRLLDQQ 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 ++ T G Y GR+ ++ R Q R DD + L++++ VS K+ N +A+++ Sbjct 61 IEVTFLTIHGRYHGRLIGEATAHVALRRNQYRRADDEVWALAMAQACVSGKLRNCRAVLQ 120 Query 121 AHTSG-----QDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFA 175 ++V ESI + H + VDR+ ++ L G EG+ + AYF L L E+ Sbjct 121 RFARNRQQVEKEVLESIEALDHFIDRVDRTTKISSLVGVEGSGSAAYFGGLRGLFDSEWM 180 Query 176 FQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLME 235 F R+ RPP D N ++SLGY+LL +GA++ + Y GFLHQ +L DL+E Sbjct 181 FNNRNRRPPTDPVNVLLSLGYTLLVHKTLGAVQAVGFDPYQGFLHQLDYNRPSLVLDLIE 240 Query 236 VWRAPIIDDTVLRLIADGVVDTRAFSKNSDTG-AVFATREATRSIARAFGNRIARTATY- 293 +R ++D V+R DG + FS + D + + E + AF R+ T+ Sbjct 241 EFRPILVDALVIRCCNDGRLTANDFSPSDDPKHPILLSNEGKKRFVVAFEERMRTEVTHP 300 Query 294 --IKGDPHRYTFQYALDLQLQSLVRVIEAG 321 G P + ++ ++LQ + L R I+ G Sbjct 301 DGADGRPGKVSYWRCIELQARLLARAIQTG 330 >gi|291539925|emb|CBL13036.1| CRISPR-associated protein Cas1 [Roseburia intestinalis XB6B4] Length=232 Score = 159 bits (402), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 81/219 (37%), Positives = 123/219 (57%), Gaps = 2/219 (0%) Query 103 LSKRIVSRKILNQQALIRAHTSG--QDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAK 160 +SKRI+ KI NQ ++R + G +D+ I M++ + + S+ ++ G+EG AAK Sbjct 1 MSKRIIDAKIRNQVVVLRRYARGRDEDIHRMIIEMQNMQKKLLYAKSVEQVMGYEGTAAK 60 Query 161 AYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLH 220 YF LG L+ ++F F+GRS RPP+D FNS++SLGYS++ + G IE LN Y G +H Sbjct 61 IYFKVLGKLIDEQFVFEGRSRRPPMDPFNSLISLGYSIILNELYGKIEGKGLNPYFGVMH 120 Query 221 QDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIA 280 +D H TLASDLME WRA +ID T L ++ + F D VF ++ R Sbjct 121 KDREKHPTLASDLMEEWRAVLIDTTALSMLNGHELVKEDFYTGIDQPGVFLEKDGFRKYI 180 Query 281 RAFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIE 319 + + Y+ + +F+ A+DLQ+ V+ IE Sbjct 181 QKLEGKFRTENKYLSYIDYSVSFRRAMDLQVNQFVKAIE 219 >gi|125718075|ref|YP_001035208.1| hypothetical protein SSA_1255 [Streptococcus sanguinis SK36] gi|125497992|gb|ABN44658.1| Conserved hypothetical protein [Streptococcus sanguinis SK36] Length=262 Score = 159 bits (402), Expect = 7e-37, Method: Compositional matrix adjust. Identities = 88/262 (34%), Positives = 146/262 (56%), Gaps = 2/262 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQ-YPIETLDGITLFGRPTMTTPFIVEMLKR 59 M LY+ +S +S +D ++++ ++E + + +D I +FG ++T + + + Sbjct 1 MADLYIQNSSYSLSISDRKLMIKNQERTMLKAISLGLIDNILIFGNSQLSTQLLKSLSRH 60 Query 60 ERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI 119 + F++ G + + + + + R+Q + D +FCL +SKRI S KI+NQ L+ Sbjct 61 GIPVFYFSSKGEFLFSMDSFKEADYEKQREQAQASFDKSFCLKMSKRIASAKIMNQLNLL 120 Query 120 RAH-TSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQG 178 +A+ G E + K + ++ + S++E+ G EG AK+YF L LV ++F F Sbjct 121 KAYDEQGLFDEEDFKRFKSACESLESAKSISEIMGIEGRIAKSYFYYLNLLVEEDFQFYS 180 Query 179 RSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWR 238 R+ P LD FN++++ GYS+LY IG I ++ L+A G HQ HA LASDLME WR Sbjct 181 RNRSPSLDRFNALLNFGYSILYSCFIGLIRKNGLSAGFGVTHQPHTHHAVLASDLMEEWR 240 Query 239 APIIDDTVLRLIADGVVDTRAF 260 I+DDTV+ LI G + AF Sbjct 241 PVIVDDTVMSLIKHGDIRGGAF 262 >gi|327470946|gb|EGF16402.1| CRISPR-associated protein cas1 [Streptococcus sanguinis SK330] Length=230 Score = 158 bits (399), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 86/219 (40%), Positives = 126/219 (58%), Gaps = 3/219 (1%) Query 103 LSKRIVSRKILNQQALIRAH-TSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKA 161 +S+RI S KI+NQ L++AH G E + K + ++ + S++E+ G EG AK+ Sbjct 1 MSQRIASAKIMNQLNLLKAHDEQGLFDEEDFKRFKAACESLESAKSISEIIGIEGRIAKS 60 Query 162 YFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQ 221 YF L LV ++F F R+ RP LD FN++++ GY +LY IG I ++ L+A G HQ Sbjct 61 YFYYLNLLVKEDFQFYCRNRRPSLDRFNALLNFGYLILYSCFIGLIRKNGLSAGFGVTHQ 120 Query 222 DSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIAR 281 HA LASDLME WR I+DDTV+ LI G + F KN + + T + +R Sbjct 121 PHTHHAVLASDLMEEWRPVIVDDTVMSLIKQGDIRGEHFEKNGEE--MHLTSKGIEVFSR 178 Query 282 AFGNRIARTATYIKGDPHRYTFQYALDLQLQSLVRVIEA 320 A RI Y++ D +RYTF Y D Q++SL+R ++ Sbjct 179 AMRERILEIHHYVELDKNRYTFLYIADQQVKSLIRCFKS 217 >gi|323141545|ref|ZP_08076431.1| CRISPR-associated endonuclease Cas1 [Phascolarctobacterium sp. YIT 12067] gi|322414004|gb|EFY04837.1| CRISPR-associated endonuclease Cas1 [Phascolarctobacterium sp. YIT 12067] Length=330 Score = 154 bits (390), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 92/321 (29%), Positives = 161/321 (51%), Gaps = 8/321 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LY+++S + + G V+V + P+E ++ +TL +++ I E L+R Sbjct 1 MTSLYITESGAYLRKRGGHVLVGRNNEVLLEVPLERIEDVTLVDSVQISSGLITEFLERN 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 + + G + G + + + ++Q + L+K+I+ K+ NQ ++R Sbjct 61 IPLSWLSGRGRFFGSLLSNGSIDIIKHQKQFELLQEGKLYFELAKKIIYAKVHNQLTILR 120 Query 121 AHTSG---QDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 + +V SIR + + ++ L L GFEG ++ YF ALG +VP EF F+ Sbjct 121 RYNRNLKLDNVDTSIRNILAIRKNICQTDDLHSLMGFEGIISRIYFCALGAIVPDEFKFE 180 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 R+ PP D FNSM+SLGYS+L+ I+ + L+ Y+GF+H+ ++GH L SDL+E W Sbjct 181 KRTKMPPRDPFNSMLSLGYSMLFNEIMSNVLALGLHPYVGFMHKIAKGHPALVSDLIEEW 240 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 RAP+ID VL +I ++ F N F EA + + + ++ Y + Sbjct 241 RAPLIDSMVLAMIKRNMLTRDMFEINE--AGCFLNTEARKIYLQTYNKKLRSDNQYFED- 297 Query 298 PHRYTFQYALDLQLQSLVRVI 318 +YT++ ++ Q + VI Sbjct 298 --KYTYRESIRQQCRKYASVI 316 >gi|309791951|ref|ZP_07686429.1| CRISPR-associated Cas1 family protein [Oscillochloris trichoides DG6] gi|308225945|gb|EFO79695.1| CRISPR-associated Cas1 family protein [Oscillochloris trichoides DG6] Length=339 Score = 154 bits (388), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 109/333 (33%), Positives = 167/333 (51%), Gaps = 11/333 (3%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV + + I R++V + PI LD I + G ++TP + + +R Sbjct 1 MATLYVIEQGAEIGCDGERIVVRRQGQEIGSVPISRLDDILIIGNIGISTPALKRLFERG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI- 119 ++ T G YQGR+ +A R Q R DDPA+ LS ++ V+ K+ N + L+ Sbjct 61 IEVTFLTVHGRYQGRLVGATTPHAALRRAQYRRADDPAWSLSQAQACVTGKLRNARVLLQ 120 Query 120 -----RAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEF 174 R++ S DV+ + + +A ++R+ L+ L G EG+A YF L L ++ Sbjct 121 RFARNRSNVS-PDVSIAADDLSTYIARIERTTQLSSLLGVEGSATARYFGGLRALFEPDW 179 Query 175 AFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLM 234 F RS RPP D N ++SLGY+LL + AI L+ Y+G+LHQ G A+LA D+M Sbjct 180 QFHARSRRPPGDPVNVLLSLGYTLLLHKVTAAIAASGLDPYMGYLHQIEYGRASLALDMM 239 Query 235 EVWRAPIIDDTVLRLIADGVVDTRAF-SKNSDTGAVFATREATRSIARAFGNRIARTATY 293 E +R ++D VLR DG V F S A+ + E R AF R+ AT+ Sbjct 240 EEFRPLLVDSLVLRCCGDGRVQAEDFRSGGEGERAIVFSPEGQRRFISAFEERMRTEATH 299 Query 294 IKG---DPHRYTFQYALDLQLQSLVRVIEAGHP 323 +G P + ++ L+LQ + LVR I+ P Sbjct 300 PEGADSGPGKVSYMRCLELQARRLVRAIQGSTP 332 >gi|334126733|ref|ZP_08500681.1| CRISPR-associated protein Cas1 [Centipeda periodontii DSM 2778] gi|333391143|gb|EGK62264.1| CRISPR-associated protein Cas1 [Centipeda periodontii DSM 2778] Length=331 Score = 154 bits (388), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 98/317 (31%), Positives = 161/317 (51%), Gaps = 8/317 (2%) Query 5 YVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDIQ 64 Y+++ + + G ++ + P E L+ +TL +++ +VE+L+ + Sbjct 4 YITEEGAYVQKRGGNFVIGRNNECVMEIPEEVLESLTLIDSVQVSSQAMVELLRLGVPVT 63 Query 65 LFTTDGHYQGRI-STPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHT 123 + G + GR+ ST V+ + RQ + + F L + +++++ K+ NQ L+R + Sbjct 64 WLSRTGFFFGRLESTRHVNVFRQERQVLMKGS--GFYLRMGRKVIAAKVHNQLTLLRRYN 121 Query 124 SGQDVAESIRTMKHSLAWVDR---SGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQGRS 180 ++ + + LA R + + +L G+EG AK YF ALG LVP+EFAF RS Sbjct 122 RNAELPGVQQAIDEILALRKRIPLAETSEQLMGYEGAIAKVYFRALGLLVPEEFAFMRRS 181 Query 181 TRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRAP 240 RPPLD FN+M+S GY+LL +I A+ L+ Y GFLH H LASDLME WRA Sbjct 182 KRPPLDPFNAMLSFGYTLLMYDIYTALSNEGLHPYFGFLHALKNRHPALASDLMEEWRAV 241 Query 241 IIDDTVLRLIADGVVDTRAFSK-NSDTGAVFATREATRSIARAFGNRIARTATYIKGD-P 298 ++D VL L++ + F+ D + TRE RA+ ++ Y++G Sbjct 242 LVDAMVLSLVSHHEIKREHFAAMKEDEPGIILTREGRAIFLRAYEKKLRTANRYVEGKHS 301 Query 299 HRYTFQYALDLQLQSLV 315 +R T Y Q+L+ Sbjct 302 YRRTLAYQARQYAQALL 318 >gi|313894905|ref|ZP_07828465.1| CRISPR-associated endonuclease Cas1 [Selenomonas sp. oral taxon 137 str. F0430] gi|312976586|gb|EFR42041.1| CRISPR-associated endonuclease Cas1 [Selenomonas sp. oral taxon 137 str. F0430] Length=333 Score = 154 bits (388), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 93/330 (29%), Positives = 166/330 (51%), Gaps = 11/330 (3%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M +Y++D +++ + +V + P E ++G+ L +++ +VE+LK Sbjct 1 MSFIYITDEGAKLQKKGDKFLVGRNLEILMEIPKEIIEGLVLIDSVQISSDAVVELLKLG 60 Query 61 RDIQLFTTDGHYQGRI-STPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI 119 +T G + GR+ ST +V + RQ + + + F + L K+I + K+ NQ L+ Sbjct 61 VPTTWISTHGKFYGRLESTRNVDVFKQRRQIL--SQESEFAVKLCKKIAAAKVHNQLTLL 118 Query 120 RAHT-----SGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEF 174 R + +++A + ++ +D ++ G+EG +A+ YF ALG + P F Sbjct 119 RRYNRREEEHAKEIASLVTRLQILQKNIDFVSEKEKIMGYEGASARHYFKALGMMTPSPF 178 Query 175 AFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLM 234 +F+ R+ +PP DAFNSM+S GY+LL I A+ L+ Y GF H H LASDLM Sbjct 179 SFERRTRQPPRDAFNSMLSFGYTLLMYEIYTALCNQGLSPYFGFFHALKNRHPALASDLM 238 Query 235 EVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYI 294 E WR +ID V+ L+ V F ++ + V+ TRE RA+ ++ Y+ Sbjct 239 EEWRPVLIDSMVMSLVHHHEVQPEHFMRSEENDGVYMTREGRTIFLRAYEKKLRTMNRYL 298 Query 295 KGDPHRYTFQYALDLQLQSLVRVIEAGHPS 324 G+ ++++ +L +Q + + + A P Sbjct 299 TGE---HSYRKSLTIQAKKFSQALMAEEPE 325 >gi|327474433|gb|EGF19839.1| hypothetical protein HMPREF9391_0559 [Streptococcus sanguinis SK408] Length=242 Score = 152 bits (384), Expect = 8e-35, Method: Compositional matrix adjust. Identities = 81/225 (36%), Positives = 127/225 (57%), Gaps = 1/225 (0%) Query 37 LDGITLFGRPTMTTPFIVEMLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDD 96 +D I +FG ++T + + + + F++ G + + + + + R+Q + D Sbjct 18 IDNILIFGNSQLSTQLLKSLSRHGIPVFYFSSKGEFLFSMDSFKEADYEKQREQAQASFD 77 Query 97 PAFCLSLSKRIVSRKILNQQALIRAH-TSGQDVAESIRTMKHSLAWVDRSGSLAELNGFE 155 +FCL +SKRI S KI+NQ L++A+ G E + K + ++ + S++E+ G E Sbjct 78 KSFCLKMSKRIASAKIMNQLNLLKAYDEQGLFDEEDFKRFKSACESLESAKSISEIMGIE 137 Query 156 GNAAKAYFTALGHLVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAY 215 G AK+YF L LV ++F F R+ P LD FN++++ GYS+LY IG I ++ L+A Sbjct 138 GRIAKSYFYYLNLLVEEDFQFYSRNRSPSLDRFNALLNFGYSILYSCFIGLIRKNGLSAG 197 Query 216 IGFLHQDSRGHATLASDLMEVWRAPIIDDTVLRLIADGVVDTRAF 260 G HQ HA LASDLME WR I+DDTV+ LI G + AF Sbjct 198 FGVTHQPHTHHAVLASDLMEEWRPVIVDDTVMSLIKHGDIRGGAF 242 >gi|209526394|ref|ZP_03274922.1| CRISPR-associated protein Cas1 [Arthrospira maxima CS-328] gi|209493167|gb|EDZ93494.1| CRISPR-associated protein Cas1 [Arthrospira maxima CS-328] Length=654 Score = 151 bits (382), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 96/316 (31%), Positives = 157/316 (50%), Gaps = 8/316 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV+D + + + V + P+ +D I LFG ++ I L+R Sbjct 320 MTTLYVTDQGAYVKVKHQQFQVLLGNDLKVSIPVNVVDYIILFGCCNLSHGAIGLALRRR 379 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 I + G Y GR+ T ++ L +QVH +D F L +K IV+ K+ N + L+R Sbjct 380 IPILFLSYQGRYFGRLQTDGMTRVDYLSRQVHCAEDETFVLRQAKVIVAGKLHNCRILLR 439 Query 121 AHTSGQDVAESIRTMKHSLAWVDRSGS---LAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 + +++ I ++ W ++ L L G+EG + YF ALG LV F F+ Sbjct 440 RLNRDRQISQVIEAIEELGVWQEKIAEVELLESLLGYEGFGTRIYFQALGALVQPPFTFE 499 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 R+ RPP D NS++SLGY+LL++NI I L+ + G LH H L SDL+E + Sbjct 500 HRTRRPPTDPVNSLLSLGYTLLHQNIHSLILAVGLHPHYGNLHVPRSNHPALVSDLIEEF 559 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 RAP++D V+ L+ G+ F+ + + G V+ +A + + + ++++ T+ Sbjct 560 RAPVVDSLVIYLVNSGIFTPEDFTPSDERGGVYLYSDALKKYLKHWQDKLSLKTTH---- 615 Query 298 PHR-YTFQYALDLQLQ 312 PH Y Y L+LQ Sbjct 616 PHTGYKVSYYRCLELQ 631 >gi|156741961|ref|YP_001432090.1| CRISPR-associated Cas1 family protein [Roseiflexus castenholzii DSM 13941] gi|156233289|gb|ABU58072.1| CRISPR-associated protein Cas1 [Roseiflexus castenholzii DSM 13941] Length=339 Score = 151 bits (381), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 97/330 (30%), Positives = 161/330 (49%), Gaps = 9/330 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV++ S I R+ V + + P+ ++ I + G ++TP I ML Sbjct 1 MDTLYVTEQGSEIGCDGERLAVRRDNAIIASIPLIKIEDIVIIGNVGLSTPAIKRMLDNG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 ++ T G YQGR+ ++A Q R DD A+ L L++R V K+ N +AL+R Sbjct 61 INVTFLTVHGRYQGRLVGSVSAHAALRAAQYRRADDRAWSLRLAQRFVEGKLRNCRALLR 120 Query 121 AHTSGQ-----DVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFA 175 + + ++ + + V R+ +L L G EG+A YF + L+ E+ Sbjct 121 RFARNRADAPAEAGQAADDLDRFIDRVPRTTTLNALMGVEGSATARYFAGVRALIGAEWR 180 Query 176 FQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLME 235 F+ R RPP D N+++S GY+LL ++GA+E + Y+G+LH G +LA DL+E Sbjct 181 FEARIRRPPPDRVNALLSFGYTLLVHKMLGAVEAAGFDPYLGYLHHIDYGRPSLALDLIE 240 Query 236 VWRAPIIDDTVLRLIADGVVDTRAFSKNSDTG-AVFATREATRSIARAFGNRIARTATY- 293 +R ++D V+R DG + F++ D V + + R AF R+ AT+ Sbjct 241 EFRPILVDSLVIRCCNDGRIAFDDFTETPDGDYPVLLSDDGKRRFVAAFEERMRTEATHP 300 Query 294 --IKGDPHRYTFQYALDLQLQSLVRVIEAG 321 G P + ++ L LQ + L R ++ G Sbjct 301 DGADGRPGKVSYLRCLALQARRLARAVQGG 330 >gi|163846146|ref|YP_001634190.1| CRISPR-associated Cas1 family protein [Chloroflexus aurantiacus J-10-fl] gi|222523888|ref|YP_002568358.1| CRISPR-associated protein Cas1 [Chloroflexus sp. Y-400-fl] gi|163667435|gb|ABY33801.1| CRISPR-associated protein Cas1 [Chloroflexus aurantiacus J-10-fl] gi|222447767|gb|ACM52033.1| CRISPR-associated protein Cas1 [Chloroflexus sp. Y-400-fl] Length=339 Score = 150 bits (380), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 99/326 (31%), Positives = 155/326 (48%), Gaps = 8/326 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LY+ + + I R++V P+ +D I +FG ++TP I +L R Sbjct 1 MATLYLIEQGAEIGCDGERIVVRRAGEIIGSVPLVKVDDIVIFGNIGISTPAIKRLLDRS 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 ++ T DG YQGR+ ++ + Q D L L++ V K+ NQ+AL++ Sbjct 61 IEVTFMTVDGSYQGRLVGQVTAHVALRQAQYACAADSDRTLRLAQSFVEGKLRNQRALLQ 120 Query 121 AHTSGQDVAESIRTMKHS-----LAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFA 175 + + + + V R+ L+ L G EG+A YF L L+ E+ Sbjct 121 RFSRNRATPPAEALAAADDLDAYIKRVRRTTRLSALLGVEGSATARYFAGLRSLIEPEWD 180 Query 176 FQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLME 235 F+ R RPP D N ++S GY+LL +GA++ + Y+GFLH G +LA DLME Sbjct 181 FRSRQRRPPPDPVNLLLSFGYTLLTHKTLGAVQAAGFDPYLGFLHSLDYGRPSLALDLME 240 Query 236 VWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIK 295 +R +ID V+R+ DG + F + V T E R+ AF R+ AT+ + Sbjct 241 EFRPLLIDSLVVRVCNDGRLRLEHFQPGDEARPVIITDEGKRAFLTAFEERMRTEATHPE 300 Query 296 G---DPHRYTFQYALDLQLQSLVRVI 318 G P + T+Q + LQ + L RVI Sbjct 301 GADSGPGKVTYQRCIALQARRLARVI 326 >gi|291568436|dbj|BAI90708.1| CRISPR-associated protein Cas1 [Arthrospira platensis NIES-39] Length=599 Score = 148 bits (374), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 95/316 (31%), Positives = 156/316 (50%), Gaps = 8/316 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV+D + + + V + P+ +D I LFG ++ I L+R Sbjct 266 MTTLYVTDQGAYVKVKHQQFQVLLGNDLKVSIPVNVVDYIILFGCCNLSHGAIGLALRRR 325 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 I + G Y GR+ T ++ L +QVH +D F L +K IV+ K+ N + L+R Sbjct 326 IPILFLSDQGRYFGRLQTDGMTRVDYLSRQVHCAEDETFVLRQAKVIVAGKLHNCRILLR 385 Query 121 AHTSGQDVAESIRTMKHSLAWVDRSGS---LAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 + +++ I ++ W ++ L L G+EG + YF AL LV F F+ Sbjct 386 RLNRDRQISQVIEAIEELGVWQEKIAEVELLESLLGYEGFGTRIYFQALRALVQPPFTFE 445 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 R+ RPP D NS++SLGY+LL++NI I L+ + G LH H L SDL+E + Sbjct 446 HRTRRPPTDPVNSLLSLGYTLLHQNIHSLILAVGLHPHYGNLHVPRSNHPALVSDLIEEF 505 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 RAP++D V+ L+ G+ F+ + + G V+ +A + + + ++++ T+ Sbjct 506 RAPVVDSLVIYLVNSGIFTPEDFTPSDERGGVYIYSDALKKYLKHWHDKLSLKTTH---- 561 Query 298 PHR-YTFQYALDLQLQ 312 PH Y Y L+LQ Sbjct 562 PHTGYKVSYYRCLELQ 577 >gi|284052685|ref|ZP_06382895.1| hypothetical protein AplaP_14548 [Arthrospira platensis str. Paraca] Length=592 Score = 148 bits (374), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 95/316 (31%), Positives = 156/316 (50%), Gaps = 8/316 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV+D + + + V + P+ +D I LFG ++ I L+R Sbjct 259 MTTLYVTDQGAYVKVKHQQFQVLLGNDLKVSIPVNVVDYIILFGCCNLSHGAIGLALRRR 318 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 I + G Y GR+ T ++ L +QVH +D F L +K IV+ K+ N + L+R Sbjct 319 IPILFLSDQGRYFGRLQTDGMTRVDYLSRQVHCAEDETFVLRQAKVIVAGKLHNCRILLR 378 Query 121 AHTSGQDVAESIRTMKHSLAWVDRSGS---LAELNGFEGNAAKAYFTALGHLVPQEFAFQ 177 + +++ I ++ W ++ L L G+EG + YF AL LV F F+ Sbjct 379 RLNRDRQISQVIEAIEELGVWQEKIAEVELLESLLGYEGFGTRIYFQALRALVQPPFTFE 438 Query 178 GRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVW 237 R+ RPP D NS++SLGY+LL++NI I L+ + G LH H L SDL+E + Sbjct 439 HRTRRPPTDPVNSLLSLGYTLLHQNIHSLILAVGLHPHYGNLHVPRSNHPALVSDLIEEF 498 Query 238 RAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKGD 297 RAP++D V+ L+ G+ F+ + + G V+ +A + + + ++++ T+ Sbjct 499 RAPVVDSLVIYLVNSGIFTPEDFTPSDERGGVYIYSDALKKYLKHWHDKLSLKTTH---- 554 Query 298 PHR-YTFQYALDLQLQ 312 PH Y Y L+LQ Sbjct 555 PHTGYKVSYYRCLELQ 570 >gi|320161859|ref|YP_004175084.1| hypothetical protein ANT_24580 [Anaerolinea thermophila UNI-1] gi|319995713|dbj|BAJ64484.1| hypothetical protein ANT_24580 [Anaerolinea thermophila UNI-1] Length=344 Score = 147 bits (372), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 94/296 (32%), Positives = 146/296 (50%), Gaps = 11/296 (3%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGE-----SQYPIETLDGITLFGRPTMTTPFIVE 55 M LYV S++ + RV V +E E +Q PI + I LFG +TTP + Sbjct 8 MPPLYVVQQNSKLRLNNRRVQV-EQETDEGIQVLAQIPIGQVSEIILFGNVGLTTPLMDA 66 Query 56 MLKRERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQ 115 +L + T DG Y+G +S + P R Q + P+F L ++K V K+ +Q Sbjct 67 LLYEGIPVIFLTRDGDYRGILSGGLTPHVPLRRAQYRALEKPSFSLEMAKGFVRAKLRHQ 126 Query 116 QALI----RAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVP 171 + L+ R ++E I M+H++ V R SL+ L G EG+A AYF+ L L Sbjct 127 RTLLQRQNRPPKQDASLSEVIERMEHAIDEVQRKTSLSSLRGLEGSATAAYFSGLRQLFN 186 Query 172 QEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLAS 231 E+ F R RPP D N ++SLGY+LL ++ + A++ L+ Y GFLH+ + L Sbjct 187 PEWKFDARLRRPPPDPVNVLLSLGYTLLAQDCVAAVQAVGLDPYAGFLHEVAYNRPALGL 246 Query 232 DLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRI 287 DL+E +R P++D VL + G + + F+ V + R +AF R+ Sbjct 247 DLLEEFR-PLVDGVVLWICHSGKICPQQFTPGPPERPVVLDDQGKRDFIKAFEERM 301 >gi|312899092|ref|ZP_07758470.1| CRISPR-associated protein Cas1 [Megasphaera micronuciformis F0359] gi|310619759|gb|EFQ03341.1| CRISPR-associated protein Cas1 [Megasphaera micronuciformis F0359] Length=346 Score = 144 bits (364), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 95/300 (32%), Positives = 148/300 (50%), Gaps = 14/300 (4%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M +Y+++ ++IS G I+ + P E L+ +TL GR ++ I +L++E Sbjct 18 MSHVYITEDGAKISKRGGHFILSRNSEVLFEIPEEGLESLTLIGRVQLSATVIERLLQKE 77 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 + + G++ GR+ + A + +QV T + LS+ K ++ KI NQQ L+R Sbjct 78 IPVTWLSKGGYFFGRLESTRHCNAVKQAKQVVLTGGSLY-LSMGKSMIEAKIHNQQVLLR 136 Query 121 AHT------SGQDVAESIRTMKHSLAWV-DRSGSLAELNGFEGNAAKAYFTALGHLVPQE 173 + S + E + +KH + V +RS EL G EG AA+ YF AL L+ E Sbjct 137 RYNRELESDSVRQKIEQLSRIKHKIMQVPNRS----ELMGNEGLAARIYFDALSELIEPE 192 Query 174 FAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDL 233 F F GR+ RPP D FN+++ GY+LL + A+ L+ Y G LH H LASDL Sbjct 193 FRFNGRTKRPPQDPFNAVIGFGYTLLLYELYTALSNVGLHPYFGCLHALKHRHPALASDL 252 Query 234 MEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATY 293 ME WR IID + L + F + D V+ RE + +A+ R+ + Y Sbjct 253 MEEWRPVIIDSLAMSLFNRHQLKAEHFERTED--GVYLNREGRYTFLQAYEKRLRTSNKY 310 >gi|219850296|ref|YP_002464729.1| CRISPR-associated protein Cas1 [Chloroflexus aggregans DSM 9485] gi|219544555|gb|ACL26293.1| CRISPR-associated protein Cas1 [Chloroflexus aggregans DSM 9485] Length=339 Score = 144 bits (363), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 100/326 (31%), Positives = 160/326 (50%), Gaps = 8/326 (2%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LYV + + I R+ V P+ LD I +FG ++TP + +L R Sbjct 1 MATLYVIEQGAEIGCDGERIEVRRGADIIGSVPLVKLDDIVIFGNVGISTPAMKRLLDRG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIR 120 ++ T DG YQGR+ ++ Q DPA L+L++R V K+ NQ+AL++ Sbjct 61 IEVTFMTVDGRYQGRLIGQVTAHVALRHAQYACAADPARALALAQRFVEGKLRNQRALLQ 120 Query 121 AHTSGQ-----DVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFA 175 + + + + ++ + V R+ L+ L G EG+A YF L L+ E++ Sbjct 121 RFSRNRAEPPPEAQAAADDLEAYIKRVKRTTQLSSLLGVEGSATARYFAGLRSLIGPEWS 180 Query 176 FQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLME 235 F GR RPP D N ++SLGY+LL ++GA++ + Y+GFLH G +LA D+ME Sbjct 181 FSGRQRRPPPDPVNLLLSLGYTLLAHKVLGAVQAAGFDPYLGFLHSLDYGRPSLALDIME 240 Query 236 VWRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIK 295 +R +ID V+R+ DG + F + T E R+ AF R+ AT+ + Sbjct 241 EFRPILIDSLVVRICNDGRIRPEHFRPGEGERPIIITDEGKRAFLTAFEERMRTEATHPE 300 Query 296 G---DPHRYTFQYALDLQLQSLVRVI 318 G P + + + LQ + L RV+ Sbjct 301 GADSGPGKVPYTRCIALQARRLARVV 326 >gi|337286709|ref|YP_004626182.1| CRISPR-associated protein Cas1 [Thermodesulfatator indicus DSM 15286] gi|335359537|gb|AEH45218.1| CRISPR-associated protein Cas1 [Thermodesulfatator indicus DSM 15286] Length=338 Score = 142 bits (358), Expect = 9e-32, Method: Compositional matrix adjust. Identities = 90/326 (28%), Positives = 151/326 (47%), Gaps = 10/326 (3%) Query 4 LYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRERDI 63 LY+++ ++ R+ + E+ ++ ++ LD I +FGR + + +LK E + Sbjct 3 LYITEQGLKVRKEGQRLQFYKEKNVVREFRLDDLDEIYVFGRLNFSAAALQALLKHEIKV 62 Query 64 QLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALIRAHT 123 T G Y GR++ P Q D+ L +++ +++ KI NQ+ +R Sbjct 63 HFLTASGKYLGRLAPPRGKNVELRLAQFRAFDNEKRRLEIARAVIAGKIRNQKNFLRRQN 122 Query 124 ---SGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQE-FAFQGR 179 + + ++I ++H + + + SL L G EG AA+ YF G L E F GR Sbjct 123 RKLKNEKIGQAILKLRHKIKEAEDAQSLESLRGIEGQAAQVYFDVFGKLFQVEGLKFPGR 182 Query 180 STRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWRA 239 RPP D N+++SLGY+LL+ I E + Y+GFLH G +L DL E WR Sbjct 183 IRRPPPDPINALLSLGYTLLFAQIWSVAESTGFDPYLGFLHVPEYGRPSLVLDLAEEWRP 242 Query 240 PIIDDTVLRLIADGVVDTRAFSK-----NSDTGAVFATREATRSIARAFGNRIARTATYI 294 I+D V+RL V F++ D + T + R F R+ A Y Sbjct 243 LIVDSLVVRLFNWKAVKPEDFTEEPWDDEEDFTSFKLTPDGLRKFLAKFRERLDEEALYA 302 Query 295 KGDPHRYTFQYALDLQLQSLVRVIEA 320 + R +++Y + Q+ L RV++ Sbjct 303 PLN-KRLSYRYIMQQQVWHLARVLDG 327 >gi|312278318|gb|ADQ62975.1| CRISPR-associated protein, Cas1 family [Streptococcus thermophilus ND03] Length=266 Score = 141 bits (356), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 84/255 (33%), Positives = 137/255 (54%), Gaps = 2/255 (0%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELG-ESQYPIETLDGITLFGRPTMTTPFIVEMLKR 59 M LY S +S ++ R+I+ ++ + I +D + LFG +TT I + K Sbjct 1 MSDLYSQRSNYYLSLSEQRIIIKNDNKEIVKEVSISLVDNVLLFGNAQLTTQLIKALSKN 60 Query 60 ERDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI 119 + + F+ G + I T + Q + F L +++ I + K+ NQ AL+ Sbjct 61 KVNGYYFSNVGQFISSIETHRQDEFQKQELQAKAYFEEDFRLEVARSIATTKVRNQIALL 120 Query 120 RAH-TSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAFQG 178 R T G + S++ + ++ S+ E+ G+EG AK+YF L LVP +F F G Sbjct 121 REFDTDGVLDTSDYSRFEDSVSDIQKAYSITEIMGYEGRLAKSYFYYLNLLVPDDFHFNG 180 Query 179 RSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEVWR 238 RS RP D FNS ++ GYS+LY ++G I+++ L+ G +H+ + HATLASDL+E WR Sbjct 181 RSRRPAEDCFNSALNFGYSILYSCLMGLIKKNGLSLGFGVIHKHHQHHATLASDLIEEWR 240 Query 239 APIIDDTVLRLIADG 253 I+D+T++ LI +G Sbjct 241 PIIVDNTLMELIRNG 255 >gi|292669134|ref|ZP_06602560.1| CRISPR-associated fusion protein cas1 [Selenomonas noxia ATCC 43541] gi|292649186|gb|EFF67158.1| CRISPR-associated fusion protein cas1 [Selenomonas noxia ATCC 43541] Length=281 Score = 140 bits (353), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 86/250 (35%), Positives = 133/250 (54%), Gaps = 8/250 (3%) Query 53 IVEMLKRERDIQLFTTDGHYQGRI-STPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRK 111 +VE+L+ + + G++ GR+ ST V+ + RQ + R D F L++++++++ K Sbjct 1 MVELLRLGIPVTWLSRTGYFFGRLESTRHVNVFRQERQILLR--DSFFYLAMARKVIAAK 58 Query 112 ILNQQALIRAHTSGQDVAESIRTMKHSLAW---VDRSGSLAELNGFEGNAAKAYFTALGH 168 NQ L+R + + E M A + R + +L G+EG AK YF ALG Sbjct 59 AHNQFILLRRYNRSASLPEVRTAMAEITALSKHIPRCETNTQLMGYEGAIAKVYFRALGL 118 Query 169 LVPQEFAFQGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHAT 228 LVP+ FAF RS RPP+D FN+M+S GY+LL ++ + L+ Y GFLH H Sbjct 119 LVPEAFAFVKRSRRPPMDPFNTMLSFGYTLLMYDLYTVVNNEGLHPYFGFLHALKNRHPA 178 Query 229 LASDLMEVWRAPIIDDTVLRLIADGVVDTRAFSKNSDTG--AVFATREATRSIARAFGNR 286 LASDLME WR ++D VL L+ + F+ + + G +F TRE RA+ + Sbjct 179 LASDLMEEWRPVLVDAMVLSLVHHHEMRPEHFAPSEEEGRPGIFLTREGRAIFLRAYEKK 238 Query 287 IARTATYIKG 296 + T+ Y G Sbjct 239 MRATSLYGGG 248 >gi|328953000|ref|YP_004370334.1| CRISPR-associated protein Cas1 [Desulfobacca acetoxidans DSM 11109] gi|328453324|gb|AEB09153.1| CRISPR-associated protein Cas1 [Desulfobacca acetoxidans DSM 11109] Length=333 Score = 139 bits (351), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 88/281 (32%), Positives = 139/281 (50%), Gaps = 5/281 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M LY+S+ + + R++V E P+ ++ + +FG TT +L++ Sbjct 1 MAFLYLSEQGACLQKTGERLVVAKEGETLLDLPVGKVEAVLIFGNVQFTTQAAHLLLQQG 60 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILNQQALI- 119 ++ LFT G G++++P + Q R DP F L L+K IV K+ N + L+ Sbjct 61 VEMALFTRRGRLVGQLTSPFTKNVTLRQAQYDRAADPEFALDLAKIIVGAKLTNSRGLLQ 120 Query 120 ---RAHTSGQDVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQEFAF 176 R H E I + + + S +LA L G EG AA YF L +V F F Sbjct 121 EFARNHPESGLKGE-IERLTELILQIGGSPNLAALLGLEGAAAHTYFQGLARMVRHGFGF 179 Query 177 QGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEV 236 GR P D N+++SLGY+L+Y I ++ + Y+GF HQ GHATLASDL+E Sbjct 180 SGRQHHPAPDPVNALLSLGYTLVYNEISSLLDGMGFDPYMGFYHQPRYGHATLASDLLEE 239 Query 237 WRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATR 277 +RA ++D L LI + V + F ++ +G ++ E + Sbjct 240 FRALLVDRLTLSLINNRVFGEQDFFRHEPSGGMYLGDEPRK 280 >gi|254417359|ref|ZP_05031101.1| CRISPR-associated protein Cas1 [Microcoleus chthonoplastes PCC 7420] gi|196175794|gb|EDX70816.1| CRISPR-associated protein Cas1 [Microcoleus chthonoplastes PCC 7420] Length=354 Score = 139 bits (351), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 92/325 (29%), Positives = 160/325 (50%), Gaps = 5/325 (1%) Query 1 MVQLYVSDSVSRISFADGRVIVWSEELGESQYPIETLDGITLFGRPTMTTPFIVEMLKRE 60 M +Y+ + + I R I++ E + + PI + I +FG ++TP + L+ + Sbjct 21 MAAIYLIEQGTTIYKEYQRFIIYVSEKPKLEVPIREVQQILVFGNIQLSTPVMQVCLREQ 80 Query 61 RDIQLFTTDGHYQGRISTPDVSYAPRLRQQVHRTDDPAFCLSLSKRIVSRKILN-QQALI 119 + + G Y G + + + + QV R D AF +S+ IV K++N +Q L+ Sbjct 81 IAVVFLSQSGRYHGHLWSSEFRDLDQELVQVRRWGDAAFQFQVSQAIVYGKLMNSKQLLL 140 Query 120 RAHTSGQ--DVAESIRTMKHSLAWVDRSGSLAELNGFEGNAAKAYFTALGHLVPQ-EFAF 176 R + + DV +I + + ++ S SL L G+EG A YF ALG L+ F F Sbjct 141 RFNRKRKLPDVERAIIGINQDIEALEFSESLDRLRGYEGIGAARYFPALGQLITNSRFEF 200 Query 177 QGRSTRPPLDAFNSMVSLGYSLLYKNIIGAIERHSLNAYIGFLHQDSRGHATLASDLMEV 236 R+ +PP D NS++S GY+LL+ N++G I L+ Y+G H R LA DLME Sbjct 201 SLRNRQPPTDPVNSLLSFGYTLLFNNVLGFIIAEGLSPYLGNFHYGERQKPYLAFDLMEE 260 Query 237 WRAPIIDDTVLRLIADGVVDTRAFSKNSDTGAVFATREATRSIARAFGNRIARTATYIKG 296 R+ ++D VL ++ + + F TG V+ + A R + F R+ ++ Sbjct 261 MRSVVVDSLVLNIVNHSLFKPQDFDTVPSTGGVYLNQSARRVFLKQFETRMNEEVSH-PD 319 Query 297 DPHRYTFQYALDLQLQSLVRVIEAG 321 + T++ A+ LQ++ + + +G Sbjct 320 LQSKVTYRQAIQLQVRRYKQSLLSG 344 Lambda K H 0.321 0.135 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 611369523864 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40