BLASTP 2.2.25+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.



Reference for composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
           15,229,318 sequences; 5,219,829,388 total letters



Query= Rv2818c

Length=382
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

gi|15842359|ref|NP_337396.1|  hypothetical protein MT2885 [Mycoba...   775    0.0   
gi|323718575|gb|EGB27742.1|  csm6 family CRISPR-associated protei...   775    0.0   
gi|15609955|ref|NP_217334.1|  hypothetical protein Rv2818c [Mycob...   773    0.0   
gi|148824007|ref|YP_001288761.1|  hypothetical protein TBFG_12832...   773    0.0   
gi|289448479|ref|ZP_06438223.1|  csm6 family CRISPR-associated pr...   771    0.0   
gi|340627814|ref|YP_004746266.1|  hypothetical protein MCAN_28421...   733    0.0   
gi|298526287|ref|ZP_07013696.1|  conserved hypothetical protein [...   688    0.0   
gi|31793994|ref|NP_856487.1|  hypothetical protein Mb2842c [Mycob...   615    3e-174
gi|121638697|ref|YP_978921.1|  hypothetical protein BCG_2837c [My...   615    3e-174
gi|306781001|ref|ZP_07419338.1|  CRISPR-associated protein, Csm6 ...   478    7e-133
gi|308371143|ref|ZP_07423964.2|  hypothetical protein TMCG_02062 ...   298    8e-79 
gi|306781005|ref|ZP_07419342.1|  hypothetical protein TMBG_02955 ...   298    1e-78 
gi|298525991|ref|ZP_07013400.1|  predicted protein [Mycobacterium...   167    2e-39 
gi|315925049|ref|ZP_07921266.1|  conserved hypothetical protein [...   145    1e-32 
gi|257413192|ref|ZP_04742265.2|  CRISPR-associated protein, Csm6 ...   138    2e-30 
gi|224543479|ref|ZP_03684018.1|  hypothetical protein CATMIT_0268...   124    2e-26 
gi|296133515|ref|YP_003640762.1|  CRISPR-associated protein Csm6 ...   121    3e-25 
gi|331004045|ref|ZP_08327527.1|  hypothetical protein HMPREF0491_...   118    2e-24 
gi|292669136|ref|ZP_06602562.1|  conserved hypothetical protein [...   114    2e-23 
gi|253578032|ref|ZP_04855304.1|  conserved hypothetical protein [...   114    3e-23 
gi|291460043|ref|ZP_06599433.1|  CRISPR-associated protein, Csm6 ...   112    1e-22 
gi|323141543|ref|ZP_08076429.1|  putative CRISPR-associated prote...   110    4e-22 
gi|341822667|emb|CCC73591.1|  putative uncharacterized protein [M...   106    8e-21 
gi|238018272|ref|ZP_04598698.1|  hypothetical protein VEIDISOL_00...   102    8e-20 
gi|303231923|ref|ZP_07318631.1|  CRISPR-associated protein, Csm6 ...   101    2e-19 
gi|334126725|ref|ZP_08500673.1|  hypothetical protein HMPREF9081_...   100    4e-19 
gi|342213924|ref|ZP_08706637.1|  putative CRISPR type III-A/MTUBE...  98.6    2e-18 
gi|258645681|ref|ZP_05733150.1|  CRISPR-associated protein, Csm6 ...  97.1    5e-18 
gi|312899100|ref|ZP_07758478.1|  CRISPR-associated protein, Csm6 ...  94.7    2e-17 
gi|114567261|ref|YP_754415.1|  hypothetical protein Swol_1746 [Sy...  88.6    1e-15 
gi|229826475|ref|ZP_04452544.1|  hypothetical protein GCWU000182_...  88.6    2e-15 
gi|333976325|gb|EGL77194.1|  CRISPR-associated protein, Csm6 fami...  85.9    1e-14 
gi|322387549|ref|ZP_08061158.1|  hypothetical protein HMPREF9423_...  73.2    7e-11 
gi|322375481|ref|ZP_08049994.1|  CRISPR-associated protein, Csm6 ...  71.2    3e-10 
gi|270292491|ref|ZP_06198702.1|  conserved hypothetical protein [...  70.1    5e-10 
gi|315641548|ref|ZP_07896617.1|  csm6 family CRISPR-associated pr...  67.0    5e-09 
gi|322387548|ref|ZP_08061157.1|  hypothetical protein HMPREF9423_...  64.3    3e-08 
gi|57865879|ref|YP_189999.1|  hypothetical protein SERP2456 [Stap...  63.2    7e-08 
gi|329736405|gb|EGG72674.1|  CRISPR-associated protein, Csm6 fami...  62.8    1e-07 
gi|289549404|ref|YP_003470308.1|  CRISPR-associated protein Csm6 ...  59.3    1e-06 
gi|312278327|gb|ADQ62984.1|  Putative uncharacterized protein [St...  57.4    4e-06 
gi|339278119|emb|CCC19867.1|  hypothetical protein STH8232_1168 [...  57.0    5e-06 
gi|334308476|gb|EGL99462.1|  CRISPR-associated protein Csm6 [Lact...  56.6    7e-06 
gi|339278118|emb|CCC19866.1|  hypothetical protein STH8232_1167 [...  56.6    8e-06 
gi|227890800|ref|ZP_04008605.1|  conserved hypothetical protein [...  55.8    1e-05 
gi|325687525|gb|EGD29546.1|  hypothetical protein HMPREF9381_1059...  55.5    1e-05 
gi|55822919|ref|YP_141360.1|  hypothetical protein str0965 [Strep...  50.4    5e-04 
gi|55821001|ref|YP_139443.1|  hypothetical protein stu0966 [Strep...  46.6    0.007 
gi|301299687|ref|ZP_07205941.1|  putative CRISPR-associated prote...  44.3    0.034 
gi|325696574|gb|EGD38464.1|  hypothetical protein HMPREF9384_1721...  42.0    0.18  


>gi|15842359|ref|NP_337396.1| hypothetical protein MT2885 [Mycobacterium tuberculosis CDC1551]
 gi|13882657|gb|AAK47210.1| hypothetical protein MT2885 [Mycobacterium tuberculosis CDC1551]
Length=430

 Score =  775 bits (2000),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 382/382 (100%), Positives = 382/382 (100%), Gaps = 0/382 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA
Sbjct  49   VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  108

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE
Sbjct  109  EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  168

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
            LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS
Sbjct  169  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  228

Query  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240
            NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA
Sbjct  229  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  288

Query  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300
            ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA
Sbjct  289  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  348

Query  301  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  360
            LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA
Sbjct  349  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  408

Query  361  DLTLYDRLNDEIIRQIDMAPLG  382
            DLTLYDRLNDEIIRQIDMAPLG
Sbjct  409  DLTLYDRLNDEIIRQIDMAPLG  430


>gi|323718575|gb|EGB27742.1| csm6 family CRISPR-associated protein [Mycobacterium tuberculosis 
CDC1551A]
Length=424

 Score =  775 bits (2000),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 382/382 (100%), Positives = 382/382 (100%), Gaps = 0/382 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA
Sbjct  43   VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  102

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE
Sbjct  103  EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  162

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
            LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS
Sbjct  163  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  222

Query  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240
            NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA
Sbjct  223  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  282

Query  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300
            ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA
Sbjct  283  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  342

Query  301  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  360
            LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA
Sbjct  343  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  402

Query  361  DLTLYDRLNDEIIRQIDMAPLG  382
            DLTLYDRLNDEIIRQIDMAPLG
Sbjct  403  DLTLYDRLNDEIIRQIDMAPLG  424


>gi|15609955|ref|NP_217334.1| hypothetical protein Rv2818c [Mycobacterium tuberculosis H37Rv]
 gi|148662660|ref|YP_001284183.1| hypothetical protein MRA_2842 [Mycobacterium tuberculosis H37Ra]
 gi|289444367|ref|ZP_06434111.1| csm6 family CRISPR-associated protein [Mycobacterium tuberculosis 
T46]
 12 more sequence titles
 Length=382

 Score =  773 bits (1997),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 381/382 (99%), Positives = 382/382 (100%), Gaps = 0/382 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            +LFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA
Sbjct  1    MLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE
Sbjct  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
            LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS
Sbjct  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180

Query  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240
            NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA
Sbjct  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240

Query  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300
            ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA
Sbjct  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300

Query  301  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  360
            LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA
Sbjct  301  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  360

Query  361  DLTLYDRLNDEIIRQIDMAPLG  382
            DLTLYDRLNDEIIRQIDMAPLG
Sbjct  361  DLTLYDRLNDEIIRQIDMAPLG  382


>gi|148824007|ref|YP_001288761.1| hypothetical protein TBFG_12832 [Mycobacterium tuberculosis F11]
 gi|167968188|ref|ZP_02550465.1| hypothetical protein MtubH3_09199 [Mycobacterium tuberculosis 
H37Ra]
 gi|253798097|ref|YP_003031098.1| hypothetical protein TBMG_01155 [Mycobacterium tuberculosis KZN 
1435]
 21 more sequence titles
 Length=415

 Score =  773 bits (1997),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 382/382 (100%), Positives = 382/382 (100%), Gaps = 0/382 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA
Sbjct  34   VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  93

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE
Sbjct  94   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  153

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
            LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS
Sbjct  154  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  213

Query  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240
            NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA
Sbjct  214  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  273

Query  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300
            ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA
Sbjct  274  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  333

Query  301  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  360
            LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA
Sbjct  334  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  393

Query  361  DLTLYDRLNDEIIRQIDMAPLG  382
            DLTLYDRLNDEIIRQIDMAPLG
Sbjct  394  DLTLYDRLNDEIIRQIDMAPLG  415


>gi|289448479|ref|ZP_06438223.1| csm6 family CRISPR-associated protein [Mycobacterium tuberculosis 
CPHL_A]
 gi|289421437|gb|EFD18638.1| csm6 family CRISPR-associated protein [Mycobacterium tuberculosis 
CPHL_A]
Length=382

 Score =  771 bits (1991),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 380/382 (99%), Positives = 381/382 (99%), Gaps = 0/382 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            +LFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA
Sbjct  1    MLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE
Sbjct  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
            LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS
Sbjct  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180

Query  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240
            NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA
Sbjct  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240

Query  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300
            ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA
Sbjct  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300

Query  301  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  360
            LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLK LARETGA
Sbjct  301  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKSLARETGA  360

Query  361  DLTLYDRLNDEIIRQIDMAPLG  382
            DLTLYDRLNDEIIRQIDMAPLG
Sbjct  361  DLTLYDRLNDEIIRQIDMAPLG  382


>gi|340627814|ref|YP_004746266.1| hypothetical protein MCAN_28421 [Mycobacterium canettii CIPT 
140010059]
 gi|340006004|emb|CCC45173.1| hypothetical protein MCAN_28421 [Mycobacterium canettii CIPT 
140010059]
Length=382

 Score =  733 bits (1892),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 358/382 (94%), Positives = 369/382 (97%), Gaps = 0/382 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            +LFLSAEIAAFENADRRYSAAITRLAPETDVR V +T+PSVHRFDLFVP+FR+HL +LS+
Sbjct  1    MLFLSAEIAAFENADRRYSAAITRLAPETDVRAVIHTDPSVHRFDLFVPIFRDHLAQLSS  60

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPD TILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARA SKPGDRESPD YDLE
Sbjct  61   EFPDTTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARASSKPGDRESPDTYDLE  120

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
            LMWDANDDN+P A NRCFE TSAALGALLERANLKQLI SYDYSAAVTIAADSRLPD VS
Sbjct  121  LMWDANDDNEPAASNRCFETTSAALGALLERANLKQLIASYDYSAAVTIAADSRLPDHVS  180

Query  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240
            NLIRGAMHRSRLEHLVAP+FFK T FTYDPANKVAEY+SALALLAKREQWAEFAR+ATPA
Sbjct  181  NLIRGAMHRSRLEHLVAPRFFKGTVFTYDPANKVAEYVSALALLAKREQWAEFARAATPA  240

Query  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300
            ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA
Sbjct  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300

Query  301  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  360
            LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA
Sbjct  301  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETGA  360

Query  361  DLTLYDRLNDEIIRQIDMAPLG  382
            DLTLYDRLNDEIIRQIDMAPLG
Sbjct  361  DLTLYDRLNDEIIRQIDMAPLG  382


>gi|298526287|ref|ZP_07013696.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
 gi|298496081|gb|EFI31375.1| conserved hypothetical protein [Mycobacterium tuberculosis 94_M4241A]
Length=384

 Score =  688 bits (1776),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 340/342 (99%), Positives = 341/342 (99%), Gaps = 0/342 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA
Sbjct  14   VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  73

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE
Sbjct  74   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  133

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
            LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS
Sbjct  134  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  193

Query  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240
            NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA
Sbjct  194  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  253

Query  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300
            ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA
Sbjct  254  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  313

Query  301  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKD  342
            LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRIT +
Sbjct  314  LLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITMN  355


>gi|31793994|ref|NP_856487.1| hypothetical protein Mb2842c [Mycobacterium bovis AF2122/97]
 gi|289575518|ref|ZP_06455745.1| csm6 family CRISPR-associated protein [Mycobacterium tuberculosis 
K85]
 gi|31619588|emb|CAD95027.1| HYPOTHETICAL PROTEIN [FIRST PART] [Mycobacterium bovis AF2122/97]
 gi|289539949|gb|EFD44527.1| csm6 family CRISPR-associated protein [Mycobacterium tuberculosis 
K85]
Length=303

 Score =  615 bits (1587),  Expect = 3e-174, Method: Compositional matrix adjust.
 Identities = 302/303 (99%), Positives = 303/303 (100%), Gaps = 0/303 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            +LFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA
Sbjct  1    MLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE
Sbjct  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
            LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS
Sbjct  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180

Query  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240
            NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA
Sbjct  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240

Query  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300
            ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA
Sbjct  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300

Query  301  LLR  303
            LLR
Sbjct  301  LLR  303


>gi|121638697|ref|YP_978921.1| hypothetical protein BCG_2837c [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|224991189|ref|YP_002645878.1| hypothetical protein JTY_2831 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|121494345|emb|CAL72825.1| Hypothetical protein BCG_2837c [Mycobacterium bovis BCG str. 
Pasteur 1173P2]
 gi|224774304|dbj|BAH27110.1| hypothetical protein JTY_2831 [Mycobacterium bovis BCG str. Tokyo 
172]
 gi|341602735|emb|CCC65413.1| hypothetical protein BCGM_2820c [Mycobacterium bovis BCG str. 
Moreau RDJ]
Length=336

 Score =  615 bits (1587),  Expect = 3e-174, Method: Compositional matrix adjust.
 Identities = 303/303 (100%), Positives = 303/303 (100%), Gaps = 0/303 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA
Sbjct  34   VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  93

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE
Sbjct  94   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  153

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
            LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS
Sbjct  154  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  213

Query  181  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  240
            NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA
Sbjct  214  NLIRGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPA  273

Query  241  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  300
            ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA
Sbjct  274  ITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLA  333

Query  301  LLR  303
            LLR
Sbjct  334  LLR  336


>gi|306781001|ref|ZP_07419338.1| CRISPR-associated protein, Csm6 family [Mycobacterium tuberculosis 
SUMu002]
 gi|306785636|ref|ZP_07423958.1| cutinase cut1 [Mycobacterium tuberculosis SUMu003]
 gi|306789676|ref|ZP_07427998.1| cutinase cut1 [Mycobacterium tuberculosis SUMu004]
 9 more sequence titles
 Length=242

 Score =  478 bits (1230),  Expect = 7e-133, Method: Compositional matrix adjust.
 Identities = 236/238 (99%), Positives = 236/238 (99%), Gaps = 0/238 (0%)

Query  145  LGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVSNLIRGAMHRSRLEHLVAPKFFKDT  204
              ALLERANLKQLIVSYDYSAAVTIAADSRLPDQVSNLIRGAMHRSRLEHLVAPKFFKDT
Sbjct  5    FSALLERANLKQLIVSYDYSAAVTIAADSRLPDQVSNLIRGAMHRSRLEHLVAPKFFKDT  64

Query  205  AFTYDPANKVAEYISALALLAKREQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGR  264
            AFTYDPANKVAEYISALALLAKREQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGR
Sbjct  65   AFTYDPANKVAEYISALALLAKREQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGR  124

Query  265  VDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVR  324
            VDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVR
Sbjct  125  VDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVR  184

Query  325  NTAAHEIVSISEDRITKDGGLLPEQLLKILARETGADLTLYDRLNDEIIRQIDMAPLG  382
            NTAAHEIVSISEDRITKDGGLLPEQLLKILARETGADLTLYDRLNDEIIRQIDMAPLG
Sbjct  185  NTAAHEIVSISEDRITKDGGLLPEQLLKILARETGADLTLYDRLNDEIIRQIDMAPLG  242


>gi|308371143|ref|ZP_07423964.2| hypothetical protein TMCG_02062 [Mycobacterium tuberculosis SUMu003]
 gi|308329699|gb|EFP18550.1| hypothetical protein TMCG_02062 [Mycobacterium tuberculosis SUMu003]
Length=206

 Score =  298 bits (764),  Expect = 8e-79, Method: Compositional matrix adjust.
 Identities = 146/146 (100%), Positives = 146/146 (100%), Gaps = 0/146 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA
Sbjct  49   VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  108

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE
Sbjct  109  EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  168

Query  121  LMWDANDDNQPGAPNRCFEATSAALG  146
            LMWDANDDNQPGAPNRCFEATSAALG
Sbjct  169  LMWDANDDNQPGAPNRCFEATSAALG  194


>gi|306781005|ref|ZP_07419342.1| hypothetical protein TMBG_02955 [Mycobacterium tuberculosis SUMu002]
 gi|306789682|ref|ZP_07428004.1| hypothetical protein TMDG_00002 [Mycobacterium tuberculosis SUMu004]
 gi|306794315|ref|ZP_07432617.1| hypothetical protein TMEG_03957 [Mycobacterium tuberculosis SUMu005]
 11 more sequence titles
 Length=191

 Score =  298 bits (763),  Expect = 1e-78, Method: Compositional matrix adjust.
 Identities = 146/146 (100%), Positives = 146/146 (100%), Gaps = 0/146 (0%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA
Sbjct  34   VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  93

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE
Sbjct  94   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  153

Query  121  LMWDANDDNQPGAPNRCFEATSAALG  146
            LMWDANDDNQPGAPNRCFEATSAALG
Sbjct  154  LMWDANDDNQPGAPNRCFEATSAALG  179


>gi|298525991|ref|ZP_07013400.1| predicted protein [Mycobacterium tuberculosis 94_M4241A]
 gi|298495785|gb|EFI31079.1| predicted protein [Mycobacterium tuberculosis 94_M4241A]
Length=110

 Score =  167 bits (424),  Expect = 2e-39, Method: Compositional matrix adjust.
 Identities = 79/81 (98%), Positives = 80/81 (99%), Gaps = 0/81 (0%)

Query  262  MGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFES  321
            MGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFES
Sbjct  1    MGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFES  60

Query  322  RVRNTAAHEIVSISEDRITKD  342
            RVRNTAAHEIVSISEDRIT +
Sbjct  61   RVRNTAAHEIVSISEDRITMN  81


>gi|315925049|ref|ZP_07921266.1| conserved hypothetical protein [Pseudoramibacter alactolyticus 
ATCC 23263]
 gi|315621948|gb|EFV01912.1| conserved hypothetical protein [Pseudoramibacter alactolyticus 
ATCC 23263]
Length=469

 Score =  145 bits (366),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 123/433 (29%), Positives = 197/433 (46%), Gaps = 61/433 (14%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLA-------PETDVRIVTYTNPSVHRFDLFVPVFRN  53
            +L+LSAE+  F   D RY   + +LA       PE ++ I      +V  FD+F   F  
Sbjct  39   ILYLSAEMMEFHEKDDRYMYCLEKLARLQNRAMPEIEI-IERPELRNVQYFDIFFDEFWE  97

Query  54   HLVELSAEF-PDRTILLNTSSGTPAMQAAL-VAINVFGIPRTT-AVQVSTPARALSKPGD  110
             + +++ E   D  +LLN SSGTPAM++ L V   + G  R T  +QV TP + +++   
Sbjct  98   KISQITDEMAEDDELLLNVSSGTPAMKSGLEVLQTIRGFSRKTRLIQVDTPTKKMNE---  154

Query  111  RESPDAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIA  170
              + + +D+EL W+ + DN P   NRC E    +L  + +   +KQL+  YDY AA+ +A
Sbjct  155  -HAHEGFDVELAWEVDVDNAPDFKNRCHEFECRSLKNIQDEEIIKQLVKDYDYRAAMAVA  213

Query  171  ADSRLPDQVS-NLIRGAMHRSRLEHLVAPKFFKDTAFTYDP-----ANKVAEYISALALL  224
             D   PD    + ++ A  R  L+     K  K T     P     A K  EY   L + 
Sbjct  214  KDMPEPDPAYLDKLKLARARQLLDFSTVTKLEKKTGMDVTPVKSGDARKSFEYALLLWIK  273

Query  225  AKREQWAEFARSATPAIT----IVLRAAVAKHLPEDRYLDDMGRVDRR------------  268
              R ++ +F R+ TP I      +LR      + +  Y D  G V R+            
Sbjct  274  KDRREYVDFCRALTPLIVDLFEQILRCQCKIDINQYVYGDFPGWVRRKCEEEGWNEEERE  333

Query  269  --------------KLEREPEIRCALKHPPKSPNAEWYLYTKDWLALLRQFAPDRV--GA  312
                          +L+++ +I    +    S  A   + +   L L+ +F  +R    A
Sbjct  334  KRFRGAKICKWHKGRLKQDEKIFSVFQKAYSSGVANRNISSDHLLKLIEEFCKNRAIRDA  393

Query  313  LEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARETG--------ADLTL  364
             + +   E  +RN +AHE+VS++ED I    GL  +++LK++ R  G        AD   
Sbjct  394  AKQIREVEEAIRNDSAHEMVSVTEDVIEHRTGLTTDEILKLIKRLFGYTGYGIKEADWHS  453

Query  365  YDRLNDEIIRQID  377
            Y  +N EI++ ID
Sbjct  454  YQAMNQEIVQAID  466


>gi|257413192|ref|ZP_04742265.2| CRISPR-associated protein, Csm6 family [Roseburia intestinalis 
L1-82]
 gi|257204342|gb|EEV02627.1| CRISPR-associated protein, Csm6 family [Roseburia intestinalis 
L1-82]
Length=451

 Score =  138 bits (347),  Expect = 2e-30, Method: Compositional matrix adjust.
 Identities = 121/413 (30%), Positives = 190/413 (47%), Gaps = 44/413 (10%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTN------PSVHRFDLFVPVFRNH  54
            +L++S E+  F+  D RY   + RLA   D R + Y          VH FD F   FR  
Sbjct  43   ILYMSKEMLDFQEKDDRYRYCLDRLAKMQD-RPMIYEIIERRELTKVHEFDYFYEDFRKV  101

Query  55   LVELSAEFPDR-TILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRES  113
            +  +     D  T+LLN SSGTPAM++ L+ +   G      +QV+TP   L++    + 
Sbjct  102  ISHIYETMDDSDTLLLNVSSGTPAMKSGLLVLQTLGEFPAKVIQVATPVGKLNE----QV  157

Query  114  PDAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADS  173
             + YD+E +W+ ++DNQ GA NRC E     L  + +   +K+ I+ YDY AA+ + ADS
Sbjct  158  HEGYDVETLWELDEDNQEGAQNRCKEIQCPTLSKIKKEEIIKKHILVYDYQAALDV-ADS  216

Query  174  RLPD----QVSNLIRGAMHRSRLEHLVAPKFFKDTAFT-----YDPANKVAEYISALALL  224
             LP     Q  +LI  A  R  L+ +   K  + T F      Y    K  EY   + + 
Sbjct  217  -LPAEQTVQYRDLIYQAARRVLLDFVNVDKTIQKTNFQCLPVRYSSQRKYFEYALTIDIR  275

Query  225  AKREQWAEFARSATPAITIVLRAAVAKH--LPEDRYLDDMGRVDR-------RKLEREPE  275
             KR ++ +F RS TP +  +    + K   +  D Y D   R  +       +KL     
Sbjct  276  LKRGEYVDFIRSITPIVVDLFEMILKKQCGIIVDDYCDQYKRAGQWKRMWSAKKLNGTEV  335

Query  276  IRCALKHPPKSPN--AEWYLYTKDWLALLRQFAPD-RVGAL-EVLGRFESRVRNTAAHEI  331
             +    H  K         +Y++    L   F+ D R+  L E L   ES +RN AAHEI
Sbjct  336  GKVLNSHYQKMEKRFEAKDVYSEHLKILTDHFSSDTRLKQLMEDLRNVESNIRNLAAHEI  395

Query  332  VSISEDRITKDGGLLPEQLLKILARETG-ADLTL-------YDRLNDEIIRQI  376
            VS++++ I    G     ++  +    G  ++++       YD +N +I+ Q+
Sbjct  396  VSVTDETIKNLTGFYGRDIMSKIKELFGYTEISIRKGYWDSYDEMNRKILEQM  448


>gi|224543479|ref|ZP_03684018.1| hypothetical protein CATMIT_02688 [Catenibacterium mitsuokai 
DSM 15897]
 gi|224523606|gb|EEF92711.1| hypothetical protein CATMIT_02688 [Catenibacterium mitsuokai 
DSM 15897]
Length=445

 Score =  124 bits (311),  Expect = 2e-26, Method: Compositional matrix adjust.
 Identities = 112/413 (28%), Positives = 191/413 (47%), Gaps = 42/413 (10%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAP----ETDVRIVTYTN-PSVHRFDLFVPVFRNHL  55
            +L+LS E+A   +    Y   I +LA       DV  +       V  FD F   FRN L
Sbjct  39   ILYLSKEMAEKHHKYNPYGYCIEKLAELQSRHIDVEYIERNELTKVQEFDYFYKDFRNIL  98

Query  56   VELSAEF-PDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESP  114
            +++  +   D   LLN SSGTPAM++ LV +   G      +QV TP   L++   +E+ 
Sbjct  99   MDIMGDMDEDDEFLLNISSGTPAMKSGLVVLKTLGELPCRTIQVVTPTGKLNEHSHKEN-  157

Query  115  DAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIA---A  171
               D E +W+ ++DN P + NRC E     L  + +   +K+ I +YDYSAA+ +A    
Sbjct  158  ---DYETLWELDEDNNPDSANRCIEVECPTLAIIKKEEIIKKHIEAYDYSAALQVAKTIK  214

Query  172  DSRLPDQVSNLIRGAMHRSRLEHLVAPKF-FKDTAFTY----DPANKVAEYISALALLAK  226
             S +     +LI  A +R  L++  A +   K+  + +    D   K+ EY   + +  +
Sbjct  215  KSAMDKGYYSLIEMAKYRESLDYKKALEISSKEKVYCFPVTDDKGIKLFEYALNIDVKRR  274

Query  227  REQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGRVDRRK--------LER--EPEI  276
            R ++A+F RS TP    +    +      D  ++   R++++K        LE+    ++
Sbjct  275  RHEYADFIRSITPLFVDLFELVLKHETGID--INKYCRIEKKKKHSMRVWDLEKLNGSDV  332

Query  277  RCALKHPPKSPNAEWYLYTKDWLALLRQFAP-DRVGALEV---LGRFESRVRNTAAHEIV  332
              +L +   +   E  +Y++  + LL  F P  R  A ++   L   E  +RN  AHE+V
Sbjct  333  LKSLNNYYLNGFKEGPIYSEPLVVLLNDFIPSSRKEAADLVSDLRSVEGNIRNITAHEMV  392

Query  333  SISEDRITKDGGLLPEQLLKILARE-TGADLTL-------YDRLNDEIIRQID  377
             +++D I          ++K + +  +  DL +       YD +N  II +ID
Sbjct  393  CVTDDVIKDKTNFSSNAIMKKIEKVFSYTDLDIKDEYWNSYDLMNQLIIERID  445


>gi|296133515|ref|YP_003640762.1| CRISPR-associated protein Csm6 [Thermincola sp. JR]
 gi|296032093|gb|ADG82861.1| CRISPR-associated protein Csm6 [Thermincola potens JR]
Length=460

 Score =  121 bits (303),  Expect = 3e-25, Method: Compositional matrix adjust.
 Identities = 123/428 (29%), Positives = 188/428 (44%), Gaps = 70/428 (16%)

Query  2    LFLSAEIAAFENADRRYSAAITRLAPE----TDVRIVTYTNPSVHRFDLFVPVFRNHLVE  57
            +F S E+   E  DRR++ A+  L+ E     D  ++     + H FD F+ VF  HL E
Sbjct  38   IFFSGEMGRREEKDRRFTRAVDLLSRELSWPIDKHLIFSGIQNPHDFDAFIGVFSKHLEE  97

Query  58   LSAEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTP-ARA-LSKPGDRESPD  115
            +S + P+ TILLN SSGTP M + L    V    R   VQV TP ARA LSK G    PD
Sbjct  98   ISKDHPEATILLNVSSGTPQMMSMLCLETVVSSKRLVPVQVITPAARANLSKMG---GPD  154

Query  116  AYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRL  175
             YD+E  +  N DN+P APNRC +    +    L R  +  L+ +Y+Y  A  I     L
Sbjct  155  -YDVEWEFGNNLDNEPDAPNRCVQPDIQSFKRALARGQVTALLENYNYEGAALILGGYGL  213

Query  176  P--DQVSNLIRGAMHRSRLEHLVAPKFFKDT-AFTYDP-----ANKVAEYISALALLAKR  227
                 V  L+R A+    L+       F++  A T  P       ++ EY + + LL + 
Sbjct  214  GTDSTVMGLLRFAIALKNLDSDAKGSQFQEARALTGYPQMDWECLEICEYCNVVKLLQRT  273

Query  228  EQWAEFARSATPAITIVLRAAVAKH--------LPEDRYL----DDMGRVDRRKLERE--  273
             Q A+F     P +T  L+    K+        + E+R+     +  G+   R + R+  
Sbjct  274  GQLADFLLRLNPLVT-ELQTKFLKYCLGFAVEAIIEERHCAGRKNTAGKFTERLVRRDKI  332

Query  274  ----PEIRCALKHPPKSPNAEW----------------YLYTKDWLALLRQFAPDRVGAL  313
                PE+   L +  +  N E+                +   K+  +  R FA   +  +
Sbjct  333  RALNPEL---LAYLDECHNGEYRDGSHVNIRMQNCLINFFLRKNPDSQTRSFA-GFLDTM  388

Query  314  EVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKIL---------ARETGADLTL  364
            E+L    +R RN AAH +  + E+ I +  GL   Q++  L          R      T+
Sbjct  389  EIL----NRDRNLAAHNLYGVLEEDIKQRSGLTGGQIVDKLENLIKFIFKGRCKPEIFTI  444

Query  365  YDRLNDEI  372
            +D +N+ I
Sbjct  445  FDTVNNVI  452


>gi|331004045|ref|ZP_08327527.1| hypothetical protein HMPREF0491_02389 [Lachnospiraceae oral taxon 
107 str. F0167]
 gi|330411631|gb|EGG91039.1| hypothetical protein HMPREF0491_02389 [Lachnospiraceae oral taxon 
107 str. F0167]
Length=462

 Score =  118 bits (295),  Expect = 2e-24, Method: Compositional matrix adjust.
 Identities = 113/419 (27%), Positives = 183/419 (44%), Gaps = 48/419 (11%)

Query  2    LFLSAEIAAFENADRRYSAAITRLAPETD-----VRIVTYTNPSVHRFDLFVPVFRNHLV  56
            L+++ EI      D RY   I +LA + +     V I      +V  +D F+  F   + 
Sbjct  38   LYMTKEIYEKHEKDDRYRFFINKLAEQKNKEIESVIIADKERDNVQEYDPFLFKFEEEIN  97

Query  57   ELSAEF-PDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPD  115
             +  E   D    +N SSGTPAM+ ALV +          +QVSTP   + K  +     
Sbjct  98   NIINELNDDDNFFINISSGTPAMKNALVILQDLNEYNCKFIQVSTP---IKKMNEHTHGK  154

Query  116  AYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRL  175
              +LELMW+ N + +    NRC E+   +L  L +   +K+ I  YDY AA+++A D   
Sbjct  155  VLELELMWEMNMELEKEGNNRCVESKCPSLSRLRKEEIIKKHIDEYDYRAALSVAGDME-  213

Query  176  PDQVSNLIR---GAMHRSRLEHLVAPKFFKDTAFTYDP-----ANKVAEYISALALLAKR  227
             +   N I     A++R  L        +K   F   P     A K+ EY   L +  KR
Sbjct  214  KNSTKNYIDELLSAVNRYNLNMKKVDNEYKKEGFDITPVKAGDARKLFEYALWLNIKVKR  273

Query  228  EQWAEFARSATPAIT----IVLRA----AVAKHLPEDRY---LDDMGRVDRRKLEREPEI  276
            E++ +F R  TP +     +VL+      + K+   + Y   + D G++ +    ++  I
Sbjct  274  EEYIDFVRGITPIVVELFEVVLKGRGKLDINKYCTLNGYKVRVWDTGKIAKNIPGKDTNI  333

Query  277  R------CALKHPPKSPNAEW---YLYTKDWLALLRQFAPDRV--GALEVLGRFESRVRN  325
            +        +KH  K    E+    +Y++  L L++    D V       +   E +VRN
Sbjct  334  KDIVNKEYKIKHSDKDKVEEFRFGMIYSEALLYLIKNLIDDEVLFDIASNIRTVEEKVRN  393

Query  326  TAAHEIVSISEDRITKDGGLLPEQLL---KILARETGADLT-----LYDRLNDEIIRQI  376
             AAH+IV++  + I    G  P Q++   K L   T   +       YD +N E+ R+I
Sbjct  394  LAAHDIVALDSNDIKNRTGFTPVQIMDKIKKLFNYTNFGIKPEYWDSYDDMNKELKRRI  452


>gi|292669136|ref|ZP_06602562.1| conserved hypothetical protein [Selenomonas noxia ATCC 43541]
 gi|292649188|gb|EFF67160.1| conserved hypothetical protein [Selenomonas noxia ATCC 43541]
Length=459

 Score =  114 bits (286),  Expect = 2e-23, Method: Compositional matrix adjust.
 Identities = 109/414 (27%), Positives = 184/414 (45%), Gaps = 49/414 (11%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTN-PSVHRFDLFVPVFRNHLVELS  59
            VLF + E+   E  ++RY+ A+  +AP+  +    +T+     R++ F  +    + +L 
Sbjct  41   VLFFTKEMGEIERNEKRYTTAVRYVAPDCIIDPPIFTDIVDASRYEEFSQILPQTVQDLL  100

Query  60   AEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDL  119
             ++P+  ILLN SSGTP ++  L  +      R   +Q  TP R  + P  + +P+  +L
Sbjct  101  QKYPEHEILLNLSSGTPQIKTILAMLAADN-ERCIGIQTVTPERRANNP-QKITPE--EL  156

Query  120  ELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRL-PDQ  178
            + M   N+DN+PGA  RC E          E+  +  LI SY+Y+AA+T+A +SRL P  
Sbjct  157  QSMLQMNEDNKPGAVRRCDEPPLKIFRYHAEKNRILALIHSYEYNAALTLARNSRLVPTD  216

Query  179  VSNLIRGAMHRSRL----EHLVAPKFFKDTAFTY-DPANKVAEYISALALLAKREQWAEF  233
               L++ A  R+ L       + P++     F + +   ++ EY   + +  + E+ + F
Sbjct  217  AKTLLKHAAARTMLLPDKARKILPEYNGQKLFLFKEDEERIVEYFLVMQIDQENERLSNF  276

Query  234  ARSATPAITIVLRAAVAKHLPEDR-------------YLDDMGRVDRRKLEREP-EIRCA  279
                TP +   L   VAK++   R             Y  D   + R+K+E+        
Sbjct  277  MLRITPFLYEFLHDYVAKNVKGGRKNAQHIDNLCIKKYNTDGYILQRKKIEKNARNFLDL  336

Query  280  LKHPPKSPNAEWYLYTK-DWLALLR--------------QFAPDRVGALEVLGRFESRVR  324
            L       NA  Y  T   +L L+               Q   D +  L  LG    +VR
Sbjct  337  LDQEFAGSNAHQYTNTDLSFLLLIHYCTYMQEAGLAKDAQLHSDMMDELGKLGTVR-KVR  395

Query  325  NTAAHEIVSISEDRITKDGGLLPEQLL----KILARETGADL----TLYDRLND  370
            N+ AH IV+++ +   KD  + P  L+    K+L    G  +    T Y R+N+
Sbjct  396  NSVAHVIVNVTRESFQKDTQMTPPALMDTFAKMLTLVYGTKVKEARTTYSRINN  449


>gi|253578032|ref|ZP_04855304.1| conserved hypothetical protein [Ruminococcus sp. 5_1_39B_FAA]
 gi|251850350|gb|EES78308.1| conserved hypothetical protein [Ruminococcus sp. 5_1_39BFAA]
Length=438

 Score =  114 bits (284),  Expect = 3e-23, Method: Compositional matrix adjust.
 Identities = 107/406 (27%), Positives = 185/406 (46%), Gaps = 37/406 (9%)

Query  2    LFLSAEIAAFENADRRYSAAITRLAP----ETDVRIVTYTNP-SVHRFDLFVPVFRNHLV  56
            L+LS E+      D RY   +  L      + ++ I+  ++   V ++D+F   F   + 
Sbjct  38   LYLSKEMMENHKKDNRYVKTLELLGEFLHHKFEIHIIENSDMIDVQQYDIFYNEFHRIIA  97

Query  57   ELSAE-FPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPD  115
            E+  +  P+  +L+N +SGTPAM++AL+ +      R   +QVSTP +      + E  D
Sbjct  98   EIEEQKGPEDILLVNMASGTPAMKSALLVMATLSEYRFLPIQVSTPQK--KSNLEHEERD  155

Query  116  AYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSR-  174
             YD++  W+ N DN+  A NRC E     L  LL+   +K+ +++YDY AA+ +  + + 
Sbjct  156  EYDVDANWELNMDNEEAAENRCQEVKCLNLMRLLKIDMIKKHLLAYDYHAALAVGKEIKE  215

Query  175  -LPDQVSNLIRGAMHRSRLEHLVAPKFFKD-----TAFTYDPANKVA-EYISALALLAKR  227
             L       +  A  RS L+     +   +     TA   +   KV  EY+ AL L  KR
Sbjct  216  DLSPVAYQWLETADARSLLDWTRMNRVLPENNGIITAVRGENEKKVLFEYMLALDLKVKR  275

Query  228  EQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALKHPPKSP  287
             ++A+F R+ TP    +L   + +         D+ R  +R  +R  +    +       
Sbjct  276  GEYADFIRAITPLGVDLLEIVLEQSCD-----IDITRYYKRNNQRIWDKNRLVGEILDIL  330

Query  288  NAEWY------LYTKDWLALLRQFAPD--RVGALEVLGRFESRVRNTAAHEIVSISEDRI  339
            N ++Y      +Y+   L ++++   D   V  ++ L   E  VRN AAH IVS++ + I
Sbjct  331  NQKFYPFRYGPVYSAHLLEIIQKKCTDTLMVQRIQELVNIEQNVRNVAAHNIVSVTPEWI  390

Query  340  TKDGGLLPEQLLKILA--------RETGADLTLYDRLNDEIIRQID  377
             +  G   + +L IL              +   YD +N  II ++D
Sbjct  391  KERTGKSVDDILWILKYVCEQVKINTRKENWNSYDSMNKRIINELD  436


>gi|291460043|ref|ZP_06599433.1| CRISPR-associated protein, Csm6 family [Oribacterium sp. oral 
taxon 078 str. F0262]
 gi|291417384|gb|EFE91103.1| CRISPR-associated protein, Csm6 family [Oribacterium sp. oral 
taxon 078 str. F0262]
Length=434

 Score =  112 bits (280),  Expect = 1e-22, Method: Compositional matrix adjust.
 Identities = 110/422 (27%), Positives = 196/422 (47%), Gaps = 54/422 (12%)

Query  2    LFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYT---NPS---VHRFDLFVPVFRNHL  55
            L++S EI  ++ AD RY+  + +L  E   R + Y     P    V  F++F   F+  +
Sbjct  20   LYMSREIIQYQEADERYTYCLKKLG-ELQNREIEYELIRRPELVEVQDFEIFYREFKEEI  78

Query  56   VELSAEF-PDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESP  114
             ++  E   D  ++LN SSGTPAM++ L+ I         AVQV TP RA+++   ++  
Sbjct  79   DKIRKEMGEDDELILNLSSGTPAMKSWLLVIRTMNELSCKAVQVVTPDRAMNEHRHKD--  136

Query  115  DAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSR  174
              Y ++ +W+ + DN+ GA NRC E    +L  + +  N+++LI  YDY AA+ +AA+ +
Sbjct  137  --YQVKELWELDPDNEGGAENRCREVPCPSLSRVRQEVNIRKLIREYDYHAALELAAELK  194

Query  175  LPDQ-VSNLIRGAMHRSRLEHLVAPKFFKDTAFT--------YDPANKVAEYISALALLA  225
              ++    LIR A  R  L+     K  +                   + EY   + +  
Sbjct  195  DHEKPYMKLIRVAEERELLDMDAVEKKLETNHLKGLYRLPIRKGEKRDIFEYALVMQIRL  254

Query  226  KREQWAEFARSATPAITIVLRAAVAK-HLPEDRYL---DDMGRVDRRKLERE---PEIRC  278
            +R ++A+F R+ +P +  + +  + K  +  + Y+   +     DR KL  +    EI  
Sbjct  255  RRGEYADFIRAISPILYRLYKRIMKKLGICLEEYVSGTETKTVWDREKLSGDMAGKEILK  314

Query  279  ALKHPPKSPNAEWY--LYTKDWLALLRQFAPDR-----VGALEVLGRFESRVRNTAAHEI  331
             L+   KS +   +  +Y      +++  + D+     VG L      E +VRN AAH+I
Sbjct  315  ILEGAYKSGDGFRFGNVYPVHMQKIIQAKSDDKELKKLVGELR---EAEEKVRNQAAHQI  371

Query  332  VSISEDRI----------TKDGGLLPEQLLKILARETGADL------TLYDRLNDEIIRQ  375
            VS+++  I           +D   + + + K +      D+        YD++N+ IIR 
Sbjct  372  VSVNKKTIREWMEKEGCKDRDAEWIMDGIKKAIGYAEIIDIANKEVWNSYDQMNEVIIRL  431

Query  376  ID  377
            +D
Sbjct  432  MD  433


>gi|323141543|ref|ZP_08076429.1| putative CRISPR-associated protein, Csm6 family [Phascolarctobacterium 
sp. YIT 12067]
 gi|322414002|gb|EFY04835.1| CRISPR-associated protein, Csm6 family [Phascolarctobacterium 
sp. YIT 12067]
Length=437

 Score =  110 bits (275),  Expect = 4e-22, Method: Compositional matrix adjust.
 Identities = 107/403 (27%), Positives = 186/403 (47%), Gaps = 32/403 (7%)

Query  2    LFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAE  61
            +FLSAE++A E     YS AI    PE     +     +V   +  VP+    L EL  E
Sbjct  36   IFLSAEMSAKEKNRHIYSKAIEYNVPECKFDFIYTDIVNVQLMEELVPLAEGFL-ELRKE  94

Query  62   FPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLEL  121
            FP+  ILLN SSGTP M+  +  +         A+QV +P RA ++     + D  D+ +
Sbjct  95   FPEEEILLNLSSGTPQMKTVMSFLAT-DFENVRAIQVDSPQRASNRTA-HATQDNEDINV  152

Query  122  MWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLP--DQV  179
            + + N DN P    RC EA  + L     R  L  LI +Y+Y AA+T+   +++   ++ 
Sbjct  153  VIENNFDNVPDYTCRCHEAPLSLLRRYSIRHQLISLINNYEYRAALTMYNKNKIMFVEET  212

Query  180  SNLIRGAMHRSRLEHLVAPKF---FKDTAFTYDPANKVAEYISALALLAKREQWAEFARS  236
             NL+R A  RS+L  L+   F    K+  +  +   K+ E++  + L  ++ + AEF   
Sbjct  213  GNLLRHADLRSKL--LINEAFKGMGKENIYNNNSVKKLNEFLMVMELHQRKGELAEFIPK  270

Query  237  ATPAITIVLRAAVAKH--LPEDRYL------DDMGRVDRRKLERE-PEIRCALKHPPKSP  287
             TP +  +L      H  L  +R+       +   ++   KL +E P++   L +  +  
Sbjct  271  LTPFLYELLLYYFENHVALKLERFCYRKRNNNSSWKISAEKLRKEAPDVFTYLNYYFRQG  330

Query  288  NAEWYLYTKDWLAL---LRQFAPDRVGALEVLGRFESRVRNTAAHEIVS-ISEDRITK-D  342
              +  L   + L +   L+    + +G L++L   E   RN  AH I++ ++E+ +   +
Sbjct  331  FRDTDLSFSNMLLILESLKSVKTELMGELQILREVEKNQRNKIAHTILTDVTEENLQAIE  390

Query  343  GGLLPEQLLK--------ILARETGADLTLYDRLNDEIIRQID  377
              L   Q+++        I+  E+     +YD LN  I+  ++
Sbjct  391  PKLSSYQIIQHLRKAFLLIMEGESICKRNVYDDLNRRIVDSLN  433


>gi|341822667|emb|CCC73591.1| putative uncharacterized protein [Megasphaera elsdenii DSM 20460]
Length=450

 Score =  106 bits (264),  Expect = 8e-21, Method: Compositional matrix adjust.
 Identities = 100/388 (26%), Positives = 164/388 (43%), Gaps = 46/388 (11%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VL+ +AE+   E     Y+  I  + P   V  +       H +D ++     H+++L  
Sbjct  35   VLYFTAEMEKRERNTHMYTLGIEHVQPGCPVESLYSGIVDAHLYDAYLHDLPGHVLKLHQ  94

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
             +P+  ILLN SSGTP ++  L AI          +QV++P    S   +    D  D+E
Sbjct  95   IYPEAEILLNLSSGTPQIKVVL-AIMSTEYAWCRGIQVASPEHR-SNTNNIPVQDEEDVE  152

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSR-LPDQV  179
             M   N+D++P APNRC E     L    E+  +  L+  Y+Y  A      S  +  Q 
Sbjct  153  EMLACNEDDEPDAPNRCEEPHLEILRFYREKYEIMSLVNQYEYMGAWAFCKGSHTISAQT  212

Query  180  SNLIRGAMHRSRLE----HLVAPKFFKDTAFTYD-PANKVAEYISALALLAKREQWAEFA  234
              LI+ AM+RS L+      +  K+     F ++     + EY+  + +  +++Q+A F 
Sbjct  213  KKLIQFAMYRSDLQTKAAQQIMRKYHGQALFPFEREGESLTEYLLTMQIHKEKKQYASFM  272

Query  235  RSATPAIT--IVLRAAVAKHLPEDRYLDDMGRVDRRKLERE--------PEIRCALKHPP  284
               +P +    V  A +   +P   Y + +    RR L R+        PE+   L H  
Sbjct  273  VQISPFLYELFVTYAKMNLKIPLLNYREKVA--GRRILRRQTLLQKPQGPELIAYLDHVW  330

Query  285  KSPNAEWYLYTKDW-LALLRQ---FAPDRVGALEVLGRFE-----------------SRV  323
              P      Y  +    LL Q   FA    GA +     E                  ++
Sbjct  331  PQP-----FYDSELSFILLYQVFCFAEQFDGAKDAEKHHEFMTDPLMNSANPYMDKLRKL  385

Query  324  RNTAAHEIVSISEDRITKDGGLLPEQLL  351
            RN  AHEI++++E+ I K  GL P+ ++
Sbjct  386  RNNTAHEIINVTEETIQKRTGLTPDDIM  413


>gi|238018272|ref|ZP_04598698.1| hypothetical protein VEIDISOL_00096 [Veillonella dispar ATCC 
17748]
 gi|237864743|gb|EEP66033.1| hypothetical protein VEIDISOL_00096 [Veillonella dispar ATCC 
17748]
Length=439

 Score =  102 bits (255),  Expect = 8e-20, Method: Compositional matrix adjust.
 Identities = 107/417 (26%), Positives = 185/417 (45%), Gaps = 54/417 (12%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            +L LS ++   E A+ R++ A+  +  + D++I+      VHR D+  P F +H  E  +
Sbjct  35   ILVLSKDMEQKEAANHRFTKALKHVKADLDIKIIHTGLEDVHRIDVLQP-FVDHFYETLS  93

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESP---DAY  117
             +PD  IL+N SSGTP M+  +  ++V        +QV +P R      +R  P   D  
Sbjct  94   TYPDAEILINLSSGTPQMKLIMSYLSVEH-DAVRGIQVDSPQRG----SNRSEPAVNDDE  148

Query  118  DLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQ----LIVSYDYSAAVTI----  169
            D+EL+ + N D+Q  + NRC E         ++R N+KQ    LI SY Y  A++     
Sbjct  149  DIELVIENNFDDQEDSENRCHEPQM----GYIKRNNIKQSLHTLITSYKYKEAISSYHSY  204

Query  170  --AADSRLPDQVSNLIRGAMHRSRLEH---LVAPKFFKDTA----FTYDPANKVAEYISA  220
                +S + + V  L+  A  R  L +   L   +    T+    FT     K+ E++  
Sbjct  205  KRTFESDVVNDVLPLLEHAQLRLGLNYDDALQKARKVGSTSLSSLFTDKELRKLHEFLML  264

Query  221  LALLAKREQWAEFARSATPAITIVLRAAVAKHLP------EDRYLDDMGRVDRRKLERE-  273
            + +  K+ Q  +F    TP +  ++R    K L       E +    M R+D    + + 
Sbjct  265  MEVRLKQGQIEDFVLKTTPFMYELMRYYFTKELNVNWRQVEKKTSKGM-RLDMVAFKNQY  323

Query  274  PEIRCALKHPPKSPN-AEWYLYTKDWLALLRQFAPDRVGA-----LEVLGRFESRVRNTA  327
            P++  + +    +P   E  +     L +L  +  D V +     L+ + R E ++RN  
Sbjct  324  PKLYESWQENSDTPYLQELQVSFYHMLHMLEDY--DTVDSSLLKHLKEIRRIERKIRNKI  381

Query  328  AHEIVSISEDRITKDGGLLPEQLLK--------ILARETGADLTLYDRLNDEIIRQI  376
            AHE+V  +E  I     +   Q           I+AR+   +  +YD +N  ++ QI
Sbjct  382  AHEVVVFTEQDICSAAEIQSLQFFLHQIKDVFFIIARQEKQNKLIYDTINKYVLDQI  438


>gi|303231923|ref|ZP_07318631.1| CRISPR-associated protein, Csm6 family [Veillonella atypica ACS-049-V-Sch6]
 gi|302513352|gb|EFL55386.1| CRISPR-associated protein, Csm6 family [Veillonella atypica ACS-049-V-Sch6]
Length=439

 Score =  101 bits (252),  Expect = 2e-19, Method: Compositional matrix adjust.
 Identities = 102/417 (25%), Positives = 184/417 (45%), Gaps = 54/417 (12%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            +L LS ++   E A+ R++ A+  +  + D+ ++      VHR D   P F +H  E+ +
Sbjct  35   ILVLSKDMEKKEAANHRFTKALKHVKADLDITLIHTGLEDVHRIDTLQP-FVDHFYEMLS  93

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
             +PD  IL+N SSGTP M+  +  ++V        +QV +P R  S   +    D  D++
Sbjct  94   NYPDAEILINLSSGTPQMKLIMSYLSVEH-DAVRGIQVDSPQRG-SNRSEAAVHDDEDID  151

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQ----LIVSYDYSAAVTIAADSR--  174
            ++ + N D+Q  + NRC E         ++R N+KQ    LI SY Y  A++     +  
Sbjct  152  IVIENNFDDQEDSENRCHEPQM----GYIKRNNIKQSLHTLITSYKYKEAISAYHSYKRS  207

Query  175  LPDQVSNLI---------------RGAMHRSRLEHLVAPKFFKDTAFTYDPANKVAEYIS  219
              D V+N +                GA+ +SR    ++      + F      K+ E++ 
Sbjct  208  FEDGVANDVLPLLEHAQLRLGLDYDGALQKSRKVGSISLS----SLFANKEVRKLHEFLM  263

Query  220  ALALLAKREQWAEFARSATPAITIVLRAAVAKHLPED-RYLDDMG----RVDRRKLERE-  273
             + +  K+ Q  +F    TP +  ++R    K L  + R ++       R+D    E++ 
Sbjct  264  LMEVRLKQGQIEDFILKTTPFMYELIRYYFTKELHVNWRQIEKKTSKGIRLDMVAFEKQY  323

Query  274  PEIRCALKHPPKSPN-AEWYLYTKDWLALLRQFAPDRVGA-----LEVLGRFESRVRNTA  327
            P++  + K    +P   E  L     L +L +   D V +     L+ + R E ++RN  
Sbjct  324  PKLYKSWKANTHTPFLQELQLSFYHMLHMLEE--QDIVDSLLLKQLKEIRRIEQKIRNKM  381

Query  328  AHEIVSISEDRITKDGGLLPEQ--------LLKILARETGADLTLYDRLNDEIIRQI  376
            AHE+V  +E  I K   +   Q        +  I+  +   +  +YD +N  ++ QI
Sbjct  382  AHEVVVFTEQDICKAAEIQSLQSFLHQIKDVFFIITGQAKQNKLIYDVINQYVLEQI  438


>gi|334126725|ref|ZP_08500673.1| hypothetical protein HMPREF9081_0260 [Centipeda periodontii DSM 
2778]
 gi|333391135|gb|EGK62256.1| hypothetical protein HMPREF9081_0260 [Centipeda periodontii DSM 
2778]
Length=452

 Score =  100 bits (249),  Expect = 4e-19, Method: Compositional matrix adjust.
 Identities = 103/380 (28%), Positives = 172/380 (46%), Gaps = 28/380 (7%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VLF + ++A  E+ D RY+ AI R A +  +  +       H ++ F  +    ++ L +
Sbjct  45   VLFYTQDMAEKEHRDHRYTRAIHRTAFDCVIEEIFTDIQEAHLYESFSQILPQEVLRLRS  104

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            E     ILLN SSGTP M+  L A+    +     +QV+ P+R  S   +  + DA D++
Sbjct  105  ENQGAQILLNLSSGTPQMKTVL-AMLAADMENCVGIQVAAPSRT-SNRANEATQDAEDID  162

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRL-PDQV  179
             + + N D + GA NRC E          ER+ ++ LI SY+Y+AA+ IA  S L P + 
Sbjct  163  ALLENNFDEEEGAENRCDEPPLGIFRYYAERSRIRSLIESYEYAAALKIARRSPLVPPEA  222

Query  180  SNLIRGAMHRSRLEHLVAPKFFKD----TAFTY-DPANKVAEYISALALLAKREQWAEFA  234
            S L+  A  RS L    A    ++      F +     ++ EY   + +  +  + +   
Sbjct  223  SLLLSHAEQRSMLLTEEAKAILREYRGKKLFPFIGKTEELVEYFLMMQIDQETGRLSNLM  282

Query  235  RSATPAITIVLRAAVAKHLP-------EDRYLDDMGRVDRRKL-EREPEIRCALKHP---  283
                P +   LR   AK+L        E R  + +  + R +L  +E E+  AL+     
Sbjct  283  LRMIPFLYEFLREYTAKNLTIPIRALCEPR--NGVRCLARERLAAQEKELLAALEREFPY  340

Query  284  --PKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFES-----RVRNTAAHEIVSISE  336
                 P + + L      A   Q   D     EV+   ES     ++RN AAHE+V+++E
Sbjct  341  GYRDQPLSFYLLSLCCAYAGKAQRVRDADLHAEVMAELESIADIRKLRNEAAHEMVNVTE  400

Query  337  DRITKDGGLLPEQLLKILAR  356
            +R  +  G+  +++L    R
Sbjct  401  ERFRQKIGMGSQEVLSCFCR  420


>gi|342213924|ref|ZP_08706637.1| putative CRISPR type III-A/MTUBE-associated protein Csm6 [Veillonella 
sp. oral taxon 780 str. F0422]
 gi|341596422|gb|EGS39024.1| putative CRISPR type III-A/MTUBE-associated protein Csm6 [Veillonella 
sp. oral taxon 780 str. F0422]
Length=449

 Score = 98.6 bits (244),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 93/372 (25%), Positives = 166/372 (45%), Gaps = 40/372 (10%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VLFLS E+   E  +++Y+ AI+ + P+  VR++      VH+ D    +  +    L  
Sbjct  35   VLFLSKEMVVEEERNQQYTKAISYVNPQCVVRLIKTELQEVHKIDALYSLV-DEFYRLKD  93

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            EF +   L+N +SGTP M   +  + +      T VQV TP    S   +       +++
Sbjct  94   EFSEAEFLINLTSGTPQMCQLMTYLAIENTD-VTGVQVDTPTER-SNRTEHALQGNEEID  151

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVS----YDYSAAVTIAADSRL-  175
             + + N DN+ G  NRC E     L  +++R  LK+  +S    Y+Y  A+    + ++ 
Sbjct  152  YVIECNFDNERGTKNRCHE----PLLQIVKRRFLKERCISLVKVYEYKQALQALKEYKML  207

Query  176  --------PDQVSNLIRGAMHRSRLEH----LVAPKFFKDTAFTYDPANKV-----AEYI  218
                     D +  L++ +M+RS  E+       PK  K T     P++K+      EY+
Sbjct  208  AEEEDKEYLDVIGKLLQHSMYRSAFEYDTSLTYIPKELKQTLTHSMPSSKIDIRNLIEYL  267

Query  219  SALALLAKREQWAEFARSATPAITIVLRAAVA-KHLPEDRYLDDMGR---VDRRKLERE-  273
                +  ++  + +F    TP +   ++  +   +    R ++  GR   VDR KL +E 
Sbjct  268  YIAQIRIEKGMYQDFIVKLTPYLFQFMKCILKDTYRVNFRNIEVRGRRGMVDRLKLSKEY  327

Query  274  PEIRCALKHPPKSPNAEWYLYTKDWLALLR--QFAPDR----VGALEVLGRFESRVRNTA  327
            PE+  + +      N +   +   +  +L   QF  D     V +L++       VRN  
Sbjct  328  PELYKSWERSMNQLNYDTKDFELSFFHMLNMIQFHSDTRSDLVNSLKIFTPILKNVRNIV  387

Query  328  AHEIVSISEDRI  339
            AHEI +I+++ I
Sbjct  388  AHEIATITQEDI  399


>gi|258645681|ref|ZP_05733150.1| CRISPR-associated protein, Csm6 family [Dialister invisus DSM 
15470]
 gi|260403049|gb|EEW96596.1| CRISPR-associated protein, Csm6 family [Dialister invisus DSM 
15470]
Length=454

 Score = 97.1 bits (240),  Expect = 5e-18, Method: Compositional matrix adjust.
 Identities = 84/290 (29%), Positives = 131/290 (46%), Gaps = 22/290 (7%)

Query  2    LFLSAEIAAFENADRRYSAAITRLAPETDVRIV--TYTNPSVH-RFDLFVPVFRNHLVEL  58
            +FL+ E+   E     Y+  I ++AP+  +  +    T P ++ R  +   VF     E 
Sbjct  37   VFLTKEMEDKEAESECYTKGIQKVAPQCKIEFIRSGITEPHIYERLTVLQDVFH----EK  92

Query  59   SAEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARAL-SKPGDRESPDAY  117
              ++PD   LLN SSGTP ++  +  I +   P T A+QV TP ++  SK    E+P   
Sbjct  93   YEQYPDEEWLLNLSSGTPQIKTVMGLIGL-DYPETKAIQVLTPGKSSNSKNHPEETPGLV  151

Query  118  DLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSR--L  175
            +   M D NDDN P APNRC EA  + L     +  +  L+ +Y+Y  A+ +   +R   
Sbjct  152  E---MLDCNDDNDPAAPNRCKEAKLSLLKKHSVKWQIISLVENYEYEGALQLLRQNRHLF  208

Query  176  PDQVSNLIRGAMHRSRLEHLVAPKFFKDTAFTYDP----ANKVAEYISALALLAKREQWA  231
             D    L+R A+ R  L    A K     ++   P    A    E+   + L  +++Q  
Sbjct  209  SDISEKLLRHAVCRRNLMWKDANKII--PSYNGKPLISKAGDFEEFFRVMELRQRKKQLY  266

Query  232  EFARSATPAITIVLRAAVAKHLPEDRYLDDMGRVDRRKLEREPEIRCALK  281
            EF    TP I   L    A  L E R L D+      + + + ++R  LK
Sbjct  267  EFIVKTTP-ICTKLATDYAISL-EQRTLFDLNACSEIRRDEDGDVRYVLK  314


>gi|312899100|ref|ZP_07758478.1| CRISPR-associated protein, Csm6 family [Megasphaera micronuciformis 
F0359]
 gi|310619767|gb|EFQ03349.1| CRISPR-associated protein, Csm6 family [Megasphaera micronuciformis 
F0359]
Length=446

 Score = 94.7 bits (234),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 107/418 (26%), Positives = 172/418 (42%), Gaps = 55/418 (13%)

Query  2    LFLSAEIAAFENADRRYSAAITRLAPETDVRIVT--YTNPSVHRFDLFVPVFRNHLVELS  59
            +FL+A++   E     YS  + ++AP+ ++  +    T P  +   L++   +    EL 
Sbjct  36   IFLTADMEEKEEQWHCYSLGVKKVAPQCEIEFIKSGITEPQNYEKLLYL---QEKFDELF  92

Query  60   AEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDL  119
             +FPD   +LN +SGT  MQ  +  ++V   P  TAVQVS P     K       + Y  
Sbjct  93   EQFPDVKWILNITSGTSQMQTIMSFLSV-DYPSCTAVQVSNPHVDRDKVAVHCEKEEY--  149

Query  120  ELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSR--LPD  177
              M + N+D+ P +PNRC E     +   + R  ++ L+ +Y+Y  A+ +   +R    D
Sbjct  150  VQMLECNEDDDPSSPNRCTEPPLLMIRRHVLRFQIESLVRNYEYGGALQLVEQNRRLFSD  209

Query  178  QVSNLIRGAMHRSRLEHLVAPKFFKD---TAFTYDPANKVAEYISALALLAKREQWAEFA  234
                L+R  + R+ L    A K   D         P +  +EY   + L  ++ Q +EF 
Sbjct  210  TTERLLRHGVCRTMLNWREANKIISDYEGNILMQSPGD-FSEYFQVMELRQRKGQLSEFI  268

Query  235  RSATPAITIVLRAAVAKHLPEDRYLD--DMGRVDRRKLER------------EPEIRCAL  280
               +P    VL     K+L   +  D    GR   R  ER             PE++  L
Sbjct  269  VKLSP----VLMGLGFKYLECIKGFDLLQCGRELDRNGERVFIWDCNKARKYNPELQDYL  324

Query  281  KHPPKSPNAEWYLYTKDWLALLRQFAPDRVG----------ALEVLGRFESRVRNTAAHE  330
                     +  LY +  +AL   +    +           A   L   E   RN  AH 
Sbjct  325  DKKYSGDMKDGPLYFQTIMALCEYYKATTLKSDALHNEITTAFSKLRTVEETARNPIAHN  384

Query  331  IVSISEDRI---TKDGGLLPEQ---LLKILARETGADLT------LYDRLNDEIIRQI  376
            I +++E R+   TK   L P     +L+IL R+   D+        YD LND I+  +
Sbjct  385  ICNMTETRLEEETKKQLLEPLNSAGILRIL-RKVYKDIYKKNMAWTYDGLNDCIVESL  441


>gi|114567261|ref|YP_754415.1| hypothetical protein Swol_1746 [Syntrophomonas wolfei subsp. 
wolfei str. Goettingen]
 gi|114338196|gb|ABI69044.1| hypothetical protein Swol_1746 [Syntrophomonas wolfei subsp. 
wolfei str. Goettingen]
Length=413

 Score = 88.6 bits (218),  Expect = 1e-15, Method: Compositional matrix adjust.
 Identities = 95/352 (27%), Positives = 157/352 (45%), Gaps = 38/352 (10%)

Query  30   DVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAINVFG  89
            ++R     NP   +FD+F PVF   L+++    P   IL+N SSGTP M++A   + +  
Sbjct  34   ELRYEEIDNP--QQFDIFYPVFEKELIDIHNANPGCEILINLSSGTPQMKSACHLLALTT  91

Query  90   IPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDDNQP--GAPNRCFEATSAALGA  147
                  +QV+TP  +     +      YDLE  W  N DN P  G  NR     S  L  
Sbjct  92   PFPVIPIQVTTPNES-----ENYGSANYDLETSWKNNLDNDPELGTNNRTQLVESDNLRY  146

Query  148  LLERANLKQLIVSYDYSAAVTIAAD--SRLPDQVSNLIRGAMHRSRLEHLVAPKFFKDTA  205
            L  R      I +++YS+A+ I A     +P+ V +L+  A HR  ++   A K  +   
Sbjct  147  LFLREAAISNINAFNYSSALAILASVAEFVPEDVIHLLMAAQHRKNMDLREAKKRSRLAN  206

Query  206  FTYDP-----ANKVAEYISALALLAKREQWAEFARSATPAIT----IVLRAAVAKHLPED  256
            +   P     A ++ EY+  L L     Q  +F R  +PA++      LR    + +  D
Sbjct  207  YDLFPVKSGDAQELFEYLLLLDLQQNSGQLMDFVRGISPALSRLFECFLREKCQRQVKLD  266

Query  257  -----RYLDDMGRVDRRKL-EREPEIRCA--LKHPPKSPNAEWYLYTKDWLALLR-----  303
                 R+  D   + R KL E++P + C   L+ P    +++  L     L ++      
Sbjct  267  YCVNKRHEPDHYWLKRDKLAEKDPSLLCYYDLRFPNGFRDSD--LSCSTLLPMIEFDCRP  324

Query  304  --QFAPDRV-GALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLK  352
              +F  ++V    + +   E ++RN AAH IV++ E +  +  G+    L+K
Sbjct  325  GGRFPNEKVLLKAQYMRSVEEKIRNPAAHNIVAVKEKQFMQLVGISSASLVK  376


>gi|229826475|ref|ZP_04452544.1| hypothetical protein GCWU000182_01848 [Abiotrophia defectiva 
ATCC 49176]
 gi|229789345|gb|EEP25459.1| hypothetical protein GCWU000182_01848 [Abiotrophia defectiva 
ATCC 49176]
Length=450

 Score = 88.6 bits (218),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 104/419 (25%), Positives = 189/419 (46%), Gaps = 51/419 (12%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAP--ETDVRIVTYTNPS---VHRFDLFVPVFRNHL  55
            +L++S E+   +  D RY   I +L     T   I     P    V+ FD F   F+  L
Sbjct  37   ILYISNEMLENQEKDDRYRYCIRQLDKFASTSTEIAVIERPDLKDVNDFDYFYKDFKEIL  96

Query  56   VELSAEF-PDRTILLNTSSGTPAMQAALVAIN-VFGIPRTTAVQVSTPARALSKPGDRES  113
             +       D  +L+N SSGTP M++ L  +  +        +QVSTP +   +  +  +
Sbjct  97   DKYVKTLNEDDELLINISSGTPQMKSGLAVLQTMLEYSNCKLIQVSTPEK---RSNEHYT  153

Query  114  PDAYDLELMWDA--NDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAA  171
                ++E +W+     +      NRC E    +L  +     +K+ I++YDY+AA++IA 
Sbjct  154  SSDENIEELWNIYIEYNGVESFENRCKEVIFPSLSTIKMEEIIKKHILAYDYAAALSIAE  213

Query  172  DSRLPDQVS----NLIRGAMHRSRLEHLVAPKFFK-DTAFTYDPANK-----VAEYISAL  221
            +  LP + +    +L+R A  R +L  +        +    + P  K     + EY  AL
Sbjct  214  E--LPKESTESYIHLLRYAKARLQLNEIDVNNIKSANNECDFLPVKKSEQRKIVEYTLAL  271

Query  222  ALLAKREQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGRVDRRKLE-REPEIRCAL  280
             +  KRE++A+F R+ TP + + L A + K+  E   L+    +++ +      +I   +
Sbjct  272  DVKRKREEYADFLRAITPLL-VELFANILKNCFEID-LNPYTEIEKGEFRWNGTKISEDI  329

Query  281  KHPPKSPNAEWYL------YTKDWLALLRQFAPDR-------VGALEVLGRFESRVRNTA  327
            +   K  N + Y        T   L  + +  P +          +++L   E  +RN A
Sbjct  330  EQTLKDGNIDLYKNSFKPSVTSFHLYTIMKNLPKKNDNMRKAFEIIDILRAVEQNIRNKA  389

Query  328  AHEIVSISEDRITKDGGLLPEQLLKILARE--TGADLTL--------YDRLNDEIIRQI  376
            AH++VS+++ +I K   +  E ++K + RE  T +D+ +        Y+ +ND II +I
Sbjct  390  AHQMVSVTDAKIEKITDMNAEGIMKKI-RELFTYSDINIPKQGGWNSYELMNDSIIAKI  447


>gi|333976325|gb|EGL77194.1| CRISPR-associated protein, Csm6 family [Veillonella parvula ACS-068-V-Sch12]
Length=439

 Score = 85.9 bits (211),  Expect = 1e-14, Method: Compositional matrix adjust.
 Identities = 102/425 (24%), Positives = 179/425 (43%), Gaps = 70/425 (16%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            +L LS ++   E +D R+S A+  +  + D++++      VHR D   P F +H  E+ +
Sbjct  35   ILVLSKDMEQKEASDSRFSKALKHVKADLDIKLIHTGLEDVHRIDTLQP-FVDHFYEMLS  93

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            ++PD  IL+N SSGTP M+  +  ++V        +QV +P        +R  P   D E
Sbjct  94   KYPDAEILINLSSGTPQMKLIMSYLSVEH-DAVRGIQVDSPQGG----SNRSEPAVNDDE  148

Query  121  LMWDAND---DNQPGAPNRCFEATSAALGALLERANLKQ----LIVSYDYSAAVTIA---  170
             +    +   D+Q G  NRC E         ++R NLKQ    LI SY Y  A+++    
Sbjct  149  DIEIIIENNLDDQEGTENRCHEPQM----GYIKRNNLKQSLHTLINSYKYKEAISLYHGY  204

Query  171  ----ADSRLPDQVSNLIRGAMHRSRLEHLVAPKFFKDTA-------FTYDPANKVAEYIS  219
                 D  + D V  L+  A  R  L++  A +  +          FT     K+ E++ 
Sbjct  205  KRTFKDGVVID-VLPLLEHAQLRLGLDYDSALQKSRKVGSINLSSIFTDKVLRKLHEFLM  263

Query  220  ALALLAKREQWAEFARSATPAITIVLRAAVAKHLPEDRYLDDMGRVDRRKLERE------  273
             + +  K+ Q  +F    TP +  ++R    K             V+ R++E++      
Sbjct  264  LMEVRLKQGQIEDFILKTTPFMYELMRYYFTKEFS----------VNWRQVEKKTSKGVR  313

Query  274  ----------PEIRCALKHPPKSPN-AEWYLYTKDWLALLRQF-APDR--VGALEVLGRF  319
                      P++  + +    +P   E  +     L +L  +   DR  +  L+ + R 
Sbjct  314  LDMVAFKNQYPKLYESWQENSDTPYLKELQVSFYHMLHMLENYDTVDRSLLKQLKEIRRI  373

Query  320  ESRVRNTAAHEIVSISEDRITKDGGLLPEQ--------LLKILARETGADLTLYDRLNDE  371
            E ++RN  AHEIV  +E  I     +   Q        +  I+  +   +  +YD +N  
Sbjct  374  EQKIRNKMAHEIVVFTERDICSAAEIQSLQSFLHQIKDVFFIITGQEKQNKLIYDTINTY  433

Query  372  IIRQI  376
            ++ QI
Sbjct  434  VLEQI  438


>gi|322387549|ref|ZP_08061158.1| hypothetical protein HMPREF9423_0556 [Streptococcus infantis 
ATCC 700779]
 gi|321141416|gb|EFX36912.1| hypothetical protein HMPREF9423_0556 [Streptococcus infantis 
ATCC 700779]
Length=429

 Score = 73.2 bits (178),  Expect = 7e-11, Method: Compositional matrix adjust.
 Identities = 66/268 (25%), Positives = 115/268 (43%), Gaps = 25/268 (9%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VL  S E+   ++   +   +I    P+  +  +   N  V+ FD    V    + + S 
Sbjct  35   VLVYSEEMLVKKDLVEKALCSIEGYHPKVVIESIILKNDEVYLFDKMYEVMGQIIEKYSG  94

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSK---PGDRESPDAY  117
               D  ++LN SSGTP + +AL A+N      T A+QV+TP ++ ++   P   E     
Sbjct  95   --TDHQLILNLSSGTPQIISALFALNRINDYNTQAIQVATPNKSANRKYVPLSNE-----  147

Query  118  DLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPD  177
            D + ++D N+DNQ    +R  +  +      L + +L+ LI SYDY     +AA+  +  
Sbjct  148  DEQKLFDENEDNQKDYEDRTIKDEAEKFNQSLIKRHLRNLISSYDY-----LAAEELVTR  202

Query  178  QVSNLIRGAMHRSRLEHLVAP--KFFKDTAFTYD--------PANKVAEYISALALLAKR  227
            +  N +      +RL  L+    K FK  A   D           K   Y   + +L +R
Sbjct  203  KEYNKLLSKKKLARLRDLLNDFVKVFKTQAILKDIQGYSLTEVEKKALNYFLMIEVLKER  262

Query  228  EQWAEFARSATPAITIVLRAAVAKHLPE  255
             Q A+    +   +  ++   + K  P+
Sbjct  263  GQVADVLIKSKSYVEFIIEEKIKKDYPD  290


>gi|322375481|ref|ZP_08049994.1| CRISPR-associated protein, Csm6 family [Streptococcus sp. C300]
 gi|321279744|gb|EFX56784.1| CRISPR-associated protein, Csm6 family [Streptococcus sp. C300]
Length=407

 Score = 71.2 bits (173),  Expect = 3e-10, Method: Compositional matrix adjust.
 Identities = 83/356 (24%), Positives = 145/356 (41%), Gaps = 31/356 (8%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VL  S E+   +    R   +     P+  +      N  V+ +D    +    + E S 
Sbjct  13   VLLYSEEMLVKKTLIERALLSFKDYKPDVKIHEQILRNDEVYLYDKMYEIIGKIIKEYSK  72

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
                  ++LN SSGTP +++AL AIN      T A+QV+TP+ + + P    S +  D  
Sbjct  73   --LGEELILNLSSGTPQIKSALFAINRIDDYNTQAIQVTTPSNSSNNPQKILSKEEED--  128

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAA--VTIAADSRLPDQ  178
             ++  N+DNQ    NRC    +      L + +L+ LI SYDY A   + I  DS+    
Sbjct  129  NLFKNNEDNQDNYENRCIMDIAEKFNHSLVKRHLRSLIESYDYLAVEKIVIRRDSKGLLS  188

Query  179  VSNLIRGAMHRSRLEHLVAPKFFKDTAFTY---DPANKVAEYISALALLAKREQWAEFAR  235
               L R  +  + L ++   +        Y   +   K   Y   + +L KR Q A+   
Sbjct  189  NKQLARLRIILTDLVNVFKKQEVLSEIQKYPLSEVEKKALNYFLMIEILNKRGQVADVLI  248

Query  236  SATPAITIVLRAAVAKHLPE-----------DRYLDDMGRV------DRRKLEREPEIRC  278
             +   +  +L   + ++ P            ++   D  +V      D +K + E E + 
Sbjct  249  KSKSLVEFILEDRIKRNHPNLIIYKNKLPKLNKEHQDFEKVIGYLDSDYKKSQNENEGKK  308

Query  279  ALKHPPKSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSI  334
                P  + N    +YTK  +    +++P+ + +L V+    +  RN  AH +  I
Sbjct  309  EDFSPTTTLN--LIIYTK--ILEYYKYSPELIKSLRVIISLNNE-RNKVAHGLSEI  359


>gi|270292491|ref|ZP_06198702.1| conserved hypothetical protein [Streptococcus sp. M143]
 gi|270278470|gb|EFA24316.1| conserved hypothetical protein [Streptococcus sp. M143]
Length=349

 Score = 70.1 bits (170),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 72/290 (25%), Positives = 125/290 (44%), Gaps = 29/290 (10%)

Query  67   ILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDAN  126
            ++LN SSGTP +++AL AIN      T A+QV+TP+ + + P    S +  D   ++  N
Sbjct  19   LILNLSSGTPQIKSALFAINRIDDYNTQAIQVTTPSNSSNNPQKILSKEEED--NLFKNN  76

Query  127  DDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAA--VTIAADSRLPDQVSNLIR  184
            +DNQ    NRC    +      L + +L+ LI SYDY A   + I  DS+       L R
Sbjct  77   EDNQDNYENRCIMDIAEKFNHSLVKRHLRSLIESYDYLAVEKIVIRRDSKGLLSNKQLAR  136

Query  185  GAMHRSRLEHLVAPKFFKDTAFTY---DPANKVAEYISALALLAKREQWAEFARSATPAI  241
              +  + L ++   +        Y   +   K   Y   + +L KR Q A+    +   +
Sbjct  137  LRIILTDLVNVFKKQEVLSEIQKYPLSEVEKKALNYFLMIEILNKRGQVADVLIKSKSLV  196

Query  242  TIVLRAAVAKHLPE-----------DRYLDDMGRV------DRRKLEREPEIRCALKHPP  284
              +L   + ++ P            ++   D  +V      D +K + E E +     P 
Sbjct  197  EFILEDRIKRNHPNLIIYKNKLPKLNKEHQDFEKVIGYLDSDYKKSQNENEGKKEDFSPT  256

Query  285  KSPNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSI  334
             + N    +YTK  +    +++P+ + +L V+    +  RN  AH +  I
Sbjct  257  TTLN--LIIYTK--ILEYYKYSPELIKSLRVIISLNNE-RNKVAHGLSEI  301


>gi|315641548|ref|ZP_07896617.1| csm6 family CRISPR-associated protein [Enterococcus italicus 
DSM 15952]
 gi|315482685|gb|EFU73212.1| csm6 family CRISPR-associated protein [Enterococcus italicus 
DSM 15952]
Length=430

 Score = 67.0 bits (162),  Expect = 5e-09, Method: Compositional matrix adjust.
 Identities = 51/218 (24%), Positives = 95/218 (44%), Gaps = 15/218 (6%)

Query  44   FDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPAR  103
            FD +  +F  +LVE   ++P+  I LN +SGTP M+  L    V    +   +QVSTP +
Sbjct  83   FDAYKDLFHQYLVEEKRKYPNAEIFLNVTSGTPQMETTLCLEYVTYPDKMRCIQVSTPLK  142

Query  104  ALSKPGDRESPDAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDY  163
              +        D  +++L  +  ++ +   P+RC +    +    + R  +K L+ +YDY
Sbjct  143  TSNAKTKYAQADCQEVDL--EIVNEEESQQPSRCHKIAILSFREAIVRNQIKSLLDNYDY  200

Query  164  SAAVTIAADSRLPDQVSNLIRGAMHRSRLEHLV----APKFFKDTAFTYDPANKVAEYIS  219
             AA+ + A  +      +   G   R +L+ L+      + F      Y    K+ + + 
Sbjct  201  EAALQLVASQK------SFRNGKEIRKKLKELIDDIKMHRVFSYLIKQYPRNEKLQKALL  254

Query  220  ALALLAKREQWAEFARSATPAITI---VLRAAVAKHLP  254
               LL  R Q  + A +     +I   ++   + K+ P
Sbjct  255  HTILLEMRHQRGDIAETLIRVKSIAEYIVEQYIQKNYP  292


>gi|322387548|ref|ZP_08061157.1| hypothetical protein HMPREF9423_0555 [Streptococcus infantis 
ATCC 700779]
 gi|321141415|gb|EFX36911.1| hypothetical protein HMPREF9423_0555 [Streptococcus infantis 
ATCC 700779]
Length=386

 Score = 64.3 bits (155),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 89/391 (23%), Positives = 155/391 (40%), Gaps = 62/391 (15%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            ++F    I+  ++ ++   +  T   PE         N  V  FD     F   + +   
Sbjct  36   IVFSERTISKKDDIEKVIHSIDTEYLPEIVCHEPIILNEDVFVFDTMYEQFDAIIQKYYT  95

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            +  D   +LN SS TP +++AL  IN        AVQVS+P    S  G     D+ D++
Sbjct  96   K--DDGFILNLSSATPQVKSALFVINRLSEINVKAVQVSSPEND-SNAG-VGHDDSEDID  151

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
             + D N DN+    +R  E TS      L +  L+  I  YDY A++ +A      +Q+S
Sbjct  152  ALIDTNLDNKQDYIDRTIEDTSEKFKQGLMKKTLRDFITKYDYKASLEVA------NQLS  205

Query  181  NLIRGAMHRSRLEHLV-------APKFFKDTAFTYDPANKVAEYISALALLAKREQWAEF  233
            +       R +L+ +V        P+  +   ++ +    +  Y++ + L  +R  ++E 
Sbjct  206  DFPGLKECRKKLQDIVDSLDRQAVPQVLQKKKWSEEQKKVLNSYLT-IDLQKERGNFSEG  264

Query  234  ARSATPAITIVLRAAVAKHLPE--DRYLDD-----MGRVDRRKLEREPEIRCALKHPPKS  286
                      +L   +    P   D Y +D     +G  D  K+ +E             
Sbjct  265  LIRIKNLTEFILDDYIENRYPGFLDNYANDSEKYYIGIWDYGKILQEKR-----------  313

Query  287  PNAEWYLYTKDWLALLRQFAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLL  346
               EW L+ K    +LR                 ++ RNT AH++ S+  + + + G +L
Sbjct  314  ---EWTLHNK-IKPILRM----------------NKTRNTIAHKLDSLDSEELKQLGPVL  353

Query  347  PEQLLKILARE----TGADLTLYDRLNDEII  373
              + LK L +E    T  D   Y   N E++
Sbjct  354  --KALKGLIKEQYQLTEKDFNFYKDFNKELL  382


>gi|57865879|ref|YP_189999.1| hypothetical protein SERP2456 [Staphylococcus epidermidis RP62A]
 gi|57636537|gb|AAW53325.1| hypothetical protein SERP2456 [Staphylococcus epidermidis RP62A]
Length=422

 Score = 63.2 bits (152),  Expect = 7e-08, Method: Compositional matrix adjust.
 Identities = 39/163 (24%), Positives = 74/163 (46%), Gaps = 14/163 (8%)

Query  18   YSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPA  77
            +   I  ++P T+V I+     +   +D+F   F  +L  +   + D  I+LN +SGTP 
Sbjct  57   WEKIIQTVSPNTEVEIIIENVDNAQDYDVFKEKFHKYLKIIEDSYEDCEIILNVTSGTPQ  116

Query  78   MQAALVAINVFGIPRTTAVQVSTPAR------ALSKPGDRESPDAYDLELMWDANDDNQP  131
            M++ L    +        VQVSTP +        S P D+      + E++    ++ + 
Sbjct  117  MESTLCLEYIVYPENKKCVQVSTPTKDSNAGIEYSNPKDK----VEEFEIV----NEVEK  168

Query  132  GAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSR  174
             +  RC E    +    + R+ +  LI +YDY  A+ + ++ +
Sbjct  169  KSEKRCKEINILSFREAMIRSQILGLIDNYDYEGALNLVSNQK  211


>gi|329736405|gb|EGG72674.1| CRISPR-associated protein, Csm6 family [Staphylococcus epidermidis 
VCU045]
 gi|341656707|gb|EGS80416.1| CRISPR-associated protein, Csm6 family [Staphylococcus epidermidis 
VCU037]
Length=422

 Score = 62.8 bits (151),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 38/163 (24%), Positives = 74/163 (46%), Gaps = 14/163 (8%)

Query  18   YSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPA  77
            +   I  ++P T+V I+     +   +D+F   F  +L  +   + D  I+LN +SGTP 
Sbjct  57   WEKIIQTVSPNTEVEIIIENVDNAQDYDVFKEKFHKYLKIIEDSYEDCEIILNVTSGTPQ  116

Query  78   MQAALVAINVFGIPRTTAVQVSTPAR------ALSKPGDRESPDAYDLELMWDANDDNQP  131
            M++ L    +        +QVSTP +        S P D+      + E++    ++ + 
Sbjct  117  MESTLCLEYIVYPENKKCIQVSTPTKDSNAGIEYSNPKDK----VEEFEIV----NEVEK  168

Query  132  GAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSR  174
             +  RC E    +    + R+ +  LI +YDY  A+ + ++ +
Sbjct  169  KSEKRCKEINILSFREAMIRSQILGLIDNYDYEGALNLVSNQK  211


>gi|289549404|ref|YP_003470308.1| CRISPR-associated protein Csm6 [Staphylococcus lugdunensis HKU09-01]
 gi|289178936|gb|ADC86181.1| CRISPR-associated protein Csm6 [Staphylococcus lugdunensis HKU09-01]
Length=225

 Score = 59.3 bits (142),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 39/156 (25%), Positives = 73/156 (47%), Gaps = 6/156 (3%)

Query  18   YSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPA  77
            +   +++++P+T V I        H FD +  +F   +  +    P+  ILLN +SGTP 
Sbjct  57   WEKIVSKVSPQTSVEIKVENIEHEHDFDSYKDLFSYFIKGIRMSNPESEILLNVTSGTPQ  116

Query  78   MQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDA--YDLELMWDANDDNQPGAPN  135
            M++ L    +        +QVS P  + +      +P+    DLE +    + N+  A N
Sbjct  117  MESTLCLEYISNPNNAQCIQVSAPQPSNNTKRLYANPNNAFKDLEKV----NQNEHLADN  172

Query  136  RCFEATSAALGALLERANLKQLIVSYDYSAAVTIAA  171
            RC      +   ++ R+ ++ LI +YDY  A+ + +
Sbjct  173  RCKSINILSFREVMVRSQVRGLIDNYDYEGALNLIS  208


>gi|312278327|gb|ADQ62984.1| Putative uncharacterized protein [Streptococcus thermophilus 
ND03]
Length=391

 Score = 57.4 bits (137),  Expect = 4e-06, Method: Compositional matrix adjust.
 Identities = 41/143 (29%), Positives = 68/143 (48%), Gaps = 4/143 (2%)

Query  27   PETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAIN  86
            PE  +  +  ++  VH FD+    F + L E   +  +   +LN SS TP +++AL  IN
Sbjct  10   PELIIHDLIISDNEVHIFDVMFQRFSDILQEYYTK--EDEFILNLSSATPQIKSALFVIN  67

Query  87   VFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDDNQPGAPNRCFEATSAALG  146
                    AV+VS+P  A +K    ++ +  D EL+   N+DN+    +R  E  +    
Sbjct  68   RLNGINVKAVKVSSPEHASNKNIGHDNDENID-ELIK-VNEDNKVNFIDRTIEDNAEKFS  125

Query  147  ALLERANLKQLIVSYDYSAAVTI  169
              L +   +  I  +DY AA+ I
Sbjct  126  QALLKKTARDFIEKFDYKAALDI  148


>gi|339278119|emb|CCC19867.1| hypothetical protein STH8232_1168 [Streptococcus thermophilus 
JIM 8232]
Length=428

 Score = 57.0 bits (136),  Expect = 5e-06, Method: Compositional matrix adjust.
 Identities = 65/259 (26%), Positives = 106/259 (41%), Gaps = 15/259 (5%)

Query  1    VLFLSAEIAAFENADRRYSAAITRLAPETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSA  60
            VL  S E+   ++   +   +I    P  ++      N  V  FD    V    + + + 
Sbjct  35   VLVYSQEMMVKQDLINKVLLSIEGYNPIIEIDSTILNNDEVFLFDKMYEVMGQIVQKYTN  94

Query  61   EFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLE  120
            +  D  I+LN SSGTP + +AL A+N      T A+QV+TP    ++     +    D  
Sbjct  95   D--DNEIILNLSSGTPQIISALFALNRINDYNTQAIQVATPKNRANREYTALTESEIDAL  152

Query  121  LMWDANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVS  180
            +M   N DN+    +R  +  S      L + +L+ LI S+DY AA  I         +S
Sbjct  153  IM--ENQDNRLDFVDRSIKDKSEKFTQALVKRHLRSLIASFDYQAAEAIINRKEYNKLLS  210

Query  181  NLIRGAMHRSRLEHLVAPKFFKDT-------AFTYDPANKVA-EYISALALLAKREQWAE  232
               + A  R +L      + FK+        +F  D + K A  Y   + +L +RE  A+
Sbjct  211  KK-KIAYIREKLYDF--SRVFKNQSILSDILSFPLDDSQKKALNYYLMIDVLKEREHIAD  267

Query  233  FARSATPAITIVLRAAVAK  251
                A      V+   + K
Sbjct  268  VLIKAKSLAEFVIEETIKK  286


>gi|334308476|gb|EGL99462.1| CRISPR-associated protein Csm6 [Lactobacillus salivarius NIAS840]
Length=350

 Score = 56.6 bits (135),  Expect = 7e-06, Method: Compositional matrix adjust.
 Identities = 39/139 (29%), Positives = 64/139 (47%), Gaps = 4/139 (2%)

Query  37   TNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAV  96
            ++  V  FD    V    + + S E  D  ++LN SSGTP M++AL  IN        A 
Sbjct  10   SDSEVFIFDKMYEVLNGIISKYSKE--DEDLILNLSSGTPQMKSALFTINRLKDINVKAY  67

Query  97   QVSTPARALSKPGDRESPDAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQ  156
            QV TP+ + S  G +   +  D++ +   N DN+     R  E  +      L +  +K 
Sbjct  68   QVVTPSHS-SNEGIKHDNNL-DIDYLISTNLDNRDDFEKRILEDKAEKFQQTLIKRTMKD  125

Query  157  LIVSYDYSAAVTIAADSRL  175
            L+ S+DY +   ++   R+
Sbjct  126  LLNSFDYESLYNLSKRYRV  144


>gi|339278118|emb|CCC19866.1| hypothetical protein STH8232_1167 [Streptococcus thermophilus 
JIM 8232]
Length=386

 Score = 56.6 bits (135),  Expect = 8e-06, Method: Compositional matrix adjust.
 Identities = 83/369 (23%), Positives = 146/369 (40%), Gaps = 62/369 (16%)

Query  21   AITRLAPETDVRIVTY----TNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTP  76
            A+  +AP  +  ++ +    ++  VH FD+    F + L E   +  +   +LN SS TP
Sbjct  52   ALFSIAPNYEPELIIHDPIISDNEVHIFDVMFQRFSDILQEYYTK--EDEFILNLSSATP  109

Query  77   AMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDDNQPGAPNR  136
             +++AL  IN        AVQVS+P  A ++    ++ +  D EL+ + N DN+    +R
Sbjct  110  QIKSALFVINRLNGINVKAVQVSSPEHASNENIGHDNDENID-ELI-EVNKDNKVNFIDR  167

Query  137  CFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVSNLIRGAMHRSRLEHLV  196
              E  +      L +   +  I  +DY AA+ I       DQ+S+       R  +  +V
Sbjct  168  TIEDNAEKFSQALLKKTARDFIEKFDYKAALDIL------DQLSDFPNLKSVREEIRDVV  221

Query  197  -------APKFFKDTAFTYDPANKVAEYISALALLAKREQWAEFARSATPAITIVLRAAV  249
                    PK  +      +    ++ Y++ + L  +R   +E           +L   +
Sbjct  222  NCLSKQDVPKGLRHKKLKEEEQKILSAYLT-IELQRERGNVSESFIRIKNLTEFILEDYI  280

Query  250  AKHLPE--DRYLDDMGRVDRRKLEREPEIRCALKHPPKSPNAEWYLYTKDWLALL---RQ  304
             K  P   D Y +D+ +                          +YL   D+  LL   ++
Sbjct  281  EKRYPGLIDEYCEDIQK--------------------------YYLSLFDYSKLLKATKE  314

Query  305  FAPDRVGALEVLGRFESRVRNTAAHEIVSISEDRITKDGGLLPEQLLKILARE----TGA  360
            F   R  A  ++    S  RN  AH +  +  D + + G  +  + LK L RE    + +
Sbjct  315  FKLKRTIA-PIIDMNSS--RNKVAHSLSPLDSDAVKQLG--IAMKTLKTLVREQYHFSQS  369

Query  361  DLTLYDRLN  369
            D   Y  LN
Sbjct  370  DFNFYHDLN  378


>gi|227890800|ref|ZP_04008605.1| conserved hypothetical protein [Lactobacillus salivarius ATCC 
11741]
 gi|227867209|gb|EEJ74630.1| conserved hypothetical protein [Lactobacillus salivarius ATCC 
11741]
Length=412

 Score = 55.8 bits (133),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 38/135 (29%), Positives = 62/135 (46%), Gaps = 4/135 (2%)

Query  37   TNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAINVFGIPRTTAV  96
            ++  V  FD    V    + + S E  D  ++LN SSGTP M++AL  IN        A 
Sbjct  71   SDSEVFIFDKMYEVLNGIISKYSKE--DEDLILNLSSGTPQMKSALFTINRLKDINVKAY  128

Query  97   QVSTPARALSKPGDRESPDAYDLELMWDANDDNQPGAPNRCFEATSAALGALLERANLKQ  156
            QV TP+ + S  G +   +  D++ +   N DN+     R  E  +      L +  +K 
Sbjct  129  QVVTPSHS-SNEGIKHDNNL-DIDYLISTNLDNRDDFKKRILEDKAEKFQQTLIKRTMKD  186

Query  157  LIVSYDYSAAVTIAA  171
            L+ S+DY +   ++ 
Sbjct  187  LLNSFDYESLYNLST  201


>gi|325687525|gb|EGD29546.1| hypothetical protein HMPREF9381_1059 [Streptococcus sanguinis 
SK72]
Length=438

 Score = 55.5 bits (132),  Expect = 1e-05, Method: Compositional matrix adjust.
 Identities = 62/258 (25%), Positives = 104/258 (41%), Gaps = 30/258 (11%)

Query  18   YSAAITRLAPETDVRIVT--YTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGT  75
            + AA+  +     V ++   Y    VH FD         L E      D   +LN +SGT
Sbjct  90   FEAAVQAVYDGKKVYVIQNKYVKEGVHEFDTMYKFVEEILDEEDMSHGD--YILNVTSGT  147

Query  76   PAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESP------DAYDLELM-WDANDD  128
            P  QAA+ AIN      T   +V++P    +   ++ +P        Y LE    D  D+
Sbjct  148  PQCQAAMYAINFVKDYHTRLARVNSPRSEKTNQSNQGAPWFETATFKYFLEKQASDYEDN  207

Query  129  NQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQVSNLIRGAMH  188
             Q G      E        LL+R   K  I+ Y+Y AA+ I  ++  PD +S+       
Sbjct  208  RQLG-----IEKGEKFKNNLLQRT-YKNFILKYEYKAALDILKEN--PDIISDKQDQENS  259

Query  189  RSRLEHLVA--------PKFFKDTAFTY---DPANKVAEYISALALLAKREQWAEFARSA  237
            ++ LE++++         +   D+   Y   D   KV  Y   + +L +R Q  +    A
Sbjct  260  KNILENMISVFQKQRVLEELAADSNLKYNNTDEFQKVLNYYLMIDILNRRGQVTDVLVKA  319

Query  238  TPAITIVLRAAVAKHLPE  255
                  +L++ + +  P+
Sbjct  320  KSFAEFILKSVIERRHPD  337


>gi|55822919|ref|YP_141360.1| hypothetical protein str0965 [Streptococcus thermophilus CNRZ1066]
 gi|55738904|gb|AAV62545.1| unknown protein [Streptococcus thermophilus CNRZ1066]
Length=399

 Score = 50.4 bits (119),  Expect = 5e-04, Method: Compositional matrix adjust.
 Identities = 39/143 (28%), Positives = 66/143 (47%), Gaps = 4/143 (2%)

Query  27   PETDVRIVTYTNPSVHRFDLFVPVFRNHLVELSAEFPDRTILLNTSSGTPAMQAALVAIN  86
            PE  +     ++  VH FD+    F + L E   +  +   +LN SS TP +++AL  IN
Sbjct  10   PELIIHDPIISDNEVHIFDVMFQRFSDILQEYYTK--EDEFILNLSSATPQIKSALFVIN  67

Query  87   VFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDDNQPGAPNRCFEATSAALG  146
                    AV+V +P  A ++    ++ +  D EL+   N+DN+    +R  E  +    
Sbjct  68   RLNGINIKAVKVWSPEHASNENIGHDNDENID-ELI-KVNEDNKVNFIDRTIEDNAEKFS  125

Query  147  ALLERANLKQLIVSYDYSAAVTI  169
              L +   +  I  +DY AA+ I
Sbjct  126  QALLKKTARDFIEKFDYKAALDI  148


>gi|55821001|ref|YP_139443.1| hypothetical protein stu0966 [Streptococcus thermophilus LMG 
18311]
 gi|55736986|gb|AAV60628.1| unknown protein, truncated [Streptococcus thermophilus LMG 18311]
Length=342

 Score = 46.6 bits (109),  Expect = 0.007, Method: Compositional matrix adjust.
 Identities = 30/101 (30%), Positives = 50/101 (50%), Gaps = 2/101 (1%)

Query  69   LNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDD  128
            +N SS TP +++AL  IN        AV+VS+P  A ++    ++ +  D EL+   N+D
Sbjct  1    MNLSSATPQIKSALFVINRLNGINVKAVKVSSPEHASNENIGHDNDENID-ELIK-VNED  58

Query  129  NQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTI  169
            N+    +R  E  +      L +   +  I  +DY AA+ I
Sbjct  59   NKVNFIDRTIEDNAEKFSQALLKKTARDFIEKFDYKAALDI  99


>gi|301299687|ref|ZP_07205941.1| putative CRISPR-associated protein, Csm6 family [Lactobacillus 
salivarius ACS-116-V-Col5a]
 gi|300852710|gb|EFK80340.1| putative CRISPR-associated protein, Csm6 family [Lactobacillus 
salivarius ACS-116-V-Col5a]
Length=311

 Score = 44.3 bits (103),  Expect = 0.034, Method: Compositional matrix adjust.
 Identities = 29/107 (28%), Positives = 48/107 (45%), Gaps = 2/107 (1%)

Query  69   LNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWDANDD  128
            +N SSGTP M++AL  IN        A QV TP+ + S  G     +   +  +   N D
Sbjct  1    MNLSSGTPQMKSALFTINRLNDINVRAYQVITPSHS-SNEGIGHDNNL-GINYLISTNLD  58

Query  129  NQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRL  175
            N+     R  E  +      L +  +K L+ ++DY +   ++   R+
Sbjct  59   NRKDFKKRILEDKAEKFQKTLIKRTMKDLLNNFDYESLYNLSIRHRV  105


>gi|325696574|gb|EGD38464.1| hypothetical protein HMPREF9384_1721 [Streptococcus sanguinis 
SK160]
Length=438

 Score = 42.0 bits (97),  Expect = 0.18, Method: Compositional matrix adjust.
 Identities = 48/204 (24%), Positives = 84/204 (42%), Gaps = 30/204 (14%)

Query  68   LLNTSSGTPAMQAALVAINVFGIPRTTAVQVSTPARALSKPGDRESPDAYDLELMWD---  124
            +LN +SGT   QAA+  IN      T   +V +P    +   ++ +P  Y  E++ D   
Sbjct  140  ILNITSGTAQCQAAMYFINFIKDYHTRLARVDSPNGKKTNRSNQGAP--YFEEVVLDDLL  197

Query  125  ------ANDDNQPGAPNRCFEATSAALGALLERANLKQLIVSYDYSAAVTIAADSRLPDQ  178
                    D+ +P       E        LL+R   K  I++Y+Y AA+ I   +  PD 
Sbjct  198  KKQTAECRDERKPE-----IETGEKLKNNLLQRT-YKDFILNYEYKAALDILKAN--PDI  249

Query  179  VSNLIRGAMHRSRLEHLVA----PKFFK----DTAFTYDPA---NKVAEYISALALLAKR  227
            +SN       +  LE++++     K  K    D+   Y+      KV  Y   + +L +R
Sbjct  250  ISNKDDQEKSKKALENMISVFQKQKVLKELAADSKLKYNDTGEFQKVLNYYLMIDILNRR  309

Query  228  EQWAEFARSATPAITIVLRAAVAK  251
             Q  +    A      +L++ + +
Sbjct  310  GQVTDVLVKAKSFAEFILKSVIER  333



Lambda     K      H
   0.320    0.134    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 

Effective search space used: 740471427550


  Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF
excluding environmental samples from WGS projects
    Posted date:  Sep 5, 2011  4:36 AM
  Number of letters in database: 5,219,829,388
  Number of sequences in database:  15,229,318



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40