BLAST Search Results

BLASTP 2.2.25+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects 15,229,318 sequences; 5,219,829,388 total letters Query= Rv2820c Length=302 Score E Sequences producing significant alignments: (Bits) Value gi|15609957|ref|NP_217336.1| hypothetical protein Rv2820c [Mycob... 607 5e-172 gi|289751479|ref|ZP_06510857.1| hypothetical protein TBDG_02577 ... 606 1e-171 gi|340627816|ref|YP_004746268.1| hypothetical protein MCAN_28441... 538 3e-151 gi|323718577|gb|EGB27744.1| csm4 family CRISPR-associated ramp p... 518 4e-145 gi|289571007|ref|ZP_06451234.1| hypothetical protein TBJG_02426 ... 460 1e-127 gi|289746619|ref|ZP_06505997.1| predicted protein [Mycobacterium... 236 4e-60 gi|224543483|ref|ZP_03684022.1| hypothetical protein CATMIT_0269... 225 6e-57 gi|331004040|ref|ZP_08327522.1| csm4 family CRISPR-associated ra... 202 5e-50 gi|253578037|ref|ZP_04855309.1| CRISPR-associated protein [Rumin... 196 3e-48 gi|289549402|ref|YP_003470306.1| CRISPR-associated RAMP protein,... 184 2e-44 gi|240143671|ref|ZP_04742272.1| CRISPR-associated RAMP protein, ... 182 8e-44 gi|291539923|emb|CBL13034.1| CRISPR-associated RAMP protein, Csm... 179 4e-43 gi|229826461|ref|ZP_04452530.1| hypothetical protein GCWU000182_... 178 1e-42 gi|329736407|gb|EGG72676.1| CRISPR-associated RAMP protein, Csm4... 177 2e-42 gi|57865881|ref|YP_190001.1| CRISPR-associated Csm4 family prote... 177 2e-42 gi|291460038|ref|ZP_06599428.1| CRISPR-associated RAMP protein, ... 177 3e-42 gi|315641550|ref|ZP_07896619.1| csm4 family CRISPR-associated ra... 171 1e-40 gi|315925058|ref|ZP_07921275.1| CRISPR-associated Csm4 family pr... 171 1e-40 gi|345284419|gb|AEN78272.1| CRISPR-associated protein, Csm4 fami... 170 3e-40 gi|295105102|emb|CBL02646.1| CRISPR-associated RAMP protein, Csm... 166 4e-39 gi|322387546|ref|ZP_08061155.1| csm4 family CRISPR-associated ra... 165 7e-39 gi|270292489|ref|ZP_06198700.1| conserved hypothetical protein [... 161 1e-37 gi|322375483|ref|ZP_08049996.1| CRISPR-associated RAMP protein, ... 161 1e-37 gi|339278116|emb|CCC19864.1| hypothetical protein STH8232_1165 [... 158 1e-36 gi|312278324|gb|ADQ62981.1| CRISPR-associated protein, Csm4 fami... 158 1e-36 gi|55820998|ref|YP_139440.1| hypothetical protein stu0963 [Strep... 157 2e-36 gi|55822917|ref|YP_141358.1| hypothetical protein str0963 [Strep... 156 3e-36 gi|334308472|gb|EGL99458.1| CRISPR-associated RAMP protein, Csm4... 151 1e-34 gi|227890794|ref|ZP_04008599.1| CRISPR-associated Csm4 family pr... 142 7e-32 gi|125718068|ref|YP_001035201.1| hypothetical protein SSA_1248 [... 140 2e-31 gi|114567268|ref|YP_754422.1| hypothetical protein Swol_1753 [Sy... 140 3e-31 gi|325687527|gb|EGD29548.1| hypothetical protein HMPREF9381_1061... 138 1e-30 gi|327469967|gb|EGF15431.1| hypothetical protein HMPREF9386_0578... 138 1e-30 gi|296133518|ref|YP_003640765.1| CRISPR-associated RAMP protein,... 137 2e-30 gi|225018978|ref|ZP_03708170.1| hypothetical protein CLOSTMETH_0... 134 2e-29 gi|237741577|ref|ZP_04572058.1| CRISPR-associated protein [Fusob... 132 5e-29 gi|294782690|ref|ZP_06748016.1| CRISPR-associated RAMP protein, ... 126 5e-27 gi|340752432|ref|ZP_08689231.1| csm4 family CRISPR-associated ra... 121 1e-25 gi|301299524|ref|ZP_07205793.1| putative CRISPR-associated RAMP ... 120 3e-25 gi|258645684|ref|ZP_05733153.1| CRISPR-associated RAMP protein, ... 115 1e-23 gi|121533437|ref|ZP_01665265.1| CRISPR-associated RAMP protein, ... 103 3e-20 gi|323141260|ref|ZP_08076156.1| CRISPR-associated RAMP protein, ... 103 4e-20 gi|341822664|emb|CCC73588.1| CRISPR-associated RAMP protein [Meg... 100 4e-19 gi|334126728|ref|ZP_08500676.1| Csm4 family CRISPR-associated RA... 97.8 2e-18 gi|313894815|ref|ZP_07828375.1| CRISPR-associated RAMP protein, ... 93.2 4e-17 gi|292669139|ref|ZP_06602565.1| csm4 family CRISPR-associated ra... 92.4 8e-17 gi|312899097|ref|ZP_07758475.1| CRISPR-associated RAMP protein, ... 90.9 2e-16 gi|344997572|ref|YP_004799915.1| CRISPR-associated RAMP protein,... 88.2 1e-15 gi|312794662|ref|YP_004027585.1| crispr-associated ramp protein,... 87.8 2e-15 gi|345303032|ref|YP_004824934.1| CRISPR-associated RAMP protein,... 87.4 3e-15 >gi|15609957|ref|NP_217336.1| hypothetical protein Rv2820c [Mycobacterium tuberculosis H37Rv] gi|15842361|ref|NP_337398.1| hypothetical protein MT2887 [Mycobacterium tuberculosis CDC1551] gi|31793996|ref|NP_856489.1| hypothetical protein Mb2844c [Mycobacterium bovis AF2122/97] 63 more sequence titles Length=302 Score = 607 bits (1566), Expect = 5e-172, Method: Compositional matrix adjust. Identities = 302/302 (100%), Positives = 302/302 (100%), Gaps = 0/302 (0%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL Sbjct 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 Query 61 TDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQ 120 TDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQ Sbjct 61 TDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQ 120 Query 121 TKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISA 180 TKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISA Sbjct 121 TKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISA 180 Query 181 LGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRS 240 LGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRS Sbjct 181 LGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRS 240 Query 241 GFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPES 300 GFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPES Sbjct 241 GFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPES 300 Query 301 AA 302 AA Sbjct 301 AA 302 >gi|289751479|ref|ZP_06510857.1| hypothetical protein TBDG_02577 [Mycobacterium tuberculosis T92] gi|289692066|gb|EFD59495.1| hypothetical protein TBDG_02577 [Mycobacterium tuberculosis T92] Length=302 Score = 606 bits (1563), Expect = 1e-171, Method: Compositional matrix adjust. Identities = 301/302 (99%), Positives = 302/302 (100%), Gaps = 0/302 (0%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL Sbjct 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 Query 61 TDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQ 120 TDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQ Sbjct 61 TDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQ 120 Query 121 TKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISA 180 TKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLL+GISA Sbjct 121 TKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLRGISA 180 Query 181 LGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRS 240 LGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRS Sbjct 181 LGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRS 240 Query 241 GFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPES 300 GFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPES Sbjct 241 GFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPES 300 Query 301 AA 302 AA Sbjct 301 AA 302 >gi|340627816|ref|YP_004746268.1| hypothetical protein MCAN_28441 [Mycobacterium canettii CIPT 140010059] gi|340006006|emb|CCC45175.1| hypothetical protein MCAN_28441 [Mycobacterium canettii CIPT 140010059] Length=302 Score = 538 bits (1387), Expect = 3e-151, Method: Compositional matrix adjust. Identities = 281/302 (94%), Positives = 285/302 (95%), Gaps = 0/302 (0%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 MNSRLFRFD RTHFGDHGLESSTI CPADTLYSALCVEALRMGGQQLL ELVACSTLRL Sbjct 1 MNSRLFRFDVVRTHFGDHGLESSTIGCPADTLYSALCVEALRMGGQQLLDELVACSTLRL 60 Query 61 TDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQ 120 TDLLPYVGPDYLVPKPL SVRSD SS+QKKLAKKIGFLPAAQLGSFLDGTADL +LAARQ Sbjct 61 TDLLPYVGPDYLVPKPLKSVRSDSSSLQKKLAKKIGFLPAAQLGSFLDGTADLDDLAARQ 120 Query 121 TKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISA 180 TKIGVHAVSAKAAIHNGKKDADPYRVGYFRFE DAGLWLLATGSESELGLLTRLLKGISA Sbjct 121 TKIGVHAVSAKAAIHNGKKDADPYRVGYFRFEPDAGLWLLATGSESELGLLTRLLKGISA 180 Query 181 LGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRS 240 LGGERTSGFGAF TESE PAALTPT AASLMTLTTSLPTDDELE ALAGATYRLVKRS Sbjct 181 LGGERTSGFGAFIPTESEVPAALTPTTAAASLMTLTTSLPTDDELEQALAGATYRLVKRS 240 Query 241 GFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPES 300 GFVAS+TYA+ P RKRDIYK AAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPES Sbjct 241 GFVASATYAETPRRKRDIYKLAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPES 300 Query 301 AA 302 AA Sbjct 301 AA 302 >gi|323718577|gb|EGB27744.1| csm4 family CRISPR-associated ramp protein [Mycobacterium tuberculosis CDC1551A] Length=260 Score = 518 bits (1335), Expect = 4e-145, Method: Compositional matrix adjust. Identities = 260/260 (100%), Positives = 260/260 (100%), Gaps = 0/260 (0%) Query 43 MGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQ 102 MGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQ Sbjct 1 MGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQ 60 Query 103 LGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLAT 162 LGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLAT Sbjct 61 LGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLAT 120 Query 163 GSESELGLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTD 222 GSESELGLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTD Sbjct 121 GSESELGLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTD 180 Query 223 DELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGG 282 DELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGG Sbjct 181 DELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGG 240 Query 283 NHPVYSYARPLFLALPESAA 302 NHPVYSYARPLFLALPESAA Sbjct 241 NHPVYSYARPLFLALPESAA 260 >gi|289571007|ref|ZP_06451234.1| hypothetical protein TBJG_02426 [Mycobacterium tuberculosis T17] gi|289544761|gb|EFD48409.1| hypothetical protein TBJG_02426 [Mycobacterium tuberculosis T17] Length=237 Score = 460 bits (1184), Expect = 1e-127, Method: Compositional matrix adjust. Identities = 232/235 (99%), Positives = 232/235 (99%), Gaps = 0/235 (0%) Query 68 GPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHA 127 GP VPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHA Sbjct 3 GPITWVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHA 62 Query 128 VSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISALGGERTS 187 VSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISALGGERTS Sbjct 63 VSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGISALGGERTS 122 Query 188 GFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASST 247 GFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASST Sbjct 123 GFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASST 182 Query 248 YADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPESAA 302 YADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPESAA Sbjct 183 YADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLALPESAA 237 >gi|289746619|ref|ZP_06505997.1| predicted protein [Mycobacterium tuberculosis 02_1987] gi|289758938|ref|ZP_06518316.1| predicted protein [Mycobacterium tuberculosis T85] gi|294994090|ref|ZP_06799781.1| CRISPR-associated RAMP protein, Csm4 family [Mycobacterium tuberculosis 210] gi|289687147|gb|EFD54635.1| predicted protein [Mycobacterium tuberculosis 02_1987] gi|289714502|gb|EFD78514.1| predicted protein [Mycobacterium tuberculosis T85] gi|326904434|gb|EGE51367.1| hypothetical protein TBPG_02338 [Mycobacterium tuberculosis W-148] Length=118 Score = 236 bits (601), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 114/115 (99%), Positives = 114/115 (99%), Gaps = 0/115 (0%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL Sbjct 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 Query 61 TDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKE 115 TDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADL E Sbjct 61 TDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLNE 115 >gi|224543483|ref|ZP_03684022.1| hypothetical protein CATMIT_02692 [Catenibacterium mitsuokai DSM 15897] gi|224523610|gb|EEF92715.1| hypothetical protein CATMIT_02692 [Catenibacterium mitsuokai DSM 15897] Length=305 Score = 225 bits (574), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 123/306 (41%), Positives = 186/306 (61%), Gaps = 12/306 (3%) Query 1 MNSRLFRFDFDR-THFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLR 59 MN ++++ F + HFG+H LE S I ADTL+SALC+EAL++ + L + V + L Sbjct 1 MNYKIYKMIFTQGVHFGEHSLEKSEIIFQADTLFSALCIEALKIDKLETLLKSVKENHLV 60 Query 60 LTDLLPYVGPDYLVPKPLHSV----RSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKE 115 +D PY+ ++ VPKP+ + +S+ +++KK KK+ ++ + L +L G + + Sbjct 61 FSDAFPYMNQEFFVPKPMKKIEQVTQSEDMTIRKKF-KKLEYVQVSLLDQYLKGQYPIDK 119 Query 116 LAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLA-TGSESELGLLTRL 174 + K+GVHA+ A+I G ++A PYRVG +RFE GL+++ S+ L L +L Sbjct 120 -GSDIKKLGVHALKTSASI-RGNEEALPYRVGIYRFEKHNGLYIIVGYDSKETLHLFDKL 177 Query 175 LK--GISALGGERTSGFGAFNLTESEAPAALTPTVDAA-SLMTLTTSLPTDDELEAALAG 231 K +S +GG++ SG G F E P L ++ +MTL+ SLPTD E+E L Sbjct 178 FKMLSLSGIGGKKNSGLGHFRYNTVELPKELNNRLNTKGEVMTLSVSLPTDKEIEDILDD 237 Query 232 ATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYAR 291 + Y LVKRSGFV S TY+ RK+DIY F AGS F++ +QG I +VS GG+HPVY YA+ Sbjct 238 SRYLLVKRSGFVDSYTYSKEQRRKKDIYLFKAGSCFNKTYQGDIYNVSSGGSHPVYKYAK 297 Query 292 PLFLAL 297 PLF+ + Sbjct 298 PLFMGV 303 >gi|331004040|ref|ZP_08327522.1| csm4 family CRISPR-associated ramp protein [Lachnospiraceae oral taxon 107 str. F0167] gi|330411626|gb|EGG91034.1| csm4 family CRISPR-associated ramp protein [Lachnospiraceae oral taxon 107 str. F0167] Length=313 Score = 202 bits (514), Expect = 5e-50, Method: Compositional matrix adjust. Identities = 111/312 (36%), Positives = 179/312 (58%), Gaps = 15/312 (4%) Query 1 MNSRLFRFDFDR-THFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLR 59 MN ++ + DF HFG GLE ADT++SAL +EAL+ G L EL L+ Sbjct 1 MNYKILKLDFTTAVHFGSGGLEKGQNVLNADTIFSALFIEALKYGKSDRLLELCKNCKLK 60 Query 60 LTDLLPYVGPDYLVPKPLHSVRSD--GSSMQKKLAKKIGFLPAAQLGSFLDGTADLK-EL 116 +++ PY+G DY +PKP+ + +D G S+ KK KK+ ++P ++ F++G D+K E Sbjct 61 ISNAFPYIGCDYYLPKPIIRLNNDADGDSIIKKALKKLRYIPVSRFDDFINGKLDIKAEA 120 Query 117 AARQTKIGVHAVSAKAAIHNGKKDA--DPYRVGYFRFELDAGLWL-LATGSESELGLLTR 173 +G + K ++ +D + Y V F+++ D+GL+ + G++ + ++++ Sbjct 121 DLFGENLGESVLMEKVSMETASEDEVNNLYAVEIFKYKKDSGLYFFVGYGADEDFEMISK 180 Query 174 LLKGIS--ALGGERTSGFGAFNLTE----SEAPAALTPTVDAASLMTLTTSLPTDDELEA 227 L++ IS +GG+ +SG+G F L+ E + +M+L+ LP +DELE Sbjct 181 LMESISYTGIGGKVSSGYGKFKLSVDIPVKEIVKKFEDIDNYKDIMSLSLCLPNEDELEQ 240 Query 228 ALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVS--LGGNHP 285 +L GA+Y +VKRSGF+ASS YAD +K+D+Y AGSV+ F+G I DVS G HP Sbjct 241 SLEGASYTVVKRSGFIASSKYADTFRKKKDLYMIEAGSVYKNAFEGDIYDVSDKNNGTHP 300 Query 286 VYSYARPLFLAL 297 VY Y +P F+ + Sbjct 301 VYRYGKPFFMGV 312 >gi|253578037|ref|ZP_04855309.1| CRISPR-associated protein [Ruminococcus sp. 5_1_39B_FAA] gi|251850355|gb|EES78313.1| CRISPR-associated protein [Ruminococcus sp. 5_1_39BFAA] Length=306 Score = 196 bits (498), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 111/308 (37%), Positives = 180/308 (59%), Gaps = 13/308 (4%) Query 1 MNSRLFRFDF-DRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLR 59 MN L+ +F + HFG L+SS I+ ADTL+SAL EAL+M Q + V+ + Sbjct 1 MNYTLYCLEFINGVHFGRGNLDSSEITFHADTLFSALFQEALKMKKQDRFLKQVSDGKII 60 Query 60 LTDLLPYVGPDYLVPKPLHSVRSD-----GSSMQKKLAKKIGFLPAAQLGSFLDGTADLK 114 +D PY+G +Y +PKP+ +V+++ G S QKK K + ++P + L F++GT + Sbjct 61 FSDAFPYIGKNYYIPKPMIAVQTEDESKQGDSRQKKKFKNLNYIPVSTLADFVNGTFP-E 119 Query 115 ELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLA-TGSESELGLLTR 173 E +G++ + IH G ++ +P+RV + F GL++LA +ES+ LL Sbjct 120 EHMEDMKYLGLYDMKVSVGIH-GMEEPEPFRVNTWHFNTGTGLYVLAGYENESDRELLDE 178 Query 174 LLKGI--SALGGERTSGFGAFNLTESEAPAALTPTVDAASL--MTLTTSLPTDDELEAAL 229 L + + + +GG+++SG G F + P + + S + L+T+LP D+ELE + Sbjct 179 LFESLQYTGIGGKKSSGLGRFVYKVCKVPEDMMGYLKKKSEKNILLSTALPEDEELEQVM 238 Query 230 AGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSY 289 G++Y L+KRSGFV SS YA +RKRD+Y F++GS F+ F+G I++ GG HPV+ Y Sbjct 239 KGSSYLLIKRSGFVDSSEYALQQMRKRDLYVFSSGSCFAHTFRGRIIEERNGGKHPVFRY 298 Query 290 ARPLFLAL 297 A+ F+ + Sbjct 299 AKAFFMGV 306 >gi|289549402|ref|YP_003470306.1| CRISPR-associated RAMP protein, Csm4 family [Staphylococcus lugdunensis HKU09-01] gi|289178934|gb|ADC86179.1| CRISPR-associated RAMP protein, Csm4 family [Staphylococcus lugdunensis HKU09-01] gi|339893266|emb|CCB52452.1| CRISPR associated RAMP family protein [Staphylococcus lugdunensis N920143] Length=302 Score = 184 bits (466), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 111/315 (36%), Positives = 172/315 (55%), Gaps = 31/315 (9%) Query 1 MNSRLFRFDFDR-THFGDHGLESSTISCPADTLYSALCVEALRMGGQ--QLLGELVACST 57 M +++F+ F HFG L ++ ADTL+SAL E L +G Q L+ +L+ Sbjct 1 MITKIFKLSFKTPVHFGKKRLSDGEMTIKADTLFSALYTETLNLGKQTNWLMNDLI---- 56 Query 58 LRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGT---ADLK 114 ++D PY Y +PKPL + S+ K KK+ ++P ++ G D++ Sbjct 57 --ISDTFPYESELYYLPKPLIKIESNSEGNHKDF-KKLKYVPVYNYNDYIKGQLSEEDVR 113 Query 115 ELA--------ARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSES 166 +L + QTK VS KA + +D++PY VG F FE DAGL+ +A GSE Sbjct 114 DLNDIFRVGQFSLQTK-----VSLKAQEQSPNEDSEPYSVGTFSFEKDAGLYFIAKGSER 168 Query 167 ELGLLTRLLKGI--SALGGERTSGFGAFNLT--ESEAPAALTPTVDAASLMTLTTSLPTD 222 + L ++ + S +GG+R++G+G F T +E + L D + + L+TS+ Sbjct 169 TIQRLNEVMYALQFSGIGGKRSAGYGRFEYTCVSNENISNLL-NQDGDNFILLSTSMAKR 227 Query 223 DELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGG 282 +ELEA+L A Y L KR+GF+ S+TY+D ++K D Y F+ GSVF F+G I +V G Sbjct 228 EELEASLNKARYILSKRTGFIQSTTYSDRLVKKNDFYSFSVGSVFKTIFKGDIFNVGNQG 287 Query 283 NHPVYSYARPLFLAL 297 HPVY YA+PL++ + Sbjct 288 QHPVYRYAKPLWMEV 302 >gi|240143671|ref|ZP_04742272.1| CRISPR-associated RAMP protein, Csm4 family [Roseburia intestinalis L1-82] gi|257204348|gb|EEV02633.1| CRISPR-associated RAMP protein, Csm4 family [Roseburia intestinalis L1-82] Length=308 Score = 182 bits (461), Expect = 8e-44, Method: Compositional matrix adjust. Identities = 120/305 (40%), Positives = 173/305 (57%), Gaps = 11/305 (3%) Query 1 MNSRLFRFDFDR-THFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLR 59 M +++ +F HFG L S + AD ++SAL +EAL++ QQ L + V L Sbjct 5 MEYTIYQLEFKTGVHFGTGMLNESACTFKADQIFSALYIEALKLNLQQQLYDAVKKGNLL 64 Query 60 LTDLLPYVGPDYLVPKPLHSVR--SDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELA 117 ++D PY+G Y++PKP+ V + G S QKK KK+ F+P L FL+G DL Sbjct 65 ISDAFPYIGQQYMIPKPMIYVEPVNRGESKQKKAYKKMKFIPVECLIDFLNGKMDLSNDP 124 Query 118 ARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLAT-GSESELGLLTRLLK 176 G + AA+ G++ PYRVG F +E GL+++A SE+E L+ +LL Sbjct 125 MEH--YGHYFQQTMAAVRTGEETL-PYRVGTFYYEEGCGLYIIAAYQSENEKCLMEKLLT 181 Query 177 GIS--ALGGERTSGFGAFNLTESEAPAALTPTVDAAS--LMTLTTSLPTDDELEAALAGA 232 +S +GG+++ G G + E + P L + S M L+ +LP D+ELE A+ A Sbjct 182 ALSYTGIGGKKSGGLGKYRYNEGQIPEQLLECLQKKSDRYMLLSVALPADEELENAMENA 241 Query 233 TYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARP 292 +Y L KRSGFVASS YA+ +K+D+Y F AGS F F G I DVS GG HPVY YA+P Sbjct 242 SYLLEKRSGFVASSDYAEEWRKKKDLYVFTAGSCFVNCFAGDIYDVSEGGKHPVYRYAKP 301 Query 293 LFLAL 297 +F+ + Sbjct 302 IFMGV 306 >gi|291539923|emb|CBL13034.1| CRISPR-associated RAMP protein, Csm4 family [Roseburia intestinalis XB6B4] Length=304 Score = 179 bits (455), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 120/305 (40%), Positives = 172/305 (57%), Gaps = 11/305 (3%) Query 1 MNSRLFRFDFDR-THFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLR 59 M +++ +F HFG L S + AD ++SAL +EAL++ QQ L + V L Sbjct 1 MEYTIYQLEFKTGVHFGTGMLNESACTFKADQIFSALYIEALKLNLQQQLYDAVKKGNLL 60 Query 60 LTDLLPYVGPDYLVPKPLHSVR--SDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELA 117 ++D PY+G Y++PKP+ V + S QKK KK+ F+P L FL+G DL Sbjct 61 ISDAFPYIGQQYMIPKPMIYVEPVNRAESKQKKAYKKMKFIPVECLIDFLNGKMDLSNDP 120 Query 118 ARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGS-ESELGLLTRLLK 176 G + AA+ G++ PYRVG F +E GL+++A ++E L+ +LL Sbjct 121 MEH--YGHYFQQTMAAVRTGEETL-PYRVGTFYYEEGCGLYIIAAYQGKNEKCLMEKLLT 177 Query 177 GIS--ALGGERTSGFGAFNLTESEAPAALTPTVDAAS--LMTLTTSLPTDDELEAALAGA 232 +S +GG+++ G G F E + P L ++ S M L+ +LP DDELE AL A Sbjct 178 ALSYTGIGGKKSGGLGKFQYDEKQIPGKLLESLQKKSDRYMLLSVALPADDELENALENA 237 Query 233 TYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARP 292 +Y L KRSGFVASS YA+ +K+D+Y F AGS F F G I DVS GG HPVY YA+P Sbjct 238 SYLLEKRSGFVASSDYAEEWRKKKDLYVFTAGSCFVNCFAGDIYDVSEGGKHPVYRYAKP 297 Query 293 LFLAL 297 +F+ + Sbjct 298 IFMGV 302 >gi|229826461|ref|ZP_04452530.1| hypothetical protein GCWU000182_01834 [Abiotrophia defectiva ATCC 49176] gi|229789331|gb|EEP25445.1| hypothetical protein GCWU000182_01834 [Abiotrophia defectiva ATCC 49176] Length=309 Score = 178 bits (451), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 108/296 (37%), Positives = 163/296 (56%), Gaps = 12/296 (4%) Query 13 THFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVAC--STLRLTDLLPYVGPD 70 H G L + ADT++SALC EAL++G +L + AC ++LTD LP++ Sbjct 14 VHIGAGALTRGKYTLYADTVFSALCKEALKLGENKLSRLVEACRDDKIKLTDGLPFIEDR 73 Query 71 YLVPKPLHS--VRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLK-ELAARQTKIGVHA 127 Y VPKP+ + ++ KK AKK+ ++ ++ +L G+ D+K E IG H Sbjct 74 YYVPKPMLELDISTESDRTVKKAAKKLEYISIEKMDDYLSGSLDVKQENEYFSNNIGRHN 133 Query 128 VSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLL---KGISALGGE 184 + KA I G+ DA+PY V F + +GL++ EL + + S +GG+ Sbjct 134 LVGKAKIIIGE-DANPYVVDTFVYGEKSGLYVCVGVDNDELEAFVKEIFTSLSYSGVGGK 192 Query 185 RTSGFGAFNLTESEAPAALTPTVDAASL---MTLTTSLPTDDELEAALAGATYRLVKRSG 241 ++G+G F L A +D + M+L+ SLP+DDEL+ L+ A Y L+KRSG Sbjct 193 ISAGYGKFELEVVPATENFVKRLDNTAYKKYMSLSISLPSDDELKDVLSTADYLLIKRSG 252 Query 242 FVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLAL 297 FV+S TY++ +K+D Y AAG VF + F+G ILDVS GG H VY YA+P + + Sbjct 253 FVSSETYSETLRKKKDKYCMAAGFVFEKEFKGSILDVSNGGTHLVYRYAKPFIMGV 308 >gi|329736407|gb|EGG72676.1| CRISPR-associated RAMP protein, Csm4 family [Staphylococcus epidermidis VCU045] gi|341656676|gb|EGS80385.1| CRISPR-associated RAMP protein, Csm4 family [Staphylococcus epidermidis VCU037] Length=302 Score = 177 bits (449), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 107/315 (34%), Positives = 169/315 (54%), Gaps = 31/315 (9%) Query 1 MNSRLFRFDFDR-THFGDHGLESSTISCPADTLYSALCVEALRMGGQ--QLLGELVACST 57 M +++F+ F HFG L ++ ADTL+SAL +E L++G LL +L+ Sbjct 1 MATKVFKLSFKTPVHFGKKRLSDGEMTITADTLFSALFIETLQLGKDTDWLLNDLI---- 56 Query 58 LRLTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELA 117 ++D PY Y +PKPL + S K KK+ ++P +L+G EL+ Sbjct 57 --ISDTFPYENELYYLPKPLIKIDSKEEDNHKAF-KKLKYVPVHHYNQYLNG-----ELS 108 Query 118 ARQT-------KIGVHAVSAKAAI----HNGKKDADPYRVGYFRFELDAGLWLLATGSES 166 A IG ++ K ++ + D++PY VG F FE +AGL+ +A GSE Sbjct 109 AEDATDLNDIFNIGYFSLQTKVSLIAQETDSSADSEPYSVGTFTFEPEAGLYFIAKGSEE 168 Query 167 ELGLLTRLLKGI--SALGGERTSGFGAFN--LTESEAPAALTPTVDAASLMTLTTSLPTD 222 L L ++ + S LGG+R +G+G F + ++ + L S++ L+T++ Sbjct 169 TLDHLNNIMTALQYSGLGGKRNAGYGQFEYEIINNQQLSKLLNQNGKHSIL-LSTAMAKK 227 Query 223 DELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGG 282 +E+E+AL A Y L KRSGF+ S+ Y++M ++K D Y F++GSVF F G I +V G Sbjct 228 EEIESALKEARYILTKRSGFIQSTNYSEMLVKKSDFYSFSSGSVFKNIFDGDIFNVGHNG 287 Query 283 NHPVYSYARPLFLAL 297 HPVY YA+PL+L + Sbjct 288 KHPVYRYAKPLWLEV 302 >gi|57865881|ref|YP_190001.1| CRISPR-associated Csm4 family protein [Staphylococcus epidermidis RP62A] gi|57636539|gb|AAW53327.1| CRISPR-associated protein, TM1808 family [Staphylococcus epidermidis RP62A] Length=304 Score = 177 bits (448), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 107/313 (35%), Positives = 168/313 (54%), Gaps = 31/313 (9%) Query 3 SRLFRFDFDR-THFGDHGLESSTISCPADTLYSALCVEALRMGGQ--QLLGELVACSTLR 59 +++F+ F HFG L ++ ADTL+SAL +E L++G LL +L+ Sbjct 5 TKVFKLSFKTPVHFGKKRLSDGEMTITADTLFSALFIETLQLGKDTDWLLNDLI------ 58 Query 60 LTDLLPYVGPDYLVPKPLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAAR 119 ++D PY Y +PKPL + S K KK+ ++P +L+G EL+A Sbjct 59 ISDTFPYENELYYLPKPLIKIDSKEEDNHKAF-KKLKYVPVHHYNQYLNG-----ELSAE 112 Query 120 QT-------KIGVHAVSAKAAI----HNGKKDADPYRVGYFRFELDAGLWLLATGSESEL 168 IG ++ K ++ + D++PY VG F FE +AGL+ +A GSE L Sbjct 113 DATDLNDIFNIGYFSLQTKVSLIAQETDSSADSEPYSVGTFTFEPEAGLYFIAKGSEETL 172 Query 169 GLLTRLLKGI--SALGGERTSGFGAFN--LTESEAPAALTPTVDAASLMTLTTSLPTDDE 224 L ++ + S LGG+R +G+G F + ++ + L S++ L+T++ +E Sbjct 173 DHLNNIMTALQYSGLGGKRNAGYGQFEYEIINNQQLSKLLNQNGKHSIL-LSTAMAKKEE 231 Query 225 LEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNH 284 +E+AL A Y L KRSGFV S+ Y++M ++K D Y F++GSVF F G I +V G H Sbjct 232 IESALKEARYILTKRSGFVQSTNYSEMLVKKSDFYSFSSGSVFKNIFNGDIFNVGHNGKH 291 Query 285 PVYSYARPLFLAL 297 PVY YA+PL+L + Sbjct 292 PVYRYAKPLWLEV 304 >gi|291460038|ref|ZP_06599428.1| CRISPR-associated RAMP protein, Csm4 family [Oribacterium sp. oral taxon 078 str. F0262] gi|291417379|gb|EFE91098.1| CRISPR-associated RAMP protein, Csm4 family [Oribacterium sp. oral taxon 078 str. F0262] Length=305 Score = 177 bits (448), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 115/308 (38%), Positives = 162/308 (53%), Gaps = 16/308 (5%) Query 1 MNSRLFRFDFDRT-HFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLR 59 M ++R F + HFG L S ADTL+SA +EAL++G ++ L V L Sbjct 1 MKHLIYRLRFSTSVHFGRGMLSESAFCFSADTLFSAFYIEALKLGREEELYSAVKSGALC 60 Query 60 LTDLLPYVGPDYLVPKPLHSVRSD--GSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELA 117 +D P++ Y +PKP+ V S G S +KK KKI ++PA L F G EL Sbjct 61 FSDAFPFLRERYFLPKPMFYVESKAPGDSKEKKRFKKIQYIPAELLEDFFRG-----ELH 115 Query 118 ARQT---KIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLL-ATGSESELGLLTR 173 A ++G + +AA+ D PY VG F F GL+L+ A S E L+ Sbjct 116 AEHCDLGELGEESSQMRAAVSRSGDDTRPYCVGDFFFREGNGLYLIFALESNREEKLIEI 175 Query 174 LLKGIS--ALGGERTSGFGAFNLTESEAPAALTPTV--DAASLMTLTTSLPTDDELEAAL 229 L + +S +GG+R+SG G F+ E L + + M L ++LP + ELE+AL Sbjct 176 LFQSLSYSGIGGKRSSGKGRFSYERRELSEELQDAMMREGKRYMLLCSALPREVELESAL 235 Query 230 AGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSY 289 GA+Y L KRSGF+ S ++ +KRD+Y F +GS F FQG + V+ GG HPVY Y Sbjct 236 EGASYLLQKRSGFILSENFSPEQQKKRDLYTFRSGSCFRHRFQGVVYLVNEGGAHPVYRY 295 Query 290 ARPLFLAL 297 AR LFL + Sbjct 296 ARGLFLGV 303 >gi|315641550|ref|ZP_07896619.1| csm4 family CRISPR-associated ramp protein [Enterococcus italicus DSM 15952] gi|315482687|gb|EFU73214.1| csm4 family CRISPR-associated ramp protein [Enterococcus italicus DSM 15952] Length=307 Score = 171 bits (434), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 112/296 (38%), Positives = 165/296 (56%), Gaps = 22/296 (7%) Query 13 THFGDHGLESSTISCPADTLYSALCVEALRMGGQQL-LGELVACSTLRLTDLLPYVGPDY 71 HFG L S + ADTL+SAL +EAL+ QQL L L+ + L +TDL PY Y Sbjct 17 VHFGMKRLSDSNHTIAADTLFSALIIEALQ---QQLELSHLL--NNLVITDLFPYNKTSY 71 Query 72 LVPKPLHSVR-SDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELA--ARQTKIGVHAV 128 +PKPL + G K KK+ ++P +L G D E + A +G ++ Sbjct 72 FLPKPLIRIEGKKGDESGYKAFKKLTYIPVENYSEYLRGEIDSLEASKIAESLNLGKASL 131 Query 129 SAKAAI----HNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTRLLKGI--SALG 182 S K ++ HNG +++PY VG F F ++GL+ LA G+ +G L L+ + S +G Sbjct 132 STKVSLQAVDHNG--ESEPYSVGNFTFYPESGLYFLAKGNADTIGQLEILMHALQYSGIG 189 Query 183 GERTSGFGAFNLTESEA---PAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKR 239 G+R++G+G F T ++ + L+ T + A L L++++ +D+EL L A Y L KR Sbjct 190 GKRSAGYGQFRCTIEDSGKFDSLLSQTGNIAIL--LSSAMASDEELVDCLEDARYLLKKR 247 Query 240 SGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFL 295 +GFV S TYAD ++K+D Y F+AGS F + F G I DVS G H VY YA+ +L Sbjct 248 TGFVQSKTYADQLVKKKDFYAFSAGSTFYQKFNGKIFDVSDNGRHSVYRYAKAFWL 303 >gi|315925058|ref|ZP_07921275.1| CRISPR-associated Csm4 family protein [Pseudoramibacter alactolyticus ATCC 23263] gi|315621957|gb|EFV01921.1| CRISPR-associated Csm4 family protein [Pseudoramibacter alactolyticus ATCC 23263] Length=314 Score = 171 bits (433), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 123/315 (40%), Positives = 175/315 (56%), Gaps = 21/315 (6%) Query 1 MNSRLFRFDFDR-THFGDHGLESSTISCPADTLYSALCVEALRM--GGQQLLGELVACST 57 M + L +F+F HFGD LE+ + ADTL+SAL +EAL+ + L V Sbjct 1 MKTALIQFEFSSGVHFGDQRLENGRSTFGADTLFSALFIEALKRDEACAEALLNAVRDDR 60 Query 58 LRLTDLLPYVGPDYLVPKPLHSVRSD---GSSMQKKLAKKIGFLPAAQLGSFLDG----- 109 L +D +P++ Y +PKP + + G S KK KK+ ++ +FL G Sbjct 61 LNFSDGMPFMDERYYLPKPFIHIENKAEAGDSSVKKAYKKMAYVAVDCFDAFLKGEMPLA 120 Query 110 -TADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGS-ESE 167 T DL+ L K V + + +G+++ +PYRV +F F D GL++L + E E Sbjct 121 RTRDLEALGRFDMKTQVCLQNER---DSGQQEPEPYRVKHFYFNPDCGLYILVRAAGEEE 177 Query 168 LGLLTRLLKGIS--ALGGERTSGFGAFNLTESEAPAALTPTVDAA-SL-MTLTTSLPTDD 223 L+ LL +S +GG R+SG G F E+ P A+ + A SL MTL+ +LP D Sbjct 178 RQLMADLLTSLSFVGIGGRRSSGLGKFTWQEAPVPRAIVNRLAAGGSLHMTLSNALPADG 237 Query 224 ELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLG-G 282 L AALAGA+Y+LV+R GFVAS+ YA LRKRD+Y FAAGS F F G + DVS G G Sbjct 238 ALSAALAGASYKLVRRGGFVASAAYAREQLRKRDLYVFAAGSCFKTRFAGQVADVSTGAG 297 Query 283 NHPVYSYARPLFLAL 297 +HPVY A+P ++ + Sbjct 298 SHPVYRLAKPFWMEV 312 >gi|345284419|gb|AEN78272.1| CRISPR-associated protein, Csm4 family [Lactobacillus ruminis ATCC 27782] Length=306 Score = 170 bits (430), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 119/308 (39%), Positives = 161/308 (53%), Gaps = 24/308 (7%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +++R F R HFG L++S + A LYSALC+EA++ EL L Sbjct 1 MTFKIYRMSFQRAHFGKGYLDTSDMLFDASRLYSALCLEAIKNDCLNEFTELAESDGFFL 60 Query 61 TDLLPYVGPDYLVPKPL-----HSVRSDG---SSMQKKLAKKIGFLPAAQLGSFLDGTAD 112 +D P+VG Y PKP+ VR +G + + KL +I +P +++ +F+ G AD Sbjct 61 SDAFPHVGEPYF-PKPVCYPKKRMVRLEGLKEDNEKNKLTDRIVAVPMSEMSAFIRGEAD 119 Query 113 LKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLT 172 L Q ++ +K DPY VG F D +++LAT SE L+T Sbjct 120 YSVLFEDQEGFCRSSIVV-------RKGEDPYEVGVTTFSQD--VYVLATQSELLDELMT 170 Query 173 RLLKGISALGGERTSGFGAFNLTESEAPAALTP--TVDAASLMTLTTSLPTDDELEAALA 230 L S LGG+R+SG+G F+L E P L D M LTT+LP D EL A+ Sbjct 171 SL--QYSGLGGKRSSGYGRFDLAIEELPEGLEEMLNTDGNEQMLLTTALPQDAELHQAMT 228 Query 231 GATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGN-HPVYSY 289 GA Y L K SGF S T A +RK+D+YKF AGSVF F+G I DV G HPVY++ Sbjct 229 GARYDLKKSSGFAYSET-AGQLVRKQDLYKFRAGSVFVNKFKGQIADVRPDGYPHPVYNF 287 Query 290 ARPLFLAL 297 A+ LFL L Sbjct 288 AKGLFLDL 295 >gi|295105102|emb|CBL02646.1| CRISPR-associated RAMP protein, Csm4 family [Faecalibacterium prausnitzii SL3/3] Length=322 Score = 166 bits (420), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 115/327 (36%), Positives = 177/327 (55%), Gaps = 37/327 (11%) Query 1 MNSRLFRFDFDR-THFGDH----GLESSTISCPADTLYSALCVEALRMGGQQLLGELVAC 55 MN L + FD HFG G +SS ++ ADT++SALC AL + G+ L EL+ Sbjct 1 MNYFLLKLAFDTAVHFGGSDSAVGSQSSALTLRADTIFSALCHTALEVYGEPALEELLVS 60 Query 56 S---TLRLTDLLPYVGPDYLVPKPLHSVRSDG--SSMQKKLAKKIGFLPAAQL----GSF 106 + LR++D +P+ G + +PKP+ + S S++++K KK+ ++PA++ S Sbjct 61 ADADALRISDAMPWRGDTFYLPKPIAASTSPAELSTVERKAVKKLAWIPASKFDRYTASL 120 Query 107 LDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLL-ATGSE 165 GT L EL G KA++ +G DA PY VG +R GL++L A Sbjct 121 HTGTYPLDEL---DQSFGQAYEQTKASVTDGA-DAKPYFVGLYRLHAGCGLYVLCACEGN 176 Query 166 SELGLLTRL--LKGISALGGERTSGFGAFNLTESEAPAALTPTVDA-------------A 210 +L +L L L G+S +GG ++G+G F+L P L DA A Sbjct 177 DQLKMLKELFTLLGLSGIGGRTSAGYGRFHLDGE--PICLNTAEDASLRWMLQALERGTA 234 Query 211 SLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRP 270 + LT+SLPT +E++AAL GA ++L +R GF AS+ + + P++K+ Y AGSV Sbjct 235 PYLLLTSSLPTGEEMDAALEGAAFQLARRGGF-ASTEWVETPVKKQTQYFLTAGSVLQHT 293 Query 271 FQGGILDVSLGGNHPVYSYARPLFLAL 297 +QG + DV +G HPVY Y++PLF+ + Sbjct 294 YQGELCDVGIGVPHPVYRYSKPLFMGV 320 >gi|322387546|ref|ZP_08061155.1| csm4 family CRISPR-associated ramp protein [Streptococcus infantis ATCC 700779] gi|321141413|gb|EFX36909.1| csm4 family CRISPR-associated ramp protein [Streptococcus infantis ATCC 700779] Length=301 Score = 165 bits (418), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 115/313 (37%), Positives = 168/313 (54%), Gaps = 32/313 (10%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +++ +F HFG L+SS ++ AD L+SAL +EA +MG + L L Sbjct 1 MTYKMYIMNFQSAHFGAGTLDSSKMTFAADRLFSALAIEAKKMGKMEEFVSLAGQDEFVL 60 Query 61 TDLLPY-VGPDYLVPKPLHSVRSDGSSM---------QKKLAKKIGFLPAAQLGSFLDGT 110 TD PY GP +PKP+ + D + Q K+AKK+ F+P + S+++GT Sbjct 61 TDAFPYKSGP--FLPKPIGFPKFDQPDLTTDVKEVRRQAKMAKKLQFIPLDKFDSYVNGT 118 Query 111 ADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGL 170 L E A HAV+ + D Y+V RF + L+++AT S+ L Sbjct 119 --LFEDAE-------HAVTNIITKNQPHVDGHLYQVSTVRFADQSALYVIATESD----L 165 Query 171 LTRLLKGI--SALGGERTSGFGAFNLTESEAPAALT---PTVDAASLMTLTTSLPTDDEL 225 L +L+ + + +GG+R+SG+G F+LT ++ P AL V +MTL TSLP + EL Sbjct 166 LNQLMTSLQYTGIGGKRSSGYGRFDLTITDIPDALKNRLTKVHQGPVMTLATSLPVEKEL 225 Query 226 EAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVS-LGGNH 284 E A+ +Y L K SGF A ST + RK+D+YKFA+GS FS F G I+DV L H Sbjct 226 EYAMETGSYLLSKSSGF-AFSTETNENYRKQDLYKFASGSTFSETFTGHIVDVRPLDFPH 284 Query 285 PVYSYARPLFLAL 297 V +YA+PLF + Sbjct 285 EVLNYAKPLFFNM 297 >gi|270292489|ref|ZP_06198700.1| conserved hypothetical protein [Streptococcus sp. M143] gi|270278468|gb|EFA24314.1| conserved hypothetical protein [Streptococcus sp. M143] Length=301 Score = 161 bits (408), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 110/314 (36%), Positives = 165/314 (53%), Gaps = 28/314 (8%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +++ +F HFG L+SS ++ AD L+SAL +EA +MG + + L Sbjct 1 MTYKMYIMNFQSAHFGAGTLDSSKMTFAADRLFSALAIEAKKMGKMEEFVSIAGQDHFVL 60 Query 61 TDLLPYV-GPDYLVPKPLHSVRSDGSSM---------QKKLAKKIGFLPAAQLGSFLDGT 110 TD PY GP L+PKP+ + D + Q K+AKK+ F+P + S++ GT Sbjct 61 TDAFPYQSGP--LLPKPIGFPKFDQPDLTTDVKEVRRQAKMAKKLQFIPLDKFDSYVKGT 118 Query 111 ADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGL 170 E HAV+ + D + ++V RF D+ L+++A S+ L Sbjct 119 LFEDE---------EHAVTNIITKNQPHVDGNLFQVSTVRFRDDSSLYVIANESDLLNEL 169 Query 171 LTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAAS---LMTLTTSLPTDDELEA 227 +T L + +GG+R+SG+G F+LT + P +L + +MTLTTSLP + ELE Sbjct 170 MTSL--QYTGIGGKRSSGYGQFDLTILDLPDSLKNRLTKTHQEPVMTLTTSLPVEKELEY 227 Query 228 ALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVS-LGGNHPV 286 A+ +Y + K SGF A T + RK+D+YKFA+GS FS F G I+DV L H V Sbjct 228 AMETGSYLISKSSGF-AFGTETNENYRKQDLYKFASGSTFSETFTGHIVDVRPLDFPHEV 286 Query 287 YSYARPLFLALPES 300 +YA+PLF + E Sbjct 287 LNYAKPLFFKMEEE 300 >gi|322375483|ref|ZP_08049996.1| CRISPR-associated RAMP protein, Csm4 family [Streptococcus sp. C300] gi|321279746|gb|EFX56786.1| CRISPR-associated RAMP protein, Csm4 family [Streptococcus sp. C300] Length=301 Score = 161 bits (408), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 112/313 (36%), Positives = 163/313 (53%), Gaps = 32/313 (10%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +++ +F HFG L+SS ++ AD L+SAL +EA +MG + L L Sbjct 1 MTYKMYIMNFHTAHFGAGTLDSSKMTFAADRLFSALAIEAKKMGKMEEFVSLAGLDGFVL 60 Query 61 TDLLPYV-GPDYLVPKPLHSVRSDGSSM---------QKKLAKKIGFLPAAQLGSFLDGT 110 +D PY GP +PKP+ D + Q K+AKK+ F+P + S+++GT Sbjct 61 SDAFPYQSGP--FLPKPIGFPTFDQPDLTTDVKEVRRQAKMAKKLQFIPLDKFDSYVNGT 118 Query 111 ADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGL 170 K HAV+ + D Y+V R+ D+ L+++A SE L Sbjct 119 L---------FKDAEHAVTNIVTKNQPHLDGALYQVSTVRYRDDSSLYVIANESE----L 165 Query 171 LTRLLKGI--SALGGERTSGFGAFNLTESEAPAALT---PTVDAASLMTLTTSLPTDDEL 225 L L+ + + +GG+R+SG+G F+LT + P + V +MTLTTSLP + EL Sbjct 166 LNELMASLQYTGIGGKRSSGYGQFDLTILDLPDSFKNRLTKVHQGPVMTLTTSLPVEKEL 225 Query 226 EAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVS-LGGNH 284 E A+ +Y L K SGF A ST + RK+D+YKFA+GS FS F G I+DV L H Sbjct 226 EYAMETGSYLLSKSSGF-AFSTETNENYRKQDLYKFASGSTFSETFTGQIVDVRPLDFPH 284 Query 285 PVYSYARPLFLAL 297 V SYA+PLF + Sbjct 285 EVLSYAKPLFFKM 297 >gi|339278116|emb|CCC19864.1| hypothetical protein STH8232_1165 [Streptococcus thermophilus JIM 8232] Length=299 Score = 158 bits (399), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 113/313 (37%), Positives = 159/313 (51%), Gaps = 32/313 (10%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +L+ F HFG L+SS ++ AD ++SAL +EAL+MG L Sbjct 1 MTYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTL 60 Query 61 TDLLPY-VGPDYLVPKPL---------HSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGT 110 TD P+ GP +PKP+ SV Q KL+KK+ FL + +L+G Sbjct 61 TDAFPFQFGP--FLPKPIGYPKHDQIDQSVDVKEVRRQAKLSKKLQFLALENVDDYLNG- 117 Query 111 ADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGL 170 EL + HAV + KD + Y+V RF D L+++A S+ L Sbjct 118 ----ELFENED----HAVIDTVTKNQPHKDGNLYQVATTRFSNDTSLYVIANESD----L 165 Query 171 LTRLLKGI--SALGGERTSGFGAFNLTESEAPAALTPTV---DAASLMTLTTSLPTDDEL 225 L L+ + S LGG+R+SGFG F L P L+ + + +M+LTT+LP D +L Sbjct 166 LNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADL 225 Query 226 EAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVS-LGGNH 284 E A+ Y L K SGF A S + RK+D+YKFA+GS FS+ F+G I+DV L H Sbjct 226 EEAMEDGHYLLTKSSGF-AFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPH 284 Query 285 PVYSYARPLFLAL 297 V +YA+PLF L Sbjct 285 AVLNYAKPLFFKL 297 >gi|312278324|gb|ADQ62981.1| CRISPR-associated protein, Csm4 family [Streptococcus thermophilus ND03] Length=299 Score = 158 bits (399), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 113/313 (37%), Positives = 159/313 (51%), Gaps = 32/313 (10%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +L+ F HFG L+SS ++ AD ++SAL +EAL+MG L Sbjct 1 MTYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLEALKMGKLDAFLAEANQDKFTL 60 Query 61 TDLLPY-VGPDYLVPKPL---------HSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGT 110 TD P+ GP +PKP+ SV Q KL+KK+ FL + +L+G Sbjct 61 TDAFPFQFGP--FLPKPIGYPKHDQIDQSVDVKEVRRQAKLSKKLQFLALENVDDYLNG- 117 Query 111 ADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGL 170 EL + HAV + KD + Y+V RF D L+++A S+ L Sbjct 118 ----ELFENEE----HAVIDTVTKNQPHKDDNLYQVATTRFSNDTSLYVIANESD----L 165 Query 171 LTRLLKGI--SALGGERTSGFGAFNLTESEAPAALTPTV---DAASLMTLTTSLPTDDEL 225 L L+ + S LGG+R+SGFG F L P L+ + + +M+LTT+LP D +L Sbjct 166 LNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADL 225 Query 226 EAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVS-LGGNH 284 E A+ Y L K SGF A S + RK+D+YKFA+GS FS+ F+G I+DV L H Sbjct 226 EEAMEDGHYLLTKSSGF-AFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPH 284 Query 285 PVYSYARPLFLAL 297 V +YA+PLF L Sbjct 285 AVLNYAKPLFFKL 297 >gi|55820998|ref|YP_139440.1| hypothetical protein stu0963 [Streptococcus thermophilus LMG 18311] gi|116627769|ref|YP_820388.1| hypothetical protein STER_0976 [Streptococcus thermophilus LMD-9] gi|55736983|gb|AAV60625.1| conserved hypothetical protein [Streptococcus thermophilus LMG 18311] gi|116101046|gb|ABJ66192.1| CRISPR-associated protein, Csm4 family [Streptococcus thermophilus LMD-9] Length=299 Score = 157 bits (397), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 112/313 (36%), Positives = 159/313 (51%), Gaps = 32/313 (10%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +L+ F HFG L+SS ++ AD ++SAL +E+L+MG L Sbjct 1 MTYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLESLKMGKLDAFLAEANQDKFTL 60 Query 61 TDLLPY-VGPDYLVPKPL---------HSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGT 110 TD P+ GP +PKP+ SV Q KL+KK+ FL + +L+G Sbjct 61 TDAFPFQFGP--FLPKPIGYPKHDQIDQSVDVKEVRRQAKLSKKLQFLALENVDDYLNG- 117 Query 111 ADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGL 170 EL + HAV + KD + Y+V RF D L+++A S+ L Sbjct 118 ----ELFENEE----HAVIDTVTKNQPHKDGNLYQVATTRFSNDTSLYVIANESD----L 165 Query 171 LTRLLKGI--SALGGERTSGFGAFNLTESEAPAALTPTV---DAASLMTLTTSLPTDDEL 225 L L+ + S LGG+R+SGFG F L P L+ + + +M+LTT+LP D +L Sbjct 166 LNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADL 225 Query 226 EAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVS-LGGNH 284 E A+ Y L K SGF A S + RK+D+YKFA+GS FS+ F+G I+DV L H Sbjct 226 EEAMEDGHYLLTKSSGF-AFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPH 284 Query 285 PVYSYARPLFLAL 297 V +YA+PLF L Sbjct 285 AVLNYAKPLFFKL 297 >gi|55822917|ref|YP_141358.1| hypothetical protein str0963 [Streptococcus thermophilus CNRZ1066] gi|55738902|gb|AAV62543.1| conserved hypothetical protein [Streptococcus thermophilus CNRZ1066] Length=299 Score = 156 bits (395), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 111/313 (36%), Positives = 159/313 (51%), Gaps = 32/313 (10%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +L+ F HFG L+SS ++ AD ++SAL +E+L+MG L Sbjct 1 MTYKLYIMTFQNAHFGSGTLDSSKLTFSADRIFSALVLESLKMGKLDAFLAEANQDKFTL 60 Query 61 TDLLPY-VGPDYLVPKPL---------HSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGT 110 TD P+ GP +PKP+ SV Q KL+KK+ FL + +++G Sbjct 61 TDAFPFQFGP--FLPKPIGYPKHDQIDQSVDVKEVRRQAKLSKKLQFLALENVDDYING- 117 Query 111 ADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGL 170 EL + HAV + KD + Y+V RF D L+++A S+ L Sbjct 118 ----ELFENEE----HAVIDTVTKNQPHKDGNLYQVATTRFSNDTSLYVIANESD----L 165 Query 171 LTRLLKGI--SALGGERTSGFGAFNLTESEAPAALTPTV---DAASLMTLTTSLPTDDEL 225 L L+ + S LGG+R+SGFG F L P L+ + + +M+LTT+LP D +L Sbjct 166 LNELMSSLQYSGLGGKRSSGFGRFELDIQNIPLELSDRLTKNHSDKVMSLTTALPVDADL 225 Query 226 EAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVS-LGGNH 284 E A+ Y L K SGF A S + RK+D+YKFA+GS FS+ F+G I+DV L H Sbjct 226 EEAMEDGHYLLTKSSGF-AFSHATNENYRKQDLYKFASGSTFSKTFEGQIVDVRPLDFPH 284 Query 285 PVYSYARPLFLAL 297 V +YA+PLF L Sbjct 285 AVLNYAKPLFFKL 297 >gi|334308472|gb|EGL99458.1| CRISPR-associated RAMP protein, Csm4 family [Lactobacillus salivarius NIAS840] Length=305 Score = 151 bits (382), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 97/313 (31%), Positives = 160/313 (52%), Gaps = 29/313 (9%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M + ++ DF HFG+ L S S A LYS+L +E+L++ + L + L Sbjct 1 MEVQAYKLDFQTVHFGNGNLNESIGSFNASRLYSSLFLESLKLNVDKEFLNLSKSANFFL 60 Query 61 TDLLPYVGPDYLVPK-------PLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADL 113 +D P ++ +PK PL+S + + + K +KK+ ++ + +++G D+ Sbjct 61 SDSFPLKDGEFYLPKPIGYPKIPLNSESTRETRRKAKRSKKLRYIKYTDMEDYVEGNCDV 120 Query 114 KELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTR 173 +L + V K I DPY VG F+ L++L + LL Sbjct 121 DKLDGTDSFFSKSTVVTKKGI-------DPYEVGITNFK--TSLYILTIKHK----LLDM 167 Query 174 LLKGI--SALGGERTSGFGAFNLTESEAPAALTPTV-----DAASLMTLTTSLPTDDELE 226 L+ + S +GG+R+SG+G F + + + P + + + MTL+TS+P +DEL+ Sbjct 168 LMNSLQYSGIGGKRSSGYGRFTVEKLDIPDEFSKNIVVNDSEYGVYMTLSTSIPNNDELD 227 Query 227 AALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGG-NHP 285 + L A Y L K SGF SST ++ LRK+D+YKFA G+ ++ + G I DV G +HP Sbjct 228 SVLPTAEYLLEKSSGFAYSSTSRNL-LRKQDLYKFAVGTTLTKTYNGNIFDVRPDGFSHP 286 Query 286 VYSYARPLFLALP 298 V++YA+ LF LP Sbjct 287 VWNYAKGLFYKLP 299 >gi|227890794|ref|ZP_04008599.1| CRISPR-associated Csm4 family protein [Lactobacillus salivarius ATCC 11741] gi|227867203|gb|EEJ74624.1| CRISPR-associated Csm4 family protein [Lactobacillus salivarius ATCC 11741] Length=305 Score = 142 bits (358), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 99/313 (32%), Positives = 160/313 (52%), Gaps = 29/313 (9%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M + ++ DF HFG+ L S S A LYSAL +E+L++ + +L L Sbjct 1 MEVQAYKLDFQTVHFGNGNLNESIGSFNASRLYSALFLESLKLNVDKEFLDLSKSDNFLL 60 Query 61 TDLLPYVGPDYLVPK-------PLHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADL 113 +D P ++ +PK PL+S + + + K +KK+ ++ + +++G D+ Sbjct 61 SDSFPLKDGEFYLPKPIGYPKMPLNSESTKETRRKTKKSKKLRYIKYTDIEDYVEGNCDV 120 Query 114 KELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLLTR 173 ++L G+ + +K + KK DPY VG F+ L++L E LL Sbjct 121 EKLD------GIDSFFSKNTVVT-KKGIDPYEVGITNFK--TSLYILTIKHE----LLDM 167 Query 174 LLKGI--SALGGERTSGFGAFNLTESEAPAALTPTV-----DAASLMTLTTSLPTDDELE 226 L+ + S +GG+R+SG+G F + + + P + + + MTL TS+P +DEL+ Sbjct 168 LMNSLQYSGIGGKRSSGYGRFTVEKLDIPNEFSKNIVINDSEYGVYMTLNTSIPNNDELD 227 Query 227 AALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGG-NHP 285 L A Y L K SGF A ST + LRK+D+YKF G+ ++ + G I DV G HP Sbjct 228 VVLPTAEYLLEKSSGF-AYSTASKSLLRKQDLYKFVVGTTLTKTYSGNIFDVRPDGFPHP 286 Query 286 VYSYARPLFLALP 298 V++YA+ LF LP Sbjct 287 VWNYAKGLFYKLP 299 >gi|125718068|ref|YP_001035201.1| hypothetical protein SSA_1248 [Streptococcus sanguinis SK36] gi|125497985|gb|ABN44651.1| Conserved hypothetical protein [Streptococcus sanguinis SK36] Length=302 Score = 140 bits (354), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 106/317 (34%), Positives = 159/317 (51%), Gaps = 33/317 (10%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +L++ DF HFG+ L+ S ++ A LYSAL +EA++ G L L Sbjct 1 MAYQLYKLDFKSAHFGEGHLDDSVMTFTAARLYSALVLEAIKAGVLDEFENLSRQDEFVL 60 Query 61 TDLLPYVGPDYLVPKP-----LHSVRSDGSSMQK----KLAKKIGFLPAAQLGSFLDGTA 111 TD PY+G YL PKP L V + +++ K AKK+ F+ FL G + Sbjct 61 TDAFPYMGAPYL-PKPIGYPLLDKVNRNEDIIKQREEAKKAKKLAFIKLGDFDCFLSGNS 119 Query 112 DLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLL 171 + E + +++ K + +D + Y+V F+ + L+ +A S+ LL Sbjct 120 IVGE------SLATKSINTK---NQPFQDGNLYQVASVHFD-KSSLYFIANQSD----LL 165 Query 172 TRLLKGI--SALGGERTSGFGAFNLTES-EAPAALTPTVDA---ASLMTLTTSLPTDDEL 225 RLL+ + S +GG+R+SG+G F L ++ + P + +M LTTSLP D EL Sbjct 166 DRLLESLQFSGIGGKRSSGYGGFTLDKTVQQPLDFFKRLTVKYTGKVMALTTSLPVDSEL 225 Query 226 EAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGN-- 283 + A+ Y L K SGF A S + RK+++Y F AGS FS+ + G I DV Sbjct 226 KVAMNEGRYLLKKSSGF-AFSEETESNYRKQNLYTFKAGSTFSKTYNGQICDVKPSDEFP 284 Query 284 HPVYSYARPLFLALPES 300 H V+ YA+PLF L ES Sbjct 285 HSVWHYAKPLFYILEES 301 >gi|114567268|ref|YP_754422.1| hypothetical protein Swol_1753 [Syntrophomonas wolfei subsp. wolfei str. Goettingen] gi|114338203|gb|ABI69051.1| CRISPR-associated protein, Csm4 family [Syntrophomonas wolfei subsp. wolfei str. Goettingen] Length=315 Score = 140 bits (353), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 99/317 (32%), Positives = 157/317 (50%), Gaps = 24/317 (7%) Query 1 MNSRLFRFDFDRT-HFG-DHG---LESSTISCPADTLYSALCVEALRMGGQQLLGELVAC 55 M L+R +F H G D G L+ + ADTL++ALC EA+R G L + A Sbjct 1 MEHFLYRLNFSTALHIGKDAGGPSLDDGQMIIHADTLFAALCCEAVRGGRITQLVKYFAD 60 Query 56 STLRLTDLLPYVGPDYLVPKPL----HSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTA 111 L ++D LPY G + +P+P+ + R+ S++ K L K ++P + G +L Sbjct 61 GILSISDALPYAGDEIFLPRPVLFTENRKRAGDSALAKALKNK-DYIPLSFFGDYLKSMQ 119 Query 112 DLK---ELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESEL 168 L E ++ G + AI G PY V +RF GL+++ + E Sbjct 120 QLDFNLESLKSESDFGYLTTLTRVAI-KGNSPPLPYHVAAWRFADGCGLYIIVRSEQEEA 178 Query 169 -----GLLTRLLKGISALGGERTSGFGAFNLTESEAPAALTPTVD---AASLMTLTTSLP 220 LL L G+S +GG+++SG+G F + P L ++ A M + T+LP Sbjct 179 RTMFASLLAEL--GLSGIGGKQSSGWGKFEVKPGPVPDELLRLLEDKQAEYQMLMGTALP 236 Query 221 TDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSL 280 D+EL+ L Y+L++R GF+ S +YA ++K+ IY A+GS F+G +LD+S Sbjct 237 VDNELDTVLLNGWYKLLRRGGFIRSESYAARQMKKKTIYMLASGSCLRSRFKGAMLDLSD 296 Query 281 GGNHPVYSYARPLFLAL 297 G HPV+ LF+ + Sbjct 297 NGAHPVWRCGNTLFVGV 313 >gi|325687527|gb|EGD29548.1| hypothetical protein HMPREF9381_1061 [Streptococcus sanguinis SK72] Length=302 Score = 138 bits (347), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 105/317 (34%), Positives = 159/317 (51%), Gaps = 33/317 (10%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +L++ DF HFG+ L+ S ++ A LYSAL +EA++ G L L Sbjct 1 MAYQLYKLDFKSAHFGEGHLDDSVMTFTAARLYSALVLEAIKAGVLDEFENLSRQDEFVL 60 Query 61 TDLLPYVGPDYLVPKP-----LHSVRSDGSSMQK----KLAKKIGFLPAAQLGSFLDGTA 111 TD PY+ YL PKP L V + +++ K AKK+ F+ FL G + Sbjct 61 TDAFPYMEVPYL-PKPIGYPLLDKVNRNEDIIKQREEAKKAKKLAFIKLGDFDCFLSGNS 119 Query 112 DLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLL 171 + E + +++ K + +D + Y+V F+ + L+ +A S+ LL Sbjct 120 IVGE------SLATKSINTK---NQPFQDGNLYQVASVHFD-KSSLYFIANQSD----LL 165 Query 172 TRLLKGI--SALGGERTSGFGAFNLTES-EAPAALTPTVDA---ASLMTLTTSLPTDDEL 225 RLL+ + S +GG+R+SG+G F L ++ + P + +M LTTSLP D EL Sbjct 166 DRLLESLQFSGIGGKRSSGYGGFTLDKTVQQPLDFFKRLTVKYTGKVMALTTSLPVDSEL 225 Query 226 EAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGN-- 283 + A+ Y L K SGF A S + RK+++Y F AGS FS+ + G I DV + Sbjct 226 KVAMNEGRYLLKKSSGF-AFSEETESNYRKQNLYTFKAGSTFSKTYNGQICDVKPSDDFP 284 Query 284 HPVYSYARPLFLALPES 300 H V+ YA+PLF L ES Sbjct 285 HSVWHYAKPLFYILEES 301 >gi|327469967|gb|EGF15431.1| hypothetical protein HMPREF9386_0578 [Streptococcus sanguinis SK330] Length=302 Score = 138 bits (347), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 105/317 (34%), Positives = 159/317 (51%), Gaps = 33/317 (10%) Query 1 MNSRLFRFDFDRTHFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRL 60 M +L++ DF HFG+ L+ S ++ A LYSAL +EA++ G L L Sbjct 1 MAYQLYKLDFKSAHFGEGHLDDSVMTFTAARLYSALVLEAIKAGVLDEFENLSLQDEFVL 60 Query 61 TDLLPYVGPDYLVPKP-----LHSVRSDGSSMQK----KLAKKIGFLPAAQLGSFLDGTA 111 TD PY+ YL PKP L V + +++ K AKK+ F+ FL G + Sbjct 61 TDAFPYMEAPYL-PKPIGYPLLDKVNRNEDIIKQREEAKKAKKLAFIKLGDFDYFLSGNS 119 Query 112 DLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESELGLL 171 + E + +++ K + ++ + Y+V F+ ++ L+ +A S+ LL Sbjct 120 IVGE------SLATKSINTK---NQPFQEGNLYQVASVHFDKNS-LYFIANQSD----LL 165 Query 172 TRLLKGI--SALGGERTSGFGAFNLTES-EAPAALTPTVDA---ASLMTLTTSLPTDDEL 225 RLL+ + S +GG+R+SG+G F L ++ + P + +M LTTSLP D EL Sbjct 166 DRLLESLQFSGIGGKRSSGYGGFTLDKTVQQPLDFFKRLTVKYTGKVMALTTSLPVDSEL 225 Query 226 EAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGN-- 283 + A+ Y L K SGF A S + RK+++Y F AGS FS + G I DV Sbjct 226 KVAMNEGRYLLKKSSGF-AFSEETESNYRKQNLYTFKAGSTFSETYNGQICDVKPSDEFP 284 Query 284 HPVYSYARPLFLALPES 300 HPV+ YA+PLF L ES Sbjct 285 HPVWHYAKPLFYMLEES 301 >gi|296133518|ref|YP_003640765.1| CRISPR-associated RAMP protein, Csm4 family [Thermincola sp. JR] gi|296032096|gb|ADG82864.1| CRISPR-associated RAMP protein, Csm4 family [Thermincola potens JR] Length=326 Score = 137 bits (346), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 99/302 (33%), Positives = 157/302 (52%), Gaps = 27/302 (8%) Query 20 LESSTISCPADTLYSALCVEALRMGGQQLLGELVAC---STLRLTDLLPYVGPDYLVPKP 76 L ++C ADTL+SALC E + + GQ+ EL+A + + L+D+ P+ G + +PKP Sbjct 26 LAQGKMACTADTLFSALCQEWIAVFGQKGFDELIAAVQGNQIFLSDMFPWCGLELYLPKP 85 Query 77 LH--SVR--SDGSSMQ-KKLAKKIGFLPAAQLG---SFLDGTADLKELAARQTKIGVHAV 128 SVR +D ++ +K KK+ ++P ++ FL DL L + G + Sbjct 86 AMPPSVRRNTDVEGLKDRKALKKLVYIPVSRFADYIKFLHNGGDLPWLE-EIVEPGYEQL 144 Query 129 SAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSE---SELGLLTRLLKGISALGGER 185 +A I ++D PY V +RF+ ++GL+ + +E ++ L G++ +GG+R Sbjct 145 LYRANIAR-EQDTVPYPVMVYRFKENSGLYFILRSTEYWRERFDIVVESL-GLTGIGGKR 202 Query 186 TSGFGAFNLTESEAPAALTPT---------VDAASLMTLTTSLPTDDELE-AALAGATYR 235 +SG G F L E L + DA M L+ P +EL A A + Y Sbjct 203 SSGLGKFELAEESFETGLYDSDIMLEKMLLEDANLYMLLSVLSPGQEELGIAKQANSYYN 262 Query 236 LVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFL 295 LVKR+G+VAS YAD L+K+ + F AGS F +G +LDVS G HPVY Y + +++ Sbjct 263 LVKRTGYVASPDYADTWLKKKPVVMFGAGSCFPEKIRGRVLDVSDCGGHPVYRYGKGMYV 322 Query 296 AL 297 + Sbjct 323 GV 324 >gi|225018978|ref|ZP_03708170.1| hypothetical protein CLOSTMETH_02929 [Clostridium methylpentosum DSM 5476] gi|224948258|gb|EEG29467.1| hypothetical protein CLOSTMETH_02929 [Clostridium methylpentosum DSM 5476] Length=319 Score = 134 bits (337), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 99/309 (33%), Positives = 151/309 (49%), Gaps = 30/309 (9%) Query 13 THFG-DHG---LESSTISCPADTLYSALCVEALRMGGQQLLGELV---ACSTLRLTDLLP 65 H G DHG LESS + +D+ +SALCVEA R GG +++ LV S + L+DLLP Sbjct 15 VHIGPDHGQSPLESSMTTMHSDSFFSALCVEAARYGGSEMVENLVDDARQSRMVLSDLLP 74 Query 66 YVGPDYLVPKP---LHSVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTK 122 G + +PKP R + S +K KK+ F+P + + + K ++ K Sbjct 75 CRGEELFLPKPNLPFVQARVEADSENRKEFKKMRFVPISMWTDYCKFCFEEKPFPLKKCK 134 Query 123 IGVHAVS-----AKAAIHNGKKDADPYRVGYFRFELDAGLW-LLATGSESELGLLTRLLK 176 + S + A+ G +D +PY + F D+ L+ +L S +LL Sbjct 135 EAMQGFSYPDQRQRVAV-EGSEDPEPYFLQATSFPPDSSLYCILGFDSGQTRSKWEQLLN 193 Query 177 GI--SALGGERTSGFGAFN------LTESEAPAALTPTVDAASLMTLTTSLPTDDELEAA 228 + S +GG+R+SG+G F L + A DA +TL TSLPTD+EL + Sbjct 194 SLAWSGIGGKRSSGWGKFEVSSPDPLENHQVLHAGLSAKDAPMWITLNTSLPTDEELRSI 253 Query 229 LAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYS 288 ++Y L +R GFV Y +KR +Y F+AGS F+G +LD++ G VY Sbjct 254 AQQSSYLLCRRGGFVDGEAY-----KKRTVYAFSAGSCVHTRFEGDVLDLAPKGRRAVYR 308 Query 289 YARPLFLAL 297 +P+ L + Sbjct 309 MLKPILLGV 317 >gi|237741577|ref|ZP_04572058.1| CRISPR-associated protein [Fusobacterium sp. 4_1_13] gi|229429225|gb|EEO39437.1| CRISPR-associated protein [Fusobacterium sp. 4_1_13] Length=336 Score = 132 bits (333), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 84/317 (27%), Positives = 151/317 (48%), Gaps = 33/317 (10%) Query 13 THFGDHGLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPY-----V 67 T FG + LE + IS +DT YSAL E +++ L ++ L+DLLP+ + Sbjct 18 TAFG-NTLEETMISVYSDTFYSALFNEYMKIYNNDELYKISESGDFLLSDLLPFKEKEDM 76 Query 68 GPDYLVPKPLHSV------RSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQT 121 D+ +PKP ++ + D + +K K F+PA +LG + + K Sbjct 77 STDFYLPKPFINIERKEIKKDDEEKIDRKKVKATNFIPADKLGEYFSFLKNGKNFPEIDD 136 Query 122 KIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLAT--GSESELGLLTRLLKGIS 179 G + K + +D Y + F+F +GL+ + E + +L+ +S Sbjct 137 NFGKKQLYTKNKVSLENEDTKLYNIEIFKFNEKSGLYFIVKLPKDEKWQRIFENILESLS 196 Query 180 --ALGGERTSGFGAFNLTE--------------SEAPAALTPTV--DAASLMTLTTSLPT 221 +GG++ SGFG F + E SE+ A + + + + +++ P Sbjct 197 LTGIGGKKNSGFGQFTIKEDAMNFDGLDFEKFESESDAYINKALYSNEEKFLIISSYSPR 256 Query 222 DDELEAALAGATY-RLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSL 280 +E+E G Y +L+KRSGFV SS+Y++ +++ +Y ++GSV + +G ILD++L Sbjct 257 IEEIEKLKDGNNYYQLIKRSGFVNSSSYSEQAEKRKQVYMLSSGSVLNFKPEGKILDLNL 316 Query 281 GGNHPVYSYARPLFLAL 297 G H +Y +P+ L + Sbjct 317 HGKHSIYRMGKPIVLGV 333 >gi|294782690|ref|ZP_06748016.1| CRISPR-associated RAMP protein, Csm4 family [Fusobacterium sp. 1_1_41FAA] gi|294481331|gb|EFG29106.1| CRISPR-associated RAMP protein, Csm4 family [Fusobacterium sp. 1_1_41FAA] Length=334 Score = 126 bits (316), Expect = 5e-27, Method: Compositional matrix adjust. Identities = 82/311 (27%), Positives = 148/311 (48%), Gaps = 35/311 (11%) Query 20 LESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPY-----VGPDYLVP 74 LE + +S +DT YSA+ E +++ L ++ ++DLLP+ + D+ +P Sbjct 24 LEETMMSVYSDTFYSAVFNEYMKIYNDDELYKISEAGEFLVSDLLPFKEKEDMSTDFYLP 83 Query 75 KPLHSV------RSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHAV 128 KP SV +++ + +K K F+PA +LG +L K G + Sbjct 84 KPFISVQRQEIEKNEEEVVDRKKVKATNFIPADKLGEYLTFLKTGKNFPEIDDDFGKKEL 143 Query 129 SAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESE------LGLLTRLLKGISALG 182 K + +D Y + F+F +GL+ + E G+L L ++ +G Sbjct 144 YTKNKVSLQNEDTKLYNIEVFKFNEKSGLYFIVKIPEDNRWQEIFQGVLDSL--ALTGIG 201 Query 183 GERTSGFG-------------AFNLTESEAPAALTPTV--DAASLMTLTTSLPTDDELEA 227 G+R SGFG F+ ESE+ A + + D + ++L++ P +E++ Sbjct 202 GKRNSGFGQFRREEPMFFDGETFDAIESESDAYINRGLYSDEKNFLSLSSYSPKKEEIDK 261 Query 228 ALAGATY-RLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPV 286 Y +L+KRSGFV SS Y++ +++ +Y ++GSV + +G ILD++L G H + Sbjct 262 IKESENYYQLIKRSGFVNSSLYSEQAEKRKQVYMLSSGSVLTFKPEGKILDLNLHGKHSI 321 Query 287 YSYARPLFLAL 297 Y +P+ L + Sbjct 322 YRMGKPIVLGV 332 >gi|340752432|ref|ZP_08689231.1| csm4 family CRISPR-associated ramp protein [Fusobacterium sp. 2_1_31] gi|229422231|gb|EEO37278.1| csm4 family CRISPR-associated ramp protein [Fusobacterium sp. 2_1_31] Length=334 Score = 121 bits (304), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 83/309 (27%), Positives = 147/309 (48%), Gaps = 31/309 (10%) Query 20 LESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPY-----VGPDYLVP 74 LE + +S +DT YSA+ E +++ L ++ ++DLLP+ + D+ +P Sbjct 24 LEETMMSVYSDTFYSAIFNEYMKIYNDDELYKISEAGEFLVSDLLPFKEKEDMSTDFYLP 83 Query 75 KPLHSV------RSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTKIGVHAV 128 KP SV +++ + +K K F+PA +LG +L K G + Sbjct 84 KPFISVQRQEMGKNEEEVVDRKKVKATNFIPADKLGEYLTFLKTGKNFPEIDDDFGKKEL 143 Query 129 SAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGSESE--LGLLTRLLKGIS--ALGGE 184 K + +D Y + F+F +GL+ + E + +L+ +S +GG+ Sbjct 144 YTKNKVSLQNEDTKLYNIEVFKFNEKSGLYFIVKLPEDNEWQEIFENILESLSLTGIGGK 203 Query 185 RTSGFGAF-------------NLTESEAPAALTPTV--DAASLMTLTTSLPTDDELEAAL 229 R SGFG F + ESE+ A + + D ++L++ P +E+E Sbjct 204 RNSGFGQFISEDPMFFDGEDFDAIESESDAYINKALYSDEEKYLSLSSYSPKIEEIEKIK 263 Query 230 AGATY-RLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYS 288 Y +L+KRSGFV SS Y++ +++ +Y ++GSV S +G ILD++L G H +Y Sbjct 264 KSENYYQLIKRSGFVNSSLYSEQAEKRKQVYMLSSGSVLSFKPEGKILDLNLHGKHSIYR 323 Query 289 YARPLFLAL 297 +P+ L + Sbjct 324 MGKPIVLGV 332 >gi|301299524|ref|ZP_07205793.1| putative CRISPR-associated RAMP protein, Csm4 family [Lactobacillus salivarius ACS-116-V-Col5a] gi|300852871|gb|EFK80486.1| putative CRISPR-associated RAMP protein, Csm4 family [Lactobacillus salivarius ACS-116-V-Col5a] Length=257 Score = 120 bits (300), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 83/263 (32%), Positives = 132/263 (51%), Gaps = 29/263 (11%) Query 51 ELVACSTLRLTDLLPYVGPDYLVPKPLHS-----VRSDGSSMQK--KLAKKIGFLPAAQL 103 +L L+D P ++ +PKP+ + MQ+ K +KK+ ++ + Sbjct 8 DLSKSDNFFLSDSFPLKDGEFYLPKPIGYPKMPLISESTKEMQRNAKKSKKLQYIKYTDI 67 Query 104 GSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLATG 163 ++ G D+ +L G+ + +K+ + KK DPY VG F+ L++L Sbjct 68 EDYVKGNCDIGKLE------GISSFFSKSTVVT-KKGIDPYEVGITNFK--TSLYILTIK 118 Query 164 SESELGLLTRLLKGI--SALGGERTSGFGAFNLTESEAPAALTPTV-----DAASLMTLT 216 E LL L+ + S +GG+R+SG+G F + + + P + + + MTL Sbjct 119 HE----LLDMLMNSLQYSGIGGKRSSGYGRFTIEKLDIPNEFSKNIVINDSEYGVYMTLN 174 Query 217 TSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGIL 276 TS+P +DEL+ L A Y L K SGF A ST + LRK+D+YKF GS ++ + G I Sbjct 175 TSIPNNDELDVVLPTAEYLLEKSSGF-AYSTASKSLLRKQDLYKFVVGSTLTKTYSGNIF 233 Query 277 DVSLGG-NHPVYSYARPLFLALP 298 DV G HPV++YA+ LF LP Sbjct 234 DVRPDGFPHPVWNYAKGLFYKLP 256 >gi|258645684|ref|ZP_05733153.1| CRISPR-associated RAMP protein, Csm4 family [Dialister invisus DSM 15470] gi|260403052|gb|EEW96599.1| CRISPR-associated RAMP protein, Csm4 family [Dialister invisus DSM 15470] Length=328 Score = 115 bits (287), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 108/343 (32%), Positives = 163/343 (48%), Gaps = 61/343 (17%) Query 1 MNSRLFRFDFDR-THFGD----HGLESSTISCPADTLYSALCVEALRMGGQQLLG---EL 52 M + F F HFGD GL C ADT +SALC EA + Q+LL E Sbjct 1 MRHEIILFHFTSPVHFGDVAEGGGLGEILSYCRADTFFSALCREAADIS-QELLECVIEN 59 Query 53 VACSTLRLTDLLPYVGPDYL----VPKP-LHSVRSD-----------GSSMQKKLAKKIG 96 V LR++DL P+ ++ +P+P ++ SD S ++K KK Sbjct 60 VRLGNLRVSDLFPWKKANHCYELYLPRPVMYQKNSDLVETLSYEEVRAQSGERKKHKKRS 119 Query 97 FLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAG 156 F+ A+++ +L G + Q G + + +N + + PY +G + F DAG Sbjct 120 FIRASEMEIYLQGRD-----VSVQPDFGKEEIRTQ---YNAR-ERHPYGIGAYHFMPDAG 170 Query 157 LWLLATGSESELGLLTRLLK--GISALGGERTSGFGAFNLTESEAPAAL----TPTVDAA 210 L+ + +GSE L L+K G++ +GG+R+SGFG + + P AL T D Sbjct 171 LYFILSGSEELAERLEPLIKLLGMAGIGGKRSSGFGKYIFEDD--PLALSDEDTYGGDDV 228 Query 211 SL------------MTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADM--PLRKR 256 SL M+L++ LP E++ AG T +++KR GF S DM + Sbjct 229 SLYKMLCADHSDCYMSLSSFLPEKSEVKDVSAG-TGKIIKRGGFAWSR---DMISAAKTN 284 Query 257 DIYKFAAGSVFSRPFQGGILDVSLGGN-HPVYSYARPLFLALP 298 +Y A+G+ FS+ +G I DV+ G HPVY Y R LF+ LP Sbjct 285 SVYMIASGACFSKRLEGRIADVNNGSAPHPVYKYGRGLFVGLP 327 >gi|121533437|ref|ZP_01665265.1| CRISPR-associated RAMP protein, Csm4 family [Thermosinus carboxydivorans Nor1] gi|121307996|gb|EAX48910.1| CRISPR-associated RAMP protein, Csm4 family [Thermosinus carboxydivorans Nor1] Length=341 Score = 103 bits (258), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 100/341 (30%), Positives = 154/341 (46%), Gaps = 46/341 (13%) Query 1 MNSRLFRFDF-DRTHFGDHG----LESSTISCPADTLYSALCVEA--LRMGGQQLLGELV 53 M RL++ F FGD G L+ + ++ ADTL+SALC EA L Q L Sbjct 1 MLFRLYKLRFLTPVRFGDDGAAAGLDQARLAGRADTLFSALCSEAAMLSAAAPQRLAAAA 60 Query 54 ACSTLRLTDLLPYVGPD-------------YLVPKPLHSVRSDGSSMQKKLAKKIGFLPA 100 A L +TDL PY G + P + + + ++KKL K+ +LP Sbjct 61 ADGNLLVTDLFPYRGETLYLPRPLLPPDTAWQQPAAGRTASATAAHIKKKL-NKLPYLPV 119 Query 101 AQLGSFLDG--TADLKELAARQTK-IGVHAVSAKAAIH-----NGKKDADPYRVGYFRFE 152 L ++L T D + I + ++ +A+ +G++ PY V ++F Sbjct 120 RLLPAYLYWLRTGDSSQFDLDNANAIALSDIAKFSAVRVNARVDGERQTLPYVVTQYQFG 179 Query 153 LDAGLWLLATGSESEL-GLLTRLLKGIS--ALGGERTSGFGAFNLTES------------ 197 GL+ +A ++ +L + RL+ +S +GG+R++G G F L E Sbjct 180 AGCGLYFVAAAADQDLLDWIDRLIASLSYSGIGGKRSAGLGKFELAEDPIDMDETGVYAD 239 Query 198 -EAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKR 256 A +L DA M L+ P +E+ A LA Y L R GFVAS YA ++ Sbjct 240 DAALYSLLTATDADWYMALSCLWPLPNEV-ALLADGFYSLTARGGFVASPAYAPSAVKHH 298 Query 257 DIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLAL 297 ++ AAGS G + D++ GG HPVY Y +PL+ L Sbjct 299 SVHMLAAGSCLKAKAAGQVGDLAAGGKHPVYRYGKPLYAGL 339 >gi|323141260|ref|ZP_08076156.1| CRISPR-associated RAMP protein, Csm4 family [Phascolarctobacterium sp. YIT 12067] gi|322414217|gb|EFY05040.1| CRISPR-associated RAMP protein, Csm4 family [Phascolarctobacterium sp. YIT 12067] Length=337 Score = 103 bits (256), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 95/326 (30%), Positives = 143/326 (44%), Gaps = 47/326 (14%) Query 13 THFGDHG----LESSTISCPADTLYSALCVEALRMGGQ--QLLGELVACSTLRLTDLLPY 66 HFGD L+ ++ C ADTL++ALC EA G + L + A + + L PY Sbjct 15 VHFGDTANGGSLDKFSLQCSADTLFAALCNEAANKGSDAVETLVKKTAEGKIVFSSLFPY 74 Query 67 ---VGPD--YLVPKPLHSVRSDGSSMQK------------KLAKKIGFLPAAQLGSFLDG 109 V D + +PKPL + D K K KK ++ A+Q+ S L+ Sbjct 75 CRTVDDDLYFYLPKPLLKLEQDEQQSAKSFEEIKQLATKLKKQKKSTYIRASQINSLLES 134 Query 110 TADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLW-LLATGSESEL 168 + ++ A + V+ + A+ K PY VG + F +GL+ +L E E Sbjct 135 GSSDRQFAVPE--FAAPLVAGRVALREEK--PLPYYVGSYVFSEHSGLYFILGVEHEEEF 190 Query 169 GLLTRLL--KGISALGGERTSGFGAFNLTESE--------------APAALTPTVDAASL 212 L+ LL G S +GG+R+SG+G F L + E A A + + Sbjct 191 TLIKELLLSLGYSGIGGKRSSGYGKFELADDELELFDDGGVYDDDTAIALMLYNEKSKYQ 250 Query 213 MTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQ 272 M L P DEL A + Y+L+KR GF+ SS D +++ IY GS F Sbjct 251 MCLAPVCPKADEL-AVVKQGRYKLIKRGGFITSSAAKD-NIKRNSIYMLQEGSCFPERLC 308 Query 273 GGILDVSLGG-NHPVYSYARPLFLAL 297 G +L ++ G H VY +F+ L Sbjct 309 GQMLQQTVDGLAHDVYRDGIGMFVGL 334 >gi|341822664|emb|CCC73588.1| CRISPR-associated RAMP protein [Megasphaera elsdenii DSM 20460] Length=336 Score = 100 bits (248), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 95/341 (28%), Positives = 156/341 (46%), Gaps = 51/341 (14%) Query 1 MNSRLFRFDFDR-THFG--DHG--LESSTISCPADTLYSALCVEALRMGGQQ---LLGEL 52 M L+ FD HFG ++G LE S+++ AD+L+SALC E G ++ L E Sbjct 1 MKYALYPLQFDTPVHFGCAENGGKLEQSSLNYRADSLFSALCYELSLQGDEKGLTHLQEA 60 Query 53 VACSTLRLTDLLPYVGPD-----YLVPKPLHSVRSDG------------SSMQKKLAKKI 95 + L +DL PY+ D VPKP+ S+ ++ + Q+K KK+ Sbjct 61 IVKGKLVFSDLFPYIYDDTEELQLYVPKPILSIPAESRQETVDYDTFRRQATQQKRQKKL 120 Query 96 GFLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDA 155 ++ +QL F+ K + + G + + ++ + PY V +F +A Sbjct 121 SYIRISQLADFIQAMKAGKSFCSDEPCFGCGQLLTR--VNCTEAVPRPYYVHQIQFTEEA 178 Query 156 GLW-LLATGSESELGLLTRLLK--GISALGGERTSGFGAFNLTES----------EAPAA 202 GL+ L+ + + L LL+ G S +GG+R+SG+G F+ + E Sbjct 179 GLYGLVGYEDDEDWDWLQSLLELLGFSGIGGKRSSGYGKFHFRDDPIDMDELGVYEDDRI 238 Query 203 LTPTV---DAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIY 259 L + +A+ M L+ LPT E+ G Y L +RSGF++ +K DIY Sbjct 239 LYKGLTMSNASMYMCLSVLLPTPAEVIDVQEG-QYALCRRSGFLSPD--GGRMQKKNDIY 295 Query 260 KFAAGSVFSRPFQGGILDVSLGGN---HPVYSYARPLFLAL 297 AGS F + G + +V GG HPV+ Y + L++ + Sbjct 296 MIQAGSCFPKKLAGCMAEV--GGQDAVHPVWRYGKGLYVGV 334 >gi|334126728|ref|ZP_08500676.1| Csm4 family CRISPR-associated RAMP protein [Centipeda periodontii DSM 2778] gi|333391138|gb|EGK62259.1| Csm4 family CRISPR-associated RAMP protein [Centipeda periodontii DSM 2778] Length=333 Score = 97.8 bits (242), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 94/343 (28%), Positives = 147/343 (43%), Gaps = 58/343 (16%) Query 1 MNSRLFRFDFDR-THFGDHG----LESSTISCPADTLYSALCVEALRMGGQQLLGEL--- 52 M+ ++ FD HF G L+ + AD L+SALC E G L L Sbjct 1 MSYVIYPLQFDTAVHFAQAGRGGRLDEAGTEYGADALFSALCAELAATGEMDALAHLHER 60 Query 53 VACSTLRLTDLLPY----VGP-DYLVPKPLHSVRSDGSS-----------MQKKLAKKIG 96 VA L +DLLP+ VG ++ VP+P+ + G + ++K K + Sbjct 61 VAARELLFSDLLPWRVDAVGEMEFYVPRPVLRIEGTGEARANFVETCSRATERKKQKSMK 120 Query 97 FLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAG 156 +L A+ + ++D ++ A + S + ++ + + PY VG F F DAG Sbjct 121 YLRASCMADYVDA---MRTGAPFSSAAEFGTASLRQRVNTREAEPLPYYVGQFDFHRDAG 177 Query 157 LWLLATGSESELGLLTR---LLKGISALGGERTSGFGAFNLTESEAPAALTPTVDAASL- 212 L+LLA +E R + G+S +GG+RTSGFG F++ E E +DA + Sbjct 178 LYLLAYVHHAEDADFLRELLIWLGLSGIGGKRTSGFGKFHIAEDEI------VLDADGIY 231 Query 213 ------------------MTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLR 254 MT+ +P +EL GA YRL + GF+ + A + Sbjct 232 ADDAALYALLHAADAPWQMTIAPVVPAAEELPRVKDGA-YRLRRTGGFITAP--AHEAEK 288 Query 255 KRDIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLAL 297 K IY AGS G + ++ HPV+ Y L+L + Sbjct 289 KNSIYLIDAGSCLRTRIGGSLAELCTYDGHPVWRYGFGLYLGV 331 >gi|313894815|ref|ZP_07828375.1| CRISPR-associated RAMP protein, Csm4 family [Selenomonas sp. oral taxon 137 str. F0430] gi|312976496|gb|EFR41951.1| CRISPR-associated RAMP protein, Csm4 family [Selenomonas sp. oral taxon 137 str. F0430] Length=331 Score = 93.2 bits (230), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 100/330 (31%), Positives = 150/330 (46%), Gaps = 49/330 (14%) Query 1 MNSRLFRFDFDR-THFG--DHG--LESSTISCPADTLYSALCVEALRMGGQQLLGELV-A 54 M L++ FD HFG + G L ++ +S P+DTL+SALC E G ++ L + Sbjct 1 MAYYLYQLAFDAPVHFGMAEQGGSLAAAGMSYPSDTLFSALCCELAAAGEEERLRAFIEK 60 Query 55 CST--LRLTDLLPYVGPD-----YLVPKPLHSVRSDGS-----------SMQKKLAKKIG 96 C + L+DLLPY D YL+ L +++ + + S +K KKI Sbjct 61 CRAGDIILSDLLPYREEDGEVHYYLLKPTLAAMQPNAAPPENLTGARAQSGARKQMKKIA 120 Query 97 FLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAG 156 +L A++L +LD R + + ++ K + +PY VG F G Sbjct 121 YLRASRLTEYLDAQQSGNPFDER-GEFCTYGLTTKVNC----RAQEPYPVGSISFHAKCG 175 Query 157 LW-LLATGSESELGLLTRLLK--GISALGGERTSGFGAFNLTE---------SEAPAALT 204 L+ +L E + +T L G+S +GG+R++G+G F+L + SE AAL Sbjct 176 LYAVLYLRDEDDAARMTELFTYLGLSGIGGKRSAGWGKFHLEDDPYDLVDAFSEDDAALH 235 Query 205 ---PTVDAASLMTLTTSLPTDDELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKF 261 +A M L++ LP D E AL TY L KRSGF+ + A +K +Y Sbjct 236 AFLENENAPRQMLLSSLLP-DPEDVGALRAGTYELHKRSGFI-TQVGAGGVRKKHSVYML 293 Query 262 AAGSVFSRPFQGGILDVSLGGNHPVYSYAR 291 +AGS R G I V G P Y R Sbjct 294 SAGSCLPRRISGTIAHV---GKEPGYEVLR 320 >gi|292669139|ref|ZP_06602565.1| csm4 family CRISPR-associated ramp protein [Selenomonas noxia ATCC 43541] gi|292649191|gb|EFF67163.1| csm4 family CRISPR-associated ramp protein [Selenomonas noxia ATCC 43541] Length=336 Score = 92.4 bits (228), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 85/306 (28%), Positives = 135/306 (45%), Gaps = 40/306 (13%) Query 20 LESSTISCPADTLYSALCVEALRMGGQQLLG---ELVACSTLRLTDLLPYVGPDY----- 71 L+ + + PAD L+ ALC E G + LG E V LRL+DLLP+ ++ Sbjct 25 LDEACMEYPADALFGALCAELAASGETEELGRLAETVERGDLRLSDLLPWQRREHDGALA 84 Query 72 -LVPKPLHSVR-------------SDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELA 117 +P+P+ + + ++M+KK KK+ ++ A ++ ++ Sbjct 85 LFLPRPVLRIEHTQAQEREDYRSTCENATMRKK-QKKLKYIRACRMQDYICAMQSGNPFE 143 Query 118 ARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAGLWLLA-TGSESELGLLTRLLK 176 R+ S + ++ ++ PY V F F +AGL+L+A E + L RLL Sbjct 144 DREFDANFGMESLRQRVNRRGEEPLPYYVAQFDFRTEAGLYLIACVRDEKTISWLHRLLV 203 Query 177 --GISALGGERTSGFGAFNLTE--------SEAPAALTPTVDAAS---LMTLTTSLPTDD 223 G + +GG+RTSG+G F E AAL + A S + L LPT D Sbjct 204 WLGTAGIGGKRTSGYGKFRAGEIIHMDADDGGDIAALRDMLAADSAPWQLALAPVLPTAD 263 Query 224 ELEAALAGATYRLVKRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLGGN 283 +L GA YRL + GF++ ++ +K +Y AGS F G + Sbjct 264 DLATVKRGA-YRLRRAGGFISYPVHS--AEKKNSVYLLDAGSCFPARISGTCGMLGTHDG 320 Query 284 HPVYSY 289 HPV+ Y Sbjct 321 HPVWRY 326 >gi|312899097|ref|ZP_07758475.1| CRISPR-associated RAMP protein, Csm4 family [Megasphaera micronuciformis F0359] gi|310619764|gb|EFQ03346.1| CRISPR-associated RAMP protein, Csm4 family [Megasphaera micronuciformis F0359] Length=334 Score = 90.9 bits (224), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 92/341 (27%), Positives = 143/341 (42%), Gaps = 54/341 (15%) Query 1 MNSRLFRFDFDR-THFGD----HGLESSTISCPADTLYSALCVEALRMGGQQLLGELVAC 55 M S L++ FD HFG GLES + +D L+S+LC E G + +LV Sbjct 2 MVSYLYQLKFDTPVHFGTIEAGDGLESVVYTYESDRLFSSLCCELAENGDSNKILDLVGA 61 Query 56 S---TLRLTDLLPYVGPD----YLVPKPLHSVRSDGS------------SMQKKLAKKIG 96 + L L+DL P+ D +PKP+ S+ + S S+ KK KK+ Sbjct 62 ADSGKLILSDLFPFAKVDGDCRLYIPKPVLSIERNESDEIRSYTEACKASVAKKTNKKLE 121 Query 97 FLPAAQLGSFLDGTADLKELAARQTKIGVHAVSAKAAIHNGKKDADPYRVGYFRFELDAG 156 F+ +++ ++ + G ++ + + K PY VG F F + G Sbjct 122 FIRVSKVDEYIQSLKSNRAFT-EDDDFGASWLTEQVSCRGDK--PLPYYVGTFVFAKNTG 178 Query 157 LWLLATGSES----ELGLLTRLLKGISALGGERTSGFGAFNLTES-----EAPAALTPTV 207 L+ + G E L LL +L G+S +GG+R+SG+G F + E P P Sbjct 179 LYGIIQGEERIVQRSLDLLEQL--GLSGIGGKRSSGYGKFRFHDDPFILDEEP----PYD 232 Query 208 DAASLMTLTTSLPTDDELEAALAGAT-----------YRLVKRSGFVASSTYADMPLRKR 256 DA L + +L Y L KRSGFV+S + + ++ Sbjct 233 DAIELKRRMDDKTAQWHMNMSLLIPDIGDIDDIKKGFYSLKKRSGFVSSLGFGYVH-KRH 291 Query 257 DIYKFAAGSVFSRPFQGGILDVSLGGNHPVYSYARPLFLAL 297 DIY A+GS F G + + H VY + L+L + Sbjct 292 DIYGIASGSCFRNQPAGKVAAMRTDTGHDVYRNGKALYLGV 332 >gi|344997572|ref|YP_004799915.1| CRISPR-associated RAMP protein, Csm4 family [Caldicellulosiruptor lactoaceticus 6A] gi|343965791|gb|AEM74938.1| CRISPR-associated RAMP protein, Csm4 family [Caldicellulosiruptor lactoaceticus 6A] Length=336 Score = 88.2 bits (217), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 86/304 (29%), Positives = 136/304 (45%), Gaps = 42/304 (13%) Query 29 ADTLYSALCVEALRMGGQQLLGELV-----ACSTLRLTDLLPYVGPDYLVPKP----LHS 79 +DTL S + + G EL+ ++ +PYV ++ VPKP LH Sbjct 35 SDTLMSGIINAYSLLYGNSSTNELLDGFLRKSPPFEVSSTMPYVQGEFFVPKPAGLNLHH 94 Query 80 VRSDG--SSMQKKLAKKIGFLPAAQL-----------GSFLDGTADLKELAARQTKIGVH 126 + +G K KKI F+ L GSFL L + + I + Sbjct 95 YKDEGKIEVENDKELKKIKFIRENDLLYNFPDKYKAAGSFLLPRDMLYKFVESKKHISLG 154 Query 127 AVS--AKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGS----ESELGLLTRLLKGISA 180 V A+ +I ++ Y +F FE AGLW + E ++ RLL G Sbjct 155 KVKERARVSIDRLSSSSNIYYFSHFEFEESAGLWFYLRINDQSLEEKIKAAIRLL-GDEG 213 Query 181 LGGERTSGFGAF--NLTESEAPAALTPTVDAASLMTLTTSLP-TDDELEAALAGATYRLV 237 LGG+RT G G+F N ES P A M+L+ P ++DE+++A+ +Y ++ Sbjct 214 LGGDRTCGLGSFEANFEESSMPEE---NDSAKYYMSLSLVNPQSEDEIKSAI---SYEIL 267 Query 238 KRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLG--GNHPVYSYARPLFL 295 RSG++ S A + ++++ + F+ G+VFS G ++DV+ H VY +A L Sbjct 268 TRSGYIYSK--AGLGIKRKALRVFSEGTVFSGKVCGRVVDVTPQKFSQHRVYCFALAFLL 325 Query 296 ALPE 299 LPE Sbjct 326 PLPE 329 >gi|312794662|ref|YP_004027585.1| crispr-associated ramp protein, csm4 family [Caldicellulosiruptor kristjanssonii 177R1B] gi|312181802|gb|ADQ41972.1| CRISPR-associated RAMP protein, Csm4 family [Caldicellulosiruptor kristjanssonii 177R1B] Length=336 Score = 87.8 bits (216), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 86/304 (29%), Positives = 135/304 (45%), Gaps = 42/304 (13%) Query 29 ADTLYSALCVEALRMGGQQLLGELV-----ACSTLRLTDLLPYVGPDYLVPKP----LHS 79 +DTL S + + G EL+ ++ +PYV ++ VPKP LH Sbjct 35 SDTLMSGIINAYSLLYGNSSTNELLDGFLRKSPPFEVSSTMPYVQGEFFVPKPVGLNLHH 94 Query 80 VRSDG--SSMQKKLAKKIGFLPAAQL-----------GSFLDGTADLKELAARQTKIGVH 126 + +G K KKI F+ L GSFL L + + I + Sbjct 95 YKDEGKIEVENDKELKKIKFIRENDLLYNFPDKYKVAGSFLLPKDMLYKFVESKKAISLG 154 Query 127 AVS--AKAAIHNGKKDADPYRVGYFRFELDAGLWLLATGS----ESELGLLTRLLKGISA 180 V A+ +I ++ Y +F FE AGLW + E ++ RLL G Sbjct 155 KVKERARVSIDRLSSSSNIYYFSHFEFESSAGLWFYLRINDQSLEEKIKAAIRLL-GDEG 213 Query 181 LGGERTSGFGAF--NLTESEAPAALTPTVDAASLMTLTTSLP-TDDELEAALAGATYRLV 237 LGG+RT G G+F N ES P A M+L+ P ++DE++ A+ +Y ++ Sbjct 214 LGGDRTCGLGSFEANFEESSMPEE---NDSAKYYMSLSLVNPQSEDEIKNAI---SYEIL 267 Query 238 KRSGFVASSTYADMPLRKRDIYKFAAGSVFSRPFQGGILDVSLG--GNHPVYSYARPLFL 295 RSG++ S A + ++++ + F+ G+VFS G ++DV+ H VY +A L Sbjct 268 TRSGYIYSK--AGLGIKRKAVRVFSEGTVFSGKVCGRVVDVTPQKFSQHRVYCFALAFLL 325 Query 296 ALPE 299 LPE Sbjct 326 PLPE 329 >gi|345303032|ref|YP_004824934.1| CRISPR-associated RAMP protein, Csm4 family [Rhodothermus marinus SG0.5JP17-172] gi|345112265|gb|AEN73097.1| CRISPR-associated RAMP protein, Csm4 family [Rhodothermus marinus SG0.5JP17-172] Length=325 Score = 87.4 bits (215), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 84/309 (28%), Positives = 137/309 (45%), Gaps = 36/309 (11%) Query 19 GLESSTISCPADTLYSALCVEALRMGGQQLLGELVACSTLRLTDLLPYVGPDYLVPKPLH 78 G ES + + P+DTL+SA+CV A + G + + L+ +RL+ P+VG +Y P+PL Sbjct 22 GEESVSPTVPSDTLFSAVCVSAFWLYGAEGVERLLKPGAVRLSSTFPFVGTEYFFPRPLS 81 Query 79 ---SVRSDGSSMQKKLAKKIGFLPAAQLGSFLDGTADLKELAARQTK------------- 122 + ++ + K++ KK+ +L L+GT E+ + Q + Sbjct 82 FFPKIPNEQYELLKRI-KKVRYLSRTLFEQVLEGTQ--PEIRSDQIRGLFWFAGPPPDEP 138 Query 123 IGVHAVSAKAAIHNGKKDADPYRVG--YFRFELDAGLWLLATGSESELGLLTR---LLKG 177 + V + A+ + ++ Y +F LDAGL+ LA + ++ L L Sbjct 139 VMQTEVRPRVALDRVTQASEIYHFAEVHFNPRLDAGLFFLAQFEDPKVQQLFESALALLA 198 Query 178 ISALGGERTSGFGAFNLTESEAPAALTPTVDAASLMTLTTSLPTDDELEAALAGATYRLV 237 +G +RT G G F E + D A L++L P ++ + A + Y LV Sbjct 199 DEGIGADRTMGKGWFRWEREELTIRVPEATDRAVLLSLYNPTP-EEAVAIAPYDSCYALV 257 Query 238 KRSGFVASSTYADMPLRKRDIYKFAAGSV---FSRPFQGGILDVSLGGN------HPVYS 288 R G+V + M LR+R + FA GSV S+ G L V L HPVY Sbjct 258 TRRGWV--TVPGAMTLRRRPVRFFAEGSVLRFISQHMPQGRLVVVLSEKDAPELTHPVYR 315 Query 289 YARPLFLAL 297 + L L + Sbjct 316 NGQALALPI 324 Lambda K H 0.319 0.135 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Effective search space used: 505781532318 Database: All non-redundant GenBank CDS translations+PDB+SwissProt+PIR+PRF excluding environmental samples from WGS projects Posted date: Sep 5, 2011 4:36 AM Number of letters in database: 5,219,829,388 Number of sequences in database: 15,229,318 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40